LOCUS       DAZKPE010000001       100710 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000001 DAZKPE010000000
VERSION     DAZKPE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.001"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(554..2167)
                     /locus_tag="ACG930_000001"
     CDS             complement(554..2167)
                     /locus_tag="ACG930_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0517202.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="ACG930_000002"
     CDS             complement(2308..3216)
                     /locus_tag="ACG930_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517203.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3399..4523
                     /locus_tag="ACG930_000003"
     CDS             3399..4523
                     /locus_tag="ACG930_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0517204.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4750..5667
                     /locus_tag="ACG930_000004"
     CDS             4750..5667
                     /locus_tag="ACG930_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517205.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5660..6493
                     /locus_tag="ACG930_000005"
     CDS             5660..6493
                     /locus_tag="ACG930_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517206.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6576..7694
                     /locus_tag="ACG930_000006"
     CDS             6576..7694
                     /locus_tag="ACG930_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0517207.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7715..9586
                     /locus_tag="ACG930_000007"
     CDS             7715..9586
                     /locus_tag="ACG930_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFQ0517208.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            9580..10803
                     /locus_tag="ACG930_000008"
     CDS             9580..10803
                     /locus_tag="ACG930_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0517209.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10889..12823)
                     /locus_tag="ACG930_000009"
     CDS             complement(10889..12823)
                     /locus_tag="ACG930_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0517210.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13049..13705
                     /locus_tag="ACG930_000010"
     CDS             13049..13705
                     /locus_tag="ACG930_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFQ0517211.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13779..14132)
                     /locus_tag="ACG930_000011"
     CDS             complement(13779..14132)
                     /locus_tag="ACG930_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0517212.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14324..15253
                     /locus_tag="ACG930_000012"
     CDS             14324..15253
                     /locus_tag="ACG930_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFQ0517213.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15264..16100
                     /locus_tag="ACG930_000013"
     CDS             15264..16100
                     /locus_tag="ACG930_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFQ0517214.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16348..17124
                     /locus_tag="ACG930_000014"
     CDS             16348..17124
                     /locus_tag="ACG930_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0517215.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17300..18043
                     /locus_tag="ACG930_000015"
     CDS             17300..18043
                     /locus_tag="ACG930_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517216.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18036..19616
                     /locus_tag="ACG930_000016"
     CDS             18036..19616
                     /locus_tag="ACG930_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFQ0517217.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19867..20346)
                     /locus_tag="ACG930_000017"
     CDS             complement(19867..20346)
                     /locus_tag="ACG930_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFQ0517218.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20362..21114)
                     /locus_tag="ACG930_000018"
     CDS             complement(20362..21114)
                     /locus_tag="ACG930_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFQ0517219.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21231..21301
                     /locus_tag="ACG930_000019"
     tRNA            21231..21301
                     /locus_tag="ACG930_000019"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21263..21265,aa:Gly,seq:ccc)
     gene            21662..22387
                     /locus_tag="ACG930_000020"
     CDS             21662..22387
                     /locus_tag="ACG930_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFQ0517220.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22642..22908
                     /locus_tag="ACG930_000021"
     CDS             22642..22908
                     /locus_tag="ACG930_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFQ0517221.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22905..23336
                     /gene="ruvX"
                     /locus_tag="ACG930_000022"
     CDS             22905..23336
                     /gene="ruvX"
                     /locus_tag="ACG930_000022"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFQ0517222.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23361..23666
                     /locus_tag="ACG930_000023"
     CDS             23361..23666
                     /locus_tag="ACG930_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFQ0517223.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23747..24892)
                     /locus_tag="ACG930_000024"
     CDS             complement(23747..24892)
                     /locus_tag="ACG930_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0517224.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24953..25600)
                     /locus_tag="ACG930_000025"
     CDS             complement(24953..25600)
                     /locus_tag="ACG930_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517225.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25795..26088
                     /locus_tag="ACG930_000026"
     CDS             25795..26088
                     /locus_tag="ACG930_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517226.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26132..26443
                     /locus_tag="ACG930_000027"
     CDS             26132..26443
                     /locus_tag="ACG930_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517227.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26440..27064
                     /locus_tag="ACG930_000028"
                     /pseudo
     CDS             26440..27064
                     /locus_tag="ACG930_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27205..27363
                     /locus_tag="ACG930_000029"
     CDS             27205..27363
                     /locus_tag="ACG930_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517228.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27364..27726
                     /locus_tag="ACG930_000030"
     CDS             27364..27726
                     /locus_tag="ACG930_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517229.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27763..28611
                     /locus_tag="ACG930_000031"
     CDS             27763..28611
                     /locus_tag="ACG930_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFQ0517230.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28601..30076
                     /locus_tag="ACG930_000032"
     CDS             28601..30076
                     /locus_tag="ACG930_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFQ0517231.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30342..30749
                     /locus_tag="ACG930_000033"
     CDS             30342..30749
                     /locus_tag="ACG930_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFQ0517232.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30752..30967
                     /locus_tag="ACG930_000034"
     CDS             30752..30967
                     /locus_tag="ACG930_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517233.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30971..31351
                     /locus_tag="ACG930_000035"
     CDS             30971..31351
                     /locus_tag="ACG930_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFQ0517234.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31485..31640
                     /locus_tag="ACG930_000036"
     CDS             31485..31640
                     /locus_tag="ACG930_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFQ0517235.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31709..32182
                     /locus_tag="ACG930_000037"
     CDS             31709..32182
                     /locus_tag="ACG930_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFQ0517236.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32179..33873
                     /locus_tag="ACG930_000038"
     CDS             32179..33873
                     /locus_tag="ACG930_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFQ0517237.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33839..34024
                     /locus_tag="ACG930_000039"
     CDS             33839..34024
                     /locus_tag="ACG930_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517238.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34028..35203
                     /locus_tag="ACG930_000040"
     CDS             34028..35203
                     /locus_tag="ACG930_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0517239.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35196..36719
                     /locus_tag="ACG930_000041"
     CDS             35196..36719
                     /locus_tag="ACG930_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFQ0517240.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36775..37059
                     /locus_tag="ACG930_000042"
     CDS             36775..37059
                     /locus_tag="ACG930_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFQ0517241.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37046..37381
                     /locus_tag="ACG930_000043"
     CDS             37046..37381
                     /locus_tag="ACG930_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFQ0517242.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37676..38302
                     /locus_tag="ACG930_000044"
     CDS             37676..38302
                     /locus_tag="ACG930_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517243.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39044..39880
                     /locus_tag="ACG930_000045"
     CDS             39044..39880
                     /locus_tag="ACG930_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFQ0517244.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39944..40375
                     /locus_tag="ACG930_000046"
     CDS             39944..40375
                     /locus_tag="ACG930_000046"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0517245.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40437..41759)
                     /locus_tag="ACG930_000047"
     CDS             complement(40437..41759)
                     /locus_tag="ACG930_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFQ0517246.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41913..43553)
                     /locus_tag="ACG930_000048"
     CDS             complement(41913..43553)
                     /locus_tag="ACG930_000048"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFQ0517247.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43886..44356
                     /locus_tag="ACG930_000049"
     CDS             43886..44356
                     /locus_tag="ACG930_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFQ0517248.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44578..45681
                     /locus_tag="ACG930_000050"
     CDS             44578..45681
                     /locus_tag="ACG930_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFQ0517249.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45965..46645
                     /locus_tag="ACG930_000051"
     CDS             45965..46645
                     /locus_tag="ACG930_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0517250.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46735..47769
                     /locus_tag="ACG930_000052"
     CDS             46735..47769
                     /locus_tag="ACG930_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFQ0517251.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47783..48118
                     /locus_tag="ACG930_000053"
     CDS             47783..48118
                     /locus_tag="ACG930_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517252.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48102..50582
                     /locus_tag="ACG930_000054"
     CDS             48102..50582
                     /locus_tag="ACG930_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517253.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50638..52197
                     /locus_tag="ACG930_000055"
     CDS             50638..52197
                     /locus_tag="ACG930_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517254.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52194..53558
                     /locus_tag="ACG930_000056"
     CDS             52194..53558
                     /locus_tag="ACG930_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0517255.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53729..54799
                     /locus_tag="ACG930_000057"
     CDS             53729..54799
                     /locus_tag="ACG930_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517256.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54814..55482
                     /locus_tag="ACG930_000058"
     CDS             54814..55482
                     /locus_tag="ACG930_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517257.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55502..56080
                     /locus_tag="ACG930_000059"
     CDS             55502..56080
                     /locus_tag="ACG930_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0517258.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56481..57392
                     /locus_tag="ACG930_000060"
     CDS             56481..57392
                     /locus_tag="ACG930_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFQ0517259.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57480..58397)
                     /gene="rnhC"
                     /locus_tag="ACG930_000061"
     CDS             complement(57480..58397)
                     /gene="rnhC"
                     /locus_tag="ACG930_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFQ0517260.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58599..59036
                     /gene="zapA"
                     /locus_tag="ACG930_000062"
     CDS             58599..59036
                     /gene="zapA"
                     /locus_tag="ACG930_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFQ0517261.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59095..59643
                     /locus_tag="ACG930_000063"
     CDS             59095..59643
                     /locus_tag="ACG930_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFQ0517262.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59758..62118
                     /locus_tag="ACG930_000064"
                     /pseudo
     CDS             59758..62118
                     /locus_tag="ACG930_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            62205..62519
                     /gene="trxA"
                     /locus_tag="ACG930_000065"
     CDS             62205..62519
                     /gene="trxA"
                     /locus_tag="ACG930_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFQ0517263.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62701..64479
                     /gene="uvrC"
                     /locus_tag="ACG930_000066"
     CDS             62701..64479
                     /gene="uvrC"
                     /locus_tag="ACG930_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFQ0517264.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64624..65523
                     /locus_tag="ACG930_000067"
     CDS             64624..65523
                     /locus_tag="ACG930_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517265.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65516..66778
                     /locus_tag="ACG930_000068"
     CDS             65516..66778
                     /locus_tag="ACG930_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517266.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66939..68837
                     /locus_tag="ACG930_000069"
     CDS             66939..68837
                     /locus_tag="ACG930_000069"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFQ0517267.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69167..69886)
                     /locus_tag="ACG930_000070"
     CDS             complement(69167..69886)
                     /locus_tag="ACG930_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFQ0517268.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    70076..70123
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            70223..70555
                     /locus_tag="ACG930_000071"
     CDS             70223..70555
                     /locus_tag="ACG930_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517269.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70542..72545
                     /locus_tag="ACG930_000072"
     CDS             70542..72545
                     /locus_tag="ACG930_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFQ0517270.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72564..73034
                     /locus_tag="ACG930_000073"
     CDS             72564..73034
                     /locus_tag="ACG930_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFQ0517271.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73055..73639
                     /locus_tag="ACG930_000074"
     CDS             73055..73639
                     /locus_tag="ACG930_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFQ0517272.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73654..74640
                     /locus_tag="ACG930_000075"
     CDS             73654..74640
                     /locus_tag="ACG930_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFQ0517273.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74630..74941
                     /locus_tag="ACG930_000076"
     CDS             74630..74941
                     /locus_tag="ACG930_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFQ0517274.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74963..76744
                     /locus_tag="ACG930_000077"
     CDS             74963..76744
                     /locus_tag="ACG930_000077"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFQ0517275.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76737..78113
                     /locus_tag="ACG930_000078"
     CDS             76737..78113
                     /locus_tag="ACG930_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFQ0517276.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78120..78755
                     /locus_tag="ACG930_000079"
     CDS             78120..78755
                     /locus_tag="ACG930_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFQ0517277.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78785..80140
                     /locus_tag="ACG930_000080"
     CDS             78785..80140
                     /locus_tag="ACG930_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFQ0517278.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80332..81726)
                     /locus_tag="ACG930_000081"
     CDS             complement(80332..81726)
                     /locus_tag="ACG930_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFQ0517279.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81818..82789
                     /locus_tag="ACG930_000082"
     CDS             81818..82789
                     /locus_tag="ACG930_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFQ0517280.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82786..83568
                     /locus_tag="ACG930_000083"
     CDS             82786..83568
                     /locus_tag="ACG930_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFQ0517281.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83737..84108)
                     /locus_tag="ACG930_000084"
     CDS             complement(83737..84108)
                     /locus_tag="ACG930_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0517282.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84242..84685
                     /locus_tag="ACG930_000085"
     CDS             84242..84685
                     /locus_tag="ACG930_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFQ0517283.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84728..85537)
                     /gene="yidA"
                     /locus_tag="ACG930_000086"
     CDS             complement(84728..85537)
                     /gene="yidA"
                     /locus_tag="ACG930_000086"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFQ0517284.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85556..86923)
                     /locus_tag="ACG930_000087"
     CDS             complement(85556..86923)
                     /locus_tag="ACG930_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0517285.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86907..87737)
                     /locus_tag="ACG930_000088"
     CDS             complement(86907..87737)
                     /locus_tag="ACG930_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFQ0517286.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87900..88337
                     /locus_tag="ACG930_000089"
     CDS             87900..88337
                     /locus_tag="ACG930_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFQ0517287.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88413..89033
                     /gene="rpoE"
                     /locus_tag="ACG930_000090"
     CDS             88413..89033
                     /gene="rpoE"
                     /locus_tag="ACG930_000090"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFQ0517288.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89222..89728
                     /locus_tag="ACG930_000091"
     CDS             89222..89728
                     /locus_tag="ACG930_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFQ0517289.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89745..90644
                     /locus_tag="ACG930_000092"
     CDS             89745..90644
                     /locus_tag="ACG930_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFQ0517290.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90731..91615
                     /locus_tag="ACG930_000093"
     CDS             90731..91615
                     /locus_tag="ACG930_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0517291.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91807..91878)
                     /locus_tag="ACG930_000094"
     tRNA            complement(91807..91878)
                     /locus_tag="ACG930_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91843..91845),aa:Arg,seq:ccg)
     gene            91938..93272
                     /gene="rpoN"
                     /locus_tag="ACG930_000095"
     CDS             91938..93272
                     /gene="rpoN"
                     /locus_tag="ACG930_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFQ0517292.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93421..94512
                     /locus_tag="ACG930_000096"
     CDS             93421..94512
                     /locus_tag="ACG930_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFQ0517293.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94553..95554
                     /gene="gap"
                     /locus_tag="ACG930_000097"
     CDS             94553..95554
                     /gene="gap"
                     /locus_tag="ACG930_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFQ0517294.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95664..96854
                     /gene="pgk"
                     /locus_tag="ACG930_000098"
     CDS             95664..96854
                     /gene="pgk"
                     /locus_tag="ACG930_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFQ0517295.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96958..97713
                     /gene="tpiA"
                     /locus_tag="ACG930_000099"
     CDS             96958..97713
                     /gene="tpiA"
                     /locus_tag="ACG930_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFQ0517296.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97829..99127
                     /gene="eno"
                     /locus_tag="ACG930_000100"
     CDS             97829..99127
                     /gene="eno"
                     /locus_tag="ACG930_000100"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFQ0517297.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99526..100665
                     /locus_tag="ACG930_000101"
     CDS             99526..100665
                     /locus_tag="ACG930_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFQ0517298.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33405 a        17202 c        20784 g        29319 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa acgacaagta
     3301 aaatattttt ttatataaat atttgtgtta ctaattccgt taatatacat aagtgaaagc
     3361 gttttatata agaacttgaa aagaaagaag ggatagacat gaaaaaaaga tacaaattgg
     3421 tgatagcttt gctaaacatt accctattat tcagcttaag tgcatgtgga aaaactaacg
     3481 aagaagtaac agcaaacatc gcagatccaa tgataaaaaa agccactaca ttagaagtat
     3541 atgtcgcaaa cggcaaactg acaaactatg ttgaaaatgc tgcaaaaatc tataaccgca
     3601 aaactggagc aaatattgac ttaaaaattg tgaatgtagc ttcgggaaca gcaacagtac
     3661 aaatgatcac cccaaaattg gtaacacacg aagatatgcc ggatattatc tccatggcag
     3721 acacttcagc agcaggtgtg ctggaaaaat ttcaagatgc tttttatagt gctgatgaat
     3781 atggatttta tgacaaatat ggcgatcagt tttatgatca aaaattgaat attttgcgtc
     3841 aacaaacgag taatgaaacg attattcctt gggctagtga ttttacccca gcactttgtt
     3901 attatcaacc aaaaaaattt gctgaaatag gtgtagattt tgaagaaatc agttcttggg
     3961 aagaatatat ccaggtggca aaagcattaa aagaaaaaac tggtagtttt ggaattgcct
     4021 tgccagaatc tggggaccaa gaattgttta tcaacatgct agcccagcag aatcaatctt
     4081 tgcttgatga agaaggaaat atccgtctga atactaaaga agcgaaacat gctgcaaagt
     4141 taatcaaaga aatgatcgac tcagatattg tacatttcta cggtgcacaa gatgctgaga
     4201 aagcatttca agaatctgca atgtttgttg ctggcggctg gtatgctacg aatatgtctt
     4261 tgaattttcc tgatgcatct gacaaatggc gcatggctcc actgattcct ttttcaaaag
     4321 aaaatccagg aaaaggtgca gtatcaggag gatcaagttt ttatgtccct aaagatgcaa
     4381 aaaatccaca agtggcacaa caatttctta catttatgct gacagatgaa gaatgcttag
     4441 ccaacgcact ggagctgggc gtggctacat ctaactcatt ggcctatcaa acagaagcag
     4501 ctgagaaaaa gtttgactac taaggaggac aaaaatacta tgaactattg aataaaatca
     4561 atgaaaatac atcaaatact gttttaccag ccacttattc agatgctacg tcttatttga
     4621 ctaccgctgc atataactat tggcaaacag gtgattttga aaattcatat ctaaaagaag
     4681 cagaaaattt tgctcataag tacggcgtaa aattaactgg tgattaaaaa atattaggag
     4741 gacttaacga tgatgcaatc ttcgttacca agcaagacaa taaagaacag caagaaaaaa
     4801 gcaacagata cgtctcataa aaaaagtgct tatggattgg tcacaccttt tgttattttc
     4861 tttattgtga cgattttgat tcccatcatt atctcgtttg cttttagttt tatgaaaatt
     4921 ggctactcat ttgaatttgt tggatttgac aattatctag ctatcttccg agatccattg
     4981 tttattaaat cttacacgaa tgttttgatt atcatggcag gatcaattcc aataacgatg
     5041 ctattagcta tttactttgc tgttttattg aattcagcac agttaaaagg aaaaggattt
     5101 tttagaactg tctattatat tccaaccatt acatcaacgg tggctgtagc ttccgtattc
     5161 atgacttttt tcaatccgac tgggttattc aatggatttt tgaatgcgct aggaattaac
     5221 ggtgtacagt ggttaacaaa tcctttttgg atacgaatat caatgatcat cacgatgatt
     5281 tggcttagtg taggatataa cactatttta tttttagctg gtcttcaagg gatttctaaa
     5341 gagatatacg aaagtgctga aatagatgga gcatcgaaat ttcggcaatt ctttttatta
     5401 acgatcccca tgctaaagcc aatcatttta atggccacag ttttagccac tatcaatggc
     5461 ttgggtaatt tcaatatccc aaatatattc tttgggactt ccaatggacc agaaaattca
     5521 gctttggtcg taggagtcaa tttatataaa acaagttttg aaatggttga ttttggaaaa
     5581 gcctctgcta ttgcctggac gatggtgttt gtatctgtta tattatcggc tattcaattt
     5641 aaattcggag gtgataaaaa tgactaaaca aaagatacaa agcagaattt ttacgtacgt
     5701 cattattgtg tttggtgcct taatattttt gatgccatat ttatatatga ttgtagcttc
     5761 aacgcaaagt aatcaagaaa ttttaagtgg cggaatcaat ttcaagtttg gggatatgct
     5821 attaaaaaac tggcaagcca tcatggcgag atataattat cccttgatta tttggaattc
     5881 gattgttatt gctgtaatca gtacagtttt agctacagcc agttctacaa tggcgggtta
     5941 tgcattagca aagtatcgtt ttatggggaa taaactgttg ttcaatacag ttatgctatc
     6001 taggatggtg ccttttttta ccacattgat tcctttattt tacattatga gtcgtttagg
     6061 attatcgaat acttatgcag gtgtgatcat cccttcgatt gccagtacaa cttcagtgtt
     6121 tatgatgcga caatatagca gtcaatttcc tacagcactg atggaggctg ccagaatcga
     6181 tggtgccaat gagtgggtga tttttacgaa aatcgctgta ccgattttat cacctacgat
     6241 tattactagt ggtttactta tctttatggg aagttggaat caatatctat ttccattagt
     6301 catgctttca gataaagata aatatacggt tcccttaatt atcaaaaata tgacggtttc
     6361 tagtacaggt gagccaatta attatggcgc aattatgcta attttagcaa cttcagtgat
     6421 cccaatggtc ttgatttatg tgtgggcgca gtctaaattt aaggagaatg acattggagc
     6481 tgcaaataag taaaaaaaat aacgaatgtt aaccatctag ttcgttctag gagcaactcc
     6541 acattcataa aaattaaaag aatggcggga tatccatgaa tgaacagacg aaggaatggt
     6601 caagaaaaat tttgaatgta gcttctgaaa agatagatgc ggaattagac agaatgggga
     6661 ataaaattcc atatatttct tacaacggaa aatatacaga cgtaataaag gacagaggaa
     6721 tcgactggtg gaccaatggt ttttggagtg gtattttatg gcagctcttt cacaagacaa
     6781 aacgagaaaa gttcaaagag gcagcaatac aacaagaaca attattagaa tctgccctgt
     6841 accatttttc agacgttcat catgatgtag gttttttatt cttaccatcg gctattgcac
     6901 attatcaaca gtctcaaaac aaacatagtc gacaactagg gttacatgca gctacggtac
     6961 ttgctggacg ctataatatt tcagggaact atttagtagc atggaatgac cataaacctg
     7021 gttggatgat tattgatagt atgatgaatt taccattact gtattgggct tcgagggaaa
     7081 ctggtgatcc gaggttctct aaaattgctc ggcagcatgc agatacaaca gctaagtatc
     7141 tagtgaggaa agatggatca accgggcata tcgcagaatt tgatgcagaa tcagggaaat
     7201 atattcggtt acttggcggg caaggataca atgagaattc ttgttggagc agaggaaatg
     7261 catgggcttt atatggattc gcgttaagtt atcgttacac aaaaaatccg tactatctag
     7321 ctatagcaga aaagatagca gtaaatttta ttcagaaaat cgaaaaaact ggttatattc
     7381 ctctcattga ttttgctgta aaagattcga atattgatac cagtgctgga gtatgcgctg
     7441 catgcggtct tctggaatta gcaggatatg tttcctctgt acgatcaaaa atgtatcatg
     7501 aagctgctat caatatactc caaaagacag aaaagcacta tgcaaattgg aatatggatg
     7561 aagatgggat cattggaggc ggagcagaag cataccatag agaactgact tataatgtgc
     7621 cactgatcta ttctgattat ttttttattg aaggcttact tcgattagaa cagtcggaat
     7681 tagctatttg gtagtaaaaa gaggagaaaa tacaatgaaa catccagtac cactattaag
     7741 gaccagacag gattactttg acttatttaa aaagataaat caaccactcc agccgtttta
     7801 tcgagcaagt ggcgcacaaa ttgattatat acatcaaggg gtaggatatg gaaataaaat
     7861 tgcaggaatg gaaggattct ctcgggtttt atggggagcg gggcccgcaa ttgaccaatt
     7921 agatgaacga tggttgaaat taattctatc aggaataaaa gctggaacag atccttccca
     7981 tcccgattat tggggagaaa tacatgaaag agaccagcgt atggtagaaa tgcccgcaat
     8041 gttattagcg ttatatcatc atgaacaatt attatggaaa aaattagata caggagaaaa
     8101 aagccagatt attcattggt tctcgcaaat ttttgaatat gaatgtgcag atggtaattg
     8161 gcaatttttt aagataattg tcggaacaat tatccaaaaa tttggttatc cagttaaaga
     8221 atcagcactg aaagaagcat ttgataatat agaaaattgt tatcttcaaa atggctggta
     8281 tcgagacagt tcaagaggtc gccaagatta ttataatcct tttgcatttc attattatgg
     8341 tttgatttat agcgtactag aaccagaaaa gcccattagc cagatatata agaaccgagc
     8401 tattgatttt tctagagact atattcattt ttttgcggaa gatggtgcaa atgtgccttt
     8461 tggtcgaagc atgatttatc gttttgcagt ttcaagcttt tggtcagcta tgttgtgggc
     8521 cgatcttttg ccttttaaat taggtgaaat caaggggtta gtcaatcgga atataagatg
     8581 gtggatgcaa aaagaaatat ttgatgaaaa aggtatcctg aatattggtt atacctaccc
     8641 tcaattgaca ttgactgaac cctataatag tacgttatct ccattatggc tgaataagat
     8701 ttttttattg ttggcgctac ctgaagacca tgagtattgg acggctaaag aaatgcctat
     8761 gcctattcgt gaaggaacta aacttctttc agaagccaat ttgctcatac aacatgataa
     8821 tggacataca ttttttttga atgcgggaca attagggcca aatttccata cattgaccaa
     8881 tgaaaaatat ttaaaatttg cttattctag tcaatttggt ttttcgatac cgcgagcgaa
     8941 tcaattgaaa gcagaaatgg caatggattc aatgctaggg attcagcgag cggacacata
     9001 tatcacgacc agttttaaga atgagagcat caaaacctat ggacagttca tcgttcgaaa
     9061 taatgtacga gacattgtat gtaagaaaga ggtacttgcc tctacatggg aacctacttt
     9121 acaggcaaaa atcagaactt ggcttattcc ttttgaaggc tggcagattc gcgtacacaa
     9181 agtagaatta gatacagaat atgttctata tgagacaggg tttgctattg aatgttctcc
     9241 tgagaaagaa ggaataatca tagaagaaga caaggaaaac tatagggtga gtgaagctgg
     9301 cttttcaggt attatctgtt taagtgacga tactattaaa cgaaaatcca cagctattat
     9361 gggtttgccc aatacaaact tgatgacatg ggaaaacact tttattcctg gattagaggg
     9421 tacatttgga aaaggaaccc attggctcgg aacaggagtg gttgctcatc aagatcggga
     9481 ttatagttta gaagtatgga acaatcgtcc caaaattgat tttgatggga caaccgggct
     9541 aactatccaa aataaaaaca ataaaaaaag actaaaatta tgctaaaggc tggtggggaa
     9601 atgcttgata aagtgatgtt tgaagagata atacatccag aaaaatggat aaatgaatgt
     9661 tataaagaat taatggaaaa agaatggaat aatgagatcg agcgttgtcg cagacacacg
     9721 gagaggttaa tcaaacgtat cagtaacagt cagtatcaat tcccaagcga gtgtcctata
     9781 aaaggacgtt atccattaag agacaatatt ggttggacag aaggattttg gacaggaatt
     9841 aattggttgt tatttgagaa gacgggtgat cctttatttc aacaaacagc tgaaaaagca
     9901 gatatagatt ttatccacag gattgactgt caaattatca ctaatcatca cgatcttggt
     9961 tttttgtatt ctttatcaac cgtagcagat tataaaataa cgggaaatcg aaaaatgaag
    10021 gaagcttcaa ttgatgctgc agaaacatta cttcagcgtt tttgggagaa ggcaggagtt
    10081 atacaagctt ggggagatcc tagtgatcct tcacaacaag gtagaatgat catggattgt
    10141 tgcatgaatc ttccattatt gtattgggcg agtgaagaaa ctggaaatca aaaatataaa
    10201 aaagctgctc aggctcatat tcaaaatgca gcagattatt tagtaagaga agatggttca
    10261 acttatcata cattttatat ggatgtcaaa gatggaaaac caagatatgg aagtacgcat
    10321 caaggttata gtgataattc ctgttgggct agaggccaag catgggggat ttacggtttt
    10381 gcattaagtt atcgttattt gaaagaacaa aaatattttg atttaagcaa aatattagcc
    10441 aattatttta tgaatcggtt gccagaagat accatttgtt attgggattt gatctttgat
    10501 gattctagca gagaagaaaa agatacatct agtatggtga tcatggtttg tggattatta
    10561 gaattaatag aatcaggtct attagacaaa acagaaaaga acttatacca gtctgctgtt
    10621 tggaaaatta tgcgacaatt gaaagaaaga tatgctacaa cggaagaaga agatggcttt
    10681 ttaacacagt ctgtttataa taagcccaaa aataatgggg taaatacacc ttgtatttgg
    10741 ggtgattact attatttaga agctttagtg agaatgacta gtaattggtc ttcttattgg
    10801 tgaaaaaggt aaatatggaa tttttgtttg ataaaataaa aaaagaaaaa ccaaaacagc
    10861 atgaatggtt tctgttttgg ttttttcgtt aattttcata ttcttctaat tccaagctta
    10921 gttcttccca ttccgtcaat tttgtttctt gatcttgtct agcagcttct aaatcttggt
    10981 tcagctcatt gagttttacg tgatcttcca ggttttctgg cgcgaccatt tcttgttcca
    11041 actgatcgat ccattcatcg atccgcgcca tttcttcttc aacctgagta atttttcgtt
    11101 gaaggctacg gataagcttt tgctgttctt tgctttggta ataatcagat ttgttcgtgg
    11161 gagcaggagc agattctggc tcatcttgtg ccaacaattc ggcgatttct tcttcttcct
    11221 gctttttctc taaataataa tcatagtctc ctagatagac tttgctgcca ttttcagaga
    11281 gttcgacgac ttttgtcgcg atccgattga tgaaatatcg gtcatgggaa acaaaaagca
    11341 gtgtgccgtc ataatcgatc aatgcatttt ctaatacttc tttgttgtca atatctaaat
    11401 ggtttgttgg ttcatccaaa atcaaaaaat tttctttgtt catcgctaac ttggctaaag
    11461 caacccgtgc tttttcaccg ccacttagca gagggattgg tttttctaca tcttcgccag
    11521 aaaataagaa agcacctaaa gcacttcgga tctctttttc tggagtggta ggatgctcat
    11581 cccacaattc tgctaggatc gtcttgtttg tatgcagatc agcttgacct tgatcgtaat
    11641 agccgatggt gacatttgtc cctagcgttt cttttccacg gataaaaggg atctggtgaa
    11701 tgattgattt cagcaacgtc gatttcccga taccattcgg acctactaga gcaatcgctt
    11761 cttgacgacg gatatctaga ttgattggtt cagataaggt gacattatca tatccgatag
    11821 cggcatcttc gatttgcaag actacatttc cagaaggctt ttctatactg aatagaaagt
    11881 ttgcttgttt ttcatcccct tgaggacgat ccagccggtc cattttttct aatgtctttc
    11941 tgcggctttg cgctcgtttt gtggtagagg cgcgaacaag gttccgagca acgaagtctt
    12001 ctaatttatg gatttctgtt tgctgctttt cataagcctt ccattcactt gctaactgtt
    12061 ctgctttcaa atctagatat ttcgaatagt tacctttgta atggcgcatt tttcttctgc
    12121 ttaattcata gacttcattg actactttat ctaaaaaata acggtcatgg gaaacaatca
    12181 ataatgcacc agtatagctt tgcagataat tctcaagcca ggaaagtgtc tcgatatcta
    12241 aatggttcgt tggttcatct agaatcaaaa tgtcagggtg ttgcaaaagc atgcgagcta
    12301 aagctaaacg tgtgcgctgt ccgcctgata aagtatcgat tttctgatca taaaatgaag
    12361 aatcgaattt aaacccatgc aatacggaac gaatttcatt ttcataacca tagccgtttc
    12421 gatctgaaaa atcgtgttgc agccggtcgt attcttttaa ataagaacta taagcaggtg
    12481 tgtctggcgt accttcgcta atgaaaatct ctagctcgcg catccgctct tccatttgtc
    12541 taacttgttc aaaagctttc agcatctcgt tccaaactgt ttcattggaa tcaagtcctg
    12601 tgtcctgagc gaggtatccg agagtcgctg ttttattttt agcgatcttt ccttcatcag
    12661 gtgcttcaat tccagcaatg atctttaata aagtcgattt tccagcgcca tttctgccaa
    12721 ctaaagcgac acgagcgcct gtactgattt ctaaatgtat gttttcaaat aagacttctg
    12781 caccaaaatg gcgagcaatc tgattggctt gtaataatat catggaatcc tcttttctac
    12841 tttgtgaatt ctcctcaaat aaaaaactat ttttcaatta gtagtctacc ataaattcca
    12901 ttatactgcg agatttgcag aaatgataaa taaatgaata aagaataaaa tttcacaata
    12961 tctgagcaat ggaattgatt ttttcctata aatactgcta tgatggagaa atcaaagatg
    13021 taattagaca atacgtggag gtcatttcgt gaaagatcat attattccaa aggcgacagc
    13081 taaaagactg cctttgtatt atcgctattt aaggatttta aataatgctg gaaagaaaaa
    13141 agtgtcttca actgaattaa gtgaagccgt tcaagtagat agtgcaacga tccgtcgaga
    13201 tttttcttat tttggcgaat taggaaaacg tgggtatggt tatgatgtag aagatcttat
    13261 gcactttttt gcaaagacat taaacgacga tcaattgaca aatgttgcgc tgatcggtgt
    13321 agggaacttg ggaagtgctt tactaaaata caaattccat caaagtaata gcatacgtat
    13381 cagttgtgct tttgatgtga atgaggaaat cgttgggcgc atcgtagatg gtatccccgt
    13441 ttatccaatg gaagatatgt cagaacaaat caagatccaa caaatcgaag tagcaatttt
    13501 aacgataccc gctgaaagag cacaagaagt agtcaatcag ttaacggaag caggaatcaa
    13561 aggaatcttg aactttaccg ctgctcgatt gaatgctccg tcagatgtat tgatccaaaa
    13621 tgttgatttg acgaatgaat tgcaaacctt gatctatttc ttgcattctg acgcaaatgc
    13681 gcattccgaa aatacagcag aataaaaata aaaagcgatt gaacaaatga aggcaaaact
    13741 ttcacttgtt caatcgcttt tttctgtttg gacaacgatt attttgttcg gaagatttct
    13801 tcataagaaa gggaatcatc ttctgctgtc agttcatcta gtagataacg gattttttta
    13861 aagtcgatga accgtgcttg ccgaaagact tcttttcctt gatgaaaaat caggacaact
    13921 ggcgcagtca gcacttcaaa tttactagct acttctggtg tttcaaatgc atccaaatga
    13981 agtgccggaa tatcataatg tgtgagaagt tcctctagtc gtggacgaac agcgtgacaa
    14041 acactgcaat taggcatcga aagataaatg acggcaacgg atgactgttg cagtatgtct
    14101 tgaacttcag tcaagttagt ggtttgtttc atttttattc tcccttttat gatagaagtg
    14161 atatgtatga gaccttaatt taatgggaat aacagaaaaa gtcaattgaa gtgctttggt
    14221 aaaaaataag agttgtgtaa aaatttacag agcaacttgt tttttttgaa taaaagcgta
    14281 tatttgcaaa gcgaatgaac tagaaataaa aaggaggaaa ctcatgtttt cttttattcc
    14341 aaattcggtt ttgcagatga gtacgatttt cttatcgatc gttattgaag cattaccttt
    14401 cgtattatta ggctgtctta tctcaggcgc cttacaagta tttttgaccc cagaacgtgt
    14461 gaagagatgg cttcctgaaa atcgtatctt ctctattttt actggttcga tcttaggatt
    14521 tttctttcct tcatgtgaat gcggcatcgt accgatcgtt catcaatttg ttaaaaaagg
    14581 cgtaccagtt cacacagcgt ttgcttttat gctgactgct ccgatcatca atccaatcgt
    14641 gattttttcc acttttatcg catttggcaa ttcttggcag atggcaagct ggcgggtgat
    14701 aggcagcttt tttgttgccc ttgtgattgg tgtctggctt gcctattttc aaaaagacgc
    14761 tgtattgaaa gaaaaaatca cgtctaaagt agcagaaaat caccatcatc atgtccatga
    14821 agaagaacaa agtgagaaga atgaaccaaa aaatcagctg atccatcaaa ctgggcatgt
    14881 gttgacacat tcaatcgacg aattttttga tacaggtcgt tatttgatca ttggcggatt
    14941 aatcgcagct gcgatgcaga cttatttacc aactagaatt atgctaacgc tcggctcaac
    15001 aaagatttta gccattatca tcatgctgtt attggccttt acgatgtctc tttgctcaga
    15061 agcagatgcg tttataggat cttctttgtt aagtctgttc ggcacagcac ctgtagctgc
    15121 ctttttggtc tttggcccaa tggtcgatat caaaaatcta ctgatgatga aacgatattt
    15181 tacaggacgc tttattttat cgctgatcgg actgattgcc cttagcgtta ttggattcac
    15241 attatttatt taggagggaa aatatgctgc ggtttttgat tttatctggg tatttcgaat
    15301 tgatgatgta cttgcaagtt tctggcaaac tcgatcaata tatcaatgtc cattatcgct
    15361 acttagctat tctttcaatg attttatctg ctcttttggc tttagttcag ctgtatttgt
    15421 gggtcaaaaa cggaaaagca gaagaaaagg cacacgagca cgatcatgac catgggttgt
    15481 caaaacctta tcaacgtgga atcgcttatg tactgctagc tttgccagta atcgtgggga
    15541 cgttgtttcc aacagttagt ctcgacacta cgatcgtaga agccaaagga tttaatttcc
    15601 cagtaagtaa agaatcagta ggggatccgg agatgcagac acaatactta aagccggata
    15661 ccagtattta tttcaacaaa tcagactact tagaccaaat gaatgagttg aaagaaaagt
    15721 atggggataa gcaaactatc aagatcacag atgaaaacta tttagaagtt atggagctaa
    15781 tttataatta ccctagcgaa ttcattggca aaaaaatcag ctatgaagga tttgtttacc
    15841 aaacaccgaa cgatagcaat acagatatct tcttgttccg attcggcatt atccattgtg
    15901 tggcagattc aggagtcttt ggtttgttga cgcatatgcc ggaaggagta acggttaaaa
    15961 atgatgaatg gtataaaata gaaggaacca tccaatcaga ctattatcaa ccattcaagc
    16021 gtgaaatccc atctgtagtt gttacaaacg ctgagaaagt ctctgctccg aaaaatcagt
    16081 atgtgtatcg ttctttttaa aagaacaaaa taaataaaca tagctcagac agctgacacg
    16141 caaggacgtc ggttgtctgg ctttttttgc atgatgtatt catttgtttg atatttattt
    16201 tagaagcagc atcctgaaag tatttgatat cggtttcaaa ggtgttggaa aagattgtga
    16261 agagaattac aatttattcc taacatgtat gttgaaaagt tgtatgaaat gattttgata
    16321 gtaaaatatc gagtggaggt actttttatg gtaacgcgta tatttatttt ggatgatagt
    16381 ttggtttttg aaaaaatgct agtagaaatt ttggaagaat ccagaatttt attaagtcct
    16441 tggaaatttg agatcgttca gggattgaac gttatacaat ttgttgaatt cattaaaaat
    16501 aatgaaatct attcctcaga tatttttttc ctagacatcg atttgaacgc ctattatagc
    16561 ggtatcgaac taggcgaaat gcttagagaa aagaatgaaa agtgtaaaat tgtttatcta
    16621 acgtctcatc cgaataaagc aataactgtt attaatcgaa agattacgcc tagtggttat
    16681 ttgataaaag aattcactta tgaaaaaaat aaaaaaagca tccaaagtta cttattgaaa
    16741 gaaaaagaaa actatcctgt tcaacatgct acgaaaaaaa ggtggacaac tgtccgttat
    16801 ggtaatagcg atcactatat ccattacgat gaaatccttt atctaatgag catgccaggt
    16861 tataaaaata aaataggcct agtattgaaa gatgaagaga ttctcgtaaa cggcacaatt
    16921 aaaaaatata aaaaatcact cgaatatgag tatttatgta aagatttaaa agcttatatc
    16981 attaatactg aaaacattac atctattagc agagtaaacg aaatagtaac atttgcaaat
    17041 ggagaacaac tagagatggg aaagagaagt attgataaac taaagaattt tatgcaagaa
    17101 aagatagaaa atgaatcatt ttaaagaaaa caaagactca tatcttacct gttagaagag
    17161 tgttttcctg tagaagagaa caacccaagt agcagcctag tcgtttctat ccttttttgt
    17221 tatgcactct ttttgacatt tactccacca ataacgaagg gtacaataaa aagtaataac
    17281 aaacaaaagg agtacagaaa tgattgaatt catcaatgta agtaaaagtt acgggaaaaa
    17341 acaagcatta aaagacttgt ctctctcgat aagacaaggg gaaatttttg gatttttagg
    17401 acataatggt gccggaaaat caactacgat taaaagttta gttagtatta ttgaaccatc
    17461 atcgggaacg attttagtag atggaatgaa attgacggaa aatcgattga gtatcaaaca
    17521 aaaaatcggt tatgtgcctg attccccaga tattttttta caattgacgg ctggagaata
    17581 ttgggacttg atttcagctg cctatgaatt agacacacaa aaaaaagaaa agcgtttagc
    17641 agaattgaca gcgctttttg atatgtatag tcatcaaaat gaaacaatcg caagtttttc
    17701 acatggaatg cgtcaaaaaa cgattttgat cggcacgttg ctgccagatc cagatatttg
    17761 ggtattggat gaacctttgc aaggacttga tcctcaagca gcatttgatt tgaaagaaat
    17821 gatgaaggct catgccgcaa aaggaaaaac agtcattttt tctacacatg tattggatac
    17881 cgcacaacag ttatgcgata aactggctat tttgaagaaa ggtgaattga tttatcaggg
    17941 ggcagttagt gaattattga atggctcacc tgatgaaacg ctagaaaaga tttatttgaa
    18001 aatggctgga aggcaagcga caggagatgg accgtatgta taagcgacaa ttattagaat
    18061 taattcgagt taatctttta tatgttaatc cacagctcac gaataaagca agagagaaag
    18121 gaaaaaaggg aaagcgatta actatctatc ttttgtctca aaatcttttt tcagggctga
    18181 tttttttact gatttacgga tttgctatgt ttgctatgaa ctttgttaaa ttgccaggtt
    18241 tctttactta ttacgtggca ctttttggta tgttaggttt aactcaaagt atatcagtca
    18301 tttataatat cttttttgaa ggaaatgacc tgcaagtatt tttgcctctg ccttttggac
    18361 aagaacaggt tttttcagca aagattttgg tagttgcttt gaccatcatt ccttttgttt
    18421 ttccgcttct agtcatgttt attttaaccg gatggcgagc tgatctaggg attttgctta
    18481 ctatcattat ctcaatcctt ttgttttctc tatttttgat tattcttttt tgtctggcta
    18541 gtttgattgt ttttggtttg gctcgaacag cagtgtttaa aaaacataga aaaacagttt
    18601 ctagtatctt gcttggcagc tcgatgctga tcgcatttgc tggaatcatg tggatgaatc
    18661 atcaaacggg gactattgaa aatgagttaa cagatcggca tccgatttcg atattattgc
    18721 cattctatga tgctgccagt cagccacttt ctcaacaagg tttattgggt tggggaatac
    18781 tagctatcac ggctctggga tttttccttg ctgtaaaaca gctgatagta ccaaagctta
    18841 cagagcaact gactgattca aacagtgagt tcaaaataaa aagaacccat aaaaagaacc
    18901 aaaatgtgca tcagctttta tttagttaca atgctcaatt agtaaaagaa cctaatttga
    18961 ttatgcaagt tctttcttct tccttgttaa ctccaatcat ttttattctt gcttttgccc
    19021 taggaggcga aataaaatta actgatttag ataataagtt aatcggtgtt gttttcctgg
    19081 tagggatcgc attggctttc ttaacagtta atcagacttc ttttatcagc aatcttattt
    19141 ctttggatca agaaaatttt ctgtttatcc gttctttgcc aatctctatg aaccaatatt
    19201 taaaagaaaa gttcagattc ggatggatat tgcagagttt tttaactggt gggatcgcat
    19261 tattaagcgg actgtctttt cagctgcctt tgttttttat ccctagcttg ctatttggtt
    19321 ctttattcgg ctgctactta ttgtcactac gttatttcgc tagagattat cggttgctgc
    19381 tgctgaactg gaccaatatt aaccaattat ttaacagagg ttcaggaagt ttgggtttag
    19441 tcgcaactat gatgggttca ttgatcatca gtattattct tatcgtctta tacggaatgt
    19501 tggctttgtt ttatccattt tggttagtga atattcctgt gatcggttta gttctaatac
    19561 tttccgctct atggatcgtt tattatcaac gaacgttttg gaaaaaattt gaataaagaa
    19621 gaggggccgt gacaaaaatc atgtcgcagc ccctttttta cagatagagg gtgttcaaaa
    19681 gtcagtttct cagtattaag tcaattttat gtaaaaatgt gagaagctat ttttacaaaa
    19741 ctttttttaa tactcataat tacttcttat tgctcctgcg gttacttgtc gcaatgtttg
    19801 tgagatattt tgtcatcgct caaggctgaa cgtctctttc acaacctttt ctttgttaca
    19861 cttcgtttat ttaaaaagcc gtttttttcg tttcatcatg attgcgtcac gctttacttt
    19921 gaaattacgg atgttatggt taaagacttc tgataataca agacctaaag cgattgctcc
    19981 agcaatcata attgcttgga ccgcataatg agccgcttct cgataggatt cagtaacgag
    20041 atttcgaacc gcttgataag ctaaaccacc agggactaga ggaaccatcc cgggaatatt
    20101 gaaaatcgtt acgggcattt tcaaacgttt agagaaaaga tcgctgatga atgctactcc
    20161 taaagaacca agcaatgaac caaaagcagc agatccgcct atttgaacac agatccagta
    20221 gatcatccag ccaaaagcac cagaaagacc acaacaaatc aatgaacgcc taggtacatt
    20281 tgtaataacg gcaaatgccg cagtcgctaa aaaactaaaa gaaaactgaa taaatatcgt
    20341 ccccatactt gtgttccttt cctaataaaa aagctggaaa ataaaagcaa tcgcaaaacc
    20401 gatcatcgta gcagtcatca tcgcttctgt tccgcgagaa actcctgaga cataatgtcc
    20461 agctagcaaa tcacggatag cgttcgtaat ttgaactcca ggaactaaag gcatcacaca
    20521 tccgataatg attagatcct gattgcttcc taagccaaaa cgtacgctgt agatagcggc
    20581 tatgccaatc aataaagaag ataaaaattc cgataaaaat ttgattctaa aaaatttcaa
    20641 actatataga taagctgcgt atcccaatcc tccaatgact aaagtcacag gtaaatcggt
    20701 catctttccg ccaaataaca ccataattgt tccactgatc actgccgcgc taacgatttg
    20761 caaccagaca ggaaagaaag aacggtctcg gtcgattgct tgcagttcgc agtaaagttc
    20821 ttctaatgtt agctctgaag caacatattt acgtgaaaga tcatttactt ttactacttt
    20881 ttctaaatta atcgaacggt tggtaatttg ttccattcgg atggtcgagg tacgatcaag
    20941 accaataaag agaccggttt gagtgacata gctgaccaaa cggaaatttc cagaagctaa
    21001 agcaattcga ctcatcgtat cttctacccg atacatctcc gcattgcttt ccatcatgat
    21061 tttcccagcg agtaaacaag tgtccagcaa cagatctaat tcttttcccg tcatagcatc
    21121 ttctccaata attgattgat tagttttatt ttactacaaa acataccaga agcgtaaaga
    21181 ataaaaaaac ttgaggaagg aataaaagag gcgtatactg tttttgtatt gcgggtgtag
    21241 tttagtggta aaatcccagc ttcccaagct gatgtcgcgg gttcgattcc cgtcacccgc
    21301 ttaaaatagg ttgtgaaaaa gctgctctgc aacaagtaat aagaacagcc aagcaaaaac
    21361 aacttcttat gtttttaact tggatggact tattaccgca gatgcaagct tttgcgcacc
    21421 gtttaccaag cggttgtgaa atcagtgtat tgtcttgagt atgaagaaaa tttttgaata
    21481 ataataaata ccttacagat agagtggtga ctgattagag acgaggaatc cgtctctttt
    21541 ttgtattttt aagccatctt aaaacaggtt ttattttttg ctgtttctat ttctttctag
    21601 tatttattta taggggaaca tatgttaaga tttagggagc tgttagtaaa ggagtaaaga
    21661 aatgagcaaa aaaacaacca aggcgatcgt ggggatcgtc gctgctgtga ttgcaggggc
    21721 attcggtgtt tccaccacac aaaaagattc agatatcttt cagcagatta caactatttt
    21781 tgattccaca ccacaagctt ctcaagtagc ggatgtgcca gaatatgatg gaaaacatca
    21841 agaaatagaa atcaatggga atcagccgga atttacaaaa gaggatctta gcctttccaa
    21901 aggaacatgg gaaagctatt caaatattga taaattgaac agagtaggac aagccaatgc
    21961 tatgcttgga aaagatttgt tccctactga aaagagagag cctttgtata ttgacccgac
    22021 aggttggaaa caaaagaaat taagtgacgg gcaatggtta tataatcgca gccatttaat
    22081 tggtttccag ctgactggtc aaaataacaa cattaaaaac ttgatgacag ggacacgttc
    22141 gttgaatgct ccatacatgc ttgctcacga aaatgatatt gcggcatata tcaaagaaac
    22201 aaatcatcat gtacgctacc gtgtcactcc tcattttgag gggaatgaac tggtagccag
    22261 gggagtgcaa ttggaagcag aaagcattga agacaaaaaa attgaattca atgtctttat
    22321 ctacaatgtt caagatggct acacgatcaa ttatgagaca ggacaagcaa caaaaacaaa
    22381 aaattagtag cagctattcg aattttttat gaatattatg aaaaaattgt gtaaaaacat
    22441 acattcaaag aaatatagcg tatactttat gaaaagagta cttttgataa agctacagaa
    22501 aaaaggaaaa aaacatacaa atagtgtttc ttaatttatt cggaagtttg gaatatttgt
    22561 ttgtagtttt ccctttcttc gagtaaaata aggttgtaga aggtaagctg gaattacctt
    22621 gcgggaaaga ggtgtagaat catgggtttt acagatgaaa ccgtacgttt tggttttgac
    22681 gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg tttatcgggc tttggaagaa
    22741 aaaggctaca atccaatcaa tcagattgtc ggctacttgc tttctggaga cccgtcctac
    22801 attcctcgtt atcgtgatgc tcgaaatttg attcgccgtc acgaacgcga tgagatcatg
    22861 gaagtaattg tcaaggacta cctctcaaat catggagtga atttatgaga gtaatgggct
    22921 tggatgtcgg ttctaagaca gtaggtgttg ctatcagtga cccctttggc tggacagctc
    22981 aaggagtaga gatcattcgg atcaatgaag cagaagaaga gtttggcttt gatcggttga
    23041 aggaattagt agcacaatat gaagtagacc ggtttgtagt tggattacct aaaaatatga
    23101 acaattccat cggaccaagg gcagaagctt ccatgtcata cggagaaaag atcaaagaac
    23161 tattctcctt gccagttgat tatcaagatg aacgattaac cactgttcag gcagaacgta
    23221 tgctagtaga gcaggcaaat acttcaagag ccaaacgaaa aaaagtcatc gataaattag
    23281 cagctgtgat gatcttacaa aattatttag acggctcagg taagcaatta ttttaataat
    23341 aaaagaaaag aggtaatctt atgacagaac ataaccattc ccacgaccat gaaggacacg
    23401 aacacatcac attggtggat gaccaaggaa atgaaacatt atatgaaatc ctactaacag
    23461 ttgacggaca agaagaattt ggacgtaact atgttctttt atatcctgct ggtgtttcag
    23521 aagatgaaga tgtagaatta caagcttatg catacatcga aaacgaagat ggaacagaag
    23581 gcgagttaga acaaatcgaa acagacgcag aatgggacat gattgaagaa gtattcaata
    23641 cattcatggc ggaagaagaa gaatagacta taaagctagg agaaaccttg atatgatagg
    23701 gtttctcctt tttttatttt ttactgtatg ccatattgta tgccatctag tcaatattta
    23761 agtgttgtac taatttttca acagtctttt ctttcgtttc ttttgccaag tgaccgtaac
    23821 aatcgatcgt ctgactaatt tttgtatgcc gtaatctagt ttgaacttct accatagtag
    23881 ctccagcgtc caagagcatt gaagcatgag tgtgtcttgc tacatgcaca ccgagaaatg
    23941 gaaccatagc tttttcacaa atagtaatca atcttgcata aatagcgtgg tgtgtgatta
    24001 gttctttata gataccacaa aaaatcatag tcggatcagt tacaccaagt gtcagcatat
    24061 atttccgctg attaatctgc cattttttta atatagaaat tgttctttca tctagtggaa
    24121 gaaccccagc actacaatca gttttaggat cactgatttt atagccattt ttggattggc
    24181 ttagtgtttt attgatggtg accgtatttt cttgaaaatc aatgtctgac caattcaatg
    24241 caagggcttc actgatccta accccgctat aaaagagaaa gcgtagtaac gttttatcaa
    24301 agtcgtttcg ataagtttca ggtttgctgt ttaggtaatc aaacaaggtg atcagttgtt
    24361 ctttactgta aactttgacc ttttctttat gcttagtggt ggttctttta ggcattaata
    24421 cgttgtctag tggattagtc tcaataatcc caagattgat agcgtagcta aaaatacgct
    24481 tagaagttga atgaagtacc ttgtattggt cagtagtttc agcccagcta tttacaattt
    24541 gttgggcttt ttttaccgtg acttcattca cacgaagatt tccatatttt ggaagaatcc
    24601 actttctaaa cttgatttca gttttcatga aggtggcttc tcggacagtg gttttatatg
    24661 tttctagcca caagtcataa acttctttaa acgtttcgtt gttcgctttt ttaataccgt
    24721 ttttatcgta gtccacttgc aagcgtgaca aggcaagctg ggcttctttt tttgttttgt
    24781 aacctcgtct acgaacctta tcaggtttgc cagtcatttt gttcattcca agataggctt
    24841 catagagcca aaatttacct tttttagttt catattgctt gaatgttgcc ataatagttt
    24901 tccctccata gtgtagcaag ccgtgggggc ggttggagga ggcagtttat tattattttg
    24961 aatagtgttt atttagctca gtaacaagag ctgtgaactc ttttagaaga tcattttcat
    25021 aaaattcttg atactctttt ttctcatctg tatttttttc tgaatcatta attaatgagt
    25081 catatcgtaa aagcgtattt agaagagctg cgagataagc aattggggta ctcccgtcag
    25141 gaaattcaat tcgagatcct gttttaagat attttattgc gtttgttaaa taaatcttct
    25201 gtgagacagt caggttatct tcttcgatgt tattgatagc attagaaaga ttagaatcaa
    25261 ttatagagtt atttttttca atagtttttt tcaattgctt ttcaagcaca tttcgcttaa
    25321 tttcgggcat catatgcata tctcttaatg tataagatcc gtttaataga taggtagtgg
    25381 atacatctaa tacctttgaa agttgtttaa gcctggtgtt attgggaaga ttatagccat
    25441 tttcccaatt actaacggca cctttactgg ccggtgggga taatttacct ccaagttgtt
    25501 ccattgagag tcccttttca attctagcca gtctaattct ttgtcctgtc tccactgctt
    25561 cggggtattt ttttctagcc acattttcac caccattcat atattttctc tactatatca
    25621 cgatttaaat atgtgtgaaa cataaaagtt caaaaaagta tgttaaaatt cttgcaaatg
    25681 aaaaggtatg atggtatatt gagtttataa gaggtataga aatgtattca agagcctctt
    25741 gcattttttt aaaatctttg tatagaaatg tatgctaacg agggggggat aaatatggaa
    25801 ttaaaaattg acaaactcac gcttgatgat ccagctttta aaattattga cgatcgagtt
    25861 gttcaacaag tagagcaaac tcaaggaacg ttactttcat tattagaaaa aaagtaccag
    25921 tttccaaaat atatgaacaa ggcacaagct gctaagtata tgaacgtttc atacaatact
    25981 atgatgcaga aatatgttcc taacggttta aagttgatta tagttgatgg agtcgtaaga
    26041 atttcacaag atgaatgtga tcgctttatg gaagaatacc aaaaataaac gcaagccgtg
    26101 ggggcaaagg gattaatagg aggaaataat aatggaatcg acacaaaata aagcaatcga
    26161 aaaagtatta tcaacaattc ttacagaaga cacagcggca gaattagcaa acttggaagg
    26221 caaagcgcta gaagaaacgt ttgaatgttt gtacgaacaa atggactatc aaaaattgct
    26281 accacaagaa ccaacggtaa gcggagtatt gcgtggcttg aacgatttag tacaagcaga
    26341 gtttaaagaa cgactttcta ttgaagagta tcaagaaatt ttgtatcagc aagttgagtt
    26401 gttagcgagc ttgctagggc ttgaactgga ggacgttgaa tgaaaactga aatttggaac
    26461 ggacacatta taagatttgt cgatattaat gatgaatggt gggcagtggc gaaagatgtt
    26521 gcggaagcgt taggtcttaa acaggttact agagccattc actctttgcc taaagatggg
    26581 gttactacta gtaaggtcat cgattcattg ggcagaacac aagatgtaaa catcatcaac
    26641 gaaaaaaaat atttaccgca tggcattcaa aagccgtaaa aaagaagccg aggcatttca
    26701 agactggatt ttcgacatca tcaaagaact acgccagtcc acaggacttg aaggctttca
    26761 agtattccgc atgctagaca aagaacacca aaaagaagca atgactaaat taagccacgc
    26821 tattactgaa ccaaaaccag tagactacat taaagcgaat gtgatagcca ataaagctgt
    26881 atcaactatt tatggtcatt ccaaaatggt aaaaaagaaa gatatgactc ctgaaatgtt
    26941 ggttgatcgt gaacctattt tagatgagac agtagaatta atgactgtta aagaaaaata
    27001 tgggttgcag ttttcagtga gtgagaaaat ttataatcgt tctgctgaat tgcagacaac
    27061 ttaggagcat taacatgatc gagaacaaag aaaaagcctt atccataaca gtcttggcgg
    27121 acaggataaa ggcaacttaa ttgggataaa acccgatatt ctttgttccg attataccat
    27181 attaaaaaat cggagggaac cattatgaaa cgaaacttaa ttataggaag cattttaatc
    27241 ggcggaattt tcggcttatt accattaatt gcaaaaatag ctatctttgc aggattagcg
    27301 ttatatctct tcactgctta tgacgagtac gactatcaat taagaactgg agggcataag
    27361 tagatgtaca aaacaaaact attaaaccaa ctcgatagcc ttgaattaga ggaaattaat
    27421 caagggatcg ctgaactaga aaataatatc gggaaaacct actttggaaa ttcattcaat
    27481 gaaaaactaa cagttttgta tgtactcaaa aaacatgcag aacacaaaat aatttgtcga
    27541 gaaatcaacg agctaaaaaa tcagatttta accgcatggt taaacattac tgatatgcaa
    27601 gaagcaaggg tgaaaacatt taatacatgg gtaaagtatc agaatcaatt aaaaggtgct
    27661 gaatttgttc gggatgggtt gaaatacgaa cttgagcagt tgaagctcat ggaggtgtct
    27721 gaatgattta taccagtatt ttgaaaaagg aggagaggtt tattggcaaa taattatcaa
    27781 gcagcaacgg aattacaaaa gtcgggatgg tcaatttatc ccttatctcc tggaactaaa
    27841 attccaataa aaggctctag tggttggaat gatgcaacta acgattctaa tcaaattaat
    27901 gaatggtgga cggaagatgc aactagaaat attgggttaa tgcttgaaga tcatcaaatg
    27961 gtggtagttg acctagatca acattctgaa acacgaaacg gcgttgagaa ttataaaaaa
    28021 cttgcttcaa tgtatgatcc atttccttct acttatacgg aaatcacacc aggtaaagga
    28081 atccatttct tctttaaaat tcctgatggt gtaattatcc aacaagaaac aggtgcattt
    28141 gctgatatct tcgggcgtga tgataaaggt aaaagtttaa gcgggattga tattatcact
    28201 aaaggagttc caatagcgcc aactatgatt atttcaagaa gtgttgggag agcatatgaa
    28261 cctattgaaa acgtatctct aaataatatt gcaccagctc ccgattggct agtgaaccta
    28321 ctgctaaaaa aaccgcaaga aataaagact caataccgac ccgtagcaaa aacagggaca
    28381 gcaaaaaaat tagatatgat tgttcaaggc gctggcgaag gtagtagaaa cgatcattta
    28441 actaagttat gcggttggtt actatggcac ggtgtagata atcaaacttt agcagaattg
    28501 atttatacag caaatgcgta caatgaacca ccgctaaaag ataaagaagt gaatcaaatt
    28561 attcgatcga tgattaaaaa agatttgagg gggaaagctc atggctcata agcataaatt
    28621 agatagtatt ttagactttc ccgaagccag cgagcgtgaa gacaatatca ttgaattgaa
    28681 aacctggatg tcacgattaa gatgcaataa agacgatcag attaaaagta acagtgttgt
    28741 gaatgcagaa ttgattttaa ccaatgatag caatttagct ggaacaattg cttataacga
    28801 atttagcgga tacattcacc tattaaaaga ttctccttgg atcaatcgta ccgctggaga
    28861 atgggaagac agttttgagg atgccttaac ggcatatatt gaagaaaact acaatgtagt
    28921 ttttgatgac aacaaaatac acaaagcagt agtaaatgtg gctagaaaga atgttttcaa
    28981 cccagtaaaa gaacgtatcg aaaaagttaa atgggatcaa cagcctagac tggaaacact
    29041 gtttattgac cttttagggg tagacgacaa cctttacaca cgagaagtaa caaaacgttg
    29101 gatagtcgga tcagtcgcac gtatctataa accaggaata aagtttgaga tcgttccagt
    29161 tttggatgga ccgcaaggga ttggtaagag taccgttcca gcattacttt acacggatga
    29221 ttttttcacc gattcattag attcgctagg tgaaaagaaa gatgattata tgcagcttca
    29281 aggcaatgta attattgaac ttggagaatt atcttcaatg aacaaaacta aaattgaaca
    29341 gataaaaaac ttcatcagtg ccaagatcga taaaattaga cctccttatg gtcggaatgt
    29401 catagcttgg gcaaggcaat gtgtatttat tggaacgtcg aatgatgggc agtatttgaa
    29461 agatgataca ggaaaccgcc gtttttatcc tttgccttgt aagaataagc caaagatgaa
    29521 tccgtttaaa acaaaggatg aatattttct tcaagtgtta gctgaagcaa aggtgctttt
    29581 tgataaagga caacgaatct attttagtcc cgatgaagat aaagaagtct tagaaattgc
    29641 aaaagactat caagaggatg ccaagatgga gaatccaatt aaagaagcaa tcactaaata
    29701 tttggaaatg gaaatcccgt ataaatggga agaagctcca gcgtgggcga gacgttctta
    29761 ttatcagaac tatcctgaca gtaaatgtaa tgagaaaaat ttacagcatt tctataatgg
    29821 agctactatg caacaagagt tttatttagt tgatagcgta ctcaccgctg atattttgga
    29881 agctgttttt gataaacaag caaaggattt attgaatggt cgatcagatg cagaaactaa
    29941 aaagattgcc ttgattatta gcagtattcc tggttgggaa cggaagcaac tgccaaaaag
    30001 aaataaacga cgaggatttt acaataagtc aaatgcctat gaaaataaaa atcgagctgg
    30061 aaagtacaaa aagtaacggg tagtaacggg tcagtaacac ctagcccgtt actagtttac
    30121 ccttactgcc ccaagggata cagcaatttg gtaacggggt aacaccttat ttccttaaaa
    30181 cttttgaaat agttagctaa tatgctgggg aataatgtta ctggatttta cccgttacct
    30241 gttaccaaaa cgctagaacc cttgtccccg ttgggattga gtggtaacgg gtacctgtta
    30301 cgtaggtgtt accacgtgtt acgaatcaag gaggaaagta aatgctcaat attatttcaa
    30361 caaacaaagc accgaacttt caatatacag atgaaatgga tcggtttcta atgaacacgc
    30421 tggcatttag tgtgggattg gtaacagaag attattccac atttgatcca gaagtattaa
    30481 agataatgga agaagaacct gattggctgc aggagtcagt agcgtggtgt caatcgctag
    30541 tagtgggatc attggtagat agtggcaact atgatgatac aggtgagcta atggatgaat
    30601 ttaattgtct gcttaaccta tatgatcgag cgagacaacg agagcttaca tcgaatgagg
    30661 ataatttgtt tttaaacatc catgataagt tcttggcttt gctactaaca gatgatgaat
    30721 tgataactaa tttattggag gtagaataat tatgcatatg gaaagtatta gatacttcga
    30781 tggtgagaaa cacattgagt attcaaacac tcaagaagat gtagacttta ttagttttga
    30841 ggaagataaa atcactaaag ttaattttaa agacggaacg tgcttgaaga tagtttcgcc
    30901 ttatattgaa tacaaatcaa aatgggaaca agatgattct gacgaacgag atcgctttgg
    30961 ttggtaatct atggcagtta aaaaacaatg taatcatgct ggatgtaaaa cattgattga
    31021 ttataggcag aagtattgtg ggaagcataa agcaaagcaa acggcaatta agcgtgaaga
    31081 aagaaagcaa agcgaaggta aatattttca attctatcaa agtagaacat ggcgaaaggc
    31141 ttcatacttg tatcggttaa atcatccagt atgtgaggat tgcctagaag aaggcttgat
    31201 aaggaaagct gatgttgtag atcacaaaat tgaactaaaa gatgattgga atagacggtt
    31261 agatgaaact aattttcgtt ctttatgcca tgcacaccat aattccaaga cagccaatga
    31321 aagacaaaga cgagaaaaga gtaccctttg agttaagggg gcatagtgtg aaacttactg
    31381 acaatcgatg cctactcatt ttggtacaaa taaccgttgt gaaaaggcat aagggtaatt
    31441 acaaataacg attacacttg taatcacaag tgaaaaagta tataatgaaa gtaggagatt
    31501 tattgaaaaa tacaattgtt attactgata aaacagggaa acagcgcacc attgagttac
    31561 ctcattttgg tcaagtgacc attcaaatgc agaacggaaa aatcatttat atagataaat
    31621 tagataaaga aaaattctga tcgaaaaacg aaggaatgtg agcttaattg cttacgttcc
    31681 tttttctttt gtctgaaagg aggacaacat gggacaccct aaaatattac acgatacaaa
    31741 aggcaatata tcaagtgaag aaaaagcaat ccgtgtggac gctagagaag aattgttcaa
    31801 gcagcaacca ttaataaata tcacgccccc tgactggatg gcagcgagcg ctagaagtga
    31861 atggaatcgt atcgtaccaa cattaaaaaa agattatcca ttgagtgaag cagattatgg
    31921 ttcattggta gcctattgtt tagcctttgc tcgaatgaaa acagccgaag ccgagataag
    31981 aaaatcaggt acgtttatca catgcgaaaa cggagtaaag aaagccaatc cagcggttcg
    32041 ggttcaatca caagctatga gtgatttgaa aaaacaagcc acctcactag gtatgacctt
    32101 agaatcacga tcaaaactag ctttgaacaa ggttaaaaat gatgaacccg aagacccgtt
    32161 caaagagttg atgaattcat gaatgattac attgagaaag tcctatcagg taagctgatt
    32221 gcacccaaga aaattatcca agcgtgtgag cgtcatataa gcgatttgga gcgttctaag
    32281 tcagatagct tcccttatgt gttcgatgaa gaacaagcca ccaaagcgat taaattcatt
    32341 gagttgctac catctacgga cggtaaagca atcaagatgt taggatttca aaaattcatt
    32401 ctaggcagtc tttatggctg gcgtactaaa gaagggaatt acaggcgatt caatcgagcg
    32461 tttaccagta tgagccgtaa gaatgggaaa acgtatatcg caagtggcat ggctgccaat
    32521 gcgttgatta tggaacaaga accagcagaa gcaaggcaag tattgtttgt aagtaacgct
    32581 ttgaaacaag ctaaattggg ctatgatatg ctgtctaatt cacttagaaa cgtggtcaag
    32641 tctagtaagt ttttaagacc acaactgaaa attatgaact ctaagattca gcacttgccc
    32701 tctaattcgt tcgctatggc actggctagt gaaaccagca cgctagatgg gtttgcacca
    32761 acaaccgcaa ttcttgacga gtggcacgaa gcaaaaactc gtaaaacgta caacgtcatt
    32821 aagtcaggaa tgacccaaca aaagaacggc ttattgtgtg ttattagtac cgctgggctt
    32881 gatttaaacg ttcctatgta cgaggaatac ttattgttag atcgtgtgct aaaaggcgaa
    32941 gaacaagccg acaggtactt tatagcgata tgggaattgg acgatcccga agaaattcac
    33001 gatcaagaga aatggatcaa agccaatccg atttttgaaa gtgaagaaat caaaaaagta
    33061 atgattccaa ccattcaaga tgatgtgaac cttgctttga aacaaaataa ccttaattct
    33121 gtattggtga aaaacttcaa tttatggaga caagcgagtg aggacagcta tatgattgct
    33181 gaagactggc aggcaaccga agtagaacca caagatatta caggcaagcc cgtttatatc
    33241 ggagtggatt tatctaaaac agatgattta actagcgttt catggatcgt accgctagat
    33301 aacggcgaac tttattgtga ttcacatagc tttgtagcca ccaaatatgg gcttcaagac
    33361 aaagaaaagc gcgacggttt gccttatcga gaactagaaa aagctggtga gtgttccatt
    33421 actcaattag aaagtggaat cgtggactat gaccaagtat ttcagtttat tcaagatttg
    33481 attcaagaaa atgatttgga atgtatgggg atttgttatg acccgtataa cgctaattcg
    33541 cttatcagta aagctgaaaa agccaactac ccaatgttag aagtaagaca aggaacgatt
    33601 actctaaacg ttccgacccg aacttttaga gaacaagttt atgaaggcaa cgttattcac
    33661 aataaaaata cgattctcac ccatgcagtg aacaacgcta ttttaaaaac ggataacaac
    33721 ggcattcaga ttaataaatc aaagaacagt aacaaaattg atccaatagc tgcattaatc
    33781 aatgcctatg tgtttgcaat ggattacttc accacaacgg aaggagcgaa agcagacaat
    33841 gaattttata caagtgaaga attttctttc taattacatt cataccgttc ttttacttct
    33901 tggattggtg tgtgtgttgg ttgctatcac cttactaaca aatgtctact atggcttgtt
    33961 agcgctgggc atagtgctta ttggggtagc ggtcatgcta aatacagaac agaagggagg
    34021 ttaaaagatg gcatttttta aagcgagaca aaatacaacg ggagatcctt tcctacaaca
    34081 tgtggtatca atccaatcgg atgattacac caccagcttt acaagcgttc gtgcattaag
    34141 aaatagtgat gtgtttgcag ccgttcgaat tattgctagt gatattgctt caagtccgat
    34201 tcaattggtc aaaaacaata tgccacaagc tgataatgaa ctggtgaagt tactaaacga
    34261 gaaacctaat tcagaaatgg atggttggca tttaaagttt gctttggcgg tcaatatgtt
    34321 gctaaacggt aatagctttg cagagattaa acgcaacggt gaaaaggtag aagaaattca
    34381 cttattacct aactcaagtg taacggttac tcaattagat aatggtacgt tgtcttatca
    34441 gattggtgat aaaaaaagac gtgtgaagtc tagcgatatt ttgcacttca aatatttcac
    34501 ccaagatggt ttaacaggat taccaccact ttatgcgtta cgtgatgaac tgaaaattca
    34561 acaagctggc aaccgcacat tgcacaattt ctttactcgt ggtgtcagtg ggtcaggtat
    34621 tttgaaggtt cataagtcag atttagacgg atcagcaaag aacgcaattc gtgaaaagtt
    34681 tgaagaagcc aacggttcaa gtagtggaga taatgctctt agaacgatca ttcttgatga
    34741 aacaatggac tacaaaacat tagaaataaa caccgatgtt ttgaagctta tcaattccaa
    34801 tgattggaac acaaaacaaa ttgccaaggc gtttggtgta ccgattgagc gtttaggcgt
    34861 tgaaaatgaa cattctagca ccgttcaaag taatctccag tatatccaaa gtacgctgat
    34921 tcattacttt aatgtgtttg tgagtgaatt agatacgaaa cttgaaacca atatccgctt
    34981 taattccgat cagttactag agactgatcc tgaaacaaaa gtaaaaaatg tattggatca
    35041 ggtcaaaggg tcacttctca cgattaatga ggggcggtcg aaaatggggc taccccccat
    35101 ggatggtggc gatcgtttac tagcaagttt gaactttacg tatttagata cgttggagaa
    35161 atatcaatta aaagaacagg aaggagttac accagttgaa taatgaagaa gaaaaggaaa
    35221 aacggctgac agaagaagct gagctaacag ccgattctcc caaagtagag aaagaaaatg
    35281 aaaaacaacc aacagacggc aaaactattt caggctatgc gttgaaattc gggcaaccgt
    35341 caaaagattt aggcggcttt gtagaagtga ttacacccga agcattaaaa gaggtggatt
    35401 tatcaaatgt gttcttatta tatggacacg attattcaaa gccactagct agtgtcaaag
    35461 caggtacgtt gaaattgaat gtcgatgata caggattaca ttttgaagca gagctaaccg
    35521 acacgaccta ttcaaatgat gtgtatgaga atatctcaaa aggggttgtt gattctatgt
    35581 cctttgggtt cgtgcttgga ttagattcat tcgacaaaaa agaagatggc acaattgaac
    35641 gatcaataga taaaatcaaa gcacttaatg aaattagtgt cgtgaccgtt cccgcttatg
    35701 attcatcaaa tgtccaagta aataagcgtt cttacgaatc gtttatgagt aacaaccaag
    35761 caaaacaaac aaacaatagc ttagaatcca cttctaaagc acaaaaggag agtaataaca
    35821 tggaaaaaac tttaatcgat aacgaaaaaa cagaattgcg tgggtatgaa gaatatatcc
    35881 gttcacaagg cgaagtgcgt gatggagtca ctactgtaaa tgcagcggca gttgttcccg
    35941 aagaagtaat cggtgaagtc tttgatttga aacgttcaaa ttataactta gctcaatatg
    36001 caacagtaaa aacagtatca aatggacaag gtaaatatcc agtagcaact aaccaacaag
    36061 cagtgttagc aacaaaagct gaacttgctg aaattggtga tattgacgct gaaatgttta
    36121 cttcagttga ttataaagta gaaactcgtg ctggtaagat tgccttatca aatgaggttg
    36181 tggaagattc agcagtgaat attgtacaag aggtcaaaga tcagttagcg aaattggtag
    36241 aaaacactga caataagcat atcatggatt tattaaaaac attcactaag aaaacggctg
    36301 ctacgttgga cgatttgaaa caactataca atgtggcatt agacccagca ttaaataaaa
    36361 tggtaattct aaaccaaagc ggatattacc acctagatac attgaaagat tcagatggac
    36421 gttacatttt acaacccgat gtgacagcac ctagtggtaa atcattattc ggtatgccag
    36481 tagtattgat tgcagataca ttgtttgcca atcctaaagc tggaacattc cctatgatta
    36541 tgggggatat tgcacaatct atctttgttg ctcgtagaaa tcaagtaacg actcaatggg
    36601 aaaaattcga ttactactca caaggacttg cagtgatcgt tcgcaacgat tataagaaaa
    36661 ttgatcaaaa tgcttcagtg tatattgagt ttacgccagt tgtaacacca aaagtataga
    36721 aaaatattgg gcggcggttt atcccactgc ctttttttca ttaggagaga taaaatggta
    36781 attttggata gcataaaaaa aagtatgcgg atcgatcaca ctattgatga tgactttatt
    36841 caacaattga ttgatacagc aggcgaatat ataaaaagtg ctattgatag tagcgcaacg
    36901 gataaagata tggataatta tcagcaattt gatttggcgg tgtcattact tactcaacat
    36961 tggtatttga accgtcaaga agccagcagc gaacggatac cagtaacggt acaagcatta
    37021 gtacaacaaa tgagaggtgc ttattatgcc aatcattaag aatgtaaatg aattgactga
    37081 gagagtcaag tttaaaaaga caaaacgggt aaaagatgaa gatgggcaga tggtggatag
    37141 tgaagaaact gtatttgaat gttgggctaa tgtgcgttca caaatgctaa aagacgtgct
    37201 tgctagtgta ggtaccattc ttgaaggaac gttgacgttt attattcgat acgatcaaga
    37261 ttatgaacta acaaacgata tgaaagtagc ttggaaaaac aagagttata aaattatttc
    37321 aatcaatgaa ggaacggcgt ttaaagatta tacaacgatc atagctaaac agatttctta
    37381 gaatgattac acttgtaaac gttgtgggta tttagtataa ttaaggtagt aaatgaaggg
    37441 ttagctgcct gaattttgca agacttagct agtcgaaatc tattgttgga ctgaaaattg
    37501 taggtgtggt tgcaaacatg ctggactaag aaagatgata gatgatgaac gttcaatttt
    37561 aatacaggca tgctaggact gattggatgg ttttggcaag ctgattgtgt agaaatcaaa
    37621 gaacacgtct gttgtggacg tgtttttttt gttataattc aaaagaggtg atttaatgga
    37681 caaagcagag tttacaaatt tttattggaa gtattatcta catttagaaa atgagtttat
    37741 taataccaca gattttgtga tgctcgatga gaataatttc aaaacattct ctattgaata
    37801 tcaaaaacta ctactagcga ttggttcgga gtgtgagatt attttcaaag aactttgcgg
    37861 atttgatagc agtagcaata aaagcataac tgattttaaa gctgttatta aatctagcga
    37921 attaatgtgt ttggataatg gtgttagggt tatgaattct ttaacattga cttcactaaa
    37981 accttttgga gatgggtggc ctgaagatac accagattgg tggaaaatat ataacagagt
    38041 aaaacatggt cgttcttcaa attataagga agcaaatttg gaaaatgtgt tgtatgcttt
    38101 agcaagtcta tatttattag aggaatattt gcataagaaa gtaatactag aaggtgaagt
    38161 agactttata agtccagagt caaatctatt tacgttatct tgggaaagaa aacattcgtc
    38221 gatgcaaaaa gtgacgtttg aaaaagtgga ttcaaattat gtagctccac tcattgattt
    38281 taaagaacaa gaagaaattt aaaaaccccc acggcttatt gaagtttttg tatgccatat
    38341 tgtatgccat ttggtttaaa tcgcttgaaa aatagtgata gataactcta attcatttag
    38401 tcataaacgc tgttttgata acctttatag ttctttgata tgggtttctc attcatggcg
    38461 gaagaagaag aatagaacaa aagaatgaat taataagata taaaaaaagg gattgtgaca
    38521 aacgtcttgt cacaatccct ttttccaaat aaacgatgtt caatcagctg cccctcggca
    38581 ttcgctcgaa aaacggcgaa atatgaagaa ctattttgcc atttgtttct ctaataatca
    38641 ggtcaaaacg ttgacttcac agtctcttcc ttaaacggtg ttctcctgcc aactcctcgg
    38701 tcacaagtca caatattcaa caaacatgag aagctgtttt ttgaaattgt tccttgtgac
    38761 tcggagctga acggcaggct cacgacctct ttcttaaacg gtgttcaaaa gcttgcatct
    38821 gcggtaataa gttcaaccaa acgaaaatta tgaggagcta tttttgtttg gctgttctta
    38881 ttacttgatg caggacagct ttttcacaac ctcttttcgt ttagcactaa atttccttaa
    38941 aaagtagaaa agctttcgaa gcctcgtttg tttcttttac tgtataataa aagaaaagag
    39001 taacaatcgc taaaagatat aaacaagaga aaggaaatac aagatgattg gtctgattta
    39061 ttttgtggtg atcgttctgg cgaacacagt tggcgctatt tccgggatgg gtggaggcgt
    39121 gttgatcaaa ccgattcttg atcttatcgg cgcccattct gttgcaggga tttcttttta
    39181 ctcaacagtt gcggtattca cgatgtccat tgtttcgact gtgcgacaag tatcaagcgg
    39241 gaaatcactg aattggcaga ttgtcggttg ggtatctagt ggagctgttg ttggaggagt
    39301 agtcggcaac attgtattcg aagttttttt acagttattt gaaaacgaga agcatgtgca
    39361 gctgatccaa atttttttga cggtattgac cttggttttt gcgttcttct acaccaagca
    39421 tcatcagcca aaatttcatt tgacgtcatg gacttggtac cttatatgtg ggggggttct
    39481 gggcttttta gctagttttt taggtattgg tggtggacca gtcaatgttt ctttgttgat
    39541 gctgatgttt gcattgccaa taaaagaagc aacactatat tctctatcta cgattttctt
    39601 ttctcaactg gcaaaattgg taacgattgc tttaacaagt agctttatgc gctttgattt
    39661 atctatgttg ttttatgtta tccccgctgc tgttattgga ggtttgtggg gagcaagatt
    39721 tagcagggtt ttgtctccaa aaaaagtgac ctttattttt caagtaattg tcctcgtggt
    39781 tcttttggtc aattgttaca atgcctttgt catcttacaa acattaggag aatctagact
    39841 aacgcaagtc aaaatcactg aaacatattg ttctaaatga aaaaaggagt atactgtgat
    39901 aaaaaaattc atttaaaaaa ataaaaattg gctggtgatt tggatgttgc gggaaatgcg
    39961 tttaggagat gcagaagcac tacgagaaat caatgcggaa caattaggat atgatgtacc
    40021 attaaccgtt acggtgagac aaatgaagaa actgttgaag gagccagaaa aaaatttttt
    40081 cttggtctat gaagatccta cttctaaaaa agcagctggc tatgtacaag cggagtccta
    40141 tgaatcgatt ttcagcgatc cgatgttcaa tattatggca cttgctgtgt ctaaacatgc
    40201 tgaaaaaaga ggaatcggaa aggccttgat gactggcgta gaagaagcga aaagacgagg
    40261 aatatcagca ataagactta attctgcaga atacagagta gaagcacacc gattttatga
    40321 acgcatcggt tatcattccg ataaaatgca aaaaagattt ttgaaaatcc tgtaaatttt
    40381 tatcaaaaaa tacctggtca tcaagccgat acttgatgat caggtatttt ttttgactaa
    40441 gaaagtaatt gcatcaagaa acctgagatg atcaaaacga tggcaccacc aagccgattg
    40501 cccatttgag caaaagcaat aagttccatc cgattagctg cagataagac agctacattt
    40561 cctgtaccac ccatcgagtt gttgcataag ccagcagtaa tagttgattc gattggatat
    40621 aaaccaaaca aacgaccgac aaatcctgaa actactgaaa tcgcgataac acttgtcaaa
    40681 cataagacaa caaattgcca tgtcaaagca gaagccaata catttagatt caataacgca
    40741 ataccgatac cggcaagaac agctgctgtc aagtttttga caatcaagtt gttgaacatg
    40801 atagctgcat cttcgtaata ttctggtaat aggtttgcga ttttacagat aacaacgata
    40861 atgatcatga atgcgtaagc atggacttta ggaacaaaat agttacagat ttgtcctaag
    40921 atgaagaaag tcaatgatac catcaaaccg acacctaatt gtggaatgga aggttttaca
    40981 tttctaggtt ttccatcgcc aaggtcgcct ttttccatta atttaccatt accgttgaat
    41041 tttggcattg attgtcccgc acgagcaact aacgctgcac caatgatagc taggacattt
    41101 gtcattgctg tcgcaggaat caggcgggaa atgatagaag aagcgtccgt acctaaaaca
    41161 tttgcataaa tcgttgataa aggtacagct ccggctccaa caccaccagc cattgcgggc
    41221 aatgagatat ataaaacgga atttgcaaaa ccatttccga taagcatacc tacgagtcct
    41281 acggcaaaaa aggagacgac cattgaaata agtgcaacgg gaataaaacg aacagaagct
    41341 ttcatcaata gattacggtt cataccaagg atgctaccag taatcaaggc agcaatataa
    41401 aagtctaaaa agcccatatt gctgacaaag ttttctgtgg attttactac atactcaggt
    41461 aagatcccaa atgtagcaat cgcggcagag gcaaagatcg caaaaacgga gccaccacct
    41521 aaataacttt tgacgatagg gatttttgtt ccgataaaat gaaataaatt accgaaaatg
    41581 accaaaacag cgattgggcc aatcatattc gtcggtaatt ttcctaaagc cattgcaatg
    41641 atcaggacaa ggaccatgat caaataaagg ggcaaactta cgccggtaat ttttgttgac
    41701 caaaaccctt cttttttctt ttcctcaact gcagttgcgg ttgttgtttt ttgtgccatt
    41761 tttacagatc ctttcttatt ctgtatcgta tgaaaaaagc caaagagaag cggcaaaaga
    41821 gcagtagttg gctggctgct gttttgccgc agtcgctttt ttctttttag acgtcataca
    41881 aagtttctgt atgttctttt actataacaa tcttaatctt ctaaagattt atattcagga
    41941 acccatttag cagattcaac agcttctttg atatccgtga tttcttcacg attcaatttt
    42001 tgtgcaacaa ctgattttgc gacagtttca gcaatcgttt gagagaattc agtgattttt
    42061 gctactggag gcaagatagc tgctcctggt tttgttacat caacgattcc gcctaatgct
    42121 cgactagctt gagaaatgat ttcagcattt actcgtgtag ctgttgaagc aatcaaacca
    42181 agccctaaac ctgggtacat caacgcatta tttgcttgac cgatttggta agttacaccg
    42241 ttatattcca catcagcagc agggatacct gttccaacta aagcttttcc gtccgtccat
    42301 tcaatcaaat cttttgcttt tgcttctgcc aattttgttg gattagacaa aggcatgatg
    42361 attggacgtg gggtatgagc cgccatttct ttcacgattt cttcagtgaa tgctccaggt
    42421 tgggtagaag taccgatcat gatcgttgga tggattgctt ttacaactgc ttctaagttt
    42481 gtcaattcat cagcattagt gaattctgag cgtttacgag cgaatgggat ttgaccagga
    42541 gtcaatcctt ttgtatcttc aaacaataaa ccctgtttat ctacttgata gaaatgttgg
    42601 cgtgcttctt cttcaggtac accttgacgg atcatttcat ctaaaaggat gtttgcgata
    42661 cctacaccag cagtaccagc accaaatgtc aagatcgttt gatctttcaa ttgctcacct
    42721 gatatattca atccacctaa tacaccagct agtacaacga ttcctgtgcc ttggatatca
    42781 tcattgaaag tagtgatttt atcttcgtat ttttctaaga tcgttgcagc atttcctcgt
    42841 ccaaaatctt cccaatgtaa taacaattct gggaataatt cagtagctga ttgaacgaat
    42901 tgatcaatga attcgtagta agtttcgcct tctacacgag catgacgatt ccctaagtat
    42961 aatggattat tcaataattc ttcgttatta gtaccagcgt cgattgatac aggcaagact
    43021 tgtgcaggat tgataccagc cgcagcagtg tagaccatca atttaccgat agcgatgtca
    43081 acaccgttca caccccagtc acccatacct aagattcctt ctgcatctgt cacaacgatc
    43141 aaacgaatgt cgcgtccatc tgctgcgttt ttcaaacttg ctttgatatt ttctggttcg
    43201 tcgattgaaa gaaatgcagc atcttgtggt ttcaagaaaa tttcgttgta ttgttcgatt
    43261 gaatccgcaa cgacaggatc ataaacgaca ggcatgaatt caactaaatg ttcgcccatc
    43321 aatttataaa acaatgtccg gttcgtattg aatagattca ttaagaagat acgtttttcc
    43381 aaatcggtct gtttgcttaa gtattgaccg taagcttgga cagattgttg ttccaatgtt
    43441 tggacagtac ttggaagcat accagtgatt ccgtattttg cccgttcttc ttttgtaaaa
    43501 gctgttcctt tatttagaaa aggattattt aataagttta gccctgtaag catgaatgat
    43561 tcctcctaag ttttaataca aacgaagtat aggagtcaga tgaggatata gtcaaaaaga
    43621 gcaggtataa taaattttat ttatatgagt aatagagtca aaagaaatca aaatagcggt
    43681 atttgttctt tttatatcaa caatccttgc ttgattacta tgcgtatctc ttatatgcta
    43741 aagaaagaaa agtagaagaa taaaggatat gttagataga taaatagaat ctctgaagaa
    43801 taaatcacgt gatcgtgacg ataaaataca cttacgtcag gtgataaaaa atacataagt
    43861 agaaaactaa gaggaggaac agaaaatgaa agaagttcaa ttgatcagaa aaagcgaact
    43921 atcagaaggt ggttgcaatg catgcggcgt agtagaagca acaagctata cattaaagct
    43981 tggtgccaac aaagcgataa tctctgagtt gacagtaggc ggtcttgtgg acagtctggc
    44041 gcttgctgaa ggttttattg gagaagatat ttatgagatg ttttcagaaa tccgtcagtt
    44101 aaaaaaaggg gaaaactgca tagaggttca tcatgagagc ccgaatgtga gattcaaacg
    44161 tggtgataat gagatgatct tcaataatca tgtgtccgat cacaccgagc tatatggaat
    44221 cgtgaatcaa atactaactg agctttttgg attgggacct tatgcgttca aggaagaaaa
    44281 cggtaatcca aaattaaacg aagaatggca agaaacgatt gaaatacaaa gaaacaaccc
    44341 gcacttattt caataggcat ccacagtatt tcgtaaaagg gactttgaca cgacttttgt
    44401 caaagtccca tcgtttttta tctatttgtg ttctaaacat ttctttcaga gtagtaacaa
    44461 ctggaatgac tgaaatgtaa acagattatt tgcctgtatc aatacggaag agtaatataa
    44521 agtgtgtaaa cgctatcata ttattcattc aattttttat agagggaagg cattgaaatg
    44581 gaaaaaacgt atcaagcagg tacaaatgaa ggaatagtgg attttatcaa tatggaagat
    44641 ttagaaatag ccgcttcaca agtgattcca gctggtggtt atggttacat cagcagtggt
    44701 gctggcgact tatttactta tcaagaaaat gaacgggcat tcaatcatca gctgattatt
    44761 cctcatgtat taaaagatgt agaattaccc gatacaacta cacattttga caaagaaacg
    44821 ctgactgcac caatcatcat ggcaccagtt gctgctcatg gcttagctca tgtgaaggcg
    44881 gagaaagctt ctgcaaaagg tgtagcagat tttgggacga tctatacagc aagttcttac
    44941 gcttcttgta cattagaaga gataagagaa gcaggcgggg agaaagcacc gcaatggttt
    45001 caattttata tgagcaaaga tgatgggatc aatttggata ttcttgaagt ggccaagcgt
    45061 aatggagcaa aagcaatcgt attgacagcg gatgcaacag ttggcggaaa ccgtgaaaca
    45121 gaccgcagaa atgggtttac cttcccactg ccaatgccga tcgttcaggc ttatcaatca
    45181 ggagtaggcc aaacgatgga tgctgtgtac aaatcttcca aacagaagct tagtccaaaa
    45241 gatgtagaat ttattgctgc tcattctgat ttgccagtct atgtgaaagg tgtccagtca
    45301 gaagaagatg tctatcgttc attagaatct ggtgctggcg gaatctgggt atctaatcat
    45361 ggtggccgtc aactagatgg tggtccagca gcgtttgatt cgttgcaata tgtggcagaa
    45421 gcagtagata aacgtgtacc aatcgtgttt gacagcggtg tacgacgcgg acagcatgtt
    45481 ttcaaagcaa tcgcatcagg tgcagatctt gttgctattg gcagacccgt tatttatgga
    45541 ttgtctttag gaggaagtac aggagtccat caagtgtttg atttctttaa aacagaattg
    45601 gaaatggtca tgcaattagc tggaacacaa acagtagaag atatcaaaaa aataaaattg
    45661 cgtgagaatc gttttattta agaaacaaat gacgaaaaaa ataggagtgc ggcagatgat
    45721 gccgtactcc tatttttata gttcaaggat gtcactaata gaataatttg aaacgaaaaa
    45781 ataaaattga aatatttttt catacttaat aaaaaaggaa gaatattcat gtaaacgatt
    45841 ttattgtttt tttctctttt atacaaaaag ggtcataatt tcaagtaagc ggatgaattc
    45901 atgaggattt tttgcatact gtctctacta tacttaggtc actaagaaaa aggagtgatt
    45961 tattatgaaa aagaacatga ttgggacatt attactttca acacttcttc taggcggctt
    46021 ggcaacacca gcttttgctg agggtcaagc gacttcaaaa ggagatatta cctttactga
    46081 accaacaaat accgtggagc ctcttaaccc tactgatcct tcaaaaccag tagagccagc
    46141 agatccggaa aatccagcaa ctggccagac aggtccttta acactggatg tagttcccga
    46201 attgccattt ggtacacacg agattgaaag cggaacaaaa acgtatcaag tagacgcttc
    46261 aaaaaacgat acaccttatc tccaagtatc agatcgtcga ggtgtaggtg cagatggcca
    46321 agcacaaggg tggaacgtga cagtttcggt ttcagatttt gtaaacggtt cacaagtttt
    46381 gcaaggcgct gaattagatt ttggaacatc cactgttaaa agtacgtcag ataacgaatc
    46441 cactggacca actagtcaaa ctgtaactgg gttgagtaaa gcaagtgcag cgacaccaat
    46501 atttacagca gcaaaagatc aaggtctggg aacatggctt tctgtttatg atccagcaaa
    46561 tatcacactg aaagtgccga aagcagcagc tggaacattc acggctgatt tgacttggaa
    46621 cctcgtggct ggcccagtag catagagtat gaaataaatt caacaaactg cggtgaaaat
    46681 actataggtg aaggattttt taccgcagtt tttgttgaaa ggatgtggtg gacaatgaat
    46741 caaagtaaac gactgtttgt ttcgtttttt tctattttaa gtctattttt catttttccg
    46801 tcaatcagcc aagcaaagga ttcagcagga gactttggaa tcaaaccggt atttccagag
    46861 aaccaaatag ataaagcaat cggttatttt gatttattag tggcaccgga acaaaatcag
    46921 acactagaag taattatcag caattcttca gatgaagaac gaacatttga ggtctctgtc
    46981 aatccggcgg taacgagtga tggtggaacg atcgattata gtcaaaaaaa cccaacgtta
    47041 gatgagacat tgccgtttga tgtccgtgac gttttgctca ttgcgaaaaa ggaaatcaat
    47101 gtatcagcac atgcagaaac aactgtacct atagaagtga aaatcccagc aaaaagcttt
    47161 aagggacgtg tattagcggg tattcatgtt tcacctaaag aagaagctga aacagaaaat
    47221 gctacagaag gagcacaaat caaaaatcgt attgcttata atctcgcagt cgttttacaa
    47281 gaaagtcaag agacgataga accggatctg aaacttttat caggagattt ggacgaggtc
    47341 aacgcaaagc caactgttca gcttcgtttc caaaatcctc agcctaggat tatcagcaat
    47401 ttgatattta cgagcaagat cttttatgaa aatcagcttt atattgaaaa tacgtctaat
    47461 gcatttttag ttgcaccaaa ttcgaatttt cacttgaatc ttgatttagc tggtgataaa
    47521 gcaaaagccg gcgattaccg cgcagaaatc atagcaaaat caggcgacag taatgaatgg
    47581 cgatttacac aaaactttac gatcaaaaaa gaaaaagcac aaaaagtaaa tgaaaattcc
    47641 gtttttgcag tacaagaaca atctttccca tggctttatg caggattggt tgctgcagtt
    47701 ctagtgttat ggttgatttt gctgtttttg tgggtccaca agaaaaagaa aaaaggagaa
    47761 acaacatgat gaggtgattt cgttgaaaac atcgatctta ttgggaggga ttattgcaag
    47821 tttgctgttc ttcagctggc aagagccagt ccaagcagat accaaaagtt caggtacgat
    47881 tacattttat gatctaagtc caattccgca tccaagtggt tcagtcaatg gcgcatcaaa
    47941 acagcagaca cagctaccga tttataaaga atctaatcaa catggcgtat tcccggagac
    48001 gaatgaacaa aagatccgtt ttctttattt gatcattggt atagaattat ggcttcttgc
    48061 gtggttgttg ttatggagaa gaaaggaaaa ggaggatgaa catgttgcta caaaataaat
    48121 tttcattttt tcgctccttc ttttttactt cgctttttgt tttaagtata tttatctttt
    48181 caccttcggc agaagctgtt ggagcaacgc ctcctgccat ttcttatgat ccatacacgt
    48241 atgaaaatat cgtacctcca aatggtggac gtagtgcagt caatggcggg aagcttgtcc
    48301 aactaactgg ggctaaccaa ttgcctaaat tgactgctac ttatttgaac gatggttcaa
    48361 atgatccttg gaaaggtggc acggtccgtt ttcattggga aagccatgtg aaactaacaa
    48421 atgtacttga tttggtgaat atcactgcac aaggatttgc atttgtggcg atcatcaatt
    48481 tgccggaaca tgtatcaagc agtgatgtat taaaagcaat tgactggaac aacgcctact
    48541 tgtatattgc cggtgccccc atcaaggtta ctagcggaag tttattatca gcaggaagcc
    48601 ataccttgcg ttttgggatg gggtcgtggg atacaaatac tctattgaca gatattattg
    48661 ctattattac gcgaggcgaa ttcaacgtgg acgatatccc gcttcaattt gatgttacag
    48721 ctaatgtcgc gaagatgaca gaaaacggag ataaatatga tacgagtcca aacaaaattt
    48781 tgaccaaggg taaattacaa ccttctatgt ctaaaaaggc cgttttttct gttgattttt
    48841 atgattcgaa taatattatc caagatcgta tgttcaattc gattttagct ccagctgcag
    48901 gtagatttta tcctaaatta actggcggaa acttgaatcc aggagcatat gcattttctg
    48961 caagtgcaga gataaatacg tggaatagtt acatctcacc aagtgattca acaggaaaat
    49021 ataatacatt tgctgatacc acagaatacg tggatggaaa taaccagaac cttccaggct
    49081 ctaccaatag tcggacattg acgatggggc tgactgaagg acgttttgat cagttgccat
    49141 ttagtcgctt tgatcgcgta gtcaactatt ttacaggaaa aaacgttaca caaggagcaa
    49201 tactgactca tactccagca agcacaagtg gattgaatca gacagccaat atcgtgtaca
    49261 gtgggaaaga tgcgcaaggc ggattgcttt ctcctgttgc tttaaaggta ttggagcagt
    49321 acaagctaga cggaacggtt ttaccaacaa acttaacagc cgatagtcag tggggaaagc
    49381 tcctttcttc tgcatcgtac caagtcacgg ccaattggtc agcaactgaa ctaaaaaagg
    49441 gttcgatcca ttacaggctt tattcgaaag gaacccaaaa attagcgaca ggatggacag
    49501 atcaactttt ccaaacgatc caatcaaata acgggggtgt aaatacagct acttctacac
    49561 tacctgcatt ggcttcaggg caatattatt ttgattatcg cttggtggac gatgtactta
    49621 ctaacatgta tccgtctttt gcgtacaaat ggcagtctga acaagctgga atcaccactc
    49681 ttcctcaaat aacagtggct aattttccat ctgtgagtgc agatagtcag ctaaaaaacc
    49741 ttagcagaca acctgagaca ggagatcccc tgtctgctct atcaggagat acgattcaag
    49801 aaaatgtgac attcacgtta acaaaatctg gggatgcgat aaccgacaaa aaaatcacga
    49861 tctcacttcc tgaaaatact acttatatca atggttcctt aaaattaaat ggtacaacta
    49921 tcgcagatac cggcattcaa caaggagttt ctgtcccagc agatctattg agcaaaatag
    49981 gagataccat tcatcttact tacaactatc aattaaatac tgtagatact tctttacaat
    50041 ccgtcagcat actgacaaag gcagctgtac tttccagcaa tattacatta gcagatggtg
    50101 ctaagcttcc taacccagtt gtccaaacat ctgctaaaac aattcttgtc cccaaacaag
    50161 aattaacatt agttaatgta ccagatgatt ttacatttgg taacgatctc cccaaaccgt
    50221 tgaagacaag ttattatgaa tcaaaaggcg atttttcttt tgatgtgcgg gatactcggc
    50281 ttccaagcac gtctccttgg caactgacag gtacattgac ttctttattt aagaatgatc
    50341 aaggtcaaga attaagcgga acaaaattat acttcaatca ttctggatca aagcaattga
    50401 ttcagcaagg tcaaaacacg ttgatttatg agagtgatgg aacagctaaa ggagaggttc
    50461 tcgttgactt tcccgatacc gatggtttac tcttagaggt aaatagcagt acgaatgctc
    50521 aacctggcgc aacgtatcaa ggcatggtca catggaaact gacagctggg ccaaccagct
    50581 aagtgattag aatttgtatg gatctgtgat aactgtcaca gatcctcttt ttcaaggatg
    50641 agaaggaaac ttctgctgtt aaaatcagaa atgcttgaag gagtggactt ggaacttttc
    50701 agtttgcttg aaaaaaatga acaacggcaa atcaaacttt tccaactttt attagaggaa
    50761 aaaggagagg tttccgttaa taacgtactt acccgcttat cagttgatcg ggctaccttg
    50821 aaagaagatc tgttttattt acaagctaac ttggaaaata tcaaacaatt ggaaattgtt
    50881 atccaagaag ggaatatttt attaatcaga catggaaata tagcagcagt cgatgtttat
    50941 tatcattgtt acttgcgcta ttctacaaaa tatcagatac ttctttatct gttggaaaat
    51001 ggctcatttg atcggcagaa acttgtcatg gaacttaata tcagttcggc tactttgtct
    51061 cgcagagtga aggaattaaa tgattcttta aatgagtttc atctgaaaat aaaaagcggg
    51121 cggctgaccg gtccagaaag tcaaattcgt tatttttatt tccaattatt ttggtttgga
    51181 cgtccctatc ttgaaaacaa aaaagaatac agtgatttat caggaaacac ttttttagat
    51241 ctgctgcaaa aagagtttag ttttgctatt acagaagaag gacgattgaa atttgaaata
    51301 tggctttcca ttatgaagaa gcgaatgcgc tgtacgaaaa aatccaaacc agattatagc
    51361 aatcttcctg ttggattgtt tcaaacgaca caatttttat tggacctcca tacatttttg
    51421 acccgttact tctttcaata tgcctttcct tggaatcaaa atgaaacgtt ggttttttat
    51481 cttttcatga tcagtaactt tacattagat acacataact cgcatgtcca ggagtttttg
    51541 ataagcgaaa aatacaaaga cgacgtagta gctcaattga atcgaacgtt taaacaatcg
    51601 atagaagaat atttctcttt ttatgttttt ccagaagaga tttcgcaaaa gattgcgttg
    51661 acagtgatgc aaaatcacgc tcattttgcc tattttagag gatggatgaa tatttttggc
    51721 caagaaggat taaaacagcg gttaactgaa gtagaagata aacaattcct ggttttatgt
    51781 gaaagattgg tcagacaaac atttgctatt gttgatttta ctgaagtaga cgaggaaaat
    51841 gcccgctttg aattatttgc tcgctatgca tctattttac ggacgctgat caagcagtta
    51901 gaattacgtc tgcaaattgc ttatgatctt ccttatgaaa ggctaatggc ggatatcgtg
    51961 aaagaaatca tccaggaaca attgctgaat acgatcaaat atgatttagt cgaatacgag
    52021 aaagaaaagc agtatgatat cattttgact agccaattga aagagtaccc gtcacagaag
    52081 tccgctaaag tttttgtatt cactagcaac gaatataatt atgatttccc ctatttgaac
    52141 caatttttaa aagaatgtta tttagaaaaa ttgaatttaa ggatgaataa aacatgaaaa
    52201 tcgtgatcat tggtgcttcc catgcaggca tcacagctgc cctaaatcta agaaaacttc
    52261 aaccgaaagc agaagtttta ctgatcgatg aagatcataa agatggacta ggctatgttt
    52321 caaatggaat caacctttat ttaaaaggaa agatacgtag tttagctgaa gttgcccata
    52381 acatgcggac tcttcaagaa agtggggcaa aactgatcac cgaatggaga gtaactgaac
    52441 ttgatccaga caaacatcag ctcatcctcg catccaaaga aggaaaaaac gagaccataa
    52501 cctatgataa attaatcgta gcgacaggtt cctctcctgt caccttgtat aaacaaattg
    52561 aagctgaaaa tgtctacacc tataaaaatc tagtgcaatc taagcaagta cttgccgctt
    52621 taaaagaagc aaaagaagta gtgatcttcg gtgctggtta cattggattg gaattagcag
    52681 atgctttgag aaataaagga tacattattc atctagttga ttatatgccg aatgttttat
    52741 caagatattt cgataaggat atgatcaaca gttttcaaaa tcagctgcaa actaagcaaa
    52801 taaattttta tccaaatgaa ttcttgatcg attggaaaaa atcagaagag aaagtagtat
    52861 ccgtacaact tctgtctcaa acaataaagg cagatatggt cattttttct gcccaaactc
    52921 gtcctaatac gacattgtta aaagaaaaag tggctttgta tgaggatgag actgtgatag
    52981 tcaatgaata tctgcagaca agtgatccgg acatctatgc gattggagat atcgtcccag
    53041 tcagttttga caaaaataaa cggcatctct ttttaccttt agttactcga gctgtacata
    53101 tggcaagagc agtagcgcta actttgagtg gtcagccaac cgcttacgac ctcagacaaa
    53161 agataacagc agcagtcatt atagactact ttttaggaac tgtagggctg acagaagatg
    53221 aagcgccatt cttggaacaa aataccggtt cgtgttcagg agaatttgat ctatttccac
    53281 aatacgacga agaaaacaaa acagtaaatg caaagctgat ctaccatccg gatacattag
    53341 aaataattgg cggacagctg ataagccaag aattcttatt atcagatttg aacctgcttg
    53401 cggatatcgt gaaacacaaa actacgattc cacagctagc agttgaggat tttggatttc
    53461 tgtctgaata cacctctcgt tttcactacc tcaatgagtt agcttttaaa gtactagcta
    53521 agagagcaaa tagcaataga gtagataaaa gactgtgaga aatatcacgg tcttttattg
    53581 tgtggggata taataaatat taatcaatcg agaataaaaa attcatataa tgaaatagcg
    53641 gaagaatttt ttgagcataa tattcgccaa aaatttatca agtgataaaa ttgttgtata
    53701 aaatgattat ttcaggagga ggagttaaat gtttttagca ttaaatgaaa ttatgcattc
    53761 aaagttacgt tatgcgttag ttgcaggggt gatgtttttg atcgcctacc tggtattttt
    53821 tttgactggg ttagcttatg gcttagctca agataatcga acagcagtcg acaagtggga
    53881 ggcagattcg attgtgcttt cgaaagatgc aaattcaaat ctagggatgt ccatgattac
    53941 taagaagata gcagaagaag tcgaaggtgg gaaagtggcg tatcttgccc aaacacctgg
    54001 agtcgtgact agtaaagaca gtacagaaga aggaaaaatc aatgttagct tcttcggtat
    54061 cgataaaaat caattcatca tgcccaatct tgttgaagga aaagcttttg ataacgatga
    54121 tgaggcagta ggcgatatta gtttgaaaga agaatatggt ctagccatag gagatacagt
    54181 taagttatct ggtagtgaca agacgtttaa actaactggc tttacggatc atgccaaatt
    54241 caatgtctca ccagttctct atacaaccat caatgcttac caagaaatcc gcttcgaaaa
    54301 agaagataca agtgaaaatg cacggattaa cgcaatagtt gtcagaggta aaatcagtaa
    54361 tttacctgaa gatttagaac agatcaaaat ttctaaattc atcaatgaat tacctggata
    54421 taatgcgcaa gtattgactt ttggatttat gatcggattt ttgatcgtta ttgcggctat
    54481 tgtgatcggg attttcattt atgtactgac gatgcaaaag attaatatct ttggtgtaat
    54541 gaaagcacaa gggatcacag gaggatttat tgcgcgttct gtagtggcac aaacattcat
    54601 tttatcattt gttggtattc ttcttggtct attaggaaca gtgggaacat cccttgttct
    54661 acctgatgcg gttccattcc aaagcaattg gctgtttttt ggcgtcatta gcttgttgat
    54721 gttagtagta gctgtgttag gcgcactatt ttctgttcgg acaatcgtaa aaatcgatcc
    54781 gttgaaggca attggataag aaggaggaag aacatgaaag caatagaatt taaagaagta
    54841 gaaaaaagtt tccaagatgg cgaccaagta gttaaagcat tgaaagaaac aaccatgagt
    54901 atcgataaag gggaatttgt tgcaatcatc ggtccttctg gttcaggtaa aagtactttt
    54961 ttgactttgg caggcggatt gcagacgcct agcagtggct ctgtatttat caatgatcaa
    55021 gaattcagta atcaaaaaga aagcgaacgc gttaaactac gttttaaaga aattggcttt
    55081 attttgcaag cttccaatct ggttcctttt ctgacagtaa aaaagcagtt attattagta
    55141 gataagatta aacatgaaca tcgtcaaaaa gaagcaaacg aattatttga gcagcttggc
    55201 gtggataagt tgatcaacaa gtatccagaa gaactatctg gtggagaacg gcaaagggtc
    55261 gcaatcgctc gtgcattgta caatgatccg tccattattc tagcagatga accaactgct
    55321 agtttggatt cagaaaaggc acgagaagta gtcgatatct tggcaaaaga atcaaaagac
    55381 aaaaataaag caacgatcat ggttactcac gatacacggc tgattgacaa atgcgataga
    55441 atatttatga tggaagatgg tgtattgaaa gaaaaagaat aaccaaaaag caggtggaaa
    55501 aatggtccat cgatacaaca aagatacaca gcaaaaaatt ttgaaagaag cgactgactt
    55561 gtttatgtcc aagggatatc tcggcacttc aacaagagaa atcgcacaaa aagttgggat
    55621 cacccagccc aatctctatc attatttcgg tgataaagaa aaactatata cggcagtttt
    55681 agaaaaccac ttaaaagatg ttggaaaagc tttgagagaa atcgttcaaa caagcgaaac
    55741 gggatttcaa gtaaccttga caaaaatggc gcagtttttg attgagacac atctggtcga
    55801 tttgtttctg atgcttcacg atcttgaaag caatctttca aaggaaacaa gagatcatct
    55861 tttctttcta tggaagaaaa attatcgtga accttttgaa gaaatctttt cagcaaacca
    55921 atctgtgcta agaaatggga tttcaaaaga aatcgcagca aggcattttt tcttagtgtt
    55981 agcaccttac atcactcggt cgaaaagacc tgtggaagaa ccgctaaatg tggcgcaatt
    56041 gatcgattta tatttgaatg gtgtattagg agaagcgtaa agctgttata tagggagaaa
    56101 atagttaggt gaagaagcaa gatatgacga agatcgttat atcttgcttc tttatatagg
    56161 tagtttttca taaagacaaa tttgttattc tctcatgatt atcagggtat atttttattt
    56221 attatgtcgg tgttccagga agtgttttaa tttaataacg aagaaattaa ttgtttgtag
    56281 aatgaaggaa actatttatt gggtagatga atcaccacga atagtcaaaa ggagatttca
    56341 ggatatgcca aaaatgaaaa aaatcatttt agcagtaatg ttattttcta cggttatatc
    56401 ttttacagcc ccttttttgc ttacttaagc tgattttaag ttttggccct tagtctggat
    56461 ctacgaggtg agagtcaaga atgaaaaaaa taattggagc ttttgtattt gcaatcatta
    56521 tcattattat ctgttttcaa atagatgttt ttggtcaaaa aaagatagtt ggacaaacgg
    56581 tcagcagtac gaacagtacg gttacaaaga caaaggaatc atttgatgat acagaacaag
    56641 agacattaat caaaatcgga aaaaatgacc gtacactata tacagatgac tcgctaacta
    56701 ccccacttgc aactataaac ggcggagagc tggcggagtt tctttctgaa acaaaaaatg
    56761 cttatcagat caagacaaat gatggctata ctggatattt agccctcgaa gatggaacca
    56821 aagtcacaaa gaatatacaa acaaaaccgg aagagctatc tgatgcagtg attgtattag
    56881 atcctgggca tggcggaaat gatactgggg cattaagcaa tgatgaacaa acagaagaaa
    56941 aagatataac attaagtaca gccataaaag taaaaaaggc gctagaggat gctggagcaa
    57001 cggtttattt gacccatact acagatgaat tagtacagct tggagatata tgcgactaca
    57061 gtgaagaaaa aaaggcagat gtctttatca gtttacacgc agactctacg gaatatgcga
    57121 atgaagcaac tggaatcacg acatattatt actatggaca agaggaaaca ttagcacaga
    57181 caattgctga ctccttcact gatctgcctc tggattcaag aggaatctcc actgggaact
    57241 atcaagttct tcgagaaaat cttcaacctt ctattttaat cgagatgggt tatatgaata
    57301 atgatagtga tttaaaggaa ttagtaacag acagttatca gcagcagatt gctgcaagtt
    57361 tgacacaagc attgaccact tattttcagt aataaataag cccagccaaa caaaaatagc
    57421 tcctcatatt tttcgtttgg ccgggcttat tatcgcagat gcaagctttt gaacaccgtt
    57481 tattttttta gtagcttcaa agctttttct gtatttgcaa agtgaagttt ggcatatttt
    57541 tcaagcatag gcatgccgcc tttctccaat agttttgccg ctacttggtc agatttcgtt
    57601 ccagctcctg atggaagggt gattccagct tcagctgatg ctttgtgtaa ctcttccaaa
    57661 aagctggcac gactgatgat agaagcagca gcaacagcta aatgatattg ttctccttta
    57721 gtaacgaagt acagtttttc ttgtaattga tttttttcta aacgcgcata ttttttaaaa
    57781 tttgcttccg gcgtaaactg atcgatcaaa atcgcttctg gtttttctgg ctcgattttt
    57841 tttagcagca aatggatcgc ttgattgtgc aaagcgactt tcatccgaac ggcattgtat
    57901 tttggttgga tctcattgta tttttctgga gataagacaa gcagtttata ggggatggtt
    57961 ttttttaaga tgtcagcaag ctggatgatt tggctatctt ttaactcttt tgaatctcta
    58021 acaccaagtt tacgtaattc tgcaagctga tcacgtttca cataagcagc acatactgtt
    58081 agcggaccga aatagctgcc atttccgacc tcatcactac ctaaaacgga taattgactg
    58141 atattttttg gcaaagaaga ggctgttttt gctggcttgg cttgtttatc ctgtgcctcc
    58201 ccccatttat cagcttctat tgctgcattc gtaccttgaa acatcacttt tccggatgta
    58261 taagcggtaa tggtcgtccc gtcttttttt gcagcaaagc tagtataagg aatctgttta
    58321 tttaacaaat aagagcgata gtatgctttc atttgactaa gttggtcgtt tgttgctttg
    58381 ataatgacgt tgctcataaa attctcctcg tttttataca taaaactata ccgcaactca
    58441 cgacttttcg ttttctaaga gattgcgaga catagcattt ttttaaagtt tatcatataa
    58501 tagttaagta tgtgaaaaat atttgtggag aacggtgaaa gaaccaactt catggtacac
    58561 taaataaaac tttcatcaaa taggaggaaa tgattcgtat ggcgcacgaa aaaacacgct
    58621 acaaagcggt gattgccaac caaacatata ctattatcgg acgggaaacc aagcatcata
    58681 tggatatcgt aacgaagctg atcaatgaac agttagcaga attgaaacaa ttatcaccac
    58741 aaatggataa tgaacaagca gcaatcttga tggctgtcaa tgcgctttcg gatcaattga
    58801 agaaacaaga aagaatcttg gagctggaag aagaaacagc agaattaaag aaaaaaatga
    58861 tcaaatttac agagcttgaa aatcgtgtga aacgcattga agcaatcgag aacgaagctc
    58921 gggaagtatt gaaagaaaat ggtcaagcag atcataccat taaaaatcat gtggaagcac
    58981 aacagatttt aaacgagaaa cgaaaaggac aaattaaaca aaaatcttct aattaagatc
    59041 cttttatcaa aataagaaaa atttaaaaaa agttagaaga gaaaggaacg tagcatgctg
    59101 agtttgctga ttttattttt attgctaatt gcgttttttt ctggagcacg tcgcgggttt
    59161 gctttgcaaa tcatattcgc gattggatat gtattgtcat ttattgctgc ccagcatttt
    59221 tacaaaccat tagcaagtca tttggaatta tacattccat acccagctgt cacgccaaca
    59281 tcaaagttag cattttttga tcaggtattt gcctttcacc tagatgaagc tttttatgca
    59341 ggaactgctt ttctgattat tttgctaatt ggctggctgc ttacccgatt tgtgggggtt
    59401 tttgtccatg gattgacgta tgtgccgatc ttgagacagg tagactggat tgcaggaggc
    59461 atcctgtcac taatcatggc ttacgttact atatttttga ttttgcagtt acttgccttt
    59521 gttccattag atgtggtcca aaatcaattc ggcgagcata gtttcgctcg ctttatcgtt
    59581 gagagaacgc catttcttac caacaagatg tatgagcttt gggtaacgaa tattttgaat
    59641 taaggaaaat agtgctggaa aatatttcgt tttttgtaca gagtagatta tttaagaagg
    59701 ctgcgtagcg tatgtccggc acagctcttt tttcatagtg aaagataagg tgataaaatg
    59761 aataaccgaa tccttgaaac attggaattt gaaaaagtca aacagatggt cagacaattt
    59821 gtagtgactg cacaaggaaa agaagaactg gcagaattgg taccagtgag cgaggaacaa
    59881 acgatcacaa actggcttca agaaactgag gatggattga aagtgcaacg tctgcgaggc
    59941 gggatcccta tacctaaact tgaaaatatc cgtccccata tgaaacggat tgagatcgga
    60001 gcagacttga atggagtgga gcttgcacaa gtttccagag tattgtctac gacaagcgaa
    60061 ttgaatcgtt tcattgatga tctttatgac agtgaaatcg aatttgcacg tttgtatatg
    60121 tgggcagatc agttagtcac gatccctgtt ttgagccgcc gtttaaagga agcaatcgat
    60181 gaagacggac gcgtgactga tgacgcttct cctgagttaa agagcataag acagaacatt
    60241 cggcgaagtg aacaagctgt tcgtgaacag ttagatggga tcgtccgtgg gaaaaatgca
    60301 aagtatttaa gtgatgcgat catcaccatg cgaaatgacc gctacgttat cccagtcaaa
    60361 caagaatacc gcggtgtatt tggcggtgta gtccacgatc aaagtgcttc aggatagact
    60421 ttatttattg aaccaaaaca agtggtggat ttgaataatc gtttgcgtca ataccaaatc
    60481 gctgaacgaa atgagattca acgtatttta agtgaacttt ctgctgaact tgttccccat
    60541 cgtcaagaaa tcatccacaa tgcttatgtg attggtaaaa tggatctgat gaatgcaaaa
    60601 gcacgatttg gtaaagaagt aaaagctatc gtgccgggaa tcagtgaaga caatcatgtc
    60661 gtcttgaaac aagcaagaca tccactgatc gatcaggaaa aagtagtttc taatgacatc
    60721 acaatcggaa aagactatca agccatcgtc attacaggac ctaacacagg tgggaaaacg
    60781 atcacgttga agactttagg tctgttacaa ctgatggggc aagcaggatt accgattcct
    60841 gcaggtgaag aaagtcaaat cggtattttt gaggaagtat ttgcggatat aggagacgaa
    60901 cagtcgattg agcaaagtct atcgaccttt tcttctcata tgacgaacac tgtagatatt
    60961 ttatcaaaag tcaatgaaaa aagtctggta ttatttgacg agctcggtgc aggaacagat
    61021 ccgcaagaag gtgctgctct agcaatcgca atcttagatg atcttggtaa aaagtctgct
    61081 tatgtgatgg caacaacgca ttatcctgaa ttgaaagttt atggatataa tcgggcaaat
    61141 acgattaatg ccagcatgga gtttgatgtg gatacattaa gtccaacgta tcgtttgctg
    61201 attggcgttc ctggacgaag caatgcgttt gaaatctcta gccgattagg tcttgataca
    61261 gaagttattg atgaagcgaa gcagttgatg aatgatgaga gccaagattt aaacgaaatg
    61321 atcacagatt tagagaatcg ccggaaaatg gcagagaccg aatatctgga aatgcgtcat
    61381 tttgtttctg aggcacaaga acttcacgat gatttgaaag aagcttacag ctatttcttt
    61441 gaagaacgtg aaaaagaaat ggaaaaagca aagaaaaaag caaatgaagt cgtgtcagag
    61501 gcggaagaaa aagcagaaaa aatcattgct gatattcgta aaatgcaaca gcagattggg
    61561 caaggaaatg tgaaagagca tcagttgatc gatgcaaaga cccaattagc aaatctacat
    61621 caagaagaaa ctttgaagaa aaataaagta ttgaagaagg cgaaagaaca aaaaacgttg
    61681 aaaccgggag acgaagtgtt ggttacgact tacggccaaa gagggacgct tttacgtaaa
    61741 aacgggaatc agtggcaagt agaaatcggt atattaaaaa tgaatgtgtc cgaagacgag
    61801 ctgacgcctg ttgctcctca aaaagagccg acacaacgag ttatccatgc tgtacgatct
    61861 gaatctagta gtcacgtgcc gaatcaattg gaccttcgag gaaaacgata cgaagaagcg
    61921 ctaagtgagg tagatcaata tttggattct gccattctag ctggttatcc tcaagtgact
    61981 attgtccacg gaaaaggaac aggcgcactt cgcaagggaa ttactgatta tcttaaaaac
    62041 catcggagcg tcaaaagctt tgagtttgca ccggcaaacc aaggcggaaa tggtgcgaca
    62101 attgttaaat ttaagtaaag cttactaaag gtaagcagat ggttcgctat ccaagtatag
    62161 aaatgctata ctagtcatag attttaaaaa tggaggtctt tgatatgtca caagtaatta
    62221 cagataagac atttaatgaa gaaacagata aaggacttgt attgattgat ttttgggcaa
    62281 cttggtgtgg tccatgtcgt atgcaagcac cgattttgga tcagttggaa caagaatatg
    62341 atgaagaaga attcagaatt gctaaaatgg atgtggatga aaatccagaa actcctcaac
    62401 aattcggtat catgagcatt ccaacattaa tgttgaaaaa agatggtcaa gtagtagaaa
    62461 aagctgttgg tgttcattca aaagaacaac tacgtcaaat gatcgatcaa tatttataaa
    62521 aacttacagc aaaaataagc tgagggtggg actgaatcca gttccgtcct cggttttttt
    62581 gcggttgagt taaggttatt caaattaata ttttttgagt ataattacgt tgtcaggctg
    62641 gattgttttt ttgacagaca tgctataata actttaattg aatatgaagg ggagtaccag
    62701 atgaacgaac gaatcaaaaa caaattagct ttacttcctg atcagcccgg ctgttacttg
    62761 atgaaagata aaaatggaac gatcatttat gtcggcaaag ccaaaatatt aaaaaatcgt
    62821 gtccgctcat attttactgg tagccataat acgaaaacgg aacggcttgt tagtgaaatc
    62881 gaagactttg aatacatcgt tacagaatcg aatatcgaag cattgctctt agagatcaat
    62941 ctgataaaga aaaatgatcc taaatacaac attatgttaa aggatgataa aacctatcct
    63001 ttccttaaga taacgaatga aaaatatccc cgtttggtga ttactcgtaa ggtactaaaa
    63061 gacaaagcac tgtattttgg accatatccc gatgtcggtg cggcgaatga gacaaagaag
    63121 atcctcgatc gattatttcc tctgagaaaa tgcaaaccta gtcagacgaa ggagccttgt
    63181 ctttactatc atttgggaca atgtctgtgt ccttattatt tcgacgtaga tccgaaagtc
    63241 tatacgaaaa tcgttgatga agtgaaaaac tttttaaacg gaggacacga aaaaatcgag
    63301 tcagagatcc atcagaaaat ggaaaaagct gctgaaaaca tggagtttga aaaagctgca
    63361 gaataccgag accagatccg tgccattgag acaatcatga ctcgccaaaa aatgacaaat
    63421 actgatttac tggatcgaga tgtatttggt tatgcgattg ataaaggatg gatgtgtgtc
    63481 caagtgtttt tcgtaagaca aggaaagcta attgaacgag atgtttcaat gtttcctttc
    63541 tataacgaag cagaagaaga tttcttgact tacctcggtc agttttatca ggaaaatgag
    63601 catttcattc ctaaagaagt cttgattcct gatacgatcg acaagcccag tgtagaagct
    63661 ttgttagcta cgaaagtgct gcaaccaaaa cgaggagaaa agaaaaaatt agttgaattg
    63721 gcgagtaaga atgcctcagt tgctttgaat gaacggtttg atctgattgc cagaaaacag
    63781 gaacggacga tcggagcagt tgaacgttta ggaaacgcga tgaatatccc gaccccaata
    63841 cgtatcgagt cttttgataa ctctaatatc atggggacga atcctgtggc tgcgatggtc
    63901 gtattcattg atggaaaacc ggcaagaaaa gaatatcgga aatataaaat aaaaacagtc
    63961 aacggaccgg atgattatgc atcaatgaga gaagtcatct atcgcagata ttcgcgagtg
    64021 attcgcgaag ggttgccttt acctgatttg atcttgatcg atggaggaaa aggacaagta
    64081 gatgtggcaa aagatgtctt agaaaatcaa ttaggaatcg atattcctat tgctggcatg
    64141 gcaaaaaacg ataaacataa aacaaatgag ttgctattcg gtacagattt ggctgtagta
    64201 ccgcttgagc gaaattcacc agagtttttc ttactccagc gaatccaaga tgaagtccat
    64261 cgattcgcaa tcactttcca tcggcagcta cgcagtaaaa acagttttgc ttcccgatta
    64321 gatgaaattg aagggttagg accaaaacga aaaaaaatgc tgcttaaaga gttcaaatcg
    64381 ttgaaaaata tcacagcagc cacgacagaa gaattacaag aaatcggact gccgaaaaat
    64441 gtcgcacaaa acgtatttga taaattacat caggaatgag gaaagggcac tttacaaaga
    64501 aagtaaagtg tcctatcatt ttatgtacaa caaaaagagc gtttacgttt tgttggtaaa
    64561 taataaatcg cttacgtctg gtgtctaagg atatatgtga tttcttgaag aaggagtgaa
    64621 gaaatgttag aagtcaagga tcttgttaaa acttttggga actacacagc tgtcgatcat
    64681 gtctctttcc aaatccccga tggaaaaatc atggggctaa ttggccaaaa cggggctggg
    64741 aagacaacga cttttcgttt gatcttggat tttttgacac aagaccaagg agaagtgtta
    64801 tggaatggcc atcatcttgg ggagaaagat tatgatgtca tcggttatct tccggaggaa
    64861 cggggacttt atccgaaagt aacgattcaa gaccaactgc tttattttgc agaacttaga
    64921 gggaaatcaa gaaaagagat tgaaccaaaa atcgactttt ggatggaaaa atttcaggta
    64981 aaagggaaaa agacggataa agtaaaatct ttgtctaaag gaaatcagca aaaagtccag
    65041 ctgatcgcca cgttaatcca tgaacctaaa ttgatcattt tggatgagcc attcagcggg
    65101 ttagatccgg taaatgctga attgctaaaa gatggaatat tggaattgaa aaaacatggt
    65161 tcatgtgtca ttttttctag ccacaatatg gataatgtag aaaaaatctg cgatcatttg
    65221 atcatgttgc gaaacggaaa aatggttttg aatggaaaag tacatgagat tcgtgaatca
    65281 tttggccgta cgaagttatt cttggaatct ggtttaagcc aacaggaagt agaagaaatc
    65341 gaaggcgtga aaaaagtgat ccttcatgaa gacaatacgt tagagattac cttagaagat
    65401 cctgaagctg ggaaagaaat ctttactcgt gcgactcagt tcggctacat tcctatgttt
    65461 aaccagcaac cgccaacttt ggaagagatt ttcaaattga aagcaggtga aatcgatgcg
    65521 taagttttgg attattacca aagatgtcta tttaaaaaat gttaagtcga tttctttctt
    65581 gatcatgata ttagtccctt ttatcatgct gggtatcatt tatgtagcag gaaactttgc
    65641 tcaacaaaat agtgatgtca ataaaatcgg cgtattggct gataatgagc aaatcagtca
    65701 gcaaatgagc caagtcaaaa cagatgattt tgagttcaaa gcagttgatt ctgaagaaaa
    65761 agcacaaaaa gagctttcgg aagaaaaaat cgatgcgtat ttagtagtct caactgagaa
    65821 tgataagata aatgggatgc tttatagcga aaattcatta ggacaaagta cacaactact
    65881 gatacaacaa caactgactg gcttgcaatc gatgcttcga gcgagtcaat taggcatttc
    65941 accagaagaa gtagctagct tgagccaaca agcaagtttg actcgacaaa aagtcaattt
    66001 tgattcaaaa ggaaaaatga cagtcggaga agataactcg acagtccaat acgtcgtaag
    66061 ttatgtagca acgattgtct tgttcattat tattttgacg tatgcgcaga tcattgcaca
    66121 agagatcgct tctgaaaaag gcacgcggat catggaagtg atcctgtcca gtacgactgc
    66181 acaaaagcat ttttacggaa aattaacagg tgttttactt gttgcattaa cgcaaatggc
    66241 attatacggt attatttttg gtataggata cagtcaattc aaagatatgg aaatggtcaa
    66301 aaatatatta gacggtatct cattggataa cttgattgga ccattcttgt ggtattctct
    66361 tctattcatg atctttggca ttttgatttt ttctgtttta gcagctttat gtggctcttt
    66421 ggtcaacaaa gcagaagata cagcaaaagc aattttgcca gtgacttatc tatctctagg
    66481 cggatacatg cttggattga tactaggagc ttcagatcca aacaatatcg ttattcggat
    66541 cacttcgtat attccattct tatcttcata tattatgccg gttcgcttag caaatgagac
    66601 agtcggtatg ggtggagcat tgatttcctt gttggtactt gtagccgtaa cattcttatt
    66661 gatgatcttg tctgcaaaca tgtacaaatc gaatgtactc gtttatagcg aaggcggatt
    66721 atggagttca ttgaaacaat cgatttcaat tatgaggaat gaacgaaaaa aagcataaaa
    66781 caatcctaaa atacagaagg aagctggaca tctattgttc ccagcttctt tttgtataga
    66841 cctattttat ttattttact atattggata tatattcatt gaaaatagtg tataacaact
    66901 ttataatatt gagtatacca atttttggag gcgttttaat ggaccgttat ttagatttac
    66961 tttcagaaaa attcccctca acggaggatg tcatcacgga aatcatcaat ctcgaagcaa
    67021 ttttgcagct tccaaaagga acagagttat ttttgagtga tatacatggc gaatttcctg
    67081 cttttgatca tattctgcgt atcggttcag gaaatcttaa agaaaagatc aaagaccttt
    67141 tttctgaaca aatgacggaa acggatatca gccaattcac tatttttacg gcttatccag
    67201 aatatgcatt aacgactgat tggtacaaag aacaagataa atcgcagctg atccatcatt
    67261 tgatcgatct tttacggttt acgacagtca aatatacccg gtcaaaagtt cgaaaaggat
    67321 tgccgaaaga atatagctat atcattgagg aactcttgta tatcgatgac cgtatcaatg
    67381 gaaaaaaaga ctatgtaaaa aaaatcattg aacaacttgt tttgatgaag gaagaagaaa
    67441 aatttttaac gaaacttgca cagacgatcc aaaaatctgt catcgatcat ttgcatatcg
    67501 ttggagatat ttttgaccga ggaactcaag cagccaaagt gatggatcga atcatggatt
    67561 tttcttctgt agatatccaa tggggaaatc atgatatttt gtggattggt gcgtattgcg
    67621 gctctgaggc atgtttactg acacttttac ggattgcagc acgctataat tatttatttg
    67681 aattagagaa agaatatggg ttgaatttac gtccattgtt ttcttttgct catcaaactt
    67741 atcagaagaa tccagtattt gcgcctaaaa acagtaaaaa tctatccgaa agagagcaag
    67801 aagaattaga aaaaatccat caggcacttt ctatccttca attcaaatca gaacatcagt
    67861 tattggatcg tcgacctgaa tttaaaatgg acgatcgtaa attgctggaa aaaatcgact
    67921 atgaagcatc aacgattgat ttagaaggtc agctctatga gttgaaagga acttgttttc
    67981 aaacgatcca gccagatgat ccaaaaaaat tcttggaaga ggaacaaaaa gtgattgata
    68041 gtttgatgta ttcattccag cactctttga gaatgcaaaa acatatgacg tttttgatcg
    68101 aaaaaggggg aatgtatctc acgaacaatc agcatgtgct gtttcatggc tgtatacctg
    68161 tagacgagaa gggacagctc ttagcatttg aattagacca atcttatcgc ggaaaagaac
    68221 tgctgggctt ttttgaaaaa cagataactg aaagcgcaaa agatctgact gcaaaagaag
    68281 atttagcaac cgatttgatt tggtatgcgt ggagtgggcc attttcgcct ttattcggca
    68341 agagtaaaat ggcgactttt gaacgttatt ttctcacaga gcctcatacg cacgtcgaga
    68401 aaagcaatcc ttattatcac ttgcgagatg aagagtggtt cagtgaaaaa attttagcag
    68461 aattcgacac aaaagaagaa gggtcagcaa tcattaatgg gcacacgcca gtaaaagtaa
    68521 aaaaagggga gtcaccgatc aaagcaaatg gaaaagtatt tgtcattgac ggaggtttat
    68581 ccaaagctta tcaaaaaacg acaggaattg ccggttattc actattatgc aattcttatg
    68641 gtttccaaat cgtgacacat tatccgtttt tgcctattga acaacaattt gcaaaaaaat
    68701 ccgaccaaac aaatgtgaaa aaagtaatcg aacagcaact accacgcaaa ctcaatcgtg
    68761 atacaacaaa aggtatggaa ctgcagcagc agattaccca gctcaaaagg ctgttggact
    68821 atcgaaagga cgattgagaa gaattccagt gaacattgtt ccatagactg gagactgaga
    68881 caaaagtcgt gtcgcagtct ctttttccgg ataaacggtg ttcttctgcc aactcctcgg
    68941 tcacaagtca cactattcaa caaacatgaa aagctgtttt ttgaaattgc tccttgtgac
    69001 tcagagttga acggcaggct cacgacctct tggtataaac ggtgttcaaa agccagtttc
    69061 tcggtattaa gccaaattta tgcaaaaatg tgaaaagcca ttttcacaaa atttttctta
    69121 atactcgaaa ctaaacagct ttttcacaac cccctcagaa agtctattaa aattcattca
    69181 caaagaaatc gaataagcgc tgttcagatg gatgtacacg gtgggtaagt tccggatgcc
    69241 attgaacacc gaggatttta tgcatatcat ctttgctttg aaccgcttca atgagtccat
    69301 cgttagaaaa agcgatggct tttaataaag gtgaaagatc tttgactgcc tgatgatggt
    69361 aagaattcac aaaatatgga tcggggagaa ggttgcttaa caaactgtct gaaacaatct
    69421 tgacttcgtg agtcgtaaat tgcggggcag tgggctgttg ttcatgtttt actgaccact
    69481 ttggatataa tgaaagatct tgataaagtg taccttccaa aacgacattc aatagttgga
    69541 gtccccggca gactgcaaaa attggttttc tttgtttcaa tgcttccaag atcagtgcct
    69601 gttcaaattg gtctcgttga atatttgttt ccgttagctt tggatgagga tcttccatgt
    69661 aaagttgtgg actgacatct tgaccacctg caagaataag tttgtcgatt tgtccaatca
    69721 gttgaggagc tgaatctgga gacatgactg gcagaataag aggcaatcct tgagcatcta
    69781 aaactgcatc cacgaatcct tgcggtgtat agctcacttg atttccttgg aaagtatctg
    69841 ttgctcgaat cagttgattt ccggcaatgc cgatgattgg tttcatttgt attcccccta
    69901 aagtagactt attgtaacaa ggatttaaaa aaaattaaac tatgtaagac ttgcccctat
    69961 acttatctgt tcttgctgtg ttactatctg taaagagaaa tttcgtgtga aattcatgac
    70021 gatagttgaa aatattgctt aatttgttat aataaaaagt aagcagaaat aaaaaggttg
    70081 ggcgtaagct tcaaggatct agttcttcaa ggggtgagaa ggacatttta ttgaaggggc
    70141 ctgcctatac taagttatct ttagaggtac atactttcaa tgaaaaaaga aagcatgtac
    70201 ctctttttta aatcgaaagg aagtgaagca agtgttagaa gctttggaac aaatccgaaa
    70261 agcagaagaa gaaaatgaaa agcgtgctca aacactgcgg cagcagctga agatctatgc
    70321 aacagaaaaa gagcaggaat tggaaacgat ccaaacaaac tatcgacaac aactaaaaca
    70381 gttggtggaa gaaaaagaac aatttgaaat acaagaatta gaaaaagaaa aaatgaaatt
    70441 gaaagcagaa gcagacaagg tgcaagcaac tttgaaagat caatatcaaa agcatcagag
    70501 tcaagcgatc ggtgcgatca ttgaaagggt gaaagaaact tatggccgtc actaagatgg
    70561 aaaaagtgac cctcatttca gataaaagaa atcaggagag gattttacaa gcagtacaag
    70621 gaatccaaaa cgttgaaatc cgggatctgt atcaaaatag aacaaacaac cagtgggtgg
    70681 agaagtattt tccagatacc acgattattg ataaagaagc aaaattaagc gctttaggta
    70741 atcggttgaa agacatccaa gaagctatcc aattcataca acaccacggc gatagccgtc
    70801 aaaagaaact ccatttgaaa cgtcaagaac tttccttaca agatttggaa gccaattatt
    70861 ccgaagaaaa tttcataaat aaattgaaag aagtccttga tttaaaagaa aagtgggaac
    70921 aactaactga agaacgtgat cgtttagaag aagaggaaga atggcttctt cattggcaac
    70981 agctggatat tgctccaagt atgtatgcaa gtaagacgac catttttgag atggggactg
    71041 tgagtgcagc aaattttgaa agtttcaagg aagaactgag taagcttgat gacgtttata
    71101 tggaagaaat agattatacg ccaaaacaag tttatctttc gtatgttgct ttaaaaaaat
    71161 cagttgctgt tatagaagaa attgctggga aatacgggtt caataaagaa acgtatcctt
    71221 atgaacaaaa tcctaaagaa aaactgcaag agaccaagca gcaattatcc attgttcacg
    71281 agcagcaaaa gaagataacg acagcgttag gtcagtgcag tggctatatc caagaatttg
    71341 aatgggtaga agaagtcaca cttgccgttg cagaacgaga aaaaataaaa gaacggttta
    71401 tccatgcgac ttatctgatc gttttgcaag gttgggtaga tgcagaagaa aaacagaatt
    71461 tgctgcatgt gttaaacgaa accgtatcag aagaagatat atacgtcagt ttcgaaacac
    71521 caaactcaga agagattcag caggaagtcc ctactaaatt gaaaaaccat ccgcttgtcg
    71581 aaccttttga attgctgact gaaatgtaca gtctgccaaa atatgaagaa gtagatccaa
    71641 caccttggat gacaccattt tatcttgtct tcttcgggat gatggtcgca gatgttggtt
    71701 atggtttgct gatgctcatt gggacaatac tagctcaaaa actacttgtt ctaccacgcg
    71761 ggatgaaacg tttcgtaaaa ttctttgaga ttctctcgat accatcgatc atctggggat
    71821 tgatctacag ttcatttttc ggacagtcat taccaaaaga actgtttggc atccgcttgc
    71881 ctttcccaat cctatctacg acggatgacg tcaatacgat tttgatttta tccgtgattt
    71941 tcggtctgat acagattttg gttggattat ttgtggcagc aaaggaaaat atcaggagaa
    72001 aagattactt gagtgctgtc agtgatggat ttgcctggca agggatccta attgggatcg
    72061 ttattgcgtt ggttggtgcc atgttgataa aaaatacagc atttgtttac cttggcgctg
    72121 ggctatcgat cattgctgcc ttatgtatct tgatcgttcc gattatccaa acgccgtcta
    72181 aagtcaaagg tgctgccaaa ggtgcgtata atctttacgg actgaccggc tatatcggtg
    72241 atttagtcag ttatacacgt ttgatggcat tgggtatttc aggcggaagt attggagcgg
    72301 cattcaatat gctagttgct ttcatgccgc cagctgctcg attcagtgta gggatccttt
    72361 tgatcatcgc tttacacgca ctgaatatgt ttttgacact gctaagtgcc tatgtccatg
    72421 gcgcacgatt gcagtatgtc gaattttttg ggaagtttta tacaggaggc ggacgtgcct
    72481 ttgatccgct gaaaacggcg gaaaaatacg tcaacatcaa tcacaagaaa aaaaacaata
    72541 aataattgga ggatttttat ataatgatgg attacttaat tagtcaaaat ggtggaatgg
    72601 tatttgcggt attagcgatg gcaacagcga cgattttttc agggatcggt tcagctaaag
    72661 gtgttggaat gacaggtgag gcagcagcag cattgacaac aagtcaaccc gaaaaattcg
    72721 ggcaggctct gattctgcaa ttgcttccag gtacgcaagg tttgtatgga ttcgttattg
    72781 cctttttgat ttttatcaac ttaggaaatg acatgtcagt tgtacaagga ctgaactttc
    72841 taggtgcttc tctgccgatt gcttttacag gcttgttttc aggtattgcc caaggaaaag
    72901 tcgcagcggc aggtattcaa attttagcga aaaaacctga acatgctaca aaaggaatca
    72961 tttttgctgc gatggttgaa acatacgcga ttttaggttt cgttatttcc ttcctattag
    73021 tgttgaatgc ctaagcataa aggaggaaaa gcagatgaac gccattgaaa aaatcatctc
    73081 tcagatgaac gaagcagcag agcaggaaag agcggcgtta gaacaagaag agcgaatgaa
    73141 gatcgatcaa aactttgaac aaaaacgtac gcaagttgaa acagaacatc aaaaacaaaa
    73201 agaaaaacaa atcgaattac tcgaaaaaaa ataccgtcag ctaaggaatc gccagcaagt
    73261 agaagtacga caagaaaatt tgaatgcgaa gcaggaattt ttaagacgat tgtttgcaga
    73321 tgcggtaact gaaatggaaa attgggatga atctgaacaa atccagttta tcaaaaatgc
    73381 attgtattca ttacctttga caggaaaagt agcattcatt gctggagaaa aatcagcagc
    73441 ctatctttct cagacgttgt tggatgaatg gaacaatgaa cttcccttta tgatggtttt
    73501 aagtgatgaa actgttgctg atcaagcggg ttttctgata aacgatcaag gagttcagta
    73561 taattttctt ttcagcagcc ttgtacaaga tatccaagga acgatgagtt ttgagattgc
    73621 caatcaatta ttcgaataag gagggatcag tgtatggaat accacgaact aaatcccttg
    73681 attcgcggaa gagagcttga acttttgtcc aatgagacat ttgaacggat gattcaaaca
    73741 aattctgtcg aagcacttgg tgaaatattg aaatccacga tttacagtcc atatatttat
    73801 gacggatatg aatatgactt cgaacagaat cttttaaagg agcagagccg tctatttcgc
    73861 tggttaaagg aatcagcacc ggagcctgaa atcgtttgga tctatacgat gcgttatact
    73921 ttccataatc tgaaggtttt gacaaaagct gagatgacaa atcaaaatct ggaccatttg
    73981 tatatcgacg atggatttta ttcattagaa accttgaagg atgccattca tacgcaagtt
    74041 tcaaatgaac ttcctgaaag cattatggac agtatacgag aagtacgtga ttattttgaa
    74101 gagtctacca ttcttcaggg aattgacgtg atttatgatc gacagttttt gacagagcag
    74161 cgacggcttg ccgataagct aggatatcaa gaattgctga cagaagtcat tgcttttatt
    74221 gacttgacca atatcacaac gatggctcga ggaatattgc agaaaagaac atatgggttc
    74281 atgacgacgg tactttccag ctcgggaagt atcgaaaaag aagtattttt gaactttgta
    74341 gataaagata tggaagatta cacgaatttt ctattagaga cagattatgc tgattttctg
    74401 cgccctgtca tccgtgaggg aaatattgat ctcgtaaagc ttgaacagtt gaaagatgat
    74461 tatctaagtt cattgtatca agaagcacaa acccaggctt tcggaccact gccactacta
    74521 gcctttttga acgcaaaaga ggtagaaagc aaaaaccttc gtttactggt tatcggcaaa
    74581 agaagccatt tcgaatcaga aacaatcaga aagcgggtga gacaagtcta tgacgcataa
    74641 gatcggtgta gttggcgaca aagattctgt tttgccattc aaattgtttg gctttgatgt
    74701 tcgttatggt acaaccaagc aaaccgttcg tcaggcaatt gaagaaatgg caaagaatga
    74761 gtatggcgtg atttatgtca cagagcaatg tgcagcattg agcccagaaa cgatcgaacg
    74821 ttacaaggaa caaatgatac ctgctatcgt attgattccc aatcatcaag gatcattagg
    74881 gatagggctg gaagaaattc aaaaaaacgt agaaaaagca gtaggtcaaa atatcttata
    74941 gtatgaaaag gagatagaaa ttttgcaaat tggaaaaatc ataaaagtct ccggacctct
    75001 tgtaatggct gagaacatgt ctgatgccag tatccaagac atgtgtctag tgggagatct
    75061 aggagttatc ggagaaatta tcgagatgcg tggcgatgtg gcgtctattc aagtatatga
    75121 agagacttct ggaattggtc caggcgaacc ggttcgctct actggtgaag ctttatctgt
    75181 tgaattagga ccagggatca tttcacaaat gtttgacgga atccaacggc cattagatac
    75241 ctttatggaa atcacacaaa gtaatttctt agggcgcgga gttcaattgc ccgcattgga
    75301 ccatgagaaa aaatggtggt tcgaaccaac agtagaagcc ggagaaacgg tgagtgctgg
    75361 agatgttatc gggatcgtag aagaaacaaa agttataaaa cataaaatca tggtgccaaa
    75421 tgggataaaa ggaacgatca aaacaatcga aaaaggttca ttcactattg atgaaacagt
    75481 atgtgtcatt gaaaccgaaa atggtgacaa aaatttgacg atgcttcaaa aatggccagt
    75541 aagacgtagt cggccaatca aagaaaaatt aaacccggat gcacccatga tcactggaca
    75601 gcgagtgatt gatacattct tcccagtgac aaaaggagga gcagcagctg tacctggtcc
    75661 ttttggtgca gggaaaacag tcgttcagca tcaaattgca aaatgggccg atgtggacat
    75721 ggttgtctat gtgggatgtg gcgagcgtgg aaatgagatg acggatgttt taaatgaatt
    75781 ccctgaattg attgacccta atacaggaga atcgttgatg gaacgtacgg tattgattgc
    75841 taatacatca aacatgccag tagcagctcg agaagcttct atctatacgg gaatcacaat
    75901 tgcggaatat ttccgtgaca tgggttatga cgttgctatc atggcagact ccacttcacg
    75961 atgggcagaa gcacttcgtg agatgagcgg acgtttggaa gaaatgcctg gtgatgaagg
    76021 ttatccagct tatcttggtt cacggcttgc ggaatactat gaacgatctg gaagagtcat
    76081 tgcattagga tcagaaggtc gcgaaggaag tataaccgca atcagtgctg tatccccgtc
    76141 tggaggggat atttcggaac cagtcacaca aaatacattg cgggtcgtaa aagtattctg
    76201 gggtcttgat tccagtttag cccaaaaaag acattttcct tcgatcgatt ggatacaaag
    76261 ctattctctt tattcaacag aagtagggaa gtatatggat catatccttc aagctgactg
    76321 ggcatccatg gtcaccgagg gcatgcgtat tttgcaggaa gaacagcagc tgaatgaaat
    76381 cgtgcgtttg gtagggattg attccctttc agataatgac cgtctgacat tagaagtggc
    76441 aaaatccatt cgtgaagatt atttgcagca aaatgctttt gatgatgtcg atacattcac
    76501 ttcaagagag aaacaattca aaatgttgaa gatgatcttg acctttggtg aagaaggacg
    76561 ccgtgcgttg tcgttaggtg cttatttaag tgagatcatg gacggtaccg tatcgattcg
    76621 tgaaaggatc ggacgaagca aatatatccc ggaaacagaa ttagaaaaac tagatcaaat
    76681 tattggtgaa atcaagcaaa cgatgcaaac gatcgtttca gaaggaggca tgagcaatga
    76741 ttaaagaata tcgtacgatc ggtgaagtcg tcggtccatt gatggcggtt gaaaaagttg
    76801 ctggtgtcaa atatgaagaa ttaatcgaag tccgtatgca aaatggcgag attcgtcgtg
    76861 gacaagtatt ggaagtccaa gaagataaag caatggtcca aatattcgaa ggaacaagtg
    76921 gtatcaattt acgtgactct tctgtacgat ttttaggcca tcctttagaa ctaggtgtat
    76981 cggaagacat gatcggtcga gtattcgatg gtttgggacg accgaaagat aacggaccag
    77041 agatcctgcc tgaaaagcat ttggatatta acggagaagt aatcaatcca gtagctcggg
    77101 attatccaga tgagtttatc caaacaggta tctctgcaat cgatcatttg aatacattag
    77161 ttcgtgggca aaaattacca gtattttctg gctctggtct tcctcataaa gaattagctg
    77221 ctcagatcgc gcgacaagca acggtactcg attcatcaga tgatttcgcc gtagtctttg
    77281 ctgctattgg aatcactttt gaagaagctg aatttttcat ggaagatttt cgtcaaacgg
    77341 gcgcaatcga ccgttctgtc atgtttatga atttagcaaa cgaccctgca atcgaacgta
    77401 tcgctactcc tcgtatggct ttgactgctg cagaatatct tgcttatgaa aagggaatgc
    77461 atgttttggt tatcatgaca gacatgacca actatgcaga ggcattgcga gagatttctg
    77521 cagcacggcg agaagttcca ggaagaagag gatatcctgg gtatctttac acgaacttag
    77581 ctactttatt cgaacgagca ggaagaatcc gcggactaaa aggatcggtt actcaaattc
    77641 cgattctaac aatgccagaa gacgataaaa ctcatccaat ccctgacttg actggttata
    77701 ttacagaagg acagatcatc ttgactagag agctttacaa gagtgggatt cagccaccaa
    77761 ttgatgtact cccgtctctt tcgcggttaa aagataaggg aactggaccc ggaaagacaa
    77821 gagaagacca tgcagctacg atgaatcagc tttttgcagc ctatgcacaa ggaaaacagg
    77881 caaaagaatt agccgtagtt ttaggtgaat ctgctttatc tgatgtagac aagatctatg
    77941 cgaagtttgc tgagcggttt gaaaaagaat atgtcaatca aggattctac acgaaccgtt
    78001 cgattactga aacacttgat ctagggtggg aactgctatc gatgttgcca agaaccgaat
    78061 taaaacgaat caaagacgac atgctggaca aatatctgcc agaagggaag tgagttctga
    78121 tggcacgatt gaatgtgaat ccgacccgca tggaattgac tcgattgaaa aaacagttga
    78181 caactgccac aagagggcat aaattattaa aagataagca agatgaactg atgcgtcaat
    78241 tcatcctgtt gattcgaaag aacaaccagc tgcgtcaaga aatggaagag tctatgacag
    78301 aagcaatgtc tgattttgta ttggcaaatg cttcgatcac ggaacctttc atcgaagaat
    78361 tatttgtttt gccggcggaa aacgttgatt tgtctatcgt agacaaaaat atcatgagtg
    78421 taaaagtacc tgtgatgaat tttgaatatg atgaacagct gacagacaca cctttggaat
    78481 acgggtattt gaattccagt gccgaactgg atcggtcaat cgatcggttt actaccctgc
    78541 ttccaaaact tttggaactg acagaaatcg aaaaaacttg tcaactgatg gcgagtgaaa
    78601 tcgaaaagac acgtcggcga gtcaatgcat tagaatatat gacgatccct caattagaag
    78661 aaacgatcta ttatattcgt atgaagctgg aagaaaacga gcgcgcagaa gtaacaaggt
    78721 tgatcaaagt aaaaaatatg ggtaccactg actaagtggt atcttttttt aaaagaggaa
    78781 aacgatgatt aaacaaagca aacaaataaa gaaacgtttg ccggctgttc agcttctcgc
    78841 attaggattt tttctcctga ttttagttgg cggcggccta cttaccctac cattttttag
    78901 taatagtggg catgggacaa attttatcga tgcgcttttc actgcaactt ctgctgtctg
    78961 tgtaacggga ttgacaacat tgaatacagc agagcattgg aacagtgctg gtcaattttt
    79021 gatcatgctt ttgattgaga tcggcggtct tggttttatg atggttccga ttctatgctt
    79081 tgcattgata aagaagaaag tcagtctcag cacacgtatt atattaaaag aagcgctgaa
    79141 tctagaagaa gtatcaggtg tgatgaagct catgctttac atcctaaaat tggcctttgt
    79201 gatccaattg attggtacgg ttgctttatc ttttgtattt gtgcctgaat ttggctggtt
    79261 gaaaggtatc tggtacagtt tgttccatgc aatctctagt ttttgtaatg cagggtttga
    79321 tttgttagga gacagtttag ccaatcacca gcaaaatgtt tatttgatca tggtggtatc
    79381 tgctttgatc atttctggtg ggttaggctt catcgtatgg cgtgatttac tggaatatca
    79441 tcagaaaaag aagatgacga ttcattcaaa aatcgcatta accgttacag gtaccctttt
    79501 attaggcgga ttcgttgtgt tctttttcac agagcgcaat ggggcaacgc tagtggaagg
    79561 gaatatgttt caacgattgg caaacacctt ttttatgagt gtgacaccta gaacggctgg
    79621 atattattca gttgattacc tccatatgag ccatgcaggt ctgattttaa cgatgttttt
    79681 gatgtacatc ggcggaacat ctgggtcgac ggccggcgga ttgaaaacaa ctacgttagg
    79741 tgtgttgctg atccagatgc gttcgatgtt gaaaggacgt acgagagcgg aagcatttgg
    79801 ccgtaccatc cgacaaggcg cagtgttgcg ggcacttact ttattttttg ttacgttgac
    79861 gttgtgtgta gtcgccatca tgattttatc ggtgactgaa acgataccta aaacttctgg
    79921 catcgaatat attgcttttg aggtcttctc tgcgtttggt acagtaggtc ttacgatggg
    79981 attgacgcca gacttgactg caatagggaa attgatcatt atagcgctta tgtacattgg
    80041 acgagttggt gtattgactg tggtcttctc tctgatgaca aaagcacaaa gaacacaatc
    80101 aaaatacaaa tatccagaag aaagtgtcat gattggataa tttcatcttc tgacagaaac
    80161 ctagtgattt agtaaaataa gaaaataaaa taatttttct tgcttcttgg atactttaag
    80221 tgcaaaatgt tcgtttattt tttgaggcac tacccgttgt tgaacctcgg gtagtgcctc
    80281 ttttttattg aaaggaatca ataagatttg attcctttat ttatcaatag gttataattc
    80341 atattttttt attttttctt ttacgatact tagtccagaa gctaaaattt caaggttatt
    80401 agaggatagg gaaattcgaa cgaatgcatc tggttgcgta cgtgtagtaa agcgtctgga
    80461 atgataaagt cggataccgt tagcaagaaa gtcattctca attatcttag ggtcaatctc
    80521 aggatcaact ggaagaattc gatagtaagg gacacgattc gttggttttt ctactttgaa
    80581 aagagaatca aaaagctgat tggctctttt tgtaagactt aatttagttt ctaagatcct
    80641 atttgcttca tttgaatgga ggatttgagt gatgacttcc acatctaatc cagaagtttt
    80701 cacatttata ttaaaaattg cttgttctat cttgctttgg acatgtactg gaactacaag
    80761 ataagcaact cgcaatccag aacaaataaa ttttgtcatt ccagctaagt agattgtttg
    80821 gttaggtaat aaattttgga aaggaggaat gatcgtatgt tgatagtaag ttgttaaaaa
    80881 tgaatggata tcatcttcaa taacccatag accttctttt tcaatcactt cggctaattg
    80941 ctctcgtctt ttgtgagaga tttgaaaccc tataggatta ttacaagaag gcataagaaa
    81001 gacaccatga atcttctttt ttctacattc ctgaatcaat atatcaggtc gcattccttg
    81061 ctcgtcaaaa tcaattggaa cgatctctaa atgatataac tgagccaatt caatgaaatt
    81121 agcgtatgta tatcggtctg ttgctattct atcacctgga gagaaaagtg cagaaagtgt
    81181 gatagccaat ccattttgaa caccggaaac aatagataga gattctaagg acggaatgac
    81241 tccttgagtt tttaaccaat ttgctgcagt agtcaattga aaatttgtgc ctttgggatc
    81301 ttggtaatta agcaaaccaa caagatttgg gttattacta gttgattgaa taaacgggac
    81361 aacgaattta ttacattctt caaaagaact aaccagacca aaatcaatga tatgttcggt
    81421 tacttcattg gtagagatgg tgatggactc aaagacattg ggagaaataa atgtgccact
    81481 tccaatattc gtatacagca aacctttctc aattccatat ttataagcct tgccaacggt
    81541 agtaaaattt aaatctaaat aatcagctag ctctctttgg gagggtaact gagtgttttt
    81601 ctgtaattta ttctttaaaa tatcttgttc taattgttga atcaacgatc gataataagg
    81661 acgcttcaat ttttgtttgt ctggtcgcca agttaacggg taattgtcat aagaattaat
    81721 aggcattttc tccactcctt aaaattgtat accatacaat tttaccattg attgtattga
    81781 ttttagaagt taatcttttg tgaggaggga attgtctatg aaaattatta attttgagga
    81841 agtagtagct tcttttagtt ttgaagaagc gattcaagta atgaaaaaat gtttttttga
    81901 ttatgaaagt ggtaaaatca gccaaaatcc tcgattggtg gaaattttac ctgacggaaa
    81961 aggcaaaaat atgtttgcga tgatgcctgc ttatttgggg gagaacagat attttggcac
    82021 aaaagtcatt accgcttttc cggataatca tcagtatcat ttaccttctc atttaggaga
    82081 gattttcttg tttgatgctc aaaacggact acccaaagca ttgataaacg caaatgcagt
    82141 cacctggatt cgaacagctg ctgtatctgc gctggcaaca gattacttag caaatccgca
    82201 tgcagaaaca cttgctttaa ttggagctgg tcaacaagca ttgtcgcatt tgactgcgat
    82261 ttctaccatt cgtcccatca ctacagtgtt tgtttacgat attttagaag aaagacgaaa
    82321 tacttttatc gctaaagcta aaaaacagta tcctaaaata acgtttataa atgcaatatc
    82381 agtagaagat gcagtacgtc cagcggaaat catttgtacg ttgacctcta gtaaagaggc
    82441 atttcttcaa aaagagtggg taagggaaga cgcacatatc aatgctgtgg gcacatttac
    82501 tcctgataca agagagataa gtacatcgtt gatggaaact tctcaaatct atgtagatga
    82561 ttactcagct gccttaacag aaagcgggga cctgcttata gccatggcag aaggagattt
    82621 agaggaatct tgtattgttg gtacattagg cgaattagtt tctgagaaaa aaacatttta
    82681 taaaggagaa tcgaggccga cgattttcga cgcagttggt ctagctattg aagatctttg
    82741 ttgtgcagaa tatatttata acaaattaga gaaaggggct ttaaaatgaa cttagattat
    82801 tacgtagttg atgcatttgc agatgaggtg ttcaaaggaa atccagcagc ggtttatgtg
    82861 ctagaagaat ggctgccaga aggtacgatg caaaaaattg ccattgaaaa caatttatct
    82921 gaaacagcat ttacagtgaa gaaaaaccaa gaatttgagc ttagatggtt tacgccagat
    82981 cgagaaatcg atctttgtgg tcacgcgaca ttagcaacag catttgtttt atttaactat
    83041 tacaaaatac ctgatgaaac gattaaattt tctactcaaa gcggtaatct atttgtgaca
    83101 agaattaaag attattatta catggatttt cctagtatta tgccgaaaaa agtgccgata
    83161 ttgtctgaat atgaagaagc gattggggct aagattaaag aagcctactt agcacgtgat
    83221 ttatttttcg tattagaaga tgaaaaaacg gtggctaaat tgcagccaga ttttacagct
    83281 atcaaaaatt ttgaattagg aataggagtc atcgtgacag cagaaagtgt gcaaaaagac
    83341 tttgtttcta gaaccttctt tccaaaatta acaatcaatg aagatccagt atgtggatca
    83401 gcacattcta atcttattcc ttattgggca gaaagaatga ataaaacaaa attgtcagct
    83461 tatcaaatgt catcaagggg cggggatcta gaatgtgaat taaaagaaga tcgtgtgata
    83521 ataggaggaa aagcagtttt gttttctaaa ggtacctcgt ttatttgatt tctttcaaat
    83581 gaattaaaaa taaattggtg gagagtggca accttatagc tacaatggtt gttaaaaaaa
    83641 gacgcaaact ttttcaattt aatgaaaagt ttgcgtctca ttttaattat tggtgtttgt
    83701 tttttattca atcaagagta aaatgcccca tactaactat cctcggatga cttcgatttt
    83761 ataaccatca gggtcaatga caaagtagta agaaggcgca gtgccaggta atccttttaa
    83821 gtcagtaatc tcaagaccag cagctttatg ttgctcgtgt aatttttcta gatcatcagc
    83881 tgctatagcg atatgaccat agccgtctcc tagatcatac gcaccatgat catagttgta
    83941 agtcaactct aattcatagt catccccagg aagtgtcaaa taaacaagtg taaatttgtt
    84001 ttctggaaaa tcacggcggc ggctttcttc aaaaccaaat gccttttgat aaaattcgat
    84061 tgatgcttca agatctttca ctcgaacaca tgtgtgagcc attttcatag attcatctct
    84121 ccttttcctt ttactcaatc ataacaaaaa gaagtaagga aatagttgat ttgtgcttgt
    84181 tcatgagaaa tttctcatgt aaaatggata gaaaataaaa ctgttaaggt ggaaactatt
    84241 catggataaa ccaatttttg gtgaaaaaaa gcaatttgct gattatcaaa cccgttatgc
    84301 agcatatatt gtcatagaaa gagatcagca gattgcagta atcgaggctc caaatggtgc
    84361 tttttttctt cctggcgggg aaattgaagg agaagagacg aaagaagaag cgattgtccg
    84421 tgagctgata gaagaaatgg gaattgtggc agaaatttct tcttatctgg gagaagctga
    84481 tgagtatttt tactcgaatt atcgtgcaac ttattattat aatccaggat atttctttgt
    84541 tgctgattct tggaagcgta taggagaacc aactgaaaag accaataaaa tttggtgggt
    84601 gagccctcaa gaagcgcttg tgaaattgaa acgtggtagc caccgatggg cagtcgagag
    84661 atggatcgaa aaaaataaaa actgaaagaa agcgagtaga tcagctttct ctcagttttt
    84721 ttatttatta cagtacatat tttttgattg cttcagctac accgtgctcg tcgtttgatg
    84781 aagtgatgac atttgctgct tctttgacaa gagaaacggc atttcccatt gctactccta
    84841 gaccagcata ttcaatcatg gataagtcgt tctcgttatc tccgatagcc atgatttcat
    84901 cttgatcaat accaaggtgc tgtgcgagat tcgcaactgc cgcaccttta cttgcttctt
    84961 tatttagtac ttcgaagtaa tagggcgcac ttttgaccgt tgtgtattta tcacggaaag
    85021 tttgcggtaa acgcgcaatt gctgcatcta aaatttctgg ttcgtcgatc atcatcattt
    85081 tgacgatgtt catgtctggt gtcatttctt caggtgttcg atattttagc ggcatcttga
    85141 ctaaacttgc ttcgtggatc gtataagcgc tgatatctcg attaggcgtg tagatcgctt
    85201 tgtcatcgat cgaatggaga tgactgccga cacggcgtgc catcacttcg atctctagga
    85261 aatcttcatg tgtcagtccg tgacgggcga tgattttacc tgatttcgtt tgttgtacga
    85321 gtgccccgtt ataagtaata acgtaatcat tatcttgaaa aaggttcaac tcgtttaact
    85381 gttcctggac acctggtaag ggacggccag tgcataaaac gatcgaaaca ccttttgcaa
    85441 cagcagcggc aatcgcttct tttacttctt ttgttacttc tcttttctca tttaataaag
    85501 taccatcgat gtcgatagcg actagtttga tagacataat ttcctccaat atattttaat
    85561 ttatttcaat caatgcgcca ttacggatat ggctggcaaa ttcttgataa gtttcgtcaa
    85621 ataaatcata atgatcacgc aaggacggat caaccatttc ttttggaaag aaaaatcgct
    85681 catctccttg ttcttgtccc gctaatgcag caacaagctg actaacctgt gataattcta
    85741 tcaaagttcc gtcatttcgc aaaatctcga tttgtgtgcg atgtctgcct tgttctgggc
    85801 gataaaaatc ataaggtaga tcgtagctag aattcacagc agtgtaataa acaggattat
    85861 atccgacctt ttctactaac aaagtgagtt cttggactaa ttttgaatcc cggttgccag
    85921 aaaaagtagc agatttcagt ggtttacgat tcaaaaaacg tttagctaaa tcatttaaaa
    85981 taggatcagc agattcagac cattgagtaa agtaagtgcc caagacccca tcatcaagtt
    86041 tgaggtattc ttctaaagta aagcttccgt caagaaatgg cagaagtaat tgagaatgga
    86101 gttcaaaact gctggcatct tcttgataca actcgtgtgc gcgatgaagc agatgctcca
    86161 aaattacttc cataccacgg gaaacaggat ggaagtacac ttgcacatac atttgatatc
    86221 ggctaacgat ataatcttcc actgcatgca tgccactcat ggaaaaagcg atcccgcctt
    86281 cataaggacg aatcacacgt aatattcggg taagatcaaa tgttccatat tctgttccag
    86341 tgaaataagc atcccgaagc aaatagtcca ttcgatctgc atcgatctga ctagaaatca
    86401 tttggacaac ttgtgggttg gggtaagttt tttggatcac actagctacc ttttcaggaa
    86461 aaccttcttc tactcggtta agaatctgat acacttctgt ttctggagaa gtgatgatct
    86521 ctacagtgat ggcttcatga ttcgtatgga agatatgttc aaatgtatga gagtaaggac
    86581 catgaccgac atcatgcaac agtgccgcac ataaagtcac cagccgttcc tgatcatccc
    86641 agcctccgtt gcctattttt tcttttgaaa aatttcgaga aaagatatcg cagattcgtc
    86701 ttgaaatctc ataaacgcct aatgaatgag taaaacggct atgttctgct ccgtgaaaag
    86761 tgaaagaaga agtgcctaat tgtttaatgc gtcgtagacg ttggacttct ttcgaattga
    86821 tcaaatctaa gattacttga tgctggacat ggatatagtt atggactgga tcacgaaaaa
    86881 ctttttccat aggcagcatt tgatatttat aaggggttgt cataatgtag ctcctttatg
    86941 ttattacgtt gttccattct ctggatttgg ttgttccatt gctccagctg gatttctttt
    87001 tttagccagt cggtagaatc ctgtaaatca cttgcagaat acagcttttc aaaagctttt
    87061 gcaaatgctt ctttgacttc ttttacaaaa aggggttggt caagcagttc ttcaagtgtt
    87121 gccattgtag caggatccac tgcaggatag ccatttgtac caaagtcttc ttttaaagca
    87181 gattgataaa atcgcttcat gacttgcccg cgtttttcct gattaccgtt gacacttaag
    87241 tacatcataa cagaaatccc atttttgatc cgacgctgag cgataccggc aaattttttg
    87301 ccatggatgc ttaaatcata agttccagga caataagaat gggtgatttc gaatgcttgt
    87361 atcggtgcct ttggaaaagc gtatttagtc aataggagca tttgctcgta agcgtcatct
    87421 atggttattt tttttgtgtc actttggggg aaaatcaaag aaatattcaa aattccttca
    87481 tctgatacga tccctaatcc acctgaattt ctgatcactg gagcgtaacc tgcatctttc
    87541 agtgtttgga tcccgtcact tagaaaagga gttcgaacat ccttcatacc taagatgact
    87601 gtgcagtcat attgccagaa atgtaaaaag atttgctggt gttctttaga atattccgtt
    87661 aatatatctg ttaatgcaaa aggggaaaag tcgttttttt gataaatgtg ctgatctagt
    87721 cgaatcgcag ggttcattca accggctcct ttgtataaat tcatattttc tacaatatta
    87781 tactctaaaa tcaaagagtt gttttggaaa aaaggttttc tgtaaaaatg gacaagttgg
    87841 ttgacaaaac aaaagaaact aggaacaatg tagctatgag aagtaaagga gaatgaataa
    87901 tggaattatc acaaggaaca ccgatttcaa tcaaattgcg tacaaaagta aaacagcaag
    87961 gggaagtgca agatttttat tttgatttga aagggcaaat ggtgacaatt ggcgatacgc
    88021 tgtacatacg ttataaagag attcaggagg agacgggcga tgagattcct gtaacgatca
    88081 aattagttcc agatggtcat gtacagctga tccgtgcagg agaaatgcgg atgcgtttga
    88141 aatttggcta taaagaacgg ttagaaacat cctatcgaac accatacggt atgatccaga
    88201 ttgctacttt tacgaaagaa ctgcatgtta gtttgaaaga ccgtcccaca gcagggaagg
    88261 ttcgaatcga ttatgatctg ttcatgggac cggaaaaaat cggcgaatat tatttgacct
    88321 tggattttac agcgtaaata taaaagaaaa gtttgatttt ttgtgtctga ttttgtatga
    88381 taaggagtag actgtgaaag gacgtgtcct gattggaaat tagtgtattt gaaggtgcaa
    88441 acaaaagcga attatcaatg atcgaagtag cacacgcgat cttagaacaa cgtggcgatg
    88501 tcatggattt ttctgattta gctaaccaga tccaaaacta tcttgggaaa tcagacagtg
    88561 aaattcgtga ttcactcgca caattttata ctgacttgaa tattgacggc agctttatct
    88621 cattagggga taatcgttgg ggcttgcgtt catggtatgc tatcgattcg atcgatgaag
    88681 aagtaaacca tggaatggac gaagaggatg aagatactcc acgtcgccgt aaacgcaaga
    88741 aagtcaacgc ctttatcaat gatgatgaag acgcgatcga ttacaatgac gatgacccag
    88801 aagatacaga tctgacagaa gaagatgacg atgatctgtt tgatgacgat gatgatgaag
    88861 atgaagaaat cgctgcttat aattctgact tgcaagaaat cggagcagat gacccgacag
    88921 atgatgaaga agacttgcca ggaaatatcg aagaagattt aagtatcata gacgaagacg
    88981 atgatgatga agattatgaa gaggaagaat tttctgactc tgaaaaagaa taaacattat
    89041 tttcttacga gaggttgtga cagagacgat cagcctatca gaataaggag gtgtgacacg
    89101 atttttgtca caccttcttt tttgtatata aaaatcccaa gtaaatacat aaaaaataaa
    89161 aaaattgaaa cttttagcgc accttgtacg tcatattaag tgaggcagaa aggagtggag
    89221 aatgattttt actggatata agaaaaaacg gcagatcgaa aaataccgtc acctgctgaa
    89281 tggactcatc gaaactgatt atcaaaaaat gttccgtatc acgatgaatt acgtacatga
    89341 taaagaagag gccttagatg tgatgcaaga tagttttcat aaagccctga actattttga
    89401 aaaagaaaaa gagatcgagc attttagtgc atggttttat cggatattga tccgcacggc
    89461 attagatagt tggcgcagac aaaaaaggac gcctgtggac ttatttgaaa ttcaagatat
    89521 cccccaacag ttacctttag aaacttccgt tgcagagctc catatgattt tagataaaat
    89581 agacagtccg gaaaaagaga ttctgatcct ctactttttt gaaggatttc gtttgaaaga
    89641 aattgcgact atcttggata tgaatgaaaa cacagttaaa acgaaaatgt accgctcatt
    89701 gaatgcttta cgtcaaatcc tagaatgaag gagagaagag tgccatgtat tcccaaaaag
    89761 aaaatttaaa aaaactaaag aaaacttata aagaacaagc aattcccaaa gggcttaaag
    89821 aggagatccg ccagcgtttt attatcgaag agcaatcatt tataaaagca aagcggagaa
    89881 agagacgtct ccaagggttc ggagtatctt tggctatcgt aatgattaca acaagtagcc
    89941 ttctttttaa tagtcaagtt cgaagctttg cagaagattt acccatctta ggatcagtca
    90001 ttgaattgat cttaggcgaa cgctttactg atcgatctga aaaaatcgat attcaggtac
    90061 cgaagatcaa tacacaaaat gagaaagaaa ataaaacaat tcatggatta aatcaaaaat
    90121 actttcgcga aggacaagca gattttgaaa aagctgaaaa agaatatgga aattttgaaa
    90181 cggatcatta ccaagttttg ggagattatc agaaaatcgt agacgataac cggtttctcg
    90241 tgattgaaag gcagatcacc caaacagcag cagatagcca tgttgaaaaa agatacgaca
    90301 caatcgacaa gaaaaacagt gtccagctct cacttccact tttattcaaa gatgacacct
    90361 atctatctgt tttgacaaaa gaagtcaaac ggcagatggc cgaacaagtc aaggaagatc
    90421 catctaagta ctattggact gagcaagata ttcaagaagg gacgatagaa aaaccaacac
    90481 ttgttacgcc tacacgaagt ttttatttga acaaagagca tcaattagtt ttgacttttt
    90541 ctcaatacga aattgctcct ggttatatgg gtacaccaga atttgtcatt cctaagtccg
    90601 tgacaaaaac gattttggca tcggaagatt atttggatca ttagacgaga agtagttgcg
    90661 actagcagtt tcaattttca agtaagtaca agtaaataat aagaagagaa aaagagaaag
    90721 aagagatata gtgaaaagaa attatttagt tatcagtatt attgctttat ccgtgctttt
    90781 gtttttcgaa attacttcgg tggcctcctt gatcaccgaa gtaaaaggac aaacacactc
    90841 ttcggagcat tcgtcacaat ctttcaaaca atcagaacaa tcaaccatta aaagccaatc
    90901 aactgaaaca gctaacgtca aagaagccat tcaagaatca gcggaaaagg tacaaagtca
    90961 gtcatcacaa tcaacacaag acagtacaaa aacgagccga gatccggctg tcaaaagcgt
    91021 cgcaatcagc tttgatgatg gaccaggagc gaccacaaca ccgcagcttc tgcgaatctt
    91081 aaaagaaaaa aacgtgcatg ccactttttt cgtcttagga gaaaatacgg cgcagcatcc
    91141 tgaaatcgtg aagcagacag ctgaagcagg gcacgagatt ggcaatcaca catacgatca
    91201 tcagaatctg gccactcttt ctgcccagtc gatgacggag gaagtgacga aagcagacac
    91261 tgagatcaaa aaagtcactg gcaaaacccc cacttttgtt cgtccgccct atggttctgt
    91321 cacgaatgta ggagcaacga tcatccagcg accgatcatc gaatggtctg ttgattcaga
    91381 agattggaag acaagaaatc ctgatttgat tttgcagaag atccaagcaa cagtatacga
    91441 tggggcaatt attttattcc atgatatcta tcctgaaacg attcgtgccg ttcctcaagt
    91501 gatcgattat ctgaaagagc aagggtatcg catcacgaca gttggggatt tattagggca
    91561 tccaacggct gtcgagaact attatggcag aaacgatcat cggccagttc agtaagtgag
    91621 acaagtatct ttaataaata acacatttta ataagtagtt gaacacataa ctaccttact
    91681 tgcaaaggct taacaatatc tatacaggta caacaaaaaa ctgtccacca attttctttg
    91741 gcggacagtt ttcacttaaa aataaagaag caactattcg taaattatgc taaaatagca
    91801 gtagaacgcg tcctgaggga atcgaacccc cgtctcaaga accggaatct tacgtgatat
    91861 ccactacact aaggacgcaa gcactgggat aattgtaact aaacagataa aaaattacaa
    91921 ggggattgga caaaaaaatg aaatttgagc aaaatttttc acaaaaacag cagcagacac
    91981 agaaactagc catgacgcaa cagttgcaac agtccatcca agttttacaa tataacagtg
    92041 aggagctgtt ggcattcgtt gagaatcaag caatggaaaa tccattggtg gaagttgttg
    92101 agccggaatg gcagccagat tacataaaag cttcttcatc ttcttatgaa ggagaagaga
    92161 caaattacct aaatcagatt cctgatacaa aagggtcttt atttgattca ttgatcgaac
    92221 aagtccattt gaattaccga gatacttttt tgaggaaaat cgttctttat cttgtagaat
    92281 acatcgattt gaacggattt ttgacgatta gtttagaaga agccggaaaa gagattggag
    92341 ctacgcctat ccaaatgctc gatgcgttga ctctgattca gcaattagaa ccagctggag
    92401 taggtgcacg tagtttgcaa gaatgtctca tgcttcaaac agaacgagat gattatgcgc
    92461 cggaattagc ttatatcgtg ttggaagaat gttttgagga actggtggag cgaaaatgga
    92521 aagaaatcgc acaacgtttt tctgttgatc tacatgctgt tcagcagata ttcgactatt
    92581 tacaaacgtt gagtccaagc cctggccgga ttttcgaccg tagcagcgaa ttgtacatta
    92641 ttcctgatgt ccgggtatta gtggacgacg ataaaaatgt acaagttatc tcaaaccgaa
    92701 aaaatcagcc aaatatacgc tttcaagaga gttacttcaa acaaatgtca caacaagcag
    92761 ataaagaaac tgaaaattat ttaaaagaac ggaaacagga attcgaatgg ttgaagaaaa
    92821 cgatcctaca acgtggggat acaattttgc gggttgctca agtcattgtt tcccggcaaa
    92881 aagctttctt tatcgacaag gaacgtccaa tcaagcctct tacgttaaag gaagttgcaa
    92941 ctgagataga tgtgcatgaa tccacggtca gtcgtgcagt caacgggaaa tatttggaaa
    93001 cagacttcgg tgtatttgaa ttaaaaaaat ttttcactac acgaattcct acgaatagta
    93061 cagaacagac agaagacctt tcagcagata cagcgaagaa aaagctgcag gaattagtcg
    93121 atcaagaaga caaaaacaag ccgttgtctg accagaaatt ggttgaattg ctgaaaaaag
    93181 atgagatagc gatctcaaga cgaacagtag caaaatatcg tgatttatta ggaatcccga
    93241 gttcatcaaa aagaaaacgt tatgataact aatcagtcaa aagactagaa aaagtatttc
    93301 actttttcta gtctttttag ttgaaaaacg agagcaaaac tgttagactt acagtcgtga
    93361 ggttgagatt tccctttatt gatgtgaaat tcgaatagtt aatttctttt tttatcgtat
    93421 atgggtcgtt ttaagtctac attggacgta aagtgtccaa ctaaggagat cgctatgctg
    93481 gatgaaataa aaatgattga atctgttgca ccagatatta tcgaagtgtt gcaagaacgc
    93541 tataaaattt tacgaaatat ctattggatg cagccgattg gacgtcgaag tttatcggaa
    93601 agtatgggga tcacagaacg agtattgcga acagaaacag atcttttgaa aaatctgaat
    93661 ttgatcgaca cctcaaaaag cggtatgacg ctgacaacta agggcgaaga agtttatcaa
    93721 agccttgaaa acttcatgga tcagctttta ggtacgcatc aaaccgaaca acagttggca
    93781 gaatattttg gtaaccaacg ctgtatcgtt gtttcaggaa acagcgaaga gcagaccaaa
    93841 gtggctgatg cattcggcga agcgctgagc gaagccctag accgactact tccagaaggc
    93901 gagaatatca tcgctgtgat gggaggaact actatggctg tggtagccga acaattgtct
    93961 aatctggaaa ataagaaacg gcataacctg tttgtccctg caagaggcgg gattggtgaa
    94021 gcgataactg tacaggcaaa ttctgtcagt gcaagaatgg ctgctaaagc aaacggtaac
    94081 caccgtgcac tttatgttcc ggaacaatta agtctggcaa cttacaattc tttactcaat
    94141 gagccatcta tccaagaagt cttaaacttg attagtgaag cgaattgtgt tattcatagt
    94201 attgggcgtg cattacacat ggcagcacgt cgtaagatga ctgaaaaaga attagtcatg
    94261 ctgaaacaag caaatgctgt tgcggaatct tttggctact ttttcaatga aaaaggtgaa
    94321 gtcgtttata aggtccctag aatcggcata gaattgcaag atttggaaaa agtcccgatc
    94381 atcatggcaa tcgcgggcgg aaaatcaaaa gctaaagcaa ttcgagctta tatgaaaaat
    94441 gcaccaaaac aaacgtggct catcactgat gaagctgctg caaatgagat tttaaaaggg
    94501 gtaacccttt aaaataaata tttttttgat tttcataagg aggaaatctt aaatgacagt
    94561 taaagtaggt attaatggtt ttggacgtat tggacgtcta gcattccgtc gtatccaaga
    94621 tgtagatgga atcgaagtag tagcaatcaa cgacttgaca gatgctaaaa tgttggcaca
    94681 cttgttaaaa tacgacacaa ctcaaggacg tttcaacgga acagttgaag ttcatgaagg
    94741 ttcattcaac gtaaacggaa aagaagttaa agtattagct aaccgcaacc cagaagaatt
    94801 accatggggc gaactaggcg tagatatcgt tctagaatgt actggtttct tcacttctaa
    94861 atcagcagct gaaaaacatt taacagctgg tgctaaacgc gttgttatct ctgctcctgg
    94921 cggaaacgat gttccaacaa tcgtttataa cacaaaccac gaaacattaa ctggtaaaga
    94981 aacagttatc tcaggtgctt catgtactac taactgttta gctcctatgg ctaaaacatt
    95041 gaacgacaaa tttggtgttg ttgaaggatt aatgacaact atccacgctt acacaggtga
    95101 ccaaatgact ctagacggac ctcatcctaa aggtgacttc cgccgtgcac gcgctgctgc
    95161 tgcaaacatc gttcctaact caacaggtgc tgctaaagct atcggtttag taattcctga
    95221 attgaacggt aaattagacg gagctgctca acgtgttcct gtaccaacag gttcattaac
    95281 agaattagta acagttcttg aaaaagaagt aactgttgac gaaatcaatg cagcaatgaa
    95341 agaagcttca aacgaatctt acggatacaa cacagacgaa atcgtttctt cagatatcgt
    95401 tggtatgact tacggttcat tatttgatgc tacacaaact aaagtaatga cagttggcga
    95461 caaacaatta gttaaaactg ttgcttggta cgacaacgaa atgtcataca ctgcacaatt
    95521 agtacgtact ttagaatact tcgctaactt ataagataga caaacgtaca agtgtaaatt
    95581 atagacatgt acatttaaaa gcggggaagc aatcgcgctt cttccgcttt ttttgataat
    95641 aagtttattc aggaggaaat aaaatggcta agaaaacagt gaaagatatc gatttaaaag
    95701 acaaaaaagt tcttgtccgt gttgacttca acgttccttt gaaagacggc gtgatcactg
    95761 acgacactcg tatcaaagca gcattgccaa caatcaacta cgttctagaa caaggcggaa
    95821 aagcaatcct tttctctcac cttggacgtg taaaaacaga agaagataaa gaaggaaaat
    95881 ctttagctcc agttgcaaaa cgtctaggcg aattattagg taaagaagta acattcgtac
    95941 ctgaaactcg cggagaacaa ttagaagaag caatccgcaa catgaatgac ggcgacgttg
    96001 tcgtattcga aaatacacga tttgaagata ttgacggtaa aaaagaaagc aaaaatgata
    96061 cagaactagg taaatactgg gcttcattag gcgatgtatt tgttaacgat gctttcggta
    96121 cagctcaccg tgcacatgct tctaacgtag gtatcgcttc aactggtatc ccaacagttg
    96181 ctggattctt gatggaaaaa gaaatcaagt tcatcggtga agcagtagaa gaaccaaaac
    96241 gaccaatgat tgcaatcctt ggtggcgcaa aagtttctga taaaatcggc gtaatcgaaa
    96301 acttgattcc taaagcagat aaaatcttga tcggtggcgg aatgacttac acattctacg
    96361 aagcaaaagg aatcaagatc ggtaactctc tagtagaagc tgataaagtg gaactagcaa
    96421 aagaattaat cgaaaaagca ggcgacaaac ttgtcttgcc aatcgacaat gtctgtgcac
    96481 cagaattttc aaatgatgtt gaaacacaag taatcgaagg agacattcct gatggtttga
    96541 tggctttaga catcggccca gcatcagtaa aattatttgc tgatacatta caaggtgcaa
    96601 aaacagttgt ttggaacgga cctatgggtg tatttgaaat gagtaacttt gctaaaggta
    96661 caatcggtgt ttgtgaagca atcgctaact tagaaggcgc aacaacaatc atcggtggcg
    96721 gagactcagc cgcagcagca gaacaattag gatttgctga caaattcaca cacatctcaa
    96781 caggtggcgg cgcaagcttg gaattgcttg aaggtaaaga attaccagga ctagcagcaa
    96841 tcaacgataa ataaacgacc aagtttgctc aattctgacg agtaatcgaa caaaaggtga
    96901 agggagtttt catgactccc tagccatttt tcaataaatt aaggagtgtg ttcctcaatg
    96961 cgtaaaccta ttatcgcagg taactggaaa atgaacaaaa ctgcatcaga agcaaaagaa
    97021 tttgctgaag cagtaaaaaa caaaatccct tcaaatgaca aagttgattc agtcatcgga
    97081 tctcctgcat tattcttaca agaattaatg acatcagctg aaggtacaga actaaaaatc
    97141 tcagcacaaa actgctactg ggaaaactca ggtgcgttca ctggtgaaac ttcaccagca
    97201 gctcttgctg atctaggtgt tcattatgtg atcatcggac attcagaacg tcgtgaatat
    97261 ttccatgaaa cagacgaaga catcaataaa aaagcgaaag ctatctttgc aaatggtatg
    97321 acaccaatcc tatgctgtgg cgaatcttta gaaacctatg aagcaggcaa aactgctgaa
    97381 tggatcgaag gacaaattac agctggttta gctgatcttt cagctgaaca ggtgtcaaac
    97441 atggttattg cttatgaacc aatctgggca atcggtactg gtaaatcagc tgacgcacaa
    97501 atcgctgacg aaatttgtgg agttgtacgt caaacagttg aaaaacttta tggaaaagaa
    97561 gtatcagaag cagttcgtat ccaatacggc ggttctgtaa aaccagaaaa tattgctgaa
    97621 tacatggcaa aagaaaatgt tgacggtgct ttagtcggtg gcgcaagctt gcaagcagat
    97681 tcattcttgt cattgttaga cgctgtaaaa taattgttga aaatttgcga aaaatgcaag
    97741 aaatgtttgc actaatgagc aaaattaact aaaatcgtat atgagggaaa tcccttagga
    97801 aaaaacaaac tcaaaggaga gacaaaacat gtcaattatt actgatgttt acgctcgcga
    97861 gatcttagac tcacgtggta acccaacaat cgaagtagaa gtatacacag aaagcggagc
    97921 ttttggccgc ggaatggttc cttcaggtgc ttcaactggt gaatacgaag cagttgaatt
    97981 acgtgacgga gacaaagctc gttatggcgg taaaggtgta actaaagctg tcgacaacgt
    98041 aaacaacatc attgctgaag caatcattgg ctacgatgtt cgtgaccaaa tggctatcga
    98101 caaagctatg atcgctttag acggaactcc taacaaaggt aaattaggtg cgaacgctat
    98161 tttaggtgtt tctatcgctg ttgcacgtgc agctgctgac tacctagaag tacctttata
    98221 ccactaccta ggcggattca acacaaaagt attgccaaca ccaatgatga acatcatcaa
    98281 cggcggatca catgctgata actcaatcga cttccaagaa ttcatgatca tgcctgttgg
    98341 cgctccaaca ttcaaagaag ctctacgtat gggtgctgaa gtattccacg cattagcttc
    98401 aatcttgaaa gctcgcggat tagcaacttc tgttggtgac gaaggtggat ttgctccaaa
    98461 ccttggttca aacgaagaag gttttgaagt aatcatcgaa gcaatcgaaa aagctggcta
    98521 tgtacctggt aaagacgttg ttcttgctat ggatgctgct tcttcagaat tctacgacaa
    98581 agaaaaaggt gtttacgtac tagctgattc aggcgaaggc gaaaaaacaa ctgacgaaat
    98641 gatcaaattc tacgaagaat tagtttctaa atatccaatc atctcaatcg aagacggatt
    98701 agacgaaaac gactgggacg gattcaagaa attaactgac gtattaggcg acaaagttca
    98761 attagttggt gacgacttgt tcgtaacaaa cactcaaaaa ttatctgaag gtatcgaaaa
    98821 aggaattgct aactcaatcc ttatcaaagt gaaccaaatc ggtacattaa cagaaacttt
    98881 cgaagctatc gaaatggcta aagaagctgg ctacacagca gttgtatctc accgttctgg
    98941 tgaaacagaa gattcaacaa tctctgatat cgctgttgca acaaacgctg gccaaatcaa
    99001 aactggttct ctatcacgta ctgaccgtat tgctaaatac aaccaattac tacgtatcga
    99061 agaccaactt ggtgaagttg cagaatacaa aggtttgaaa tctttctaca acttaaaaaa
    99121 caaataattc ttttctaatg aagatacatg atcgactatt gaaagatagt cgagtatgat
    99181 cacttagtta agtaatcgaa ctctctactt gctgaaatat cagcaggtag agagtttttt
    99241 tgcaactagc ttctgtatat gatgtttaca aagaatggta caagaaaaga tcatccttga
    99301 aaaaggaaag ctaacaataa ctagcatcat ataagagctt ttaaggatag aacagtagaa
    99361 taggaatcta tgagcaagtc ctctcgtata aataaaatag gagggaagta gcagcatatt
    99421 tttcataaag tggctctctt tcttcatttt tactttggtt gctcctattt gaaaattcga
    99481 gcacactcaa atacaataaa aagaaatggc aagggagagg attagatgaa aaaagaagaa
    99541 aaaatcgcga ttttacaaga gatcatccga attaaatcag tgaatggaaa cgaaggtgaa
    99601 gtagcagcct atttgaataa gcttttggca aagcatgaca taacaggaga gattgtttct
    99661 tacagagatg gtagagataa tttgattgct cgttaccaaa agggccaatc aggaaaagtg
    99721 ttaggcctat ctgggcatat ggatgtcgtg gcggctggtg atgaatcgtc ttggacctat
    99781 gcaccctttg cagcagaaat ccatgggaac cgtttgtacg gacgtggtgc tacagatatg
    99841 aagagtggct tggcagcaat ggtgattgcc atgatcgaac tgaaagagtc aggaaaacca
    99901 tttaacggaa cagtcaaatt attagccact gtcggagaag aagtgggtga actaggtggg
    99961 gaacagctca cgaaagcagg ctatgtagat gacttagatg ccttgatcat cggagagcca
   100021 accaattaca gtttgatgta tacgcacatg ggatcaatca actatacagt cacctcgcac
   100081 ggaaaagaag cgcatagctc tatgccagac caaggttata atgcaatcaa tcacctaaat
   100141 gaattcatta cgaaagcaaa tgctgaaatg aatcacctcg ctgaaacaat cgagaatcct
   100201 gtcctaggaa aaacaatcca taatgttaca ttgatcagtg gcgggaatca agtcaacagc
   100261 atcccaagcc atgcgcagct ccaagggaac attcgatcga ttccagaata cccaaatgat
   100321 aaaatcattg cattgctgca atcaatcgtc aatgaattga atcaagagac agactatcat
   100381 ttggaattga tgatcgatta caacaaaata cctgtcaaag ctgatccaga ttctcctttg
   100441 attcattgca ttcagcaaca attcagccag ccattacctt tagttggagc ggcagcaaca
   100501 acggatgcag ccgaatttac gaaagctaac cattccttcg actttgtcgt ctttgggcct
   100561 ggtgtcgtta ctttgcctca tcaagtagat gagtatgttg aaatcgataa ttatttggat
   100621 atgatcgaaa aatatcaagg aattatttta tcctacttag cgtaagattt ttttaataaa
   100681 tgaaaaaaca gagccagatt agcattattt
//
LOCUS       DAZKPE010000002        87462 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000002 DAZKPE010000000
VERSION     DAZKPE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.002"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..1083)
                     /locus_tag="ACG930_000102"
     CDS             complement(37..1083)
                     /locus_tag="ACG930_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFQ0517299.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(1094..1366)
                     /locus_tag="ACG930_000103"
     CDS             complement(1094..1366)
                     /locus_tag="ACG930_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFQ0517300.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(1401..2309)
                     /locus_tag="ACG930_000104"
     CDS             complement(1401..2309)
                     /locus_tag="ACG930_000104"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0517301.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(2441..3673)
                     /gene="pepT"
                     /locus_tag="ACG930_000105"
     CDS             complement(2441..3673)
                     /gene="pepT"
                     /locus_tag="ACG930_000105"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFQ0517302.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(3688..4809)
                     /locus_tag="ACG930_000106"
     CDS             complement(3688..4809)
                     /locus_tag="ACG930_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFQ0517303.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(4806..5507)
                     /locus_tag="ACG930_000107"
     CDS             complement(4806..5507)
                     /locus_tag="ACG930_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFQ0517304.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(5651..6091)
                     /locus_tag="ACG930_000108"
     CDS             complement(5651..6091)
                     /locus_tag="ACG930_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFQ0517305.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(6220..7146)
                     /gene="dnaI"
                     /locus_tag="ACG930_000109"
     CDS             complement(6220..7146)
                     /gene="dnaI"
                     /locus_tag="ACG930_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFQ0517306.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(7146..8519)
                     /locus_tag="ACG930_000110"
     CDS             complement(7146..8519)
                     /locus_tag="ACG930_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFQ0517307.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(8542..9033)
                     /gene="nrdR"
                     /locus_tag="ACG930_000111"
     CDS             complement(8542..9033)
                     /gene="nrdR"
                     /locus_tag="ACG930_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFQ0517308.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(9345..9677)
                     /locus_tag="ACG930_000112"
     CDS             complement(9345..9677)
                     /locus_tag="ACG930_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFQ0517309.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(9729..10358)
                     /gene="coaE"
                     /locus_tag="ACG930_000113"
     CDS             complement(9729..10358)
                     /gene="coaE"
                     /locus_tag="ACG930_000113"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFQ0517310.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            complement(10322..11158)
                     /gene="mutM"
                     /locus_tag="ACG930_000114"
     CDS             complement(10322..11158)
                     /gene="mutM"
                     /locus_tag="ACG930_000114"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFQ0517311.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(11203..13848)
                     /gene="polA"
                     /locus_tag="ACG930_000115"
     CDS             complement(11203..13848)
                     /gene="polA"
                     /locus_tag="ACG930_000115"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFQ0517312.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSADIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(13974..14657)
                     /locus_tag="ACG930_000116"
     CDS             complement(13974..14657)
                     /locus_tag="ACG930_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFQ0517313.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(14650..15135)
                     /locus_tag="ACG930_000117"
     CDS             complement(14650..15135)
                     /locus_tag="ACG930_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFQ0517314.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(15442..16776)
                     /gene="murC"
                     /locus_tag="ACG930_000118"
     CDS             complement(15442..16776)
                     /gene="murC"
                     /locus_tag="ACG930_000118"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFQ0517315.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(16907..17668)
                     /locus_tag="ACG930_000119"
     CDS             complement(16907..17668)
                     /locus_tag="ACG930_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFQ0517316.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(17684..18166)
                     /locus_tag="ACG930_000120"
     CDS             complement(17684..18166)
                     /locus_tag="ACG930_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFQ0517317.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(18186..20366)
                     /locus_tag="ACG930_000121"
     CDS             complement(18186..20366)
                     /locus_tag="ACG930_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFQ0517318.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(20510..21241)
                     /locus_tag="ACG930_000122"
     CDS             complement(20510..21241)
                     /locus_tag="ACG930_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0517319.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(21310..22251)
                     /locus_tag="ACG930_000123"
     CDS             complement(21310..22251)
                     /locus_tag="ACG930_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFQ0517320.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(22431..22799)
                     /locus_tag="ACG930_000124"
     CDS             complement(22431..22799)
                     /locus_tag="ACG930_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFQ0517321.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(23410..24801)
                     /locus_tag="ACG930_000125"
     CDS             complement(23410..24801)
                     /locus_tag="ACG930_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFQ0517322.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(25014..25400)
                     /locus_tag="ACG930_000126"
     CDS             complement(25014..25400)
                     /locus_tag="ACG930_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFQ0517323.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(25456..26079)
                     /locus_tag="ACG930_000127"
     CDS             complement(25456..26079)
                     /locus_tag="ACG930_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFQ0517324.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(26143..26811)
                     /locus_tag="ACG930_000128"
     CDS             complement(26143..26811)
                     /locus_tag="ACG930_000128"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFQ0517325.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(26823..27263)
                     /locus_tag="ACG930_000129"
     CDS             complement(26823..27263)
                     /locus_tag="ACG930_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517326.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(27322..27987)
                     /locus_tag="ACG930_000130"
     CDS             complement(27322..27987)
                     /locus_tag="ACG930_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517327.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQF
                     PQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAME
                     KAN"
     gene            complement(28172..28570)
                     /locus_tag="ACG930_000131"
     CDS             complement(28172..28570)
                     /locus_tag="ACG930_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFQ0517328.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(28567..29340)
                     /locus_tag="ACG930_000132"
     CDS             complement(28567..29340)
                     /locus_tag="ACG930_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFQ0517329.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(29337..30020)
                     /locus_tag="ACG930_000133"
     CDS             complement(29337..30020)
                     /locus_tag="ACG930_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFQ0517330.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(30187..31074)
                     /locus_tag="ACG930_000134"
     CDS             complement(30187..31074)
                     /locus_tag="ACG930_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517331.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(31071..31940)
                     /locus_tag="ACG930_000135"
     CDS             complement(31071..31940)
                     /locus_tag="ACG930_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517332.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(32077..33363)
                     /locus_tag="ACG930_000136"
     CDS             complement(32077..33363)
                     /locus_tag="ACG930_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0517333.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            33636..34214
                     /locus_tag="ACG930_000137"
     CDS             33636..34214
                     /locus_tag="ACG930_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0517334.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            34214..35143
                     /locus_tag="ACG930_000138"
     CDS             34214..35143
                     /locus_tag="ACG930_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517335.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            35140..36876
                     /locus_tag="ACG930_000139"
     CDS             35140..36876
                     /locus_tag="ACG930_000139"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0517336.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(36939..37775)
                     /gene="pheA"
                     /locus_tag="ACG930_000140"
     CDS             complement(36939..37775)
                     /gene="pheA"
                     /locus_tag="ACG930_000140"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFQ0517337.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(37772..38281)
                     /locus_tag="ACG930_000141"
     CDS             complement(37772..38281)
                     /locus_tag="ACG930_000141"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFQ0517338.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(38274..39569)
                     /gene="aroA"
                     /locus_tag="ACG930_000142"
     CDS             complement(38274..39569)
                     /gene="aroA"
                     /locus_tag="ACG930_000142"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFQ0517339.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(39582..40673)
                     /locus_tag="ACG930_000143"
     CDS             complement(39582..40673)
                     /locus_tag="ACG930_000143"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFQ0517340.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(40690..41856)
                     /gene="aroC"
                     /locus_tag="ACG930_000144"
     CDS             complement(40690..41856)
                     /gene="aroC"
                     /locus_tag="ACG930_000144"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFQ0517341.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(41858..42922)
                     /gene="aroB"
                     /locus_tag="ACG930_000145"
     CDS             complement(41858..42922)
                     /gene="aroB"
                     /locus_tag="ACG930_000145"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFQ0517342.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(42955..43977)
                     /gene="aroF"
                     /locus_tag="ACG930_000146"
     CDS             complement(42955..43977)
                     /gene="aroF"
                     /locus_tag="ACG930_000146"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFQ0517343.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(44636..45610)
                     /locus_tag="ACG930_000147"
     CDS             complement(44636..45610)
                     /locus_tag="ACG930_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFQ0517344.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(45591..47474)
                     /locus_tag="ACG930_000148"
     CDS             complement(45591..47474)
                     /locus_tag="ACG930_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFQ0517345.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(47492..49717)
                     /locus_tag="ACG930_000149"
     CDS             complement(47492..49717)
                     /locus_tag="ACG930_000149"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFQ0517346.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            49832..50866
                     /locus_tag="ACG930_000150"
     CDS             49832..50866
                     /locus_tag="ACG930_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0517347.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(50933..51946)
                     /locus_tag="ACG930_000151"
                     /pseudo
     CDS             complement(50933..51946)
                     /locus_tag="ACG930_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(52024..52212)
                     /locus_tag="ACG930_000152"
     CDS             complement(52024..52212)
                     /locus_tag="ACG930_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFQ0517348.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(52652..52780)
                     /locus_tag="ACG930_000153"
     CDS             complement(52652..52780)
                     /locus_tag="ACG930_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFQ0517349.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(52783..54156)
                     /gene="rlmD"
                     /locus_tag="ACG930_000154"
     CDS             complement(52783..54156)
                     /gene="rlmD"
                     /locus_tag="ACG930_000154"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFQ0517350.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(54267..55322)
                     /locus_tag="ACG930_000155"
     CDS             complement(54267..55322)
                     /locus_tag="ACG930_000155"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFQ0517351.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(55332..56762)
                     /gene="gatB"
                     /locus_tag="ACG930_000156"
     CDS             complement(55332..56762)
                     /gene="gatB"
                     /locus_tag="ACG930_000156"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFQ0517352.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(56759..58231)
                     /gene="gatA"
                     /locus_tag="ACG930_000157"
     CDS             complement(56759..58231)
                     /gene="gatA"
                     /locus_tag="ACG930_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFQ0517353.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(58231..58536)
                     /gene="gatC"
                     /locus_tag="ACG930_000158"
     CDS             complement(58231..58536)
                     /gene="gatC"
                     /locus_tag="ACG930_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFQ0517354.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(58642..60678)
                     /gene="ligA"
                     /locus_tag="ACG930_000159"
     CDS             complement(58642..60678)
                     /gene="ligA"
                     /locus_tag="ACG930_000159"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFQ0517355.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(60695..62929)
                     /gene="pcrA"
                     /locus_tag="ACG930_000160"
     CDS             complement(60695..62929)
                     /gene="pcrA"
                     /locus_tag="ACG930_000160"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFQ0517356.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            63084..64643
                     /locus_tag="ACG930_000161"
     CDS             63084..64643
                     /locus_tag="ACG930_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFQ0517357.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(64754..66685)
                     /locus_tag="ACG930_000162"
     CDS             complement(64754..66685)
                     /locus_tag="ACG930_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFQ0517358.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(66703..67617)
                     /gene="pfkB"
                     /locus_tag="ACG930_000163"
     CDS             complement(66703..67617)
                     /gene="pfkB"
                     /locus_tag="ACG930_000163"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFQ0517359.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(67614..68366)
                     /locus_tag="ACG930_000164"
     CDS             complement(67614..68366)
                     /locus_tag="ACG930_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0517360.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(68525..68734)
                     /locus_tag="ACG930_000165"
     CDS             complement(68525..68734)
                     /locus_tag="ACG930_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517361.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(68745..70073)
                     /locus_tag="ACG930_000166"
     CDS             complement(68745..70073)
                     /locus_tag="ACG930_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517362.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            70209..70364
                     /locus_tag="ACG930_000167"
     CDS             70209..70364
                     /locus_tag="ACG930_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFQ0517363.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(70438..71025)
                     /gene="yihA"
                     /locus_tag="ACG930_000168"
     CDS             complement(70438..71025)
                     /gene="yihA"
                     /locus_tag="ACG930_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFQ0517364.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(71108..72358)
                     /gene="clpX"
                     /locus_tag="ACG930_000169"
     CDS             complement(71108..72358)
                     /gene="clpX"
                     /locus_tag="ACG930_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFQ0517365.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(72605..73894)
                     /gene="tig"
                     /locus_tag="ACG930_000170"
     CDS             complement(72605..73894)
                     /gene="tig"
                     /locus_tag="ACG930_000170"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFQ0517366.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(74048..74980)
                     /locus_tag="ACG930_000171"
     CDS             complement(74048..74980)
                     /locus_tag="ACG930_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517367.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHQVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(75137..75796)
                     /locus_tag="ACG930_000172"
     CDS             complement(75137..75796)
                     /locus_tag="ACG930_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFQ0517368.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(75799..76824)
                     /gene="sppA"
                     /locus_tag="ACG930_000173"
     CDS             complement(75799..76824)
                     /gene="sppA"
                     /locus_tag="ACG930_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFQ0517369.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(76837..77127)
                     /locus_tag="ACG930_000174"
     CDS             complement(76837..77127)
                     /locus_tag="ACG930_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517370.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            77536..79341
                     /gene="glmS"
                     /locus_tag="ACG930_000175"
     CDS             77536..79341
                     /gene="glmS"
                     /locus_tag="ACG930_000175"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFQ0517371.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(79413..80768)
                     /gene="glmM"
                     /locus_tag="ACG930_000176"
     CDS             complement(79413..80768)
                     /gene="glmM"
                     /locus_tag="ACG930_000176"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFQ0517372.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(80792..81961)
                     /locus_tag="ACG930_000177"
     CDS             complement(80792..81961)
                     /locus_tag="ACG930_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFQ0517373.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(81958..82845)
                     /gene="cdaA"
                     /locus_tag="ACG930_000178"
     CDS             complement(81958..82845)
                     /gene="cdaA"
                     /locus_tag="ACG930_000178"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFQ0517374.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(83034..86726)
                     /gene="nifJ"
                     /locus_tag="ACG930_000179"
     CDS             complement(83034..86726)
                     /gene="nifJ"
                     /locus_tag="ACG930_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFQ0517375.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            86925..87446
                     /locus_tag="ACG930_000180"
     CDS             86925..87446
                     /locus_tag="ACG930_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFQ0517376.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT        24111 a        19017 c        15522 g        28812 t
ORIGIN      
        1 tttgatttga taaaaagggt agatcttata aaagacctac ccttgatttt ctttattctc
       61 tttttttact tctattattt cttctttgat cactcttcgc cgttcagcaa tcacatacac
      121 aaatccatag agaaatggca agataaagga actgaaacga tacagtaaaa gcgaagaaac
      181 tgcgtcaact gttccaacaa ctggtctgaa taataacaaa tagacaaatt caaaggaacc
      241 aataccagca ggcgtaggaa taacccctga aagcactact gcaaagctga taaacgaaat
      301 ggtcagtaga aaatctattt taggatggtt ttcaatcaga atcaaataag gaagtacata
      361 ccaaaataca agttttaaca tattccatag ataaatccgc aatagcgcag tcctgtcttg
      421 gataatggtt tggaccgttt cccttaaaga gtagatctgc tgattgcatg tatccaccca
      481 tttccgcaaa cgctcacttt taaataactt attcgataag ctgacaaaaa atatttgaac
      541 attcaagctg acggacatcg ccaataaaaa ggcaacaatc acgatcgtca aaaggatacc
      601 agcgatgata aaccagatca ttgatggacc attagaataa aaaagagaga attggatgac
      661 caagccagct aatgcataag tgatcactgc cagtttgtac ataatcatat ggagtgctgt
      721 cacccctgct ccctgggata gcttcattcc ttttttgtta taaaaataaa tctccgagat
      781 cagcgttcct gtaccaaacg aaacgattcg gtaaaacgca atatagctag aggtcaagaa
      841 cccatctttc gttgtaaaat tcggcgcgaa aggttcagca atttctttga ttgagcgccc
      901 ttcagcgatt tggtaaactg tccctaatat aacagccgct gccaaaacaa caacactggt
      961 agacagcaat tcggcaaaga tatctgcaaa tgattgattg attaaataat aaataatggc
     1021 aaaaatcaca atcagcaaaa gcagattcag aatgatttta gttttcgttc ctttagacga
     1081 catctcctgc tccttaatgg aaaaaataaa tgagaatcaa atcaacaagt acacctgcag
     1141 cgaatcctat agtaaacttc tttttccgag ttttatgatg gaaaactttt cgagagatca
     1201 atcctcccaa accaccgcct aacaggctga caaatatcaa attattctca ggaacacgcc
     1261 agccgctagt tctagcctga tgtttatcat accccatcag acaaaataag taaaaattca
     1321 caatgaaaag gtaaaaccac aaaggattgt gtaacaatac atccattact cttcttccaa
     1381 ctttctgtta actactattt ctaagctttt tcttctttct ttggtgaata aactgttaat
     1441 ccttttgata caacagataa ttcaactgga agatcatctg tcgtgtctcc atccgttcga
     1501 gtgcccacag atttttcctg cgcttggatt ttcatgcgtt tggctgtgaa ataagtaatg
     1561 ccggggatcg tatagaattt gcctctcatg attctaggca aataaaaaat aaatcggaaa
     1621 atatctaagg aaggtacgat cgttacatga aattttccat catctagggt cgctgagtcg
     1681 tcaaaatttg taaaaccgcc cacggagtta gacatcgtga ctgtcaacag ttgggatttt
     1741 cctttccaat gctcctcgtc tgtttctaaa tccaaatgat attttttctt cttcagcaat
     1801 aacttaaaaa acttcttgat aaagatccac gagccgtaac gctgtttttc ttcttgactg
     1861 atccaaactg ctgtatctgc taagattccg attgtcagtg tagagataat gacttcatca
     1921 ttgacttgac catagtctat tttccgtaca ttgccttcca ggatcacgtc agcagcttct
     1981 tcttttttga ggggaatctc aagaacacgt gcaaggttgt tgacagttcc acctggaagt
     2041 aatccgacat ggtattgaga taatgttttt tggaacgctt ggacgatatg atgaatcgtg
     2101 ccgtctccac ctataattac taaagtatca gcttctatgg cttctgcttt cttgactaat
     2161 tccgcatcat caatcgatgg gccagtttca gctagttcta catataattc tggctgcttt
     2221 tcttttacat aatcttgaaa ccagcgtgct aatttctcac cctcatcttt ccctgaactt
     2281 ttgttataaa aaactagcag cttttccatt ctttacctcc tatttactct tcaaaaaaga
     2341 gggcgggaca accaattcca ttgtcctgcc ctttagcctt agacagatga cattccatca
     2401 ttgggacgaa cgccttgtca taagctgttc tttttcgatt ttaactcttt gtgttcaatt
     2461 ctgcaatttt tacaatcacg tctgttgctt tttccattac ttgtaaagaa acaaattcga
     2521 atcgtccgtg catattttct cctccggcaa atagatttgg cgtcggaata cccatgtaag
     2581 agatttttga accatctgtt cctccacgaa ctggttcgat cactggagag ataccaagct
     2641 cgatcattgc ttgtttcgct aattccacga tgctcatatc tttttcaatg atttctttca
     2701 tgttgtaata ttgatcatac atatctactt tgattcgttc ttgatcaaat cgctgattca
     2761 actcttcttg gatatgtgtg atttgtgctt tgcgtgcttc gaatttttca cgatcatgat
     2821 cgcgaatgat ataactcata gaagcttctt caggattccc atccaatgcc atcaaatgga
     2881 agaaaccttc gtatccttcc gttttttctg gaacttcatc ggctggaagc tgattatgaa
     2941 aatcgattgc taactgtaga gcattgatca ttgtatcttt tgccgtccct ggatgtacat
     3001 ttttcccttg gatcgtaata tttgcttgag cagcactaaa cgtttcatac tgcaactcac
     3061 ctaaaggacc accatcgact gtataagcaa aatctacatc gaattgctca acatcgaatt
     3121 tatccgctcc gacaccgatt tcttcatcag gaccaaaagc cactttgatg gtaccgtgag
     3181 ggatagaagg attattgatc aagatctcca ttgcagtcat gatttccgca atccctgatt
     3241 tgtcatctgc tcccagtaat gtactgccat ctgttgtgat caatgtgtgg ccttcataat
     3301 ttttcaaatt tggaaaatct tttgtattca atgtatagcg ttcttccgca tctagtacga
     3361 tcgtagactc gccatcatag ttttcaatga tttgtggatt gactcctact gcattaaaat
     3421 ctgctgtatc catgtgggaa ataaatccaa tggaacgcac ttcatgatca acattgcttg
     3481 gtaatgttcc cataacgaat ccgttatctt cattatagaa aacatcagct aagcctaact
     3541 cttctaattc ttttttcaat tcttgcgcaa aagcaacttg tgtctgagtc gatggagtcg
     3601 ttttgcttgt tgcatcggag cgtgtttctg ttttgacata tcgtaaaaaa cgtggcaaaa
     3661 gattttcgta catagtattc tctcctttta attaaattga aatgggtttg tatttgtttc
     3721 agaaacgaaa aagttaatat cccaattttc ttcttgtttc caagattcaa atttctcgat
     3781 aaatcgttgc ttgcataacg attcaatata atgaccggga tcaattgcaa tcaacccagc
     3841 gctttgcata tcatgagccg tatgataata gatatctccc gtgatataga catctgctct
     3901 ttgggcgatt gcttgcggat aaaatttttc accgcttcca ccgcaaatcg caatgcgctt
     3961 cacagaggat tttgcatttt ttggctggac tattctcagt ccatctagtt ggaacgcttc
     4021 ttttacttgt tctacaaatg cctctataga aatttcttgc ggcaattcac ctactcgtcc
     4081 taacccaaac atttcgactg gttcatctat agcgaaaaga tcataagcag gttcctcata
     4141 aggatgagct gaccgcatgg cttgaatcac ttgtttttcg atagtttccg gcaaaataac
     4201 ctcaactttt gcctcttgaa cttgttctgt cttccctact ttcccaatcg ctggttgtgc
     4261 accagcttcc ggagtaaatc gaccgtgtcc aatcgaggta aaacttgtac cggtataatc
     4321 accttgtgta ccagcaccag ctgcagctaa tacttcacgc attttctgtg catgatccac
     4381 aggtacataa acggccagtt ttttataatg aatctcatga gtctttacta aataactctc
     4441 cacttcaata ccgagaagtt cacaaaacca gtcattcagt ccatcccaaa taatatccat
     4501 gttcgtgtgt gctgcataga cggcaatatc atgtttcaac aaatctgcat acattttttc
     4561 ttgtggctga tcagtaacca gccgttttac aggacgaaag attggaggat gtttagcaat
     4621 cagcaaatcg atttttttct tgattgcttc ttcgaccact tctggacgaa cgtctaatgt
     4681 catcattact cgttggattg gcttatccaa tgttccgata tgcagtccga ctgggtctcc
     4741 ttcttcagct agccactgag gacaatagct ttcaaacttt tggatgaaag tgcgtccgct
     4801 gattgtcatg gctttaaaac ctcctcaatc atttggattt cctgctcgat ttgtttttga
     4861 cgtgcctctt gattagctgc ttgtttgagc tgttcacgga tagcttttct ttgttgaagc
     4921 tctcttgtcc attttgattt gaagatctca cttttctctt caagcagaaa tggcccgaac
     4981 atcagctcca tttcattgta agtaactggt ttttgttctt tttcggctac aatgatttca
     5041 tatatttttt tattttcttc aagtattttt tctgattgga ttttatactg attttcttgc
     5101 agccaagatc gtaatgtacg ctctccgatg tttggctgaa ggatcaaacg ttcttgtccg
     5161 cttaagcgtt gattcaactt gccagcttct aggatatctc ggatcagtga acctcccata
     5221 cccgcaatcg tgacagctgt aataccatct tgtggctgga tagcatctag accatttgca
     5281 aggcgtacgg tgatacggtc ttctaatcca tcttttttga cttgcttacg tgctgattca
     5341 taaggacctt gaacgacttc accagcaact gcatattcga tttttcctct taatatcaat
     5401 gcaacgggta agtaagcgtg atctgatcca atgtctgcta aacgagcgga ttcagggaca
     5461 aagtcaccca ctgcggctaa gcgctgagat aaatctaaat ggttcatagc ttcactcctt
     5521 ctagataatt atagcatttt ccaaataaaa taaggagact aggaataaaa aaattcccat
     5581 atctccttaa aaaatatacc ttttcgttct ataaaacaac attttcttat ttttgaaaaa
     5641 atgttattgg ttatttgttc aatgaaacat caataatcga atctccagga acttgcggtg
     5701 ggatagacat cgtcatgatc ggcatctcaa ctaatgtaaa ttggactttg tcaccgattt
     5761 tcaattcatt tatgtccacg cttatttttt cagcagtagc atttaagatc actccgtcat
     5821 tgctgaatga cgttcccata ttcgctggat cttctttggc catgacatcg acgagtttca
     5881 actgaagcgt ttcttcttct gcttctactt gagtgatact ttcaatcgtt ccgacaaata
     5941 tgctttgtct ctccgttttc gtactgcttg tttttactgt ttgacccgca tcaatcgaat
     6001 caacagaacc tgtgttgcta tctgcgctac cgcagcctgc taaaagaaaa aatagaccaa
     6061 ctacagatat actagaaaaa atagccctca taaaaaatcc tccgtttaag tttctgcatt
     6121 acttgttgcg gtgattgtct ccggtcattt ctgtccatat aatgattcgc tgacctgctt
     6181 ttactactag gtcaaatgtc agttggactt gtcaactgtt caaccattgc gtcggttgcg
     6241 accagtcatt tcgatttctt ttgtcaaata acgtatgcgt tccattatcc gtttcgcttt
     6301 tagcggctct tcatctccac gttgagtgac ggacaaatgc tgttccaatt catccattgt
     6361 aaaattcgat gagaagaagg ttggtaactg ttcctgcatc cgatattgaa ggataacacc
     6421 gaatacttcg tctcgtatcc aactactcat cgcatctgca ccaatgtcat cgatcatcaa
     6481 aataggtgaa cgtttcactg catctaactt ttctgccact tgatcttttc cgattgcctg
     6541 tttcatctca acggcaaatg tcggaaaatg gactagcgtc gtggtgaatc cagcaatcgc
     6601 taattctctc gctgttgctc ctaataaata tgtttttcca ataccaaaac ttcctactag
     6661 atacagtcct ttatgatacc cttttggatc agcagtatat ttctctacaa aatctagggc
     6721 ttctaagctc gcatatcctc gtccatctgt acgttcaaag ttttcaaaag aagccgattg
     6781 aatatctttt ggcatatcca ttgcttttac tcggcttctg atttcttctt gtctttgccg
     6841 tgctaacaat gcttccgttg gtacataagt gacatccaca taatgaaaat tcaacgtcag
     6901 cttcggctca tagccgggag cgatcatcgt tggatcgttt ttttgatatt tacgcttttc
     6961 ttgcacgaat tcatacaatt tagcgtaact tttttcaata tccgcttgtg tcaattcttc
     7021 ttggtgtgcg cttagaaaag cttgaacatc cgcatcattt aagacttcag cgatcatttc
     7081 agcatacttt tcttgataat tgcgtttgct gatgatcctc ttcaattctt tgcctacgtc
     7141 ttccactaga tatcaccctc cttttttgcc aggtattctt taaaacggcg gtcaatctct
     7201 gcttttttct cgctgctgat ctgtttttca tcttttggct ggttgaccca atcaggaagc
     7261 ttttcccgtc gaacatttcg cttgccagtt tgataatttg tttgcttctt ttgttttgat
     7321 tgttttgctt gattacttat ttgccgaatg tgctggatcg cttcttctgc tgtggcgatt
     7381 ttcttttgtg cccattcatt tgccactgta tttacataac tggcatttaa gctagcatta
     7441 ttcttgatca ctagtacata attcagcaaa acattgatca cgctactgga aagacctgat
     7501 tgagaaacaa gatcttgcag taaccagttt tcttgtttag aaacatatcc gcctttttct
     7561 gacttgattg cttccagata tttcatcggt ggaatgctct gtgcttcttt tatcagctga
     7621 agcgctgcgt ttgtcaaatg ttcgtttgac gagggttcat tactgttttc agaaaccgca
     7681 actgtttctt ttgtttgctt caccggacgt ctctgcattg ccaaaatggc tttttgcagt
     7741 tctttttcag atactttttg ttcactaaag tcataagatt gactgatcag ttcgccaagt
     7801 gtcaattcat cgaaaccgta aagctgatga tacatgtcga cttgtttgat gattggatca
     7861 tcaagacttg caatatgttt ttttgccagc caatcattca aaaactgcca atcgaatgtc
     7921 gaatctgctt caagtaatgc tactgattca gattcttcaa aagatttatt cagcgattcg
     7981 atgttttctt gattagcagc gtacactgct tcattgaagc gataaacatc taaaaatttt
     8041 tttgtgattt tttgatatcc ctctgctgta tgccttttag gttcaaagaa ttgggtaagc
     8101 ttctggaatc gtcgttcacc aactttttcc agaagaagaa aagccagaac agagtctttg
     8161 aaaaatgctt taggaatgag tggttctaac agctcataaa taaaacgagg tcccagatca
     8221 ctatcttctt taaaataaac atccagtaag ccgattcctt ctagcttttt tcttgcatca
     8281 taaaattgcg ggataccgca gcctagacta ctaagcagat ctgcatgcat cccttcagga
     8341 cctttgccag attcttgaga gatttctgat aacagggtga aatagatact caaggcttct
     8401 ccgccgatta gtggctgata aagatacagc aaggcgttct tgctgtcttc tctcagcgga
     8461 gccgcttttc ttccttggta aatatttttt ggttgaagct ctttccaagc attttccaag
     8521 gaaatgcctc ctttttgttt cttaattgtt ttctttatta ttctctttat tattttcttt
     8581 tgctttatcc acgatatctt gcaactcttt taagaaaaca gacatatctt tgaactggcg
     8641 ataaacactt gcaaaacgaa tataagcgat ttcgtctaaa tcaactaaat cttccatcac
     8701 atattcacca attagattcg tcgatacttc gttttctccg agactgcgta cgcggttttc
     8761 gacatggttg acgatttgtt ccatttgttc catagctaca ggtctttttt ctgctgaacg
     8821 gatgagtcct cttaaaattt tatcgcgatt gaactcttcg cgttccccgt ttttcttgat
     8881 tactaataac ggagcagctt caattcgttc aaatgtagtg aatcggaacg aacaattctc
     8941 acattcgcga cggcgacgga tcgcacgtcc atcatctgct tgacggctgt cgattactcg
     9001 tgaattatta tgttgacatc tgggacatct cattttgtct cacctcttgc atcgcatttt
     9061 atataaagga tgtgtctttc tttacaacta gttgtattat aacacgaaac aaatcacaaa
     9121 cgcgactgtc ctacccaaaa aacacggata taagaacaat tttttctact ttcatgcgta
     9181 attgtgtccc ctgtccttac taaatttcaa ttttccaata ctgatcacct tgattactga
     9241 gaaataactt acacaaaagc tgatttagtc atctagcaca aaaaacttga agcagatgaa
     9301 caccttctca tctgcttcaa gtcacatctc gattttttac tattttataa cttctcttcg
     9361 attcctgtat agtgtttcat tcgctgttcc tcgatttttt gctcatcggg aatgtggtca
     9421 ctttctggga gcggtgtttt actacgatca ggtgtcggat tttttcgttc ttgagtcaaa
     9481 tcttgccgct tcgcttcttc ttctgcctgc tggtcttcta tttcatcgat tcttgcttgg
     9541 tactgctttt ctttttcttc tgctgtttct gattgcgtac gaccttcatc gattagattt
     9601 tctttattga gcatctcgcc gattttttct tttgcgttac ctacgacttt atccttttga
     9661 ttttttaatg atcccatcgc tatccctcac tttctatata ctcaggatag caaaattgac
     9721 acagatactc aaagaaagcg attagcaaaa agccaatttt cgatttgtcc cacaagtttt
     9781 tcttttgttc cattgttgtc gaacaaaata tccgcacgct gctttttttc ttcgattgga
     9841 agttgactac taattctctg ctgcgcttgt tctagcgtca gttgattacg tttcatcaaa
     9901 cgctgaagct gagtttctgg cgtagtataa acgacagcta ctgcatccat atagtggtca
     9961 taatgacctt cgtagagcaa tgggatatct acaattacta aaggatgatt ggaacttaga
    10021 gaggcgattt gatcttttat cgcttttcgg ataaacggat ctaatagctg atcaagtttt
    10081 tgccgttttt cctttgatgg aaaaacaatc atcccaagtt tccctcgatc tagttgccca
    10141 tcaggctgca atacctcttg gccaaacact gatacaattt tcctcagagc aagcgttcca
    10201 ggctcaacag tttctctggc aatcacatcg ccatcgatca aaggaaatcc atgagactga
    10261 aagactttgg ctgccgtact tttaccggta gctattccac ccgtcaaacc taaaacaaat
    10321 cctactttgc gatttttagc ctttgacaat tcggacaata gtgcgtcccc ctttgtgcca
    10381 cttttgtttt cacgatcggc gttccacaac gtatacatgg tttgccagtt tgctgataga
    10441 catgcagtgc tacttgaaat ccgcctgatt ctcctaatgc attcaaataa ctgcgaatcg
    10501 tggtacctcc ggcttctatt gcacgatcca aaacatcaat gatcgataga cgtaattgtt
    10561 ctacctcttt ggggcgcagt gtgttcgccg gttgttctgg atggatcttc gcttcccata
    10621 atgcttcatc tacataaata ttacctagac cagtcactag acgttggtct agcagcaatg
    10681 gcttgattgc tttgtgggac tttttcagtc catttgcgaa atctgctaat aagaagctat
    10741 ctggcaaagg ctcaggtccc aatttcatga ttcctcggta agttgcactt gctccttttt
    10801 cgacgattgt catacgacca aattttcgta catcgttgta gcgaagttgg cttccatcct
    10861 caaaaaagaa aagtacatgc gtatgtttat cgattggtgt attttctttc gtaaattgat
    10921 attttccttc cattcgcaag tgtgagatca gttcacaatg atcgagatga aaaattaaaa
    10981 acttccctct acgtccaatg gattggatgg tttcgccaac aagagaagcc tcaaagatgg
    11041 gtgtctctgg ttgctcgatg atcttgggcc acaagacctg aactttttga atcgtttttc
    11101 ctactactaa ccgttccaat cctttacgaa cggtttctac ttctggtaat tctggcattt
    11161 tttcttttca ccttcattat attgctctgt cttaaacaat gtttattttg cttcgtacca
    11221 cgtttttccc caactgctgt cagtgatcag tggtacatga agagaaacag cttgttccat
    11281 aacttccttc accaatttat ctaatgattc aagttctttt tccggtacct cgaagacaag
    11341 ttcatcatga acttgtaaca gcatcgtagc ttgaagacct gtttctttta atcgtttatc
    11401 caattcgatc atcgcgattt tcaaaatatc agcagcactt ccttggattg gtgtattgat
    11461 agctgttcgt tccgcaaaag aacggatatt gtaatttctt gaattgatgt ctggcagata
    11521 tcgacggcgg tgatacagcg tttcgacgta gccttggtct tttgcttcgc gtacgattct
    11581 ttccatatat tctttgacac ctgggtattt ttcaaagtac gtatcgatgt attgctgtgc
    11641 tgcttttcgg ctgattccta gattttgtga aagtccgtaa tcagagatgc catacacgat
    11701 accaaaattc actgcttttg cctgcctacg catatttggt gtgacatcct ctgccttttc
    11761 gattccaaat acacgcatcg ctgtgctggc atggatatct tgaccttcta ggaaggcagc
    11821 tttcaaatgt tcatcatttg agatatgcgc aagtacgcgt aactcgattt gtgaatagtc
    11881 agaagaataa atcagccagt ctttttctct aggaacaaat gcctgacgta tctttctccc
    11941 ttcatctaat cgaatcggga tgttctgcaa attaggatca acagagctta atcgtcctgt
    12001 ttgggtcaat gtctggacat aacgggtatg cacttttcca tctgattgga tcactttcag
    12061 cagtccctcg acataggtag attgaatttt tgcaatttga cgataggtga ggatatcctc
    12121 tacgattggt gcttgttcac gaagctgttc cagtacatct acggctgtgg aatatccagt
    12181 ttttgttttt ttgataacgg gtaatcccat tttttcaaat aagatcactc ctaattgctt
    12241 tggtgaattc aaattgaatt cttcgccggc ttcttcgtag attttttgtt cgatctctct
    12301 taagcgagca gagaactcgc ccttcatttc ttgtaagcga gtcgcatcta ctttgatccc
    12361 gcttatttcc atctctgcca aaatgataga caatggcagt tccattttcc ggaaaagatc
    12421 ttcttggttt ttttctgcca gttcttggct caattttggt gtcaacgcat tgattgcagc
    12481 tacttttcgc gctaaatgag caaaaaagag ttcctcttct tctggtaaac cttttttcgc
    12541 ccctttgccg tatacagctt catctgattg gatatcgttg tatccgtaat gagcagctat
    12601 tccttcgata tctgcgcttt tttcattcgt atcgagaagg tatgcaccta gcaagacatc
    12661 aaaatcgatt cctttcgttt ttccagtata gcggtttaaa gcaacataag ttcgtttcgc
    12721 atcatatact tttttcagcc gagtcggatc agtgatccaa gaatggaacg ctcggttttc
    12781 gaatacagat agatcgttcg tgacataaat tttcttttct gtcccccacg ctactccgac
    12841 gatttcctct gtatgataat tgtcgcccat catttccacg tacaacgcca tatccgtagt
    12901 aaacatttcc tctttgaatt catgaacgac ttcaaacaaa atatcatcca tttttacttc
    12961 ttcttctacg atattcaatt tagaaaggaa ctgattgaaa tccatttctt tataaaacgg
    13021 aacgagttta tcgagatttt tcccttcata cttcaatgag tcgatagaga catccacagg
    13081 cgctgaagta ttgatggtcg ccaatttttt cgataagaaa gcctgctctt tgtcatttat
    13141 cagattttct ttcattttgc tttgcttcat ttcatcgata tgttcataaa ttccttcgac
    13201 tgagccatat tgtttcaata gcttgatagc tgttttttca ccgattttag tcacaccggg
    13261 gatattgtca gaggcatctc cggctagtcc cttcatgtca ataatctgtt ttggcgtcaa
    13321 cccatcatat ttttccgcta catgttctgg tgtatagctt tcgatatcgc tgacaccttt
    13381 tacagtgata tccactttta cttctttact agctaattga gtcaaatccc gatcacctga
    13441 aagcacgacg acatcaaatt gatctttgtc tactttttct gccaaagtac cgataatatc
    13501 atctgcttca taattgggca attcgtaata ctgtacccct agtcctgtca acaaatcacg
    13561 tatatatggc atttgttctt tgaattcgcc aggtgttttg gatcttccac ctttgtactc
    13621 cgcatacatt tctgtccgaa aagtcgtttt tcctgcatcg aacgcaacca gaacatgagt
    13681 cggttgctct ttttgcataa cattttcaaa catcgtattg aatgcataga ttgcatttgt
    13741 atgaagaccg tttctatttt tgaaacgttc aagagaattg tgaagcgcaa agaatgcgcg
    13801 aaaagccaca ctgttcccat caacgagtaa taatttattt tttgtcatct tcttaactcc
    13861 ttactgtaaa gttcttattc attctaacaa agaatcctgc ggaatgcgaa aagaaaaagc
    13921 gggaccatac caaataattc ggtatagccc caactgatga atttttttct tttttagttg
    13981 ttccgtccaa agattctcag aaacgccaag aacaagttga taaagtccaa atacagcttc
    14041 aatgccatga atacagcaat tccactatgt gctgttccgt ttgtctggac atagatatta
    14101 cggatgcttt ggttatcata agctgtaatc cctgcaaaga tgacgactaa cagtagggag
    14161 atgaacagct caactacgct acttctcaaa atgaagatgt tcaagactag tgcaatgatc
    14221 actccgatta aagctgcctg tcctgctctt ccaaccccgc taagatctct ttttgttgtt
    14281 actccgacaa cagacatccc catgaacatc aaagtagctg tcaagaaagc ttgcgttact
    14341 gttccaatat cgtagtatgc aagagtaacc gctaatgtta tgccattcaa aagagagtag
    14401 gcaataaatc caccgattgc taagctcgga ttcttttgtg cttttacgcc tagaaccatt
    14461 actaaaatca gttcaacgat ccacagaccc acaaagccta gtggaaaatt attgataaaa
    14521 gttgctaatt gcaaaggaaa tacccaaaga gccaagtaag aagtgactgc actaagggca
    14581 agtcccatac ctaaaaatcc ataaactttt gcataaaaac gattgatacc tgacattgat
    14641 gtacttggat tattcattca attcaccttc actttcgatt gctatttcca attcaggaac
    14701 ttgtggcggt tggaccataa cgacagcatc caacacacga tcttcgttcg tattctccgc
    14761 ttctacagaa atcgtcacca catccttcat cttatctact tttatgacct caaactgaaa
    14821 agtcagtgtt tcataatgga aaaccggttc aataaaattg acagaaaaat tgacaacatg
    14881 tgatcctggt ccaggaagat gctttgaaat tgcacttgtg atgatcccca tcagcatcac
    14941 tgatggaacg attggctgtt gatattctgt tttttgtgca aagtcatgtt ggatatacaa
    15001 aggatttgca tcattcgtca atcccaaata cagcaaaagc tggttatctt caatagattc
    15061 tgttaaggat aacgagtcgc cttcctcgat ttcatttatt gtttttccta gttttctcgg
    15121 cttacctatg ttcaagatag aaaccctcca gtttattttt aatcatacat tattgtacca
    15181 aaagtagcgt aaaaggcaag ttctgctccc ttgatttaac agattcctat agtttacaga
    15241 ggtcgtgaaa aagctgtcct gcatcaaata ataagaacag ccaagaaaaa acagcttctc
    15301 atgtttttga tttgattggg cttattaccg cagatgcaag cttttgaaca ccgtttatca
    15361 taagttgcaa aaaagggggc ttggcaagat ttttgccact ccccctcttt ctatttttat
    15421 aaggacactg cagtaattgt attacagtac atttttcgtc gtgctgctta aaagtttttc
    15481 atacgcttgt tcaaattttt gaacatctcc agcacccatg aagattacta ctgcatcatg
    15541 ataatctaac aatggagata cattattttc tttgatgact tctccacctt ttttgatttt
    15601 cgctccaagg tcttcaatct taacgtttcc ttgttcttcc cgagccgaac caaaaatatc
    15661 gcataagtaa actttatcag ctaaatcaag tgcttctgca aattcatcca tcaatgcaat
    15721 cgtacgcgta aacgtatggg gttggaaaac tgcaattatt tctttatctg gatatttttg
    15781 gcgtgcgcca tcaatcgttg ctttgatctc tgcagggtga tgcgcataat catcgactac
    15841 ggtcatgtct gctacgatct tttcactgaa tcgacgtttt actcctggga aagtcagcat
    15901 ttcttctgca acttctttca gatccagttt ttcgaaataa gctactgcaa taacacctaa
    15961 agcatttaag atattgtgtt taccgaatgc tggtacagtg aagtgcccaa caaattcatc
    16021 cccatgatag acatcaaaag cagaaccaga agttgtgcgt tcgatgtttc gtgcttggat
    16081 atcatcgttt tctgtgacac cataataata aatcggcaca tttgctttta atttgcgtaa
    16141 ataagcatcg tcaccatacg caaaaatagc ttttttcact tgtccagcca ttgtttggaa
    16201 agctgtaaat acatcgtcga tacttgtata ataatccgga tgatcaaaat cgatattggt
    16261 catgattgca tagtctggtg aataggcaag gaaatgacgg cgatattcac aggcctcaaa
    16321 tgaaaagaat tccgcttgcg gatcaccatg tcctgttcca tctccaatta gataacttgt
    16381 tggacggaca ccactcaata catgagagag cagtccagtc gtacttgttt ttccgtgaga
    16441 gcctgttaca gcgatactcg tataattttg gataaaatga ccaataaagt cgtgatagcg
    16501 aatcacttcc aaacctaatt cttttgctcg ctggatttct tcatgtgaat caggaaatgc
    16561 atttcctgca atgatcgtca tccctggttt tacattatct gcgttaaatg gcagaatcgt
    16621 gatatttgct ttttctaaat ctctttgtgt aaagaaatat ttttcaatgt ctgatccttg
    16681 gacatttaga ccttgttcat gtaaaacaag agccaaggag ctcattcctg aacctttgat
    16741 accaacaaaa tgatacaatt tattttgatt ttccatttga atcctcttct cttatctagc
    16801 gtccattctt ttagctatta cattcaacac gctcctcatt atcttataaa cgattgaaaa
    16861 tttcaaccaa atttatttgg aaaggaggat tcgcttgcta aaatggtcaa gtacgagaaa
    16921 aatccgtttt tattgactct ttaattctgg tgtaagaaga ccaaacttcc tctgatatat
    16981 caatgtgagg aataaaatct tttcctttcg gaccatagcc gttctcatcg tcatggagac
    17041 gttccatttc tcctaatact agcgcatgga aatattcctt aggccattga tgattcagtt
    17101 cttttgctgt aaagatgatc tcttcagaaa agtgaaggat ttccggcaca aatggcacag
    17161 cattcgcgaa aatagtttgt tcattttgcc atactttctc aaaagttgct cgagtcctgc
    17221 gttgcagtgt cggatcattc atcaataaga ttttttctgg tacagctcct aaggaatgaa
    17281 gaatctccag tgaaaaagtg gcgttctctc cagaatttgt agacttcgat tctatcagaa
    17341 aagccttatc gggcaaatca tagacttctt ttagatactg acgacagatt tcactttcac
    17401 tcatgccatc ttcaaaatga aatccttgct tttcaaaatt ctcataaagg attctagtcg
    17461 catgccccac ccctccgacc aaaaacaatt gatctacttg gccatttaaa tacatttgtg
    17521 ctgctttatc agctaagata ggaagacagt ttccagctaa aataagtgta ggtgccgtca
    17581 gttcctcaaa atttccctct tcaggtgcgg ctaaaaaatt taatagctga ttccagtctt
    17641 ttagattcct ctgctcactt ttttccaaag gccttctatc ctttcatctg attttttgtg
    17701 cttcattaaa gtcttctctt tttgtctcaa tccatttgat ttctccatga catcttccac
    17761 aacgatattt gcgtacatcg attcttctct tgcggcagat cgtggcagaa caatcttggc
    17821 atcgataata ctccatcttt atctgtttct tcgtcaaggc tggtgcatag cgcaaccctc
    17881 ctgttttttt caaaagatac ttgaaatcca tatctttatg ctgataccct cttccagcta
    17941 gatgaagatg ataatggcaa agttcatgtt tgatgattcc tgcaatcgtc tcttcgtctg
    18001 actcttcaaa tagcttcgca ttaaaatcta aatgatgatc gtttaaatga tagcgcccgc
    18061 cagttgtacg taagcgtgga ttgaacattg cttggtgctt gaaaggaagc tggaagcttt
    18121 ttaatgatat ctcttctact aactgctgca gttcttcttg tgtcaatttt tgttactcct
    18181 cattgttact cttcataagg ggaaagcatc gtcaaactga ttctgccttt tttcgtatcg
    18241 acttgttcta tccaaactgt tacgatatct cctactgaca cgacatctgt aggatgcttg
    18301 acgaattttt tgctgagttt cgatatatgg acaagtccgt cttgcttcac accgatatca
    18361 acaaatgcgc cgaagtcaat gacattacgg accgttccag tcaattccat ccctggtttc
    18421 aagtcttcca tactcaatac atctgtacgt aataagggcg ctggcatctc atcacgcata
    18481 tctcgtccag gttgtgtcag cccagctaaa atatcggcta acgtttcttc tccgactgat
    18541 aggctttcag ccagtttctc tacggataat cgtgtcaatt tttctactgc ttcttctgta
    18601 ccaagctctt tttctgaaag ttggactgaa gttaatattt cttttgcaat agaataactt
    18661 tcgggatgga tacctgtgtt gtccaaaatg tttttcccac cagggactcg caagaatccg
    18721 attgcttgtt catatgcttt tggtcctaag cgtggcactt ttttcaattg agttcgtgcg
    18781 gtgaattctc cgttttcttc acgataaatg acaatgtttt gggcagttgt tttattcaat
    18841 cctgatatat gctgcaagag ctgcgggctt gctgtattca catccacacc tacttggtta
    18901 accgctgttt ccacaacaaa atccaattgt tcagccaaac gtttttgaga aacgtcatgt
    18961 tggtactggc ctactccgac agctttagga tcgattttga ctaattcagc taaaggatct
    19021 tgcaggcgac gggcaataga aacagcactt ctttcttcaa cttgtagatg cggaaattct
    19081 tttcgtgcaa tttcgctagc ggagtaaaca gaagcgcctg cttcgttgac gatagcgtaa
    19141 taggttttat ggtcggcgga tttcaactgc tcagccacaa aaagttcaga ttcccgactg
    19201 gctgtaccat ttccgatagc taccatatct acttgatatt tattaattaa ttggataaaa
    19261 gctggtccag cagcttctct ttttgcttgc gctgcaggtt tatgaggata aataacttcg
    19321 attgctaaaa ctttccctgt cgcatctacg actgctagtt tacatccagt acgataagcc
    19381 ggatcaaatc ccaggacaac tttacctttt agtggcggtt gcaacaaaag attacggagg
    19441 ttttcgccga aaatagcgat tgcttgctca tctgcctttt cagtcaattc attgcgcagt
    19501 tctcgctcga ttgctggctg aataaagcgt ttataactat cctgataggc ttctctgacg
    19561 aatgaagaag aaggagaggc aggatttttg actatttggc gatccaagta agctaaaatt
    19621 gctgcttcat ctacttgaaa gaatactttc agaatatctt ctttttctcc acgattagta
    19681 gctaatattc gatgagaaac cattttatgg acgggttctg caaagtcata atacatttca
    19741 tatacgcctt tttcatctgc ttgctcatcc ttgacattgc tgacatacat acctttgtta
    19801 tacgtataag accgaatcca agtccgaaat tttgcattat cgctgacttg ttcagcaata
    19861 atctcatgag caccgtgcaa cgcttcttcg gcagaagaga cttctttttc tttgtcaata
    19921 tatttttctg cttcagattg cacctctcca tctgtaagct gcatcagcca cttcgcgagt
    19981 ggttcaagtc ctttttcttt agcaatcgtt gcttttgtcc gtcgtttttg tttgtatgga
    20041 cgatacaaat cttccacttg ttgcattttc acggcttggg tgatttctgc ttctaactcg
    20101 ggagtcagtt tcccttgttc atcgattagc cgaatcactt cagttttacg tttttctaag
    20161 ttttcaagat aggcataccg ctcttcgatt tcacgaatct ggacttcatc aagacttcca
    20221 gtcatttctt ttcggtaacg cgcgataaaa ggaacagtgt ttccttcatt taacaaatta
    20281 agtacagtag tcaactgctt aggacgatag tctgaaagtt ctttttgtac aagctgaatg
    20341 atcgtctggt tcaaattttc cgtcattaaa atgcctcttt tctgctaaaa attgcttctt
    20401 tattctatca tactttttat cctgggttaa actactgaaa gaaacaatat tctctataaa
    20461 aataaaaaga gccgcaacaa agtcacagct ccttcattct ttccattagt cagattccat
    20521 gccaaggtcc ttcgttgttc tgatattcaa tatcttgaag aataccttcc ttgtcaaaaa
    20581 caaccccatg caatgaccct ccgaatacag ccccaccgtc cattccgatt ttatgatcct
    20641 gaatccagag gtctgttgtc tgcatatctc catggagcat tggtgtaatc gtatgtccaa
    20701 atacaattgt cttacctgta ttgtttttcc cttcatgaaa tggttccctt atccaaataa
    20761 agtctcttag acttgtctta cgccagtctt tctttgtcaa atccacaccg gcatggacaa
    20821 aaagataatt ttcccattca taatacaagg ggcgctggac taaaaattta atcagttctg
    20881 aatatctcga ttggatcatc atcgagattt cagttgggga gtattcctcc gatgcccctg
    20941 ggtgaatcag gctttcaaac gtttcttttc caccatttct catataaggc gcataccagt
    21001 cctccggtga ttgcagaaat tgcaaaaaat attcttcatg gtttccccgg aggtaaatgg
    21061 ctcctgtttc ttcgactaat tgctttccta ataaaaaaca ttcttttgta cgaggacctc
    21121 gatcattgag atcccctaat aaaacaagct gatggatctt tggatcataa tagtgaataa
    21181 gtttttcaaa aagctcatgt ttgccatgga catccccaat agcataaatc aatgatttca
    21241 tgtggatcac catcctcaac gctagtatag cgcatattgg aaatggtcga caatcaaaac
    21301 tattgttttc tatttaatta aagctgtaaa ccgcagttct gcttcttctg gagagattcc
    21361 atggtcttga acatagcgat tgcgcggatg tttcgcacac tctatgctac atgctcctaa
    21421 atgtttttct tcattttcaa tggaagcaag aatctgacga ttgcactcag gattgctaca
    21481 attgatatat cgttcacatg gtgttccgtc aaaccagtcg cgaccgacga tttgtttatc
    21541 tacttggttg atatcgacag cgatccgttc atcaaacaca tacatcttgc cgtcccataa
    21601 ttctccttgg acttcaggat ccttaccata agtagcaata ccgccatgca gctgtccgac
    21661 atctttgaat ccttcacgga caagccaacc agaaaacttc tcgcaacgaa tgccaccagt
    21721 acagtaggtc actacccgtt tttccataaa ttcttctttg tgctcgcgga tccagtctgg
    21781 aagctctcga aaactgcgta tatctgggcg tacagcccct cgaaaatgtc ccaagtcata
    21841 ttcataatca ttccgtgcat caatcaccac tgtctgttca tctaaaatag cttctttaaa
    21901 ttcttgcggt gaaagatagg cacctgtcac ttggtttgga tcaatgtcct cttctagctt
    21961 taaacttaca agctctggac ggtatcttac aaacatcttc ttaaaggcat gtccttcgct
    22021 tggatcgatc ttgaacatcg tatcagcaaa tcgaggatca gctttcattg ctttcatata
    22081 ggcagtcgtg ttttcaacgg ttccagacac agtaccattt attccttctt cagctactag
    22141 aatacgacct ttaagatcca aagatttgca aaaggctaaa tgatttttgg caaattcctc
    22201 tggttcttcg atttttgtat aattgtaata aagcagtact tgataatcca tgtatttctt
    22261 ccttccttct tttcgttcct aaacagtata aagaaggcgt tcgcatttga cgatttattt
    22321 gcttgtgtat aattacgcat ggaaagtttt ttgtttacat aatattatta tttgaattaa
    22381 aaagacttcg ctttcctgtt tcgcacagaa aaacaaagtc tttatttcta ttatttacct
    22441 gtaaccgcaa agtagttgcc atcgggatca gcaaagttaa agacatattc ttctccaagc
    22501 tgtaccatat cacctaatgt gactgattgc gtctgcattt ttttatatag tccaaagata
    22561 tctttactgt aaaacatcaa agatggggca ctagtagctg tgccaggtga atgggactca
    22621 acaaatgctc gatcatataa cagaaatgag gtttgactgt cctcaactcc tacttcaatt
    22681 ataagcgtcc catccatttc ttgacgatct ttttccgcaa agccaactgc tctccaaaac
    22741 gttgcatttt tttctacatc gtccacataa agcatgattt ttatttcatt cgtaaacatc
    22801 tgtttcctcc taaacgatct gttctaacat tctcaacttt gtcagtttac cataggaaaa
    22861 tgggaaaatc tacgaaagct ctcaacagaa tcgtcctact taaatacgct tttctttaat
    22921 aataaataag ttggttgttt ttgttatttg cgctttcact tttcggaata aataatgtgt
    22981 atttatatgg aataaataaa aaaagaggtc gtgactaaaa acaagtcaca acctctggta
    23041 aacggtgttc tcctgacaac tcctcggtca caagacacaa tattcaacaa acatgagaag
    23101 ctattttttg aaattgctct ttgtgactca gagtgaaacg gcaggctcac gacctctttc
    23161 ttaaacggtg ttcaaaagct tgcatctgcg gtaataagct caaccaaacg taaaatatga
    23221 ggaactattt ttgtttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
    23281 ttattcacgg tgtttcagaa gtagcttctc ggaaataagc cgaaatttca caaaaatttg
    23341 agaaactatt tttaggaaac ttcttcttat ttcttaaagc tgaccacttc tatcacaacc
    23401 tctttttgac tatgcattca catcgatcac tttagaatca tcattgatga catcgcgatc
    23461 taaatctttg atgcgtgcac ttgtcacgat accagctacc atgctaccgc tgacgtttac
    23521 tgctgtacgt gccatatcga ttaatggttc aacagagata actaacccaa cgattgctac
    23581 tggcaagttc attgccccta aaacgatcag tgaagcaaat gttgcgcccc caccgactcc
    23641 agctacacca aaagaactga ttgttacaat tgccacaagc atcaaaataa attccaaact
    23701 aaagacattc actccagctg ctggtgcgac gatcgttgcc aacatagctg gataaacgcc
    23761 agcacagccg ttttgtccaa tagacaaacc aaaacttgct gagaaattag ctgttgcatc
    23821 atctactcct aaagcttttg tctgagtctc gatattcaat ggcaaagctc cagcacttga
    23881 acgtgaagta aacgcaaagc tcaataccgg aaaggctttt ttgaaatagt tgattggatt
    23941 gacttttgca ccaatcaaaa tcagtgagtg gacaatcaaa acagcaagca atgctacgta
    24001 agaagcaacg acaaatttac ctaaattgac gatagctgca aaatcacttg ttgccaaaac
    24061 gtttgtcatc aaagcaaata ctccataagg tgtcaaacgc aaaacaagcg tcacgatccg
    24121 cataatgatt ttatacagac tgtcgactaa atctgaaaag aatgctgctt cttttggcgc
    24181 ttttcttttc acgcctagat aagcgattcc gacaaatgcc gcgaaaataa cgactccaat
    24241 cgtacttgtt gcacgactac ctgctaaatc agcaaaaacg tttttaggga taaaggataa
    24301 aatctgctgt ggaatcgata agttttcaac tgtttcctga cgtgttgcca gttcagagat
    24361 tcgtgctgtt tctgcagctc cttgtgtgaa tttagctcct tggagtccga acagcattgt
    24421 tgaaccaatt ccgatcaatg ctgcaatagc tgttgttcca agtaaagaag tcaatacagt
    24481 cgcactaatt ttccctagct tttcagaaac tttcattttt gtgaatgcac caatgatcga
    24541 aataaacact aaaggcataa ctagcatttg caagaatgat acatatcctt gacctacaat
    24601 cccgatccat tccattgatt gagtaacgac tttgtcgtct acaccaaaga tcaattgaag
    24661 cagaccgcca aagacgatac caactcctaa tgctgtaaag acgcgtgttg aaaattttgt
    24721 atggcgcttt tgcatacgat agaacacata taataatgcc gcaaaaacta gaaccactaa
    24781 aactgtgatg agtgttgtca tttttctcct cctcatatta ttaatgacaa gtccatcgaa
    24841 ggaagtaaag gttcccgaga atgattcttc aaccatcctc ctgaaaaaat ttttttcagt
    24901 gacttttata ttttagacga tttttatcga aatgacattc tttttgctta caattagtaa
    24961 taaaaaaaca tacctgtgat agctttaatc tatcgcaggt atgtttttac tgtctattct
    25021 tgtttttctg attgaaaatt caattttacc ccaggctgat ctaaggcgat ctctgtcacc
    25081 tcataagaca ttcggcgtac gatatcgaat aacggtgcta ctagctcgtc cacttcttct
    25141 tgtgtgacat cattttgacc ttcaattttc cgattgagga tatgattgat ctgactcaca
    25201 cttccagata aaacatatgt atcaaacact aaacggaact ctaagcgtgc tcctacgatg
    25261 ctatgttctt tcggatagtt ttcgatcgtt tcttttaaag gcgagaagcc tactttcaaa
    25321 tctgtttcta cttcttggtt cggcaatctc atatcataat gaaatgcttc tacaacttct
    25381 ttttgtcttc tgatttccat ataattttat cactccttta tgaaaattat aacatatctc
    25441 ctttgaaagg ggatactact ttttaatgat gctctgcaag gtaaggattt cattcagatt
    25501 tcctaccaca taatctgccg ggatctcacc cagaaaatga tcgatgtcgt aaagacaagt
    25561 agcgactcct gcatttttcc ctgcttcgat atctaaacga cgatcgccga tcatcatcgt
    25621 gtctgttctt tctaaatgaa aagtatcgat caaataattt aaagatgctg gatcaggttt
    25681 acgaggaaag tcctgatcga tccctactac ttcctcaatc agatgtgcca atcgatgttc
    25741 ttttaacagg ccccatgttg attctgtcaa acggtgggtc aggatgaaat gacgaccgcc
    25801 gttgtctttt agcatttcca gtacttgttt cgtttctgga aatggacggg aaacttccgt
    25861 actttctttt tcatatcggt gaaataattc attaaactct ctggcattca agtttgattc
    25921 attgatcaaa taactagtag aatacttttt cattttgaag tagatttctt ttttgtccat
    25981 actgatacca aaatctttta gtgcttgcca tgcaccatct accattgcgg gatacgtatc
    26041 aaacaatgta ccatcaaagt cccatatata atttttcatg ttccttttgt tccattcctt
    26101 tgcttctttt ttctatctct cacttttaga taaaggtgtt ctttaaagta tttttttgtc
    26161 cagaattgtc aaatcatctg ctaatgtata ctggattggt tgtgcatttg ggatatcgat
    26221 cgtatccatt tgatcttcag gaacatcttc taaatatttt gtcagtgctc ggatgctatt
    26281 accatgaccc acaactagta aatcttgccg atcttttagt tttggtgcta gatgatcttg
    26341 ccataaggga atgatccgat tcactgtcat ttccagactt tctccgtatg ggatcaaatg
    26401 cggatccaag tgatcatatc tgcggtcaaa tctattttct gcggttaacg gcggaacttc
    26461 cgtatatcct ctgcgccatg tttttacttg atcttttccg tatatttctt tcatcttatc
    26521 tttgttttta cccacaagat ccccataatg ccgttcattt agacgccatg tttttattat
    26581 aggaagccat aactgaccca tttcttctag tgcgacttgt ccggtaagaa tcgcacgttt
    26641 caaaacagag gtataaacgg catcgaattg aagtccggct tcaagcattt tttgaccggc
    26701 aactgctgct tgttcttttc ctttttctgt taaggcgaca tctagccatc ctgtccagta
    26761 attttcaaaa tttgcttcgc tttcgccatg acgtaataat actaatttca ttcttttctc
    26821 ccttaaacat tcgtttcgaa ttttatacca catgttttgc atgtcacacg tattcgtcct
    26881 tttcctttag gtgcacgctg cttttgatga caattcgggc actcaaaaaa agtataactt
    26941 tttcgatcca ttttgacttg ctttttgttt tttatctgat gatatttttc tttgactcta
    27001 tcaagatatt tcaaataacg ttgattctca tttagtctgg ggtagatttt ttttgatagg
    27061 aaacgaaata tcatccatcc gaaaaagacg atgaacaaca attgtccgat tctatagggc
    27121 aaccaacgac ttagcaaact aaagacaagc gcagcgatca atagaccgcg attcaactga
    27181 tcaaatttcg catatcttcc ctgcataagt ttgtgatagt tctgctgaaa tcgtattagc
    27241 ctttctaacc atgtttgcat catattatct cctccatcat ctaatattta ttatgacaaa
    27301 aaaatccaaa aagaaaaagc cttaattggc cttttccatt gcaacttggt gaaggacatt
    27361 ccgatttctg gtaaagtcaa tcacaatcac tttcttttta tcttctctgt tgactactcg
    27421 aaatgtgtcc gtcaatggaa gaaacagctt cttagatggt agctgttgca tacgtataaa
    27481 acgatggatc atcgtaatca attgaggaaa ttgaatagac gtgtgaagca gacctggata
    27541 ttttttcaac agctgtgtcg ttttgatcag attccgtttt ttactgatca cttttaaaaa
    27601 gctttttaga atctgacgtc taaaaataga aaaagaattt tcgtcatcta tttgataacg
    27661 catttgtttt tgcagttctg ctgcagtcag atggatcttc ccatcgtttg tatcgatcat
    27721 taaaccttct ggaaacagtt caaccactgc tcgatcccaa gattcaagag aaagctcgat
    27781 ataatctttt actggtaatt ccaattctac cttaaaaaag tgcaaaacag ccgacagccc
    27841 ttctgcttga tagatttctc ctaatgttag cccctctaga tggaactctg gtgaaaaatg
    27901 cagcaatgtt ttattttcct gcaattgaac atatagaaat gtagatcgct caatcagagt
    27961 atcttttaaa acaactaaaa aattcatttt tctccccctt ttttcatcat ttttaaaata
    28021 gcatattttg aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc
    28081 ataagtattc acgagaaaaa tacaaacaaa aaagcggaaa taacgctcat ccgccttctt
    28141 gtttgtgttt atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat
    28201 tttcatctaa aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac
    28261 caatgacttt gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga
    28321 tgccttgacc aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca
    28381 caatatcttt ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag
    28441 aacctcttcc atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa
    28501 catcttcgcc cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa
    28561 gatctttcat ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc
    28621 atcttttcgt ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat
    28681 cattgcaacc acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat
    28741 tgccacgctc attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt
    28801 atcaaaagcc attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc
    28861 gtatcctggg atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa
    28921 tcctactgct gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct
    28981 cccctcgctc aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc
    29041 tactaagaac cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc
    29101 aatagcactg cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa
    29161 aaggatcaac ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt
    29221 gcgcatacga aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc
    29281 caaaatgact tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat
    29341 tggaagatca cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc
    29401 attccaaaac tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca
    29461 agggccaaga taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca
    29521 atcggcataa attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata
    29581 gccatcaatt gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat
    29641 actccagtgc cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat
    29701 atatcatata cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc
    29761 ccgatagcaa atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc
    29821 cctactagat ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt
    29881 ccgatcatca tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt
    29941 gcaaaaacaa acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact
    30001 tctttaaaat tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga
    30061 aagagttttc gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac
    30121 acacgtccca aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt
    30181 gtttttttat tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa
    30241 tacgatggca gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg
    30301 tgtataggaa gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg
    30361 caaagctact aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc
    30421 cgcggcatag gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt
    30481 tagaccgtct aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg
    30541 aaagaagaag atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt
    30601 gattcccaaa accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc
    30661 cgcaaaagga accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact
    30721 ttgataaatc tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt
    30781 caccaaagcg atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa
    30841 caaattttga aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc
    30901 cacgggtgta ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga
    30961 taggatgctt aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc
    31021 ttgttttttg acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt
    31081 tctcctccta ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag
    31141 gaaactgctg ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat
    31201 tgagataggg tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca
    31261 aaaagctgca atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa
    31321 tttgggatcg tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct
    31381 tcataaatct ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca
    31441 gtccaacgcc aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac
    31501 cagccaatcg gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat
    31561 tgagaaaata gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga
    31621 aagatagcgg ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa
    31681 ataaaaagtg ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta
    31741 aaaaaagctt ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta
    31801 aatgtcatat tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga
    31861 ataaaaacca tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg
    31921 aataaatctt tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa
    31981 agacaagaaa gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg
    32041 atgaaaaagc gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac
    32101 ttgtttttgt gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag
    32161 agcttcagct acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat
    32221 ttcagatgtc catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc
    32281 ttcttgataa gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt
    32341 cgcaagagtg cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc
    32401 tgaatcttct ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc
    32461 ttgcgctttt tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga
    32521 ttggttttct gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac
    32581 tgctcctgat tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc
    32641 ttctttcaaa agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat
    32701 cgtgactgtc tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct
    32761 tactcgacca aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac
    32821 atctcgcgct acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata
    32881 acctgcttct gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg
    32941 aacaccgtat attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc
    33001 ttcctttaca atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg
    33061 tatcctataa tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa
    33121 agcggtgttc agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt
    33181 ttcttcgttc tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc
    33241 ccacgcccag acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc
    33301 tgttaagaaa cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt
    33361 catttttatc cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc
    33421 aaaatttgaa aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata
    33481 aaaaaataca aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa
    33541 atggtgaggt ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt
    33601 taaattacaa gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg
    33661 atgatgaaca gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt
    33721 ttcaattaat agggactttt tccagtccgc tgaaagcgct tgatttttct ttggtacatg
    33781 caatcgatat cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc
    33841 ggctattaaa acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat
    33901 ttgatatggt taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat
    33961 tgagtcctga tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc
    34021 ccaacaaaag cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga
    34081 ttgctggaca aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct
    34141 gttatatacc gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat
    34201 cacccattca ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc
    34261 ggaagaatcc ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca
    34321 aaagtttcgt caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat
    34381 ccaagatatc aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta
    34441 tcataaggga aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga
    34501 gcagcaagca agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa
    34561 agaacttgag aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa
    34621 acatgaggca atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg
    34681 gaatgaagaa ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta
    34741 tttcgaagat ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc
    34801 aaatgcaaaa aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa
    34861 ttatgagaaa gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta
    34921 tctctcagcc atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt
    34981 ccgtatcagt aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg
    35041 tgagaaagtc ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg
    35101 aatgacacct tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag
    35161 catgaactct ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc
    35221 gtcatttctt tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa
    35281 tcgaatgatg tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc
    35341 gagaatacat tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat
    35401 ccagcccaac atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct
    35461 ctttcaaaaa tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga
    35521 acttttgtcg gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg
    35581 attgctcaga gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga
    35641 ttgactcttc gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca
    35701 ttgaatcacg tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt
    35761 tttcaatctg tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg
    35821 atcatcgcat caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta
    35881 acagtaggtg aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc
    35941 caggattgta cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg
    36001 atttttccga ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt
    36061 atgtatttgg atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta
    36121 gaggaagatg gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta
    36181 gggaatacga tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa
    36241 gacgaaaaga agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat
    36301 tttatttata atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa
    36361 gcagttcaag gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa
    36421 gaagtgattc cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt
    36481 atgcgatatg gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta
    36541 tctatgccga atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac
    36601 aataaaacgc aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc
    36661 gaagtgattg ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat
    36721 ttttcaggaa tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca
    36781 tatggcttaa cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg
    36841 cttcttccta aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt
    36901 tattttaagt taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact
    36961 gtcagcactg gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg
    37021 agcgcattct ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat
    37081 tctcccaagc tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag
    37141 ccaaaagctg ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg
    37201 acactcattt ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa
    37261 aaacgtgtct ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca
    37321 tgctgtgctg tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca
    37381 tacattgctg cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt
    37441 tctaaaaact gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt
    37501 gttgctggat tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg
    37561 acttctggat gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc
    37621 tctacaggaa cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg
    37681 atggaagcat acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg
    37741 aatgaacttt ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg
    37801 tatcgatgat cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt
    37861 cataccaaga aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag
    37921 ctaaaggtcg aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg
    37981 cctctaagta aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga
    38041 caatccctcc accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg
    38101 actccacttt tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt
    38161 ggatatgttc ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta
    38221 accctttacc gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca
    38281 tgagcttctc ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt
    38341 gaaacagctt cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc
    38401 agcatcatac cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc
    38461 ggcccatgga tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat
    38521 tcttctgcca ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg
    38581 atgatcgtga ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc
    38641 agacgcggaa tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt
    38701 aaatcagccg attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc
    38761 tccaacacat ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt
    38821 tggctttccg gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct
    38881 ggaacagtta tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct
    38941 tccactgtga tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt
    39001 tctttttcaa cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat
    39061 ttgacttgcg cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct
    39121 gtcacagtga ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg
    39181 cgtaaaggtt ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga
    39241 gtagtcgtaa aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag
    39301 tttcccatgt caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc
    39361 ttgatcacct cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta
    39421 ctcagacaat cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct
    39481 ccaaacatga tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt
    39541 aatccatgta tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga
    39601 taactggtat tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa
    39661 ctgatttgca gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa
    39721 gaaactcccg cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc
    39781 acatcgataa ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg
    39841 tctcgacttt cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg
    39901 atccattctg ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc
    39961 tgcttattgc tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg
    40021 atatctcgaa agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt
    40081 tctgcctgat tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt
    40141 atacggtcat gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt
    40201 tcttgcagtt tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca
    40261 ttttcaaata gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga
    40321 tgtccaccga caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta
    40381 ctgctgacat ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga
    40441 taagctaagg ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct
    40501 gtttcaaaat cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt
    40561 tttgactgac tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt
    40621 gccatagaag caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt
    40681 gccccctttt tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc
    40741 aacaagcgaa tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac
    40801 attttccgca acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc
    40861 tttgtaaggt tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat
    40921 gggtttcatg accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc
    40981 gcctagatta ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat
    41041 cacttctgag cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa
    41101 ggcattgata ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac
    41161 gtagcttcct aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt
    41221 atctccattt ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc
    41281 aacaactcgt acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc
    41341 aggtatttct gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag
    41401 ttcttccaga attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc
    41461 agaggaccgt tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa
    41521 atccgcgtgt cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac
    41581 ttctgctaca gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt
    41641 gacaggtgaa ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt
    41701 ttcgatcttc atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt
    41761 gatttcttct tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc
    41821 tggtccatgg gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt
    41881 tgaatgtctc tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga
    41941 tattcaattg gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg
    42001 gatgacttag atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag
    42061 ctgtcgatcc agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc
    42121 caatagctac tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat
    42181 ggccaattgt atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt
    42241 ccactacttt tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa
    42301 gatctttttc gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg
    42361 ctgatttgat gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa
    42421 cctcaggatc aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt
    42481 tgtttgtatt gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag
    42541 tcggaatttg aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat
    42601 cacccaccat tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg
    42661 ctaaaaaatc gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta
    42721 cgattgaaag gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat
    42781 atagtggagc aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt
    42841 gaagccatga tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt
    42901 tatcaacatg tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc
    42961 gagtgtctga atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga
    43021 gtaagtcttt tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg
    43081 gatctctacg atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac
    43141 aagttcccaa attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt
    43201 tttcatcaat gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg
    43261 aatcccacgt tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc
    43321 attaagccat tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt
    43381 tttaccgaca gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat
    43441 atcgctgtac tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt
    43501 cattccaaat tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg
    43561 gaaagcatat ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc
    43621 ggctttggcc attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc
    43681 agccatcgtc acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt
    43741 gccaggatgg aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc
    43801 tactccttca tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc
    43861 aatcactact cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg
    43921 atcgacgact ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt
    43981 ttttcccgct ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg
    44041 tggttttaca ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc
    44101 tttcctactt atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct
    44161 acagtgaaca tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata
    44221 gatgaatttc tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca
    44281 aacctggttt gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt
    44341 aatacgtatt cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt
    44401 aagaattgta cctagtatag acataaaaaa atcgactgtc aatcattttt atgaaacttt
    44461 ttttaatttt ctgatagtta actttgtttt tcagaaaaat aacaattggt tttattgaag
    44521 aaaatagtca tgaacaaaag tatctgagaa cttttttact ctcttgttca tgacatatag
    44581 aataaagcag ctttgtcttg taaactccgt ttttcaaata ataatctaaa gattgctact
    44641 gaataataaa gccgatttca tggtcctctt cgctgctgat tcggtaaggt gactcaacat
    44701 ccgctcccca gctattgata cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg
    44761 ttcgtctttc tggcggtagt tcttctatat gtgttgcctg ttccagttct tctgctttga
    44821 atggtaaagc ggaaaaagca aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt
    44881 cttgatcttt atccgtatta tccaacgttt gatttcttgt tagttctacc catttcgttt
    44941 ccatatgcat gccgcattct tggggaacaa ggtatgggga aacggggagt cctgccactt
    45001 tataaatacc ttcgacacca ccagccatcc gatccggata tgtttcccct gataggcctt
    45061 catactcaaa aaattttgct ttcgttggca taatgaacct taaacccaat gcgggtaatt
    45121 ccggtaatcc tttttgtcca taataatgca tattgacaag cattttaccc tctccagcga
    45181 tttggtagga aattgtcact tgggtttttg gtactgtgtt gatttccagt gtaaaaatga
    45241 tttcaaccgt ttcagcgtat tcattacttg aatattgatt atttactgga gcaatcggca
    45301 aatcgatctt tttattgtcc accagtactt ctatttcttt gacttttgga tacaatccgg
    45361 ctcctaacca cataccggat ttaaatccaa atccgctacc tctgtcatta tcggtcgttg
    45421 ctcgccaaaa aactggaagt gtttcccggt atagccattc ttttccgttt ttattgagcg
    45481 attccagtcc gcctcttgta taagaaaaaa tataatgcgt attccccgat ttgacaccta
    45541 atgtacagtc gccgaagacg attgcaactt tttccgtatc catatgactt ttatttactg
    45601 tatttttcat aataatatct tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa
    45661 acgatcccat tccctgagaa ttcatagtca cttggtttat cgtcaaagtc accgccatag
    45721 cgcatcactt ctctgcctgt gattggatca gtcacttgga tcgcctgatc tttaaaatcc
    45781 catatatagc ctccttggta catttcataa cgatcaagca acgtcatgta agaatccatt
    45841 ccacctaacg aattccccat gtcatgcata tattcacata agatgaacgg tttttccgct
    45901 ttattttcaa ggtagtcaat gatctcttct ggtggcgcat acatgcagct ttttacatct
    45961 gaaatcgaat cttcgaatgc tggatttgga aaattccctt cataatggac aagtcgatcg
    46021 gggtctactt ttttgaagta atcgttcatt tgtcgaatgt tttcttccgc ataagattca
    46081 tttccaagag accaaaaaag aatacttgga tggtttttta atgtttcgaa attcgttttt
    46141 gctcgatcaa gaacagccgc ctgccactga ggtactgcac ctggtacgtt gtaagaaggc
    46201 tcaaatgcgc ccattttttg ccatgagcca tgggattcga ggttcgtttc cgccatcaca
    46261 tggattcctg cttggtcgca taaataatac caagtgatct ggttggggta atgagatgtc
    46321 cgtacgccgt tgatctttgc attttttatg atagccaaat ctttttccat atcttctata
    46381 gtgatggcgc gtcctttttt cggatgccac tcatgtcgat ttaccccgtt gataatcatc
    46441 cgttttccat tgaagtagat gattttatct ttgatttcga ttttacgaaa accgaaggaa
    46501 tagtcaatat actccgttac tcttttttct tcgtctatcg tctccaattc aagcttatat
    46561 aaattgggct gaaaatgccc ccacagtgcc acattttcaa atccatcgat gcgaatcgtc
    46621 atttgctctt ttaacggata ttgctgttga tagatttcct tcccatcagg atctagtatc
    46681 gctacattca gctgactgtt tttggctact tgctcaaaag acaaatctac ttcaagtttg
    46741 ccattttgac atttgtcatc taagcgaggt ttgatccaaa gatcttctaa atggttttgt
    46801 cctcgagcaa ctaagaagac atctctgaag atcccaaaaa atcggaaaaa gtcctgatct
    46861 tccaagaatg cagctgtact tcttttgtaa acctccacag ctagaatatt ttcttcttcc
    46921 aaataaggtg ttaaatcaaa ttcagacgga gtgaacgaat cttcggcata cccgataaaa
    46981 tgaccattca accaaataaa cattgcttgt tctacaccag caaaatgaat cgagatttgt
    47041 tttcccttta gaccttcttc taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct
    47101 ttagcagctg aaaagatccc ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg
    47161 cgaaatacat gtccctccca cggatacatc gtattgatgt aatggatctt gtcataattt
    47221 gctaattcaa tatgactagg aacagtgatt tcatcaaaag aacaggcatc aaaatctttt
    47281 ttataaaatg tttttggtcg taccgaagga tttggcgaat aacaaaaacg ccatgatcca
    47341 tttaaagact gtttaaggga ggatgtggtt tctacttctt cccttgttgc ataacaaaca
    47401 tgatcgctat gtgcatttga ttggttcact ctaaaaactt gtggatcatc taaccatttt
    47461 atatttgctt tcatactttt ttccttctct ctcataactt tttgaaatga agcagttctg
    47521 tttggaaatc accttgaaaa tcggggaagt aaagtccaac tgtcatcaat tcggcccccg
    47581 aaaatatccg cttcgaggtc tgttcctgat aaagtgcctc atcatctaac cccatcagat
    47641 atacttcatg gaacgctggt tgagctgaag ctagtatcct ccctaaaaac acaatagctt
    47701 catcttgttt aggagacaca aacatccatg cggcaatatt ttcttcaaaa ggactcgcca
    47761 aacgataata atggccatac tggatcaccg gacgaatcgt ttgataggat ataatttggt
    47821 cttttacttg cttttcttct tcaggagaca gctttgtcaa atccagttca taaccaaaaa
    47881 cagcgctcat agctgtttct cctcttgttt tcaacgaagt agatctgtcg gtctgatgat
    47941 ttggtacagc tgatacatga gctgtgatgg acgaaatcgg ataagcaagg cttgttccat
    48001 attggatttt catacgctcc actgcatccg tgttatcact tgtccatgac tgcggcatat
    48061 aataaataaa cccggcatca aaccgtccac ctccaccaga acagccttcc cataagattt
    48121 ccggataatc agttgtcaaa tgttcaagta gttcataaag cccgagcata taacgatgcg
    48181 ctacttctcc ttgtctctgt gggtcaaggg taatcgaata gacatctgaa agcgaacggt
    48241 tcatatccca tttgatgtag tcaagaggaa tcgtatctaa aatctttctc atttgtttct
    48301 caatcgtctg ccgaacatct aaccttgtaa aatccagtac atgttgtgat ctggaagcag
    48361 aaggcattct acctggctcc tgcataagaa aatcaggatg tgttcgatac agttcagaat
    48421 caaccgagat catttcaggt tcaaaccata aaccaaattt caatcctttg ctatgagcat
    48481 aatctgctat ttcacgtaat ccatttgtca acttgccttc atactcgaac cagtctccta
    48541 atgaagaatt gtccgcatct ctttttccaa accagccatc atctaatacg aacatttcga
    48601 tgcctagctc ctttgcttca tcaatgatcg ccttgatttt ttcactattg aagtcaaagt
    48661 aagtggcttc ccagttattg accagaatcg gccgttcagc aaattgatga cgacctcttg
    48721 cgattctttc acgtagcaac tcatggtgga tctgactcat tttgttcaat ccctgacttg
    48781 agtaagaaag gatcatttca ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa
    48841 aacgatggct gttgatccca ccgacgactc tcaattgatt gatctgatct ttttcaagtt
    48901 cgaaagaatg gttgccggaa taaacaaatt gaagtccgat cgcttctcca gtattttctg
    48961 tcgtatgatg atgaactaaa gcaataaagt tattcatatg gtgactgctc gttcctcgac
    49021 ggctttcaaa tacttttgtt ccagataaaa cagattgccg tgaaatctgt ctttcattga
    49081 catgtgctcc tggcaaagca atgacttcat caaatcgcct agtatgggca aagtctagct
    49141 ggaaactagc cgctttttct agtttgattg tttctccggt ttcatttctt atctttacag
    49201 atcgtgtgat cactgctcta tcagtaaata tggtatagaa caaatcgaaa taaatcgctg
    49261 tttctctatc cttaagtgaa atcaccaacg tttgtgcctc tgacttgtcc atcacataag
    49321 tttgaggcaa gccttcgatc tctggcttcc catctgtaat ataatggctg tcatatctca
    49381 gatccagtaa gtctgatcca ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca
    49441 tgctgccatg agaagagtat tcttgcggta gtgtatcttt cgacagagac cggtcaggat
    49501 ttaagggaac atttcctgaa aatccacgat ctcttcgggg ataattttta ttgtctttgt
    49561 actgcttgac tggtttgcca aaataaatat gcgccaatac attgctttct tctatcttta
    49621 tcagataaga aagaaatgta tttcgtaaat ggaagactcg gctcttttca tcaaataaga
    49681 tgaaattttt atctgttttt ctatgcgtaa tatccatcat ttcactccca acaaaacgga
    49741 aaccgtttac ttttttttat aattcctgta tactgtttac taaacaattt tgtcaataaa
    49801 aattttttat ttttttgagg agtgtgtaaa aatggttgga attagagatg tcgcacgaaa
    49861 ggcaaatgtc tctcctgcta cagtttcccg tgtgttgaat aacgatcaga cgatccatgt
    49921 ggctcagact actcggcaac ggatagtaga ggcagctgct gcgttggatt atgacatcag
    49981 tactcgtaaa tatatcaaaa agagaatgcc ttcgattggt gtgatctcta cgatcggcaa
    50041 agcgagcgaa gaacaggata tctattacaa acatttgcga gtagggatgg aagaagaagc
    50101 tcgacgtctg catttaggga tgaatcgaat ctataatcta tctgataatc ctaaacaatg
    50161 ggaagatcta gatcagttag gtgcggtgat cgttgttggg actgttacga aagaatcgat
    50221 taccgccttg ttaaaacaaa acatgcaaat agtcgtcgtg gataaccctg acatccagca
    50281 agaggtcgat atggtgtatg cagatcttga acggatgact aaaaccgtac tggaattgtt
    50341 cttagaaaat ggtcataaaa gaatagccta tatcggggga tataaagtcg atatggatga
    50401 attcggtggg aagcagattt ctataaatga aaagaggatg cgtgcctatc agcattttat
    50461 gatcgatcat cacttagaaa aatatatgtc ttatcatcta ggtggctgga cagaaaaaca
    50521 aggtgaggta cttgcgacta atctattaga aaatgaatcc cctcttccta ctgccattct
    50581 tgtcgggagc gatccaatgg caattggtgt ctatcgggca ttgaaacaaa aaaatatcca
    50641 aattggagaa gagattgttg tagcaagctt tgataatatc gagacaatcg caaacctctc
    50701 ccctggcttg accagtgttc aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat
    50761 ggcattggag cgaattgacg gtatacggga cgaaccaatc attttgactt atcctgcacg
    50821 attgattgtt agggaaagtt ttatcccaag aacaaaaagg tattgaaaga gaggttgtga
    50881 aaagccgctt cgtttcttca tactcaaaac gaaacggctt tttcacaacc tcttacttat
    50941 acttattcac aaaatccaat gtctgctggt aacaattttg cgattctttt agcgtgtaat
    51001 caaattggta ttcatgggta atctcttttt ttgtatctgt ataaaacaag gattgcacgg
    51061 gtacctttaa ttatgtcaac cgattttcta atgcttgacc ttgctcctgg aatgagtatg
    51121 catttccgtc agttatatac gttggcggaa attccttaga aacatggtca gccacactag
    51181 cttctttcaa ttgctcactc gttttccaat cttttgttcc aatcaacgac cacgcaacgg
    51241 ttttgacgaa aaacttcata aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat
    51301 caacaggtcc gcaataagaa atggttcctt tcagactatc ttttggaagt agctgtttga
    51361 ttttcatttg tttagcatac gcatcattcg tttgtatagc tgcatattgc aatgcgattt
    51421 gtgaacctgc actatctcca ccaaaaaata attgttccat gtctagcaat ttgtcgtctt
    51481 tttcttcagc taataaatct ttgatcagtt cattcacttg aagaacttga ttagggtatt
    51541 ctgaatcagg cgctaattca taattcatcg caaccactgc gatgttggcg tctgaaacta
    51601 attttgtcgc aaattctttg acacccgatt tatctccgcc gacgaatcct ccaccatgta
    51661 cccaaaatag aacaggaaca ggccccttgc tgttttttgg atagtagatg tcataagtat
    51721 tctctttata cttggactca tacgtcaaat ctgttttttt cgccacgttt ttttctgctt
    51781 gatcgaacgt ttttttatca gtgatttgaa cagtatttga aaacatatgg ttgatcaaga
    51841 atgctccagg tctgggggaa agctggaagg caagaaagat tgcaaacgcg atcccaagaa
    51901 tgattccgaa gaaccatccg ataaatttaa gaattttctt tttcataagg ctccctcagt
    51961 agttagtatt aagcattctg attataccat agtgttattt cctatcaagc tctcctagat
    52021 gatttaatga ttttccccaa acttcttctg caatgctttt gacaaaagaa attttttcca
    52081 ttgttcttca aacaaaacat tttcttcttc tgttgaagca aatccacatt gaggacttaa
    52141 gcacaaacga tccaaaggca gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg
    52201 gtgctcttcc atttcgccat ttttcgttac agtcaaaatc taagacaact aatttatctt
    52261 cagagacttt ctctaaaaga acaaaactcc cagcacgttc actatcgtat tctaaataat
    52321 aggcacggac attttcttga gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg
    52381 ccgccaaaat cgaataataa tttccgcgtc aaacatgtat atttagtgtt gaatcatttg
    52441 agaatatgaa aataaaaatc tttttgatca atcagttaat caaattgaaa taacgaaaaa
    52501 tctgagacag aatgacgttc attctgaccc agatttgatt ttgcacaact caacagtcct
    52561 tattggcaaa tcgccaaaat aatgtagact aactaaaaag actaagaaac aataacaaaa
    52621 gttaacactt cttagtcttt ctttagcacg tctatttatt aaagatttta gggccttttc
    52681 tcatgttttt acgatcattc ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt
    52741 tctttttgat caattctttc attttttctt tttggtccat ttttattctc ctttaacgaa
    52801 tgaagcgact aattcgatat gatgggtttg cgggaaaaga tctacaggct gaactttctt
    52861 cacggcataa cctgcttctg caaataactt agcatctctt gcaaaagttg ccggattaca
    52921 tgagatatag acgattcgtt ctggtgacat ttcgattgct gattcaataa aatgatgatc
    52981 taatcctttt cgtggagggt caactacgat cacagatggt ttgatccctt tttcttgcca
    53041 ttttttcata actttttctg cttttccgac ttcataatga acattttcga ttttattatt
    53101 taaagcattg aactgtgcat cttcaattgc ttctggaata acttccatcc catacacctt
    53161 atccactctg tctgctaaag acaagccaat cgtacctatt cctgaataag cgtcgatcac
    53221 aatgtctttt ttatctaact cggcaaactc gatggctgtt tggtacagat actctgcttg
    53281 ttgagtattt acttgataaa atgactttgc tgagattcga taggtttttc ctaatagctg
    53341 atcttcgata tagtctctgc catataaaac tttttctttg tctcctaaaa tcacatttgt
    53401 tttttcttca ttgatatttt ggatgaccga aaccacttct ggcaattctt catgaatagc
    53461 ttcagcaatt tccttggatt taaagaattt ttctttacga gtaactaaaa cgaccatcat
    53521 ttcatgggaa taatgaccac gacggataat gatgtgacga agctgtcctt catttttttc
    53581 ttcattatat cctcgtactt ggaaccgttg caagatatct ctgactactt tgattgcttg
    53641 atcgatgaca ggatcttgga tataaaaatc ttcgataggg actagatcat ggctattctt
    53701 tttgtaaaaa ccggtggcta actgtccatc gatacggcga acagggatct gtgctttatt
    53761 acggtagccg aatggttctg ccattccgac cgttggaagt acaggaactt ctggcatctt
    53821 agcaatcttc gccattacat gctctacttg tttttgtttg aagacaagct gttgttcata
    53881 cttcaaatgg gctaaaggtg cgatacctat gcgaagtaat gcattgtttt ctacaggctg
    53941 acgatcaggt gattgtgtaa taaatgtttc gacttttcca tatccaaact tattgcctgc
    54001 ttttactact agtatttcta cttcttctcc agggagtgca ttttcgataa ataatggata
    54061 accatcgatt tttgctaccc ccattccttc ataactcaag tcgacgattt cgactgtata
    54121 tcgttcgttt ttctttacta tttgctgttc tgtcatattt tgctccttta agcctatttt
    54181 tcaatcctac tgaactctac tataaatcag ctaattacac aactaaaacc ggcactgacc
    54241 ttactacgtt cagcaccggc ttttgattaa ttcttttgat taggtgtttc gtctgctatt
    54301 tttccgtcac cgtcgatatc ttcatccgtt aaacgttcga cttcttttac gaattctttg
    54361 ctgacaacct ctaattcttc ttcatctgta cctgtgattg cttcatcagg aatctgatcg
    54421 gtattggcaa agaactcaat gtgttgatga agattttgga aatgcatcgg tgcttccccg
    54481 ccgtattcac catctaagtt gatcattact ggtcgattga tatcatcttc tgtttcaacg
    54541 aacaaactgc ttgttttggt atagattatt cttggatcat cgacatgtcg accgccattc
    54601 agcatgagtg ctgcaatatg caagatctca aagatatttg ctgtcttcac aatgattaaa
    54661 gaaaacttcc catcatccaa tttggcatct ggcgcgatct gttcgaatcc tccaacagag
    54721 ttcgtcagcc ctaggaaaaa catcgaagca tttccgatat attccccttc atcatacttc
    54781 aagcgcattt tgattggctt tactcgaggg agcatctctg ctcctttcgc aagataagca
    54841 agataaccaa aaatactctt tagttctgat ggaacttcat aagtcaattc tgtcaaatag
    54901 ccacctgcag cgatattgat gaagtaactg ttatcagaaa ggccgatgtc catttttacg
    54961 gtttggtgtt tttttatcac ttctgctgct gctttaatat tatctctagg aatttttaat
    55021 gctcgagcat agtcgttcgt tgtaccagct gggatgatgg ccattttagg acggtgttca
    55081 agcggagcga ttccattaac cacttcgttg attgtgccat cgccaccagc tgccactact
    55141 agatcaaaac ctagttctgc gactctacat gcttcattct tggctgaatc tggttctggt
    55201 gtagttgcat aggcgctggc ttcaaatcct gcttcttcta atgcctgtag gatatccgcc
    55261 aaattttttt tcaataattc ttttcccgag gtggggttat aaattacgcg tgcttttttc
    55321 attttcagcc tctatcgttt cgctaattca tctttaagta gcttattcac gacaccagga
    55381 tttgcttgtc ctttagttgc tttcatgatt tgaccgacta ggaagccaac cgcacgatct
    55441 tttccatttt tgaaatcatc gacagattgt tggttgttat ccaaaatttc attaatgatt
    55501 ggcagtagtt tgttcggatc agataattgc acccaaccat ttttttcaac tacttcttgg
    55561 gcttctccgc catttgtgat caattcacgg aagacttttt tggcgatttt tgagctgatc
    55621 gttccatcgg cgatcaaacg aatcattcct gctaagttct caggtgtcaa ttttgtctca
    55681 gctaattcca gtttctcact gttcaagtaa gcagaaactt cacccatcaa ccagttagat
    55741 gcttgcttgg catctgcacc attttccaaa acagcttcaa aaaaatcaga catttctttt
    55801 gtaagtgtca ataccattgc gtcatactct ggaagtccaa actcacggat atagcgttcg
    55861 cgacgagaag ctggcatctc aggcaaacta gcttttactt tttgaatcca ttcgtcatcg
    55921 atcacgaatt tcgggatatc aggctctggg aagtaacgat aatcactaga cccttctttg
    55981 acacgcatca aaactgtttt attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt
    56041 tctcctcctg aaagaagaac ttttgcttga cgtttttctt caaaagctaa accttttttc
    56101 acgaaagata aagagttcaa gtttttcaat tctgctttcg taccgaactc ttcttgtcca
    56161 taagggcgaa gagaaatatt ggcatcacag cgcatagagc cttcttccat tttcacatcg
    56221 ctgacttctg taaattggat aattgatcgc aatgcttcta gataagcgta tgcttcttct
    56281 ggtgaacgca tatcagcttc agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa
    56341 tcaacgtaag aataaccgcc aataccatgc atgttttttc cagcatcttc ttctaaatgg
    56401 acacgttcga tccggatttt tttcttttta ccttctactt cgatttcgat ccatccgtca
    56461 tgaccgattg gttgatcaaa ttgggaaatt tgatatgctt ttggattatc tgggtaaaag
    56521 taatttttcc ggtcaaaatg agtatcttta gagatttcac agtttaatgc caaagctgct
    56581 ttcatcccga attccagcgc agctttattc attactggca gcacgcctgg ataaccccag
    56641 tcgatcacgt ttgtattgct gtttggttct gcaccaaaat gagctggcgc tggagagaaa
    56701 atttttgagt tggtttttaa ctcgacgtgg acttctagtc caatgactgt ttcaaaattc
    56761 attcgtcttt ccctcctaaa atagctggtt gttgtttatg gaattctgtt gcttgttcaa
    56821 acgcatatgc cgcttgatac atcgtttttt catcaaaata attaccgatg atctgcaatc
    56881 caactggtaa tccttctgat aaacctgccg gtacagacat acctggaagt ccagccaagt
    56941 tgacagggat cgttaagatg tcactcatgt acattgtgat tggatcgtta atgttctcac
    57001 cgattccgaa tgcaactgtt ggtgaagatg gcccgatgat caagtcataa tctgcaaaga
    57061 ctttttcaaa atctcgtttg atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt
    57121 cataataacc cgcgcttaag gagaatgtac ctaacatgat acggcgtttt acttcttcac
    57181 cgaatccttc tgaacgtgag ttgacatata catcatctaa tgatttcaca ttttcagagc
    57241 gataaccgta gcggatacca tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa
    57301 tgatataata aacagccaca ccgtattttg aatgaggcaa gctgacttct tccacaacag
    57361 cacctaatga acggaatgtt tctgctgctt tcaatacagc ttcttttacg ccaggggcca
    57421 caccttcgcc taagtattct ttaggtaaag caatcttcat tcctttgatg tcgcctgtca
    57481 gtccctctgc aaaatcagga actgaaacgc ctgaagaagt accgtctttt tcgtcataac
    57541 cgctgatagc tgtcaatgct aatgcattat ctttcaccgt acgggtcatt ggtccgattt
    57601 ggtcaagaga tgaagcaaag gcaatcaaac caaaacgtga gacacggcca taagtaggtt
    57661 tcatccctac gatgccgtta aaagctgctg gttggcggat acttccccca gtatcactac
    57721 ctaaagaaac tggaatttgt ccagctgcaa ctgctgctgc agaaccacca gaagagccac
    57781 caggtacttt tgttgggtcc caagcatttt ttgttttctt gaaataagaa gtttctgtac
    57841 ttccacccat agcaaattca tccatgttta gcttaccaac agggatcata tctgcttgat
    57901 agattttatc catgaccgtt gcatcataaa ttggttcaaa attgtaaagg atcttagatg
    57961 cagcggttgt caagatatct tttgttacga tattatcctt gataccaatt ggaataccag
    58021 caaggacgtt gctttcatca atcccttttt catctaaagc ttttgcctgt tccaatgctt
    58081 tttcttcgtt caatgtaatg aatgcctcga cctcaggctc tgtttctttg attcgttcaa
    58141 atgttgtttt tgtcaaatct tgtacagtga tttctttcga tacaagcata tgatgcagtt
    58201 cttctagaga acgattgtgt aattctgtca ttatgcgcca gcctccccat tatcgatgat
    58261 tgcgggtact ttgataaagc cgtcttctgt ttccggcaca tttttcaata attcatcgcg
    58321 gttccatcca gcttgcgccc gatcttgtcg catcacgttt actgtttcaa ccacattcga
    58381 cgtaaatgga acaccttccg tatctacttc ttccagcatt tcaaccatat cgatgatttt
    58441 acctaattgg tcggtaaaac ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt
    58501 ggcaacgtgt ttcacttgtt cttcactaat cgccatacta ccccttcttt ctaaacgagt
    58561 taaaaacttt gctctctatt ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat
    58621 ttgtctgaaa aaactcattt ttcattcttc tactgagcga cttttagcca atgcatctgc
    58681 catttgatct tctgtccaaa cttcgattcc taattcttgt gctttggtca gcttgctgcc
    58741 agcatcttct cctgctacca cgatatccgt ttttttcgat acgctaccag tcactttccc
    58801 gccaagattt tcgatcgtct cttttgcttc ttcacgagta aatcgtgtta gtttaccagt
    58861 aaggactact gttttttctt taaaaggaga ctcgacttct tgcaattggg catttcgaag
    58921 ccctttgtat tcgaaattga cgcctgcttg ttttaattca ttcatcaatt catggacttc
    58981 ttcgttactg aaataagtga ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc
    59041 aataatcgac tcatagtcac ttttactcaa tgtttctaga tcaccgaaat gttctgctaa
    59101 aatttttgct gctttcgctc cgacatgtcg gattcctaac ccgaaaatca accgctcgac
    59161 cgaattatct ttgctgttgt cgattgctgt caaaatatta tttgctgatt tttcttttat
    59221 tttgtccaac gtcaataact cttcttctgt caatttgtaa agatcagcaa catctgctac
    59281 tagtttttta tcatacatct gttctagtac gcgcggcccc aacccatcga tattcatcgc
    59341 atttcttgaa acaaagtggt tcaaaccttc tttcatttga gcagggcatt taggattgat
    59401 gcaccgtaag gctacttctt catccaaatg gacaagttca cttccacaaa ctggacaatg
    59461 tgtaggcaat tggtattctt cgctgtcttt aggtcgttta tctaacacga cttgcgaaac
    59521 ttctgggatg atgtctcccg ctttataaat cagaactgta tctttcaagc ggatatcctt
    59581 caacttaata taatcaccgt tatgcaggct ggcacggctt actgtcgttc ctgctactcg
    59641 gactggtgtc atgatagctg ttggcgttac tacccctgtt cgaccgactg tccattcgat
    59701 gttttcgatt agcgtttcaa cttcttctgg cggaaacttg taagctgctg cccatctcgg
    59761 tgctttgata gtaaaaccaa gttgatcttg tagcgagaat tcattcactt tgatgacgat
    59821 tccatcgatt tcatagggca aatccacacg tttgtcatga tattcttcaa tgtatgacca
    59881 cacttcatca atcgaatgac atagacgttt ttcccgattc gtgtggaatc caattttttc
    59941 tagctcttct agcgcatcat actgggtttt tgcttgcata ggaccgaaat cagctactgt
    60001 gtataaaaaa gtgtccagat ttcttttcgc tgtgatttta gaatctaact gacgcaaaga
    60061 accagctgcg gcgttccgag gattcgcaaa gatatctttt ccctctgctt ctctgtcttg
    60121 gttcaattgg acaaatgacc gttttggcat gaaacattcg cctcttactt cgatgttcat
    60181 tggttctttt aatttgattg ggaccgaccg gacagttttt aggttttcag tgatgttttc
    60241 tcctacagtt ccatccccgc gagtcgcacc tctcacgaaa tttccatctt cataacgcaa
    60301 agaaacggaa agtccatcta tttttagttc acagcaatag tcaactacac gtcccactgc
    60361 tttttgtaca cgttgatcaa aagctatcag ctcttctttg ctgaaaacgt cgttcaaact
    60421 gtaaagcgga atatcatgag tgactttttc aaaaccttct aatacttttc cgcctactcg
    60481 ttgagtggga gaatcagacg tgatcaaatc aggatattgt tcctcgattg ctactaattc
    60541 tgcgtattct ttatcataaa catagtcttc cactgttggt ttatcttcta cgtagtattc
    60601 gcgagaccat tggttcagtc ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat
    60661 cgtcatttca tgttccatca tttaccctcc actactaagc tttttcaatt ggcgcaaagg
    60721 cagccaaaag acgttttact ccttgacttg ggaaagccac atctagttct agatccttcg
    60781 acgtcccgct tactcggacg actgttccta gaccccattt tttgtgtttg actttatctc
    60841 caggtttcca gctgttattt tcccctccag tagcactttt agagggaaca accgctgtct
    60901 ctggctgttt atagctatat gctgtttttt tagcgaatac aggcgttttt ttaggcgtag
    60961 gacgcatgcc ttcgatttcc agtaactcct gatcgatttc ttctacaaaa cgagaaggtc
    61021 ggttatattg cgtccgtcca tataatgttc tggagaaagc atttgttaaa tacaacgctt
    61081 cttctgctcg cgtgatcccc acatatgcga gacggcgttc ttcctccagt tcgctttctt
    61141 ccatcaatgc tcgagataaa ggaaaaaccc cctcttctag accaatcagg aatacaactg
    61201 gaaattctaa tcctttggct gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt
    61261 ctaaattgtc aatgtcggaa acaagtgcca gatcatttaa gaagaccgtt agtttttctt
    61321 ctggtgcatc agcgtcttct tcattttgct gttcgaattg tttgtcgaat tcttgtgtga
    61381 ccgttaaaaa ttcctccaag ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt
    61441 ttaagtcttc tagatatccg ctacgatcca aaacctcttt cgtcaattct gtcactgtca
    61501 agtatgggat catctgagtg acttcttgga tcatctctcc aaatgcacct aattgctgtc
    61561 ctgcttttcc accgatattt gccagatcca cattttgcgc tgcttcaagc agtggccatt
    61621 catgaagaga agcaaaactg cgtagttttt cgatagatcc tggtccgatg cctcgtttgg
    61681 gcgaattaac gatacgctca aaactgattg aatcttgagg atttaccagc acattcaaat
    61741 acgctaaaat atctttgatt tctttacgat cgtagaactt gtgccctcca accattttat
    61801 aaggaatatt tgctttcaac agagtttctt ccattacacg agattgtgcg ttcgtccggt
    61861 acaagatggc aaagtcgccg taattccgat gattgcttcg aatctcttct tgcatccggt
    61921 ctacgataaa acgggtttcg tctcgttcat tatctgcacg gtagtaagtg atcttgtttc
    61981 cttctttgtt ttctgtccac aagttttttg gttttcgatt gctattgttt tcaatgactt
    62041 ggtttgctgc gctaaggatg tttttcgtgg agcgatagtt ttgttctagc aaaattactg
    62101 cagcatctgg ataatctttt tcaaaatcca agatgttctg catatctgca ccgcgccagc
    62161 cgtaaatact ttgatctgca tctcccacga cgcacaggtt cctaaatcta cctgccaata
    62221 aattgactag cgtatactgt gcgtgatttg tatcttggta ctcatctaca tgaatataat
    62281 ggaatttgtt ttgataatac gtgagtgaat caggatgttc ttcaaataat cgaatcgtat
    62341 tcatgatcag gtcgtcaaag tccatacatt gattatattg aagctctttt tggtaagcag
    62401 cataacattt tgccgcaatc tcttcgtaat aactgccttg catttttgca aaatcctgag
    62461 gggtctgcag gctgtttttt gcttgagaga ttgttcctaa tatacttcga ggatcatatt
    62521 ttttcggatc aatgttcagt tcttttagta tccgtttcat caaggtcagc tgttcagaag
    62581 aatcgatgat tgtaaagttc cggttatacc cgataaaatc aacatctctt cttaaaatac
    62641 gcacacacat cgagtgaaaa gtcgataccc agacatcttc gcctccagat gcgagaatcg
    62701 cattgacacg ttctttcatt tcttttgcag ccttattggt aaaagtaatc gctaggatgt
    62761 tccaaggatt gacttctttt tcctcaatca aataggcaat gcggtgtgtc agcactctcg
    62821 tctttccact tcctgcacct gccattagca gtaatggtcc gtcagtgtga agaacagctt
    62881 ctttctgacg ggggttcatc ccgtttaata attcagcttt ggatgacatt aacaacatcc
    62941 tttcttttat caatcttgtt aattatagca ttttcttggc tttcattaaa ctagctagtt
    63001 caaaatcatt tgtttctttt tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa
    63061 ttaaaagaaa gcgaggcgtt tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga
    63121 ctcagatata ttttattcta aaaggaatat ttgttggact gctgacagga atcgtcgtta
    63181 gcctgtttcg attatctatc gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga
    63241 gtcgggaaca gccgatttac ttaattggcc tagctatttg ctgcatcctt gcagcatttt
    63301 tcgtgggtta tctggtcaaa aatgaaccgg atatcaaggg aagcgggatt ccacaagtag
    63361 tgggacagct tcgcggggaa ttatcaatga actggttctc tgttttatgg aaaaagttca
    63421 ttggcggtgt actttcagtt ggtgcgggcc tttttctagg tagagaagga ccttctatac
    63481 agcttggcgc atccattgga caaggagctg gacaattgtt tcggagtcca tcttcagaag
    63541 aaaagatttt aatttctagc ggtgcaagta gcggacttgc agcagcattc aatgctccta
    63601 tcgcaggatt actctttgtt ttagaagaaa tccatcactc cttttctcca cttgtttggc
    63661 tgacatcatt tgcttcagca atcactgcta acttcgtctc tctttacttt ttcggcttga
    63721 gacctgtttt atatctaggt gaccttcctt ctttgccgtt gaaatattat ggttccttag
    63781 tgatcttagg agtacttcta ggcatcttag gttttattta tcagaatgtc ttgctggctt
    63841 tgccaaaatt ttacaaccga ttgcctttac cagcttattt tcacgggttc gttcctttct
    63901 tgctgatttt gccaattggt tatttatggc ctagtactct aggcggaggc aatcaaatcg
    63961 ttttagcttt tggacatgct tccttgccaa tcattatgat tatcggtttg tttgttcttc
    64021 gattcgtttt ttccatgatt tcttacggtg ggggtcttcc aggggggatt ttccttccga
    64081 tattgacatt gggggcttta atcggtagct tttatggaaa cattatggtt gatttcggga
    64141 tggatccaat ctacatcaag gattttgtcg ttattgccat ggctggttat ttcacagcga
    64201 ttggaaaagc accgctgaca gcaattattt tagtgacaga aatggttggc tctcttaatc
    64261 atctgatgcc tttaggattg gctgctcttg ttgcttatat cgtcaatgac cttctcggcg
    64321 gtaatccaat ttacgaatca ttattggaac gtctacttgg aaatactcag accgcctcac
    64381 taaaaggtgc aaggacaact tttgattttc cagtaacggc agagagttct ttagacggat
    64441 taatggtacg agacttcaat tggcctaaaa atatgctgct aatctctata cgcagaggaa
    64501 atcaggaaat cttgactcac ggtgatacga tcatgaatgt aggagatatt ttggttatct
    64561 tgactgatga agcaaacttg ccaagaatca agcaggaaat cgaggctaaa tcttctatca
    64621 caaatttgaa gcaatcattt taacgaacat ggaaaaacta ttttacaaca actattcatc
    64681 tacactactt gattctatat gattctataa aaaaagaaga ggctgggaaa acccagcctc
    64741 ttctttttta tttctatgct tctgctactg caggagcttt tctcaataaa ccataaatca
    64801 caccagatac gactgctccg atagcaataa acaccaaata catgaccggg tgactcagta
    64861 agaatacaac gaaaatcccg ccgtgaggag ccagtaattt gattccgaaa gctccgacta
    64921 atccgccagt taaagcagaa ccaataataa aacttggaat ggcacgaatc gggtcagctg
    64981 ctgcaaatgg aatcgatcct tccgtgacaa acgatagtcc catcacgatg ttcgtcaaac
    65041 cagcatcttg atctgttttg ctgaatttat tcttaaacaa acgtgtagca acgaaaattg
    65101 ccaatggagg taccattcct ccagccataa cagaagccat cacgacactt ccgccagttg
    65161 caacagtcgt agctaaagtt gctgtaccaa acacataagc ggctttgttg attggaccgc
    65221 ctaaatctgc cgccatcatt ccagctaata atgcaccaag taaagcagca ttcgaaccac
    65281 tcatacttgt caagaaaccg ttcaatgcat cattgattgc tttcataggg acattgacca
    65341 gcaacatcaa gaaaccagta atcagtaagc caaacactgg ataaaagagg atcgttttaa
    65401 ttccatccaa tgattttggt aagttcttga ataatttacg taaaaatacg atgacataac
    65461 cagctaagaa tccaccaatc agtgcaccta agaatcctgc accgcctgta ttagctaatg
    65521 caccagcagc aaatccaacg atcaaaccag ggcggtcacc gatacttgaa gcaataaatc
    65581 ctgctaatac cggcagcatg aaaccaaatg cagcttgtcc gatttggttg aaccagctag
    65641 cagcttgatt gtaattccct agatttgata attgatcatg tggcacgcca ataaattggt
    65701 cgatcatgaa agaaagcgca atagcgattc ctccaccaat aacgaaaggt aacatgtgtg
    65761 atacgccgtt catcaaatct ttgtaaattc tttgtccgat agtaccatcc gcatttcctt
    65821 cttctgaact gctttctttt ccatcaccat ggaatactgg tgcagtacca ctaagggcta
    65881 gattgatcaa ctcttctggt ttacggatac catcactgac aggacgattg atcagttctt
    65941 ttccgtcaaa gcgattcatc tctacttttt tgtctgctgc aacgattaca ccttctgcac
    66001 gggcgatgtc ttcagcagtc aatcggtttt tgattccttc tgaaccgttc gtttcgactt
    66061 tgatctccac acccatttct ttcgcttttt tcttcaaagc atcttctgcc atgtaagtgt
    66121 gagcgatccc tgttggacaa gctgtaacgg caacaacgaa ttttctttct ggatgagcag
    66181 aagcttctgc agcttgtgtt tcttgttctg ctttttcttc tgcttctttt tgctcttcag
    66241 ctgtttggaa caagtcttgg acttcttctg gtgtatttgc ttcttttaat tttcctacga
    66301 aatctgcatc aatcagcaat cgagatagtg ctgctaatgc ttgcaaatgt gtgtcgtttg
    66361 cgccttctgg agctgcgatc atgaaaaaca gataagttgg ctgtccgtct aaggcttcat
    66421 aatctactcc tttttggctt tttgcgaata aaactgttgc ttctttaact gcactgtttt
    66481 tcgcgtgagg catggcgatt ccatcaccaa gacctgtaga agtttgtgct tcgcgggcta
    66541 gaattccttc tttatatgtt tcgatatcgg aaatccggcc ggcatcaaac attttttgga
    66601 ccatttcatc gattgcgcct tttttatcag tcgcttgcaa atccatgatc atcgcttctt
    66661 tgaccattaa atccttgata ttcatgatta tcctccttga aactaatcaa tttttgtgat
    66721 ttcaacttct ggcagcaact catcaatcaa ttcgcgagct gccaagtcat cagaaaaagc
    66781 tgttgcgctt ccgcaagcaa ctccccattt aaaggcttcg attggatctt tcgtacggct
    66841 gtaagcccca ataaagccag caatcattga atcccctgca cctactgaat ttttcaatgg
    66901 gcgaactaat acattcgttt tataagttcc ttgttccgtg aagagcaaag caccgtctcc
    66961 agccattgag atcagcacat tctgtgcccc ttcagctagt aattttttcc catacggaat
    67021 gatttcttct acagattgga aggttgtgtt gtaaagctca gctaattcgt gattgtttgg
    67081 tttgatcaac aacggtttct taacaagtgc attttttagg tcatcacctg ttgtatcaat
    67141 cacgaaatct gcaccttttt ctcgaatgat atcaatcagt tcttgataaa atccttttcg
    67201 caggctagct ggcgcgcttc ctgacaatac gacgatatct ccttgtccta ctgttcctaa
    67261 tgcttgcttc aactcatcga tttcttcatc tgaaatagat gggcctaagc cattgatctc
    67321 agtttcagtg tctgatttta gtttgatatt gattcttgta tcttctttta cggttgtgaa
    67381 caaagactgg atttgttctt tttcaagcca cttcgaaata aattcgccag tgaaccctcc
    67441 taaaaaccct agtgctgtag attgagaatc gatccgtttc aaaatacggg aaacattgat
    67501 cccttttcct ccaggtaact tgaagtcttc cttcattcgg ttcaaatcgc ctagttttaa
    67561 cccatctacg cgtacgatat aatcaattga tggattaagt gttactgtgt aaatcattgt
    67621 attgcctcct taattgttgt cttttcacgg aattcattaa cgaattctaa tggacaacgc
    67681 tcggttatga tcgtggctgc ttccaaaggt gcaacagagg tgaaggacaa ctggttgaat
    67741 ttggtatgat caatcaatac aaatgtctct tcggaatttt tcatggctaa acgtttaaca
    67801 gctgcctctt ctggatccgg agtcgtgaat ccttgttcaa gatgggcacc gttcattccc
    67861 ataaatgctt tattaaaatg aaaatttttt agttgttcta tcgcattaga tcctaaaaca
    67921 gcattagttg ccagctttat cgttccacct aaaataatgg tagcaagctc caaatcaact
    67981 aaatttgccg catgttgaac ggaatttgtc actactgtga tctgttttcc ttgcagaaaa
    68041 ggaatcattt ctaacgtagt agagccagcg tctaaataaa tgacatcttc gtcattaatg
    68101 gtttcagctg ccgatttggc gatttgctgt ttttcgtgaa cgtttttgag tgatttttca
    68161 ctcatattct gctcaaaatt caataattgc tctttcttag ctccgccatg aactctttct
    68221 agaaacccac tattctccag ctcttgtaaa tcacgtctta tcgttgattc agaagcattc
    68281 aaaaggttta caagatcttg tgatttcacg attttctgct gttcaagcaa gtctaggatt
    68341 ttttgtctgc gttcctctgt aagcattttc acgatcacct caatacaaat aatagcatat
    68401 tttttttcta ctagcaatat aaatcagtca aaaacgttca taaaaattat aaatcagtca
    68461 aaaaaaaata aaaaaccagt cagaaagact ggttttttat ttttttgtct atcatcaagc
    68521 cgttttatcg ttttttattt tcgcttcttg tttttttcat ataaacagaa gcaggttttc
    68581 tttccttatg aagaagataa taataaagtc ccatcccgcc aaacatgacc aaaaaaccga
    68641 tgactgatcg aataggaaaa ttaggaacaa aaaagagaca gacggataat aatgatgccg
    68701 gaaccattat tcgataatag agttgtttat ccattttctt cacctcatat tttttgtaaa
    68761 gtaatcaatt gttctaattc tcggtaatct aaaaattgca cacgcagatg ctgctcacct
    68821 ttcttgacat cgaattggat acttcgccgc tttttcttta ttcgtttgaa ggtaacatca
    68881 gagagtctat gtttgatttc ctttaacggt aattctgaca gggattctga aggaacatag
    68941 attcttaagg ataaaagata ctcttgatat ttttcatctg ttacctctac ttctagatat
    69001 tccctaatat aataacaata agcttcgatt ccattatcca aagcaacagt cggatcgata
    69061 actttatagc acatcatgcg tgatcgattc tcgtcaaccc aaggaaaata cgcctgagca
    69121 tttagtgttc cgcgaacacg cctttcttta taatctcctt gttggatatc ataacttttt
    69181 gttacaaaaa atgaagcatt ctttttagga acaggttgca tttgtgcatt ctgatactgg
    69241 acagattgga tcgtatggtc agtgtaaatg tattcaacga atggcggttt caataaaccg
    69301 acaccattgt cccaagcaag atgatcaaac ccaagctggt ccctaaaata ggattgaaac
    69361 atttgattgt ttggcttttg ccagttaaag gggtctcgat aaagctggat acatatgact
    69421 tcgttttcta attccttcac tttttctact tgttggatgt cgagaaaaat cggtttaggg
    69481 atgatttgat gataatagcg actataatac atttcccaac acgaagtgaa acataaacct
    69541 tggtaaaaaa gatcgtatcc tggaaattgg ttgcaatcga ctactacttc cccgttttgt
    69601 tgtttcattt taggtaaatg ttcgatttca tcctttttct caaacaatag ccgttgagag
    69661 atctgttttg tattgtgata gataaactcg ctataagctc gcatataggc gaacacccca
    69721 tgagcaatca tttttttctg aatgaagtct cgaatcaaaa attgcttttc tttgaaaaca
    69781 gagatagaca atacattttt tatcaataat tgattatctt ccaagcgaaa actacattcg
    69841 ttctcgtcat ttcctacaac taaccaactt tcgtctctta ccgatgctag cattattttt
    69901 tcttgaagct ttcgaagatc atacggatcc gcttgttgtg tgaaagagcg gataaatgtt
    69961 ggctggatca acagacgtgt caaaatagcc caatcgctta tttcctgttt tttttcttct
    70021 tcatttaagt ctgtgagctg gatagtcatc aataatttat cttcgccaat cattttctca
    70081 cctctttcaa atctttttat aatttaatta taaccaatga taaagaaaaa ctaaaacttt
    70141 atgtcttaga aaccaatttg gacgattaca tgatagacta agtaaaaaga aacaaagagg
    70201 tgtttacaat ggggttgaaa tttgaacgta cagataattt agataaactt ttcgaatcat
    70261 ttgctgtcga tccggaaaaa acagttgcac caaaagaaga gatcgatcga tttctaaaac
    70321 cacagccaca aaatgaaaag aaaaaagaca agaaacaaaa gtaagttaag ctcaaaaaaa
    70381 gacttaccag ccaaactttt atgaaagagt ttgactggta agtctttttt attcttttta
    70441 tgattcaatt gcttgttcga ttgctgccca cgcttcttct tttccctgtt ttgtaacgga
    70501 agaaaagaga ataaacgtgt cattgcgatc aaaatccaac gcttttttga tttcgctctc
    70561 atgcttgttc catttaccac gagggatctt atctgcctta gtggcaacaa caattacagg
    70621 gatatcataa tacttcaaaa attgatacat ctggatatct tcttgagaag gcttatgacg
    70681 caaatctact aaagaaacga ccgcacgtag ctggtctcta gtcgttaaat atgtctcgat
    70741 catctttccc cattttgctc gctcagtttt ggatactttt gcatacccat atcccggaac
    70801 atcgacaaaa tgtaatgcgt tctcgatcaa ataaaaattc aatgtctggg tctttcctgg
    70861 cttaccggaa gtacgggcta aattctttcg atcaatcaat gtgttgataa aagaagattt
    70921 ccctacattt gatcgtcctg ccagagctat ttctggcaat tgtgtatctg gatattgttt
    70981 tggtgccact gcacttatga taatttcagc ttgatggact ttcatggtct ctctccttaa
    71041 caaggtgatg aataaagcaa gcggctgtcg caaaagccaa aatgactttt acggcagcct
    71101 cttttcatca acccgctttt ttctctgaat ctttatagat tactgttggc tcaccagaca
    71161 attcagctgc ttcttttgtg ataatcactt tttcgatgtt ttcatttgaa gggatatcaa
    71221 acatcacatc catcatgatt tcttcaatga tggaacgaag tcctcgagca ccggtattgc
    71281 gttcgattgc ttttttcgca atggctctca acgcttcagg ttcgaattca agttcggtat
    71341 tatctagaga aagaagtttt tgatattgtt tgactagcgc atttttcggc tcagtcaaga
    71401 tccgtaccag atcatctgtt gtcaatttct ctaaagctgc cataacaggt aatcgtccga
    71461 taaactcagg gatcaatccg aattttagta aatcttcagg aatgatatgc tgcatgacac
    71521 tttcgtcttc agaaagtttt tggttttgtg taccaaatcc aatcgtcttt tcgcccatac
    71581 gattcttcac aatcgtttcg atgccatcaa atgcaccacc tacgatgaac aatatgttcg
    71641 tcgtatcaat ctgaataaat tcttgatgtg gatgtttacg tccgccctga ggtggcacac
    71701 ttgcaacagt tccttctaga attttcagca aggcttgttg gacaccttcg ccggaaacgt
    71761 cacgagtaat agatacattt tcgcttttac gcgcaatttt atcgatctca tcaatataga
    71821 tgatcccttt ttctgcaagt tccacattgt aatcagcaga ttgaagcaat ttaagcaaaa
    71881 tgttttctac atcttccccc acataaccag cttctgtcaa acttgtcgca tctgcgattg
    71941 caaaaggtac attcaatgtt tttgctaatg tttgtgctaa aaatgtttta ccagaccctg
    72001 taggtccgat caagcagata ttgctttttt gcagttcaac atcatctgtg ttttcttgtg
    72061 cttgctgatt gacacgttta tagtgattgt atacggcaac agctaacgag cgttttgcgc
    72121 gatcttgtcc aatcacgtag ttattcaata cttcaagaat ttctagtggt ttagggactt
    72181 cagtgaattc gcgtacagct tcttcataaa attcttcatc aatgatttct ttacataggt
    72241 cgatacattc attacagatg tagacccctg gaccagctac gatctttttc acttcttctt
    72301 gggttttccc gcaaaaagaa cagcgtacgg tctcattgct acttggattg tcatacatgg
    72361 tcttcacccc ttaacttgca aaaagtatgc aagaaactat caaagacttt acagtctttt
    72421 actatcataa catagtttag taaaaagaaa aagtgtttaa caaaggatca actgacctat
    72481 acctttgcat tttttactct taacaaaaaa taaggaactg tgacaaaatc gtgtcacagt
    72541 cccttatttc gaataaacaa ttttctagaa gtagcttctt cagaaatgat ttattacttg
    72601 atttctattc tttcgcttct gtcgctgtac ctgtgatcaa ttcgattgct tttttcattg
    72661 tcacatcatg ttccagcata tcttctgtca acacgcgttt gatttgttcg attggcatgt
    72721 tgtatgtttc tgataattct tggatttctg cattgatttc ttcttctgtt gcttgaagat
    72781 tttcagcagc tgcaattgct tcgatcacaa gatttgttct tgtgcgcatt tctgcttcac
    72841 cttcgaattg tttatgcaag tcttcttctg tagaaccagt taattgatag tacatttcag
    72901 gagagatacc ttgacgttgc atgttgttca agaattcgtc cattgaacga tgtacttcat
    72961 catgaaccat cacgtgtggc aattcaacga tttctgcgtt ttcaacagcc atacggatcg
    73021 ctgcttcatc ttttgcatcg tccgctgctt tttcttttgt ttctactaat tctttgcgat
    73081 atttttcttt caattcgtct aatgttgata cttcgtcatc aacatctttt gcgaattcgt
    73141 catctaattc aggcacttct tttgctttta cttcatggat tgtcactttg aagactgctt
    73201 cttttccagc aagatcttct gcttgataat cttctgggaa agttacattt acatctagac
    73261 tttcacctga tttatgacca actaattgat cttcaaaacc tggaatgaat gagcctgaac
    73321 ctaattcaag tgagtaattt tcgccttttc cgccatcaaa cgcttcgcca tctacaaagc
    73381 cttcgaagtc gattactact gtatcgccat tttcagctgc agcatcttct ttgataacta
    73441 attcagcttg tgcttcttgt tcacgtttga tacgtgcatc cacgtcagca tctgttactt
    73501 cacggtcttg tttttcaaca actagatctt tatattgtcc taattttact tctggtttca
    73561 ctgttacttc agcagtgatt acccagtctt gacctttttc catgctttca acatcgattt
    73621 ttggttgaga aacaggatcg atgccagctt ctttgacagc agcttcataa gcttctggta
    73681 atacagcatt caatgcatct tcatataaag cttcttcacc gtacatacgg ttgaatactt
    73741 gacgagaaac tttcccttta cggaatccag gtacgttcaa gctttttttc actttattaa
    73801 acgcagttgt taatcctttt tggatttcgt cttgcgcaat cgtaaatttt aaaacaccat
    73861 cattcgtgcc ttttttttca aatgttgcag tcatttaatt ccctccgagt ttagaaattc
    73921 attttataca tcaaaaacgt ttcatgcata cctttaaata gtacactaac cctttcaaat
    73981 tgtaaacata ttgaatggat agaatccttg tttttcataa catttttatc tttttcactg
    74041 ataaaatcta atggaagaag atcatttgct gcaaaatttt ttctcttttt tttaaaaaat
    74101 cttgtttttc atcttctgta ccttcataca tcgtttttcc tgtacacgcc tctacagtca
    74161 gttgaaacca gcgcttcggg tcttcgatgt atgtatcata gacaggataa acaattgcag
    74221 attgcaacgt gaattcttct tttaacacgg aactaagcag cgcatcttca ttcccgtaac
    74281 gatctgaaaa tacacataat tgctggtaac ttgcctgctg ctgcggcttt ggcagatctt
    74341 ttggtatgac tttgactaac ttttcttcaa tcgtcaaata gaaaacttga tggcattcgt
    74401 tcaattgcct aagtgtctcc agtaattttg cccttgctaa aatatggacc tctggcgata
    74461 caataagttt actcgctgtt tggataaact catgataagg aagctgttcg atctcatcaa
    74521 tagacgcaag ctgacgtgca ggttccaacg aaggaagttc ctccgattta ttgtggagtg
    74581 ccttgatctt ctgcctctcc atttgtccgg ataattcttc tgcaaattgg attttttcaa
    74641 tgacccgctg ctcgaaagct tcataaaaat ctgtacttgc tatcaatttt ctagcatata
    74701 aaaaatcttg tgtactgatt aacaagtcaa aataaaattc agcaaactcc tcattttgaa
    74761 gatactgttt ttcatgcaag agtgcttgct tcaatgcttc ttttttctcg tccaactcgt
    74821 aaagacaaaa aacaagcagg ctattagcct caaagctttc tttcaactcg taagctcgtt
    74881 gaaataattc ttttgcctgc tgatattgct ggtttgctag tgcttgttgt gccactcgca
    74941 ttaaattctc atatttttct ggaaaatcaa tcggcttcac gcagtgtcct cctcttgctc
    75001 atattcagct catgttcaat agtagcaaaa caaaaaaagc atgacaatta aaaataactg
    75061 aagcaccctc taaaagctag attttagatc tgacttttag aaggtgcttt caactgttac
    75121 tgctttttat tgctcatcag ctgttgactt cctggttgaa cgctttgatc agattgatcg
    75181 taacaacact tgtattagtg aaaaaatcgc ccagatgttg ctttttctga ttaaagactg
    75241 ctggaagata ccctaacatc agcaaaggaa attttagaat gaaccggcaa gcaccttctc
    75301 taactaaaac ggttgaccag ctaagttctt cttcatcaaa gctgatgact cgaataccaa
    75361 agatcatttt cccaatcgtt tggccatgat tgaatttcgt caataaaata aaatacgcta
    75421 gataaataag taaggctgtg aatccgtaga gactcagata agaatctgaa aaattaagcc
    75481 aacctagatt tttggcaata ccaagtgtta aacgcgtaat agctccgata cacaaaagat
    75541 cgaccaagaa ggcaaacatt cggataaaaa aacctgcata gaaatactta ggaaaatcat
    75601 ttgcttttgg cggttcattt cttgtgtccg tatacttttt ccatttacgt tgtttctttt
    75661 tgatttcttc gggcgtcaaa ggctctcttt caaaagagct cagtaccttt tgggaaaagt
    75721 tggagtcagg tcctacagca ggctgctgtt gcttatcttt ttcttgttcc ttattttcat
    75781 ttgaaagctc tgacatgctt actcacctcc gtaataatac attgcttttg gtgattccgc
    75841 tgtccctaga ttctcaagaa cggataagat ctgactagtc tcagaaggct tcaatccctg
    75901 gaattctgct agtttacttc ctaaccatgt actagcaaac ccagatggcg tggaagaata
    75961 ttctactagt tccgcatctt caagctgttg ttcctttcgt atagctttta aagcatcttc
    76021 aggaaatccc aattcatcga ctaaacctac ttcttttgct tggacaccat cataaatcct
    76081 tccatcagca atttttttga cttcttcttc agatttattc cgtccctcgc tgacgattgc
    76141 tacaaaacga ctatatgcgc tgtcgatata tgcttgaagc accgcttctt cttcttttgt
    76201 ctctggtcgc gttcctgaac ccatatcttt caacgctccg cttttaactg ttgtatcttc
    76261 cacacccagt ttttctagaa gtcctgaata attcaatcct gacatgatca caccaattga
    76321 gccggtcact gtttcttctg ttgcaaagat tttatctgct tgagcagaaa tatagtagcc
    76381 accgctagct gccatgtttt tcatgctgac atacattggg atatcatgtt ctttacgaat
    76441 cgtatccaat ttcttagcga tttccgcact ttcgtagaca ccgccaccag gagaatttac
    76501 ttctaaaaag atacctttga ctgttggatc ttcttcaatc gccttcagtt gttccataaa
    76561 atttttatga ttgtaacctt cagaagcaaa taaacctgaa gaccctcccg cagcaatcgt
    76621 tccatctact gataatttta cgattttttg cgtactgtct ccctcttcca acacatttgg
    76681 agctagttct tcatccccat ataaccaact gttcaatccc tcaatttgat cgttttcctg
    76741 aggcttagtc aaactagctg aaactaacga aaccacaaat aatcctgcag caatcagaac
    76801 tgctgcccaa cgtcttttat tcattctttc tcctttctaa tacaagtttt ttatgacgat
    76861 cacagtttct gactgctcag aagtgtcgaa ccgctctgct ttttcttccc gcgcataccc
    76921 ggaaaacgac tcttttgtta attcatcttc taccgtaaac tcacgagctt gagcaacttc
    76981 caaggcatca ggtgcgattt cttggatgct atcccagcca gtatctaaaa atattttcgt
    77041 atcatctgat acaccagctg atgcttcgaa tttggacaat tgttttttta acattcccag
    77101 tgtcatgatc tcaatttttg aatccatttt tactcctcct ctatccgatt actttctatt
    77161 gtaccgaact cctgaaaaag atgatagata aaaacccatt attttttgac ataaaaagga
    77221 catttgacaa agaatttgat atataccaat ttatttttta ttcttttttt gttgacaaga
    77281 acattcgcaa aaggttatga ttttaaatgt ttccagataa aaaacaaaaa ggaggatagt
    77341 tatacctttt aggatagcgc caggtctgtg taaacagatg acgaggagag ggtttatcga
    77401 aagattcggc ggatggccct agggactgca ctctacagaa aatccacaaa aaatgtctgc
    77461 aaagataaaa caaaaggatt ttcctgcagc tggaagcatt catacgaatt cattatagaa
    77521 agtaggatgt tttttatgtg cggaattgtt ggaatgattg gattaaaaaa tgtaacacca
    77581 ggattgattg acggtctaga aaaattagaa taccgtggtt atgattcagc tggtatcttt
    77641 gtctcagatg gcacaactga ttatctggtc aaagcacaag gcagaattca aaatttgaaa
    77701 aacaaaataa atattgatac tacaggaaat ataggtattg gtcatacacg atgggcaact
    77761 cacgggcaac cttctgaaga aaacgcccat ccacatactt cccaaagtgg acgcttcgtg
    77821 ctcgttcaca acggcgtaat cgaaaacttt gaagaactta aaattgctta tttagcaaat
    77881 gaccacttta ttggtgagac cgatactgag attatcgctc atctaattga aactttcgcg
    77941 aaggatacta caacgcaaga ggcgttttta aaagctttgc gggtcatcaa aggttcttac
    78001 gctttcgctt tgattgatcg gacagcacct gatgttattt acgtcgctaa aaataaaagt
    78061 ccactattaa tcggactcgg cgatggattc aatgtgattg ccagcgatgc aatggctatg
    78121 cttgctcata cgaaggaatt cgttgagatt gaagatgaag agatggttac cgtcacatca
    78181 gaaaaagtta ttattcaaaa ttttgcaggt gacatcgtag aacgttcttc attcgaagca
    78241 caagtagatg cttcagatat cgagaaaggt acctatcctt tttatatgct gaaagaaatc
    78301 gacgaacagc ctattatcat gcgtcgtatc gctcaaaaat acgtaacaga agacaatcgt
    78361 gtctctcttg atcaaaagct ggtcgataca ttgtctgata gcgatcgaat ctatatcgtt
    78421 gcttgcggaa ctagttacca tgcggggtta gcaggtaaac agactttgga aaaattgaca
    78481 cagattcctg ttgaggttca tttagccagt gaatttggct ataacacacc tcttctttca
    78541 aaaaaaccat tctttatttt cttgagtcaa agtggcgaaa cagcagacag ccgccaagtg
    78601 ctggtaaaaa tcaaccgtct cggctaccct tcacttacga ttacaaatgt tgctggttct
    78661 actctttcgc gggaagcatc ctttacactg ctattgcatg ctggacccga aatcgcagta
    78721 gcatcaacga aagcttatac tgcacaaata gctgtactaa ctttattagc caaagctatc
    78781 ggtgataaaa aagaatttga aacttctctt gtattcgata tcactcatga attgagttta
    78841 gttgctaatg cgatggaatc ggtcatcgcc caaaaagatt atttagaaga gttggcagaa
    78901 gtatatctca gcgatacaag aaatgccttt tacattggac gtggtgctga ctacaacgtt
    78961 tctcttgaag ctgctttgaa attgaaagaa atcagttata tccaggcaga aggttttgcc
    79021 gctggcgaat tgaaacatgg aacgattgct ttgatcgaag aaggaacacc agtgatcgga
    79081 atcatcagtg aagaagtgac tggtgcgcat actcgaggaa acctgaaaga agtcgaaagc
    79141 cgtggcgcta aaacactagt tattgtctca gagggattag aaaaggaaag tgaccagctg
    79201 gtgctaccaa ctgtccaccc ttatctaact actctaacca cagtcgtacc gactcaatta
    79261 cttgcatatt acgcaacgct attacgggga ttcgacgttg acaaaccacg taatttagcg
    79321 aaatcagtga cagtagaata ataaaagaac aaggaccagt gtcagacatc tgacactggt
    79381 ccttgttctt ttatttttta tgaaaatatc tcttaatcca gtccgatttc ttctttgact
    79441 actgccgcga ttttatcgac atagtaatta actttctcat cagtaggcgc ttctgccatc
    79501 actcgaagta atggttctgt accggaagga cgaactagga ttcttccttc tgatcccatt
    79561 tcagcttctg cctcttcaat cacttttttg attgccggaa catccatcgc accgttttta
    79621 tcacttacgc ggatattcac taatttttgc ggatagattg ttacctctgc tgcaagctct
    79681 gataatttct tacctgtctg tttcatgata ttcagtaact gaattcctga aagcatccca
    79741 tctccagttg tgttaaaatc taagaaaatc atgtgcccag actgctcgcc gccaaagtta
    79801 taatcgtttt tgcgcatttc ttctacaacg taacgatcac caacttgtgt aacgacatct
    79861 ttcaaaccga ttccttccac cgctttgtgg aatcctaagt tactcatgac agtcgtaacg
    79921 atcgtatctt ttttcaatcg atttttttct gccaagtatt tagcacagat aaacatgatt
    79981 ttatcaccgt cgacaatgtt tccaagttca tccaccgcaa taatacgatc gccatcgcca
    80041 tcgaaagcta gtccagcatc tgctcctttt tcaacgacca tctcagctaa acgttctgga
    80101 tgggtagagc ctacgccgtc attgatattt aacccgtctg gatttgtgcc cattgtataa
    80161 aaatctgttt caagatcggc aaacaaacga ttaacacttg ttgaagttgc tccgtttgct
    80221 gcatcgacac aaatggtcaa accggaaagg tcaccgttga tcgtttgtac aaggaattga
    80281 gaatatttca ataagccttc tggaaattct tctacagttc ccaatccttc agctgatgga
    80341 cgaggcaatt catccacttc agcatctaat aatgcttcaa tttctagctc ttggtcatct
    80401 actagtttaa aaccatctgc accgaaaaat ttgattccat tatcttgtgc tggattatga
    80461 gaagcagaaa tcatgacccc tgcgcttgct ttttgcaaac gtgtcagata agcaacacct
    80521 ggtgtagaga tcacacctag ctggaacact tcgataccca ccgataaaag tcctgaaatc
    80581 agcgcttctt ctaacatttg acctgagatt cttgtatccc gccctactaa cacgcgtggg
    80641 cgttttcctt cttcttcatg ctggcttagg acataacctc cgcaccgtcc cagcttaaat
    80701 gcaagttctg gcgtaagttc cttgttggct tcaccgcgta cgccgtctgt tccaaaatat
    80761 ttacccatag ttgtaaaatt actcctttaa cttaattttc tgaggaattt gttctgctca
    80821 tttgtgttga ttcgcttgtt tctgatgttt cttctgtact tgtggtcgag ctgcttgtcc
    80881 cagattccga actggaagaa atggttgttg tcgatggttc cgttcctgaa tcagcagatg
    80941 aaatacttct actcgtactt gtattttctt gtgtccgact gctcgtcgaa gcagagctac
    81001 tgcttgacgt ttgcaacacg ggtgtaatct ccacactaac tgattcgggc ttgatactta
    81061 acccctcttc tactggtatt tcaattttac gagttgttcg atgattgata cctgagacat
    81121 tgatcggtac agcaatactg tcaccgatcg atgcaagcaa atcgctagag ccgcttactt
    81181 ctgcttccag ttttgaaaaa ctgaaatcat agctttctac cccggcagct ggtgttcctt
    81241 gctgtatccc ataaagtcgt accgacttgc ttggcttgat cgaatcagct ctcactgtta
    81301 cttgcactgg atcagagacg atacttaata cttcccctgc tgcattcagc gcctgtattg
    81361 ggacctcact attaatccca tcatctgtga ccatcgaagc gtccacatca gctactactc
    81421 gtttgatttc tgccaatgtt ttgtcacctg tagtgataga gactttttta ggactaacgg
    81481 aagtatcatc aagttcatat ccagatggtg tgaacgttga aggaatcaac gtttccacat
    81541 cgaaatcttt tattaccttt ttctcaaccg ttactgtaat agtcgatggt tcgatctttg
    81601 ctgtgacagc actgctcaaa ttttgaattt ttagcggaac ttcatgtgtt ccttcgccca
    81661 gcttagtgat atctgctgtg acgcggaaca tccgtgtatc ttcgtttgcc tctgcattca
    81721 actgaactcg gtttgcactg gaaagtttga cagtcactgc attttcatat ccatggatat
    81781 agtagcgctt tgaatcataa gaaatcttga tcggcacccc cgtaactgtt tgattatacg
    81841 cttcatttcc agaaagcgta tttggaacgg actggccatt tgcattgaag tacagcgcaa
    81901 tactgaacag caatgcaata aaactgtaaa gaatgcttgt ccgtttctct tttgagatca
    81961 tttgcgatcc cctcccttag tcataccgtc taggaaagat tgaatcacgt ttttcttgtt
    82021 ttttgttttc tcttcagcaa ttagttctct acgcaagatt gccaaatatt cttgctggga
    82081 taagccagcc atcagttcat tatctaacgt gatgctgacg tccccggttt cttcagagac
    82141 aacgatggta atcgcgtcac tgacttcgct tataccgaca gctgcccggt gtcgagtccc
    82201 gaattcttta gggatcaaca tactttctga tagaggaaga taggcgcttg ctactgcgat
    82261 ctttccttct tttacaataa ctgcaccgtc atgcagcggt gtattaggaa taaagatatt
    82321 gatcagcagc tccccagtga tatctgcatc taaagcaatc cctgtctcaa tatactcatc
    82381 taatccagta tgacgttcga tagtgatcaa cgcaccgatt tttcgcttgg acatatattg
    82441 gatggctttg tcaaaagaca agatcatctt ctcatcttcc tgctgttcgc tttttgattg
    82501 tttgaaaagc gaactgcgtc caagatgttc cagtcctctc cggatttccg gctgaaaaat
    82561 cacgatagca gctatcaccc cgtacgtaat gacttggttc atcagccaag acaaggtgtg
    82621 cagaccaatg atttccgcta cgattcggat aacaataaaa atagctacac ctttcagaag
    82681 ctgaatcgct tttgtgcctc gcagcagttg gatcagtttg tatacaagat accagacaac
    82741 cagaatatca agtatgttca ccaaaaaatt cagagagaac aagtcaccgg aaaacatttg
    82801 ctgccaatag tccaaattaa aaagttcccc gatttgaaat gacataaaaa gcctctcttc
    82861 tcttttgaga tttcctctct agtatatcat atgttttaat tttagaggct gatatgctcg
    82921 tatttttctt gagaaaaacg cataattttc aagaaaattg caagtatgcg ttttattttt
    82981 ctctgcaata aatattttta aacttcagag aattattcat tatatttttt ctgttatttt
    83041 tccttttttt cttttgtagc ttgttccatt tttttacgtc gttctgctct ggcagctctt
    83101 ctagcagctc ttctttcttc tgcttcaagg tccgtcgttt tttcttttct agtcttaacg
    83161 ggtacatcga tagattcctc tggttcaagt cgtttcttga ttttttctaa ttctcccgtc
    83221 agtgcagcat agttgtaaaa acgtgtttta gcgtcgtgga cagtcttttc aaataaagct
    83281 tttgcaagat ttggatttgc gttatctagc gaggaaaagc gaacttgttt cctcatgaaa
    83341 tcaggcatag cagagaaatc aggttttttg tagtccaaag tcattgggtt cttgtttttt
    83401 tcgaccattg tagggttata tcgatataat gaccaataac cagaagaaac agcttctttt
    83461 gcttctttaa gcgattcttt cattccgcca agcaagccat gtgtgataca aggcgtatag
    83521 gcaataatca gagaaggacc aggatacttt tctgcttctt caaatgcctt gatcgtttgc
    83581 atttgattgg cacctgaagc aatttgcgcc acataaacat ttccatatgt catcgccatc
    83641 attcctagat ctttctttga agcatacttt ccactagccg aaaatttagc gattgccgaa
    83701 gctggtgttg cttttgaggt ttgaccgcca gtattggaat agacttcgtt atccaaaaca
    83761 aggatattca cgtctgctcc gctggcaagt acatgatcga tcccgccaaa accaatgtcg
    83821 taagcccatc cgtctccacc aatcatccat tggctgtttt ttacgaatag atcctttctc
    83881 ttgtatatat cctccagttc agggaaaatt gatcgttcgc tttcgatcgc agcttgcagt
    83941 tttgctgctc tttgctgcgt tccttcactc tcaaacatgt gtactaacca gtcttccatc
    84001 aattctcgta gttcttctga tacttttggc aatacttctt tgattgaact tgccaaagcc
    84061 tcgcgacgag tctgtgccgc tagaagcata ccataaccaa attcagcatt atcttccaat
    84121 aaagaatttg accatgcagg cccttgacca cattcattgg tcgtataagg agaagcagga
    84181 gaagcaccgc cccaaataga agaacagcct gtcgcattcg cgatcatcat tcgatcaccg
    84241 aacatttgtg tcaataattt tacataaggt gtttcgccac agcctgagca agcgcccgag
    84301 aattcaagaa gcggttgatt gaattgtgta gacaagacag tattctttcc tttgactgga
    84361 tttgcttttt gtcttaatgt cattgcaaaa gcccaattca cagcttgttc tttctgttct
    84421 tcataaggct tcatcactaa agctttttct tttgcgggac aagcctctac acacagacca
    84481 caacctgtac agtcttccac tgaaacttgg atacggtatt ttacgccgtc tgcgcctcgc
    84541 atttctctca cgataaatcc ttctggcgct tcttccattt cctcttcatc tgctaaaaat
    84601 ggacggatgg cagcatgagg acaaacaaag gcacattcat tacacatcgt acagcgatca
    84661 ctaatccact caggtacttc taaagcgacg ccccgctttt ccatagaagc cgttcctaaa
    84721 ggcatttcgc cagttgtcat tccatttgct acaagtgtac caacagagag ttgatttcct
    84781 tcctgtgcat tcactggttc aagtatttct tgtatataac cagtgttcct tttattgatt
    84841 ttttcaggca tctccaacgt tctccaatgg tctgggatcg cgacttgatg aagcagttcg
    84901 gtcgtccgat cgattgcttg tatgtttttt tctacgatag ccattgattt atgtccatag
    84961 cttttcaggg cttcttcttt tagcagcgga agcacctcat caaaaggaat gatgtcagct
    85021 aatttaaaaa aagccgtttc cattgccgta ttgatccggc gtcccaaacc gacttcttgg
    85081 gccaatctca tggcattgat cgtatagaat ctaatgttat tttcagccaa gtaacgtttt
    85141 aattttaagg gcagatgcgt ttctaattgt tcgtcgctcc aaagagtatt caataaaaaa
    85201 atgccacctg gcttcaatcc tttgaccaag tcatagctat gcaggtaagc tggtgtgtga
    85261 caggcaacaa ggtccgcatg ctcgacaaga tacgctgaac gtatcggcgt atctccaaaa
    85321 cgaagatgag agacagtcag accgccagat tttttcgaat cataataaaa atagccttgc
    85381 gcatatttat cggtgtgatc tccaataatc ttgatagctg atttatttgc tccaactgtt
    85441 ccgtcagatc caaatcccca aaacttggcc tggaatgttt gcggttctgt caaatccaga
    85501 ctttcctttg gttccaaaga ttgataagtc acatcatcca cgatccctat ggtaaaccgt
    85561 tttttgcgta tgcttgggtc ttttttcaat tcatcaaaaa ctgctgagat ttggtcggga
    85621 gtcacatctt tagaccccaa tccgtagcga ccaccaataa cagccgggcg aagttcagaa
    85681 tcatataacg cactttgaac gtctaataag agaggttctc cacctgcccc tggttcttta
    85741 cttcgatcaa gaacagcaat tgtttttact gtatgaggca acttttgcac gaatgtttcc
    85801 actggaaaag gacgataaag atggatattc aaaaaacctg ttttccgtcc gtttgcattc
    85861 aagtaatcaa tcgtttgttc aatcgtctgt gcaactgatc ccatagaaac aatgacttct
    85921 tccgcatcgt ctgctccgta ataagtcacc aagtcataag aagttcctcg taatcggttg
    85981 atctctttca tatatttttg aacgatttca ggtaatttat cataataggg gttgatcgtt
    86041 tcccgttgtt gaaaatggat gtctggattc tggttcgtac cactaacagt cggatgattg
    86101 ggattcatcc ctcgtttacg aaatgaagct aatttctcct gattgatcag aggagctaat
    86161 tcttcatatt ccaaaacttc gattttttga atctcgtgac tcgtacggaa tccatcaaag
    86221 aaattcaaaa aagggacttc tccttcaata gaagcaagat gggcaacagg tgctaaatcc
    86281 atcacttctt gtacactgct ttcagctaac atagcaaatc ctgtttgtct tgcagccatc
    86341 acgtctccgt gatctccgaa aatattcaac gcatttgtcg tcactgcccg actagcaacg
    86401 tggaaaacac ttggcagtag ttccccagca atcttgtaca tattcggtat catcaaaagc
    86461 agcccttgtg aagcggtata tgtagttgtc agtgcaccag ttttcaatga tccatggacc
    86521 acaccagctg ctcctgcttc ggattgcatt tctactactt ttactggttg accgaatacg
    86581 ttttcttttc ctgctgctga ccattgatct actaattcag ccatggtcga actgggtgtt
    86641 attggatata ttgcagcaat ctcggtaaat gcataagaaa tatatgcggc tgccgtattg
    86701 ccatccattg ttttcatttt tcgcatgatt catcatcctt gttcatattc tctcttatta
    86761 tctgttccat tataacgtaa aacatgccat ttttttcttt tatttataaa aatattttac
    86821 atgtatctat ttgaattggt catctaattt ttagacaaac agtctaaatc gttgcctttt
    86881 tttgtcagac atgtataaac tataagcgaa agaggtgttt taacatggat atatcagtga
    86941 ttgatgcaac gaaaacaaat acacaaaaag gaatccttta tggttcatcg aatgctccta
    87001 aaaaaatggt cgaattcatc aacttagctt gtccgtattg ccgacaatgg tttgaagaat
    87061 cttatgagct attagaagaa gcagtccaaa gcgggcaatt gcagcgagtg atcaaattgt
    87121 tcgataaaga aaaagaaagc ttacagcgag ggaacgtgat gcaccggtat ctcacaatca
    87181 gcgatggcca aaaagcgatc aaagagatca aacaaatatt cgatactcaa gacgagtgga
    87241 aacatctttc tctccaagaa gtagcggatt ttgcagtaga taaactaaag ctgacagaac
    87301 aaaaagacga acagctgagc caagctgtca tcaacgaagc tgagcaagca catattcgat
    87361 ttgttccaac tgtcatcttg ggtaaagaaa tctttgatga atctatttca atagaggaat
    87421 taaaagaatt gatccaaaca aaataaaaaa ataaggagcg tg
//
LOCUS       DAZKPE010000003        87294 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000003 DAZKPE010000000
VERSION     DAZKPE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.003"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACG930_000181"
     CDS             476..1339
                     /locus_tag="ACG930_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0517377.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACG930_000182"
     CDS             complement(1468..3090)
                     /locus_tag="ACG930_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0517378.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACG930_000183"
     CDS             3339..3860
                     /locus_tag="ACG930_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFQ0517379.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG930_000184"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG930_000184"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFQ0517380.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACG930_000185"
     CDS             5941..6759
                     /locus_tag="ACG930_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFQ0517381.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACG930_000186"
     CDS             complement(6862..7059)
                     /locus_tag="ACG930_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517382.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACG930_000187"
     CDS             7228..7806
                     /locus_tag="ACG930_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFQ0517383.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACG930_000188"
     CDS             7901..8038
                     /locus_tag="ACG930_000188"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517384.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="ACG930_000189"
     CDS             complement(8851..9354)
                     /locus_tag="ACG930_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0517385.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="ACG930_000190"
     CDS             9713..10738
                     /locus_tag="ACG930_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0517386.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="ACG930_000191"
     CDS             11061..11939
                     /locus_tag="ACG930_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFQ0517387.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="ACG930_000192"
     CDS             12415..12531
                     /locus_tag="ACG930_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFQ0517388.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="ACG930_000193"
     CDS             13459..13797
                     /locus_tag="ACG930_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517389.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="ACG930_000194"
     CDS             13891..14121
                     /locus_tag="ACG930_000194"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFQ0517390.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="ACG930_000195"
     CDS             14521..14892
                     /locus_tag="ACG930_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFQ0517391.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="ACG930_000196"
     CDS             complement(15166..15858)
                     /locus_tag="ACG930_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0517392.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="ACG930_000197"
     CDS             complement(15861..16646)
                     /locus_tag="ACG930_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0517393.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="ACG930_000198"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="ACG930_000198"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFQ0517394.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="ACG930_000199"
     CDS             18308..18625
                     /locus_tag="ACG930_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0517395.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="ACG930_000200"
     CDS             18638..20311
                     /locus_tag="ACG930_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFQ0517396.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="ACG930_000201"
     CDS             20325..21956
                     /locus_tag="ACG930_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFQ0517397.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACG930_000202"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACG930_000202"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFQ0517398.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACG930_000203"
     CDS             complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACG930_000203"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFQ0517399.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="ACG930_000204"
     CDS             25190..25795
                     /locus_tag="ACG930_000204"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0517400.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="ACG930_000205"
     CDS             26103..27119
                     /locus_tag="ACG930_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0517401.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="ACG930_000206"
     CDS             27260..28561
                     /locus_tag="ACG930_000206"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFQ0517402.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="ACG930_000207"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="ACG930_000207"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFQ0517403.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="ACG930_000208"
     CDS             29290..29688
                     /locus_tag="ACG930_000208"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFQ0517404.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="ACG930_000209"
     CDS             29754..30836
                     /locus_tag="ACG930_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0517405.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="ACG930_000210"
     CDS             31048..32610
                     /locus_tag="ACG930_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517406.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="ACG930_000211"
     CDS             32603..33736
                     /locus_tag="ACG930_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517407.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="ACG930_000212"
     CDS             33736..34692
                     /locus_tag="ACG930_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517408.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="ACG930_000213"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="ACG930_000213"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFQ0517409.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="ACG930_000214"
     CDS             35981..36799
                     /locus_tag="ACG930_000214"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFQ0517410.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="ACG930_000215"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="ACG930_000215"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFQ0517411.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="ACG930_000216"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="ACG930_000216"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFQ0517412.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="ACG930_000217"
     CDS             complement(38679..39260)
                     /locus_tag="ACG930_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0517413.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="ACG930_000218"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="ACG930_000218"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFQ0517414.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="ACG930_000219"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="ACG930_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFQ0517415.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="ACG930_000220"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="ACG930_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFQ0517416.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="ACG930_000221"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="ACG930_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFQ0517417.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="ACG930_000222"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="ACG930_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFQ0517418.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="ACG930_000223"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="ACG930_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFQ0517419.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="ACG930_000224"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="ACG930_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFQ0517420.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="ACG930_000225"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="ACG930_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFQ0517421.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="ACG930_000226"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="ACG930_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFQ0517422.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="ACG930_000227"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="ACG930_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFQ0517423.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="ACG930_000228"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="ACG930_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFQ0517424.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="ACG930_000229"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="ACG930_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFQ0517425.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="ACG930_000230"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="ACG930_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFQ0517426.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="ACG930_000231"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="ACG930_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFQ0517427.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="ACG930_000232"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="ACG930_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFQ0517428.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="ACG930_000233"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="ACG930_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFQ0517429.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="ACG930_000234"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="ACG930_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFQ0517430.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="ACG930_000235"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="ACG930_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFQ0517431.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="ACG930_000236"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="ACG930_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFQ0517432.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="ACG930_000237"
     CDS             51714..51899
                     /locus_tag="ACG930_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFQ0517433.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="ACG930_000238"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="ACG930_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFQ0517434.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="ACG930_000239"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="ACG930_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFQ0517435.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="ACG930_000240"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="ACG930_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFQ0517436.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="ACG930_000241"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="ACG930_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFQ0517437.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="ACG930_000242"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="ACG930_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFQ0517438.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="ACG930_000243"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="ACG930_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFQ0517439.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="ACG930_000244"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="ACG930_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFQ0517440.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="ACG930_000245"
     CDS             55974..56621
                     /locus_tag="ACG930_000245"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFQ0517441.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="ACG930_000246"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="ACG930_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFQ0517442.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="ACG930_000247"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="ACG930_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFQ0517443.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="ACG930_000248"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="ACG930_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFQ0517444.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="ACG930_000249"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="ACG930_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFQ0517445.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="ACG930_000250"
     CDS             58059..58997
                     /locus_tag="ACG930_000250"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFQ0517446.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="ACG930_000251"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="ACG930_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFQ0517447.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="ACG930_000252"
     CDS             59677..60516
                     /locus_tag="ACG930_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0517448.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="ACG930_000253"
     CDS             60492..61361
                     /locus_tag="ACG930_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0517449.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="ACG930_000254"
     CDS             61351..62148
                     /locus_tag="ACG930_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFQ0517450.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="ACG930_000255"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="ACG930_000255"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFQ0517451.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(63430..66099)
                     /locus_tag="ACG930_000256"
     CDS             complement(63430..66099)
                     /locus_tag="ACG930_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFQ0517452.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(66337..66525)
                     /gene="rpmB"
                     /locus_tag="ACG930_000257"
     CDS             complement(66337..66525)
                     /gene="rpmB"
                     /locus_tag="ACG930_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFQ0517453.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            66795..67157
                     /locus_tag="ACG930_000258"
     CDS             66795..67157
                     /locus_tag="ACG930_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0517454.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            67209..68891
                     /locus_tag="ACG930_000259"
     CDS             67209..68891
                     /locus_tag="ACG930_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFQ0517455.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            69008..71044
                     /gene="recG"
                     /locus_tag="ACG930_000260"
     CDS             69008..71044
                     /gene="recG"
                     /locus_tag="ACG930_000260"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFQ0517456.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDERPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            71093..72094
                     /gene="plsX"
                     /locus_tag="ACG930_000261"
     CDS             71093..72094
                     /gene="plsX"
                     /locus_tag="ACG930_000261"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFQ0517457.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            72216..72458
                     /gene="acpP"
                     /locus_tag="ACG930_000262"
     CDS             72216..72458
                     /gene="acpP"
                     /locus_tag="ACG930_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFQ0517458.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            72726..73730
                     /locus_tag="ACG930_000263"
     CDS             72726..73730
                     /locus_tag="ACG930_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517459.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            73731..74675
                     /locus_tag="ACG930_000264"
     CDS             73731..74675
                     /locus_tag="ACG930_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517460.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            74675..75637
                     /gene="opp4B"
                     /locus_tag="ACG930_000265"
     CDS             74675..75637
                     /gene="opp4B"
                     /locus_tag="ACG930_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFQ0517461.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            75664..76578
                     /locus_tag="ACG930_000266"
     CDS             75664..76578
                     /locus_tag="ACG930_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517462.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            76604..78385
                     /locus_tag="ACG930_000267"
     CDS             76604..78385
                     /locus_tag="ACG930_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0517463.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            78733..79419
                     /gene="rnc"
                     /locus_tag="ACG930_000268"
     CDS             78733..79419
                     /gene="rnc"
                     /locus_tag="ACG930_000268"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFQ0517464.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            79439..83020
                     /gene="smc"
                     /locus_tag="ACG930_000269"
     CDS             79439..83020
                     /gene="smc"
                     /locus_tag="ACG930_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFQ0517465.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            83029..83838
                     /locus_tag="ACG930_000270"
     CDS             83029..83838
                     /locus_tag="ACG930_000270"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0517466.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            83849..84847
                     /gene="ftsY"
                     /locus_tag="ACG930_000271"
     CDS             83849..84847
                     /gene="ftsY"
                     /locus_tag="ACG930_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFQ0517467.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            85034..>87294
                     /gene="gshAB"
                     /locus_tag="ACG930_000272"
     CDS             85034..>87294
                     /gene="gshAB"
                     /locus_tag="ACG930_000272"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFQ0517468.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEV"
BASE COUNT        28173 a        15651 c        18682 g        24788 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgtc ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggaa
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga tttattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg cagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttaa gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcaagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat agaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcgtac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgatcggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt acccacttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa aatacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacaccc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttatgatag aagtggtcag
    63121 cttcaagaaa taagaaggta tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga agaagctact tctggaacac cgtttaagaa agaggtcgtg agcctgtcat
    63241 ttaactctga gtcacaaaga gcaatttcaa aaaacagctt ctcatctttg atgaatatcg
    63301 tgacttgtgg acgaggcgtt gataagtgaa tcatcttttt gttacctatt ttttctgtaa
    63361 ccaaaaaacg atggaacgtt gttttgattg cccttggtgc ggacagtctg aacaggttcc
    63421 atcgtttctt tattttctac gtcttcttct gtgtgtgttt cgtggttgtt cttctattgc
    63481 tggatcaatc gtgccataaa aggggcgatt gcggtcaagg taccagacat aaagaataaa
    63541 caatgcaata cataggacaa aaaggattgc acctatcgta aatccttcag gcaagtaact
    63601 gaaagtgaca gtatgtttac ctgctggaac ttttatcatc aagaatgcgt ctttgaaatt
    63661 gctgaccttg actggtttcc catcaatttt agctttccat cctttgtcat aaggaatagt
    63721 tgtcaccaac atggaatctt cagcggtatt tacagtccca gaagcttttc tgccagtggc
    63781 ttccatttcg acaccttttt ctttgatctg attcattgcg gcttgatagg ctacaacatc
    63841 tagaccaacg actttaggct ccatgaaact tatttctttc gtcccataaa aacttgcagt
    63901 aaatgtcact gttgtctctt gaggataata gccaagatca tagtattgac cagaaatgtt
    63961 gatttgcgtt tttcgcgatg taccattgac agtgatcgtc gcactagaac tttctaattg
    64021 cgcaaaattg gttgggaaca aacttaagta agcttgtgta tttgcaggca catggacttc
    64081 ccaagtgagc tcttttggct ggttatctgc tgtttctgag taagtgacgc cagtcgttgt
    64141 ctttgtgatc gtcgtattca actgattctt caaagtaggt gtatagaatg taaaatactg
    64201 ttcatttaga ccagacaatg tattgatcaa gtttgtctga ctggtcaaat tatctgtcac
    64261 tggctgctca acatcattaa cggacaacgg tgcagtaaat gctagtggca atgcattgac
    64321 attctgatac agtgtatagt cgccgctttg accagcttgg cggaagccat atttactgaa
    64381 cgtgctttcg tttttagaaa tgttatattt gattcctgta aacccatcca tcagcaaagt
    64441 attattgtta taacggatat tcaaatttgt ccctcttgaa cggaaaccta atttatccag
    64501 gtaagaggaa gaattacgat ttcttataga agaaaacaaa ctgataccac tgtaaccata
    64561 gttgatcgaa tcgtttgcag atactggatc cagattttcc aagcggtaaa acgagtcgga
    64621 atcttttttt gtttcattta caagagcttt caagtcagga taaggatcag tatataaact
    64681 gcgggaagca taattccaat catcaagaat gccatggatc atactgttcg tattgaccag
    64741 tgcttcagca gacatgatca ataataacaa tatactcaga tgattgaatg aaagtttttt
    64801 atgctgataa aatcccacag caaaagcata aatccctaag aaaaccactg tcaatacaaa
    64861 ggaagtcatc gtcacatagg tgtagcttcc ttcaggtttg atgccccatg ccaccgcaaa
    64921 gagagcagct acgaccaaaa tgattcctaa caacagccca cgatcgtctt gttctatctt
    64981 ttcccatcct tttcctgcaa gcaggagcac taagaaagag aacagatagg cataacggaa
    65041 taaaaacata ttcggtgcat gcataccatg ccagaacaaa ttcaatggaa caagataaaa
    65101 acttgcgata agtatggcga aaagactgcc gtacaaaaat ttatttttca acggtacttt
    65161 ccgactggca aaataaaaca gacagaggac taatggtagc agacctgcgt aaacgaacgg
    65221 aatcgatccg tattttgtcg tgtcataaac accaatcata tttttcatga ttagatccag
    65281 ataagaagtc gcttctgttt tcaacgtagt gatctgactc agtgcctcgc catttgaccg
    65341 aagatccagc actgctggca atacaatgat cattgaagcg ccgcctgcca gtaaagaagt
    65401 gataccataa ggaacaatcg tttttttata ttctgaccag tttgtcaata gacgggcgat
    65461 aaaatataag aaagaaaata cgccaatcat aaaacccata taaaaactgg ataaaaacaa
    65521 gagtaaataa ctgataaata aaagtttcgg ccgtttaaga tccataacac gatgaatccc
    65581 caaaatcact aatggaagat aaacaaatgc atccagccac atgatgatct ccgaatgtgc
    65641 agtgataaat gagatcaatg cgtaactgac gctaagtgca acatgccccc agcgaggaat
    65701 cttgaacgta cgtgcaagaa accaaaaagc caatccggca cagccgacct taagcaaagt
    65761 cagaacatac agtgcatctg gcatcatctg gtttggaaaa aagaacacca gtggcgtgaa
    65821 gatcccgcct agatagtaag aaattaaaga taaataattc aatcctagag aagcattcca
    65881 tgtataaaaa atactttgct ttccaagaag aacatttcgg aagctggcat gaaaattaga
    65941 aaactgtgaa aaggcatcac ttgccaaaat acttctgctg cttccaggat agattccgat
    66001 acttagataa acaagtgcta aaatcaaaaa cggaatcagg aaactagctg ctgcgtagcg
    66061 tccgttttct ctaaagaatg actttaaatt ttttttcata tttattttcc accaaatttc
    66121 tatgaagttg tattcagttt atcatatcct tgtttttctc tgcttaaaaa gagtctagtt
    66181 ttcacaaaaa aataaaattt agaataaata acttcataat ttgttcgtat aacaaaaata
    66241 aacgcaaaaa aagggtagga atcaaaagtc ccacccttaa aaatttttat taaataaaaa
    66301 accgttcact atctgaacgg tccaagtatc attcaattaa acgcgttcaa cttttcctga
    66361 tttcaaagca cgagttgaca cccaaacttt tttaggtttt ccgtcgacca taacgcgaac
    66421 tttttgtaag ttaggtttaa cagtacgttt tgttgagttc atagcgtgtg aacggttgtt
    66481 tccacttttt gtcttgcgac ctgtaaagta acaaactttt gccatggtaa tttcctcctt
    66541 tgccttgatt tggagcaata gaataattca gctcatacca gactaacata tcatatagaa
    66601 tgggaatttg caagtacatt ttcatagata caattgacaa ttgagaagaa taattgtaaa
    66661 ttaaacaagg ttatacctga aattttgcaa ggtttttgag tactttgggt aactgccttt
    66721 tatttcaagt tgcgctatga taaaatatga tagaagaaaa atgggagttt tttacccgtt
    66781 aaggaggctc attcatggct gtaaaaattc aaacgtcagc tggaaccatt gaaattacca
    66841 atgatgtaat tgcaacagtt gttggtggcg ccgcgacaga tgtgttcggt gttgtaggaa
    66901 tggccagcaa aaatcaaatt aaagataata ttactgagat tttgcgtaaa gaaaattact
    66961 caagaggagt agttgtccgc caagaagata atggtattgc tgtagatgtt tatacgatta
    67021 tcagctatgg tacgaaaatc tctgaagttt cccgcaacgt ccaagaaaaa gtgaaataca
    67081 atctagaggc attattaggc gtaactgcca attcagttaa tgtctttgta caaggtgttc
    67141 gtgtactgcc agactaggca ggagactggc tggtaactca gcagtcgatc tgaaggagga
    67201 ttatctaggt gagtgtaaca gaaataagtg caagccagtt ccaggaaatg gtccaggcag
    67261 gtgcgaatcg tctgcaagta aatgcagaat acgtcaattc attaaatgta ttccctgtgc
    67321 cagatggcga tacgggaaca aatatgaatc tatctatgac tagtggagct aaggcagtag
    67381 tagattcaac ctcagaaaaa gtaggagaat tagcagcaat gctttcaaaa ggattgctga
    67441 tgggtgcgcg cggaaattcc ggcgttattt tgtctcaatt gtttcgtgga ttttctaagc
    67501 aaattccaga tgttgtctca ttaaatgctt ctgatcttgc tgcagccttc actcatggag
    67561 ttgaaactgc gtataaagca gtaatgaaac cagtagaagg aacgattttg acagtagcta
    67621 gagaagcagc gaaagctgga gaaaagaaag caaaaagtac tgatgatgtc gttgaagtaa
    67681 tgacagctgt tgtaaaagga gcaaagcgtg ctttagctaa aactccagac ttgcttccag
    67741 tcctaaaaga agtcggtgtc gtagacagtg gagggcaagg actgctgttt gtttatgagg
    67801 gctttttaag tgcattgaat ggagaattcc aagcggatga aacatatgaa ccttctccag
    67861 cagaaatgga tgatatggtc aatgcagaac atcatcgcag tgtccaaggt caaatggcga
    67921 cagaagatat ccattttggt tactgtacag aaatcatggt aaaaatcgga gaaggaccta
    67981 cagtcgatag tacattcgat tacgaagaat tccgtaacta tttagatggt ataggagatt
    68041 ctttacttgt ggtcaatgat gacgagatca tcaaagtcca cgtgcataca gaaaacccag
    68101 gagaagtctt gaattatgga caaaaattcg gttcattagt caaaatcaaa gtcgacaaca
    68161 tgcgcttgca gcatgagacg attttggaac acgatgaaga agtgaacgag tttgcgaaaa
    68221 aagaaatacc acgtatcccg tatggtatcg tagcgatcgc tgctggtaaa ggcgtccaag
    68281 agctgtttga aagtttaggt gctaattatg ttatcagtgg tggacaaaca atgaatccaa
    68341 gtacggaaga cattgttaaa gcgattcaag aagtaaacgc agataaagtg attgtcttgc
    68401 caaacaataa gaacatcttc atggcagctg atcaagcagc agaagtagca gatatcccag
    68461 tagcagttgt tccttcaaga acgatttccc aaggattgac agctatgctt tcattcaatg
    68521 atcaagcttc tttagaagaa aacaaagaaa cgatgacaga aatgttgtct agcgttgtga
    68581 gcggtcaagt cactcacgcg atcagagata cctcaattga cggtgtagag atcaaagaag
    68641 gagacttttt gggcatgatc gatggaaaaa tcctgatctc taacccagat atcacagcaa
    68701 cagcgttaag tacactagaa caaatgatca atgaggacac agagatcgta acgatcttgg
    68761 caggtgatga aggaacagtt gaacaagcaa atgaatttgc tgagaaacta acagaaaaac
    68821 atcctgattt ggaaatcgag atccaccaag gagatcagcc tgtctatcct tatctatttt
    68881 ctgctgaata atttctgtgt cagaatatct ttctaacaca gtattcattc ataaaaggcc
    68941 ttcggttagt gatcaggtat gatcgctgac caagtccttt ttttgttaaa ggagggagga
    69001 aaaatttatg cgttctttag atgatccaat cactatgctg gcaggagtcg gagaaaaaag
    69061 agcagctagt cttgccagct tgggcatcca aacgattgaa gacttactga cttattatcc
    69121 ttttcgctac gaagatattc aggaaagaaa tctaaacgag atccaggatc aagaaaaggt
    69181 tactttgaaa ggaatcgtag tctcgcctcc tgtgatgaat cgatttggtt ataaaaaaag
    69241 ccgattgcaa tttcgtatga tgcaagaaca tgatgtgttc aacgtttctt tttttaatca
    69301 accttatcta aaagaaaaag tcattttatc ggaggaaatc gccgtatacg gtaaatggga
    69361 tgcaaagcgt aaagccttga acgggatgaa gattttaggt tctcaaacaa tggatgactt
    69421 ttcgccgata tatcacgtca acaaatcaat tcgtcaaacg acattagttg atctaatcaa
    69481 aaaagggttt caagaatacg gcacattgat tgaagaaaat ctgccaaaca accttgtgga
    69541 gaaatatcga ctgcttgacc gagcttctgc tgtaagaagt atgcattttc caaaagacca
    69601 cgaagaaaac catcaagcca aacgacgtgt cgtttttgaa gagttctttt tatttcaaat
    69661 gcgtcttcaa ggattgaaaa aagcagaaaa agcagaaacg aatggtttgg agatccttta
    69721 tgatgtccaa aaattgaaac aatttactca aaagctacct tttgaactga caaatgcaca
    69781 aaaacgtgta acgaatgaaa tctgtcggga tcttcgcagt ccgcagcata tgcagcgact
    69841 tttgcaggga gatgtaggta gcggaaaaac agtggttgcc gcgattgcgt tatacgctac
    69901 cgttacagca ggtttccaag gtgcgttgat ggtgcctaca gaaatcttgg cacaacaaca
    69961 tatggaaagc ttgcaacagc tgtttgatcc caatgaagta accatcgcat tgattacggg
    70021 gtcaacgaaa gcaaaagaac gacgtgagct ccttgaaaaa ctagagcaag gggaaattaa
    70081 cgtcgtgatc ggcacacatg cattgatcca agatggagtc gaatttcaga atttaggtct
    70141 agttattacg gatgagcagc accgttttgg cgtgaaccag cggaaagtac ttcgtgaaaa
    70201 aggctggcga ccagatgtct tatttatgac agcgactccg attcctagaa cattagctat
    70261 tacagcatat ggtgagatgg atgtatctat cattgatgaa cgtccagctg gacgtatccc
    70321 gatcgaaaca cgctgggtaa gaacacctca attggacagt gtactggatt ggacgaaaaa
    70381 agaactggca agaggacatc aaatgtatgt catctgtccg ctgattgaag aatcagaagc
    70441 attagatgta aaaaatgcag tggaaatcta tgaaaaactt cgtgaactat ttgcaccaaa
    70501 atatgaagtt ggcttgttac atggtaaaat gaagaatcag gaaaaagaag taatcatgga
    70561 agccttcaaa gacaaccaga tgcagatatt agtttcgact actgtaattg aagtaggggt
    70621 aaacgtgccg aacgcgaccg tcatgctgat catggatgcg gatcgatttg gattggcaca
    70681 gctgcaccaa cttcgtggac gtgttggacg cggaagtgat gcttcctact gtatcttagt
    70741 tgctaatcct aaaaatgaac taggtgtgga acggatgaaa atcatgacag agaccaccaa
    70801 tggttttgta ctaagcgaaa aagatctgga attacgtggt cctggtgaag tatttggctt
    70861 ccgtcaatct ggtctgcctc aatttgcgat tgctgacttg gtgacggatg gaaatgtttt
    70921 ggaggtagcc agagaagagg ctgcagccct ttggcaaata aaggattggc agatgcttcc
    70981 tgagtatcag cctttagcgc aaagcctcca aatagaaaat caggataatc gttatttcga
    71041 ttagcagact gtgctatact ttatactgat gacggaaaaa ggagtggaaa caatgaaaat
    71101 tgccgtagat gcaatgggcg gagatcacgc acctcaagca attgtagaag gcgtggcttt
    71161 agcgcagcaa gattttccag aagtagaatt cttactttac ggaaaagaag cagaaatcaa
    71221 gaaatactta acaaatgaaa aaaacatcac gattatccat acagacgaaa aaatcaatag
    71281 tgatgatgag ccagtaaaag caattcgacg aaaaaagact gcatcaatgg tccttgctgc
    71341 acaagcagtg aaaaacggtg aagcagatgc tgtattttca gcagggaata caggcgcgct
    71401 actagcagca gggttgttca tcgtaggacg tatcaaaaat atcgaacgcc ctggcttgat
    71461 gtctaccttg ccagtagtag ggaaagaagg tgccggtttc gatatgctgg atcttggcgc
    71521 taacgcagaa aacaaaccag aacatttgtt gcaatacggt attttaggtt ctttttatgc
    71581 acgtaaagtc cgaggtatcg gacgtcctcg tgtcgcactc ttaaacaacg gaacagaagc
    71641 aacaaaaggt agtgaagtga cgaaaaaagc ctatgaactc cttcagaatg aaacaagctt
    71701 gaattttatt ggaaacgtag aagctcgtga gctactcaat ggtgtggctg atgtagtggt
    71761 cacagatgga tttacaggca acgctgtttt gaaatctatt gaaggaacag caatgaatat
    71821 gatgaatcta ttaaaatctg ctattctaaa tgaagggatc aaaggaaaaa tgggcgctat
    71881 gcttttaaaa gacggcttac gttctttgaa agcagaaatg gattattcca aacatggcgg
    71941 tgccgttttg tttggcttga aagcaccagt cattaaaact catggagcaa caggccccga
    72001 tgctgttcgc tatacgatcc gccaaatcca cacaatgctt gagacagatg tagttggaca
    72061 attagtcgaa caatttgaaa aaagcgaaga atagtatttg gatatctgaa gcgatccgtt
    72121 ccattgaaaa aaaggtggac attcctgaaa aatgccagta aaattagcca tggtgtaggt
    72181 aattgacaag tgtatgattc ttggaggtga aaaagttgac tcgcgaagaa gtatttaaca
    72241 aagtagcgaa aattatttca aatcattttg agatagatac cgataaagtg acggatgaat
    72301 tgaacatcaa agatgattta aaagctgatt caattagtat tatggaattc gttttagagc
    72361 ttgaagatga attcggtacg gaaatttcag atgaagacgc tgaacaaatt gaaacagtcg
    72421 gtggcgcagt agattatatc agcagccatc ttaaataatt tcaaataaaa gcaaagaagg
    72481 ataaaaagct gcatgcagct ttttatcctt ctttttttaa tctttttgac acgtaaaagt
    72541 catttttctg ataattctgg cgataaacag aaattatgtt gcaaagtaaa gcggttttct
    72601 atataattat taataattca ttacacaaag ataagaataa cctttgttat aaaacgattt
    72661 attctgtgta atgtcctttt ttattaagaa aaacttccat ttaggaagca gagaggggta
    72721 ttcgattgtc cgataaccaa ttattagaag ttcagaacct acatacagga ttccgactca
    72781 aagatgacta ttacgatgca gtagatgacg tttcatttac tttagacaaa aacgagattt
    72841 tagcaatcgt tggggaatct gggtgcggga aaagtacctt ggctactacg attatgggat
    72901 tacttgatcc taataacaca aaaattacag gtgagatttt atataacgat ctgaatttaa
    72961 tcgacctgaa cgaaacgctc tataataaaa tccgcggaaa tgatatcgga atgattttcc
    73021 aagatccgtt gtctgcatta aatcctctca tgagaatcga agaccagatc aaagaaggac
    73081 tttcctatca cacaaagatg aatgcagaac agcgtcaagc tcgtgcacta gaattgctag
    73141 aacaagtagg gattcctaat cctgcgagag ttggacgcca atatccccat gaactatcag
    73201 gcggtatgag acaacgtgtc atcatcgcaa tcgcaatcgc ctgcaaacct ccaatcgtca
    73261 ttgcagatga accgacgaca gccctagatg taaccatcca agcacagatt cttgatttac
    73321 tgaaagacct tcaggaagaa acaaaaacag ggatcatctt gatcactcat gacttaggag
    73381 tcgtagcaga aatggctgat cgagtggcag tgatgtatgg cggacagttc gttgaagtag
    73441 caggtgtaaa agaactgttt gatcatccta agcatcctta tacacgctct ttactgaact
    73501 ctataccaca agaaggaaat catgatgcag aactccatgt gatcgaaggt gtcgttcctt
    73561 ctctgaaaaa catgcctcgt aaaggttgtc ggtttgcacc acgtattcca tggataccag
    73621 caagcgatca tgaagaagag cctatccttc atgaagtcgc accgaaccac ttggtacgtt
    73681 gctcctgcta taagcatttc cactttagag acgaaaaagg agaggtgtag atgacagaat
    73741 taatcacaat caaagacctg aaagttcatt accctattcg cagtggattc ttcaatcgag
    73801 taacggatca tgtatatgct gtagatggtg tggattttat tatcgaaaaa ggaaagacat
    73861 atggtttagt gggagagtct ggctctggaa aatctactac gggaaaagcc gttgtgggat
    73921 tagaaaaggt aacagccgga caaatcatgt atgaaggaaa agatgtaacg aagcgaagca
    73981 accgcaaaaa aatgggttat aacaaggatg tgcagatgat cttccaagat tcaatgtcca
    74041 gtttgaatcc taaaaagcga gtgttggata tcattgctga acccatccga aattttgaac
    74101 ggttaagcga tcaagaagaa aagaaaaagg taaaaggact gctagatatc gttgggatgc
    74161 cggaagatgc gctatataaa tatcctcatg aattttcagg cggacaacgt caacgtctag
    74221 gagtagcccg tgctgttgct accaatccaa aactgatcgt agccgatgaa cctgtatctg
    74281 ctctggatct atctgttcaa gcgcaagtat tgaatttcat gaaacgaatc cagcaagaat
    74341 acggcctcag ctatttattc atttcacatg atttaggtgt agtaaaacac atgtgcgaca
    74401 atatcgcaat tatgtacaaa ggtcgatttg tagaaatcgg tacaagagaa gacatttata
    74461 atgacccgcg acatatctat acgaaacgtc tgctttcagc tattccgcaa atcgatgtag
    74521 aaaataggga aagccacaaa gaaaatcgac gaagagtaga acaagagtat atccaaaacc
    74581 aaaaagaata ctatgatgcg actggtcgag tctacgattt gcgtacgatc acaactacac
    74641 acaaagtggc gttgaaagat ggaggtgcaa gctaatgtgg aaaacgattc tgcgacgtgt
    74701 tttattgatg atcccgcaag ttattatttt aagtgttctg atcttcttat tagcccaagc
    74761 gatgccgggg gatccattta ccggtttgat caatccaaat caggatccgg cagtgatcga
    74821 acagatgcga caagcagctg gcttgaatga cccatggtat gtccagtact tccgttggat
    74881 cggaaatgct ttgcaaggcg attttggtca aagtttctta tacaaacgct ctgttgctga
    74941 cttgatcggc gaacggatca tcaacacttt atatctatcg atcttgacag ttgtccttac
    75001 ttatttgatt gctgtgcctc tggggatgct tgctggccgg tatcaaaatt caatcttgga
    75061 taagattgtc gtaatctaca acttctttag ttttgctgtt cctttattta tcttcggctt
    75121 gatcatgcta tttgtttttg gttatcgttt aggctggttc ccaacaagtg gatcacaaac
    75181 actaggtttg caaggtggat ttatcactca atggatagac cgtttgaaat atattctgtt
    75241 accatcaatt acccaagcat ttttggcgac tgccgtcaca atccaatatc tgcgaagtga
    75301 agtaatcgat tcgaaatcgc tcgattttgt cagaacagcc cgttccaaag gggtaccgac
    75361 gaataaagta ttcagtcgac atattttccg aaatgcagcg ttgccgatgg cttctcaaat
    75421 ggggtatgaa atcacttcgt tgattgctgg ttctgtagtt atcgaaaaga tttttggtta
    75481 tccgggagtc ggaaaactat ttattgattc catcggccaa cgggactata ccgtgatcac
    75541 atccttagta ttgattttag gaatcgcgac gctagtgggg acattacttt cagatatcat
    75601 catgagtatc gttgacccgc gtattcggat tcaataaaac caatcagaaa ggagaatgga
    75661 tcgatgagtg aaaaaaacaa tacagcagtt caagaaagta ttcctcctat ggggatacga
    75721 atgattgctc gagaatttaa aaaagataaa attgctattt tttcattagg tttgctagtg
    75781 gttttattat tagtgatctt tatcggtgcg atgctgaccg atcaagacaa agtgatgtat
    75841 gttagtatct tcgacaaata cgctgcacca ggaacagttt cgacacaagg acaaaagttc
    75901 attctgggag cagatgaagg cggacgtgat gtattaggac aattgatcat aggtgctaga
    75961 aactctgtta cgatcggatt tgcgatcacg atccttactt cgatcatcgg ggttggatta
    76021 gggatcatct ctggctacta cggagggatc attgacaaca tcttgatgcg gatcgttgat
    76081 tttatcatga ttctaccgat catgctgatc attatcgtct tcgtatcgat tatttccaga
    76141 tacaatgtct ggtcctttat attcatcatg agtgcatttt attgggtagc taaagcccga
    76201 ttattccgaa gcaagacatt atctgaagca agaagagatt atgtcagtgc ctcaaaaaca
    76261 atgggaacca atgattttaa aatcatgttc cgcgaaatca tgccgaatct aagttcatta
    76321 atcattacta atttgacgat gaactttgcg gcaaacatcg gtatcgagac aactttgact
    76381 ttcttaggtt tcggcttgcc ggcaaatgta cctagtttag gtacattgat cggttatgca
    76441 agtaacggag aagtcttagt gaatcggcaa tggatctggt tacccgcatc aatccttatt
    76501 ttagttttga tgttgagtat caattatgtt ggacaagcat tcaagcgttc tgcagatgcg
    76561 cgccaacggt taggctagta tagaagcgaa gggggaaata ggaatgaaga aaacgatttt
    76621 tggatttgca gcgctgatgt ctgctgtcgt tcttgcagca tgcgggggcg gaggtacaga
    76681 tacctctgga aacaactctg gaggcaacgg caataacaaa gaggaattaa cttttccaat
    76741 tgcaacaaaa aataatgatg atgcaatcga agacggcgaa ttagaagctg cggtcgcaac
    76801 ggacagtcag tttaaaggat tgttccagtg ggagttttac caagattcat atgatgcagc
    76861 ttttatggct ccttctcatg aaccgctatt tgcaaacgat gacgatttca gaatcacaga
    76921 cgacggagct gcaacgcttg atctagatga agatacgaaa aaagcgacaa tcaaagtaaa
    76981 agacaacgtc aaatggtcag atggtgaaga tgtaacggcg gacgatgtga ttttccctta
    77041 cgaaatcatt gggaataaag attacactgg tatccgttat gacgacactt tccgtaacat
    77101 cgtaggtatg gaagaatatc atgatggaag tgccgacaca atctccggaa tcaaaaaaat
    77161 agacgacaaa acagttgaaa tcgaatataa agaagtaaac ccaagcatgc ttcaatcggg
    77221 tggtggtatc tggtcatatg cagcaccaaa acatacgtta gaaggtgtag caatcaaaga
    77281 tatggaatca agcgatcaag tacgtaaaaa tccagtgact tttggccctt attacatgag
    77341 taatatcgtt gcaggagaat cagtagaata cttgccaaac gagcactact ggaatggtac
    77401 gcctaaattg aaaaagatca cgatgaaatc tgtaccgatg gcaagtgcaa ctgaagcatt
    77461 gaactctaaa ttatatgata tgattttcca aatgccaaca gatacttacg atacctataa
    77521 agaaattgct ggctatacaa acttaggccg tgaacaaact tcttatactt atctaggatt
    77581 caagttaggt aaatggaatg cagatacaaa gagtgtggaa tacaatccag attcaaaaat
    77641 ggctgataaa tcattacgtc aagcaatggg ctatgcatta gataataatg cagtaggtga
    77701 acgtttctat gcaggtttga gaagcaatgc gacttcattg attcctccag tattccagtc
    77761 ataccatgat gatgagatga aaggattcac acaagatcta gacaaagcga aaaaactatt
    77821 agatgatgct ggctacaaag atgtggatga cgatggttta agagaagaca aagatggaaa
    77881 taaactaaca atcaactttg cttcgatgtc cggtggggaa acagcgcaac cattggcaga
    77941 ttactatatc caacaatgga aagaaattgg tttggatgtc caatacacaa caggtcgtct
    78001 gatcgaattc aattctttct atgataaatt agaaaacgat gatcctgaaa ttgatgttta
    78061 ccaagctgct tggaatacag gaactgatcc aaatccaagt ggactatggg gaccaaatgc
    78121 tgcgttcaac tacactcgtt atgaatcaga agaaaataca aaattgatca acgatatcag
    78181 ttcaagcaaa gcatttgatg aagagtacca aaaagaagca tatcaaaaat ggcaacaata
    78241 tgcatttgaa gaagcatttg cgattccaac gttgttccgt aatgaagtat tgccagtcaa
    78301 cgaccgtgtc aaagactggg attggtctta tgatgtacca aacccatggg caaatgtttc
    78361 tgttacagca gattcacgtt cataatcact aaaaatgacc gaaaaagggc gatgtccttt
    78421 ttcggttttt tgatattttt ctgtttattt ctctaatatt caggtcaagg cgctgatttc
    78481 atgacttctc caataaacgg tgttcaaagt ccagtttctc ggtattaagt caaatttatg
    78541 caaaaatatg gaaagccatt ttcacaaaat tttttcttca tactcgaaac taaacgaatt
    78601 tttcacaact tctcgtcaat cactaggatt attaaagctt tacttacctt ttgaccgaac
    78661 catttcaaat ttgacaaaaa accagtataa taaggaagta tcgaaaaaat atccataaaa
    78721 ggaatgtgga aaatggacaa ccagctgaca aaagaactaa aagaaaacta taacatcgtt
    78781 tttcacgatc taaatttgct tgaacaagct tttacccatt catcctatgt gaatgagcat
    78841 cgcaatctgc aattatcgga taatgagcga cttgaatttt taggagatgc cgttttagaa
    78901 ctgatggttt ctcagtattt attccgttta tatcctcatt tgccagaagg aaaattgaca
    78961 aaaacacgag ctgcgatcgt tcgcgaagac agcttgtcga aatttgccaa agaatgtcac
    79021 tttgatcaat atgttttgtt gggcaaggga gaagagaatt caggaggacg tacgcgacca
    79081 gcattgcttt gcgacctatt cgaagctttt ttaggcgcgt tatatcttga ccagggattc
    79141 gacacgaccc atgcattcat cgaaaaagtg atttttccta aagtcaaagc aggtgctttt
    79201 tcacatgaga tggatcataa aacaaaacta caagaagtct tgcaaaaatc aggtgatgta
    79261 tcaatcgaat accgattgat caatgaagaa ggtccagctc atgaacgagt attttggatc
    79321 gaagtttatg tagatgatca attgattggc actggacaag ggaaatcgaa aaaattagca
    79381 gaacaagctg cggcggaaaa tgcattggca gcactgtaaa agtaagtgag ggaaagcttt
    79441 gtatttgaaa cgaattgaaa tagccggttt taaatcattt gcagacaaga cagtcattga
    79501 ttttgaaaat agcgtcacag cagtggttgg accaaatggc agcggaaaaa gcaatattac
    79561 agaggctatc cgctgggtat taggagaaca atctgctaaa agtctgcgag gcggaaaaat
    79621 gccggatatc atctttgccg gttccgatac ccgtaagcag ctgaatattg cagaagtcac
    79681 agtgatttta gacaatagtg atcattatct gccattggag tacaatgaga tcagtgtaac
    79741 ccgccgttat cgacggactg gggaaagcga gtttttcatc aataaacaaa gctgcagatt
    79801 aaaagatatc caagaattgt tcttagattc tggattagga aaagaatcgt tctcaatcat
    79861 ttctcaagga aaagtagaag cgattttcag tagtaaaccg gaagaccgtc gtgggatctt
    79921 tgaagaagca gctggtgtct tgaaatacaa gcagcggaaa aagaaagcag aacagaagct
    79981 ttttgaaaca gaagacaacc tcagccgcgt ccaagacatc atccacgaat tggaagaaca
    80041 gttaactcct ttggccgccc agagtgaggc agcaaaggag tttttacggc taaaagaaac
    80101 actgactcaa accgatgtct ctttgatggt tgctgaaatc aagacagcaa aaaaagattg
    80161 ggacaacaaa caagcacagc ttgcgaaatt caatctagaa ttaggcaaac tatctgagtc
    80221 gatccaagaa caagaatcca ttttggcgaa gcagcgtaaa gaaaatgcgc aagccgatcg
    80281 tctgatcgaa aaaaatcagc aagtattatt agatctttcg gaaaaactga agcagacaga
    80341 aggacaaaaa gatgttttgc aggagcggac aaagcataca caaaaaagct cgcaagaata
    80401 tcaaacttca ttagcagaag cacaaaaaaa ggttaaacat tttgaaaagc ttcaagaaag
    80461 cttgatgaaa gcagcagcag aaaaagaaac agagatccaa aaagctgaag caaatctcat
    80521 aaaaacacag caagaattag aaaaatacca aaaatcaacg aaagaattat tggcagaatt
    80581 aagagatcaa tatgttgatt tgatgcaaga acaagcagct gtaggaaacg aactgaagta
    80641 tctagaacgt caatatatac aagaaacagc aaaaagcaag cagacgttag ccaagcaatc
    80701 ggaagtagaa gcatcagtag accgattgat cttacaaaaa gaagaattga cacaaaagca
    80761 ggcgcagcta aaatcatctt taactgaaac aaaagagaag ttagaaatga tccaacaaaa
    80821 cgggaaaaag ttccaagaag cattagcaaa agaacagcct aaaatgtatc aattaatgaa
    80881 tcaagtccag cagctacgtg ctcgtaagaa aagccttcaa gaaatccaag aaaactattt
    80941 tggtttttac caaggggttc gattggtctt gcagcataaa cagcagcttt cgggtattgt
    81001 cggagcagtg gctgaactga tcgatgttcc tgcagatttc acgttagcta tcgaagcagc
    81061 tttaggtggg gcagcccagc atgtcatcgt tgaaaatgaa aaagatgctc ggcaagccat
    81121 cacgtatttg aaacagcaaa gaggaggaag agcaacattc cttccactga cgacaatcaa
    81181 accaagacaa ttaccggctc atatattgac acaagcagca gctgtagaag ggtttatagg
    81241 gattgccagt gaacaagtca gttatcccga tcaaatccaa actgtggttc aaaacctgct
    81301 aggaacgatc cttttagcca aagacttaac tagtgccaat gcaatcgcgc aaacgatccg
    81361 ctatcaatat cgagtggttt ccttagaagg tgatgtgatg aatgccggag gatccatgac
    81421 aggtggagcg aataaacgag gaaaccaagg cagtttgttt gtacaaaatc aagaattgaa
    81481 acagttgact agtgaatttg aagaagcaga taaacaactc caagcacaag aaaaaaaagt
    81541 tcaggagctg caacaagaaa cagctcgttt agccgaagaa caagaagttt tgcgtacacg
    81601 aggcgaacaa ttacgttttg aagaacaaga agcgacaaat cagctacaaa acatcataaa
    81661 tgaacttgaa cgttttgaaa aagaaaagca aatctcaact tttgagacac gtgaactgca
    81721 gcagtttatc gaagattacg aaaagcaaac gaacgaattg aaagacaaac aaacagatct
    81781 tgaatcgcaa cgacaaaaaa tcgacgaaga aatcaaatcg ttaagtcaag aaagcgacca
    81841 gatggaagcc agaagagcac aagtacaaag tcaaaaagca caagaacaag cagatcttgc
    81901 tgtcttgaaa gagcagttta atcatctgca gatccagctc cgcggtgccc gagtccaaaa
    81961 agcagaggca accgaacgtc aagaagcgat agaaaagcag ttggcgacat tgacagcaga
    82021 cttttctgat catgaagtca cagaagaaag tttggaaaaa caaattaacg aattatctgc
    82081 tcagcgagaa acattaaaag ccgagttggc aaaagccaaa gagcagcgag atagaaggca
    82141 aaaggagatc gataagcttg aagcagtctt ggcagagcgt aatcgtgagc aaaaagcacg
    82201 actgtcggaa caatccaaat tagaagtcca aaaagaccga gctgaaatga ttttagataa
    82261 tcatttgacc tatctgcagt cagaatatca gctgacattt gagaaagctt cccaagacta
    82321 tcaagaaaca accgatatcg aagacagtag aacaaaggtt tcatccttaa aagaacagat
    82381 tgaaaaactg ggaccagtaa acttaaattc aatcgaacaa tacgaacaag tcagtgaaag
    82441 acatacattc ttagcaacac agcgagatga tctgttagca gcgaaaaacc aattgtttga
    82501 aacgatggat gagatggatg atgaagtgcg gacaagattc aaagaagtat ttgaagctat
    82561 ccgtcaagaa ttcaaaattg tctttccaaa tatgtttggc ggcggtaaag ctgaattagt
    82621 actgacggaa ccaactgatt tgctgaaaac aggtattgag attgaagtac aacctcctgg
    82681 caaaaaactg caaagtctaa gtttgctttc tggaggagaa cgagcactta cagccatcgc
    82741 gttgctcttt tccattatcc gtgtctgtcc tgttccgttt tgtatcttag atgaggtaga
    82801 agcagcgtta gatgaagcca acgtgaaacg ttttggtcgt tacttgagcg atttccaaga
    82861 tgacacacaa tttatcgtag tcacacaccg caaaggaacg atggtcgcag cagatgtact
    82921 gtacggagtg acgatgcagg aatccggtgt atcaaaaatc gtttctgtac ggatggaaga
    82981 tatcaatgaa gaggcgaaaa tcaacgaaac gaaagtgtag gaacgaaaat gatcaaatta
    83041 gtagcaatcg atttggacgg tacattatta aatgaacaaa agctgatttc agatgagaat
    83101 aaacaagcat tagcacaagc aaaacagcaa ggggtcaaga tcgttctatg tacaggacgc
    83161 cccttagctg cgatggcgca ttatctgcaa gaattaggac tggtagatga aggtgactac
    83221 agcatcactt tcaacggcgg tttggtacaa aaaaatgata ctggtgaaat catggaaaag
    83281 aaagtgatgg aagtatcaga tatccaacgc ttatacaaac tggctcagca attggatctg
    83341 ccactagatg ttttgtctga caatgtggtt ttacagctgc ctagtgcccc aaggaagcaa
    83401 tccttgtaca atgtgttgaa taagctgctg caattccaac cagcggatat aagcgatatt
    83461 acagatgaat ttgtgcttaa taaggcagta atcgcttatg accaagaaga attagatcct
    83521 aaaatcaaag aaataccagc agaattccat gaaatgtatg agatcatcaa aacaagaagt
    83581 atgcttttgg aatttatgcc aaaaggtgtt acaaaagctt atggtatttc tttattggca
    83641 aaagatcttg gtttgaaaca agaagaaatc atggcgatcg gtgatgagga aaatgattta
    83701 ccgatgatcc aatatgctgg actaggcgta gcgatggaga atgctgtgcc tttcgtcaaa
    83761 gaagcagcag atttcgtgac agccagcaat gaagaaaatg gcgtagccaa agtgatccaa
    83821 aaatttgtat tagagtaggg ggagtcaaat gggatttttt gataaaatca agcgtgcttt
    83881 tactggcgaa gagaaaacag aagaagttga agtacaggag aagtacgaca agggtttaga
    83941 aaagacgcgt aaaacatttg gtgaacggat gaatgagttg tttgccaatt ttcgaacagt
    84001 cgatgaagac ttttttgaag aattagaaga aacacttatc ggtgcagatg taggttttga
    84061 aacagcgata cgaatcaccg aagcattacg tcaagaagtg aaactcagaa atgcgaaaaa
    84121 atcggcagaa gtccaaaatg cgatcatcga gaaacttgtg gatctctatg aagcggaagg
    84181 aatcaatgaa gtaaatgaac taaatatcca agaagacgga ctaacagtta ttttgtttgt
    84241 cggtgttaat ggtgtaggga aaacaacaag tattggtaaa cttgcccatc agttcaaaaa
    84301 cgaaggtaaa aaagtattga tggcagcagc agataccttc cgcgctggag caatcgacca
    84361 gttagttgtc tggggcgaac gcgctggtgt tgaagttgtt cgtggcaatg caggaggcga
    84421 tccagcagct gtcgtattcg atgctttgga aagagcaaag acagagcagg cagatgtttt
    84481 actagttgat actgcaggcc gactgcaaaa taaagtgaac ttgatgaacg aattagaaaa
    84541 aataaaacga gtaatccagc gggaattacc agaagcaccc caagaaacac ttcttgtatt
    84601 agatgcaacc actggtcaaa acgcgatggt tcaagcaaaa caattcaaag aaacaacaga
    84661 tgtgaccggt cttgttttga caaaattaga tggtacagca aagggcggta tcgtacttgc
    84721 tatccgtaat gaattgcatt taccagtgaa attggtcggt cttggtgaag gaatcgatga
    84781 cttggagccg tttgatccaa atgattttgt cgttggattg ttcaaaggat tactaaaaga
    84841 agaataaccc atgtctaaaa agcaggagct gtgacaaaag ttgcagctcc ttgtttgaat
    84901 gattgttttt aacatagctg tgtttttgat gccttcattt ttatacttat ttgtaagcgg
    84961 ttctcaaaca atttcgttct ttttcttaga ctttttgatt ataattagat tcatatgaat
    85021 tggaggtcac ttaatgatga attttaagca attattattg catgtcaatg cgcgcccttt
    85081 tatcgaccaa gctcgatttg gtatagaacg ggaaggacag cgggttgatc ttgcaggaaa
    85141 tctagcaaaa accgatcatc cagcaatctt tggcgatcga tcctatcacc cctatatcca
    85201 aacagatttt agcgaaacac aaacagagat gatcacccct gttaccgatt ctattcccga
    85261 attatttcag tatctcgctg ctgtttatga tgtgactgct cgttctatac cgaaagaaga
    85321 gatgatctgg ccattaagta tgccacctgc cttaccggaa aaagacgaag agatcattat
    85381 tgcaaaatta aaaaatttcg aagatgtctt gtatcgacgt tatttagcaa aaaaatacgg
    85441 gaagcgaaaa cagatggtaa gcggtattca tttcaatttt gaatttggcg atgagttgct
    85501 aagaacattg ttcagccatc aggaagaatt tcaagatttt tccgaattca aaacagaact
    85561 ttatttgaaa acagcgagaa actttatgcg ctatcgctgg atgatcactt atttattcgg
    85621 tgcttcacca atgagtgaga agaactactt tttagatgaa tcacatccgc aagaacctgt
    85681 tcgcagtatt cgcaacagtg cgctgggcta tacgaatcat ccaaatgtga aagtttccta
    85741 tgcttctatg aaacagtatt tagcagatat cgagcgaatg atcgaagaag ggaaactttc
    85801 ggaggagaaa gaattttata caccgcttcg tttccgaggc ggaaagaaag tcgcagattt
    85861 agcaacaaca ggtgttcgtt atattgaatt gcggaatatc gatttgaatc cttatgcaag
    85921 attgggtatc aatccagagc aagttcggtt cttacaatta ttcctgatgt acatgttatg
    85981 gacagaagaa aaagaagact gtgaccaatg ggtagcagaa ggtacgactc gaaataacaa
    86041 agtagcacta gaacaaccat cagatcaaac agaatttcat caagaaggta gagaaattct
    86101 tgaaggaatg aagcaaatgc tggttgaatt ggattggttg gattctcttt atttagtaga
    86161 ggaagcattg actcaaatgg atcatcctga acaaacgtta gcagcgaaac tctatcaaga
    86221 agcacagcta tcgagtcagc aagaagttgc tgtggcattg ggacatcaat attataaaga
    86281 aagccatgaa cgtccctatc agttggccgg ttttcgcgaa atggaacttt ctactcagat
    86341 atttatgttc gatgccatcc aaaaaggtgt ccaagtcaaa gtattagatg agtcggatca
    86401 atttttgcgt ctgcaattcc aagaccatgt agaatatgtg aaaaatgcaa acatgacaag
    86461 taaggacagc tatatcgtcc cacttatcat ggaaaacaaa acagtaacga aaaaagtctt
    86521 aaaagaagct gggttccggg taccaggagg cgcagaattt tcatccatgg aagaagcggt
    86581 aaaagcttat ccgagatttg ccgagcaggc atttgtgatc aaacctaaat caaccaatta
    86641 cgggttaggt atcacgattt tcaaggaagg agctagtctg gaagattatc aagcaggttt
    86701 agccattgct tttcgtgaag acagttcggt tttagtagaa gaatttatgc cgggaacgga
    86761 atatcgtttc tttgtgatcg acggagaagt ccaagccatc atgttgcgag tccctgctaa
    86821 tgttattggt gacagtatcc gaacagtgaa agaacttgtt gaagaaaaaa atagtgaccc
    86881 tttgcgtgga acgaatcatc gtgcaccttt agaattgatc caattaggtg aattagaaca
    86941 attgatgttg aaagaacaag ggttgacgat cgaatcagtt ccccaagcca atcaaattgt
    87001 ttatctaagg gagaactcaa atatcagtac aggtggtgat tcgatcgata tgactgatga
    87061 attttctgaa gcttacaaaa aaatcgccgt ttctgcggta gaagcactag gagctaagat
    87121 tagtggtatc gatttgatta taccagataa agaaatcgat cctacaactg ataaaaaagc
    87181 atatgggatc atcgaagcaa atttcaatcc agccatgcat atgcatgttt atccttttgc
    87241 aggaaaaggc agaagattga cgatgaatgt attgaaattg ttatatcctg aagt
//
LOCUS       DAZKPE010000004        85534 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000004 DAZKPE010000000
VERSION     DAZKPE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 85534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.004"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(83..511)
                     /locus_tag="ACG930_000273"
     CDS             complement(83..511)
                     /locus_tag="ACG930_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517469.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(539..1177)
                     /locus_tag="ACG930_000274"
     CDS             complement(539..1177)
                     /locus_tag="ACG930_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517470.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(1181..3217)
                     /locus_tag="ACG930_000275"
     CDS             complement(1181..3217)
                     /locus_tag="ACG930_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFQ0517471.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            3343..4008
                     /locus_tag="ACG930_000276"
     CDS             3343..4008
                     /locus_tag="ACG930_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517472.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(5939..9088)
                     /locus_tag="ACG930_000277"
     CDS             complement(5939..9088)
                     /locus_tag="ACG930_000277"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFQ0517473.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWDNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGFYQAFNQIKKYAEEGIFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(9101..10288)
                     /locus_tag="ACG930_000278"
     CDS             complement(9101..10288)
                     /locus_tag="ACG930_000278"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFQ0517474.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTGDWE
                     DRKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLELEEDKYANKGD
                     LLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDKEKIKESTNGT
                     TMVHVTKGGIEQRTFQFPPDINEQQKIGNFFKQLDDTIALHQRKLDLLKETKKGFLQK
                     MFV"
     gene            complement(10278..11873)
                     /locus_tag="ACG930_000279"
     CDS             complement(10278..11873)
                     /locus_tag="ACG930_000279"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFQ0517475.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            complement(12382..13164)
                     /locus_tag="ACG930_000280"
     CDS             complement(12382..13164)
                     /locus_tag="ACG930_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517476.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTNTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(13229..14065)
                     /locus_tag="ACG930_000281"
     CDS             complement(13229..14065)
                     /locus_tag="ACG930_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0517477.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEIGASANQDELLYLTLHISR
                     VY"
     gene            complement(14083..15492)
                     /locus_tag="ACG930_000282"
     CDS             complement(14083..15492)
                     /locus_tag="ACG930_000282"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0517478.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(15506..17329)
                     /locus_tag="ACG930_000283"
     CDS             complement(15506..17329)
                     /locus_tag="ACG930_000283"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0517479.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGSIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(18173..18499)
                     /locus_tag="ACG930_000284"
     CDS             complement(18173..18499)
                     /locus_tag="ACG930_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517480.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYSLNRTCDDVTITHENGDNTYRAKAILDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(18545..18907)
                     /locus_tag="ACG930_000285"
     CDS             complement(18545..18907)
                     /locus_tag="ACG930_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFQ0517481.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(18944..19158)
                     /locus_tag="ACG930_000286"
                     /pseudo
     CDS             complement(18944..19158)
                     /locus_tag="ACG930_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            19286..19621
                     /locus_tag="ACG930_000287"
     CDS             19286..19621
                     /locus_tag="ACG930_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517482.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(19697..21694)
                     /locus_tag="ACG930_000288"
     CDS             complement(19697..21694)
                     /locus_tag="ACG930_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517483.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(21792..22067)
                     /locus_tag="ACG930_000289"
     CDS             complement(21792..22067)
                     /locus_tag="ACG930_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517484.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            22299..23033
                     /locus_tag="ACG930_000290"
     CDS             22299..23033
                     /locus_tag="ACG930_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517485.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            23072..24214
                     /locus_tag="ACG930_000291"
     CDS             23072..24214
                     /locus_tag="ACG930_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0517486.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(24309..25700)
                     /gene="sufB"
                     /locus_tag="ACG930_000292"
     CDS             complement(24309..25700)
                     /gene="sufB"
                     /locus_tag="ACG930_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFQ0517487.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(25705..26175)
                     /gene="sufU"
                     /locus_tag="ACG930_000293"
     CDS             complement(25705..26175)
                     /gene="sufU"
                     /locus_tag="ACG930_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFQ0517488.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(26162..27397)
                     /locus_tag="ACG930_000294"
     CDS             complement(26162..27397)
                     /locus_tag="ACG930_000294"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFQ0517489.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(27394..28680)
                     /gene="sufD"
                     /locus_tag="ACG930_000295"
     CDS             complement(27394..28680)
                     /gene="sufD"
                     /locus_tag="ACG930_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFQ0517490.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(28693..29466)
                     /gene="sufC"
                     /locus_tag="ACG930_000296"
     CDS             complement(28693..29466)
                     /gene="sufC"
                     /locus_tag="ACG930_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFQ0517491.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(29663..30511)
                     /locus_tag="ACG930_000297"
     CDS             complement(29663..30511)
                     /locus_tag="ACG930_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0517492.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(30535..31221)
                     /locus_tag="ACG930_000298"
     CDS             complement(30535..31221)
                     /locus_tag="ACG930_000298"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFQ0517493.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(31214..32248)
                     /locus_tag="ACG930_000299"
     CDS             complement(31214..32248)
                     /locus_tag="ACG930_000299"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517494.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(32311..32567)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32643..32981)
                     /locus_tag="ACG930_000300"
     CDS             complement(32643..32981)
                     /locus_tag="ACG930_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFQ0517495.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(32983..33339)
                     /locus_tag="ACG930_000301"
     CDS             complement(32983..33339)
                     /locus_tag="ACG930_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFQ0517496.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(33345..34532)
                     /locus_tag="ACG930_000302"
     CDS             complement(33345..34532)
                     /locus_tag="ACG930_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0517497.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(34723..35568)
                     /locus_tag="ACG930_000303"
     CDS             complement(34723..35568)
                     /locus_tag="ACG930_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0517498.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            35802..36767
                     /locus_tag="ACG930_000304"
     CDS             35802..36767
                     /locus_tag="ACG930_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFQ0517499.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            37144..38187
                     /locus_tag="ACG930_000305"
     CDS             37144..38187
                     /locus_tag="ACG930_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFQ0517500.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(38249..38713)
                     /locus_tag="ACG930_000306"
     CDS             complement(38249..38713)
                     /locus_tag="ACG930_000306"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFQ0517501.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            38959..39906
                     /locus_tag="ACG930_000307"
     CDS             38959..39906
                     /locus_tag="ACG930_000307"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0517502.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(40117..42189)
                     /locus_tag="ACG930_000308"
     CDS             complement(40117..42189)
                     /locus_tag="ACG930_000308"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0517503.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(42122..42499)
                     /locus_tag="ACG930_000309"
     CDS             complement(42122..42499)
                     /locus_tag="ACG930_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFQ0517504.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(42628..43188)
                     /locus_tag="ACG930_000310"
     CDS             complement(42628..43188)
                     /locus_tag="ACG930_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0517505.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            43338..44630
                     /locus_tag="ACG930_000311"
     CDS             43338..44630
                     /locus_tag="ACG930_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFQ0517506.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(44690..45808)
                     /locus_tag="ACG930_000312"
     CDS             complement(44690..45808)
                     /locus_tag="ACG930_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFQ0517507.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(45822..47243)
                     /gene="arcD"
                     /locus_tag="ACG930_000313"
     CDS             complement(45822..47243)
                     /gene="arcD"
                     /locus_tag="ACG930_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFQ0517508.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(47489..48610)
                     /gene="mnmA"
                     /locus_tag="ACG930_000314"
     CDS             complement(47489..48610)
                     /gene="mnmA"
                     /locus_tag="ACG930_000314"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFQ0517509.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            49014..49613
                     /locus_tag="ACG930_000315"
     CDS             49014..49613
                     /locus_tag="ACG930_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0517510.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(49751..51037)
                     /gene="efmA"
                     /locus_tag="ACG930_000316"
     CDS             complement(49751..51037)
                     /gene="efmA"
                     /locus_tag="ACG930_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFQ0517511.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(51308..51652)
                     /locus_tag="ACG930_000317"
     CDS             complement(51308..51652)
                     /locus_tag="ACG930_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFQ0517512.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(51789..52934)
                     /locus_tag="ACG930_000318"
     CDS             complement(51789..52934)
                     /locus_tag="ACG930_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFQ0517513.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(53114..54088)
                     /locus_tag="ACG930_000319"
     CDS             complement(53114..54088)
                     /locus_tag="ACG930_000319"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFQ0517514.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(54168..55043)
                     /locus_tag="ACG930_000320"
     CDS             complement(54168..55043)
                     /locus_tag="ACG930_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFQ0517515.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            55173..57080
                     /locus_tag="ACG930_000321"
     CDS             55173..57080
                     /locus_tag="ACG930_000321"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFQ0517516.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(57621..60899)
                     /locus_tag="ACG930_000322"
     CDS             complement(57621..60899)
                     /locus_tag="ACG930_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFQ0517517.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(61170..61715)
                     /locus_tag="ACG930_000323"
     CDS             complement(61170..61715)
                     /locus_tag="ACG930_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFQ0517518.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(61727..62419)
                     /locus_tag="ACG930_000324"
     CDS             complement(61727..62419)
                     /locus_tag="ACG930_000324"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFQ0517519.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(62438..62722)
                     /gene="macP"
                     /locus_tag="ACG930_000325"
     CDS             complement(62438..62722)
                     /gene="macP"
                     /locus_tag="ACG930_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFQ0517520.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(62735..63298)
                     /locus_tag="ACG930_000326"
     CDS             complement(62735..63298)
                     /locus_tag="ACG930_000326"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFQ0517521.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            63526..64188
                     /locus_tag="ACG930_000327"
     CDS             63526..64188
                     /locus_tag="ACG930_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFQ0517522.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            64312..65508
                     /locus_tag="ACG930_000328"
     CDS             64312..65508
                     /locus_tag="ACG930_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFQ0517523.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(65609..66985)
                     /locus_tag="ACG930_000329"
     CDS             complement(65609..66985)
                     /locus_tag="ACG930_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0517524.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(67022..67888)
                     /locus_tag="ACG930_000330"
     CDS             complement(67022..67888)
                     /locus_tag="ACG930_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFQ0517525.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(67977..69002)
                     /locus_tag="ACG930_000331"
     CDS             complement(67977..69002)
                     /locus_tag="ACG930_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0517526.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(69020..69694)
                     /locus_tag="ACG930_000332"
     CDS             complement(69020..69694)
                     /locus_tag="ACG930_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0517527.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(69878..70771)
                     /locus_tag="ACG930_000333"
     CDS             complement(69878..70771)
                     /locus_tag="ACG930_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0517528.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(70845..72542)
                     /locus_tag="ACG930_000334"
     CDS             complement(70845..72542)
                     /locus_tag="ACG930_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0517529.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(72535..73848)
                     /locus_tag="ACG930_000335"
     CDS             complement(72535..73848)
                     /locus_tag="ACG930_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFQ0517530.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(73848..77789)
                     /locus_tag="ACG930_000336"
     CDS             complement(73848..77789)
                     /locus_tag="ACG930_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0517531.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(77898..78356)
                     /locus_tag="ACG930_000337"
     CDS             complement(77898..78356)
                     /locus_tag="ACG930_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0517532.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(78654..79172)
                     /locus_tag="ACG930_000338"
     CDS             complement(78654..79172)
                     /locus_tag="ACG930_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0517533.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(79174..79791)
                     /locus_tag="ACG930_000339"
     CDS             complement(79174..79791)
                     /locus_tag="ACG930_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFQ0517534.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(79788..80642)
                     /locus_tag="ACG930_000340"
     CDS             complement(79788..80642)
                     /locus_tag="ACG930_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517535.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(80639..81550)
                     /locus_tag="ACG930_000341"
     CDS             complement(80639..81550)
                     /locus_tag="ACG930_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517536.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(81591..82925)
                     /locus_tag="ACG930_000342"
     CDS             complement(81591..82925)
                     /locus_tag="ACG930_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0517537.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            83133..83963
                     /locus_tag="ACG930_000343"
     CDS             83133..83963
                     /locus_tag="ACG930_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFQ0517538.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(84207..84456)
                     /locus_tag="ACG930_000344"
                     /pseudo
     CDS             complement(84207..84456)
                     /locus_tag="ACG930_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(84647..84841)
                     /locus_tag="ACG930_000345"
     CDS             complement(84647..84841)
                     /locus_tag="ACG930_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517539.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(85346..85531)
                     /locus_tag="ACG930_000346"
     CDS             complement(85346..85531)
                     /locus_tag="ACG930_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517540.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
BASE COUNT        24964 a        17968 c        14769 g        27833 t
ORIGIN      
        1 tgaatatatt aaaactacca aaaataactt ttaacgctgt ttcattatat gttttttcta
       61 ttttatataa acttttggat acttaatacc aaccggttgg attgtaccaa catgagaatg
      121 tgtcagttct atttcctgtc gcacttgcat aggcccatac tccttttgtt gcatttgctg
      181 atcgaataga gtttccaact ttcgcttttg caccgtgacg attatagaca cgactatagt
      241 ggttagaatg acctgttttt ctcgtacaag ttgtatcact ataataaacc catcttccag
      301 agctatgatt aattgctgtt ctagaaattt cccggtctac tggtaaattt gacttaataa
      361 tattaccttt agcatcaaaa tgaatctctc ctggctttaa agatttgtaa tagatttcac
      421 cgtgaactga atttgcttcc acttcagatg acatagcgtt tcctccaaca aaacctatcc
      481 ctagtgcaca aataataact gcttttttca taaaacgaca tcctttcctt tttgattttt
      541 aaagcatgat cttcttgttt cctattttgg tcagatatgg atcatgcgtg actacgataa
      601 ctaacgtacc ttgggaagct tgttgcgata agatttcaac tactttatcc ttatttcttt
      661 tatccaatga cccagtcggt tcatcggcta aaatgatttt gctattcttc aataagactc
      721 tcgcacaggc gattctttgc ttctcaccac cagataatgt gtagataggc gtacttagct
      781 tcttgtttat atttactttt ttcaatgcct catactttgc tgttcgctta tctgaaacat
      841 ttaaattcga aaacttcaat ccaatatcta aattaaaatc gattgtttca tattcaatca
      901 acccaaaatc ttgaaaaaga aaagatatgg tatttctttt tatcaagcgc ttctctctcc
      961 cagttaattg tttcgtctct tgatcgaaca aatagaattg tcctgaactg aactgatcat
     1021 tcaatcctaa tatattcaat aacgtacttt tacctgctcc actttctcca acaacagtca
     1081 caagatcccc agcatccgca gtgaaacgat ccaaatgaag aatcgttttg tttcgaatga
     1141 tttttttcgc accttttatc actatcaacg gctccaattg ttaacctcca ttcatcagca
     1201 ataactgact tttcttttct gtagacaaaa taaaaacaac tgaaagaata aaatcaatga
     1261 agctaaagaa aaaaatatta aaaagatatt taggctctct ttctataaga aaaaggaaga
     1321 ttacacttgt cgttccccat ttgatgaggt tcatcatgaa gaaatcttta tacgtttcaa
     1381 agagcgaata accacttgaa cgaaagatag cgattttccg acaattgtag acaaaatata
     1441 tgcataacat gacatagctc aacaagaaga aagaaaagaa agtgagtaaa aatatctgta
     1501 tcaagtaatg aaatgatctg cttaacactt tgacagctat ctcttcagtc tgagtatacg
     1561 gaaatgataa ctgcaagtta tcacgtaact gactttcttc aatcagctca aataaccttt
     1621 ctttcgacaa agagcctatc ttgatcttta acggtggata gatttctccg ctgagaatat
     1681 ttctttccaa atacatactg tttttcaatg tcagtatttc aacaaccgga taatgttcga
     1741 tccaggggat agaaggaata aatgtataaa tgggttgatt gttttttata aatagaaatt
     1801 tcggttcttt ttcactgatt tcttgataat attctgttat ttgcgccagg tcatttttta
     1861 aatctgtatg tctatatcgt tcagggatca atataacagg gtgcgtttct ttttcggtta
     1921 tttggatcaa ccttccagag acatcaatca aaggaaattt cttaagataa ttcagattta
     1981 tttttatccc tctgccaaac tgttcatttt cttcattcaa gtaatctgat acattgacta
     2041 atatacttcc gtttttattc aaagtttcat ataattcctg atctgctgct gatgcaaaac
     2101 gattggaata aataaaatcc acgtggtttt tcccgatggt tactggataa aatacatgat
     2161 agtcctcacc agcgatttct tttggtggtt catgggaaac agctaactgt gaagaagaaa
     2221 aaacgatagt tgctaattcg acattggcaa cggtcaaaag aagagaaaac aacaatccaa
     2281 atgtaaaaag aatgtattgg atatagttga acgcttctct taacgaagcg attttttcaa
     2341 ctaataaaag agaaatcaaa gagataccat atattccgct gaacaagaaa acgtacatct
     2401 ggaacaaata aagaaattgc tccttataat acataaaaat aaaaccacca atgattcctg
     2461 caattatgaa tgtaataatg attttctttt tccccaataa acaccacaat acttgatgta
     2521 atgaaaagtc attattcaac aataaactga tttctttatt catcaataag aaaaaggatg
     2581 ataacaaaag gaataaaaga atcaatccaa tagttaaata cactcgataa ttatatacgt
     2641 ctgtatttga aataaccgaa tacgaatagc tattttcaaa gtcttcaaaa atattagtgg
     2701 cataatcagt gtgaaatgct tgattgaatc gatcagtgaa tagtgaaatg aaccgttcat
     2761 aggcttcttt ttctctcgtc atcaagaaaa attcaccttc aaaatctttt attttgatcg
     2821 attcttcaat ggacgttacg cgaaaggagg tattagaata gggtaccttc tcgtgagaag
     2881 atttgacatc cccttgataa tacaatgtca tttcaagctt tggctgtatc ttgaagttcc
     2941 aagatgtatc tacttcattg gattcattta ctgttttttt catataagaa agctcagttt
     3001 ctgatgagac attttcaaat accatgatta gctgctcata ttcttcttgc ccaataaaat
     3061 gttgtggcaa tcgaatcgga gtataagtat ctgtttgatg gaaaaattca tttgtccgat
     3121 agagtacctg tttatttata ctaaccaagg caaaaccact catgataccg gtcactatga
     3181 ttgtgagtaa aactgtgaac ttttttttga ttatcaccac tctcccttac ttaaatgatt
     3241 ctttgataaa atcataccgt ttttcatcaa aaaaacgtat ctatcaagtg tataggtcat
     3301 gtagaataaa tctatatact gtagaatcga aaggagaaga agatgaacac cggagaaaaa
     3361 atacgaactt accgcagaaa ttgtaagctt acgcaaaaag aattaggcga aaaaattggt
     3421 gtttccgata aaacgatttc tagttgggaa aattctcgta caatgccaga ccttgaaatg
     3481 ctgtcacttt tacatcatac tttaggtctg ccgattgatt ttccttctat tgaatcagct
     3541 accgaatcaa tagaaccaac attgccagat gaacctcttg ttaacaagaa atcttattca
     3601 tcaaaacaac ccttctcact caaaaagaca ctatctttct ttctgctcgt cttttgtttg
     3661 gtctatcttt ttcttatcaa ttatcaatac aaaaatgaaa cgatcgatcg attcaatcct
     3721 tttttgaaac cacaaatcgg ctataccaca ctccctgtag gatacgtgga caattccatc
     3781 gaacgttggg tatgtaatga tatctttggc catggtacat ggctgtcttt tcacgctgga
     3841 gaggtagaaa aagagaaaaa ccatgctgta atcaaacaca aaggaaaaca cgtcatgaac
     3901 gttcgcctgc tcacttggga agccattccc tcagattacc aagaaatcct cagccaagac
     3961 tatgacgacg ccttaaaaag aagccctcag gagccagata ggcattaagt aggagatgaa
     4021 cgtagagata gaaaaaatca atgcacatga tcttatccaa aaaacagggg tacaaattaa
     4081 ttgaaaaagc cttgagatga aagttcctaa ataaaaaagt tcagaatgat aggtatttct
     4141 ggcttatagt ataatattta cgccacagcc tcccaatgat tctttttgga atcataatca
     4201 aggatggaca ttcacaaaaa tattttgctc attcgatccg aatagattaa cgaccaatct
     4261 agtaagtaat atagattggt acgtagtcaa gctgcacata atttagatca attttagttc
     4321 ttttttatat ttctatgatc tgctcattta cttttatatg atggcttaca gtaacataaa
     4381 taaatatgat aatcgctggt agtttatcca agagtactca ataaaataca aaatggattg
     4441 ttcaagcgcc tatcataatg ataaaatgaa acaaataaac gatacaagga ggaagagact
     4501 ttgagtaatg gcagaacaat tttttcattg taaaaattgt tcagttgtta atctatggga
     4561 tttcggtagc atgggcattt ttttatagag gaatcacacc aacctggccg ttttatctct
     4621 tgttagtggg aatattagta ggaaattttg cccctcttca ctatcgtacg aacttttttc
     4681 caactgattc tggccttttt cttaaaacaa agacgcgaaa attagaaaac attattgaaa
     4741 tgacaattac ctgtataatc attttcttag ttatattcct aaacgtcttc taataagaat
     4801 ctcttaaaat tagcttgtta cagttagtta cctagtttat ataacacagt tatcttatct
     4861 tccttatcaa catcttttgc caactctttg tcttaaattc gaaacatata agcagagcta
     4921 cgaacaccaa gactgtttcg gctctgtttt ttgcatcaaa ttcactctta tatagctgat
     4981 aatctcggct ctttaaaaga aattattttc gcttcatttt attataaaaa ggctaggaac
     5041 cttgatgtta tcaggttcct agcctttatt taagtattac cccacagacc cttccatata
     5101 gatttttaaa ttacacacta gtttaaacta aaacaaacaa ggaaaaactt accatttaat
     5161 caaaaaatta gctcatatga atatattaga atgtaaatta gactggtcaa aatctggtca
     5221 aaaaagagga cgaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt
     5281 ttattggatt attcccttgt tcgatataga ctcaaatcac tatatcacta gatatcaaac
     5341 ggcgtcatac ggagtcaaaa acatcaaatt tgacctgtta aatggtcatt gaataacatt
     5401 taaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa aaaaatatat
     5461 acagccctat aggtaaagta ccgcagggct gtatattttt tatttcagat tacctgaaat
     5521 gattccattt aatttttatc tcattttttc ctactagtta gtatcaaata ctcccctatt
     5581 ttctcaataa actattttgg attacatggt atctaaaaca gccaaaacct tgatattaca
     5641 gtaaaaaatc acgttgtttt cgtttcattt cagatacatt tcacttaagc ggattccgaa
     5701 aaaacaaaag aaaaaggaac ccctagttag cctatgcttt ctaattgttc ctcttgagat
     5761 acgatcatat aacaacgggg tggggtaatt aataaaaaga tggaaaaacc gttattcaat
     5821 aactttctta aatacttcat tataaaatgt gaacaagtaa aaagacatct atccctattt
     5881 tctacacttc cactttacta ccatctttga atcatacaat tttcttaact cttctcattt
     5941 acctcaattc attttcaagt ggaatcaact catcatctaa cattttacgc catgctcgct
     6001 tcatttcttg tgggtattta aatggcttcg cttctggatg tttggcttta tatccttcgt
     6061 aatccttact attgataatt gctttcatat taggaattgg atcttcacct ggcatatatt
     6121 gcagattaga agcatgtaat tctttctcag aaacaaacca ctcattggaa aagacatgaa
     6181 tcaaatcatc actcgcttgt gtaaaatagc gacgtttaat gacaaagata tcttcattac
     6241 tatctaaagt ccccacatca aacgcattta aaatttgtcg gtaaacttct ttgactcctt
     6301 ctgttttatt caatttagcc aaagcttttt caatttcttc tcgtgcatct gaactattcg
     6361 cagcataagt tcctagtaat tgatcaatat aagtagaatc aatatcatac aacttcgtgg
     6421 tattttcact ataaaattcg atcgttgaaa aatcttctcc ctctttttct ggttcttcct
     6481 ccatcaatga acccttcacg gtctcatata caccaatttg ttcttccaaa agttgaattt
     6541 gattattcaa ggttggagat ttcaccatgt catcattgta atcgtcataa gtcactaacg
     6601 attcatacgc acgattcaat tcttgaaatg ctttgacgta ctcgatacgg atttcaagtg
     6661 gcgtatgttc atcaatggat tccatggatg aaacctcttt taacttacca tatgcttgtt
     6721 tgaatctttt tttggattcc tgataacttg gataaatcaa acccgattct tctttagctt
     6781 ctgaatacag ttttgtcgca tcctcgacat tcttctccat tgtcgctggc tttcggaaag
     6841 taacaattag tccttttgtt ttttcaggat acgtacggtt cgtacgtgaa aaggcttgga
     6901 tcaatcctgc atactctaga ttacgatcca caaatagggt ttgaatcgta ggggcgtcaa
     6961 aacctgtcaa tagacgatcc actactatca ctaaatcgat ttgtttccca aattgtttga
     7021 attccgctct ttttcgtgcc aaacgattat tgatgtctcc gttataacgc tcaatgtctg
     7081 ctaatgacca ggcagtatca taatactgat tatattcctc aataattttt tgcatttctt
     7141 cttgttggac acttgaatct cggctgtttt cttctaatga ataggtaata gcgattcgtg
     7201 gaaaatcagg atcctccatc gttcgtcctt cacgaatggg ctgattggga aactcttttg
     7261 ttaaccagtc aggttctttc gtcatctctt tgatggcccg ataatacttt ttggccatgt
     7321 caatggaact cgtggttaag atcgcagact tcgttggacg gccatttcga aaatcaaatt
     7381 ttgtataggc attgtctgga cggaacattt tatgaatgac tttttggata tgttcctctg
     7441 cttcaaaaac agtagggtcc aaataacttt cttttttgac agactccatt tgatcgatca
     7501 tacgattgat ctgttccggt gaatactctg catatgtttc tacttctttt aatttccgat
     7561 agattttatt ctctaatgaa gtcggctcca cggtgttttc atgctctact tgaaatccta
     7621 aaacagagcc atcttctagc gcattcttga tggtataggt gtgcaagact tccccatact
     7681 gatcatgggt cgtacgtgcc aattgccctt tggcttgttt ccgattctca gggaaaatcg
     7741 gtgtacctgt aaagccaaac caagtggatt tcggaaacat ttttttgatt tcttccatat
     7801 tttcagcact taacgctcga tgacactcat ctactacaaa cacgatatgt tgccccatta
     7861 atttttggaa gcgattggtt ccttttttct cttcctgttt ctttgcatat ttcaacgccg
     7921 catctagttt ttgacgggtt gtaatgatta caacatttgc attggcatct gccaacaggg
     7981 tttcacttaa ctctttggca cttcctgttc ccacgatcaa gctattcgct ttggcgttcc
     8041 cggaagaaat cccagtatta aattccgaag caaatttcgt aaactctgtg gtggtctgat
     8101 tatctaaatc tttgcggtcc actaacatga tcgttcgatc gatccccgat tttcgtgcta
     8161 aaagcttagt agatacaaaa ctagtcaacg tctttcctga accagtcgca tgccacacat
     8221 accctgattg atgtttattt gcggcaataa acaaggcttg aatcgcatgg acttgataag
     8281 gatgtaacac catgagggtt ttattgtctt gatcttcact gacaatcgta taatccgcaa
     8341 tcaagcgatg ggcatccggg atatttagca cttgtttgca aaactcatat aagttttcta
     8401 cctttttatt atctttcgtt cgccaactaa ataaaaactt aggatgcaaa tcctttggta
     8461 aggcatttgc aaaataccga gtggtttgtt cattggaaac cacaaacaac tgtaaggtcg
     8521 aaaagatatt gttccgaaat atgccttctt ctgcatattt tttgatttgg ttaaacgcct
     8581 gataaaaacc atcttttgca gttacttgtt tcaactcgat ttgaacaatc ggtaagccat
     8641 tgatcaataa ggtgacatca aaacgtcgat cccgtgcttc tatgttactt ccacgttttg
     8701 caatttgatg gaccacttca taagtagaga ttcctccacc aatgtcttga ttggaataaa
     8761 ggataagtga gacagaaccc aattgcgaat cttcccgttc aatcgtgatc cgagccatcc
     8821 cattttcacc ttttaaccat ttcgcagcat caaagggggt tttcgttcgc agcagtaatt
     8881 ccgttttgat cgtttcaaat tctttatcgg tcaagggaga atcattcaac tctgcttgat
     8941 tatttgagat gattttttgg cgtaaattgt cccaaagatc ttcttctgat tttagatccg
     9001 gacgatacgt ccactgatta tgtccttccc ccagtacacg gatcaactgt tcttcgactt
     9061 ccgcttcctc acgatgacta attttcattt ttcttccctc ctagacaaac attttttgca
     9121 agaagccttt tttcgtttct tttagtaaat ctaacttacg ttggtgaaga gcgatcgtgt
     9181 cgtcgagttg tttgaagaag ttaccgattt tttgttgttc atttatatcc ggtggaaact
     9241 gaaatgtcct ttgttctata ccacctttag tcacatgtac cattgtcgtt ccgttagttg
     9301 attctttaat tttctcttta tcagtcaata gccaagtata tagatactgt ttgtccaatt
     9361 ccttagataa aaatttaagt ttccaaatat gataatggta gattacacgt tcttcattcc
     9421 acatttcagg accgaagctt gttgcccata aatataagag atctccttta ttagcatact
     9481 tgtcttcctc taattctaag tttgaataat accatctatc attagtatta aaattaccta
     9541 ctcttaaaac cctatatttt ccagaatcaa gtaattcttg ttgtttaaaa gctctaccat
     9601 tcaaaaaaac taccacttcc cccaacttcc gatcttccca atctcccgta aatcctggaa
     9661 aacgaatttc tggcactttt gctccgtttt tagggaacat tttttgtaag aatccttttt
     9721 tcgtttcctt cagcaaatct aacttacgct gatgaagagc gatcgtgtcg tcaagttgtt
     9781 tgaagaaggt gccgattttt tgttgttctt cctcactagg aaacattgct actatatttt
     9841 taaacttttt tagagacaga acatgttgac ctgttccctc tgcttgaata gataattgtc
     9901 gttggattcc attgttaata cgtcttaaga agaagtcgga atcagcagat tttaaagtaa
     9961 atacaggata aaaatagctt ataatccctc tatcaataat gtcattacgg ttaaacacaa
    10021 acacatcatt atcacttcga ctacggaacg tgaaatatcc tctaggtagt acaaagtaac
    10081 caatattatt ttctgtagtt acttgccgat ttgcaaaata gtcttcttgc aaaactatcc
    10141 ctttttgttg agatgaagtt agcataggaa attgattttg tacacttgtc ttttcaacat
    10201 aatctacaac gaagtccccc aacttcctct gttcccaatc atctgtaaat cctgggaaac
    10261 ggatttctgg ttgtgtatca ttgctcatgt ttgaacacct ccagcgcacc ttgtaaccac
    10321 gcttcatttt caggtgttgt ttgcagggaa gagatagctt ctaaaagttt tttttctagc
    10381 acttgctgtt cttgtcgtat cttcttgatg tcatttccga catgaaccat atcaattggt
    10441 tcttcttctt cgaaagtatc tacatagcgt gggatattta agttatagtc attttctttg
    10501 atttcatcaa aggttgccaa atgagcgtat ttctcgacat cttttctttc agcgtaggtt
    10561 tcgaggattt tttgaatgtt ttcttccgat agtttatttt gatttttccc tttaacaaat
    10621 tcacgactag catcaatgaa taatacatct cgagtttgac gattcttctt caacacaatc
    10681 accgtcgttg gaatcgatgt cccaaagaac aagttcgcag gcataccgat cacagcataa
    10741 atactgccat cttctagtaa tttttgacgg atgacccctt ctgcagcgcc acggaataaa
    10801 actccgtgtg gtaagacgat ggccatggta cctgtttcct tcaaatgata gaacccatga
    10861 agaagaaacg caaaatctgc tttggatttt ggcgctaatt tcccataacg attaaaccga
    10921 gaatcatcta agaaagtcgt atctgctgac caattagccg aataaggtgg gttcattact
    10981 actgcatcaa atgtgtaagg ttcatctgtt ggccagtcct tattcaacgt atccccattg
    11041 cggagattca tttcttcggc gtcgacacca tgtaaaatca agttcatttt tgctagattg
    11101 tatgtcgttg tatttagttc ttgcccatga tatttaacgt tatctgggtg tgttaagtag
    11161 ttacgtacgt ttaacatcaa tgaacctgaa cccatcgttg gatcaaaaac actaaagaat
    11221 cgtcgttcct tttgatcgag cgttacgatt tgcgccatca tatcagaaac catatgaggt
    11281 gtgtaaaatt ctccggcttt cttccctgct tctgaagcaa attgactgat cagaaactca
    11341 tacgcatccc cgatcacgtc cccatcgtgt tctaaaacat ctacatcatt caatttcttg
    11401 atgacttcgg taatcgtcac atttcgttgt tgctcatctg ttcctagttt ttttgattgg
    11461 agatccacat catcaaataa cccattaaat tgattgtagg tagatgccaa ttgcacaaag
    11521 gctttgttta gatcgttcaa ttggaacgtt gcttgttttg cttgatccgc taagacgttg
    11581 aaaagatact ctggtgcaat tgcatatccc aaaatatcaa cgattgtggc aatcagatct
    11641 tcttttgatt cttcatctga aagtaattca cgatacaaca ttgtttgttt gcttactgtg
    11701 tcatattcct ctaaggattc atctgctaaa agaaccactt gttccaacaa tcgatcggat
    11761 aaatatttat agaaaatcag tcccaataaa taatttttat attctgacgc atccatttta
    11821 ctacggagat tatctgccgc actaaataat ttttgattta attctgcacc caaaaagata
    11881 cactcctatc tcttatttaa agttgctata taccctctta ttttagcata ccccctttta
    11941 taaaaagcaa aaaaaaaaga aagaaactta ttcttgctaa taaactacgc gaaaggagtc
    12001 taacgttgtt tgatataact tagactgatc gttaacttat tttttatatt tctacatagt
    12061 tatctttaga accatttcag atacatatga aacaattaca tatgattttt tcataaaaaa
    12121 acagtactgt ctagtagtat aaaatataca aatttcttaa aaattttttc actaaaatca
    12181 ctacctgaaa cagtctaaaa cacttatata tcaacgttta atgaaactat ctccgtttca
    12241 tttcagatac aaataaatat agtcgggctc caaatccgaa aaaaaatacc cccagtagct
    12301 tatcctaagc tactggagat gtataagtac ggtcatataa caacggggta gggtaaataa
    12361 atgaaaaaga tggaagaatc attattcaat aactttttta aatacttcgt tgtaatcagt
    12421 tacctgtccg ttcttaaata ccacagaata atcttttttc ccattttcaa gtaaccgaag
    12481 tggaatatct ttaccaactt gctctgtcac tgcattactg atacctgtta gattagctaa
    12541 taaatctgat aaagattgag catctgtaga aatctctgta ttagtattta tcgtgattcc
    12601 tttatcttca tttacaagtt tccaagtagg tggtatagct gtgtatgttt cgatgaatga
    12661 atcaattctt tcatctatcg tcttcccagt atctacttct gtctcattac tcttagatga
    12721 atcgattctt tcatccatcg tctgctccgt aactgcttct gtctcattat tctcaccgga
    12781 aactctcttc acacccaaac ttatatattg tccatcttta gtgtgcatag ttaaaattcc
    12841 cacgctttta ctaataaatt cactataacc agttctttca atagagactt caatgtattt
    12901 cacactatca tactcaaaag aaaaatagac atgtaaaagc attttgttgt ttacatctac
    12961 ataataatcc tttgactcta cttgagacct tcctatacgg aatacagctt tactgtctga
    13021 tatctctata ccagcatcct tattattaat ctgccaatct ccaagtagct cttctggcaa
    13081 gctagtagtt tcttgtgaac actttaccac ttcactggta gaggtcgaaa cattcacctc
    13141 cgcactgtta gaagaatttt ccaaggaatc aggagcctta gcacaaccaa caagtcttta
    13201 tatattgtgc agccgatatt ttcttcattc agtacaccct tgaaatatgc agtgttagat
    13261 aaagcagttc gtcctgattt gctgaggcac ctatctcttc ttgaacgtac tccttgattt
    13321 tcaaggccgc ccgatactct ttcggaaaac gctgcttcac tgaagccagc aaaaaatcat
    13381 ccttctccgg caactcttcc ttcttaatca ttcgggcaat aaaaaactgt aaatgcgtca
    13441 caaatcttaa gtaaagcatc gaatctttat caaccttttt ttcgggaaac agatatccta
    13501 gcatagccaa gatatccttt agtgctctta ccgagagcat ggtttcttcc atatttgctt
    13561 gttcactttg ggcatttaca atgtgaaacg caatgtttcc agcctcctct tctggcaact
    13621 gaacattcat ttttttgttg atcaattgga tagcatagca gccgatctca aattcttttg
    13681 ggtaatactt ttgaatttca atcagcaggc gattttgaaa aacaatgcct ttttgactgc
    13741 gttcaatggc atgcttcaag tgatcaacca aggtaaaaaa tagactttta ttcagcttaa
    13801 agtcaaactt ggcgttggca taatcgataa ttcgcttgac gcaaataatt agatcatccg
    13861 gagcagcctc aaacagttta atgtaatcct tttttagagc atcagaaagt gaatctaatt
    13921 taaatacttt ttggattttg tcagccggaa ccaaatcgcc tttctttagt tgaaatccaa
    13981 tccctttccc catcaaaatt acttctttgc cttgcttatc taagcaaaga attaaactgt
    14041 tgtttaacgt tttaattact ctcattagat tcaccgttct ctctaagcta agccatttct
    14101 tgcgattact ttttgatacc aaaagaagct ttcttttttt attcgtttta attctttaag
    14161 attctcatcg gttcggtcaa catatataaa accataacgc ttattgaagc cttgatgggt
    14221 actaacaaca tcaatcgctg accaaggtaa ataaccaaaa acatctacac catctgttaa
    14281 agctgcttga atagccagaa tatgtttggc tagataatca attcgatcct ggtcattaat
    14341 tcgtctatct tcctcaacta tgtcgggtgc cccatagcca ttttcagtaa ttaaaatagg
    14401 taaatcatag cgatcgtaca atttcctcaa tgttaatcgt agtccagtag ggtcaactac
    14461 ccagccatat ggcgttttat ctacataagg attttcagct gcccggtaga caccttcttc
    14521 tcccaacatg atctgttgat cccccgctct agcggaaaca tctgatccgt catttttgct
    14581 ggcagcgatg gtggcagttg aataataatt aatcgcaata aaatcgggtt taccggagga
    14641 taaaattgcc tgatcctctg cctcaatttt aggatataat ccacgatcat tcaaatagtt
    14701 ttcaaacaaa taattgtatt ttccccgaac tgctacatct aagaaagacc agcctctcag
    14761 tgtttcccaa ttatgggctg caattgcatc ttctggactg gaggtagctt gatacatagc
    14821 cgttaaattg attgctggac cgatttttcc tttaagattc aactgatgat acaagtgaat
    14881 tactctagct tgagctaata aaacatggtg attaatttga aagagttctt tttttgaagg
    14941 cagctctcca cttggtggca aaccaatcgc tccaggatga aggatcatcg tgttttgctc
    15001 attaattgtc agccaatagt tcaccttgtc accatactca gtaagcaata cctgtacata
    15061 gtccacaaaa taatcgatag ttgctcgatt taaccaaccg ccctgctcct ctagaaaata
    15121 aggtaaatcg aaatggtaca tggtgacaat cggttcgatt ccctgattca ggcattcatc
    15181 aattacttga tgataaaaag aaattccctt ttgattggtt ttattatttt caatatccat
    15241 aattcgcgtc caagcgatgg aaaagcgaaa agcttttaag cctaattctt taaacagctg
    15301 tatatcttct ttatagtgat ggtaaaaatc cgaggcaact tcaaaattag ctaccccttc
    15361 tgtatgctga tacttgtcaa taatagacgg ttgtttccca tcctcctgat aggcaccctc
    15421 tgcctggtag gcactaatgg aggcacccca taaaaacttc tctggaaatg ctgaaagctg
    15481 tttgtattgc acaaaaatcc tctccttaac taatttgcat caatggttcg tgttccttta
    15541 agcttccgct tgcttcacta attcctgcgt aattttcact gttggtcact accacaatca
    15601 ctgtatcatc gtagccagcg tttctaatgg cagcgaaatc ggcgttgatt aataattgtc
    15661 ctgctgacac ctgatctcct gcttttacaa atacttcaaa gggttcccct tttaaattca
    15721 cggtgtcgat ccccacatgg atcaataatt caataccttc tttagaacgt agaccaatcg
    15781 catgtttaga ttctaaaata gtaatgactt ctccctcaac aggtgaataa atgctgtttt
    15841 cttctggatg aatggctacg ccctttccca atagtccctt agaaaagaca gcatcgttca
    15901 cttcagaaat aggacacacg gttcctttta ccggattttc aacaatgact gcttcggcta
    15961 ttgccgtttg ctctgattca tcagaagtat cgtcaaatcc aattagataa gcaatgataa
    16021 aggttgcaac aaaggcgatt acacacgtaa taattgcgtg aacaatattc attggatttt
    16081 ctccaataaa ggctggtaag gctgctaagc caggggaaac aaaggcatat ctgactaaac
    16141 cgctcaagcc agcatacaaa ccagcaattg aaccaccaat catggaagca actaatggtt
    16201 ttttcagctt caaggttact ccatagagtg aaggctcagt aattcccatt aaagcagtga
    16261 tcccagtgga cacagctagc tgtttcaact ctttgttttt agttttcgcg gctacagcaa
    16321 aggtagcacc tgattgagca atattagaag ccagcattcc tggcccattg atcatttcag
    16381 aacccgtact gctcaattgc atagtagcga ttggcgtcat tgcccaagct gtacccgtaa
    16441 ccaccaaaaa tggctgcaaa ccacccatca aaaatggaat taaccaagct gctttgccgt
    16501 taatccattc agcccccatt gctataagat cgttcagcaa cgttccaaac ggtccaatga
    16561 caaccaacgc taaaggcccc ataattaaaa ataccagcat cggcttagta aagaatttaa
    16621 taaacgaagg cgaaattcga tccgcaaagg gctctacata ggacatgatc caaacagtaa
    16681 agataatcgg taaaactgat cccgcataat ctgcagctaa taccggaatt cctagaaaag
    16741 aaacggcatc accagtagaa aaaagctgtg aaatatttgg atgaagcaaa atgccagcaa
    16801 cagtaatcgc caaaattggg ttgacatcaa actttatggc tgccccatag gctaagagta
    16861 ctggcataaa ataaaaggct gcatcagcaa tagtattcaa aatgatgtaa gtttgactac
    16921 tgtctgatag tacaccagtc aaagtcaaga cggccaaaat ggcttttacc atcccggcac
    16981 ctgttatagc tggaatcatc ggtgtaaagg tggtagaaat gacactaatc aatcttgaaa
    17041 taatactttc ttgattgtct gaagaggggc cctttttaat tgaagttccc acttcctttt
    17101 gaatttcctt gaaggctgtt tggacttcat tgccaatcac cacttggtat tgtccaccgc
    17161 tatccaccac actaattaca ccaagtgttt tttctaaggc tttcgtatcg gctttccttt
    17221 tatctttgag ttcaaaacgc agtctggtgg cacaatgggt taagctgacc acattttctt
    17281 ttcccccaac ctgttgcaat acatttcttc ctacttctct gtaatccatt attctctctc
    17341 cttaaagcag taaaaaagac caagtcaaac cacgccccaa tcaacattga agtgttagtt
    17401 tgtcttggtc ttgcctgcat aatcagtaac atgccaataa cgttattttg ctgtaatcca
    17461 ataatagcat attatgatag cgcaatcaac agggaattta attttttatc ttttcgtttg
    17521 accgtatagg gtaatataac agttagatcc catcgactaa ggtatatctg cgtatactta
    17581 ctgctaaaat aagtatatct aatattaact ataccagtaa aaccattcct acataaccag
    17641 cgggaaattc ccaaaatcgt gaaagcatca aaaatgcata taacggatca cacaacttca
    17701 acaattctgc tcttgggaaa aattgatgaa tttggtgatt aaaggatgga ataaacagca
    17761 ttccaacaat ataggcaaca atagtgatac ttgttttttt ggtaaaaatc agtaagcaat
    17821 agccaatttc aatcattccg agatataaag gtatcgatag aatgatttgg gctagtattc
    17881 ttaaaaatta actagcaaat gtttaaactg atttatttct aatctacatg tagtaagtat
    17941 ttcaattcca ccaattatca ataaaaatac caaacatatc cataataatt ttttcttttt
    18001 catttctttt atattgttat aacagtgaat aacataaaaa ttcccgacaa tcattgtaat
    18061 attttttttg tcacctgtat tagtatttaa tttataggaa actataaaaa ctccctagtg
    18121 aatttacacc tttgggagtt cctgtttgga cggtatgcat aatacattta aatcaattta
    18181 acattaacac ctcagtatat ggtatctcta catatacacg gtcttttttt ggatagtact
    18241 cgacatttat attgatagca cttccattgt ctaatatagc tttagcccgg tatgtgttat
    18301 ctccattttc atgagtgatt gtcacatcat cacatgtccg atttaaactg tactgttctt
    18361 gtaaaatctg tgttaccaat ggtttcgatg acttctctaa tccagatgta cctgtcattt
    18421 ttgaaaaaat gatacctata atagccaaga caacgataac tataatgata aacttcttgt
    18481 tcatatttac tttattcaac tttttatctc ctatctccaa aataatttgc tcttatccct
    18541 cttatcagta cattgacatc cctaaaagta caccaaagat tgctccagct acccctgcta
    18601 tcatcaaaat cgtacccatt tgttcatctt tatctcgata taagtagccc ataataacag
    18661 caacagcacc aaatacaaca ggaataaatg ctaacgctac taccatagaa atccaaccaa
    18721 taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc atttcattaa
    18781 ttgtctgctc agtacttttc tttactgcgt ctgctccagt tgtctcatct gtttcttgta
    18841 gtgctccgca aaactggcaa tacttacttt catctgttat ttctttgcca cattttctac
    18901 aatacatgtc ttctcctcct aaaaacattc aattgtttat tagttaactg tttactttat
    18961 taaatacatc agaaaacagc tcattcattg gtacacttaa tatctcagaa agcatcttca
    19021 tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat tgctgtgtaa
    19081 cattcatttt tttgctaact ccgtttgaga aagtcctttt tcttttctgt atcggctgag
    19141 attacttact tttttcatga ttctcccctc ctgttttatt atatacaaca atatgatgta
    19201 tttcaactca taaaatataa aaaaacttca aataccatta caaatacaac aacttgttgt
    19261 actatactga gatgggggtg tattaatgaa acagaaacaa tatgcaaagg tcattagaga
    19321 aaagcgaaaa gctctcgggt ggacacaaaa agaattagct gaaaaaatct tctctacaca
    19381 acaggcagta gcaagatggg aaaattctgt aacagagcct aacctcgata gcttaaccgc
    19441 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg tcgtagatta
    19501 tgaggaagag tttttggctc tctatcgttc tcttagcact gaagatgcag ttcgaacaat
    19561 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
    19621 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
    19681 gctatggata acctgtctag tttaatacaa ttgggtcttt tctcttcctt actctccgtc
    19741 catcatctct tgttacactt gtaaattgat aaagaggaac taattcaact cctgataata
    19801 tcaattcttt tattacttca tctatccctg ctccttttgc taggtagact aaaaaactac
    19861 tacttgcttt cacattgtat agtctcttaa tatccttaga agctcgttca agagtgaatc
    19921 cttgtttaac aaagtagcct ctgttttctt ttaaagcatt ttccacgctg ttattcccaa
    19981 cattacgtag acgttcacaa acagtgttag taagttcttt ctctgtcatt agatatgttc
    20041 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
    20101 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
    20161 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
    20221 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
    20281 agacattgct tctcttatga ttaaagtttc ctaacgcttt ctcttccttt aacctattta
    20341 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
    20401 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaaa
    20461 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
    20521 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
    20581 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
    20641 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
    20701 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
    20761 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
    20821 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
    20881 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
    20941 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
    21001 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
    21061 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
    21121 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
    21181 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
    21241 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
    21301 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
    21361 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
    21421 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
    21481 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
    21541 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
    21601 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tctttatcta
    21661 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
    21721 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
    21781 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
    21841 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
    21901 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
    21961 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
    22021 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    22081 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    22141 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    22201 cataatacct cgataaaaaa gaggtgtcaa tatctttgta aaatttattt acaacacccc
    22261 tttttcgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    22321 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    22381 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaaa
    22441 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    22501 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    22561 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    22621 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    22681 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    22741 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    22801 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    22861 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    22921 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    22981 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    23041 tactccttgt aaactaagag gagatgattt catggcaaaa atatcaaagt acaaaaagaa
    23101 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    23161 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    23221 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    23281 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    23341 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    23401 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    23461 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    23521 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    23581 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    23641 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    23701 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    23761 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    23821 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    23881 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    23941 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    24001 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    24061 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    24121 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    24181 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    24241 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    24301 taacaggttt acccaacact gccttccatc tcataactga tcaatcgatt gagttcgact
    24361 gcatattcca ttggaagttc tttggtgaat ggttcaacaa agcccatgac gatcatttca
    24421 gttgcttcag attcggtcag gcctcggctc atcagatagt agagttgttc ttctgagatt
    24481 tttgagactt tggcttcgtg ttctaaagag acttggctgt tgtggatctc attgaatggg
    24541 atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt cacattcgat atgagagatc
    24601 gaacccgcac tgtttttggc aaaggttact tgtcctcgat agtttacttc tccgccgtct
    24661 tttgaaattg atttagagac gatagagcta gatgtatttg gtgcattgtg gatcattttt
    24721 gcacccgtat cttggatttg gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt
    24781 gcaccttttc catctaagta aacacttggg tatttcatcg ttgtttttgc acctaggttt
    24841 ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg ctcgtttggt tactaagttg
    24901 tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta
    24961 aagatttcta cgatggcggc atgcaggctg ttacttgaat aagtaggtgc cgtacaacct
    25021 tcgacatagt ggatgcttgc tccttcgtca acaatgatca gcgtacgttc gaattgcccc
    25081 gtgttttccg cattgatccg gaagtacgtt tgtaatggaa catcgacttt gacgcctttt
    25141 ggcacgtaaa taaaggtccc acctgaccat acggctgaat tcagcgctgc taatttgttg
    25201 tcggttggcg gtacaagttt tgaaaagtac tctttgaata attcagggta ttctttcaaa
    25261 gcagagtcag tgtcagtaaa gacgattcct aacttttcga attcatcttt catattatgg
    25321 tacacgactt ctgattcata ttgtgcggaa gcaccggcta gataagctcg ttcagcttct
    25381 ggtataccaa tcttttcaaa tgtatctttg attttttctg gtacgtcttc ccagtcacga
    25441 gcgggtttgt cacttggttt ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg
    25501 tcggggcccc atgtttgcat tggcattttg ttaaatgttt ctagagattt cagacggaat
    25561 tcaagcatcc attctggttc gcctttgatt cttgacatct cacggatcac ttcttctgtc
    25621 aagccttctc ctgtactgaa aaccggttcg acatcatcgt gaaacccgaa tttatattct
    25681 tctaattctg gtacgcccat gttctcactc ctcttccttg tggtaatgat ggaaagctgc
    25741 ggtaccatcg ttttccattg cttttcctag tgctttccag gcaagtgtcg cacatttgat
    25801 ccgagcggga aatttagcta caccaccaag catagcagca tcgcctaatt ggtcgggatc
    25861 tttgacttct tttccttgga caagctgtag aaagtctaca gttaaatgtt ctgcttcttc
    25921 tattgatttt ccgatgacgg cgtctgtcat catcgaggca cttgccgtac tgatggagca
    25981 gccactgccg tcaaaggcga tatttttgat gattccgtct tttacatcga cttgcaattc
    26041 gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct
    26101 tccacgatga tgcggatggg aagaatgatc caagatcact tgacggtata aattgtctaa
    26161 tttagatagt cccatgttgg aaaaactcct ttgttgccat gattgcttca actaaacggt
    26221 cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg agcagtcgct gatacttcaa
    26281 ggtacttcaa tagcggttgc gcacaatgat gacctgctct gacggctacc ccttccatgt
    26341 ctaaagctgt cgcgacatca tggggatgta acccatccaa attgaatgca acgactcctg
    26401 tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc atcaattgct tgtaattttg
    26461 gcaacacata agcggctagt tcttcttcat atcgatggat attgtccata ccgagttttt
    26521 gcaaataatc gattgcatgg cctaatgcga tagcgccggc gatatttggt gtccctgctt
    26581 cgaatttcca aggtagttct ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt
    26641 cgccaccaaa ttcaacaggt tccatttctt ctaaccattt tcgtttacca tataaaacac
    26701 caatacctgt tggtccgcac attttgtgtc cgctgaaagc aaagaaatca cagtctagtg
    26761 cttggacatc aatggccatg tgcggggcag attgagcacc atctactacg atgaccccgc
    26821 cgttttcatg gacaagttca gctaattctt gaacaggatt gaagacacct aagacattgg
    26881 atacatgagc aatggagacg attttggttt tgtccgtaat ctttttcgct gcatcctcca
    26941 tatccaggaa gccttcttct gttagttcga tatatttcaa gacagcacct gttcgttttg
    27001 ccaactgctg ccacgggata acattagaat gatgttccat gtaagagagc actatctcgt
    27061 ctcctgcttt gatatagcgg tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg
    27121 taccacgagt aaacagcact tctgctgttt cttttgcatg gatgaacgcc cgtacttttt
    27181 ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa
    27241 cattggcgtt atcgtgttcg taatagtacg ctaatgcctg gagtacttgt tttggctttt
    27301 gggtcgtcgc tgcattatcc agataaacta aaggttcatc attgacgtct tgaaataaga
    27361 taggaaaatc attgcgtagc tttttagcat cgatcatcca ttcaacttcc cttcgattac
    27421 ttcgactaat tctttccgaa cttgttctac agggattgct gttaagacag aaccgaggaa
    27481 tcctcgaatc actaagcgct ctgcttcttc tttatgcaat cctctactca tcagatagta
    27541 catttcttct ggatcaactc gtcctacact ggcagcatgt ccagcagtta cttcgttttc
    27601 atcgatcaaa agaataggat tcgcatcacc acgtgcttta tcagaaagca tcaagacacg
    27661 actttcttgt tgggcatctg caccttttgc ccctttcaag atgtggccga taccattaaa
    27721 ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg
    27781 ggctttattg gttactcgtg tatcgattcc ttggatttgt ctgcccgagc tgattgccac
    27841 gattttgact tctgcgtgtg caccttctcc tgctaaatct gagtcaaagt cagcgatcac
    27901 atgaccgtca ttcatgacac caattgccca gtcgacagaa gcatctcgta aaatgtgccc
    27961 acggcgattc atataagaag taatattttc tcctaattga tctacggctg aatatttgat
    28021 ttttgaacca gctttagcga tgacttccac gatgatatta cctgatgatt ttgctacttg
    28081 ttctttggtt gtctggaaac gttccagata agaaaattca ctatgttcat ctgccacgat
    28141 caacacatgc ttgaagaagt gctcatcgga tgcgccatct tgaatgaata aggactcgag
    28201 tggttcatcg atcacgacat ttttaggcac atacaggaaa ataccgctgt tcataaaagc
    28261 tacatggagt gcagtcaatt ggtcttcgtt catgtttact gcttttttca tataatattc
    28321 ttggactagt tctggatatt cgatcattgc agtgaacaag tcggtaaaaa tgactccttt
    28381 ttctgctaat tccacaggca gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac
    28441 aggattgtct ttcattgcat caaatgccgg aatcgtgcct gtttcactga tggtttgtgt
    28501 ttctttcaca tcaaataacg accagcgatg gaatttcacc cgatcgatat gcggcaatgg
    28561 cagttcatct gctttcgcta gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc
    28621 tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg agccagtttt tttctttcat
    28681 tcttgctccc ccttacgctt cttcttcttt atagtcgatt cctaattctt tactgatacc
    28741 agcgtagcct tctgcttcca gacgtttagc taggtcagca ttccctgtca tgactactcg
    28801 gccttccatc atgatgtgaa cgacatcagg tgtgatatag ttcaataatc gttgatagtg
    28861 ggtgatgatc aatgcaccga aattgtctcc gcgcatttca tttactcctt tagcaacgac
    28921 tttcaaagca tcgatatcca gacctgaatc gatttcgtct aaaattgcaa atgtaggttc
    28981 taacatcaac aattgcagga tctcattccg tttcttttct ccgccagaaa aaccttcgtt
    29041 cagataacgt tcagccattt cttctggcat atttagtaaa gccatttttt catctaactt
    29101 tttcaaaaat gccataacag aaattttgtc gttttcatca cgtttcgcat tgatcgctgc
    29161 acgcatgaat tccgcattcg tgatacctgg tatctcactt ggatattgca tagctaaaaa
    29221 taagccaagt cgcgcacgtt catctacttc caagtctaaa acatttttcc cgtcaaacaa
    29281 aatttcgcct tctgttactt catagtttgg attgcccatg atagcggcag ataaggtaga
    29341 ttttcctgtg ccgttaggtc ccatgatggc atggatttct ccggttttca ttgttaggtt
    29401 tacgccttta aggatttctt tttcctcgat cgacacatgt agatttttta tttctaagac
    29461 agacatgcat tataccccca aattctcttt cgttctcact cattttagac taattgagaa
    29521 tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt tatttattat taaacaattt
    29581 tgatttctaa attagaatag gtataaaaaa gatgagaaat aagccattac agacttattt
    29641 ctcatctttt ttgttccata ccttattttg catcagcctt tactggttta acagagccgc
    29701 cccatttgtc tgtgatccat tcttggactt ctttgcggtg aagcacttca atcagttttt
    29761 tgattttgtc actgtcttca tcacctttac gagtcgcaat aatattcacg taaggagagt
    29821 tgtccttttc aagcaatacg gcatcttcta atggattcaa ccctgcgccg taagcgaagt
    29881 ttgcgttgat tgcaactagg tcaccttcat cattttggta cgtagaagct aaaagtgatg
    29941 ggtcgatcgt atggttgaac ttcaagttct tagggttttc ttcaatatca tcgaatgttg
    30001 ctgtttccag atctactcca tctttgactt tgactaagcc agcatcttgt agaattgtga
    30061 tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat tgttgcacca tcttttaatt
    30121 cggaaacatc tttgactttt ttagagtaca agcccattgg ttcgatgtgg acagcaccgg
    30181 cattgacaaa gtcatatcct ttttctttga tttctttgtt caaataagga atatgctgga
    30241 agtaattggc atcaatgtcg ccttcttcca aagattggtt cggtaataca tagtcatcga
    30301 atttgacgat ttcaagatcg attccttcat ctttcaataa tggtttcaca tgttccaaaa
    30361 tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg
    30421 ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg
    30481 ctgctgcaaa tccaaaaatt ttctttttca tatcctacat ccccctatat cctattatct
    30541 tttgtctgtt ttcttagtta agaaatcacc gattccttga acgataaata cgattagtaa
    30601 aataattaaa gtcgcaacga atgtcactgt tagattacca cgctggtagc cttcctgcca
    30661 agcaagacct ccaagtccac ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat
    30721 cgagatcgtt gtaactgtta atccagaaat caatgcggga atactttcag gtatcaagac
    30781 cttccagatg atttcccagt aacttgctcc cattgcatct gctgcttcca gtacaccagg
    30841 gctgacttca cgaaaagcaa tctctactag acgggcataa aatggtgctg cggataaaac
    30901 aagagctgga atggctgctt gcgcacctag catagtgcct acgattgctt tagtaaatgg
    30961 aatgatcaaa accatcagga tcataaatgg cgttgaccgg aaaatattac tgatgatcga
    31021 tacgattcca taaatgattc gagcatacgg tttgtttttg cgtccaatag agtaaaggat
    31081 caatcccaaa actaatccga tgatcgtcac taagaccatt gagattaatg tcatatatag
    31141 tgtatcaagg atagcctgat tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt
    31201 ttctgaaaag cttttatcca cgatggatca cctcaattcc tactccttgt tctttgatga
    31261 acacttctgc ttgatctaat tctttggttt caccagtcat caagacagtc aatgaaccaa
    31321 aggaaccttc tttcacttgt ttgatctttc catacacaac gttgacatcg atgttatagc
    31381 gtcgaatcgc ttgggaaatg actggctcgt tggcatttct ttcgctaaag gtcaaagttg
    31441 ccaaacggcc gcttggattt tctttgatga gttcagctaa tagttctgtc gaatcagctt
    31501 ctggttcgat gtcttgttgt acaaagcgtt tggttacttc ttttttcggt tgtctgaaga
    31561 cagtcaatac gtctccttct tctacgactt tccccaactc catcacagcg actttgttgc
    31621 agattttgcg gatcacattc atttcatgtg tgatcaagac gatggtcaaa ttcaatttct
    31681 tattgatcgc taacaataag tctaatactt cttctgttgt ttgcgggtcc aatgcgctag
    31741 tagcctcatc acaaagcagg atctcaggat catttgccaa tgctcgtgcg ataccgacgc
    31801 gttgtttctg tccgccggaa agttgtgaag gatatgcttg tccgcgtcct tctaacccga
    31861 ctaaacgcaa cagttcttct gcccgttctt tacgtttgct ctttggtacg ccagctaatt
    31921 ccagcggcag ctggatattt tcaagtacag ttcttgacca taacaggttg aaatgctgga
    31981 agatcatacc gattttcttt cggaatgtac gtaattcttt gttttttaat tttgtaatat
    32041 cttgatcgtt tacgatcact tcgccgctcg tgggaagctc aagtccattc aggagacgga
    32101 ctaatgtact ttttcctgcg ccagaatagc cgacgattcc ataaatatcc cctttttcaa
    32161 cgtttagtga aacgtcattg acggcttgga tgtttccgtt tttcccattg aatgtctttt
    32221 tgacattcgt tagttggatt aatgacatgc cattcacatc tttctcttat aatttttcaa
    32281 acaaaaaagc cttcgccctc ttgccttaag caaaaggacg aaagcttgaa cttccgtgtt
    32341 accaccttga tttaccgtta cttcgcaata acagcctctt ccagtacttg gacttagctt
    32401 ctttccgtat actgtcgcgc tgtaacgggc actcccgtag taagtttgct tacgctcgct
    32461 tactctgctc taagaccatc ttccatctca ttttcgttac ccattttcag caaacagggc
    32521 tctcttcaaa cgtccgtgac atgtactctt cttttcaaag ctttctcgtt tcatatagga
    32581 ttgcttatga ttatagcaac tggaagaatc agtgtcaact tttttcaagt gattttctga
    32641 ttttataatt cgtcaaattc ttttggatca acatctttga aacttaagat ccacgcattc
    32701 atttcatctg aatcattcaa gatattgata tcttcaccga ttttatcatt aacagaagaa
    32761 actgtacccg ttagcgggct ggcaaattca ttgaccgctt tttccgcttc aacttcgatc
    32821 agaggttcat ctttttttag cgattgtcct gcttttggca gattggcaaa cgtgatgtct
    32881 ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt attcttttcc attaaataag
    32941 atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca ttttatatca gttctccttc
    33001 ataaattttt tcattgaatc caattgcaac aagctggtcc tctcgtaaga tcagtggtcg
    33061 cttgatcagc ataccatctg tcgataagac ttggctcgct tttgaagccg taaactcgcc
    33121 tacttgatct ttcagtccaa gttcccgata tttcatcccg cttgtgttga acaggcgacg
    33181 gattggtact tgactcgttt ctagccaagt ctcaatcgtt gaggccttcg gtacttcttt
    33241 gatcatatca acggtttgat aactaacgcc atgctggtct aaccacgctt tggctttttt
    33301 gcatgttgaa catttcgggt accagtaaaa ggtgtacaat tttcttacct ccttgaagat
    33361 cttgcaggtg cttcattttg gtatctcatc gataatatca acccgatacc gatcatgttc
    33421 cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg ggatccctgt taaaggaagt
    33481 aatccgatat ttgctccaat attctcaaag acatggaaca gcagcatcat gatcaaaccg
    33541 cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac acacccgaat catacgatag
    33601 attaaaataa aatacaagaa aatgacgaat gcaccaccga taaagccgaa gttttcaccg
    33661 ataacggtaa aaatcatatc ggactcacga acaggcacat agatattgct tacgttgaat
    33721 cctttaccaa acaagccacc ggtaccaatt gccaaaagtc cttgggccgg ctgataactc
    33781 attcctgacg tatcatggaa agggtccagc catgaatcaa tacgtgcaaa ctgataagat
    33841 ttgaatccaa ctttataaag caagtctctt ccgccttcag tcgtaaccaa gaagatcgtt
    33901 cctgctccaa cgactactgc caagattact acaggtgcga tgatgcgcca agagattcca
    33961 gacatcagga aaatcccgcc aaagatcgca agaaagacaa gcatcgttcc aaagtcatct
    34021 tgggccatga tcaatgctaa aaccggtatt gtcacgatca agagcttccc aatcagccaa
    34081 aagtccgatt tcatcgtccg ttcttttact tgcgtattat gtttagttac gatcagtgcc
    34141 atcatcaaga tgtacgcaat cttcatcaac tctgctggct ggaaagtaaa cgcaccgaat
    34201 cgaaaccagt ttttagaccc tgttgaagca gctaaattct gatcatagaa tttgagcaag
    34261 agtcccatta ccactaaccc caaaccataa aggtaaggag tcagtttcca gatccatttg
    34321 gaattcaaat gcatgatgac aacgattgct gccgctccaa ctaaatacca gacaacttgc
    34381 atccctacgc ctttcaagac tgctggattg ttcggatcat ggctaagtgc tacatataat
    34441 gagagcagac caatcaaaca taacagaaag actggtaaaa tcacgccata atcaatacga
    34501 ttatcgttcg aagcttttaa ttttttttcc atgtttcatc ccttttctta aaaaccatac
    34561 tgctgattat tatagcggtc cagttagata atggaaagtc tttccataga catttgggaa
    34621 aaattaactt tccgtttgtg cagttgcttg agcaaatgca gtacaaaagc ctactgctta
    34681 tctttagtgt atcatagaac tttttttgat acatgcaatt atctaccagc tgagattctc
    34741 ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg atctcttcgg caatctctag
    34801 cagctgatca gaaaccagat tggttcgttg gatgaaataa aaatatcgat ggaaattcaa
    34861 cggagtcatt ggcacatttt ctggaacaga gcgcttagac aaaatcgagc gaccgattcc
    34921 ttccttcagc aacgcaacaa ttacatcgtt acttttcacg atcatcttct tatcttggat
    34981 attcatctct tcaaaataac gctgcgtgta atgaaaaaca ccagagtttg cttctcttac
    35041 aagccacaat ttgctttttg ggtccccagc gatgactagc tggtcttcca tcaaagagta
    35101 tctttgtacg ccggaagtct ctaatggctt ttcgataaaa ccaaaatcgg attcatgttt
    35161 cgctacttgt tctaatgatt catgagaatt cgtgatttcg atctcaaaat gcactttagg
    35221 aaaccttttg atcagatgtt tcatcaactg aggcaaaaga tagacagcaa aggtgtggga
    35281 agcaacgatc cgacatactt cttcttcatt ttgttcattg agcaattttt gctgagtttc
    35341 ttcccattct tctaacaaaa ccagtgtccg ttcatataat aagtcggctt gcttagttgg
    35401 aagcatctct tttcttccgt tacgttgaaa aagatcgata ttcaattccc gctccaactg
    35461 tttgatttga ttcgagactg ctggttgaga taaaaacagt acttctgctg ctctggaaaa
    35521 atttcttgtt tcatatactg ctcgaaaagt cgttaataac ttaaacatgg caccacttcc
    35581 ataacttttt atgataatta ctataaaaac tatttgattt aaatatacaa aaaaccatct
    35641 ataatagaaa tgtacaacaa aacagttgct gatccaacta gtaacttaga tgaagacaat
    35701 cagctgtctg cttgctcgta atcatacatt cctattcatt ttacaatgta ttcgttcatc
    35761 ttggtactaa aatctattaa ataaaaagga gaatattata tatgaagaac tttttgaaaa
    35821 ttattccgat cccgatctgc gggttgatcc ttgggttagc ttcccttgga aatctgttta
    35881 aagactatca ccatgttgct ttaggcaatc taactggcgg tatctctatg attcttatga
    35941 tattcatttt tgttaaattg tttatcttat tcgaacacac gaaacaaacg ttgcatgatc
    36001 caatcatcgc ctccgtttca ccaactttta cgatgtcact catggttatt tgtacttatt
    36061 ttgtttcata tgaaagtatt gcaccaattg tcaaattcat ttggctgtgc gctgttatct
    36121 tccaagtgat ccttgtcttt tatttcaatt atcaccatgt tatcaaagct gatctttcaa
    36181 ttgaagcaat ttatccaagc tggtttatca tttacgttgg atttggggtc atcactgtaa
    36241 ctgccgggaa cttcttccca cttattggaa aaattttctt ttggatttca ttgatctgct
    36301 atgcgttctt attgccgatc atcatcaaac gtgtcttttt cgtaagaaat atggctcatc
    36361 cgacacgtcc gctgattacg atcgttgcag cacctggttc tctttgccta acaggttatc
    36421 ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc attgttcgct ttatctcaag
    36481 tattgtattt cgttgtgctg tctatgcttc cacgtttgtt caagcttcgt ttttatccaa
    36541 gctatgcagc ctttacattc ccgcttgtta tctctgcaac agctatattt actactgttc
    36601 attacttcaa cagtttaggt atctatagta gcgtattgga tttcttaaaa gttgcggaat
    36661 gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca ttacgtacgt ttcttaatta
    36721 aagaacatag caaacatgga aaatttgttt ctaaaaaaat cgcttaataa tcgattcaat
    36781 aggttgtgaa aaagctgttc tgcatcaagt aataagaacg gccaaacaaa aacagctgtt
    36841 catgtttttg tactggttgg gcttattacc gcagatgcaa gcttttgaac accgtttacc
    36901 aagaggtcgt aaaagaagtg gtcagcttca agaaataaga aggaatttac gaaaattgct
    36961 tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag ctacttctgg aacaccgttt
    37021 attcgaaaca agaggtcgta caagactttt gtcacgacct cttgttcttt tgtcaaaata
    37081 ctggtttagt gctactatgt tcgagtatgc ttttagtatt tattgacgaa aggaaccgat
    37141 caaatgaaat cattgtcaca tccaataaaa tctgtaaagg attcagcggt ccgcgaaatc
    37201 ttacccggtt tactgctttc ttttgccatc gctgccttca gcaggcttct tgctatttat
    37261 ctgccacagt taggtggagc gactattgct attttattgg gtattttatt aggaaatact
    37321 ttttttaaac agcctgttct agcaatcggc acaaaatttg ctgaaagcaa actattagaa
    37381 ttctctgttt ttttactagg tgcaactgtc acagctcaaa cgattgctca aattggtgta
    37441 aaaggaattg tttttgtgtt actgcaaatg tcagtcacta tcatcggtgc ttacttgatt
    37501 ggtaaaaaac tgcaattcag cgatacttct tctttgatga tggctggagg aaacgctgtt
    37561 tgtggttctt ctgctattgc ttcaatcgcc ccttccatcc atgcgaaaga ggaagaaaaa
    37621 ggacagatca tcacactagt caatctactg ggtactgtga tgatgttgac tctccctttt
    37681 cttggattac agttgtttgg tggaaatctc attgaaaaaa gtgcactttt gggtggtaca
    37741 ctccaatctg ttggtcaagt agtcgctggg gcaagcttac ttgacaattc tgttgtcgaa
    37801 ttcgccatgc tatttaagat tctacgtatt atgatgctcg ttgttgttgt ctatctgttt
    37861 gaaaaattca tgcacaagaa acaaccagct ctgtttgaaa cgccaactga tacgcagaaa
    37921 aaacgaaaat taccgcttcc ttggtatgta ttagggtttg tgatcttttg tttggtcaac
    37981 agcttgtttt ctttacctgt agttattgac caatcggcac attttatcag cagctggttt
    38041 gagatcactg ctttagcggc aattggtctg cgtttagact ttgcaaaatt catgaaagaa
    38101 ggtacacgct tcttatctta tggattagct gtcgggcttc tccaaacagt gatggcttta
    38161 ctatttattt ggctgatcaa agtttagaat gaacatgaaa aaacagttgt gattctcgca
    38221 tggaacaatg tccgaatcac aactgttttt aattttgcag atatccttct aacaacaaca
    38281 attggcgttt gatttcaacc ccatctattg cgtttcccat atatcctgtc agttttccat
    38341 tttgcccgat cactcgatga caaggaataa cgattggcaa tggattggtt cgatttgcct
    38401 gcccaatcgc tcgcacagct ttcggactat caacagcaac ggctacttct ttatacgttc
    38461 ggatttctcc ataaggaatg gtcgacaaag ctttccagac attttgctga aaaggcgtac
    38521 ctctctttat agataaagga acatcaaatt cttttctttt tcccgcaaaa tattcttcaa
    38581 actgttcttg tgtgcgcgtt aaaattcgct gattcgctga ttcgctttct gaaattggct
    38641 gaaaagatac agcagtcaat ccggattcat ctgcatctaa ccataaaaag ccgataggtg
    38701 tgtgtatttt cattttgttt gctcctagtc aatagactgg aacttcctcc tttttctcta
    38761 tccaaaacta cttgccaact aataaaaatt gttcttaaaa gtttgataaa ccgaggaaac
    38821 atggtaaact aaatacgtta gtttacaaaa agaatacctg ttcttttacg taaaatcaaa
    38881 ttttaaaggt gttatttaag gtttattaaa ttttgaatgt aaaccatata taaacatacg
    38941 attgaaagga tagaaacgat gaaagtatca attgttgtcc catgttttaa tgaagaaaaa
    39001 actgttcctc ttttttttga tgaggttgaa aaattcaaag gtgcccatga gttcgaatat
    39061 ttgtttattg acgacggatc aaaagacggt acgttagcag caatcaagaa gctagcctca
    39121 gcttatcctt atgtccgctt tgtctcattt tccagaaatt ttgggaaaga agcggctctg
    39181 tacgctggat tgcaagcttc tacaggagat ttagtgaccg tgatggatgt tgatctgcaa
    39241 gatccgcccg aactgcttcc tgagatgatc aaccggatca ctacttctga tatcgattgt
    39301 gtcggcaccc ggcgttcgac tcgtgaaggc gagcctgcga tacgcagttt ctttgcgaaa
    39361 aaattctacc agttgatcaa taaaatcagc gatacagaaa tggtcgatgg cgctcgtgat
    39421 ttccgcttga tgactcgtca aatggtggat gccgtcctag aattaacaga atacaaccga
    39481 ttttcaaaag gattatttag ctgggtcgga tttaaaacag aatatatttc ttatgaaaac
    39541 cgcgaacgtg tggctggcga aacatcttgg tccttctgga aattattcaa ctactcgatt
    39601 gatggtatcg tgaacttctc ggatgcaccg ttaacgattg cttcatttat cggcgctttg
    39661 tcttgtgtcg gttctggtat tgcaattttg ttcattattt tgcgggcatt gttgtttggt
    39721 gatcctacat caggatggcc ttccatggtc tcgatcttcc tgttcattgg tggaatccaa
    39781 ttgttatgtc ttggaatcat cgggaaatat attgggaaaa tcttcttaga aacgaaacag
    39841 cgtcctgttt atatcataag agaaacagaa aaagtgaagc caaatgaatt gaagcctcac
    39901 caataatata cgtcaaatga agtaaacatt tttttaaatg aaaaaggact gtgacaaaag
    39961 tcttgtcaca gtcctttttt ccgaataaat ggtgttccag aagtagcttc ttcggaaata
    40021 agccgaaatt tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
    40081 gctgaccact tctatcacaa cctctttcat atcttattac ttcttcattg ctgcttttag
    40141 tgctgctgct aatgggcttt cttctggttc ttctgcttgt gcatattttt tcagcaagcg
    40201 tcgttcttca tgtttggtca ttttcttctt ctgctctttt ttatcaagca atttttctgt
    40261 cgttccatcg tatttacaac ggaaataagc accgttttta ccttcgatga tttccatttt
    40321 ccggtgacat tgcgggcatc gatgattaga gacttttgga tcttttcttc tgcggtagtt
    40381 gcaatctgaa ttggtgcaga catagatttt gccgtcacgt gtgtttttct cgcgcagatt
    40441 ggccccacat tctgggcatt tcttttgggt aatcgagaaa tcttgatatt cttgtttgct
    40501 tgatttgatc tcattcacca agcgttttgt ttctttttcg attccattca agaaggttcc
    40561 tgcttgtttc tttcctgcag caatagcttc aaggtctttt tcccagcttt ctgtcaaatc
    40621 tggtgttact aaagagggat ttaccaatac taataattgc ttacctttag gagatacttg
    40681 cagtccttga ggggtacgtt ccatcagttc agatttgatt agtttctcga taatctctgc
    40741 acgcgtagct ggggttccca gactgtattt ttccatttga ccaagcaagc ttgcttctga
    40801 caatggttta ggcggtgcag atagttcttt tttgatggcg aaatcgggat tgattctcat
    40861 tcctttttcc catttgactg tttccgtctc agtttcagtt tcgcctttcc atcctgcttg
    40921 gacgacacga ttttgccgaa aaatgaatcg ttctttacca aattcaaccg taacttttgt
    40981 ttggctgact ttatggggtt gagcaaacag tcctaaaaaa cgagagacaa tcatttgata
    41041 gatttttcgc tcttcattac ttaatttttc ataacgtgct ctgttttcag ttggcaaaag
    41101 tgcatggtga tcggtcactt tactgtcttg gaatactttt gtctgttgga cgatggctcc
    41161 gtttttcaaa tactgcttga cctcaggagc aaagtcgctg actgcttgca atcgttcttt
    41221 catcgtactt ttcatgtcat ttgtcagata tttgctgtct gtacgcggat aagtaacgat
    41281 cttatgggtc tcatacaaac tttgtacaag acttaatgtt ttctttgcag aatagccata
    41341 gcgttgattg gcttctcttt ggatctctgt taaatcataa ggcaatggcg cagattccgt
    41401 ttttaatttt tcttggactt ctgtgacagt tcctttgctt gtactgatca attgaacaag
    41461 tttttgtgct tcttcttgtg tttttaaagc aaattgattt ttttgaagca ttttggcttg
    41521 ttcttttcca gcttgcaacg tgatcgtgaa atacgtttgt ggacggaact gctcgatttt
    41581 cttttcttgg tctctcacta atgctagtgt cggtgtctgc acacggcctg ctgataaatt
    41641 atccgcgtac ttcacagtta aggctctggt cacattcaat cctaccagcc agtccgcttt
    41701 tgcccgggca agagcagatt catacaatgc atcatattct ttcgcaggtc ttagttgctt
    41761 gaatccagtt ttgattgctt tatctgtttg agaagagatc cataaccgct tcactggttt
    41821 attgaaatgc acatactcta agatccagcg agcaacaagt tccccttctc ttccggcatc
    41881 tgtcgcaatg actgcttctg agacatcttt tcgctgagcc agctgcttga ttgcttttaa
    41941 ttgatgtcct gttttaggaa gtggtttgat tcctagtttt ttagggatca ttggcaacgt
    42001 gtccatttgc cagctctgcc attccttatt cagatcttcc ggcattttca atcctaataa
    42061 atgaccaagg gcccaagtaa cgatcacctt gggtccttca taataatttt tgtgcttttg
    42121 attagcacca agcaccttgc ttaggtcttt cgcaacgctt ggtttttccg ctagaattag
    42181 ttgtttcata aaattccttt ctgctttcta ctgtgatggg ctgatgattt ttcaacaacg
    42241 caagtccctt gtattgctgt aaatcatcgt cacactcttc acaccagcgc tcatctccgt
    42301 cattccaaaa ggcgctgaga aagttacttt ttgcattgat atattcataa ttttgatgga
    42361 tttcgttcca ttgtttttcg tacgcttgtc gtgcttcttc gaaagactcg aatgtttctt
    42421 cttcttcaat atcttcttcc cagtcttcaa aaaaccacca aggctcattg tccccgaaca
    42481 tggtaattac ttgatacata ctcgtgctcc ttctttcagc ttttctagac tcatcttagt
    42541 cacttttcaa gaaagttgca agaattttct cttataaaag ggtcatttaa tgaacatctt
    42601 aaaattgtta caaatgaatc tgattgttta aggcaaagta gcgataaagt tattgatcat
    42661 ccaaaaatag ctgtcttctg gatcgattgt tggttctttt gtaaagtatc ctaaaaaacg
    42721 taaggaaaga taaccgtgga tcatactacg aagttccctg cttcgatgaa ctttttcttc
    42781 tttcgttaat tgaaaagcct caaatatctg caaaatgatc tgattcgttt catggattcc
    42841 atctaataaa acagcttcat tggtatgcgg tacactgatc agtaactcat acactgcttg
    42901 atttgaaaaa gcaaaggatc gataagtttc tgcatagatc tgcagtgctt cctgaccact
    42961 ttttcccaca agagcccgtc gcagctggtc attaagttcc tgcagaagtt tcgctgttag
    43021 cgctgttttg acatcacgaa tatttttgaa atggttatac agcgagggag ccttgatatc
    43081 caagcgtttg gctaaatgct gaaaggttat ttgctgaaca tccatctctt ctgctagttc
    43141 tcgaaagcag tcgatgattt tctcttgaga cagatttctt tttttcattt ccatgtttcc
    43201 tctcataaaa taaatccttc actctttcag tttaccacga aaaagaaaga gaaaaaagag
    43261 actttcattg ataaactaca tattgtagtt tataataaag agctgtagat gaaaattttc
    43321 agaaagaagg agtctaattg gctgcaagaa taaaggaaaa attatttagg aaaagagaaa
    43381 cttgggaaca aaacttgttt gtcttatggt ttggaacatt tatggctggt atcggattta
    43441 gtttagtcat gccttttatg tcactttaca tagatacgtt aggtaattat agtacgtcac
    43501 aattgaactt ttggagcgga ttgacttttt catctacttt cttggtgact acgcttatct
    43561 ctccttggtg gggaaaatta gccgaccaaa aaggaagaaa attgatgctg ttgcgtgctt
    43621 cattaggaat ggcaatcgtc atttctttga tgggttgcgt gactagtgtg tatcaattag
    43681 tcgcattgcg tctgcttcaa gggatttttt ctggttatat cagtaatgcc actgcccttg
    43741 tcgcaactgg gacgccaaaa gaaaaaagtg gtcaagttct tggaacctta gcaactggtt
    43801 ctgttacagg aacattactt ggaccgcttc ttggcgggat ctctgcttca gcgtttggct
    43861 atcgccctac ctttttcatt acagggatca tcttattttt cgtcttcttg ttgagtctgt
    43921 ttttcgtcca tgaaaaattt gtcccagtga aaaaagaaaa catggtttct gccaaacaga
    43981 ttttcaaaga cttgaaatat ccacacgtcg tcatcggtat gttcgtcaca acgatgatca
    44041 tccaagcatc caacaattcc attagtccaa tcatcagtct gtacattcgc caattgctgc
    44101 atggacatgg gaatgttacg ttgatcagcg gaatcattgc ttcgatacct gggattgcca
    44161 ctttgatagc cgctccaaga tttggtcgct taggtgacaa gattgggagt gaaagaatac
    44221 ttgcgattgg tttgggtttt gcgattctgg tttatatccc aatggcattc gtcacgaatg
    44281 tttggcaatt agctgcctta cgttttttga ttggtatctc tgatgcttgt ctgctccctg
    44341 ctgtccaagc attgatcaca aaatattcgc ctcatcaagc tgctggacgg atcttcagtt
    44401 ataaccaatc tttccaagca actggtaacg tagtagggcc tatgatcggc tccagtgttt
    44461 ccagtgcatt tggttatcgc ggcgtctttc tttcgacttc tcttcttgtt ttggtcaact
    44521 tcttgcttgt acgacacaat acacaagaga tccatcagca agaaactgca gaagaaaaag
    44581 cttcaggagt ctccatagct tcagggcact ctccttctca tagacaataa gcgtaaatga
    44641 aaaacactgc ttgaacagtt gtcacagact gtccttgcag tgtttttgtt taggcctgtt
    44701 ttttcaagaa ctcagataag aggaataatc ccttttccaa ggtttctttt ttacaacagt
    44761 aacctagtcg ggcatgcttc ggtaaatcaa aggcacttcc tggtactaat agtactcctg
    44821 tttcttctaa taaattgata caaaatgtct ggtcatcttc ttcgatggct aatttaatga
    44881 aagaagtaga gacgtaattg ggagcgacaa gttcaacttt cggttcattg gctacccatt
    44941 gttttaaaat cacaaggttc tctgtaatga tctttttgtt tcgcgccaat attttttctt
    45001 tattcttcaa tgcatgtaca gcaagatcat ctgacaggac tccgccgcaa atcatcgtgt
    45061 agtctcgata ctttcgaaaa acttctgcca actcaggtcc agtagctgtc cagccaatac
    45121 gaatacctgg aatggagtag gttttggata gggaattggt tgctatacct ttttcataga
    45181 catctacgat cgacaagaat tcacctttat ccgttaaagg cgcatatact tcatctatca
    45241 atacatatgc atctactgta cgagcaattt ctgcgatttt ttctaaagtt ttccgatcta
    45301 gcaatgtgcc tgtaggattg tttgcactat tcaaacagat gatttttgtt tcaggtttga
    45361 ctaaggcttc tagctgttct aaatcaaact gccaatcttc ttcttccttc aaatgaacaa
    45421 agtcaacagc ggcacctaaa gatttgggga tgtcatataa ttgctgataa gtaggaagca
    45481 tcgaaacaac atggtctcct gcttccacta acgcgtatag agctaaaaga ttagcaccag
    45541 tcgctccatt cgtttgtaag atgttttccg gatcgacggt ttgataaaga gaagcgactt
    45601 cttgtttgaa aacatctgat ccttcgatcc agccatagtc caatggttcg tttttgcgtt
    45661 tttcgaaaaa tttacttacg ctagtcccat ctaagccaac gagttcgtct aatgtcaatg
    45721 cttcgatcga gctttgtgca atatcatata ccgctttctt ttcccattta tttagccatt
    45781 cttctacacc gaaatttgcg attttcatgt ttctttcccc cttatatctt gatccagcct
    45841 acagcaagca acccgattga aagcagtgcg gccacacaaa tcagcccaat cattactttt
    45901 tcttttcccg taatttgatg tttggtttca cgacaagcga tccagtagaa gcaaaaacca
    45961 ggaagatagg caatactaca taaaaggaca taagaaaatc ctgctaaaat gatgcccatc
    46021 aattcaaaaa ctacagcaat cccaccgatc actacttgtt ttttgattcc ttcttttaaa
    46081 gaaaactgga cttgatagat cccgacaagt agataacaaa tcaaaattgc cgctgtacat
    46141 aaagaatagg caaattgata ggcataatca gtaactaaga aagtcaataa gaatagatta
    46201 gtcaagattg cagtaacaac taacgaataa gttggggcat tttttttatt cgtttttccc
    46261 caacctttcg gcaacagacc gtctcgagcc atcaacatcg ttgtttctgc tgggagcatc
    46321 gtccaagaca accaagaacc aatgatcgaa ataatcaagc cgatattgat cagcgctgct
    46381 ccccaatttc ccacgattcc ttttaaaata tttgccatag caggttgtga aatagttgct
    46441 aactcttctt gagataagac gccgtatggc aagatcgaag caaggatata gataaacaat
    46501 aaacaaagca gaccaatgat cgatgcttgc tgggcttctg aacgtttctt cgcgcggttg
    46561 gctaaaacac ttgcgccttc gatccctaca aagacccaca tcataaccat caaacaacct
    46621 ttaatctgca accagatcgt tccttgctgc cctgttccat tcactagatt atcagatacg
    46681 ttaccccaaa aatcagcagt gaatatattc actttaaatg cgataaatac aaatattaaa
    46741 aataggaata atggcactaa tttacagatc gtcacgattg tattgatgac gctcgctcct
    46801 tcaactccat tgtttactaa taaagtcaga ccccaaataa aaatacttgc aaataaaata
    46861 gaaggaacat tttgtccacc tttgaatatc gggaaaaatt ctcccatggc gctcatcagc
    46921 atcgttgcaa aagcaacatt tcccagccac gcagacaacc agtaacccca accactgatg
    46981 aagccaccta atttaccaaa tgaagcttcc gcgtaaccga aaataccacc atctagatct
    47041 ggacgctttt ctcctaaatg attcagcgat aataccaaag ctaaaatacc aatcccaacg
    47101 attatccatg aaaggatcgc tggccctgga gctgcagaac tagccagatc acttgtgatc
    47161 ccaaacacac cgcttccgat tgacgaactg acaaccagag caaccagtcc ccatttgcta
    47221 atacccgtcg atttcttttc catttccatc accctcactt ataaaattga acaaatcact
    47281 tgcaaaagat tcccttctat tttgcaactg ctcttgctta acaaaaagca actttattca
    47341 tattattgga tattatgaac tttttacaca agtatttcaa gtataaaatg aataaaaatt
    47401 aattttattg caaaaaaaca gctatgctat ccaaaagaaa aggtgtttct tttgttagcc
    47461 atagctgttt tgattcattt aatatcgctt aaacgtattg taaaactttt gtttcttgat
    47521 atgcgtggtc gatcaaacca ccacccagac attccattcc atcataaaat acaactgctt
    47581 gtccaggagt gattgcacgt acaggttcgt cgaatacgac ttctgcacga ttatcatcca
    47641 ataagcgaac tgtcacagga acgtcttgct gacgataacg gaatttcgct gtacacttga
    47701 attcttttgg cattggttca ttcgtcgtaa agtggatttc acttgcatcc aagcttgtgg
    47761 catacaatgc aggatgatgg aacccttgcc ccacatataa tgtgtttgtc gctagatctt
    47821 ttcctacaac aaaccagggt tcttgcgaat ctcctccgcc accgatccct agtccttgac
    47881 gttgaccaat cgtataatac atcaagccag catgttgtcc tttgacttca ccatcaagag
    47941 tgaccatatt tccttttttt gctggcagat agttgctcaa aaattgtttg aagttctttt
    48001 caccaataaa gcagattccc gttgaatctt ttttcttagc agtcgcaagg cctgcgcgtt
    48061 cagcaattgc ccgtacttct gatttttcca tgccgcctag agggaacatc gtttttgaaa
    48121 gctgttcttg tgataattgg ctaaggaagt aagtttgatc tttattattg tctactccac
    48181 gaagcatgtg gaccacgccg ttttcatcgc gagtgacttg cgcataatgt ccagtagcta
    48241 cataatcggc gccaagatcc attgcataat ccaagaatgc tttgaatttg atttctttgt
    48301 tgcacatcac gtctgggtta ggtgtacgtc ctgcgcggta ttcggctagg aaatattcaa
    48361 atacacgatc ccaatattct ttttcaaaat tcacagagta ataaggaatc ccgatttgag
    48421 cagctacttt cgctacatcc ttataatctt ccgtggccgt gcatacaccg ttttcgtccg
    48481 tgtcatccca atttttcatg aatattccga tcacgtcgta tccttgttcc tttaacaaaa
    48541 gtgctgttac agatgagtcg acaccgccgc tcatccctac gacaacgcgt gttttgctgt
    48601 tgtctgtcat gatatcacca tcatttcaat tagattctga aacatctacg agttgaaggt
    48661 cgcaactttt cagtatttta cattatacgt catatttctg aaaatttcat cccttaatta
    48721 tcaagtcgta aaaatactgt tctactggac ctattcagta cacaaacatg atagtcaacc
    48781 aaaaaatcac tcatcttttg agcattcgat ataaaaaatt ggcatactca taaaaagggc
    48841 cagcctttcg gcaataagga ataattttat aaattgtgaa aaactatttt tcaaaattgc
    48901 ttcttatcgc ttaaagctgc acgtctcatt tacaaccttt tctttttaga tgttatgagt
    48961 tgctcagata agtgattttg tttactctaa gaaaaaaggg aggcaaaaga tacatgaatt
    49021 actttatcag tgatatgcac tttttccatg aacgcttatt aggaaaaaac gactttgctc
    49081 cgcggctctt tgcaaatgtg gatgaaatga accaacagtt gatcactagc tggaatgcag
    49141 taataaaaga aaccgaccat gtttatcatc taggcgacct tgctatgcat ccgcaatatg
    49201 aaaaagcaaa tgcagaaatt ttggaactgg tcactcaact gcaaggaaca atccacttga
    49261 tcaaagggaa ccatgacagt cgcgcttttt tccgttattt agaaaaaaat gatcctaggc
    49321 ttactgacgg aagtcccaaa ttttattttt atgatgtagg tgccatcgtt aaattcgacc
    49381 atcaacaata ttacttgact cattatccga tgttgctcgg gcctaacgac actatccgca
    49441 atcttcatgg acatatccat cattacagcg tacctatcga gaacgatgtc aatgtaggcg
    49501 tagacgcacc ggaaagagaa ctcttaaagg aaaaactacc atttggcact ccgttatctg
    49561 agcaacaaat caaagaaatc tatgaagcaa agaggaagta cgataggtcg tgaaaaaact
    49621 gccctatatc aagtattaaa caaataaaga taattactca tatttttcat ttgagtaggc
    49681 ttattgccac aggaacatta ggatcagaaa tggagttgta acaagacttc tgtcacaact
    49741 ccattccata ctattcgtct ttttgctcat ggtgttcttt taccagtttt ttctgtaatt
    49801 ctttatcata atttcgggca gctgacgtta aaaataaaac gattccgcat aataaaatcc
    49861 cgattccgga aaacaagaac attttttcta cccctaaacg atcagctaat ggtcctgcaa
    49921 ataataatcc aattggacct gccaggttca tcaaagagtt gaagttccct aagacacgac
    49981 ctaaaacatt cgattcataa ctctgctgga tcattgccat cagcagtgta ttgaaatatg
    50041 gcgttgcaca acctgctcct gcattcaaga taagaaagta caagaaccct tgactatcgt
    50101 ttggaaccaa tccgcttgca ccgatcgtca ggcccataat gatgtaggct ataataatag
    50161 gtttcattcg gtctttccat gttcctataa aactgatcag tgcaccgcct aagagcattc
    50221 cgactgcgta gactacttcc actgctcccg cctgtccaac ggaaccacca aagtaatcta
    50281 gcgtcatcaa tggatacaga ctgattgctg gcatgaacaa cagcatcaca aatgcaccat
    50341 tgatcgttat gtaccataac cctttattat ccatcaattg ctgcagccca aattttgcat
    50401 ctttaaaaat agtaagcgga acttccaata tttcaggaga aacttttggg atcttcacaa
    50461 aaatcaataa gccgacacca aaaactgccc ccaatacatc taataaaata aggtaattga
    50521 caggaacgac tgaaaacaaa gccgcaccta gagctggcgc aatgatgaaa ttcgctgatt
    50581 ggaccattcc taactgtcca ttcgtccttg ttatgtgaga agatggaacg attgtcggca
    50641 taatcgactg gatcgttggc atttggaatg tttgtgcgac cgaacgcata aacaaagaca
    50701 caaaaactag ccaaatcggg aaggattctg aaatcgttcc gactactgct aaaataagcg
    50761 cgaaaatcgc tacaataata tccgtgacaa tcaaaagagc ttttttatcc cagcgatcca
    50821 ctagcggtcc tacaaatggg cttagtaaaa ccatgggaat cattcctagt aaagtagcaa
    50881 aactcaaaat tgtcgccgaa ccggtttctc ttgtcaaata ccagatgatc gcatattgga
    50941 cgaccatact agtgattcct gacaaaaact gtcccgataa aaagaacaaa taatttctct
    51001 tccaattcgt taaaacgacc gactgttcat tttccataaa catccctctt ttctttttca
    51061 ttttgtatag cgtttgcaca acaatcatta tacgggattc ttttttcaaa aaataccttt
    51121 ttccctaaat aacaatcgtt tcaatttaaa tttctttact tagaaacaat aaatcagcaa
    51181 aatattaaaa ataacaacat gtgttaaatt taaaaataaa aaagacaact aatttgcgtc
    51241 gtccttacaa agttagtcat ctaacaatag gccgtttcaa aactagttgt ctttttatat
    51301 ccacagatca ttcgactttt tcgaataacc cacggctaat catcccatcc atcagaaaat
    51361 aaaatttatc ttggctcatt ttctgttttg gatctttgaa aatattgact gctttcaatc
    51421 catttgctgt agtgatcgac attttcaatg tttgaatatc ttttgataca gtgattttta
    51481 atttgaatcc ttctttgctt tgcggcgtgg catctaatgg tcggatcaat tgataattgc
    51541 ctccgtttgt ttctgtaaat ccattatcgc gcaatgtata tctttttgca tcaggatgca
    51601 aacgatagct aattggtgcg cccagtaccg ttgctgttgt ttcaaatgcc atgattttca
    51661 cctcgataaa attagtttct ctttattata aaagtttatc ctgattttta ctaggttttt
    51721 cagttaagtt ccctaaaaaa tgaaggcgtt ctctcagaca tctgttcata taagaatgac
    51781 ttcactagtt attttttgac agcacgaact aattgatcaa ggaaatactg gatgtcgtct
    51841 tcggtatttc ccaaaccaaa gctgatacgg atggattctt ttagtatcgg tgtatcttct
    51901 ccatacattg cttctaatac gtgtgaaggc tcgatatttc ctgctgtaca agctgaacca
    51961 gtagaaatag cgaccccatt aagatcaagc ttcatcagta gcaaatcatt tgcttcgcca
    52021 attaagcgaa gattcaacac atgagggagt ttattcgtta aatcaccatt tacttgataa
    52081 gggatttcgt ttgcttctaa tgtatcaaga atcaattgct ggaatccttt atatttgttg
    52141 ttacgtgctt cacgttcttc aggtgacagc agttcaactg cttttgccat accccagatc
    52201 cctgctaaat tttctgtacc tgcacgccgc ttttcttcct gctccccgcc taaaagcaat
    52261 gcagggatat ttactccgtc tcgtttatat aagaaaccga cgccttttgg cccattgatt
    52321 ttatgagcag agatacttaa taaatcgatt cctaattctt ctggatggat cgtttggttt
    52381 ccgtacgctt gtaccgcatc tgtatggaaa taagctggat gatccgctaa aagttcaccg
    52441 atttctttga ttggcatcaa atttccgatt tcattgttcc cgtacatcac agagaccaag
    52501 atcgtatctt ctcgtaacgc ttttttgacc tcttcgatcg acagattccc tttttcatct
    52561 acaggcagat atgtaacgtc aaaccccttt gtctctaaat atttcatggt attaagaaca
    52621 gcaggatgtt cgatagctgt agtgattaga tgtctgcctt ctttttgacg cgagaacgct
    52681 gtttctaaga tagctgtatt atccccttct gttcccccac tgttaaagat gatctcgtga
    52741 ggttttgctt gcagactgtc tgcaatgatt tgtcttgctg tttccaattt ttcatgcgcg
    52801 tggcgaccaa atccatgtat gcttgaagga tttccaaacg tgtcttgcat gattgccgtc
    52861 atcgcttcaa ttacttgtgg atgcatgggg gtagttgccg catgatccag ataaatagtt
    52921 ttcacttcat tcatcccttc caaattattg ctaggcacat tctagcataa aatagcgaac
    52981 aaaccaaaga agagctcatt tttgtctaga ggacgtttca tgggcataga aaaaaggagc
    53041 tgtgacaaaa gtcttgtcgc agctccttga agctgctcac ttctgtcaca acttctttcc
    53101 ctcttttttt tgtttattcg aattcttttt cttccagacg gaataacgga ctcatcggtg
    53161 tattttcatg gatgcgtttg accgcttcac ccattaattc tgaacatgta acgattgtta
    53221 agttttctgg atgacgattt tcttctgtga aaacagaatc agtgatacaa atatctttga
    53281 ttggtgcatt gtctaaaata cttttcgcat gatcggacaa taatccatgt gacgcacagg
    53341 catatacttc ttttgcgccg ttttctttta atacatttgc tgctcgtgca agcgttgctc
    53401 ctgtgttcaa gatatcatct accatgatac atgtctttcc ttgaacatca ccgatcacat
    53461 aaccaccctc agttgaagca tcatctgcat gatctacgat ggctaatgtg ctgttcaaat
    53521 attctgaaag actacgtgca cgctgaacac cgctgttttt tggcgaaaca actacgatgt
    53581 catctcccgt cagacctaat tgacggtaat aatgagcaaa caacggcatc gtaaataaat
    53641 tatctacagg aatatcaaag aatccttgta cttgaaccgt gtgcagatct aaagtcagta
    53701 ctcgagttgc ccctgcttct tcgatcaagt tagcgatcaa tttcgcagtg atcggttcat
    53761 gaggtttcgc cgtgcggtct tgcctagcat acccatagta aggcaatacg acattgatcg
    53821 ttttcgcact tgctcgcttc attgcatcga tcatgatcag tagttccata tagtaatcat
    53881 tgacaggtgc attcgttgat tgaacgatat acacatgatc ccctcgaata ctttcttcga
    53941 tattgatgga aatctcgcca tcactaaatt gcttcacgac gcttttacct aattctgttc
    54001 cgaacacttt cgcgattttt tcagctaatg gacggttgcc attcaaacta aaaatcttca
    54061 acgtgtcatc ctgatactta ttactcatgt agtcctcccc aaaacttctc tattcttcga
    54121 tagtttaaca tatttttcca agattttctg ttaatttcag caaattctta aggaagtgaa
    54181 actgttccgt tactccaact ggcaggaatg actttatgat aatcgcccca gttgtcgtgt
    54241 actttgtaat aacgttctcc tgtttcagtt tcaaaataag cgtacgctgt cacccaatga
    54301 ttgccatatg tactgccaag tactttcaaa ataccaatca tcacaggttt gccttcacgt
    54361 atacgttttg tagctcgctg ccatgaacct agaagagttg ctcgtgcacg ctcatgattg
    54421 ccattcttct ttaaaaaact agaaatccct gtactaacct gaaaaggaat cgtaggaagt
    54481 cctagtggtt ggatctggct acgcaatgcc ttcgtcaaaa ccaacgaatc agccgtattt
    54541 ttcttgcgaa tctcatttgg aagcatccac cccttacgat agtcttgata ataggcaagg
    54601 agaactgctg ccgcgtaagt accacaaaga tagcctgagg gggtagccca tttcttatac
    54661 ctcaaaaaac gttcttctgg caatcccacc cagcaatttg cgagttcctt tcctgacctt
    54721 ttttcttcga tcaaaacggg aatatcttct tttctgttga tccatctaga taactcgatt
    54781 ggctcttcat tgatcagctt ccatttttta caagaaagac cctcttgata agtatatttt
    54841 gctggagaat attctaccgg atgtcctgat tgatcgataa tcacataact ttgatcttca
    54901 aaaaccagag ctaaaaaaag caatttactt tttcttgact gcagctgctg agtgctggct
    54961 aattttttaa tttttttatc tactttgaaa tataaaggtt tatccactac ttgattcagt
    55021 tgggatcgcc tccttttttt cattataagt gaaggattga aaaaaacaaa tcagtttgat
    55081 tgttcgaatt ttcaattttt tatgttctat ttgttaattc cttcattttg taagataatg
    55141 ggcacacgaa acaaaaaagg agcgatcgat gaatgaacaa agaacgattg aaacaagatt
    55201 tctatgaagc agtcaatgaa gaatggcaaa aaacagcaaa aatccctgca gataaaccag
    55261 ctacaggcgg tttccaagat ttagttgacg ggatcgacca acttttgatg ggagaaacag
    55321 acgatctgct tgcccatcca gaaaaagtgt cttcagaaaa aatgaaacat ttccttgcat
    55381 attatcaact ggcaaacgat tatgaccgaa gaaatgagtt gcatgctcaa ccgcttcaac
    55441 ctataatcga aaaagttgaa tcattgcagt ctttcgacga attgaataag caatttccag
    55501 aatggctgtt ggatacatta ccattgccat ttaatctgga tgtagatgca gatatgaaga
    55561 atgcgcaaac gaacgccttc tttgcttatc cgccttcttt attccttcca gataagacgt
    55621 attatgcatc agaccatccc aacggtgcac aactaatagg cgttttcttt gatatggctg
    55681 ttcagttatt agagcttgcc ggcaaagaaa aaagtcaggc agaagcaatc acggaacaag
    55741 cagtgcaatt tgataaattg attgctcctc atgtaaaaag tgcagaagaa aacgcagatt
    55801 acagcaaaat gtataatccg caatcttttg atacatttat taaatacaca gataaactgg
    55861 acttgaaaaa acttgtcacg ggtttgattg ggacaactcc agataaagtg atcgtaactg
    55921 atccagtgta cttcgatcat ttgaatgaca tcctgacaga agctcatttt ccgttattca
    55981 aaagctggat gatcattaaa acagtacgtt ctcttagtgg ttatctatca gaagaattcc
    56041 gccaagtcag cggaatctat tctcgcgtat tgtctggaac agacgaagca atgcctcaga
    56101 aaaaagcagc gtattacctt gcctctggac aattcgatca agtagttggc gattactacg
    56161 gaaaaaaata ttttggcgaa gctgctaaaa aagacgtaga acaaatggtg aaaaaaatga
    56221 tcgccgttta taaaaaacgt ctagaagaaa atgactggct tggggatgca acaaaagaaa
    56281 aagccgtcat aaaattaaat aacttaggta tccaagtagg ctaccccgat aagatcccag
    56341 cattattcga ccagttcaaa acagtacctg cagatcaggg tggtactttg ctttcaaata
    56401 ctcttgtttt cagcaaactc acattaaaag atcgtttcag caaatggaac aaaccagtgg
    56461 atcgttcaga atgggaaatg agtgctgaca cggtcaatgc ttattatcat ccatttcgga
    56521 atgtgatcgt ctttccggca gcgatccttc aagcaccatt ttacagtcta gaacaatcaa
    56581 gctctgctaa ttatggtgga atcggagctg ttatcgctca tgagatttcc catgcatttg
    56641 ataataacgg cgctttattt gacgaatatg gcaacttgaa caactggtgg acagaagaag
    56701 atcttacaca atttcaaaac aaagcacaag caatgatcga agaattcgat ggtctgcctt
    56761 ttgctgacgg aaaagtaaac ggaaaattaa ccgtttcgga aaatattgct gatgcaggcg
    56821 gtctaagctg tgcattggaa gcagcaaaaa cggaatcaga tctttctatc gaggaattct
    56881 ttgtcaattg ggcaacgatt tggcgtacaa aagcaaaaaa agaataccaa caacttttac
    56941 tgcaaatcga tgtccatgcc cctgctaaac tccgagcaaa cgtgcaacca aaaaaccttg
    57001 acgaattcta tgaaacattt ggtatcacgg aacaagacgc tatgtatcta gcgccagaaa
    57061 aaagagtgcg aatctggtaa gaggttgtgc cagaagtggt cagcttcaag aaataagaag
    57121 gaatttggga aaatcgcttc tcaaattttt gtgacatttc ggcttatttt tcgaagaagt
    57181 tacttctgga ataccatgta ttagaggttg tgaaaaagct gcttagtttc aagtagtaag
    57241 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttac taccgagaaa
    57301 ctggcttttg aacaccgttt atcgagaggt tgtgaaatca gcgtcctgac ctgagtatta
    57361 gagaaaaaaa cggaaaaata gttcctcata ttttgccgtt tgttgagcta ataccgaggg
    57421 tcagctgatt gaacaccgtt tagtggagag attgtgaaaa agctgtcctg catcaagtaa
    57481 taagaacagc caatcaaaag cagcaaggag aacctcatct ataaaaagat agaaggaagt
    57541 gagacatcta ttggtctcat ttccttctat ttttactttc ctcagtcaat tgttttacat
    57601 cataaaagga gaaattccac ttattttttt cgctgtttca tgacataaac aactacaccg
    57661 attaacaaaa ttcctccagc taatgctagc aacgggttat taaattctcc cgtttttggg
    57721 agtccttgag tgccattttt ttcactttct tttgctgtcc tatccggatg agaaggtttt
    57781 ccatttggtt ttccatttgg tgattcattt cctggatttt ctctttctgg tttgtcattt
    57841 cccgggggca catcggcagt ttctcgcaca gtgatcgctt tttgctgggt aacagattct
    57901 gtatgagcag accatttttc cccatcaaat atttccgaac gataagtgac ttctagcgta
    57961 tattctcctt ttgaaggtgc tgaaaaaata gcggtatgat tagaaaattg agcacttgac
    58021 tgtgtttcaa cgatttggat cttttctggg aaataacgca tatcttcaaa gacaggcgtt
    58081 ccttgatttg gtgtgaaagt tgacacaaaa actgtaaaag gcttcagttc aatgatattt
    58141 ccttctgcat tctccgccac accatttgct tcttgtataa taatcggatt attttgttca
    58201 tttggttttg tctgatttgg ttcttgtacg attgcatact ctggatattc cgaagacggt
    58261 gaggtttctc cgtcaaaaat agcacctaca gataatggaa gaccatccac tctttccttt
    58321 tctgtttgac gattccccgg tttaatctgc atcagtccat gaacatggat acttccattt
    58381 tcatagcgcg taacaggctg ctgaccttct ttcgaacatg tatttagaga ctcgatccaa
    58441 tcttttgata tggtatgtcc aagagtattt tctgattgtt tctctcgttc attccaatag
    58501 tagttcaacg agtggtagat ttgatcttcg ttttgattca atgggcggat ctgctctctc
    58561 atctcaagat tctctgttcg gaaagataag ataccagaag catggtagtc tgtgtttcct
    58621 gctgaagagg tataaagagc cacattatat gaaccgttat taaaacttgt actgctattg
    58681 acgataatat ctgttccgct attggaatcg attcctttcg caagattttc gaaagacaaa
    58741 ctattgatca attcatgagg gcccgttaaa gaagaaccgc ccattttgaa tccattaccg
    58801 ttaccttctc cctcaattcc tggtacccag ccgtttcgat aagcaactga gtttttgatg
    58861 attacttttc cgatcgaacc tgtttcattt ttagcaaaaa ggtcccaacc gtcatctgca
    58921 ttatgatacg cgatacaacc gtcaaataca tttccttctc ctattgtcag tttggccgca
    58981 aatccatcgg catcttcaaa tcctggatcg gcattttcaa aagatgtaca gttcttgact
    59041 aagttatgcg cgggccatgc ttcgaaagga tcatttgagc taccgctgat ttggattcct
    59101 gtatttccat tccgataagc atgaatctct tcgatcaaat tatgatttcc agaaatctgt
    59161 aatccttttt gcatagctgc actatttgta atgtcaaacc ctcgtaaacc ccagtagtga
    59221 ctgaacagtg tcatcccatt tccagttcct ttaaaatcaa gtacaggacg cttgttttct
    59281 ggatttttct ctgcaatcaa ctgaatcggg ttttctcttg tcccgttaac gccttttgga
    59341 atcgtcaatc ctctttcgaa ggaataagtt ccaggcgcca tgacgattgt ctgcccagca
    59401 tatgcgtatc tcaatgcttg tgtcagagat aatggatttt gtctgcttcc gtttcctgca
    59461 tctgaccctt ctggtgttac ataaactgtc gaatatttag gtttacggta gtccactgta
    59521 tgaagaatct cttttgtttc ataactagtc atctctacgt attcttctgg cggatagttt
    59581 ttatctggcg taaaactgaa agtaaattcg ttcgttcctt ccatcagttt tgtctgataa
    59641 tcaaattccc gattcgcagt gatagccaag ttttttgcgt tcttaagcac ctctcctgtt
    59701 gctttatttt taattgtcaa taatccgtca gcatttgctc taaaggacat agtatgatct
    59761 tggtttcctg aatgattact agaggtcaca gtgtaaatcg gatcaatcaa gcgagtaggt
    59821 ctttcttgcc caggaggatc tgtcgcagga tctgagtaag caacttcgat tccttctacc
    59881 ttgatcgtca tattccttgc tgcagcaaat cctgcataaa taaccgattc atctgaagcg
    59941 tataattttt cccagtcata catgatgtca gaagccattt cttctcctgt ttcaggatcg
    60001 taataatatg cctctaaacc agtattcgtt tttttcatct ctacgtccag tttagtaatc
    60061 gagttcgtgg ccggaaacag attcccatga ccgtttccga atatattata agaacctgtt
    60121 tctttttcca agaaccctgc tgaagtctct aaaggtgttg tttccactga gacactccca
    60181 ggagctggcg cagcttgcgg atcttcagat gatattcctg tgattgcccg tgtccccaat
    60241 ccaagtcgca tcgtatattt gctgccgctc gtgttgacca cttcttgtct atccgagtcc
    60301 cagacatatt cgatccgact gcctagtatg gcaaatgaat ttgaataaaa tgcctgccca
    60361 aacaaatgat tttttggtac tgcgtctctt accattaaag caaatccttc ttgggcattc
    60421 gtataggtcc aagattctat ttcgatcgtc gcccgcatcc taaagttgat gtctttgggg
    60481 attgcttgat aataataggt cattccatct gatccgcttg actggaattt tccgccgtta
    60541 ttcgtggaag agagccgcac gccgtcttct aatggttcaa tggcatacct actagcactt
    60601 gtgctttctc cgaaaacaac ccctttccac tcttcatttg cttcttcaga ttgctttttt
    60661 gtcttttcat tttctgattc tttcatcata ggatcatttc cttcttccgt atccatatct
    60721 tcactagttc ttggtatttc ctccattgtt gacatccctt caatgttcac gtgtgcattt
    60781 tcttcgttca cagactgttg ttcgttagca gcaacttcaa cgacagaaat taaaaccggg
    60841 gtactgagca taaggagatt catcattagc gcactgtatt ttatacgttt ttttaacaag
    60901 tgtattcctc ccgtaacaaa ttagaaagcg tttacttaaa gcattaccta atttattttt
    60961 actgtcaata aaaaacaaaa ttataataag tgtattttat aaaaagaaaa aatataactt
    61021 aagttgttga taataaagag atttattaac gtaaaaagaa taagtttttt taaaataacg
    61081 tataaaaaag agcataaaac aaagtcgttt gttttatgct cttcttttat tattttgtgc
    61141 tttttatttt atcaaatcac tttgtttttt tataaaattt ctgcgcctag tgtggactca
    61201 aaatgtctca atgcccattc atgtccaacg ggatcgaaac ttgccacgga atctttgaaa
    61261 atatggagtt tgtatcctag attatacgca tcgactgctg tatgcaacac acagatatct
    61321 gtacatacgc cggtcaaata aatatctgtg atctggcgtt ctcgcaaacg gatgtctaga
    61381 tctgttccac taaaagcgga ataatgccgt ttgtctatcc aataaacatt ttcctcttgc
    61441 tcatagtctt ggtataaact ttttaaagag ccgtacaatt cccgtccacc cgttcctatc
    61501 acattatgcg gaggaaataa gcggttctcc ggatgaaagg aatcttttgg atcatgcgca
    61561 tcaatggcaa aaacgacaaa atccttttga tcaataaact tctttgtatg agcagtcagc
    61621 tttttttcaa ttacttgtcc tgctgtccca gtagtcagct ttccatcctc tgcaacaaaa
    61681 tcatatgtgt agtcaatcga gatcaatgcg ttcatcttag tcctccttat acgagatgtt
    61741 tgacaaattc gatcaccatt tctgctgatc gtttgcctgc gtcttcgata aattcgtcaa
    61801 agctttgtgt cgccgagtga tctgctgtgt cgctcattgc acgtacgatc aaaaatggga
    61861 tattgaactg acgagctgtt tgtccaacag cggctccttc catttcgcaa gctaatgctt
    61921 cagggaaatt cgttaagatt tctttgattt tatctggcga gtcgacaaat gtatcacctg
    61981 taacgatcaa tccttctttt gcgttcaaat tcgttgcttt tgctgcttta accatttcac
    62041 tgcgcaaata tgtgcttgct tcataatata gaggcattcc tggtaattgt cctgggttgt
    62101 agccaaatcc tgttgcatct gcatcaaaat aagctacttt gtctgatata acgatgtcac
    62161 ctacttgtaa gccttcaccg attccgccag ctgaacctgt attgatcacc atgttcacgc
    62221 cgtattgttg gatcaacaga cttgtggtaa tagatgctaa gacttttcct ataccggaac
    62281 gtacgacgat cacttcgtgg ttacctaatg aacctgaaat aaataaagcg cctgcgcgtt
    62341 cccatgataa tggttcgctt aggttctctc tcaaaatttt tacttcttct tccattgcgc
    62401 cgataatacc gattttcatc tttttaattc cttctttcta tataaatgcg attgctaaaa
    62461 aaaccacaca taacattagg ataacaataa taagagattt catcaaaaaa gagttccatt
    62521 tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat tggtttattc tttttgcttt
    62581 ctttacgata aaagctggca atcttttttt cttcttgctg ataagctgtt tctgcttttc
    62641 gctgtttttt taatgactcg cttgcttgtg cttgttgtcg cttgcgaagt tcgcttcgcg
    62701 taataagcgg tcctttggcc ataagccgat ccctctactt tcctttggtc aatagttccc
    62761 agtattgaat cgcataaatc gtctttgcat cacaaatcaa ctgatctttc atcgcttgtt
    62821 gcgcctcttc aagagttaga tgatacaact ccagtacttc gtcttcatct tgtgctaaag
    62881 gattctcgac cttctctacc ccttgtgcat gataaatatg aaggacttca tttgcaaaac
    62941 ctggtgaaag atacatcgaa gtaagatggc tcagcgactt cgcacgatag ccagtttctt
    63001 cttctaattc tctagctgct gtcatttcgg gattttgtcc ttctcctgga tcgatttttc
    63061 cagctggaat ctccaaaatc actttttcta aaggttttcg aaattgtttg acaagaagca
    63121 gacgatcttg ttcgtcaaaa gcaatgatcc cgacaccgcc aggatgaaat accagttctc
    63181 tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac agcaacatca ataatttttc
    63241 cgctatagat ttctttgcga ctgattgttt tttcttcaaa ttgctcattg ttcagcatat
    63301 cttctcctgc tttctttgta atcataactg cttttttttc atttttcaat ttttctcaaa
    63361 aactccttat tagtttacca tagataaacc ttagattttc tctaaatata gaaaatcctt
    63421 ctttagtccg atactctttc tagtagtccg tatgctaaaa taagtatgta atcgaataac
    63481 gaaaagaatt caatactcaa cgataaatga catggagggt ttattatgat aaaacgaaat
    63541 tggccgtggc ttctagcatt ggtcttgcta tttctctttg tccgaaacaa tagtttttct
    63601 tttgttctag gacttttatt gataggtgta gttttagttt tgtggggact ctttggttcg
    63661 cgcaggaaaa agggaaaaca agaagaaatt cctgcactga ctgacgaact tgaaactcac
    63721 tatgaaaaaa gcggtatgac agcgaatgaa atttcatttt ttcgacaaac aatgaatcaa
    63781 acaaaaaatg agatcaatca attgcaaatg aatatgcagc agacagccaa acttaaagca
    63841 atcgatctcc gccatgatcc agtcaaagca gcgaaagctt tattcaaaga attggtgaaa
    63901 gaaccaaacc gactgcatga agcaagtcag tttctttata cgcatctgcc gaatctagtt
    63961 gatttgacaa ataagtataa tgagatcaat gaccatgaga tcaaaaacaa acagacctat
    64021 gaaaaactag aagaaagcgc gcagatcatc gaccagctgt cagctttaat cgcacaagat
    64081 tatcaaaaat tcgttgctga ggatctagat gatatcgacg tagagatatc tgttgcgaaa
    64141 cagagcttaa agcgtgataa taaatatgaa ccagaacaaa aggattaact cttttgttca
    64201 taaaagaaga ctcggaacat tcagatgatg tctggctgtt tcgagtactt tttctaaagt
    64261 agagacattc atgtaagaat cgagaacaga ttcaacaagg aggaattttt tatggatcat
    64321 aaaccgactg aaacaaaaga tgttacacca gttaacgata cacttgaaga tttattgaac
    64381 aacccgtttt caactccaac agatacgctg accacttcac aacaagcgga gattgatcag
    64441 ctccaagagc aacagacagc tgctcgttta attgacaaac taccggcgga acgccaagaa
    64501 caagctaaac agctagcagc aaaaatcgat gctaatgatg cacagtctgt catcagctac
    64561 ggatcggctg cccaagcaaa attaagtgaa ttctcacaat cgatgttgaa tcatgtgcaa
    64621 gcacaagata ttggtcctgt aggagattcc ttaactgaac tgatgtatcg tctccaagaa
    64681 gccaatcctg acgaactgcg tgccggagaa gggaacatct tccagcgtgt cttcgggaag
    64741 gtcaaacaat cgatctatga agtgacagca aaatatcaaa agattggtgc acaaattgac
    64801 aagatttcag tgaaattaga taaagaaaaa gacggtctgc taaaagataa tctgatgtta
    64861 gaacagcttt accagaaaaa caaagactac tttgatgcac tgaatattta tatcgctgct
    64921 ggagaattga aaatggaaga acttcaaaca acgatcattc cagaagcgat gaaaagagca
    64981 gaagaaactg gcgatcagat ggatgttcag attgccaatg attacacgca attcctagat
    65041 cgtctggata aacgtacgca tgatcttcgc ttagctagac agatcacgat ccagcaagca
    65101 ccacaaatcc gtttgatcca aaacacaaat caggccttgg ctgaaaagat ccaagcatct
    65161 atcgctacag ccattccgct gtggaaaaac caagtcgtga tcgcattgac cttgcttcgt
    65221 caaaaagatg cagtaactgc tcaacgccaa gtctctgaaa caacaaacga cttattgaag
    65281 aaaaattcag aaatgctgaa aatctcagcc atcgaaacag cgaaagaaaa tgaacgtgga
    65341 atcgtggata tcgagaccct tcaaaccact caaaatgatt tgatcgaaac aatccaagag
    65401 acattgcgta tccaaaaaga aggaaaagaa aaacgtcgtc atgcagaagt agagcttgga
    65461 cacatggaag aagatctgaa acaaaaactg ttggatttaa cccaatagat cacctttcgc
    65521 ttgttactaa aacaaacgcc caacaacagt ttattacaac tgttgatggg cgtttttctt
    65581 atctttcttc taacttctcc attggagtct atttctcatt catcttgctg tgtccatagc
    65641 catagccaaa ataaatgatc agtccaataa ccattacgat accgaacacg atccatgtca
    65701 cagtttgcag acgaagcatc aatacaatac aagtcaaaat ggagacgatt ggcaatagcg
    65761 gaacgaatgg cactttgaat tctccagctt ttggtttgcc aaacattttt ctcaacttca
    65821 gtaagcctag actaacaagc atcaaatagg cgagcgccat gatattcgtt agttccgcta
    65881 atacattcaa tgggaaaaat ccggcaaaga atacagctgc cacaccagcg gcataagtcg
    65941 cttttttcgg tgtacgatgc ttttgatcga tttctgtcat aaacttagga agtaagccat
    66001 ccttgctgac agcaaacagt aaacgagcaa gtgaatacat catcgagatc gttaccgtca
    66061 gtagcgttaa aattgcccct acagcgatca ccgcgcccac tgttccatgt cctacatacc
    66121 tcattgcaaa agccactggg tcattgactc ctagttcagt atacggaacg attcctgtca
    66181 agatcagcgt cacgatgatg taaaggacag tagcaatcag tatcgaacca atgattcctc
    66241 ttggcacatc tttttgcggg tttttgactt cctcggctgc cattgcaacg gcatcaaatc
    66301 ccaagaaagc aaaaaacaca agagctgcac catctagcac accggaaaaa ccaaaaggca
    66361 tgaatggctg ccagttatca ggtttaacga aaaatattcc tacaatgata aacaacgcga
    66421 tgataccaaa tttgacatat accatggcat tattcaaacg taatgctttc ttggcttcaa
    66481 gcgacacgat gtaagtgacg aatatcacta cgagcaccgc aatcaagtca atgtatgtac
    66541 cattttccgg attgtacccg ccagttaatg cttgtggaag ttcggcccct aaacttttca
    66601 aaaaaccttg catatagcca gaccatccgg aagcaacaga ggaaaccgct agtaaaaatt
    66661 ccccgatcaa caaccaccct gtcagccagg cagcaaattc accaaataca acatacagat
    66721 aggcatatgg cccaccaatc actggcactc gcgaagcaaa ttctgcgaaa cttagtccag
    66781 acaaaatgac aacgattgca gctaagacaa atgaaagtga cagtgctgga ccagcatttt
    66841 gattggccgc aacccctgtc accacaaata ttcccgtacc gatgatcgca ccaattccaa
    66901 gcatgatcaa atcagacgtt tttagttctt ttttcatctc actcgtatga ttgagattga
    66961 tctctttctt acgaaacaaa tccattgaag ttcctcccca ttttaggttg gaaaacagcg
    67021 attaaactgt tttcatatac cctaaaagga taccacctaa aatgactaaa aggcaaccaa
    67081 caataacata aatgagctct tttttcgttt ttctttcgcc aaggatgaaa atcccaccta
    67141 aagtagagat aatgatcccc atttgtgaaa gtgagaagcc aacagctaaa ccaagtgatt
    67201 tgactgttag aagcatgcag atgtttccta agccccataa taatccacag atcatgtttt
    67261 tccacacaaa ctgatcgact ttaactttac ggaaagcaaa gaagcttgcg cctaagatca
    67321 ttccgatact ttgaggtaag ataattgaca tcgcatccaa attcgcccag ttgacgatga
    67381 tggtatatac accataacca atcgtagaga agatcaatgc tctaaaaccc ttaccaaaat
    67441 caagcatttt attatctgta tctatttttc cttcgtcatc ttgtcgggca gtcaaatacg
    67501 caccgcttac aagaagagct aaagcaataa taccgtatac ataatctttc gtttgtgtcc
    67561 attcatggaa gaaaacggct cccgcaatcg tattcaaaat taattgaaaa ccagtagaca
    67621 atggtagccc tacagaaaca cccatgtact tcattccatg gaactgtcca ttttgtccaa
    67681 cactccaagc taagccggat aaaaatccga tcaagaaaat ccaaggggtg attacaggac
    67741 taacaacgaa aaagacaact aaagaaaaca gaaatgcacc gatcgtcatt cctagtgttt
    67801 gttgattggc atcgccacca attttaccac ttactaaacc aatactaccc catgccaaca
    67861 tagggactaa tgctattaaa atttccataa ccaatctcct tttatttcac atgataagaa
    67921 acttatcagc gaaaacgtta acaacacaag cacttttttt cgtttctaac gattttctaa
    67981 cgtttttcat tataaaaatt taagattggg aaaaataaag tcattgttgt cccttttcct
    68041 tcagttgatt cagccgtcaa atggatacct aatttttcgg ccagattttt tgctaaataa
    68101 agtcctaatc ctgttgaatg tgttttgcta agtcgaccat ttctcccagt aaatccctta
    68161 tcaaagatcc gtttcaagtc ttccgctggg ataccgatcc ctgaatcttt aactgaaagg
    68221 ctgactcctt gcgcttcctt ttctatgctc acaatgatgt ttccgtgatc cggcgtatat
    68281 ttgatggcat tactaagcaa ttggttgaag ataaaagcga tccatttagc atcggtcaaa
    68341 acagtatgat cctcaccaac gatctcgtag cgaatatttt tttggataaa ataatttgcc
    68401 tgactgcgta tcacaggctg aatgattcct tttagtccat attcttggat gaggtagtcc
    68461 cgcgagaaac tgtcgagtct tgcataatac aaaacttgtt ctacgtattc atcgattttt
    68521 gataattcat tttctagtaa tgtatacttt tgatcgtcaa tatcgaactc gatcgaacga
    68581 actagcaatt tagaagcgga aagtggcact ttgatttcat ggacccatga gtcaatataa
    68641 tctttttggt cttgttgatt actgattgct gattgcatta cttcttggtg ttcacggatc
    68701 agctgattga tatattcttc taccagtttt tcttcttctg tcctcccacc actcaaataa
    68761 ttttgcaaag gggaagtttt ttgtatgtcg gctaattttc cccaccatct tctcttgctc
    68821 aagtaaccac ccagcagata aaaaatcaga aagacgccct caatcaaagc taaataagca
    68881 attgtgctca aatcaacttt gatgtttggc gccagccaca tcacaaagat cgtcaatgca
    68941 ataaaaaaca gccatcccaa gatcaatgtc cactgatctt tcaaatattt aaaaaaattc
    69001 atcttaaccg ctcatccttt cagggaacga tatatccctg tcctactttt gtttcgatat
    69061 atccttggat acctgcctgt tcgatttttc ggcgtaaccg attgatgttg actgtcaatg
    69121 tattgtcatc tacaaatcgt tcgtcatccc acagtgctcg cagcaatttt tcccgactta
    69181 agatctttcc attgtgcttc atcaaaataa ataatagacg atattcattt ttgctcaaat
    69241 caatgatctc tccgttgatt tccatacttc cgttgtcaac attcaacgta atgccattgt
    69301 ggctcatcat ttcactagat aattctgtgt agttgtaaga acggcgaagt aatgcattga
    69361 tttttgcaat cagtacatcg atttggaaat gttttgtcac aaaatcatct gcccccatgt
    69421 tcatagccat gatcatatcc atattcgtat tcctgctgga gataaaaatg atcggtactt
    69481 tcgatacttc acgtattttt tgacaccaat aatagccatc caaaacggga agattaatat
    69541 ctagtaatac aagctgtggt tcttctcttt caaagtctga gaacacttga ttgaaatcgg
    69601 tcgttccaaa ggtttcaaat tgccatttct caagttcctc catgatcaat tgtcgaatga
    69661 tctcttcgtc ttcgactacc atgatttttg ccataaaaaa tccctccatc tttcttcttg
    69721 ctactacaat atcaaagaag cccttgtgaa acaagttggc ttacctggaa aatgtcattt
    69781 tagcaaacgt taaaaaaaac tggaaatatg cgatttaatc gcgtttgtct cttccaagca
    69841 gcttaaattt attatgttat tcttaataat tggtctatta tctgttattt ttctttcgtt
    69901 gtttttgtct tttaaatttt cgataacacc aataaccgaa aagcgttagc actagcaata
    69961 tacctagaag gagtataagt aatcgataaa gatggtattt ttttgtctgt tctatctttg
    70021 aagagacttc ttctgtaaag ggaactcgtc ttcctgtcac tagtaatcgg tgagtgttca
    70081 cggtgtaagg tgtacaagtg ataagtgtga ctagatcctg cttttctcta attgctaatg
    70141 tatttgtttt tgttggaagg acaacaattt tctcaacgac ttcataagcg agcatccgac
    70201 catacacttc aagatagaat cggtcatctt gctccatttc ttcaagatcc gtaaagagtt
    70261 ttttctcagc aataccgcta tgggcggtaa tcacggaatg tgtactctct cctccagttg
    70321 gaaaagaggt gccttgcagg actgtcgctc ctctatctaa caaaagatca ttcgtttcat
    70381 caaataaagg caagctaaca ttgattttcg gaatatagat ggctccgatc atatgttgtt
    70441 cgtaatattc ttttcctgga ttttggacat ttctaaccgc ttgctcaaaa ggatctttga
    70501 cttgtcccat tcctgggatt actgatgtat gagcaagcgt ctgatttttc ttttcatgca
    70561 ctgctaattg ttgctcatgt ttttcttctt tatcgcgttc aagctgcttt tgataattct
    70621 cgatccttct ttgatccaaa taattgctga gagcatctgc taaaaatgga tatgtaaaaa
    70681 ctgcagctcc ggcaagaaac atcactgcca taaataattg taataaaaga ctgatttggg
    70741 tttgaggtct attacctatt ttctttttca ttttcttcac cttcttattt aaaaaaactg
    70801 cagcaacctt tataaaaccg attgctgcag cttatttttg ttgcttatac ttcagacttc
    70861 attttagatt tacggtacca gctgtacgct ccaatcatca aacttattcc gattagtaag
    70921 aatgccaaga gcccgttccc accagtagca ggaagtgacc cgcgtttcat attcggtact
    70981 ctttctggcc ctggattttc tactcctacg atctgaattt cttcattata gcttccataa
    71041 gagatgataa attcagtaaa ggctgcctca cctgttggaa gtacataacc ttctggcgcc
    71101 atggtctctt tcatttgata ggttccataa tctaaccctt gaacctcaaa gtatccattt
    71161 ccatctgcga caaattctgt tgcttgtccg cttgttgccc actcaattct atctgctcct
    71221 gattcataaa cagctaaagg cgactcccct ttataaaata ttgcgtattc agaacggtct
    71281 tcattccaca attcgaatct tgcatcttta agcaattcac tgcttgatgc atcatatttt
    71341 tcaaactttc ttccacctgt tgtgactttc tctggcggct ctactccttc ttcataatca
    71401 aattcatcat ttcgtccgat ttcaataacc gctgtgttgt tatggaaatc atccgcttct
    71461 agttctgtgg aaaccttcaa attatacgtg atcgttaaat ctcctccacg tgcatctgct
    71521 aatctaccta aagtatctac tttggctact ccattttctt ctgtcaaaat cgtcacgaca
    71581 aacccgttgc ttactacttc tactatataa tcttgtcctt ttgttaaaat cgtctcgccg
    71641 gctcgcactt ctatttcctg atcataataa gttagaccaa ctgtaggcgt atctgtgatt
    71701 ttgtaatttt tgataacagc gcttccgttt tcaaggacag aatcgatgaa ataaggaata
    71761 ggtgctgtga tcgtgtaaga agccgttttt cctctttcta gatcaatata agaaatcgtt
    71821 tcttgttctc cagcttcatt aataatcgtt acttgtctaa ggtcgctttc ctctacattc
    71881 atctgtttat ctgcttctct gatttcgttt ttcggataca aatgcacatc tgtattgtat
    71941 gtgtctttcc atgtagaacc atcccacacg ccatccacca tatcaggcat catcactggc
    72001 atcataacaa ccattggaga cgcgattctg gaaatatgag ctggcgaata agtttctaag
    72061 aaaagataga ctttatctct agaagaaggt gcttcttccg tcacttggac ggtagagaat
    72121 accgcttctc cagcttcatt cgttgtttgt ttgtcaatac ttgtcagtcg atattttaaa
    72181 aaccaacttt ctgtgtgccg tttttgaatc cattcaatcg cttcggcaga attaagaccg
    72241 tcttctcgtt ccggtgttaa aggattatct cgaatcaaat cgtaatatac ttccgttacg
    72301 tcaaacaaat caaaatcgac tcctggaata ttttcttcac caaaatccgt agaaaccaat
    72361 ccgctattcg gtcgttcttc cggaacagat gagaaacctt ttttgtgtaa tgtaatcgtc
    72421 acttcacttg gtttttgtgc gacttcttcg gctttgacta gttttccgtt cccgaaaatc
    72481 cctattcccg cagtaacgag taacagtaca ctcattcccg tgacaatcat ttttttattc
    72541 atttttttct ccccgttctt tttttattaa taaaacagca cctaacaata aaagaattcc
    72601 tagtaaagaa atcaacgttc ttgcttcatt cgtttgcggg aatacggacc attttcctga
    72661 ttgacctgga ttgcttggac cactcggctc tttcggtttg tccgttgttt cttttacggt
    72721 ctcgttataa acacgtggtg ttgcggattc ataggcagag actggaactt tcccggattc
    72781 taattcagcc atctcctgtc cgttaactac tacatattgt ggttggcctt ttgcatccac
    72841 ccaaaattca gggatgatga cctcgattct cttacttgct tcatccatct cgtaaccttc
    72901 cacacctttt aattcttcaa aataataggt gccagaaggc aagaaacgtt gtcctgtcgt
    72961 aacaaggccc tctttatccg aaatgaattt gcttacattt ttgtcattca aaggatcatt
    73021 gtctgctggt ttgatccatt gatttttcaa gtcattagca ggagccatat ctaaataata
    73081 tttcccccct tctatcatct gatatagagc aaaaacagca ccttctaatg gttttccttt
    73141 ttcagttgtt cctctttgac gtccatactt gaagaagtat ggatctctta gataaccgac
    73201 atttttagga tagatatgaa tctcttgcag ttcctcggtt gattctgtcg ggtgataaat
    73261 tggcaaaata gcagcaattg ggatagctgt ctgatcgata tcaacatcca atccaacttc
    73321 tggatcaatc gattcttcga aaatcaaata aactgcatcc cgatcttggt ttttcttagg
    73381 tgctttgata cgtgcaatcc cgtctcctaa tccgccaacc gtatctttcc cagttgttac
    73441 cgaagtccct atttggacaa gcctttcttc tgtgattagc tgacggatat tgtttctgtt
    73501 cgtttcagcg atttgctgga cgaattcttt aggagtcatg ttttcagcag cttttttttc
    73561 atgataataa tcggtcatgt cgtaaatggc aaatgtcgct ccatttagtg gcaccgtctg
    73621 tgaaatgata tctgctgttt cccctgcttc ctcagagata gccaagccat cattttcatg
    73681 gtattcaaat tgatcgttat aatcgatatc tcgaatcatc cgtttatgca acacgaattc
    73741 cacgacatct tcccctgatt cttctgccga catcgcatgt ggaagaagga ctgctgcaag
    73801 cggtagtaaa acaagtaatt gaagcatcaa acacaacagc tttttcatta ccttgctccc
    73861 tcctttttag attgtctgac aaacaaacca taggctgctc ctgcaagcgc catgaagaat
    73921 gcagcaagca ggatatagaa taatcgtccg gatcctcctg tagcaggcaa cggattttca
    73981 ggatcgttcc cgacactaag ctgtaatctg attcgatttg tctccaaaag ttcatattct
    74041 aactcttgct gtagatcagg cgtctctgct tcttcgtttg gataatacga aatctcaact
    74101 tttagtgtac ccgcttcttt tcctggaact acccgatcat tttctatgtc aggttcttct
    74161 cgataactaa tttctaaaat aaagtaacct ggaagttttc tatagctgtc aggtgacttc
    74221 acttccttga tccgatagac cccttccaac aagtctgaag cattgaatag ggaagaatcg
    74281 tttggatctg gtgccaagcc tccctcgatg atttcatact ctcctgcact attttgtttc
    74341 tcaattgaaa attctgcgcc ttcaagacgt cggctattca tactgtcaat tttcaaaagt
    74401 tccaaatcga ttggcgctag ttcatcttct aaggttactt gtagtacacc atcgatgatt
    74461 tcatagcctt ccggcaaggg agcagtttcg tcttcgatga ccgtatcttc aatgataaac
    74521 ttaccttctt cattcagtgc aaactggaac acttgatcag atagccgata cccatttggt
    74581 gcgacagatt ccgagacctc atattcacca atagacagat gcagaggttg gtcgtaattt
    74641 aaatcgacat acttttctac tcctacggca cgagaataga agtatccgat cccaggcaaa
    74701 cgtttcgatt cttctggttc taacggatta ccagtgtatg ctcgatacag cgggaaggaa
    74761 gaatccccca ctttcctgat atcgaaacct gcaccatcta atgtatggcc ttcatggtct
    74821 aattttctaa ctcggatctc ccgataatca aacgtattgt aagcagtgaa tgctacccat
    74881 aaacgatcct cttcatctgt tgtatacgtg agatattgcc aattttcttc acctgtttgc
    74941 ttgagttgga tagtccctat agcattatcg taaagtcgca agatccatgt gtcattttca
    75001 tcaggttctt tgaaaccttc tgggttctgg ctctcaatga ttttgtattc tgcatagttg
    75061 gtagtttctt cactatcctt ataaacaaat gaatctggct ctccgattgg atgaataact
    75121 ttctcaccat ccacgattac atatttcccg tcttcatcta ctgaatagaa cgtgagtctc
    75181 cctttctctt cctctacttc gttcacacca gaaagccctt tcgctactgg atatccgatt
    75241 tccagtccgt taccatctgt ttcataaagt tcaaactctg cgccattgat tggcatatta
    75301 ctgccttcaa ttagtttatt gatattcatg tggattggct tgaattcatt tcgcatttcc
    75361 agtttgacat acaactcatc atactctgtg ccttctatgt taggctcttg tacaacagaa
    75421 agcttgtgat attctccttc ataataggaa ttcggatctt taccttccgg tccgccgact
    75481 ctcgaaccag atgtatattc atctacaagc tcgtagtgac ctaacatctc atcttcgttg
    75541 gctgcatatt ttttgatttg gaattgatac gtctcatcta ctaactgata acgtggtggt
    75601 ccagcgatct ctctgatcca aaatatgtcg ctgactgctc cagtttcatc tcctaaaatc
    75661 ggcatcttcg tttcaaagat cgctattccg tccgtggtag ttttacttgt ttcgattggt
    75721 tcggcttccc cactctctgg attttggtca tataatgcaa attcgactcc agccaacggc
    75781 tcgccatttt gacccttctt gctgacttgg aaattacggc ctttatgttc gtaacgaatg
    75841 gaagaagatg ggaaatacat ccgtccagta gtgatatcat tctcataatc ctccaggttc
    75901 tgaatatagg ccatattgtt cactgtgcaa aaatttccgt cttgagctcc cgcatcaagt
    75961 tttacttggt acttgatcct gaccatttcc ccttcaccta aagaaatcgg agaaaattta
    76021 taagcttggt tttcccgtcc gacatacgtt gtcggagtcg ccactacttc tggtggggct
    76081 tgtccatgac gttcttcatc ccatatttct ggctcttggt acttcatgcc gttttctcct
    76141 ggatctagat ggtaaaactg aatatctgcc gatctgccag ctccaaatgg tgagacatta
    76201 aaaccagttt catcataaag tgtggcttgc tggatcgttc tcttgaaggt agaagagata
    76261 tcctccaagg ctgtaacaat gtcattcttg ttgttcgcat tgtaatatcg cggtgttacg
    76321 ccatcttctt ctaaatcagc aatatttttc aatacatttc gtccaatagc atctagtcgt
    76381 tgtctcccgc taacgtttcc atcgattcct aaaccaatgg agaagatact tggcgggttc
    76441 tcttgatact tgtttttcag ccaatgatga taagcaactg tgttgatcgc agatgacttt
    76501 tcttgcgaag taggactgcc attcgtattg ttattagaag aaccatcacc aacccagtga
    76561 gtcgctttat tatctccttc ttttacctct ccataacgat agtgtacatt tacttcatct
    76621 tctggacggt taaagtcaga tgcataggta actggatgag taaaccctgc attagaagta
    76681 ttcccagaaa actcctcaaa atttctgaac aaaacgtcat tatcttcagc aatcttatct
    76741 tccatcacag tccagttgct ccaagctcca ttagtgctcg tacgataact tgactgaatc
    76801 ggtgcataac tgaaggtcgg tgtcccatct cccacaacga ttaggatttt ttctggattt
    76861 ctattttctc cgccattgtc tttatacaat gtttcatagc catttttaag ccctagtgta
    76921 agcggagttc ctccgattgg tgtacgattt aatgctgtat tctcacttcc cgtcaaacga
    76981 ttgatatcat ttgtcaatgg aaagatgtcc gaactgattt gctcatggtt attgatagct
    77041 gtactattat ggtaaaaatt caccataccg attcgaatat ccagactcgg gtcagagagc
    77101 agatctttac tcatttcgtt tactgcctca atcaacgcag catttttagt ttgactattg
    77161 gtcccagcgg ttaattcact catactcgct gacttatcta gaacaaaaac gatatcgatt
    77221 ggactgattt cctttttctc gcccccgatg acatctagat agacattgta aagggttgtt
    77281 gcatcttcag gatgtagatc agatgctgtg ctgcttggca gaacaggttc tacccatttt
    77341 ttgatgtacg ccccgttata atccaagtaa ctgttttcaa aattccgttc atttccccaa
    77401 agctgaacgg tttgagctgg aacgtttcta tcttcttcgc ctgcagttga tccattatta
    77461 gtagcatagt cgtaatttcg ccagttcgct cccccgtttg tataatcact atcatcgatc
    77521 aagttctctc cgtcatatgg cgagcctttg tctccttgat agcgttcatt gctttgtgtc
    77581 caatttccta acacttttgt atagtcattc gttgtaaact tcgggtagcg atgctgttcg
    77641 ttttcaactt ctccgctagg atagatatat tcataggggt cttgcgtagc tgttggccca
    77701 agacgctcca aaataccgtt gaataactgg cgttgaatgc gctggagtgc ttgaccgctg
    77761 ggtacgattg gttcgtccag cttttccatc tcattttctt cgctacgttg aatttcagcg
    77821 gaatcttctg tatcagtttc attttcttgt aattcttggt tatctattct ttcatcaacc
    77881 accacttgaa gaggtagtta cccttcgttc acatcgggga tcttttctgt ttcaaaaatc
    77941 aatgtgccgg tttctgcttc ttttgaataa acttttccga cataccattc ttgaccatcg
    78001 atcgtctcga cttttaggtc ttctccatct tcatcatagg aggatagacc tgttccacga
    78061 acgtttttta cggtaccaat cccggcggct gccgcatcga ttgctaaacg tattctacct
    78121 tcattggcac tttccttttt ttcaaaagcc agatgccatt caagggtttc ttctttttca
    78181 atatacttcc cttcaatttt tgcatagtcc tcatctaaga atacctcatc ctcctttgtt
    78241 tctgttgact cagcagctac atccagggtc gtcatatgat agactgactg gaaatatggt
    78301 ccaaatagca aactgacagt tactaactgc aaaagcttca attttaaccc tttcacatcc
    78361 ttatactcct ttcaaaaata tttgtcttct ttcacaacaa tcaacaaaac aatgcccatc
    78421 taattataat ttaatttaat tttaatttta aatcaaatga tatccttttt agttaaaaaa
    78481 caccaattat acaacattta ttattaaaat taaattataa aattttataa cgttctcatt
    78541 taacaaaact taagttatta agacaaatga ataaacaact acgctttcct cgaaacaaaa
    78601 aaataaagca caaatgcgca tttacgcact catgctttat tcgtacaatt aattcagata
    78661 acggcagcgc ataggatgcc aataacactt cctaaaatag ctcctcctaa aatgtcagta
    78721 ggataatgta aaagtaaaaa aatcctcgaa taagcgatca aacaagcaaa taaaaaggct
    78781 aatattcctg caactggact taattcgaac aacgcagcta ctgataaaaa ggctagcgct
    78841 gtatgtcctg aaggaaaaga agaagtcttc ggtttacttg tgtaaaggac aagccgacga
    78901 tttttttcat aaggtctttt ccgtcttgtc gtttttttga taaaaagcaa accaacaaaa
    78961 aaatagatca aactgccgat aagaatggct agaccatatt ctctagtatc aggtatcaag
    79021 actaaaacag cagcaaggag caaccaaata aaaccaccat tagagatatt actgataaat
    79081 ttcaaaaaat tgatttttcg actatccgtt ttccgttgct tggcgaactt gttgataata
    79141 ctatcatcga ttttagcaat caaacgcaac atgttattcc tcctttttaa gaaccttttc
    79201 ttgcgtacga tggataaaaa gcaggacttg aaaataaaac aagaaactga aacctaataa
    79261 agcaaaatag attggtcctg caaaccagaa tgcgacaaga aggatcaacg tgcctgccaa
    79321 atagaaaagc gcgcttttga aatcattaaa aaacaagaaa aatgcagtaa tccaagaagc
    79381 ttctttttgt tccagttgaa gcaagatttt gtaactaaag agaagcgcgc ttaatagaag
    79441 caaaaacaac gtagtataca tcaatgtata gccaattccc ccaccccaat agcggaaaat
    79501 ctgataatcg atcaatagaa gaagaaaata aacacttgct aaactatctt gctttccata
    79561 aagagagaag ttctcacgaa actttttcca gaatagtgaa ccgagctttt tctcttcatt
    79621 ttttttgtaa tgataaatca tatacagaac tgttcgactt gcagttccta atgtgaaaac
    79681 aggcaagacg cacaggaacc atagtagctg taaatggata agacgtggaa tccattcaat
    79741 gatttctaag aaataatcat tggctttttt accaatcgat cgattcatca tccttttgaa
    79801 cctcctgtca aatccatccc ttcaatgaaa taacgttgtg caaaaaagaa cagcaaaatc
    79861 gtcgggatca agacaagtgt tgctcctgcc atcagataat tccattgtgt cgttgcttgg
    79921 ttctgaaaaa cttgcaagcc aatctgtaac gtgtattttt cttgatcttg gatatataac
    79981 agaggaccta agaaatcatt ccaagctgcg ttgaaggaat tgatcgcaat ggtaatcaag
    80041 gcaggtttcg tcaatggaag catcaaatga ctccaaatat acaaatgatt cgctccgtcg
    80101 atttcagcag cttcgatcaa ttcattattg atcgataagt aaaattgacg catcagaaat
    80161 atattgaacg cattgccgaa gaacgatgga acgatcaggg gcaaataagt acctacccag
    80221 ccgatcttgg agaataatac atattgaggg atcatcgtta caaaccccgg gatcatcatc
    80281 gtagaaagaa ccaaagcaaa catcagcttt ttcccaggaa aatcaagctt cgcaaatcca
    80341 taagcaataa aagaatttga aaggacatta ccgatcacta ctagcacagt gatgaataat
    80401 gtatttcttg catagcgcca aaaaggaaag gcggcaatcg tatccagata gttttcccat
    80461 acgatttttt ctgggaaaaa ggtcggagga taacgaacga tttcttccat tggtttcaat
    80521 gaagtaaaca ccatccaaag caatggaatg atcaaaatga ttcctattac tgtcatgagg
    80581 acataactta gtattttttt tgtttgccga ttcacactgg tctttttgaa ataatccatc
    80641 atttgccgtc acctccagaa taatagaccc acttaggtgc aagcttcaaa ttgacaaacg
    80701 tcagaaccaa cacgatcaga aacaggatca ttgacatagc catcgcataa cccatatcaa
    80761 aagctacgaa cgccttgttc cacatatgca gattataaaa aagcaaagaa tttgcaggtc
    80821 cgcctgttcc atttttcgtc atgacataag cttcttgaaa aatttggaaa gaaccgatcg
    80881 tagaggtgat cacatcgtaa aaaataatag gagtgattaa tggcaaagta atacttttga
    80941 actttcccca aacgcctgct ccatcgattt ctgctgattc atataaagat ctaggaacat
    81001 tttgtaatgt agctaagtaa agtagcattg ctcctccaga actccatatt ttcatcaaaa
    81061 tcaacgcagg tttcgtccat tgtggatcaa acagccaagc tggtccaggg atatggaacc
    81121 agcccagaaa tgtgttgatc aatcctgcag atggagaaag cagctgcatc cataagatgt
    81181 agactgctac tcctgataag actgccggta aatagaaagc tgtacggaat acactgattc
    81241 ctttgatttt ttgattgagt actgtggcta aaaacacact gaaaatcgtc gtcagcggta
    81301 cattgaagat gacgaaataa acggtgttgt ataacgattt ccaaaataaa tcatcgtgaa
    81361 cgaacattct tttgaaattt gctagaccaa tgaaattcat cttggatgtc aaattataat
    81421 cggtgaaact accaataact gaaaaaagca taggccctag cataaatacc aagaacccga
    81481 taataaaagg cgagataaat aaataggccc atcttgcttc ttttttcttt cggatagata
    81541 aacgcttcaa attttcttgc ctcctctgta cctagacagt caaaaatgga ttattgattt
    81601 tgcttgacta agttttctac tgctttttgt gcatctgcca atccttcttt tggtgatttt
    81661 gttcctaaaa gaatctggtc aatctgttca ttcactaatg tcgtgtaatc cggagcatct
    81721 aaaggaactg gtgtgatcac cgtattttta aagttttcgt ccgccatttg atagatcatt
    81781 tttcctttat ccgttaggtt gtcattattc actaaattct cattggctgt cttgctcgcc
    81841 atgatatcaa aacttttttc gccgaatttt tcttgtactt ctggagaaga aagatatttg
    81901 atgaattcat aagaggcctc aggatctttt gctccgtatg gtacttccaa gacgaatccg
    81961 ccaccccacg accaatggcc tgaaccttct tctttttctg ggagctgcat cacgccaaaa
    82021 tcaaaatcat ccggtgcatt ttccatcaaa ctagagtaat aattgatatt ttgggcacgc
    82081 atggctacta atccggaaat aaatggatca gatacaccag acccaaattc ggcttctaat
    82141 ttattgatcg tatttttccc ataataatct tgccagtctt ggatccactc caaggcttcc
    82201 actttatttt tagtatcaat cttgactttt tcatctttgt caaaccaact agtcccgtta
    82261 tctgcgttta gcgcccatac atcagcccct aaattccata atggataaaa accgatgcgt
    82321 gtaaattctt ttccttcttt tttatctagt ttacgtgctg tttcttctaa ttcatcccaa
    82381 gttgtcggta gatcttgttc actgattcca gcttctttaa ataacttttt attataaaaa
    82441 atgacttgtg tatctgtatt gaatgggatc gcataaggat caccttcata ttctactgta
    82501 tcccaaagct gcggataaaa atccttagaa gtgtcttttt ctacatattt ggagagatta
    82561 gttgcttgct gtgcttctgc tctttgggca acggaattta tgtcctgtac aataacatcg
    82621 ggtgcatttc cagctgttat tgcagataaa gatttagtcc agatgtcacc ccatggctga
    82681 tacttataat ttacatggat ctcgttttgt gattgattga aatcctcaat gatttcttcg
    82741 atagcttctt ttcgtgcacc ggatccccaa aaggaccaga aatcaatatt ttttcttcca
    82801 tcacttgttt tttcagaaga atttgctgca cttgaactgg catcgcttgc attacttgat
    82861 ccgcatcctc ctaataaaaa caatgctgaa cttgccagca accctgtaaa caataatttt
    82921 ttcatatttt acctccaaat tttaatgtaa ccgatgccgg ttttaatata acgatatcat
    82981 tttgttctga aaataacaat ttataaggta tgattctaaa aaaattatta atgataccaa
    83041 tactttatat aattcgcgag cgctttcttt gaatttttta atctttcgta gcagaatgag
    83101 aatgtattaa aaatagatta ggaggaattt tgatgtttag acaccagaaa gaattgcagt
    83161 ttgaagcaaa accagatcgt ccgaatccat taatcgcgaa atatctgcag gagctgatcg
    83221 gcggccaata tggcgagatg agtgtagcta tgcagtacct gttccaaggc tggagctgcc
    83281 gaggagaaga aaaatataaa gatatgctga tggacattgc aacagaagaa atcggccacg
    83341 tggaaatgtt ggcgacaatg gttgctcgtt tattagaggg tgcgcctgtt gaagatcaag
    83401 aagcagcgat gcaaaaagat ccaacaatcg gtgccattat ctctggaatg aatccacagc
    83461 acgcgatcgt agctggctta ggacctcgtc ctgctgacag cgtgggcaat ccatggagcg
    83521 gtgcctatat cattgcgagt ggcaacttgt tagcagactt tagagctaat ttaaatgccg
    83581 aatcacaagg aagacttcaa gtagcacgta tttacgaaat gatcgatgat cgtggcgtaa
    83641 aagatatgct gtctgttctc cttgcaagag atagctatca tcaaaatcta tgggaatgtg
    83701 cagtgaaaga attagaagaa aaagaaggtt caatcttagt cccaagtact ttcccgcgtg
    83761 acaaagaacg aaaagacatt gcttatgact tctataactt ctcagaggga gaccaaagta
    83821 gtgaaggttc ttgggctagt ggcaaagcac tggatggcga aggcgaatat caatggttga
    83881 aagaacctaa gatcgaaggc gctgcaccaa aattagaacc agtaacacca aaaatgtatg
    83941 ggacacctcc attcaagaaa taaatatcta cccgtagaaa cacccgtttt ttgttccaca
    84001 cgctttgtga gcaaaactga ctaaagtcat taatcataac cacccttcaa aagggtggtt
    84061 ttctctagag ctataagctc aaatcaccgg ccagcgccta aagacgctgg ctttcatatt
    84121 ttatgttcaa gccatattgc ctttgccagt tttgcccacc tcttaaaagg tttatgtact
    84181 actccttagc ccttaaaagg atcgtcttac tctcgtacac tcagcttatc taacgcacta
    84241 tcatgttttt cttgttcttg aatgtacttt ttgatggtcg cttcattttg tcctactttt
    84301 gtcacatagt atccttccac ccaaaagtgt cgatacccaa atttatattt tagatttgca
    84361 caatctcttg atgatctcct gaatattggc tcgatattga ttataaatta tttttcttct
    84421 atactttggt gtgaatacaa tgtggtattt acacatctac tttgtacggg ctaaactatt
    84481 tccctttatt gctccacccg catagcaagt ggttttgtat ttcaatcgct cggcgcgctc
    84541 aattaggtct aaagacaata aatctaaaaa cccgctgctt cactgacaga aacaacgggt
    84601 tttcagaaaa aaatgaaatg aaaaagatct cttacggcaa tctattttat ttttttgatt
    84661 ttttataaat ggaaaatgct tcaagaagtc caagaaataa agccgtataa aaacaagaac
    84721 ctatgaaatc tttatttatt agatattcaa cagaaatccc gataacacta gccaacaata
    84781 tatttatcag aagtgtaaaa taaggatgct ttttatagaa tagaactagt gttgttttca
    84841 tagactctcc tttcttcata tttccaatta atcacaaatt cacggcatta ctagaaaaat
    84901 taaaggggcg cagaagtgga aaaatactct tcgactttcc ctacaaacca ggccatcttg
    84961 tgtttaataa ctataccaaa tctaaggtac ctctaaatct aaattccatt tgtggcggtg
    85021 acctccaatt tttaactctt ctatctccca tccagtatac ataaccttga tacttcgacc
    85081 acttatatat cgaacacaca aatacctatc cattgcagga gtactaccta acttagttgc
    85141 tacttgcatc taaataacag ctgaaaagat aggacttact cttagtaaag tatctgaact
    85201 attaattttt aaactatcat ttttatcctc aactacatgc acatctgttg caacttcact
    85261 ttctgtctca tccagataaa tgattaagga atcgggaatt gcaatatctt cagctgacgc
    85321 tggaatagtt gagctaaatt agtcatcata tctttattat aaaataacca acagcaaaaa
    85381 atacaatgaa aaacaaactt ggaactaatg tatcattaat aaatgttgaa aaattcagca
    85441 actcattact gtatgatttt agcagcccaa ccaacatata ccctataaaa gctaataaga
    85501 tggttaggaa tcctttagaa tttttactca ttca
//
LOCUS       DAZKPE010000005        72269 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000005 DAZKPE010000000
VERSION     DAZKPE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.005"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(56..1639)
                     /locus_tag="ACG930_000347"
     CDS             complement(56..1639)
                     /locus_tag="ACG930_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517541.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            1761..2345
                     /locus_tag="ACG930_000348"
     CDS             1761..2345
                     /locus_tag="ACG930_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517542.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            2356..2601
                     /locus_tag="ACG930_000349"
     CDS             2356..2601
                     /locus_tag="ACG930_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517543.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            2607..3329
                     /locus_tag="ACG930_000350"
     CDS             2607..3329
                     /locus_tag="ACG930_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517544.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            3460..4203
                     /locus_tag="ACG930_000351"
     CDS             3460..4203
                     /locus_tag="ACG930_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517545.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            4209..4574
                     /locus_tag="ACG930_000352"
     CDS             4209..4574
                     /locus_tag="ACG930_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517546.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            4590..5120
                     /locus_tag="ACG930_000353"
     CDS             4590..5120
                     /locus_tag="ACG930_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517547.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            5282..5590
                     /locus_tag="ACG930_000354"
     CDS             5282..5590
                     /locus_tag="ACG930_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517548.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            5721..6005
                     /locus_tag="ACG930_000355"
     CDS             5721..6005
                     /locus_tag="ACG930_000355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517549.1"
                     /translation="MTFLNSVFIDYVITTKRIGSYSSTYASLVPMLNSMSRFLKEREK
                     KELQYIKEIMPDFEMHEWQIALSDWKLANKVRRITPFQAKRFLRAMKFVQ"
     gene            6142..6942
                     /locus_tag="ACG930_000356"
     CDS             6142..6942
                     /locus_tag="ACG930_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517550.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            6979..7161
                     /locus_tag="ACG930_000357"
     CDS             6979..7161
                     /locus_tag="ACG930_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517551.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            7272..7589
                     /locus_tag="ACG930_000358"
     CDS             7272..7589
                     /locus_tag="ACG930_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517552.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            7592..7735
                     /locus_tag="ACG930_000359"
     CDS             7592..7735
                     /locus_tag="ACG930_000359"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517553.1"
                     /translation="MLSDLFILLIYLGVSEIIAYFLFVIANYGISSAIVQMFRLPVSE
                     LKK"
     gene            complement(7939..8418)
                     /locus_tag="ACG930_000360"
     CDS             complement(7939..8418)
                     /locus_tag="ACG930_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517554.1"
                     /translation="MTDKTSDLPKLAPKTSRVKRKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            8502..9875
                     /locus_tag="ACG930_000361"
     CDS             8502..9875
                     /locus_tag="ACG930_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFQ0517555.1"
                     /translation="MKKSKRKIATLLMLMVQFTGIAMSVITINPQVIHADGIATYDAQ
                     FNCTTEGSGSGTDSDGNDTGSGAVSGDVAKNIDDIYKFMNGEYGLSGATIAGILGNWK
                     QESGNDPRTVEGYYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVNWAKKNFGGA
                     WWTTEAQLDFMFKGDGGFVAILKDYALNASDDVVANAVAFHKNWEISADSESAVVAVR
                     GGNAKEIWKYMKSKGMDGAKDVSKINKIAGGTSTGGGSNNSSSSASGTVEDACATTDD
                     ANSGSGSMGKEGKINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQ
                     GQCTELTWAYMSQLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWA
                     VGDAGHTGVVIAVFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGK
                     AKFEIEK"
     gene            9898..10425
                     /locus_tag="ACG930_000362"
     CDS             9898..10425
                     /locus_tag="ACG930_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517556.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            10412..10975
                     /locus_tag="ACG930_000363"
     CDS             10412..10975
                     /locus_tag="ACG930_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517557.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLENLDSYVRAE"
     gene            11398..12135
                     /locus_tag="ACG930_000364"
     CDS             11398..12135
                     /locus_tag="ACG930_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517558.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANHQD
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            12252..13571
                     /locus_tag="ACG930_000365"
     CDS             12252..13571
                     /locus_tag="ACG930_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0517559.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKHGRKIRLVVKREVNKFRYCGD
                     IRKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGVVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEDYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRKQYEEEKEKTFKAIRWDWGRQREIYMSKLW"
     gene            13588..13740
                     /locus_tag="ACG930_000366"
     CDS             13588..13740
                     /locus_tag="ACG930_000366"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517560.1"
                     /translation="MDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGIEF
                     KISDLQ"
     gene            14027..14758
                     /locus_tag="ACG930_000367"
     CDS             14027..14758
                     /locus_tag="ACG930_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0517561.1"
                     /translation="MENSFKNKALYHQLVDLLKKRMESGMIPHDKLPSERELTAQYGV
                     SRTTVRLALQELENTGYIYRRHGKGTFVSDIKTAAADLAGAYSFTEQMKSLGRHPETR
                     ILSFEKMEADKFIAQRLNLPLGEAVFKLSRLRIADREPLMIEDSYLPVKFFLSLDDQL
                     LRSKPLYDLFSEDFKQTVRLADEELYASIASKDDAKQLMIPEGAPVLHLVRQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            14771..15943
                     /locus_tag="ACG930_000368"
     CDS             14771..15943
                     /locus_tag="ACG930_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0517562.1"
                     /translation="MFTIEKEKLEQMGAEITTREIRQQPELWKETIDLYQSAQGELEN
                     FLTEVQKQAKGQRTRVIFTGAGTSQYVGDTLVPYLRKHGDRQAFSFESIGTTDIVAEP
                     EEYLIKEEPTLLVSFARSGNSPESLAAVEIANQVVDTIHHLSITCAKEGKLAQISQAD
                     SKSFLFLMPVRSNDDGFAMTGSFSCMTLGALLTFDQTALAEKQNYVETLNALGNEVIA
                     REHDIEEIVALDFERIVYVGSGSLAGLTREAQLKILELTAGKIATVFDSSMGFRHGPK
                     SFINEKTIMFGFVNNDPYTRDYDLDILEEVHEDEIASGVFAITQPGKRNFSGDTFEFA
                     TGTSLLPDAYLALGYVMVAQTVALLTSVKVANTPDTPSPTGTVNRVVKGVTIHDYK"
     gene            15966..16973
                     /gene="lacD"
                     /locus_tag="ACG930_000369"
     CDS             15966..16973
                     /gene="lacD"
                     /locus_tag="ACG930_000369"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFQ0517563.1"
                     /translation="MLTLTTGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEP
                     TDKHIEHFKELVSSELTPYASSILLDPEYGLPAAKVRHADAGLLLAYEKTGYDATTPG
                     RLPDLLADWSVLRLKEQGADAIKFLLYYDVDEDPAINHQKHVFVERLGSECAEEDLPF
                     YLELVSYDAQISDAGSFDYAKVKPHKVNDMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     GTGEIAYTKEEAANYFLEQSQATDLPFIFLSAGVSTELFQQTLVFAKEAGSTFNGVLC
                     GRATWKNGVKPFIESGEAAARDWLQSEGRENIESLNNMLKQTASSWHDKVQVAEEEAV
                     N"
     gene            16985..17947
                     /locus_tag="ACG930_000370"
     CDS             16985..17947
                     /locus_tag="ACG930_000370"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HFQ0517564.1"
                     /translation="MIVTVTMNPSIDISYPLEKLKLDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGFHGAYISEELKKAGIKQAFTEIQEESRDSIAILHEGNQTEI
                     LEAGPTVSEAEQQAFLENFQELVKEAEIVTISGSLAKGLPLNFYQRLVQLAEEQVVKV
                     LVDTSGESLRQVLTGEHKPFLIKPNLEELEALLGQPFSIDDLEELQSALAQPLFTGVE
                     WIVVSLGKDGALAKYRDSFYRVTIPTIKTVNPVGSGDATIAGFAYGLSQKMSVTELLK
                     LCMAAGMANAQEVRTGHVNLANVDMHFEEINVRKASRTRSAFEQ"
     gene            complement(18178..18888)
                     /locus_tag="ACG930_000371"
     CDS             complement(18178..18888)
                     /locus_tag="ACG930_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0517565.1"
                     /translation="MVIPKYQIIKDELKQQIISGKFENGDKFYTEAELAEMFSVSSIT
                     VIRALNDLVKDGFIVRHQGRGSFVSRARKGKIVEFSDIELFPISNDQVQVLSITRGND
                     PVYLSKLELPDTAFYYCIKRLRKAEETPYIYQQTYLPEQYVNPNYQELSYYNSIYQRF
                     KLDYNIHMNEEDFTETNEIKFPTPSDAAKLLEISADEPTVLQVRVTKRRDTQQMLEYV
                     ESYKKWNFYKIELVSKNN"
     gene            19059..20837
                     /locus_tag="ACG930_000372"
     CDS             19059..20837
                     /locus_tag="ACG930_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase family protein"
                     /protein_id="HFQ0517566.1"
                     /translation="MKTFEIKEDFLLNGEAFKIMSGAIHYFRIDPADWYHSLYNLKAL
                     GFNTVETYIPWNLHEPKKGEFHFEGILDLERFLSIAKELELYAIVRPSPYICAEWEFG
                     GFPAWLLNEDTRIRTNEIGYLKHVADYYDVLIKKLVPHQLSNGGNILMIQIENEYGSY
                     GEEKDYLRSVRDLMINRGITVPFFTSDGPWRATLRAGSMIEEDILVTGNFGSKAEENF
                     ASMQSFFDEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAEELAEAVKEVLIRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLNEQGNPTEKYFAIQKMIHDTFPEIQ
                     QMEPLTKNTMEVKGIHLRNKVSLFSTLDTISQPVKTTYPETMEMLGQNTGYILYRTSI
                     KKDAEEERLRVIDGRDRSQLFLNQKLQATQYQTQIGEDIIVPMTEETNQLDILIENMG
                     RVNYGHKLFADTQNKGIRTGVMADLHFLTDWSQYCLPLDSCEAVDYSREWQPEQPSFY
                     RYEVVLDEVEDSFIDLSNFGKGVVFVNQVNIGRFWEVGPTLSLYIPKGLLKEGNNEIV
                     IFETEGTFQPEIQLVKKPLYKEMKEG"
     gene            20840..21319
                     /locus_tag="ACG930_000373"
     CDS             20840..21319
                     /locus_tag="ACG930_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFQ0517567.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAQNDIEK
                     SGLKLATPAGVKLSVLPIEKAANNILAGKYDSQRLLIIARKPDRLLKLVELGVPIEEI
                     NVGNMSQTDETRSITKSINVVDQDVEVFNQLHAKGVRLIAQMVPSDKAEDFMNLLAK"
     gene            21332..22228
                     /locus_tag="ACG930_000374"
     CDS             21332..22228
                     /locus_tag="ACG930_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0517568.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGAIPWSFSRMIPVFLAL
                     AFGGGLVEKVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGVVKNFEGIFNSLPMLAIALIGFALAAISYKNGQMIPS
                     SPAPKEVASNDSDEGEIEDDEI"
     gene            22215..23024
                     /locus_tag="ACG930_000375"
     CDS             22215..23024
                     /locus_tag="ACG930_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0517569.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEIMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIGGKDTVSGMKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKFSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSALGVISK"
     gene            23062..23466
                     /locus_tag="ACG930_000376"
     CDS             23062..23466
                     /locus_tag="ACG930_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0517570.1"
                     /translation="MGKQLVLVSHGLFCEELKKSTEMIMGPQESIHTVSLLPAESAED
                     FRAKFEAVIADLDDFVVLADLMGGTPCNVVSRMILEGQAIELYAGMNMPMVIDFINSE
                     LIGTELALVESATSNICHVNERIIGDDDDEDE"
     gene            23610..24203
                     /locus_tag="ACG930_000377"
     CDS             23610..24203
                     /locus_tag="ACG930_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517571.1"
                     /translation="MDFNEKLKQLRQNKQWTQEELAERLFISRTAVSKWESGRGFPSI
                     DSLKAISQVFDISIDELLSNSELLSIAENEQQQQRKNFQHLLLGISDCMVGLLIVLPI
                     FGQAQGNHIAFVSLWQLSQETIIFKLIIFSFVILTMLFGIFELAFSRREQRIIGSVSL
                     ILSLFGVLLFIMTRHPYPATYVLMLLAVKGISLLNSR"
     gene            24312..24971
                     /locus_tag="ACG930_000378"
     CDS             24312..24971
                     /locus_tag="ACG930_000378"
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0517572.1"
                     /translation="MKIAKKQLETAIGLLIVFILYTISLSLFDVQKIGPQHSEVGFST
                     INQYVFQKIGTSEFWYQVTEILGIFPLIIVGYFALRGFFQLYTRKKLLLVDKEILALG
                     FLYAGVAACYVLFEKVIINYRPILVDGQLEASYPSSHTFLAITVLLSAFYVLRKETGT
                     GKAIIAYVSLVVMIALVIGRFLSGAHWGTDIFGGILLGLTLASCYLAGIESSSKQKKE
                     R"
     gene            complement(24992..25064)
                     /locus_tag="ACG930_000379"
     tRNA            complement(24992..25064)
                     /locus_tag="ACG930_000379"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25029..25031),aa:Thr,seq:ggt)
     gene            complement(25182..26330)
                     /locus_tag="ACG930_000380"
     CDS             complement(25182..26330)
                     /locus_tag="ACG930_000380"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0517573.1"
                     /translation="MSKHKHQKRKKNKLTLVFPLFLILLAFSGMYAEHSYPEHHATKK
                     SSTPATKTTTDLTNQQPIEPKNATSAGIEQLLVEKNFSGTVLVFQHGQVILNKAYGWK
                     DQARRIHNTIHTQYCIGSVQKGQTAYLIMQAVKSGKISLEEKLSTFYPQISNSEKISI
                     KDMLNMSSGLRIDEKKIAALNTTDPQKILSETIRQTTVAANSSYSYQPVNYVLLAGIL
                     EQVYHTDYSTLFDKLLRKPMKLKETSFYSETNNQQALSYSESSSGPVYAPTTVSSYAD
                     ELGTGNVFMSGEDLYSYFQDLYQDKFLTTQERAALWQSYPGEKYASGIYNMTNNYHSR
                     GVKARFEALVDFSKDGQNGIILLSNVWTQPKGYNDIVSKLYKQVVAGS"
     gene            26461..26534
                     /locus_tag="ACG930_000381"
     tRNA            26461..26534
                     /locus_tag="ACG930_000381"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26495..26497,aa:Asn,seq:gtt)
     gene            complement(26569..26985)
                     /locus_tag="ACG930_000382"
     CDS             complement(26569..26985)
                     /locus_tag="ACG930_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517574.1"
                     /translation="MNKKRKLSVLITLVSILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETVTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            27377..28624
                     /locus_tag="ACG930_000383"
     CDS             27377..28624
                     /locus_tag="ACG930_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0517575.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETAKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTETDTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            28894..31284
                     /locus_tag="ACG930_000384"
     CDS             28894..31284
                     /locus_tag="ACG930_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0517576.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     KFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNTLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            31333..33168
                     /locus_tag="ACG930_000385"
     CDS             31333..33168
                     /locus_tag="ACG930_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0517577.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            33243..34100
                     /locus_tag="ACG930_000386"
     CDS             33243..34100
                     /locus_tag="ACG930_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0517578.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            34090..35199
                     /locus_tag="ACG930_000387"
     CDS             34090..35199
                     /locus_tag="ACG930_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0517579.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            35538..36338
                     /locus_tag="ACG930_000388"
     CDS             35538..36338
                     /locus_tag="ACG930_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517580.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            36444..37232
                     /locus_tag="ACG930_000389"
     CDS             36444..37232
                     /locus_tag="ACG930_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517581.1"
                     /translation="MSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(37249..38694)
                     /locus_tag="ACG930_000390"
     CDS             complement(37249..38694)
                     /locus_tag="ACG930_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HFQ0517582.1"
                     /translation="MLGVILMMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFD
                     FIYPIVESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYS
                     FEDPIPHFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANA
                     NKHKFTKEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESG
                     YYVKGEREKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRV
                     VADAGYKTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPL
                     LFSTITRDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTA
                     LNREIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLW
                     KTKKPMAFYFKIMQRLTKRSGLITNSFLSTI"
     gene            38997..39866
                     /locus_tag="ACG930_000391"
     CDS             38997..39866
                     /locus_tag="ACG930_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFQ0517583.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            39886..40233
                     /locus_tag="ACG930_000392"
     CDS             39886..40233
                     /locus_tag="ACG930_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517584.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            40246..41508
                     /locus_tag="ACG930_000393"
     CDS             40246..41508
                     /locus_tag="ACG930_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517585.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            41588..42964
                     /locus_tag="ACG930_000394"
     CDS             41588..42964
                     /locus_tag="ACG930_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFQ0517586.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            42961..43590
                     /locus_tag="ACG930_000395"
     CDS             42961..43590
                     /locus_tag="ACG930_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517587.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            43609..44088
                     /locus_tag="ACG930_000396"
     CDS             43609..44088
                     /locus_tag="ACG930_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517588.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            44647..45246
                     /locus_tag="ACG930_000397"
     CDS             44647..45246
                     /locus_tag="ACG930_000397"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFQ0517589.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIHFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            45262..45738
                     /locus_tag="ACG930_000398"
     CDS             45262..45738
                     /locus_tag="ACG930_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517590.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            45755..46657
                     /locus_tag="ACG930_000399"
     CDS             45755..46657
                     /locus_tag="ACG930_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517591.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQANNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            46730..46924
                     /locus_tag="ACG930_000400"
     CDS             46730..46924
                     /locus_tag="ACG930_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517592.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            47029..47457
                     /locus_tag="ACG930_000401"
     CDS             47029..47457
                     /locus_tag="ACG930_000401"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517593.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNKETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            47692..48279
                     /locus_tag="ACG930_000402"
     CDS             47692..48279
                     /locus_tag="ACG930_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517594.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            48279..49178
                     /locus_tag="ACG930_000403"
     CDS             48279..49178
                     /locus_tag="ACG930_000403"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFQ0517595.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            49178..50092
                     /locus_tag="ACG930_000404"
     CDS             49178..50092
                     /locus_tag="ACG930_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517596.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            50144..50359
                     /locus_tag="ACG930_000405"
     CDS             50144..50359
                     /locus_tag="ACG930_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517597.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            50545..50685
                     /locus_tag="ACG930_000406"
     CDS             50545..50685
                     /locus_tag="ACG930_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517598.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLTELGRSRPSSI
                     GG"
     gene            50806..51210
                     /gene="tnpA"
                     /locus_tag="ACG930_000407"
     CDS             50806..51210
                     /gene="tnpA"
                     /locus_tag="ACG930_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFQ0517599.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            51227..52375
                     /gene="tnpB"
                     /locus_tag="ACG930_000408"
     CDS             51227..52375
                     /gene="tnpB"
                     /locus_tag="ACG930_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HFQ0517600.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            52641..53684
                     /locus_tag="ACG930_000409"
     CDS             52641..53684
                     /locus_tag="ACG930_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0517601.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            53857..54081
                     /locus_tag="ACG930_000410"
     CDS             53857..54081
                     /locus_tag="ACG930_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517602.1"
                     /translation="MNQRRRKRLEEISERLSKLKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            54084..54341
                     /locus_tag="ACG930_000411"
     CDS             54084..54341
                     /locus_tag="ACG930_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517603.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            54558..55433
                     /locus_tag="ACG930_000412"
     CDS             54558..55433
                     /locus_tag="ACG930_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517604.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            55443..56237
                     /locus_tag="ACG930_000413"
     CDS             55443..56237
                     /locus_tag="ACG930_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517605.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            56266..57384
                     /locus_tag="ACG930_000414"
     CDS             56266..57384
                     /locus_tag="ACG930_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517606.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            57417..57737
                     /locus_tag="ACG930_000415"
     CDS             57417..57737
                     /locus_tag="ACG930_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517607.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            57992..58681
                     /locus_tag="ACG930_000416"
     CDS             57992..58681
                     /locus_tag="ACG930_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517608.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            58718..58885
                     /locus_tag="ACG930_000417"
     CDS             58718..58885
                     /locus_tag="ACG930_000417"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517609.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            58905..60539
                     /locus_tag="ACG930_000418"
     CDS             58905..60539
                     /locus_tag="ACG930_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517610.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDSHVNMSLTIKRIYDLLYVYKH"
     gene            60511..61737
                     /locus_tag="ACG930_000419"
     CDS             60511..61737
                     /locus_tag="ACG930_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517611.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            62587..62982
                     /locus_tag="ACG930_000420"
                     /pseudo
     CDS             62587..62982
                     /locus_tag="ACG930_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            63060..64099
                     /locus_tag="ACG930_000421"
     CDS             join(63060..63557,63560..64099)
                     /locus_tag="ACG930_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611651.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HFQ0517612.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTLKKADSKKQQVFLE
                     ETFPSLKKLLNSDIDHLLFEDETMIRDYQAIGCTWFLRGHQRKIPTYGQHKGVKLIGT
                     LDYETGRIICTEEGAYDAAAFLRFLERTLREYPTGKIVMVLDNALIHHAKLIQSFLEE
                     NARRLALIFLPPYSPQLNLMEGVWKWLKESVINNVFFDHVQKIKQSVRGFLADVNERP
                     LEVIDRLCVRM"
     gene            64112..65050
                     /locus_tag="ACG930_000422"
                     /pseudo
     CDS             64112..65050
                     /locus_tag="ACG930_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            65043..65390
                     /locus_tag="ACG930_000423"
     CDS             65043..65390
                     /locus_tag="ACG930_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517613.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            65387..65569
                     /locus_tag="ACG930_000424"
     CDS             65387..65569
                     /locus_tag="ACG930_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517614.1"
                     /translation="MNIIKKYEFGYITYEQLIEELWGYGQQLINEVGIDCFCFYIESG
                     AGYHKNRYYIFPYPPK"
     gene            65705..66325
                     /locus_tag="ACG930_000425"
     CDS             65705..66325
                     /locus_tag="ACG930_000425"
                     /inference="COORDINATES: protein motif:HMM:NF037736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0517615.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFFRNSN"
     gene            66568..67128
                     /locus_tag="ACG930_000426"
     CDS             66568..67128
                     /locus_tag="ACG930_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HFQ0517616.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            68017..68784
                     /locus_tag="ACG930_000427"
     CDS             68017..68784
                     /locus_tag="ACG930_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFQ0517617.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            68810..69355
                     /locus_tag="ACG930_000428"
     CDS             68810..69355
                     /locus_tag="ACG930_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517618.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            69356..69922
                     /locus_tag="ACG930_000429"
     CDS             69356..69922
                     /locus_tag="ACG930_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517619.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            69937..70185
                     /locus_tag="ACG930_000430"
     CDS             69937..70185
                     /locus_tag="ACG930_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517620.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            70204..70443
                     /locus_tag="ACG930_000431"
     CDS             70204..70443
                     /locus_tag="ACG930_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517621.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            70460..71044
                     /locus_tag="ACG930_000432"
     CDS             70460..71044
                     /locus_tag="ACG930_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517622.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            71151..71432
                     /locus_tag="ACG930_000433"
     CDS             71151..71432
                     /locus_tag="ACG930_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFQ0517623.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            71422..71763
                     /locus_tag="ACG930_000434"
     CDS             71422..71763
                     /locus_tag="ACG930_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0517624.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT        26098 a        10492 c        14737 g        20942 t
ORIGIN      
        1 agtttaattt gaaagtaaat atacgctata aaagtgcatc ttgtgttata aaaaattatt
       61 ttattttgtg aacataattt aacaattctt tctcggaatt gatttctttt cttaaatagt
      121 cttcagactt attaataata ttatctatta tgtctagata catatcactt ttcgattcag
      181 ctaattcata cagttttttt aattctttat cctttaattg aaaaccctga tccatagtca
      241 ctgcatttgg atatagaagc ccactataat gtttacgtaa attcacttgg aatttctgat
      301 tataaaagtc taacagatta gaaataaaag gcggaaaatt actgtttttg taaaattgat
      361 tatttccatt taggttgtat agtaatttgt taaattgctc ctgatttaat ttattgtaaa
      421 tccatggtaa tacttccata tccttatctg ctaacctgaa tgaactagca tcggtaagat
      481 gttcgatcat aaaatctatg aacatctctt tttcaccaaa atataaatat tgattatata
      541 ttgtttctaa tgttgaagat ggtagcgaag aaactctcat tttttgctgg agtataggat
      601 caactagact atttaagtga ttttgtaatt cttcattgtt gtttcctaga actgcaaggg
      661 aacgtaaacg gtagtaatat tctatttctg ttagtacttg ttgtttcggt ttaaaatcat
      721 ttattgatat ttgtaaattt tgaattgtct cgtctgaaaa atcatgttgt aattctggat
      781 gggtagctat aaaagtaagt aaaaagaacc cttttgtata cgtgatctgt tgattttcac
      841 caagtgattt attaatttcc tctcttgatt cagctgtgaa cctatacttt gcaatttctt
      901 tttttagaat atttaaatag aattctttat tatcaaaaat tagggcatta agtagtctga
      961 aagtactttc cctatctcta tctgcttcct catttccata agataattga aaaacaaact
     1021 taaaggctgt cttacatagg ttttctttgg ctttttcgct tagtttattt agatagctat
     1081 tttttagtgc agagtgaaat tcttcaggtg taacagacat agcatgtatg cgacttgcat
     1141 attgtataat ttcgatcgtt actttttttc ctaatattgg attttttagg aatataattt
     1201 cataggactt ccgtataaca tcctgacaag tttcttttgt tatatctctt aattcccaag
     1261 tattaccgtt gtaagtgact acaggatgag ctgaataatt tctttgatcc ttaatatatt
     1321 ttaaatcctc atattcatag ctatcaatta gctcagttga actataagct ttttctagta
     1381 gttccatttc ccattttgga gagtttggat cactttttct tagtctagct atatcttcta
     1441 aaattttctt agaagtatta tcctcgtaaa tatttgctaa atcagataat ttatcaatta
     1501 aatctaaaat aagcgcactg taattgacag ctattgcaga acgataattt ccctgataaa
     1561 aactacttct aacttcttct aataatggaa taattctagg atttttaact ttttttattt
     1621 catcatctaa tataaacata taaatctcct ttttttattt gtatgacaag tttaccataa
     1681 aaaaaaatta aaaagcgaga catatttatg ttgttgtgtt atcataataa cataaatatg
     1741 tagagtgaga tgatgaaaaa atggatttga aacaatcgtt ttacatctgg ttatatcctg
     1801 ataatcctat gtcaataatg gctgatattt ttgtagttag catcttattg tatttatttt
     1861 atctaatttt ctttcacaat ttaatcgggt acatgattct tgattggaaa ggaatgttcg
     1921 atatagaaag aaaaccattt gctaacaatc aaacctatac cgtcttcgaa agtggagatt
     1981 gggaagaaaa tgaagttgat gtgatccatg aaattggatt agctttatca ggaatacaag
     2041 atgctgatgt tttggtatca atgacaacgg atactggata caacgcttat gaggtatttt
     2101 atcttatgta ttttatatgg cgtgatggtc aagaaattat caatggtcgt gctgaaaaaa
     2161 caatcaattc taatactgaa atttcttttt gtatgggtga aggggaaatg attgtatata
     2221 aagatgggtc agcaaacatt aaaacagcct ttggtgatat tgaaacaagt attaaggaac
     2281 ttagggaata tgtgcagaac ccatataatt ttcaatattt agcaggaaga ataaatttag
     2341 tttaggagta aaaatatgaa aaaaattata aatcaaccaa caaatcactt gataattgaa
     2401 ggtgttattt tcgtaacaat gtattttact gtaggaaatg gcatctcaaa tacaatcatt
     2461 caaaaaaatc cacaatacct attatttagt ctttatgctt ggattgtaca aatggtttgg
     2521 gtttccatat tgatgctgtt gttttattgg atagtacggg ttattctttt attgttaaac
     2581 aaaagaaaaa aggataggtg aataaaatga aatcaactaa attgaaggtt gtattgttat
     2641 cgacagcagc attaataacc cttacagcat gtggtacaac taatagtgct aataataaca
     2701 aagacacaaa gtctagtagt acgatggtta ctaaaaacag cactacatcg gcatcaacaa
     2761 caatgtcttc aatgactgaa aataatgctg aaaagtatca aaaatacgaa gacattaata
     2821 aaggtcaaaa gccggatgaa gtttataaca actttattaa tacagtaaaa aatgatgaaa
     2881 attatgggaa tgatccattg caaaataaaa atctgactat cgttctttac aaacctgatt
     2941 gtccagattg tcaaaaagca gaatcaaaaa tcatgcaaga aataaaagaa ggatttagtt
     3001 atgctccaac attaatgcat gatattacca taaataaacc agcttacgag tattacgcag
     3061 ttgctgtaga tattactgat ggtgtacctg agtgggtaca aaacattcct ggtctggctg
     3121 atgagaacaa tcaatatcat acgccaacag ttgcagtagt aacaccaaag aaagttaacg
     3181 gcacactata ctgggatgta atgggaatga caacaaatac aactgatgaa atgattgaaa
     3241 gtacaactaa atattatatg gatttgggag catataaatt atatcaacaa tcagagcctg
     3301 ttatggacga tcaatccaaa gttaaataga tctttagggc gtaagcccta tttttttaaa
     3361 attaagtgat aacaaataaa tgatttctga aacaaacgtt cttactcaac tactcgaaac
     3421 acacaagcta attaactaga ttataaagga gaatgcgtaa tgaaagaaat cagtgcaaat
     3481 gaagctcata ttccgcaaaa gaatcaggtt ggtatatata aggtgcttca tggtgaagga
     3541 atttataaaa tacagttact taccggttac aataatggtg caaatgggaa gtggttaaag
     3601 gcaacaagta ttcgtgaact tagaagtgaa gtagaaaaaa ttaggcttgg tctcacaagt
     3661 gaagaaatag ctaaactgaa gggaaataat tcttttgtaa ttgaaaaaga aaaggaaaaa
     3721 catctacttt atcgtgagct gaaaattgaa gaatactatg aaattgattt acctgaaaaa
     3781 ttaagaatta ttgatcaacg ttcagaagaa aaatggaaaa ctgaaatata tccaagctta
     3841 aatgactaca agacatcagg aaagcccatg tataactaca caggcttttt aacctacaca
     3901 caatacaaat atgcctttcg caaattaaaa ggcattaaac aagctgaaat tgccctgtat
     3961 gagatgaaaa aagtggatag attgaaattg attcaagatt tagtgcaaaa tacatggaat
     4021 caagcgattg tcgagctaga aaaagaaaat gggaaaattt taactaataa atatctgatc
     4081 gtaaatgaaa ttgaagaatt aattggttta ttttcatgtg aaaaaggtga agtcttcttg
     4141 aagtcatcac caacctattc aattttggac agtccgtatc agtttataca ggcaaggaga
     4201 tgagttagat gtctagcttg aaagatgact atatccaagc aaaacaagag tatgaaaaaa
     4261 tacagatgtt gaaatctgag aaagtcgaat tatttttaac acaaaaatta gcagaggatc
     4321 atattgctaa cttagatgct aaaactttag aggaatatga tcggcagttt aatcagatac
     4381 atcacaatat cattttgctt gttgagcagg caaagcgaag gtttgaaaaa gcggaatatg
     4441 atctattaga tcaaggaatt gtatgcttgg ataagggatt gcgaagatat tatggtgcag
     4501 agttaaaaaa gcaaaatgta gatagaaatg cactaaaaca tgaaatctta gaattgataa
     4561 tgcaacgaat ttgaagggat agaaagcaaa tgtcacaaaa cattagtgct gtaaaacaat
     4621 taatagaaga agatttagag accacagttc agagattagc ggaacgaatc cattttgcaa
     4681 attatcaaac catctctaac tggtcaagca ggaacagaaa tccggaagaa attccaatga
     4741 aattttttta tcgaatcgga aaagaatatg gtgttgatcc gataaaaatt ttcgagaaga
     4801 ccatgattta ttactatcat ggaacaccta acgaagtgtt agaacatctt ttggaagagg
     4861 caaaagaaaa atcatcaata ttagagctat cgcaaaatga caaagttatt caagtgaaat
     4921 gcgttgatcc aacaggaaag attattgtcg gttttgatat tgaaagaaaa tccaaaatag
     4981 attttattac acaattaaaa aagataaata atttagatat tctaacgctt agaccagatc
     5041 atgaacagtt gtttatgagt tttaaaaaac aattgaaaga aatacaaaaa agatataaca
     5101 aggtgtttcc taatgcgtga aaagctcaaa gaaatcagag ttttttggat aattaacaaa
     5161 gaatgtatca tcttatatac tcttggattt cttagcatga tcttgttttg gtggttatat
     5221 ttaaaacagt aattggagag ggtcaagagg atttttatca agataaggat gtggaaactg
     5281 catgtggaat aatagattaa aaacaggatt gttattaata gttatttcct gcgctatgat
     5341 gattggtatg aggatacaaa gggaacaatc ctattttgaa gtttctgcta acaatgtaat
     5401 agaaagatgc cattatggtc aacatttttg gactggggaa gtcagagaaa atatagatcg
     5461 tgaatatgtt caaagaattg tttgggatgc atattctatc aaagattatc ctaaaagttt
     5521 aacgagtaga ttattttaca gtgaaaaaga taatcaaaaa ctctcagatt tgatgatgaa
     5581 aaaagtatga ctattattac gaaagagaaa cagagtgcta tattcgaggg gaaaaagcct
     5641 acaacaaaag tgactattgg ggtgacaagg cgaagcgatt aactgcaaat tttagagtgt
     5701 atgaatcaga gtttataaac ttgacctttc ttaatagtgt ttttattgat tatgtaatta
     5761 ctacgaaacg cattggaagt tattcaagta cctacgcatc cttagttcca atgttaaact
     5821 cgatgagccg tttcttaaaa gaaagagaaa agaaagagct acagtatatc aaagaaatca
     5881 tgccggattt tgaaatgcac gaatggcaaa ttgctttatc agattggaaa ttggcgaata
     5941 aggttcgtag aataacacct tttcaagcca agcgcttttt gagagctatg aaatttgtgc
     6001 aataaaaaaa gccaccagac aagttgatgg agactaacac aattaccaac agttgtaatt
     6061 gtgttagctt acaaattaat tatggtgttt agtcaatccc aaattgtgaa atggcaccaa
     6121 taattggaaa ggaaaaatga aatgtctgaa gatttacgag agctgaagtt acgaaagaag
     6181 cagtatgatc agtatttttc cggtttgttg aataaacata ttgaagaagg acttgatcat
     6241 gattttggaa aagatgaata ttgtttatat tgcgaacgtt acaatgaaaa aatgtctgaa
     6301 tatctacagc tgaaaaaaga gatacagaaa ttagagaaaa aagtacatgc ttggaagtat
     6361 aaagattcca tgtctggtta tgttgaatct caaaataagc caagaaaaaa gaagcaagcg
     6421 tatgttctaa agatggtaaa tggggaagag ttaattgtat tagcgtacag tgaagaagag
     6481 gttcgagaac tcgttgaaac acctgtcagg aaaaaggttg aaacaataaa tgagatagac
     6541 gacagccaat acaatagcat ctatattgaa acaagtcatg gtggatataa gaaattagca
     6601 actttcctta gaagttctaa agttgggata atttctaaaa aagacataag tgctgttacc
     6661 gatagttttt gtactttatc tgttcctaaa gcttatttcc aatacgatag taaaagattt
     6721 gaacgcttag agaaattctg tagaccgtat actgtattga aaactaaaaa atttaataaa
     6781 actaaaagag tttctataca gttaccgact ggtcaaatct cattaggtga aaaagactat
     6841 ctgataaaag taggaaaaga gttaattata aaagtaccgg aacacttatt taaagaaaat
     6901 tttgagatac gtgaaacctt ggtatggaaa gaagaaaaat agtttggaag acatagaatg
     6961 gtataagggg aaattgaaat ggcagtaaat aaaatattgc aggtactaat catagacgaa
     7021 tttggcggag gagaatggtt tgatgtgcag tccatagact ttgaagaaga agtcgtagtt
     7081 atagaaaata tttacggcga agtatattca tattcgcttg aaggtgagaa tattgaggat
     7141 ttacggttga ttggtgagta gaaaaaaaca gaaatatcaa aatggagata aaaattaata
     7201 gcatgtaaag atagtcatgc ttgggttaaa aatgttaaaa ttcaaaaaaa tgagtcagaa
     7261 gggataaaag tatgaaaaga gaggaataca aacaaagatt aaacgaactg cttgaagagg
     7321 acgaaacatt aactcatggt tcgcctgatg aaattctata catgattgat aatatggtga
     7381 tctttggtgg atatgaactt ggtaataggt cagttgatca taatatttta gaatttgatg
     7441 atgtatcatg ggaagaaatt cttgattggg gaattttggc ggtacctgaa actaaaacct
     7501 atattagtga cactatggtt cctttttttg aggaattgga ttataaaaga cttcccaaaa
     7561 atgaaaatca tatactggga ggaaactaac aatgttaagt gacttattta ttttactgat
     7621 ctatctaggt gtaagtgaaa ttattgcgta ttttttgttt gtcattgcta attatggtat
     7681 ttccagtgca atcgttcaaa tgtttagatt accagtaagt gaactaaaaa aatgatgaga
     7741 ttatcagcat atcttttaat gtttttgaat gtggtcacgt taatctttgt agtaatcggt
     7801 gtgactttcg atttaatgga atagtgggaa atctataatg gaaaaaagag acacgaatga
     7861 acatattttt tgaatcaata ttgttgatgg tttttgcgat cagcgcttac cagaaatcta
     7921 aaaaagagta atgattgttt aatcatcact ctttttttgt agggaaattg aaatatgtgg
     7981 agcttgtatt ggtttagtta ggattgcttg gctataagga gctagttctt tatcaaaacc
     8041 atcaaagtag gttttcagta gcgatttaac tgatcgctca tcttgtttga tttggataat
     8101 ttcagcatcc aaatcggttg tgagatcagg agcttttgat gcgattacct gatttttttt
     8161 atcttccaac tctcttaggc tgtttaacaa gttgtaaaaa gaatcatttt gattgttcat
     8221 tccaacgtga gttgcaattt taacagaagt ttcgtccgta ttgtcatcaa aagaactcat
     8281 tggaatatca agtagtaacg aggatgtttc ttttactgac tttttcttta cagcattttt
     8341 tgtttttcca tctttttttc tctttactcg agatgttttt ggagctagtt taggtaaatc
     8401 acttgtttta tcagtcattt attagctttt cctttctatt aatttatgtt attatattat
     8461 cataataaca taaaaaagta cactttttgg gggcgtagtt attgaaaaaa tctaagagaa
     8521 agattgccac gttgcttatg ttaatggtgc aatttacagg gattgcaatg agtgtaatca
     8581 caataaatcc gcaagtgata catgctgatg ggatagctac ttatgatgca caatttaact
     8641 gtactactga aggtagtggg tcaggaacag atagcgatgg aaacgatact ggaagtggcg
     8701 ctgtatcagg tgatgtagca aaaaatattg atgatattta caaatttatg aatggggaat
     8761 atgggctatc aggtgctact atcgcaggta ttctaggtaa ctggaaacaa gaatcaggta
     8821 atgatcctcg aacggtagaa ggttattacg gtgatggaca gagagaagtt gacttcatca
     8881 aacaattcac tgatggtctg atgggtattg gctatggtca atggacagca ggtcgccata
     8941 ctgcattagt aaactgggcg aagaaaaact ttggtggcgc ttggtggacg acagaagcgc
     9001 aattggattt tatgttcaaa ggtgatggtg gatttgttgc tatattaaaa gattatgctt
     9061 taaacgcttc tgatgatgtt gtggcaaatg ccgtagcgtt tcataagaat tgggaaattt
     9121 cagcagattc cgaatcagct gtagtggctg tacgtggtgg aaatgcaaaa gaaatctgga
     9181 agtacatgaa aagcaaaggc atggacggag ctaaagatgt aagcaaaatc aataaaattg
     9241 ccggaggaac aagtaccggt ggtggatcaa ataattcatc aagctcagca tcaggaacag
     9301 tagaagatgc ctgtgcaact acagatgatg ctaattctgg ttctggatca atgggtaaag
     9361 aaggaaaaat taacggtaaa aaaggtcaag taatagcgaa tatgacttat gaagaagctt
     9421 tgaaaaaata tgggaaagcg atcacgctac caaaattcaa agaaccagat tggtcaactt
     9481 caccttttaa cggaatatat caaggtcagt gtacagagtt gacgtgggct tatatgagcc
     9541 aattatacga tgggaatcaa ccgactactg gaaatggtgg ctacgtatgg gaaagctaca
     9601 aatcggcagg agcgaaaata acgaacaaac caatcgtagg ttatgggttt agtgcttcag
     9661 atggatggtt atgggctgtt ggcgatgcag ggcatactgg tgtagttata gcggtgtttg
     9721 aagatgggtc atttctatgt gctaacttta atgttccacc aacccaagct ccaacaaggg
     9781 gagtttcggt aactttgatt gatggagtgg acggatcaga taatgtgcat ttctttagcg
     9841 gtgtaggaaa agctaaattt gaaatcgaaa aataaattgg aatgaaggac gatatagatg
     9901 aatagtaaag tgaaagatac aattatcatt tctttgcttt ctggtatgtt attagcactg
     9961 cttgttggaa tcctattctt caataagcag aatcaggaca tagaagctga aaaacacagt
    10021 gtgcatattg aagataagct gacattcttt aaagaggtta aaccaaatga ggtggatgga
    10081 ttacggaaag atttagaaaa tgatattcaa gaaatgttga atggatcagt tcaaaataag
    10141 tttgcagatc aatcaggtga agaatttttg agaaaactat ttattgtcac aggtaaacca
    10201 ccaattactg ataagagtag tgagaaagaa aaaatcgagt actataagcc ttttactttt
    10261 aagctaacaa actttggaat taagacatct agtagtgggt tgtatgaagc attgaccgat
    10321 tttgaagttc aatacaatgg aaaaaaagtg tatgatacca cattaaccat cacactaaat
    10381 aatgataaga aagtgactgg gggtgctttt tatgcaaaat catgaaatca ctactgctaa
    10441 aaaggcgatt ggaatacttt ccataattgt gatcctttgt tgtgtggtac tatttcaaaa
    10501 gaaaaatgct tatgataata atgtcaaaga attggaagac cttaaaagta aacaaatcga
    10561 agtagtcaag aataaccaga aagtgaaagc tatgcaggaa gcccaataca aagaattggg
    10621 gaatgctgaa atcaaggaac aaagtaggaa attctttaat ttattttaca actggaattc
    10681 atgggaaaaa tatacgaaga atatgaagga aatacaaaaa gaatttcctc agatagtaaa
    10741 gtctagtcct gttgatattt ctggcacgat ggtaggcact ggtaatagtc caatatctag
    10801 ctatactgct gattactata caacaaatca aaaaggtaaa atggttgaat tgattacaca
    10861 gacaagaaat actccaacaa cagcaacaac aacaatttgg cgtggagtaa caagcatagg
    10921 agaaaatcaa ttgttttact tggagaattt agatagctat gtaagagcgg agtaaaataa
    10981 aaaaagagct aacggtacca acgttagctc tttgtgctga cgatgataac aaaacctacc
    11041 gaaaaaggat tgtttcatca caaacacaaa cagaaaagaa ttgataaaaa acccgaacct
    11101 cagaattttt attaatcaat tcatttagat tataataaat tgagctgaac attacaatac
    11161 gtatatgttg taaaacgtaa aaaaagtcaa aagtaaatac tttcttaaaa agtcaaataa
    11221 aactattaaa gacaatatat atggtttatt tgacataaga aaatggtcta gatgataatt
    11281 gtaatataga attgtaggct taaataaagc ataaaatacc ttttatgata aggtatagct
    11341 cttaatttta agcagttttt agatataaga gtgaaagtaa agtgggggag aataataatg
    11401 gcagatcgta aattagaaaa gttattagaa gaaacgtgga atccaaaaga atttagtgaa
    11461 ttttttatgg agaattttga aactgactta gcagtgattg ttaaagatgc tcttagagag
    11521 caagggtatc ctgaaactgc aaactatata aacattaatt ttactttgta tactgaaaat
    11581 aaaggaactt gggatttttg ggctacttta gcaaataagg agttaagtga taaatcagac
    11641 acaggaattc gtaacttttt tgaatcaaac agagatgatt atatgtatgc taaccatcaa
    11701 gataaattga actttagagt agagtttgat gaaacacctg aagaatttat agaaagacaa
    11761 ccgcctaaag aaaatgtagc aaaggtattg gaagatcgtt ggaattcaga tgaaatagtt
    11821 tcaacaatta gcgaactagg cggacaatat gaaccgctag tagaagcggt tagagaagag
    11881 ctaagactga ataagtttcc tgatgttcaa aatattgatg tttctcaaat tgaaataaac
    11941 gtcaagatca cgaataaact tgattatggt agttgggcag atatagcatt agaaaaatac
    12001 atctactcaa cgttaaaaga gtttatcgaa aatagaatgg atatcatgta tctacagcat
    12061 ccacagtatt taaactttgg tgttgaaata gctacacctc ttgaagaatg gaaaatggag
    12121 caagggcttg actagccttt gctccatttt tttaacagta aagaaagtat aaaaagttaa
    12181 ggactaaaaa ggctgcacta ccagtctttt tagccctttt cattttgttt ttgaacaagt
    12241 aaaatattac tatgaaagcg aatattctcg aagcaatctt ttttgacgaa caccataatt
    12301 gggataattt tgttgagaaa cacgggcgaa agattcggct agtcgtcaaa cgggaagtaa
    12361 acaagtttag atattgtgga gatattcgaa aaggataccg actgtttgtc tgcgaaggat
    12421 gtcatcaaac aaagtttgtt cccttgaaat gtcgtggaaa attctgtcca acatgtgcaa
    12481 caggtgaaag ccaaaggtgg tcagcggttg tggcgaatga tatgtttaaa gtgacacatc
    12541 ggcacgtaat ctttacgatc gatgaggggt tacgggaaat ctttatgatg gaaaactatc
    12601 gagattcctt actgaaagga ctaatggatg aagccgcaaa aattattctt gcctattttg
    12661 agaaaagaaa ggtgaaggca ggtgtagtag ctacaatcca cacctttgga tcaaaactag
    12721 aatttaatcc gcatgttcat atggttgtca ctatgggtgg cttaacaaga gatggaagtt
    12781 gggaagacta cgattattta cctttttcta tgttaagaaa atactggaaa aatgctgtat
    12841 tgaaactaat tagacgaacg ttaggtgagt gggacaagca aagagttcaa tcaagattac
    12901 aagctgcgta caagaacaat ggagaagggt tttacgtaaa tgctcctaaa agaagcagga
    12961 caaatctaaa gtcactactc caatacatca gtcgttatat gaagcgtggc ccgatcgcat
    13021 taagccgaat cttaatgtat gatggcgaca ctgtcatgtt caactatatg gacaaacgaa
    13081 cgaatactaa agagacgatg accatgagta tagacgaatt catagctgca ctgattcgcc
    13141 atattcaaaa taagaatttc aaaacgattc gtcgctatgg aatctatagt cgtagaatca
    13201 aaacattaat gaaaaaggtc atgaaggagt atcagaaacg agtaaaaaag ctgtttatca
    13261 atctgaatga ggccttaaga ccaaaatcct gggaagaaag aataaccgaa gaatttggtg
    13321 aaaatccctt agaatgttct tgttgcggtg agtactatga attcgttggg atgagtgtgc
    13381 gcaaaaatgg aaggttagtt attaaatatg cgaaagataa ccatgcaaag cgatttatgc
    13441 gagaggagaa tcgaaaaatt gaccaaaaag aattcaggaa acagtatgaa gaagaaaaag
    13501 aaaaaacttt taaagcaatt cgctgggatt ggggacgcca acgtgaaatt tatatgtcta
    13561 agttgtggtg aaaaagaatc aatcccaatg gatgtagtaa aatttttaga tgatgcagat
    13621 attgcaaatg atccgaacaa tcctccccaa tttacctgtg aaaaatgtgg gaaggagatg
    13681 tatccggaat attatagaaa tgcccttgga atagagttta agatcagtga tcttcaataa
    13741 gaaggttaat catacaaaaa gtccaccgga gaatgaattc tccggtggtt ttcttatgct
    13801 ctaattgcgt caactggtat tagattttca taccaattat tgaaaagtct atttgaatat
    13861 agtatgaaag aaaaatttta ctagcatatt ttatcttacg aaaacttgat aaatcagcat
    13921 tttaagccga tagtaaaatt actaaaagat ttattgttga caaaggtaaa aaaaccacct
    13981 taccattggg ttgtggttat aaccagttta aaagaaggag aagcccatgg aaaattcttt
    14041 taaaaacaaa gctttgtatc atcaacttgt agatttattg aagaagcgga tggaaagcgg
    14101 catgattcct catgataagc tgccatctga gcgggaatta acagctcagt acggagttag
    14161 tcggacgacg gtccgtttag ctttgcaaga gctggaaaac acgggataca tttatcggcg
    14221 tcatggaaaa gggacatttg tctctgatat caaaacagct gctgcagatt tagctggtgc
    14281 ctacagcttt accgaacaaa tgaaaagcct cggcagacat cctgagacgc gaattttatc
    14341 ctttgaaaaa atggaagctg ataaatttat cgcacaacga ctcaatcttc ctttaggaga
    14401 agcagttttc aaattgagtc ggctgcggat cgcggatcga gagcctttaa tgattgaaga
    14461 tagctatctg cctgtcaaat tcttcttgtc attagatgat cagctattaa gaagcaagcc
    14521 cttgtacgat cttttttcag aagattttaa gcaaacggtc cgtttagcag atgaagagct
    14581 ttatgccagc atcgcttcaa aggatgacgc gaaacagctg atgatccctg aaggagcacc
    14641 agtcctgcat ttagtccgtc agacctacaa tatgaaaaat gaaatcattg aatttacttt
    14701 gagcgtcgct cgcgcggatc aatttcatta tcagattcgt catattcgaa atagttagga
    14761 gaattaaagc atgtttacaa tagaaaaaga aaaattggaa caaatgggag cggagatcac
    14821 gacgcgtgag attcgccaac agccggaact ttggaaagaa acgattgacc tttatcagtc
    14881 agcccaaggg gaattagaaa attttcttac agaagtccaa aaacaagcaa agggtcagcg
    14941 tacacgcgta attttcaccg gtgcgggaac ctcccaatat gtaggcgaca cgctggttcc
    15001 ttatttgcgc aaacacggcg atcgtcaagc cttcagcttt gaaagtatcg gaaccactga
    15061 catcgtggcg gagcctgaag aatatttaat caaagaggaa ccgaccttac tggtatcctt
    15121 tgccagaagc ggaaacagtc ctgaaagctt ggcagcagtt gaaatcgcaa atcaagtcgt
    15181 ggatacaatc catcatttat caatcacctg tgcaaaagag ggaaaattgg cgcaaatcag
    15241 ccaagcagac tccaagagct ttttattctt aatgcctgtt cgttcgaatg atgacggttt
    15301 tgccatgact ggcagcttct cctgtatgac actaggcgcg ttgctgacat ttgatcaaac
    15361 agcactagcg gaaaagcaaa actatgtaga aacattgaac gctttaggaa acgaagtgat
    15421 cgcccgtgag catgacatcg aagaaattgt cgcacttgat tttgaacgaa ttgtttatgt
    15481 cggttccggc agtttagcag gcttgaccag agaagcacaa ttaaaaatcc tagaactgac
    15541 cgctggaaaa atcgcgacag tctttgattc atcgatgggc tttagacacg gaccaaaatc
    15601 atttatcaat gaaaaaacta ttatgttcgg ttttgtcaat aatgatccat acacgcggga
    15661 ttacgattta gatatcttag aagaagttca cgaagatgaa atcgcttccg gtgtctttgc
    15721 tatcactcaa cccggaaaac ggaatttctc tggggatacg ttcgagtttg caactgggac
    15781 ttctttactt ccagatgcct atttagcact aggctatgtc atggtagcac aaactgtcgc
    15841 gcttttaaca tcggtgaaag ttgcgaatac acctgacacg ccttcaccaa cgggaacagt
    15901 caatcgagtg gtaaaaggcg taacgattca tgactataaa taggaattaa ctgggaggaa
    15961 gaaacatgct tacattaaca acaggtaaaa aagcggcgat ggaccgttta tcaacaaagg
    16021 atggcattat cagtgcctta gcaattgatc aacgtggggc gttaaaaaaa atgatcaaag
    16081 cgttaaatgt cgaaccaacg gataagcata ttgagcattt taaagaattg gtatcgagcg
    16141 agctgacacc atatgcgtct tcgatcttat tggaccctga atacggtctg cctgcagcaa
    16201 aagtacgtca tgcagatgca ggtctattgc tggcatatga aaaaacaggc tacgatgcaa
    16261 ccacaccagg acgtttacct gatctattag cggattggtc ggttttacga ctaaaagaac
    16321 aaggtgccga tgctatcaag tttttacttt attatgatgt ggatgaagat cctgcgatca
    16381 atcatcaaaa gcatgtcttt gtcgaacggt taggcagtga atgtgcagaa gaagatttgc
    16441 cattttactt agaattggtt tcttatgatg cgcaaatttc agatgctggt tcatttgact
    16501 atgccaaagt gaaaccgcac aaggtcaatg atatgatgaa ggaattctca aaaccgcaat
    16561 acaaagtgga tgttctaaaa gtggaggtcc cagtgaatat gaatttcgtt gaaggctttg
    16621 gtactggtga aatcgcttat acaaaagaag aagcggcaaa ctatttctta gaacaaagcc
    16681 aagcaacgga tttaccattt attttcttaa gcgcaggtgt ttcaacggag ctattccaac
    16741 aaacattggt atttgctaaa gaagctggct ccaccttcaa tggtgtgctc tgtgggcgtg
    16801 ccacctggaa aaatggtgta aagccgttta ttgaatcagg tgaagctgct gctcgtgact
    16861 ggctgcaaag cgaaggtcgt gaaaatatcg aaagcttgaa caacatgtta aaacaaacgg
    16921 caagctcatg gcatgacaaa gttcaagtcg cagaagaaga agcggtgaac taggaggcga
    16981 gctcgtgata gtaacagtaa cgatgaaccc gtccattgat atttcttatc cactggagaa
    17041 actgaagcta gacacggtca atcgaaccga tcaggtgagt aaaacagctg gcggaaaagg
    17101 acttaatgtc acgcgtgtca ttcatgattt gaagggcgat gttttagcaa cgggtgtttt
    17161 aggcggtttt catggcgctt atatctcgga agaattaaag aaagcaggta tcaagcaggc
    17221 atttacagaa atccaagagg aaagtcgaga ttcaattgcg atcttgcatg aaggaaatca
    17281 gacggaaata ttagaagctg gtccgacagt ttcagaagcg gaacagcagg cttttttgga
    17341 aaattttcag gagttggtta aagaagccga gattgtcacc atttcaggca gtctggctaa
    17401 agggctccca ttgaattttt atcaaaggct cgttcaatta gcggaagaac aagtggtaaa
    17461 agtccttgtg gatacctctg gtgaaagcct gaggcaggtg ttaaccggtg agcataaacc
    17521 ctttctgatt aagccaaacc ttgaagagct agaagcttta ttgggtcagc cgttttcaat
    17581 tgatgactta gaagagctgc agtcagcttt agctcagcct ttatttactg gtgttgagtg
    17641 gattgttgtg tcactaggca aagatggggc gcttgcaaaa tatcgtgatt ctttctatcg
    17701 agtaacgatt ccaacgatta aaacagttaa tccagtgggg tcaggtgatg ctactatagc
    17761 tgggtttgcc tatggcttat cacaaaaaat gagcgtaaca gaactgctga agctttgtat
    17821 ggcagccggt atggccaatg ctcaagaagt gcgaacaggt catgtcaatc tagcgaatgt
    17881 ggacatgcat tttgaagaga tcaacgtaag aaaggcttcg cgaactcgct cagcttttga
    17941 gcaataagac caaaatattt ctaaattgcc aagaaacaca gtgatcgaag agaactgatg
    18001 ttgattggta cctacttggt gcttctcaaa tttcgaaata tttttgctta ttgccgaaaa
    18061 agctagttcg tgaagccgga catggatatg cctgctgtaa aacgatttat tcatgtgaaa
    18121 attttatact tttttcatag taaaaaagat cgagcaataa gctcgatcta gtcaggatta
    18181 attgtttttt gagaccagtt caattttgta aaaattccat tttttatagg attcaacata
    18241 ttccagcatt tgctgtgtat cccttcgttt ggtcacacgg acttggagaa cagttggttc
    18301 atcagcagaa atctccagca gctttgctgc atctgaagga gtcgggaact tgatttcatt
    18361 tgtttcggta aagtcttctt cgttcatatg gatattataa tctagcttaa agcgttgata
    18421 gatggaattg taatagctca gttcttgata attaggattc acatattgtt ccggcaaata
    18481 ggtctgttga tagatatacg gagtttcttc ggctttgcgc aagcgtttga tgcagtaata
    18541 aaatgctgta tcaggcaatt cgagcttact taaataaacg ggatcatttc ctcgtgtgat
    18601 tgataagact tgtacttgat cattacttat aggaaacaac tcgatatcgg aaaattcgac
    18661 tatttttcct ttacgggcgc gcgagacgaa agaaccgcgg ccttgatgtc gaacaatgaa
    18721 tccatccttg actaaatcat tcaacgcgcg aatgacggtg attgagctga cactgaacat
    18781 ttctgccaac tcggcttccg tataaaattt gtcgccattt tcgaatttgc cagaaatgat
    18841 ttgctgtttt agttcatctt ttatgatttg gtattttggg atgaccatag gaacctccaa
    18901 acaatgaata ggaattaaaa gtttcattag aattttttga ttttgtggtt atggcttgat
    18961 tttaacacat tccactaaaa taaggagagt tgactttcag tatcgaataa tttaatatat
    19021 taatatatta aaaacgcttt catttaagga gggagctttt gaaaacattt gagattaaag
    19081 aagattttct tttaaacggc gaggccttta agatcatgtc aggagcaata cattattttc
    19141 ggattgaccc agcggattgg tatcactcac tgtataacct gaaagcttta ggcttcaata
    19201 ccgttgaaac gtatatacca tggaatttgc atgaaccaaa aaaaggtgag ttccattttg
    19261 aaggaatact agatttggaa cgctttttat caattgcaaa ggaactcgag ttatatgcga
    19321 tcgtaagacc atcaccatac atttgtgcag aatgggagtt tggtggattc cccgcttggc
    19381 tactaaacga agacacacgc atccgaacaa atgaaatcgg ttatttaaaa catgtggctg
    19441 attattatga tgtcctcata aagaaactgg ttcctcatca gttgtcaaat ggcggaaata
    19501 ttttgatgat ccaaatcgag aatgaatatg gttcatatgg agaagaaaaa gactatttac
    19561 gttcggttcg agatttgatg ataaacagag gaatcacggt tccgtttttc acttcagatg
    19621 ggccttggcg tgcgacactt agagcaggca gcatgataga agaagatatt ttagttacgg
    19681 gcaattttgg ttcaaaggcc gaagagaatt ttgcatccat gcagagtttc ttcgatgaac
    19741 acggaaaaaa gtggcccctg atgtgcatgg aattttggga tggctggttc aatcgctgga
    19801 aggaacctat tgttcaacga gatgccgagg agttggcgga agcagttaag gaagtcttaa
    19861 ttagaggcag tatcaatcta tatatgtttc atgggggaac gaattttggt tttatgaatg
    19921 gctgctccgc acgaggagtc attgatttgc cgcaaattac ttcttatgat tacggggctc
    19981 cgctaaatga gcagggcaat ccaaccgaaa aatatttcgc aattcaaaaa atgattcatg
    20041 atacgtttcc tgagattcaa caaatggaac cgttgacaaa gaacacaatg gaagtaaaag
    20101 gaattcattt aagaaataaa gtcagcttgt tttcaacttt agacacgatc agtcaaccgg
    20161 tgaaaacgac atatccagag acgatggaaa tgctaggaca aaatactggc tacattctgt
    20221 atcgcacatc gattaaaaag gacgcggaag aagaaagact gagagtcatt gatggtcgcg
    20281 atcgtagtca gctatttcta aatcaaaaat tacaagcgac acagtatcag acgcaaatcg
    20341 gcgaggatat cattgttccg atgactgaag aaaccaatca attagacatt ttgattgaaa
    20401 atatggggcg ggttaattac ggacacaaat tatttgctga tacacaaaat aaggggattc
    20461 gaacaggagt tatggctgat ctgcatttcc tcactgattg gtcgcagtat tgcttgccgc
    20521 tggattcttg tgaggcagtt gattattcaa gagaatggca gccagagcag ccaagttttt
    20581 atcgctatga agtagtgctt gatgaagtgg aagacagctt tatcgatctg tcgaattttg
    20641 gaaaaggtgt cgtttttgtc aatcaagtaa atatcggacg attttgggaa gttggcccaa
    20701 cactatcgct ttatattcct aagggattac ttaaagaagg caacaatgaa atcgtgattt
    20761 ttgaaacaga aggaaccttt caaccagaga ttcaattggt aaaaaaacca ttatataaag
    20821 aaatgaaaga gggataacaa tgagtattat tggagtaaga attgacggac gtttaattca
    20881 cggacaggta gcaaacttat ggacaacaaa actgaatatt acgcggatca tggtggtaga
    20941 tgatgaagtg gcacaaaatg atattgaaaa aagcggactg aagctggcta ctccagcagg
    21001 cgtgaagcta agcgtgctgc cgattgaaaa agccgctaac aatatcttag cagggaaata
    21061 tgattctcaa cgtctattga tcattgcccg caaacccgat cgtttattga agctagttga
    21121 gttaggtgtt ccaattgaag aaatcaatgt tggaaatatg tcgcaaacag atgaaacgcg
    21181 ttcaattact aaatcaatca atgttgtcga tcaggatgta gaagtattca accaattaca
    21241 tgctaaaggc gttcgattga tcgcacaaat ggtaccaagt gataaagcag aagacttcat
    21301 gaatctatta gcgaaatagg aggataagta aatggatatc ttatggtggc agatcttatt
    21361 attaacatta tatgcagggt atcaaatttt agatgaatta caaatttatt catcattgag
    21421 tgcaccagtc tttgccggat tatttgccgg cctagtaatg ggcgatttaa aagcaggact
    21481 tattattggc ggtagtatgc aattgaccgt actaggtgtc ggtacatttg gaggcgcatc
    21541 aaaaattgac gctaactccg gaacgattct agcaacagct ttttcagtag cattgggaat
    21601 gaatccagag caagcgatcg ctgcaattgc ggtaccagtt gccagcttga tgattcaatt
    21661 agatattttg gctcgttttg ccaatacgta tttcgctcat cggattgata aattagtcga
    21721 agatatgaat tataaaggca ttgaacgcaa cttcttgatg ggggccattc catggtcatt
    21781 ttctcgcatg attccagtct ttttagcgtt agcatttggc ggaggcttag tcgaaaaggt
    21841 tgttgctgtc ttgaatggtg atttgaaatg gttaggtgac ggtctatctg tagccggagc
    21901 agttttacca gctgtcgggt ttgcgatttt attacgttac ttgcctgtga aaaaacactt
    21961 tccttacttg atcctagggt tcacgttaac agcgttacta ggaacagtct ttacgaatat
    22021 gcaggtttta ggcactggtg ttgcgggtgt tgtgaagaat ttcgaaggca ttttcaattc
    22081 acttcctatg ttagccatcg cattgatcgg atttgcttta gctgcgatca gttataagaa
    22141 tggacagatg attccaagtt ccccagcacc gaaagaagtt gcttccaatg attcagatga
    22201 aggagagatt gaagatgacg aaatctaatt ataagttgac gaaggaagat tttaagcaga
    22261 tcaatcgcag aagcttgttt accttccaat taggctggaa ctatgaacgg atgcaaggat
    22321 caggctatct ttatacaatc ttgccgcaat tacgtaagat ttatggcgat gacacgccgg
    22381 agttaaaaga aattatgaag actcatacac aattttttaa tacgtcaaac ttcttcaata
    22441 caatcgtgac tgggattgac ttggcgattg aagaaaaaga agggatcggc ggaaaagaca
    22501 ctgtatcagg gatgaaggct gggttaatgg gtccctttgc ggcaattggg gattcgatct
    22561 tcgccgcatt gattccaacg atttttgggg ccttggcagc gaatatggcg atcaatggaa
    22621 atccaactgg tatcttcatt tggatcatcg cacaaatcgc ggtaatgatc ttccgttgga
    22681 aacaactgga attcgcttat cgtgaaggaa tctctttagt tacaacgatg cagcatcgct
    22741 taactgcttt gacagacgcg gcgactttgc ttggggtctt catggttggg gcgttagttg
    22801 ccaccatgat caatgtaaaa ttctcttggg caccgagcat tggtgatgtg acgttgaata
    22861 tgcagaacaa tcttgatatg atcttaccgc gcttattacc agcaggaatc gttgcagcga
    22921 tttattggat gctaggtaaa aagaacatga cttcaaccaa ggcgatcttt atcgtattag
    22981 tagtctgtgt ggcattatca gcattaggtg tgatttctaa ataagttagg ctgattccaa
    23041 tgaataatga ggagcgaacc aatgggaaaa caattagttt tagtgagtca tggactcttt
    23101 tgtgaggaat tgaaaaagag tacggaaatg attatgggac cgcaagaaag catccataca
    23161 gtcagtttac ttcccgcaga gtcagcggaa gattttcgcg caaaatttga agcagttatt
    23221 gcggatttag atgattttgt cgtgctggct gatttaatgg gcgggacacc ttgtaatgta
    23281 gtctcgcgga tgattttaga agggcaagcg atcgaactat acgcaggaat gaatatgccg
    23341 atggtgattg atttcatcaa tagtgaattg atcggtacag agcttgcatt agtcgaatct
    23401 gcgacaagta atatttgcca cgtgaatgaa cggatcatcg gtgacgatga tgacgaggac
    23461 gagtaaaatc tcatagaaga tgatatagag gcgtcgttta tttgtgaata ggagctagtt
    23521 tgaaagtcta aaagactttc gaaccagctc ctttttctgt tctgctatta tggtatgatt
    23581 gaggagaaaa gaaagaatgg gagattagag tggatttcaa cgagaaacta aagcaattac
    23641 gtcaaaataa gcaatggacg caggaagaat tagcagagag actatttatc tcacgaacag
    23701 cagtttccaa atgggagtca ggtcgcgggt ttcccagtat tgattcctta aaagctattt
    23761 cgcaggtttt tgatatttct attgatgagt tgctatccaa tagtgaattg ctgtcaattg
    23821 cagaaaatga gcagcaacag cagcggaaaa actttcaaca tttgctttta ggtatttcag
    23881 attgcatggt cggcttatta attgttctgc cgatttttgg tcaagcacaa gggaaccata
    23941 ttgcgtttgt ctctttatgg caactttcgc aggaaacaat tatcttcaag cttattattt
    24001 tttcattcgt tattttaaca atgctgttcg gcatttttga actcgctttt tctaggcgag
    24061 aacaacgaat tattggatcg gtttctttga ttttatcgtt gttcggcgta ctgcttttca
    24121 tcatgactag acatccatac ccggcaacgt atgtattaat gcttttggca gtgaagggga
    24181 tttccctatt aaatagccgt tgatacgcat cgtcacatca aggtgacggt gcgcttcttt
    24241 ttgtttctgg cagtctctga tacgttttat ttggatagct tccaaataat tgttaggaga
    24301 ggattagtca aatgaaaata gcaaagaagc aattagaaac agccatagga ttattgatcg
    24361 tctttatttt atacacgatt tctttatcct tgttcgatgt acagaaaata ggtccgcagc
    24421 attcggaggt gggcttttct acaattaatc aatacgtatt tcagaagata ggtactagtg
    24481 aattttggta tcaagtgacg gaaatcttag ggatttttcc attgataatc gtggggtatt
    24541 ttgctttacg aggatttttc caattgtata cccgcaagaa gctcttacta gtggacaagg
    24601 aaattcttgc gctaggattt ctttatgctg gagtcgccgc ttgctatgtt ctttttgaaa
    24661 aagtcatcat caattatcga ccgattttag tggatggaca gctagaggca tcctatccgt
    24721 caagtcatac ttttctggca attacagtct tactgtcagc tttttatgta ttaagaaagg
    24781 aaacaggaac gggaaaagca atcatcgcct atgtgagcct ggtggtcatg attgcgctgg
    24841 ttatcggacg ttttttgtct ggagcccatt ggggaaccga tatttttggt ggaattttat
    24901 taggtctgac acttgccagc tgctaccttg caggaattga aagtagttct aaacaaaaaa
    24961 aagaacgttg aaaactcaac gttcttagaa gagccacctg tcgggcttga accgacgacc
    25021 tcttccttac catggaaacg ctctaccagc tgagctaagg cggcatagtt atttaacaca
    25081 agatatagaa tagcgaaaac aagcttattt gtcaactggt taaacagaaa aaaatgcggc
    25141 attagctgct gtgaattctt tatttataaa cgagtcgtcg cttacgagcc tgcgacgact
    25201 tgtttatata gtttagagac gatatcatta tatccctttg gttgagtcca gacatttgag
    25261 agcagaataa tgccattttg accatctttt gaaaaatcaa caagggcttc aaaacgtgcc
    25321 ttaactcctc gtgaatggta gttatttgtc atgttataga ttccgctggc gtatttttca
    25381 cctggatacg attgccataa tgcagcacgt tcttgtgttg ttaaaaattt gtcctgataa
    25441 agatcttgaa aatagctgta caaatcctcc cccgacataa acacattgcc tgttcctaat
    25501 tcatctgcgt aagaagatac ggtcgtagga gcgtaaacag ggccggagga actttctgag
    25561 tatgaaagag cctgctgatt gttcgtttct gaatagaagc ttgtttcttt cagcttcatt
    25621 ggttttctta aaagtttatc aaatagtgtg ctgtagtcgg tatgatagac ttgctccaaa
    25681 attccagcta acaaaacata attgaccggt tgataggagt aactagaatt cgcagccaca
    25741 gtcgtttgac gaattgtctc tgaaagtatt ttttgtggat cagtagtgtt caaggcggca
    25801 attttctttt cgtcgatacg taacccagaa ctcatattca gcatatcttt gatagagatt
    25861 ttctcactat tagaaatttg cggataaaag gtgctgagct tttcctctag ggaaatttta
    25921 ccagatttaa ccgcctgcat gatcaaatag gcagtttgtc ccttttgaac ggagccgatg
    25981 caatattgtg tatgaatcgt attgtggatt cttctagctt gatctttcca gccataagct
    26041 ttattcaaaa tcacctgtcc atgctgaaaa actaaaacag taccgctaaa atttttttct
    26101 accaataact gctcaatacc agcggacgta gcattttttg gttcgattgg ttgctgattg
    26161 gtcaaatcag tagttgtttt cgttgcaggt gtgctgcttt ttttcgttgc gtgatgctca
    26221 ggatagctgt gttcagcata cattccgctg aatgctagga gtattaaaaa aagcggaaaa
    26281 acaagtgtta atttattttt ctttcttttt tggtgcttgt gttttgacat aataaatcct
    26341 ctaattctat ttgaaatcgt tccattttta tttcgataaa aattttcagc agttccatct
    26401 aatttttgaa aattaggatt gcatcatgaa ataaaaattg atattatagt aaagtattct
    26461 tccggcatag ctcagttggt agtagcgcat gactgttaat catgatgtcg taggttcgag
    26521 tcctactgcc ggagttttag agatgatctt ttgatcgtct ctattttttt attttacaaa
    26581 tgaatacagt tcgtcgtttt taccaagaat gattgtttgc ccaactttga gattgtcagg
    26641 tgatccttca gcggtttgta aggagaacgt tccgttgaac ttatcggata ccgttatagg
    26701 tagctttaat tctgatcctt cctcatcttt gagaattgct gtttttcgtt catcaaaata
    26761 aacagtcttt attaaataat ttttcgtagt gatctcagca gatttgtctt tttttgtagt
    26821 agtaacagtt tctttagaat tagaggtatt ttctacgact attccatctt tggcatttga
    26881 gcttgtgttt atttgattga atattttcag cgacaagata ccgctaagaa tagtcaatat
    26941 agaaacaagt gtaattaata ctgataattt cctttttttg ttcatttttt cttaacttcc
    27001 tttttgtttt gattagttag atattcctta tctaacaagc ctttttaggc tattaaatga
    27061 ggataaaccc caaaaaaata ttgcaattat gacagtgcaa tggtactatt attatacaat
    27121 aaattttgcg aaaggggtag gtctaaatcg caaacaaaaa gaaattgaac ctagacaaat
    27181 acaacttgta caccgcaagg gaagcaagtt tgattttggg taaaggtaga aattatgtta
    27241 caaacataat caactattat ccaaatcgtt tgcctaaagg ttcgttcaag aaagtgggtg
    27301 acaaaaccta tattataacg gaagaaggaa tagaagcatt gcgatcacaa acagaaaata
    27361 aaaacaaaaa gaaggaatga atatgaagaa aaattcgctt ggtatggttt tatttgcatc
    27421 agctgtactt gcggggttat cagtaccagt aacctcacat gctgatgaat ggactgcaaa
    27481 cacaccggat caaatccaaa ttacaacagg acaatcaagt tatgcgttca aaaaaggaga
    27541 tactatttgg tcaactgtag agaagcttaa aagcttaggt tacaagacta ctgttgctga
    27601 gtttgccgaa ttgaacaatg ttgatttggc aaaaggagaa caacggacta tcccaattgg
    27661 acgaactttc aacatcagta aagatacatt aacagttaag gaagcagatg gcgaagtagt
    27721 tagtcaaact gttcaaaaag ataaacctga tcctgttgaa aatacggagc aagagaacaa
    27781 aaaatccgag actgcaaaag aatcggaacc aacagcaaac acttctgata agacagaaac
    27841 aagtgcttca agtgttgatg gagcaagttc atctaataca aataattcta caagtgagaa
    27901 agaagcatca cagggaacaa gtgaaagtag cactacggaa actgatactg gaacatcaac
    27961 aaataactca caatcaacat caaatgatgc aaatgaatca accagtacat cttctagtga
    28021 tcaatcacaa acaggttcga gtgatgaaac tgacagttct acttcaccaa gtaaacccga
    28081 acaaccaact aatgttgtgc taggcgttcc atttattagt caaggtaaca caatgctttg
    28141 cgaaggaaca tctttgctag aagcgttaca ttataaaggt gttgcaacaa atcaagattt
    28201 aatgactttt gttaaatcaa tgccactatc tcctgataat aatccaaata atggtttttc
    28261 tggtgaatgg agacacaatg tggatggaac ttatcaaggt atgaatccgg ctcctgtagt
    28321 ttcatggggt gttgctaatg gcggaaatgt tgtagatatt tctggttcat cggtacaagg
    28381 attaaaagat gagattgtaa atggaaatcc tgtagtagcg tgggtaactt atgcctttga
    28441 acctgctcaa cataaatcaa tgttttgggg cgatgctatt tggaatcgac atgtagtagc
    28501 cgttgatgga tttaaagacg gtttttacca tgttgtcgat cctgtgtttg gggcaagttg
    28561 gattaatgca ggatcatttg aaacagcata taacgtatct caattagcgg tttcggtacg
    28621 ttaataaaag agattgttta tatactaagt agttaagtat agtctttatt tgtccttgct
    28681 taactactta gaaaacttgt tgctcatggt gggtagaact aaaaggggtg atgctatgaa
    28741 tactagagcg ttgaaacagc ttgctttcaa cgaaaaaagt gattaatagg tgtggtgatt
    28801 ttaacttagg aatgggcgcg aaggtcatta ccacaccgac atatcgtggc tcattttctt
    28861 cgcctaactg gtataaagaa ggagtaacga gagatgaagc atgaaaaaac gataatttta
    28921 aaatcaaaaa taatttattg ttttgcgact ttagtaatgg tgttatctac gcttataatg
    28981 cctttttcag caataagagc tgaagcagat gtcacaaaac cgacaagtgc aaaatttaca
    29041 gaaactggcg taaaaacaga cggttatatt agggttaata tgccgaatca tccaaatgaa
    29101 tggatgattt caagtcaatt taaagattct catggaaata ttggatattg tatggattca
    29161 gaattgccat ccccaacagg aagtggagcc ggaagcttga agtacaaggg agctggcagt
    29221 gatgagttct atcgtatgtt taaaggtggt tttccatcaa aaacagcaaa ggaactgggt
    29281 gcaggaaatg atacagaagc atggtatgca acacaattag tttcatgggt tttagccgga
    29341 aactttaaag tttcacagat tgtatggtca catccaaacc ataccgccgc agaaacagct
    29401 cgtgtaaaaa aagcatttga aaaaatttat gactatgcta agaatggaaa agatacgccc
    29461 aacactgagt tttctatcac agcttctaag acagctgacg aaggaaaata tcacactttc
    29521 acatataaaa cagcatcaaa taagactggt aatgcgaagc tcacttttac atcagcaaaa
    29581 ccagctggta tgaagattta tgatgcagat ggtaaagaaa ttactaacaa cactgtgaaa
    29641 ttaaattcaa gttttactat taaagtacct gtgactacac caagtggtac tttgtcattt
    29701 aaaggtactg ctaatgttag cacaaccaat ccttttactt ttgatggacg aggcgtgtat
    29761 caagatgccg tagttatgat cactacttca gaaacaaagg actctaaatc tttgagtgct
    29821 aaatggacaa gagctgttgg tcaggtaaca gttaagaaag ttgatcaaga tggaaatgct
    29881 ttaaaaggag cggagttcac tctaactgac aataacaatg ctaaatctgt taagacaacc
    29941 ggagatgatg ggttagctac gtttgatttg caacaaggct taacatacag cttagaagaa
    30001 acaaaagttc ctgaaggtta tcaaggttca tttaaaaagg atggtattac tgttaatacc
    30061 gatggacaaa aatttagtta cactgctacg aacacaatta aaaaaggtaa agtaaaagtt
    30121 aaaaaggttg accaagatgg aaaaccatta gctaatgctg aatttacctt gacggatgat
    30181 tcatcccaaa cacaagcaga aaaaacagat gaaaacggac ttgcaagctt cgatattgta
    30241 gcaaacaaga cctacagcct tgaagagacc ggagtaccaa ctggttatac aggcgcattc
    30301 aagcaagaag gaattaccgt taaagatgat ggacaaactt ttgaatatac agctacaaac
    30361 actttgaaaa aaggtgtagt aaaagttcat aaagtcgatc aagatggaaa acctttggca
    30421 aatgcagagt tcactttaac cgatgaaaaa ggtgcaacac aagtagaaaa aacagatgaa
    30481 aatggacttg caagcttcaa tattgtagca aacaagacgt atagtctaga agaaaccgga
    30541 gtaccagtag gttacacagg tgcatttaag caagagggta tcagtgttaa agacgatggg
    30601 caaacttttg aatatacagc tacaaacact ttgaaaaaag gtgtagtaaa agttcataaa
    30661 gtcgatcaag atggaaaacc tttagcagat gcagaattca ccttaacgga tgaaaaaggt
    30721 gtaaaagaag ttaaaaagac ggatgcaact ggtctggcta cgttcaacat tattgcgaac
    30781 aaaacttaca acttagaaga aacaaaagta ccaacaggtt acacaggcgc attcaaacaa
    30841 gaaggaatta ccgtcaaaga tgatggacaa gtctttgaat atacagctaa aaacactttg
    30901 aaaaaaggtg tgatcaaagt tcataaagtc gatgatcaag ggaaagcatt agcaaacgca
    30961 gaattcactt tgacggacga caaaggtgta aaagttgtac aaaaaacgga cagaaatggc
    31021 ttggcaacat ttaatattgt tgccaacaaa acgtacaaaa tcgaagaaac acaaaaccct
    31081 aatggttata cagggaaatg gtctaaagaa ggcatcaccg ttgctgacga tggacaaacc
    31141 tttgaatata cagtaattaa tcaccttgta cctgaaacag taagaacagg cggaatcggt
    31201 acatcagcct tccttcttgt atttctaatt gcaggattga gtatggtgct actgtattat
    31261 cgagaacagc acaaagcaaa ataaaaaagt gttaatggaa aagaagtaaa tatgaaaaaa
    31321 gaaggctgac gtatgaaatc aaaaaaaatt ttttcaaatt taatgctatt tggtactttg
    31381 ctaggagtgg gattgggcgc aagctcaatc tcttctagcc ttggactagg ggggcaagta
    31441 gcatatgcac aacaaaacta taattatcaa ggaactggaa cgattcatat ccataaagta
    31501 acaaatacta atggggatgg gaaccctgtc tcagatattg ataacaaagg gaaagaaata
    31561 gctttaccaa atggtgtaaa acctcttgaa ggcgttgagt tctcttatgt gaaacttact
    31621 aaagatgaag ctaaatcctt gggatggacg gatagtgata ctacaaaagg tcaacatatt
    31681 gatgatgcta aagcacgatt attactaaac aaaaaataca gtgaagtaag tagaatgaag
    31741 actgattcac aagggaatat agacatacct atacaagtaa atacagacga tttaacagat
    31801 aacttgtatt tgattgttga aacaggaaca gtcaaaggtg tagttgaaga agcgtatcct
    31861 atgattgtta acgtacctga actaaacgga tcagatgatc aatactttaa ttatgatgta
    31921 catgtctatc ctaaaaacta tttccaatta aactcagcag agcttgataa aaaagacgaa
    31981 gatggaaagg ctcttgccgg aactgttttt gaattgcgaa aagatgatgg atctgatcag
    32041 gttgttggaa cttataaaac agacagcaca ggtaaattaa ctgtagatgg tttggaatta
    32101 ggtgactatt atttcctaga aaccgatttg ggaacagatg ctaataaaac aacctattta
    32161 ctagatggta aaaaattcaa atttagcgtt aaacgtgggg agactgctaa agtagttctt
    32221 gatgttacca actacaaacg acctgtaatt actaaggtaa ttgataaaga aaccgttgat
    32281 actggcgaag atgttcaata tacattgaaa ccatcaattc ctggtaatat tggtaattac
    32341 gaaaaatatg ttgtcaaaga tgttctaggt gcagagttaa cttatgattc atcagaagtg
    32401 atcgaaggaa tgactttaga tactgattac agtatcgaac gtgacggaca aacgacaaac
    32461 tatgtcttta ctgaatcagg tatggataag cttcagaaac aatttgatgc aggggatcgc
    32521 ttctttacaa ttttgatgaa cgctcatact aatagtaaag ctaaaatgga tacaccactt
    32581 aagaatgatg tttcaacgat ctacaacaat ggatatgaac ccgaagacga aacaccagtt
    32641 gatcacgctt atacaatcat tggtgatcac caattcatta aaacagatgg agatacaagc
    32701 aaagcattga gtggagcaaa atttgtagtg aagaacaaaa ttgatccgaa taaagttact
    32761 tacctaaaac aagatccaac aacgaaatct gttacttgga ttgcagataa atctaaagct
    32821 actgaattcg tttccggatc agatggtaag ttccaaattg aaggcttgca atatacctat
    32881 gatgtagatt ttgataaaca aggtaatcca acaatcacag ataaaaaaat caatgattat
    32941 gctcttgaag aagttgttgc tccttcagga tatacaccaa ctagaaatga tgttccattt
    33001 gtggtatcga atgatgatgc ttctagcgaa gtaacagaca tcaagaacct taaaacacct
    33061 gaaacagttc gtacaggtgg aattggaaca gtagtatttc tagtggttgc aggtgtggca
    33121 ggaacagggc tatatgttgt ctacaaacga gaacaacaca aagcttaatg aaataaaatt
    33181 ccctagagtg tttttggctc tagggtttct ttttaaaaag tgtgtgaaaa gtaggtatga
    33241 gcatgaaaaa gaagaatatc aagttgatca tcttaaaaat tgggatgttg ctatgtttag
    33301 gagtaggtct atatcctgta attactcagg cttataccta ctaccaaact caacaaacac
    33361 taaactccta taaggaaaaa tatgatgaag cttctgaaaa ggagaatgaa gaagtcttca
    33421 aaagatattc agaagttaat aggaaacgaa aagacacaga acaaacctca gtcacgattc
    33481 ctgaagataa taacaatatt ccgtcaaatg gaaatcttca gaaggataaa ttaggtgaat
    33541 tagtgggtga aattcttata ccaaagatta atgtggattt gccaatttat gatggtgtaa
    33601 acgatttcca actatcagca ggagcaggaa tattaaccgg aactgattat ccaactggtg
    33661 ggattggaaa ccattctgtt atatcagctc attcaggcat tcctaataaa aaatatttta
    33721 cagatttaga gttgctcaaa cttggtgata aattttttat tgatatttca gggaaaaaac
    33781 ttgcttatca agtagatcgg ataaaaacaa ttctaccaac cgaatttgag gatttgcttc
    33841 ctgtggcagg aaaagattat gtaacactta tgacatgtac acctgttgga gataattctc
    33901 ataggttact cgttagaggg gttagcatac cttaccaaaa aagtattgtt gagaaagaaa
    33961 agaagaaaga agatttaaag gtaaaggcgc agatgaactg gtatcctatc gtagttgtag
    34021 gggttttatt aataatagct gtgatagtca ttattaaaaa aatagtagca aagagacgag
    34081 gaatgaaaaa tgaagaataa aatactactt tttttgactc ttatttgcac tttggtttta
    34141 acaatttatc ctgcaaatca gctctatcat caattcaaaa caaaagagaa tgtggcggaa
    34201 atccaagaga aaattgagaa aaaacaaact ccttcaaaag aggaagtggc aaaaaaagtc
    34261 gaacaaataa aatcgaacag cggtaaccaa ggattagaca atactcagaa aacagataaa
    34321 ggagtagaca atactcagga aacagacggt ggatcatttg atattcgtga agctgaagga
    34381 aaggtcaatc catacacagg agatgttttt tcaaaaaatc aaacgaaaga ttttgaacca
    34441 tctacctatt caggagcggt tggttatgtc tatattccaa aaataaatgt gctagagctt
    34501 ttgtttctag gcgcttcaca ggagcattta tatagaggtg tggcacaaat gagtgctact
    34561 agtctacctt tatcaggtaa aggtcatcaa acagtaatag caggtcatcg tggcggttat
    34621 acgtcaccac aatttcttta tgttgatcaa ttagtagccg gagaccacat ttatatagat
    34681 tatcttggtg aaaaagcagt ttatacggtt ttccgaacag acgttattag aaattacggt
    34741 cagaattcaa cactgactga tattcctgat ttagatatgt taacacttta tacttgtcat
    34801 ccatatcctc agaactacga tcgtttatta gttagaagtc taagagatga aaaagcaaaa
    34861 tacatcacgc cacaagtaac agttggcaat accgcatacg ctgatgccat tgatagcgag
    34921 tccgtttcag ataagacaga aactgttaca tcttctaatg atttatttga agatgttgat
    34981 cgtgccaaca aggaattaga tggaaataat gatcttaata ttccggaaca aggtagcgta
    35041 gagatgcaag acagaacgtt tgctgaaaag gcaagttcaa tatttacagg aattaccaat
    35101 aaacatcaga aaatgctttt agtcatttgg actgtaatag gagcattagc aagtctaaag
    35161 gttcttattc ttttaatcaa agagtttcga aaagcataat gaagattata aaaattgata
    35221 gagtacagta aaaagggatt gatactatta ttgatctctt ttttattttg aatagagcta
    35281 gattcacttt taaataaaat caaaactgat cttaattcta aagaaaaagt caagaaaaaa
    35341 atacaataaa tttttttatc agaatattta tcagaatatt attagaaaag ataaactcaa
    35401 aagcttaatt taatagggtt attggttgta tttagaaata atgtatggaa aagctataaa
    35461 gcaatagata agatgtagaa aatcttattt gtgaatgaaa aacaagtcat cgtaaaatat
    35521 taataggagg tgtagtaatg gtgggagtat caaaaacagc tttagactca ttagctaaac
    35581 tatttagtag caggtttgat ggtgcagaat ttgttgaata tctaagccaa aacgaaagtg
    35641 gaaaaactct gatcgaaaca atgaaaaaag actatttgaa tgaaaatgac tttccgacat
    35701 ggacgaatat tgaagatgct acatgggatg tagtatgtac gatatattct ccttgggtaa
    35761 cgattgctga ttttgtttta gataaaattg gaggggatac ataccctgat gccaaatctc
    35821 ttgctacaag tgactttaaa acgttctatg gttatctaat aggtctaata ggcaatggaa
    35881 tagatttgaa agttacgcca aaacaaacac ctgaagaaat tgaaaaagaa aaaggagagg
    35941 ttcaaatggc ttatgcaaat gacagagaaa aagtaaaatt attggaaggt aaattatctg
    36001 aagaagaact tggaaaaatg gtgcaagaaa tcaatgaaga cagcaactat tttcctgaat
    36061 tgaaggtata tcaaaatgac gaagatttct ttaatgaaat gtttagtaat agtccatggg
    36121 aagcagtaag taaaacaaat ttaggagaat ggaactttca agatgatcta gttgcattta
    36181 gcaatgatgg gtatttacga tcatattcag aaagtgagta tagagctgaa ttaaaaacgt
    36241 atgaaacgga tattctgatg agctatttaa atctattaga gagtggtcag ggagagttaa
    36301 gagataaagt tgaagaacta ttaaaagaag agctataggg attatttcaa cataaacaca
    36361 agcagaaaac taccaaacaa aacgtaccat gcaaaaagtc ggttaaaccg gctttttgct
    36421 ctattatgag aggagatcaa accatgagtg caacaaccga tatggcttta gaagcagtaa
    36481 taaaagataa tacaggaaat gtcgaaaatg tagaagactt tagcgatatt gcaatcaatc
    36541 tttcagcatg gatttcagct gtaggagaag aaaatatcga atttgagatc aagaatatgg
    36601 atgacttaaa agcaaaattt ccttttattg catcgaaact aagtcaagtt gccgaggata
    36661 aatcgtggaa tgaattagtt agtttttccg aaaaaattta tgatattacg caagaagatg
    36721 agtgtgtttc atgggaaatg aataatcaat acaagaaaat tgacgctttc gtcaaatcac
    36781 gtatagaagg aacagctttt gagtttgaag gtatagatac cgcagataat tggttaaata
    36841 aagaatcctt tattaaaagt atagcggatg atcttgaaaa acaatggtct aaggaagact
    36901 atgcagagta cctaaaaaca gaaagagata cagaagtgaa agaaaaactc actgaggtat
    36961 gtttggatga acatattgat cccaatatcg taaaacaaga agactatgaa gtggttattg
    37021 ataaagttcc tactgatttt gaggaagttg taaagtatat agttgaagaa gcattatcgc
    37081 aatactcttc agatgaggaa gtggacgaag aaactgttcg taccagagtt tggcaactgg
    37141 tttttgatga caaagattat aaatatttga gtgatcaaaa ctcggttaat tggagtgtac
    37201 gattattaat tgatcaaaat gatattgaat agagctgaaa agctctattc agattgtaga
    37261 caaaaaggag ttggtaatta agccactcct ttttgttagt ctttgcataa ttttgaaata
    37321 aaaagccata ggcttttttg ttttccatag ccatgtggct agttttttta aattcatggc
    37381 agcaaacgta agcatcgtgt gcgtggcgac tttttcaaga cctcgatatt tcgtccaacg
    37441 cataccatgc ttttcttttg catctgcaaa tattcgttca atggtttgtt ttctcttttt
    37501 gtaaatttct ctattcaacg ccgtatggcg ttggtgttca agttcatcca taagatcagc
    37561 ccaaatatgt cgagtcacta ttttttgatg ttttgtactc aaagtacaat tttcaagtaa
    37621 tggacaactc acacagaatt ttggatttga tttataggtt cgataaccat cacgagtgat
    37681 agttgaaaat aacaacggtt gattattggg acataaatag cagtcaaaat aggcatcata
    37741 aacaaagtct tttttacgaa acattccttt cactccatga ggtgcagtat atggaagaat
    37801 cgggtagagt ttcaagtgtg acagaaaatg aacaaattta ggcgtcttat atcctgcatc
    37861 agcaaccaca cgctttatat ttggaaaagc tcttttcgac tgtttaacca gatcgattgc
    37921 gacttggctg tcatgcacat ttcctggtgt gattaatgta gataagataa aaccgttatc
    37981 ttcacaggaa gtatgtgcag aataagcaaa ttgtttttct cgttcacctt taacatagta
    38041 accactttct ggatctgaat gacttatttt ttgaagactc aactcacttt ctgtgtccca
    38101 tgtaaaagga cgttttccta cagcaatacg ttctttattt atttcatctt ctaattcatc
    38161 ttgataagct tttgcttgac cgtaggtcat ctctttcgtg aacttatgtt tattggcatt
    38221 tgctttgata tgagtagaat caatataaag gttgtcttcc gtaacgaagc cagcttttac
    38281 agcttgttct agaatatgag agaaaatatc ttcaaataaa gttgtttctc taaatcttcg
    38341 aacatagttt ttaccaaaag tagagaagtg tgggatagga tcctcgaatg aataacctaa
    38401 aaaccaacgg taagcaacat ttgtttcaac gtctttaatt gtctgtctca tcgaacggat
    38461 accaaataaa tattggataa atactaattt aattaagacc actggatcaa tactgggacg
    38521 accataggtt gaatacgtag attctacaat gggataaatg aaatcaaact gaatcgcagc
    38581 atcaattttt cgaactaagt gatctttagg tacaagatca tcaattgtta acatagcaaa
    38641 ttgatttcta ccttcaatcg attgttttct catcattaga atcactccca gaatagttta
    38701 tacaattagt ataaaacaaa aaactgcaaa caacactcca aatttaggag tttgtctaca
    38761 gtctgaatag agctgaaaag ctctattttt tttgataaaa aaactagcta ttttattaaa
    38821 aataatttgg ttcaaaattt atttttttaa cttgataatt ttttgccatc cttttttaaa
    38881 ttggctatat atcaaggttt atagtgggaa taaataaaaa tacatttgac aaaatttaca
    38941 atatagttta ttatatattt atcttattat gataacacaa taaaaggaat ggtggtatga
    39001 aaaagaagaa gtttagccga tcgttgttag gaattttggt tttagttgcg gttggtctta
    39061 gtggcaaggg ttactttcag aataacagta ctcaggaaca tgattttcag atcaaaagta
    39121 gtgttcaggt aggtaataaa gcagacagtg aatcaaaaga atttttaggg atacgttatg
    39181 atccaaacaa atatccaaat aatatcgtaa acattaatga tgggaaatat acactgacaa
    39241 aagaagacca tgaagcatta tcagaaaaag gcagtcaaac cttttgggta aattatgcag
    39301 atttagatca acttggaaga gcaggagatg ttgaagcgtt gatcacctat gatgctgtaa
    39361 attctcactc atctaaaaat gtggaacgtc catctttcaa aagttctgtc catattgcag
    39421 gagaatacaa ggatggagta tttgatcaag agagagatac ttgggtcggc aaagattcaa
    39481 acaatgaaat cactcagcta gaaggctata aaggttatct ctataacaaa agtcattcat
    39541 tagcatggtc gctaggagga gatatggagg tacacaattt aacacttgga acgagagcgc
    39601 aaaatgttgg gaaaaatgat cagaatggag ggatggctta ctcagaaacg attgtacgtg
    39661 atgcaatcta taaaaataag aatgaaaaag tattgtataa agttgatcca atttataaag
    39721 ggaatgaatt agttcctcgt ggttctcatg tcgaagcttt ctcagttaac gataatggaa
    39781 aaacggtaaa ccttaatgtt tatgtattta acaatcaaaa aggaatcaac atcaactatc
    39841 aaaatggtac ttgggtaaga gattagaaat tgagaaggtg aagaattgga aacaataagc
    39901 atcaatggat tagataaatc agttgcaaat cgaataaaaa aaggaaatgg ctactatctt
    39961 ctgaagaagg gtaaatattc agttgctaga gagttagaaa caatgagtat cgtgtatgta
    40021 gctaagaatc attttgacgt agaacaggct atttttgatc cagattctga aatagggaaa
    40081 tgtgttgaat tatcagagaa aactgttagt acaaaagggg cgatgatcat tgagagagaa
    40141 atgttagacg aaatcagagt aatcattcct aaagatacgc agatgtgtga ggacagcata
    40201 agtgacgatg aaccaaaatc agaaagaaaa taaggagata ttcagatgag cgaaaaatcc
    40261 attgaattaa aggaatataa gcgaagcgat ggagaaaaat attatcctgt agccagtttt
    40321 tctaaatcag tatatctggt tggacgtgca ttggtagttg gtgcaattgg catatatatt
    40381 ttgcattggg taacaaaggt tgtacaactg cttgtagata ccttagtaag tattcttgtc
    40441 tcgttaaatg atgttaacgg aacagatgat ttaggattaa aagagatgtt taaagagtta
    40501 ctcaatgcgt tttttcccaa ttatttaagt tattcatata atgtacaaag cttttttgca
    40561 aagctacact tggtagacat ctctatttta gtattagaag caggaacggt attctttgtt
    40621 ggatatttgg ttactttgat gttcaggcat cactatggag aacaaagacc attttttgat
    40681 gatatggaaa gtagaaggtt gaaaagagaa gctctagaag ctatggatgt gaagtatgat
    40741 ccaaacaaga ttataggaga tgaaacgaac aacaaaaaaa gaaaacgaaa caaaacgcaa
    40801 ttagaatccg atgtgctatc aacgcttaaa aatatcaaaa tttctgttca tacaagacgt
    40861 gatctaagtg tcaatgaaga tattcgagaa tatatcgtaa aaatcccgca accaaaaggg
    40921 aagaaagtta gagaaacagt tttacgacaa attcaagatt tagggtcgat cctgacaaga
    40981 gcaacaagcg gacgagccaa atttggtgaa aaagaagatg aagtttcagg cgattatttc
    41041 attttccgag catcagtaaa tattgaaaga gaacgtaagg aaagagtaag taccaaaaac
    41101 aaagaaacgg aaagagcaac atcttcaatc gcagtttcaa attcacaatt ttcttttcca
    41161 atcaatctct ttgccgataa ttccaaaaat atccaaaacc aaaccgaaaa agctagaaaa
    41221 tatgccgaaa ctcaaaagca atctttagaa ctttatctat cttctgctga cgtacctgca
    41281 agtctaacag atatgcacgt tgggaataca tctattgaat atttgtttac tttatctcgt
    41341 accagaaaaa ttcaactaag ctcaatgaaa gaagaaattg aaacttactt gcatatatca
    41401 ggtgtaatcg tgcggatcaa cgcagggcgt attcaaatta ctttaccatt aggagaaaat
    41461 gatcgtattc caattgatgt accatcaatg atcaatagcg tgttttagaa gacatcacaa
    41521 atagaaacag aaaatacaaa ctaccagttc acaaacagaa aagtaccgag aaaagtgagg
    41581 aatagaaatg gctatgaaat tattagagaa agtcaaaaag agagccgaaa aagctgaatc
    41641 tattttgcta gataaagaac ctaatataaa gcttaatgga aaattcagtg tcaatatgtt
    41701 gaacacaaag gctaaagacc caacagatgc tatttttgga attaagcctg atggcacaat
    41761 tgctcatttt tgcatcagcg aaatgccaca catgttggtt gcaggaacga caggatcagg
    41821 gaaatcagta ttactgaatg aaattcttgt tacagtaatg tgtcactcaa cgcctgatga
    41881 attaaaaata ggaattgtag acccaaaaag ggttgaattt ggaagataca aaaaattgcc
    41941 gttcatgttg gctgatccaa ttacagatat ggatgaagct tatgattttt ttgaatatct
    42001 tgtgatcttg atgcatgaac gttacaaact gatggaaaaa gcagggttac aaaacatcac
    42061 gctatataac gaatatgccg aaaaaaatgg attagataga tttccctatg tgatcttatt
    42121 agttgatgaa tattcacagt tggttggaac acataaagaa gtagaaggtt tgattgttca
    42181 attaggacaa atggcaaggg cagcaggtat tcatgttatc ttagcaacac aatctcctcg
    42241 atcaacagtt gtcactggta ttatcaaagc caattttccg tcacgtgttt gccttatggt
    42301 agcaagtgat ttagaaagta ggattgtatt agatgaaggc ggtggagaaa gtctaagtcc
    42361 aaagggagat atgcttatta agcttgttga tggaagtatg gttagagcgc agggagctta
    42421 catcagtaac aaagaaattg aaacaatctt caatcacctt agaaatacta tgccagaacc
    42481 agaatatgtt gattaccgag caatcgtagc tgaaactcgt ggtgagggcg gtgaagacga
    42541 ggattttggt ggaattggta aagctcctgt aagaaaatct gctaaaagaa atttgaacac
    42601 acctttagca aatccatcat ctaaagagcc atcaattgaa aagaagagtg cgtttgctat
    42661 taagcttgaa aagaacaaag aagaaaaagt cgagcaggga gctaaaacac tagaaaaact
    42721 gcaagcagaa aaactagaaa aagttttaag ggcattagga aaagctgatc ctgaaccgca
    42781 aacctcaaac aacacgaata ataaacagcc gattgcatct aaaaccaaac ctaaagctaa
    42841 tgatccaaaa ggctcagaaa acgtagtgat cacaactgat aaatctgaaa agaaacaaat
    42901 aaatggaagt acttcaccta tcatgcaaaa aatgttaaaa gcaaaaaaac aggtgcataa
    42961 atgatcatcg tcagttcttt tttaagatgg cttactccat ataaatatac agatgaagta
    43021 gttgtgaaac gagcgaagaa aagagataaa aaagcggtac taactcctaa acagatgctt
    43081 gatcatggca ttttaggggt gaaggtttta gaagtgaata aaccgtttga atcaaatagt
    43141 gcaagagaaa agttgcttgg agctgaagcc gatgtcgcat atttttacca tgacaaaagc
    43201 aagcatcaaa tagctattaa attcaatcca aaatcggcat ggcggtatca agcaagagat
    43261 gacttgaaac gtaggaaact tagaccaatg ctctatccag aaggaaaaga agcatttgat
    43321 agaacccaca tcgttcccat tggttttcat ggtacagaat cagataaccg cctattagta
    43381 ggttggaaca gcaatcaaaa tagagttcag atcaataaat ttgagaagaa agtaaggaaa
    43441 ttcaacgatc gaaaaacgat cctatggttt gcagatattt gtaaacagcc ggatggaaca
    43501 gcaaagtggg aagcggtgat atttgacgaa aatggtaaaa aagtaatgtc tgaaacatgg
    43561 catgataaag ctaaatttgt ttggcagtag cagtagaggt gaaaaagatt gctagaactt
    43621 tttgaagcaa atagaacagg ctttaatcaa aaattagaag tgggagaaac tatagaatat
    43681 aaagataaaa actatattat tatcggaatc tataacacga gaattaacag aataggtgat
    43741 ccacgtataa ccagtgactt ggtttgtcaa tctgttaact attcacctga tctgacaagc
    43801 aggtataaga aatacgtgtt attagaatat agacacaaga ttactgatga aattggtgta
    43861 aacaacacac gaaacatatt taagatcgga acagtgattc cttatagtaa caacgaagaa
    43921 aaaatatttt atcagattta cggaatagaa aagtttgaat atgaacatgt cgatctgcta
    43981 gtgacgtacc aaatgcgttt aatagaacct tggtcacagg cagaaattga taaagcagta
    44041 aaattgaacc gattatcaaa atttaacgta ttaggaaatg ccttttaaaa atcgcaatac
    44101 acaaacagaa aaataccaaa aaattagcaa tgaacgtagg taagaacatg acaataaata
    44161 ataataaccc taaaaaatat aatgctcttg tccaatgcta tatcgaaaac aaaattacaa
    44221 tgcaagaagt cgctgatgaa ttaggcaaat caaagagcct agtatcacac gattttaagc
    44281 acaatgtttt tccgaacccg attgagctga ggaaaaaatt tcaaaagaga gtttatcaag
    44341 aaataggtaa gtggattgat gaagggaatg caattgaccc tttaattgaa aaatatcctt
    44401 ttttaaaaag caaaaataaa attcaaaggt taattcgtca aggcgatatt caagctaaag
    44461 aacctgtttt gacaaccaat gatttggcta aaataaatct tcataaacaa attattgaag
    44521 actttgaaaa aaatctttca acaactgaaa ttttaaaaaa atacaatatt ccgagaggaa
    44581 agctaacatc gactcttttt agagaatatg gagaatcggc agttactaaa gcaaaggaag
    44641 tagcgaatga gagaaaaaaa caaaaatagt agtcgatacc tagtagcgac tgtagttttt
    44701 gtttgtgtat tgattttcct gtttgatttt ttgcagattg gaaaaagcat aattggaaat
    44761 acattgagtg caaaggaaat ggttgcttta ggtggtttgt atgaaggaca cttgttcccg
    44821 aatatattca tttctatcgt ttctcatatt aacttgtacc atttaatttc taatttattg
    44881 ttcttagtag ttcttgaaga agcactgaat gatcagtatg agtggttaac attattgatc
    44941 gttttaatca tatcaggatt tctaggaagc ttagttcctt ttctgctaca cagcaacatc
    45001 gtaagtatgg ggcttagtgg aggtattttt ggatggattg ctttatttgc gattgcatac
    45061 atccattttg atagcaagaa acatttatta ctaagtgttt ttgtattatt gataatcggc
    45121 attttactgg tatctacttt tgaatcaggc gagacaaacg tcttgtcaca tgtaatcgga
    45181 tttgtctgtg ggatgatctt gggatttatt ctaaagaacg tttcattgat caaacaaaag
    45241 aattaaaagg gagtgctaaa aatgccaaaa aaaaaagaaa agaaaattcc agtgtttttg
    45301 tctgtctcag aaatgttatc acttcaaata ctgttaagaa aaaagattga aacaatagac
    45361 gaagaagtta gaaataaaag ggctatgtac gaacaacgtg aagcgctaag agaacgaatc
    45421 cactattttg atgatataca cactaaaatc tatgaagcac gtacaaatca cgaagacgaa
    45481 agcaaattag gattagctca acaacgaata tttgaatggc tgaatacgaa tactgagcaa
    45541 gaaccgttaa gagcaattag taatcttttt gaatttggaa cgaagcattg gtttaacgct
    45601 gtagaaaagg atgctgactt acaagaagcg ttcgatacac taagcgagga tagcaaatcc
    45661 atgcgagact tattgatcac ttatctaaat gagcatgaat ttgaacagac gaaagttaaa
    45721 aagaaaaata aaaaatagaa agttgtgatg tatcatgctg tttaccttat taggttattt
    45781 atgtttagtt cttgcttttt ttggagcaat agctatattt gtcggtcagt ttcaagcaaa
    45841 taatccgata atgcgtaaca taggcattgg aattgttatc atatccttga ttgtatttgg
    45901 tgccacaaag atttttggga gtaatgatca gcagtttggt atttctggag ttgataatag
    45961 ttatgctcca gattcattgg gaagagtagt gatagatgga acgtttgaga atgtaacgag
    46021 ctacaaaaat gtttcattga cagtgaagga agatggcaag aaagcatcag acgacgttct
    46081 cgctactatt aagccgtctc aatcacaatt tgaagtgttt tatacagtta aagagaatag
    46141 ccctgtacac aagctgacat tggtttttaa cgttgatgga gaagaatact ataaagatgt
    46201 aaaaataaat aaaacatcaa cgaaaaagat tatcgaatca gcgaaaaaag aagtagctac
    46261 agaagaaagt acaactgaat caagttctac tgtcgaagcg gaactaccag ataaaattga
    46321 ttttgatcct gaaaaagtca aatcgtttga atctgtttct ggttctatgg cagatcggtt
    46381 taacactgaa gttttcaaag ctatcaaaac tgttaaattg gatactgaaa agcaaatgat
    46441 taatgttacc ttattcaatg cagttgaatc tatggatcag gataaaaaag ttacggttgc
    46501 aagagaacta gggaaaagag taattgggtt gtatcgaggt acggcaaaac cagattcaga
    46561 cggttcagat ttgccagttc acgtagttta tgaagacggt aaagtttttg gagactctac
    46621 agcaaatgaa gcactaacga ttaaattagc taaatagccg gaaaattata ataaacaagt
    46681 ggtgtcacac caccatcgca taggtgtgac accttggaga tgattactga tggtagtaaa
    46741 taaagaaaaa gtaagaaagt atgttacttt aaaaatagct tctgttgaat atttagaaaa
    46801 gcgagctaaa gaagaagaaa aaacaagagg taagaaggta acagtttcag agttgttaga
    46861 agaattaatt gagagtgacc aaacaataag acgtgcattt accaataggt ctgttaaaag
    46921 ttagggtgat actatcttta atttcaacca aatttctaat atatgatgaa tagtttcctt
    46981 gtacaaaata tctaattaag agataaaagt taggaggatt cattcaaaat gattatccaa
    47041 aagtttgact ggaaaatgaa attaggaatt agtcttgtaa tattgggatt tattattttt
    47101 ttggggataa aagcacaaaa aaatcaatct acttttgaaa ctatgtcttc tcaaattatt
    47161 gaggaatgtt ccaaaattta ttattgtgag aacaaaactg aagaatctaa tggcttttat
    47221 tatatcgatc aaccacatga tgttgttata aaaatggagt cacatgaagt aaacgaatgg
    47281 attcaaagaa gtactaatgt atcaaaaaag ttagaaagat attctcaaac gtttttaagt
    47341 aaagtcattt tttcaaattg caaaaataaa gaaacgtctc aaagagtagc tagttcttta
    47401 gaaaatttaa aattttctgt ttcaaaaaaa gagaaatttg tagatttacg aaaataaact
    47461 atcgaaagta gtatgattat gatcttaaaa tatcatctta agagaagaat tacgattgtt
    47521 tataggattt acaaaatgaa taagtttgaa gagtgatttg gtcgcagact agatcactct
    47581 ttttgtataa aaaaacttta cacttatttt tgagtgtgtt aagatttttt atatagagtg
    47641 acggtttctt gtcagagtga atgataacca tcaatattgg aggaataata agtggaaaac
    47701 aataatgata ttagatattt tagcattggg gaaagagtta caacagtaag tgaattatca
    47761 aaggattata gagataaaga aggaacgatt atttctctta aaaagaatcg aagaggtgtt
    47821 tggcaatatg ttgttgattt aggggatggc gttacagttg agtgtaaaga tagtcaactg
    47881 atcagaaatg atggcagtca ttccattgaa aaagcaattc ttgtattccc aaaagtatca
    47941 agcaagatta tgaatgactg gttgcttgga aaatttggtg agtacaataa aaaagaaatc
    48001 gcagaagtga tcggcaaatc ttatccaaca gtattagggt atctaaaaaa gataacgaac
    48061 aaagaagcga aagttgagga tgttttaaca gtaagagaac ttcagtcatt aatcgaatat
    48121 cggaataaac aaataacaaa tcctgagtac cttaaaaaag aagatggtct attgaaacaa
    48181 ttggaacagg taaataaaat ccggaaaatg caaaaggtag ctcctttaag cctagataac
    48241 tttaaaaaaa tctatttgaa agagatcgaa aaagactaat gtggagtgtc actttaccgt
    48301 ttcaacctgt atctgcacca agaccaagtg caagaaggaa tgttgctgat gcaactaatg
    48361 acgtagcaga gaaaaggatt tcaacctatt atgataaaaa gtatctcgat tatttgaaaa
    48421 aaataaaaag ctttatcgaa gatcaaggtt tgttagatga tgaattttac tcgatcgtaa
    48481 atgatccgat gggtgcaatt atggaagtgg acttttacta tcagatacca aaaagctata
    48541 aaaaagtcta taacattatg aagacgacag cgccagattt agataattta gtaaaaagtg
    48601 ctatggatgg tattttcaac atctcagcta tacgagatag ccatatcaca gggttaattg
    48661 cttttaaata caatgtggca aacgaaggaa aaacagttgt gaggatcaag cgatattcag
    48721 aatttgagtg ggatacttct gaaggattga acggagatat ttgggaagcc acatttgatt
    48781 tcaaaccagt agcaacgcca agaccaaagt ctaaatttag aggaaatggg attatcactt
    48841 actatccaaa agagtataac gactatttgg aaaatatcaa gaatacgctt aaagagaaag
    48901 atttggtaaa tgatcaactg aaaaaggtaa tgaatgctcc tatgggggtt atagctcaga
    48961 tagattattt ttaccaagtg agaaaagata agaaaaagct tgattcactg atgcgtactt
    49021 cacagccgga tattgataac ttagtcaaag gaacattgga cggaattttt aacaaggaaa
    49081 ttggcatcaa agatagcagg gtggtaggtt taatagcttt taaatacaat acttttgaaa
    49141 agtcgaaaac aaacgtgcga ctacaggaga tgggctgatg aataataacg aaaaaattct
    49201 tcatgtactt gatagctttg aaacaattca agaggaacta aagaaatatc gagatgtttt
    49261 ggaacaaaga tatgattttg tcaatcagca aaagagtaat cacatggatt tcattctcaa
    49321 tatgaatgac ttgaagaaga aattagttga acgaaaagaa caagaaaagt tgatcaaagc
    49381 ttactttgaa ctcggtgaaa aagaagttaa aaaggcaatg gaactgaatg aagatcgcag
    49441 ggttttagat cagctgttag aacaattatt ggtgatgttt caaaaaggac gaatagatga
    49501 ggatttaatt gaagaagggt tgagaaagta tcctgcaaac tcaggtatcg gaatagtgct
    49561 gaaagcgatt gatgaagaag aaattgaagc tttcataccg ccagaggatt ttgaatcggc
    49621 aatggaatat ataaaatatt atagccaagg gatcactgct tttagagagt ttgatcctga
    49681 agatgttatt catgacttga acaacctaaa agaatggtgt gaaagttatg gagtcgatga
    49741 ttccggattg gactacttga tcagtattat ggaaatcgaa gaagagatgc cggataagcc
    49801 tgatccaaca gatattttag aattgatcca tgaagctaga aatccaattg cctatatttc
    49861 tagaggatat actgtattgg aatactataa gccttatata tcagcgatga accatttaag
    49921 acgtgtatta agggaaaaac gtgaataccg ctcagtgttg aatgcaacga atagattaga
    49981 aaaagctgtt tcagagctag atgcttatta tcgtgaacat tacctgcaag caggtggtat
    50041 gccaagaaat acgaaagcaa atatcagtag gtatataaaa aaagctgagt aggcggagtt
    50101 agcccataaa atggcaaaag gtaacctgaa aggggcattt tgaatgaaaa gggatgtttt
    50161 tgaattgtac gtattagaac gtctagaaga cggcatgatg gcacaagaga taattgatga
    50221 aattgatgat atgatcagca gatttggtca attggagttg aatgatggaa acaaaaattc
    50281 ggtagtgcta aaacaatttt ggttgaacaa tttttcgtat aaggatttta tcaaagaaaa
    50341 ggcaaataca ttgtactgac taaattcacg aggagcagtg atgagagctt attgctaaga
    50401 gcagttaggc tcttttttgt ttgtgtaaaa ttatttgttt tataatacac atttatacac
    50461 aaaaaaatat tgacagatag tacacaaatg tggtaggata tatttgtaag caagttagat
    50521 taacaagtta aaggaagagc agttatgaaa aaagaagaac taatagatat atttcaaatt
    50581 gttgaacgag caaataatat gggaattatg ttttttgatc gtatttcttt aaagatggat
    50641 ttaacagaat taggcagaag tcgcccatcc tctataggtg ggtgatgaat gccgttcggt
    50701 atgagggtta ccgttggtaa ctcgaagacc gacaactaag gcgtattgcc tttttatttt
    50761 gtcccatgtt acaatcagtc tatacaagaa atgagttgat ataacatgga attagataca
    50821 aataatcatt cagtatttct tctttattac caccttgttt tagtaacgaa atatcgtaga
    50881 caagtgattg atgatgaaat atctgattat gccaaaacta cttttgaaag aatttcagaa
    50941 tcgtatcaca ttactttagt ggagtggaat catgataaag accacgttca tattatgttc
    51001 aaagctcaac ctaaaacaga attgacaaaa ttcatcaatg cctataaaag tgccagctca
    51061 agattgataa aacgtgactt tccaagagtc aaacaatttc tttggaaaga aatgttctgg
    51121 tctaaaagct tttgtcttct gacaactggt ggcgcaccaa ttgatgtgat taagaagtat
    51181 atccaaaatc aaggaaacaa tcataaatag aaagtaggtg aactttatgg aacaactaaa
    51241 agcatacaaa ttcagaatct atccaacaga ggaacaagaa atcttctttg ccaaatcttt
    51301 tggttgtgtc cgtaaggtct acaatctaat gcttgatgac cgaaaaaagg cgtatgaaga
    51361 agttaaaaat gattcttcta aaaaaatgac ttttccgaca ccagctaaat acaagaaaga
    51421 atttccgttt ttgaaagaaa ttgatagcct tgctttagcc aatgcccaac ttaatttaga
    51481 taaagcatac aagaattttt ttcgggataa atccgttgga tttccacgtt tcaaaagtaa
    51541 gaaaaatcct gttcagagtt atacaacgaa taatcaaaat ggtacagttg ctttgattga
    51601 tagtaaattc atcaaagttc ctaaattgaa gtcattagta agaattaagc ttcatagaca
    51661 accaaaaggg attatcaaat ctgctacaat atcacgtcat tctagcggta aatactatat
    51721 ttctttgttg tgtaaagaag aaattatcga attacctaaa actaattcca caattggtat
    51781 tgacttaggt attatggact ttgcgattct ttctgatgga caaaaaattg ataataataa
    51841 attcacgtcc aaaatggaaa agaaactaaa gcgtgaacaa cgcaaattgt ctaggcgtgc
    51901 tttattggct aaaaataaag gtaccaatct atttgaagct aaaaattatc aaaaacaaaa
    51961 acgcaaagta gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa
    52021 gttgagtaca gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa
    52081 aggtatgttg cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt
    52141 tgtgactaaa ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa
    52201 atggtttccg tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct
    52261 tgaaattcga gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc
    52321 tagtatcaat attctgaccg aaggtctaag actacattct atgggattgg cttagatcca
    52381 atcatcaaga accgtaggaa ctacggggat agcttggtaa ataagagaca ccgctgttag
    52441 taaagaaata cgctatcaag tatgctctat tcccaagaag ctcccacttc aagcgttaag
    52501 aaccgtcagg tttagctaag tggtgagtag ttcacgacaa caacgattat gatcttaaaa
    52561 caatcgttta tgtaattggc aatcttacga ataattttca tgcaataatg acaataaaaa
    52621 atgaaaaggg gtaaaatcaa atgaaaaaat ttttagtagg aattctattc acaatggggc
    52681 tagtattatt atcaccttca gtttcagcag aaagctctat ttccatgtat cgtatgtata
    52741 atcccaatag cggagagcat ctatacacta gaagcgttgg agaaagagac aatctgaaac
    52801 gttatggatg gcattacgaa ggtgtcgcat ggcaagctcc aacaagtggt actcctgttt
    52861 atcgtttgta taatcggtat aacggtgaac atttttacac agttgatgcc ggagaaagag
    52921 ataagatttc acacacagga tggacgtacg aaggtgttgc gttctattcc tacaacggag
    52981 caaatagagt tcctgtaaca cgtttatata acaaatacgt gaattggcat cactacacgt
    53041 tagatcaaaa tgaaaagaac gtaattagta aacaaggttg gaagattgaa ggtacaggct
    53101 ggtatgcaat gccaaacagc gtaccaaatc ctacacctgc tccaagcact gaaaaagtgt
    53161 tgaacgttcc tgttgtatgg caaggaaata caatgttatg cgaaggagct tctttattag
    53221 aaggtttaca ctacaaaggt gtagccacaa atcaaagctt aaccagtttt gtaaactata
    53281 tgccaaaagc taatgacaat aatccttatc atggttactc aggagagtgg cgtcataacg
    53341 ttaatggaac gtatcaaggc atgatggctg acccagtagt taaatgggca aaaaacgttg
    53401 gcggtaatgc cgtcaatatc actggttcag gaacgaatgg aatcaagaat gaaattcgca
    53461 atggtaatcc ggttgtaact tggattactt ataactatgc tacgccagag ttcaaacaaa
    53521 tgccttgggg tcgtgcagta tggaatggac atgtagttct cgtggatggc ttcagaaatg
    53581 gtgcatacca tgttgttgac cctgtatttg gcgcaaaatg gatcaatgca agcacgtatg
    53641 agagagcatt taatgtgact ggaatggcgg ttgctgtacg ttaattgata gaattatcaa
    53701 ctaaatgaaa taagagctta attactgaaa tggtaaatag gctcttattt ttttagagga
    53761 aatttttgta atacgaatct ataacaaaaa atattgaatg tagtacacaa aagtggtata
    53821 ttaaaatcgt agagattatg cgaagaggtg attttgatga accaaagaag aagaaaaagg
    53881 ttagaagaaa taagcgagcg actttccaag ctaaaggatg agttagaagt aattcaagaa
    53941 gaagagtaca aagaaaatat acctaaaaat ctacagggat cagaaagata tgaaaaagca
    54001 gaagaatccg ttgatcaact tgaagaagct gttgatggtt tatccgacat attagaattg
    54061 attgaagata tagctagcta gagatgatta atgaagattt caggagtgag aataaaatga
    54121 ttgatatttc actgatagag aagctacttt tttcaaataa gtacacagcc aaagagttgg
    54181 ctacaagatg gcaaatatcc gaatcagcta ttaaagccta tcgtcaaaat aagggaagcg
    54241 taggatggcg tgattggaaa ggaatcagca ttggaaaagc agaagacata atgaaacgtg
    54301 aaggatttca agctgacaat gattctaaaa aagttgaata gtttaatagt cgccaagaaa
    54361 agtaccagga cgaggggaaa ggtagattac aaaggaaaac acttttaaat aaacttcgca
    54421 aaagcatcag gttatgagtg gctagggcta tacgaatgtg atgaaaacaa agggctttaa
    54481 tgtcaaagaa aacgcaatag ggggggaaca aaatttttaa aaaagatatt tatgtttggt
    54541 ttaatggaaa aaaatatatg actactaaca aaaggtggtc agagctagta caaaatacag
    54601 ttaaaaaagt catgccagat ggatatcatt tcaactatat acaatgctca caaacaactg
    54661 aaagtattta tttttcaata ttaaatgaga atagactcta ttatttcagg gtaagttcac
    54721 accataggaa aaagagagaa gataatgtta cgacattttt atcgggaaaa tacaatggct
    54781 tcaaagagtt aagtgaagcc attggtgagt atctaaaaag taatagattt gtcagaattt
    54841 ctgacaaaca tatattgatc ttgttacttt atttgaataa tagcttcaaa ttgttttgga
    54901 gagacgacac tttctactat attgagaacg gcatggatat ttattctggt atcaacggca
    54961 tattaaaaca ttatattaag gcgttacttc gatatggggt tctttatcaa gaagatttaa
    55021 gtaaccaaat taagattagt aattctggaa agtcattact ggcaaaatat aaaaaattgc
    55081 tttctcctat ctacaaagga atagatatgg aagctgtaaa ttctgaaact ttatttaatt
    55141 tagttgttga tgaaaagttt gcgaatgaat tttttaaaag taaaaaaatt gaaagactaa
    55201 ataacctgtt tcctgaaaat gcaataaaag cttatgtaga taataataaa tcacgattat
    55261 acaactggtt tattcccaaa cggttgcgag gaaaaatcaa aattggcgat caagtgaaag
    55321 taattaatct aaatcatact aagatcgtta ccgtaacgga gttgtatata gctgaaaaag
    55381 aagatattac aaaaatgaaa ccagttatta aaatactaga taacaaagag tgagtggaat
    55441 atatggtagc aaaaaagaat actctaaaag aagcttctga aaaatatcaa gatatgaaaa
    55501 gacgaggatt aataccaaag gacaaaaaag gtatatggag agaatttgtt aaggaagtca
    55561 gtagtgatcg aagtggcggt gactttgttg gacgatatac agcaaaaggt tatagcaggc
    55621 gcttaaggat cactgttgaa tatggaacga atgaatcagc tacagagctg aagcaaaggt
    55681 acttagatac acgaagagaa gcttcaaaaa aatatgatga tttcaagagc agaggtctaa
    55741 ttcctaagaa gaaaaagggg atttggcgtg agtttttcaa agaagaagat agcaatcgga
    55801 ataagggaga cttcattgga cgatacacag caaaaggcta cactaagaat ttagggatca
    55861 aggttgaata cggaactggt gaaagttcat gggaattgag aaatcgctat ttaaatacat
    55921 tgttagagaa atataaagca gaattattgg agttgttcga tgttaatgat tttatcgaga
    55981 tggctgaaaa gtatggtcat gaagaaggtt ttatgatcaa tgacattatg gttattgata
    56041 attttacgga tttattagca cttgcgaaaa aagcaaggga tttaagagaa acgcagatgt
    56101 atctattcag aaataaaaac ggaagaaacc ggagaactga atcgagtgag attgaagatt
    56161 actatgatgc ctttacacac gatctgggag cctttgtaga cgagataagt ggtgtaatga
    56221 acaaatatag ggtctagaat aaaaaagccg gagatgagca gataaatggg aaacaatagc
    56281 atatacacac ctgaaatgca gaataaaatt aaaagacttg tcggattagg gtggatgaca
    56341 agaggaaaat tagattcttt tagtacgatc aaatatcttt tgatggacat ttaccgtcag
    56401 aacaagcaaa caggaataca ttttttgggc tatgataagc cggaagatgc acctttcttt
    56461 gttccaagtt cagcctatag agccagtacc tccggtagca tgtataactt ggatttgttt
    56521 gaggaaggag caaagatgat cgaatatgat ttcaacgaag cctattcgag gatcatgaga
    56581 aattatcctt tgccgtcaaa cacttatttg aaagcaaaat ataatacaga tcaagctatt
    56641 ttgagagcga taaatagacc aaaagtaaga ccgtatgaaa atttaaaaac gtatatgttc
    56701 tttttggtta attttgaagg aacagccaaa gaaggaacat atgctaatcc aaaatcacag
    56761 tcgatgtttg cggattatgg cgaaaatccc aaaacagcta atgagcctat ttggttatcg
    56821 gagattgagc taacacttat ccttgattat tatgatatta aagagatgga agtcctagat
    56881 agccacacat ttttgacgaa aaaaggatta ctcaaagaat attttgaaag aatcgagcca
    56941 ttaaaaactg atcctgatac gttgaagctt tataaaaatc ttagaacgaa agtatttggt
    57001 gctatcggac aaaaatcatt aagagaagga gaaacaagca ccttcgataa atacagtatg
    57061 tataatcgag cgtattcctc catggtagca ggcgtattta gagatcgtat ggttagatat
    57121 gaacagaaat acgttcatag cgcatatggg ctattaaaaa ttcgtactga tggattgtat
    57181 ttcagatccg aagtaccaga gtttgaagag ctgtataaac ttggagtagt taagaaaaaa
    57241 gttcatacaa tatccaaaga agaagtcgaa aaagctttag aatttaaaaa caaaggattt
    57301 gaaaataagg gctcctttgg gaaatctaaa gatgaagtta agggtgttgt gatagacgat
    57361 gatttcgagt ttgattttga ctaaatactc tttggaaaag atggtaggag gtaaatatga
    57421 agaagaaaat tgtggaagga aatgtaggtg ttattattct aaaagattca actgactatg
    57481 ctaaatcaat ggcactaaaa gacgaaaaag ttgcacgcat ggataaagat ttagttgaat
    57541 ttctgatgga tgatacagaa agattaaaag gggatcagtt tttgagttta atgaaagaca
    57601 aaggcttaaa cacatatggt ttatttgatt ataagaaatt agctatagag tgggtaaaag
    57661 aaggagaaat attttttatt gaagaatggg aaggtactga gaacttagtt cttcatcagt
    57721 atcttttgaa agcttaatct aagtaaaaca gttctgacta gttatgcttg tcagaatttc
    57781 aaaggaagtt ttccataacc atcatcattc aaaaataaag gatttgaaaa taagggttcc
    57841 tttgggaaat ctaaagatga agttaagggt gttgtgatag acgatgattt caagtttgat
    57901 tttgactaga tttttttgca atgtttaaga gtaaacaagg taagaactaa gatcatgaag
    57961 attgagagta aagaagatag aggacgaatg tatgagaaca cactatattt atttagaaga
    58021 taaaattgta gatgaaattc cggcaaaaag tcgagaacaa gctagaaaat tatttattga
    58081 aaaatacaaa gagatcaatg gagatagtga agttccaaaa gtggtcgtaa cagttagaaa
    58141 aaggcaaaca aaaaagagaa gtacgtttca tgtcagccct gatatatata atcttataga
    58201 gcgacataga agtgaagata atatttctat ctctcaatat attgctacag ttattgatga
    58261 attgatttca ggaaagtatg actatgcttt tgattttgag ggtgaaaagg attacaaaag
    58321 tgttgctgtc tttcaatctg attttgagaa gctaaaaaac tatgctggca ggagaaatgt
    58381 taattttgca agactactag aagagttcta ctccgaagag ttgggagtag gaaatgaata
    58441 caagagagaa acttatgcga aattgtctca taagttatcc caagcgctta aagaagtgac
    58501 agaagttaaa gcggaactag atgctaaact tgaagaagtg aaaaaatatc aaacagagag
    58561 gaagaacaac atgaagaatc aagtggaatt tgacgaacag aaagaatttg aaaaagcaag
    58621 aaaacgctat aacaaaatta tgaatgaact tagctatgaa cacttaacag ttcatgaata
    58681 attgagtgag ggtacagaaa aatatacgat cgcagatatg gttaatgaag tggaaactct
    58741 tttagcttct ttctttgaaa atggtcacgt aaacgatgaa tggcgaaaag aagaacctaa
    58801 aagggttaac gcttatattg ctcgattaaa aaggtttatt gataaatata aggagaatag
    58861 tgacaaattt tctaaagata aataaggaga gagtgtgatt acatttgcca gaaatcgaag
    58921 gaatattttc gccaaaaata ggtaaaaaac agttagattt cagcagtttt ccgagcgtaa
    58981 atagagatta taatctaggt gatgaggtac agatactaaa tattgatttc aaagaactag
    59041 acttcgctgt tgctgtttcc aacaaaccca aggcattgga acgagtgaaa aaaatatacc
    59101 aagagaatga tcaaaatatc aaaaatatga tcaaaaagta tagacgagat aattcaaaag
    59161 ttgaagacgt tttattcaac ggtacggcaa aacatgattt gaatgtttat atggcattag
    59221 gagtggcttt gtactgtaat tcaattaatc agacagatat tttggttaat atcgtgagga
    59281 atagctatca aaaaatatta aaaataagta gcgaaacaaa cccttattat gcaatgaaat
    59341 atcttgggga taatttatta aatgataaaa aattgatgca caacactgaa gagctgttat
    59401 ctaatttggc tgcgattaac tttctattca aaacaggttc tgaagattat tttatagata
    59461 acgtactaaa aggtgcttac ggaacagcat tttatccgct ttacaatatg aaacagcata
    59521 aagccgaaca aaaggataac aaacttgaaa ttaaaaagat gaaagaacta ttaggtatag
    59581 gatttgtaaa acccaattca aaagtcacta ttgcttcgtt agcaactact aacaatgatg
    59641 ggaaaatagt aaatgggttt gacgattcag atatagatat attgtcaaaa tcatattttt
    59701 ctttgtatgg agattttgca gatttgatgg gtattgatag ttacttagtc aataattttg
    59761 agatcaaggg tagcgagctg aatgatattg tgtatttcgt tttaatctct ctatatgcaa
    59821 ttgatcagaa taccgagtac cgacaaattg actatttgct agttttttat agtttgttat
    59881 atcagttcgt tttaactcgg ttgtttaaaa atgctaagga agaattgatc ctgaattctg
    59941 attatgaaat agcaaaacaa attgcaagta ttagaaaaga aaacaaatct gaagtaatca
    60001 aattaagaaa agaattaagt attgcgagta aagaaaacgg tcggttagaa tctttagtca
    60061 aatcggcaaa aaaagaagag gaacttttga agcaagagat taaagaatta aaaggaatca
    60121 gaaaagaact tgaacagctg aggtttgaaa ataaagtatt aaagcaattg caggagcaag
    60181 aacatagaca atcattaaat ggtaaaactg aagagccttc actgtctgaa atgatagctt
    60241 atctaaaaca taaaaacatt cttttagtgg gaggacatgt aaattttcaa aataaattaa
    60301 ctgaactatt accaaatatt aaaatgtttg atgtaagcga aaataatgga aagatactta
    60361 aaaatttgaa tacgtgtgat gcgatttttc tatatacaga ttacttgaat catggtctat
    60421 attatcgtgt tatgagtgaa atttctaata aagataagat attttatttg gacagtcatg
    60481 tgaatatgag cttaacaatt aaacgtattt atgatctttt atatgtttat aaacattaat
    60541 gaggtgctaa aattgacaac aataactatg acaaaaaaaa tagaagtata tgttgatgga
    60601 tcacaagaag aaagggattc cttttttgat tttttttgga aaaatagtag agaatatgta
    60661 aaagcgttga atctggtata taaacagcta atgtttgaag agttgataaa agatgcaatt
    60721 aaagaaatgg atcaaggtta tgctgagaga gaagaaagta ttcaaaatcg gattgaaaag
    60781 ttagcatata ctgatccaat agatcaaaaa aaacttgata aagcaaaagc tgaattatct
    60841 aaattgagaa atgaaaaaaa taaagaagcg agagaaatat taacgcaagc gatagggttg
    60901 aagagtcaaa cgagaacacg agatgtagca aaaaaattag actttgactt tggagatttt
    60961 gttgattccg caaatatgaa agctagtaaa gattttggca atgattttat cggaattgtg
    61021 accggacaaa gaacgcctag aatatataaa aatagaaaca aatatggatt actacctttt
    61081 agaggtcgag atattaaaat ccataaagat gataagtttt atatttattt acctaaaggc
    61141 tttaggttta aagtgaattt aggtagcaag ccaagaaaag caagagatgt tgcttcagtt
    61201 ttacaacaca ttatggatgg cgattacaaa ttaaatcaaa gtaatcttat ttttgatgga
    61261 agaaaattat tttttaatct aacaatttct tttgaaaaaa gctataatga aatggaattc
    61321 aagaaaggta atgaattgat cgtaaacttt gcagatttgt gtagcggtga atgtttaatt
    61381 aatgataaat ctgtaatgtc ttttggtgat agccaatata taagaaactt caaaagtaaa
    61441 attttagcaa tgaaatcaaa agaacaaagc cgaggagtct tttctaaggg cggtcatggt
    61501 cgaaaaagaa aattagatca agatcgatgg gaagcaataa agaaaagaga aagtaatttt
    61561 gttaaaactt ataataatca atgttctgca aaaatcgtta aaactgctat tcgcaataaa
    61621 gctcaaatta ttcgtatcat tgaaccagat aaggcttatg gcgaatgggc ttactatcaa
    61681 ttgaaagaac aactagtaaa caaaggaaaa agatatggga tagaagtcag aagttagtaa
    61741 attaaacaat cgttgatttg gcaacgaaat agtgagggaa aatccactca ctgaagggta
    61801 aactccgtca agttgtgtga ccagacggaa ggacgaatgt tgttgaggtt ttagaaccat
    61861 ataaaacagc atgtttctca aatttttagg ataagggaaa ttgctagcag tttgttttag
    61921 aaccatataa aacagcatgt ttctcaaatg agtactttaa attaattgat ggcgttcctg
    61981 ctttagaacc atataaaaca acatggattt aaaacaagaa gtaagtcagt tctcctttta
    62041 ctttagtaag gaaaaataaa gtattctcaa taaaacttaa aataagcaaa cctttgtttt
    62101 aatagctaat cgaagtaaaa cccaaagcca tatgaacccc tgaatcagcg aaagtttatg
    62161 atgatttgga ttactaatag tttaggaatt agatggtaaa tctaaattaa acaatcgttg
    62221 atttggcaac gaaatagtga gggaaaatcc actcactgaa gggtaaactc cgtcaagtta
    62281 tgtgaccaga cggaaggacg aatgttgttg aggttttaga accatataaa acagcatagt
    62341 tctcaaattg tttaaaatga ttgtcaagtt aaaaaaatct gggatcatat aaaatagtat
    62401 agttctcaaa tatgattaga aaccctatta aagagcaata ttaagccaac ttacttaaat
    62461 cgtttaatta agaacaataa tctcttttag tcagactttt agtctgactt ttttgtattt
    62521 ccaaaattta ttctttacaa aaacgaacat acgtttgtat aattgcttgt gaatggggga
    62581 ataaaaatgt ttgattacag tagagaaccg gtgaatgact attttttaat cgacatgaag
    62641 tctttctatg ctagcgtgga atgtattgaa cgaaatttag acccaatgac tacaccgtta
    62701 attgtcatga gtagatcgga caacactggt tcaggtctga ctctagcttc ttcacctact
    62761 gcaaagaaaa aatatcatat tactaatgtt agtagagcta ctgatttacc ttatccatta
    62821 ccaaaagaac ttcatattgt tccaccacga atgaacttat atataaaaaa aaatatggaa
    62881 gttaatcaga tttttagaaa gtatgtcgca gatgaagatt tattgattta ttcgattgat
    62941 gaatcaattt taaaagtgac aaaatcctta aatttattta ctatataaat tgagttaaat
    63001 tgtattcgtt tttcctccta taggcgtata ctaaagaaaa cacttgagga gtggggaaca
    63061 tggaaacaga acgccaaatc cgtgaattgg aaaaagcgat gaatacgaca gacaaccgcc
    63121 ggttgtacga gcgtttcctg gcagtcaagt tggttcttga aggccacacc cggaaagaag
    63181 ccgggcacac catcggccgc gacgagcata ctgtcagcca ctatgtgaaa aactactgcc
    63241 ataatggaat ccaaggttta gtctccaaaa aacaaagcgg acgaccttca cggctgacag
    63301 atgaacagga agcggaactg gtccaaatcg tcgcctacca cactccggag gaagtaggtt
    63361 tcaaatcccg tgccaattgg acattggcga ttgtgtgtga cctgattctc cgggaatgga
    63421 gttatggata tacgcaaaaa ggcgtggcgg acctccttca ccggctagga ctaagctgga
    63481 cccgtccgac gtataccctc aaaaaagcgg attccaagaa acaacaggta tttttggaag
    63541 aaaccttccc gagcctaaaa aaaaattgct gaatagcgat attgaccacc tcctattcga
    63601 ggacgaaacc atgatccggg attaccaagc cattggctgc acctggtttc tccgcggcca
    63661 ccagcgaaaa atccccactt atggacaaca caaaggggta aaattgatag gcaccttgga
    63721 ttatgaaacc ggtcggatca tttgtacaga agaaggggca tacgacgcag cggccttcct
    63781 ccgttttctg gagcggacgt tgcgggaata ccccaccgga aaaatcgtga tggtattgga
    63841 taatgccctt atccaccacg ccaagctgat ccagtctttt cttgaagaaa acgctaggcg
    63901 cctggcactc atcttcctcc ctccctacag ccctcagttg aacctaatgg aaggcgtttg
    63961 gaagtggctc aaggaatcgg tcatcaacaa tgtttttttt gaccacgtcc agaaaatcaa
    64021 acagtcggtc cgcggtttct tagccgatgt aaacgagcgt ccccttgagg tgattgaccg
    64081 actgtgcgtg cggatgtaaa gtatttaatt caacctatat agttcaggaa caagaagcga
    64141 gagaagaaga gaattagcta aaataatcaa agatgagatt cagaaagaaa caggtctaat
    64201 agcaacagtc ggaataggag ataacccatt attagctaaa cttgcactgg acaatgaagc
    64261 gaagagtagt aaagaattta tagctgagtg gacttatgag actgtacctg aaaaaatatg
    64321 gaaaataaac gagatgactg acttttgggg cattggatca cgcatgaaaa aaagattgaa
    64381 tcatatggga attatgagta tagaagattt agcaaattgg aatccctaca caattaaaag
    64441 tcagttaggt gtaatcggac tccagttata tttccatacc aatggaattg atcgtacgga
    64501 tattgctatt ccaccagaac caaccaaaga aaagtcttat gggaattcac aagttctacc
    64561 aaaagattat acgaggagag aagaagtaga actagtagtc aaggagatgg cagagcaagt
    64621 agccattcga attagacaac acaattgcaa aactggttgt gtacgcttag caattggtac
    64681 gtcaattttg gaagaaaaat caggtttctc gcaccagatg aaaataccaa ttacagataa
    64741 tacgaaagaa ttacaaaatt attgtctttt tttattcaat aagttttatg aggggcagga
    64801 agtacgacat ataggagtaa cttatagcag attagtatac acagattccc tacaattaga
    64861 tttatttagt gatccaagaa aaaagattgc tgaagaaaat ttggatagga ttattgataa
    64921 gattagacaa aaatatggat ttacagctat tatacatgct tcatctatgt tagaaggtgc
    64981 aagaagtatt acgagaagca ctttaatagg aggacacgca ggaggattag gaggtttgca
    65041 taatgattga atataacgat agaggacgtt taaaatggtc gggattttat ttgtctgatc
    65101 atactgaaag aatcaatgca gacaatgtac aacgtgctaa tcataatttg gcaaaagaac
    65161 aaatgacgac tgaagagatt gcgaaaatac tgagaactgc tgtcataaaa aatagacccg
    65221 tctgcattca aaaagaggaa cgaaacgctg aaggttacta tccagatgat gtagtaggaa
    65281 aaattattgg atatgacgag cttggtgtat ttgtggaaga agaaaaagtt cactatgatg
    65341 aaattaggaa tgtttctttc tcggaattat taaaatggag tcagatatga acattattaa
    65401 aaaatacgaa ttcggttata ttacgtatga acagctaata gaggaattat ggggatatgg
    65461 tcaacaatta attaatgaag tggggattga ttgcttttgt ttctatattg aatccggagc
    65521 aggataccat aagaacagat actatatatt tccatatcca ccaaaatagt ctcttagata
    65581 tttttaaatt ttctccaaat actttcaatt attgtgaaat atttcccttt aattaatcaa
    65641 attttttata aaagtaatat ataaaataaa ttgcttgaag tattatattt agatatcata
    65701 atttatggaa gaaaaattaa ttaaaaagga tgagattata atggggttac tggttccgag
    65761 agctaatact tatactatac ctttaacgaa acgccaatta attgctaaaa gatatcaaag
    65821 gattactaga gccatcaata gagagttttg gaattctgaa agtgatactg ctcacagttt
    65881 atacgtaggt tcttatggga gaggaacggc aattagtact agtgatatag atataatagt
    65941 tgaattaccg atggcagaat ttgacagatt caaaaattat ttatcaaatg gcccgtctaa
    66001 gttattacaa gttataaaaa acgcatttca ggaaatacta ccaaatagtg atattagagc
    66061 tgatggacaa gttgttaaaa taaatttcca tgatggaatc aaatttgaaa tagttccagc
    66121 ttttaatgaa aaagattatt ggggtgagtc aaaagggttt atttatccag attcaaacat
    66181 gggagggaac tggaaagcta caaatcccaa aaaagagcaa gaagccatga aattaaagaa
    66241 tacaaaaagt aataatttat tatatgctac gtgtaaacat tttcgacatg tacgagatac
    66301 agaatttttc aggaatagta attgacagtt tcgtatatga ggctatggga aattggaaat
    66361 tcgttgaaaa taacagtggg ggtcaaaaca ttagttctgt atcttatgag acagctttat
    66421 tagaatacta taactcacat aaagttatgg gcggtttaaa tttatactct cctggaagca
    66481 atcaatttgt taattctgat agtagtatca tatgtttaga aaaagtatta aaaaaaatag
    66541 ctttataaag ttttatggag gaacaacatg ggagacgaaa aaaagcgctt ggaagttcaa
    66601 ttacgtgaag catatggacg agtaacgtat acttacacca ctcatttaaa gcaagccgat
    66661 aatattattt ctgacaataa aattttaagg tgtcttcaaa ttggtttgtc agcccttact
    66721 actggagggg tacttagtac cattattact gataatagtg agttaacctt tgttgctgga
    66781 ttatgttcaa caatttctct tggattaaac ttatacttta agaattttga tcttgctgaa
    66841 gaagctaaaa atcatcaaat tgttgccgat aaattatggt tgatcagaga agaatacgta
    66901 agcttactaa cagatttaaa tcgtttaagt gttgaagata ttgtgaaaaa aagagatcaa
    66961 ttaatgaacg aaactcatga agcatataaa aatgccccta aaacaaatag taaaagctat
    67021 gaatcagctc agaaagcatt aaaatctgaa gaagagcaat tttttacaga agaggaattg
    67081 gataagatgt taccagagca tcttagaaaa aagagttcta aatattgaac tcttttttta
    67141 tgcttaaaat tctcttgtaa tttttctatt catctatatt taagaagaaa tatgatgata
    67201 gaaacatctc ctaaagccac cgcaagccgt tctaagcata gcttagcccg acattgctag
    67261 atatgctcat ctcaccatga acgtttccta aagccaccgc aagccgtcct agccattgcc
    67321 tagtccgaca tcgctagatt agtgcatctc gccataaaag ttttctaaag ccaccgcaag
    67381 ccgttctaag catagcttag cccgacattg ctagatatgc tcatctcacc atgaacgttt
    67441 cctaaagcca ccgcaaaccg tcctagccat cgcctagtcc gattttgctt gatcggttcc
    67501 atttctgttt atttagtggg tcaacaccgt aatcttaaat agccatcgcc tatttaagat
    67561 tactaggtct gctttgaagg taaaaagtct ttcattcttc aagactttta ggctttcaag
    67621 ctacgcctga aagcattgaa attcatcgct ctttatttgg ttttgccatt tataattcct
    67681 tacgcccatt atctttttcg cctgtcatac cttgtcagaa gtgtttagag cttatctcat
    67741 ctttggatta atacaagtgg cgtaaatttt tttctaaacg caagcgttac gaaaataatt
    67801 tacttaaaca cttgtattaa tccggcagat aagaacgcat tctaatcact cccgacaagg
    67861 caagacaggc gaaaaagata aataaatgaa cgaaaggaag aaacataaaa tgcaaaacca
    67921 aatagcgatg aagaaaaaac cacctccctc taaaacaatc caaacaaaaa agaattttga
    67981 aaaaccaaaa atcaaaaaca gaaagaagcg ttcaacatga gagatagaat tttagaagtt
    68041 aatcaagaaa tggtaaacaa gttaacaaat atcagtggga actatgaaaa gtacgatggt
    68101 actttacttg ataactatat ttttcacgat acacaaaata tcagaattgg cagaagtaaa
    68161 ccgagagcgt tcattctcat caaagagaaa tatttgaatg aatggaatag cacctatgaa
    68221 atggttatga ctgataactt tgaaaaggta ttggatttca gaaatgcttt gttgggttct
    68281 gatatgggaa atagcagtct tgaatctatt gaagttgaaa acaagaccga gaatgaaggt
    68341 gaaggattga ttaagaatgt cttgaaaatc gaacaaaaat atatcagtga agatagaagt
    68401 ttttatagag tcacaagctc ggttggtcta gcaaactttg ctactaactt aattggaaac
    68461 aatgctagtg aatctttgct agtgatgtgt ctgaatacaa agaatgaggt cattgcttat
    68521 agcgaagttt tcaaaggtgg aattaatcaa tcagtagcga taccaagaga gatttttcaa
    68581 ctagctttgc taaacaattc agcaaaaatc gcagtatcac ataatcatcc gagcggatat
    68641 gaatttccaa gtgaaaatga caaaagtttt actacgaatt tgaaaaacgc aggaaaaaca
    68701 attggtattg aattgttaga ccatatcatc gtaacaagta aaaacacaag ctattactca
    68761 tttcaagaaa atggttcttt ataaaaatta gagaaaagag gaaaacaaga tgggcgaaag
    68821 aacacaagcg ttaattacag tcaaatatgg taacagcaaa acgaaagcaa gcgtgtcgat
    68881 tcattatcag tgggggtatg gtcgatatat gctgatggac gtattgaatc aaggaattta
    68941 tttaatcaat aaagcatacg acttacgaga taaatcaaga gaagaattag caaaaggaat
    69001 ctttgataga agtacaggag ttatcaattt tgtcacctat gaatctggag tgagtgctta
    69061 tgatgaaaca gggtttggtg ggcgctatga accttatcaa gaaacgattg aagatgtgat
    69121 gaagttttca gataacaatg atggctatgc tcatttagag atggtgttcg atgaaaatgg
    69181 atttagtcta gatgataaaa ccagattgcg attgtttgat tttgagggtc aacagatagg
    69241 actaaacaag ttttgtgaaa gcggaaaaga gtttgctacg aaagatttta ttaagggata
    69301 cagattattg ctagaaaatt atggaataaa cctagaagaa gagagcgtga aataagtgtt
    69361 tgaaaaaaga aaagaccagt tccctaattt agaagcgaaa agtcaaaaag tgattgatgg
    69421 tgaaatgatt gaattattcc aaaaaagtta tggaaccata gaaactaccg caagttgcaa
    69481 atactacttt caaggaaaga gaaacacgtt taaaggcttt gccgattctg atgaagaatt
    69541 ggcaaagaaa atcattgatt ggcttgtcag cagtgaacac gtagcaagag aagataccgt
    69601 tagaacaacg attaatgggg aagtcctaac aggtactaga tgtgtttgtt gtaatcatga
    69661 atttgtagaa gatgaaggtt gctaccgaat caatgaatat ggtgatttta tttgccagag
    69721 ttgccacgag atagaatttc caaccgaaag aagttggttt gaatacatgc tacaagatta
    69781 tgagatggaa acagaaaatg gtgaagtagt tttttgtacc aaagaggaat tgagtaagag
    69841 aagcgatgat gaaattgaag attggtgtgt gtggttagta gggacagatg attgcgttgc
    69901 atattacaca acagcagaat aggagtgtga atcagcatgg aaggaatgga ttttatagat
    69961 catgaagatt tgattgattt tggttataca tggaaaggaa tggtaggtat tagcagaagt
    70021 cttgctaatg ccttttacga aagaaattat gcagtctatg tcctttatga tgacaataca
    70081 gaaagccttg ttgatgaaga gtataaattg gatttagaga atgttttata tgggatagaa
    70141 aaagaagatt tagcaaaata tattttttca tggttgggtc aataaacgaa agagggtagc
    70201 aacatgacaa aattcaaaag taaaggtatg caatggtgtt cttattatta tgttgggaat
    70261 gatgaagagc ttttgagaaa agccaaacaa aaaggttatc cagataagat gttaaaacag
    70321 attggctatt acatgccaga agagagaata gaaaaagaat cttgtaaggt tctttttgat
    70381 agtgaacagc tattagtttt gttaactcaa aataaattga tttgtcaatt tgaaaataat
    70441 taatatgggg tgaagaacca tgaatgagaa taagatggta ttaagtgaat acgcaagatt
    70501 gagaaccatt aattggttga atggtatgca aagtagtggc gcttttgatg gatttgatga
    70561 ggagaatatg gactttgaaa gtttatcgaa tgaggatatt agatattatt ttatcgaatg
    70621 gtattttaca gaaccagatg aagaggtgga agatgaacca gaattaattt tagaacgtca
    70681 aagaatttta ttcagtgaac aagatagtaa gaggttgtat ggtttatatg acttacaact
    70741 gaaaggatta aaagcgcagt atgttgctga tagttacgat gatatggtag aacagggggc
    70801 agatagggtt gtcacttatt cagaagatga tgaagaggaa tgggaaaact attcagatga
    70861 tgagatatgc tttaatgatg ggtatatgcc tattgaaatc accgaagaag aatatgataa
    70921 agtgtcggat agcgatgaga ttggtatgtg tacggttgta agtggattgg atatagatgt
    70981 ccaaagagta gaggttgcat accagaagat gaaagaacgt ataaaaagta aagtagaatc
    71041 ttgatttgat tggattgttt gcaaagtagc taattaagag tataatataa tcataaatgt
    71101 agttaatgga tataataatg agtatattat actcaaaaga ggtgaacgaa atgaaggtaa
    71161 aaaatccaaa agaaaaaagc agaattcaag tcggaataga caaggattta aaagaaaacg
    71221 cagaaatgat attggaagag ctagggttaa atccaacaac agcaatcaca atcctttata
    71281 agcaagtggt cgctagaggt gagtttccag tagagataaa gctaagcgaa gaggaaaagc
    71341 aaggaatcag attgcaacag ctaactatgg atatgccagt tgatgttcta gatacagatg
    71401 aaaagttaga agagtggttc aatgaagcct aatgagatag taacggtcta tgttgcattt
    71461 acagataaaa atggtggtaa aagaagacct attttggtgg ttagtgataa agaagataga
    71521 gtagaatttt ttggaatcac aagtcaatat gagaataaat cagaccaaat aaagagagtg
    71581 tattttccta ttgcagaatg ggaaaaagta ggtctaaaga agcaatcatg gattgacgta
    71641 gggtctttaa aggctattcc caaaagccga gagaacatat catttaaaaa ggttggtatg
    71701 ctatcagcta ttgatacgaa aaagctaaat aggtttatcg agagattaca aagaaaagtc
    71761 taacaaggct tttctttttt tgtttatatg tatattaaga tatacgttta tataaacgta
    71821 tttatgtata ttaaaataca cgtaaatata tacgtgatta taaaaattaa gaaaatatta
    71881 agtattgtta aatagtgata attagtaata tacgaattat aagatacatt ttatatttaa
    71941 tgtatgtaaa taaataaaat gactgacgga tattgaatag taataaataa caataattca
    72001 gacggataca gtgagtgaag tagcttgcta cgaacgaaca ggcagaatga aacggtagtt
    72061 tcattagagc aagtcgcttg cgacgtagcg ttaccactga tgtaactggc aagttacata
    72121 gagagagttt gcttgcaaac gaacgttacc cacttgaata gaaaacaaaa ataacatatt
    72181 agtgaatttt gaataggagc cacaactcaa ccaaccgctt gcggtgggtg agtcccacgg
    72241 aggaaaagac gaacgaacgg tcgcgtagc
//
LOCUS       DAZKPE010000006        69975 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000006 DAZKPE010000000
VERSION     DAZKPE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.006"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            152..670
                     /locus_tag="ACG930_000435"
     CDS             152..670
                     /locus_tag="ACG930_000435"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0517625.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            798..1481
                     /locus_tag="ACG930_000436"
     CDS             798..1481
                     /locus_tag="ACG930_000436"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFQ0517626.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1790..1863
                     /locus_tag="ACG930_000437"
     tRNA            1790..1863
                     /locus_tag="ACG930_000437"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1824..1826,aa:Arg,seq:tct)
     gene            2022..2381
                     /locus_tag="ACG930_000438"
     CDS             2022..2381
                     /locus_tag="ACG930_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFQ0517627.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2504..4135
                     /locus_tag="ACG930_000439"
     CDS             2504..4135
                     /locus_tag="ACG930_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFQ0517628.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4197..4838)
                     /locus_tag="ACG930_000440"
     CDS             complement(4197..4838)
                     /locus_tag="ACG930_000440"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFQ0517629.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5024..5100
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5120..5428
                     /gene="rplU"
                     /locus_tag="ACG930_000441"
     CDS             5120..5428
                     /gene="rplU"
                     /locus_tag="ACG930_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFQ0517630.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5455..5799
                     /locus_tag="ACG930_000442"
     CDS             5455..5799
                     /locus_tag="ACG930_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFQ0517631.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5812..6105
                     /gene="rpmA"
                     /locus_tag="ACG930_000443"
     CDS             5812..6105
                     /gene="rpmA"
                     /locus_tag="ACG930_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFQ0517632.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6539..9346
                     /locus_tag="ACG930_000444"
     CDS             6539..9346
                     /locus_tag="ACG930_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0517633.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9537..10028
                     /locus_tag="ACG930_000445"
     CDS             9537..10028
                     /locus_tag="ACG930_000445"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFQ0517634.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10131..11120
                     /locus_tag="ACG930_000446"
     CDS             10131..11120
                     /locus_tag="ACG930_000446"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFQ0517635.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11153..11956
                     /locus_tag="ACG930_000447"
     CDS             11153..11956
                     /locus_tag="ACG930_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFQ0517636.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11977..12891
                     /locus_tag="ACG930_000448"
     CDS             11977..12891
                     /locus_tag="ACG930_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0517637.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12974..13348
                     /locus_tag="ACG930_000449"
     CDS             12974..13348
                     /locus_tag="ACG930_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFQ0517638.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13487..13732
                     /locus_tag="ACG930_000450"
     CDS             13487..13732
                     /locus_tag="ACG930_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0517639.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13904..14968
                     /locus_tag="ACG930_000451"
     CDS             13904..14968
                     /locus_tag="ACG930_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFQ0517640.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15214..15639
                     /locus_tag="ACG930_000452"
     CDS             15214..15639
                     /locus_tag="ACG930_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0517641.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15632..16081
                     /gene="nusB"
                     /locus_tag="ACG930_000453"
     CDS             15632..16081
                     /gene="nusB"
                     /locus_tag="ACG930_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFQ0517642.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16178..17032
                     /locus_tag="ACG930_000454"
     CDS             16178..17032
                     /locus_tag="ACG930_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFQ0517643.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17033..18370
                     /gene="xseA"
                     /locus_tag="ACG930_000455"
     CDS             17033..18370
                     /gene="xseA"
                     /locus_tag="ACG930_000455"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFQ0517644.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18375..18599
                     /locus_tag="ACG930_000456"
     CDS             18375..18599
                     /locus_tag="ACG930_000456"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFQ0517645.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18601..19491
                     /locus_tag="ACG930_000457"
     CDS             18601..19491
                     /locus_tag="ACG930_000457"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFQ0517646.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19500..20318
                     /locus_tag="ACG930_000458"
     CDS             19500..20318
                     /locus_tag="ACG930_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFQ0517647.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20425..20874
                     /locus_tag="ACG930_000459"
     CDS             20425..20874
                     /locus_tag="ACG930_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0517648.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20892..22574
                     /gene="recN"
                     /locus_tag="ACG930_000460"
     CDS             20892..22574
                     /gene="recN"
                     /locus_tag="ACG930_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFQ0517649.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22629..22745)
                     /locus_tag="ACG930_000461"
     CDS             complement(22629..22745)
                     /locus_tag="ACG930_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFQ0517650.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22818..23774)
                     /locus_tag="ACG930_000462"
     CDS             complement(22818..23774)
                     /locus_tag="ACG930_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0517651.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23945..24313
                     /locus_tag="ACG930_000463"
     CDS             23945..24313
                     /locus_tag="ACG930_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFQ0517652.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24483..24914
                     /gene="mraZ"
                     /locus_tag="ACG930_000464"
     CDS             24483..24914
                     /gene="mraZ"
                     /locus_tag="ACG930_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFQ0517653.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24935..25894
                     /gene="rsmH"
                     /locus_tag="ACG930_000465"
     CDS             24935..25894
                     /gene="rsmH"
                     /locus_tag="ACG930_000465"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFQ0517654.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25899..26300
                     /gene="ftsL"
                     /locus_tag="ACG930_000466"
     CDS             25899..26300
                     /gene="ftsL"
                     /locus_tag="ACG930_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFQ0517655.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26301..28493
                     /locus_tag="ACG930_000467"
     CDS             26301..28493
                     /locus_tag="ACG930_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFQ0517656.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEENGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28519..29481
                     /gene="mraY"
                     /locus_tag="ACG930_000468"
     CDS             28519..29481
                     /gene="mraY"
                     /locus_tag="ACG930_000468"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFQ0517657.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29495..30856
                     /gene="murD"
                     /locus_tag="ACG930_000469"
     CDS             29495..30856
                     /gene="murD"
                     /locus_tag="ACG930_000469"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFQ0517658.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30882..31970
                     /gene="murG"
                     /locus_tag="ACG930_000470"
     CDS             30882..31970
                     /gene="murG"
                     /locus_tag="ACG930_000470"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFQ0517659.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31985..33205
                     /locus_tag="ACG930_000471"
     CDS             31985..33205
                     /locus_tag="ACG930_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFQ0517660.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33361..34686
                     /gene="ftsA"
                     /locus_tag="ACG930_000472"
     CDS             33361..34686
                     /gene="ftsA"
                     /locus_tag="ACG930_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFQ0517661.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34709..35950
                     /gene="ftsZ"
                     /locus_tag="ACG930_000473"
     CDS             34709..35950
                     /gene="ftsZ"
                     /locus_tag="ACG930_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFQ0517662.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35967..36644
                     /locus_tag="ACG930_000474"
     CDS             35967..36644
                     /locus_tag="ACG930_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFQ0517663.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36658..37257
                     /locus_tag="ACG930_000475"
     CDS             36658..37257
                     /locus_tag="ACG930_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFQ0517664.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37338..37559
                     /locus_tag="ACG930_000476"
     CDS             37338..37559
                     /locus_tag="ACG930_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFQ0517665.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37608..38390
                     /locus_tag="ACG930_000477"
     CDS             37608..38390
                     /locus_tag="ACG930_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFQ0517666.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38411..39118
                     /locus_tag="ACG930_000478"
     CDS             38411..39118
                     /locus_tag="ACG930_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFQ0517667.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39380..42178
                     /gene="ileS"
                     /locus_tag="ACG930_000479"
     CDS             39380..42178
                     /gene="ileS"
                     /locus_tag="ACG930_000479"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFQ0517668.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42227..43753)
                     /gene="zwf"
                     /locus_tag="ACG930_000480"
     CDS             complement(42227..43753)
                     /gene="zwf"
                     /locus_tag="ACG930_000480"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFQ0517669.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43768..44415)
                     /locus_tag="ACG930_000481"
     CDS             complement(43768..44415)
                     /locus_tag="ACG930_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFQ0517670.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44599..44928)
                     /locus_tag="ACG930_000482"
     CDS             complement(44599..44928)
                     /locus_tag="ACG930_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFQ0517671.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45105..45833
                     /gene="sfsA"
                     /locus_tag="ACG930_000483"
     CDS             45105..45833
                     /gene="sfsA"
                     /locus_tag="ACG930_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFQ0517672.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45849..46862
                     /locus_tag="ACG930_000484"
     CDS             45849..46862
                     /locus_tag="ACG930_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0517673.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46862..48139
                     /locus_tag="ACG930_000485"
     CDS             46862..48139
                     /locus_tag="ACG930_000485"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0517674.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48202..50904
                     /locus_tag="ACG930_000486"
     CDS             48202..50904
                     /locus_tag="ACG930_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0517675.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51056..51373
                     /locus_tag="ACG930_000487"
     CDS             51056..51373
                     /locus_tag="ACG930_000487"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0517676.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51403..51723
                     /locus_tag="ACG930_000488"
     CDS             51403..51723
                     /locus_tag="ACG930_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0517677.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51831..53291
                     /locus_tag="ACG930_000489"
     CDS             51831..53291
                     /locus_tag="ACG930_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0517678.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53359..53580
                     /locus_tag="ACG930_000490"
     CDS             53359..53580
                     /locus_tag="ACG930_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517679.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53611..53793
                     /locus_tag="ACG930_000491"
     CDS             53611..53793
                     /locus_tag="ACG930_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFQ0517680.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53793..54206
                     /locus_tag="ACG930_000492"
     CDS             53793..54206
                     /locus_tag="ACG930_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFQ0517681.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54329..55510
                     /locus_tag="ACG930_000493"
     CDS             54329..55510
                     /locus_tag="ACG930_000493"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0517682.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55581..55745)
                     /locus_tag="ACG930_000494"
     CDS             complement(55581..55745)
                     /locus_tag="ACG930_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517683.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55899..55972
                     /locus_tag="ACG930_000495"
     tRNA            55899..55972
                     /locus_tag="ACG930_000495"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55933..55935,aa:Arg,seq:cct)
     gene            complement(56041..57180)
                     /locus_tag="ACG930_000496"
     CDS             complement(56041..57180)
                     /locus_tag="ACG930_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0517684.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57294..57878)
                     /locus_tag="ACG930_000497"
     CDS             complement(57294..57878)
                     /locus_tag="ACG930_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFQ0517685.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(57961..58383)
                     /locus_tag="ACG930_000498"
     CDS             complement(57961..58383)
                     /locus_tag="ACG930_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0517686.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADKIAIMILLNIFIENELTDE
                     SQFKLENFMEFYAINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(58401..58721)
                     /locus_tag="ACG930_000499"
     CDS             complement(58401..58721)
                     /locus_tag="ACG930_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517687.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            59021..59161
                     /locus_tag="ACG930_000500"
     CDS             59021..59161
                     /locus_tag="ACG930_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517688.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            59459..59716
                     /locus_tag="ACG930_000501"
     CDS             59459..59716
                     /locus_tag="ACG930_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HFQ0517689.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(59687..59995)
                     /locus_tag="ACG930_000502"
     CDS             complement(59687..59995)
                     /locus_tag="ACG930_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517690.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            60073..60819
                     /locus_tag="ACG930_000503"
     CDS             60073..60819
                     /locus_tag="ACG930_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFQ0517691.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            60834..61037
                     /locus_tag="ACG930_000504"
     CDS             60834..61037
                     /locus_tag="ACG930_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517692.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61053..61391
                     /locus_tag="ACG930_000505"
     CDS             61053..61391
                     /locus_tag="ACG930_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFQ0517693.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61378..61548
                     /locus_tag="ACG930_000506"
     CDS             61378..61548
                     /locus_tag="ACG930_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517694.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(61646..62311)
                     /locus_tag="ACG930_000507"
     CDS             complement(61646..62311)
                     /locus_tag="ACG930_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517695.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            62366..63064
                     /locus_tag="ACG930_000508"
     CDS             62366..63064
                     /locus_tag="ACG930_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFQ0517696.1"
                     /translation="MQELVILKNKEAVTTSLQVADSFEKEHKNVLRDIEKLKEDVLNF
                     EQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            63242..63583
                     /locus_tag="ACG930_000509"
     CDS             63242..63583
                     /locus_tag="ACG930_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517697.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            63576..64247
                     /locus_tag="ACG930_000510"
     CDS             63576..64247
                     /locus_tag="ACG930_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFQ0517698.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVTPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64253..64939
                     /locus_tag="ACG930_000511"
     CDS             64253..64939
                     /locus_tag="ACG930_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFQ0517699.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIERLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            64942..65691
                     /locus_tag="ACG930_000512"
     CDS             64942..65691
                     /locus_tag="ACG930_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517700.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            65703..65972
                     /locus_tag="ACG930_000513"
     CDS             65703..65972
                     /locus_tag="ACG930_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517701.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            65977..66141
                     /locus_tag="ACG930_000514"
     CDS             65977..66141
                     /locus_tag="ACG930_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517702.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            66134..66436
                     /locus_tag="ACG930_000515"
     CDS             66134..66436
                     /locus_tag="ACG930_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517703.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            66433..66594
                     /locus_tag="ACG930_000516"
     CDS             66433..66594
                     /locus_tag="ACG930_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0517704.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            66591..66896
                     /locus_tag="ACG930_000517"
     CDS             66591..66896
                     /locus_tag="ACG930_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517705.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            66896..67252
                     /locus_tag="ACG930_000518"
     CDS             66896..67252
                     /locus_tag="ACG930_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFQ0517706.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            67212..67457
                     /locus_tag="ACG930_000519"
     CDS             67212..67457
                     /locus_tag="ACG930_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517707.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            67454..67873
                     /locus_tag="ACG930_000520"
     CDS             67454..67873
                     /locus_tag="ACG930_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFQ0517708.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            67870..68427
                     /locus_tag="ACG930_000521"
     CDS             67870..68427
                     /locus_tag="ACG930_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFQ0517709.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            68424..68720
                     /locus_tag="ACG930_000522"
     CDS             68424..68720
                     /locus_tag="ACG930_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517710.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            68797..69210
                     /locus_tag="ACG930_000523"
     CDS             68797..69210
                     /locus_tag="ACG930_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFQ0517711.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            69519..69671
                     /locus_tag="ACG930_000524"
     CDS             69519..69671
                     /locus_tag="ACG930_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517712.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(69668..69943)
                     /locus_tag="ACG930_000525"
     CDS             complement(69668..69943)
                     /locus_tag="ACG930_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517713.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
BASE COUNT        23496 a        11671 c        14769 g        20039 t
ORIGIN      
        1 attatttata ataaaaaatg agataaagat gaggaaatag aattagaaac atataattat
       61 taaagggaaa catttttaca gctataattt gaaaaaattt atcgttatta tatgattaag
      121 aaggattgaa taaagaaaga agttgaaaac gatacctgat tacaaaaaaa taacttttat
      181 aagttctata acgttgatta tatttttaat tcttattctt ctcgtcgtct tggttccccg
      241 aatttttggt ttgactcctt atattattga ggacaaagaa atgagtccat attatgcaca
      301 aggaaatctg atatatgtac gaccgaaaaa tacaaatgag attttagtcg gagatattat
      361 tacatattat gaaaattcag gaaaaaaaat ctcgacgcgt cgcgtaatag ccgttgaaaa
      421 caaccacgaa gatttttata caaaagctga tacaaagact tatattgagc ctggagtagt
      481 aaaaaagaga aatattatcg gtagtcccat ctttcagatt ccatatattg gactagtcct
      541 ttcaaaaacg gcatttgcat ggattcaggg gttattcttt acgattgctt tttgcctaac
      601 aggaatcaca gcatggaata cctttgtaga gttgaaaaag aagcggagac gaacacagaa
      661 atttttgtaa gaatgttaaa aacataaatg tattccagag atccaacgac tcttctgaac
      721 atgaaacacg agaaaacact catgcagctt gtagatttag tcagttgttc gtataatgtg
      781 tgaagaggag gagtagtatg cgcaatgaaa tgatgcatcg tcctgtagtc aaagaagaac
      841 tattggattt tatgcgtacc cagcaaaaaa aattaccggg tgagctaggc aaactggaag
      901 aagaagctca tgtagcagaa gtaccagtta ttccccatga aacagttgta tttttgaaat
      961 ttttacttgg acagcttcag cctgaacgaa tcttggagat cggagcagct atcggttttt
     1021 catcaagtgt catggccacg acaatcggag aaaacgctca tgttacgaca attgatcgtt
     1081 tcgatgtcat gatcgagaaa gctaaaaaaa actatgaacg tctaggactg acagataaag
     1141 tgactttgct tgaaggtcaa gcagcagata tcttgccgga gttgtctggt ccgtatgact
     1201 ttatttttat ggatagtgca aaatcaaaat atattgaatt tttacctgaa tgcttacgtt
     1261 tgttaagaaa aggtggcgtt ttgatggtag atgacatctt ccaaggagga acgatcttgc
     1321 tcccagatga agagattccc cgtggcaaac gagctatcca tcgtaaatta aatgaatttc
     1381 ttcgtgttgt gatggatcat cccgatttga catcgacaat cttgccatta ggtgatggtg
     1441 tgatcttaat gacaaaggaa tcagaaacaa tcgagttgtg atacatgatt atggcagcct
     1501 gtagataatc gattgaatcg agggctcaat tcgaacttga tgtaaaagtt tctatatttg
     1561 taagtcaatt aaaggataca ggaaatctaa ataaacagga gtagcatgaa gtcaatgtag
     1621 ctcctgtttt caattgataa ccttagaaca gctgaaggag aatgtctcgt tttaaaagat
     1681 tgatttagta gttgggccaa aataattcat tatttgctaa ttaaataact atttcgtatt
     1741 gacagaagca atttaattat ctataattat tgatgttccg ctgattcttg tcatagtagc
     1801 tcagctggat agagcatccg ccttctaagc ggacggtcgg gggttcgaat ccctcctgtg
     1861 acgctaaaaa accgttagaa actgaggttt ctaacggttt ttctttgttt tttgtgccaa
     1921 tattgtttgt tttcaaaggc aaataaaata aaaaaacatc cttatcgagt acaattataa
     1981 ggagcaaaaa aataaaactc atcagaaaag aggaagaaga tatgacgata ctatctagaa
     2041 ttttagtgac tctagttgca attgaatttt tttatatcat gtatatcgaa acggtgagaa
     2101 ctgattctga cacgacaagt agggttttta aaatgagtaa agaagagtta agcagaaaat
     2161 ctgttcaaac attgtttaag aaccaaggag tgtacaatgg actattagga gtgggactac
     2221 tttatggagc ttatctttct tccgcatcta aagaaatcac aagtatgcta ttaatatcta
     2281 ttttttttgt tgcattatat ggcagtttga ctagcgatcg ttggatttta ctcaaacaag
     2341 gtgggctagc tctgttggca ttgctttcta ttttcttata aatatagaaa aaataagaat
     2401 ttatctaaca ggaaactttg tgaaaaatat tactttatct catgaaatat gatattctaa
     2461 tgaatggtat tttagaaaat ttcatgaaaa aggagttaga taggtgttca aaaattatgt
     2521 ttcctcacta aaaaaagaat tttcaggtta tgatctttca agatttcaga aagatctttt
     2581 ggctgggatc acagtagctg ctgtagcatt gcctttagcc ttggcttttg gggtatcaag
     2641 cggagctgat gcggccgcag gtttgattac ggctatcatt gccggtatcg ttattggcgg
     2701 tttatcaggc ggtttttatc aaatatcagg tccgacaggt gcgatggcag ctatcttgat
     2761 gtctattgcg gcaacaaagg gaatgcaagg tgtattgctt gctacttttt tagcgggtct
     2821 atttttactt gcagcaggac ttttccgatt aggaacactg acttctttta tcccagcacc
     2881 cgtaattacg gggtttactt caggtattgc tatcattatt gcattaggtc agatcgataa
     2941 tttatttggt gttcactcgg aaggtacaaa cgttattgaa aaactaagta gttatcaaac
     3001 gataggattt ccgataaaca cagcctcttt gatcatggga gggctagtca ttttagggat
     3061 gtttatctat ccaaaaaaat gggcgaaacg aatgcctagt tcgctgctgg ctatcatttt
     3121 ggcaacagca gttatgctat tgttccattt accagtagca actgtgggta agattccaca
     3181 aacattgatc agtagtaatc gtttgaatat gggagatttt agcttttctg ccttgcaaca
     3241 agtggcagtt ccagctatta gcattgcttt attaggaatg attgaaagct tgctatgtgg
     3301 tgcttcggct ggccgaatgg caaataagcc cttagatagc aatcaagaat taatggcgca
     3361 aggaattgga aatctgttgc ttcctttctt tggcgggatt cctgctactg cggccatcgc
     3421 ccgtacaagc gtggccatca aatctggtgc acaaactaga ttagctggta tgatacatgc
     3481 agttgtctta ctgctctcca tgcttgtttt tgcgccagtg atgtcacaga ttccaatgcc
     3541 agcacttgca ggtgttttga ttgtgacggc ttggcgtatg aatgaatggg aaacgatcaa
     3601 ggagctattt actaataaat attggtcagc agttctattg tttatcctta cgatgatttg
     3661 tacagttatc tttgatttaa gtattgctat cgtgatcggg gtgatcggcg gctgtgtatt
     3721 ttttgttgtc aaaagcgctg ctatcacgat ttcattagaa acgatcgatt ggcaaagaat
     3781 ggggctgcca gaaacggaaa agctgaataa ctggacagta gtgtatatta gtggtccact
     3841 gttttttatg tcttcagaaa aactcaaaaa taaattggaa gaactaaatc atcacgatgg
     3901 tgtcattttc tccatgcgag gcgtaccaag tattgatttg acggcacgtg cagtttttga
     3961 tgaatttcaa gaaaaagcag agcaaagagg acaaacgatt atctatactt ccttgcagcc
     4021 agaagtagaa aaacaacttt ctcacttgtg ggaacataca ttcacgcatc aacatcaaac
     4081 agttgctcat gcgttgacag ctttacatgc gaaatatact gcaattagcc attaaaacaa
     4141 tgaaaaagaa cagacaagac tgtaaactga agattttatg gtcttgtctg ttctttttaa
     4201 tattgctgta aaagtgaagc tagtacttgc cagtcttgat ggataacagg tacaagggag
     4261 cgattgtaga aaatagctgc tggatgaaaa agtggaagaa ttcgatagtt tttttctgac
     4321 cattcgtagg catccttttg ttctgttaat tgtaagacag gccctgtata gagttgacca
     4381 tgatttttgg taaccgtata ttctttgcca agtaaacgtt gaagaccaat gtttccaagt
     4441 gtcgcaatta attttggctg gaccttcatc agttcgtaat ccaatattgg tgcatgcgca
     4501 aatacttcgg aacgagtagg tgtccgattt ggataaacag tttctgactg ttgtgtccgt
     4561 ttattgatcc gatgagtcac gcgatacggg cggctcctta cagcactggt gatatacacc
     4621 tcttctcgtg ttaagccagt tgaagaaagt gcctgcatca attcttttcc agcttgaccg
     4681 ctaaaaggaa catgcgtatc aatctctgtt ttccctgggg cttctcccac gagcatcagt
     4741 ttaggatgaa gaggtccttg cccagcgata aatccttcta caggacggcc gttcattctt
     4801 aaagaagctt cttgtatcag ttcttttggg tattccattt atgctcctcc tttttctttt
     4861 attataagaa taaaagaaac acaatgcgac tattttattt ggtagaactg tgaggataga
     4921 aaagcagaag tattgcttga atttttgttt tactttttga ttttaaattt agttgactaa
     4981 cggttgctgt tctggtaagc tagtactgtt gtaattgtgg actccacagc tacaaccgct
     5041 cagaacaagt aataagcaca gcatatgctg tcacttcgga tggcgagtct aagtatatca
     5101 gaaggaggtg ctttatagca tgtacgcaat tattaaaact ggtggtaaac aagtaaaagt
     5161 tgaagtggga caagcaatct atgttgaaaa acttgacgtt gaagcaggag aaaaagttgt
     5221 ttttgacgaa gttatcttag taggcggaga atctacaaaa gtaggcgctc caactgttgc
     5281 aggtgcaact gttgaaggta ctgttgaaaa acacggcaaa caaaagaaag tcgttacttt
     5341 caaatacaaa cctaaaaaac attcacaccg taaacaaggt catcgtcaac catatacaaa
     5401 agtggttatc gacgcgatca acgcttaata gcgtttgaga aagaaggcct atatatgatc
     5461 aaaggaacat ttaagcgaaa tgacgcaggt cagatcgttt cattcacttt gaccgggcat
     5521 gctgatgctg gtccttatgg aagtgatatc gtttgtgcgg gtgtttctgc gttagcgatc
     5581 agcactgtca acgggattgc ctcattagcc ggttttgagc cgattgttga aatgaatgaa
     5641 gaagaaggcg gttatcttta taccgaagtc acttcaggaa tgacacaaga acaaaacaat
     5701 attgctgaga ttctattaga aaatctttta ttaggattac aatcgataga agctgaaaac
     5761 tcagaatata tccaaattaa aacaattaat gataaatagg aggtgcagac catgttgtta
     5821 tctatgaatc tacaattatt tgcccacaaa aaaggtggcg gttctacatc taacggccgt
     5881 gactcagaat caaaacgtct aggtgctaaa cgtgctgatg gacaaacagt tacaggtgga
     5941 tcaattcttt accgtcaacg cggtacaaaa atctatccag gtgtaaacgt gggtatcggt
     6001 ggagacgaca ctttatttgc aaaagttgat ggcgtagtac gtttcgaacg taaaggccgt
     6061 aacaaaaaac aagtgtctgt ttatccagta gctcaagaag cttaattgaa tcttatgatt
     6121 aaagaggttg tgacaagact tttgtcacag ccttttttgt ttataaaaat aaaagttgta
     6181 gtggaggcta cgaagtttac tttgtctttt tacacttaat atttttttgc caatttggaa
     6241 tcaggatgtt ttgataacta tcgttttcaa ttgatggaag ctatattgtt tgctatcagt
     6301 gaaataatta tatggtaaac agtgttcttt ttcttgtttc cattataaaa atcgtatcgg
     6361 gatttttcgt tcttttaaat tgaacatttc tatctatccg cgtgttatca acaaaacaaa
     6421 atcaggtaaa tagttgacga aacagaaata aatacatagt attatgtttt gaagcctaag
     6481 tacaatagtc tatagaaaag gagcgatacc attggcaaaa cgcattgacc gaatttatat
     6541 gtatgtcaaa gaaaaaaccg ctcatttaac aaaggcagaa tatgatcaag gagtaacaac
     6601 acaggaaatt gctgaagtgt tagggattca gcgaacaaat agcagtaaag atctgaatca
     6661 gctagtgcgc gaaggaaaac tgataaagac agacggacga ccagtacgtt acatatatca
     6721 aacactcgtt acgcacgtaa agccagttac aaaacatgta gtcagttaca aagaaacgcc
     6781 ggtctctgaa gaaaaaaata cactccaaat agatactaag gatatctttg caaaaatcat
     6841 tggagctaac ggcagcatga aaaattcagt ggaacaggca aaagctgcga ttttgtatcc
     6901 gccaagagga ttaaattgtt tgattacagg acctaccgga tcaggaaaga cttattttgc
     6961 acacgcgatg tatcattttg caaaagcgca tcatgtaata gatgaggaaa cggaactgat
     7021 tgttttcaat tgtgctgatt atgccaataa ccctgagctt ttgatgagtc atttatttgg
     7081 gtacgcaaaa ggtgctttta caggcgcaga tgaagaaaaa atggggatta tcgatcaagc
     7141 ggatggcggt atgctgtttt tggatgagat tcaccggttg ccgcctgaag gtcaagaaat
     7201 gatcttttac tttatggatc atggaactta cagtcgtctt ggggaaacaa cgaaatccca
     7261 tgaagcaaat gtacggatcg taggtgcgac cacagaagac ccaggttctt ctctattaga
     7321 aacttttgtt cggcgtatcc caatcaatat caaacttccg gcttttgaaa aacgtcctgc
     7381 aaatgagaaa gtcgatttag taaaaatcat gattgcccac gaagcaaacc gcacgcagcg
     7441 aaagatttct ttgacagaag atgtagcaaa agcattgatc ggcagtgtga cctatggaaa
     7501 tataggacaa ttgaagtcaa atatccagtt agtatgtgca cgaggatttc taaatcatat
     7561 gcaatcaccc gaaatctcga tcacaatcga tgatttgaca gaagggattc gtagcggatt
     7621 gattcaatta gcaagcaacc gcagtgcaat ggcagagctt tctaaaatat tggagccaaa
     7681 gataactgta gcaccaaatg atacgatcat gaaaatccaa tcggactcct atgagttacc
     7741 ttataatcta tatgatatca tcggagataa agcagcttta ctgaagtcgg atggtttgga
     7801 tcaagaagca atcaatcatt tcatttctac agatatcaac atccatctga agtctttcta
     7861 taaagaccat ggtttttctt ttaatgcaga cagcaaatta gcagaatttg tagatccgaa
     7921 aatcatagaa gtgaccaatc agatttatgt aatggtcaaa agatctttac catatgagtt
     7981 tcagcaaaac tttatttatg ctatgagctt gcatatcagt tcttttttga aaaaaatcaa
     8041 cttaggagaa gaacggcata cgaatgataa catccgtgag atggcttttg attttccaga
     8101 tgaatatgct gttgcgaaag aagtgcgtag ttatatcgaa acgtattttc aagtggagat
     8161 tccagaaagt gaagactatt acttgaccgt tctactcgtc tcgttacggg caaatcaagc
     8221 aagcggcaga atcggtgtag tcgttgcagc tcacggaaac agcacagcaa gcagtatggt
     8281 ccaagttgtc caacagttgt tagatgcaga gaacgtacga gcagtagaca tgcctttgga
     8341 tatggatccg aaaacagcat tggaccgaat tgaacgcaat gtacaagaag tagatgaagg
     8401 aagcggggtc atactcttag tagatatggg gtcccttgcg tcgtttaatt cgcaaattca
     8461 aagagacact ggaattccag tacgtactgt tgatatggta acaacttctc tagttttgga
     8521 aactgtacga aaggtctcag tattagggac agatctagat atgttgcatg aatcattgaa
     8581 aaattttcga ggttacgcag aaatatcttc tgtagaatct gttcaggaag caaaacctat
     8641 tcataagaaa aaagctgttt tggctatctg cgcatctggc gaaggtacag cacaaagaat
     8701 caaagaattg atcgaacgag cggtaaacaa gcgtcaagaa acagaattag aagttctagc
     8761 tttgtcgatt gtggaagtga aagaagaact gccagttatc caaaaagaat atcagatcat
     8821 agctactact gggattactg atttgaatat ccaagcccca tttattcctt tagaacgttt
     8881 tattgatcaa aatatcgaag tcattttgga tcagttgctg atggaatcag aattggagga
     8941 aactgaattc atctccctag atgaagagtc agctaaaaat acgtgtgttg agtttatctc
     9001 tgataacttc atctttatta atggtagtaa gttaatcgat ccaatgtggc aattttctac
     9061 acaaatctct cagacgacgg gaatcggcga tgaagaatat ggattcaaaa tcaacctagt
     9121 gatgcacaca gcaggaatga tcgaacgtat tattcggaat gaaccattga ctgtggaaga
     9181 aaacgaattg acaaatacaa cgaatgatcc tctttatagc caattggcag cctcagttgt
     9241 tctgttggaa gatcagataa aagtaaaagt gccgatagaa gaaatgtatt atctgctacg
     9301 tctagtccat aatcagttag ataaaaaaga atacactgtg ccatgaatac acaaaaacga
     9361 tacactttta tagtgtatcg tttttgtgta ttggttaaga atcctttaaa ttcaattagt
     9421 gtatcgtaaa aaagttggca cgctttttgc ttatagtagt gtgtgctagg aggtggttgt
     9481 tcacacagaa atgatagggg tttctgtgaa gtagtgagga agaaggagtt ttgcagatgg
     9541 atattcgatt ggcacgtata gatgatcgtt taatccacgg gcaagtcgca acagtttggt
     9601 cgaagcaaac aggtgttgaa cgtatcattg tgatcagcga tgtagtcgct caagataaat
     9661 tgagaaagtt tctactaaaa gaagctgcac cgccggggat cacagcaaat gtaataaccg
     9721 tgcagaaaat gattcaaatc tatcatagtg gattattatc acgagcaaaa gtgatgcttt
     9781 tattcaccaa tccccaagat gttgaagcgg ttgtccgctg cggtgtacag ttgaagtcgt
     9841 tgaatatcgg cggtatgagt tttactgaag gcaaatcaat gattaccaat tttgtttcag
     9901 taaatcaaca agatattgat tcctttcgtt acttgaacag tcaagaagtg gagttagaga
     9961 ttcgaaaagt acctgctgac aggaaaatcc ttttgatgga actactagcg aaaatcaaaa
    10021 aggtgtagca agaatggttg ttggaaaagg tcaaataatt ctgttgtaat ggttagcaat
    10081 tattaatatt tttgaatttg ttacaacaaa agtaaatagg aggtataaat atggtaggga
    10141 ttatcctagc aagtcatgga caatttgctg aaggaatctt acaatccggt tcaatgatct
    10201 ttggcgaaca agaaaacgtc aaagccgtga ttttgaaacc aagtgaaggt ccagatgact
    10261 tgagagccaa attggaagaa gcggttgctt cttttgataa tcaagacgaa gtgttattct
    10321 tagttgattt atggggcgga acaccgttca atcaatcaaa cacattattc gaagagcaca
    10381 aagataaatg ggcaatcgtc agcggtttga atttaccaat gttgattgaa gcctacgcat
    10441 cacgcttttc aatggaatct gctcatgaaa ttgcagcaca catcattgaa acagcaaaag
    10501 acggtgtaaa agtaaaaccg gaagaattag aaccggcaga agcaccgaaa gcagcagttg
    10561 aagacgcaca acctaaagga gcacttccag aaggaactgt ggtcggagac ggaaaaatca
    10621 aatatgtatt agcacgtgtt gactcacgtc tgttacatgg acaagttgcg acagcttgga
    10681 caaaagcagt gcaaccaaac cgtattatcg ttgtttcaga tgcagtatca aaggatgatc
    10741 tgcgtaagag actaatcgaa caagctgctc ctccaggtgt aaaagcaaat gttattccta
    10801 ttagcaaaat gatcgaagta gcaaaagacc ctcgttttgg aaataccaaa gcattgcttt
    10861 tatttgaaaa tcctgaagac gtattgacag ctgttgaagg tggcgtagac atcaaagaat
    10921 taaatgttgg gtcaatggcg cattcggtcg gtaaagtcgt tgtaagtaaa gtattgtcta
    10981 tgggacaaga agacgttgaa gcgtttgaga agcttgaaca aaaaggtgtg aaattcgatg
    11041 tacgtaaagt acctaatgat tcacgcgata acatggatga tattttgaaa aaagcaaaag
    11101 ctgaattagc aaaagcgtaa taaataatat taaaatttat aggaggctta tcatgtctat
    11161 tatttcaata attttagtcg tattagttgc ctttctagct ggtatggaag gtattcttga
    11221 tgaatttcaa tttcatcaac cactagtggc atgtacattg atcggtttag ttaccggtaa
    11281 cctcgaagct ggtatcgtac ttggcggtac gcttcagatg atcgctttag gttgggcaaa
    11341 tatcggtgcc gctgtagcac cagatgctgc attagcatca gtagcatcag caattatttt
    11401 agttttaggt ggacaaggtg ttaaaggtgt tccttctgcg atcgcgattg ccgttccttt
    11461 ggctgttgca gggttgttct taacaatgat cgtacgtaca atcgctgttc caatcgttca
    11521 tttgatggat gcggctgctg aagaaggaaa catccgtaag gttgaaatgt ggcacatcat
    11581 tgctgtatgt ttacaagggg ttcgtatcgc ggtcccagca gcagcgttgc tatttatccc
    11641 agcacaaact gtgcaatcat tccttgaatc aatgccagca tggttaacag atggtatggc
    11701 tatcggtggg ggaatggtcg tagctgtagg ttacgctttg gtaatcaaca tgatggctac
    11761 aaaagaagta tggccattct tcgttattgg tttcgttgta gctgcaattt ctcaattaac
    11821 attgattgct ctaggtgctt taggtgttgc attagctctt atttacttga acctttctaa
    11881 aatgggtggt tcatcaaata atggaggcgg aagcaactct ggtgaccctt taggcgacat
    11941 tttgaatgac tattaatctt gaaggaggaa aataaaatgg cagaagaaaa aatcaaatta
    12001 tcaaaaaaag atcgtttagc tgttgcgtgg cgctctacct tcattcaagg ttcatggaac
    12061 tacgaacgta tgcaaaacgg tggctgggca ttttctatga ttccagcaat caaaaaatta
    12121 tacaaaacaa aagaagaacg ttctgcagca ttaaaacgtc acttggaatt ctttaataca
    12181 cacccataca ttgcttctcc aattttaggg gttacattgg ctctggaaga agaacgtgcg
    12241 aatggcgcgc ctgttgatga tgtagcgatt caaggggtta aagtaggtat gatgggtcct
    12301 ttagctggtg ttggtgaccc agtgttctgg tttacagtac gtccaatgct aggtgcacta
    12361 ggtgcttcat tagctatggg aggaaatatc cttggaccaa tcatcttctt cttaggttgg
    12421 aacattattc gttgggcatt catgtggtat acacaagaat ttggctacaa agctggttct
    12481 aaaattactg atgacctttc tggcggattg ttacaagacg taacaaaagg tgcttcaatt
    12541 ttagggatgt tcgtattagc tgcccttgta caaagatggg tatcaatcaa attcttacca
    12601 gttgtatcaa ctgtaaaatt agataaaggt gcttacatcg aatgggataa attgccttca
    12661 ggtggtgaag gaatcaagag tgcatttgaa caagttaata atggcttagc cctttctcct
    12721 gaaaaggtaa caacattaca agacaactta gaccaattga ttcctggttt agctgcatta
    12781 ggattaacat tgttatgtat gtggttgctt aagaaaaagg tttctccaat cgttatcatc
    12841 cttggtttat tcgtagtcgg tgttgttgga cacgtcatcg gacttttata atccataaaa
    12901 atatagctcg ggcgttgtcc cgagcttttt ttatatagta tactgttcat aaacaaatat
    12961 ctggagggag aaaatggttc aatcaatcaa tacaaaagta gacttggtaa ttgatgctac
    13021 ttcgtttacg ggtctgacag attacgggca aatcatgata ggtaataatg gttttgagtt
    13081 ttaccatgcg cgagatagac gcaaatatat ccaaattcca tgggaagaag tggattatgt
    13141 actagcatca gtcatgctaa agggaaaatg gattcctcga tatgccattc aaacgaaaaa
    13201 aaatggtaca tacacatttt cttccaaaga acctaaaaaa gtgcttcgtg cgatcagaga
    13261 atatgtagat gaagatagaa tggtacaatc attgagtttc tttgatgtag tgaaacgtgg
    13321 tattcgtagt atgtttaaac gcaagtaaaa aataaagaaa acttctaaga ggaggttttc
    13381 tttatttttt tactttgcag aagaaaatat gaaatagcaa aaccaattat ttgtcccctt
    13441 taaatcccat atgctaaaat tgattagcaa agaaggaggt tatattatga gttggttatg
    13501 gacattgatt gttggagccg tgatcggagc aattgcaggt gcgatcacca gtaaaggaaa
    13561 ttcgatgggc tgtgtaacga atatcattgc tggactagtc ggttcaagta ttggacaagc
    13621 gattttcggc gaatggggac caaaagctgc aggtatggca cttattccat ctattttagg
    13681 cgcagtgatt ttggtagcag ttgtctcatt tttctttgga aaacgatcat aagtttttac
    13741 aaaatagtaa actaaaagga gttgcagcga gactgtgact cctttttggc tttatttatt
    13801 taaaataaaa agaagttttc cggaaatttt tatttaactg tcgtgtacga agaaaagttt
    13861 gctataatgg aaaaaagcgt gcaaagaaag agggagtttc attatgatgc tacgtgtaga
    13921 aaaattgcgc aaaaaaatgc aagaagaaaa tttggattca tttttggtta ccagtccgta
    13981 caatcttcgt tacttaacga actttacagg tacgacagga ttagctgtta ttactttgga
    14041 aaaagcattt tttattactg attttcgtta taccgagcag gcggcagcgc aggctcaagg
    14101 gtttgaaatt attaaaaatg tcggacctat ttttgatgag gtagcaaact tagtacgcaa
    14161 agaagaactg cactcattag cttttgagga aacaacagtc tcatttttag aatattcggt
    14221 tttagaagaa atcatcgatg cggaattagt acctgtttca cagatgatcg aagaactcag
    14281 agaagtgaaa gatgaagaag aaatcgctat tatcgaaaaa gcatgtcata ttgcggatat
    14341 ggcatatgat cacatcctga aaatgatcca accgggcatg actgagattg aagtcgcaaa
    14401 tcaactagac ttttatatgc gttctcttgg cgcttcaggt gtttcttttg atacgatcgt
    14461 tgctagcgga ttgcgttcgg ctatgccgca tggtgtagca agcaaaaaaa tcatcgaaca
    14521 aggtgacttg atcacattgg actttggttg ctattacgaa gggtacgttt ccgatatgac
    14581 acgtacattc gctattggtg atcctgggga aaaattaaaa gaaatttatc aaatagtctt
    14641 agatgctcaa ttagcagtta ttgatgctgc aaaaccagga atgactggtg tccaattaga
    14701 tgcagttgct agagattata tttcaaaaca tggttacggg gaagcatttg gacattctac
    14761 aggacatggg atcggtttag agatccacga aggaccaaac gtttcttctc gtgcagaaaa
    14821 gcaatttgta ccaggaaatg tgatcactga tgaaccaggg atctacttac caggaatcgg
    14881 tggagtacgt attgaggatg acttgttgat cacagaagat ggaaatcgtg tgttgactcg
    14941 ttcaccaaaa gaattgatca tcttatagtt tcatcaatag aagaagtaag cgtaaaaatc
    15001 agtgttcaca gactttgtta tagaaaatca ctcgatttaa tgatacacta tagaagaact
    15061 tttaagctgt aagagataat aaagttgggt gttttctcca attcatagca gtttgcagct
    15121 gatcggcggc agttttctta ccacgtgatc actatgccgc atcatagaga attcggatgt
    15181 atctcgtgct taggcaaagg gaggaataaa taaatggcag atgaaaaaaa tttgatttta
    15241 aacgcaaacc aagatttagg agagatcgtg atcgctcctg aagtcatcga agtaattatc
    15301 gggattgcag cttctaaagt agaaggcgta tacggaatgc gcggaacttt tgccagcaat
    15361 gtcactgaat tattaggacg tgcagctcac ggaaaaggtg tttacttagc aaacgaggaa
    15421 gatggcttga aagtagatct ttactgttat ctagaatatg gtgtttcagt tcctaaagta
    15481 gcaatggaaa tgcaggaacg ggtcagccag caagtccttt tcatgacgga tatcgattta
    15541 tctgaagtca atatccatgt agtagctgtt gttcctgaaa aattagaaca accaacaatc
    15601 gaagaacttt ttgaagacga agaggaagag aatgaataaa gaattatcaa gacacgagat
    15661 tcgggaaatg gcattgcagg ctttatttcc attagacttc aatgcagacc taacaaaaga
    15721 agatgcgatt ttcaacgcaa tcgaattaga ccaccgcgac atgatcaacg aagatgaatc
    15781 agagtttgtt cctgtttatc ttgatacgct agttggcggt gtctgtgcaa aaaaagatga
    15841 attggataaa gtgattgaaa aacatttaaa aaacaattgg cacatcaatc ggatctcaaa
    15901 aatggatttg gtgatcttgc gtatcgcgat ttttgaaatg acttatgtga cagatgtacc
    15961 agcggctgtt gctttaaatg aagcaatcga gttggcaaaa acatttagtg atgaccgttc
    16021 acgtaaattc gtcaacggtg ttttatccaa tgtattgaaa gaattagaag ctggggcgta
    16081 agtcctagct tttttctatg aatcatcata aacctgttat aaatcgggaa aattctatgg
    16141 tagaatgaaa acacaaaaaa tatctgggag tggttagatg gcagaattga ttaacggaaa
    16201 agaattagct gaaaaaatgc aggcagagat tgctgaaaaa atccaaaaat tgaaagataa
    16261 tggtatccat cccggattag tcgttttatt ggtaggggaa aatccagcca gccaaatcta
    16321 tgtaagaaat aaagaacgtg tagcaaaaga aatcggaatc cattcattgg tagagcgtta
    16381 tcctgagacg atttctgaag acgaactact tgcagaaatt gaaaaataca atcaagatcc
    16441 tagttttcat ggtatattgg tccaattacc attgccaaag catatagatg aagaaaagat
    16501 cctgttagct atccgccctg aaaaagacgt agacggtttt catccgatga atttaggcag
    16561 actccttgcg ggtaaaccgg acaagattcc ttgtactcca tacggcatca tgaaaatgtt
    16621 tgaagcttat tctatcgatc cggcgggtaa acgagcagta gttatcggac gaagcaatat
    16681 cgtcggtaaa ccgatggctc agctactctt gatggcagat gcaactgtta ctgttgctca
    16741 ttctaaaacc gaaaatctgg ctgaactggc acaagaagca gatattttag tcgtagcaat
    16801 aggacgtgga cattttgtca caaaagaatt cgtaaaacca ggtgctgtag tgatagatgt
    16861 agggatgaat cgtgatgcta acggtaagct gatcggtgat gtgaaatttg atgaagtgga
    16921 gcctattgca ggctggatca ctcctgtgcc aaagggtgta gggccaatga ctatcacgat
    16981 gctgatgtat caaaccgtaa aatctgccga agcttttgga gcaggtgaat agatggcaca
    17041 agaatattta actgtcacta cattaacgaa gtatttgaaa agaaaatttg atgccgatcc
    17101 ttatttagaa cgcgtatatt taacaggcga aatatcgaat ttccgtttac gtgccaatgc
    17161 ccatcaatat ttcagcttaa aagatgacca tgcaaaaata tctgctatta tgttcaaagg
    17221 agcattccaa aaattacgat tccagccaaa agaaggaatg aaagtccttg tcgttgggcg
    17281 tatttcatta tatgaagcgg gaggttctta tcaaatctat gtagagcaca tggagcctga
    17341 tggaataggt gctttatatc aagaattgga agaacgaaaa gaaaagctga tgaaggaagg
    17401 cctttttcaa gggcctaaaa aaatgctgcc acgtttccca aagcgaatcg cggtccttac
    17461 cagtccaagc ggagcggtta tccgcgatat catcacgacg gtgaaaagaa gatatccaat
    17521 tgtccaattg gttttgttcc caacagttgt acaaggaaac caagcagcgg acaatgttgt
    17581 caggaatatc cagagagtag aagagatggg caatttcgat acaatgatca tcggtcgtgg
    17641 gggtggttcg attgaggatt tatggccgtt taatgaagag cgggttgctc gggcgattta
    17701 tcaagctaat acgccggtga tttcatctgt aggacatgaa acagatacca cgatcgctga
    17761 tttagtagca gatgttcggg ctgccactcc aacagcagct gcagaattag ctgttcctgt
    17821 tttgtcagaa gagttgatgc gcattcaaga acggcaagct agattgcagc aggcgtttgt
    17881 acgacagatc cagcgcaaac aagaacggtt cgagcgtgct cgacgttcct atgtatttcg
    17941 gcagcctgaa agattgtatg aaggtcagac catcaaatta gaccagttga aacagcgatt
    18001 atatcaagct acacagcaaa tttatcatgc gaaagaaaaa caaacgatcg cattaagcca
    18061 ccaattggaa caagtggctc cgctttatcg agttaaagca gctcgccaag aaactgctta
    18121 tctagaaaaa cgcttagaag agaaaatcca acaatatatg aaacaacagc agcagcgttt
    18181 tgctcaagct gttcaatctc ttgatttgtt gagtccattg aaaatcatgg gaagaggcta
    18241 cagctatacg acgttaaatg atcaagtagt aaaaagtgtc accgagattc atcaagggga
    18301 tttgctgacg atccattatc aagatggaat cgttaaagga caagtacaag agatagacaa
    18361 aggagaataa aaatatggaa aatccaactt ttgaagagtc actgcaagaa ttagaaaaaa
    18421 ttgtcatgca gttagaacaa ggagacgttc cattagaatc agctctagat tcgtttaaac
    18481 gaggaatgga attaagcaaa cattgccaag atacattagc taaagcagaa gagaccttga
    18541 cgaaaatgat gacagaatca aatgaagaag ttgattttga cggaaacgag gaaagctgag
    18601 atgagattaa ctgacttttc agctattcat ctacctgctg tagaaaaaga aatcttgtct
    18661 tttttagatg agcatacaac ggatagagga ctctatgatg cgatgagtta ttcagtgaaa
    18721 gcaggcggga aaagaatacg tcccttatta cttttaacgg ccgttgcttc ctttgatgag
    18781 cctattgatg ttcccgtcta tcaagtagca gctgctttag aaatggtgca tacgtattcc
    18841 ttgatccacg atgatttgcc tgcgatggac aatgatgatc ttcgtagagg aaaacctacc
    18901 aatcataaag tattcggcga agcattagct atattggccg gagatggttt gcttacagga
    18961 gcattccagc taatcagtat ggcacactta ggtaattctc ctaagcttct gctgcttcag
    19021 caattagctg tttgtgcggg atcacaaggt atggttgctg ggcaagctgc agatatcgag
    19081 ggcgaatcga aaaagctttc tttagaagaa ttagcattta ttcatgaaag aaagacaggg
    19141 catttgattc gttatgcctt gctggctggt ggcatattag cgaagcaacc tgaagaaatc
    19201 ttattgctac ttcaacgatt agccgaacat ttaggtttag cttttcagat aagagatgat
    19261 ctactcgatg tgattggtac aacgaaaaca ttagggaaaa cagctggtaa agatgaacgt
    19321 atggaaaaaa atacttaccc gcgtttatta ggcctagaaa agacacgtga ggcgttggag
    19381 attgagctgt tatccgccaa caagatcata gacaaattag aagaggacgt tttttctttt
    19441 gatggcgggc tgatgcgcca gatgatcaag caatttgatg tggagaaatg agggaaagaa
    19501 tggaaaaaga acgcgtagat gtattagcgg tcaaacaagg attatttgaa acaagagaac
    19561 aagccaaacg ttcagtgatg gctggtttga tttacaacga aaaaaacgag cggtttgata
    19621 aaccgggaga aaaaattcca gtgagtagtg aattaagagt caaaggtaaa aaacttcctt
    19681 atgtttctcg agggggatta aaattagaaa aagcactcaa agcatttgat ctatctgttg
    19741 aaggaaaaac attgttagat attggtgcat ccactggcgg atttactgat gcagctttgc
    19801 aaaatggcgc aaaaatgagt tatgctttag acgttggcta caatcagcta gcttggaaaa
    19861 taagacaaga tcctagagtc gtcgtaatgg aaagagtgaa ttttcgttat gcaaaacccg
    19921 aagactttac cttaggaatt ccagaagttg ctgttatcga tgtttctttt atttcactaa
    19981 aactgatgct gcctccatta catgctattt taaaagaaga gggagaagtg attgctttaa
    20041 tcaaacccca attcgaagca ggcagagaag ctgtagggaa aaacggaatt gttcgtgacc
    20101 ctcagaccca tcaaaaagtt ttagaagaca ttttgtcatt tgcggcacaa ggtggatatg
    20161 atgtgctgga attaagttat tctccgatca cggggggaga aggaaatatc gagttcttgg
    20221 ctcacttgag gaaagtaccc gaaagcggaa caatcaattc agctattaat atggcagaag
    20281 tggtttcaaa tgcacacgaa cagtttgacc ataaataaat tgtaactgtg aaaatcaagt
    20341 gagaagtatg cggattcttc tttattatac caaggaaata agctatcatt gattaagaag
    20401 aatatgctaa ggagcgaaga cgtaatgaga aaaaaagatc ggcatcgttt gattactcga
    20461 ttgttgagtg agcaagatat ccgaaagcag gaagaatttg ttgaaatcct gaaaagcaaa
    20521 ggaatatctg ttactcaagc tacgatttcc agagatataa aggaactgaa actgatcaag
    20581 gtaccggctt cagatggcgg ctaccgttat agcataccag ctgaaacaaa cgaagatgta
    20641 aatactaaat tggaaaaact attaaaagac gctttcgtgg cagttgacca aatggaaaaa
    20701 tttgttattt tgaaaacatt gccgggaaat gcttcggcag cagcaaattt gattgataaa
    20761 cgttacaaga aagaattatt ttcgattatc aatgatgacg ataatgtttt gatgattaca
    20821 cgaactgaag accaggcagt tttattgaag aaagacttcc tgcattacct ttaagttgag
    20881 gagcgaatgt gatgctacaa gaaatcagta ttactaactt tgcgattatt ccggaattgc
    20941 ggctttcttt tcacgaagga atgaccgcgc tgaccggaga gactggtgcg ggtaaatcca
    21001 ttattatcga tgctttaggt ctgttagcag gaggaagagg ttcaagcgat tatatacgtc
    21061 aaggagcaga aaaatgtgtg cttgaagggt tgtttgaact accaaaacaa gaaggattct
    21121 ctgaactgat ggttgaatta gggatcgaaa cagatgagga caatctgatt gttcgacggg
    21181 atatgtcctt aactggaaaa aatgtttgtc gagtgaatgg tcatattatc acattagcta
    21241 atctgagaag aatcggcagt tatttagtag atatccaagg acaaaacgaa catcaggaac
    21301 tgctccagcc tgaatcacat cttgctttat tggatcgttt tggagatgta gctttccaac
    21361 agaagaaaaa gagttatcag caagaatata tctcttatcg tgagctggaa aaaagggtac
    21421 gaaaagtgca gcaaaatgaa aaatcctatg ttcagagaat agatatgctc catttccagc
    21481 aagaagaaat agctgctgct gatttgcaag tcggagaaga agagaaatta aaagaagaaa
    21541 gagaaaaact tagcaattat caaaaaattg ctgatggatt agctgcaggt tacggagcac
    21601 tgacgaataa tgaacaaaac agtgtagatg gtgttggctt ggccgtttca gaactgcaag
    21661 ggatcgccca tctagatgtg gagtatgaag caatttatga aaatatccaa agtgcttact
    21721 atttgctgca agatgcaatc ggcgatatga gtcgtcagat tgatttattg gagttagatg
    21781 agagtcgttt agaagaagtt acgcaacgtt tagaattaat ccgacagttg aaacgtaaat
    21841 acggcgaatc cattgagtca atattggctt actatgacga aatcaccgaa gagctagctt
    21901 cttctgattt ttcagaaggt caattggaca aaatgaaaga ggaactagag caaaaagagc
    21961 ttctacttca gcaacaagcc gcagatcttc atgaagcgcg taaaaaaatc gcaaaagaat
    22021 tggaaaaatc cattctgcat gaattgaaaa gtctgtatat ggaaaacact gagtttgagg
    22081 tacgtttctt aaaagaagaa aatagacaat tgaatcatga tggatttgac caaatcgaat
    22141 tttacattac gaccaatcca ggagagccac tgaagccttt ggtgaaagtc gcttctggtg
    22201 gcgaactgtc tcggatgttg cttgctttga aaactatttt ttcttctgag caaggtgtga
    22261 caagtattat ttttgatgaa gtggatacag gtgtgagcgg aagagttgca caggccatcg
    22321 cagataaaat ttctcaaata tcgaaatact ctcaagtttt gtgcatcact catctgcctc
    22381 aagttgctgc agtcgccgac tatcaatatt atattgtgaa agcagtgatt gatggacgta
    22441 cgcaaacttc tgtttcagag ttgaaaacaa aagaaagaga agaagaaatt gcacgtatgc
    22501 tggctggaag tgagattaca aaactcacac tcgaacatgc aaaagaacta ttgaaactcg
    22561 caaaaaggac ctgagccacc tcgcagtggt tcaggtcctt ttcagcagct gatagctata
    22621 ttttattttt acatgacact cattacagca gtcaatacaa cagatccaat cgttaaaatc
    22681 agcattgtcc aaatgacaaa ttttgttact ttagcaaaag tacttgtttg ttttttttca
    22741 cgcattgttt tcaacctcgt cattaattag ttgattcaag tgtacaatct tttttccatt
    22801 tccacaagag ggctttttta taaaaacttc ccttttttta aataataggt agttacgata
    22861 caaataaata atgttaatag aactagccat ataaaggcat catccctttc agcaataggt
    22921 aacttaatgt tcattccata gatactgccg acgattgtcg gtatagttaa aataatcgtt
    22981 aaagaagtta aaattttcat aatattattc agattattcg atacgattgc tgaaaaagtc
    23041 tgattcattt gttctactag ttttaattga atgcgagaag tagtcattgc ctgctctgtt
    23101 tccaccaata catcacgtaa atgatttttc aaagcatgat tttcttggaa aagtttattt
    23161 tgcgctagtt ctttcaatgc atctaaatta gcagaagtcg cttctctgaa ataaacgagg
    23221 cttttttgga tatccatgat ttgataaagt tgtttgtttt cagtggatac ttgaagtttg
    23281 gcttccaaag tatcgcattg agattgaagc gtagctaaat aactgttgta agagagtgtg
    23341 acctgccaaa tgaattgaaa gaagatattg agattaggcg aaatatcact ttttggaaag
    23401 gtctggctaa agactttctt taaaaacagt ggttcatgat tcgtaattgt gataagcttc
    23461 tttttgggcg tcaaaataat agagagcggg tatgtatcca cttgaaaata accgctagga
    23521 cttgttttag caaaaggata ttgtaacaat aataacgctg gctttgtcaa ctttgattga
    23581 ttgaattctt ctgtacggga attttctgca tcgtccaata tggaagtgat gtaatctgac
    23641 ggaatttcaa attgatgtgt cagctgatga atctcttctt gattaggacg ttctacacaa
    23701 taccagatcg tttggtcagt ttcctttccg gtattacgca gtttctcatt atctaatgta
    23761 aaatatttga tcatgatttt cctcctgttg cctgtttctt ttattataac ggatagggaa
    23821 ttggaataca tggaatgtgt ttgtaagata tagaatataa ctgcataaat ttaaataaaa
    23881 tgaaacagtt gtgtaaagta tatacagtat acttgaagca acgataaaaa aggagtttac
    23941 gttcatgggc acattcacac cacttatctt gttttggtat atttacccgg taatcgtttt
    24001 gtttggttgc caatttcttg taaaattatt ttcgttaaat cgtcgtttta aaataaaagc
    24061 ccctgatttg gcgattcctt ttttgtgggg cggtatgcat gcattgtcta gaaatacagg
    24121 gacaatttct atcttaccgt ttttctttat ttctgttttg ctaatgggaa tttgtattgc
    24181 tgttttccaa gcatattatt atgaagaaat tatttatccg cgttatttca agatgacttg
    24241 gcgtttggtt tttctgttga caatcgtctt gtacgctgtc ttgatcattg tgaacatact
    24301 ttcttaccta tgaaaaaaat agaaaagctg taaaaagtct tttaaaaggc tttttgcagc
    24361 ttgattttta aaaaaatgtt tatgaataaa aaaagttgtt cccggatttc ccagaaaagg
    24421 tggtagaaag tgggggattg tggtagacta attttagtta gtggaggaat ggggggcttt
    24481 caatgttgat gggtgaattc caacataata ttgatgcaaa aggacgttta atcgtgccct
    24541 caaaacttcg tgaagaactt ggcgaaaagt ttgttctgac acgcggattg gatggctgtc
    24601 ttttcggcta tccgatgagc gaatgggaaa atctggaagc taaactgaac gaaatgccgt
    24661 tggctaaaaa agacgcacgt acttttgtgc gattcttcta ttcggctgcc actgaatgcg
    24721 aacttgataa acaaggacga atcaatatac ccagcacgtt aagaaattat gcagctttga
    24781 caaaaggttg cgtagtcatc ggtgtatcta accgaattga aatttgggat gagacacgat
    24841 ggcaagattt ttctgcagca gcagaagaga actttgacga aattgctgaa agtatgattg
    24901 atttcggact ataagaatag gaagaggctg actaatgact gaaacatttc aacactatac
    24961 agtcatgttg aaagaaacgg tagatggatt gaacatcaaa ccggatggcg tttatgtaga
    25021 ctgtacactc ggcggtgccg gacatagtga atatttatta agccaactaa gttctaaagg
    25081 gcatctgtat gcgtttgacc aagatcaaaa agcaatcgat cacgccaagc tgcgtttagc
    25141 ttcttatgtc gaacaaggta tggtcacatt tatcaaagcg aacttcagag aattagaaga
    25201 acgcttgagt gagcatgtag ataaggtaga cggcattttg tatgatctag gggtttcctc
    25261 tcctcagcta gatgaagcag aacgtggatt tagttatcat caagatgcac cgttggatat
    25321 gcgcatggat cagtcagctc ctttatccgc ttatcacgta attaatgaat attcctacca
    25381 tgaattagta aagattttct tccgctatgg cgaggagaaa ttttccaaac aaattgctcg
    25441 tgaaatcgaa cgagtacgaa aaacaaaacc aatccaaaca actggtgagc ttgtcgaaat
    25501 cattaaacaa gtcatcccag ctcccgcaag aagaaaaggc gggcatcctg caaaaagaat
    25561 ttttcaagct gtgcggattg cagtaaatga cgaactcggt gccgaagagg cctctttaga
    25621 acaggcaatc cggttattga aagtcaatgg aagaatcagc gtaatcacat tccattcatt
    25681 ggaagacaga attgtcaaaa gtatgtttaa agaatatagt acggtacaag atctaccacc
    25741 gggacttcct gtcatacctg acgaattcca accagaactg aaagtcatta ctcgtaaacc
    25801 aatccttcct tcagaggaag agctaacaga aaacaatcga tcacgcagtg caaagttacg
    25861 tattgcagaa aaaataagaa tgaaagagga gtagaatgat ggcagaatta aagaaaatgc
    25921 aagattacga atatgattta cctgaattgg tggatcagcc ggaacaacaa atgcctgatt
    25981 cttcttcgaa tcaagaaatc attcttccac aatcaccggc aaaacgatta aagcagattt
    26041 ctgctttgga aaaaattgct gtggcaagcg tggcgattgc tattgttgct ttatgtgttt
    26101 taacagttat gctgcgcaca aatatcagcg gagctgaaaa agaaatcacg tcaatacaaa
    26161 cagaaatcaa tgataaaaag caagaaaaaa cgagtttaga acaagaaaaa aacgaacttt
    26221 ctcgtactga acggattaaa caaatcgcag aagaaaaagg attgtctatt aatgacgaca
    26281 atttaaggaa agtgaagtaa atgagtctta aaaataaaat tcggcggttt atggaaaaga
    26341 aaaatctaaa tccgatgaac aatcgcaaaa aagtaggtat cattttattt gctacgagta
    26401 ttggattgtt ctttttattt gccgtccgtt tctcgtatat cgttattgga ggtcatgttg
    26461 ctggtacctc attagctgaa aaaacaaaac agttgtacca aggaagtgaa gtagtaaaag
    26521 caaaaagagg aacgatttat gatcgtaacg gtgtggcgct cgcagaagat gcctcctctt
    26581 attcaattaa agcgatactc tcaaaaacat atacctctgg ggataaaaaa ctgtatgttg
    26641 aagaaaagaa ttttgataaa atagcagaaa tcctgcataa gaatctttct atagacaaaa
    26701 aagatgcact gaatatttta gaggacggcg caaaaaaaga gctgtatcaa gttgaatttg
    26761 gtagctatgg gaaaaatatc tcccaagaaa ccaagcaaaa catcgaagcg gacatgaaaa
    26821 aagaaggtgt cgctggtctt tattttgtcg accatcaggc tcggatgtat ccaaatggcg
    26881 tcttttcttc tcattttatt ggatacgcag ttccagacaa agatgagaat ggcttagttg
    26941 gtaaactagg tttggagtct gcttacaatg atatcttgag cggtaaagat ggtaagatta
    27001 tttatcaaaa agataatttt caaaatcctc tgccaggtac agtggcagaa gaagaaaaag
    27061 ctgtcgacgg acaagatatc tacacgactt tagacagcag actacaaagt tatttagaaa
    27121 cactgatgga tcaagtaaat gaagaatatc agccagaaga attgacagca gtcctgatga
    27181 aagcaaaaac cggagaaatc ttggcaatgg gacaacgacc tactttcaat cctgaaacaa
    27241 tggaaggatt gactggaaaa gatgctatct ggcgtaattt cttggtacaa gatagttatg
    27301 aaccaggatc aaccatgaaa gttttcacta ctgcagctgc tatcgaagaa ggagaattca
    27361 acgagaatga aaccttccaa tctggaaaaa tccaagtaga agatgctacg atcaatgacc
    27421 atgactttgg tgaaaaaggt gtgctgacca tgcgtcaagc tctttcatgg tcaagtaacg
    27481 tcgggatggt catactggaa cagcgattag gcggacgatg gtataactat ttacaaaaac
    27541 tgggatttgg acaaagtact cattctggat tagatgatga agaaaacggt gctttaccta
    27601 cattaaatat tgtcgaccga gcaatgagtg cttatggaca agcggtaggt gtgacgaatt
    27661 tccaaatgat gaaagctttc acttctattg cgaataacgg tacaatgatt caacctcgat
    27721 atatcagcaa agtggtggat ccccaaactg gagaagagcg aacaactcaa acagaagttc
    27781 tagggcaacc tttttcaaaa gaaacaacag aaaaagtccg tgaatatatg agagatgttg
    27841 tcgaaagcga aaactacggt agtgcttatg gtgtatatag tgtacctgga tacaatgtat
    27901 cggcaaaaaa cggaacagcc caaatcgctt ctgatacagg gggatatcaa acaggagata
    27961 cagcctacct gtattcgatt gtggagatgg ttccttctga agatccagac tatgtcttgt
    28021 atctaacaat gaaacaccct aagacatatg atcgaatggc attggctaaa atcgcaaatc
    28081 cattgatgaa acgggcaatg gattttaaag aaactgaaga agattcagat acagaaacaa
    28141 aaacagaaaa agtatccgta gccgattatc gtaatcttga agcggacgtt gcagcagctg
    28201 atgctcaaaa aagtggactg caacctgtag tgatcggtaa tggtaaaaaa gtacaaaaac
    28261 aatctactgc caacggtgat cagttgatct ctggagaaaa actgatccta tatactggtg
    28321 gtgataagct gatgcctgac gtaacaggat ggtcaaaagc agatatcatg aagctgggga
    28381 aaatcctcgg tattgaagtt agttttgatg gagatggtta ttgtgtcaaa caagaacttg
    28441 ctccatatga aaaaatcact gaagacaaac ttagttttac tttagaagaa taagaagaga
    28501 aataggagag aaaagagcat ggaatggaca caagcattga ttcccattgt cagcagttgt
    28561 gcaatgacaa ttgccgcaat gccgctattt attggttatt ttcaaatgaa aaagcaaggt
    28621 caggcgattc gtgaggaggg accaaagtgg cacaatagca aagccggaac tcctacaatg
    28681 ggcggcttag tgtttctgat cggctctatt ttgacaggaa tttgggttgg agcttggcaa
    28741 aaacagctaa ctcctactct tttcatcttg ctttttgtat tagcgttata cggagtaatc
    28801 ggctttcttg atgattttat aaaaatattc aagaaaagaa acatgggact gaactcgaag
    28861 cagaaattga ttggacagat tctaggggga atcatctttt atcttgttta ccgttctgaa
    28921 ggttatccag gtgtattgaa tttcttcgga ctagatctac ctttaggaat catttatggt
    28981 attttcgctc tcttctggct tgttggattt tcaaatgcag taaatctgac agatggcatc
    29041 gatggattag ttgctggctt aggaagtatc tcttttgcag cttacggtct aattgcttgg
    29101 catcagcatc agtatgatgt attaatcatt tgcttaagtg ttttaggagg tttactgggt
    29161 ttcttcgtct acaacagaaa acctgccaag atttttatgg gagatgtcgg ttcattagcg
    29221 ttgggcggac ttttagcggc aatttctata atgctaaacc aagaatggac attgcttttg
    29281 attggtttga tctatgttat ggaaacagca agtgtgatgc ttcaagttac ttcctttaag
    29341 cttacaggaa aacgaatttt taaaatgtct ccaattcatc atcactttga aatgtgcgga
    29401 tggtcggagt ggaagattga tacagttttt tggttgatca gcattgtgac ttcgttgatc
    29461 acattatgga tcgtttggta ggagatgacg ggaaatgaaa aaaatatcaa catatgaaaa
    29521 taagaaagtg cttgtcttag gactcgcaaa aagcggagta agtgcggcca aattattaca
    29581 tgaattgggc gcacttgtca ccgttaatga tggaaaacct tttgacgaaa atccggaagc
    29641 acaagagctg ctttctttag ggataaaagt aataacaggt agtcatccaa tcgaattgtt
    29701 ggatgaagaa ttttcattga tggtcaaaaa tccagggatt ccctacagtc atcctttagt
    29761 agcaaaagcc caagaaatgg gtattccggt aattacggaa gttgagctag cttacgaagt
    29821 agcggaatgc ccaattattg ggattacagg aacgaacgga aaaacaacga caacaacgat
    29881 gacaggacta ctactgaatg caggagcaga tcaaggaatt gcacgtttag cgggtaatat
    29941 tgggtatcca gcaagtggtg tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga
    30001 attgtctagc ttccaactca tgggaatcac agatttccgc cctcatatag cggtgattac
    30061 caatatctat gaagcacata ttgattatca tggtacaaga aaagaatatg tcaaagctaa
    30121 atggaacctt caaaaaaaca tgacagaaaa agattatctg atccttaact ggaatcagtc
    30181 agaactacaa gaattagcgc aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga
    30241 agtgttggaa gacggtgtgt atgctgacga ttactcaata tactataaaa aagaaaaaat
    30301 aatggaaata tctgaacttg gcgtaccagg taagcataat gtagaaaatg cactagctgc
    30361 tatttctgta gcaaaattgt atggtatatc aaatgaagct atacgagaaa cgttgcattt
    30421 tttccatggc gtaccacatc gtacgcaata tgtaggagaa atccaaggca gaaaatttta
    30481 taatgattca aaagcaacca atattttagc gactaaaatg gctctaagtg gatttgaaac
    30541 gtctaaggtc gtgttattgg ctggcggatt agacagagga aatacatttg atgaattaat
    30601 tccttcatta aaaggaatca aagcaatggt cgtatttggc caaacaaaag aaaagttgat
    30661 ggatgctgga aaaaaagcag gcatcgagac aatagtaaca gccgattctg tagaacaagc
    30721 agttccttta gcattagaaa acagtacaga tggtgatgta gttttattat caccagcgaa
    30781 tgccagctgg gatcaatacc caaattttga aactagagga aacagattca tggaagctgt
    30841 gaaccgatta aaatagaaaa agtagaagcg agcgataaaa aatgaaaatt ttggttacag
    30901 gcggaggaac agggggacat atttatccag ctcttgcctt tgtcaattat gtaaagactc
    30961 aagaaccgaa tgctgaattc atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg
    31021 tccctgatac aggaatgcct ttccatacct tggagattca aggatttaaa cgaaaaattt
    31081 ccatgcataa catcaagacg gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa
    31141 tcctcagtga ttttcaacca gatatcgtta tcggtactgg aggatatgtt tccggagcgg
    31201 tagtgtacgc tgcagccaaa atgggtattc caacagttat ccatgaacaa aacagtgtac
    31261 caggtgttac caataaattt ttaagccgat atgtggatcg gatcgctctt tcatttaaag
    31321 atgcggcttc cttttttcct gaaaacaaag cagttcttgt aggtaatcct cgagcacaag
    31381 aagtagcaga tactaaaaaa tcagatattt tgaaaacatt tgatttggat ccagaaaaga
    31441 aaacagtctt gatttttggc ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag
    31501 tttttttaag tgaatatatt ccttcttctt accaagtttt gtatgcttca ggagatagat
    31561 attatgaaga gatcctaaat aaaataaatc ctgaaataca aaatattagt gtccagcctt
    31621 atatcaaaaa tatggcagag gtcatggctt ccagtgatct gctggtgggg cgtgctggtg
    31681 caacttcgat cgcagaattc acagctctgg ggttaccggc agtgttggtt cccagcccat
    31741 atgttacgaa tgatcatcag actaaaaatg caatgagtct tgttcacgca ggagcagcaa
    31801 aaatgattgc agataatgaa ctaacaggtg aatcactaag tcagacagtc aacgaaatca
    31861 tgggtgatga agaattgcaa aagcaaatgt gccgagcttc taaagaacaa ggaatccctg
    31921 atgcttcaaa acgtctttat gacttagtaa aacaaataat caaaaaataa aggcggtggt
    31981 cttagtgagt aagaaaaaag aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa
    32041 tttgactcct tggcaaaagg ctaaccgaaa atatctggca gaacaagaga tgaaaaacca
    32101 agagccaaaa aaagaagaca taacattaga tacacccctt tcagattctg aagaagaaaa
    32161 aacggttcaa gaggaacagc aagaagaaag ccagtccgag aaaaaaatcg aattttttga
    32221 agagatcaag caaaagaaaa acggtggacc atataacggt tcttttttga accggctgcc
    32281 caatttaaaa agtcaacggc acaaagtact atttcgtcgg ttagctttga tcatcactgt
    32341 attgggtata ccgctgattt ttttgatcta ttatgtttct ccttatagca aattacaagc
    32401 agttgcagta tcaggcaata agacagtcaa cagccaagaa atcatctctg atacaaaatt
    32461 gtcattagga gaaaatgttt ggggacagta ttttcatcga tctacttata tcgatcgcct
    32521 taaaaaagca cagccaagaa tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt
    32581 cgatttggat gtaacagaat ataaagagat tgctttgatc gcaaaaaaca atcaatacta
    32641 cccagtgatt gaaaatggaa cagtattaga tgaaaaagta gcaaatccta caaaaaatct
    32701 ccctatcttg gaagagttca aagactctgc aaaaatcaaa gaattaacaa agcaatacaa
    32761 tcagttatca tcagaattac aaaaagcaat ttctgaaatc aagtacacgc caagagcaag
    32821 caataaaaat ctgatccaat tgaatatgaa tgacggcaat caagttattg taaatatcaa
    32881 taatcttgcg aaccaaatga aatattattc gcaagtagcc aaagatatgg atgaaaaagg
    32941 tgtgatcgac atggaagttg gtatcttctc gcatccttac ggtagcactc aagaaacgga
    33001 agaatcgggc caatcggaag aaacaactga aagtgaagaa aatgcggatc aaacaaacga
    33061 atcaagtgaa gaggcagaaa cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg
    33121 atcatctgat tcaaatgatt caagtgaaac aagtcaaata gaagataatc caagtacaac
    33181 tccgtcaagt ttaaatgaaa attgataaaa caactttaaa aagtaagaat gtactttcta
    33241 aaaaccagta atttatggta gaattggaag cagtgaatat atctattaat aagtatattt
    33301 taaaacggac gctagttgtt cgcttgtata tggaatagta agtaggaggg aatcccattc
    33361 atggcaaaaa caggaatgta tgtaggcctt gatattggaa cgacatctgt taaagttgtc
    33421 gtggctgaat atatcgacag ccaaatgaat attattggag taggaaacgc aaaatcagaa
    33481 gggattaacc gaggcattat cgttgatatc gataaaacgg tccaagcgat acaacgagca
    33541 gtacgacaag cagaagaaaa agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca
    33601 gcaaacatgc ttgaagtaga aaattgccag ggaatgattg cagttaacgg agattcaaag
    33661 gaaatcaccg atgaagatgt cagaaatgtg gcttcagctg cccttgttcg ttcaatacct
    33721 cctgaacgtc aaatcgtgtc aatattgcca caagatttta ctgtcgatgg gttcgaggga
    33781 atcaaagatc ctcgtggaat gatcggcgta agattagaaa tgtacggtct gttgtttaca
    33841 ggacctaaaa cgatcatcca taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc
    33901 aacgaaatgg tgattactcc tttagcgctg actgaatcaa ttctttctga cggagaaaaa
    33961 gattttggta cgatcgtcat tgatatgggt ggcggccaaa caacaacggc tgttatgcat
    34021 gataagcaat tgaagtttac caatcttgac caagaaggtg gcgaatttgt cactaaagat
    34081 atctctattg tattaaatac gtcatttaac aatgcagaag cgttgaaaat aaactacggg
    34141 gatgcatacc cagaacggac atcaccagat gaagaatttc cagtagatgt gattggtcag
    34201 tcagaaccag tgaaagtcga tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa
    34261 cagattttca acaaagcaaa agatgcattg gaccaaatcg aagcattaga gttgccaggt
    34321 ggcgtcgtat tgacaggcgg agctgctagt cttcctggtg ttgtggactt ggcacaagaa
    34381 atcttcggcg taaatgtaaa attgtatgtt ccaaatcaca tggggctgag aaacccggta
    34441 tttacaaatg taataagtat cgtggattat tcagcaaact tgagtgaagt gtatcaattg
    34501 gcaaaaattg ctgttacggg tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa
    34561 acaacaaaca catatgagag ctatgaagca cctgaagaaa caatctacga tgagccggaa
    34621 ccaaaagagt ccggagaaaa tgtaaaaaat aaaatcaagg gtttctttac aaatattttt
    34681 gattaattca tcctgggagg aataagatat ggaattctca attgataata atatcaatga
    34741 cggcgcagta atcaaagtca tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat
    34801 gattgaagaa aacgttaaag gtgttgaatt cattacagcc aacacagacg tgcaagcatt
    34861 aaaaaattca aaagctgaaa cagttatcca attaggcccc aaatatactc gtggtttagg
    34921 tgctggttct cagccagaag ttggacaaaa agcggcagaa gaaagtgaac aatccttacg
    34981 cgaagcttta gacggtgcag atatgatttt catcactgca ggaatgggtg gaggaaccgg
    35041 tacaggtgct gcaccaatcg ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg
    35101 tgtcgtgaca cgtccattca cttttgaagg accgaaacgt ggccgttttg ctgcagaagg
    35161 tatcgctcgt ttgaaagaaa atgtggatac attattaatt atctcaaata accgtttatt
    35221 agaagttgta gataaaaaga caccgatgct tgaagctttc cgtgaagcag ataatgtttt
    35281 acgacaaggt gtacaaggta tctctgattt gatcacagcg ccaggttacg ttaaccttga
    35341 ctttgctgac gtgaaaacag tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt
    35401 ggctagtgga gaagatcgcg tagtagaagc aacgaaaaaa gcaatctcct ctccattgct
    35461 tgaaacatct attgatggag ctgaacaagt acttcttaac atcacaggcg gtttggatat
    35521 gacattgttc gaagcacaag atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt
    35581 aaatatcatt ctaggtacat ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt
    35641 catcgcaaca ggtatcgatg aatcaaaaaa ggaacgcaag tctagccgac cagctagaca
    35701 agcacaaatg caatcacctg ctcaaaagac tgtattagat atggatcaag ctaaaccaac
    35761 ttcttcagaa gaagaaaaca gttttggcga ttgggatatc agacgtgaac aaaatgttcg
    35821 tcctagagtt gatgattcca attttgacaa tatcgaaaaa aaagaatttg atacattcaa
    35881 ccgcgaagaa acaaaatctc atggcgatga tgaattaaat acgccaccgt ttttccgtcg
    35941 taaaaaataa aggagaggaa gagcacatga ttgctgacaa cttgcagaaa atcaagcaag
    36001 aaattcagga ttcgtgtgct cttgttcatc gtgatccgaa agaagttaca ttagtagctg
    36061 taacaaaatc tgttgaatcc gctcaagctg aagaattggt tagagctggc gttatgaatt
    36121 gtgcagaaaa ccgagtagat aaattattag aaaagaaaca agatttattt gattttcctg
    36181 aaataaagtg gcatttaatt ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg
    36241 aaattgatta ctttcatgcg ttggacagtt taagattagc agaagaaatc cagaagcggt
    36301 tagagaaaga attatcctgt tttattgaag taaatgtttc tggtgaggaa tcaaaacatg
    36361 gaatttcacc agatgagctt ttaccgtttg tggaatcttt agctgcctgc acaaaaatca
    36421 aggttgttgg gttgatgact atggcgccta aagaagcttc tgatgagcaa atccataaag
    36481 tgtttggtac gctgaaagaa ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac
    36541 catgtagtga attaagtatg gggatgagtc aagactttca aattgcgatt gaagaaggtg
    36601 caacatttat ccgtgtagga acagcgctat tcaaagacga ataaaggagg aacaaaaatg
    36661 ccgcttttaa acagaggagc aattgctaat tttttcggat tagctgatga ggaagagtac
    36721 gaataccaag attatcctga aacaacaaaa aaggctgtac agccaactaa aaaaaataca
    36781 acacagaatc aatcaactca ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg
    36841 gcgacttcac gtcctgtaac gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt
    36901 gaactacatc aatcacctac aaaaactgta gcgaaagaaa gaacagcttc aagaacctct
    36961 acacaaccta aagcaaatct tgctggaaaa atcactgtaa tggaaccaag agcttattct
    37021 gaagctatgg cgattgctaa acgaatcatt gctggagaag caaccttagt gaattttcat
    37081 ttagtagaag aaaaacaagc gagaagaatc gttgattttc taacaggaac agtttatgca
    37141 ctagatggag atatcaaacg tgttggagat gagatttttc tttgtacacc gactgggatg
    37201 gagattgaca gttcaaccgc tcaatctttt gcagatgcga atttgtttga tctgtaagag
    37261 gaggaactac gatttatact attgcactat tacttcattt acttcaacgg gcagcctatt
    37321 tctatagcat tatcttgatg gtatatgcat tgctctcttg gtttccaggc gggtatcaat
    37381 cagggctagg acgattatta gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc
    37441 tgcctttgag gattggaccc ttggatttca caattttagg ggcaatcctg atcttgaact
    37501 tagccgtaca aggtttagca cagatcgtta tatggataac tgtccattta gtttattgat
    37561 tgaagcaaca aaatctttat tctcagaata gataggaggg gaaaattttg gatgcaaatg
    37621 tataccagca ctttcgggca gatgaacgta catttatcga ttcggtaggc gattggattg
    37681 aacaggttca aggacaatat gcaccctatc tgaccgaatt tcttgaccca agacaatcct
    37741 atattttaga aacactgatt cgacaaagca gtgatttgcg tttcatgttt tatggcggat
    37801 atgaacaggc agaaagaaaa agatgtttga ttttccccga ttattacgaa cctgtagagg
    37861 aagattttga aacagcattg tatgaaatcc attatcctag caaatttgcc agcctaagtc
    37921 atgggaaaat ccttggaact ttagtgggaa cggggatcaa acgctcttac tttggcgata
    37981 tcatctcgga cggtgatcgc tggcaagtat ttattgcaaa tgaggtggat cattttgttg
    38041 ctgcacaagt aacaaagatt ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag
    38101 aaatgattat gccgaaagat agctggacac aagaaagagg aacagttagt tccatgcgac
    38161 tagacagtgt gatctctgag atttataata tttccagaca gcggtccaag cagctgatcg
    38221 aagctggtaa agtaaaagtg aactggacag aaaatacaag acctgatttt gtacttgaac
    38281 tattagatat tatttcagtc agaggttatg gcagagtcca gatccaagaa cttgagggga
    38341 agacgaaaaa agaaaagtac agggtactgt tcggtgtatt acgtaaataa aataaaaagg
    38401 tggtttactc atggctttaa ctccattaga tatccaaaat aagacattcc cgacaaaaat
    38461 gcggggatat aatcaagacg aagtagatga tttcttagat ttagttgttc gtgactatga
    38521 ggaattgact caaagaaatc gagaattaga aaaagcagtc aaacattctg aagaaaaact
    38581 tgagtacttc aatgaattaa aagatgcttt gaaccaatca atcatcgtag ctcaagatac
    38641 ggctgataaa gtaaaaacaa gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca
    38701 aaacaaagca gatgagttag ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga
    38761 tgcagaagaa aaagcaagaa aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc
    38821 gacagaaact gaagatctta agaaaaaaac acgagtattc catcaacgta tcagcttgat
    38881 gcttgagtct caattagaac aagtgaaaag tccggaatgg gatgaaattt tacaaccatt
    38941 ctccagctac gtgactgaca gccatgaagt gatcaaagaa gttttagcaa aacagcttga
    39001 caatgaaaat gatactgatg taaactcaga cacaggagtc atagaagcac ctatgacggc
    39061 atttgataca caggctattg atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa
    39121 cagaaaagca ctttgttatt cttaaagcga gccgatgaga gtggaagttc ggtaagacac
    39181 tgcatggtga aagatcctct acttgagacc tgcttttccg aaattagagt aagaagcagc
    39241 ggctgacctc gttattggtc acagagagtt tgcactagat agatgcaact aaatttgggt
    39301 ggtaccacgg catgttcgtc ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa
    39361 taaaggagtg tatggttgaa tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt
    39421 ccctatgcgt ggtaatttgc caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa
    39481 tcgaatctac caaaaaagac aagagttgaa cgaaggaaaa cctagctttg ttcttcatga
    39541 tggacctcca tatgccaatg gtaatatcca tttaggacat tcattgaata aaatcagtaa
    39601 agacattatc attcgttcaa aatcaatgtc tggctatcgt gcaccatatg ttccaggatg
    39661 ggatacacat ggattgccga ttgaacaagt attggctaat aaaggcgtga aacgtaaaga
    39721 aatgtccatg gcagaatact tggaaaaatg tcgtgaatat gcactttccc aagtagataa
    39781 gcaacgagca gatttcaaac gcctaggagt tgcaggagat tgggaacatc cttatgttac
    39841 attagatcct tcttatgaag ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaagg
    39901 ctatatttac aaaggattga aaccaattta ctggtctccg tcaagtgagt cttctttagc
    39961 ggaagctgaa attgaatata aagatgtaaa atctccatct atttttgtag ctttcaatgt
    40021 caaagacggc aaagatattc ttgatgaaga tacagctttt gtcatttgga cgacaacacc
    40081 atggacattg ccagcaaacc aaggtattgc tgtaaatcca aaatttacgt atgtattggt
    40141 ggaagccgat ggccgtaagt ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga
    40201 aatcggttgg gaaaatgtaa cagttctaaa agaatttgct ggacaagaaa tggaatatat
    40261 gactgcaagt catccattct atgaacgtga atcacttgtg attttaggcg atcatgttac
    40321 tttagacgct ggtactggat tagtccatac tgctccagga catggggaag atgactatat
    40381 cgctggtagc aaatataaac tatctgtagt gtcacctgta gactcaaaag gattgtttac
    40441 agaagaagca cctggatttg aaggtatctt ttatgacaaa gcaaatccta tgatcactga
    40501 tctattaaaa gaaaaaggag ctttgctgaa gctagatttc tttactcata gttatcctca
    40561 cgattggcgg acgaaaaagc ctgtgatcta tcgggcaact ccacaatggt ttgcatctat
    40621 cgataaattc cgtcagaata ttttggatga agtagaaaaa gtagagtggg ttatcccatg
    40681 gggtaaaaca cgtttgtata atatgatccg tgaccgcggc gattgggtaa tttcccgtca
    40741 gcgtgcatgg ggagtaccac ttccgatttt ctatgctgaa aatggagaag caatcatcac
    40801 accagaaaca atcgaacatg tggcaaaatt atttgctgaa catggatcaa ttatctggtt
    40861 tgaaaaagaa gcgaaagaac ttcttcctga aggatttacc cacccaggtt ctcctaatgg
    40921 cgaatttaca aaagaaaaag atatcatgga tgtctggttt gattctggtt cttctcatga
    40981 agctgtttta cgtcagcgac cagaattatc attcccagca gatatgtatt tagaaggatc
    41041 agaccaatat cgtggctggt tcaactcaag tatcacgact agtgtggcta tcaatggtgt
    41101 agcaccatac aaatcagtta tttctcaagg atttgcttta gatggtgaag gccgtaagat
    41161 gagtaaatct ttaggaaaca tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga
    41221 tatccttcgc ttatgggtat ctagtgtaga ttatgaagca gatgttcgtg tttctatgga
    41281 tatcttaagt caagtggcag aagtatatcg taaaatcaga aatacgatgc gtttcttatt
    41341 agcgaataca gaagatttcg atcctaaaaa agatactgtt tcgtacaatg atttacgttc
    41401 tgtagacaaa tatatgaccg ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg
    41461 gtacgacaaa tataacttca tgcatattta ccgtacagtt atgaacttct tgacggttga
    41521 tctatcgtca ttctacctgg attttgctaa agatgtagtt tatattgaag cagaagatga
    41581 ttatcaacgt cgttgcatgc aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt
    41641 attgactcct atcattccgc atacagcaga agaaatctgg tcattcctga aagaagaaga
    41701 ggagtacgtt cagttaagcg agtttcctgg ttatgaagag tttgcaaacc aagaagaatt
    41761 gatggatacc tggactgctt tcatggactt ccgtgataat gtcttaaaag cattggaaga
    41821 agcaagaaac agcaaattga ttggtaaatc tttggaagca aaactaactg tttatccaaa
    41881 acaacaagtt cgtgaaatgt taaaagcttt ggatgcagat attgcacaat tattgatcgt
    41941 ttcaccagac tactttgaag ttatggcagc agatgaacaa gtgccagata acgctatggt
    42001 atttgatgat gttgctatta cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg
    42061 ccaagttcgt aaagatgtag gagtagatga aaaacttcct catctatgcg gtcgttgtgc
    42121 aaaaatcgtt gaagacttct atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa
    42181 gggaaaaggg ggtgtgacat gttctttgtc acaccccctt ttgttatcaa tcgtttaatt
    42241 ttccacgttc acgataccag ttatctggtt gccagatcca ttcgaatccg tctttttcaa
    42301 gtagttcgaa agctgcttta ggtcccattg atccagcttt gtagttggga aaatccggtt
    42361 gtgtttggtc ccaagctttt cgaatgacat ccacgatatg ccaagattga gcgacttctt
    42421 cccaatgaga gaagttcgtt ccatcaccat tcaacgcatc taatagtaat ttttcgtaag
    42481 cttctgggct attttcaacc atttctgcac tatttctaaa ttccaatttg attggttccg
    42541 tttcaaatcc ttgccctact tctttcccat tcaaggataa agaaaatcct tcagttggct
    42601 gaatatagat cgttagaaca ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag
    42661 atgttttgaa tacattaaca ggaacttgtt tgaatacgat gttgatccga gtcccttttt
    42721 cagtcaaacg tttgcctgta cgtacataga aaggaacacc tgaccaacgg aagttatcga
    42781 tagtgaattt gcctgcgacg aatgtttcag tctctgattg agcatccact ttgtcttctt
    42841 cgcgatagcc cttgaattgt acaccatcca attcaccttg agcatattgc ccgcgaacga
    42901 agttttctaa cacttcttct tcgttataaa tgcggatagc tttcaatgct ttgatctttt
    42961 ctgtacggat ttctttttcg gaaaatgcta ctggcggttc cattgcaagt aatgctacaa
    43021 cctgtaaaat atgattttgc accatgtctt taagtgcgcc actatgatcg tagtagcccc
    43081 cgcgatcttc tacaccgagg ttttcgccaa aagtaatttg gatattgtcg atatagcgat
    43141 tgttccattg agcctcaaaa atattattgg caaaacggat agctgagatg ttttggatca
    43201 tttcttttcc taaataatga tcaatcctga aaatatcttg ttctgggaat acttctctga
    43261 tttgctggtt caattcaaaa gcagactggt aatcagaacc gaacggtttt tctatgatca
    43321 aacgattgaa gccatttttt gtcataatat tttgtgattt caaatgagaa acgatcgttc
    43381 caaaaaattg aggtgccata gccaaataat agacacggtt accgtttaat tgatagtgtc
    43441 catctaatcg gtcagacaat tcttttaatg tctgataatg cgttgaatca tttacatcat
    43501 gggattgata gtaaaaatgg cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg
    43561 cacggattgt ttctttgaca acttcacggt agtgctcatc gctccaggga cggcgagcgg
    43621 ttccgattac agcaaaatgc tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg
    43681 ggtacaattt acgctgggct aggtcacctg taccgccgaa tatcgtaaac aatacatttt
    43741 tttcattaga catgtggata cactccttta tattttatcg acaaaaatcg tgctggccgc
    43801 cttaaagctg acggggattt tctttctatc attttggata gtgatcggtc cttcataagc
    43861 tgcgatgtca acgatctcat attcttcgtt gatattcagg tcaatagtga ctaagtaatc
    43921 caacaattct ttttcatcaa gcactcgtgc gatacgcact tttgtaccga caggatagga
    43981 ctccaatgtt tgtcggcgtt cttcatggac aacttcctct tttttaggaa tcgatcctcc
    44041 atgaggacaa tgttcaggat gattcaaata gttttctaaa tgatctgcaa gatgttccga
    44101 agtcacatgt tccaatactt cagcatcatc atggacttca ttccagctat agtctaaatg
    44161 ttcaactaaa aaaacttccc ataagcgatg tttgcgaatc agactgctag ctttttgcag
    44221 tccgcttgca gtcaattgta caccttgata aggggaatgt tctacaagct cttctttcac
    44281 aagtttagaa atcatttcac tgacagatgc agctgagaca tctagactag atacgatttg
    44341 tttattgttg actttcgttg tatctccacc tagttctaaa atgattttca aataatcttc
    44401 tcgatttggt gtcatattcg atcatccttt catggtaaaa aaccatcatt agtaagtgta
    44461 acaaaaaaaa cgttaattga ctatttttct aaataaaaaa caaaggattt ttagacgttt
    44521 ttacaacaaa aaacgaaaga tgatagagaa gactcattct ttcgtttata aaggatatat
    44581 atatacattg ggagggatct atttttcaga taacaactta tatgaagtgt ctgcagattc
    44641 gtcataaaga gtttgttcgg gataagaaaa gataagataa aaaccatact gatcacgtac
    44701 gactaaacga tattcatcta tttctaccac agatgtgcca agagactgac cgttgatcaa
    44761 aaacgtgtaa tcagatgtaa tctgtaattg ttgtttttgc tggctatcac taaagaacca
    44821 tgtaccttga tactttgaga gtccttctga cttttccgct tgttttttct ttttcaagta
    44881 aataaaactt gagagaacgg taatgagtga accaagaaaa tagatcattt tttttatcac
    44941 caaatcactc ctttatgaga aaataatcgc atagacatat tctttcttct ttatttcatt
    45001 gtaccgaata aaagctaaaa tttctctaag actttcgact ggttttttta ctgtttttct
    45061 acaaattatg ataggataca tagtaggaag aaaggtgaca taatttgaag tatcagcaag
    45121 tggaaatagc tttttttatt gaccgcccga atcggtttat agcacattgt atgaaaaaag
    45181 acggagaaat aattattgcg catgtcaaaa atacaggtag aggaaaagag gtcctgatac
    45241 caggcgctga agtggctatt gtatttgctc ctggacctaa acggaaaacc gcctatgatc
    45301 tgattgctgt aaaaaagaag ggtgactggt ttaatatcga tagtcaattg cctaatcggc
    45361 tggcaattga tggtatttta gacggcacga tccttttacc aggattaact ggtccattta
    45421 cggtatacaa gcgtgaagta acttatcttc actccaaatt tgatatttat ttagagacgg
    45481 tggtcggaca aaaagcattt gttgaagtca aaggtatgac acttgaaaat aaagcgattg
    45541 gtgcttttcc tgatgcgccc acactcagag gattgaaaca tataggagaa ttaacgtatg
    45601 ccgcacaaga tggttatgcc gcttatgtct tgtttattgc tcagttcgaa catcttcatc
    45661 tggcaacgat ccatgaagaa atgcaaccag cactagctga tatggttcga catgcgcagc
    45721 aaagcggagt tcaaatcctc gcctataatt gtcaagtatc ggcagatgag gtaactgtca
    45781 agcaggccat tccatttgat gtagatatcc cttttgaaga tcctatacaa tagaaagaag
    45841 gtaaaataat gatcaactta ggtattatcg gaacaaattg gattactcat caatttgtcc
    45901 aagcagcttt aagcacaaaa aaatatgaat tgacagcggt atattctaga catttggaaa
    45961 aagcacagga atttggttct cattatgaag gggatatcga attcgcaaca gatttgaaga
    46021 cttttttcaa tattactcat atggacacca tttatattgc ttctccgaat agtcttcact
    46081 ttagtcaagc taagcaagca attttggcag gaaaaaatgt gatagttgaa aagccagctt
    46141 tttcgacgcc aaaagaaatg gatgaaatca tccatttggc aaatgaacac aatgtgtatt
    46201 tttttgaagc agcaagaaat atccatgaat caggttttaa aaagattgcc gattacttac
    46261 cattaaaaga cgagataatc ggtgcaaatt tcagctatat gaaatattct tcgcgctatg
    46321 accaagtatt agatggagaa gaaccgaata tcttctcgac tcatttctca ggtggtgcat
    46381 tgatggattt aggtgtttac cttgtatatg cagctgttgc ttggtttgga atgccaaaag
    46441 aagtccatta tttcccaaga aagatttcta ctggtgtaga tggtcttgga tgggggatct
    46501 tacgttatga gaattttgat gtatcgatcc agccaggtaa aatcggtgat tcttatttac
    46561 cgtcagagat ttattttgac tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac
    46621 aagcacaatt tcatgatcgc gcgcataaag aaatcattga tttggcggta acagctgcag
    46681 aaaatccaat ggcagatgaa gcagaggatt ttgccaatgt catggctcat ccgaaagatc
    46741 cagcttgggg attgttgtat gaagagtgga tcgagctagc tagaaatgtg aaccaagtga
    46801 tttatgattt aagaaaaaat ggcggcatca aattcgatgc agataatgag gaagattttt
    46861 aatgaacgaa tttgtacaag tatttcccga aaattggcag aaaaaatatg aggataaagg
    46921 gtttatctca ccttctctta ttcaacgagc agtttttcag ccactaagta ataaacaaag
    46981 tatagtagcg gtttctccta caggttcagg taaaacactg gcttatcttt ggcctctact
    47041 actaaacgtg gaaccaggtg aagcaagtgc gttggtcatt tttgcttctt ctcaagaact
    47101 agctattcaa gtagcagatg ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca
    47161 atctttggtg ggcggagcca acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga
    47221 aatcttgatt ggtacaccag gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc
    47281 acatcaagtg aaaacaatgg tatttgatga agcagaccag ctatttgacg ctgggaacag
    47341 ccaaatcatt gatcaaattc ttcatcaagc tccaacagag tatcagctag cttttttttc
    47401 agcgacagca gatcgttccc ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac
    47461 aattgacgtg acagcagagg acgattctcg aaaaggactg agacattact ttttacgtgt
    47521 accgatacga aagaaagatg actacttgag acgtctcacg catatagaag attttcatgg
    47581 tctgattttc tttaatcaac tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag
    47641 aggtgtaccg gtaggaagtc tggcctctga tcagaacaag ctactccgaa aagcagcgct
    47701 agaacaattc aaaaagaaaa tggtcagagc acttttgacc acagatgtgg cggctagagg
    47761 tttagatatt acaggtcttc cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc
    47821 ttatttgcat cgttcgggaa gaactggtcg aatgggtaat gaaggaatag taattacact
    47881 cgtacaagat aataatctaa gagatttaaa acggctttta cgtccatcaa atataacact
    47941 tgaagagatt tttttatacg gaggtaagct gcaaactgag cagccaacca aagaagatgc
    48001 agctcctgca gtaaataaaa agtatgcgaa aactttttct ggaaaggagc agaacccaga
    48061 atataacaaa gaaaaaataa gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa
    48121 aggagcaagg cgcaaataag cgccttttta tgctatgatt atgaaaacgg gaacaaaatt
    48181 ggttgccaga ggaggggtta tgtgaaagaa cgtcaagaag agatcttgca gctattgaca
    48241 gaaaaccaac aaggattgac agcaagtgat gtagctgagc gcttaactat cgatcgaagc
    48301 aatgcaagcc gatatttaag tgaactatac aaggcccatc atattgtaaa aaccgctggc
    48361 cgaccagtcg tttactcttt gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac
    48421 tcttctacgc aagtgacttt tgaaacactc gttggagaaa atgattcttt aaaagtcagc
    48481 atacagcagg caaaagctgc gattctttat ccaccgcggg ggttgcatac gattattttt
    48541 ggagaaactg gtacagggaa gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat
    48601 tcagagatgc tttctgcaga tgcgccattt gtttctttca attgtgcgga ttatgctcaa
    48661 aatccgcaac tgctctttgg acacatcttt gggatcaaaa aaggggctta cacaggagca
    48721 gctcaagata gtcccggtct aatagccaaa gcagacggcg gtatattgtt tttagatgag
    48781 atccaccgtt taccgccgga agggcaggaa atgctgttta ctttcattga taaaggtatt
    48841 taccgtccgc ttggagaaag tgcacaagta catgaagcat ctgttcagat cattggggcg
    48901 acgactgaat cttcagaaag tttcttatct acgttcaatc gacggattcc tatggcaatc
    48961 accttgccga atcttgcttc acgttcactg gatgagcgtt atgaaatcat ctctcttttt
    49021 atcaaacaag aagcgaatcg tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt
    49081 gccttcatgc tttatgatgc ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta
    49141 gtctgtgcaa aatctttttt acattaccgt actcatcatg agaaaaagct aatcattcga
    49201 aaagaagaac tttcccttca agtacaaaaa ggattactga aaatcaagga aataccggaa
    49261 cgtctcgacc gattcatgga cagcaaaagt cagtatttga catttgaacc aggatttgct
    49321 gatgttgtct ggtcacaaga tccagaacga aacatgcagg tctataacga tattgaggaa
    49381 aaagtcactt ctctttccga aaccggtgtg gagaacattg atctagagac cctcatttca
    49441 aaagatgtgg atgcttattt ccagacatat gtcaaagaat tgactaaaag ttcgattccc
    49501 aaagatcttt tgccagatga aatctggcgg ttaaccaatc aattgtatga tgtggctgaa
    49561 aaacggttag accgtattta taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa
    49621 agtacattgg atcgtgtgag agaaggtcat atgatcgtcc acccagattt gaataacgta
    49681 cggaaaaatt ttaagaggga attccaggta gcaatcgatc tttcaacgat cattgaagaa
    49741 gaagaacaag ttgagattcc ttttgatgaa atcggcttta ttagtatgtt tctttctatc
    49801 aatctaggag aaagtgagcc tgttaaagaa aacaaagtag atgttctcat attgatgcac
    49861 ggcagacaga ctgcttcaag catgttggag atggcacaag aactattagg aacaaaagta
    49921 gggaaagctt ttaatatgcc actggttatg gaagttcaaa caatgtatga agaagtgtta
    49981 caatatgtca aaaactatca agagcatttg acgaatggcc tactcttgtt aacagatatg
    50041 ggatcattaa acaccttcag tgatttgatt tatgaagaga ctggcattcg gacgaaagct
    50101 atcacgatga caagtaccat gattgtgata gaagcgatac ggatggcaag tgttggaaga
    50161 agcttagaag atatttatca aaatatccag ctttcctttg aatcgatcgt acgtgatcag
    50221 ttcaaagcgg aaaagtctga aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt
    50281 actggtgaag gagtagctgc caaattatat cagcgtatta tgccagtgat taatcaaaat
    50341 aaggtagaac tgatccagat gcagttttta gaacgtgaat cattcaaaaa acacatcgat
    50401 gccttattgg aagaatatga gatcaaagca attgcgggaa cagttgatgt tgattatcaa
    50461 aatatcccat ttttttcagc ctatgacgtt tttgatgatg aaaaactaaa tattttaaag
    50521 cgtatagctg atgatgagat cccgacggct aaaattgtcg attcacttgc tggatcatta
    50581 agcgatgtct tttctattga tgaactgatc cgttcattgc aaaagacagt tcagcagatc
    50641 cagaccgatt tgtcgattat cgtggaacct ggagtagata ctggaatcgt tatccattta
    50701 gccttcatgt tagacggatt gatcaaacaa gaaagccatc ggcaatttga gaaactgtct
    50761 attttctcaa aaatttatcg tttggaaatg gatatcgttc gggcaaactt gatggcacta
    50821 gaacgaaaat atcaggtaaa aattccagaa gatgatatcg catttcttac acaaatgttt
    50881 cttgaaaata aaataaaaaa atgaacacac taatcatact gtttacacac taaacatctg
    50941 tgtgcgcact ataaaaaaga gctaaaaagc atgaaaacgc tatttcagct ctttttttta
    51001 ttggcatgct tcttgcgtta tataaaagtg taaaaaaata aaaggagtgt taaaaatggc
    51061 aaaaaaaaca atcatgttag tttgttcagc agggatgagt acgagtttat tggtcacaaa
    51121 aatgcaaaaa gcagcagaag aaaaagggat ggaagccgat atttttgcgg tctctgcctc
    51181 agatgcagat aataatttag aatctaagaa tgtcgatgta ttattattag gtcctcaagt
    51241 acgtttcatg aaagctcaat ttgaacaaaa acttgcgcct aaaggtattc cattagatgt
    51301 catcaatatg caagactatg gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa
    51361 tctaatgaaa taaatcaagt atgcagttgg gggtataaca acgtggaaga tcaacaaaat
    51421 ctagaagcca tcatggggtt aatcatgttt ggcggtaatg caaagagcga tgcaatggaa
    51481 gcgattgcgg ctgctaaaat cggtgatttt gagttagcgg ataggaaaat cgctgatgca
    51541 gaagaatcac ttatacaagc gcatcatgca caaacagaca tgttgacaca agaagcacaa
    51601 ggaaatcata tgcaagtgac attattgact gttcacagtc aagatcactt aatgacatct
    51661 attgcgttta ctgatttagc aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa
    51721 taaatacaac ttcttttttg aacggaagaa gaaaaatttt tgaacggatt ttttattttg
    51781 ttataaggag aactctcttt atataaaaaa cttataggag gaagtaaaaa atgaacggac
    51841 tatcaagttg gatggagaaa tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac
    51901 atttagttgc tttgcgtgat gcttttatcg gcatactgcc cgcaacaatg gcgggatcag
    51961 tcgctgtaat gatcaatgca attattcgtg atttaccgca acagtttaac agtacctatg
    52021 ctgacagttt agcagcagac aaaggaatct ttgccgtatt gaatgtcatc atcggaatca
    52081 atggttttgt ctggaacggt acactagcaa tcgccggatt gatctttgcc ttttcttggg
    52141 ggtataatct tgcccgagct tatggagtaa atgatctagc tggggggatc gttggtttag
    52201 ctaccttgat tcaaggtatt tcctttggtc cagcattatc agcagcatta gatgtgaatg
    52261 ttccttcaaa tgtcgcagat gcaatcaata gttctgagat tggtgcaacg attgcagatg
    52321 gcacactgtc agttggatta tggggttggc taaaactaga tcatttgaat ggaaacgctt
    52381 attttacagt tatgatcatg ggagctattt cagtcattat tttttgtaaa ttgatgcttg
    52441 ccaacattac gatcaaaatg cctgattcag taccaccagc agtatctaaa gcatttgcag
    52501 ccattttacc agcgacgatc gctttatacg tcattgctat tatcaattat atcgtaggtc
    52561 gtgtagctga tgggcaactg atcattgatt tggtgcaaaa atatattgca gaaccattcc
    52621 taggattatc tcaagggttg ggagcagtat tgatcgtcac agtatttgtt caagtattct
    52681 ggttctttgg tattcatgga tcaaatgtat tggcaccagt gctagaggga atctggggac
    52741 aagcacaact aatcaatatt gatattttcc aaaaaggtta taacggaaaa actggtacac
    52801 cagccgtgtt agatgcaatc gaagatggaa aagcttatat gtgggtccgc ggatcgttcg
    52861 atgcttttgc atggtttggc ggatcaggcg gaacgatcgt cttactgata gctatcttga
    52921 ttttctctaa acgtgcagat tatctaacag tagctaaatt atccattggg cctggtatct
    52981 tcaatatcaa cgaaccagtg atgtttggtc tgccaatcgt attgaatgca atcatgttta
    53041 tcccattctt gattgctcca gtagtagcaa cagcaattgg atggacagct acttatcttg
    53101 gcctagtcgc tccggtatcg cagcaagtca catgggtagt accgccgttc ttattgtcat
    53161 tcttagcaac aggagcggat tggcgggcac cgatcgtaac attagtatgt atggtcgtga
    53221 ctttcttgat ttgggcacca tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg
    53281 aacaacaata agatgaacgt gaggagcggg acgctttaag tttcgttcct cataatgaat
    53341 tttcgaggag gaactgaaat gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa
    53401 gaattgttag aaggatacaa tgaagaagga atgactttta catttaaaga aaaacaagga
    53461 atcaagctgt tctttgaaac aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag
    53521 gaactaatca aagcacagcc ttggggaaca gtcctttatt ttcaatcaac agctgtttag
    53581 aaaatggttt aaaaagatag gatggttgag atgataaaaa acggtttatt tttatgtagt
    53641 attggttctt tgatcgtgtt gtatagtttg aatccacatt cgcaaaggta tgatttgtat
    53701 agtatggtca caggtctttt tctaacagga ttaggaatct atttcttcat gaaggggaaa
    53761 aaaagagaag aagcaaagga gaaaaataac taatggaaat cacgaaaaaa ttaaatattc
    53821 cagcatcgtt tttttacgat aaagttatgg actctgtcct tttcgatgta cgtaaagcga
    53881 ccggcaaatc agtaactaga aaacagctga aaaatttgga gtacgtcaaa caattctcgc
    53941 aaaataaccg ggctcgcata aaaatcgaag aagtcattga aaaccagtct tataagtttc
    54001 gtacatcgac aacgaagaat gaattcgtcg ttcattatca aatcaaacca ttggacgatt
    54061 cgacctgtga ggttcattac acagaaaaaa tggagtctta tggcatgctt caaaagttga
    54121 atgatatgct tttaggaaca atcttgatgt attttaaacg gagacgtttc aaaaaaatgc
    54181 tagatatgat cgaagcaacg tattaaatca atgaaacatg gtactattta gttattgaaa
    54241 aatgaagtaa gctagaagga atttttcata ggaagataga tctttcctgc gaatcctcac
    54301 tagctttttt gtaggaaggg gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc
    54361 ttcgattgag gaaatgtttg atttagccac ttatgcattt aatggggcag atacacctga
    54421 aaggcgagaa cgttttcgta cacttgcgga gaattcttgg aattacggat tttttgatga
    54481 ggaggatcgg ctaacaagtc aagtcatggc gacccctttt ccagtgaatt tttacggaca
    54541 agagtaccta atggccggca ttggctatgt tgcttcttat ccagaagcaa ggggacaagg
    54601 cgggatcaat cagatcatgg aaaagatcct tgaagattgc cgtgatcgta aagtaagctt
    54661 atcttatctg gcgccattct cctatccctt ctatcggcgc tatggctatg aacaatcatt
    54721 tgataaaatc agttatcaac taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg
    54781 aaaaataaag cgtatggatt ttgaagatgc aaaagctgca atcagaagaa tttatgaaca
    54841 gatgccggaa aaccaacgag ctggtctgaa gcgcgaagac tggtggtata cgtataaatt
    54901 caagcaaaaa ggcaattacc agtttgcttt gcattttgat gataatgagg aagcaacggg
    54961 atatatcgtt tatcagcttg caacgtcttc ctttattatt gcggagtggg gatttttgga
    55021 tcatgatgct ttttgcagcc ttgttcgctt cgtaagttct cacaatggtg cttttgaaac
    55081 atttgaatat tcatgcggct acggcggtaa tgatcaaaat tatctattag aaaatccatt
    55141 tgcttctgta atgatcacac cttatatgat ggcgaggatc gtagatattt ctttgttttt
    55201 ggaaaattat ccatttaaaa agagacaagc tgcatttgcc ctacaaatag aagaagatca
    55261 ttatgcgaaa tggaatgaag gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct
    55321 ctcaaaagta gaacaaacaa aactcccaat cgttcgagga agtatccaac atatcacgca
    55381 gctattatta gggtatcgta aagtggaaga gttggtattc caagaaagaa tacaggtgac
    55441 aaaagaatat gaagaaacgt taagctcaat cttgccacag caacagccaa ttcttaatga
    55501 ctatttttga taaaaaacgg gtgatgacaa tatttttgtc accacccttt tgtttttcat
    55561 ttggcatttg aaggaaaatg ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg
    55621 ttttcttttg ttttagggtt ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt
    55681 tcccgatttt ttttagatga atctaagcgt tctgcgtata ctttttcttt tggcttatca
    55741 ttcattggaa aggacctccc tacattattt cattctacct ctagtttatc atctgttaag
    55801 gactagtgga aacgttttgc ctaacttata agctgatttt tttagcagat aagcttgcaa
    55861 gtaaaaaaca aacaagctac aattgattta ttgaaattgt tcctgtagct cagtaggata
    55921 gagcaatcgc ctcctaagcg ataggtcgct ggttcaattc cagtcaggaa cgtataaata
    55981 acccctgtat cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa
    56041 ctagttatca tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc
    56101 ttcaagctct cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc
    56161 taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt
    56221 atgccttagt ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg
    56281 caaatatttg ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa
    56341 attatgaggg tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt
    56401 ttttaagaga tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt
    56461 tgtttttccc cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc
    56521 ttcgaaatcg atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc
    56581 accagcaact aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag
    56641 tttcattaaa gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga
    56701 atcttttcct ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac
    56761 ggcatctttc aacgatgctc taatatggtt attaaactta ataacggtgg attttacatg
    56821 gtctttcgca tacttattta aaaagcgttg atatccaact ctatctaaat cagaaatcaa
    56881 taccgctggc atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat
    56941 aggagatact gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa
    57001 tagatttttg cgatcccctt taaggccttt gttcaagtta tattctaatt cgttggcggc
    57061 atcttttgct tcgccttttg tcttaaatcc tgattttctt atcttcgtgt attttccgtc
    57121 atcttttttg tatgaaattt cgtattgcca actatttcca cgtttgacta atcttgccat
    57181 aattgaatct actctctttc tctgatacaa taggcactat aaagaagcct actgtatagg
    57241 tttgtttttc ttagaacacg cttgctttgg acggtgggcg tgttttttat ttattataca
    57301 gttgctttaa aaatagctgc tttttcaaat gatactaaag gagagaagtg gatttctatt
    57361 tctccctttt ggtttaacgt gaaatgagca gttacatcca tttgttttcc tggagcaaca
    57421 gatcccattg tattttcgtt ggcatatgtc tctgattttt tgtcatctgg tccatatact
    57481 tccacatctg tacctacagg gatatctgaa tcgccatcat tttttacggt ataagtaatt
    57541 tttactactt gtgcaggttg gttttcttca aattgatttc tttcatcagt tagttctaca
    57601 ctatttagtg tatattcagc atcaccaact tttacagtgt caccaatctt atagaaggta
    57661 tcgctttttt cttctttaga agatgaagca gaggttgaag atttagttac tttttcgcca
    57721 ccattatcac ttgctttatt actatctgat ccaccattta aagcagaacc aataattata
    57781 attaaaatta ctgctaatac ccaaaaccat acttttttgt aaaaaggttt actaacttta
    57841 tacatttttc cgtcttgacc cataactttt tttgccattt aaatattcct cacttcttgt
    57901 tataatatat ttgcgatctc agaaatgagg tatgagtccg tgttgcagca cgggcttttt
    57961 ttactgtgca taagagtatt ttttcttgaa atatgactgg caaacattaa aacattctgt
    58021 tcttaactta ttattgatag catagaattc cataaaattt tccaatttga actgagattc
    58081 atctgttaat tcattctcaa taaagatatt aagtagaatc ataattgcaa ttttatcagc
    58141 ttcagtttcg aattttgaat gaaaagttgt agagttatcg tacagtactg aatattcaaa
    58201 atgtgaagca atgaaatgac cgagctcgtg ggctaaatga aaagcttcag aactatcttc
    58261 gtgtagtttt tcgtttaaaa atactattct tggttttgga taataaaaac ctggttcttc
    58321 catttccata tagattaact ttaaattata ctcactcagc atttctttca actttaaata
    58381 catacaaccc atcactccaa ctattcattt tcctctaaag ctttagcaat tgcaatcgct
    58441 ttacgcattg tctccttaga tatttctttt ccatcaaaag aaaaaacagt atcgtcttct
    58501 gataaatcca catgtttagg ggtttctctt tcttctctac ctagaaggta gtctacagag
    58561 actccaaagt aatcagctaa ccgagctaac tcaatagaat taggagtttg tcttttccaa
    58621 cttcctaaat atccattcga atacccgaaa ttcatttcga gctgtctaat ggataatcct
    58681 ttttcttttg ctaactcctt tattatttcg taagtattca ttgataaatc aacctttctg
    58741 aatgcttaca aaaaaagttt agataaataa tgtaaaaata gttgacttat atacattatt
    58801 aatctatact atgttttgta aacaagttta acaactaaaa agacaacaaa aaatactatt
    58861 gattaataaa tgccaaccgc caagaaagct ttttaaatca aagtttagat gtcttattta
    58921 actatgcatt tagtatagat tattaatcta ataaagtcaa cgcagttttt taaaaagttg
    58981 ttaaatttgt ttacgaatat aaaagaaagg agagaagaat atggaaaaaa cagtctcggc
    59041 aaaaatcgaa gatttgaaat tagacatact gaaacaagca aaagtggcga tggaacacgc
    59101 ggtagataaa gaagactctg ccatggttgc agccatagca gagattttag ctcacgttta
    59161 gtcatcgttt ttacggtctt ctggaagctg accatagata acagcataat gaatatctaa
    59221 ataagcttga acaatttctt ttggcgaaat tgattcgcct ttagtagata cttgtgattc
    59281 gtgatttagc catgcaacaa ctaaatccgc agcgatttca aacggcgtta cactttgtgt
    59341 cagttgccat aaagaatttc acaatatgta tggtcgtggt aataatacca aagagcaatt
    59401 tgaggaattt atggaaatta aaaaatacaa aaaatcattt attaaaggag gctaaacaat
    59461 gaacaaggaa atgagccaaa caatcaaggt acaaaaaatg atagatgatc taacacatgg
    59521 aattgatagc caagccgata aaatcatcaa ggaattgcaa ggacaaaaag ttaaggatgc
    59581 aaaaatgctt ctcaagacta tcaactttga aatgaatcca acaaaaagaa agctcgccga
    59641 tgtgttggaa gaaaagttgg cttccgctat caacgagcaa gaattactat ttgaaaccga
    59701 tacttttaac agctgatgtt ttatagatga cagtttcatc cgaatctata tcatcgccga
    59761 gagaaaagaa tgttgctttt gacaaaaagc cgataagacc tacaagcggt cttgatgttg
    59821 caagagtaga taccccaata tcaccttgca aggtattcac gtaaatttga gaagaataga
    59881 acattccatc tttttcttcg atatttgacg catcatcgta tccaacgacc aaagtatcgg
    59941 caaatatttt gattttttct ccatcaagca tagtaattac aaattctggt ttcataaatt
    60001 ttcacctcct taacaattat ttcagcctgt cacactgata aggaaattat accaaagaaa
    60061 ggaatgagaa atatgaatac accacaaatt tttaatttcg agcaaaacga agttcgaact
    60121 attttagtaa atgatgaacc atattttgta ggaaaagatg tagcagacgt tctaggatat
    60181 tcgaatccgc aaaaagctat tcgagatcat gtggacttgg aggataagac gcagaacgat
    60241 tcgttcaccg tcaatggaac agcagttgtt ttgattaacg agtcaggcct ttacagttta
    60301 atcttaaaat caaaacttcc ctctgccaaa aaatttaaac gttgggtaac gagtgaagtc
    60361 cttccaacaa ttagaaaaac aggtagctat tcaaacgtac ctcaaagttt tgcacaagca
    60421 ttgcgtttag cagcagattt agaagaaaag aaccaattac tcgaacaaca aattgccgag
    60481 tacgaaccaa agattagcta cttagatacg attctttcat cgacagatac ggtagctact
    60541 tctcaaattg cagctgatta cggaatgtcg gcaattgctc taaacaaatt gctaaacgag
    60601 ttaggtgttc aacataaagt tagcggacaa tggatacttt accgaaaaca tatgaaccaa
    60661 ggatacacaa aatcgcacac aagtgagatt ccgaaagccg atggcggcac taaagttgta
    60721 atgaatacca aatggacaca gaaagggcga gtgtttattt acaacttatt aatcgcagag
    60781 ggctattacc ctcaaatgga tttagaggaa attggttaga aaggagtttt agtatgactg
    60841 acattgcaga aatcactcaa cgagatagag aaaaaatcaa agaatatgtc gaaagttcga
    60901 agttcttaac ttacaccatg cttgctgaaa gatttggaat tagcaaaagc tacttatctt
    60961 taattttaaa cggtaaaaag acttctgcag aagcaaatag aatcatagat tcgattatta
    61021 ctatgtacga attgtaaagg gaggaacagc taatgcaata tctagaagcg aaaatcccag
    61081 ttccagaagg ctatgtaatt atctcccaag tggattatga ggagttaaaa aaagctgatg
    61141 atactggtag atggatgacg ttgccagaag tgctagaacg gattaacaga aaatatgatt
    61201 ggtttacttc tagagtttta aagaacccaa gatatagaaa tattatcgat atcgaaaaaa
    61261 ataaaaatgg atttgtctat tatccagttg aaggaagaga cacatatcta tttttaagaa
    61321 gtaaaacact tgaattttta gaaacaaatt tttcggaaat cttaaggagg caagcggatg
    61381 ggaaaattta atagagcgct agtattcagc gcaccgctaa tcatctacgc tttaggactt
    61441 tggggaagca gacaagcgtt gataggaacg attgtttaca tggtttggat ttttatgggg
    61501 ctggatgaag ctgagtacaa aacaaaaaag ccagtcggga gggactgact aatgaaaaaa
    61561 agtttaatga ctataaacga aaaacaattg aaagaaaatt ttaatgatct catcaaagaa
    61621 tttgtaaaag aaactggaga atttcctaat caaattcatc tagttgcgga ggggcatagc
    61681 cagtatcaag ctgtgaaatt tgagatgaag aaacaaatct attgaattta gcagtacctc
    61741 tacttgtaag aacatttatt gtaatgtttt tttcgactaa agattcatcg tatctaaaaa
    61801 ccaacgtagt aatttttgac tcatacggtg gaatggtaat aggtaatgac aacggaggaa
    61861 attttgatag atcagcacct ttttttaaag atttaccaga atacgcacgt ataccatgtg
    61921 gaagttcgtc atacattgat tttaccgtta cagaataatt atcaccaatc attgtaaaag
    61981 catttaaatg atcaggaatt ccagaaatcg aaaactcaat aattgtaaca ggtaaagaac
    62041 tgttatttgt taacaataca gaatctataa tcctgaattt attttgatgg taaacatctg
    62101 gtttggaatc actttctcta tctatcaacc attcttcgca ttcagcgaag aaatccaatt
    62161 ttaaattaaa ttttttgttt tttctatctg tataggagat ataaaaagca aatgttgaaa
    62221 atactagaga cgtaataggc aaaataaaat ctttaatggt tttaacaatg ttattccagt
    62281 caaattgttt aataaagtca ataagactca atttatacca ccaccatttt ttatctacat
    62341 tatatcaaag aggagagaag aaataatgca agaattagta attttgaaaa ataaagaagc
    62401 tgtgactacg agtttgcaag tcgcagatag ttttgaaaaa gaacacaaaa atgttttgag
    62461 agatattgaa aagttaaaag aagatgtgct caattttgag cagatgtttg tggaaggtaa
    62521 tgaaccagat tcatacggca gaaatcgacg agttttcttc attagtagag atggtttttt
    62581 cttgttggct atgggtttta caggaaagaa agctatttac ttcaaacaaa aatacattga
    62641 agcattcaac gaaatggaag atgttattcg taagaatact gttcctcaaa caattgaaga
    62701 tatgatgatc taccaactag aagaaatgaa agatgttaaa aaagatgttt ccatgcttaa
    62761 agatactatg cgaattagtg ggcaacaaga gtttgaaatt aaacaaaaag gaaatataaa
    62821 agttatggaa gttctagggg gtaaagaaag ccgagcttat gaagaaatca gcaaaaaagt
    62881 attctcaaaa ttttggtctg aatttaaacg taccttttca atcccaagat atggcgagtt
    62941 acctcgtaag agattcgatg atgctgtttc atttattgaa atgtggttac cagaaactgc
    63001 gatccgcatg gaaatcgatc aactgaacag acaacaaaga cttttcggtg atgaaaatga
    63061 atagagctga agcgctaaga atcgggacgg taattgctaa tcgctggtgg agacacaata
    63121 aaccaatcat cctaagccaa caacatattg acaagcaaaa agcatggcaa caaataaaaa
    63181 agtgactccg ccggcaagca aagagtcaca aagaaaacac atcataagga gattttagca
    63241 tatggaaaaa gaactttcca ctctagatca atatttgact gatcctagtt ggggcaaatc
    63301 gaatatcaag gaaacaaata atcgaaaaat cagacgaaat cttttgacgg atgaagaact
    63361 agcatgtgat caagacgatt tgggaaattt tgtgagtatt tgggatcatg tctatcttat
    63421 ccatttatcg aggaagtcca aaaaacctga atatatctat gtcatcgaag atggcttgat
    63481 tgatgcgcta gaagagtatg acagagataa cttgattgat atctcttatt acggatcagg
    63541 taagaaatac attgctgaaa tggaggcaga atttgatgag tgaaaacaaa gggacaacga
    63601 cttttgaaaa actttttagt cgcaagttaa ataaaatact caagaaaaaa ggaaattttg
    63661 attatttatc ttgggctcac gcatgggaga ttatgaaaaa gaatgatcca caggcaacgg
    63721 taactattaa tgagtataaa cactacagag ttgtttctgg aactcatcaa gactttcttg
    63781 ttgaggaata taaacctttt cttatggatg aaactgggac ttatgtatct gtctcagtaa
    63841 cggttaaagg acacacggaa accgaattat ttcctgtttt agattatcga aaccaaccag
    63901 ttgttacgcc aaatgctatg caaatcaata actcattgaa gcgatgcttt gtgaaagcat
    63961 tggctctaca cggactggga ttatatgtat ttcaagggga agatattcca acaccaccta
    64021 gaatcgatac aaagaaatta aacatgctag agacgattct agaagctttc aatgagcaga
    64081 tgggtaaaga tatgaccaaa accttaatcg aatatgttaa tgagcagaca gataaattag
    64141 ggctcttagc tgataacgtt gaaactattg aacagttaag ctatgagcaa tgtgccttga
    64201 tggagcgagc aatagcagct aagagaaaag aattagataa gaagtgatat gagtgtttaa
    64261 accattaatc gattcatatt cagcggttct gaaaaagttc aaaggaaaag acataggtgc
    64321 aactattaat gaagaagtga acatcgaacg tttgaagacg atgtacgacg gatatgatgg
    64381 cgatcggatt attgaagttc gatttattga tcctagacgt ttcactgtac agcaacgaaa
    64441 cttcatctat gcgctcatag gcgatatttt catcgataca ggcatgccaa cggacttctg
    64501 gaaggaattc ttctactttc gttttgaagg cgtcacaggg cgcaaaataa gcctcaaaga
    64561 cgaatcgaat acaactgtga gtgatgctaa tgtcttagca aatatcatct tagatttcat
    64621 ctttgaacat catattcctt tcaaagaagg ctatgagatt ttaccagcga atcaagaata
    64681 ttacttctac aaatgcatca caaaaagagt ctgctgcatc tgtggcaaaa caggagctga
    64741 catcgatcac tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcattcaga
    64801 gtacacattt gcagcactct gcagaatcca tcacacagag aagcacaaaa taggtgtgat
    64861 taatttcaaa aataaatatc aaatcaaagg gatcaaatta aaccagaaaa caatcaaaaa
    64921 gttaaatatt ggagggtaaa aatgacagaa catcgaagtt attatgcgat tataccagcc
    64981 aacgtaaggt acgacaaaag acttaaacca aatactaagt tgttatacgg agagataacg
    65041 gccttgtgta atgaaagagg cttttgttgg gcaggcaatg agtactttgc agatttatat
    65101 ggtgtgaata aagagaccat atcgcgatgg gtaagtgatt tgattaagtt tggatacttg
    65161 aatcgggaaa tcatttacaa agagggtacc aatcaaataa tcaataggta cctacgaatt
    65221 aatcaatacc ctattgacga aaaacgcaat acccctattg acgaaaaagt caaagataat
    65281 aatacatcta ttaataatac atttaataat acaaaagaat atataagaga gttaccgcct
    65341 tcgaaaaaat cgaaggctaa gcccgtccgt cataaatacg gagagtataa aaatgttctt
    65401 ttgtcagatg agcagatgga gaaactcaaa acagaattcc ctaatgatta ccaagagcga
    65461 atcgaacgac tgtcagagta ttgtgaatca tctggtaaga cttataaaaa ctatttggca
    65521 actattcgaa gttgggcaag gaaagaaaaa agtgaaccta agaacgcaag cagtggatac
    65581 aagcgcacag gaagacgaga gaagcttcct gaatgggcaa tcgaccaaga agcctatctc
    65641 aagaaaaaag cgctagaacg agctaataga caatcaaaag caccattcta agaggtggga
    65701 aattgaaaat cgattatcta gaactaatta atgaaatagc aaagtataaa actggtgagg
    65761 aaatagaaat cctgagagac gtatatgatc aactcgaaga agctggaatc gaaggaatta
    65821 agaatgatcg ttcgagttgg agtaagctca gatactattt cgcactttat atcgatacaa
    65881 cacaattaag aaatttagca tataccaaat tactatttgt tgattgtgtt aaaggcttgc
    65941 aaaaacatct taatgaactt gagcaggtgt aatcagatgg acctaaagac atttacagca
    66001 cagattgaac taatgcatca agaagcttta agacaaagtg tatcgtacga agacaagtgg
    66061 ctcaacacgt tccacggcgg acgtgagagc gcacttgatc aagtactcaa attactgaaa
    66121 ggagaatgtc gggatggata agaaagcggc aatgcagcga attatcgaat tgacttattc
    66181 agaagattgg caaaatgaca aagaagctgc ttcagaagtg atgaggcttg gaagagcgat
    66241 gtgggcagac aagagcaaca agccaagacc acgaaaaatc gcaatttggc acggtgacaa
    66301 acttctagtg atagggacag ctgaacagtt agcaagtctc acaggcttgc acgagaaaat
    66361 cgtgaggaaa agagcaaggt gtggctacac agacgctaag aagagaacgt ttagatacgt
    66421 ggaggaatca tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcagcgt
    66481 gagattgacg atctggaacg aacaaaggca gtgatggtca atgaaacggc gagaaaggca
    66541 atcgatttgc acatagagaa tttaagaagg gaaatccatc gattggagga atgagcgtgg
    66601 ataagaaagc agcaatgaaa agaattgctg aattaaccaa gtcagaatct tggcaagaag
    66661 acaaagaaat agttgcagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccca
    66721 aacggagaac gccgagaaaa attgcaatct ggcatgatga ccgaatttta gtaacaggta
    66781 ctgctgaaca gttatctgaa attactggat taagcaaaaa cattatctgg gatagagcta
    66841 ggagcttatg gattgattca aaaggacgac agtttaggta tgtggaggag agataatgga
    66901 tctcattaca caatacagtg acatcatcct caagaaaatc atgatgaaga ttcagaaaga
    66961 taaaaaatca aaagaacgag ctgaattagt taagttagaa atggctgaaa caggagcagg
    67021 agtgcgaagt agcaggcatt ggaaagcagc agcaaacatt gaattttatt acaacgaaat
    67081 tcaaaaaggg ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact
    67141 tcatcaagat cgtttcaaat ttgtagagaa gtataaagaa atattagaag agtatttgag
    67201 gaggacagca aatgataaaa aaactcgttc aattcagcat ggatttatat gatatcgaat
    67261 caggagcaac actatctgtg gaatcggacc atctaatcat aaattttggt ggaaagcgcc
    67321 agattatttt gtgggtagtt gatgatgtac tgtttccaga aattgttcat gatttcgaag
    67381 aatcaaaagc ggttgagttt gaaatagtga aaaaagtaat ggaattgatt gaaaaatacg
    67441 aggaggacag cgaatgatac cgaagtttag agcgtgggat aaacgaaaga acgtaatgag
    67501 agatgtagcc gtcttgcatt ttactaaaaa cggcaaaaca aactttattg aatattggat
    67561 aaatcctacc gaattgaaat catatcacgt gcgaaacatc gacctcatgc aatccacagg
    67621 aatgaaagat aagaatggtg tggatatatt tgaaggggat atagtattag tcagcgtgcg
    67681 aaatggcttc gattacttag ataataaagt ctgtattgtc aaaaattcaa tagattattc
    67741 cggattagtt tgtgccactg ttgatgaaga cttagagtat caaattttta acacagagct
    67801 gtttgaagaa tacacgtacg aagtcaccgg aaatatatac gagaatagcg agttattgga
    67861 ggaacagcga tgaataaaca ggaagcaatc aaaaagttag aaagtattaa agcgatagga
    67921 aatgatgcaa tagctgcttg ctataacgag agtataaatt caggtattac gttaatgaaa
    67981 aaaatagacg aaccgcagaa accagttatt ccacaactcg tggccggttg gcttgagaaa
    68041 tctacggacc cttttacaaa agctgaaaaa atagcgtatt taatcaaatc taaagatggt
    68101 gattcatatt atttctgtga ttggtttgta cgagatggca tagtgacgca agagcaagga
    68161 gaagaattac tcgcttgggc aacaagacaa tcatatgaaa cactattgag cctatacaac
    68221 ggctacgagg ttgagaaaga gccgttatgg gcaataaaga atgccgatgg aaactatctt
    68281 actaaatgtg ctttatgggg aaaagatgga gtaaattata gttttgaatg caatccatct
    68341 catcgattgc ttttcactga taaagcaaca gcggatgctg cagcattgtt ggtgaatgga
    68401 acagtggaag aggtggtaga aagatgaaac taaaagacgg attttacgct agcagtcacg
    68461 gtatcggcgg tttaatgcta gatatgccga caaagaaccc taaaacacgc aagaaatcaa
    68521 aattcaaagt cggtgacatg gtccgctgtg aagcagaaga gttcgtttat ccgttcagag
    68581 gatacgttaa aaagatactg tcaaactcag caatcattcg tattgaaaat acaatgaagt
    68641 gtgatcgttc gactgcaaaa cacaagcatt atttagctgt agcgagatta gttgacatgg
    68701 aagtaatcaa gagcaaataa aaaaagccgg atcgctccga ctgattcaat aaatccaaca
    68761 catttattat atcacataaa ggagcggttt gacttgatgc aattgttacg agaggtagat
    68821 ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga actttcggcg tttggagcgg
    68881 atggcaggtc gctctttgat agatattaag tcgccgatta taacggatat gccgaaggca
    68941 ccgaagcatg gcaataaggc agaagacgcg attattcaga tgatggatat agaaacggag
    69001 agagatgcga ttctagcggc tttgatggct cttagtctga ttagtcgtca gatactctac
    69061 tacagcttct gtgtgccaga tagcttctca aactacagaa ttagccgtga agtgggttat
    69121 tcagaaagaa gtatacaacg gatgaagtcg gaagctctaa tagagtttgc agaagcatat
    69181 aaacacggaa aaataattgc ttataaataa tttggcggtt ttttggcgga atgatggcgg
    69241 tttttagaca tttaccagtg ttattatggt agtgtcgaaa gattaggaaa caggatcgac
    69301 aaaataaacg aagggaggca atctccctca tcgttttaaa cttcttctta gatagacagc
    69361 aactaattat gaagaaaagg atgtgaattc aactcctcct aaattcttca tcggttgctg
    69421 tttattttga ttagacagca gcactcacaa aactaaacat gttcttgtcg tctttcaact
    69481 gctgctgtct attaatttat gtattggagg gaagaaaaat gaaattatca gtagaaggca
    69541 ctccagaaga aatacaagaa ttgctccaag ctattggtag tagcaaggag caaaaggtaa
    69601 gtgtttctaa ttcagatatt gacggtattt gcaattgttt aaacagagaa aaaatatcta
    69661 atccttacta agagaaaata tgttcgttaa tgaatttcca attttcctct gtagctctac
    69721 cttgataatt tttttgcagt tcacagatga ataaggaatc gttattatca agtactgtat
    69781 ttaatttttc acacatttga tttggattca aattagtttt aactaaccaa aaagattttt
    69841 gtagctttat atatgcccca aattctttta ttatttcaaa tactttatca tacttttgcc
    69901 ctgggttatt aagatcataa ctaatcatgt agggtttata catgttgtct tgcacatcct
    69961 tgttttatat ttcag
//
LOCUS       DAZKPE010000007        68239 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000007 DAZKPE010000000
VERSION     DAZKPE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.007"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            41..922
                     /locus_tag="ACG930_000526"
     CDS             41..922
                     /locus_tag="ACG930_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0517714.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            935..2545
                     /locus_tag="ACG930_000527"
     CDS             935..2545
                     /locus_tag="ACG930_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517715.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2622..3281)
                     /locus_tag="ACG930_000528"
     CDS             complement(2622..3281)
                     /locus_tag="ACG930_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0517716.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3564..4229)
                     /locus_tag="ACG930_000529"
     CDS             complement(3564..4229)
                     /locus_tag="ACG930_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFQ0517717.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4376..4981)
                     /gene="dhaL"
                     /locus_tag="ACG930_000530"
     CDS             complement(4376..4981)
                     /gene="dhaL"
                     /locus_tag="ACG930_000530"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFQ0517718.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(5009..6019)
                     /gene="dhaK"
                     /locus_tag="ACG930_000531"
     CDS             complement(5009..6019)
                     /gene="dhaK"
                     /locus_tag="ACG930_000531"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFQ0517719.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(5994..6389)
                     /gene="dhaM"
                     /locus_tag="ACG930_000532"
     CDS             complement(5994..6389)
                     /gene="dhaM"
                     /locus_tag="ACG930_000532"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFQ0517720.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6543..6863
                     /locus_tag="ACG930_000533"
     CDS             6543..6863
                     /locus_tag="ACG930_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFQ0517721.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(6975..7832)
                     /locus_tag="ACG930_000534"
     CDS             complement(6975..7832)
                     /locus_tag="ACG930_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0517722.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(7940..9244)
                     /locus_tag="ACG930_000535"
     CDS             complement(7940..9244)
                     /locus_tag="ACG930_000535"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0517723.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPELDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9241..9750)
                     /locus_tag="ACG930_000536"
     CDS             complement(9241..9750)
                     /locus_tag="ACG930_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517724.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(9925..12060)
                     /locus_tag="ACG930_000537"
     CDS             complement(9925..12060)
                     /locus_tag="ACG930_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFQ0517725.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12143..13798)
                     /locus_tag="ACG930_000538"
     CDS             complement(12143..13798)
                     /locus_tag="ACG930_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0517726.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13800..14114)
                     /locus_tag="ACG930_000539"
     CDS             complement(13800..14114)
                     /locus_tag="ACG930_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0517727.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14284..14544
                     /locus_tag="ACG930_000540"
     CDS             14284..14544
                     /locus_tag="ACG930_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFQ0517728.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14558..14872
                     /locus_tag="ACG930_000541"
     CDS             14558..14872
                     /locus_tag="ACG930_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFQ0517729.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15602..16156)
                     /locus_tag="ACG930_000542"
     CDS             complement(15602..16156)
                     /locus_tag="ACG930_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFQ0517730.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16282..18211)
                     /locus_tag="ACG930_000543"
                     /pseudo
     CDS             complement(16282..18211)
                     /locus_tag="ACG930_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18517..19233)
                     /locus_tag="ACG930_000544"
     CDS             complement(18517..19233)
                     /locus_tag="ACG930_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFQ0517731.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19234..21057)
                     /gene="glpO"
                     /locus_tag="ACG930_000545"
     CDS             complement(19234..21057)
                     /gene="glpO"
                     /locus_tag="ACG930_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFQ0517732.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21071..22567)
                     /gene="glpK"
                     /locus_tag="ACG930_000546"
     CDS             complement(21071..22567)
                     /gene="glpK"
                     /locus_tag="ACG930_000546"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFQ0517733.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22703..24163)
                     /locus_tag="ACG930_000547"
     CDS             complement(22703..24163)
                     /locus_tag="ACG930_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517734.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24153..25448)
                     /locus_tag="ACG930_000548"
     CDS             complement(24153..25448)
                     /locus_tag="ACG930_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0517735.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25780..26457)
                     /locus_tag="ACG930_000549"
     CDS             complement(25780..26457)
                     /locus_tag="ACG930_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFQ0517736.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26487..27578)
                     /locus_tag="ACG930_000550"
     CDS             complement(26487..27578)
                     /locus_tag="ACG930_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFQ0517737.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(27679..28113)
                     /locus_tag="ACG930_000551"
     CDS             complement(27679..28113)
                     /locus_tag="ACG930_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFQ0517738.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28697..30154)
                     /locus_tag="ACG930_000552"
     CDS             complement(28697..30154)
                     /locus_tag="ACG930_000552"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0517739.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30151..32046)
                     /locus_tag="ACG930_000553"
     CDS             complement(30151..32046)
                     /locus_tag="ACG930_000553"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0517740.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32104..33879)
                     /locus_tag="ACG930_000554"
     CDS             complement(32104..33879)
                     /locus_tag="ACG930_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFQ0517741.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(33929..35425)
                     /locus_tag="ACG930_000555"
     CDS             complement(33929..35425)
                     /locus_tag="ACG930_000555"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0517742.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35619..37241)
                     /locus_tag="ACG930_000556"
     CDS             complement(35619..37241)
                     /locus_tag="ACG930_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFQ0517743.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37569..38882)
                     /locus_tag="ACG930_000557"
     CDS             complement(37569..38882)
                     /locus_tag="ACG930_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFQ0517744.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39127..39351)
                     /locus_tag="ACG930_000558"
     CDS             complement(39127..39351)
                     /locus_tag="ACG930_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517745.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39371..39793)
                     /locus_tag="ACG930_000559"
     CDS             complement(39371..39793)
                     /locus_tag="ACG930_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0517746.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(39935..40645)
                     /locus_tag="ACG930_000560"
     CDS             complement(39935..40645)
                     /locus_tag="ACG930_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFQ0517747.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40663..41160)
                     /locus_tag="ACG930_000561"
     CDS             complement(40663..41160)
                     /locus_tag="ACG930_000561"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0517748.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41197..41649)
                     /locus_tag="ACG930_000562"
     CDS             complement(41197..41649)
                     /locus_tag="ACG930_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0517749.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41784..42389)
                     /locus_tag="ACG930_000563"
     CDS             complement(41784..42389)
                     /locus_tag="ACG930_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFQ0517750.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42839..43459)
                     /locus_tag="ACG930_000564"
     CDS             complement(42839..43459)
                     /locus_tag="ACG930_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0517751.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43461..44330)
                     /locus_tag="ACG930_000565"
     CDS             complement(43461..44330)
                     /locus_tag="ACG930_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFQ0517752.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44353..44760)
                     /locus_tag="ACG930_000566"
     CDS             complement(44353..44760)
                     /locus_tag="ACG930_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFQ0517753.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44779..46068)
                     /locus_tag="ACG930_000567"
     CDS             complement(44779..46068)
                     /locus_tag="ACG930_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0517754.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(46095..46397)
                     /locus_tag="ACG930_000568"
     CDS             complement(46095..46397)
                     /locus_tag="ACG930_000568"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0517755.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(46422..48515)
                     /locus_tag="ACG930_000569"
     CDS             complement(46422..48515)
                     /locus_tag="ACG930_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0517756.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(49004..49768)
                     /locus_tag="ACG930_000570"
     CDS             complement(49004..49768)
                     /locus_tag="ACG930_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFQ0517757.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(49879..50748)
                     /gene="mdcB"
                     /locus_tag="ACG930_000571"
     CDS             complement(49879..50748)
                     /gene="mdcB"
                     /locus_tag="ACG930_000571"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFQ0517758.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(50773..51849)
                     /locus_tag="ACG930_000572"
     CDS             complement(50773..51849)
                     /locus_tag="ACG930_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0517759.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(51873..52466)
                     /locus_tag="ACG930_000573"
     CDS             complement(51873..52466)
                     /locus_tag="ACG930_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFQ0517760.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(52470..54146)
                     /gene="mdcD"
                     /locus_tag="ACG930_000574"
     CDS             complement(52470..54146)
                     /gene="mdcD"
                     /locus_tag="ACG930_000574"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFQ0517761.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(54136..54435)
                     /locus_tag="ACG930_000575"
     CDS             complement(54136..54435)
                     /locus_tag="ACG930_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFQ0517762.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(54537..56183)
                     /gene="mdcA"
                     /locus_tag="ACG930_000576"
     CDS             complement(54537..56183)
                     /gene="mdcA"
                     /locus_tag="ACG930_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFQ0517763.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(56190..57101)
                     /locus_tag="ACG930_000577"
     CDS             complement(56190..57101)
                     /locus_tag="ACG930_000577"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFQ0517764.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            57221..58078
                     /locus_tag="ACG930_000578"
     CDS             57221..58078
                     /locus_tag="ACG930_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0517765.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSGMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(58265..58627)
                     /locus_tag="ACG930_000579"
     CDS             complement(58265..58627)
                     /locus_tag="ACG930_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFQ0517766.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(58816..58998)
                     /locus_tag="ACG930_000580"
     CDS             complement(58816..58998)
                     /locus_tag="ACG930_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517767.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            58973..60412
                     /locus_tag="ACG930_000581"
     CDS             58973..60412
                     /locus_tag="ACG930_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517768.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(60419..62971)
                     /locus_tag="ACG930_000582"
     CDS             complement(60419..62971)
                     /locus_tag="ACG930_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFQ0517769.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(63085..64416)
                     /locus_tag="ACG930_000583"
     CDS             complement(63085..64416)
                     /locus_tag="ACG930_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0517770.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(64382..65860)
                     /locus_tag="ACG930_000584"
     CDS             complement(64382..65860)
                     /locus_tag="ACG930_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0517771.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(66165..68000)
                     /gene="tdc"
                     /locus_tag="ACG930_000585"
     CDS             complement(66165..68000)
                     /gene="tdc"
                     /locus_tag="ACG930_000585"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFQ0517772.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        19409 a        14562 c        11676 g        22592 t
ORIGIN      
        1 ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt
       61 cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt
      121 acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat ccacgacgat
      181 tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga
      241 tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag gcgatatctc
      301 tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc ttcatggaaa
      361 agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa
      421 agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt
      481 tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt tgatggaaac
      541 gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc tactttcttc
      601 tcatattctc agtgaagtcg agcgactagc ggataaagtc gtgatcatac gcgaaggaac
      661 actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga ccatcactat
      721 agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg actttgtgca
      781 aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga ttttagctga
      841 agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg aggatttatt
      901 catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt cacgctggtc
      961 cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat ggctagtcgg
     1021 tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt ccggacaagg
     1081 attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac
     1141 tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg aaatgttgct
     1201 tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa
     1261 aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa
     1321 ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa tatcgatcag
     1381 ctgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt ggctttttgg
     1441 gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg ctgcacaact
     1501 gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg gactttacct
     1561 tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc ctttaggctg
     1621 gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt atttgttttt
     1681 gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag atttgaacac
     1741 cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg
     1801 tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca cttttggttt
     1861 gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag aaagtaacga
     1921 cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac
     1981 gatcatggta gtcttgattt gtctagctgc tattttacca attgctagca tcaatcgttt
     2041 atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa
     2101 ccaactttat tggaccaata tgttactagc tattctattt gctatattgg caatcctgat
     2161 tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga aagacatgga
     2221 tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag tgtttatcgg
     2281 aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt atatctactt
     2341 agcttactcc tttgcactca attactttgg cggaattttg gatttaccag aatggttttc
     2401 caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg atctttccgt
     2461 gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta ttggttatag
     2521 gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc tagcctccaa
     2581 atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc ttctaactgc
     2641 tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt ctcctctaat
     2701 aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc aagttctttc
     2761 attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc aagcagatag
     2821 acagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg ctgtactttt
     2881 gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata atgcagtaag
     2941 agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag tgcttcgcca
     3001 aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc gcccggctct
     3061 attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt catactgccg
     3121 gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc tcctttttcc
     3181 acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac taagtgattg
     3241 aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc tccttctaaa
     3301 cagctatttc taataaagaa acataacttc ccttattcca actgataatt ttcttttatc
     3361 atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct ttttgtccct
     3421 tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt ttttaaatat
     3481 ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt
     3541 tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt ttgatatagt
     3601 ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga
     3661 tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt caactcttct
     3721 tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag ttcatgttct
     3781 ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc tttcagtatc
     3841 gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg
     3901 tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg
     3961 tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc
     4021 gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag tgcagctgtc
     4081 tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt gatttgttca
     4141 atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac
     4201 aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat cttttgtatt
     4261 ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt
     4321 cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagttttat tgaacttaag
     4381 gttgattgat cacatctaaa agcgttgaaa ataaaatggc actagaagca gctcctgggt
     4441 cgatatgtcc gattgcacgc tctcctagat aggaagctcg tcctttttta gctaccaaga
     4501 ctttggtgtg ttcttttgcc tggtcaatga tttcttttgt taaattccct gccttcaatg
     4561 cctctgtgac tggcagccaa acatctaaca tcgttttatc gtcagcttct gcctttcctc
     4621 ggctttgaat acccgctgtt ccctgctcga tcacttcgcc taatttttct tgagaatcaa
     4681 tagaatcgac ctcttttgtc gctttcatca tgttcatgaa tgcagatccg tataacggac
     4741 cagaagcccc accgactttc gatatcatcg ccatagagaa tactttgaat gtatcgctga
     4801 ttgtttcagg atgatcggct tgaaaagctt cttcataagc tgaaacccct cttcccatgt
     4861 tatttccatg gtctccatcg ccaatcgggg tatctagatc actgagatat tgtttgttct
     4921 gattgattgc ctctgcaaat tgcgtgagcc attcttggat ttcttgaacg gttagtttca
     4981 tattatcacc cttttatctt gagatttttt accatgaaat cgtctgtaca ttgctttcta
     5041 aagaatcttt ccattgtgtc tccgtcaagt cgatcagtgt tagagaaaga ccttgcatat
     5101 ctagtgaggt cataaaatta ccgacttttc ggaaaactac attgacgcct ctttcttcca
     5161 acagagctaa aacatcattc atgaacacga actgttccat caaaggcgtc ccgcccattc
     5221 cgttgactag tacacctgct tcttttggta aattcgagta atcatctaaa atcttagtaa
     5281 caagttcctt tgccagtact ttagaaggct gcatcttttc tcgacgatag cctggctcac
     5341 cgtggatacc aacaccatac tcgatctcat cttctcctag ttcgaatcct ggtttcccta
     5401 cttctggtac agttgctgct cgaagcgcta gaccgatcgt cttagttgcc tgtacgacct
     5461 tttctcccag ttctttcaac tcagctaggg aagcaccgtt tcttgctgca tcgcccacga
     5521 ttttgtgtac aaggacagta cctgcaactc cgcgttttcc agcagtatac gtactatttt
     5581 caacggcgat atcatcatct acgatcacac tttctacttc aatatcgtcc atagcagcta
     5641 attcctttgc catatcgaag ttcaatgcat cccctgtata attcttaacg atcagcaaaa
     5701 ctccttttcc actatcggct tccttaatag ccgtctgaat ctgatctgga gttggagaag
     5761 taaacacatc accaagcacc gctgcactta acatcccttc ccctacaaac ccggcatggg
     5821 atggttcatg tccgcttcct ccaccagaaa ccaaaccaac ttgttccgct ttctgattct
     5881 tggctacaac acgggaagat tctacacgat gaacaagttc tggatagctt tttactaatc
     5941 cttccagcat ttcttcgaca atattgcttg gatcattcat gatttttttc aatttattcc
     6001 catcctttct ttccggcatt ttgtgcttct gttaagattt gctgagtatc atctgttata
     6061 ccggcagtga tggctgctgc aaaagctcct tccactaaag gcgcatccac cagatgataa
     6121 cgttgctgct gctcttcttc caacatgtct tttgccagtt ccgagttcaa taccgcgcta
     6181 ccgatatccg caaaaacaaa ataactagct gcatcgcttg attcattgac tgcttctacg
     6241 attttcatcg ggtctgatcc gatctcgcca tttattccgc cgagagaaaa aatttgcacc
     6301 tcttcggatt tttgcatctg ctcaatcatt tctttaatac catctgttac tttttgacta
     6361 tgagaaataa gcaaaatact ttttttcaca agaatcttcc tttcttttac atagttgcta
     6421 acgattggtt tcgctttcat taatgaacaa ttcaagtata taataaattt ctaattttgg
     6481 gaaaatatgt gtagtgcttc ttgaagtttg ttatacttta attaaaagag aggagtgatc
     6541 gaatgattac aacaacaacg aacagtgtag agggaaaagc cgtagtagct tataaaggga
     6601 tcgtttttgg tgaggtcatt actgggatcc atgcatttaa agacttggag gcggggttgc
     6661 gaaatatctt tggcggccgc tcaaaaagct atgaaaacga actaatgggt gcaagagaag
     6721 aagcacttgc cgaaatggcc gaacgtgcaa aagcattagg agctgatgcg atcattggcg
     6781 taaaaatgga ctatgaagta ttaggcagcg acaatggcat gctgatggtc acatgtagtg
     6841 gaacagctgt ctccacgaga taagtagggg acatctgttt taataactaa agagagatgg
     6901 gacatgtagt ggcactcaag aattagattt ttcagtctaa cttcgaggta ctctaccttc
     6961 ccatcctctc ttttttattt ctttttgcgg atgattccgt aagctgctgc gactaacaca
     7021 cccgcccctg ctaaggaata actgacagaa gctgtttttt catttgtttt tggcaaagtc
     7081 tgacttgttg atttggatgg ctctgtcgtt tgctgaactg tttctgtcgt gcttccagag
     7141 gtcactgatt tttctcctgc cgaatgcaaa atatctttta ttcgttggaa actagctgct
     7201 aagtcagctt tttttgcttc aaaatcatta gcaactgttt gtgcttcgct gatctttccg
     7261 tggattgctt gactggccgc tgtgatatcc gcttgagttt gacttagctt tccagaagct
     7321 gtttgagcaa cctgatttaa ttgctgattg aattcttttg cttgttggat cttcccgtca
     7381 agatctgttt ggacagcttc cgcttttgct ttcgcttcgg caagcttttt ctcaagttgt
     7441 gcacggtcat ttcccacttt atttttaaga tcagctaaat cttgatcgat tgctgcttgg
     7501 tcttctttca atttgttttt tgcagcttct aatgcttctt cgagttcttt tcttttattt
     7561 tccaagtctt gcaaatgatc gatttggtca gaagaggtag aactatttat tgatgtatct
     7621 tctgaagatg aaatcgtttc tcctgaatta tctgtcggta cattggaagt catttctgtt
     7681 tccgaggcac cgttttcagc accagaagag cttatggttg ttgaaggttc tgtttgagca
     7741 ggttcagaag tttccgcaaa agctgtctgt cccaataaga aaatactgga aacagcaatt
     7801 ggccagatta acggcttcat tctttttttc atcacttttc ccatccttac tactttttaa
     7861 ctaatttctt attataagca aaaatgtttg gaagaaccat aaacacaaca ggctgtttgt
     7921 ctaaaaaacg gtgcatcttt tatttttttg tacgttccgg gcttttccat gtcccgcttc
     7981 cataacctaa aatcgttttg actgctggaa tgaaagtcgt cacgatcgtt atcgcgttca
     8041 ctatccagaa caaaagcata tatagtggtg cgaaaagaag gtatttcaat tttcttcgtc
     8101 gatcatctac aatcagcgaa gctagcaact ggaaaaatcc tgcgaccatt tcaaagcaga
     8161 tgaacacaaa actgaatgta aaagtaatat aaatctgttc gtagtttcct tgatatacat
     8221 aatgcccgat taatccagca aaaagaacta cggaaataca aaagaatatt gaccagacaa
     8281 tactcaatgt ttgatcaatg aagatgatcg ttcttccaat atgtttaaaa ggatggagca
     8341 tcactttttt gaaattcgtc agccagactt ctgttccacc ttttgcccaa cgttttctgt
     8401 gtcgatatag catcttcaac gtcacaggta cttccatgaa aaagataatc tcaggagcaa
     8461 aaacagataa ccagtcattt aactgatgat cccaagcaat actgatgtct tctgtcgctc
     8521 gatcttgtct gaatccgccc acatcgatca aggcttcttt tcgatacatc gtatttgctc
     8581 cactgtacgc ataaagacca ccgaaaacag ctgactgtgt tcgtttaatg atgcccacga
     8641 tacttgagaa ttcaaccgtt tgagattttg caatcaattt ggtacgattt tggacatcca
     8701 tatttgcagt gaccgcagca atatgtcttg caccagggcg aatgaaataa ttcacatacc
     8761 taatcagtgc atctagctcc ggtaccgtgt ctgcatcatt gcttaaaatc aatttccctt
     8821 ttgcaaaggc aagtccgata ttaaacgcgt gggcttttcc tttatttttt tcgatccgaa
     8881 ccacacgaag attagcgtat tttttcatca gtctagctaa tatttctggt gtttggtccg
     8941 ttgaaccatc gtctgtcact aatacctcat agttgtgata attcaatttc gtcatcaaat
     9001 actcgattgt atattcgatc acaatttctt cattatgggc tggcaccatg atcgtgatga
     9061 acggttcgac actcaaggga acatctaccc attctttttg cttatgtttg tataaaaaca
     9121 cataacacca gacaccaata aaccatacaa atccgcctaa aatcggataa gaaacgagaa
     9181 aaaaatacat aatagacaaa caagtatcta agaataaatt acctgtatgg gtgattgaga
     9241 tcatttcagt tccaccccat tttctttata caaatctgca atgaatgtcg tatctagatt
     9301 tttctcttcg gagacagaat aaaaacggac cgtttctctc tcttcttttg ttccaaaacg
     9361 ttccgtatac acttcttcaa gtaattcttg tctttttttc aatttttcat cttcatattc
     9421 aaaagattta tttacttttt tgtatagatt tcgattgttc cacctagtca atacaaatga
     9481 ggtaatcagg aaactgaaaa aaatcaatac aaaaaagccg attaagaaat acagcatttt
     9541 cttttctgat aaaaaagcgt acaaggaaaa atccttggct ctttctggtc tcgttaatgg
     9601 gaaaaagacc catataaaag gaagaacaac gatcatccat cctaaaagag ccactaacgt
     9661 ttgccaaatc tttaaccagt aattaccttt tgaaaaatac ttatctttca ccaaaattga
     9721 tgcaacttct tctcttgtta cttttttcat atcctcacct cacgtttttt tgttacgacg
     9781 taggagttta ccatacattt catttctttt cacataaagt gttcctaaat ttttcctaag
     9841 aaaaagaaca aaacatttct catcagcaaa tgaaaaatat tttgttcttt ttatcagttg
     9901 ttctttttat tttttatctc ttaattatgt tgctctttcc aatacgacaa tgcttttcat
     9961 tcctctagat atcgccgtgt acatttgtct gcgtcttctt tgctcatctc catcgttttc
    10021 aaatggatat aagattacat gatcaaattc cagtcctttt gctagactca aaggaatgat
    10081 ttggcagttt tctaatccat atgaattttt tttaatcgat tcttgtagcg tttgggtttc
    10141 ctcttctgtt tgggtgataa ctgccgcttt ttctcctttt agagaaacca aaatctcagc
    10201 tagtattttc aacaattctt cagaggatcg aaaagagcgg tattcgggtt cttttccttg
    10261 cggtcggatc gatacgatgt cgatcttctc ttgatccaca gcataggttt tgaaaagctc
    10321 tgtgattgct ccgctagaac ggtaactatt tctaagatca taccgatgga tcggcagatg
    10381 gtagtcgtcg aaacaacgca taatatcagc aaaagtagtg gaagaattaa agattgcctg
    10441 attctcgtca cctactaaag taaagtgagt ttttggaaat aattcgatca atagacctaa
    10501 ttgtgccagg gtataatctt gtacttcatc aatcaataga tagcgaaatg ctggtacatt
    10561 taccttttca acaagtaaat gacgaatagc taatataatg actgcttcat caacagtacg
    10621 tgtgggttgc caagcataag ctgagccata tcgtttttca taaattcttt caaacaactg
    10681 atgctcatcc acccatgcca tttcttcgat ttgtctggtt atttttcgat attttttttg
    10741 taaaagtttc cttgcataag ctacaatact ttgttccgaa tcatcagaaa tcaatttacc
    10801 gaataattcc aactgcctat cttctgtcaa cgagagtacc tgattctgca cagcaggact
    10861 ttttgcttgt ttcaaaagat gattcttcca ttcgctcatc agtgcctttt tcgttgcttg
    10921 aagcctatcg atcaatttag gatgagcagg aactttctca tatatttttt cgatcgtttt
    10981 tttagaaagg actgtttttc catttttagt aagtccacgg ataaaattcg gatgatctaa
    11041 aaacaaagga tctgattgtt ttagattatc gataaacttt ttgctacgca aacgttctgt
    11101 ctgctccgat acattttctc ccgtgatacg tttgaaataa gcctcttcac cttctatttc
    11161 ctctgctgaa agctgtgaaa ccagctgtat gatggttaga ttcagtggat ttctttcacc
    11221 taatgatggt aggacattcg aaatatagtc gataaaccga tgattaggtg atagaatcag
    11281 caagtcatcg gatgtcatcg tatctcgata taaatagagc agatacgcaa tacgctgcat
    11341 gatagcagag gttttaccac ttcctgctac gccatttacc aagatatttt gacttttcac
    11401 atcccgaatg attgtgtttt gttccgattg gatcgtagca gtgatagcct tcatttcatt
    11461 ggtctcatct tggcctaaga cttctaataa tacgtcatct tgaatagcta cagacgtatc
    11521 aaaaaacttg accaaacgat ctctttccaa aagaaattgt cgtctttctt taataaccgt
    11581 atcgatttta ttttgacgaa ccgtataaga agatggacca atcatgttat tgtaaaaaag
    11641 ttcggcaatt ggtgaacgcc aatcataaac aagattttca tctgcatcat ctgtgaaatt
    11701 tgctgtaccg atataaaagg attcttttgg ctcattatcc agaaagtcta caacgacttt
    11761 tccaaagtag ggacttttca ataaacgttc gatctttgct agctgatttt ctgcgttttt
    11821 ctgtttgata ttcatctgat cgatttctct atttttcatt tcaatcatcg aaaaagtatc
    11881 caggttatct aagtaactgt caaaattcaa tcgaagctcg ccagccattt ctttcaacga
    11941 ctggtttcct tctatttttg ccgtatccat cgattcccgc agttcgtttt ttttatcaat
    12001 tagcttttga tacacgttct tcagatatgc ttcttctaac tgtttttgtg tgttgaccat
    12061 acacattctc ctcttttttt aaagtggtgg aaccgattag tttacctctt ttaagagtcg
    12121 aatgcaagct ttttaacgag tatcatttgt taggatatat cagttcttca ggtcggacag
    12181 tttgatataa agaaaatgca ccatcaaggt tttttacgtg gtagccagac tgcttcaaga
    12241 ttctttccgc tagatagcta cgtaatccgc tatgacagct gacgatatat tcttgttggc
    12301 tgtctaattc atttaatcgg tcccgaagtt cattcaaagg gatatgtttg gcttccttga
    12361 atttgccctt ttccaattct tctgctgttc gcacatctaa taaaattttt ccttttgcta
    12421 gttctgtcgg caattcatgc cattgtacgg tttcactaag cccttctgca atgttcattg
    12481 ctgcatatcc tagcatgttt actggatctt tggctgagcc aaatggcggt gcatacgtca
    12541 attctaattc cggtaaatcg aagatcgtca aatgcccttt gattgctgtt gctaaaatat
    12601 cgatccgttt atccacacct tttgccccaa caccttgtgc accataaatc tcgccagtct
    12661 ctggatggaa gatcaacttc agtaaaatat ctgttgcttc tggataatag cttgcatgat
    12721 cttttcctga tacatgaatg acttcaaaag acagttcgtt ttctttggct gttctttcac
    12781 ttaaaccggt ggatgcggca gtcattccaa acgttcgtat aattgctgtt ccaataccgc
    12841 cttgatttct tcgagaaatt ccggaaatcg tgtccgcaac ttgtctacct tgacgattgg
    12901 ctggtgaagc aagagaaata agtgcatctt ttccagtgat ttgctgtttt acaacgatag
    12961 catcccccac cgcataaata tcaggaatat tcgtttgata acgttcgtct actaggatac
    13021 ccccgcgtat gcctaattcg attccagcgg tcactgctag ctggttatca ggacgaacac
    13081 caatggataa aataactaaa tcagcaggga tggtacgccc atcatccagt cgcaatcgtt
    13141 tcccgtggtc ttcaaatcca gcgacagcat gagaagtaat cacttctact ccttgatgag
    13201 acaattcttt ttctataaaa gctgccattt cttcatccag tgttggaaga atatgtggtg
    13261 cttgttcgat caccatgact tctaaacctc ttctttttag gttttctgcc atttccaatc
    13321 cgatgaatcc tgcaccaacg atcacggcac gctttggctg tttttctaat gcatgcatca
    13381 ctttatcgat atctggtaca tttctaatag aaaaaacatt gtcggcttct gttatccctg
    13441 gaatcgatgg aacaactggt tttgcaccag gagataaaac caatgcatcg tactgttcaa
    13501 tgtgtttttg accctcatgt acgacttcta ccgttttgtt ttcgggaaag atggctgtca
    13561 cttcatgatt tggacgcaca tctaaacaaa aacgagcgga taatgattct ggcgtttgga
    13621 caagaagatt ttcccgttca ctgatttctc ccgaaagata ataaggcaag ccgcaatttg
    13681 caaaagaaac atacggtcct ttttcaaaaa caacgatttc tgcatcttcc attaatcggc
    13741 gaagccgtgt agcagcagac attccacctg ctacacctcc gacaataacg attttcatct
    13801 tatttccctc ctactgttcg atcaaaccat tgattcatgc caccacgtac attcactaca
    13861 tcataaccag atttctttaa ttctttagct gcttgtttac tcctcatccc tgattgacaa
    13921 atcacataga cggtcttttc tttgtctcca tcatatctgt ttatactttg taatggaaca
    13981 tttttagctc cttttatatg cccgccccgg tattctgcag gtgttctaac atcaagtaac
    14041 gctggatttt ccaaaagctt ttcctttaat tctgggactg ttatcgattt tattgattga
    14101 aatagcaaat tcattttctg cacctcattt acatttttat aaatacctca tggggtatat
    14161 taaacaggag ctttattaat atgtcaacca gaatgactct tcattttttt cactactttt
    14221 tatatttgca taaaataccg ataaggggta ttatctaatt ataaaaatag aggagaatgt
    14281 gttatggaga ttgataataa aaatatcctg aaccgtttga aacgtacaga gggacaaatt
    14341 cgtggtatcc aaaaaatgat cgaagacgaa aaagaatgta tggatgtcat cactcaatta
    14401 agcgctgttc gttctagtat tgatcgcgta atgggcatga tcgttgcaga taatctgaaa
    14461 aattgctttg agaaacctga tagtaatcca gaagaacaag cggctaaact agaacaagcg
    14521 atcaagatga ttattaaaaa gtaaaggaat gatttcaatg aaagtcgttt tccatattga
    14581 tgaattagaa aaatggtcag aaacagggaa aaacgtaaaa aacctgataa aagcttctcc
    14641 agaaacgacg attgtcgtat ctgtaaatgg catcgcgatt accggttatc tagactctgc
    14701 caatgcagaa ttcttagatt tgcaaggagt cgtttttcac gcttgcgcca atgctatgcg
    14761 tgctaatcat atttcagaaa gttctttacc tgaacaagta atcgttgtac cagcaggtgt
    14821 ccttgattta gttgaactgc aatcccaagg ttatgcttat atcaagcctt agtcagtaga
    14881 ggttgcgaca gaagtgatca gcttcaagaa atttcggctt atttttcgaa gaagctactt
    14941 ctggaaaacc gtgaatcaaa ggttgtgaaa acgctgtcct gcatcaagta ataagaacag
    15001 ccaaacaaaa atagcttctc atatttttcg tttggttggg cttattaccg cagatgcaag
    15061 cttttgaaca ccgtttaagg aagaggttgt gaaatcagcg gtttgaccta agtattagag
    15121 aaaaaaacgg gaaaatagct cctcatattt tgccgttttt tgagctaata ccgaaggtca
    15181 gctgattgaa caccgtttaa ggaagagatt gtgaaaaagt cgcttagttt cgagtattaa
    15241 gaaaaatttt gtgaaaatgg atttctacat ttttgcataa atttggctta ataccgagaa
    15301 actggctttt gaataccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat
    15361 tagagaaaca aacggaaaaa tagctgctca tattttgccg ttttttgagc taataccgaa
    15421 ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctaccattta actccgaatc
    15481 acaagaaata atttcaaaaa caacttctcc tgtttttggt tcggttggct tattatcgag
    15541 aagtagctac tgggagtcta tttatcaaaa aaaggaatgc gacataggtc acaccccttt
    15601 tttattttct ttgaaacatc tttcggtact cgacagcata caagacaaaa gattgtaaaa
    15661 gaccgtaagt gatgacggca aaaatgactc tcacccacag cgttggtaat tctgggaaaa
    15721 gcagcaaaag gatcatgcca acatagatga cagcagtcgc tactttgcca taccacttcg
    15781 ctccacttaa tttgatattt ttagatagcc cgattaatcc agctacaaac ataaagcctt
    15841 cttttatcaa gaatagacca aacaacagcc aaagccacgg tcgataccat gccatagaca
    15901 aaatcagaaa aagttgtgtc aatttatctg caaacggatc aagcaccttc cctaagtctg
    15961 ttacctgatt atatctccga gcaatgaccc cgtctagata atcagacaaa cctgagacaa
    16021 caatgaccgc tcctgctata taaaatgact gtctcagcac aaaataaaga taaatcggca
    16081 gcaaaaaaat acggaatatc gataaaagat tcggaatcgt ttgtatttct ttacgccagt
    16141 ctgtgcttaa tttcatttta tcgccctacc tcctcagcac tcttttcttt ttattttagc
    16201 ttacacgggg aataaaacca atgatttcac tgtttttatt tttctttaca gacactgata
    16261 ttatgagcta atttgagata atcacttgct gttttcatcg tttactcttc tttcttcctg
    16321 tcgtttgcgc atttctttta ctagtacttt atgagctttt tttgatcctc gctctaggtc
    16381 acgctgccgt ttacgtgttt tataatcgat aaacagactg tctaaatcgt aacctgtcgg
    16441 gtacagatct tctgctgaac gcaccagacg aacacgctga cgaggcacgt ggattatttt
    16501 tttgtctaaa tatacatcaa tcgtatcttc acctatatct tcataaacta acgcttcttt
    16561 ttggtattca ttgacaaata tccgatcacc ttttgcaaag agctgacgtt cttttttatt
    16621 ctccttccta tttgtaactg ctgtcttagg aagaaattct tttttctgtg tccgataggc
    16681 tttttccgcc aagtaacgct ctgcttgatg gatcaatttc atcgacatat ccattttatg
    16741 agcaatccac aaagcttggc tttctcctgt ttcttccaac ccgcaactga tatttaggac
    16801 gaagtgcttc ccgatcgaaa gccatagcag ccggcacaaa atcttcatga tctccggcga
    16861 atttcttgat ttctccataa tgggtcgtgg caatgatcaa tgccccttgc tcatacatag
    16921 attccatgat tgcgatcgct agtgcagccc cttcatttgg ctctgttcca ctgccaatct
    16981 catctaaaag taccaacgta ttccttttta tctttttcaa aatagcagcg atgttttgca
    17041 tatgaccaga aaatgtactc aacgcatttt ctaaattttg gtggtcaccg acatcgacga
    17101 aaatctcatc aaagacagca agctctgtcc cttcttttgc cggaacttgc ataccgaaca
    17161 tcgccatcaa agtcaataaa ccgactgtct tcaacacgac tgttttgcct ccggcatttg
    17221 ctccggtgat aatcaagcct cgatagtctt taccgatttc aacatccaat ggtaccgcat
    17281 gctcaggtaa aaatggatgt ctgccttgct tgataatgat atgttccgat ttattgattc
    17341 taggtgtgct tccattgatt tctcggctaa attttgcccg agcaaagatg atatctaaca
    17401 ccgtgatcgt ttcgatcaat aaatcgatca cttcttcgtt ttctgcgata gcaccagtca
    17461 atgccgccag gacttgatat tcttcactga tttcttcagc ttttaacaac tgatagtgtt
    17521 cattcaattt agaaatcaca gttggttcaa taaaaaccgt cgttctttta tttgattcat
    17581 cgataatcgt tccatctatt ttatttttat agctggcttt gataggaatc gtatagtatt
    17641 cgcctttttg aacaatcatt gcttcttgga tcatttcttt gtttttcgga tgacgcaaga
    17701 atttcagtaa ttttgactgg atttcttttt cgattagttg taattgtttg cgtactttac
    17761 gcaaattacg tgacgcgtcg tcactgactt tattattttt tattttctgg tcaatcaact
    17821 cttctacatt tatcaaatca ggaagatgtt tgctataagc aaacaacaag ggtgtctggt
    17881 attgattctt atcaaaaaac tttgtgatca tccgactgct tctaagaaaa tccgcatatt
    17941 cgatcaaatc ggttggctgc agaatcaacc cttttttgac ttgttctgtc agtgcatcga
    18001 tcctcggcaa ccccataaat ggaacatgct gactgctttc taagatcaag cgtgcttctc
    18061 ttgtttcttc ttgacgatcc aagacagttt gtaggtttgt cgagaccgtc atatcgctga
    18121 ttcgtttttt gctatagttt ccaattgctc ttgcttggat ttcctttttg atccgatcaa
    18181 attgtaattg actaatcatt tcgttgtcca tattctctcc ttttcttgaa gagatacctg
    18241 tcccaaaata aataagggcc tagagataaa taaaaggata gaacacagct taaaaaagtc
    18301 atgtcctatc cttattagaa tacaaagata ttgttttcct gacaggtacc gtttcataag
    18361 cacaccaaat aaactttgtt tattggctat tcgacttact gattagatac cagctacact
    18421 cacaaaacat accccattct tctaggtctt atttattttc cacttaacta tagcaagaca
    18481 cattttggtt gtcaaacttt agtatgtttt atagatttac accattaatg aatagacacc
    18541 taccgcgata attgctccga tcattggacc tgcgattggt acccatgaat atgcccaatc
    18601 tgaagttcct ttattagcta ttggcaatac cgcatgtgct aatcgaggac caaagtcccg
    18661 agcagggttg attgcatatc ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa
    18721 tccacctaca gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa
    18781 cccaagaact aatacaaatg taccaattaa ttctgtgatc acatttgctg gataattccg
    18841 tatagcagga cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg ttgcattcca
    18901 atgtggcaaa taagaaagcc aaacaagaat ggcccctgca aaagctccta aaacttgcgc
    18961 aatgatgaaa ggaacgacaa gattccaact aattgcccct gtcatcgcca tagctagaga
    19021 gactgcagga ttcaaatgag ctgggcccat gaatccagaa atatagacag ccattgttac
    19081 agcgagtccc caaccaaatg cgatgacaat ccagccagaa gcctgtgctt tacttttgtt
    19141 taaattcaca gccgcacaca caccatctcc aagcaaaact aggatcagtg tcccaataaa
    19201 ctcccccatg atttgagtca tatcactgtt catttatttc tcccccttta gttcccgcag
    19261 atctgattct gcaatcaatg cttctaaacg tttagtctgt tgcgccttct cctcttctgt
    19321 ccattcaaaa tatccagcaa ttgcatcgat cacaggttgc ttgatctcat caagctgatc
    19381 tcgttcaaac aacagatgat ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat
    19441 ttcttcttct aaaccataac gtaaccgagc tgactcagcg agactcaaac caggataagg
    19501 tgccatttct tttgctaatt caaagatacg tcgggcatta gtcccgtaaa aatcagcgat
    19561 ataagtagca tcttcttcct ctaaaccggc tgctactcct tcttttgcta attctgtcac
    19621 tgtttcttct aatttagttg gatcgaagtt tccacctgaa atctgatatt ttttagagtc
    19681 gatttctttc gtctctattc cgtattcttc ttttaataat tggcgtatca atcgcaaagc
    19741 tccttctgcc atcttacggt aatcggtgat tttcccacca gataaagtca gcaaaccatc
    19801 tggttctctt tctaaagaac tacctctgga aatcgtagaa ggtgcttttt catcacggct
    19861 gttttccaaa tggttcaaca cgtcttctac ttcagcacga gaaactttgt tttccttata
    19921 ttcacttact gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc cattatctcc
    19981 accattgtaa tcagaaccag aattaccaat caacagtgga cgaagtcctg cccagcttgc
    20041 ttcgatatca ttcaatgtga tatttgcttc tggatagcga tgattgatca catccaatag
    20101 ataatctaca tcttcttgtg tgactttcgg atccgtaaaa tctccttggt aatccgtatc
    20161 tgtcgtacca aagtaagtct tgttttctct tggaatagca aaaaccatcc gcccatcttg
    20221 ctttcctgta tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat ctacaactaa
    20281 atggatccct ttagttggac gcattttagg agagactgga cgcgtaaaat tcaagtttcg
    20341 tactttatct acccaaggac cactcgtatt gatcactaat tttgctttga tttcgatcac
    20401 ttcatctgtc agcaggtcac gagctttgac gccaacgatt tgatcgccat catataaaaa
    20461 gccaaccgct ttcattttac ttactagata agccccatct tcggcagcct ttttgatatt
    20521 atcaatcact aaacgggcat cattgttgcg gaaatctaga tagacacccg cgccttttag
    20581 cccttctttt ttcaaaaacg gttctctttc caatacttct tctggtgtca gcgtataatt
    20641 ctcatatttg gttcctgtca catttgccag tttgtcataa aggtccattg ctactttgac
    20701 cgagaacata ttgaaggttg ttgctccttc gccctcatag attggcaaaa gcattggatc
    20761 tggttttggg atgtgtgggg caatactttg tacgactgca cgttcaccaa ctgtgtcagc
    20821 tactacttcc acatcaaatg tcttcagata acgaataccg ccatgaacaa gtttggtcga
    20881 gcgagaggaa gtcccttctg caaaatcctg catttcgatc aatcctgttt tgattcctga
    20941 tgctgctgac tggactgcca caccggcacc agtgattccg ccaccgatga tcaacagatc
    21001 caattcttct tgctgcattt tttgaatgct atcttgtctt gtcttgtttg aaaacatatg
    21061 gatttcctcc ttattcaaat gcttgggtag cttttactgc ttttttccaa ccgttgtaaa
    21121 gtttttctcg gcgctcttcc tccatttgaa cttcaaatag cttgccagct tcataaaatt
    21181 cgcggatctc gtctgtatct ttccaataac cgacagctaa tcctgctaaa aatgctgccc
    21241 ctagcgccgt tgtttccaag ttttctgctc gttggatcgg tacattcaag atatctgttt
    21301 ggaattgcat cagatattca ttgtttgctg caccgccatc tactttcaat acaggaatct
    21361 tgattccagt gtcatcttgc atcgtatcga tgatatctct cacttgataa gcaatcgact
    21421 gtaaagtagc tttaatgata tcttcttttg tcgtaccacg tgtcaagcca aacatagccc
    21481 ctcgtgctgc ctgatcccaa taaggagcac ctagcccaac gaatgcagga acaacataaa
    21541 cctcatcttc gcttgtagag cgtttcgctg cgtcttctga atcgctagct ttttgcaaca
    21601 tttgaagtcc atctctcagc cattgaatcg aagaaccagc cacaaaaata cttccttcta
    21661 aagcatagta aacctttcca tttatgccgt aaccaattgt cgtcaataaa ttatttttgg
    21721 ataattgcgg tttttcaccg gtattcatga caataaatga acctgtacca taagtattct
    21781 tgaccatgcc tggttcgaat gccatttgtc cgaataatgc ggcttgctgg tctcctgcca
    21841 tccctgaaat tggtgcttcg cttccataaa aatgataacc ttgcgtataa ccataaactt
    21901 ctgagttaga agtgactttt ggtaacatca ctcgaggaat atttagtaaa tctaaaatct
    21961 cctgatccca atctagctga tggatattga acaacatcgt ccgactggca ttcgagtaat
    22021 cagtaacatg tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg atcgttccaa
    22081 acatcaattc gcctttttca gctcgttctt gcgcgccttc tacatgatca agaatccagc
    22141 gtatcttcgt tgctgagaaa taggcatcga tcactaaccc tgttttttcg tggaaaaatt
    22201 cttgatagcc ttcatttttt aagttatctg caattccagc tgactgtctg gattgccaaa
    22261 caactgcatg atagattgga cgtcctgtat ctttttccca tattactgtt gtttcacgct
    22321 ggttcgttat gccaatccca gcaatctgat ttggtttgat ccctgattcg atgaacgctc
    22381 cggcaataac tgactgtaca gaattccaga tttcatttgc atcatgttcc acccaacttt
    22441 cttgcgggaa atattgcgtg aactcttttt gagaactgcc gatgtgtctt cctttcttgt
    22501 caaagataat tgctcgtgag ctagttgtac cttggtcaat cgccatgata tacgttgatt
    22561 ctgtcattgt gattccctcc attatatgca aacgctttct ttaactactc ttatcatact
    22621 actgttttaa aaaaagaaac tgtcaaaatt ttattctttt tttctttttt tgacagtttt
    22681 ttattatgaa gctatttttt aatcaattct tttctttttt cagcgtctct attcttcttt
    22741 tcaatcgaat aatgtcgtaa ggtgacgcaa attctgacag ataatattca cactgttttt
    22801 tgtttctctg gcaaaatgtg atcaccaaat catattcttt accttcttca taacttccaa
    22861 tctcaatacc gccgattccc ctcagttctc tgatcagata ttgttgaaaa gcaatacgat
    22921 aaatcggcag actttctaaa tcgattccaa tcactactgg ttttgcaata taaaaatcga
    22981 tcatcaaaag aacattggca tactggatca tcaggtaact aagctcacta tcttcagctc
    23041 ttttcctcgg caattgctgc accgctgttt cctgtaattt cgccagtaac tgtgttaagg
    23101 aatgcccgag cattttctgc tgctgttcca aaagccgatc acgctcatag acttcgatct
    23161 ttccaacaaa gaaaaaccat tcattgttga tctgggaaat ttggtagcct actgcctttt
    23221 cttctttgat tttcaaacga cgaggacgat aatgccataa catcgtttcc cgaatgtaag
    23281 tatctaaaac agcggttggt aactttttgc tccgtgtcaa atcatactga taaaatattt
    23341 cttcgtctac tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat
    23401 tcagttctgc tgctgttcga ctaagatgca tcacgatgat tggatcgatt gcttgataaa
    23461 gccggtccga ctgatagagt aatttctttt ctttcaaagt tgcgtacgta cttttttcat
    23521 tcaatagtct ttttttcgta atcccgagcc agcaagcaat ctgtgcttct gctgatgccg
    23581 taaacgttgt ttctaataca cggtccaatc ctagaatgaa cggtcttttt tctggtgtat
    23641 tttgcaaaaa aagcggtcgc tgatcttccg ggatatattg gaatagttca taataaaaat
    23701 atcgtatctg tagctcttct ccgtataatt gaccgttttt gatttgtaat ccaaattcct
    23761 ctaagagctg gttcaattct ttgatctttc gaaaaacaga agactcactg atattaaacg
    23821 ctgtcgctaa tcgaacgatg gatacttgct gatgttctaa taaatagacg agcatcttaa
    23881 acttcaagct ttcctgcaat aaaaacaata gaattttttc caaacttaca tcttcgtcca
    23941 acacaagcag cgcctgatac tcatttcgct gtacttctac ttttttttcc atcattcggc
    24001 caatcaattc aatatcttcc aaatattgat caaacgaggc ttttgacagt tggacatgct
    24061 ctctcaaacc attgatagag gctgttcccc cttgcagaac aaggtttcgc aaaatcagga
    24121 tctgtaactg ctcttttctt tctaataatg cttcaatctt cataggcagt attcgccacc
    24181 tttgaccaca ccatatctgg cacacggtat tctggctgga aaaatagctc atgttcttct
    24241 aactgttcaa acgtccatcc ttcttctact gcaattgtca gttggtcaag aaggtggaac
    24301 atctcttttt tgctttggag ctgtgctcca agaatctttt tttcagaatc aaatagaaat
    24361 ttgagtttaa ctttgctttg atttattgct gtaagcttgt agtctacgta tcctgtttca
    24421 attttttggg gataaaaaat gctctcttct tctgtcaaac ctacgcttcc taagaaatag
    24481 ccaaaccact gattgccgac tggacgatag gttccctgat cctttgtctg tgagccacta
    24541 attgtcttgc tgacatttcg tgctgtacgg acagcgttat ttactagaga aacatacatt
    24601 ttttcatttg ttggacgaaa agttacttgg atcgcatcgc caatcgcata aacgtctttt
    24661 tgagacgttt gcaagtagtc atctacccag atcgttccat catcattcaa tgttaattgt
    24721 tcttcccaca tctgattgtc gggacgagaa tgattagcca gcaaaacaag atcatagttc
    24781 tcctttcttt tttccgtctc tacaatagcg gtttcatttt cggtcaaaga cacaacttgt
    24841 tcttctaaaa aaagtgaaag cccttgattt ttcatttcct ttactaacgg ttctgtcatt
    24901 tcaggatcta gataacgaaa aagaattgac tttcggcttt cgtaaagatg gatttgtttt
    24961 tttcttgatg ccaacccttc agctatttcg attcctgctt gtcctgcacc aataattgca
    25021 attttctttg cattcatgat cttttgctga agagccgtta cgttttgtat ctttttaact
    25081 gggtgaataa gcgttgattc tgcagaaata tttcgaaact tttgatttga accagtcgct
    25141 agaatcaaac gatcaaaatc caattttttt cctcctgcta aaacgacttt tttttctttc
    25201 aatcctatta ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt cagttcttct
    25261 ttcgtgatcc aagaaagttg tttttcactg gtaacctttc cttttaatat caaattgaac
    25321 ccgctgggaa tccatcctaa cttcgattgc ttttcaatca aatatatttc acttgttggc
    25381 atcaattggc gaagataaat agccgcatga atccctgcaa acgacccgcc gacaattaca
    25441 atgttcatct gcattcctct ttcttataag gtgttctact gctaacttct caatcagaaa
    25501 acacagtatt cataactcgc tttcaacctt atgatacata gcgatgcagc agaatcaacc
    25561 ctctccatca taccgtgttc taggtctgct tctcaataat gtactagtgg acctaattga
    25621 agagtatcat ttctgaagag atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg
    25681 ccttttacgt acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg agttttagcg
    25741 tgtgtaatgt aatagttaga atagacacat catttatttt taattcttta atgcttcaac
    25801 aactgcttcg cctaattgat gagcagattg aggattttgc cctgtaagaa gccgcccatc
    25861 aatttgaacc acttctgaaa aagctgctcc agactgatag tttgctcctt tttctttcaa
    25921 agcatcttct gctaagaatg gtacttcatt cgttgtacca tttgcttcct cttcttcatt
    25981 actgaaccca gtcactgtac gtccagctaa aatagatttt ccagactcat ctgtaactgg
    26041 caacaatcct acaacaccgt gacaaacagc tgagaccagc ccttcatttc gatagatttg
    26101 tgaagcgact ttcccaagat ctattgcttc tggaaaatcc cacattgttc cgtggccacc
    26161 agcataataa accgctgcat aatcatttgc atccacatca tcaggacgta aggtatttcc
    26221 caaggcccga tttctgaaat cttcatcttc ataataggcc caatcgattt catccatatt
    26281 caaaacactt tgcggttcta aaggtacata tccgccttta ggactgacaa aatctgcatc
    26341 gatcccattt tttactaata catcataaaa atgagtcagt tcacttaacc acaaacctgt
    26401 aggacgctcg atcttttcgt acttttctac atttgttaat acgatcaata ctttcatttt
    26461 cccatcctct ttctataaaa attgcgttat tgataacgtg ctttcaagaa attatataat
    26521 gggcttggca aataaagctc tttatatgct tcttcaaaag gtttcgttac aaattcatcc
    26581 tcacggtttt ccaataattt ctctgcccag tcaggatcga cgatcatttg ctgtccaatt
    26641 gctgcaagtt ctgcatattt caatacctgc tctacatctt cgcgattgcg gatcccaccg
    26701 acaccaacta aagggatctt tccttgaatc gtgttatgga ccacttcaag aatcgattta
    26761 tcgttgtatt tatcagaacg agctattcga tcatacatat ttaatgaaac atgcagataa
    26821 tctagttttg actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa acggatacct
    26881 ggtgtttcat attcttctgg tgagaaacga taccctacga tgaatggttt tttagcatat
    26941 tgttcaaccg ctgagaaaac cgttgttaat aattcttcaa taaaacgata acgattttcc
    27001 aagctaccgc cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc
    27061 aaatacgtat ttgctccatg caactcgatt ccatcaaatc ctgattcaat cgctctacgt
    27121 gtggctttgc caaatgcttg gattgtttca acgatttctt cttcactcat tgctcgtggt
    27181 gtttccgcat caggacgttt tgctgcaact gcacttgcag atacaggctg ttctccagat
    27241 aaagttgctc gacttgtcat tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct
    27301 tctccttgga ttgctttcgc tagctcactt aatcgaggaa tcatttcatc atgagcgatg
    27361 ctgagttcac ctggccagcc ttttccgata tcttggacat ttgcagcacc agtaataaca
    27421 gcaccaagac ctttagaacg ttgtttataa taagtgatct catcttcggt gatcactcca
    27481 ttgaaaaagc tgagttgtgt cgtcataggc gacagcatca atcggttctt caattgaact
    27541 cctgaaggta aagtaattga ttgatcaaat tgtgacattg tcattcctcc cataattcgc
    27601 tctgattaac ctatcgagaa tcatctatca ttaaaccact cgattagttg tacatgcaac
    27661 taatttgctt aaaaaatttt attttttttg taacttatct gttgcatcat tcattgtctg
    27721 ggctaattct ttacttgctt catttcccaa aactgctttg tatgactgat gaagttcttc
    27781 ccagctacca tcgacttcct tagcaaattg gcgtccttgt tctgtaagat aaactaatga
    27841 caagcgacct tcgctaactg ttttgacgta tcctttatat tctaattttt caacaaaacg
    27901 agcaatcgtt gatggggcgg aatagagcat ttgtgcaata tctttttgtg gtattccatc
    27961 tttttctttt aatatcaata aaataaaacc ataagttggt gccagacctg tccttctaaa
    28021 cgcttcatca gctaatttat tcaacatgcg atctagcttt ttcacgctaa agaaaagaca
    28081 ttcatctaac gctttttcaa ttggcttttc catttcatcc cctccattgg cgtacatatc
    28141 atagtatgat ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag
    28201 atttgaaaaa aagaagtagc catcttcaaa gaatttcggc ttgttttcga caaaactcct
    28261 tctggaacac cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa
    28321 attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc gaaaaactgg
    28381 cttttgaaca ccgtttatat cagaggttgt gaaaaagccg tcctgcatca agtaataaga
    28441 acagccaaac aaaaatagtt cctcatattt tgtcgttttt tgagctaatg ccgatggtca
    28501 gctgattgta caccgtttat tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag
    28561 gagcaatttc aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt gatcgaggag
    28621 ttggcaggag aatactgttt attcgtaaag aaggggctgt gacaagactt ttgtcacagt
    28681 cccttatttc cttttattat aggatttcgc catttgattg gatgacttgt ctgtaccaat
    28741 caaatgattt tttctttaac cgtttctttg tgccattccc ttcgtcatct tgatcaacat
    28801 agatatatcc ataacgtttt gacatttgtg aagtagaagc gctgacgata tcaatgcagc
    28861 cccacgacgt ataaccaaat aaatctactc catctttgat agcttccttc atctgctcaa
    28921 tatgctgctt caaatagtca atgcggtaat cgtcttgaac ggttccatct tcttctactt
    28981 tgtctatagc tccgagtccg ttttcagcta tgaacagtgg tttttgatac ctatcatata
    29041 attgattcaa agcaattctc aaacccttag gatcaatctg ccagccccat tcacttgatg
    29101 gaagatacgg atttttaatt cctccagtta ttaagtttcc ttggacccct tcccaatttt
    29161 ctggatgagc actgactgca ctagacatgt agtagctaaa agaaacaaaa tcaacagggt
    29221 aggctgctaa gatttcttca tcacctactt ctatttttaa gttgacacct ttttcttcaa
    29281 acattcgttg cgtatacgct ggataatatc ctcttgcttg aacatcacta aagaacaaag
    29341 aagttctttg ctgctcaatt gttttttgaa tatcatccgg atcacaagaa tacggaacaa
    29401 gaagctgata gctgatcata caaccgactt gtgaaccttt gataatttca tgacaagctt
    29461 ttgtagctaa agcacttgct ataaactgat ggtgtgcacc ttggtatttc gcttgttcca
    29521 aatggggatg gttttcttca attactccta cgctaacaaa agggtgatgt tttacacagt
    29581 tgatctcatt gaaagtcatc caatatttta ctttattttt atagcgtttg aatactgttt
    29641 cagcgaaacg aacgtaaaac tgaataagct ttcgattagg ccatccacca tattctgtaa
    29701 ccaaatataa cggcatttca taatgggaaa gagaaacgac tggctcaatc ccatatttta
    29761 gacattcgtc aaacacttga tcataaaaaa ataatcccgc ttcattgggt gtttcttcat
    29821 caccatgagg aaaaattctt gtccatgcga tagacatccg atagcattta aaacccattt
    29881 cagcaaataa acggatgtct tctttaaagt gatgatagaa atcatttccg tgtcttttag
    29941 gataataata cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat
    30001 gccattgatc tgtccatttt tctttaggta aatcgctgtc gaatgtatac acatcagaca
    30061 cagataatcc tttttcatct acatcccatg caccttcaca ttgattggcc gctgtcgctc
    30121 cgccccataa aaatccttct ggaaattttt tcatatcgat ccccctaaac ttgctagttt
    30181 tcttgtttga ttatttttct tatgactagt aatgatattt ttgaatctac tactatttgt
    30241 aacaataacc attgtggtcg gatcatatcc ctctttgatt aattcttgca aatctacttc
    30301 catcaataaa tcgcctttac gtactttttt tccatcagat actgcacttt gaaagtattt
    30361 gccatttaaa ttcactgtat caataccgat atggatcagt atctctgctc cttcttcact
    30421 gactacccca attgcatgtt tcgttggaaa aactgttgaa acttccccgt ttacagaact
    30481 gtagattttt ccgtccgttg gaatgatcgc aaacccttct cctaaagatc cactagcaaa
    30541 tgttggatcg tttacttcag ataaatcaat tatttcacct gctgcaggag tacttaacac
    30601 tatatccttt gaggattctt cttcgatttc atccttgtag ccgaaaagaa aagttagcat
    30661 acaggaactg atcatcgcta agaaataact agcaactagc caaacaaatc cttcaccaat
    30721 ataaatcggg aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc
    30781 accagctact ccaccaaata tagctccaca tatacaagca atgtaaaatg gtcgtttata
    30841 tttaagagtc acaccataaa cagcaggttc agtgattcca aataatgctg tgataaatgc
    30901 agataaagat aaacttttta ctttcttatt tttcgttttc aaaaataccc caagtactgc
    30961 tcctgcttgc gcagctacgg cagtcataca tgctggacct agcgtatcac gaccgtagaa
    31021 agaaagattg ttggtcatta ctggtacaag tccccaatgt aacccaaaaa tcactaacac
    31081 ttgccaaaat ccgccgataa cagcaccaga taaaacaggg ctaaagttat aaacagctaa
    31141 atatccagct gcaatcagct gacttgcata atctgcaatt ggacctacaa ctaataaaat
    31201 aattgggacc atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg
    31261 caagcttttg cgaatcttag gctcaatata agaaagaacc catacagcta aaattgctgg
    31321 aataaccgta cttgtatacc ttgctagaat cacgggcatc cctagaaatc gcaaggttat
    31381 gctatcacta tatgcactga caatcgtagg ataaacgaga gctgctgcaa taaccatagc
    31441 gatgaaacga tctgtattga acttttttgc agcagtatat gccaaaaata taggcaagaa
    31501 atagaaaaat gcatcagctg ctgcattcaa aatgatataa gttcctgatt cagtagttaa
    31561 taaattcaaa ctcgtacata aggcgagtac tcctttgatc aaaccacttc ctgccaagac
    31621 gcctaaagtc ggggcaaaaa cagcggcgat catgtctata aaagagttta aaatgccttt
    31681 tttctcagtt cctctctttc cactagatgc atcatcttct agtttcattt gtttggataa
    31741 tacgtcatac acttcattta ctgcatttcc tactacgact tgaaacattc ctccagcttc
    31801 gactacagtg atcacacctt ctagttgctc taccttctcc ttatctgcct tcttattatc
    31861 ttttagggta aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc
    31921 tccgacaaat cggacaatat ctttcgctaa ttgtgaatag tccattttta cttccccctt
    31981 gttaattaat gccgtagcaa tccttcttac aagataagta tagttcttag aaaacggttt
    32041 ctccattcaa ttagtacccc ttctaatagc gaacgaaact gtacaatagt gtgtatggtt
    32101 tacttagccg agcaaatcac tcactgcttg aaagaaaaca agtatatcgt ttctcttata
    32161 gtcaaaggag acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa gtggtatctc
    32221 aagctgatac tctgtgattt ttgtttctac ttggcttttg ataagacagc acaacaaagt
    32281 ctcggcattt aacggaagca taactaggtc agaactagga gagattagtt gctgaatgga
    32341 atctatcttt ttatggattt ttatttgatt ttcttctttg tagtaatgat caagcagttt
    32401 tgttttcttt ttttcttcaa ctatggtcag cttttcacgc aaaatctgat aaatctccca
    32461 agattcaaac tcatctagaa cactaggtag ataaatcaaa tcatcccact caaaaataag
    32521 ctcttgctca gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt gatttttgaa
    32581 aagatacact ggttctatcc ggcattcttt gatccacatg ttcatacttt gttgaatctg
    32641 tttttttagt gtattcaaaa tactaattgg ctggttacta acaatcagta tctccccttg
    32701 ttttcgaaaa ggattcaacg cttcggcaag atacaaaaca aaataagcgc tttcagctaa
    32761 attgggacgt aattgaaaat gtattgggaa gaaacgccga attaaataaa tttctaaagg
    32821 ataacgggag atgatctttt gtacaaaatg attcatggta ttatgtccgg catccatcct
    32881 cgttttcatt tgtttgatat gggttagcaa aaattctgtt tcatggaaca ataacgaaac
    32941 aggaagatct aaaaaacgaa taatcgtttg ctcaaatgct cttagattct tctctatttc
    33001 tttgtttttt tcatcattaa tcatcaaata atttaactct aatagtcgat tttcaattgc
    33061 ttgtttttct tgattggaaa aagaataggg tagttctgat gataactttt ttgtgagggt
    33121 ctctaccatc ggaataaata atgtatacct gtttgttttt tctaaaagtt cttctcttcg
    33181 aagaatggtc aaaacgagat accgagaaaa tcgtatgaag tcctctcctg aaacaatata
    33241 attatatgat ataagaacct cttttaatgt cttttggaca gtcggcatga tattggaaaa
    33301 aattgtactg atttgttgag gaaaccttgc gtgttggatc accgtttctg ttccaacaag
    33361 agataagaaa attctttttg aattttcttc agcaatgatt tttagtcctt ttgtcgacga
    33421 aacttccagt tctaatttag gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa
    33481 tgatacggct gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac tgacataccc
    33541 tttttgaaac aataagtacg tcacaatagt tgaagctcgg aaatccatgc tggaatagat
    33601 tttatgtttc gtcacctctt gtatgatttg ctgtttagtt tcagattcaa ttgattctaa
    33661 aaaataacct gaacgtttat ttgactggat aatgattttc ttctcgtaga tagcaagcat
    33721 atttttgatt tcagtttgga tcgttttctt gttggtacct aaagcttcag ctaattcttc
    33781 gcttgttatc caatgattct tatttcttaa tactacaaga atttggagtt gtcgtttatt
    33841 taagtccatt tgcttacacc tcctctttgt tataaacata caggaaaaac ctctcaaatg
    33901 acaatagtca cttgcagagg tttaaaaatc atttgaagaa agatctatat tcaaggtttt
    33961 taccattaga ctggataatt tgtttataat attcaaaact atcttttttc aatctcctaa
    34021 agcttccgct cccatcattt tgtctatcca cataaataaa gccatatcgc ttcctcattt
    34081 cccctgttcc tgccgatacg atatcgattg gtccccacca taagtaacca atgatttggc
    34141 aaccatcttt tattgcctca gcaatttcct gaagatgtat ttttagatac tcacaacgtt
    34201 ttggatcgtg gattcgattc aattcatctg gtgcttcatc tagtccaatg ccattttcaa
    34261 ctatgaataa tggtaattca taacggtctg tcaattcatt catgacataa cgaaacccta
    34321 gaggatcaat tggccaactc caaggttcgg gagatttttc cttcaaaaag ggattatcga
    34381 aaccatttgc tccgccagta tctacgcgca tttctgcttc ttttttatag acagcgctac
    34441 gataataact aaatgcaata taatctgccg tgttagcttg caagcactgt tcgtctccat
    34501 ctaacattac tggtgcacag tcttcttcct tccatgtcct gtaaatataa gctggataat
    34561 gccctcggca catgacatcg gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa
    34621 atacattctc tggatcacag tcatatgcat aagtcgctaa tgcagaaaag ctacacataa
    34681 tacccatctt agcatttgga tcgattttct ttaataattg agtagcacgg gcgttcgcta
    34741 gaaacatatg atgacaggct tgataaatca ctttttttgt tagtgtagca atgggttcaa
    34801 gtttatctct agcagggaat gtaaccaatc cagcagctgc ataaggcata cgaaaagcat
    34861 tattgatctc attaaaggtc atccaatatt tcactttccc ttggtagcgt tcaaagacgg
    34921 tctgcgcata aaattcaaaa aagtcgatta attttcgatt ttgccacccc ccatactctc
    34981 ctaccaatgc taagggggtt tcataatgac taagagtaat tactggctcg atatcatatc
    35041 gatttaatgt attgattagt ctgtcataaa atacgagacc agcctcattt ggcttctgtt
    35101 cgtctcctct tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta
    35161 actccttcag taaacgaata tcctcttcaa atcgatgata aaaatcaatc gcttcatgag
    35221 aaagataatg gagtgattcg tctaaagcaa tctcccaaat ctttttttct tcattccact
    35281 gaatactagg atgctggttc atgatcccga taagcgtatc tgtcacatta ggtaatttgc
    35341 cgtcttccaa ccatgcacct tcacattgat tagcagctac tgctccgccc cataaaaaat
    35401 tttctggaaa tatttcctga tccataacta tctctcctcg ctatcaacaa tttcttactt
    35461 gaagtatagc tcgattcatc aaaacaagat attctaacta tttcggcaga agagaagaaa
    35521 aaaattgaat gctactcttc atttttaata tttatatata acaaatacat aagacgatcc
    35581 ccgaaagaaa acactcgtta accatctaag caaacgattt attttacttc caacacaaat
    35641 gcttcataag gtcgtaaatc aactttgccg tctggtaact gtttcagagg ataatttgac
    35701 acaataaccc ttaaagcttc acgtggaata gtgaacgtct gcttttcact ggacatatta
    35761 caaataacga gccattgctg gtcttcatat atgcgagaat aggcaaagac atgctcaggc
    35821 gtcttttcca ctaattcata gtctccccag acgatgatgt catgttttct acgcaaatcg
    35881 atcaatttct tgtacatata aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg
    35941 atttctttat aatttggatt gactcgaagc catggaattc cagtagtaaa cccagcatgt
    36001 tcacgggcgt tccattgcat aggcgtccta gcattgtctc ttcctttcgc cttgattgat
    36061 tccaagattt cctcttttgt aaatccagaa gaaatccttt cgttatacat attgattgtc
    36121 tcaatatctt ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc taactcttct
    36181 ccttgataga tataaggggt gcctttcatc atatggagca agatagcaaa catcttggca
    36241 ctttcttttc gatacacatc gtcatttccc caacgagaaa caattcgcgg aagatcgtga
    36301 ttattccaaa ataaactatt ccatccttca tcacctaaag atgtttgcca tttggataat
    36361 acttttttca gttcagagat actcaagggt ttcaaatccc atttgtcttt gccttcttgc
    36421 tgatctaatc ctatgtgttc gaattggaag accatggata attcatttct tttaggattg
    36481 gaataaagtt tagcgatttc ggtagttgct ccccatgttt cgccaacagt catcagattt
    36541 ttgtcaccaa aagttgcttg attcatttcc tgaagatact catgcagttt aggtccatta
    36601 cttgtgattt ctttatccgg ttctttgcca atcatatcga tcacgtccat acgaaagccc
    36661 ccaatacctt tatcgatcca gaaattcatc atttgataaa tctcttggcg aacctgttta
    36721 tttttccaat tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt
    36781 ttttcatcca actgccaagc agaaccactg aatattgagc gcaatctatt aggctctttt
    36841 ccattgaccg gatcacgcca aatataatag tcccgataag gattttcttt atttttacgg
    36901 gcctcaatga accacggatg ttcatcagaa gtatgattca ccaccagatc catgatgata
    36961 cggatatttc ttttctttgc ttcttcaatc agttcttcca tttcttccat cgtaccgaat
    37021 tctgccatga ttgcttgata attactgata tcatacccat tgtcatcatt cggagactcg
    37081 tatactggag aaagccaaat tgcatcaata cctaaatacg ccagataatc caacctggaa
    37141 ataatccccc gcaaatctcc aataccatct tgatttgaat cttgaaaact tcttggatag
    37201 atttgataaa caactgaatg gtgccaccat ttttgttcca tgattttcct cctataaatg
    37261 gatgtttcta ttttttgctt aatcatttat tttagtctct ctcactaaaa attgtaacgc
    37321 tttcaaatag ctattgcacc ttgttatcgg taacagaata aaacaaaaaa acagctgagg
    37381 aaattccctc aactgttttt tgaaaggatt gatttatgca gggaagaatg ctgatttcac
    37441 aacttcttta taaacggtgt tcactcagct gtcccttggt attagctcaa aaaacggcaa
    37501 aatataagaa actatttttt cgtttttttc tctaatactc aggccagaac gctgatttca
    37561 caacctcttt atttcacatt caatatccac atgaatccca caaatacaaa gaacagacca
    37621 tacatgattg gagatacttc ttttcctctt ttagctgcta acatggtaat tggatagaag
    37681 ataaaaccta atgcaatccc atctgaaata ctataagtca aaggcatgcc gatcaagatc
    37741 aagaatgaag ggatcgcaat ctctaagttt ccccattcga tttgtcgcaa agattgtgcc
    37801 atcaatactc ctaccataat caatgctggt gcagttactt gtgaagtaac aactgatagt
    37861 aatggagaaa agaacaagcc taacaagaag aaaatccctg tagtaatagc tgtgatacct
    37921 gaacgtcctc caacggcgat accagctgat gattctacaa atgcaccaac aggagaagta
    37981 ccaaataagg aacccgcaag catagctgtt gaatcagaag ctaaagcttt ccctacacga
    38041 ggcatcttgt tgtctttcat gaaacctgct tggtttgcta atccaactaa agttcctgct
    38101 gtatcaaaga aagtcacaag caagaatgtc agcactacga cccacatttg aagagaattg
    38161 atgtccccta catgttttaa tgcaactaaa aatgttggtt tcaaacttgg tgctgcggca
    38221 acaatttcag aaggcattgg aatcaaacct gtgaccagac ctaaaatcgt tgtagctgcc
    38281 atcccgatga agatgccacc tggtacacgc cgaacaagca agatagcagt tacgactaat
    38341 ccaaaaatcg tcaaccaagt agaaccaacg ttgagtgatc ctaatcctac taatgtagat
    38401 tcattcgaaa cgatgatccc accttcgctc agaccaagga aagcgataaa tagaccgata
    38461 ccgccagaaa tcgcatattt caaatctgct gggatcgcat caatgatcat ttcccgcagc
    38521 ttgaagattg tgatcaaaat aaaaatcaaa gaagcaacga atacgccggc taatgctgtt
    38581 tcccatggaa tccccattcc taaacaaaca gaataagcaa aaaaagcatt gatcccaaga
    38641 gcaggtgccg ttccaattgg ataacgggct aataccccca ttaaaacaca gccgatcgca
    38701 ctggctaatg cagtcgcagt aaacactgct ccttcatcca ttccagaagc acctaataca
    38761 gttggattta caaataagat ataagccatt gagataaatg ttgtaaatcc tgccagtacc
    38821 tcacgtttta ccgtggtgtt caatttttct atttcgaagt aggaaagtat tttttccttc
    38881 atcttccatc cccctaaatc cgaacattat aaataaagtc cgttaaaatt tcgatttatt
    38941 aataaaacaa cgtgttttat catatactaa aacaaaacat aagtaaacaa aaaattcgga
    39001 ttttaagcaa aatccgaacg ttccatctga ttaaatccct ttatctcaaa gttcatgaac
    39061 attcactttg gattacaaga atttctttat tgtgttaata aagtttcttc attctagtct
    39121 caaaaatcaa tagtgtgatt tgattttacc atttcgtttc tgttcttctt tgatgaattc
    39181 ttttgtatcg acaggattca gattatttag tccgccaaaa cctgtatcga ccatttttcc
    39241 ccagcctttt gtcttctttt ttcctgattt gagattcttt gctcgaagct tctcactatg
    39301 ttttgctcgc cgatacttca aataaccttc taatcttccc attagatcca ctgtttttcc
    39361 tcctttttat tcaatcagac gactcagctt ttcctataac aaaataattg ccttcagggt
    39421 cagaaaaatt gaaagtcaag atgccattgt tatctgtgat ttctcctggt tcttccatgt
    39481 tctcgtagat agtttcaaat tcatccgtaa aaaatactaa agaaggcggt ggtcctaata
    39541 cctctggtga aaacttctgc acaaatactt ttgggaatac gcctaattct aattcttttg
    39601 agatgctgag tacaatactc ttaaattctt ctggcaattc gattgtttca gaaatttctg
    39661 caccaatttt ttctacaaag aatcggcaaa tcatctctac gtcattgaca taaagcatca
    39721 cacgtgtttt ttgtatcatc atttgaccct tctttctatt tgattttctt tcctgtctat
    39781 aaactgattc cattatatca cgaaagcgca aacaccttgt gtttgatact attcaagaaa
    39841 aataaagcaa tagtttctag gattgctttc ctccacaaac tttttttaca aaaaaaaaac
    39901 ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct gattcatctt
    39961 tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt tccttcaacg
    40021 cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca atgaccagca
    40081 ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag ttgagacagc
    40141 gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg
    40201 aatctgcacc taaaggcagg aatgattcgc caccttgggc ttttcctaaa tgcagatttc
    40261 ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag gaaatactat
    40321 tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt gcacgtttca
    40381 gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta aatgcctgac
    40441 gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa tttcttgctt
    40501 cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt gttacgtggt
    40561 tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact tcccagaaat
    40621 tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata attgcttgat
    40681 gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc tgtatttgat
    40741 aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa caccgagcca
    40801 aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta aaaatgtacc
    40861 gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta aaaaatgatc
    40921 agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg caggctcttg
    40981 atcgatactc actaggaaaa aatcggtttc tttatctttt agctcttctg taagtttttc
    41041 tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtgaattat cttttccaaa
    41101 tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg aaggcgtcat
    41161 ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt tattgccttt
    41221 tttgacaaaa ttccaatctt cgctaacatt cttgcatact ttatttaaaa gatattccaa
    41281 ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt agttgttttc
    41341 tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt tcttgatttt
    41401 tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt tcttgattgc
    41461 tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt ggatgattcc
    41521 aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat cgacttcttt
    41581 gaattcgata ttgctaatag aatctagcgc tcgggcaatc attccgatgt ctcgaaggat
    41641 ttcagccatt tcatcccacc tttattttgt ttgtaagact agttcacctc tttttgttgc
    41701 aaatgcaact attttcaata aaaaaatcaa gttctttttt aataactagt aaagtatatt
    41761 cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt ttctaaaata
    41821 agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc tatactaaaa
    41881 aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc gtggatcgca
    41941 caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg tttattcgta
    42001 tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc atagacttct
    42061 ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg aagtgaccat
    42121 tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat ataggcacga
    42181 acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt tatttcttcg
    42241 aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa
    42301 cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag tgcgagtagt
    42361 cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc aaatgtatga
    42421 ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa tgaaatctgc
    42481 aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc tctggggctg
    42541 tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccaccaa acgaaaaata
    42601 tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct ttttcacaac
    42661 ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    42721 acatgagaag ctgttttttt gaaattgctc cttgtgactc ggagctgaac gacaggctca
    42781 cgacctctcg gtaaacagcg ttcaaaagcc aatttttcga tattaagcca tttctttgtt
    42841 acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa tccacttgag
    42901 tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca tattttcggt
    42961 cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc gttcgatctt
    43021 ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga tctgattcac
    43081 gatcacgttt gtaccgacgt tgccataaca cttcaaagtc tgctgttagg cgaatcgtga
    43141 tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc ttatcactaa
    43201 aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca agtgctttgt
    43261 aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc
    43321 cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac atatctggaa
    43381 atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta ccagccagaa
    43441 gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc caagttcata
    43501 aacagtccaa tcttatgctt gacaatttct tttactgctt catttgctgg aatcacatta
    43561 tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac tttcgtccag
    43621 ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat caattcagga
    43681 taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc aactactgca
    43741 tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg tccatgattc
    43801 gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt cactgcgtct
    43861 tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc tgtaccgccg
    43921 attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc tactactgct
    43981 tttgtcttca ggatattttc tttgaaaggc agatgggacc catcatacat gacagaagta
    44041 tatccgctgt cgattgcttc tttgatatca tcaaagtctc gggcgtggtc taagtgcaag
    44101 actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa cacatgcatg
    44161 ccgatatatt tagcggtatc gacacttgtt tgaataatga tcggcgaacc catttctttt
    44221 gctgcgccta gcatagcagg aagcatttct aggttatgcg tattaaaagc tccaactgta
    44281 aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat cttttattgc
    44341 caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt gtcgcatctc
    44401 atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag cagcatctgc
    44461 acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg tctgtttatt
    44521 ttccaaactc ttttctaaat attggatggc ttgatcgttc acatacaatt cagaaaattt
    44581 aagtccaact tgttcataaa gtttcgctaa tttatgctta tcttgggtag tggaaatctc
    44641 ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg atagggcttt
    44701 ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa atccaaacat
    44761 cattttccct actttcaatt aaaatgcttt caaaactggg cttaagatcc aggcatataa
    44821 gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgttgaatc ccatcgaatt
    44881 aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag caataccgcc
    44941 aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg tccctccggc
    45001 aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa
    45061 catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacag catttgggct
    45121 ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta atttcatagc
    45181 tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag ctagcaatac
    45241 atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat agttttgatc
    45301 tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga tatatagcgg
    45361 gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat gtgtcggcaa
    45421 cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct tagcaacacc
    45481 ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt
    45541 gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac aagctccgat
    45601 aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc caaagactgt
    45661 cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact tccattttgt
    45721 gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg caatatctct
    45781 acctaaaccc aaatcattca ttgcttgacc attgatagat tcaatagaag ggatgatccc
    45841 ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc caacgatgat
    45901 gctcgaaccg gcactcaaca cttgaaatcc taggagtgtc tttaacgtgc cagagatgac
    45961 ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg caatggtgat
    46021 cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgcccatgt ttttaccctc
    46081 ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat tttttcttca
    46141 atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg atcaactgcg
    46201 aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg tttcatggaa
    46261 actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt gttcaaaaca
    46321 tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcaccgca tacgaataaa
    46381 atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc aactactgaa
    46441 aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc caacttctct
    46501 tcgttgttga tcaattcaat tagttctttc atgatgttca gatgcgagta ggagtctact
    46561 gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa atcgattggt
    46621 tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg tcgggcatgg
    46681 gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac tgcacgaatc
    46741 atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct agcagctagt
    46801 tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct gtccgtcaaa
    46861 atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt tgtttcgaat
    46921 aatttttcta acttgccata gatgattcga tctactcggc caccactttc tttcatgaca
    46981 tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa ccgctgtagt
    47041 tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt taaaatcgga
    47101 tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa aaccagattg
    47161 acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt aatctcgatc
    47221 tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat cccatggtta
    47281 cagacaacga ctgatttata aacataattc aagtctcgct tgattacact ggcgatcgtc
    47341 gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc aattacttct
    47401 tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt tgttcggatg
    47461 ttttctttca atggattcat gacttggata tgattcttga ttcttacaat cagtgcagcc
    47521 atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg tacgtgtgtc
    47581 tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac ccactcgatt
    47641 gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata atttctttct
    47701 acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag
    47761 ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc atgtttcctg
    47821 attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat atcatcttct
    47881 tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac caaaggaaaa
    47941 taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat aaagaagtcg
    48001 gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga tcgttctgaa
    48061 cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata actgaccagt
    48121 gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg aaattcttct
    48181 tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa
    48241 atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt ttctaatcga
    48301 gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt acggatctcc
    48361 ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg gatcgtccgc
    48421 tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg ggctgtcatg
    48481 attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa
    48541 gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa gtggaaagaa
    48601 agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa cgaaaaagac
    48661 atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg tgaaaaagct
    48721 gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt tttcgtttgg
    48781 ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagag gttgtgacag
    48841 agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca tattttacaa
    48901 aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga aaaaggagct
    48961 gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc agcataatcg
    49021 gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa taccatatct
    49081 gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct tttcgatcga
    49141 ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg tggatctgtc
    49201 gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca ccgtctgctt
    49261 tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa cagcttctgg
    49321 ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc ttttggattt
    49381 ccagaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat atctccgctt
    49441 tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc cctcctactg
    49501 acaaaacagc taatgcaaga aatcccgttt gctcataact agaaggacct gtacctggac
    49561 cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg cccccatatg
    49621 aacgaccacc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct ccaccatgac
    49681 cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc actaacaaaa
    49741 tgattgctaa ataattgatt tttttcattg tcttcctcgt tatcttttat tacaaaaaac
    49801 tatttttatg atagccttgc taaaaggaag agtcaataac cagatgcata aactgttttt
    49861 ttagcaattt tgtcttattt agtcattgag taacatcgga caaatgtatg tgtcggcagt
    49921 ccataattcc tctatcttca gcatgaacaa gcttgcagac aagagatctg cgcttcctcc
    49981 aggagagatt tggttttcct gacaaaagtg caacagtgct gtaaatggac gatttggtaa
    50041 agcactttga ctagcagcat gagcaagttt ttgcatttcc actaacgttt tctgatcact
    50101 gcgatgcaat acgcatgtgt catctagcga actcatcaaa actaacaaca tatgcatttg
    50161 tttctgtaca tatgaatcat tatctagctc cttagctgct tgaattgcaa gcctgatatg
    50221 cggataccct aatatcgctt cttcatatgc accatttacg ccatattttt gcttcaccct
    50281 atgaccatga gtggtttttt tatgacgata ttttgtatca ggaaaagcag caagcttgct
    50341 gacatcatca agtattttcg ataaagaaaa aggctgttcc atactgattt tttgtgcaat
    50401 gacactgatc aatagcccca ttgcccaaat cgctccttta tgggtattga tgccatttgt
    50461 agcaatcagc attgcctttt ccgcttttcg cccaatctca gcaattcttt ctcttaactc
    50521 ctgatcaata gcatgatgcc atgctatttg agccatttct tcaaaaaaag gagttagcgt
    50581 cttagcagac ttaagaaata aagcatagtc catatcggaa tgtgcacccg catccagtgc
    50641 atccactaat ccaggttttg gacttaatgt tacttctgcg atcaatgctt cctctaccaa
    50701 cgcagcgagt tgctgagtca ctgctttttt tcgttcgtca tttatcatga cactcactcc
    50761 ttcttcctac tattacttgc tgaaaccttt tttgatagct acccaaatga tatgaagtaa
    50821 ccagcttaaa gcaaatgcac aacttgccgt cattagataa gctacaagaa tcatgactcc
    50881 tgaaggtaac tgcagccaac tatctttaaa caataataac agtacttgga aaacaaatac
    50941 attggctaaa tacgtacgat aagcataaac agacaaccat ttgaacaatg gcaattttgg
    51001 cgaatcgttt acaatcattt tggaagcgcc tatgaagaca gcaaagatga tgactaaact
    51061 gtataaactt tggatcgtat tcaagtaagg tgcattcgca aagctcaagt ctcctggatg
    51121 tgcgagcaat gaacggacag aaaagaacgc gataactaag gcaacaggta agaaaagata
    51181 acgtactctg tccaaatatt gatagacttt ttcgtgataa acaaatgcgg ctaccccata
    51241 aatcatgaaa ctagcaacaa accgatctaa taagtaccag ctgtcatgat aaggcccagt
    51301 caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg aaccaatcaa
    51361 tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa caaaaaacgg
    51421 catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg ctccatcacc
    51481 tgtgacatat ttcagtaaaa agcttgcagt atccgtatac ggagtttgtt gttggactgc
    51541 tggaaatagc caaagataag ccgtcgtcca tagaagatac ggaacgacta gttcaaaaaa
    51601 cttttctttc aaaaattccc aataagacaa atgctgactt gtttttacca tattataaac
    51661 aattgcaaaa ataaacattg gtgctgtgta tttaacgatg acgtaaaagg taccaagaaa
    51721 agctgtattt gttgcgctgt ggctgtttgc caaagcaaag ctcaatatcg tttgcatcat
    51781 aacagccgtt acagctgata ctttctggaa gtcacttacg ttgattttga tttttttgtt
    51841 ttcaaacatc tctttctctc tctttttctt tattaccaaa gttctttggt taatttaggt
    51901 ccttcgactg ttttcaatag aatttttttc tctggctctc tcaaatactc ttttagtgaa
    51961 aaaccgcctt gccgagtcac tacttgggta tcgaattgct caaaaaaagc aggatgcgat
    52021 tgaattacct gaattggcaa ttcaatcggt gaatttgcgt acagcagcaa atcaaaatca
    52081 ctggtttctt ttactgccgg aatcccagtc gataattcaa atcctaagct gccgccgatt
    52141 ccccatttac atcctgataa tatgtttcta gcagcatgaa attgctgata aacaggataa
    52201 tccatgattt tctcttgtct atacgattct tgttcgatga tgtcccacgg atgaatgact
    52261 tgtttgacgg catgttttga gatttctgtt gaccatctct gattgcgggc aggtccacgt
    52321 aaaccaatcg gtagtatttc tgcgtgatcc gtcgacgcac gacgaactgt tccgaacatc
    52381 ttttcagtta gaacgaccca ttcaggcaag gtgaaccctt ctatttcatg tttatcaaaa
    52441 aggacaatat catgtgcttg aatcattttt tatgcatccc attcttcgtc cattttggca
    52501 cggactttat ttgtttcgac acgtccgaat gttttggctg tttcgtttgt gtatcgattt
    52561 gtcagcatcg tgtcatttgt attgcggaca tcttgaatgg cttcattgat tgcttcgatg
    52621 actttgctga cattttgttc tgaagcagct tggtcggtga tatcttctag gaaatgatag
    52681 atcgctccta gttttgtata attattgata tcgtaagcga tagctggaac tttttcagca
    52741 gctgcttcga tttcagcaac cgaacgtttt gtcacacgtg cagcactttc tttagacatc
    52801 gcttggacgg taatttcttt attgtttaaa gcaatcaagc ggcttgattg taatccatgt
    52861 gctaaaaatg cacctgaaat agcatttcct gcaatcaatc caataactgg atgtccagct
    52921 tgacggagtt ttgcataagc agcagcacta ttagccaaag ccacatggat accgatcaat
    52981 tcttcgttat agccgtatgc ttggcttggt acatcgatca caacgatgat tggccgtttc
    53041 acttttttgt ctttatcttc ttcgtaaacg tgatccaaaa tttgtcccat gcggaaacct
    53101 tcaactaaac caacttcacc gtttcgtaca cggtacatcg ggtttttagg atcaggtacg
    53161 attgatgtca cgatggcttc ttctatgaat ttacttgatt taccataata cacagtacta
    53221 atagaagaag ttggattttt catgccagtt agtgccgcaa accaatcgta accaacactt
    53281 gctgcagctg gttcatttcc ttctgctact tctggtaagt caattgattt tgcttgatgg
    53341 ttagcaattg cttcattgta atcgtcaatg gccattggtt ttgaaagatc taaagaatca
    53401 agtaatgata aataaaatgc tgagctttca ctgcgatgcg tgtcttttcg ttcgtccatt
    53461 gctgcgatga cagcagcttt gattgcttct acactatcag tcactaattc atcaatgatt
    53521 tttgattcta cccgttgacg agatcctaat gtattccaaa tcaagtcttt gtcactagaa
    53581 tcaaattctc gaacgcctgc ttcttgttca ataacttctg gtccattcaa accgactctc
    53641 gctttttttg ttgcgattaa ataactcatt aatgctgaag taatcgacat accgccaaat
    53701 gatcctacac gtcctggaat caaaccgatg actggtacat attgttttag agcaatgatt
    53761 acatttccga tttctgaaat agataacagt ccgtagtttg cttcttgcaa acgaacacca
    53821 cctgtatcta gtacaatgac tggaaagatc tcatttcctt ttttattttc ttctaacaca
    53881 tgttcaagtg cagcaacgat ttttgcaccg gaaacttcac cgataccgcc accttggaat
    53941 tttccttcca tagcgattac tactgcttgt ttgccattga tcgtgccacg gctgacaacg
    54001 atcccgtcat cactttcagg gacgattcct tgtgctggta aacttggcgc gatgatttga
    54061 tcgaatggat caatcaattc acgtccattg tcaagtagag cgttcactcg ttctctggcg
    54121 tttaattcta caaaactatt tttcatctga aagttcctcc attgcttgcg tcaatcgtag
    54181 gtacacaact cctggtgtag caccgaagtc attgatcacg atatctgctg aaattggata
    54241 acgatcaaaa aatctcgtta atacattgtt ccatacttcg ccgaagccat cgcttcctgt
    54301 acaaattttt acagtagatt ctgttttttc tgttggaaac atcaagattt ccaaatctcc
    54361 tgaaccgacc actcctacat ggattttctt attgatcggc tgtttcgttg gatatttata
    54421 agctaattgt tccatggatc tctccccttt ttgtaaaaca gagcatacac gttctgctta
    54481 ttcgtctttc ttcttccatc tgggtaaatg gcgacaaaag gtttttctcg ccaattttat
    54541 gaccaagttc tgaatttcat tggtggttca tacaggccat ctgaccattc gatcaaatca
    54601 tcgatggttt gtgcagctaa taatgaacgt ttcgcttcac tacgtttgat gcctagatct
    54661 tctggtaatt tcacgatgcc ggctgcacgc aagctatcta gtgattcttt cgtgctagtc
    54721 attccaagag gtgtaacacc gccaattgct gcaattgctg cttgtcgttc ttcttttgtt
    54781 tttgctttgt acaaataagc aattccttct tctgtcacga tatgtgtagt atcttcgcta
    54841 taaatcatca ctggtgcatt ggctaagcct gcttgttttt gaacagctag tgcatctaat
    54901 tcttcgacaa agactggttt tttatttgaa ccatatgttt caaccatttg aacaactaat
    54961 ttttggcctt tccctaatgg atcatcattg tcgcgaagtg attgccatgc tggtgtagaa
    55021 tgacgacgac cgccaggatt atgtcccatg ttaggcgcac cgccaaaacc agataaacgt
    55081 ccttttgtta cggtagaaga gtttccttcg taatctaatt gcaaggttga accgataaac
    55141 atatcgatgg catattgtcc tgcagcttgt gataatgttc ggttactgcg catcgtgccg
    55201 tctttaccga caaaaaagac atctgggcga gcagcaatat atttttccat accaacttcg
    55261 ccaccaaaac tatggatgct ttcaacccaa cctgattcga tggctggaat catcgttgga
    55321 tgtgggttca atacccagtt cttcgcgatt ttccctttta accctagtga ttcaccataa
    55381 gttggcagta acaattcgat agctgctgta ttgaatccaa taccgtgatt caaagattgt
    55441 acgccgtgtt ctgcgtagat tcctttgatt gccatcattg ccattagaat ttgcaattct
    55501 gtgatgtttt gaggatctcg tgtgaataaa gcttctaatt gataaggttt atctgctttc
    55561 acgacaacgt ctacccagtc accagggata tctacacgtg gtaaagaatc gacaacttcg
    55621 ttaacttgaa cgatcacgat accatctttg aaagctgcag cttcgatgat tgttggtgtt
    55681 tcttccgtat tgaaacctgt gtacaagttg ccgtctttat ctgctttatc tgcagctact
    55741 aaaacaacat ttggaatcaa atcgatgaat aagcgtccat aaagttccaa ataagtatgg
    55801 atatcaccta atttcattgt gccgtcttca atcatttggg cgacacgcaa gctttgtgca
    55861 ccagcataag agaaatcgat cttgcttgcg attccttttt caaaaatatt caaatgttct
    55921 ggtcgtgaga tactagacat gatcaaatgc agatcattca ctttttctgc atctactttt
    55981 tcaagacttt ctgaaagaaa acttgcttgt ttttgattgt cgccttctaa tacaactttg
    56041 tcgccgggag caatcagttt ttccattact tctacgattt tttcagtttc tacatacttg
    56101 ccattgagca agttgctgat tttttccaat cgctgcgctt ttttttcgcg tttagaagcc
    56161 cagttgcggt ttggtttttc cataattagt catctccatt tttgatatag aaacgtggcg
    56221 tcatcaatac catgttggtc tagattgatc gtacggatcc ctttatctac accaaatttt
    56281 gtatgaatca gctttgtcaa agtattgccg gggggaaatt caatcgtcag atccattcct
    56341 aattcttttg ccaagtccat catttggttc cactgcacag ggaaagctag gttttccaac
    56401 aaatctttac gaatctcttc tgcgtcctga gtggctcttc catccgtatt ttttatatac
    56461 aaacatctag catcagatag atggacagac tgcatatacg gcttgaattt cttgaccgta
    56521 tcattcatca agagacagtg agatggcaca gggactttca gcagcttcgc tgtttgcgct
    56581 tggtgccgtt tggcttctgc caacgtaacg gataaacctt cgatactccc agataacgta
    56641 tgttgcatcg gacaattttc atttgacaga taaactggat ggtcaggatc aaatgttttt
    56701 gctacaattt cctcagcttc gcttctcgtc acacctacta ctacgcccat tgcataaccg
    56761 cttggataag cttctttcat taagactgcg cggtgataga ctagttccgc tgcattctca
    56821 aatctcaaag atcgacaagc aacagctgca caaaaagcac caatcgaatg tcctgctgca
    56881 atatcaggct gaataccgtt tttttccatt tcatctaaat aaaatactgc ttttgtcagt
    56941 aatgctagct ggataaaaac cgtatcttga tagttttctt ctttatcaac taaccgatac
    57001 cccgtcacat tttctaaacg ttccatgtac atttcaggga tatccgctaa catccctaac
    57061 ttctgactgc cttgtccagg aaataagaaa cctgtactca tgagcctcgc ctcctcagca
    57121 cttacttttt ccactgctat cttagtcaat ttctgctata ataaaaaatg ccaaaaaaag
    57181 aaaaaaccat aacaaaaagg tatggatggg atggataatt atgaaattgc ttcatctgca
    57241 gtattttaaa aaagtattcg aaacaaaaaa tgttacccaa gcagccaaag aattatttat
    57301 ttctcaacct gccttgagcc gtgcgatcaa acatttggaa aacgaattag gtgtcccttt
    57361 gttttaccat agcggcagaa acattgagac gaccgtttat gcagaagaat tttatccata
    57421 tgcagtcaag acattagaca cattagaaga aggaatcaaa ttattgtctt cggtcaatga
    57481 gaagatcgtt acttccgtca tattgtattt agaggtagcc tctgtttcta ttccgaactt
    57541 ggtccgaatt tttatggaaa agcatcctga tatccaatta acgatcatgc aacatcattt
    57601 accagatgat attaccgatc ctgtactgta catcacttcg gggatgaagc ctggcatgac
    57661 caatattcct atcatgaaag aacctgttta tgtcgccatt cctaagaaac atcctcttgc
    57721 taaaaaagaa catctgcaat tagaagatat ccaacgcacc cccatcttga tgctgtcaaa
    57781 gagcaacgcc ttccgtcata cactggatgc agcacttgaa gcgaaaagta tcgaattgac
    57841 gatcagttcg acgacagatg atcctgcgac attacgttct attgtcaagc aaggattagc
    57901 tgttagcttt ttcccaaaag tttcttggtc ttacgataaa aatgatcctt tcgtcttgcg
    57961 ggaaatcaaa gatttgccct tgacacgaac aatttattta tcttctagct tcacagaaga
    58021 tcatcctttg atcaaaatga ttgcaaaaac gatgcgggaa ttttatttag gaaaataaaa
    58081 aaaaaagagc tgggacaaaa ttcttgtcgc agctcttttt tcgaacaaac ggtgttccag
    58141 aagtaatttc ttagaaaata agccgaaatt tcccaaaaat ttgagaagca attttcgtaa
    58201 attccttctt atttcttgaa gctaaacatt tctgtcacaa cctcttctct attgtcctag
    58261 acattcattg cgttgattta aaacttccat caatcaaatc tgctagttca tctagctttt
    58321 ctattttacg tagatcaata gagatccaat gttctttatt catgtgatag gctggaaaat
    58381 acccctcttt tcctcgcaaa attccgccaa gttcaggatc gaccttcaaa tcaagaatat
    58441 tgatgatcct atggtcactt gcatcatcat agattttttc ttctggaaca gacatcagga
    58501 ccccaaacca ttttttgctt ttttgatgtc tgaatacgca ataatcagga aattttttaa
    58561 aaatatattc tggagacaaa ttgtatgttt cattgatgtg atcgattagt tcttttttcg
    58621 ttagcatctg cttccatctc tttcttattg attcgcttta ttcaaagata ccacgtaaga
    58681 atagaaaaat gaatacaagt agttgctaat caaatacttc gatatttttc ttttttatca
    58741 actcttaaat gttcaatccg cctgtgttgg tcttgctacc atctactatt aaaatgttta
    58801 ttattgtttg cccacctatt ttttgatttt agtggtatca tttttcaagt tcatgatgaa
    58861 attcttatca tcagtaaatg ctccagaaaa ataaacaatg attgaaaaat cagttgaaac
    58921 ttgaccaccg tttattttct ccgtattctt agaatagaag ggagtctgat tgatgtattc
    58981 actaatgaaa aaaatcatta ccgaaaaaga tattcgacgt catgtttctt tagtagaaca
    59041 attgctgaat catacaaaga taaccgtaaa tgaattagct gaaatcatag ggacaaccga
    59101 acgaacgatt ttttctgacc ttcaatctat tcgctctcag ctgcccgaag gctgggacat
    59161 catcagcgat caagcaggaa tcagtttgca aaaccagcaa aatttattaa caaatgacct
    59221 ttgggagatt tttttcaaac aatcagtcag tgtcgaactg ctgaaaaatc tgctttttac
    59281 aaaaaaagtt gctgtccctg attttctagc cgaccatggg ctttcttatg ggacattgaa
    59341 aagacatgtg actaaaatca atcagcgttt agcaagttac gacttgcaga tcgatttgac
    59401 gaaatataca gcttgtattc ttggaaaaga gcgtgcgatt cgtacttttt atcatcgatt
    59461 gctgattcct ttcactcata acaactattt tttcgaggat tattcgatcc atgaatccca
    59521 ttattttcaa tttttaagaa acctcagtca aactgaacta gcggttgaaa cagaagagat
    59581 tttcggaaca tgttggttct ttatcaatac gatccgtata aaagcgaatt gccgattaga
    59641 ttcttctatc cataccaaca gcacactctc ctccctgtat gactctgcat tgaaaaaatt
    59701 gtatttaacg gaaggtattt atcttaaaga cactgagctt tcttttgctt ctttctgctt
    59761 tctggaaagt tggaattaca acaataacta tggacaagaa accgctcgct gcctgcatca
    59821 ttctccattt ttagaggtcc tcgaaacgtt tgtagaggaa ctagcttcag agctgtctct
    59881 tgatcaacta aaaaaaacat ctctgactga taacttggct ctcctcatat taaaatatca
    59941 tgaatcgccg atattgattg aagcattgga ccgtcaatac catcgttttt tagaaacata
    60001 tgatcagcaa tatgcacact tgtatcaaca gaaagagaat ttactgaacg atctaaaaaa
    60061 agaaatagaa atcaatgaac caaattactt tctccaactc ttgtctctac tgatccaaca
    60121 aacgattttt tctatcaaac cgaatttgtt caatgtctat tttattttcc aaggagaacc
    60181 ttcatggaag gcgttcttgc agcaggaatt aaaagattac ttaggaaaac gtgtctgctt
    60241 cttacctatc gaactaaccg atctttccac tatttctttt gaaaaaacag atatcttgat
    60301 ttccaatttc cctctagatt ctctagatat ccctattgta tacatttctt ctattccaac
    60361 gaaaaatgag ctcaatcgtt tgactgaact cactttcaaa acttttttat agtaacggct
    60421 agcgactgta ttctctagct gttttttctt ttttgcgaaa cagtttgttc atgatccctt
    60481 tttctatttc tacaactaag aatagaagaa tcacatttgc tccaatcaat aactgttgtg
    60541 tcatcgttaa acttactgta ccgatcagct gctggccgac tggtagaaaa ataaccatcc
    60601 cttgcaataa agcaaggata cctaatgaaa gaaaaagcgc tttgttttgc aaaagacctt
    60661 ggttcaatga cggcttggac aactctctgc aattgatcat gtaaacagct tgagctaaga
    60721 cgatattttg cagaagaatg gtttgctgta agctttgccc ttcaaactgc atagccaata
    60781 aataggcagg aaccatgatc agtagggaga catagatgat ccgaaacaaa tgataaccag
    60841 ataggattcc ttgctttgga tctcttggtg ggcgcttcat gatttctgga tctggcgact
    60901 cgaaccctag tgcataagat aaagtgattg tcgttaccat attgacccat aaaatctgta
    60961 ctggggacaa aggtagcggg cgattcagca taagtgccca aatcaagatc aatccttgag
    61021 ctaatgcagt tggcaagaag aaattgatgg ttttttgcaa attatccaaa atccgccggc
    61081 cctcttttac ggcttttgca atcgtatgga aattatcatc tcctaaaacc atatcagctg
    61141 cctgtttgct tacttcacta cctttgattc ccatagcaat tcctacatcg gatcttttca
    61201 aagcaggtgc atcatttacg ccgtctccgg tcattccgac gatttctcca tttttctgca
    61261 aagctttaac aattcgcagt ttatgttctg gtgtcgttcg agcaaagaca tcgactattg
    61321 gcacttgctg aatcaactct tcatcagaca taagatccaa atcgatccct tctaaaactt
    61381 tggcagtatg ttttaagcca atttgttccg caatcgcttt tgctgtgtct ttgtgatccc
    61441 ctgtaatcat tttcactgag atccctgctt gttggcattc ctttacagct ttgactgcac
    61501 tttcttttgg cggatcgatc aatccggcga tccctgcaaa agttaattgg gttaaagtct
    61561 catgcgtgag ttcctgtttc gaatctactt ttttataagc aaatcctaaa acacgctgac
    61621 cttttctcgc aaattctgca gctgtctgac tccatgcttc ttgttctgca gaagaaagag
    61681 ttgatttagc aaataatact tctggtgcac ctttgacgta aatcaccgct cctttttcct
    61741 ccgcatgcat cgttgccata tatttgtatt cagaactgaa cggaatcttt gcttctattt
    61801 ttttcaaagg tagattggct gtttctgtgt gtcgaatcag cgcaacttct gtcggattgc
    61861 cacttaaatt ttctgttttc tgttcttctt ttgtttttaa ttcctgacag tttttcataa
    61921 tggacaacac gcaggcttct tcttttgcag ctacatccac aactgtcatt tcattttttg
    61981 tcaatgttcc tgtcttatct gaacagatca ctgtcataga acctaatgtt tctaccgaag
    62041 gaagtccttt gatgatcgcc ttttcttttg ccatttcatg tactccaacg gatagaatca
    62101 tggtcaaaac agctggcaat ccttcgggta ccattgacac caccaaagca atcgtagccg
    62161 aaagaagaat atgccaatcc ataccatatc gaaatgtcgt aaaaataact aagaataggc
    62221 tcaaacaaag aatgccttga aaaatttgtt tgtttaatcg gttgattttt ttaatcagag
    62281 gcgtcgtttg ttgttcgacc gattgcaatg cttgattgat tttaccgatt tctgtcgtgt
    62341 ttcctgtttc tacaacgaca ccgactgcag aaccagattg tacaagcgtt cctgaaaaac
    62401 ccatattttt ctggtcgccg atcgattctt cttctgtcaa aacggcatga cttttttcag
    62461 atgcttctga ttctcccgtc aaaatcgatt cttccactaa taaatcatgt gcttcgatta
    62521 atcggatatc tgctggaacg acatctccgg cacgtaagac aatgacatct ccttttacca
    62581 gttctttcgc agggattttt tcttgcatcc cgtttgatag tactatcgct tcttgtccca
    62641 tcagctgctt caaaccattc aatgattctt ccgcttttct ttcttgccag taactaacga
    62701 gtccattgac gatcactacg aataaaataa tacttccttc aatatattca ctagaagcaa
    62761 atttcaaaaa agaggcaatg atcaacacga tcatcagcag atcagtaaaa tgctttgcta
    62821 tttttttcca tcgttttgtc tgctgccttg cttttatttc attatatcct tgatcagtca
    62881 ggcgtttctg tcgttcttct tgcgacaagc cttctgttga tgtttgatag tttttcaata
    62941 catcttctac cgtcaatctg taccagttca tcctatcccc tcctgtttaa ttgatactgt
    63001 tattatacgc agggaagttt tttcaggcgt atcgattatt tcaggggggt ctgaaataat
    63061 tcgttttgca aaatgtatct gggcctaact gatatttcta ttgcttattc ttttatatac
    63121 aaaatttaag aatacaaacc agataaccaa taaaaaagga ataaagcgtg tcgtgctttc
    63181 gaataacaag ctgaaagcaa ttgaagtaaa aaacaccaac aaagcaagat ctttatatct
    63241 ttgtgtagtg ttccgtttct tttctttaat aaattgaaca tgtgcacaca agatcgaaga
    63301 ccacacaaat agaaaacaac tcgttgtcat gcctgccaaa agctgaaaaa acaatcgact
    63361 atcagctaca aaaaaatgta gacaaagacc ggcaaaaaat aacattcctg taattaaaat
    63421 accgtgtaaa ggtacgcctt tcttagaaag cgcacaaaac caatggggca aacttttttc
    63481 ttttgctgtt tgatataaaa tcctgctagt actgtagact gcactatttg ctgaggacaa
    63541 agaagcaacc aaaatcatta gattgacaat tgctgctccg ccttggcaat ggatcacttg
    63601 cagcatagtc actaaaggac tttcttttaa atctaaacaa tgccatggaa caacaaataa
    63661 aatcgacaaa atcgttccta tatagaaaaa gagaatacgc caaggcagac agttgattgc
    63721 ttttttcaaa ttcttttgcg gatcacttgt ctcgccaacg gttaagccga tcatttcaat
    63781 tccagcaaaa ctgaataaaa ccataggaaa tgagactacc attccagcaa agccaaacgg
    63841 tagtaattca tcgatctgtc caaaattttc tttgattccg atagactggg tatgaaaatc
    63901 tgagacactc aatcctatac ccaataagat aaaaaggaaa atccccaaga tcttgatgat
    63961 tgagaaaaaa gattccaatt caccaaacca cttgactgca acaaggttga ctgccattaa
    64021 gatcattagt gcgctacctc cgcttatcaa agctggtaca tgtacaaacc agaaatggat
    64081 atacaatcct attgctgtta attccgcaag tccagctcca agccagcaaa gccaataagt
    64141 ccaattgaca aaaaatgccc actttttgcc taaataatag tcaacgaaat cactgataga
    64201 gttaaatgta ctatttgcta aaaataaatc acccatggcc cgcatcaaac cataaatagc
    64261 caaaccgcat atcaaataaa cgagaataac agctggccct gctgatgcaa ttgcctttgc
    64321 tgaacctaaa aataatcctg ttccaattgc gccacctaat gcgattaact ggatatttcg
    64381 attagttaga gtccgtttca ttgccggttt ttccatcaag ttcacctttt tctttttcaa
    64441 gcagcatggc gacttcctgt tcccaagaag gtttctttat tttttcaata cagagtggta
    64501 ctacaaacaa aatgacactg atggctgtga ctgcaattag attgatccat gttccagctt
    64561 tcatcgtcag tccgacagaa aatccgattg ccgcaaataa aacaataacg acagtccaaa
    64621 ctccaagatt gctctttttc tctttttttc caattctaaa tggtcgattc aactttgcat
    64681 gtgtataacg caatctcaaa actgcgatcc ccatgatgac atagacgata cagtagataa
    64741 cagtagttga atttacgagc atcaaaaatg cttgattgac gccaggaatc agcaaataaa
    64801 aaagtgcaaa gattgagata atgacagact gagtcaaaat aacggatttg gatacgtcaa
    64861 attgattcgt cttccaaaaa ttgaattttg gtggatacgc accttttcta gcactttctg
    64921 tcactgtctt tgctggtcct gaggcccaag cagataattg gactgctaca ccaatgaaga
    64981 caagtaaact aaacagattc acaataagat gtggcaaacc aagaatttgg caataaatcg
    65041 aaatagattg cgcgatatta ttcaattcca tttgtccttt tggtacgaca tttgctacaa
    65101 ctaaagcatt caaaatattg acgaaaaata taaaaattaa cgcggcaaat actccgcgaa
    65161 tatacgtttt aactggattt tccaatcgag tgatatacac agaggacatt tcgataccag
    65221 taaaaataaa catgatcggc gcaaaataaa caaatgagga tgcagtcgta gtatctggta
    65281 ttaatttgtc ccatgaaaaa ctgcctaatg ttccggttgg tacgatccca actttgatcc
    65341 acgcagcaaa ccctaataag agcatcatcg tcaaaggcac gtacaatcct aaccaaacac
    65401 cgacttttcc gccgattttt gccatatcaa atttcaaatt caaaaaagtg atgatccaat
    65461 aaacgactaa aatgacaact aatgtaaatt tgctgttcaa accaagcggc acattatcga
    65521 taatattacc aaacaacgga gcgagtgctg aagcgaccat caccatccca ggaaacattt
    65581 ggacccataa cagccatgag acaacgaacc cccatttttt tcctagagca ttcgataccc
    65641 aaagttctgg accacctttt tggggaaaca ttccagcaaa ttcaccagag atcaatgaga
    65701 ttggaaaagc gtacaataat actgcaacca gcatgtaaaa aatcatcgtc cagctcgttg
    65761 ctgctacatc tggaatattt cgtacacttg ctacaagggc gcaggtcatt ccgataaagg
    65821 tcatggtcgt gatttgcttt gatgaaccag tatctttcat ctttattcct tctttcaata
    65881 gcgacatatg tttttgtttt cttttatttt tgttcaagaa cagaaatgac aaggtttcat
    65941 cgattcagta caaaacccag tatcaccgaa acatccattg aacgatctta gtgaactggg
    66001 tttgatacat gaaacgaacg atccaactta tagaacgttt tataaaaaag aatatcttgg
    66061 cgaggaatat atgaaaaaca gggggaaata caattgtttt gatgaagcaa ataattgtct
    66121 gttctccata tgtctcttgt tattctttca cacaaaaatc agttctattg gatgatttcg
    66181 tttagtttct tttccattgc tttggcgatt ttttttgtat aaaaattgaa aattcgatca
    66241 tcattcaaat aaggagtcat gatagccgca cgtagcagag tgattttctg ttcttttttc
    66301 cattcttctt tcgttagacc cattctttca acaaaacgaa tcggagaatc accgtaatct
    66361 tcttgtgtaa atgtagtatg agaagtaata aaccgttcac cataaacatc gccatccata
    66421 taagaagacc gatcgaacat tttttcattt aattcattga tagcgttcaa atctgtacag
    66481 ccttgttctt tgaataccca attgaccata ttaaaatcag gatgattcaa tggatagact
    66541 tcgattgttt ttcctttaac agtaaaagtc agatgatcga gaaattctct gaatctttga
    66601 gctgcctcga ttgaagcccc aatcaattga ccatatccgg tcacattcaa tggcaataca
    66661 cgatgtgctg tccagactgc ggcggcggtt gctccagctt ttgatccttc caaaatataa
    66721 gctcctaaca tatctggagc ctttactgat ttttcaaaca catatggcgc gaaataagaa
    66781 atgatatttc tcatattttt atgtttgatt acgattcctc cagcagcata agggacatag
    66841 cccatcttat gaggatctat cgtgacagaa tccgcttctg aaatagctct gaacccttca
    66901 tatacctctt tgtcaatcgt tacgcagtgg tggaaaacat gatgttcttc aaagaattca
    66961 gctaaggaag catacggcac aaattctcct gcttcgttta gaaacagtga acgcgcatag
    67021 ccgccatatg cggcatcaac atgtaaatag aaatagatcc cttcatcttt taacctttct
    67081 cttaattgga cgattttatc tacactgtct acttgacctt cttctgtcgt tcctacgaca
    67141 gcaaccacac ctagaattgg gattttttgt ccagctaatt cacgaattgt tttttccaaa
    67201 gcattaatat ccattcgata atcctcttga actgggatag caaccatctg atctaagccg
    67261 actccgcaaa tatctaacgc cttcatccaa gaatagtgtt ttgtttgagg gaccagccat
    67321 ttccctaatc tttggatatt ttttccgcta cgggaagaag ctgctttgac ctcatccatt
    67381 tcttcgtccg taaagctttc ggtcatttcc aaaatttctt caacagataa attcaaaagt
    67441 tcccactcag acattttttt cactttttca ggcagcactt ccttgacagc taaaggaatc
    67501 gatttgatgc aacgggcgta ccataatcct tcaagattag caatagaacc atctgctgca
    67561 atgtgtcccc atccgtctgt catattgaat aatgaagcaa aatcctgtcc tacttctgct
    67621 tccatttgcg aagttgccat agaagattcc aatgcaacat tatttgggtt ccacagcatc
    67681 gcatagttgt aagctaataa agcaggcatc aatgtttcag cattcatttg tccccagtaa
    67741 cggcctgctg aatgccatgg gatcgatcct gcgcgtaatc gctgactgac ttcatccaag
    67801 acctctatca tatggtcgcg ggtggctaga taatctggag tgagcttatc tccttcgcta
    67861 attgcaggca tatctgaagg aatataattt tctctccatc caagatgttc atctaccatc
    67921 ttgttcaaca acattttata aactggtcca ttttcagctt tgtcgcctat aaagacggcc
    67981 ttgatatcca tatctttcat ttttcttccc tccatatttt gttggtcaat gtcttgcaga
    68041 tacatgtgtt tatctgtaac acctcttcac tatagcgcca aaaatgagaa tttttttttt
    68101 ataacatcaa atccacgtag atttttacaa acaaaaataa ataaagtcgg atttttctga
    68161 taattcaacg caaaaaagcg aacaattttt caataaatca gtcttctaaa atagataacc
    68221 taaaaaaagc gaacaaaca
//
LOCUS       DAZKPE010000008        67948 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000008 DAZKPE010000000
VERSION     DAZKPE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.008"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..109
                     /locus_tag="ACG930_000586"
     CDS             <1..109
                     /locus_tag="ACG930_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0517773.1"
                     /translation="YIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            237..317
                     /locus_tag="ACG930_000587"
                     /pseudo
     CDS             237..317
                     /locus_tag="ACG930_000587"
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            324..1451
                     /locus_tag="ACG930_000588"
     CDS             324..1451
                     /locus_tag="ACG930_000588"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0517774.1"
                     /translation="MSREYYNRIEKGKQPLNDELREIIEKQIERFNPQEPLFLLIDYF
                     RVRFPTTDALAIIRDVLQLKSNYMLYEDYGKYGYESKYVLGDINIMCSMQEHLGVLLE
                     LKGKGCRQMECYLLAQERSWYDFMLDCMTAGGVMKRLDLAINDKAGILDIPKLKEKYK
                     AGECMSYFRMQKDYSGTEKCGSDLPKNTGETLYLGSTSSELYMCAYQKNYEQYVKNGT
                     EIEDTEIKNRFEIRMKNERAYYAVVDLLTYRDAERTAFSIINHYVRFVDREDDKPKSQ
                     WITNDDWAWFVGENREPIRLTTKPEPYTLQKALHWLQRQVAPTIKMVQALDRENRTTI
                     LKDMIEQAELKDKHKHLLQLEKSTIEERIDTAVPQENDGIF"
     gene            2440..2649
                     /locus_tag="ACG930_000589"
     CDS             2440..2649
                     /locus_tag="ACG930_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HFQ0517775.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            2761..4374
                     /locus_tag="ACG930_000590"
     CDS             2761..4374
                     /locus_tag="ACG930_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0517776.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGEISSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            4409..5620
                     /locus_tag="ACG930_000591"
                     /pseudo
     CDS             4409..5620
                     /locus_tag="ACG930_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            5643..6569
                     /gene="glsA"
                     /locus_tag="ACG930_000592"
     CDS             5643..6569
                     /gene="glsA"
                     /locus_tag="ACG930_000592"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFQ0517777.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6777..8237
                     /locus_tag="ACG930_000593"
     CDS             6777..8237
                     /locus_tag="ACG930_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517778.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            8458..10221
                     /locus_tag="ACG930_000594"
     CDS             8458..10221
                     /locus_tag="ACG930_000594"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFQ0517779.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            10305..10763
                     /locus_tag="ACG930_000595"
     CDS             10305..10763
                     /locus_tag="ACG930_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFQ0517780.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10872..11555
                     /locus_tag="ACG930_000596"
     CDS             10872..11555
                     /locus_tag="ACG930_000596"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0517781.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            11702..12316
                     /locus_tag="ACG930_000597"
     CDS             11702..12316
                     /locus_tag="ACG930_000597"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFQ0517782.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            12332..12538
                     /locus_tag="ACG930_000598"
     CDS             12332..12538
                     /locus_tag="ACG930_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517783.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      12763..12929
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            13103..14209
                     /locus_tag="ACG930_000599"
     CDS             13103..14209
                     /locus_tag="ACG930_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0517784.1"
                     /translation="MIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLSWSVIFLAR
                     SVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQFQPSELANL
                     FLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIAWVIFWAAA
                     VPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDSFIDSHGAG
                     YQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIGALCVLFLL
                     FSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGVPLPFVSYG
                     GTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            14301..15056
                     /locus_tag="ACG930_000600"
     CDS             14301..15056
                     /locus_tag="ACG930_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0517785.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15114..17153
                     /locus_tag="ACG930_000601"
     CDS             15114..17153
                     /locus_tag="ACG930_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFQ0517786.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQVTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKIRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(17262..18413)
                     /locus_tag="ACG930_000602"
     CDS             complement(17262..18413)
                     /locus_tag="ACG930_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0517787.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(18567..19097)
                     /locus_tag="ACG930_000603"
     CDS             complement(18567..19097)
                     /locus_tag="ACG930_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFQ0517788.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(19196..19546)
                     /locus_tag="ACG930_000604"
     CDS             complement(19196..19546)
                     /locus_tag="ACG930_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFQ0517789.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(19703..21232)
                     /gene="ahpF"
                     /locus_tag="ACG930_000605"
     CDS             complement(19703..21232)
                     /gene="ahpF"
                     /locus_tag="ACG930_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFQ0517790.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(21242..21805)
                     /gene="ahpC"
                     /locus_tag="ACG930_000606"
     CDS             complement(21242..21805)
                     /gene="ahpC"
                     /locus_tag="ACG930_000606"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFQ0517791.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(21949..22611)
                     /locus_tag="ACG930_000607"
     CDS             complement(21949..22611)
                     /locus_tag="ACG930_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0517792.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            22795..24441
                     /locus_tag="ACG930_000608"
     CDS             22795..24441
                     /locus_tag="ACG930_000608"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFQ0517793.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            24432..25514
                     /gene="uxuA"
                     /locus_tag="ACG930_000609"
     CDS             24432..25514
                     /gene="uxuA"
                     /locus_tag="ACG930_000609"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0517794.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(25622..27175)
                     /locus_tag="ACG930_000610"
                     /pseudo
     CDS             complement(25622..27175)
                     /locus_tag="ACG930_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            27323..28464
                     /locus_tag="ACG930_000611"
                     /pseudo
     CDS             27323..28464
                     /locus_tag="ACG930_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(28590..29669)
                     /locus_tag="ACG930_000612"
     CDS             complement(28590..29669)
                     /locus_tag="ACG930_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0517795.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(29772..30212)
                     /locus_tag="ACG930_000613"
     CDS             complement(29772..30212)
                     /locus_tag="ACG930_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0517796.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(30269..30679)
                     /locus_tag="ACG930_000614"
     CDS             complement(30269..30679)
                     /locus_tag="ACG930_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFQ0517797.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(30859..31293)
                     /locus_tag="ACG930_000615"
     CDS             complement(30859..31293)
                     /locus_tag="ACG930_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0517798.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(31393..32241)
                     /locus_tag="ACG930_000616"
     CDS             complement(31393..32241)
                     /locus_tag="ACG930_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0517799.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            32630..34396
                     /locus_tag="ACG930_000617"
     CDS             32630..34396
                     /locus_tag="ACG930_000617"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFQ0517800.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            34498..35757
                     /locus_tag="ACG930_000618"
     CDS             34498..35757
                     /locus_tag="ACG930_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0517801.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            35904..37205
                     /locus_tag="ACG930_000619"
     CDS             35904..37205
                     /locus_tag="ACG930_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517802.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            37208..38059
                     /locus_tag="ACG930_000620"
     CDS             37208..38059
                     /locus_tag="ACG930_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFQ0517803.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38072..38887
                     /locus_tag="ACG930_000621"
     CDS             38072..38887
                     /locus_tag="ACG930_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFQ0517804.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39038..40204
                     /locus_tag="ACG930_000622"
     CDS             39038..40204
                     /locus_tag="ACG930_000622"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0517805.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            40434..41081
                     /locus_tag="ACG930_000623"
     CDS             40434..41081
                     /locus_tag="ACG930_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFQ0517806.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            41165..42109
                     /locus_tag="ACG930_000624"
     CDS             41165..42109
                     /locus_tag="ACG930_000624"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFQ0517807.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTIQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            42244..43695
                     /locus_tag="ACG930_000625"
     CDS             42244..43695
                     /locus_tag="ACG930_000625"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFQ0517808.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            43716..44552
                     /locus_tag="ACG930_000626"
     CDS             43716..44552
                     /locus_tag="ACG930_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0517809.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            44552..45211
                     /locus_tag="ACG930_000627"
     CDS             44552..45211
                     /locus_tag="ACG930_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0517810.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            45337..46026
                     /locus_tag="ACG930_000628"
     CDS             45337..46026
                     /locus_tag="ACG930_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517811.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            46032..46988
                     /locus_tag="ACG930_000629"
     CDS             46032..46988
                     /locus_tag="ACG930_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFQ0517812.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            47032..47544
                     /locus_tag="ACG930_000630"
     CDS             47032..47544
                     /locus_tag="ACG930_000630"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0517813.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(47800..48348)
                     /locus_tag="ACG930_000631"
     CDS             complement(47800..48348)
                     /locus_tag="ACG930_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFQ0517814.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(48437..49618)
                     /locus_tag="ACG930_000632"
     CDS             complement(48437..49618)
                     /locus_tag="ACG930_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0517815.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(49854..51362)
                     /locus_tag="ACG930_000633"
     CDS             complement(49854..51362)
                     /locus_tag="ACG930_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFQ0517816.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            51521..51712
                     /locus_tag="ACG930_000634"
     CDS             51521..51712
                     /locus_tag="ACG930_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517817.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            51915..52832
                     /locus_tag="ACG930_000635"
     CDS             51915..52832
                     /locus_tag="ACG930_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFQ0517818.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            52825..53898
                     /locus_tag="ACG930_000636"
     CDS             52825..53898
                     /locus_tag="ACG930_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517819.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            54046..54564
                     /locus_tag="ACG930_000637"
     CDS             54046..54564
                     /locus_tag="ACG930_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517820.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            54545..54937
                     /locus_tag="ACG930_000638"
     CDS             54545..54937
                     /locus_tag="ACG930_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFQ0517821.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            55013..55948
                     /locus_tag="ACG930_000639"
     CDS             55013..55948
                     /locus_tag="ACG930_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0517822.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            56081..56860
                     /locus_tag="ACG930_000640"
     CDS             56081..56860
                     /locus_tag="ACG930_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFQ0517823.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            56853..57170
                     /locus_tag="ACG930_000641"
     CDS             56853..57170
                     /locus_tag="ACG930_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFQ0517824.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            57414..59024
                     /locus_tag="ACG930_000642"
     CDS             57414..59024
                     /locus_tag="ACG930_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0517825.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            59181..60029
                     /locus_tag="ACG930_000643"
     CDS             59181..60029
                     /locus_tag="ACG930_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0517826.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            60260..60739
                     /locus_tag="ACG930_000644"
     CDS             60260..60739
                     /locus_tag="ACG930_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFQ0517827.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            60772..63000
                     /locus_tag="ACG930_000645"
     CDS             60772..63000
                     /locus_tag="ACG930_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0517828.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            63129..64772
                     /locus_tag="ACG930_000646"
     CDS             63129..64772
                     /locus_tag="ACG930_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFQ0517829.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(64845..65390)
                     /locus_tag="ACG930_000647"
     CDS             complement(64845..65390)
                     /locus_tag="ACG930_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFQ0517830.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(65413..65898)
                     /locus_tag="ACG930_000648"
     CDS             complement(65413..65898)
                     /locus_tag="ACG930_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0517831.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(65888..66700)
                     /locus_tag="ACG930_000649"
     CDS             complement(65888..66700)
                     /locus_tag="ACG930_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFQ0517832.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(66839..>67948)
                     /locus_tag="ACG930_000650"
     CDS             complement(66839..>67948)
                     /locus_tag="ACG930_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFQ0517833.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        22706 a        12054 c        13354 g        19834 t
ORIGIN      
        1 gtatattcct ataaaagata ttatcctaca ctttgaaaaa tacgattatc gttttcattg
       61 gaatagtgat aattcagtta ttgaaatttg gatacctatt caagattaga agcaatttta
      121 tatccataca cacaaagcag ttagtcttag gattgactgc tttttctata cagattttta
      181 atgacaggca attatcaatt atggtagttg ccttttttga ttggaggaat tgaagaatga
      241 atgataaaaa ctttattgaa gaactaagac aaaagcgtga ggaatacgga gtaacacaaa
      301 caaggcttgc tgttgcctgt ggtatcagcc gtgaatatta caaccgcatt gaaaaaggaa
      361 aacagccatt gaatgacgaa ttaagagaaa tcatagaaaa acagattgag cgtttcaatc
      421 cgcaagaacc actattctta ttgattgatt actttcgtgt ccgctttcct actacggacg
      481 cattggcgat tatccgtgat gtattacaac tgaaatctaa ttacatgctt tatgaagatt
      541 atggaaaata cggatatgaa agcaaatatg tacttggcga catcaatatc atgtgttcca
      601 tgcaggagca tttaggtgtt ttattggaac tgaaaggcaa aggctgtcgg caaatggaat
      661 gttatctgct ggcacaggaa cgctcatggt atgacttcat gctggattgt atgacggctg
      721 gtggtgtgat gaaacggctt gatttggcta tcaatgataa agcaggaata ttggatattc
      781 caaagttaaa ggaaaaatac aaggctggcg aatgtatgtc ctacttccgt atgcagaaag
      841 attacagcgg tacagaaaaa tgcggtagcg atttaccaaa gaatacagga gaaaccttat
      901 atctcggttc aacaagtagc gaattatata tgtgtgctta tcagaaaaat tatgagcagt
      961 atgtcaagaa tggcacagaa attgaagata cggagattaa gaaccgtttt gaaatacgca
     1021 tgaagaacga acgagcctat tatgcggttg tagatttact gacctatcgg gacgctgaac
     1081 gcaccgcttt ttctatcatc aatcattatg tccgctttgt tgacagagag gacgacaagc
     1141 caaaaagtca atggataaca aatgatgatt gggcatggtt tgtaggggaa aacagagagc
     1201 cgatacgctt aaccacaaag ccagagcctt acactttaca aaaagcgttg cattggctac
     1261 aaagacaagt cgcaccaacc ataaaaatgg tacaggcatt agacagagaa aatcgtacaa
     1321 cgatactgaa agatatgatt gagcaggcag aactaaaaga caagcataaa catttattac
     1381 aattagagaa atcaaccata gaagaacgta tagataccgc tgttccacaa gagaatgacg
     1441 gtatttttta atgtaattga aaaatttcag atttagtcag caaagagctg ttttcattcc
     1501 ctatgtgaag tgaaagaaga aaaataaatt ttttattaaa tctgcaacaa aatggctact
     1561 tgcgtacaga tatggtgcga gaaaaggaaa tctaaacttt ttttgaaaat aggtcattaa
     1621 atcggggctt gctgtcccta tatgaagtga aagaagaaaa aagttttgaa aaaatgacgg
     1681 aaattcgtga ttagtggaca gtcttctgtg aaaagaggaa aaacatcatc attttgtatt
     1741 caaacaggca ttagcagttg agtgttgatg tgaaaagatg aaaatacttt gttctcaact
     1801 taacaattta aggtttccgt tccctatatg gtgcaaagaa aatatttcat tctattgttg
     1861 gcagtaacgg tatggtttgg gtagttaggg tgtgaaaagg aaaatattct tttttcatca
     1921 tcaacttagc aaaatgacat tttctatccc tatatggtgc atgaaaagaa gttaaaattt
     1981 ttccatttaa acttagcaaa tggacgtttg ctgtacagat agtagtgaaa aaggagaaaa
     2041 tcaaccgttg attgccaaaa tgaaccgttc catttgtact aataatggaa aaagttttgg
     2101 attttggtta cgtttctcct cttttccaac gcgatatata ggaaagacga tttttttctt
     2161 tcaatcgttc tttgacaact gaataaagct attcaatacg tttgacagac agctagccgt
     2221 tgaaacaaat acgccacgac ctttcccctg caagagcgag cgaaaaccta tttgtgttct
     2281 tgtaaaagat ttgtcctctt ttatcgccat gacctgtact gtcagataat gatactcccg
     2341 tacagccaca gcttgagcat taagagcgtc gcacgcaatg ggtacggcta cataagaact
     2401 atgcagaggt ggaactcctg tgggctatga caaaagccgt tgaattgctt agaaagattt
     2461 tacagaaagg gggtatgtgt tattgataat gctgtaaaaa caattcaaaa gaaaaatggc
     2521 aagtgtggca ttggcaacag aggaaagaca aagattgtag taaaagagca tttttccgaa
     2581 aagggcaaaa caatggaaga acttctaact gatgtcatgc tggaaaaagc aaagcagaca
     2641 atcgcataaa atcggtgcag ttgtaagaaa tagattgaat gacaaaaagt acccgtgtta
     2701 tactttactt gcaagcaggt attgtaaaca cgggttagtt ataaaggagg ataactgaca
     2761 atgaaacaac agatttacaa tactgcactt tatcttaggt taagccgaga tgatgaatta
     2821 cagggcgaaa tttccagcat taccacacag agaagtatgt tgcgtttata tgcaaaagaa
     2881 catcatttga atgtcattga tgaatatatt gatgacggct ggtcgggaac aaattttgac
     2941 agaccgagtt ttcaaagaat gattgaggat atagaggcag gaaaaatcaa ctgtgttgta
     3001 acgaaagacc tttcccgtct tggcagaaat tatattatga caggacaata tacagaattg
     3061 tatttcccta gtcataatgt ccgctacata gcgattgatg acggtgtaga cagcgaaaaa
     3121 ggcgaaagtg agattgcacc atttaagaac atcatcaatg aatgggtggc aagagataca
     3181 agccgtaaag tcaaatcagc atttaagaca aagtttgcgg agggggctca ttacggtgct
     3241 tatgctccgt taggatataa gaaacaccct gacatcaaag gaaaactgtt ggttgatgat
     3301 gaaacaaaat ggattattga aaaaatcttt tccctagcct atcaaggtta cggaagtgca
     3361 aaaatcacaa agcagttaag agcagaaaaa gttccgacag cgtcatggct aaattttaca
     3421 agatacggta cttttgcaca tatctttgag ggaaaacccg aaagtaagcg ttatgagtgg
     3481 acgattgctc atgtcaaggc gatattgaaa agtgaggttt atatcggaaa cagtgttcac
     3541 aatatgcagt ctacggtatc gttcaagagc aaaaagaaag tgcgtaagcc cgaaagtgaa
     3601 tggtttcgag tagaaaacac tcacgagccg attattgaca aggaagtgtt ctatcgtgtg
     3661 caggagcaga taaaatcaag acgcagacag acaaaggaaa aggcaacgcc gatttttgca
     3721 gggcttgtca agtgtgcgga ttgtggttgg tctatgagat ttggaacgaa taagacaaat
     3781 aaaacgcctt acagttatta tgcttgcagt tactacgggc agtttggcaa aggtaattgt
     3841 tctatgcact acattcgtta tgatgtgctg tatcaagccg tattggaacg cttgcagtat
     3901 tgggctaagg cagtacagca ggacgaagaa aaggtattga acaagataca gaaagctggc
     3961 aatgcagaga gaatacggga aaagaagaaa aaggcaagta cattgaagaa agccgagaac
     4021 agacaaaatg agattgaccg tttatttgcg aaaatgtatg aagatagagc ctgtgagaag
     4081 ataacagagc gaaattttgt gatgttgtcc agcaagtacc aaaaagaaca gatagaactg
     4141 gaacagcaga taacaagcct aagagaagaa ctaagtaaaa tggaacagga tatgataggt
     4201 gctgaaaagt ggattgagtt aatcaaggaa tattccgtac caaaggaact gacagcacca
     4261 ttattaaatg ccatgataga aaaaatcctc atacatgaag caacaacgaa tgaggataac
     4321 gaaagaatac aggaaattga gatatattac cgatttattg gaagagttga gtaatcaaca
     4381 agagtaatat ttttaactaa gggaaaccgg cggtgtctat acttgggtca gtcgcacatt
     4441 gggaaaacga ttcggttttg ccgcaatctt tttccaatgg tttgagataa cagttggcta
     4501 cttgaccatg ctgtatttct taactggtgc attatcctat gcaacgggta ttggtgctat
     4561 acaaaacaat aaatatctga aattggcaat cctattgatt attttctggg ctattttact
     4621 ctcacagtta aaaggaacca aatacacttc attgattgct cggatcggtt ttgtagctgg
     4681 tatcttgttg ccagcattag tcttgtttgg cttagggatc cattatgtcg cttcaggcgc
     4741 tccactacaa acgatactgt ctatgaaaac attgattcct gatttttcga aattgcctac
     4801 gctggttgtt tttgtttcct ttattttagc atatatgggc gtagaaacat ctgccagtca
     4861 tgcaaatgaa atggaaaacc ctaaaaagga ttatccatta gcaatgtttg tattggttat
     4921 tctggcaatc attttagata cttttggcgg attgaccgtc gctactacag tacctcaaca
     4981 tggtttgtct cttaatacag gggtgattca atcgttagaa ttcctattaa gacacattga
     5041 tccaaatctt gcatggattg cgaaaattct tgcgattctt gtttgtttag gtgtcatcgg
     5101 agaaattgct tcttgggtaa cctctccttc aaaagcactt cacgtagcag cagaagaagg
     5161 attacttcct gaatattttg caaaagaaaa cacacacggt gttcctgctc atttgatgat
     5221 cgcaaatggg atcgttgcaa caatctgggc agccgtcttt acattaagcg gcggggggaa
     5281 taatctttca tttcttgcag cgatgtcatt gactgttgta atctacctga tgttgtactt
     5341 tatgtttttc gcgggctatt tgaagctggt ttttaaagat gacagtcttg aaagagccta
     5401 tcaggttcca ggcggaaaag ttgtaaaagt aatcgttgct tgtttaggtc ttttgacttc
     5461 actttttgct ttttgtatct catttgttcc acctgctagt atcgcagctg gacagcatgg
     5521 gatttatgaa acgattctga ttgtttctta tcttatcgtc ttagttattc catttacgat
     5581 ctacgcatgc cgtcataaat tccagcatgc agaaaaataa aaaatgaaag ctggttattc
     5641 aaatggaagt aaaagaatta gaacaattga ttggaaaaaa tttccactat tatcaaacag
     5701 gacaagtggc ggattacatt ccagcattag ctgaagtgga tcccaaacaa ttaggtatgg
     5761 cgatttatga tttggataca aaacaactga ttgagggagg agacgccgat gtgcgctttg
     5821 ccatcgaaag catgtcaaaa gttcccgtat tgttattagc aatcaaagac aacggaatag
     5881 aaaaagtctt tcaaacaatc aacacggaac caaccggttt tgccttcaat tctatcatga
     5941 atatggaaat caatcatcgc aaacatccaa tgaatccttt tgttaatgca ggagcgattg
     6001 caacaacctc gttgattgcc ggtaaagatg cagatgaaaa atttgagcga atcttgtcat
     6061 ttatgaaaga gatctgtgat gatcctaata tcacattgaa tgaagaaatc tatcattctg
     6121 aatcaagaac aggtgatatc aatcgctctc ttgcttacta tatgaaaggt aatcaaatga
     6181 tcgaaggaga cgtaccggag atactcgatg cttatttcag acaatgctcc ctcaatgtca
     6241 ccgctacagg catagcaaaa ttagctgctg tgctggcaaa taaaggaatt gctccttgga
     6301 atggcaaaca aatcattact gaagaaagtg ctacaatcgt caaatcaatt atgacaactg
     6361 ctggtttgta tgatgaatca ggagagtttt ccgtccatgt tggtgtacct gcaaaaagcg
     6421 gtgtaggcgg cgggttgatg gcagctgtgc caaatcgtta cggcataggt gtcttcagcc
     6481 cggcactaga tccatttggt aacagcgcag ctggtatcca attgttgaaa gatgtagtca
     6541 aagaactaga cgctgacatc tttgaataac cattcttgaa agaggctggg gtaaaagtcc
     6601 aaacggctca aagctaccta caatgaggct gaaattgtga gcttgtttga cttttgtccc
     6661 agtttctttt tttattggtt tttgaaaggg cttttctaaa taaaaaggaa acaaaaatac
     6721 gatttacaga tatgattaaa taaaatcata agaaaaactg gaggcgtgta tcaggaatgc
     6781 tggaaaatta catcgagcga aatatattta gaaaagtgta tctgtgtgaa caattatttg
     6841 aattccaaga aatagacatc gaacaaacag ctatttctct aagggtgact acaccaacga
     6901 tccttcacga tctagaaagt ctagccgagt gtctagaata ttgtataaaa gaacaagtaa
     6961 gagagaagca taagtataaa ctcgtattca aacatggtat tgctctttct gagctcacac
     7021 agtttctgta cggtcaatct tattttttaa agtttttaag ttattatttt aatggtatat
     7081 tcacgagtac agaactggct gatcttgaat ttatttcttt gagtaaagta tatacaatca
     7141 aaaaaatcgt attggatttt tttaaagaaa atgattattt gaaaaataaa gaaatcatta
     7201 tcccagaatt tgactcgcgg aacatcttgc tagctttagt acgttatgtc aattgggaag
     7261 gctatgaaaa taaaaatccg tatgtagaag aagcttgtaa cgagttgatt gattatgtag
     7321 agactcattt ttttaaaaga agatattcgg aagatgaaaa gtcctttatc atacgagaaa
     7381 tagagatcgc aatcggaaga aaggcatttc cccttggact gaaagaagaa gataagaaaa
     7441 gcgcagaaac gaagccgtta tttcaattag tctgtcaagg attggaagag caaaaaggaa
     7501 ttctagactt acaagaagaa gatgtctatt atattttttc tttgttcaac agtagaaatt
     7561 ataccaatga gaacatggag ctgttaagaa aagatttcga agttgtttat aaaaattttg
     7621 ttctcaatga cctatcactg aatgaattga ttttacagat tattagtatc gctgaaatcg
     7681 acgatgcaga aaattttatt ttcaagcaat cctttttaca atttgtccgt acgttgtggg
     7741 cagatggaca agtattttta ccggaaagga tctatcttct atcagaaaaa gaacaacttc
     7801 tgtacggaaa aattgtagaa atattggaag agtggaaaaa gaaaaatcaa atccaactaa
     7861 gatggaatga aaatttcatt cgaaaattcg tcaaaagtct ttctttgatc aacagtgaac
     7921 aagcggggag acaggaaata gaaatttttg ttgtttcaga aagttcagtc aaacaatttt
     7981 tttatcgaac ccaatttcat ttgtatgcgg aagaaggcat cgctgaaata aatcctattt
     8041 tatttcgttc attagaagaa ttgcctgatg aatgtctatg tgcgaaaaaa agagtggttt
     8101 tgtgcgatgc tgctagctat caaaatggat tagaaactga aaagacaaag atctatccaa
     8161 tctcattaaa aggtgcaaac atccatttgt atcatattgc tcaggaactt cacctattaa
     8221 aaaaacatat ttcttgatga gaccttaatt aggagacctt ctacaaagct ttttaattgt
     8281 ctgtagaagg tttttatttg agtcctgatt cgtgcgaaga tctacttata taacaagctt
     8341 tctctgaaat ttttttaaaa tgctattgac ttagagtcaa ctctaagtag tagaatagat
     8401 aaagtgtaac aaatctattt tcattaaaag aagatagtac ggaggagaga atgtattatg
     8461 agtacagtat tacatgtatt ggatgcaatc aatagccccg cagatgtcaa aaaattatct
     8521 gttgaggaaa tgaaacagtt ggcagaagag atgcgccaaa aaatcttgca aaaggacagc
     8581 gatgtaggtg ggcacgttgg tccgaatcta ggtgtagtag aattaacgat tgcgtttcat
     8641 tatgtatttg attcaccaaa ggataaaatc gtttgggatg tttcccatca gtcttatggt
     8701 cataagcttt taactggtcg aaaaaatggt tttgaaaaag gacattaccg tgaagtgagc
     8761 ggatattcca accaacatga aagtaaacat gactatttta cagtggggca cacatctaca
     8821 tctatcagct tagcaacagg tttagctaaa gcgagagatc tgaagaaaga atcaggaaat
     8881 gtggtagcat ttatcggtga cggctcccta agtggtggct tagcttttga aggattgaac
     8941 aatggtggtg ttttacaatc caatctaatc gtattagtaa acgataatga gatgtctatt
     9001 gatgagaatc atggcagttt atataaaaac ttagctgagc ttcgtcaaac caacggtaaa
     9061 agcagcaata acctatttaa agcaatggga tttgattatc gttacgtgga taatggaaac
     9121 gatctggaaa cggtgatccg tttatttgaa gaagtaaaag atattgatca tccgattgta
     9181 cttcacgtcc atacggaaaa aggtcgcggt tatcagccgg caatcgataa taaaatgaaa
     9241 tatcattggc atgtaccatt tgatctgtcc accggggagg caaagcaagt aacttctgga
     9301 gaaacattta atatgatcat catggattat ttggataaga aaatgcaaac aagtacagct
     9361 cctattgccg cagtcaatgc agcgatacca ggcgcctttg gactgaaaac attccaagaa
     9421 aaacatccag atcattattt tgacgtgggg atcgctgaac agcactctat cactttcgct
     9481 tctgctttgg cttctcaggg agtacgtcca gtcgtcttcc aatcaagtac tttcttgcaa
     9541 cgggcatatg atcaattatc acatgattta gcgatcaacg agaatccagt gattatttta
     9601 gtcggtggcg gaacgatctc agctagtgac cgaacacacc aaggaacatt tgacattcct
     9661 tacttatcaa gtatcccgaa catcaaatat cttgctccag caacaaaaga ggatatgatc
     9721 tctatgctag attgggcgtt cgaacaaaca gcgcagcctg tagcaatccg aattcctaca
     9781 catggtgtag aacatggtac agctatcgca aatgattata gtattccagc ctatcaaaca
     9841 gtaaataatg gaggaaaagt agcaatttta gctttaggcg gttttcttga attaggaaaa
     9901 gaaacagtaa aagcttttag aaaaaaagga atcgaagcaa cgttgatcaa tccaggaacg
     9961 atcacagaaa atgacgtaga aacattagat aaattaaaag aaacacacga attagtcatc
    10021 acattagaag atggtagttt gtcaggagga tttggcgaaa atatcagtcg ttattatggt
    10081 gattcttcaa tgaacgtatt aaattttggt gcagagaaag aattcacgga tagcgttcct
    10141 gtagggcagc tttatgaacg ttatcattta acaccaaaac aaatcgttga agatagtctg
    10201 cgtgtcttga atattcaata attcattatg ctcaccatcc agataattgt ttatactagt
    10261 atctggatgg ttttttcatt ataaaaagca aaggggtgga tgttatgtat cagcaagtag
    10321 aagaatatgt caaaaagttc caagaaaaat atcctagtta tcaatcagaa aaattaggtt
    10381 tcttttcatt tggggataca gaaaaaatgg cagacgagtt gagcgaacta gttgtaaaaa
    10441 agataaagac tggtacatca agtggttacg atctgtataa acaagagaat gagcctttac
    10501 caaaagttgg tcaattagac gtggtcctga atggaaaaaa tgaaccagtt tgtatcatca
    10561 aaaatataaa tgtgaccatc ttgcctttta gtgaagtcac gaaagagcat gcttggaaag
    10621 aaggagaagg ggatcggaca ttagcttatt ggcggaaagt ccatgctgag ttttttaaac
    10681 atgcttataa agaagcgttg aacatagaat ttacagaaga gaagctggtc gtatacgaag
    10741 aatttgaagt aattttcttt tagtaagaaa ggtctgctga aagaaatagc tcattattgt
    10801 ctcctgaata gaaaagggtt acatttttat atgaagctgt atttttatat aacattactg
    10861 gaggagatat tgtggataca ctggaacaaa tcaaaggcgg agtcgtcgtt tcttgtcaag
    10921 ctttggaaaa cgagccgcta cacagttctt ttattatggg gagaatggct ttggctgcaa
    10981 aagaaggcgg agcagttggt attcgagcaa atacgacaga agatatcaat gaaatcaagc
    11041 gaatcgttga tttaccggta atagggatta tcaaaagaga ttacgatggg tcagaagtgt
    11101 ttattactgc gacagaaaaa gaagtggaag aacttttgga gacgcaagca gaaatcattg
    11161 cactggatgc aacttctcgt aaacgtccga cagaaaaaac aactgctgaa cttgtccaaa
    11221 tgattcacga acacggtcgg ttagctatgg cagatatttc gacttttgag gaagcgcttc
    11281 aagcgcaaga agatggtttt gatcttttgt ctacgacttt agcaggctat acagaatatt
    11341 cacgaaagac gcagacacct gattttgatt tattgaatca aatcatagaa caagtcgata
    11401 tcccagtaat tatggaagga catactgact ctcctgaaca agtagagaaa gcatatgaat
    11461 taggtgcttt ttcagtcgta gttggatcta ttatcacccg tccgcaattg atcactaaaa
    11521 gatatgtcga agccgcaagt aaagcaaata actaaaaaac acgcacggca cagattcttg
    11581 acaaaaaaga aaaattgata gatagtttaa agcagattct aagaagatga aaaaagcatt
    11641 acttttcatt ttgtcttcaa gatctgcttt ttaacgaatt ttatagaaag aaggcgaaac
    11701 catgtttgaa cggagtcctt cagaattgac agaacgtgaa aattacaagt tgctgattgg
    11761 ttcagtcatc cctagaccag tagcagtagt aacgactaaa tcagcaaaag atatagtgaa
    11821 tatcgcaccc ttcagttact tcaatatcgt cagttcgaat cgacccatct tatccttggc
    11881 gatccagaga aaacaagatg cagtaaaaga cacagcaaag aatattcttg agacaagaga
    11941 agctgttatc catatccttg atgaggacaa cgtagaagaa gtaaataaaa cagcagccaa
    12001 tctgcctaat gaggaaagcg aactgtacct gactgacttg actttaactg attcagtaat
    12061 catttcagta ccagcattga cagaagcaaa agttcgtttt gaaacatcct tatatgaaca
    12121 tgtcgagata cggaataaaa ataaagtaac agctgattta tttttgctag aagtacagaa
    12181 atatcattta aatgaaacag tctatgatga taagacagga aggatcgatc caagaaaatt
    12241 gaatgctgta agccgtttgg caggaaatga ttatgcagca ataggagaaa ttttcacgat
    12301 tgcacgtccc gaataaaaag gagcactagt tatgttaaaa ataagctata aaccatcgac
    12361 agattcaaaa gaaatgaaaa aagaatatga aacagtgaat gattttctgc aagggcagta
    12421 cttagaagtt ccgccattgc aagaccattt tgtcgttact actgttactt tagatggtaa
    12481 ggaaatagaa atgccagatc aaacgattag cggattgttt aattacttta acaaataaat
    12541 atttattccg aaaagtgaaa aaacatataa aaaaacacat aaaactaaaa aattatcaaa
    12601 gaatcctggt gcaactgaaa gaatttgcaa cgggattctt tcaacttatt tgttattttt
    12661 ttctaaaaaa tattaaagat tgttaaattt cactatttca tttcaaattc cattgcctaa
    12721 tcattaggaa aagtctatca tgaactcgta aatagaatat agtaataacc ttgttaggtg
    12781 aggctcctat acaaacatag gctgttgccc agaaacgtcg aaagtcgcca atgggtaaaa
    12841 cagaaactgt tggattaagg ctttttccaa tagctaagaa tgttttcttt acgttgtata
    12901 gtgctaaaac tcggacgatg agatgatgct aggtcagaat tcttgttcga aaaggtttct
    12961 gaccttttct ttatattttt gtgactgact tatttgatga gacaaactcg ctcctcacct
    13021 gacaagtgga ttgctgtgtg aggaggagat gcggtgaaaa aagatcgatt ggtggatttt
    13081 gggtccttat ttgactttgt ccatgatcgg tcttttagaa gtatacagtg ccagttctta
    13141 tcgtttattg caagccgatg aaaatacaaa aagtctatta ttgcgtcaac taattttcat
    13201 atttttgagt tggagcgtga tcttcttagc tcgttcagtc aaactacact atttacttca
    13261 ccctaaaata gcaggatacg gtttagcctt atcgattttc tttttagtat tagtaagaat
    13321 agggatattc ggtgtcactg tcaacggcgc acaacgttgg atctctctgt ttggcattca
    13381 attccagcct tctgaactgg caaatctttt tttgattttt tatttaagct ggttttttcg
    13441 tgacggaaat agtagcccaa aagatctaaa aaaaccattc ctgattacag taggtataac
    13501 ttttctgatt ttatttcagc caaagattgc tggagcattg atgatccttt cgattgcgtg
    13561 ggtcatattt tgggcagcgg cggttccatt taaaaaaggg atctatctaa tcgttacttt
    13621 ttctgcattg ctgattggag cagcaggcgg ggtattatat ttaggaaata aaggttggct
    13681 tccacagatg tttaatcatg cttatgaaag gatcgcgact ttaagagatt cttttatcga
    13741 tagtcatggt gcgggctatc aaatgaccca ttcgttttat gcactatata atggtggcat
    13801 atttgggcgg ggattaggaa atagtatcac aaaaaaaggg tatcttccag agacagaaac
    13861 agattttatt ttttcgatta ttacagaaga gcttgggcta atcggtgcat tgtgtgtgct
    13921 tttcttattg ttctcattat gcatgagaat cttttgttta agcagtcgct gtaaaaatca
    13981 gcaagctgga ttgtttcttt taggattcgg aactttgcta ttcgttcaga cgataatgaa
    14041 cgtgggaagt atcgcggggc tgatgccaat gactggtgtg ccattgccat ttgttagcta
    14101 cggaggaaca agttatctga tcctttcttt aggaatcgga atcacgttga atatttcttc
    14161 aaagatacag gccgaagagt tggcgctcta tcgacctgaa aaacaataaa gagaaactga
    14221 gaaactctca gtttgaatta tcataaagta caatctttta tttttcaagc gagaggttct
    14281 tttagaaaga ggaattcgca atgaaagtat ctcaaaaaat catattatct attttgttac
    14341 tgcttacatt agtagttggc tatttttcga ttgagtttat ccatggattt tcgtctgcaa
    14401 aacagagttc aactgtgaaa aaggtagagc cgaaaagtat ccctaccaca ctaaatgtgg
    14461 ctttgattgg ttcagatgct cgttcgaaag acgaaaacgg tcgctcggat tcacttctgg
    14521 ttgcacaata caaccagaaa acacaacaag caaaactgat ctctatcatg agagattcat
    14581 atgtcgatat tccaggttac ggaatgaata agataaatgc agcttactct tatgggggag
    14641 ttgatttatt aaatcaaaca ttaaaggaaa atttcaaatt tgaagctccc tattatgcaa
    14701 gtatcacatt tcaagatttt atcgattgcg ttaatgaact gtttcctggt ggagtcaaga
    14761 tcgatgcaga aaaatctcta gatttagatg gcgtatatat aaacaaagga gagcaagtga
    14821 tggatggtaa tactttactc cagtatgctc gatttcggga agacaaagaa ggagacttcg
    14881 ggaggatcag aaggcagcag caagtgatca aagctatctc tcagcagctg aaagacgtaa
    14941 cttcaatatt caagctaccc aaagcggttg ggaaattact tggtagtatc caaacgaacc
    15001 ttccagaaag tgtgcttctg gattgtggta tggatttcct caaagacata tgttagaata
    15061 aacaggtata aatagtgaaa taaaggaatg acaagcaaga gaaggaggaa aaaatgaaaa
    15121 gaagtgacaa gcacggcaaa aatcgaacag gcgcttatat tgccggcgca gtgatcttaa
    15181 tagcagctgc gggtggcggt tatttttact accagcacta tcaagaaacc caagcagtag
    15241 aagctggaga aaagacagtt gagcaatttg tccaagcttt gaacaaggga gattataaca
    15301 aagctgcaga aatgacatca aaaaaggcgg caaataaaag tgcattatct gaaaaagaga
    15361 tcttagataa ataccagaat atatacggtg ctgctgatgt caaaggactt cagatatcga
    15421 atctaaaagt agataaaaaa gacgattcta cttacagttt ttcatataaa gcaaagatga
    15481 atacctcatt aggtgaattg aaagatcttt cttataaagg aacattagac agaaatgatg
    15541 gtcaaaccac gatcaactgg caacccaact tggtttttcc agaaatggaa ggaaatgaca
    15601 aagtaagcct gaccacacaa gaagcagcaa gagggaatat tatagatcga aatggtgaac
    15661 cattagcaac aacaggcaaa ctaaaacaat taggagtcgt tccaagtaaa cttggagatg
    15721 gaggcgaaaa aacagccaat atcaaagcga ttgcttcctc cttcgactta acagaagatg
    15781 ctatcaatca ggcgatttca caaagctggg tacaacccga ttactttgtc ccattgaaaa
    15841 tcattgatgg agcaacgcca gaacttccag ctggagctac cattcaagaa gtagacggca
    15901 gatattatcc tttgggtgaa gcagctgctc agctgattgg ttacgtggga gatatcacag
    15961 cagaagatat tgataagaat ccagaattaa gcagtaatgg aaaaatcggt cgctcaggtt
    16021 tggagatggc ttttgataag gatcttcgtg ggacaacagg tgggaaatta agcattacag
    16081 atgcagacgg tgtagagaaa aaagttctga tcgaacatga agttcaaaat ggcaaagata
    16141 tcaaattgac aatcgatgcg aaggcacaaa aaacagcttt tgacagtcta ggaggaaaag
    16201 ctggatcaac tgttgcgaca acgccaaaaa ccggtgatct tcttgcgctt gctagctctc
    16261 caagctatga tccaaacaaa atgacaaacg ggatctcaca agaagattac aaagcttatg
    16321 aagaaaatcc tgaacatcca ttcatcagcc gatttgcgac aggttatgct cctggatcta
    16381 cgtttaaaat gattacagca gcaatcggtc tcgacaacgg cactatcgat ccaaatgaag
    16441 tgttgacgat caacgggctt aaatggcaaa aagacagttc ttggggatct tatcaagtaa
    16501 cgcgtgtcag tagtgatgta tcacaagtag acttaaaaac tgctttgatc tattccgata
    16561 atatatatgc ggcacaagaa acgttgaaaa tgggtgagaa aaaaattcgt acaggcttag
    16621 ataaattcat ttttggtgaa gaccttgatt tgccaattag tatgaatcca gcacaaattt
    16681 ctaatgaaga tagctttaac tcagatatct tgctagctga tactggatat ggacagggcg
    16741 aacttctaat tactcctatc cagcaagcag caatgtattc tgtttttacc aacaatggca
    16801 cacttgtcta tcctaaattg attgcagata aagagacaaa agataagaag aatgtcatca
    16861 gcgaaacagc agtacaaacg atcgtgccag atctgagaga agttgtgcaa gatgtaaatg
    16921 gtacagcaca ttctctttct gctttaggga ttccgttggc agcgaaaact ggtacagcgg
    16981 aaatcaaaga aaaacaggat gtaaaggggc aagagaacag tttcttgttt gctttcaatc
    17041 ttgataacca aggttatatg atggtcagca tgttggaaaa taaagaagat gatgattcag
    17101 caaccaaacg agcatcggaa ctattgcaat acctcaacca aaattatcaa taaaaaattg
    17161 ctttttaagt acagtaaaag gactgtggcg ttatcgtcac agtccttttt tcaaataaac
    17221 ggttttcacg atgtctcttt cacaacttct ttttgattta ctcacacttc ataaactttt
    17281 tttgtaaaat atttgagaac aagtggagaa ataagtgtac ttaataaaat cacgataact
    17341 aaaggtgaat agtactgtgg ttcgatcaat tgactttgct gtccaatttg taaaatgatc
    17401 aaagccattt ctccacgcga aatcatacca gcaccgacca tcaatgaact atgttgagaa
    17461 aaaccggcaa tctgagcacc aaaataacct ccaagcaatt tggtcaaaat cgctacaagc
    17521 gtcaatatag aaataaagag tagttgttca ctaaagtcag aaaaatcaac ttctaatcct
    17581 acactgacaa aaaatactgg tataaatact gcatatccta aagcctctac attgtggtat
    17641 acttcttctt taacctttgt ctgactgaca gctatcccag caaaaaaagc accaatgaca
    17701 gagctaagcc caacaagatc cgctacgtaa gacattccta aacaaataac tagcgatacg
    17761 atgataatag aagaatttgc gtacactttt tctgcaaatg aaagtaggaa aggcgcaatc
    17821 catttgacta ataagaaaat aaaaacaaaa taaattagct gttcaatcaa aacaagcggt
    17881 aaagaagcat tgctagaagc ttcccccgtt agaaaagata ggctgaaact tagaactaaa
    17941 acgactaaaa tgtcatctac cacagaagca cccaaaattg ttgatccttc ttttgtattc
    18001 actacgttta gttcttttaa tacttctact gaaatactga cagaagttgc cgcaagaata
    18061 atcccaaaga aaatcgcttc atttcccgaa acttggaatg ctttgcctgt caaccagcca
    18121 aaaacaaccg ggaagatgat cccaagcaaa gcaacgaaca taccaggtcg gaaatatttt
    18181 ttcaaaagag ataaatcact ttccagacca gctaaaaaca ttaataagat cacaccaatc
    18241 tccgaaaagt catggactag aatatcaggt ttgacccaat tcaatccagc ttggcctagc
    18301 aaaacaccaa caagtaattg tccaatcact gctgggatac ctaatctccg cgagatatgt
    18361 gagccaatcg ttgttgaaat caatatcagg cataaaatac caataaattc cattctcatc
    18421 attcctttgt ataaaatata gcccgaactt agcataacat acattattga aaaaatagga
    18481 aaatatactc acaaaaaaac caacaatcca aaagattttt ttggattgtt ggtttttata
    18541 cggtctattt taataactaa aaatgattaa cgtatagtca tttttcttat tctgatgaaa
    18601 ttgataatct cctggatgcc catgaaaatc aaaataaagc cgaatatttg gaatagaagc
    18661 atcaaacttt tgaatggatt gaacaataag acgaatccgc caatcaacaa cagaatacta
    18721 ctataaacac tccaactttt agcttttgta ttcatgctga agaacaactg gaacaagctg
    18781 ttgatgataa cagctaatcc aagaagaatc ggcaggatag aaacgattgc aggtgcaaaa
    18841 gcatagacga tcagagctaa gatcaggaaa aaaagaccac tgaacagacc gatactccaa
    18901 gaacctgttt tccttttaaa acggtaagcc tcaaaaagat tcaacaaccc aagcaaaaca
    18961 agataggcgg tgatcagata accgataaaa tgaaaaacag cagaagggtt tagcacaatc
    19021 gcaatcccag aaataatata aacagcagct cttaataagg cgtatttttg aatattttgt
    19081 ttaatcgtct caaacatata agaaaacctc ctttgactta ttttaacgtg aactagtcat
    19141 tttaccaaat taaatgttac aaaatgagcg aaggagaaga atatctctgg aaaaatcaac
    19201 ttctgaggat cttttccatt tttttgcctt ttgctagctc atcgatcatt ttatctaaat
    19261 aacgaatttc tttcatcaag ttatcctcga tgtcttctac tcgtacacca caaacaacac
    19321 ctgtaatcaa ggaacgtgaa ggattgggga caggggcttc cgcaaaaaat tgttcgaaag
    19381 tcacttgttt ttgtagttga tattctagtt ctgtttggga ataacccgtc agccaacaaa
    19441 tgatttcatc tacttcctct tttatacgat cttttctctc cgcttttgct acatacatag
    19501 gataaacgct tgcaaaactt gtcgtaaaaa tacgattttg cgccataatc agtcaccttt
    19561 ctttttttca aattatttac tacttatagt atataagaaa aagagaagaa aaagcgatta
    19621 ttcaaaaaaa caaaaaggat tgtgacaaaa ttcttgtcac catccttttt tccgctctct
    19681 gactttttac aatcttcata gctcaagtgc gcatcagata atcgaatgct cctaaagctg
    19741 cagtagctcc tgaacccatt gaaacaatga tttgtttgta tggactatct gtacaatcac
    19801 cagctgcgaa aacgccgggg atattcgttg cgccattttt ctcggtcact atttcatttc
    19861 ttggattcat ttcgatcgtt ccatctagcc aatccgtatt agggagtaag ccgactagaa
    19921 tgaatactcc tgaaacagct agtgtatgca tctccatcgt acggcgatcg atataggaga
    19981 gagattctac ctgattcgta ccgctgattt ctttcgtcgc tgcatgtttg ataacagtga
    20041 cattcgcaag agagactagt ttatcctgta agatttgatc tgcttttaat tctggtaaga
    20101 attctagaac atatacatgt tttgctaacc cagccaaatc gattgctgct tcaacaccag
    20161 aattaccacc accgataaca gcaatctctt ttcctttaaa taaagggccg tcacagtgtg
    20221 ggcaataagc aattccttta tttttaaact ctttttcgcc tggtacattg atagaacgcc
    20281 agtgcgcacc tgtcgcgatg atggcggttt ttgctttaag tgatataccg ttagctaagc
    20341 caatattaat aaaatgttgc tctttattta aggaaacggc ctgttgattc atcataatgt
    20401 cgatagggta actacgcaca tgactttcta cttgctgcat caattttgga ccttctgtgt
    20461 aagaggtacc aatcatattt tcaatcccta gtgtttcaac gacttgtccg ccgaaagaat
    20521 cagcgacaag tcctgtacgg attcctttac gtgctgcata gatagctgca ctactagctg
    20581 ctggtccacc gccaatcact aatacatcat aaggttcttt ttcaaacaac tcttcttcaa
    20641 tcaaagggcc agtgattttt tcaacaattt gttcgatcgt catgcgtccg ctactaaatt
    20701 cttctccatt taaaaacaca gttggcactg ccatgatttt tttatcatcg atttcttttt
    20761 ggaacatccc accttcaatc atcgtatgag taatatttgg atttaataca gctaatatat
    20821 tcaatgcctg tacaacgtcg gggcaattat gacaagtcaa gctaacataa ctgtcaaaat
    20881 gcaatgtttg tgttattttt ttgattttaa gactcaaaga ttcactgatt ttcggtgccc
    20941 gtccactaat ttgtaacata gccagtaaaa aagaggaaaa ttcatgaccg agggggatac
    21001 cagcaaaaac gattccactt tctttgccaa ctggattgat agaaaaacta ggtgtgcgca
    21061 tcgaatctct tttttcccaa gagattttag gagacatttc tgctatttcc ttcgtaaatt
    21121 cagctagttt ttgactattt tcactattat ccaaactaac agaaaaaaca ataggagatt
    21181 caatcagtgc taaatattgt tcgagatttt gtttagtttc tttgtctaac atatccacca
    21241 cctaaatctt tccaacaaga tcaaaacttg gtttcaatgt ttcgccactt tctttccatt
    21301 ttgccggaca aacttcacct gggtgggtac gtacatattg agcagcgcga atcttatcaa
    21361 tcagtgcact agcgtcacga ccgattccat ctgcattgat ttccatagct tgaacgattc
    21421 cgtctggatc aataataaat gttcctcgct gagctaatcc ttgctcttca tccaaaacat
    21481 caaaaatacg agaaatctga tgagacggat caccgatcat cacgtattcg attttaccga
    21541 tagcatctga tgtatcatgc catgctttgt gagtaaagtg ggtatcggta gagcaagaaa
    21601 agacttcaac acctaaagat ttcaatgtac tgtattgttc ttgtaagtct tctaattcag
    21661 taggacaaac aaaagtaaaa tcagctggat agaagcaaag aatactccag ttccccataa
    21721 gatctttttc actgacttct aaaaattctc cttgatgata agcatgtgca ttaaattctt
    21781 cgattttttt cccaatcaat gacatagtaa aacctccaat aataattatt tatttataat
    21841 tattgtaatt tagttggagt tgcaaagtca atggatattt tgttatttaa taaagattac
    21901 tcaaaaacga aggttaatta taaaaataga agaggtcgca agaaaatgct actgctggaa
    21961 atactcggga taacgttgag taacagtttc ctgttctttc agcatcatgt gtaagtgcaa
    22021 tcccgtttga aatcgagctt cttctggttt tttatcaact aaagccttga gtaaatcata
    22081 atgttgttcc atgatcgttt cccatggaag cccctgaatg gtcactcgta accagcggaa
    22141 acgttctaaa tgggtattat ggtcatctaa ccagttccaa acttcttttc ttcctgcaat
    22201 ttcgaaacaa gcttcatgaa ataaattatc tgcacggaaa aaagcgcgtt cgtcatttat
    22261 tttgactgct ttttcttgtt cttctaaaat cgtttctagc actattcgtg tttgtgtgtc
    22321 caatttggaa caacattcaa tcatgatttg ctcttccaac tgttctcgga caaagcgagc
    22381 attttctgca gaaacaagat taattttgga aacatacgta ccactttgag gtatcgtata
    22441 cacgagttct tgctgacgta gttgaatcaa tgcttcgcga atgggagtcc ggccgatagc
    22501 aagatgttcc tccagtgcct tttcagatat tttccttcca ggttctaagt cagcatagat
    22561 aatttgttta cgaatcgctt gataagcttg tgattgcaag ctgcttttca tctttattcc
    22621 tccaaaatca tttctatgaa cgtagtataa cagaagaggt ctgaaaaaca atctggtatg
    22681 tcacattaac tagtaaattt gtataaatag taaaattttg gttgacatag cgatttttat
    22741 tgcataaaat tcacttgaat acaaaaacta atatgttagt ttaggagggg aaaaatgatt
    22801 gatttaaaca actggaggaa ctttatccct gaattatctc aaaaagaagt agaaatacct
    22861 cattttgacc gtgcatcatt aagagaaaat ggacaaaaaa atcctgtctg gatccatttc
    22921 ggtggcggaa atctttatcg aggatttcat gcagaaatcg ctcaacgttt agcggatcta
    22981 ggcgaattgt ccactggtgt cattgtttgt gaaacattcg atgaagaaat aattgaaagg
    23041 gcttaccaag attttgatga tttgattctt gaagtggtca tgccaagcag tggagagttc
    23101 gtcaaacgta tattagctgc gacagctgac agtctgtatt gtcatccaga ttgttctgaa
    23161 cactttgata agatgattcg acactttgaa aatcctagtt tacaattagt tacttttgct
    23221 attactgaaa aaggttatcg attgaaagat acaaataata aatatatagg accgattgca
    23281 gtcgatataa aaaatggtcc aaagaagcca tcacatacaa tgagtattct tgctgtgcta
    23341 ctttataaac gttttttatc tggagcttgg ccgattgcac ttgtctctac agataatttt
    23401 tcacaaaacg gtagtcaatt acgtacttct ttgctaacga tcgcaaaaga atggcaaaag
    23461 gaaggttatg tacaaaatac atttatccaa tacttatcga atgaagaaat tgttgcgttt
    23521 ccatggacga tgattgatcg tatcaccccg aatccttcct tgtcagttag caaaatgttg
    23581 gcaaaagagg gcttttcaaa tatgtcgatt ttccaaaccg caaaaggaaa taatattgct
    23641 ccatttgtca atacagagga catccattat ttaatcatgg aagatcattt tcccaatgga
    23701 cgtccgaaat tcgaaaaagc tggggtattc ttgactgatc gtgcaacggt agataaagca
    23761 gatacgatga aggtgacgac ttgccttaat cctttgcata cgtctttagc tattatgggt
    23821 tgtttactgg ggtataggag catagctgag gagatgaaag atccagattt atcgctgcta
    23881 gtttctgaaa tcgggtacaa tgaaggcctc ccagttgtgg agtctccagg tatcattgat
    23941 ccaaagatct ttctggaaga agtaattact gtgcgctttt ctaatccaaa tattcctaat
    24001 atgcctcagc gaatcgccac ggatacctct caaaaggtgg cgattcgtta tggtgagacg
    24061 attaaaaaat atatggaaat agaagttaaa gacccgcaga cacttgtatt cataccattg
    24121 actctcgctg cttggcttcg ataccttatt ggcattgatg atcaaggaaa accattcatc
    24181 ccgagtccag acccactatt gacagacctt cagcataagc tttccgatat tcaactgggt
    24241 acgcaagata catcacatat tcatgagaaa atggctccta ttttgtcaaa taaagaaatt
    24301 tttggtgtag atctttacca agcagagctt ggcagaaaaa tagaagaaat gttcatcaag
    24361 atggtagcag gaccaaatgc cgtacgaaaa acattacagg attacttaca agaacatgga
    24421 ggaaatttat catggaaatg acttttagat ggtacggatc acaggaagaa aagattacct
    24481 tagatgaaat cagacagatt cctgcggtca aagggattgt aggcacattg atggatatac
    24541 cagtaggaga ggtatggcct agggagagga tcaaagaact aaaagaagaa attgagtctc
    24601 gtgggttaac actaaaagta attgaaagcg tcaatgtgca tgatgccatt aaaattggat
    24661 taccttcccg tgagcagtat atcgaaaact ataagcagac aatccgaaac ttggcagaat
    24721 atggaataga agtcatctgc tataatttta tgcctgtatt tgactgggtg aaatctgacc
    24781 ttgactaccg cttagaagac ggctcatcca cgttagcttt tatatctgat gatattccag
    24841 atgatccaag agaaatcgtc gcgcgcatcg aacattccag caatgaattt ggattgccgg
    24901 gatgggaacc tgagcgctta gctcctatca aatccttgct tgaagcctat gcatcagtag
    24961 acgaagaaaa acttcgagaa aattttgcct attttctcca atcaatcatc ccaacatgtg
    25021 aagaggtagg ggtcaaaatg gctgtacatc cagatgatcc gccatactcg atttttggat
    25081 tagctcgaat cgtaaagaat cgagaagatt tagattggtt gtgtcgcata gtagacagcc
    25141 cttataacgg aatcactctt tgtacaggga gtattgcaga agatccagaa aatgatgtat
    25201 atgggatttt agcagaattt tgccaaagag atcgaatccc atttgcacat gttcgaaata
    25261 ttaaattttt agctaatcga gatttctatg aggcaccaca taaatccgaa tacggttcat
    25321 tagacatgta ccgcatacta aaaacaatgt atgacaacgg atttaacgga tacatccgtc
    25381 ctgatcatgg aagaatgatc tggaatgaga caggaagacc aggatacggc ttatatgatc
    25441 gagcattagg tgctgtttat ctaaatggat tatgggaagc aatcgaaaaa ggaaacaaaa
    25501 gtaaagataa ttagtgaaaa aaactgtaat tttattatgt aaataagaag gatgttcaaa
    25561 ttcttgatac ataaatccgg aggttgttaa taagcattcg gatttatgta tcttatttgg
    25621 tctaggaagt aacttgattt tcttttttcg attgatccat gagtgcttct tcttttaatt
    25681 caaagatata ttctgagatc ctcataatca cttttttcca gtcttctggt gtgatgattc
    25741 cttttaaaat atagattttt ttgatatgag aaggcaattg tttcaaaggg cagtcgctga
    25801 taacgatgtt gcagttctcc ataaaatcat tttgtatttt gatcgattca tttgaaaaaa
    25861 tttgttctat cttaacgatc agatctttac tgatataaaa atcacgcgta tagttcacac
    25921 caatcacaat tcgcggctgt tttttgtagc gatcatacaa atgtactagg tcttcaacca
    25981 tccattgcac attttccttt tctaaaataa ctggtaacaa gtgttgattt tgttctctga
    26041 aatccatata aaattgttca atggcggttt ggacttcttt caatacgcta tgttcttgat
    26101 aaagcatgaa agtaggaagg ggcgtatttg gttgattgaa gttaagaaat ccattataaa
    26161 gtttatttcg tgcgaatgcc aatgagtaaa gaatcttttc tttttcaggt ataaacaaat
    26221 caaatacagt acaaagggac tccaccattt ctcttgaata aagaacatga ggaacgtttg
    26281 ctttttttaa aagtttgtat tgctccaagc ttgtttcttc cgattcgatt ttcgtgatag
    26341 aaagtcgagc taaaatattc actaagatgc gttgttcgcg acaaattggc agattaggtc
    26401 gcaaaatatc tacagagaga tcaataaaaa agtcaatata ttcatactct gtgaattctt
    26461 tttgtacgtc tttcacagaa gttgcaggaa aattctcttt acatattttt aatagaaaat
    26521 ataatttatc tatcataccg ctatttagtc ggtcaagtac ttctttttta aaaaaagtat
    26581 tcatcataaa agccactact tgcggatctt catcataaaa ttctgtagca gtacttgaaa
    26641 agatgttcca ataaatatct aatgctgcat attgaatttg tacctctttt ccagaaaaag
    26701 actttctgcc attattagaa aaggagatag acaaaccgta ctatgctaaa aatgcattaa
    26761 tctttttcat tttcgtatac aaataagagg cactatagtt tgtttgctga ctgaaactga
    26821 taatcgaatt tgtctgacag ctgaacaaag aagtcaagat ctgataactg actgattcgt
    26881 tgcagtatct tccaaataga cgataatagc agtaagccgg atcaattcct tcaaaattca
    26941 actttaaaaa aggtttttgc ttatcaatat gcagttctgt tagattgaga cgctcaaagt
    27001 cttgttctaa ttctttgatg tatagtaaaa aatttgattc agacatatgg aaatgatctg
    27061 ctaaatattg tgtagtaata aagaaacgat gttcagatag gaaaagaaaa atatctaatt
    27121 ttgtattgct ttttttcttc aagataaacg ttttaatcgc ttcttgagtt tgcatgaaag
    27181 aggctccttt ttacttaaat tgttaaaact tgaaaatatt actgtttttt tcataaattt
    27241 agacaaaaaa acagtaaaca tataggtaga atctctacta tcttatttct tgcatacaaa
    27301 aaaatcaagg agtgagagag ttatgagata ttcaaccatc ttaatatcaa catttgcagc
    27361 cttaagctta tcgcttacta taaatcagac agtccacaca gaggagacag aaacagccaa
    27421 atggacagaa accaagtggg ccaacgtcaa tcgaattacc tttcaggatg aattttcatc
    27481 cttcaattca ggagtcgcaa aattaagaaa aggacaaaca gcgaccatca aagcaaaaat
    27541 tgactattcg ggagacttag cacctatact acaatcagct gttacatttg agaatgttga
    27601 tcccactttg tcgattggct atgacgagaa cactttgact atccaacaca agcaagcgat
    27661 atttaccttc accgttacat taaatcagga cttgttaaaa ccagcgcttt ttactgtcaa
    27721 ggtatcagat ggactaccga acgatcatca tttaacgccg tatagtcagc ggcagacaat
    27781 tgagcaagat tcagccatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc
    27841 agaaaatgaa aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc
    27901 ggaaatagaa cctggagaag aacccgatac agaaactcaa ccagagccag acaataaatc
    27961 aaaacctgaa ataacccctg gagaaaaacc agatgtaact ccagaaccag atacggattc
    28021 tggaaaccaa acagtaccgg aaacaaatcc agacacagat aatgaaactg aaaatccaga
    28081 aaaaccagag gtagatccag aagaaaaacc agatgtgact ccagaaccag atacggacgc
    28141 aagagaccaa ggaataccag aaaaaataaa caaaaaaaca attcaagagg atggaaaaaa
    28201 agagagtaaa aaatcaaatc tagcaattct aaaaataaat gaagagcagc tgaataaaaa
    28261 atcacgaata tttgatagcg cccaatcagc tgaaacctta aaaagtagca aggatacaac
    28321 ctttgctgtc ctgaaacgaa aaataaacag ctaccaaaat ccggagagtc acaaaacaaa
    28381 gttatactgt ggagcggaat cattctatta agtatagcaa caatgctttc tgcaaaaaga
    28441 tttaaacaaa acagatctct ctaacatttg aataatgtct gtgaacgcat ttttcaaata
    28501 aaaagaaata tccagaaaat gaccccaaaa taccagattg aaatctgata tttggggtcg
    28561 ttcatacttt atctttcttc atatttattt taagggatat ctgtttcttt tggaagatgg
    28621 ttcgggatct ttttcacttt caatacatct aaaaagaagg taaagatcgg aatgccgaca
    28681 atcaagcccc aaacgccaaa gaaccgttcg ctaacaagta agaccacaaa tgtataaaaa
    28741 atcggcagtt ctgttttgct ggacatcaac ttcggattca gcacataaga ctcaattaga
    28801 tggacaatca aaatcgtaat caggatataa acaacatctc ggatgcctcc ttgggaataa
    28861 gctatgaaag atagaggaat acaagaaatg ataacacctg ctactgggat cagacttaaa
    28921 atgaaaatca tgatcgctaa actcagcagc tgatgaaagc caaatacagc caaggcgatt
    28981 gtagtgagca acgtatttaa aagagcgaca acaaattgag cttctaatac caaaccaaat
    29041 gtattgacaa acttatcggc aaaatagtaa atatcttgaa agaaccaaga aaattcactt
    29101 tttaaaaaca atcttgagaa tacaattgtt tttttctttt caatcataaa aaagaaactt
    29161 aagatgaatg acatagcaaa cgccactgcc atttttccta tatcctgtaa atagccaagc
    29221 gcaatcgaag cgccattttg aagctgttca aaaaaatcgt ttcgctcaat ataagtatgg
    29281 atatattgta aaacaggatc tgcatctttt ggctgatgct cgtaaaaatt aataacggac
    29341 tggatcatgt caaatgtttg atgaataagc atcgggatat actttgtgaa tgccagatag
    29401 ataaggtaaa cgatcagtgt ataaatcatg atagctaaaa cacctgtagg gattcggaca
    29461 aatcgctgaa tgatttgaac aagatgaatc atcaaataag taaagataaa tgtgagcaaa
    29521 atggttgtaa tcatacttct aactaagaaa agaacaaaaa cgacaaataa taaaacagtg
    29581 agacggcgta ttttttcatt cgccaaaaaa cgctgataaa cggtcaaatc gacaacctcc
    29641 aaataacaaa aaataaacac gttattcatt atatgatgga atatgaaaat aagaaagagc
    29701 aaaaagaaaa accgctaaat gacgttatct tatgagttgg ttttcctcat aaaatcgttc
    29761 atctagcagt ttcagccctt tttctggtct tgatgaaaat tatctagcat ttttcgggtc
    29821 agatgttgca gtgtatccaa ttcttcctgt tcaagtggaa gataagactt gatcttttgt
    29881 ggaatacctt ctgcttgttt ttgcaacgca gcaccttgag cagtcagcgt aacatttacg
    29941 attctttcat cacccgtttc acgctgacga ttaatataat ttttttctgc taactttttt
    30001 agtaagggag tcagcgtacc agaatccaga cacaaatcat ttcctagctc tttcactgaa
    30061 gtctttttct tttcccataa aactaacatc acaagatact gggtataggt aagattcagc
    30121 ggcttgagga ggggagtgta gtgtctaatg atttctttag aggcggcata taaaggaaaa
    30181 catacttgat taactaaata tagatcttcc atttttccac ctccgctgtt ttactatagt
    30241 gtatcatagc ggatttacac aaaaaagtct attcactaac tgctttcaga gtaacttcta
    30301 tatttccagc tgtagctttt gaatacggac acactttatg cgctgcctct aataattctt
    30361 gcgtttcttc cagagaaaga ccttcgatag atccttcaat ctctacacct aagacaaagc
    30421 tcgtttcact ttctgaataa agggaaactt gtgcactgac agtagaagcc ccagagatat
    30481 ttttttgctg tttgatcaat tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa
    30541 acaattgttc agggttggtt gcattttcga cgcgtttacc aggagctgca atattcaatt
    30601 cgaatgtacg atcgggatta tgcacttctc cagagcgtcc gcctgtgttg atcattttcg
    30661 tagaatacat ttttttcata aaattaccac ctttaattat attttataca attgaatttt
    30721 acacaatata attgtggaaa gcaaagaaat ggattggcat aagataaata agagaaagca
    30781 catgaaacag acgcgctttc tcgaatagca aacatataca aaaaatatca gagacaaaaa
    30841 ataatctcat cataaacatt acatatattt ctcaaaaagt tgttttcttt cttcaaaaat
    30901 tacttcacga tggacctgat gaagcatcca taaataacca aaaggatctc tgaacattga
    30961 gttagtcaca ccaaagtcca tcatttctgt catttcttga atctctacac agccatttcg
    31021 taatgcttta ttatgtgtgt cctcgatatc agagacgatg atattgaacc agatcgtatt
    31081 tggatgttca gcagtaggag cagtcaaacc aagagacgtg ttttcatcca gcatatggaa
    31141 tctcgtacca tacaaggtaa aaatgacttc attattgcct ctagggtaat ctgttgcctc
    31201 aatcagttgt atttcatcaa agattgtttg atacagttct agtgctttca aactatcatt
    31261 taatacaaaa tcgatttccg ttcctttatg cataaagatc tcctctcctt ttcagtcgaa
    31321 cagttactag attcttttat tataccagct aaagaaaacg cattcaaaaa aatagcggat
    31381 ttacttacca actcattcga ttggatgata agtaaatccg cgtcccatta cttctgctac
    31441 gctgctgaca atgacaaagg cacttggatc gatttcttct atcaatggtt tcattcggga
    31501 aaattcatga tcagtcacaa cgatcaataa aacctctttt gactttcgat tatacccgcc
    31561 ttttgcctct agcagggtaa ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc
    31621 ttccaaataa tgttcactca tgaccataac agatttcttt cgattgatac ctgtttcgat
    31681 ataagtcatg acaattgaag tgattgcaat agataaaata gcataaagaa actcttctat
    31741 tccaaaaata aacagattaa gagaaacaac gaatgcgtct gtaaaaaata agccaatcga
    31801 agtattcaag tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga
    31861 agagttgttt ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac
    31921 agacaacaac cgatctgaag taatcattgt ttctggaact attgcaatga ttaaaggaaa
    31981 aaccaagctt ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata gaagagctag
    32041 taccaacata acgatattca acactaaaat aactatagct cggtcaaagc ctaaagcagc
    32101 ttccagtaat attcctagac cgctgacacc tccagcagca atatgatgag gccctaaaaa
    32161 catattgata gcgactccta atatgaagag ggcaaaaata atcttaatgt atgtccatat
    32221 aaattgtctc gtttctttca tttattcact tccttaattc attaataata ctcttatctt
    32281 attataactt acttttcacc ttaagttaac tttaattaat aaaaaaatta ggctagtcta
    32341 aattattatg tttcattctt ctagaatata cttctacgcc aaaaactgtt aaaaaacttt
    32401 tactttagaa aattggagaa attgatcgct taagataaat tcaggacact aaatagtaca
    32461 ggaagtagac taaaactttt aaaagtttta agtctatcta tttggcaagt ttaaaaaata
    32521 aaaattcggt atcaaaaaac tgttaccgat aacatttttg aaagcgttgt cttttgcttc
    32581 tctatcactt atagtgatga cgtcatatta aaacacaagg aggaaatcaa tggatacagc
    32641 tgcaatttat catcgaccgg aaagtgaata tgcatttcta tatacgaata caagatttcg
    32701 tattcggctt cgtactagga aaaatgatat caaaaaagta tatgtgctat gtggagatcc
    32761 atataccata acaactgaaa aatggtatca aaaacaacga ccaatgaaaa aatgtctaag
    32821 taccaatgtt catgattatt gggaaattga agtgacgagc gaaacaagtc gcttacagta
    32881 tgcgttccat gttgttgggg aagataacac ggactgtttt tacggtgatc aaggaatttt
    32941 tccttatcga gaaaatgtga ttactgaacc aaatttttat tttcgaatac cttattttca
    33001 tcaaatcgat cgattcacta ttccagaatg ggtaaaagaa acagtatggt atcaaatttt
    33061 tcccgaaaga tttgcaaacg gggacaaagc aaatgacccc gaacacactt taccttgggg
    33121 aagtaaagat ccagaccgag aagacttttt cgggggagat ttgcaaggtg tgatggatca
    33181 tttggattac ttgacggacc ttggcatcaa tggcatctat ttttgtccca tatttaaagc
    33241 cacatccaat cataaatacg atacgattga ttattatgag gtggatcccg cttttggcga
    33301 taaaaaactt ttaaaaaact tgattgatga agcacataaa agagggatac gtatcatgtt
    33361 cgatgctgta ttcaatcata tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa
    33421 cggagaaaaa tcgatctata aagactggtt ccacatccgt tttttcccag tagattctta
    33481 tcagatgact gacttaccag aaactgctga aaatatccca tatgatactt ttgcttttac
    33541 tccattcatg ccgaaactaa atacagcaaa tccagaagtg caaaaatatt tgctggatat
    33601 cgcaacttat tggataaaag aattcgatat tgatggatgg cgtcttgatg ttgctaatga
    33661 agtcgatcat catttttgga aaaaattcag agaagcagtt acagaaatca aaccagacat
    33721 ctatatcctt ggagagattt ggcattcctc tcaagcttgg ctgcaagggg atgaattcca
    33781 tgcagtgatg aattatgcat ttacagattc gattaaagat tattttgcaa aaaagaaaat
    33841 cacagcttca caaatggtca gtggaatgaa tcatcagcaa atgctttaca gagatcaggt
    33901 gaacgaagga acattcaact tattagattc tcatgatact gccaggatct tgaccctttg
    33961 ccaaggtaac aaagaattga tgaagtctgt gatggccttt atgtttcttc aaaaagggtc
    34021 tccttgtatc tattacggga cagaaatagg gatgactggt gaagatgacc cggattgccg
    34081 caaatgtatg atatgggaga aggaggaaca agatctagag ctattcggtt ttataaaaga
    34141 acttgtttct ctaaggaaac agttgtctaa gattatttct gaaggttcta ctcagtggct
    34201 aatagtaaat gatcgtgaag ataagctcta tttcacacgg aaactagagg gacagatcat
    34261 ctatgtttac tttaatcagt caaaagaacc ttgggtagta gaacaggaaa atgaggtgat
    34321 tcttagtcaa aattgtcagt tgttagaaga cgggaaagca gagatacgac aatacggatt
    34381 tttgatcatg tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc aaatgaagat
    34441 ttgtgcccat tataataagg gtgtaacagc acgttgaata caaaggagga aatgaagatg
    34501 aaaaaaagaa gtgtgaaaca gttgggttta gggttaatct ctttaggaat cttaggcgga
    34561 ttagcggctt gtggcaatgg taactcttca gcagaagggg aagccgatga aggaaaaacg
    34621 ttaacagttt ccgttgattc tggatataaa gattatataa acgaaataaa aaacactttc
    34681 gaaaaagaaa acgatgtgaa aatcaagcta gtagaaaagg acatgttcga tcagttggaa
    34741 tcattagcgt tagatgggcc tgctggaaag ggacctgacg ttatgatggc agcatatgac
    34801 cggatcggtg cgttaggaca gcaaggacat ctggcggaag taaaactggg aaatgaagca
    34861 gcttacgatg aaacagacaa agcccaagtg acttatgatg gaaaaatcta cggagaacct
    34921 gcagtaatcg agacccttgt tttgtactat aacaaagatt tagtcgatac agcaccatca
    34981 acgtttaaag atttggagaa tctatccaaa gacagtcgtt ttgcttttga gtcagaagca
    35041 ggaaaaaata caggattttt agctaaatgg actgactttt attattccta tggtttaatt
    35101 gcaggttacg gtggctatgt atttggtgat gatggcacaa atccttcaga tatcggtttg
    35161 aataatgcag gtgctgtaga aggaatctct tatgcaacag attggttcaa aaatgtttgg
    35221 ccaaagggaa tgcaagacat aaaaagtgca ggagacttcg ccagccagca attcatgtcc
    35281 aataaaactg cagcaatcat tgacggtcca tggcaagcgc aaacatacaa agaaaacaat
    35341 atcaattatg gtgtagccaa aattcctact ctaaataatg gacagcctta tcaaccgttt
    35401 ggcggaggaa aaggatgggt agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa
    35461 tggcttgatt atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa
    35521 atccctgcaa accaacaagc tagggaaaca gcaaaggcta aaaacgatga attaacaaca
    35581 gctgtgattg aacaatatga aacagctcaa gcgatgccaa acatcccaga aatgggcgaa
    35641 gtttggacag gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa aacaccaaaa
    35701 gaatccgcag atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa atactgatta
    35761 aaatgataac cgtccatttt tataaaaaat ggaacaggtg cttcagataa aagtggcaag
    35821 agcgagatgg aaaattatct tgctcttgtt gccattatct taaaagcagt ttgcggttta
    35881 gcaagtttag agggggcatt cagatgcagc aagataaaac aagcaatatc aacgaaaaaa
    35941 aaatcacgct ttgttcactt attccaggga tggggcagtt tgtaaatggc caagctttta
    36001 aaggtatcgt ttttttcgcc atattcgtcc tattcattgg tcagatgctt ctgggcggat
    36061 ttcatgcatt ggtaggattg gttactttgg gaagtatacc aatggaagat cattcattat
    36121 ttattttgat tgaaggcact ttgcaattca tcattacaat cattttcttg attttttacg
    36181 gtttgaatct tttagacgct tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca
    36241 atcggacgat gaaggaagtc atacataata taggtgatga aggttttcct tatctattga
    36301 cacttcccgc ttatcttctc atgattttta cgatcatttt cccagtccta gttacattgt
    36361 tcactgcatt tactaattat gacttcaatc atattccacc agccagttta attgattggg
    36421 taggggctaa aaactttttt agtatcttct ttttaagctc atatcgtaat actttttttg
    36481 cagtcttttc gtggaccgtg atttggactt tatgtgcaac aactttgcaa atcacccttg
    36541 gtattctcac agcggttgtt gctcaccaga aatttattaa attcaaacgt attttcggta
    36601 tcattttctt attaccatgg gcggtcccag cttttattac tatcatgagt ttttcgaata
    36661 tattcaacga tagcgtaggt gccatcaata ctcaagtgat tcctttcata aaccagcttc
    36721 cttttgtaga tatcagtgca atctcttgga aaacggaccc gaactggacg aaagtagcaa
    36781 ttatcttagt gcagggctgg ttaggatttc cctatatcta tgtgatggtt acaggaatct
    36841 tacaatcgat ttcagaagac ttatatgaag cagcaaaaat cgacggagca aatgcatggc
    36901 agcgcttttc aaacatcacg cttcctgctg tcttcctagt ggcagcgcca acatttatta
    36961 cacagtatac ggggaatttc aataatttct ccatgatcta tctgtttaac aatggcggtc
    37021 ccggaagcgt aggcggagga gctggttcta ctgatattct tatttcctgg atctataaac
    37081 ttacgactgg aacttctccg cagtattcta tggcttcagc aatcacgttg attatctccg
    37141 tcatcgttat ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc aatatggggg
    37201 attaacaatg aaaaaatttc attcgagtgc tcgattccaa aaacgacttt ctcacttttt
    37261 tacttacttt tttcttttaa tactgtcagt cattatcatc tatccgcttt tgatcacagc
    37321 aagtactgcc ttcaagtcag gaaatattgc agcttttagt ttagatcttt caagtgactg
    37381 gactttagga aactttactc ggctattcag tgaaacactt tacgggactt ggtataaaaa
    37441 tacattgatc atttctgtcc taacaatgat cgtacaagtg actgtagtaa ctttggcggg
    37501 ctatacttat agtcgctatc gttttatcgg ccgcaaatca agtttgatgt tctttttagt
    37561 gattcagatg gtaccgacta tggcagcatt gactgccttt tatgtcatgg ctttcttatt
    37621 agaagcgctc gataagtact ggttcttgac aatgatctat ataggcggtg gaattccaat
    37681 gaatacttgg ctgatgaaag gatactttga cactgtacca atagatttag atgaatctgc
    37741 taaacttgat ggggcagggc atttcaggat ttttttccag attgtattac cgcttgtcaa
    37801 accgatgctc gccgttcaag cattatgggc ttttatggga ccttttgggg atttcatgtt
    37861 agctaagttc ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct tacaaacatt
    37921 tatttctgat gtgacaaacc aaagagtctc tctttttgct gctggggcaa ttttgattgc
    37981 actaccgatt tgtctattat tcttcttttt acaaaagaac tttgttaccg gcctgacatc
    38041 tggcggaaca aaaggatagg agcagagtat catgcaaaca tttccgttaa actatttttc
    38101 cgcattacgt acgccaactc aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt
    38161 tttcttgata tttgtatttt tagtttcctt gatggtcatg cctgtgactc ttttttatgc
    38221 caatcagatc caagcgattc cattagaaca atttctatcc gttcattcgc tgatcgatga
    38281 acaaggaacc caaaaatttt ctgaacttga attatctgaa actgggttac aagcatcgca
    38341 acaaacgata gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca
    38401 atccgatcat ggaactttta ttgattttga gaaggaacaa tgggtgatcc aacaaaagga
    38461 taaatctggt atacgccgct atacgatgaa ttatagccca tctttccaac cagattctgt
    38521 acgtacgccc gaagatttcc aacgattttt agaaagagaa ttttatgcca gtaatcgtcc
    38581 aacaatcatt ttatcttata gtttaagtct tggtcttgtc ctatttgtca tgacgagtct
    38641 cattttattc ggggcttcct ttttcttgtg gatgacaaga aaaagccaac tttcatccat
    38701 tcatacattc aaagagagtg caaatttgat gctgaatgtt atgggaatag gttccatggc
    38761 agcagcagtt gtagggttta tccactttga ctttatcttg atgctaagtg tccaaacaac
    38821 gataactgtc ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt
    38881 cgaatgacaa gtttaagcga tttatgcgac aatgaatgtg aaaaaaatga aaaataaagt
    38941 agtttttgaa aaatttctga aaaaattaaa cttcttagtt gattcttttc ttttttagta
    39001 ttaacgtaat agggtagttt ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa
    39061 tcaattattt tcacgttctt tctcgctccc tgtcgaagta aattattggg acggtacaac
    39121 gaaacaatac ggagatacgg acactcctcc ccaaatcaaa atcaatatcc atgaagaaat
    39181 cccaatgaaa gagattacaa gtaacgcatc tttggcacta ggagaagcct atatggatca
    39241 tcgaatcgag atcgagggaa gtatccaagc attgatcaac gatgcttatc agcaagcaaa
    39301 cagcttttta cgaggaaaag attatctaaa atggctgcca aagaaagaaa aacatacgaa
    39361 acaaaaaaac aaagaagata tccatgcgca ttatgactta ggtaacgact tttataaact
    39421 ttggctagat ccaactttga cttattcttg tgcttatttc aatacacctg aagatacgtt
    39481 ggaacaagca caaatcaata aagtccatca tatcttagac aaactcttta tcaaagaagg
    39541 cgaaacgttg cttgatatcg gttgtggctg gggaacattg atgttcactg ctaccaaaga
    39601 gtataatgtc aaggcaactg ggatcacact aagtgaagaa caatacgatt tgattaccaa
    39661 aagaataaaa gaagaacatt tagaagataa atgccgtgta ttattaatgg attaccgcga
    39721 actaaaaggc gaaacgtttg atcatatcac aagtgtaggt atgttcgaac atgtaggttc
    39781 tgaaaatctt gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc
    39841 tttgatccat ggaatcagcc gacaacaagg cggtgcgact aatgcttgga tcaataaata
    39901 tattttccct ggcggttatg tccctggtgt tactgaatta gttgataata ttacaaaaaa
    39961 cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac taccaattga cattagaaca
    40021 ttggacaaag aattttcatc aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt
    40081 ctatcgaatg tgggatctat atttacaagc ttgtgcagct tcatttgaat caagtaatat
    40141 cgatgtgatt caatatttgc ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc
    40201 ataattgagg caaaagtact gtttaaagac tatttaaaaa gaagctaagt tttatgatgc
    40261 tccagaagtg aacttttttg tctaacttct aggattgtct ctaaagctta gtttcttttt
    40321 ctttatattt tcataataaa agtttggttc tttaattttt aaacatgaca gaaaattttt
    40381 tcttcgttat acttgtaata gaatactatt ttataacaaa ggggatcgaa tcaatgaaaa
    40441 aaactgttat ttatactagt ttatttgcag ctttgttttt agctgcttgt caatcaaata
    40501 ccaatcaagg cacatctggg aatacgtctt ccagtagcga acagcgctct tcacaggtat
    40561 cggactcctc aacaaaagca agcacatctt cgtctagcca gacaaaaagt tctagtgaag
    40621 caagtactca gtcagatatc aaagtgtctg cagctcgtgc gatcgaattg ttccaagata
    40681 aatacccaga tactgcaatt actagtttgg aattagatag tgattgggga tcttacttct
    40741 acaagataga aggtgtcgat gatcaaaaag aatacgaagc aagaattgat gctcaaaatg
    40801 aaaaaatgga gacagagaat ccagaaactc tagatcgaga tgaacaaaat ggtcaaaaga
    40861 aaaaagaaga tggtctggat gttgataaat tgatcacgat tgaggaagca gcaaaaatcg
    40921 ccgtcgacaa agtaggaagc ggtacggcaa cagattggga tttggataaa gatttaggta
    40981 ctacttattg ggaagtcaaa gtaaaagacg gcaatcaaag tacatcagtc aagatcaata
    41041 gccaaacagg cgaagtactg tcaactgaac aagatgatta agaatttctt cggaaaacaa
    41101 gagttgattt ttcttttagt catgatacac tagacaaaat aacttgtttg aaggagcgat
    41161 ttacttgagt ttagaaacga cctttgccaa tcatatcttt gccaatcctt tgatgaatgc
    41221 atctggtgtc cactgcatga ctatccagga attagatgaa ctggctcatt cagaagcagg
    41281 agcatttatc actaagagct gtacgatcaa tgaacgaaaa ggaaatcccg aaccacgcta
    41341 ttttgatgtt cctttaggga gtatcaattc tatgggactt ccaaacttag gtttttctta
    41401 ttatctagag tatgctcttg cgtatgaaaa agtgcaggaa aaccaaaatc aaccgttatt
    41461 tttttccatt gccgggatga gtgtccagga aaacttggaa atgcttgaga aaatagaaaa
    41521 aagtgggttt aatgggatca ctgaattaaa tttatcttgt cccaatgtgc ctggaaaacc
    41581 acaactagct tacgattttg aggccactta tgaaacactg aaagaagtat tcagcatctt
    41641 ttctaagccg ctaggaatca aattgcctcc ttattttgat tttgctcatt ttgatcagat
    41701 ggctgatatc ttgaatcagt ttccattgac ctatgtcaat gctatcaaca gtgtgggcaa
    41761 tggtttgtat atcgatacag aacaagaagc agtagtcatc aaaccaaaag aagggttcgg
    41821 cggcattggc ggagagtata tcaagccgac tgctttggcg aatgttcgcg ctttttatac
    41881 acgtttgaaa ccagaaatcc aaatcattgg tacaggtggg attcggacag gacaagatgc
    41941 atttgaacat ctgctatgtg gcgcaagcat gttacagatt ggtaccgagc ttcataaaga
    42001 agggccggaa attttttcta gaatcataaa agaattaacg cagattatgt cagaaaaagg
    42061 atatacgtca attgacgaat ttaaaggcaa attacgcacc atttcatagc aaagagacga
    42121 aggtcatgat tgatcttcgt ctttttttat aaaaaacact cgtctgttca ttcctgtgca
    42181 agcgtactca ttgtatgtta gacgaacttg tgggaaaata acagaggcaa aaaggaggat
    42241 aatatgaatg atgcaacaga attagcaaaa gagcttaaag aaaaagaatt tagttttcaa
    42301 gaactagtta cggatataca gaaaaaaata aagaagcaaa atcatgaatt gaatgcgttt
    42361 gtcgcgcttg aaccattcga gagtaattcc cacgagctat tgattcccca gtcagaaaaa
    42421 gggccattgg ctggtatccc atttccttta aaaatgctcg gtcaagaaaa aaagggatgg
    42481 ctagctactt caggatctcg tttatttgaa acacaccgag cttctcatac atctaattat
    42541 gtgcggcaag cagaagcgat aggtctagtt ccttttggac aaaccaatgc gccagagttt
    42601 ggtttcaaaa atattacaga cccagtcatc tatggcccag caagaaaccc ttggaacctt
    42661 gaatgtacac cgggcggatc aagtggagga gctgctgctg cagtttcatc aggaatcgtt
    42721 cctttagctg gtgctagtga tggcggtggt tctattagaa tacccgcttc gttttgcgga
    42781 ttgattgggc tgaaaccttc gcgagggacg atgccagttg gtccatatgc ttggagagga
    42841 tggcaaggag ctgctattga tttcggcttg acagtttcta tgagagacac ggaggcttta
    42901 ttttatggga tgagaagtat ccattccggt gcgccatatc aagtatcgcc agttgagtgg
    42961 caaacacatc caagaaaaaa acggttgaag atagcttttt gtgttgattc accgatccac
    43021 tcacagatta gtgaagaggc agtacttgct gtaaaaaaag ctgtagattt ccttggaaaa
    43081 gaagggcatg atttgacaga gattccttac ccactagatg gtcgtaaact gatcacgtct
    43141 tattatcaga tgaatggcgc agaaacagca gcaatgatcc gctcgattga aacaggcatc
    43201 cagcgagctg tcagaaaaga agaacttgaa cccatttctt ggactttgtt ccaatatggt
    43261 cagaagctct ctgccgctac ttacatcgat tctctgcatg tatgggatga agcagcaatt
    43321 gtcatggaaa acctacatca agaatacgat ctattccttt caccaacgac tgcatttacc
    43381 gcccctaaaa tcagcgaaga tttgcaaagt gatgcgataa gagcacagat ggaacacatc
    43441 agtgattgtt ctgaagtaga aggtttagac gttgtttctt ccatgtttga ggagagcttg
    43501 aagatcacac cttatacaca gttggctaat ctgactggac aaccagcaat cagcttgcct
    43561 actcatttga caaaagaaaa catgcctcta ggaatccaat ttatggctgc cagaggaaga
    43621 gaagatttgc tatttcaaat cggctatcta tttgaagcaa atcatcagtt ccatttacca
    43681 aatccatgga aatagcagaa acaaggagaa gaagaatgaa gaaaaaaaga ttgtttgctc
    43741 taataactag tgcctttttt attttaagcg cttgcggtac agctgccgct aatcaggaag
    43801 ataacagctg gagtaatgta gaaaaaaaga aagaattagt agtagcgact tctggcacac
    43861 tgtttcccgc atcttattat aatgatcaaa atgaattagt tggttatgat gtagatttgg
    43921 caaaagaggt ggctaaacgg ttaaatgtca aaatctcctt taaagaatac aacgtggatg
    43981 gacaaatcac ttctgtttca aaaagagaat cagattttgc tgcgaacgat tttggtatca
    44041 caaaagaaag agaaaaaaaa ttctcccttt cagagacttt caaatattca tttgacagta
    44101 tgatcgtacg aaaaaaagat gattcaggaa tccactcact tgaagatctt aaagggaaaa
    44161 aagcagctgg cgaacccaat actagctata tgcgtttagc ggaaaaacac ggagctaaat
    44221 tagtcacata tgacaatgcc acgaatgatc agtatttaag cgatgtagca aatggtcgaa
    44281 cagatgttat tctaaatgat tattatctgc agaaaatggc cgtatctgct ttaccagata
    44341 tccctgtaaa aatactggag aacgtttatt tcaatgaaaa cgaaagtggt tttttattga
    44401 aagaaggaaa tgatgctctg aaaaagaaaa tcgatggcgt attaaaagag atgaaagaag
    44461 atgggacgac aaagaaaata tctgaaaaat attttcaaac tgatgtttca gtcaaaccga
    44521 aagaaacgat ggctgagtcg gtgagtgagt gatgtacttt cctctaattg atttttccct
    44581 catgtggact tcacttcctt tcgtactgca aggcttggta tacacattag ggattggctt
    44641 cgtgtcgttt cttttaggaa atctggtagg gttgcttttg acagttttag gtcttttgga
    44701 ttggctgcct ctgaatgtat ttattcgttt ttatttatcg ttctttagag gcattcccgc
    44761 actagtcctg ctgtttctgt tatattttgg gttaccttat caattaagtg ccttaacggc
    44821 ttcagtcatc tgctttacga ttaccagcag tgcatttatt ggtgaaatct atcgaggatc
    44881 actagcaggc gtttcttcag gtcagtggga cgctggttta gcttctggtt tttctttctt
    44941 tggggtattg aaatatatcg ttttgccgca agcttttcga atctcagtac cggcactcag
    45001 taacgtagct atggatctag tgaaaggtac ttcgttagca gcaacaatca cagtgccaga
    45061 aatatttcaa aaagcaaaga tcataggcgg tcggacattc gattattttt ctctctatat
    45121 tttagttgca ctgatttatt gggtcatttg tatcgggatc gaaaaagtgc aacagtattt
    45181 agaaaaacgt tctatgcatc agtcaatctg aaaaatagaa atggtgctag cgtggctggc
    45241 accatttcta ttttttgttt cttgtatatt ctgcctagta ttttaaaacc atttcatgta
    45301 aaatgtaaat cgaaaatatg ttcggaggta gaaaacatga agaccccgct aaccatcgaa
    45361 atagaatcct cgttatacca atattgcatc gagcaaggcg gcttggttgt agaagaagtc
    45421 acgatgcctg atgaccaagg aattgtagat acgcttagct gcttgacaaa atttgatgga
    45481 agccgagaat ggcgatgcta tgagctgaaa gtgacaaaag cagattttcg ctctacagcc
    45541 aaactgtcat ttgttggaca ttataattat tttgttttac caagtaaact atatgaagaa
    45601 gtaaaaactg aaatccctac aggaataggt gttttagtgt atcgtccgta cacggttgaa
    45661 gaggagatgc ctgcctctgg tacatttctg attgcgaaaa aagcagcaaa gaaagagctt
    45721 gctgtaccgg aagaagcttt gacaaaccgc ttcatggctt ctttattcag ggaagtaaga
    45781 aaagcaaagc aaatggagcg aggcgtaaaa tattttccaa cagatcaatt gtacaaagaa
    45841 ttgaaaagac gttcagaaaa tcaagatcca ttttctaacg aacgatatta tgaacggttt
    45901 ttagaggaaa tagctagtca ggcaatcaat gagttgcaag aagaagttat cgcgcttcag
    45961 catgattatg aatatttgag gcaacaacag cagatccgtc ggttgcctac agagccattg
    46021 gagtgaaaaa tatgtactat ccttatttaa gaggaaaaca atttgaccta ttagcattaa
    46081 aagaagcact gtcgcgagga ttgctctcca ataaaatcca accagtgatc gaaccagtac
    46141 gtgattccgc tacgcttaaa aatgtgatcg aattatttca aaaaaagcac catcgaatcg
    46201 ctgtgatcca aaatccccaa gtaggacaat tcaaattatt cgatcagcat gtgcacagtt
    46261 ggacagtcaa agaaaatagc tctgtcgtcc ctgcacagat cttaacgcca gaaaatctca
    46321 gtgaagtact ggattcacct ccagcgtttc ttgttttcga tggacagcac tacccaaaag
    46381 atacagaggt gtggaaacag ttggcaggag ttgattcgaa atttttgata ccagatacta
    46441 gtcgctttcg catctggctg cccgaaaaca aaattgtgat ccgtgactct tttcaaacga
    46501 gaaagcatgt tgaaagttat gcagataaaa cagatgactt ttttagtgat gactatcttt
    46561 ttttccacgc agacggatat attggatttt ctgatttcac gatcgaaggt agccgttatt
    46621 tcgataaagg gttccctagc cgagcgcttg ctatccatct aacgtatatt gatgcttacg
    46681 gcaatatacg cgtgaaacat tttgtctctg acagtaacga ctctgctaaa gaccaagcat
    46741 tgaagtttct tgaagcagga gataaaatga aaaaatggat catgcgtcac catcatcaac
    46801 tcttgattac ttcaggaatg attgaattat tggctcttta ccagcaacaa aaattccctg
    46861 gactgggagt gttgaaaaag tggtcactta tgcatcattt ggaacttatt agtcacctgc
    46921 tagatcatcc aaaagattgg cttaaatatt attcaaaagt tcaggaacta tatgaagtga
    46981 tccaatgatt agataatgta aatgaaaaag gaatagaaaa gaggaaactg gatgtatatt
    47041 cggcaaacaa ggaaagaaga agtagaagaa gtggtagaaa tcattaatgc cgcagcggat
    47101 ttcattgctt cgcaaggctc tcctcaatgg caaaacgggc agaaaccaac aaaagaaacg
    47161 attttgaacg atattgaaag aaaagaaagc tatgtattaa tagtggaaga tcaaattgct
    47221 ggaacagctg cattagtctc aagcgtggat cccgtttaca caaaaataga tggtagttgg
    47281 aaagaatcaa ctggtcctta tttatcgatt catcgtgtcg ctttagcaga aagtactcga
    47341 ggaaaaaaac tagcaaaacc gttcttagaa catttgttga cgattgcagc cagcaaaaat
    47401 atccaagata tccgtatcga tacttatcca gctaatgaac cgatggaaaa gaccatctat
    47461 tctgctggat tcacttatca agggatgatt gaatttcctt ttgaacacgg cgaaagaaaa
    47521 gcatatcaaa taatcatcaa ttgactataa aatcatctga gcaaagataa agacattaac
    47581 actactgaaa aaaacaatca tatgatagcc aagaggttgt aacagaagtg gccagcttca
    47641 aaaaacaaga aagaatttcc gaaaatgctt ctcaaatttt tgtggaattt tagcgtattt
    47701 tacgaaatag ctgctttctg aaactccctt catcgagagg tcgtgacata gcttttgtca
    47761 cgacctctcg gcttatccta cgagtattat tcgatacatt tatatcaata atcctttttt
    47821 tattttatct gcagcttctt ggaacgctcc atcgtttgac acgactaaaa gtgaggggat
    47881 agctttcaaa cgtttcaact gtgctaaatc ttctacataa accgccagtc tggctgaaat
    47941 ctgttcagat gaatctccac gttttttcag gcgcgattgc aatgtttctt tagagatcgt
    48001 aataaagata ggacggacta ccgtcccgaa atactcatat aaatgccaaa aaccatttgc
    48061 tgtcaaaacg gcgtaacaat ttcctactgt cagtttcttt ttaatttctg ctttactgga
    48121 accatattta tgttgagcat attggtccca ctctgcaaac tcatttccct tgatcatctg
    48181 attgaatgta ttgtcagaaa caaaataata atcctcttga tctttttccc caggtcttgg
    48241 tgatcgattc gtgtaagtaa tgatcttttg ttccggctga aaaatagctt ctgcgagtga
    48301 agtttttcca gaaccagaag gaccgataaa tacatagcaa taattcattg tcatttctcc
    48361 tttgatgatt gaacaagtga aaaagctttg gaaaatattt ccaaagcttt taaaagtaac
    48421 tttgcttttt tgtatattat accagcaagc cagtcacaat agcacttaaa aagctgacta
    48481 aagtcgctgt tagcaaaatt ttcaatccgt gttttgcgac aagatttcct ttttcttcat
    48541 ttaatccctt catcgcacca gaaatgatcc cgatagaaga gaagttggca aatgaaacga
    48601 ggaagacaga tataattgct gttgtacgct cagtaaaatg gaaattacca tttgctaatt
    48661 ctgtcatagc aacaaattca tttgtaacca gtttagtcgc catgatacta ccggcatcca
    48721 ctgcttcttt ccatgggatt ccgctgatga aggcaagagg ggcaaagatg taacctagga
    48781 tctcttggaa agtgatgccg aatatcccgt ggaagatagc attgatcatg gcaatcaaag
    48841 caacaaaacc gataagcata gcagcaaccg tgatcgccac atggaaacca tcaagaatgt
    48901 attctcccaa catttggaaa aatgtctgtt ctttgttttc ttcaatgatc agctcatctt
    48961 ctttttcttc taatacatag ggatttacaa ttgaagccag aatataaccg ccaaataagt
    49021 tcaaaacaag ggcagtgatc acatatttag aatcgatcag tgccatataa gatccgacga
    49081 tcgacataga aactgtagac atagccgata cactcatggt gaacaaacgt ttctcagata
    49141 ggaagggtaa ttcctttttt atggaaataa aaacttccga ttgtcctaaa atagcagaag
    49201 ctactccatt ataagattcc aatttgccca tcccgttgat tttacttaat cctagaccaa
    49261 cagctttcat aaataatgga agaatcttga tatagcgtag aataccgata atagcagaaa
    49321 taaatacaat tggcatcaat acggaaagaa agaaaggtgc acttccttta tttgctacac
    49381 cggcaaaaac aaagtcaaca ccttgcccag caaaagcaag aagatgatca aacatttttg
    49441 ccaatacaga aacaaccgct gtaccaaaag ttgtacgtaa taatacgaaa ccaagaacaa
    49501 gctgtaaaac gaacatcaca attagtggtt tcaatttgat tgcttttttg ttactgctga
    49561 tcaaaaaagc aagccctaat gtgacaaata aaccaataat acctaataaa taactcaaat
    49621 aatcactcct attccaaatt ccgttttatt ttacctgttt tgcaaataaa atactaatct
    49681 ttagtgaaat tttcattact tttttagagt gaaacgcatt cattttccat tagaaaataa
    49741 agcgaacaaa ataaaaggtt taaaaagtgt aacgtcttag taaagtctat aaaaaaacga
    49801 aactatcgat taagctaata gtttcgtttt caacatttat aagtaaactt tttctattgg
    49861 taatatagat tttcggaagg gtagacaggt gcgcaggtaa tatcgattcc tagttttttc
    49921 aatgtttgtt catcattttt attgaccatc acagtagagt gggcttgtgc tccctcaagt
    49981 tcagctagtt tatcataagc aacttgagcg attggattcg ttactgcact gattgataaa
    50041 gcgatcaaga cttcattgat gcttagtgca tccaaagagg aatgaagtgt ctttgatttc
    50101 aatccttgta ttgtttcaag aactaatggt gacaataaag gaatgtcatc tgcgatatgg
    50161 gctaaatgtt ttactgcatt taagataact gccgctgacg catccatcaa tgaacttgta
    50221 cgcccggtaa tgatgacttc atctggtaat tcgattgcaa tcacagcaga aggatctttt
    50281 gtaggacttt gcgcttgaat cttatctgca tagtcatggg cagggactac cacgtttcgg
    50341 tcttcaggac gtaaaccgac ttcttccata atcagtttga ttcgattaac tgcttcttcg
    50401 tcgatcaatc cttttttgaa gtcgcattct gtttggaaat aacgacggat gatttcttgt
    50461 ttagaggctt cttggacaac ggtatcatcc acgatcccaa atcctacacg attcacaccc
    50521 atgtcagtag gagattgata aacagattct ttaccagtaa ttttttcaat aatacgtttg
    50581 attacaggaa atgtctcaac atcccgatta tagttcacag ctactttatt gtaggcatca
    50641 aagtggaagg aatcgatcat attgacatct tttagatcga ctgtggctgc ttcataagca
    50701 atgttcagcg gatgtttcaa cggaacattc catactggga aagtttcgaa cttggagtaa
    50761 ccagctgcat gtcctttttg gctttcatga tacagttggt tcaaggaagt agcgagcttt
    50821 ccacttcctg ggccaggagc tgtcactaca acgattggtt tagttgtttc aatatactca
    50881 ttttttccaa aaccatcttc tgagacgatt ttttctacgt tgactggata gtcttcgatt
    50941 tctgagtgtt tatagacctt gatgtttcgt ctttctagtt tattgataaa gactttcgtg
    51001 gcaggctgtc cactatagcg agtgataacg acactgttga ttaataagcc ataaccacgt
    51061 aattcatcga ttaaccgcaa gatatccata tcataagtaa tcccataatc accacggatc
    51121 ttattacgtt caatatctcc agcatagacg caaatcagta tttcagcttg atctttcaat
    51181 ttttgcagca atttgatttt cgcatcttct tcaaatcctg gaagtacacg tttcgcatgc
    51241 ttgtcgtcaa ctagcttccc accaaattct aaatataatt tgtcatagtg gttcactcgt
    51301 tccaaaatat acgctgactg ctcttcaata tatttttctg aatcaaaacc aatttttttc
    51361 actaggttcc ctccttaagt actaaagcat tttttcattt ttttgaggat tcgtcaactg
    51421 gaagagcgaa attcctcaaa aaaacaaaga aaatggttta aaccaacttg tctagatagt
    51481 tattcattgg tatgatagtt tttgataagg aaggtgctac atgaaaaaaa gacagaaaaa
    51541 gaaaaacgca tataaacact atatccgttc gatttttacc ggttatgaaa gaatgcttga
    51601 agatcccgaa ttggaacaat tgacgtttac ttatctaaac gaagaaacgc agctaactcg
    51661 tgatgagcat cagcgcattc atttcacaac aagagatctg cctagtaaat aaaaaataag
    51721 ataaaggtca tcggattcga ttctgtccta tcagatggaa agactagttg atcgaaaaaa
    51781 aggctgtacc aaattttggt gcagcctgtt ttatggagca ttgcccgctc ttttttataa
    51841 caatttttta cagaaaatgg tactattgaa gtattaataa gtgaaaaaca gatgagtaag
    51901 aggaggcaag tagtatgaaa gagccagata caaatgcaaa ttatgagcca gacgaactag
    51961 aggagacgaa tgcggatcag gatacaggac aagaatcgtc ttctttttac gatatcaaag
    52021 aaaaagcaag catgaatctt tcccaattat tagaagactt acaggctttt gaaaaagctg
    52081 tccgcgaaga agatatccct gagatctacc gtttatacaa tggccgattg aatgaagaat
    52141 taaaaagaag ctcaaatgaa aatcacgaga tcgatcaatt gctgatgcgt aagatccatg
    52201 atcgtttttt acaggaattt ccttttatgg aacaagtaga aaacatctcg ccaacgatga
    52261 gctattacaa aatcggcact tattaccatg atcggcccac ggtcggtatt gatgcaagtc
    52321 tgccagaaat ttttgttttg cctaagatcg atgaagagtg ggagaaatat tcccaaccgg
    52381 agtcaacgga ctatgacaaa aaaatcaatg agctagacgc aaaggtgatc actgctcaga
    52441 cagaaattga acgtttagat gaacaaataa aagaaatcaa tcgacaaatg actgatttga
    52501 acgacaataa aggattcttg aatcgtaaaa aaatcgagga agaaattcaa gaattagaga
    52561 agaagaagca agtactatct aatgaaaaat taggctggct tccttatatt gagacgcctg
    52621 aaacaatcca gcagcaaaaa gaagcattga agcaagaagc aagagcagac cagcttcgtg
    52681 cagccatcgt agaaaaagaa caaaggcaaa tcagacgcta tttcggtagc aaagagggat
    52741 tcggtcaagc aatccatgaa ttcttgatga attatcttgg caatgagaat cctaataatc
    52801 aatctaatga aggaggttcc gagtatgaat gaacacgatg aagcagaatg gacaaaaaat
    52861 gaagaacaaa cagaagatca tgaagaaacg aacacttcat tggaagaaca aacaagtaat
    52921 cctctggatg acacagaaga aatccctatg ctagaggaaa caaaaataca cgaaaaagaa
    52981 aaagtaactc cgacgaatac gaatactgca gaaaacaccc atgcttacga aataactgaa
    53041 aatcccgggt atttagaagg aaaagagcaa gatcatcaag atatcgtcag tttgattgaa
    53101 acagcggaag cagaattagc ggatttacgt atgagaaaag atttgatcga atcagatttt
    53161 ccacaattat tagaatcata tgatcgtttt atattgaatg aagaaccaat ctccacgatc
    53221 ggaaagacaa gcctgatcga atacttcacg tatgaattac tgaaaccgtt gaatgatatt
    53281 ggtctggaac ggtcaaattc agcttatgac acatggaaaa caagacattt ttcgatcaat
    53341 tatacgttga atggacaaaa cgaattagtc ttttcctttg tattaccgac catcgatcaa
    53401 cgataccaag tggaatcgat gagtctccta aacgtatcac cagagacaat ggaaatcaat
    53461 gtccaagatg accgggtgct ttctttgatc cgacactggt cagtggatcg agtattctct
    53521 gcagggcaga tcacgatatt caatcacaaa ttgaatcaat tattagccca tgcaagaaca
    53581 cttggtttta ccgttaatca gacattacta gacaatacga agccacttcg tttgaatctt
    53641 cagagcgaat ttgaattgac gaatgaagta ttggatgata tttttatcgt ggcaatgaaa
    53701 aatccatcct acgatatgga aaagatcaac gaaactactt atcaagtacg attagataaa
    53761 ggacagtctt taacgataac aacaaacgaa aaagatcaaa cagtcttgtc gatctcatct
    53821 ggagactacc cacgatctgt cattgatttc tttatcaatt acgaattctt ggtcccatta
    53881 atggtgagaa agtcctgatt ggataagttg gattaccaga tgtcattcag ataattctgt
    53941 tccaaaggac ttgcggcagt tatccagaat aattgtcaca agtcttttct gtatgtacta
    54001 aatggacgtg aataacttgc tgatgaagga gggatttcat taggaatgtc cacaaataaa
    54061 atagcacagc ttagcttatt gtctgctgct tgtgtagcag gtaggatcgc ttttcaattt
    54121 attccgaatt tccagccaat gactgctatt tttttattta tagtacttta cttaagctta
    54181 aaagatgcgt taattgtcat gagtctttct attgcgatca gcagttttta ttttggtgtt
    54241 ggaccatggg tcatcggcca atggatcagc tatactgttg ttctgagttt gttttcaatc
    54301 gtctgcttga gaaaaacagt gcaaaggaat ctatggttaa agggagtctg tttttttctg
    54361 gcgggcatgg tttacggaat aggtatgacc gtttttgata cgctgttata tcgtttgcct
    54421 caaccttgga tctattacct tcaaggggtg tcgtttgatt tgatgcacag tataggcaat
    54481 gttgtgttct ttcttgtttt tctgccagtc gtcaaacgtt tttacaatca ttcaggagga
    54541 aaaaatgaaa aaaataattt atagtttgct tgcaatgagt gtcagtatac tcattttgac
    54601 aagttgcagt acaacctata cacaatcggc ttccaaccaa aaggaggaag taaaaacatc
    54661 gcaaaaagca acaatcacgt tacaagaaaa tggtcaaaac ttttcggaaa aagaagtgtt
    54721 cttcaaaaaa ggcgatgatt tactgagtat tttgaaacga aattttgaag tcaaagaaga
    54781 taacggcttc atcacttcgc ttgaagggca ctcacaggat gagaaaaatc aactctattg
    54841 gatgtttact gtggacggga aaagtgctac tactggtgcc aaagagatca aattgaatga
    54901 tggacaatcg gtcattttca atttgtctaa actataagtt tcataaaaaa ctgttaaagg
    54961 gcgaatattg ccataattca gtgagttcag ttgatgaaag aaggaaaata acatggaaaa
    55021 ttttaaaaaa agcggaatgt tttccgtaat tgctgctcta ggggctaata ttctagttgc
    55081 tatcagcaaa tttgtcggct atgcaatcag tggcagtgcc gccatgctaa acgaaagcat
    55141 ccacagtatc gttgattgca gcaatcagat tttgctgtta ttcggtgata aacaagccaa
    55201 taaaggacag agcgagttgc atcaatttgg tgaaggacga gcaaaatact ttttcagtac
    55261 aatcgtcgca atgatgcttt tcttcggcgg tggggcactt ggggtgatgg aagcttttga
    55321 aaagttgacg catccatccc atgaagtggg taatccgatc attgttatag caatactgtt
    55381 atttggtttg gtaatcgaag gaagttcgtt acgcgtggca atgaaagaaa tcaaagaatt
    55441 gaatactgaa aaactttcca cgatgcgctt tttgcgcgaa agtcgacaca gtgaaatact
    55501 gattattttt acggaagact tgtgtgctgt aatcggtttg gtcttggctt tagcaggaac
    55561 aatattgact tatgcaaccg ggattgctgc atttgatgcg atcagcggat tgctgatcgg
    55621 tttcttgctg atgggagccg ccattttcct agcaaaagaa ttttatagtc tgatcatcgg
    55681 tgaaagcgtg acagcaagcg atttatcaaa aatcaagtta gcttttgaac gtcctgagat
    55741 cagtcggctg atcgatataa aaacagttca tttaagtcca acggagattt tagttgcagc
    55801 aaaagcagat atcgttggta acaaagagaa tgaagcttac tcggtcatca atgatattga
    55861 aaaaaatatg cgtcagtctc ttcctgacaa gaagatgtat atatacattg aaacagataa
    55921 atatgaccca aattattctc gtaaataaaa cgtttattca tgaattgaag caaaaatgag
    55981 aaaaatataa tcttgttttt aaataaaacg gctacaattt agcgaattta tgttacaatg
    56041 agtccgctgt ttatttgttg taattaaagg agatatttta atgaacaaaa agaaaagtgc
    56101 gccatggctt caagctttgc atgcagtgat gccactttgt ataagctata taccagtagg
    56161 attagcttgc ggagtattgt tgcaaaaagt tggatttgat cctctcttat caggactgtt
    56221 atcgattctg gtcttttccg gtggcgcgca gtttttagtt gcatctatgc ttacgacgca
    56281 agcatcattt gcaacgacat tattgatggt tttcttttta gaattacgct atacattatt
    56341 aggagcaagt cttgccggtt ttatgaaaaa agaaaagcgg acgtttttgg ctgtcttttc
    56401 tcaatcactg aatgatgaaa actatgcggt gaactactta aagttttcaa ctgacccttc
    56461 ctggaataaa agaaaggctt tatatgtcaa ttggttctca atgactgcat gggccggtag
    56521 caatatgatc ggtaattttt tcggctcggt gattcgagta gatgctgacc ttgtccattt
    56581 tgctttgacg gccatgttca ttttcatgtt tatcatgcag atgaaaagcg cactactgat
    56641 ctttacaggt ttattctcag gcgtattagg ggtcgtattc atggtattat tccaaaatac
    56701 tttcggattg attgcagcaa cagtcattgc ttcatttgcc ggatttatgc tggagaaggc
    56761 attcaaaaaa gaaaaagcta agaaactaag agaccgcggt aaagatgtca atgagccgct
    56821 cttcaacttc ccggaacagg aggccaatca ccatgactaa actatatttg ctacttttag
    56881 ttgcttgtct gttcatcgtg gcatatatcc cgcgcttgtt cccgatgctt tattttactc
    56941 atcgaaaagt gccatcctgg ttcagtgact ggatgaaata tgtaccggtg gcattatttg
    57001 cggcgttagc ttttaaagat gttttcatta ctcatgaaca tctggatatt gcttggaata
    57061 tcaaaatagc tgcaatgatt ctagtagcag gcgtggctta caaaacacgt tcgatggcgt
    57121 tgtcagtttt gacaggactt gcgtctgtct ttttgctgtc tatgctttaa actgttttat
    57181 tttattaaaa acagagattg cgacataagt tgttcaaact gatctatccg aactgcattt
    57241 gcaacagtca attctggatg caagtttatt cgtagggata aaaaagatta gtgttggctt
    57301 atgatgcaag ctctttttta ttttaggaat tagagaggga tttgtccttc tatgattttt
    57361 tgctataata gggaagatgt ttattttatg aaagaatagt tgagggaatt taaatgaata
    57421 aaaaattgat gcaaggaaca ttttggctaa cctttgctaa tcttctatgt aaagttttag
    57481 gggtagtcta tttgattccc tggctaagta tgatggggaa caatcaagat ggtatgcttg
    57541 ctacgacatt gtataatgtt ggctatcttc cttatggatt gttcctgatg cttggtacag
    57601 tcggatttcc aaatgcgatt gcaaaaaaag tagctgtagc cacaaaagaa ggagataacg
    57661 ctgcttgtcg gctgattttt agaagtacga tcaatatcat gtttgtcatc ggtatcgcct
    57721 ctgctgcact gatgtattta tttgctcctt tactagccgg aatcagtccg attgctaacg
    57781 ttaataatgg gatactagct atcagaagtt tatgcccatc tttgattgct atcccaattc
    57841 ttagtgcaat gagaggatat ttccaaggaa aaaatgatct gcggccttat ggaacttctt
    57901 tgattatcga acaggctgtg cgagtgatcg ttatcttggc tggtacttat tacttgcgcg
    57961 tattgactga cggaaccata ttagaagctg tattgatcag tacagtcgct tctttcttcg
    58021 gtgggttagc tgcgattatc catatgtata tcgtcggacg cagaaaagac ttcttcgaac
    58081 ttaaagattt tttgatttcc agccgttatt tcgaaagaga aaaccgatct gcctctgtct
    58141 ctatcattcg ggaaacacta ccgtttattt ttgtcggctc agtcattact atcgttcaaa
    58201 tgatcgacca agtaacgatg aaaccactgc ttcacttttt ccgtccagag atcgcagatc
    58261 agcaactgga attcttattc agccgtgctt ctgtcaatcc aaataaattg acattgatcc
    58321 tgatctccat ggtaggaaca gtagctataa gcagcttgcc aatattaagc acgatgaaga
    58381 aaaaagatcg gatacaaatc gaaaaaacag taggagatag tttttcgatt gcgttattga
    58441 ttcttcttcc ttcattgact ggaatgtctt tattagctgg accactatac acattgtttt
    58501 ttggctatga tcctgaaagt gtcggatatt tccaaatggc tttgctagct tctttgtttt
    58561 tctctttatt cacgatccta tctacgatgc ttcaatcttt gaatcaccat cgttttgcga
    58621 tccgattaac tgtagaagca attatcctga aagtcatctt ccaagtaatc ggattaggat
    58681 tagttggcgg atacgggatg agcttatcaa atggcttagc attcggtatt gtctttgttc
    58741 gcggctatca ctttatgtgc aaagaatacc gaatagcacc tttagcaaag atcagcaatt
    58801 ttttcttaaa aactttccgc tccaccctga ttatgcttgc agtatgtttt gccgttttct
    58861 ttttgctgaa tcagcgattg tcaatggaat caaaaagcta tgcaatgatt tattgtgtgg
    58921 ctgtaggaag tattggcggc ttagtatttt tattttctca attcggaaaa aatgggtttc
    58981 gaatgttgaa aaatgttaaa catcatagca gaagcaaaga ataggttaac taatcgtttt
    59041 ttgctgtcac ttgaaaaacg gcaactcgta tgattacgct tgtcgttttt ctattttcca
    59101 attttagttt catatctaat cttacttatg atatagttat aaggtctgga aaaattcttt
    59161 gaaacgagga aattaaacac atgaaacttg cagtagttac agatagttcg gcatatctgc
    59221 cggaacgtat caagaaccat cccgacttat tcgttattcc aatccctttg attatggatg
    59281 ggaaaattta taacgaagga atcgatatcg aagcggatga atattatgga cttttaaaaa
    59341 acagtaaaga ttttcctact acttcacaac ctgtcgtagg ggaagttttg ggtttatatg
    59401 aggaattgaa agagaaaggg tatgacacga ttttaagtat ccatctttct tcagggattt
    59461 ctggctttgt caacacatta tttgcgatga aagatgacat cagcggagta acggtcattc
    59521 cttatgactc taagatcact agtatgccga tgggacacat ggtagaagct gccttagact
    59581 taaatgatga aggtcagtcc cttgatgaaa tacttgcaca tatcgatcga atccgagata
    59641 atacctacgc ttatctgatt gtagatgatt tgaacaattt agtacgagga ggacgtttga
    59701 caaatggtgc agcgctgatt ggcagcttat taaaaatcaa accgatcctg acattttctg
    59761 aagggaaaat tgttttattc gaaaaaatcc gttcaagtaa aaaagcattt gctcgagctg
    59821 aagaaattat tggtagaaga aataacgaaa tacaaccgcc agtcaaactt tacgtgatac
    59881 atgcaaataa tttagaagta gcgattgcgg agaaagagaa attgcagaaa aaatatccaa
    59941 atgcagaaat cgaaattggt catttcggac cagtcattgg tacacattta ggtgaaaaag
    60001 ccatcggcat tgccatttca gcgcaataat tccttttatt caaaaaacat accaaaaata
    60061 ttccaacatc atcttggact ttctacatgt tactaatgag cgtgtaaaag aacgagatgg
    60121 tgtttttatt tctatcaatg aagctctttt tctttgcaat cctcacttca atcctctata
    60181 atgtcgcata tagtttagta aatgagtaaa ctactaattt acttatttac taaaaataaa
    60241 aggatgagga gttaaaataa tggaaatacc aacaaattta aaacataaac cagtaatcgt
    60301 tgtagaagac tatgataaag ttgatggaag aaatgcatta aatacggatg caaaagggct
    60361 ttcactgggc cttgctcagt ggaatgatcg tggaaaagtc gatatctcag gcaaggtatg
    60421 gcgacatact ggagaaaaat ggtcacgaca gtcggaagaa ttaccaatca cacgtatttt
    60481 agatttagcg atcttagctg cacaaggaag tttatacttc caagatgctt atcgttatga
    60541 aaaattttat gatccagaaa atccagtcgt agacatcatt ggattacaag ggaaccgaat
    60601 gacggtagaa gtagatacca aaaatccaaa gatcgatgaa gacatcattt tgtattacga
    60661 tacactacaa aaagacggag aactgattgg ggaacgattc cgtattttaa aacgtctttt
    60721 agatgagcta ggatattaat agacagagat gatcaaaagg ggaagagaag catggagaat
    60781 ttctcactaa cagaaaaccg aaccttttca cggctagaaa agcaaatgat ctggaagaaa
    60841 ccgaaaagcc atcggacaag tgcagaagaa tggcggatcg cctccgaaat caaagggaat
    60901 tggcaagatc ctgaaatgaa aatcagtaac gtacttttgg aaggagatgc cgggtcgggg
    60961 aagacacaat tagccaaagc actatctgct gatctgcaac ttccctatac aaaagtgacc
    61021 tgttttgcag atatggacaa atcagatgtt ttcggagcct tattacctgt agtagattct
    61081 aataaggaac aagaccaaga attactagaa gctatttacc aaacagatac acttgaagct
    61141 gtactgacac tgatccagaa ccattacggc attgatcctt tttctgctaa agaaaaatta
    61201 gcagagctag ttcaaaggat cgaagctgat tatccagatg caatccatta cagctattac
    61261 ccttctgaaa tcgttcgagc gattgaaaaa ggatatttat tagagattca agagccgact
    61321 gtcatccgag atgcctctgt tcttgtggca cttaactcag cgctcgaacc aaatgggatg
    61381 ttgaatttac cgacaggaat cattcgtcgc catccagatt gcgtcattgt gatcactaca
    61441 aatcgaaatt accaaggaaa tcgcccatta aatgaatctt taagagatcg gatgcaacat
    61501 gcggaaaaaa tggatcttcc tgccttagaa gtcatggcag aacgtgcgat ggcgaaaact
    61561 atgatccaaa aacaagaact tctcttaaag atggcagaga ttatccgttt gttggatgaa
    61621 actgcaaaag ctaacgccat caaaggtgta gcaggaatgc gttcttattt ttattgggca
    61681 aatacctata agcaaggaca agatttactc cagtcgattt atccaaaagt tttgtataaa
    61741 ttatccactg attcagatga attggcaatt cttgaacaag ctttgtctga cagtggattg
    61801 ctactggaac ttcaggacat attgagaaaa gaaaaatggg gtcatcctca atctgagcat
    61861 acaaaaggaa gaaccattag cgccgaagaa gcaaatgaac gaaacatcac tgaaaatgct
    61921 gaagaaattc tgcgcttaga tgaaaagaaa tcgttgtctg ctgaagaacc aaatgaggga
    61981 gaagagaaac aagaagaaac aatagaaaaa aacgagattc ctcctcaaat gcaaaaagaa
    62041 cgcagtagcg atatcgaagg aaaaaatcaa aaagaacaac aaacaggaga tgattctcaa
    62101 gaaatgtctg cttctgacat ggaagcacat gataaggaaa tcaagaagca actgaataaa
    62161 gaagcgcgac aaatcatgaa ggaaacgatt catgaaaaag aaggtctcat cgttcaccga
    62221 ccagctttcc aaggaaaaac gccggaagca cgtgagctac acatgcaagt aatgccaata
    62281 gtagaatcac ttagccggca aattttagag ttactggata atgaacaaac agagacgtac
    62341 caaaaaggaa aatacgaagg tcagcggttc aatgcaagca aagtagcata tggtgatttg
    62401 agaaattttg acaaaaagaa cccgccacat gagcaacctt ctttagcggt agctgtacgg
    62461 atcgatgaat ctgggtcaat gatacgggat gatcggatcg aagcggcaaa aaaagcagcg
    62521 attgccattg ccgaattttc taagaaagtc gatatcccat tgttgattta cggagataca
    62581 gcagaccgtt cgtcaagaga aaagacttct ttgttttctt ataaagaatt tgaagacgga
    62641 tttcaatggt taaatgaaaa attagtcact atgaaaccaa ggcaaaacaa tcgtgatggt
    62701 gctgcacttc gtttagcagc agaaaaatta aacagacaat ccgcaacaac caaactgttg
    62761 cttaatatta gtgacggtca gccaaaagcg ttgccggatt atacaggcaa aaaagcaaaa
    62821 gaagatatcc agtctgtttt gaaagaatat gaacgtcaag gaatcctatt tgtctccgca
    62881 gctattggcc aagacaaaga agaaatcaag tcgatctacg gtgaaagtcg ttttgtagat
    62941 attactgact tgaatgaatt tcccaagcaa atgattcaac tgattgcccg ctatctatga
    63001 taaaataaag ctcaacgaac gcacttagca gattcgttga gcttttcgtt tctagttacc
    63061 ggtaacaagg atacttctaa aatagaatcg gttataatca agagggaccg ttaaaggagt
    63121 gaaacgatat gatacaagaa caaaaatggt ggaaagaagc agtaggctat caaatctatc
    63181 ctgctagttt caaagatagc aatggcgatg gtcaaggaga catcaatggg atccgtgaaa
    63241 aacttaatta tttgaaagat cttggtatcg gctttatctg gatcaatccg atctatcaat
    63301 ctccatttgt cgataatggt tatgacgtaa gtgactatca agatatagaa gagagattcg
    63361 gaacgatgga agattttgat ttattgctaa aagaagcaca tgaattaggg atcaaagtga
    63421 ttatggatct tgtcatcaac catagttcgg atcagcatca atggtttgaa gaatcgaaaa
    63481 aatctaaaga aagcccgtat cgcgattatt acatttgggt cgacggggta gatggcaaag
    63541 aaccgaataa ttggacatcg attttcggcg gttctgcttg ggagtattct catgaaactg
    63601 gacagtatta tctgcatgtt tttgcaaaag aacaaccaga cttaaattgg gaaagcgaga
    63661 aattgaaaga agaactattc aatatgatcc gatggtggtt ggataaaggg atagatggat
    63721 ttcgtttaga tgcgatttct catgtaaaaa aagatgaata ttcagtaaaa gccacagaga
    63781 accctttctc accctttcaa aatgtctcag gaatcgaaga acatttgacc gatttgaaac
    63841 atgtttttga agagtacgat atcatgactg tcggagaagc aagtggtgtc actgcagaag
    63901 aaggaccaca atgggtaggg aaagacggtt atttcgatat gatattcgaa tttgatcata
    63961 tccatatctg gcagcaagaa aaagaagggc aattagatgt ccttaaattg aaacttgcat
    64021 taagcgcttg gcaaacttca ttggatggta tcggatggaa cgctttatat atggaaaacc
    64081 atgatgttcc tcgtgccgtt tcagtgtttg gagatactcg tcccgatttt tgggctatgt
    64141 ctgcaaaagc aatcgctatg atgtatttct ttttgcaagg tacgccattt atttatcaag
    64201 gacaggaaat cggaatgacg aatatgccct ttgaatcgat cgatcaagtt gatgcagtag
    64261 attcgaaaag actttataaa aggctgcttg cggaaggtaa gacaagagaa gaagcattgg
    64321 atatcattcg tgaaacaacg agagacaaca gcaggacacc catgcaatgg acttcggaac
    64381 aatatgctgg tttttctaca catgaacctt ggctgatcac taatccaaat accaaaacga
    64441 tcaatgtaga acaacaagaa tatgaaccag agtcggtcct gcaattctat aagaacatga
    64501 tccgcattag acaaaccaat aaaggtctga tatacggttc ttataaagaa tatcttcatg
    64561 aacatccaca actttatgtc tatgaaagat atttagaaga tgaacaatat cttattatgg
    64621 taaacttaac agaatcactt gctgactatg aacttccaaa agaagcagat cagtcctgga
    64681 cattactctt gtcaaattcc tctagcggag aatttgaagc taaaggcata ctagcacctt
    64741 atgaagctcg gttatataaa acaaacaagt aaaacttcct cgttaaagtt cattagttgg
    64801 actttgcgag gaagtttttc agattgctct gtcaattact catttcaata attcgctcta
    64861 ggaccaccga tatatttagg acgagagcga agggctgtca cgtgagcttg tccaagggtt
    64921 ttcaaacgag gtctgacagg tacttggaca tgtttgatat gcataccgat tgatgtgtca
    64981 ccgatatcga taccggcttg tccaactacg tgttccactt cgacaggatc attgaactgg
    65041 tcaaaagcag caacagaaca agcacctcca gcatgtagtg caggaacaac agagacaatt
    65101 tcgaaatttt ttgcttctgc cactgttcgt tctactacta atgctcggtt caaatgttca
    65161 caaccttgga cagctagcgc aatttcttta ggatccaaca actcttttaa cgtacggatg
    65221 atccattgac caacttccgc actggaattt tttccaatat gtcctccaac gacttcgctt
    65281 gtgctgcatc ctaaaacaaa aagatcacct tttttcaagt gtgcctcagc caatatgtca
    65341 ttaactattt cagtcaattg gtcttttaat tctttttctg acaacttcat tttctaaaac
    65401 cttctttttc aattaatatt gcttccgtgc ttgaatacgt tgaagacttg cagttatagg
    65461 aaaggcaagt cccattccaa tcagattttg gaagatgttt cctggtatag aagccactcc
    65521 agccggccaa tcatataaaa tccaaccggc gataccatag ccgatgatca taactaagct
    65581 tcctaataaa agccctaatc cccacatacg agtagaagat ttgctgaaag aaccagcaac
    65641 atatccttgt aacccgtgga tcactaatga aaaaactgcc cactgcggat atcctgaaat
    65701 caaatcgatc aatagaccac tggaagcacc aacaactaat ccacccgttg gaccataaag
    65761 aaaagcagcg gtatagatcc cggcctcgca taatgtcaca aatccattcg tagccggtac
    65821 agggatcaaa attgttaatg aaagggcaac tgtcaacgca atcagcatag catagatcgt
    65881 taattgctta gttttcattt ctcattcctc ctttttgaat accgccagac cagacacttc
    65941 cggtatgatc gttcatcagc acgccattag aaatacaatg ggcaacaaat tttttacttt
    66001 ctgctactgc tttggtaaaa tctgccccta acacaagatt cgctgttatt gcagaagaaa
    66061 aggcacaacc ggccccgttt actgttgtag tgtcgatttt tttatgagaa aatacctcat
    66121 aatgatcaat tgaatagaga agatccacag cttcatctcc agccatcctt gtgccgcctt
    66181 tgatcacaat gttttttgtt cctgaagcag tgagttcttt agcgagatgg atcatttctg
    66241 ttaacgaaga gggaagagct tgaccagaaa gtaaagcagc ttctgccaaa ttaggcgtaa
    66301 tcatcgtaac aagtggaaaa agttcttcga tgagctgcga aatatacaat tgattgatca
    66361 cagcttcagt ttctttgaat gccaaaacag ggtctaaaat gattgggata ttttgttttg
    66421 tttttatgaa gtctcgaaca accatgattg cttcacttga attcaataac ccaattttga
    66481 taccatctaa tgaagtcatt ttatcaatcg aaactaactg tcgtttaagc aattccaaag
    66541 atatagattc cagcataaat cgctcattaa tatctagtgc ccctatagaa gtcaaggcgc
    66601 ttagtccgaa tagaccaaaa ttctcaaaag tttttaaatc tgtttggatt cctccaccag
    66661 caaatggatc agaaccgcca attgtcaaga ttcttttcat aacattttcc tccatgaata
    66721 agagtataac gaaattttca aaaaagaaaa acagccaatt ggcatatttt tatctcatcc
    66781 aatttaaaaa aacaaaaaga aaagaaagac caaaatggat ctttctttcc ttaaatagtt
    66841 aggacttttg tgattttaat tctttctcga tttgaagccg ttgcactttc attgtagctg
    66901 ttcgcgggat tgcatcaaaa tcacggatga tagggacgtt caagcgagga agttcatgga
    66961 cttgctccca ccatcgattc caatccattt ctttatcagg agctaaagca ataatcggtt
    67021 gtggagaatg atttttatcc cttacaatca ctacttctgc caaaaaatct aacgaatcta
    67081 ataaaaagtc ttcaatagct aatgtactat tgatcgtttc gatcaaatcc acttgccgat
    67141 ctttcaaaaa taggtggcca tgcttatcca taaaaccgta atctccgcta tcccaccaat
    67201 cgccataaac attttcctgg aaccgtgcat cttccttgta ataagtcaaa gcccgtcctt
    67261 tagacagtaa ttgtatatga ccatctgtgt tttcaggtag gacattccca actgaatctg
    67321 taatccgagc gcttgtcatg tcttccagtc caacgcccat atctcttgca tcacttgttt
    67381 tcaaactctc tagtgtatga gccttaagaa tcattggtcc gcattcactt tggccatata
    67441 cttgaagaaa taccgcatcc tgtgccatcg acgttcgcaa aaatgtcttc attgtctggt
    67501 tgtttatagc atcaaaagtg gagtgatagt atcggatacc cgaaaaagct tctggatgct
    67561 ccttagcagt aaaacgccac tgaacaaagt tattcggatg ggtctctagt gcaattggcc
    67621 ggtgagcttc caacatatga acaacttttg aactttgtgc gtttgctaaa ggcatcatag
    67681 gaaatcccat ggacatcaaa gaagagatac caatattgaa tctggaatgc actggagaga
    67741 tgtgaaaagc gattaatttc ttttccgaaa tttttgtgaa aactgttttt tgccatttcg
    67801 tccgccatcc catagaatga gcagaatgac aaataagttt agggatacca gttgtaccag
    67861 aagtatgggt catataagaa atttcatttt tgtctaaaaa tgattgagaa acagacaaag
    67921 caggttgttc cattaaataa agaatagg
//
LOCUS       DAZKPE010000009        66146 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000009 DAZKPE010000000
VERSION     DAZKPE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.009"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(139..438)
                     /locus_tag="ACG930_000651"
     CDS             complement(139..438)
                     /locus_tag="ACG930_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0517834.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            789..1421
                     /locus_tag="ACG930_000652"
     CDS             789..1421
                     /locus_tag="ACG930_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFQ0517835.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            1544..2182
                     /locus_tag="ACG930_000653"
     CDS             1544..2182
                     /locus_tag="ACG930_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFQ0517836.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(2301..2373)
                     /locus_tag="ACG930_000654"
     tRNA            complement(2301..2373)
                     /locus_tag="ACG930_000654"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2338..2340),aa:Thr,seq:cgt)
     gene            2494..2736
                     /locus_tag="ACG930_000655"
     CDS             2494..2736
                     /locus_tag="ACG930_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517837.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(2875..3504)
                     /gene="upp"
                     /locus_tag="ACG930_000656"
     CDS             complement(2875..3504)
                     /gene="upp"
                     /locus_tag="ACG930_000656"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFQ0517838.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3638..4585)
                     /locus_tag="ACG930_000657"
     CDS             complement(3638..4585)
                     /locus_tag="ACG930_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFQ0517839.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(4738..5982)
                     /gene="glyA"
                     /locus_tag="ACG930_000658"
     CDS             complement(4738..5982)
                     /gene="glyA"
                     /locus_tag="ACG930_000658"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFQ0517840.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(6173..7198)
                     /locus_tag="ACG930_000659"
     CDS             complement(6173..7198)
                     /locus_tag="ACG930_000659"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFQ0517841.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(7220..7399)
                     /locus_tag="ACG930_000660"
     CDS             complement(7220..7399)
                     /locus_tag="ACG930_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517842.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(7392..8231)
                     /gene="prmC"
                     /locus_tag="ACG930_000661"
     CDS             complement(7392..8231)
                     /gene="prmC"
                     /locus_tag="ACG930_000661"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFQ0517843.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(8224..9297)
                     /gene="prfA"
                     /locus_tag="ACG930_000662"
     CDS             complement(8224..9297)
                     /gene="prfA"
                     /locus_tag="ACG930_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFQ0517844.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(9300..9884)
                     /locus_tag="ACG930_000663"
     CDS             complement(9300..9884)
                     /locus_tag="ACG930_000663"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFQ0517845.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(9990..10238)
                     /locus_tag="ACG930_000664"
     CDS             complement(9990..10238)
                     /locus_tag="ACG930_000664"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0517846.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            complement(10229..10459)
                     /locus_tag="ACG930_000665"
     CDS             complement(10229..10459)
                     /locus_tag="ACG930_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517847.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            10565..11167
                     /locus_tag="ACG930_000666"
     CDS             10565..11167
                     /locus_tag="ACG930_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFQ0517848.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(11271..11840)
                     /gene="lepB"
                     /locus_tag="ACG930_000667"
     CDS             complement(11271..11840)
                     /gene="lepB"
                     /locus_tag="ACG930_000667"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0517849.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(12070..12837)
                     /locus_tag="ACG930_000668"
     CDS             complement(12070..12837)
                     /locus_tag="ACG930_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFQ0517850.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            complement(12834..13313)
                     /locus_tag="ACG930_000669"
     CDS             complement(12834..13313)
                     /locus_tag="ACG930_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFQ0517851.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(13438..14175)
                     /locus_tag="ACG930_000670"
     CDS             complement(13438..14175)
                     /locus_tag="ACG930_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFQ0517852.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            14336..15736
                     /locus_tag="ACG930_000671"
     CDS             14336..15736
                     /locus_tag="ACG930_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFQ0517853.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            15959..17311
                     /locus_tag="ACG930_000672"
     CDS             15959..17311
                     /locus_tag="ACG930_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFQ0517854.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            17304..18002
                     /locus_tag="ACG930_000673"
     CDS             17304..18002
                     /locus_tag="ACG930_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFQ0517855.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(18064..19215)
                     /locus_tag="ACG930_000674"
     CDS             complement(18064..19215)
                     /locus_tag="ACG930_000674"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFQ0517856.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19228..19665)
                     /locus_tag="ACG930_000675"
     CDS             complement(19228..19665)
                     /locus_tag="ACG930_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0517857.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(19680..21446)
                     /locus_tag="ACG930_000676"
     CDS             complement(19680..21446)
                     /locus_tag="ACG930_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFQ0517858.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            21710..22387
                     /locus_tag="ACG930_000677"
     CDS             21710..22387
                     /locus_tag="ACG930_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0517859.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            22390..23517
                     /locus_tag="ACG930_000678"
     CDS             22390..23517
                     /locus_tag="ACG930_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517860.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(23717..24157)
                     /locus_tag="ACG930_000679"
     CDS             complement(23717..24157)
                     /locus_tag="ACG930_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0517861.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(24168..26201)
                     /locus_tag="ACG930_000680"
     CDS             complement(24168..26201)
                     /locus_tag="ACG930_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFQ0517862.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(26203..27906)
                     /locus_tag="ACG930_000681"
     CDS             complement(26203..27906)
                     /locus_tag="ACG930_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0517863.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(28000..28950)
                     /gene="manA"
                     /locus_tag="ACG930_000682"
     CDS             complement(28000..28950)
                     /gene="manA"
                     /locus_tag="ACG930_000682"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFQ0517864.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(28989..30014)
                     /locus_tag="ACG930_000683"
     CDS             complement(28989..30014)
                     /locus_tag="ACG930_000683"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0517865.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(30223..31092)
                     /locus_tag="ACG930_000684"
     CDS             complement(30223..31092)
                     /locus_tag="ACG930_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0517866.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(31796..33688)
                     /locus_tag="ACG930_000685"
     CDS             complement(31796..33688)
                     /locus_tag="ACG930_000685"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517867.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(33685..35412)
                     /locus_tag="ACG930_000686"
     CDS             complement(33685..35412)
                     /locus_tag="ACG930_000686"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517868.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(35428..36078)
                     /locus_tag="ACG930_000687"
     CDS             complement(35428..36078)
                     /locus_tag="ACG930_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFQ0517869.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            36282..36578
                     /locus_tag="ACG930_000688"
     CDS             36282..36578
                     /locus_tag="ACG930_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0517870.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            36770..37390
                     /locus_tag="ACG930_000689"
     CDS             36770..37390
                     /locus_tag="ACG930_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFQ0517871.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(37482..38648)
                     /locus_tag="ACG930_000690"
     CDS             complement(37482..38648)
                     /locus_tag="ACG930_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0517872.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(38660..39013)
                     /locus_tag="ACG930_000691"
     CDS             complement(38660..39013)
                     /locus_tag="ACG930_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFQ0517873.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            39141..40163
                     /locus_tag="ACG930_000692"
     CDS             39141..40163
                     /locus_tag="ACG930_000692"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFQ0517874.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            40182..40343
                     /locus_tag="ACG930_000693"
     CDS             40182..40343
                     /locus_tag="ACG930_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517875.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(40602..41036)
                     /locus_tag="ACG930_000694"
     CDS             complement(40602..41036)
                     /locus_tag="ACG930_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517876.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(41146..43005)
                     /locus_tag="ACG930_000695"
     CDS             complement(41146..43005)
                     /locus_tag="ACG930_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0517877.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            43006..43146
                     /locus_tag="ACG930_000696"
     CDS             43006..43146
                     /locus_tag="ACG930_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFQ0517878.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(43123..44283)
                     /locus_tag="ACG930_000697"
     CDS             complement(43123..44283)
                     /locus_tag="ACG930_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0517879.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(44590..46014)
                     /gene="araA"
                     /locus_tag="ACG930_000698"
     CDS             complement(44590..46014)
                     /gene="araA"
                     /locus_tag="ACG930_000698"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFQ0517880.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(46030..46728)
                     /locus_tag="ACG930_000699"
     CDS             complement(46030..46728)
                     /locus_tag="ACG930_000699"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFQ0517881.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(46685..48346)
                     /locus_tag="ACG930_000700"
     CDS             complement(46685..48346)
                     /locus_tag="ACG930_000700"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFQ0517882.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            48564..49964
                     /locus_tag="ACG930_000701"
     CDS             48564..49964
                     /locus_tag="ACG930_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFQ0517883.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(50216..51295)
                     /locus_tag="ACG930_000702"
     CDS             complement(50216..51295)
                     /locus_tag="ACG930_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0517884.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(51381..52340)
                     /locus_tag="ACG930_000703"
     CDS             complement(51381..52340)
                     /locus_tag="ACG930_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFQ0517885.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(52352..53863)
                     /locus_tag="ACG930_000704"
     CDS             complement(52352..53863)
                     /locus_tag="ACG930_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0517886.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(53885..54449)
                     /locus_tag="ACG930_000705"
                     /pseudo
     CDS             complement(53885..54449)
                     /locus_tag="ACG930_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            complement(54455..55318)
                     /locus_tag="ACG930_000706"
     CDS             complement(54455..55318)
                     /locus_tag="ACG930_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517887.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(55332..56228)
                     /locus_tag="ACG930_000707"
     CDS             complement(55332..56228)
                     /locus_tag="ACG930_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517888.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(56403..57692)
                     /locus_tag="ACG930_000708"
     CDS             complement(56403..57692)
                     /locus_tag="ACG930_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0517889.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(57664..59181)
                     /locus_tag="ACG930_000709"
     CDS             complement(57664..59181)
                     /locus_tag="ACG930_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFQ0517890.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            59379..60269
                     /locus_tag="ACG930_000710"
     CDS             59379..60269
                     /locus_tag="ACG930_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFQ0517891.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(60342..61166)
                     /gene="nadE"
                     /locus_tag="ACG930_000711"
     CDS             complement(60342..61166)
                     /gene="nadE"
                     /locus_tag="ACG930_000711"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFQ0517892.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(61178..62650)
                     /locus_tag="ACG930_000712"
     CDS             complement(61178..62650)
                     /locus_tag="ACG930_000712"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFQ0517893.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(63287..63649)
                     /locus_tag="ACG930_000713"
     CDS             complement(63287..63649)
                     /locus_tag="ACG930_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFQ0517894.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            63872..64624
                     /locus_tag="ACG930_000714"
     CDS             63872..64624
                     /locus_tag="ACG930_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0517895.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(64764..65687)
                     /locus_tag="ACG930_000715"
     CDS             complement(64764..65687)
                     /locus_tag="ACG930_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0517896.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(65702..65974)
                     /locus_tag="ACG930_000716"
     CDS             complement(65702..65974)
                     /locus_tag="ACG930_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517897.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        19146 a        13544 c        11481 g        21975 t
ORIGIN      
        1 aggataaaat acaatataaa gaaacatctg tttctttatt tagaataaaa aaatacagac
       61 tctgttcaaa taaatgaacc tagcctgcat tatgagattg actatacttt ttaattcatt
      121 gagatgaata actcgttttt ataaatgccc aaaagtaatc ggtgccgaag ccattcctcg
      181 acctaattct ttttcaaatt ttcctattgt tgatatctcc atataaaacg gtgatactgg
      241 tttagacaat tctcccctga ttgctaacgg acgtaaacta cgttccaaat tatttatgac
      301 tttaggataa tactgacctt tttctaagcc tgtctttgcg tctatcaaaa gtatacgttc
      361 cttttctttg atctctggat ttaaaacgag atcatataat tttagtacca tgttttctat
      421 ttcttcactt ttagacatca cgatttcctc ccaaaaatat atttcttccc actacattct
      481 ataaacaaag tatacgctac atctagattt ttttaaatca ttactggatt gttaaaacct
      541 ttcaatacac tgttatggca acgattttta ttttaaaaac attctaaatt aaatcagtaa
      601 aaatttttat tctaagattt ttattagaat tacgcctaat ttgtgtctct cagggcaatt
      661 ctaagaacgt ttcaagagat agcgacacta tcgttatcga aaaaggcgaa aacctatctc
      721 attttctgct aatgtaagtt ggtttagctt ttgttaatat gactttatga aaatggaggt
      781 aattaaatat gatttttcct aaagttaatg aagcaagctt gaataaagga tccttttttc
      841 atatctatga aaacgaagat tttgaactgt ataatatcct ttcacaaaaa gaggtcatcg
      901 aaaaccaaat aatctgccat ccaattattt acaaatctat tttcaagtat gcattttttg
      961 cttccaatga ttttcaaaga atggagatta ccgactgtat attcgaaaac tgtgattttt
     1021 caggctgtat attgacaaaa agcatgttgc atcgcgtgaa atttgtcaat tgtaaattaa
     1081 caggtactaa attgatggaa agttatattg ggaacacgtt attcgagaat tgtaaaatgg
     1141 actatgtaaa tttatctggt tcaaacataa aagaaagtac ctttgagcac tctgtcttat
     1201 caagcgcaga ttttgtagac tgttccctca ctaaaataat gttttctact aatgatttag
     1261 aaaatgctag cttttttgat actgatttaa aaaatatcga tttaagtagc aactcctttg
     1321 aaatgattga agtacgctcg gaacatctaa aaaattgtac gcttaatcag ttgcaagcac
     1381 ttggttttgc tagaaaattt ttacaaataa aagtagtata atcaaaatga atatataaga
     1441 taaattttta gcaatacaaa tatccataaa aaaacattgc ctattttaac tcttcatgta
     1501 tactgactct atcttcaaaa actgaatagt aggagttatt atcatgaata acattttagg
     1561 aaaaaaaata gaacttaaaa aagggatatt gggcactatt gtcgttgtac tcggtttgtt
     1621 agggttgcta tttgcgccat ccattattag cattttttct ttaactatca ctggatttat
     1681 agcatttaca cttgtttttg gtaaaaaaga tacgaaaaaa atgttctcga aacctgtcgc
     1741 tcctgtcaaa aatatagcca aatatttttt tatcaatgta gtaatcagtg ccgcagtctc
     1801 ggtatttttg caacaaattt tgaaatgggg tttaacaggc aatccaataa atgaggcttt
     1861 cagcccgtta ttatttatta ttttgcctat catgatactt ggagaagaat tgttctcagt
     1921 gtattttctc gctatttttt ctagtaagtt cagcattcct gtcgctagtt tcttgtcagc
     1981 aatcatcttt ggatttatcc attacagtac ttatgataat ggaaatattt tacacactgt
     2041 agcacacatc cttttgatac aaggggtggc aagattgtta ttcaaccaag ctgccattaa
     2101 aagcaactcg atcattacaa gttgggcagt tcatgtgata tttgatttca cagctatatt
     2161 gctagtcgtt ttattctcct aaatttttat agaaataata catgctctat tgctaagaaa
     2221 gcatacttta tttcctttaa acaaaaagac agatgtatca atggattaaa aatccttgat
     2281 atatctgtct tctcttttaa tgccagctat agggatcgaa cctacgacct acgcgttacg
     2341 agtgcgttgc tctaccaact gagctaagct ggccttatcc aaaagaaatt atatactcta
     2401 tttggctgat tgtaaagagt ccgatggaaa attagtttaa tttcatgata tttttcataa
     2461 aacgtggtat aattgatgtg aaaggcaggt tttatgaaaa tggcaacttt tggaaaattt
     2521 gatacaacta tcgtaccatc ggaaattggt gaaaaattca agatcaatac tcacgtaatg
     2581 ttcacaattc acggcaagtc gcaaactgga acgatttcaa agcaattgaa aaattccgct
     2641 gttgttgaga ttgatgaaac tgcagaaaat gcgaacttga tgacgcaaag taagggtgta
     2701 gtaatcgtta actacaaaga actaaaaaag atttgaattt gaccatctct gcatttttgg
     2761 gatggttttt ttatatgcaa acgaaagctg tgaaaaagct gttctgcatc aaacgttaaa
     2821 aatgaccaaa aaaggatgtg acaaaagttg tgtcacaccc tttttcgtat ttacttattt
     2881 tgtaccaaac aaacggtcac ccgcatcccc tagtccagga acgatataac catgttcatt
     2941 caatttttca tctagagaag ctgtatagat gtcaatatca ggatgcgctt cttgcaaagc
     3001 ttttactccc tcaggtgctg ctaccaaaca aacaaattta atgttcgacg cgccacgttc
     3061 tttcaatgca tcgattgcca tgattgctga tccgcctgtt gccaacattg gatctactac
     3121 aaacaactga cgtgcatcaa tgtcttctgg aagtttgacg aaatattcat gtggttccaa
     3181 tgtttcttca tctcgataaa gaccgatatg tcccacttta gcagctggaa tcaattccaa
     3241 gataccgtca accattccaa tacctgcgcg caagattgga ataatcgcta cttttttacc
     3301 agacaacgtt ttttgtgttg tttcagtgat cggtgtttcg atcacgatgt cttccaatgg
     3361 catatcccgt gatacttcat atgccatcaa catagcgatt tcatcgacta cttcacgaaa
     3421 aacctttgtt ccgcagtttt tgtcccgaat aatagttagt ttgtgttgaa tcaatggatg
     3481 atcgatcact tgaaatttgc ccatttttta agctctcctt tgttctgtcg tttcttttta
     3541 attgtaaaac aaaatcaagt gattgactag tcaaactcgc catttttcct aagaaaatcc
     3601 gtttttgaaa agaagttttc ctgcggacaa gcaaagctta ttcttttttc ttgatccaag
     3661 aagtagataa tgccattgct gcacgcgttg cctttgtctg atccatagca tttaccatga
     3721 caaaatcatg gatgattcct tggaagcgta cttgtgtaac aggaacccct gcatcacgaa
     3781 gtttgcgcgc ataagcctca ccttcatctc ttaatacatc cgcttctccc gttaaaatca
     3841 ttgctgaagg aagatcattt agttcattta tatttgctct caaaggcgaa gctgtgattt
     3901 cagcacgctc ttcttcattc gtcgtatatt ggtcccaaaa ccacatcatt ccttctcttg
     3961 tcaaaaaata gttttctccg aattcatgat aggaatctgt atcaaaatca gcgtttgtga
     4021 ctggataata cagcaattgc ttggatattg ggaggccctt tcgttctttt gttaagatcg
     4081 tcatgactgt agccatgtta ccacctactg aatctcctgc aacgattaga ttctcgagat
     4141 ccagattttt tgacttggct aatttattca gctgttgcaa cacagcataa ttttgttcaa
     4201 ttgctgttgg atattttgct tctggtgatc gactatattc tggaaagaca acgacggaat
     4261 tcgtacgaac cgcaagttct ctgatcaatt tatcatgggt ttgagcactg ccaaaaaccc
     4321 agcctgctcc atgaatataa aaaataactg gtaatttatc catattccct tctggtcgta
     4381 cgagacgaat attgagtttt ccccattcgc cagtatccac catcaagtct tcaatatcga
     4441 cggaatattt gttcacaggt gattcttgta cttcttctag taaaactctt ccttcttccg
     4501 gtgctagttc atagatacgc ggatgaggcg catttgcatc actgaatgct actgcttcct
     4561 tttctaacga gatacgatca gtcatgactt ttcctccctg agatttagtg tgaagactaa
     4621 aattacacct catatactag agagcatcac cgatattgtc aaagaatccg ttttcccaaa
     4681 aaataaacag aaaagcccaa cattgaactt ttctgtttac taatggaatt taaattttta
     4741 ttttttatgc aacggaaatt tttcagttaa ttcgcgtaca cctgttttga cttcgtctag
     4801 ttgagcgtta tcatcttttg cttgtaatgc tttgacaact agttcagcca cttttacagc
     4861 atcttcttct ttgaacccgc gagtagtgat tgctggcgtg ccgattcgaa taccgcttgt
     4921 tttgaatgga cttagtgttt caaaaggaat cgagttttta tttacagtga tattcacact
     4981 gtccaaaatg ctctctgctt cttttccatt tatacctaac tcgcgaacat cgatcaacat
     5041 cagatgatta tctgtcgccc ctgaaatgac tctggttcca attgcttgat tgaaaacttt
     5101 gaccattgct tttgcattgg cgatgatttg ttcactatat tctttaaatg caggatctaa
     5161 tgcttctttg aatgctactg ctttacccgc aatcacatgc tctagagggc cgccttgaat
     5221 accaggaaat accgcactat ttattttttt tgctaatgct tcatcgtttg tcaaaatcat
     5281 gccgcctcga gggccacgca atgttttatg agtggtagtc gttgtgatat ctgcataagg
     5341 aactggatta ggatgaagtc ctgctgctac taatcctgcg atatgtgcca tatctaccat
     5401 cagttttgcg cctacttcat ctgcgatttc tctgaatttc gcaaagtcga tcgttcgtcc
     5461 gtaagcactg gcacctgcta cgatcaattt tggttgatgt tttctagcta aaatacgtac
     5521 cacattataa tcaataactt ctgttgtcgg atcaacaccg taagcaacaa agtgataggt
     5581 tttgccactg aagttgactg gtgatccatg tgttagatgt ccgcctgcgg aaagatccat
     5641 tcctaagatc gtgtcccctg gttctaccaa agcgagataa gcagccgtgt tggcttgaga
     5701 gccggagtga ggctggacgt tcgcaaattt cgctccgaat aattcttttg cacggtcaat
     5761 cgctaaattt tcaacgatat cgacaaattc acacccacca taatagcgat gccctggata
     5821 accttctgcg tatttatttg tcaagatact tccttgtgca gccatcactg cttcggagac
     5881 aaagttttca gaggcaatca gctccaaatt atgttcttgt ctttcttctt ctttggcgat
     5941 cgcagcccaa agatcagggt caaacgtttt gtaatctacc acaaacaaca gctccttttt
     6001 attttcctac aattttattt tcctacaatt ttatttttcc catcaaaaac aaattgccaa
     6061 atattcgtat ctcttctatt acgattagtt acgcttagtt tttcgttcac tgatagaaga
     6121 tttacttgat agcattgtat catactaaaa gaatgcgaca ataaccaatt gatcattttt
     6181 caaaataatt ttgtcctgct gcttttttca agcgattcat gtaagcattc cccaatccag
     6241 tttctggata cacttgtaca aaaatcaaat ctaatccaag tgttggttca tctaatcctc
     6301 ttagacctgc aaacaatcct ttagccgccg cttctactga gttgtcgtta tacatataaa
     6361 cagctgcagt atctgtccgc acttgatccg caatttcggg gcttgctatg acacctgcac
     6421 ggatcttctt attttttgcc cattgaactg cagttgacca atcgccatct ctgaccatca
     6481 gaacacgtgt atcgggtgag tagtgtttgt atttcatccc aggggctttt ggtgtttcat
     6541 tttcttttac aagatgctga tcaatagcaa caggagattc gatgactgct tcgatttgtt
     6601 ctttcgttac tgcacctggt cgtaaaatca taggcatggc tgttggatca cttaaatcaa
     6661 gaacagtgga ttctacacca attcgcgtag ctccatcatc aataatcccg gtaatttttc
     6721 cttgtagatc atgatataca tgatctgcag tcgttggact tggttttccc gacgtatttg
     6781 cacttggacc gacaagcgga acaccggaaa gttcgattac ttctagtgtt tttttgttat
     6841 ccggtatacg aaatgcagct gtggataatc ctcccgtcac aactgagggc aaagtgtctt
     6901 ttttgatctt aaatatcaaa gttaatggtc caggccagaa gttcttcaca atcttctctg
     6961 ctgccggatg aaagttgtcc acatactctt ttacttgttc aaaagaggcg acatggacga
     7021 ttaatggatt atcttgcggt ctccctttta cagaaaacac tttcttgaca gcgtttggta
     7081 aaagagcgtt ggcgcccaat ccgtatactg tttcggtagg aaaagcaaca agttctcctt
     7141 ctttcagtgc ttcggctgcc tcttgcaatt ctgtttcatc atatcgtttc gtttccacag
     7201 tttatccaca accccttttt catacattct tattttgtct gagtttatcc tcaagttttc
     7261 cactgtttgt ggataatcta tttgtcaata gtggataaac ttgttgataa accaaaaagt
     7321 cgtttacatc cttgtcaaat aagtgttttt ttataataaa aaaacaaata aaaaattttt
     7381 catccacaac ttcaaccata aacttggatc attcgttcat tgccaaaaag atcctttttt
     7441 atcgccactt ttttatctgg aaatgcttgc tgaaatattt tttttactgc ttcaccttgg
     7501 cgaaatccga tttctaaaaa aatctttcca tttgatttta gtacgcttgg tgcttcaact
     7561 gctatttttt cataaatagc taatccatcg ttctcagcaa aaagggccat tttaggttcg
     7621 aatgaccgga cactttcatc catcagttcc cattcattcc gactgatgta cggcggatta
     7681 gaaataatca catcaaattg ctgatccatt actggtccta atgtatctcc atgataaaaa
     7741 ctgattttcg ttccttcttt ctgagcattt tctttcgcta cttctaatgc ttcttctgaa
     7801 agatccacag cagatatatg ccaatttttt cttgctgctt tcaaactaat agcaattgct
     7861 ccagtccctg tcccaatatc tatcacttct aacggtacac caggcgtctc gtctaaacac
     7921 cattcgacta actcctctgt ttctggtcga gggatcagtg ttgcttcagt tacctttaac
     7981 cgatgatcat aaaaatctgc atatcctagc aaatactgag gtggatgatc tgcaagcaga
     8041 agtcgcagat cggtttcgat caaccgctgt tcttcttctg aaatctcttc gttcatatga
     8101 aggagccaat caagtttttt ccattgtttt cgttccaaaa ataaaaattg gatactatat
     8161 gcttctttcc catgatcctc taaaaaagaa gaagcccgtg acaggacttc tcgataggtc
     8221 attttaccca ttttgcatag cttccagttt tgatgtttga tcatacatga tcaatgcatc
     8281 aacgatctca tctaatttcc ctgctaaaat ctgatctaat ttttggatag ttaatccgat
     8341 acgatgatca gtcacacgat tttgcgggaa attatacgtc cggatccgtt ctgaacgatc
     8401 cccagttccg actgctgatt ttcgattggc atcatactcg ctttgtgctt cttgctggat
     8461 cttatcgtac acacgagcac gcaagatttt cattgctttt tcacggttct tgatttgaga
     8521 acgttcatct tgcatagcaa caacgatccc tgttggtaag tgagtcaaac gtacagcaga
     8581 tgctgtttta ttgacgtgct gtccgccagc acctgaagca tgatagatat ctgtacggat
     8641 atctttgtct tcaatatcga tctctacttc ttcagcttct ggcatcacga caactgttgc
     8701 ggtggaagta tggatacgcc cttgcgattc agttgaagga acacgctgga cgcggtgcgc
     8761 accactttca tattttaatt tcgaatatac gttgtctccg gtgatcatca tgatcacttc
     8821 tttatatcca ccgattccgg taacgttagc ttccatcact tctgttttcc agccttgtgc
     8881 ttcagcatac ttttggtaca tattgaaaag atcgccagcg aataatgctg cttcgtctcc
     8941 gcctgctgct ccacggattt ccatgatgat atttttatcg tcatttggat cttttggtaa
     9001 aagcaagatc ttgatttttt cttctaagac ttctttttct ttttttaatt cagataattc
     9061 ttcttttgct agttcagcca tttcatcatc cagtttttca ccaagcagtt cttctgtatc
     9121 ggtgattcct tgtactactt ctttataacg acgataaact tcgactgttt cgcgcgtgtt
     9181 tgcttcttct tttgaaagct gcataaaacg ctttgtatca gaaatcactt ctgggtcact
     9241 taaaagttct ccaagctctt cataacggtc ttcaattgct tgtaattgat cgtacatgct
     9301 tattctcctt ctgtaatcat tgatgggtga aagtaatgtt ttcgacaaac ggggtaataa
     9361 gcttcatttc cgccaatttg cacttgatcg ccttcataaa cagggtttcc atcaatataa
     9421 tgtaaattca tgattgcttt tttgtggcag aaccaacaga ttgttttcat ttcttcgatt
     9481 ttgtctgcat aaagcaataa atattttgat ccttcaaata actcgtttcg aaaatcattt
     9541 ttcaaaccaa atgccataac cggaatatcc aattcgtcca caattctcgt aaaagcaatg
     9601 acatgtttct tttttaagaa ttgcgcttca tcgatcagca cacaataggg tttgctttcc
     9661 attttctgaa ttacgtcaaa tacgtctgtt tcttcaaata tcggcatcgc attacgtttc
     9721 agtccgattc ggcttgaaac aacgcctaaa ccatctcttg tatcaatacc gcttgtcatt
     9781 aagacaactg gcttattttg ttcttcataa ttatgtgcga cttttaggat ctcgatcgtc
     9841 ttgccgctat tcattgcgcc atacttaaaa aatagttgtg ccatgctctt tttcaccttc
     9901 cagtttgttc ctatggtatt atacttgatt ttcagcattt tttacagtga gaattttcat
     9961 caagcacaga ttagtattaa atctattgct cacttttgtt ccaatttttt gacaagaact
    10021 aaacatgggt tccattcatc ccataaattt ggaaaaactt ccaaccttga aaatcctaat
    10081 gattcgtaga aacaaatagt ttgatcatat atagagtagt gcccctcgtc tacagtcttc
    10141 acttgcaaat atttgtaatg ttttgctgcg taaccttctg cttctttaaa aagttttgtt
    10201 cctaatcctt ggtgatgata gtcttttttt attcccatac aatagaatag atttcggcag
    10261 tatcttcact tgtctgtgaa agagtgataa agcctaaata ttcttctttt cttttttcac
    10321 accataaagg tagtttactt gattcctcga tatatttttc cgttgattca ggaagcccaa
    10381 accactcagg caagtctagt aatatttctc ggacacactt tcctttttcc tctctatctt
    10441 ttacaaacga tatcggcata ttctttctag attctccctt tttgaattga gtatagcatg
    10501 ctttctttct tttcacgtgc tataataagt taaaatttca aagttttacg taaggagcta
    10561 tttgatgaca aaaaatattt ttgattccat cgctaaccat tatgattccc ctgaccgtca
    10621 agcattagcc aagattattc gcgaagaact aactacttat ctaccgcgcg acagccacca
    10681 aaaagtcctg ctggattacg gaggcggaac tgggcttgtt agtttaccgc ttgcggaaag
    10741 attcaaagaa ctgatcattg ccgatgcttc agaaactatg ctgaaaatgg cagaagaaaa
    10801 gatccaagca gcagatctga aaaatgtccg aacgatccac gctgatgctt ctgtcgaatt
    10861 tcctgctgtc caagctaatc tcatccttct atcacttgta cttttacaca ttcctgatac
    10921 ggagaatatt cttacaaaac tttatgaaat tttagctcct ggcggtcaat tgatcatcgt
    10981 agactttgac aagaatgaac aaattagtca tccgaaagtc cataatggct ttagccaaga
    11041 agaattgaat aatcgattgg aaaaaacggg ctttgtctct gctactagtc ataccttcca
    11101 tcgtggggaa aagctattta tgaacaaaaa cgcttcgctt ttcttatcca tcagccaaaa
    11161 agcttaaaat gagattgcaa aaaaagtgag caactccaag aaataagaag gaattttcgg
    11221 aaaaagaagc tgtgacaaaa aacatgtcac agcttctttt tattttttca tcacatgatt
    11281 ttaatttctg aaagaggcca ataacggaaa acaacttttc cttggatcat atctttgtcg
    11341 actaacccaa acattcggct gtcttttgaa atcaagcggt tatcgcctag aacaagatac
    11401 tttccttttg gcacagtata ttcaaagtca ctcgtaaagg tggatgaact ttctgcttgt
    11461 gcttggaatc ctgagctata agcatattct ccttgtaact tatcttctga aaattctttt
    11521 ttgaactcat ccagataagg ttcatcatac tttttgccat taatggtcaa ctggtcattt
    11581 tccatcttga ctgtatctcc aggcataccg atgatccgtt taacaatcat ccgttcttca
    11641 tcccccggtt cctttgtagt aataatatcc attcgttcat agtttgagat cttagatgaa
    11701 atcaatcgtt gtccatcact taatgtaggg tccatcgaat gcccgtttac agtaactggt
    11761 gtaaacacgt acactctagc taataaaata gccgctaata caaggatcaa aatcccccaa
    11821 tttttcaaaa attctttcac agcttacctc ctacttgtat tttcctcgtt atttattacg
    11881 ttttttcaca atacttcgtt gtactttctt tattctacaa tgtttataaa tgaaaggaaa
    11941 gaataagtga tgtgttcgtc ttatctttct cgttatataa aaaaggaacg tgacaaaaga
    12001 cgtgtcacat cccccttatt ccgaataaac gtttttatcg caaccactga tacacggcgt
    12061 ttcatcacat tatgaatgtc ttcttctttg gctacgacta taaaccactg gttcttcctg
    12121 cgactgtgcc ttttttgcaa tcaatttcag acgataaggc tcatgatagc gtaacccgtc
    12181 tttgacaaaa tcaccgccga cgatgaacaa tccgacaggt tccaatgtgt cttctgttga
    12241 gtcaagtcga atggtcccta ctttttccat gtccgagtag cttcgtccaa tatttagaac
    12301 atactctttc tctcctgttt tcttgacata gtaataagga tacaatgtat ttctatcgac
    12361 cagaaatcca tccatgcgac cgagttcatt tgttttgatc tcaccatttc caatcaaata
    12421 ccgcatattc tcggctaatt tcaattgata atcttcgtca taagaaacca tgacctcttg
    12481 tgtattcact ttatcgatcg aatttccatt atctatcgat tcttctgtct ggatgttgaa
    12541 cgcttcatca ggtaaatact tcacaaaaag ctgagtgaca tcggctttcg tgtttttatc
    12601 taaaaagtaa taaaatacat ttaaaacagt aaaataaaca agcactagaa atgcaagtcc
    12661 atataagaaa aattgaagat agttttggtt ttgccaaagt ccataaacaa ttctcaataa
    12721 ataaagcgtg ggaatcacac ttaaaatcgt atatccacgg ttaagatatt taggactgat
    12781 gtctaaatag ccaaggaatt tatgcacccc gttgataagg tctagtaaaa atgtcattga
    12841 gaatcacctg cttgctggtt atacgtttgg gtatttcctg aatcttggtt ttgctgtgct
    12901 gtacgtgctg catcatcatt ttgcgtgtta tcatctacag tcgtactgct tggtatcgtt
    12961 tcggagctag cacttgtatc cggacttgta cttggattgg ttgaatccga tggagtgcca
    13021 tctggtaccg tattacttgt ttcgcttgag ctgtcagttg tatatgtctc atcatacgac
    13081 gaactagttg ttgtatcgtc ccatgtactt gtcgtagtgg tttcattcaa actttccgtt
    13141 gttgttggtt cagatgtcga gactgaagta gttggtgttg tttcttctac agtactagaa
    13201 cttgaacttg gtgcacggta gctggaacta ttcacaatac ctgtagtagt cgcgacaatc
    13261 gtcgagattg ttaatacagc gattggcttc aaaataggtg ctacttttcg catcttatct
    13321 cttccttcat tgaaatttat tcttgtttcc ttactttact acggacaaat tatacagtct
    13381 accttatttc taccataaat tctttatttt tttcttacgt ttttccgaaa gatttcttta
    13441 attttcctca aaaactacgg ttgatgtttt taagtaagct tttgcttccc gattgatttc
    13501 tttcagatcg catccttgct gcttggcagc gaacacgcaa ccacaataac attggcgata
    13561 aatatcatac tctttgcaca tttgcaaaga gcgttcatag cctttgtttt tcttgaaatc
    13621 acttggcaag tattgtgtcc cgtaaatctt ttggatatcc attccgatct gattgatcaa
    13681 agctgcattt ttctttggcg agatggtcag ggcacttcca aagtaatcgt atcctagttc
    13741 ttgcgctttt tgcgcaacaa gatctaatcg catattgaag catgcactgc agcgagcacc
    13801 accttctttt tcgttttcaa gatggtttgt taaaaccatt ttggtgaatt catttggacg
    13861 gtattcatca acgattagcg caacatgatg gtcagttttc tcattaaatt ggtctacaaa
    13921 tcgtttttgt tcatgtaatc ttcgcaaata ctcactttta ggatgaatat tcgaatttga
    13981 aaaaaataac gtgatctctg catattgaga catgaattcc aatgtgtgcg tactgcaagg
    14041 agcacagcat gtatgtatta atatcttagg ctttacttct tctttctccc attgcatgat
    14101 catttttttc agaactgtat cataatttat tttttgattt ttcatttttt ctacgatttg
    14161 ttgagcatta atcaatttgt tattcctcct ccttcttttt tctaggattt tccttattat
    14221 aagccatttc tattttaatc gaaagctgta ttgttatctg tttgataatt tctttgagta
    14281 ttcctaattc cccttgtata ctggtagaaa cgactattgt caggaggata gtactgtgca
    14341 tgttgattta ttctttcgaa ggctgcagcg gcgaggacag aagtttgctg ccaatcattt
    14401 ctcatcgatc caaatcatcg ttttttatta tatattgatg acggtcttat cactcgttct
    14461 attttatatg ccgatttttc gcgaaccaga tagccatgtt tcttttgtgg acatgctgtt
    14521 catggcaatc agtacagtga gtgtgactgg actatcgact tttgatatca attctgtgtt
    14581 caatgataac ggtattatac tgctggaaat attatttcaa gttggtggtt tggggatcat
    14641 gatgatttct actgcttttg tcattttttc taaacgacgg atcacactga aacagcgaca
    14701 gctgatcatg acggatatga atcaaccgcg tttgtctggt atcgtccgac tgattcggat
    14761 cacttttgct attttaatct ggtttcaatt actttttggg acattctttt ctatttattt
    14821 ttattacaga ggctattttg atcgttggcg tgatgccgtt ttttacggtt tttatcaggc
    14881 gatatcggct gtcacgaact ctgggtttga cgtcactggg gattccatca agccctttgc
    14941 acatgactat tttttcttga tcctgatcat gtttttgatt tttgtcggag gaattggttt
    15001 tcctgtattg atggagtgcc gggaatggct attatacaaa cgttccaatg cgaagcttcc
    15061 gtttcgtttt tccttgttta ccaaattagc tgtgttagct tttgttatct tgtttgtttc
    15121 gggaactgtc ttgatttatc tattggaaaa ggaccattta ttccaagatt ccaatatgag
    15181 tgtcaaatgg atcaattcga tgttttattc gattacgact cgtaatgctg gtctgcagat
    15241 tcacgatttg ggtgattttc aaatcacaac actgatcatt ttttctttac tgatgtttat
    15301 cggatgcagt cctagttctg taggcggcgg gattcgaaca actactgtag caatcatcgg
    15361 tttgtatcta tattccttcc tcaaaagtga agataacatc aatatttttg gacggagaat
    15421 cgatcaagat gatgtgcgaa aatcagtcgt tgtctttatg ctttctcttg gtatgtgttt
    15481 cttttgtatc gtttttttat ctgctacaga agaacaaacg ctgatctcga tcatcatcga
    15541 agtaacttct gcgtttggaa caactggttt atctttaggg attaccggag acttgtctgt
    15601 tgtgggcaaa atcacgattg ctacactgat gtttattggg cggatcggaa tgctatatac
    15661 attgatgtta ttcgtgccaa aagaaacacg agatctaggc tatgaatatc caagcgagaa
    15721 aattattatc ggttaaaatg ggaatatagg taagagggaa taataaaatc acagcagctt
    15781 gaaacaatca ttttgtttca agctgttttt ttgttaaatc atgcgatttt gtccgatttc
    15841 atgcactttc agccgtaacc ttttcttaag aataagaaaa gcaatttaac ctttttttca
    15901 acatatggta tgattagttg aatttattcg tcagcaaatc gtttttggag gttacataat
    15961 gggaatacgc agtcattttg cgattgcagt tggaaaaacg tcgcaatggg cattaaaaac
    16021 tttttttaaa ggcggatcaa gtttaccagg taaactagcg ctgaaagtcg atccacatat
    16081 actagatagt ttggcaaaag actaccaagt cgtcgttgtc accggaacaa acggtaaaac
    16141 attgactacc gctttaacag tcaatatttt gcgccagcaa ttcgatgaag ttctaaccaa
    16201 ccctactggt gcgaatatgg tacagggaat tgtatcgact ttcttgcagg caaaaccaaa
    16261 aaaaggacag aaaaagtttg ctgtcctaga aatagatgaa gcaagtttga gcaaagtcac
    16321 agaatatatg aaaccagaac tgttcttatt tacaaatatt ttccgtgatc aaatggatcg
    16381 gtatggagaa atctatacga cctataaaat gattgtagac ggtgccgcaa agtcaccaaa
    16441 tgcaacgatt atcagtaacg gtgattcacc aatcttcaat tctatcgaaa cagtcaatcc
    16501 tagaaaatat tatggctttg accatgaaga agatcgtgaa caaatggctc attacaatac
    16561 agacggtgtc ttatgtccaa attgtcatca catcttgcat tataaaatga tcacttatgc
    16621 aaacttaggg aaatattact gtccaaattg tgacttcaaa cgtcctgaat tggattatcg
    16681 attaactgat atggtacgga tggacaatgt gtcagcagat ttcgtgatcg atggtcatga
    16741 atacggaatc gaagttggcg gtatgtataa tgtctacaat gctttagcag ctactgcagt
    16801 ggcagagtac ttcaatgtcg atcctgataa aatcaaacaa ggtttaggat atgacgagaa
    16861 agtattcggc cgacaagaag tcatcaatat caatgggaaa aaatgtacat tagtacttgt
    16921 caaaaatcct gtaggtatca atcaagtaat cgatatgatt ggtctagctc cttatccatt
    16981 ttctttagtg gctttattaa atgccaatta cgcagacgga atcgatgtca gctggatttg
    17041 ggatggtaat tttgaaaact ttgccgatat ggatatccca gctgttattt ctggaggaga
    17101 ccgtcataca gatatgactt tacgtctaaa agttgccggg attccagaaa ataaattgac
    17161 agaaacaaaa gaattaccag aagtaatcga aaaaatcaaa gaattgccaa ctgagcatgt
    17221 ctatatttta gctacttaca ctgctgtatt gcagcttcgt aaagaactag ctgctcaagg
    17281 atttatcaaa ggaggaatga accgtggcta attatgaact caatatcgcc cacctttatg
    17341 gaaatttgat gaacacatat ggtgataacg gaaacctttt gatgttgaaa tatatagcag
    17401 aaaaaatggg ggtttcttgc catacggaga tcgttagtat acatgaacct tttgatgctg
    17461 ataaatatga cttggttttc tttggcggtg gtcaagactt tgagcaatta atcatttcaa
    17521 aagacatcca gaaaaagaaa gattctttga tcaactatat cgaaaatgat ggcgtcatgt
    17581 tagccatttg tggtggctac caattgctag gtcactacta catgggagct aatggagaaa
    17641 agatccaagg aatcagtgca ctggatcact acacgttaag tcaggaaaat aaccggttta
    17701 tcggtgatat cgttatccat aacgaagaat tcaatgaaac ttattatgga tttgaaaacc
    17761 acaatggtcg gactttctta ggtgaaggtg aacgaccttt ggggaaagtg gtacaaggtc
    17821 aaggaaataa tggtgaagac caatctgaag gtgtcattta ccgaaatgtc ttcggttctt
    17881 atttccatgg acctatcctt gcaagaaatg agaacctggc agctcgtttg atccgcctag
    17941 ctttagaaca acgttacggt aaagaattgg atctgcccta tcttgaagga caaacagcct
    18001 agttattcga aaaaggggaa tgtgacaaaa atttcgtcac attccccttt ttcgtatcct
    18061 attttaagcg acttgcttgg cataacggtt cacgttttgc ttgatattcc cgattgtttt
    18121 cggatcattg attcctgtga cttcttgaat caattgttcc aagttttcat ggatcttcat
    18181 ttcatgcaat tgacggcttt gttcatcttc aggatcatag taattaaaaa taatccccat
    18241 tgttgccgtc aaatgtgggc aagtcaagtt atgttcttgt agttctctca ctggacgtgt
    18301 aaatctttct tgataaccta acttacgtaa tggtgtccga gcgacacgtg tgatcgcatc
    18361 agagatattt ttgttttgga agcgatgaat gattttttca atatacgcat gatgctgctc
    18421 tgcatcaaac ccccatttgg caatcagcaa acttcctgtt tcctgcaaaa ctgattttaa
    18481 ttgtgccaca actaacgcat cttgcattgc ttcatcaatg gtctggtaac ctaacaaggc
    18541 acctgtataa gcgacagtcg catgaccagt attgacacta aatagtttgc gttcgatata
    18601 tggttctaga tcatctacat ataaaacccc ttttaattgg atttttttat tttttctttg
    18661 gctatcgtca atgacccatt ctttgaaagg ttccacttgg acgaataaag gatcttcatg
    18721 gtgttgtaat gggacgattc gatcgactgc tgcatttgga aagccgatat atttgtcagt
    18781 aaatgatgtt tccggaagat atttatacac ttctttttct agaaatgctg aaccgccaat
    18841 catattttca caggcaatga tatctaaaga tgttgtgctt ccttcctttt ctctttcttg
    18901 gatacctttt gcaatcaact cagcaataaa aggtaagata ttcgggccaa tggcggtagt
    18961 aactaaatct gcttcagcga tttcttggat tactttttct ggatttgttt gattgttgat
    19021 tcctttgaca ttttttacag tgattttttc ttttgattca tctgctaatt cgatttcgta
    19081 ttcttttctt tcatttaaag catcaatgat cgtgtgattc acatctacga aagtaatctc
    19141 aaatccatta gctgccaaaa cctctccaat aaatcctcga ccgatatttc ctgcaccaaa
    19201 atgtactgct ctcatttttc tctctcctta agcaattgct agattttccg ttacttcttc
    19261 tttgctgagc gcgtctgcta gctggacaac attgtccata tcactgcaat aaagtgcgat
    19321 ttgctgtaca agttgcaaat gctcatctcc gactcctgca ataccgaaca aaacagtcgc
    19381 aatcttttct tcttcttcgg taccaaaatc tacaccatct ggtacttgaa cgacacagat
    19441 gccggatttt ttcacatatt tttttgcttc atctgttcca tgaggaatcg cgataaaatt
    19501 ccccatataa acagataaca ttttgtctct atctaccatg gcatcgatat attcctcatc
    19561 aacgcaccct gcttctacaa gcatctgacc gcaatagcgg atcgcttctt ctttggtttt
    19621 aaaagatcga ttgagctcga tcatgtcgaa tggcaaactt tgcatgctgt tttcctccct
    19681 taagctgtct gtttcaaata ttgtgcaatc gattcgtatt tttgcggatt gaccatgctg
    19741 ttgactgata aatgaatgga ttgaggtgca gccatctgta ctttttccgc taaactttct
    19801 ttggctacga tcagtgaatc aggttcatct tttaaatctt ggatattgac ttttcttaac
    19861 gggatagtta aatggttctt gtctaatata tctttgagca cggtcatccc cattgttgct
    19921 gatccggaac gatcatcgtg gacaagtaga atctctttga tttgtttgat gtttgctgaa
    19981 agaaactctt ctgctggctc attctcaatt tcagaaactg atgttttctg cttgctgctt
    20041 aattcttgaa tgatttcatc atatcgaggt gaattcaaaa agttttctac tgagacaaaa
    20101 cgcgcgctcg gtgctttttg ttttgctctt tcttgtagtt cgacctgagt aacgatcaat
    20161 gtattcgagt catctgtcag ttggctgatt gcttgattgg tcaccgtttg aggcaagtct
    20221 gcttcctgta ctttttttct caagatcgaa gcgcccatcg cacttgatcc cattcctgca
    20281 tcacaagcaa aaatgatttt ttgtacgcca gagaatgtag ctccttgagg aataccttgg
    20341 gcacctttgg aagcttgctt agctgccttt gtctcttgaa cagatttttc gaagtcttca
    20401 tttgtatctt tcgcatccgc tttcaaaatt actgcagaaa taccaaacga aacagctgcg
    20461 gcaacaatca cgcccaaaat aacaggaagg taagaattga acggtgtcat cgctagaatc
    20521 gcaatgatcg accctggaga agctggcgct cttagtccag catccatcaa ttggaaaatg
    20581 aaacttcctg acattcctcc gcctataact gataagaata ataacggttt catcataacg
    20641 taaggaaaat agatttcatg gatcccgcct aaaaagtgaa tgatcatggc tcctggtgct
    20701 gaagattttg ctgctccttt gccaaacaaa gtaaaagcaa gtaatacgcc aagtcctgga
    20761 ccaggatttg cttcaagcaa gaatagaata gattttccag cctctgctac ttgttcagtt
    20821 cccaatggtg tcaaaatccc atgattgatt gcattattca aaaataagat ttttgctggt
    20881 tcaataaaaa tacttgtcaa tggaatcaaa tgggcagata aaatgatctc tacacctttt
    20941 gccattgctt gagtcaatgc atcgacaact ggaccaatcg cagaaaaacc taataacgct
    21001 aatccaaaac cgataagacc tgctgaaaaa ttattgacta gcatttcaaa accggatttg
    21061 atccgttttt ggaatagctg atcaaatttc ttgatggcat atccaccaag aggtcccatg
    21121 atcatcgcgc ctagcatcat tggaatatct gttccgacaa tcacacccat cgttgcaatt
    21181 gccccaacaa ctgatccgcg gtcaccagca attacttttc cgccagtata accgatcaat
    21241 aaaggaatca gataagttag cattgggctt accatggtag cgaaagcctc atttggtaaa
    21301 taaccatctg ggataaatag agccgttaat acaccccagg caatcagtgc tccaatattt
    21361 ggcatgacca tgcttgataa agtactgcct aatttttgta ccctcgcttt tagcgaaatg
    21421 ttgtttttgg gaatcgtccg ttccattttg tctctccctc tctccttttg atactctaat
    21481 tgtatccgct tactaaaaag agaaatagtc gtactttggc acgaaacttt gtgccaaagg
    21541 tttgagtatg tcagcaaaat aaaaagattt cggtatcaga aaacttcaat tttaaataaa
    21601 actgttattt taattttttt ataatatgca aacaataact tttgttagca tttaatttag
    21661 atgttttcca ttctattatg ttattaaatt ttatattgga ggcctatcta tgacattact
    21721 gatcaaaaac atgaacatga aacgtggtaa aaaacgtgtg attcgacaat tgaatctttt
    21781 agtagaatca ggagaagtag ctgctttgat tgccccgaac ggatttggca aaacaacttt
    21841 gctgaatggc attgcccaac tgctgccaac aacttatgat caattgtccc ttcacaacat
    21901 ctctcctact gcttatacag attatcgccg gtctttcttt tttctagaat caacgaatca
    21961 gttatccgac tatctatcgg ctgttgatta tttgactttg atcaaatact attggcagag
    22021 caaagtagaa tgccaaactg ttttccaacg attgaagatg actgagtacc ttactttgcc
    22081 gattggaaaa atgtctctag gaatgaaaca acatgtcttg cttgctgctt acttgatcag
    22141 tgattcatct gtcatgttat tcgatgaacc gttgaacgga ttagacccag gaagtattga
    22201 tatcttgaat agcctcatca gacaatggca gaaagagggg aagacgattc ttctttcttc
    22261 ccacgctatc gcgaatatcc aatcgatttg ttctaaagca tgttttctaa aaaatggaga
    22321 aatcgtcaca gaatcctcaa atatggaaga gattttagct atttatcgta aattatatga
    22381 ggtgtaacta tgtctttact tacatttgaa cgcaatctct tactaaaaaa caaagtaaac
    22441 tttttatttc ctctattgtt ggtcgtgctc tttgcattcc cacttttttt tgatcataaa
    22501 cttgcttata cagaattcga tgaactgaat cataactatg aagagatgca acgtttgatt
    22561 gaaacgttga aagaagatga gaatgagaaa gaatttgtgg aaagtttaga gaaaagcaac
    22621 aaactgatcg aagcaatctt acatgcaaaa aacacaggga atgtccagca aatggtcgaa
    22681 gcaacttatc attatgaaaa agatatactg gatcgactga tttctggtca aagacaagga
    22741 attccaatca ttgaacaaca aaaacgtgtc gagttgctcc gttatatgaa agaacatcag
    22801 atccaaagat attctatttt tgacttgcca gcgcatctct ctttagcaaa ttactacgaa
    22861 aatatttttt caggaatgat ttctagtttt ttgattttat gtataaccgc cttgtttctt
    22921 tcttccatca tctcttatga aaaaagaaag caggtaatct ctctagtcaa tctattaccg
    22981 gatagtatgg taaagaaaca tagcatccgt tttaccattt attatggtgc agctatgcta
    23041 agtctcgtga tgccattttt gatcgtctct atactagtaa taatcaaaaa tggtttggga
    23101 gacttccgtt atcctgtagg aacgatcatt ggtcaggaga tacgaatcct gccgatgtat
    23161 gagtatcttt tccagagctt tctgttcctg ttgttgtggg tgctcttttt aagtacaatc
    23221 agttttcttc tatctgcttt atttgaacat tctctagtca atcttttagg tacacttctt
    23281 tgtcttttct tagcagagta tcgcttgttt tcttcgattg gatggataga atcaatcagt
    23341 cattacttgc caacttctta tgttgatttt caaaatgtga tcataggagg agatattttc
    23401 tcgccactag cttcagaaca ggttactttc atgaatggta tcttgacact tggtatatgg
    23461 agtatcgttt tattattcat aggtatgggc actatctata taaaaaagag ctattaaaac
    23521 acaaaaataa taggggcggt gacaaaaacc ttgtcaccgt cccctatttc aaataaacgg
    23581 ttttctagaa taaatagttt tcaaaagctt gcatccgcag taataagaac ctcccaacaa
    23641 aaatagctcc tcttattttt atcttggttg aagttattac ttgatgcaag gcagcttttt
    23701 ttactgtgaa cattggttat atatgtccat gttcaaaaat catttggact tcttcaatgg
    23761 tttccgcatc actgagcgcc attacttggt cgatgtctga acagaaaaag gctaaatctt
    23821 ggagcaccgc taactgatgt tcttttttta aagccactac aaataagagt gtcgcgattt
    23881 ttggttcctc ttttgttcca aagtccacac catcaggcac ttggactaaa tagattcctt
    23941 cttctactac ttcttcatct ttgtcagtcc catgtggcaa ggctacgaaa ttcccgatat
    24001 agacactcgc tttttcttgt ctttcgatca ttgattggat atatgccggt ttgattcccc
    24061 cttgttgggt catccactgg ccgatctcgg tcaacgcttc tttccaattt tgataggatt
    24121 gatcgagcaa tattttttct gctggtagct gtatcatctt ttcaccttca tttctttatt
    24181 tcttcaatca ggattttcgc taacaactga taaacgattt ctttatttcc tgagcggaag
    24241 atctcggtgt tcaagtcatt catgatgatt gctccactga tctttcctaa aagaatcccg
    24301 tctttttctt ggattggcga aggcgccagc ataactaaca tacgggacaa atcgactggc
    24361 tgtctatcca tcccttcaat ggtcaacgga tgtttcaaat tgaaaataca aaagatcggt
    24421 ttagaaatca atgagctgga tgtatggaat aaccccatat ttgtatgagg aataccgata
    24481 ggtgcttgtt catatcgctt aagcagccgg cgatgaacca cctcttcatc cgttactagt
    24541 ccttcaggaa aataaggaaa taagctgcga atcgtttcgg aaatcgtctc aggattatcc
    24601 agttcttgga taaaaaaacg accgagtaat tgattgattt gatccatgaa atgcattgtt
    24661 tcctcataag tatcttctat catccactcg ttattgctgt tatacgtaat tttttgcctt
    24721 tttttcttct caatatgcga aaaagcttct tttagctgct tgacttcatc ttctagcagt
    24781 agcggggaga ctaaaatata ttttccaccg tatcctggta aaatagatgt agaaataaca
    24841 acatcatatt cttcttgtaa atcgattttt tttaaatcag caatccgata gaaatgaatt
    24901 tgttggatga agggaaaata ccttttcaat cgtagttcca acatgctagt agaagctaat
    24961 ccacttggcg aaaatcctgc aatactgata ttgctttctt tcggacttcg ttccaatgaa
    25021 ttcgcaaaat gaaggaccat ataagcgatc tcttcttcgg ataatttttt ttcttgaaaa
    25081 atccgctcta ctgctttacg gattgcattc gcaacttcct cgtattgaac catgattttt
    25141 tctaaaatcg gattggtcag tgtctcttct tgtaaaacgg ctcttgaaaa cacaccagat
    25201 aaatgagtca acagcatttt gtacaaagtt tcatcttcat aaaaatggac attcgtctct
    25261 tcacttactt cttgaatcag ttgttttact aaataagcaa gctgtgtatc gaacgtctct
    25321 tcaaagaaat tctgatcaaa tgagttcgtg aagtcattta ataatcctgc aaaaaagacg
    25381 atctcattta ctggataaag ttgttttgtc tcagaagcga tccgtgaaaa caatcgttta
    25441 gctgtctgta gtaattcttt gtttgccaga ctattatatg tctcatttgt cagtaaatga
    25501 tttttcgtca cacgctccat cgtcaatgtc agcatcaaaa ccaaatgttc aagctttcta
    25561 tcacttagat tggtcttttt ttggatcaat tcttccccga ttactttgcg tgcaagagat
    25621 agatgttgcg gatcaacgaa tcgaaaaaaa taattcagtg atgcatcgaa agaaatacta
    25681 tgaaaaagtt catattcatt gatttctaat tctaatacat tcgctgtcag aagccggcgg
    25741 tatttttccg gtccttcgat ctcgtatccc tggttccgaa tgatttccaa aggcagttgg
    25801 cgaatacttt cttccaactg tttgatatct gcataaaaag tggtattact gatgcgatat
    25861 gattccatga aatgagcaag actcaacggc tctgtcgtca gtaacaactc ggctaaaatc
    25921 gcgtgttgtc gtttagcagt ggataagtca ttacttttcc catctgtatt ttcttttaat
    25981 tgctctaata cttcttctga tgcctcaatg acaaatgagc ctctagctgc ttttttcaaa
    26041 gaagcattta ccgatttcaa tgagacttca agattatcta attcgcggta aatagtccgt
    26101 ttactgacct tcaataaatt catcattttt tggatagata caggtgacgg gctactgaga
    26161 aattctgcta ataattgttt ttctctgggc gataaataca tcttatattt ctcccttcac
    26221 gagtttttcg tattcattcg tagctaccca atgttcaact agaactagcc gagggatctt
    26281 ttcttctagc tgttcagtta cagctagttc tctttgtgcg atataaatcg tttcttcttg
    26341 gattttgatt ttttctattg attcttttga gataacaaac tgttttttcg ctttttttgc
    26401 taattgactt aaaatcgtca tgcccatagt ttgtgagccg cgtctgttgt ttttatacaa
    26461 aaatacaata ttagcaggcg acgttttttg ttctgtgata tctgctatct cttttttttc
    26521 ttcccgcttt ggaaattgga tcgcttcttt tattcgtgac agcaagatat ctgtttccaa
    26581 aaagtgatcc agtacataga tttgactttg aggtactttt tctcttgcaa gacccgctag
    26641 ttcatgttgc acgataacca gctgatttac ttggttattc aattcataga tagagctgta
    26701 tccgacagaa agatcgattt tttctgctgc taatttcttt ttcagcaggg cggctcccat
    26761 agcacttgat cccatacctg agtcgcaagc aaaaatgacg gaatgaatga tagatggttc
    26821 caagatttct cccctttctt tgaccgtttt gttctctttt tctttatttg gtaatttcaa
    26881 tagtatcgct gcacaaatga aggtcacaaa tgtactgatt gctatcccta tacttacccc
    26941 agctagttgt ggataaggcg cattggcaaa aatcacgagt agtgacccag gcgatacagg
    27001 tgcagctaat cccgtatcta accattgaaa tatcaacgtg ccgcttgccc caccagccat
    27061 tacagctaaa aatagatacg gtcgcagcaa gacaaatgga aaatagattt cgtgaatccc
    27121 gccaatcgca tggatcatca atgctccact cgcatttact ttttcctgtt tttctgcaaa
    27181 acaaaggata gaaagtaaga tccctaaacc aggtccagga tttgcctcca tcaaaaataa
    27241 ggaagagtac ccgactgttt gtgagaattc gattcctaaa ggtgtcaata caccatgatt
    27301 gattgcatta ttgaaaaata gtacttttag aggttctaag atcagactga caagtggtaa
    27361 cagattcatt gtgactagcc aagacacaac ggaggcgagc aacaagtgaa cactatttaa
    27421 aactggttca ataaaaacga ttccaattat acaaataacg ctaccagtca gtcctactag
    27481 taggttgctg acaagcattt catatccagc cttgaatttc acatggaatc tagaaacaaa
    27541 ttgttcatat acgatgccgg caagcggccc gataatcatc gctcctacga tttgtggagc
    27601 attggaacga gcgatcaacc ctaaagaagc aattgcaccg gcgactgccc ctttttgtcc
    27661 ccctaccgat ttcccgcctg aataactgat caagatgggt aaaagcagct ggatcatcca
    27721 atggcatacc tcttctaatg tggtgtgcaa atcgccagac acaccttttg ttgctaatga
    27781 caagattccc caagcgataa acagacttag atttggcatg atcatttcat ttaagtgatg
    27841 tccagctttt ctcagttgtt tcatagacac gcgactgctg ttgtttgctt tccatttgta
    27901 ttccatcttt ttcaccagac ttctatttat tgatggacgg attttatgta gaaaaagcag
    27961 caaacgaaaa accgtctgct gctttcagct atctgggaac tatttgcctg gttcagacgc
    28021 aatgattgct agttcacctt ggaccgccca ctcagaaacg ccatttggaa taatacagct
    28081 tgttcctttt tctaatggat atgtttttcc gtcaacgaca aggtctcctg ctccttcgat
    28141 taccgtcatc aatgtataag gggcttgttt tttgaaagat gtgattcctt taatatccca
    28201 ctcatataca ttgaaaaact cagtttctaa ataagtgacg atcgatgaat tcccttttcg
    28261 gacttctttg atttgtaatt ctggtgtttt cgcagggaca gttgttacat cgatcgattg
    28321 ttggatatgc agctctcttg tttgtccttg cgcatctttt ctgtcgtagt catacacgcg
    28381 gtaagtcgtg tcagaacttt gctgtgtttc taaaatcatg attcctttac caatagcatg
    28441 gatcgttccg cttggtacat aaaagaaatc acctttttta actggtactt tcttcaaaag
    28501 gtcatcccag cgcccatctt tgatcatctc agctagttct tctcttgtct ttgcatgatg
    28561 accatagatg atttctgcac caggttcagc atcgatgata taccagcatt cagtttttcc
    28621 taattcacct tcatgtttca tcccataggc atcatctgga tgtacttgta cagatagatc
    28681 atcttctgcg tctaagatct tgatcaataa tggaaacact ggttctgaag gatggccaaa
    28741 caattccttg tgttctgacc atagttcatc taatcttttc cctttgaatt cgccattttc
    28801 tactacactg acaccatgag gatgcgcact gatcgcccaa tcttctccga ttttatcgtt
    28861 agggatatca aaaccaaaga ctgaacgtaa acgacttcct ccccaaattt tttcttgaaa
    28921 aactggtttt aaaaacatag gttcctgcat aattcaaact cctctcattt ttcatagcta
    28981 ttatagcatt atttcggtaa taccgctttc tctttcaaaa agttttcaac aatttcatct
    29041 cgacatatga gatactccgc acgatgatcg acaggatgta cgcgatttga caaaaatatc
    29101 aacgcttctt gtgtttttat atcaatcaag aaaaacgtac ctgtataacc agtatgaaaa
    29161 agaatcgcat gaccgtcttc tacatccttt tttaagtccc atcctaaaga acgatagcca
    29221 ttttttttcg gtgtttgatc ttgcagtaaa gaatcaatcg tctcttcttc taaaaaacga
    29281 ccattacgga tttttccctt gttcaaatac atttggacaa aagtaatgct gtctttcaaa
    29341 tcaataaaga gacccgcgtt acctgcatgt tcagccaaaa ctcttgcttt cggatcatga
    29401 gtttgtccac gcaaaacctc acccgaaggc agttgttctg tgggaacgat ttttttggaa
    29461 ggaaaaggaa gaaataagct gttcatcatt cctaatggtt ccaatacttg ttcttgaaag
    29521 atttccactg cagtttcttg gtaaatttcc tctagcatca acccaagaag aatcgtaccg
    29581 gcatctgtat attttacttc ttttcctagt tgctcacctg gttctagctt caaataagcg
    29641 gcgatcaatt cttcctgaga tagcttatct ctgtttggta tccatgtttt gatatcagaa
    29701 gtatgtgtca gtaaatgacg caaagtgatt gtctgatttt caaattcagg aagatattta
    29761 tgaagcggtt gatcgagttc tatctttcca tcttctaata gacgtaaaac taatgaagtg
    29821 gttgcaacga ctttcgtcag tgaggctgca tcaaacaaca gatcttctgt catcagctgc
    29881 ttttcaggaa cgacttgggc aaagccggct gtaaatgttt ctacttgatt ttcttttatg
    29941 aaggcgactg ctacacctgg ataaaatcct tcttccatct ttttcaaaat aagctgtttc
    30001 gtgtgtggat acatcttttt ctcctgcttt tctatcagat tcttacagtc caagcttaaa
    30061 gcttaatcta tgaggaatca acctttttta cacaaaaaaa ctgcgcgaaa aaccgcgcag
    30121 tttcccccgg tatactattt tctctttcta tctctagaat aagcgatagt atgaccgttc
    30181 ataaaatgac gagacatgcg acaatcgtta agaaagaaaa agttaagcgt cgcatcgaat
    30241 gtcagtttta ttcttttctt ttggctcact gacgaaccac cattcgattc ctatagcatc
    30301 atagattgtg agtactgtgt gctttttgtc taagaagaaa tcaactgata gttgctgcaa
    30361 gtgagcaatc agtccttcca tgctttcagt atcgatcatg aatttcagaa aatcaagtcc
    30421 aatcacttca tctgtaggca aatcaattgc gcctccgcta gcttctgtca aaccaacatg
    30481 gaaatctcct tcattcaata catggatgcc ctcttcttca ttatgtacct tcaaaccaag
    30541 tacatgatta agaaattggc gttcttttgt taagttagta acatttaaat ggattttttc
    30601 aaaataagaa cctgttgata gtttactgaa tttttcttca gattttctta ataatgcttc
    30661 ttgatccatt gtttctggaa tttctctttg gtcgttctta ttctcttcat ggtaaatttc
    30721 caattcattc tcttctgggt ctacgagcaa aatccccata cgtccatgat cttctaaagc
    30781 ttctttgatt ggataattca ttttacggat acgacaaagg atatctgcca tttcttctgt
    30841 gctagggata atcaatgaaa aacggttcag ctttttgatc acccccatgt gatcattcgc
    30901 tctaggactt tcttccagca gcaacatttc acttccagct tcttctgttc ctaaaatggc
    30961 taattcgttt tcttctcttt tcaaatcaaa gccaacaacg ttcttgtaaa aatcaatcat
    31021 tttatctcgg tctttcaccc gaatggctac actttttaaa taggtggcag cccccaattg
    31081 aaaatctttc atatttcttg ctcccctcta cgtcaagctt tattttaacg atggattctt
    31141 cttctttcaa gcaataactt tgattttgtt aaaaaaaatg tgagaaaatt cgcattttgc
    31201 ttgttttttg taaattaatg agtaaaaact cttataaaaa gaggttgtga aaaagctgtt
    31261 ctgcatcaag taataagaac agccaaacaa aaatagctcc tcctattttt cgtttggttg
    31321 ggcttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt gtgaaaaagt
    31381 cgcttagttt cgagtagtaa gaaaaatttt gtgaaaatgg ctttctacat ttttgcataa
    31441 atttggctta ataccgagaa actggctttt gaacaccgtt taccaagagg ttgtgagcct
    31501 gccgtttaac tccgagtcac aaggagcaat ttcaaaaaac agcttctcag gtttgttgac
    31561 tattgtgact tgtgaccgag gagttggcag gagaacaccg tttaaggaag aggttgtaaa
    31621 atcagcggtt tgacctgagt attagagata caaaacggaa aaatagcttc tcatattttg
    31681 ccgttttttg agctaatacc gaaggacagc tgattgaaca ccgtttattc ggaaaaaggg
    31741 actgtgacac gacttttgtc acagccccta aaaaaaataa taaatttgta ctattctatg
    31801 aagcttcttc ttcagaaaac tgactgttat aaagatctgc atagaatccg tctttttcca
    31861 tcaatgtatc gtggtttcct gtttctacga tcgaaccatg attcatcaca ataatgttgt
    31921 ctgcatcgcg tattgtagac aagcggtgag caacaacgaa acttgtccgg ttttccaata
    31981 ggcggttcat cgctttttga atcagtattt ctgttcgtgt atctacacta gatgttgctt
    32041 catcaaggat caggacatct ggatttgcta agaatgcccg cgcaattgtg attagctgac
    32101 gctgcccttg cgaaatattg cttgcatcct cgtttaatac agtgttatat ccttctggca
    32161 atttacgaac aaaatcgtct acgtgagcag ctttagcagc ctcaatgatt tgttcgtctg
    32221 ttgcatcgtc gttcccatat ttgatattgt catagatact tcctgtaaac agccaagtat
    32281 cttgcagtac cattgaaaac tgtgcgcgca attcatcacg tgaaagatca cgggtatcta
    32341 caccatcgta acgaatacta cctccagaaa catcgtagaa ccgttcaaga aggttgatca
    32401 gtgtcgtctt ccctgcacca gtcggaccta caatagcgac catctcacca ggtttgacat
    32461 ccaagttaaa atcagtcatt agcaagttat ctggtgtgta gccgaattga acattttcaa
    32521 aacgaacttt gtatggtgta tctttttctt ctggaaggcc agatttttca ttggacatct
    32581 cttcttcatc caacacttca aatacccgtt cggctgaagc aactgttgat tggatagtgt
    32641 tcatcaaact tgcaagttga gtgattggtt gagagaactg tgttgtatat tgcaagaacg
    32701 cttgaacatc ccctaatgtc atgttcccat ttgcaacttt tactccgcct agtacagcga
    32761 cgaacacata gcctagattt ttaacgaaat tcatcaacgg catgatgatt gccgaaataa
    32821 attgagcttt ccaaccagcg gcatacagat tctgattttc tttttcaaat acttcctggt
    32881 ctttttcagt atgattgaat gttttaacaa tggtatgacc accatatgtt tcttctactt
    32941 ggttattcaa taaacctaaa cttttttgct gatctgcgaa aaacacttgt gatttcggcg
    33001 ctacgatcat cacgatgatc aagcttaaag ggatcatcaa taacgcgact aacgtcaatt
    33061 gccagctgat tgaaagcatc atcacgatga ccccaatcaa tgtgactgca ctagttacaa
    33121 attgagtcaa attttgctgc agcgtgcttg cgatgttatc catatcattg attgctcgag
    33181 acatgatatc cccatttgta tgtgtatcat aataggaaat cggtacacga ttcattttgg
    33241 cttccaaatc atgacgtaat tcataaactg ttcgttggga aacacgtgtc ataataaatt
    33301 gctgtaaaaa gttgaataca gcagaaatca aatacatcac gattactgtc gcaatgatct
    33361 gcgcgatttt atcaaagtct atcggaaatt ttgttacttg ttggccttgt tgcatctgtt
    33421 gagcgccagc cattacacct ttgaatattt ctgtggttgc tttccccaag acctttggtg
    33481 tttggatttg gaagatcacg gctgctattg ctagtacaaa tacagcgatg atcgcaacca
    33541 tacgtttaga catatagcca aacaatcggc gtaccgttcc ccagaaattt ttaggctttt
    33601 caccttttac accgagattt ctgccaggtc caccatgtcc tggaccgcct gctggtccat
    33661 gagagggacg tgtgtttgtt ttactcatgc taagtcctcc tctcttagtt gtgaatgaac
    33721 gatttcttga taagtttcgt ttgttgctaa tagttcttca tgtgttcctt tgccaaccag
    33781 ttttccttca tctagcacaa ggatcatatc tgcatccatt actgtactta ctcgttgagc
    33841 aactaaaacg gtgatacttt ctttcatatt cgttttcaat gcttggcgaa gattggcatc
    33901 cgttttgaaa tccaacgctg agaaggaatc atcaaacaca tagatatctg ctgttttgac
    33961 taatgcccgt gcaattgcca gacgctgtct ttgtccacca gagaagtttc ctcctccttg
    34021 ttccacatgg ctatctaagc catcttccat ctctgaaaca aaatctttag cttgtgcgat
    34081 ttctaatgct ttccaaatca tttcatctgt tgcatccggc ttaccatact gcatattgtc
    34141 tcggatcgtt ccagagaaca gaactgcttt ttgaggaaca aagcccatta attctcgcaa
    34201 attatattga gtcatgtcac taatgtccgt tccatttatt tggatcgaac cagattcgat
    34261 gtcatataat cgagggatca aattgactaa ggtcgtttta cctgaaccag tcccccctat
    34321 gattgcgacg atctcgcccg acttggcttg gaaatcaata tcttccaatg caagtttttc
    34381 tgctccatga tatcgataat tgacatgatt gaaggccaat gttgcgtttt ttccagcaaa
    34441 agaaactgtt ttaggatttt cagggtcatg gataccgatt ttttcatcca acacttcatt
    34501 aatacggtca gctgaagctt gtgcacgagg caccatgata aaaatagcgg aaagcatcat
    34561 aaagctgatc aagatctgca tcgcataagt cataaatgca atcagattac cgacttccaa
    34621 agtcatatct gctatgtagt gtccaccaaa ccaagtgatt gctacgtttg taccgctcat
    34681 gatcaatgtc atcattggca tcatcaatgc gacgatcgta ttaactttga ttgccgtatt
    34741 tgtataatct ttattcgcta aatcaaaacg attttcttca aagcgtgtct tatcgaatgc
    34801 tcgaatcact ctgacccctg tcaatccttc tcgaaatacc aggtttaaac ggtcagtttt
    34861 cttttgcata cttttgaata atggaacagc aaagtacatg attccgccga tcaaaataat
    34921 cattactggg atgacaacta agaagatttt tgtcaactga tgatcttttt gataagcaag
    34981 tatgctcgcg ccaatcaacg tgattggtgc attgatcatc atacgtaaaa acatttgtgt
    35041 aaccatttgg atttgagtca catcattggt cgttcttgtg atcaaagagg ccgttccata
    35101 tttatcaaac gcatcttttg tcagactctc tgatttttta tagacatccg tacgcaattg
    35161 cttacccagt ttctgtgatt cacgagtagc aaaaaatgta tttgcgatag cagctaagat
    35221 actgatcaaa gaaaagccga tcatcacaaa acctgtatgc caaatataat cgacatctcc
    35281 ttgcgctacc cctttatcaa taatattgga ggtaagtgtc ggcaaatata aatctgccag
    35341 tacttggatc accatgaaaa ctgcagctgc aattgctgaa gtcaaggaga tccgttttac
    35401 gatttttagc atctagttcc cttctttcta tttatatact ccgtttttca gccaagaaag
    35461 tttcaaattg aattcactga ttgcttgctc tactgagtaa tcttcagatg ttgaaaataa
    35521 gcgatacgaa tgcgcaattg ttgtaaatac agtattcatc actaattgga tcagtaattc
    35581 caattcatga tcatttttta ctttcagctt cgtccgatcg atcaattcaa gcaactcttt
    35641 tgcatcttgt ttgtgttctt tatgtggatc gtgaggcgtt ttttggcgac tcgtatgagg
    35701 agcgactttt cttgaggcac ggtaatccat gttcataaac aagttacgat aaaaagaagc
    35761 attctcgcct tccaaaatct cataaatcat tttagaaaaa taggattcga atcctttgaa
    35821 tagatcacca tcggattctt tcattagttg taacatatct ttagagctgt cacgtctcat
    35881 tgtctcaaag taataaaaat aaagatcctc tttatcttca aaatactgat agaaactgcc
    35941 tctagggata tccgctaatt tgacgatatt agcaatcgaa gcttctttta agggtactct
    36001 agaaaactcg attctcgcag cctcgattag tcttttttgt ttttctttag gcaaatggaa
    36061 aaatgtctgt gtcggcatat ggattctcct ttctttcaag atgacacatt gtcatatgac
    36121 gctatgtcat tataacacct cctacctgtt ttgcaagaca tttgcatagt ttttttcatt
    36181 atcatccgat acattaaaaa agtgataaga ggaatccttc catttgaatt aatgagagtt
    36241 gcccattaaa atagccacat actaaacaaa ggatgagata aatggcccaa tcaattagtg
    36301 tccaagactt caataaattg cctctcgatg ctgacagcat cgttttagat acaagaaata
    36361 ccttagatta cacaaaaaac cacttaagcc actcgctttc tatccccgct gctatcttgc
    36421 caagacaatt aaaaaatcta gatccaaaga aactttatta tattctaagc tatacaggca
    36481 ggcgatcaga agcattagcc gatcaactta ctgctaatgg ttttcgtgct gtttatatca
    36541 ttggtgggat ggaagctctt cagtcgagtg ttgcttgaat attgcttgtt agattcaaaa
    36601 gaggctgtga caaaaaatcg tgtcacagcc tcttttatac cctgtctttt tttagttatt
    36661 tattcttcaa ccttatcaat atgacttgat agccttttct ttttcgagta aactgatttt
    36721 gttagtcata gttataacaa tcatagcaat aaaaggagaa ggtaagcata tggcatctgt
    36781 tttagtagtc aaaggtcatc ccctaactgc agaagaatcg cgcacagtta aggcattgac
    36841 gtctttttta acaagttata aagaaaatca tccagatgat gaagtgactg ttttggaact
    36901 ttatcgcgat gatattccgg aaatcgatga agaattatta tcaggttggg aagcattacg
    36961 tgctggtgca gaattcactt ccttatcaga aagtcaacaa caaaaaattg ctcgtttcaa
    37021 tgaattgact gatcagttcc ttgctgctga taaaatcgtt atcgcaaacg ccttatggaa
    37081 tctaaatatc ccaacaaaat taaaagcttg gttcgatacc gtcaatgtag ctggaaaaac
    37141 gttccgctat acagaaaacg ggccagaagg attagtgaca ggtaaaaaag cactgcacat
    37201 ccaatctaat ggcggtgtat acaacggaca agactttgcc tctcaatatg taaaaggtat
    37261 tttaaacttt gtaggcatcg atcaagtaga tcagctattc atcgaaggaa tcgattatga
    37321 ccctgaccgt gcagatgagt tgatgcaaaa tgcattagat aaagctgctg ctttaggtaa
    37381 atcattttaa aaattgagat aaatgcatac aaaagagaca gaggaaaaaa tcttcaaagc
    37441 agcatttgtg ccttggatat tttcccatct gtctcttttt gttattcttt ctgctttttc
    37501 aacggatttt cttcataaag agaagagatt gttgtgtacc attcaaaaac atgagtaatc
    37561 actactttag ctgctgcata aacaggaatc cccaagatca caccgatgat tccgaacaat
    37621 ttcccagaag tcagcagaac taataaaatc gttactggat ggattgctaa ctgattccct
    37681 agtactaatg gagagatcaa gcgtccttct attgtctgct ctactgcaaa aacgatcagt
    37741 actttgatga tcatgaatgg acctgctaca atggctaaaa agatagccgg aatcatcgct
    37801 aaaaatgatc ctaagtaagg gatcaggttt aaaaaacccg caataatccc caacgtgaca
    37861 gcatactcta aaccaatgac cgcaaaacca atcataaaca tgattgccac agcaaaagcc
    37921 acagttagtt gtcctcttat ataagaagaa acttgactat tcatttcact cagcacattc
    37981 aacgtcggtt tttgcatgcg tgtcggtaaa aatttgacaa aataaggtgc taattgttta
    38041 ccgtctttca atagataaaa taagataaac ggcatcgtca gcagagccac taaaatagtc
    38101 gctaccgcgc cgacaaaact tccaagactc tgaactgtac tcttagatat atcttggatc
    38161 atatcgcctg ccgaattcat gaacttatca cctgctgttt ccaactgttc gcgaaattgg
    38221 ttgaacagcg ggtcccgcaa aatctcggtt aatttattat caatcgtatc tacatattga
    38281 gggaagttac tgatgaagct cactgtttgt tcctgaatct tagggatgat cactacgctc
    38341 ccccatgcga ttagtgcaac aaccaaaaca aacagcccaa tgatactgta aagccttggt
    38401 acttttcgct tttcaaagta atcaactacc ggattcatca agtaatacaa gattcctgct
    38461 aaaatgatag gcagacctac gattgctaaa aattgccaga ttggtgcaaa caaatatgaa
    38521 acttttgtaa ataaaaagac gatcagcaat attaacaata caacaagtaa ggctgtgact
    38581 acttgattat ttaaaaacca gcgccaaaac cacgataccg gtctgttctt cttatttttt
    38641 ccttccataa ttcctcctgt tagttataaa aaatttggct tcccaaacca atagcaggca
    38701 gtctatgcgg atgaagatag attccatttg caatttgtcc ttcttctgga caagcatcaa
    38761 aaatcaatga tacgtgagct actgtcttta aattcccatt ggccatcgga ccgacataat
    38821 cgatcgtata tacctgatca tcaaaagcaa ttgttccgcc tgctttcaaa gaaaaaggtt
    38881 cgtcttttga tacttcttga atcaccgaat attttcgtaa ggcagctgtt gctgttttat
    38941 cgaacaaaat cagcatgggt tcttccttgt ttattgcttc tgtcccaatt tctgtaatct
    39001 ttgcctgaat cattgcactc tctcctttaa ttgctttcaa aaacagtata acacattctc
    39061 attctttagc cgtgtggaat aattatgtga tagaataaaa acgaaaacta tttcattaca
    39121 attaggagga atcagctcat atgatcgaaa agataatttt aggaacctat acgcgtcgcg
    39181 aaagtaaagg aatctatacg atcgaccttg atacagaaaa agaagaatta gccaaccttt
    39241 cattagctgt tgaagaaaat agccctacct atgtagcaaa aagtaaagct ggcaatcttt
    39301 acacagttac tagtgtggat ggattaggtg gtgccggtgc gtacgataag gattttcatt
    39361 ttttgaatgc ggtaacagag tctggcgctc ctttgtgtta tgtagcggtt gatgaagcac
    39421 gtcaattact atacggggcg aactatcata aaggtgaagt aaatgtctac catatattag
    39481 gagatggcga actgaaagca gcagattcaa tattccatca agaagcgaca ggtcctcata
    39541 aaaaccaaga tcatgcgcat gtccactata cggatctgac tcctgaccaa cgattagtcg
    39601 tatgtgatct tggtacagat cgtgtgtata cttatgatgt gtccgaaaac ggcaaattga
    39661 atcttgtaac taccttcact gcagagccag gaacaggccc tcgccatctt gtctttcatc
    39721 caaatggaca attcgcttat ttatttggtg aattagacag cacagtccgc gtgctttctt
    39781 ataataaaga aacaggtgct tttgaagaat tacagaaaat atcgaccttg ccagaagaat
    39841 tcgacggtga aaatggaggg gcagctatcc gcatttcaaa tgatggcaag ttcctttatg
    39901 cttctaaccg aggacataac tcgattgctg tattcgcagt ttttgaagat ggttcccaca
    39961 ttcaaaacaa gcaaatcatc tcaacagaag gggattttcc ccgcgatttc gcactagatc
    40021 caagcaataa ttttgtcgtg tgtgccaatc agaacaccga taatctgaca ttatatcgcc
    40081 gtcatcctga aacaggatta ctggaattac tgaaaaaaga tgtctatgta ccagaatgtg
    40141 tctgtgttta ttttgatcgt tagtaagaaa aggagaatga aatgaatcag caagacgtat
    40201 tagacagact acgggaagaa ctaaatattc ctttctttga tgggaaaatc gaagataaag
    40261 agtatagcga agaggaatat cagaaactca aagccgattt acagaactac tttgaacaat
    40321 atgtacagaa tgtagaaaac taatcagctt tccatactat ctgaaaagaa catcaggaca
    40381 agacttttcc gtctatcctg atgttctttt ctacaaataa aaaaccgccg agatggttag
    40441 actcgacgga aaaggagtat ttactcgatt ttgagtaagt acaaggttgt tgttggttat
    40501 aggtatgtca ttatcataaa ggattttgat cactctatca taaaggtaat attacattta
    40561 tattagataa ctctagtttt tattgttatc aaagatttct tttatttttt caacaacaaa
    40621 ttagtcattt tttggatggc agctgtcaat tggtctgtcg cttggtcttg ttttgcttca
    40681 gatgtattga atagatcttc atctacccct gattcaagat cgatactttg gatcatttct
    40741 tcacagcctg ctacatatga aagataagct ttttcaaaat ttttatgaat gcccattgct
    40801 tttgctggtg gacgcaaagt actgactttc ataagcattg cccgatattt ttttgttcct
    40861 tcttcaaata acaggatgat ctcttcaaga gtcgatttgt ccagttcact tgtttttcct
    40921 tcatcaattg cgtttctgat cacttcatat ttcggatgca ttccttctcc gattgcttct
    40981 gtttccttga cgatttgatc gatggactgc acataatagc caatattcgg taacatgttc
    41041 gttttcctac tttctccatt gttgttatta tttattctac ttgtttttat cctcaaatga
    41101 caagtacttg aaaaaattta atggtttcta tacagctcgc cattcttatt cgtgctcaaa
    41161 gaaaccatct gctaaactat attgtttccc tgcgacaatg tcatattgga tcaattgata
    41221 ttcgtcgtaa atctcttgtt gcgagcgatt gaattgcgct tctttatacc actgtccgtt
    41281 ttgatagtac agttctcgtt caaacgccgg aagttcctgt tctaatgata aaagcagctg
    41341 ataaaagcca tttgttgtct gattcgtctg ttccattaga ttcgctgcaa aataaaacgg
    41401 actggtgatt gcatcgtgag tcgtttgctt ttctaattct cctttactgt cgaacataag
    41461 aaattgtgtt tcatgcaatg tttgtttgtc attttttgct tggatcgtat ctgaatagat
    41521 ccctggaaga tgatcccccc aaaaaacaac taaagtcctt ctagaaagat tcttcaattc
    41581 ttccgtgaac tgcttcagtg ccgtgctgct ataggaaata tcttgcagat aattctctaa
    41641 gtcaagtgtc ccacttccat ctgaagtttt tgcaggatag tctagattat catactttcc
    41701 atcgtagggc atatgtgtct gcatcgtgac taaatgaatg aactgaggtg ttttttcttc
    41761 cttgagaagt gtcattactt ctttgtaagc tgactcatca gaaatatatg gattattctc
    41821 tatcgtatcc gtataggtca tcgtacgctc gctgatgaac tggtcaaatc ctaatgtctg
    41881 ataaacatcc tctcttttat acatcgaagt attgtatgga tggatcgctg tcgtctggta
    41941 tgattgtgcg tttaacgctg aaacgataga aggaagctga tccatttttg gtacaagcat
    42001 cgtgtaaggg gtggtgagtt gcgcattaaa taacgccata gaaaaaccag tcaatgcttc
    42061 aaattcgata tttgctgttc caccgccata gttttgagaa agcatattgc cactatatgt
    42121 ttgatcagct acttcataat aatctgccaa tggctcacca gatacttcta cgccgtttaa
    42181 tcgactagga tctgagaaac tttcactcat cacgaacacg atgttcggcg actcttcctc
    42241 tacagtttta tttttttcat cggctagctt ctggtatttt tcagtgattt ctttgatctt
    42301 ttctttcgaa tatccttcag gttcatccat tggttctacc ttcagattgt acaaaaaccc
    42361 accgataaaa ccagtgttat agtagttcat tttctggctg taaggtatcc atagtgccgt
    42421 tttattatat gcttttcgca acaaattatc gggattgttg aaattactga tataccctag
    42481 cagtccaatt gccacaagca gtgtcgttaa tcggatcaat tggaatcgcc ttcctttttt
    42541 caggcttcga aacatgtacc agcaaaacaa tcctatcacg gttcctgcgg cagctaagat
    42601 cactgtaaac agcatagtgc cggtcatatc tttcagcaat ccgatttcag tgatcatctt
    42661 caaatcgtct ggataaatcg gttcttgccg ataactcatt ttcatataat ttgcaaaacc
    42721 taatacaccg atggctacga catacgtaag ggaacctaaa gggacagatc ctgctagtgc
    42781 aatcagaaaa ataagaataa tcagcaagac gagacaggct aagaagaatt tttccgtatg
    42841 ccaagaaaaa gcaaatttca acgcaaggtc tacggataga tcattttgac accactgcaa
    42901 aaataaatta ctaaaaacaa caagaaaaaa gatactgatg attgctgctg ttccttttaa
    42961 aatctttttc tgtttggtcg aaagtctgct tatatatctt ttcaaatgct tgctccttca
    43021 tttctatcaa taaaagaatg ttgcttctct tattttagtt gtacgaaatt cgaaagtaaa
    43081 gaacggaaag aagaattaat gaaatccaaa tattctcttt ctttatggcc tttctggttt
    43141 ctttaataag cggacctttc gtactccaga aattttttct agctgttgtt tcacttgatt
    43201 gagctgttca aaatcagtac tgtctatgtc aatcaatatg tagacatgct cattcttatg
    43261 gttacgcgat atatctgcga tcgctagctc gttctcattc agcagagaaa atatctctgc
    43321 taatatattg gttttctttt gataaaatat agtgaatcga aacggcgctt ggaaaaacat
    43381 tcgtgcggat ggataattga ccgcttctct aaccgtaccg aacaaaagat aatcttttaa
    43441 ggcttcaact gccaaacgtc cgctgtctgc caaagcttcc tgagtcgatc cccctagatg
    43501 aggcaacata agtatacggt cattttctaa gaactcttct tctggaaaat cagtcaagta
    43561 tttagccaga tgttgttttt ccaatgcttg cataacagca tatttatcaa caatttcact
    43621 tcttcctaca ttgataagta cagcatcttt tttcattttt tctatattcg cctgatcgat
    43681 caatcctttt gtatcttctg tcaacggcag catgactacg atgtaatccg aggtagaaag
    43741 aactgtttct aaatctgctt gccgaacata atccaactgg gcatcgcgga tagaataacc
    43801 caagacatcc atccctaagc tatagcaact tagcgctact tttgtgccta tcgctccaag
    43861 accaagaaga ccgatggttt tgccttgcaa ttctcgtccc acataagcac ttcttttgtt
    43921 ttctgcctgt tctaaaatat taggacctgt tagtgtttgt accatacgac ttgcttcgat
    43981 tatcggacgg gaagataaga gcaaacagca caaaacaagc tcttttactg cattagcatt
    44041 tacacctggt gtattcatga cgatcgtccc gttttcagaa gctttttcaa cgttgatcgt
    44101 gttcacccca acaccagctc ttgaaattgc tagcaaatct ggtgtaagcc attcatcttt
    44161 cactttcgta ctacgaataa ctattccttc ggctggcaaa tcatctatta ttttgaaata
    44221 ttccccttgt aacttttcta tctcttgttc tggaatagca tcaatcaaat gaacgtgata
    44281 cataaaaccc cctccttact aacaagtatc tcgaaatttc tgcaattaga caactgttta
    44341 ccatttgact tcctagaagc aaaaagagca gttagagcag agtaggctga gtgataaaaa
    44401 taaggctatg acaagttact gccataagcc ttattttcga gagcaaaata ttgagggtga
    44461 gatatcttga taaatggtgt tccgttagct gacattgata ataagactaa atttcaaaaa
    44521 agttgaaaag caaatttcgt caatctcttc ttatttctta aaactaagtg gctttttcac
    44581 aacctctttt tatctaataa ccactgtttc caactcaact aattttgccc acgtttcaat
    44641 ttgatctgtt gttagattta gcgagacaac ggtatgatga ccgccacctg cctgaatcca
    44701 tgaatggaca ccttcatgga aattcggttt agttttccat aacacacgtg caacaggtaa
    44761 attaggtgct tcagtcgttg gttcaaaggc ttctacttca ttgatcagca gtttataatg
    44821 cgtaccgaaa tctgccatcg atacgactac cccttctcct gctttcccat caaatacaag
    44881 acgcgccgga tcttctctat ctcccattga taaaggagaa acaacgattc ttggtttcgt
    44941 cgcagcaagc gtcggatcta cttccatcat atgggattcc aagattgctt cttggccact
    45001 agctagctcg taagtataat cttccatgaa tcctgtatct ttccctcgag ccatgatttt
    45061 cagcaaccga tcaatcgctg cagttttcca gtcgccttcc ccagcaaaac cgtatccttc
    45121 tgccatcaaa cgttgtacag ctagtccagg tagttgtttc attccataca ggtcttcaaa
    45181 attagtcgta aaagcgttat agcctccttc ttctaagaaa cggcgaatac cgatttcctg
    45241 ctgagcttgt acttttacat gttcctccca tgtcttttct tcataatcac catagtcgaa
    45301 ggtatacaat tccttgtact cttcaaataa ttgatcgact tcttcgtctg atacgcgatc
    45361 gattacttgt acaagatctc cgataccaaa ataatcaaca gtccaaccaa attgaatctg
    45421 tgcttccact ttgtctcctt ctgtgacacc cacgtttctc atgttgtcac caaaacgagc
    45481 cacttttatt ccaaaacttt cattataggc tactgcaaca tccatccaat cagcaatctc
    45541 tttttggatc tcaggtcgtt tccagtagcc aacgacgatt ttattttgtt tatttaatcg
    45601 agcattgatg aacccatatt cgcggtcacc atgagcggat tgatttaaat tcatgaaatc
    45661 catatcgatc gttttccaag gaatgctttc gttatattgc gtagctaaat gaagcaatgg
    45721 tttttgtaga agctttgtcc cgcggatcca catttttgct ggtgagaaag tatgcatcca
    45781 agtgatcaca cctgctactt cttctcgata attgacctct ttcatgattt ttgtgatcgt
    45841 atcagcagta actgctaatt cttgaaggcg gattggataa ggcaattggc cattttcatt
    45901 cagttcatcg accatttctt gtgcatgttt ctttacttct cgcagtgctt cttccccata
    45961 taaatgctgt gatcctacaa caaaccaaaa ttctttttct ccaatattca acataattag
    46021 ccactccttt tatttgtttt gtccgtaata cgcatttttt ccgtgttttc gtaaataatg
    46081 tttatctaaa atccgttgag gcagctcttc tgaaaatgaa ttgagctgtc tggtaaataa
    46141 attcatcttg catacttcat ctagtacgac tgcgttcatt accgcacttt gcgcatcttt
    46201 cccccaagta aatggaccgt gtccgtgtaa aagtacccct ggaattgcta agggatcaat
    46261 tttgcgttct ttgaatgttt ctatgataac ttttcctgtt tcatattcgt acccgctgtc
    46321 gatttcctgt tgtgtcaaaa atcgagcaca aggtaccgat ccataaaaag tatctgcatg
    46381 cgtcgtcccc atcgcaggaa catccaatcc tgcttgtgcc cagatcgtcg cccatgtcga
    46441 gtgagtatgg acgattcctc cgatttgagg aaatgaacga tataaaacag catgagtagg
    46501 cgtatccgaa gagggattga gtttaccttc aatgatatga ttgtccaagt ccacaacgac
    46561 catgtcgtct gctgtcatct cttcataact gactccgcta ggtttgataa cgaaatatcg
    46621 tgtttcagga tcaaaagcgc tcacatttcc ccatgtatat ttgacgagtc cgtgtttagg
    46681 caagtcaaga tttgcttggt atacttcttc tttcagttgt tccagcattt tctatcactc
    46741 ctttttcttg caattgatga atcgctgttt tttcaatgtc gatcccctca cggtaacgtc
    46801 tcataaatat ctgatagcct gctatttctt ctgctgaagg tgtgatggtg attccttggt
    46861 cttgtccaaa cacgtcttct gccaagaagt tttctaaaga cttcccatgt cgatccatca
    46921 tataggctgc taataacgcg attccccacg ctccaccttc tccggctgtg tccatcactg
    46981 taactggtgc ctccatagca gatgctagaa tccgctgtcc aacttctggt gttttaaaaa
    47041 tccccccatg ccccactaaa cgatcaattt ggacattctc agatttcaat atatccattc
    47101 cgattctcat tgcaccaaaa gcactggcta aatggatccg catgaaattc gctaaatcaa
    47161 aacggctacc tggtgtacgt acaaataatg gccttccttc atttactcct gtaatgtttt
    47221 caccggaaaa ataaccataa gaaagtaatc ccccgcaatc cgtatcgcct tctagcgctt
    47281 tgttgaataa taccgtgaat aatttatctc tgcttatctc catacccaaa gaattggtaa
    47341 attcttcaaa aatactgacc caagcattga tatccgaaga gcagttattc gtatgaacca
    47401 tgcctactag ttctcctgaa ggtgtagtga ccatgtcgat ttccggatgg acattttcta
    47461 gttctttttc taatacgatc atagcgaagg cggaagtacc agccgaaatg ttccctgtcc
    47521 ctttggctac actgttcgta gcgaccatac cggttcctgc atccccttct ggcggacaaa
    47581 ccgggattcc tggtctcaaa tttcccgtag ggtcgatcag ataagcccct gattcgctta
    47641 acttgccagc ttcttctcct gctactagaa ctttaggcaa aatgtgatcc aagtcaatcg
    47701 ctacgtgcgc tttttcgatt aactgaccaa aaatattttt catttcttga tggtaggttt
    47761 tcgttgaagg atcgatagga aacatgcctg atgcatctcc tacgcctagt actttctcac
    47821 cagtaagctg ccaatggaca taacctgcaa gcgttgtcaa aaaattaatt tctttcacat
    47881 gttcttcttt attcaaaata gattgataca aatgagcgat actccatctc tgcggaatat
    47941 tgtattgaaa tttttccgtt aatattcgtt ctgcttcttc agtgattgta tttcgccaag
    48001 tacgaaatgg tactagtaac tgttccttgc tatcaaatgc tagataaccg tgcatcattg
    48061 cactgaaccc aatcgacccg attgtcgtaa gattctcgcc atagatttcg aatacttctg
    48121 ctgccatttt tcggtaactg acgcgcagtc ctttccaaat atcttctaat gaataggtcc
    48181 agataccatt ttctagtttg ttttcccact cataactacc agcggcaata ggagtaaaag
    48241 atgaatcaat caatacagct ttgatcctag ttgatccaaa ctcaatccct aaagatgtac
    48301 gaccatctat gacatctaac atactttgcg catttacttc cttcataatg atttaactcc
    48361 ctccttctcg tcaaacctga tcaaaccgtc tttttagtag cgcttacaat gattattgta
    48421 tacttttgta cgtacatgtc aagcagttat ttacaagaat acaataaaaa acacttgttt
    48481 tgtacgtaca taagttataa aatgaaattg cttacaaaat ctgatcaacc gccttctcga
    48541 aattctagaa ggagagaata cttatgaaaa aagaaaaaaa agtttcctca tcgtttattt
    48601 atttttttgg cgcatttggc ggcattctat ttggatatga tattggtgtt atgaccggcg
    48661 ccttaccttt tttacagcat gattggggtt tggcaggtaa agcttctttg ataggatgga
    48721 tcacgtcttc ggtcatgtta ggtgcgatcc ttggcggctc tttatctggt cttctttctg
    48781 ataagcttgg acgacgaaaa atgattcttc tttctgcact tatttttatg gctggttctg
    48841 tcctttctgc atctgcccct cacaatggtt cttattttct gattgcagca aggattcttc
    48901 taggtttagc tgttggcgct gcatctgccc tagttcctgc ttatatgtct gaaatggctc
    48961 ctgctagact aaggggaaga ttgtcaggga tcaatcaagt gatgattgct tctggcatgc
    49021 tcctttccta tgttgcagat tatttgctaa aagggttgcc tgaaacgatg gcttggcgcg
    49081 tgatgttagg gctcgctgct gtccccgcgc tgattttatt tttcggtgtt ttagctctac
    49141 cagagtcacc gcgttttctt atgcaatctg gccgcttgga agaggcaaaa agagtattga
    49201 actatattcg gacaccaaaa gaagctgaac aggaattcga acaaatccag ctgaatgtca
    49261 aacaagaaaa gacaaccgga acttcttggc atactttgtt tttagaaaaa tatcgttcct
    49321 tagtcattgc cggtattggt gtagcagtat tccagcaatt tcaaggagct aatgctattt
    49381 tttactatat tccgctgatc gtagaaaaag cgactgggca tgcagcgagc gatgcattga
    49441 tgtggccgat catccaagga atcattttag ttgctggttc tttgctcttt ttggttattg
    49501 cagacaagtt caatcggcga actttattga aaataggcgg tagcgtgatg ggactttctt
    49561 tcatcctacc agctgtttta ggaactgtac tggatgctca tacaaattcg ttgttgattc
    49621 tcttgttttt atgtatttat gtcgcatttt attcttgcac atgggctcca ctgacatggg
    49681 taatcgtagg cgaaatattc ccactagctg tccgcgggcg agcatctggc ctagcctctt
    49741 cttttaattg gattggttct ttcctagttg gcttgctttt tcctgtgatg actgcttcta
    49801 tgtctcaaga aatcgttttc ggcatttttg ggatcatctg ctttttaggg gttttattta
    49861 ttcaagagat cgtaccagaa actcgtggga aatctttaga ggaaatcgaa caaagtgcat
    49921 ctaaaaaaac ttatcctaaa cgtatttcta tccatcattc ttaaagaggt tgtgacagaa
    49981 gtggtcagct tcaagaaata agaaggaacc gcttagtttc cagtcacaag gaacaatttc
    50041 aaaaaacagc ttctcatgtt tgatgaatat tgtgacttgt gaccagttgg taggagaaca
    50101 ccgtttagtg gagaggtggt gaaagaaacg ttcagccttg agcgatgaca aaagctctca
    50161 caaacattgc gacgagtaac cgtaggagca ataagaggcg gtaaaaaccc gtctcttatt
    50221 tttcgttttc tttcactgtt tcccgttcaa ctagtacagg ttcatagaga atatttggct
    50281 gtgcctgtcc tttttcaatc gttgtgacga tccaccgtgc ggcatcttgt cccaactttt
    50341 cttttggatg cgtcaatgtt gtcaattttt tattccctaa atggcttaaa gaagaatcgt
    50401 ctgttcctac gatcgatagg tcatctggaa tatgatagcc attttctgtc aacttatcta
    50461 gcattaaact agctatttga tcgttatagc aaatgatgcc atctaaagct tgttcttctt
    50521 tcaaccgttg tactgttttt tcagcgattg tttctcgtgt ttccgtggtg aaagtaatga
    50581 tatcttccgt caaaaaacgc acattatact gttcacacgc gctgataaaa cctttcatcc
    50641 tgtattttcc ttgaagatcg tcgatttttg tgatgaacaa cagacgctga tgtccttttt
    50701 ttatcaaata ttctgctgcc ataaaaccga ctttcacatc atctaaacaa atataagagg
    50761 catttaactc ttcataagca gcattgatca tcaccatcgg aatgccttgt tctctcaaag
    50821 caacataaag tgctaagttt gggttatact gattactttt cgtaggctca acgatcaaac
    50881 catctacccc ataagcaatc attttcttca aacactcttt ctccaattcg tgatcgttat
    50941 tcgtactggc taaaagcaat gaatacccag attctcgtaa ttcattttcg attcctcgga
    51001 taatcgacgg aaaaatataa tcagagagat atgtggtgat gacaccgatc gtttttgttc
    51061 tgttcaatgg tgttttttct ttcttatagc tgtcatctac atatgtgccc gacccttttt
    51121 ctttacgcag atagccctca tttaccaaca cagcgattgc ttgccgaatc gtatgtctgc
    51181 tgacgtcata tatttcttgc agcttgaatt ctgagggaat ggttgtattt acttcgtatt
    51241 cctcacgaag gatcttttgt tttatctctt ctgcaatatc ttgatatttt gccatttgcc
    51301 ttgccccttt ttatttgtac gtacatatat cataacgagt ctgcaaggtt tattcaagca
    51361 aaaatcaagg tttcttgtgc tcataaggca tacggaacag gttcaccaaa ttctggaaat
    51421 ccttgctcat tccacgtaaa gcattgcgcg ttcgcgtgcc gattaggatt gtctaacgga
    51481 tccccttttt ggttcttctc tggtcgagca tgatagatca aaatatcaaa gcacccgtct
    51541 tctgaaaccg taaacgagtt gtgaccagga ccaaattgct tatttttttc agaagaaacg
    51601 aatactggct ccgataattt atgccatgat tcttttaata aaagattctt gtgctcatca
    51661 gcccacagca ggcccatggc atagttttca tctgttgcac taccagaata cgtaatgaat
    51721 attttcccat tgcgagtaag gactgctgga ccttcattta ctgaaaaacc ccgtttttcc
    51781 cattcatact caggtataga aaggaggatc tgcttcccct ttaacgtcca aggattatcc
    51841 atttcggata gataaagatt agaattccca gtaatttcag gatcttgttg ggcccacaca
    51901 taatatagct ttccttgaga agagaaagtt gttccgtcta aactgaaagt ttcccttttc
    51961 gtttttattt gtcccttttc tatccaatct gtattcattg gatctatatg ctgattttca
    52021 agtacgaaca tgcggtgatg atgagattca tcacgtatag ttttatgatt gcttgcagca
    52081 aagtaaatat accattttcc attgatataa tggacttcag gtgcccagat caattcactc
    52141 atcggtcctt cttcatgagc ctgccataca atcaggcttg cagcatgttc taattcattc
    52201 agtgactttg cccttcttaa ttcaatcact tggtagcctg gaaccgatcc tgtaaaataa
    52261 taataaccat ctgtatgttt atatacccaa ggatctgccc gttgccgaac gataggatta
    52321 ttataaagtg tcttcatcat aacaaatttc ctcacatttt ctttattcta attacattcc
    52381 aagagtattt ttctatccct acatttaatt cgtcatgttt ttctattgaa aaatagttta
    52441 tttcaggttt tattttttct ggttcttcac gtgtattttt gtccaacaga tcgctactgg
    52501 ttaatgtgta gtgctctcct tgatctagca aattgaaatc atgttcaatc gttatctttt
    52561 gttgttcatt tgtgcgattg atcaagaaaa tagtcagctg attgccgtta tctacgatca
    52621 cactgtccac ataaggaaca ttttttatct tttcacaatc ataaacaggg caaatgattt
    52681 gttgtttcaa tacttgacct ttagcatatt tcgataagtg ttgcatcaca taataagttg
    52741 gattcctcca tgcttgtcct ttagcatctg tcagtattaa aggtattgtg tttactaaca
    52801 atgattgaca actaatcttt acgcgatctg cgtgtcgtaa aatagccagc cctaatgaac
    52861 caaataataa tgtatcttcc atagtaaagt aacaccaatc gatgggacta ccgacttcaa
    52921 aatccctatg tcttttttcc ggttgggcat gtacattcca ttcatcaaac gctagataca
    52981 ttgttttctc acttctcaaa tatcctttta cataatcaca agtagcaacg atttcttcaa
    53041 tttgacgatc gaatcgataa gcttttgcaa ggtatgtcgc tgtatcatca cgctcatttt
    53101 taggaggttt agtcaagtct tcttcatcat acttatcaat atagttatgc aaagctaaat
    53161 aatctacatt ctcataagct tcttctaatg cgatacgatc ccattcaggg tacgatggta
    53221 aacgtggcgt agagcttcca actaagattg tttcaattga atcatccact aacttcatga
    53281 cttttgaggc ttcatttgct aacctaccat attcataagc actcttagcc cccacttgcc
    53341 atggaccgtc tagctcattc cctaaacacc ataatttaac gccaaaaggc tttttttgcc
    53401 cattttttat tcttaaatca ctccagaagg ttccttttgg aaaattacaa tattctacta
    53461 aattttttgc ttcatcaatt ccttttgttc ctaaattcac cgtgaatatc ggtttcgctt
    53521 gtacatgact gatccattta aaaaattcgt ggagtccaaa agaatttggt tctatacctc
    53581 gccatgctaa atcaattttt tttggtcgtt gttctttcct acctacagta tccacccaat
    53641 cataaccaga tgtaaagttt cctccaggat agcgaatgac acctaattct aattccttta
    53701 cataagagag gacatcttgt ctaaacccgt caccatcagc tgtttcatgg cccggttcat
    53761 aaatccctgt atagacgaca cttcccatat gctcaacaaa tgagccaaac agccgagaac
    53821 tgatctctcc taccgtaaaa tcctctctga tttttacttt cacttcttcg tccaacagct
    53881 ttccctacct ttcatttcct atagtcaaga taatagatac aagtttccat acgccaccag
    53941 caaagataaa aataaaagga gggaaaagaa atatgagcag tacaaatcct aataacaata
    54001 cgcaacaaag aatatttctc aaaaaatcaa aaaatacttt ccatgcactt tgttcaaaaa
    54061 tttgtaaaaa tgtgatatct ttgttttcag aaatcacata tatccaggat aaaagaaaca
    54121 tggaataaat aagtaaaact acatatccac taattgaaag tacgattgtc tgttcttcta
    54181 ataattgatt aacaagaaaa taaataatga tcgttaacag actaaggaac aagttcttac
    54241 caaaatgttg ctttattcct tgaaagaaaa aataaatgat atttcctgat ccctcacctt
    54301 tccattgcgc cattacataa aaaaacagca catgtagcag gcacgatagt aataacaggc
    54361 aaacacacga ttacccagag aatacctaat aagatgtaat cagaaaccac aatcaactgt
    54421 ccataaagtt tagtctcaac tattttcatc ttcctcactc tttcattcca gacatagctg
    54481 ttccttgaac aaaatatttc tgtgcaaaaa tataaaccac tagtaatggc agcattgaaa
    54541 taaccgttcc agccattaca ggtccataaa aagaaatgtt ctgccctgta aataaagcta
    54601 accctgctgg taaagttctc atttttgaac tacttgtcaa tatcaatgga taaagcaagt
    54661 cattccaact attcatcagc gtgaaaatcc ctaatgataa aagagtaggt ttgctcaatg
    54721 gcaacatgat tttcaaaaaa atattaaact cacttaatcc atcaatgcgt gctgcctctt
    54781 ccaaagaatc tggtaaagta ataaaaaagg aacgcatcat gaagatacca aatgcagttg
    54841 tcatacgagg aatgatcaaa cctgcataag tatcaagcat gccaagcaaa ttgacttcaa
    54901 taaatagagg aatcatgaag acttggaatg ggatcatcat tgtcagcaaa acgaaataga
    54961 acaaaactga ttttcctttg aaacgcatac gagcaaatgc ataccccgca agagaatcaa
    55021 agaatacaga agtgatcact gtccctccag caaaaatcac tgtatttttg atgtaatcta
    55081 ataaagggat cgttgtccaa accttaatat agttatctag ggtatagcta tctgcaaata
    55141 ttctaggcgg aaatgagata atgtcttttt cgtgtttaaa agaagaaata atcagccaca
    55201 aaaaaggaaa cgcaataacc aacaatataa ctagcatact aatcgttcga atgatttttt
    55261 taccactaac tgcttttcga ctattcacag taactgtaat cgagctttct ggtgccatac
    55321 aggtttccct cctatttcat ttgtttttct ttccgtgaca tgtacacatt agtggagata
    55381 gctatagttg caacaatgat aaacaaaacc gaagacagtg ctgatgcata gcccaattca
    55441 taaggtgctg taaatcctcg actgtaaata tattgaacag ctgtttctgt cttaaattgt
    55501 gggccaccag cggttgcaac atatacttgg tcaaacactt gcatcgaacc aatcagattc
    55561 gttaaaatac aaaaacctaa ggagggaacg atctgaggta gcgtaatgtt aaaaaactgc
    55621 tgtcgatttg ttgcaccatc catttgagca gattcataca aagagggaga gattccctga
    55681 atagcagtca agagaatcgt catagtaaca ccaaaattct tccaaacagt catgatggct
    55741 accgtcggca tagcaagggt tggatcgcga aaaaattgag ggatcggcaa gccgacttgt
    55801 gaaaacaagt aaggaatcgc ccctacattc ggatcaagca acatagaaaa aataatcgca
    55861 attgacgtca atgaacaaat aactggaatg taaaatgtcg aacgacaaaa acgattgaat
    55921 ctggtatttt tagataatgc tactgctgct aataaaccaa cgataatttg tgttggcgtt
    55981 tcgagtacgg tgaaatataa agaatgaatc aacgaattaa ctgctcgttc atcactaaat
    56041 atacgtgtga aattttcaaa acttacaaaa tttcttgatg taaagaaaat attcaaatct
    56101 gtaaaactaa tagcaaatgt tcctaaaagc ggtatgacag taaataataa taaaactaaa
    56161 aaagatggag ttaaaaacaa atacgcagca cgatcaggac gattccaata tttggtgaat
    56221 ccgttcatat agtccacctc atctttcatt ttgataaaat atacaatctt ggtttaaacg
    56281 aatctgaata agatatccga acaatcgctg tgatttttgc aataacacct atctgcaaat
    56341 actaggtcga tcattcagat atctgtatct tgccaacagt ctatcctgta taaagttctg
    56401 tactattttt gcagtaattg attgatggca tcatctgcat cgttcatgag tgtctcagga
    56461 tcttctcctg ctaataattt ttcaatcagt ggattgatga tatcgttatt gatcgcagag
    56521 atttgggtaa aacctggtaa atatggctct gcatagtcca tttgtttcga taattcagat
    56581 acaataggat cattttttac ttcttcatct tttgctactg aatccaagta ggcaggaaaa
    56641 ccattttcga tactccattt tttaccaatt tcagttgtat tccaatattt caaaaactca
    56701 tagacagctt cttttttatt attatctgta cttgccggaa tggcatatcc tacgccatct
    56761 aaaatagctg tttttttgtc tgaatcactc ccttgtggta aggtagtcac attataatca
    56821 atctcgtttg ctttcaatcc gttatttaac catggcccat tgatttcaat ggctagttga
    56881 ccagcattca ttaaattgtc catttcggcg ccagaaatcg attctggacc agtcttgtct
    56941 acatggatca ttttttggat cgcttttaac gttttaaggt tctcaggaga cgcaaattca
    57001 gacttagtat aatcatcgtt cactaattta ccgccatttg ctaacatcca gttatataac
    57061 ggtgcagttc catccttatt gaagacaaaa cctgatacat ttttactact atcagttaat
    57121 tttggtgcca tttctgtcaa ttcttcccaa gtagtaggtg gttgttcagt atctaatcca
    57181 gcttgtttaa acaaatcatt attccaatac atatacatgc cttgtacctg catggggaca
    57241 aaatactgtt taccttctac ttcacctaat tcaatagccg tttctttaaa atcagattta
    57301 tctactccat catattccca gaaatcgtct aatggttgta ccgctccgtt ttctacatac
    57361 tgtgcaaaat ctggataatt taatgcaata aagtcaggtg cttttttaga agaaatcgct
    57421 gtaggaagtt tttcattcaa attggcccaa gtcatgatat ccatttcaat tttgatgttt
    57481 ttatcatttg ttttattaaa ttcattaacg atttcttgca atatttcacc atcagatgca
    57541 gtaaacccat tccaaaaagt caaagtcact tctttatcag aatcagattc tgctgaactt
    57601 ccgccaccgc aagctcctaa aatacctgtt gcagctacca acaaagagcc aattaaccat
    57661 tttttacctt tcattttttg ttcctccttc atctgataaa cgacatctga ccacattcca
    57721 agatagcggt ttcaataaac aattgatttt cccatcttca gcttttacat ttgttgaatg
    57781 acttggtttt acttgttcac ttttaggaag attagttgct tttgtatcaa atccactcat
    57841 ttcagaaaaa tcaatcactc cctctaatga taattcagac aagtgaacag ttagattcat
    57901 ttcttcttct ccacggttaa ctgcaaatat gacaagttct ttgtcattta ttacggctat
    57961 actttctaaa tacggcactt cttcaaaatc ttccgtcgca tagtttgctg aacgaatttg
    58021 tgggcttaac acctctcctt gtccatacac agcagcttgc ataaatggat aatagatcgt
    58081 ctgtctccaa gcttctccgt ttgtttctgt cctgattggt gcaataacat ttaccaattg
    58141 agcaagacaa gcaatcttta ctctatctgc atgtttcaat aaagtgatta atagacagcc
    58201 taatagtaat gcatcttcaa aattatagtt atcttctagt aaaggaggag caatctgcca
    58261 aggcgctgct tgctcatctt gttccgctga atgataccaa atattccatt catcaaagga
    58321 caggttgatc tgcttcttac tatgtttctt cgccttgact gtatcgcaca tcgctgtcac
    58381 ttcagaaatg aaccgatcca tgtctaagga acgtgcaaga taatgagaaa gatcattttt
    58441 ttggttgcca taatattgat gcagagacaa ataatctatt tgatcgtacg cttgatcaag
    58501 aactgttaac tcccaatcac caaatgtagg catttgccga ttcgaacttc cgcataaaac
    58561 cacctcaatt gaatcatcta cgagtttcat cgccttagcc gtttcctctg ctaaccgtcc
    58621 atattcttcc gctgttttat gtccaatctg ccaaggaccg tccatttcat tccctaaaca
    58681 ccatgtctta attccaaaag ggctctcttg accattcgaa cgccttaaat cactccaata
    58741 agttccttta ggaaaattac aatattcgac taaattacga gctgcatcta ctccacgagt
    58801 acccagattg acagccatat tgatttcggc ccccacatgc tgacaccagt tataaaattc
    58861 atgaatccca acttcattcg tttcaattgt ccgccaagct aaatccaacc ttctaggtct
    58921 atttgctatg ggcccaatac tgtcttccca acgaaatcct gacacaaaat ttccaccagg
    58981 atatctaatc atgggaatgt tcaattcttt taccaagtga atgacgtctt ggcgaaatcc
    59041 acttttatta gctgatggat gatctggctg ataaatccct tcatatactg ctcgtcccat
    59101 atgttcaata aatgaactgt acaaccgcgg atcaactttg cctacacgct tgacactact
    59161 aatcaacatt gtggcttcca taactgacct cctttaattt atacatgaat aatacacctc
    59221 gttgaaagcg ttgtcaataa tataaatgtt aaacttactt attttttatc gattttaatt
    59281 aaccaaaata ttaataatga ttaaaacaaa taatttaata taacttttat taacaaatat
    59341 gttaatatat aagaaaaacc ttttaagagg tgatatatat gcaactacaa ataaacgaag
    59401 aatccttacc ggtatatgaa gcattagcta gtaaaacaag gatcaagatc atccagctac
    59461 tttccaaaaa aaagatgaat gtcaaagatt tggcaaaaga acttggagtg agcagtgcta
    59521 tcacgacgat gcacgtgaaa aagctagagg aagcaaacat catcaaaaca gaaaaagtag
    59581 gacaacaaaa aatttcgagc cttcgtgtcg ataaaatcga tatcagtttt ccagaaaaaa
    59641 tattcaatgc ttttgatacg aaagaaacat cgatacctat tggtcactat acaaattatg
    59701 caattgaacc aacatgcggt ttagctacga tccatgattt tatcgggaaa gtggatgaac
    59761 cacgctattt tatggatcct cgaaggatgg atgcccgcat tctctggttt accagcggat
    59821 ttgtcgagta tcaggcacct aattttttaa atacagagga tacattggag atgttggaag
    59881 tttctgtgga aatttcttct gaatttcctt tttcaaatga caattggcct tcagatatca
    59941 ctttcagcct aaatggtgtg gagctaggaa catggacgag ccctggagat tttgctgata
    60001 tccgcggtaa atatacgcct gattggtatc cagataatct taatcaatac ggcttgctga
    60061 agacgatccg aattaccaaa cacttgacga atatgaatgg agaacccttg tcaaacatca
    60121 cgatcaacga catccctaaa gagcaagaca cttggcattt gcgaatcgaa gtgaaagacg
    60181 atgccaaaca tgtggggggc tgtactttat ttggtaaagg attcggtaat tacgatcagg
    60241 atatcaaatt aaaagtttac tacagctgat atttttcttt tctattttat aaaacaaaaa
    60301 cagccaatcc ctatgaaggg acggctgttt ttgctttatt gttatttcca gaaatcatcc
    60361 aaaacggaaa ttggcaaatg tcgtttatgt tgtgtcttgt tccaccatgc ttcgattttt
    60421 tcttgtgctt gagcgggaac ttcttttcct tctagataat catcaatttc attatatgtg
    60481 acacctagtg cgacttcatc tgcaatcatt ggtttcccat cttcaagatc tgcagtcgga
    60541 atttttgtgt ataatttttc cggtgcattc aatgcttgaa gcaattgttt cccttgtcgt
    60601 ttgtccaaac ggaataatgg caaaatgtcg gctccaccat caccaaattt cgtgaagaat
    60661 ccagtaatgt tttctgcagc atgatctgtc cctaatacgg ctcctgctct ttctccagct
    60721 acggcatatt gcgtaatcat acgttgacgt gctttgatat ttcctttgtt aaaatcgctg
    60781 attcccacac ctgcttcgct taatacttgt acttgtgcat caacagctgg tttgatattt
    60841 actcgcagac taacatcggg ctggataaag tcaagagcag cttttgcatc ttcttcatct
    60901 gcttgttcac cataaggaag acgaacagcg ataaattgat agttttcatc ttttgtttct
    60961 tcacgcattt cttccatcgt tagttgcgcc aaacggcctg ctaaagtaga atcttggccg
    61021 ccgctgatac ctagtacaaa agttttaaga aacggatatt ttttcaaata tgctttcata
    61081 aagtcaatac ttttacgtat ttcttctttt ggatcaattg ttggtttgac acctaattca
    61141 ttgataattt ctgtctgcag gctcatttat tctcctccta tgcttctgta tgaagttctg
    61201 ctacgctttt tttcattcgt tccatgatag ccattttatg gttccagcat tcagtagaca
    61261 gatcgactgg gtatttttgc ggattcaagt ctcgtttata ctcttcccat agtgaatcta
    61321 gattttcttt tgtatattct ttgatttcgt ttagtgcagg taattcgtaa actctttttc
    61381 cttcgataaa gatatcttgt aaaactgggc gagctgtaaa gtctcgaaca gttttattga
    61441 taaacgtatg cactggatgg aacatgaaga tagcttcttc ttctcgaggg tcttcatccc
    61501 ataatgtcac gtagtctcct tcagatttcc catcaaaatt tcgagtgatg cgccacactt
    61561 gttttttccc tggagtagtt actttttctg cattgcttga taacttgatc gtatccatca
    61621 tttttccttc atcatcttcg atcgatacta gcttgaatac tgcaccaagg gctggctgat
    61681 cataggctgt gatcaatttt gtcccaacac cccatacatc aattttagct ttttgcatct
    61741 ttaaattcaa aatcgttgct tcatccaagt cattcgaagc atagattttt gcttccgtaa
    61801 atccggctgc atctaattgt tcccgaacac gcttagatat ataggccata tctccactgt
    61861 cgatgcgtac gccttggaag ttgattttgt cacctaattc tttcgccacg cgaatcgcac
    61921 ttggcacacc tgatttcaac gtatcataag tgtcgactaa gaacacgcag tctttatggg
    61981 ttttagcgta ggccataaat gcttcataat catttccata agattggact aacgaatgag
    62041 catgggtccc gctagctggt atcccaaata tcttcccagc acgtacattg cttgttgcat
    62101 ctgctccgcc gatatatgcc gctctagttc cccagactgc tgcatccagt tcttgtgccc
    62161 gtctagttcc aaattccaat agtggatctt ctccgatgac agatttgata cgagctgctt
    62221 ttgtcgcgat caacgtttgg aaattgacca tattcaacag tgctgtttct actaattggc
    62281 agtgcgctaa aggcccttcc acttggatta atggttcatt tgcaaaaact agttctcctt
    62341 cacgagcaga acgaactgtt gctttaaatt caaaattttg taaatactcc aaaaaacctt
    62401 caggatagac ttctaatcca cgcaagtaag caatatcgga atcattgaac gtcagattct
    62461 ctaaataatt gactaaccgt tccaatcctg caaaaaccgc gtatccgtgg ttaaaaggca
    62521 tttctcgaaa gtaacattca aaaacagcat gtaaatcagc tcgacctaat tcccagtatg
    62581 tctgcatcat attgatttga tatagatccg tatgcagcgt caaactgtcg tctgggtaag
    62641 tattattcat cttgtattac tcctcttggc aagttttcat ttcctaccca ttataacaaa
    62701 aaaaattaat aggaaaagaa atcttccatt ttttctgaaa aagcacatgt tttacggata
    62761 tttcttgcta aaaatgaact ccatctgcta aaactatcct ttcttattgg tatttaacct
    62821 aaacgagaaa gaatacttat tttattcaat gtatccgaga cacgaagaaa ttagcgtttt
    62881 ctatttttct tacttgataa aataagtaga ttttcctact acaatcgtag ccgttaagat
    62941 accgatgatt gaacaaatat aaccaaatgt ctctacaaca taatcaatgg caaaagtttt
    63001 tgaagcaata atacgtcttt ccttttttgc ttcttatccc caaagaaacg gatataactt
    63061 attatgtatt gaattttttt ggaaaggcga attatgacaa gatatacctt gcgttgaaaa
    63121 aactcgcgga aaaaatatca cacgttttta aaaagataca aagtaagaaa gcagctgtca
    63181 atagaatgga aacaaaaatg gcgagacatc aatcagtctc gccttgtttt ttattgtata
    63241 cattagatat ggagcaggtt accataaaga tgattattag tcgttattaa atagaatcct
    63301 tcgtattttt ttgttctatc actacaatat ctttatttgg acgtttgaat tgtattccgg
    63361 cacgttctag ctcctgtttc actcctacat ggactttgac atcttctcgt gtcattttta
    63421 aaacgtgatg aatcgcatag tcgatttctt gccttgtgat ttttttcttc gtattgatca
    63481 tcacgacttg ctttttatca tatgtgtcta ccaatagcag ttgtgttcga tctaacgaaa
    63541 ataatttgta ataattaata gccgtattcc caaaaaagaa ttccactact ttaggataaa
    63601 atgtcttaat atttaaatta ctattcacag gtgtttcgat tagcttcatc tcattcctct
    63661 tttctatata gtcgatttag atccaatctt aagttatgtt accatctttc ctagcattaa
    63721 ggaatcggtt acaattgaac ctttaaagac aaaaggattt accttttatc acttaatagt
    63781 ataacataat ttcgtgagaa aaaaatacaa ttttttcttg accatctcgt tacgtaaagg
    63841 attatgctta catttgtcag gaggaaaaat aatggagtac acaataaaga aaatgtcaga
    63901 gatatcagga gtcagtccga gaaccttgcg cttttatgat gagattggac tgctaaaacc
    63961 agctaggatc aattcttcag gttatcggat ttatggcaaa aaagaagtcg atcgtctgca
    64021 acacatctta ttttatcgaa caatggcatt caagttggat gatatccaag aggtcttaga
    64081 caatccatct tttgaccacc agaaagcttt aatcaagcat cagcaaatgt tgctggaaaa
    64141 acgggcacaa atcgataccc tcttgacaac tgtccaacag acacttgata tgtacgaagg
    64201 aggaagaaaa atgagtgaca aagaaaaatt tgaagggttt aaacaacaaa agttgaaaga
    64261 aaatgaagaa tcctatggac aagagattcg acaaaaatac ggaaaaaaaa aggttacagc
    64321 atccaatgaa aaatggatga atatggataa agaaacgtat gaagaaatgc aaactgttga
    64381 aaagcagatg ttatttgatc tcactcttta cttaaaagaa ccagaagatg aaagcttagc
    64441 agaccgtatc ttccaagctc ataagaagtg gttctcttac agctggcctg aatatcagcc
    64501 aaaagcgcat aaaggactag gaatgatgta cgaagccgat gaacggttca ctgcatatta
    64561 tgacgagcga agtggtcatg gtgcagcaaa agctttaaat gaaattatcc aaaaaaaggc
    64621 gtaatctttt acatgatcca acaaaaaagt acacgtaaaa tgacctaata acaaaacagc
    64681 agacacccaa gttagatttt tatgctaact tttggtgtct gctccattct ttcacaagtt
    64741 ttttcatcct actttaaata tattcatcgt tgaataaacg tataaggtat tttcacttta
    64801 tccttttttt ctgtaagaaa caattgaaat gccatttctc cgcaagcttc cagatggtgg
    64861 tcgatggttg ggaaaccaag aagctcgctg atcagcaaat tatcgcgtcc aatcaccact
    64921 ggtgtcttat cttgcagata gctttgcaag atgcctgctg caaccatatc cgaatttgta
    64981 aagacaccat caactccaag ctctttaaaa aagaagcctg cttgttttcc tttctctgca
    65041 tctatacaat cccaaaaaac aagtgattca tcaaaagatg gaaaaagttg atgacatagc
    65101 tgcaaagtga tttttgagtt ataacttagc ctgccacttc gccccaacgt gatgcccaat
    65161 tgctttatac cttgctgctt caaataagta agaccttctg taattgattg ttctcgatca
    65221 ataaagacac agcttgcctg ttttcccttg atttcttcac aaaaaactag aggtccatat
    65281 ttttgatatg ccaataaatc atctagtgta ttggcacgag acgtaatgat caatccatcg
    65341 aaagctttag ctgcaaattc ttcaagatac cttcgctctt tttctttatg atagcccgtc
    65401 ggtaaaagtg tcactttgta atcataatca aacgctgctt caatgatccc actgatcaac
    65461 tgatcaaaat acggatgatt ggtataaggc agaatcactc caatgctttt cgtttttcca
    65521 taacttaact gtctggcatt tgcattaggg atataatcga cttctttcat gaccgcaagt
    65581 atttctttcc ttttttcctc atctacatat ggatgtccat tgattacacg tgaaatagta
    65641 gaaactgaat aacctgtgag ctttgcgata tctcgaatgt ttgccactgc tgcttcgcca
    65701 cctatacaaa aagattttct tgtaaatagt ctaccacagc tggaccgcat tcaaaaaact
    65761 gatacatttt tccttcatgc gaaaaactga tccgctgccc gccccaatat atatcttttg
    65821 tcaaattttc gatttcattc attggtattt cttttactat attcctattc aacccttgaa
    65881 aactgtacaa cgttaatacg gatcccttga actcgacaaa cgcataaaaa taattgttcg
    65941 ttgtgccatc tgttatctct acataagtat tcattgcaag ccctcctttt gatactttga
    66001 gtatagtgta tgaaacgcgt ctcatagcaa ggagtttgtt ttgccaaaga aaagttttat
    66061 tcctctttca ttattaccaa agtctcttat tttaaattga atacattata atgatactgt
    66121 aaatatatct ttattattag tgaatg
//
LOCUS       DAZKPE010000010        59730 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000010 DAZKPE010000000
VERSION     DAZKPE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.010"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(451..1761)
                     /locus_tag="ACG930_000717"
     CDS             complement(451..1761)
                     /locus_tag="ACG930_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFQ0517898.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="ACG930_000718"
     CDS             complement(1773..3191)
                     /locus_tag="ACG930_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0517899.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="ACG930_000719"
     CDS             complement(3431..4999)
                     /locus_tag="ACG930_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFQ0517900.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="ACG930_000720"
     CDS             complement(5003..5413)
                     /locus_tag="ACG930_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFQ0517901.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="ACG930_000721"
     CDS             complement(5410..6333)
                     /locus_tag="ACG930_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFQ0517902.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="ACG930_000722"
     CDS             complement(6330..7208)
                     /locus_tag="ACG930_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFQ0517903.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="ACG930_000723"
     CDS             complement(7195..8532)
                     /locus_tag="ACG930_000723"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFQ0517904.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="ACG930_000724"
     CDS             complement(8535..9638)
                     /locus_tag="ACG930_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0517905.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="ACG930_000725"
     CDS             complement(9712..11220)
                     /locus_tag="ACG930_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0517906.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="ACG930_000726"
     CDS             complement(11186..11878)
                     /locus_tag="ACG930_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFQ0517907.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="ACG930_000727"
     CDS             complement(11900..12874)
                     /locus_tag="ACG930_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517908.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="ACG930_000728"
     CDS             13174..14046
                     /locus_tag="ACG930_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517909.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="ACG930_000729"
     CDS             complement(14504..16702)
                     /locus_tag="ACG930_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517910.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="ACG930_000730"
     CDS             16934..17926
                     /locus_tag="ACG930_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0517911.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="ACG930_000731"
                     /pseudo
     CDS             17986..19407
                     /locus_tag="ACG930_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
     gene            19400..20899
                     /locus_tag="ACG930_000732"
     CDS             19400..20899
                     /locus_tag="ACG930_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFQ0517912.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="ACG930_000733"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="ACG930_000733"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFQ0517913.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="ACG930_000734"
     CDS             22491..23174
                     /locus_tag="ACG930_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFQ0517914.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="ACG930_000735"
     CDS             23176..24012
                     /locus_tag="ACG930_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0517915.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="ACG930_000736"
     CDS             24023..25777
                     /locus_tag="ACG930_000736"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517916.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="ACG930_000737"
     CDS             complement(26053..26394)
                     /locus_tag="ACG930_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0517917.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="ACG930_000738"
     CDS             complement(26462..28633)
                     /locus_tag="ACG930_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFQ0517918.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="ACG930_000739"
     CDS             28844..29701
                     /locus_tag="ACG930_000739"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0517919.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="ACG930_000740"
     CDS             complement(29772..30629)
                     /locus_tag="ACG930_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0517920.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="ACG930_000741"
     CDS             complement(30614..33316)
                     /locus_tag="ACG930_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFQ0517921.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="ACG930_000742"
     CDS             complement(33329..34618)
                     /locus_tag="ACG930_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFQ0517922.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="ACG930_000743"
     CDS             34768..35814
                     /locus_tag="ACG930_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0517923.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="ACG930_000744"
     CDS             35816..37969
                     /locus_tag="ACG930_000744"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFQ0517924.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="ACG930_000745"
     CDS             complement(38442..39893)
                     /locus_tag="ACG930_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0517925.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="ACG930_000746"
     CDS             complement(39890..41614)
                     /locus_tag="ACG930_000746"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0517926.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="ACG930_000747"
     CDS             complement(41607..42221)
                     /locus_tag="ACG930_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0517927.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="ACG930_000748"
     CDS             complement(42566..44023)
                     /locus_tag="ACG930_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0517928.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="ACG930_000749"
     CDS             complement(44064..44984)
                     /locus_tag="ACG930_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517929.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="ACG930_000750"
     CDS             complement(44996..45943)
                     /locus_tag="ACG930_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517930.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="ACG930_000751"
     CDS             complement(46422..47141)
                     /locus_tag="ACG930_000751"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFQ0517931.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="ACG930_000752"
     CDS             complement(47190..48836)
                     /locus_tag="ACG930_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0517932.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="ACG930_000753"
     CDS             49015..49605
                     /locus_tag="ACG930_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0517933.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="ACG930_000754"
     CDS             49697..51202
                     /locus_tag="ACG930_000754"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFQ0517934.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="ACG930_000755"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="ACG930_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0517935.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="ACG930_000756"
     CDS             complement(52638..53156)
                     /locus_tag="ACG930_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517936.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="ACG930_000757"
     CDS             complement(53172..53498)
                     /locus_tag="ACG930_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFQ0517937.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="ACG930_000758"
     CDS             complement(53511..55490)
                     /locus_tag="ACG930_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0517938.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="ACG930_000759"
     CDS             complement(55511..55825)
                     /locus_tag="ACG930_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFQ0517939.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="ACG930_000760"
     CDS             55993..56286
                     /locus_tag="ACG930_000760"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFQ0517940.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="ACG930_000761"
     CDS             complement(56364..57476)
                     /locus_tag="ACG930_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0517941.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57629..58477
                     /locus_tag="ACG930_000762"
                     /pseudo
     CDS             57629..58477
                     /locus_tag="ACG930_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(58830..>59730)
                     /locus_tag="ACG930_000763"
     CDS             complement(58830..>59730)
                     /locus_tag="ACG930_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HFQ0517942.1"
                     /translation="QTGLTTGEDGKLAIDGLAPGAYQLVETQAPTGYELDATPIEFEI
                     ERSQTAVVELTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGAD
                     GKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVL
                     TKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTG
                     YELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQ
                     FILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17840 a        12213 c        10446 g        19231 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg ttaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gccctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaagttt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc ataccccgtt
    59641 ggcgcttgag tttctaccag ctgatatgct cctggtgcta aaccgtcaat tgccagtttt
    59701 ccatcttctc ctgtagttag accggtttgt
//
LOCUS       DAZKPE010000011        52196 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000011 DAZKPE010000000
VERSION     DAZKPE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.011"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..367)
                     /locus_tag="ACG930_000764"
     CDS             complement(<1..367)
                     /locus_tag="ACG930_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0517943.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNF"
     gene            complement(520..846)
                     /locus_tag="ACG930_000765"
     CDS             complement(520..846)
                     /locus_tag="ACG930_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0517944.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(858..1058)
                     /locus_tag="ACG930_000766"
     CDS             complement(858..1058)
                     /locus_tag="ACG930_000766"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517945.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            1181..1783
                     /locus_tag="ACG930_000767"
     CDS             1181..1783
                     /locus_tag="ACG930_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0517946.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            1838..3004
                     /locus_tag="ACG930_000768"
     CDS             1838..3004
                     /locus_tag="ACG930_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0517947.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            complement(3093..3485)
                     /gene="rpsI"
                     /locus_tag="ACG930_000769"
     CDS             complement(3093..3485)
                     /gene="rpsI"
                     /locus_tag="ACG930_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFQ0517948.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3501..3929)
                     /gene="rplM"
                     /locus_tag="ACG930_000770"
     CDS             complement(3501..3929)
                     /gene="rplM"
                     /locus_tag="ACG930_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFQ0517949.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4463..4930)
                     /locus_tag="ACG930_000771"
     CDS             complement(4463..4930)
                     /locus_tag="ACG930_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0517950.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(5050..6588)
                     /locus_tag="ACG930_000772"
     CDS             complement(5050..6588)
                     /locus_tag="ACG930_000772"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFQ0517951.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6668..7354
                     /locus_tag="ACG930_000773"
     CDS             6668..7354
                     /locus_tag="ACG930_000773"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFQ0517952.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7555..8082)
                     /gene="msrA"
                     /locus_tag="ACG930_000774"
     CDS             complement(7555..8082)
                     /gene="msrA"
                     /locus_tag="ACG930_000774"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0517953.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8166..8843)
                     /gene="pgmB"
                     /locus_tag="ACG930_000775"
     CDS             complement(8166..8843)
                     /gene="pgmB"
                     /locus_tag="ACG930_000775"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFQ0517954.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8840..9968)
                     /locus_tag="ACG930_000776"
                     /pseudo
     CDS             complement(8840..9968)
                     /locus_tag="ACG930_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(9968..12151)
                     /locus_tag="ACG930_000777"
     CDS             complement(9968..12151)
                     /locus_tag="ACG930_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFQ0517955.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(12148..13173)
                     /locus_tag="ACG930_000778"
     CDS             complement(12148..13173)
                     /locus_tag="ACG930_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0517956.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13218..14045)
                     /locus_tag="ACG930_000779"
     CDS             complement(13218..14045)
                     /locus_tag="ACG930_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0517957.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(14042..15109)
                     /locus_tag="ACG930_000780"
     CDS             complement(14042..15109)
                     /locus_tag="ACG930_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFQ0517958.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(15135..15971)
                     /locus_tag="ACG930_000781"
     CDS             complement(15135..15971)
                     /locus_tag="ACG930_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517959.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15968..16837)
                     /locus_tag="ACG930_000782"
     CDS             complement(15968..16837)
                     /locus_tag="ACG930_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0517960.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16907..18190)
                     /locus_tag="ACG930_000783"
     CDS             complement(16907..18190)
                     /locus_tag="ACG930_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0517961.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18204..19889)
                     /locus_tag="ACG930_000784"
     CDS             complement(18204..19889)
                     /locus_tag="ACG930_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFQ0517962.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20164..21189
                     /locus_tag="ACG930_000785"
     CDS             20164..21189
                     /locus_tag="ACG930_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0517963.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21784..25437)
                     /gene="rpoC"
                     /locus_tag="ACG930_000786"
     CDS             complement(21784..25437)
                     /gene="rpoC"
                     /locus_tag="ACG930_000786"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFQ0517964.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(25516..29133)
                     /gene="rpoB"
                     /locus_tag="ACG930_000787"
     CDS             complement(25516..29133)
                     /gene="rpoB"
                     /locus_tag="ACG930_000787"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFQ0517965.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29861..30829
                     /locus_tag="ACG930_000788"
     CDS             29861..30829
                     /locus_tag="ACG930_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0517966.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30847..31752
                     /locus_tag="ACG930_000789"
     CDS             30847..31752
                     /locus_tag="ACG930_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0517967.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVKSFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31749..32555
                     /locus_tag="ACG930_000790"
     CDS             31749..32555
                     /locus_tag="ACG930_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0517968.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32712..33680
                     /locus_tag="ACG930_000791"
     CDS             32712..33680
                     /locus_tag="ACG930_000791"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFQ0517969.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33997..34521)
                     /locus_tag="ACG930_000792"
     CDS             complement(33997..34521)
                     /locus_tag="ACG930_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFQ0517970.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34808..36448
                     /gene="scm"
                     /locus_tag="ACG930_000793"
     CDS             34808..36448
                     /gene="scm"
                     /locus_tag="ACG930_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFQ0517971.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTS
                     STTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSK
                     RALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(36603..37589)
                     /locus_tag="ACG930_000794"
     CDS             complement(36603..37589)
                     /locus_tag="ACG930_000794"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFQ0517972.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(37612..38178)
                     /locus_tag="ACG930_000795"
     CDS             complement(37612..38178)
                     /locus_tag="ACG930_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFQ0517973.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(38192..38608)
                     /locus_tag="ACG930_000796"
     CDS             complement(38192..38608)
                     /locus_tag="ACG930_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFQ0517974.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(39065..40999)
                     /locus_tag="ACG930_000797"
     CDS             complement(39065..40999)
                     /locus_tag="ACG930_000797"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0517975.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            41301..42236
                     /gene="pplA"
                     /locus_tag="ACG930_000798"
     CDS             41301..42236
                     /gene="pplA"
                     /locus_tag="ACG930_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFQ0517976.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            42326..43429
                     /locus_tag="ACG930_000799"
     CDS             42326..43429
                     /locus_tag="ACG930_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFQ0517977.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            43442..44395
                     /gene="menA"
                     /locus_tag="ACG930_000800"
     CDS             43442..44395
                     /gene="menA"
                     /locus_tag="ACG930_000800"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFQ0517978.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(45209..46555)
                     /gene="gor"
                     /locus_tag="ACG930_000801"
     CDS             complement(45209..46555)
                     /gene="gor"
                     /locus_tag="ACG930_000801"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFQ0517979.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(46689..47942)
                     /locus_tag="ACG930_000802"
     CDS             complement(46689..47942)
                     /locus_tag="ACG930_000802"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFQ0517980.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(47948..48871)
                     /locus_tag="ACG930_000803"
     CDS             complement(47948..48871)
                     /locus_tag="ACG930_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFQ0517981.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(49092..51584)
                     /locus_tag="ACG930_000804"
     CDS             complement(49092..51584)
                     /locus_tag="ACG930_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFQ0517982.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(51591..52058)
                     /locus_tag="ACG930_000805"
     CDS             complement(51591..52058)
                     /locus_tag="ACG930_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFQ0517983.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT        15079 a        11002 c         9513 g        16602 t
ORIGIN      
        1 aaaaatttgg gaacatttgc attttacttt tattgaagcc attttttctt ttcacaagaa
       61 gtttaacttt ttgaagttca tctagtgctg ataagattgt attttttgac attcccgaaa
      121 tttctacgag atttttgatt tcaaatatca aaaaaatttt ttgattctca tcatacaagt
      181 tatttttcaa tgaaagtcta tttctatctt ttagtaacat ataaactaac ttagaactta
      241 gtttcatttt cttatatttt tcatttacgt ttaaaaaaat aggatattga tagtataatt
      301 ctgcatatat atcagaatta gaatagcctt gcttttcaac taagctttca acttcttttt
      361 cattcattgt cacacctgct tctgatttta tttgctataa tagattcaaa taaagttttc
      421 tcagaacttt attattgagt gttcccccga tctgcaaact gacgggaaca ctctttttaa
      481 ttttttctac ttcatcaaat ttaaaaaacg aggtgttttt taaatttgat gactcaatat
      541 ccattttttg cattcttctt ttgaaaacaa ctccattttt tctaataaaa taactggcaa
      601 tcccattctt ttaaatttca aaaaagttgt atatgataca ttcaaatatt tagccatctc
      661 ttttcctttt agaaatggtc tttctaatcc ggtatcaatt cttgcttgat caatagcctc
      721 ttttgtcatt tcaaaaacat aatttttcaa ttgattcgtt tgttgtttat ctaacattac
      781 tgtaattcct gcatccatta tttttctcct ctcattttct atttcttcaa tcagccaact
      841 cgccaagttg tatttattta gattttcaaa tcattaagta accaatttac caacttttga
      901 taagtagatg ctctaatact ttctttgctc ccattttcga ttttgacata tgttttccga
      961 tttataccta tcaattttgc tgcatcgttt ttagtaagta taagatcggc tctatgtctt
     1021 cttaagcttc taatgaattg atcattaaga gttatcattc agcgcctcct ttcaaattat
     1081 tcactttgtg gtttttatct taataagcac attttaaacc acaaaacgag taatatcaat
     1141 taaaatatta ctcaatttgt ggttttcatg ctataatagt ttggaattta ctataggggg
     1201 cgttactttg aatagaataa aattttatat tgattccagt aaaaagacca ttaaacaaat
     1261 tagtacagaa actggtatta actatacaac tcttacgaac tattaccgtg gtgagcgaaa
     1321 tcctagaaat actgaaacat ggaatatcct tgctgattat ttccatgttc ctgtaagtta
     1381 tttgatggga ttagacgaaa caaattccat agaacaacct aatcttgata gaataaaaac
     1441 tgctcgttta gaaaaaaagg acaaaatagt caagaatatt gccagtcttg actcagatta
     1501 ttttactgaa ttatctaatc tatacttttc catgacttct ttacttgaag tcaaacttca
     1561 agaagatgac tccgactttc tttttttaaa aagtattcta gaggactcct ttgaatacac
     1621 gattctattt gccaaacaaa agaagtttat taataaagct ttaaacttaa atatcgatga
     1681 aagaaaagag ttagaatctg agttatttgg caacttaacc caagtacagg ttaacaatct
     1741 aaaaagagag ataacagctc gattaatatc aaaacttcaa taaaactaat tattcaatca
     1801 gccaactcgc caagttatca gattggagag attagttatg tcaatacaaa agtacacaac
     1861 aaaaagcggt gcacgatata gtgtccgctt gtatgttcgt aaagatgaaa atggaaagca
     1921 agaatactat gtaaaaaaag ggtttaaaac tgaaaaagaa gccaagttac acgaagcaag
     1981 aaaaaaggtc gagattgaag ataccggcta tcataagcct tctaatgact tgtttataac
     2041 agtgtatgaa gaatggttgc cttcttatag gaatcgtgta caagaaacga catatcaacg
     2101 tacaaaagac cttttccgct tgcatatact accaaaattc gggaataagt ccatttctaa
     2161 gattactcct gttcactgtc agaatgcagt caatgaatgg gctttaaaat tcaagaatat
     2221 caaacagctt aagtcttaca gctctcaaat atttgagtat gccatttttg cagagctatt
     2281 acaccgaaat cctatggcaa atacaaatct accaaagcgg gaaaagaaag aaaatgaaaa
     2341 ttacttttca ttagaagaac taaaagcttt ttgggatatt ctcaataaag aagagccttt
     2401 aaaacatatt ttaatcttcc agcttttgat tactactggt atacgtaaag gagagctagc
     2461 tgctcttcat tggtctgaca tttattttga agaacagcta atgtatgtta gaaagagcta
     2521 tgcaactatt cgaaatgaag agaagaatgc aagaagaaaa actgtcagga ttcaaaaaaa
     2581 tacaaaaaat atatcttccg aacgaatatt accaattgat gcacaaacta ttgaaatgtt
     2641 aaaaatctgg aaaaaagaac aagctcgaga gcttttgcag tttggcataa atacaaatac
     2701 aaaaaatcaa cttatcttta cctatgtaaa tgcagacggt gacattaatc aacctttgca
     2761 tgcggactat tcaaataata tattgaaacg tttagagaag aaatataaat ttaagcacgt
     2821 tactattcat ggattccggc acactcacgc tactcttcta ctagaaggtg gagcaagtat
     2881 caaagaaaca caagatcgat taggtcataa aaatgctgaa actaccctta acacttattc
     2941 tcatgttact gaaaaagctc aacgaaatgc gttagaaaaa ttcattgctt acactggttt
     3001 ataatattgt cattaccttt ctcattacca gaacgaaaaa aagacacctt ctcgcaatga
     3061 gaaagtgtct gaaatcgttg gtataacaac gattaacgtt ttgaaaactg tgaagcttta
     3121 cgtgctttct taagacctgg ttttttacgt tcgaccatac gtgcgtcacg agtaagtaag
     3181 ccagcacgtt taagagctaa acggaagtca ggatcaactt ctagcaatgc acgagcgata
     3241 ccatgacgga tagctcctga ttgtccagcg tatcctccgc cgtttacgtt aacaaatacg
     3301 tcatatgcgc cttttgtttc agtaacagcg aaaggttgat tgattacttc acgcaagtca
     3361 gcatgtggaa tgtattcttc aacatctttt ttatttacag taattttgcc agttcctggt
     3421 actagacgta cgcgagcaac tgcgttttta cgacggcctg tgccgatata ttgaacttgt
     3481 gccaatgaaa ttccctccta ttagattaag tttgtgatgt ctaaaacttc tggttgttgt
     3541 gctgcatgtg gatgttctgc tccaccgtat acgttcaatt ttgtaaattg tttgcggcct
     3601 aaagtgtttt taggaagcat accttttaca gaagtttcga tcaaacgacg agaattttta
     3661 gcacgcaatt cgccagcagt gattgatttc aatcctcctg ggtagttgct gtgacggtaa
     3721 taaattttgt cagtcgcttt tttacctgtt aatttcactt tgtctgcatt gatgacgatg
     3781 acgaaatcgc cagtatccaa atgaggtgtg aaagttggtt tatttttacc acgtagtaca
     3841 gatgcaacaa ctgttgaaag acgtcccaat ggaacatcag ttgcgtctac tacataccat
     3901 ttacgttcta cttcgcctgg tttggccata tatgttgtac gcacgttatt ttcctccaat
     3961 ttaagttctg atgtttgaca tacacttcga gtttccgggg ctctttgtgg ggcaaacaat
     4021 accatttaac atattacccg ctaatctagt caatgtcaac gtttttctgc ttgattgaaa
     4081 aatttatatg aaactttact tcttttcttt cttttatata aaagggtcgt ttcctgtcaa
     4141 aatgaaaaac aaaaagaggc tgtgacaaaa gtcttgtcac aaccccttat tttgaataaa
     4201 cggtgttctc ctgccaactc ctcggtcaca agtcacaata tccataaaac ataagaagct
     4261 gttttttaaa attgtttctt gtgactcgga gctgaacggc aggcttacaa cctcttggta
     4321 aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac
     4381 tattttgacg tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttttt
     4441 cggtcaagtt caacaacagt ttttacgcgt cgatctctgg cgctttgccc aaatgagctt
     4501 ggatcatcca gatacgtttt tctgtggctg ttttgaattc gataaagata tcttgtgttg
     4561 gatcgtcgcc ttcttctcca gaaacttcga ttcctttttg gtaaagatct gctagataac
     4621 gatagcctgc aacaagtgtt tccaaacgtt ctggaatagt acgatcccag cggccaattt
     4681 catcagggat ttttgtgtta tctgcaaatt cacgcaatgt agaataaggt gaaccgtcta
     4741 atgtgatcaa gcgttcggat acttcatcta actgagcgtt caaatcatcc atgaactcat
     4801 ccatcattgg gtgcaatgta aggaaacctg gtcctctcat gtaccaatgt gtttggtgaa
     4861 caacaacaga catttggctt agatctgcaa ctaattgatt taatacttct ttggtttgtt
     4921 ggaatttcat ctttcttgcc tcctaacatt ttcttacact taaaataata gtagactttc
     4981 aatgaaaagt acaacaaaat catttacctg agaacgattt tcagttcgct tttttatccg
     5041 taaagccaat catttttcag aatcagctaa ttcttctcgc agttgagcaa attgctgata
     5101 agtctgtgct aaatgctttt gtgtcgaaac aaataatgga tagattttct gatatttttt
     5161 atgatcagtt tcttgtactc caacttgctc tttcaattct atcaattcct gtgcttcact
     5221 gatactttgg atctttccga tgcttctcca gcctaaaatc acagctccta atgcggatgc
     5281 ttctgtgaca gtagggaaaa caagcgggta acccagtaca tcagccatca tctgacgaaa
     5341 aatcggagat tgagcaaacc cgcctgtagc acggatctct gtgagctgat tttcctggca
     5401 aactcctttt aaaatccgat aaaggttgag acagatccct tctagaatcg ccttcatcat
     5461 ttctttttct gtatgttgcc gctgtaaacc gataaaactg ccaaacgcat ctgcgtccca
     5521 aagcggtgct cgctcaccaa gtaaataggg atgaaaaatc agaccattgg cacccgctgg
     5581 cacaaaagcg atagccgaaa gcagtgcatc atatggattt tctccttttt ctttagcaga
     5641 ttgaacgact tcctgtaaaa atgtatgccc tgcccaatca aagatgccag caccattgct
     5701 agtcgctcct cccactaccc aatgtttctg atccagaaca taacaaaacg tctccatttc
     5761 tggatggaac tgaggctgag tagtaataaa acgaagtgct ccgctcgttc ctacggtcaa
     5821 agcggcgatc gtatcaccaa aagcacctaa ccctagatta gaaagcggcc cgtctgcccc
     5881 tcccaaaaca aatgatatat catttggcaa acctagttct gctgctgttt ttgatggtag
     5941 acctgttact tgataggtgg aaggaaagac ttgcggcaat tgctctattc gaatgttcaa
     6001 gtagtcaagc acttcttctg cccattggaa ttcatggata tcaaaatatc cagttcctga
     6061 agctgttccg tagtcgctga tcagttcgcc aaacaatcta taaaagatat agtctttgat
     6121 accgacaaaa taagcagttt ttttgaataa ttcaggttgg ctgttttgca gccacttgat
     6181 tttgttcaat ggtgtcattg gatgaatcgg cgtcccagtc tgccgataaa attctttgcc
     6241 aagcacggta tatttcagtt tttctgcttc gtccgctgct cggttatctg cccaagtgat
     6301 cattcgagat aacggtgttt tctcttcatc caacaatatc aggccatgca tcgcagagga
     6361 gaaggagaca aattgaatga ttgtgtctga aggcaactgt ttaattactt cttttataac
     6421 ggtgcagaca ccttgaaaga tcaattcctg atcttgttct gccatccctt gtgtttcttg
     6481 gatcaaaggg tagcgaaaat aagcggatgc tgcttcttgg gcttcatctg tgaaagcaac
     6541 tgctttggtt tgtgtggttc cgatatctaa tccgattgaa acgttcattt tttcacctca
     6601 aattttatgt atgtacaaaa atttagttta agcttgcgta tcttggtttt gaaaaggggg
     6661 agatggcgtg ttactttatt ttatcattgg ttgctgtatc ggatcatttt tatgtttaac
     6721 cgcccagcgg attccgttag gtcactctat tatttatcct agatctcatt gtgtcaaatg
     6781 ctgtcgttcg ctttcttggt atgaattgat tccgattctc tcgatcatcg tccaacgatt
     6841 tcgctgccgc tattgcaggt gtcggttgcc cttctactat ttgttggcag aagccttatg
     6901 tggtggtctt tttgcctggt tctttacttt ttcttccgca agaaattttt cgacgttcat
     6961 atggatgctt tcggctttgc tattttcgtt gatggattta ttttacttca tggtccattc
     7021 tcacacgcta ttctgttctt gggcaatttt atggattttt tggttgcagg ccggcgtctt
     7081 ccaatggcaa agtgtgctgt taacgtttat cgtaggcggt gtgtgccttc gctatggtca
     7141 atcctatctc ggagctggcg atactctgtt gatgctttct tggagtggtg gcttgtctct
     7201 agaagagttg cttcagatct tgtttcttgc tagtctgttt ggaatatccg ttttttctgt
     7261 ttactttatc tgtcataaaa aaaagttgga aaagctgcct ttcattcctt ttttgagcag
     7321 tgcgttgctg attgtccttc atcttaggta ttgaaaaaag gttgtgacaa acgacttgtc
     7381 acaacctctg atatatagtg ttctcttacc aaatccttgt gacttggagc taggcgacag
     7441 gttcacaacc tctccactaa atggtgttca atcagctgac cctcagtatt agctcaaaat
     7501 gctggtttta caacctctga tatacggtgt tccataagta gctttttcgg cttcttattt
     7561 cttgacgccc caatgtcgac gaaggaaacc tgcacgtcca gaaccttctc gataaagatt
     7621 gtaatggagc ttgtttttct tgtaataatc ctgatggtaa tcttctgcag gataaaattc
     7681 gcttcttggt tcgatttttg tcacgattgg cttatcgaat cgcccgctgt cttgcaatgc
     7741 ttgttttgaa cgctctgcaa tatttcgttc ttcttcatca ttatagtaga tcactggacg
     7801 ataagaatca ccgcgatcag cgaactgtcc taatgcgtca gtcggatcgg tttgctgcca
     7861 atagatttcc accaactgat cataagaaat aacttctgga tcatattcga tctctactgc
     7921 ttctgtatgc cctgttgtgc ctgttgttac ttgttcataa gttggatttg gtacatgccc
     7981 gccagtataa ccggatgtca cagaaatgat ccctggctgc tcttcaaatg gtttgaccat
     8041 acaccaaaag catccgcctg cgaaaactgc tttttttgtc atataaaatc cccctttttt
     8101 ctcatcatac cttgatttcc aaaaggagga taacgttttg cttgtgacag aaaaaacgga
     8161 aactattata tacgtgatac ggcttctgat aaatgccaaa acgaacgtac ttgatcaaaa
     8221 acggttaaat caggaatcac atattcagca gaaggaagat ttatgttttc acctattccc
     8281 aatacatgca tgttaccagc caaagctgct tgacaaccag cttctgaatc ttcaatgacc
     8341 aagcatgcat ttggcggtac attcaattgc tgtgctcctt tgagaaaaac ttctggatca
     8401 ggttttgctt ttgatacttg cgtgccgtca ataaggacat caaaataact tgtcaaattc
     8461 gttttttcta aaatgaggcg tgcatttttg cttgctgatc ccaatccgat cttgatgttt
     8521 gtttttttca agtactcaag aacagctatt gcaccaggca aaacggatgt ttcatccatt
     8581 ttttgaatcg cttgaagata tagattgttt ttttgctcag caaaggctga tttctctttt
     8641 tctgagaatt tctgttccat ttttccaaat gacagcaatc gctctagtga ctcggttctg
     8701 gatattcctt tcagttgctc gttttctttc tcagtgaatg gaatggacag ctggttagct
     8761 aaaaccagcc acgcttcgta atgataacga gctgtgtcta caagaacgcc atctaaatcg
     8821 aatagtgctg ctttgatttt catcgattac ctccttgaaa atgaacgact tgaagtaaag
     8881 atgcgatgtt tttagctgtg cgatgaagat tatcagtggc ttgctgtaaa gcttcttgta
     8941 aaggcacagc tgcaggaagg atcggaaaaa cggccgaaat gccaacatct gctgcttttt
     9001 cgcttccttt accaacactt ccgcaaatag ctatcacagg aacgccctct ggtactcttc
     9061 tagcaatccc aactggcgct tttcctttta gactttgtcc atctagacgt ccttcgccta
     9121 cgattacgag gtctgcttgc tgtacccgta tcgaactcca gtaaatccaa tacgtagtcg
     9181 atgccagaga ctattttccc tgaagcaaat gctaacagtc ctgcacccat tccaccacca
     9241 gcactactgc ccgatgcctc gattacttga ggggcaaatc tcatataaaa atcatgcatg
     9301 gcttggtcag ccactgctaa ttcattttct ttcaagcctt tttgtggtcc gaaaacaaaa
     9361 gaagcgcctt cttttccgca taaaagatta gtaacatcag taatgacagt gattttggct
     9421 ttaatcagct caataggcac gttcgtttta tcaactgtag caattttacc tagattttct
     9481 cccagtgctt ctactttttg attatcttga tcgtaaaaag cataacctag accttctgcc
     9541 atgccgatgc cgccatcgtt ggtactactt ccgccaacgc cgatgatgat gtgtcgaaca
     9601 ccttgttgca acaattgtcg tatcagttct cctactcctc gcgtggataa cctaagtggc
     9661 tgttgttggt ttagtgggac atctttcaat ccgacgattt ctgccatttc aaaaatcgca
     9721 gtttgaccgt ctgaagcgta ctggatttct ttgtttttgc caaatgcatt agtaacgact
     9781 gctgtttgcc gcttcaacct taaactgtct gctaatgatg aaaccgttcc ttctcctcca
     9841 tcgcctatag gtagcagatc atattcagcc tgaacaaaaa cttcttgaaa acctgattga
     9901 atggcttgtg ctgcctctaa ggctgtcaga ctttctttga aagaatctgg cgcaatcaga
     9961 atacgcatta ttttcccctc cgttccaaga tcagttcttt ttccagctgg tattggtctc
    10021 cattgacaaa aataggtaat gtttctttcg tctctttttt tattactatt tgtttttttg
    10081 tcaaaacaaa tagcaacctg tgatttttcc aaataaaagg aaaagaaatt ttttcccatg
    10141 ctgaaggaag tcttggagaa atagaaagag ttccattcgt tactgtaata cctgaaaaac
    10201 caaatataac tgctagccat agtgctccta atgaagcagc atgaattccg tcatctgatg
    10261 aatgcggatc tggtcctaaa tcaatcaggc acgcttcttg gaataaatga tacgcccatt
    10321 ccatttcttg gatacggcaa gcctctatgg cgtgaatcgc tttactcaac gatgagtcgt
    10381 ggattgtttt gttttcatag taatgcaaat tcttagaaac gattggttga gaaaaatact
    10441 caggtaataa gtataacagc atgacaagat ctgcttgctt gctgacttgg agttcattta
    10501 cttcgctacg ggcataatca agtaaaatag actggctgcc aggacgttct ttgtaagtgg
    10561 tcaaatcaat aactggctta ctgagatacg tgtcatcttg cggaatcagc tgttctttgt
    10621 taggcactgg caaatataac ttatctaaaa aattttgaca ttctttcaaa aaaagcggat
    10681 cgccagcttg atatttaaca gctaaggcca cattataatg cgccagatag ttcgtatatg
    10741 cattattgtc gatatattct gtgtattcat ctggaccaat gactctgtgt atctctaaat
    10801 gatcatcgac ttttacagct ctgctcagcc aaaaagctgc tgtttcatga atgagcgttt
    10861 ttccctttgt ttctaaaaac gattgatcct ctgttgcttg gacatactct tgaacggcat
    10921 aagcaaggtc tgcactgata tgatgttctg cggcagctga agcaacttct tgtcttgttc
    10981 cggttttgat attcaatgca gcaaatttgg gtgtctcttc ctgaccagtg tgtgcgcttt
    11041 cccatgggaa aagtgcacct tgatagtgat aatctcttgc tttttgccgt gcgccttcta
    11101 atcgatcata acggtacagc agcaaattct ttgctacttc aggaaactga tataaaaaga
    11161 aaggcaggat aaaaatttcc gtatcccaga aaacatgccc tttataacct tcgccagtta
    11221 gtcccttcgc ccctacacta acacttggat cattgcgggg agtcataatc tgtaaatggt
    11281 aagcagcgaa gtccatcgct aactgatcga aagaagaatc gccttggatc gttatccgat
    11341 gctgatgcca aaaatctgtc caataagaca tcgactgctc taaaatttct gtataactaa
    11401 cgcttttctg ggcttgggca atacttttct taaacgggtc tgtttgctga agagaggtag
    11461 agagcacgat gatcttctcc agcgtaaagg acgtattttt tctgatcttt tctgaaaagg
    11521 aagcggtgat ccggcgattt tttgcttgga atacacctgc tttattgaat ttagctgcaa
    11581 tcccaatatc aattttactt tctgttgtct ggtaggatgc actgatcaaa tcgtcaccaa
    11641 atactcgcag ttctttttca accaactgct gtgtaccaaa attggtttgc tgtccatcga
    11701 tacccgtttt cacatctact tggcagtctt cggtcaacgg cttgatgacc actttcaggg
    11761 ctgcctgatg gagattattt tgatcagcaa cacgacaagt aatgacttcc actttttttc
    11821 cttgagcagt ttcaatgagc gcatagcgtt taagctctcc catttctaaa tctagtgccc
    11881 gctcgtatgc aagaactttc atcgtctcaa gagaaaaatg ttcaccgtcg atttttattt
    11941 cccatctgat gacatctggg agattcacta actcggctga ttctgctcct aaaggtcggt
    12001 tatatacacc agctgcaaac attcccctta cttgattccg atagtcttcc tcctggcttc
    12061 ctctgatacc aaaaaatcca tttccaatgg tcatctgact cgcatactta ttgatatact
    12121 ctaaatcaaa ctgtttttct tctactttca taaggtaata acttctcctg tttctgccga
    12181 acgatataaa ttttccacca gattctggat gacatatcct tgccagccat ctgcaatcat
    12241 ctgagtctgg tcaccgagcg cccgattcac aaaatgagcc atacttagtt catgtgggtc
    12301 attaactggc gtggtctttt gtaaggaaac cagctttcca tctacatctt cgaatagttc
    12361 gcctggatac agattagcac ctgcctgatc gccacaaaaa gccacattca gtttgtcttc
    12421 tctgatattc aaagcaaacg aagtattcag ttggatgatc ttgccgtttt ctaattccag
    12481 tgtgccaaaa attgcatctt ctactgtgaa tttgcttgga tcccatttcc cgaatttccc
    12541 tgaatttttt ttcgtaccaa ttttttggaa gctgtacgcc cgaacgcttt ttactttagg
    12601 aaatccagta atatacatcg ctgtatcaag catgtgaatg ccataatcga tcaaaggccc
    12661 gcctccttga agttctttgt cgataaacgt tccccagcct ggaacaccag accgacgaag
    12721 cgcattcgct tctacgtaat aaatatcccc gagaacatca agatgattct tgatcattgt
    12781 tgcttcgtca gaaaaacgat gctggaatcc ataagccaaa atctgcccgt ttttatcggc
    12841 tgtctctgcc atctttcttg cttgatcagc tgtcatagct ggtggtttct cgcacatcac
    12901 tgaagcatta gcttcgaggg cagccaatac atgttcgaag tgaaagcgat tggctgtaca
    12961 gacactcacg atatcgggag aaatctcatt cagcatttgt gtaactgatg tatacgcatg
    13021 agaaaatcct gtacgtcggc aaaagtcttc tgctcgctgg ctgactggat caaccacagc
    13081 ggccaattct aagacatctg atcttttttg ataataagca gcatgtactt tttctgctac
    13141 ttgtccagcg cctatgattg ctactttctt catttatttc tctctccttt gcttatttac
    13201 ttattgttat tctttctcta ttctttctct aaatcattta aatgacgcgc tgtttccaga
    13261 cagtttttca agtattgcaa tgattcctga taaattttca cttcattttc tcctcgcaaa
    13321 cgacattcat ataccatata accttcatac tcattttgaa gtagcgtttg aaaatggcga
    13381 gtaaaatcaa ttgcgccaga tcctggttgg tagcgatgat tatctgctaa atggatatga
    13441 cccacatact ctttttgcgt agtcaatgct tttgaaatat catcttcttc aatattcata
    13501 tgataaaaat cagcgatgat ctgcacatgt ttcaattgat tagagtcaat gtaatgacgc
    13561 gcatccgcta acaaattgat catatggtct tggtatcggt tcaaaggctc caaataaata
    13621 accgtacctg tttcttcggc tactttatct aaataacgaa gtgattcgct gactgcttta
    13681 tagtctcctt ctttgcttcg gggtgaaacc atcggcggta atcgataagt gaacattccc
    13741 caagctgctg ggataacgat tcctttgcct ccaacctcgc ttagtgcacg caaaatctca
    13801 gcaatttgac gtacaccatt aagacgccgt tcttcgataa agtcaccgat ccacccatcg
    13861 tagccgttac aagctgtcac tactgggatc cctgtttctt tgattgcctg tttgactgtg
    13921 tcgatatttt ctattaacaa cttaccgtcg atttcgtatt cttcaaatcc acagtctttg
    13981 ataaatctaa atttttctaa aatgtctctt gggaaaaatg cttgatcttg cgtaccgaat
    14041 ttcattgttc tcctcctcgg acttgaacgc ccattttgat actttcttct gggtgctggt
    14101 ctacataacg catgtaagct tctgcgcttt ctgcaaatgg cacaactgga tcaatgattt
    14161 cttcacaatc caagtaaccg ttcatcaata attcccaaca tgtgtcctcg attcgtttac
    14221 ggttccatct tgggtaatct gggtttggtt cactagatgc tcgagcaaag acgatttttg
    14281 cattattgaa atgtgcttcg cgaccaagat taaacccagc tggaaaaggt ttagcaaagg
    14341 caacataaga aatgatcccg ccatagccga tccctcttaa agaagcttgt aatgcggcag
    14401 cactgccact cgtttcaata actgaatcta ctccacgttt atctgtcaat tcctttagac
    14461 gaaaaccgac atctgctttc ataggatcta gcgtgtaatc ggcaccgtat ttttctgcta
    14521 attctctacg ctgcgctatg ggatcgatcc caacgatggt agtagcacct gcttttttag
    14581 ctaattgaat cgcaatttgc ccgatagcgc ctaaaccgaa gattgctaca gcatcacctg
    14641 ctcgaacatg tgcttcccgg ataccaccta aagcgaattg agcaggatcg taacatactg
    14701 catttttcca ttgatccaac cgatcaagtt tacgtagttt ataattatca acaccgtttg
    14761 taatcagcgt ttcacgaatg ggtccataag tgcagactaa ctctcctttt tgatactctg
    14821 tcaccaaact gcccgtttct tcgatcgtac cgacaatcat atttcctaat tgaaattcgc
    14881 caaataccac accgcgttgg cttccttctt ctcttggcaa gaataggcgc cattcttctg
    14941 aaaattcttc atcgataaat ggacttaatc ctctaaagtc gacaatttct gttcctggtt
    15001 ttggagtagc gaaaattact cggatacgta cttcgttctt ttcgatctca cggtcttcgt
    15061 aatctttgaa tccggctatt cttggttcta atgcaactaa ttttttcatc ttttctttcc
    15121 tctttctttt ctttttatcc ttttacgccg ccttcgacta aatcaccttt aataaatcgt
    15181 tcagataacg catacataat gatgactggt aaagcggtca ccaatgaagc ggccatcatt
    15241 cgtccccaaa tgtagtctgg tgtactgaat aatgtgttca aaccgattgg taaagtaaat
    15301 ttttcggagg tcgacaggaa aatcgaagca aataaataat cattccacga aaccataaag
    15361 caataaacga agacagaaat gattccagaa atagccaatg gtataatgat ccgaataatg
    15421 atctggatcc ggctaagacc atcgatcatt gctgcttctt caatatcagt cggaatcgtg
    15481 tcaaaataac tttttagcat gaatatcgca gtaggaagtg tttgaacgac catcgtgata
    15541 atcagtgctg tattggtatc atacaaacct agaccggaaa tgattttaaa taatggaaca
    15601 acgatcaaaa taccggaaaa catataaacg gtgtaaaagc tagcattgat tttcgagcga
    15661 gctttgaagc gtagttttga caaagcgtat gccccgctga tcccaatcac tactgcagtt
    15721 acggaggcta tcaaggagat cactaaacta tttttgaaat acatgatgaa tggaaaaatc
    15781 tcagcattga aaatatcctg ataatgttca aaagtccatt ctttcggaaa aatagtttgt
    15841 gtcgttgcaa ttgcttcttg tgaatccttg aatgatgtca tcagcatgat caaaaatgga
    15901 aacaaattga cagctaatag caacaaaatc gtcgcgtaaa ataagatttt cctgctcttt
    15961 ttatttttca tttcaagtcc accttctttc gtgagagcaa gacgaccgct gcaataatga
    16021 tgaacaatag aatcgatata gctgctgctt ttccaagatc attgaacgca aaggctgtct
    16081 gatacaaata aacgcctaag atattgactt tattcgtcag tagatagaca tctgtaaaca
    16141 tatagaacat ccagatagat cgtaaaacaa tcacagttgc tagtactggt ttgattgccg
    16201 gcagtgtcac gatcttgaac ttctgccaag catttgcacc gtccatttca gctgcttcat
    16261 aaagcgtttt gtcgactgtt tgcaaaatag ccaaaaatga aataaacgca tacggatagt
    16321 atctccagat agcaaacaaa acgaccataa agaagctagc aactggctgg tcgaaccaca
    16381 gcggtgcttc gttgaaaagc tgcaacctat ctactaacag atcattgacg attccataac
    16441 tattattgaa catatatttc caagcaaaaa tcaaagaaat agatggcgta acataactta
    16501 ataaaatcag tgaacgcacc gttttcctaa atctgaactt gcggttaagc aaaatagcta
    16561 cggctaatcc taaagctgta ctgcctgcta caactaagaa tgtgtaagca actgttaaac
    16621 ctaaagaacg ataaaattca ctatcactta aaatttcaag ataattgctt aatccgataa
    16681 aaacggcgtc tgagttagga ttcagcggca tatcgaaaaa actgatctga atattggaaa
    16741 gcattggaat cagcactaaa acagctaata aaagcatgct tggtgctaaa agtcccatgg
    16801 ctaattttaa gtcagaatgt ttccttggac gattcattga aacctccccc tgataatctg
    16861 ccaatagcta tctacttttt tcgaacacca ttggcagaac ttcttgttat ttcgtatttt
    16921 tttgtgcgtc agctaaagct tgatcgacat cttcgtttcc gacagttact tggttcactg
    16981 cttttccgat cacacctgag cttgtgatat ctcccatttt cgtgaaattc ttttccccga
    17041 ctagtccaaa gacttgtact tcatcaaaag cactagcaat ctcagatggc agctcgccaa
    17101 aagacttgat gacttcattt tctttgtaac catccagttc gactacttgt ttattcactg
    17161 gttgagcacc accaggagac atcaagaccc acttttccat gtttttcggt tgagataaga
    17221 aagctgtgaa tgcttcagca gcctcttttt gtttctcgtc tagaccagaa gaaatcgtca
    17281 atccagatac tgtgccatag acagcttgat ctttttgtgt tgggatagca aaaccgatat
    17341 tttctgagtt ccccgcttca taaacagaag gcaaaatgta agttgaatag attgccattg
    17401 gtgctgttcc attcatgaaa gcatctttga tttctgtcac atcattagag cctggcatcg
    17461 tgtattggga taagttttga taaaacgaca atgcttctct catcttttcc gtatcgatcg
    17521 ttacctcgcc ttcatcatcc aaaacatttg ctccatttga caaagcaaat tgagagaacg
    17581 cttgctcact cattgttcct tcagcagtag gcatagcaat tccatattgt ttattctctt
    17641 tatctgtgaa atgttgagca atttttaaaa tatcatccca attttctggt tctgaaaaac
    17701 cagcttctga taatttttct ttgtcatacc aaataccttg aacccagccg ctaattggtg
    17761 cagcaatata gctttttcca tcttctgaac gaacaaggtt tttggctccg tcataataat
    17821 tatcttctcc agcttcctcg ataacgtttt ggactgccgt ctgatcaatc agttcatctt
    17881 tatccatcac tttagcaaaa tcctgactga cttccattac ttctggtaat ttaccggaac
    17941 gagctaacgt aacgattttt gtattgaacg ctgattcttc taccggcact tgcttgattt
    18001 tgatgtctgg attttctttt tcaaaatcag caaccagttc attgatcaca cttaatcgtt
    18061 cctgttcgac agaagagtgc atgaattgaa tcgttgtctg ttgtgattcg ttagagcttt
    18121 gactttcacc acaagcagta agaagaaatc cagtagctag cagacaggta gtaacaataa
    18181 tttttttcat ttttttccac ctcttatttt attattttca gccacatata ttcatacggc
    18241 tggaatatca actttcgttc ttgactgcaa tggataattt gtccagaaaa caggtctagg
    18301 taatctcctt ttggtaaaag ataacctgct gattgattgg aaaaattatg gataactaag
    18361 actttctctt ccttcgcttc gcgaataaaa ctgataaaag aatctgctga gtccagtaag
    18421 taaatcaaac tattcggatg gaaggctttt tctttttttc gaatagatag catctgggtc
    18481 aattcaccat atactgctgt tcttaatgga tctgtctgca actctttctc aatatctgct
    18541 aacaaaaatt tttgccgatt gatttttcga ttctctcctg ttttttctac gcctttgtaa
    18601 tcatttcgac ttcccagcac actttgaata taaattgccg gcacgcctgg taacgttacc
    18661 aaaaatgaat gagcagctaa aaagcgtttg cttctccatt ccgtcgtatc tgttggagaa
    18721 cttaacgcat ctagatacgt agcgtttatc tcatatggac tggtcgttcc atctgggttt
    18781 ttcttgtagt ttactcgggc accctctttc ttcagctgtt ccactaattc aaggatcgtt
    18841 ttttccggca gaatacctcg taccggattc aatccgatac cgtcatggga ggctaaaaaa
    18901 ttaaaaaaag ttgttttttt cgatgcgaaa tcgatggttt ttaaccattc tttcaactta
    18961 cttgtattac ccgaacgaat cgcttgaagg gtcaaaggtg gtagcgaaaa ctgatagacc
    19021 atctgtgctt cattctcgcc attcccaaaa taactgatat tatctttgtg tggcacattt
    19081 gtctcagtga tcaataccgt tcctggagct gcttcatcag cgattgcacg gaataattgg
    19141 atgattttat gcgtttctgg caggtgtata caagaagttc ctagttcttt ccataaaaat
    19201 cccacagcgt ccaagcgaat aaatgaagcg cctttttcta agtaaaacaa aagaatatcg
    19261 atcattttca ataaaacttc tggattttta aaattcaagt ctacttgatc ttcgctaaaa
    19321 gtcgtccata cgtgtttttc tttcccgttt ttgtcaatga acgttgtaag taacgggctg
    19381 gtccttggtc tagtcacgct gcttgtatct gtatccagtg gcaaatcaat aaaaaaatct
    19441 ttgtacgtat cattcaagtt taaatattcc tgaaaccaag tactttcggc agacatatga
    19501 ttgcagacaa agtcgaacat taaccgtgtt tcgcttctca tttcttctat atcttcccat
    19561 gtgcccaaac ggtcgttgat tgcctgataa tttacaacgg agaaaccatc atcagatgta
    19621 tatgggaaaa atggcaagaa atgtacaact ctaaatgtat ctgccaaata cttttgataa
    19681 aatttcttaa atgtacgcaa agttggttgc tgctcttcaa aaaattgatc cccataagta
    19741 atcaagaaaa tatcttcttc gtcccaatgc agtttgcctg cctggccttt cttctgctga
    19801 taaacactga ctttttgttc aatcatagag gcggttttct cagacaaatc tgagtcgcga
    19861 taaatcgctt gtaaaagttt tgtatacatc ggattcccct ttcttttttg ggagcgttcc
    19921 caacgatttg atcatattat ggaaaacgct tactgtcaat agcatttttt taaataattt
    19981 tgatatacac aaaaatacaa ataagaaagc ttatgtatca ataattaata gcttcttaaa
    20041 aaaatatggt ctctcatgat catgcaagct attcctaaat tttcaaaatc atagacaaaa
    20101 aagaatgtct attgtactat ggaattattc taaaacgctc ccaaaaagga ggtgcatata
    20161 aaattgaaac ctactattta tgacattgcg aaaaaagcta atgtctcaaa atcaactgtc
    20221 tccagagtat taaataacca gccaaatatc tctgataaag caaaagcaag tgtacttcaa
    20281 gcaatcaaag aattgaatta tgaaccgagc aaaattgcaa gaggactgtc aggaaatggt
    20341 tttgacgcga ttctagcatt atctcatcgt acttctcata cgacctatgg caatcctttt
    20401 ttttcagatg ttattcaatc catttctgcc gtttctgaac aaaataactt cgacttgatt
    20461 ctacaaacgg caaaaacacc agaagaagag ctagaaaaat gcgcgaaaaa gatccaagaa
    20521 aaaatgatcc gaggaattat tattttaagc tctacgatgg atgaaacact tctttttgaa
    20581 ttggatcaat acaatattcc tattgtggta atcggaaaag tcggaaacga ctacacgaac
    20641 atctactcag tggacacgga taatttccag gatagttacg atttggtgga aacactgatc
    20701 aagaatggac accgtcatat cggctgtctc catgctccga cagaagttta tgtatccaat
    20761 gatcgtctca atggttaccg tcaatgctta tttgatcacc acctagatat ccgtaatgaa
    20821 tggattatag acggcggctt tcgcttagaa gatagcatgg cagcaatgaa tgatttaatg
    20881 aagctacgag aaagaccaac tgcgattttt tctaccgatg cattaaaatc attgagtatt
    20941 tacaaagtgg cagaacaatc tggaaagcag atacctgatg atctttcgat cgcaggattc
    21001 agtgatccct tattgtcctc cctattttcg ccacagttga ctcggataga cattccgaca
    21061 aatcagttag gaatcaaagc cacagaactt ttattccaac taatccacca ccaataccct
    21121 gaagaaaaaa gaatcattct ttcaaccgag attactctca cagattcgat ccaacaacaa
    21181 gaaatgtaga acagaattat aaaagaacag aaacactgag gataagtcag ttactctgtt
    21241 cttttttcaa tcactcatcc ctcgttaccc cctcccggta ttttagcgaa tttttcttat
    21301 tttccatctg ttttagatag ctgtggataa ctataatgtt tgtgttaaac tattttttcc
    21361 acagggaaga aaaaactatt tttaaccacg ttgtgtataa gtttttatag ttcgtttttt
    21421 taaacacatt tacccttatt tcaatccatg ttatttgggg atacttatct ctaaaacata
    21481 aatagaataa cagacatgtc tactggtttt gttttattcg aggaattatt caataatagc
    21541 tagcaaaata ttaaaaataa ccgctctatc ttcccatcaa tttattttgc attcaaaaaa
    21601 tgatctatct ttacttttgt tgattgactt ctcttggaag atgatcgttc cgatacctta
    21661 attggatacg aaccgatgtt gttaagatcc tttcccactt ttcttctagt tagacaaatt
    21721 attttagaca aaccaaaaaa gaggttgtga caataatttg tcacaacctc ttttttaaaa
    21781 tatctatttt gtttgattgt tcattgcgtc ttctgcagcc atttgcgctt caatatctga
    21841 aatactgtag acattttcgc ttgctacacc gacttctttt ggttccatgt cacgataacg
    21901 ttgcatacca gtaccagctg ggatgatctt acctataata acattttctt tcaaaccaag
    21961 aagaggatct ttcttaccgc ggatcgcagc atccgtcaag acacgagttg tttcttggaa
    22021 tgatgcagca gataagaaac tatttgtttc taatgatgct tttgtgatac ctagtaagac
    22081 aggtcgagaa gttgcaggaa cgcctcctga gactagcgta ttgtagtttt gatctttaaa
    22141 gtctgcgatg tctaataatg tacctggtaa gatatctgta tcacctggat ccattacacg
    22201 aactttacgc agcatttgac gaaccattac ttcgatatgc ttgtcgccga tttctacccc
    22261 ttgcatacgg taaacacgtt gtacttcacg aagcaagtag ttttcaacag ataatacatc
    22321 gcgaacttgc aacaattgtt ttggatcgat tgatccttct gtcaatggtg caccacggtg
    22381 gatcatatcg ccttctgcta ctttcatacg tgctgtataa ggaacagtat acgtacgtgt
    22441 atctgttttt cctttgattg ttacttcttt ggtacgtgtt gcaggatctt ctgagatatc
    22501 gatgacatcc cctgttactt ctgtgatcac tgcttgccct ttcggattac gtgcttcaaa
    22561 gatttcttgg acacgaggaa gaccttgagt gatatcgtct ccggcaaccc cacctgtatg
    22621 gaatgtacgc atcgtcaact gagtaccagg ttcaccgatt gattgagcgg cgatcgtacc
    22681 aactgcttct ccgacttcaa cgtcagagcc agttgcaagg ttgcgtccgt aacaatgttt
    22741 gcagacacca tgttttgtat tacatgtgaa gacagaacgg attgtcactg tttcgacacc
    22801 tgcatcaacg atttgttttg cgatgtcttc ggaaatcaat tggtttcctg caatgatcaa
    22861 ttcatttgtt tcaggatgac gtacttcttt acgggtgtaa cgtcccacta aacgatcttc
    22921 taatgattcg atgatttcat ttccctcgcg gatggcttgg atttcaagac ctcggtcagt
    22981 accgcaatct tcttcacgga tgattacatc ttgggccacg tcaaccagac gacgagtcaa
    23041 gtaacctgaa tcggcagtct tcaaggctgt atcggtcatc cctttacgag ccccgtgagt
    23101 tgagataaac atttccaaga cggatagtcc ttcacggaag ttcgaaatga ttggcaattc
    23161 catgattcga ccattaggag cggccatcaa accacgcatt ccggcaagct gtgtaaagtt
    23221 ggaaatgtta ccacgagctc cagaatcaga catcatgaag attggatttt tcgcttccaa
    23281 accttccatc agtttttgtt ggatgctgtc ttttgcagca ttccaaacag caatgacacg
    23341 ttcataacgt tcgtcatctg tgatcagacc acgacggaat tgttttgtaa tagtttcaac
    23401 ttgtttatgg gcattttcaa tgatttcttg tttttcattc agtacactga tgtcagcgat
    23461 ccctactgtg ataccggcat gtgtcgaatg tttgtaccct aagtctttca tacggtcaag
    23521 catcttagaa gtttctttta ctttgaatcg tttgaagact tctgcgatga tgtttcctaa
    23581 gtttttcttc ttgaacggta atactaattc ttgctctttg atatgtgcag gaatatcagt
    23641 accagcttca acaaagtatt tgtccggtgt ttggacggtc aagttgaagt ctgttggttc
    23701 attcagataa gggaattcag gaggcatgat ctcgttgaag atgatcttac caactgttgt
    23761 gatcatcgta cgttcttttt gccattcagt aaatggtttt tcacctaatg agttagggtt
    23821 cacaccgata cgtgaatgta aatgaacata tccgttgcgc catgcgataa cggcttcgtt
    23881 ttgatctctg aagaccattc cttcgccttc gcgtccttct tcttccattg tcaagtagta
    23941 gttacctaga accatatctt gagaaggagt aacaactggt ttaccatctt tagggttcaa
    24001 gatgttttga gcagctaaca tcaacatacg tgcttctgct tgtgcttctt cattcaatgg
    24061 aacgtggaca gccatttggt ctccatcgaa atcggcatta taagcttcac atacaagtgg
    24121 atgcaaacgg attgcgcgtc cttgtactaa aactggttcg aatgcttgga taccaagtcg
    24181 gtgaagcgta ggtgcccggt tcagcaatac tgggtgttcc ttgattacgt cttctaaaac
    24241 atcccatact tcgtcttctt gacgttcgat tttacgtttc gcatttttga tgtttgaagc
    24301 tagttcgcgt tgaacaagct cacgcatcac gaatggtttg aataattcaa tggccatttc
    24361 ttttggaagt ccacattggt acatcttcaa gaaaggtcca acaacgataa cggaacgacc
    24421 tgagtagtcg acacgtttac ctagcaagtt ttgacggaaa cgaccttgtt tccctttcaa
    24481 catatgagaa agagatttca atgggcggtt acctggtcca gtaactggac gtccgcgacg
    24541 accgttatcg atcaatgcat ctactgcttc ttgcagcata cgtttttcat tttgaacgat
    24601 gattccaggt gcattcaagt ctaacaaacg tttcaaacgg ttattacggt tgattacacg
    24661 acggtaaaga tcattcaagt cacttgttgc aaaacgtcca ccttctaatt gaaccattgg
    24721 gcgtaaatct ggtggaataa cagggataac gtccataacc atccagcttg gttgatttcc
    24781 tgaagcgcgg aatgcttcta aaatatccaa acggcggatt gcacgtgtac gtttttgtcc
    24841 ttgtgcagat ttcaattctt ctttcaattc ggctgcttct gcatctagat caacattatc
    24901 aagtaattgt ttaatcgctt ctgcacccat agcagcttgg aattcttgtc catattgttc
    24961 acgtttttcg cgatattcgc gttctgtcaa caattgtttt ttctctaaat tcgtatttcc
    25021 tggttcgatg actacatatg aagcaaaata aatgatttct tccaaagcgc gtgggctcat
    25081 gtctaataca agacccatac gtgaaggaat ccctttaaag taccagatat gtgaaacagg
    25141 agctgctaat tcaatatgtc ccatgcgttc acggcgaact ttcgaacgag taacttccac
    25201 tccgcatcga tcacaaacga ttcctttata acggatacgt ttgtattttc cgcaggcaca
    25261 ttcccagtct tttgtaggac caaaaatccg ctcacagaac aacccttcgc gttcaggttt
    25321 taaggtacga tagttaatcg tctcaggttt ttttacttca ccgtaagacc agcttctgat
    25381 tttttcggga gaagccaaac ctatttgcat actttcgaat ttatttacat cgatcaaaag
    25441 gggttccctc catttcattt aatggcaaac cgcaagacgg ctgatcttcg accgccttgc
    25501 agctcataga ccggattagt ctaaattatc ttctgcggtt tcaaagtttt ggatgacatc
    25561 gtctttttca tcttccactt gttcagcagc tttcttttct aattctttgg cagtttgctg
    25621 ttcggcaaat tttgtcaaag catcaacagt gatcaaatcg tcgtcttcat cgtccatgtc
    25681 gcgaagttcg atctctgttt cttcgatatc caagacacgc atgtccagac ctagtgattg
    25741 caattctttc accaatacgc ggaatgattc cggtacacct ggttttggaa ttggttcacc
    25801 cttgacgatt gcttcgtatg ttttcacacg tccgactacg tcatctgatt tgtatgtcaa
    25861 gatttcttgt aaagtataag ccgcaccgta agcttccagt gcccatactt ccatttcacc
    25921 aaaacgttgt ccaccaaatt gagctttacc tcccaatggt tgttgtgtaa ccaatgagta
    25981 aggtccgatt gaacgtgcat gcaatttgtc atcgaccatg tgagcaagtt tgatcatgta
    26041 catcacaccg acagacacac gtccatcaaa tggttcacct gtacgtccgt cgtacagaac
    26101 agttttcgca tcgctggcca taccggcttc acgaactgtt tcccatacgt cttcatcact
    26161 tgcaccatca aatactggcg ttgctacgtg gatacctaac tgacgtgcag ccatacccaa
    26221 gtgtaattcc aatacttgcc cgatgttcat acgtgaaggc acccctaaag gattcagcat
    26281 gatatcgatt ggtgttccat caggtaggaa tggcatatct tcttccggca taatacggga
    26341 tacaacccct ttatttccgt gacgaccggc cattttatcc ccttcatgga ttttacgttt
    26401 ttgaacgata taaacacgaa ctaacatgtt tacgcctggt gacaattcat ctccagcttc
    26461 acgagtaaag attttcacat cgtgaacgat accgccgccg ccatgtggta cacgtaatga
    26521 tgtatcgcgg acttcacgag ctttttcgcc aaagatcgca tgcaatagac gttcttctgc
    26581 agataattct gttacccctt ttggcgtgac tttccctaca agcaaatcgc catcttggac
    26641 ttctgcacca atacggatga tacccatttc gtctaaatct tttaatgcgt cttccccgac
    26701 attagggatt tcgcgtgtga tttcttcagg tcctaatttt gtatcgcggg cttctgattc
    26761 atattcttca atatggatag aagtgtatac gtcatctttt accaaacgac ggctcatgat
    26821 gatcgcatct tcatagttgt acccttccca agtcatgaaa ccaactaaaa cgttttggcc
    26881 tagagccatt tcgccttgtt ccatagatgg tccgtctgcc agagtatccc ctttttcgac
    26941 tttctcaccc aaatgaacga ttggacgttg gttgtagctt gttccggagt ttgaacgacg
    27001 gaattttgtt acatcgtatt tatctaatgc accgttgtcg cggcgtacgc ggatttcaga
    27061 agcatcaacg tattcaacga caccatcatg tttacataac aaagcagctc ctgagtcatg
    27121 cgctgatttg tattccatac cagtaccaac ccatggtgct tgaggattga tcaacggcac
    27181 tgcttgacgc tgcatgttgg cacccatcaa ggcacggttg gagtcatcgt tttccaagaa
    27241 aggaatacat gctgtcgcaa cggcaactac ttgtttaggt gatacgtcca tgtagtctac
    27301 tttatcaata gatacttcta agttttcact ttgagcacga gccataacaa cgtcttgagc
    27361 aaatgttcca tcttcattca atgggctgtt tgcttgggct acgatgtaat ggtcttcgat
    27421 atcagctgtc aagtagtcga tttggtcagt aacacgacct gtttcacggt ctacacgacg
    27481 ataaggtgtt tcgataaatc cgaatttatt tactttcgca taactggaca aactattgat
    27541 caacccgatg tttgggcctt caggagtttc gatcggacac atacggccat agtgggagta
    27601 gtgaacgtca cgaacttcat aaccggcgcg gtcacgagtc aatccgccag gtcctaaggc
    27661 gaaaagacga cgtttgtgtg tcaattcgcc aagagggttt gtttgatcca tgaactgtga
    27721 caactgagaa gaaccaaaga attctttgat acttgccaca actggacgga tattgatcaa
    27781 ttgttgaggt gtcaatgttt cagtatcttg gatcgacatt ctttcacgaa ccacacgttc
    27841 catacgtgct agcccgatac ggaattggtt ttgtaaaagt tcaccgactg aacggatacg
    27901 acgatttcct aagtggtcga tatcatcgac attgccgata ccttccatca agttcaagaa
    27961 atagctcatt gaagcaatga tgtcggctgg acgaaccgtt tttacagctg cttctggata
    28021 gccgtttccg atcacgttta cttcacgttc agggtctctt ggtgaaaata ctttgatgac
    28081 ttggacagtc attggatctg tgaccacacc gtcttctgat ggatagtaag tcactgaatt
    28141 taggccatta tcaatgaaag gagctagtgt ttccatgact tggtgagtca gaactgttcc
    28201 tttttcaacg atgatctcgc ctgtttctgg atcaactaat gtttcagcta atgtcagatt
    28261 caatagacgt gttttcaaat ctaatttttt gtttactttg taacgaccaa cgtttgctaa
    28321 gtcgtaacgt tttggatcga agaaacgagc attcagcaag ttacgtgagc tgtctgctgt
    28381 ttttggttcg cctggacgca aacgttcgta aacgtctttc aaaccttctt ctgttcttga
    28441 gtcgcttgcg tttttatgca agtctttttc gactgtattg cgtaatgttt cgctgtcgcc
    28501 gaagatttca aagatcgtat catcggaacc aaatcctaac gcacgaacta atacggttaa
    28561 aggaatctta cgtgtacggt cgatacgtac ataagagatg tcttttgcat cagtttccat
    28621 ttctagccaa gctccacggt tagggataac agtagaaccg aatccttctt ttccgttttt
    28681 gtcgactttt ccatggaaat agacacctgg tgaacggact aactgagaaa cgattactcg
    28741 ctctgccccg ttgatgatga atgttccttg ttctgtcatt aatgggaaat caccgaagaa
    28801 tacttcttgt gctttgattt cgccagtctc gcggtttgtc aaacgcaatg ttacatgtaa
    28861 tggtgcagag tagtttgcat catgcgcacg agcttctgct actgtatact ttggttcttt
    28921 caattcataa tctacaaatt ccaaagatag attgccattg aagtcatcga ttggcaaaat
    28981 gtcttcaaac atttctctaa gtccctcatc taagaaccat tggtaagagt ctgtttgaat
    29041 ttcgatcaaa tttggtaatt ccaacacttc actgattctt gcgaaacttc tacgttcgcg
    29101 atgttttccg tattttacta cgtgtccagc caagctcttc acccctctaa aatgtcattc
    29161 aaaaagacta cccgatcaat tgttacaata atatttcaaa tattattttt aggtaacaac
    29221 agacattttt tgcggctttt aggcaaaaaa aaaccaaaaa tagaacattc tcttgaaacc
    29281 ttacttcgtg agcttctact tttgtttcct tatattaaag ccgaaacgga caatatttcg
    29341 tttctgcctt ttcttcatca gatagttttt gcaacttcat atactacact tattttctat
    29401 aaaagtcaac acttcctggc gtttcttctg ctttttcgca acattttctt aatgttttca
    29461 attttatgtt ttcaattatc tgacaattct taattgacag acctttttat ctcggttata
    29521 ctttagaaaa ttcattttgt ggaggaactt ctatgcgaac caacatcaac caaatcgcac
    29581 caacacaact gaataacttt tactttagct actttagata ggtttgtatt catcatgatg
    29641 gatacaaacg ttaaacgaca gtttgtatct atgatggcta aagaactttg tattgcagca
    29701 aaaagccacg tagacaaaat gctaagtggc tgagcagtga aaatacaaag taaaagtatc
    29761 aagcattcta ctttttcaat ttattttccg acttttcaat ccatttggac attttgtctg
    29821 aatggatttt ttgtttccca aaattaagga ggaaaaagaa atgaaaaaaa atataatcat
    29881 cggattaggc gctgccctgc tactagcttt aggaggttgc gcacaaaaag acaattccgc
    29941 agaggcatca gatggacaaa aaacaattgg cgtattgcaa cttgtacaac ataactcgtt
    30001 agatgctgcc tataaaggat tcaaagaagg attagcagaa gaagggtata aagaaggcga
    30061 taatctaaca atcgattatc aaaatgccca aaacaatcaa gacaacctga aaagtatgag
    30121 tgagaaactc gtcaaagaag atcctgattt gctacttgga atcgccactc cagcagcaca
    30181 atctttatta aatgaaacaa ccactatccc gatgactgtc acagcggtca cagacttgga
    30241 acaagcccat ttagtcacat ccaatgaaaa acctggcggc aatgtgactg gcacgacaga
    30301 tatggtgcca atcgaaaaac aaatcggctt actgttaaat atcgtgccag acgccaaaac
    30361 aatcggcatc atgtataaca acggtgaagc aaactctaag atccaagctg atttggcaga
    30421 aaaagaattg aaaaaagcgg gcgtcaaagt caaagtactg acagcaaatt ccacaaatga
    30481 tgtccaacaa gtgacgaaaa gtctagctaa agatgtagat ggaatctata ttcctactga
    30541 taacacgttc gcaagtgcgg caagtgttgt cggtgaagtc gcaaaagaaa caaaaacacc
    30601 tgtcgttgct ggcgcagttg atcaagtcaa agacggcggt ctagcaacag taggaatcga
    30661 ctacgaaagc ttgggcaaac aaacagggat catggcagca aaaatcttag acggcaagaa
    30721 tccaagtgaa cttcctgtcg aaacagcgaa tgatttggaa ctgtatgtca ataaagacat
    30781 ggccaaagca ttaggcatca atccagacag catcaaagaa gctgaataaa acacaggagg
    30841 attctcatga caaatttgct ctctcttttc ttatcatctg catcgcaagg ggtcttatgg
    30901 gccctacttg cgattggtgt atacgtcact ttccgtatct tggacattgc cgacttgact
    30961 gctgaaggaa gctttccttt aggtgcaggg atcgcggcag taagtattac aaatggctat
    31021 catccattga cagcttgtct tctaggcttt ttagggagtg cggcagcagg gcttgtttcc
    31081 ggactgcttc acacaaaatt gaaaattccc gcccttcttg cagggatcat caccatgact
    31141 ggtttatatt ctgtcacatc ccgtgtgatg ggtgcgccga acatctcttt attgggtcag
    31201 ccaacgatct ttcattgggt caagtcattc ggcataacaa aagacaacgc tgtactgatc
    31261 gtcggtctgc tttttgcttt gatcgttgta tgtttacttg ttttgttctt acgtacagaa
    31321 acaggacttg ctattcgtgc aactggcgat aatctggcaa tgagcgaagc aaacgggatc
    31381 aacacagata atatgaagat catcggttat atgatttcta atggatgcat tgctctttct
    31441 ggctccttgc ttgcgcaaaa caacggcttt gctgatttaa attctggtat tggaacgatc
    31501 gtaattggac ttgcttctat tatcatcgca gaagttttgt tacgtaacca gccactattt
    31561 ctccgtctct tgactgtcgt tttaggtgcg gtcatttatc gttttatttt agcgttagtc
    31621 ttcgaactga atgttgaacc aagtgattcg aaacttgctt ctgctttcgt gctagtgatc
    31681 tgtctttctt tcccgcagat ccagcaaaaa ttccatttac ctcaaaaaaa gaaaggcggt
    31741 agtgtcaaat gaatgacgtc ttaacattgg aaaatctcca tcataccttt gaaaaaggaa
    31801 cgatcaacga aaatcatgtc ctgaaaggca ttaatctttc cttagatccc ggcgacttcg
    31861 tgacgatcat cggtggaaat ggggctggta aatctacttt gctgaacagc atcgccggta
    31921 cattttctgt cgatcagggt caaattttat tgaatggaaa aaatatcacg aaaaaatctg
    31981 ttgtcgaacg ttcgaaatcc atcagtcgcg tattccaaga tcctaaacta gggacagccg
    32041 ttcgtttaac ggtagaagaa aatcttgctc ttgctatgaa acgaggaaaa aaacgcggct
    32101 tcttccgtgg tgtcaaacca caagaccgaa catttttcaa agaccagctg gttcggctaa
    32161 atttggggtt ggaaaatcgt ttatcctcag aaatcggttt gctgtctgga ggacaacgtc
    32221 aagctattac gttattgatg gccacattac agcgtccaga actgatctta ttagatgaac
    32281 acactgcagc gcttgaccct gctacttcca aaacggtgat ggaattgaca gaaaagctga
    32341 tcactgagca gaatctcact gcttttatgg tcactcatga catggaagac gcgatccgct
    32401 atgggagtcg actgatcatg ctgcatcaag gaaggatcgt cgtagatatc cagcaagagg
    32461 aaaaacagca gctcacagtg ccccaattat tagcgttgtt caaacaaaac agcggcacgg
    32521 cattaaaaga cgatcaagta cttttatctt cataatcaga aagaggatgg gacaaaaaat
    32581 gaacgcccac cctcttcttt tttctctttc cttctttcgt ttttgcttta tgtatcaacc
    32641 gttgtttctt cgaaaactat tttgttctct ccttcttcct gatagaatgg atgggaaagg
    32701 agcttgatgc catgacaacg aaagacaagg tacttcaatt attgaaaaag acaccagatt
    32761 ttctttccgg agaaaagttg gcacagcaac tggaagtttc ccggacaagt atttggaaag
    32821 ccatcaaaga attggaaaag gcaggctatc gttttgagca cgggcctaca gggtatcgtt
    32881 acctgccctc tgacgtacta gatgcaaaag aaatccagca agagctacgg tcgtttattc
    32941 ctgatttgaa agtacaaacg atgatgactt ctgaatctac gatgaaagat gccaaactgg
    33001 cagcagctca aggagattct gtttcgaagt tatttgttgc tgatacacaa gaacaagctc
    33061 gtggacgttt tggacggcct tttttcgctg aacctggacg aggaatctac atgagtctct
    33121 tgctccatcc agacaaacgg tttgatgaat tgcctcaata tacgatcatc gcagccagtg
    33181 cctgtgtgaa agccattgaa tctgtaaccg gtcgttctgc ttcgatcaaa tgggtcaatg
    33241 atatctacat ggatggaaaa aaagtctgtg ggattttatc tgaagcagtc agtgatatgg
    33301 aaagcggcag gatcagtcat atcatcattg ggatcgggct taatttttct gttcctcaaa
    33361 atcattttcc agctgatctc caagaaaaag ccatctctgt ctttcccgac ggacaagcta
    33421 gtgtcacaag gaatcagcta atcagcaaaa tctggcaaga attgttcact tatctttctc
    33481 acccagaaaa agcgttggac ttctataaag aaaaatcatt cgtattggga aaaaccgtgt
    33541 cgttcaatca aaaaggaacg acttatgtcg gtcttgcaaa agaaatcggt gatcatggcg
    33601 aactgatcgt ccaaacaaat gaacagaaga tgagtttgtc ttctggcgaa atcagtctca
    33661 catctatccg tacgcaataa ttatcagatt tcacaaaagg acacctgatc tcatacagtg
    33721 tccttttttc tgaattctct tcaaaagact ctccttattc tatcagctga cagtttctct
    33781 atcctctaga aaaaggtatt ctaaaaatat ctataaagca tggtacactt tctttaaatg
    33841 aatcaatgca aaaaacaaga gagtcatcag tttacacgat caaaagagat agcaggccgc
    33901 ttcctttttc aatcttatag atagaccatg ggtaacgata aaaacaaaaa agaacttgcg
    33961 acttattttg ccgtaagttc ttttttagct agtgccttaa tctcttaatc ccaacaaacg
    34021 tctcgcatag atcacctgac cagagtgcat agcagcatca tcaataatag aaacgagacg
    34081 cattcctcgt gtgactggtg gtgtccagtt ctcgtcaatt acttcatcta gctcggaagg
    34141 ttccagcctt cttaagtaag aaatagcaaa atcagcagct cctcgcaagt atcctagcag
    34201 atcttctatt tgattagctt ggatctgctt tgcttgttcc agactatgct tccaatcttg
    34261 ttcgttatct gctatcgtca tcggaaaccg gctttcccag tcttgactat gccaaattgg
    34321 agaagttcct gctaaatcag caatctggaa atctaattct cgagcggtat gccaagccag
    34381 ccaagtcatt gatttgatct gcggggctct atcttccact ggaaaacgat tggcctcctc
    34441 aatagagacg ccttcaaaca aacgttcaaa ccgatcgtat gcccgatcca cactctcgca
    34501 tagcatatct aaataatcca tttattttcc tcctttttat ttatcctact tactttttcc
    34561 taattctagg atacctactt atatgttact acacaccctt attttttaca ctttaacagt
    34621 caccatcatc aatagtttgg agattgaaag aaaaagatag tgtcgaacta tcaattgaac
    34681 aagaagcaac aatatgaacg tttcattaat attctttaaa taaacaatga tttttcaaac
    34741 gaacagttta agactaggag aaaaagagta taataggaaa atgtttgaaa ggaaaggaag
    34801 gggaaaaatg aaaaaaaggg caagtttact agtcctagtt gctttgttgt tcaatatctt
    34861 ttcgtatggt gtggccgttt cagcggaaac atacattcct aaagaccctg ggaatattta
    34921 taatgatcta actggtaact atggcttgtt aggaattgct agtcaattcc acgtatttgc
    34981 taaaaataag acaactgtga atgcacatac agacggaaat atagcaacac atgaacttga
    35041 tgcaaaaaat aattttggta cagagcttca tgaaggttta ttgaaccaag aaataaatta
    35101 tatacaaaaa actgattctt tcgctaattc ttcaggcata cctacaggta gcacaagaat
    35161 gaataaattt gtcgttggca gtaacgtgga tgtagcactt caagatggtc atcctacagt
    35221 caatggatcc aggcttgatc acttaactcc agatgatttt tataaagatc gtgctgggca
    35281 tgaatatatt gatttcgagc aggaatttgc taaattgaat gtagcagcaa atgatcttgc
    35341 aacgatcact ccagctaaaa catatactgc tgcagatttt ccagacatga acaatcggac
    35401 aatcgattta actgatttat cagataccgg gtttttattg gtaaatatcg atgcagaagt
    35461 gttaacgatg aatacgccac ttcaaatcat taatccaaat gatcaagtag ttgtatttaa
    35521 tgtcatcaac agttcttctg cattgaacgt acagtcacca atcaaataca atgatcgttc
    35581 aaatcatgaa acagaagatt tttcggatgc gaatatctct tggaattttg gaaatgagat
    35641 gactgatttg acaatcagtg ctccttttca aggaacaatc cttgcgccta atgctactat
    35701 ccgcattact caaaaccaag acggaacgat tataggaaca aatgtgattt tagatgcagc
    35761 taccaatcgt tgggatccta acgaaatatt tatcagcgac aatggtacag atacgacaga
    35821 cacaagcgac agtacagata catctaccac aagtgatagc tcagattcat caacttcaag
    35881 cgacagtaca gatactacct ctaccacaag tgatagcacg gatacatcag cttcaagcga
    35941 cagtacagat actacctcta ccacaagtga tagcacggac acatcagctt caagtgacag
    36001 tacagatact acctctacca caagtgatag cacggacacg tcagcttcaa gtgacagtac
    36061 agatactacc tctaccacaa gtgatagctc agattcatct accactacaa gtgatagcac
    36121 ggacacgtca gcttcaagtg acagtacaga tacatcctct accacaagtg atagctcaga
    36181 ttcatcaact tcaagcgata gtacagacac gtcgtctacc acaagcgata cacgtcatgc
    36241 aagtgtctcc ttctcaaaaa caagttcgga taacaggacg aactttaact taactaataa
    36301 aacaagcaat gacaatggaa acaaatcaaa aagagcactt cctaaaactg gaagtcaatc
    36361 gaataattgg ataacactcg caggcgttat attacttgta atcggtttaa gaatcacttt
    36421 tatgagttat aagaaatcga aaaggtaaaa aaatattcaa gataaaaaag agcaacgtcg
    36481 ctaacggacg ttgctcttta tttttgcttt ttatcataaa tacaagaact acaattcaat
    36541 ttgtcaaaaa acacgtagat ttccttctga gaaatttatt tacgtatcga acctttccct
    36601 attcagtctt tgcgatccaa aatcagttgg gtaagggaaa agagattctc ttttgttcga
    36661 agagaggtgg caggtaattt ctttatttcc ttcaaagcct tttctgtgta agaggccgct
    36721 aacttcctag cttcttccac gcctcctgta tgttcaacga ttttgcgtac ggcgtcgaca
    36781 tcttcttctg tcattgccgc tttcttctct aaataaggta gtagctttgg tttgtttttt
    36841 tgcaaagagt agatcaacgg taaagaatag accccttgac gcatgtcttc tagtacaggt
    36901 ttgccgattt cctggctctc ttttgtataa tctaaaatat catcgataat ctgaaaggcc
    36961 atcccgatag aaagtccgat atctcctgct ttttttgcga agcgctcgct tgttccactt
    37021 tcaaaagcgc caacagaaca acttaattgg aacagttcag ctgtcttacc tgaaatattt
    37081 tccaaatatt cttttacaga aagttcataa ttatagcgat catccatctg ccctaattcg
    37141 ccattcaata ctttttccat actgcgagaa ttcaattgga gacttttcaa ggaagtggag
    37201 taatcagaca atagtttaaa acagcagaca aataaatagt ctcctgcata gacagaaacg
    37261 acattaccaa actgactacg gatattaggc tgaccacgtc gcagatccgc ttcatcaacg
    37321 atatcatcat ggatcagtgt ggccgtatgg agcatttcga tagaagctgc caaagcgatg
    37381 gctttgtctc gatcttgctc tggtccaaat tgtgagaaca atagctgata ggcaggacgc
    37441 aacagctttc cgccggcatg gatcgtttct ttgattgctt gttcgacagg tttgtttttc
    37501 aggcggacag tttcttccat ccgttttagt gtttctgtca attctttact taaagcagga
    37561 tagttttccc acattggatg tagcttcata aaaaaactcc ttgtgtgacg attatttttt
    37621 ggtaaacatt gggctccatt tttgtttggt tccctgctca taatcttttt ggaatcgttg
    37681 aagtgtctgc acatgtcgta aaagataatt cgctgcgatc ccgattgcaa tccctgataa
    37741 aatccctaaa actgaaagga ctggcaagta caacatgact gtccatgatt gtgcaatgaa
    37801 agaagccatc aaaagctgtc cgacattatg catgaaaccg ccggccgcac taattccgat
    37861 gatactgaca cgttttggtc ctaattgctt gaccaataac attccaaaat aactaagcaa
    37921 agcaccactc atactataaa ggaatgtgga aatcgttccg cctagcaaag tagtcaggaa
    37981 tagtcgtagc caaagtagta agaagctgtc ttgttttttc atggtaaaaa tggcaacgat
    38041 cgtgattaga ttggctaagc ctagttttgc accaggcgca aaagaaaaag gataagggat
    38101 catattttcc aataaaccaa tgatcactcc ttgtgcaaca agtagcgaaa tataaatcat
    38161 tttttgtaat ttactcatgg tgtgtaaagg tctaataaat cagactgtct tcgtcacctc
    38221 catctgttga acggacttcg atcactaatt tatgtggcaa acagacgatg gtttcgccat
    38281 ttttcgttgc ccagcctcga cgtacgcaga tctggtcatc gcaatctgct tcttttatcc
    38341 gtactcgatc gccatctatc tcgatcaagt tataatctcc gtgttcatct ttgtaagtat
    38401 atgtgttgct ctcttctcca gccatcaaag ggaatgtttt gatttctgtg ccatccacac
    38461 gcagtaccgc ttctttttct gctgttgcgg tgttttgctg aagaccaaaa atcatgactg
    38521 gtaaaaaaga aagaacagtc aaaagcaaaa taataaaaac atcccaaggt ttgagcagac
    38581 ttttttcagc aaattcttta aggctcattt ttgttctcct ttttccagat taactcaccc
    38641 aattttagca taaaaacaag aggttgtgac acctgtgtct tgctttgagt aataagaacg
    38701 aagaatagaa aacagctttc catgttttct aattctttgg gcttattacc gagaagcagc
    38761 aggtggaaca ccgtttataa caagaggttg tgacagaagt gggcaacttc aagaaataag
    38821 aaggaattta cgaaaattac ttttcaagtt tttgtgaaat ttcggcttat ttttcgaaga
    38881 agctacttct ggaacaccgt ttataacaag aggttgtaac agaggttgtg acacctgtgt
    38941 cttgctcatg gaggcttatc tcgggcatct tattccttta attttacata aaaaggaggc
    39001 tgtgacggtt tgtctcagcc cctttctatt gaaatcttgc attcaaataa cgttctttat
    39061 ctatttattt cttgccgtac tgggaacttg gtctaccgta ccaccaatta cctagtgtac
    39121 gttgtagcca tggaattacc cagcgatcca acccaatcgc acgtccggaa ccgttcatca
    39181 atgcgaaagc aacaaaaatg aaccaaatgt ttacccagta aaacatgcct gataagcaga
    39241 acgtgatcac caatacaatc gttgtcgcac tgcatagcca tgtgaataat ccagcaatca
    39301 atgctaatgc caaggcaatt tcaaagaata ccatgaattt ttggaagaac attgctacat
    39361 cattgtttgg catgatcact tgcatgatct ttgtgaacca gtctggtgac ttctcaatca
    39421 cagccattgg ttcttcaccg tatgcataac tcaaaccaaa atgtgcagct tgagtcgctg
    39481 cttctccggc acttgcccct gctccgctgg cagctgtggt tgcatcacca gcagcagaag
    39541 caccactggc aacatctgtt acattgtatt cccatgtcca agggaacaca ctgtttccag
    39601 tgaaccatga tccttcacca aaccaagtac ttggtttgaa cacttcacca ttcccaatga
    39661 tttttttgga agcttcaacg aaccaaacta aaccatagaa aatacgaagt ggcacactcc
    39721 ataagacatt gccgtaacga gaagaatgtc ctcgagtcac gttgcgatca tctttgatat
    39781 ggaaaaactc atgcattaaa tattggaaca tataataacc agaacgaata tcaaagaagt
    39841 atttcaaatt cacgatatgt ttcattacga tagctaaaaa tccgcttaaa tggatcttat
    39901 caaataggtt agctaccccc catttggcac caatagaaac cataaatcct tgatagtttc
    39961 ctttaaattt atgcttttct ccgcctttga tcgaagccac gatattcgct gcggctgtgt
    40021 gtcctgtttg ttcagcagct tgaacgatct gcggtgtcgg tgttcctggg aattcttcat
    40081 aaaagactaa atcaccaatg atatagatgt ttttatcttc gtagcctttt gcctgcatat
    40141 attcattggc gatcaaccgc tgtccgcgtg ctgattctaa tccaaagtca gcagcgtcag
    40201 aagttccttt gacaccagct gtccaaatca gtgtgtgagt cggaatgttg cgtccgtctt
    40261 tcaatttgat atgatcagca gccacttcta cgattggtgc attcaataat aattccacgt
    40321 tgtgcttacg caaatagcgt tcagcttttg cagcatcatt tcgatccaac atattcaaga
    40381 tcgtcggcat tgcctctacg accatcagtg tgatttcgtt tggatctaat ttataatctt
    40441 tggctaggcg atttttccag tcgatcagtt ccccaatcat ttcaataccg gtaaatccag
    40501 aaccacagac aacgaaagtc agcatggctt tacgcagttc atcatctggt tccaatgcag
    40561 cttttgctac tgtcttctca atatgttccc gaatccttac agaatcttca aatgaccaaa
    40621 gggtgaatcc gtgtgctttg acaccaggtg taccaaagtc attcggctct ccgcccattc
    40681 caaggatcag ctgatcaaaa ggataggaac ctaatttggt cttgacgatt tttcgttctt
    40741 tatcgatacc gattacagtg tctgtgacaa gttgtacatt cttttgacga gcaaacaaat
    40801 gctgcagatc gtattggatt gcttctggtt ctacacgtcc gccagctact tcatgcaact
    40861 cggtcatcat agtatggtac gaatgacgat cgatcagagt aattgctaca tcttcttttt
    40921 tcagtttctt tgccaagtat tttgtagctg aaacaccggc atatcctgct cctacaacga
    40981 caatattttg ctttgccatt gatcatccgc tccttataga ctatctatat aatgaatata
    41041 tgataattct tttagtttga tacttattac acaatctcca tatattatat agatgttctg
    41101 ttcttttgtc taactccttt tggatttttt tcaaatttta aaataaagcg ttttttcacg
    41161 aaatttgctg aaagaaaacg tttgaaatat tacatgggtt atttatcaaa aatagttgac
    41221 ttataggcta aaaagattag aatgtataat gaatcacaaa gaaaaattgt ggactagaaa
    41281 tggaatggtg gggtattaaa atgaagaaaa aacgttttgt aactggattt gccgtattag
    41341 cattttcagc tctagtgtta ggcgcttgcg gcgcagatga caacggaagc tcaaactctt
    41401 cttctgaatc atctacagca caatcttcga ctgcaaaaag cacaacagaa tcatctgcaa
    41461 aagttgtagc tggcggagat ttgcaagacg gcacatataa attagaagaa aaaaattatt
    41521 caaatggtta ccgtgcagtc tttgaaatgg ttgtaaaaga cggcaaaatc actgaatcaa
    41581 aatatgataa cgtcaatgaa aacggcgaat caaaaacaaa agatgcagaa tacaacaaaa
    41641 acatggaagc aaaatctggc acaaacccag aaaaatacat tcctgagttg aatgaccaat
    41701 tcttaaaagc acaaagcgca agcggtgtgg aagtcgtaac tggagctact cactcatctg
    41761 aaagcttcca aaactacgca caacaattga tccaagctgc tcaagctggt aacacagata
    41821 caatcgaaat cgacaatggt gctgatttga aagacggcac ttacaagctt gaagaaaaga
    41881 actactctaa cggctaccgt gtgcaattcg aaatgacagt tgctggcggc aaagtaactg
    41941 aatcaaactt tgattatatc gacaaagacg gtaaatcaaa acaagatgat acagaatata
    42001 atgaaaatat gaaagcaaaa agcggtacag aaccaaaaac ttacatccct actctgaacg
    42061 acgaattcgt caaagcaatg ggcgaagaag atggctcacc tgctaatgta gaagttgtta
    42121 caggtgctac acacagctca cattcattca tcatgtacgc acaacaatta gtgaatgcag
    42181 ctgaaaaagg cgacactcaa acaatcgaag tagataatat cgtaacagaa aaataatcac
    42241 ataatcatac taataaaagt tggagggtgg gacgatagcc agattaggca gtcgtctcac
    42301 ctttcaaaat gaagagagga aaaagatgcg gaaaaaacta ctattttcct taatcacact
    42361 gggcatctct tttatggtgc taactggctg cagcaactca gcaaataaaa caaccactga
    42421 aagttcagca gctaccaaga tattgaaaga tccatattct gatgaacagt tcttgttagg
    42481 gacttacgtt cgtatccgtg tgtatgatga aggcaaagaa tcagcattga aacctgcctt
    42541 cgatcgagta aaagaacttg gtgataaaat cacgatcaat caaaaaggtt ctgagatcga
    42601 tgaagtgaat gagcaagctg ggatcaaacc agtaaaagtt tctgatgacg tctacacgtt
    42661 agtcaagcgg gcctacgaat atagccaaga ttctcaaggc ggattcgata tggcgattgg
    42721 tgcaatcaca caattatggc gaatcggttt tgatgacgcc agaaaacctt cccaagaaga
    42781 aatcgatcag gcattgaaat tagtggatta tcataagatc gaactaaatg acaaagaaaa
    42841 aactgtttat ctaaaagaaa aaggaatgat catcgattta ggtgcaatcg ccaaaggtta
    42901 cattacggac gaagtagtga aagtcttgaa aaaacaagga gtgaccactg ccatcgttga
    42961 cttgggcggt aatgtctatg tcttaggcca cagcccaaga ggcgaaaacc aagactggac
    43021 agtcggcatc caagatccga acatggctcg cggatctgtt ttaggttcta ttaaagaacg
    43081 gaacaaaaca ttagttacct ctggaattta cgagcgttat ttagaagtag atggcaaaaa
    43141 ataccatcat ttgtttgatc caaaaacggg ttatccgttc gacaatgata tcgcaagtgt
    43201 cacgatcata acagataaat caattgatgg tgacgggttg tctacagcag tcttttcaat
    43261 gggtgtgaaa aaaggactgg aatacgtcga aagcgaattg aataacggga cggaagcgat
    43321 cttcgtgaca aaagacgata aagtatatgt gaccgatcca atcaaagaca ccttcaaatt
    43381 atcggaggac tcccattaca cgatgggtga ccgttctgaa ctaaaataag gagtacgaac
    43441 catgacacta aaaatctttt tagaagtagt tgaaatacga acaaaggtgg ctagtgtatt
    43501 tccttttgcg gtaggggtat tattctctat cgcttttttt catgagatac attggctaaa
    43561 cactttttta ttttttattg gaatgctagt ttttgattta gcgactaccg ctatcaataa
    43621 ttacatggat tatgaaaagg ctcattctga agtatataag tatgaagaaa atgtcattgg
    43681 ccgcagaaat ctatctcctg tattgattcg aaacatgatt ttagctatga ttgcatttgt
    43741 ttttgttatc ggcgttattc taacgatcaa tacgggttgg cttttacttt tgatgggatt
    43801 tatctgttgt tttattggag tattctatac attcggaccg attcctttat ctcgaatgcc
    43861 tttaggggaa attttcagtg gggtgactat gggccttgga atttttgcca tggtcgttta
    43921 tgtcaataca ttcggttcag atgtctatga tctgacagtc aacttttcat ctggacaatt
    43981 tgctttggta ggaaatcttt gggctatagc agcaatcgta ttagcttcct tacccttggt
    44041 gtttacgatt gccaatatca tgttggctaa taatttgcgg gatcttgacc gtgatattga
    44101 aaatcatcgc tatacactag ttttttatat cggacgtcct gcgggaacag tcttattcca
    44161 gctattgatg tatgcttgct atttcgtgat tttaatgggg ttgttgagcg gtatctatga
    44221 atggccgatc ttggtcacct tcttgacctt gccaattgtg aagaagcatt tggatcaatt
    44281 caagcaaacg ttaccccagc ctatcagttt cagctattcc atcaaaaata tggtcttatt
    44341 caatgccagt tatgtattgg ggctattact aacaatcatt atgcaagcca tttaacagca
    44401 tgaagaggtt gtgaaaaaac tgccctgcat caagtaataa gaacagccaa ataaaaatag
    44461 ctccttatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    44521 ttatcaggag gttgtgaaaa agtcgcttag tttcgagtat taagaaaaat tttgtgaaaa
    44581 tggctttcca catttttgca taaatttggc ttaataccga gaaactggct tttgaacacc
    44641 gtttatcaga ggttgtaaaa tcagtgtttt gtcctgagta ttagagaaac aaatggaaaa
    44701 atagttcctc atattttgcc gttttttgag ctaataccga aggacagctg attgaacact
    44761 atttgttcgg aaaaagtgac taactatgac acaatttttt tcacagtccc ttttttcact
    44821 tgatttgatt cgtaccagcg aacttgacga gaactttctt ggtttggtaa ctatatggta
    44881 ttcttttaac atcctcgttt gcttcttcta atttatttat acaaagtcac acttttttaa
    44941 acatctgttc ttcgatacat ttctatttct tttaaacatc gataccaata ttttgaactt
    45001 aagagtgcat accaaatgga ttcatttact cttcgtcagt tacgaagata atcaaaatct
    45061 ccaacttccc tacttatttc gttttgagaa ttatcgaagc aatcttacat aaataactaa
    45121 aaaacaaaaa accagaaaat cagtatactg attttctggt tttacatggt ttgttcaata
    45181 aaaagctgtt ggaactgtta atattaaatt atcgcatcgt tacgaattct tccgctcctg
    45241 ttggatggat ggctactgta ttgtcaaagt cttctttagt tgcacccatc ttgatagcca
    45301 cggcaaaacc ttgcagcatc tcatcgacac caacaccaat agcatgtaag ccgacgattc
    45361 tttcttcttt tccgacacag atcaatttca tttcgcattt ttggcgataa tcatttaatg
    45421 caaagtacat tggggtaaag cgtgaacgat aaactttcaa ttcattttcg ccatattttt
    45481 ccaatgcttc ttcttctgtc aaaccaattg ttgcaattgg tggatgcgta aagacgactg
    45541 tcggaacaag tttatagtca agataagaat ctttctttcc attaaataaa cgttctgata
    45601 aacgtctacc agctgcgatt gcaacaggag tcagatctaa tttaccgatc acatcaccaa
    45661 cagcaaaaat atgttcatcc gttgtatttt ggtatttatc tactttgata aacccttttt
    45721 tgtccaattc cacatttgta ttttccagac ctaatttttc ggtattcggt acacgtccac
    45781 cggcaaaaag tacacaatca ccagttaagg tttcaccatt ttcaaatagc accgtatatt
    45841 cgtcattgtt tttagtaatt tctttagcaa tatgatgtgc gtaagttttt attccagctt
    45901 cttggtacat ttggatcaaa ttgtccgaaa gcattttatc aaacgttcta agtggtcgtt
    45961 cttttcgata tgcccacatg acttcactac ctaaaccacg aaatacacct gaaagttcag
    46021 ccgcaatgta tccagcacct aaaacgattg ctctcttagg taactctgtt aattcaaaaa
    46081 atccatttga atcaattgcg tattctccac caggaatggt cattttactt gcacggcctc
    46141 cagtagcgat caagatttta ggagcacgat aggtttcacc gtttacttcg atcgtttgac
    46201 tatcgataaa agtagcgtaa ccttttatag cctcgacatg attgctatct aatcctcttt
    46261 gataagcacc gtgtagaaaa tcaatatatt tttctcgtct ttctactaga ccggcgaaat
    46321 caacattttt taaatctgct tggataccgt aacttgaggc atctcgttca attgtttcca
    46381 aaatcgtact tgcttgccac ataacttttt taggtacaca accgacgttg acacatgttc
    46441 cgcccaattc attcgcttca atcagcaaaa cttttgcgcc atgcatccct gctctgtttg
    46501 ctgaagcaat accgccagag ccgccaccaa ttacgatgta atcatatatt tgcattttgt
    46561 tcctccttat tgaagagatc aatcaaaacc tttatttaac gatccttttt ctacagaaaa
    46621 caagtgtaac acttttcttg aattttgtat gcgaagatgc ttaaaacagg gatatatcag
    46681 ctttttcctt atttacgttt tcggatcata tctccaggtt tcaccggctg tgcgactggc
    46741 atagttaaaa tcatcattgg atttggtgct cggtcaatgg attcgccttc ttcattatgc
    46801 ataacttcaa cggtttgact gaaatgactg aatcctggac cataaaattc gatttcatct
    46861 cctacagaaa acaagtttct ctgacgtatc gtagcaatct gtgttgcctc atcataagat
    46921 aatacttcac cgacaaattt atatactggg attttacgac gttcaccgaa taattgttcg
    46981 ttttcagttg gtgtattgta gtaaaaacct gtagctaatt ctcgttgtgc tactttccat
    47041 aactcgtcga tccattcttg cttgcagaca tagttttcag gatcttccat ataactgtct
    47101 acagccgctt tatagacatt tgacaccgta gatacataat ggatcgattt cattcttcct
    47161 tcgatcttga agctgtctac gccgttttca atcaattctg gaatatgttc gatcattgac
    47221 atatccactg cactcatcga gaattcttct tccacttcgc ctgtatcagt taaactgttt
    47281 cgttcttgac caaaaggcat atcgaacaat ccatacttcc agcgacaaga ttgagaacat
    47341 ccgccacggt ttgcatcccg catcgacata tggttggaca atgtgcatcg accagaataa
    47401 gagatacaca tggcaccatg gataaatgct tcgatttcgg tatccgtatt tttacgaatc
    47461 tctgccactt cctccattga aacttcacga gctaaaacga cacgttccaa cccttcttct
    47521 ttccagaatt ccaatgtctc aaaattagtt gctgaagctt gagtggataa atggatcggc
    47581 agacctgggg cttctgtcgc acaaatttcg atcaaagctg gatcagaaac aatcactgca
    47641 gaaataccga catcacgcaa actgcggaaa aattcccctg ctccatcttc atttccttca
    47701 tgggtgacca tattagcagc aacgtatacc ttcgcatcat gttcttttgc aaaagcaact
    47761 ccttcagcca tttcttcata agtaaaatta cctgcacggc ttcttaaacc atatgcattc
    47821 ccgccaatat atactgcatc tgctccataa tggatcgcgg tttttaactt ttccagtgtt
    47881 cctgctggcg ctaggatttc tggtcgtttc aattttcttt ttactgtcat ttctttcatc
    47941 atactcctta tttgatagca gaaggatcaa tataaaagaa tcctgtatct aattcacggt
    48001 tttcaggatg caatttactg atttcgctag tcattttttc cgctttttct tgatcccagc
    48061 taccttctaa aatttgtttt tttgcttcgg cgaatagtcg agtgatgttt acgaattttt
    48121 cgcctggagt aaataatccg tccaatttcc atgtacagta atgatgctga taaagttcat
    48181 tcaattcatt cgagagattc agatcattgc tggcaaaaat atgtgtgcca tgactatctt
    48241 cataaataga ataatgtgtc tcttcttttt taggttccga gataaaaaga cctctttcac
    48301 gatctttttg ttcgtcttgt ttcgtatagt tatagtaatt ctgtagcagt ggacgtttgg
    48361 attgatggat gcatgtagca ccatacacaa gggtttctac aggaatatcg agtttttctt
    48421 ccatcgcctt catctcttca aaaggaactt cacgagcaag tactgctcca actgcgcctt
    48481 ttttcgccca gaaattgatt tgacgtgcgc tcgttactaa tgtttcagca tcataaatat
    48541 acggtatacg caattcagga ttttttttca tcgtataaat aatacctgta tcaccaactg
    48601 tgatcacatc tacgtttatt tcttttaaaa aagccaaata ttcaggtaca tttttcattt
    48661 tttcaggatg aatgatccca tttacagcaa tattcgcttt tttaccatac ttgtgtgcta
    48721 attctaccaa ttgtcgctgt tcttctcgtg taaatgaagc aggcagacgc aatccaaatt
    48781 gctcttcacc gaaatatagt gtatctgcac ctgcagcaag caactgttct gcttgttcaa
    48841 tagtttctac tgtggttatg agttcgatca taattttctc ctcctacaac ttcataatag
    48901 tagcatagct ctaaaaactt tccaatactt cttctattta aagtcggatt tttgaaaatt
    48961 atttcacaaa aaatcaaaat aaagttcgat atattctgtc caaatataaa aagagattgt
    49021 gacaaaaatc ttgtcacaac ctcttaatca agtcttacta ttataaaaat tcagctacac
    49081 aggccaagta actataggga acctactgtt tcctttttag gtccgcgaac attcaatgtg
    49141 atcttacctt ttgaagcacc tactgttacg tggtcaccta aacgaatttc tccgccaagc
    49201 aaagcctcgc tcaatcgatc ttcaatttct ttttgaagtg cgcgacggat tggacgtgca
    49261 ccatattcag gatcaaatcc agctttcccg atcacatcga ttgcagatgg tgtgattttc
    49321 acttgaatat cttgttcttt caatcgtttg ataatcgctt tgctcatgat ttggacgatt
    49381 gtatggattt catctttact caatgaatgg aagacgacag tctcatcgat tcgattcaag
    49441 aattcaggtc ggaaagcttt ctttaactct tctaagatac gtttttgcat ggctttgtga
    49501 tctttagtaa catcttggac attgaatccg acattttttt cttctcgaat ttgtgtcgct
    49561 ccgatatttg aagtcataat catgattgta tttctaaagt ccacttttct acctttagaa
    49621 tctgttaaat gaccatcatc caatacttgc agaagtaaat tgaaaacgtc tggatgtgct
    49681 ttctccactt catctaagag aatcactgaa tatggttttt gacgaatttt ttctgtcaac
    49741 tgtccacctt catcataccc tacgtatcct ggaggagacc cgattaatcg gcttgtactg
    49801 tatttttcca taaattctga catatcaaca cggatcaggg catcttcact tccaaacatg
    49861 acttctgaaa gtgctttggc caattctgtt tttccgacac cagttggtcc aaggaacatg
    49921 aatgaaccaa ttggacgatc aggatctttc aatccgcttc gtgcacggcg gatcgcacgt
    49981 gaaactgctt tgacagcctc atcttgacca acgacacgtt catgcagaag tccttccagt
    50041 tctaacaagc gttcgctttc ttttttctcc aactgctgta gagggacacc agtccactcc
    50101 gatacaactg tagcaacatc ttcttctgtt acacgatcag aataaccttg ctcctgtttt
    50161 gcttcaattg cagaaacttt ttgcagcttt ttacgtagtg ctttttcttg tctgcgtaat
    50221 tgagcagcat tttcaaagtc ttgtttttgg atcgctgctt ccttttcttg tactagttca
    50281 tcgatttcta gtttgatcac agttgatttt gttaagtgat cggtttgatc caaacggact
    50341 ttcgctgctg attcatcgat caaatcaatt gctttatcgg gtagttgacg agaagtgata
    50401 taacgaacag aaagattgac tgctgctcgt acagcttcat ctgtgatctc cactccatgg
    50461 tgctcttcat atcttgtacg taatccttga agaatcactt ctgcttcttc aggagttggc
    50521 tcatctactt gaatgcgagc aaaacgtcgc tctaatgcag aatctttttc gatatatttt
    50581 tgatattcat ctagggtcgt tgctccgatc gtttgtaatt ctcctcgagc taacgccggt
    50641 ttcaagatat tcgaagcatc aattgctcct tctgctccac ctgcaccaat taaggtatgc
    50701 aattcatcaa tgaataagat tacttgacca tcattataga tttcgtcgat gacctttttc
    50761 attcgatctt caaattcacc gcgatatttc gtaccagcaa ccaaagatcc catatcaagc
    50821 atcatcaggc gcttttcttg catgtcttct ggcacttcac ctaaaatgat tttttgagct
    50881 aacccttcag caatggctgt tttgcctaca ccaggttcac ccaccagtac agggttattc
    50941 tttgtccgtc ggctaagaat ctggataagc cgtttcactt ctctcgaacg accaacaact
    51001 gggtccagct tgttttcttt tgctaatttc gtcaaatcac gtgctaatga atctagcgta
    51061 ggtgttcctt gcggtgtttg ccgtttatct tgtacattta catttctacg acgattcatt
    51121 ccttttccag cagaatcacc agctagcccc attttttgtt tcagaacttg acgggctttt
    51181 gaaaggctga tacctaagtt gatcatgatt cgagtagcca tgatactttc atcttttaat
    51241 aagctcatca aaatatgttc tgttccaact ttttgagaac cagttttctt cacttcgctg
    51301 ctagctaaag caaaaacttg tttcattctt ggtgaatatg gaagaaagac tcctttaggg
    51361 taagaacgga taccaccata accaatcaga tgttcaattt cttcataaat ttccgtttca
    51421 ttcaaatcca tttcacgtaa tacttttcca gcaattccat tttgctcgac cactaaggct
    51481 agtaaaacat gttctgaact aactgattga tgtttcaacc gttttgcttc ttcttgtgca
    51541 atttctaata ctgcttgggc tctttcagta aaaagttctt ccatctaatc tcacttccca
    51601 tcttcataac ttaaacgttc cagaaatgct cggagaatcc gagcacgtgt atgatcttca
    51661 tattcattga aattcaatgt gttttttgca attgcactca acatcaagtt tccttctttt
    51721 tttgtaatta tttggtcttc ataaagtttt tgaataatag caaaagcatt tttctcactg
    51781 attgtatcat caaataactg atttatctgc tcaagtaatt gttttttatc tgaaatcctt
    51841 acttttgcaa ttcgtatata accaccacca ccacgtttgc tttctactag ataaccacgt
    51901 tggatggtaa aacgggtatt aatcacatag ttgatttgtg aaggaacaca gttaaagagg
    51961 tctgccattt caatccttcg aatctcgatc atttcactat tttccagaat tttctttata
    52021 tatgattcaa ttaaatccga ggtattctga tgtgccatct tattcattcc ctttgactaa
    52081 tattgacctt aattataacg aatttgataa tagaaagaaa gaagaacgct ttttgttaaa
    52141 taaatccttt agaatcaaca aaaaaaaata cggaatatac tattccgtat cgacgc
//
LOCUS       DAZKPE010000012        49431 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000012 DAZKPE010000000
VERSION     DAZKPE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.012"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..2730
                     /gene="adhE"
                     /locus_tag="ACG930_000806"
                     /gene_synonym="adhC"
     CDS             133..2730
                     /gene="adhE"
                     /locus_tag="ACG930_000806"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFQ0517984.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            2959..4065
                     /locus_tag="ACG930_000807"
     CDS             2959..4065
                     /locus_tag="ACG930_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFQ0517985.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            4082..5110
                     /locus_tag="ACG930_000808"
     CDS             4082..5110
                     /locus_tag="ACG930_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFQ0517986.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            5116..5595
                     /locus_tag="ACG930_000809"
     CDS             5116..5595
                     /locus_tag="ACG930_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFQ0517987.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            5611..6906
                     /locus_tag="ACG930_000810"
     CDS             5611..6906
                     /locus_tag="ACG930_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFQ0517988.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            6917..7741
                     /locus_tag="ACG930_000811"
     CDS             6917..7741
                     /locus_tag="ACG930_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFQ0517989.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            7906..8805
                     /locus_tag="ACG930_000812"
     CDS             7906..8805
                     /locus_tag="ACG930_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0517990.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(8931..9800)
                     /locus_tag="ACG930_000813"
     CDS             complement(8931..9800)
                     /locus_tag="ACG930_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0517991.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            9953..11413
                     /gene="rhaB"
                     /locus_tag="ACG930_000814"
     CDS             9953..11413
                     /gene="rhaB"
                     /locus_tag="ACG930_000814"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFQ0517992.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            11410..12666
                     /gene="rhaA"
                     /locus_tag="ACG930_000815"
     CDS             11410..12666
                     /gene="rhaA"
                     /locus_tag="ACG930_000815"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFQ0517993.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            12680..13525
                     /gene="rhaD"
                     /locus_tag="ACG930_000816"
     CDS             12680..13525
                     /gene="rhaD"
                     /locus_tag="ACG930_000816"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFQ0517994.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            13527..13838
                     /gene="rhaM"
                     /locus_tag="ACG930_000817"
     CDS             13527..13838
                     /gene="rhaM"
                     /locus_tag="ACG930_000817"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFQ0517995.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            13920..15071
                     /gene="fucO"
                     /locus_tag="ACG930_000818"
     CDS             13920..15071
                     /gene="fucO"
                     /locus_tag="ACG930_000818"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFQ0517996.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            15198..15956
                     /locus_tag="ACG930_000819"
     CDS             15198..15956
                     /locus_tag="ACG930_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFQ0517997.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            16056..16700
                     /locus_tag="ACG930_000820"
     CDS             16056..16700
                     /locus_tag="ACG930_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFQ0517998.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            16707..17714
                     /locus_tag="ACG930_000821"
     CDS             16707..17714
                     /locus_tag="ACG930_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFQ0517999.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            17730..18572
                     /gene="kduI"
                     /locus_tag="ACG930_000822"
     CDS             17730..18572
                     /gene="kduI"
                     /locus_tag="ACG930_000822"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFQ0518000.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            18592..19395
                     /locus_tag="ACG930_000823"
     CDS             18592..19395
                     /locus_tag="ACG930_000823"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFQ0518001.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(19644..20708)
                     /gene="fni"
                     /locus_tag="ACG930_000824"
     CDS             complement(19644..20708)
                     /gene="fni"
                     /locus_tag="ACG930_000824"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFQ0518002.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(20705..21790)
                     /locus_tag="ACG930_000825"
     CDS             complement(20705..21790)
                     /locus_tag="ACG930_000825"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFQ0518003.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(21803..22780)
                     /gene="mvaD"
                     /locus_tag="ACG930_000826"
     CDS             complement(21803..22780)
                     /gene="mvaD"
                     /locus_tag="ACG930_000826"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFQ0518004.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(22773..23717)
                     /gene="mvk"
                     /locus_tag="ACG930_000827"
     CDS             complement(22773..23717)
                     /gene="mvk"
                     /locus_tag="ACG930_000827"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFQ0518005.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            24033..24692
                     /locus_tag="ACG930_000828"
     CDS             24033..24692
                     /locus_tag="ACG930_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0518006.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            24777..25682
                     /locus_tag="ACG930_000829"
     CDS             24777..25682
                     /locus_tag="ACG930_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0518007.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(25684..26316)
                     /locus_tag="ACG930_000830"
     CDS             complement(25684..26316)
                     /locus_tag="ACG930_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFQ0518008.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    26467..26592
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            26636..27160
                     /gene="infC"
                     /locus_tag="ACG930_000831"
     CDS             26636..27160
                     /gene="infC"
                     /locus_tag="ACG930_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFQ0518009.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            27232..27432
                     /gene="rpmI"
                     /locus_tag="ACG930_000832"
     CDS             27232..27432
                     /gene="rpmI"
                     /locus_tag="ACG930_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFQ0518010.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            27485..27844
                     /gene="rplT"
                     /locus_tag="ACG930_000833"
     CDS             27485..27844
                     /gene="rplT"
                     /locus_tag="ACG930_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFQ0518011.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            28096..29434
                     /locus_tag="ACG930_000834"
                     /pseudo
     CDS             28096..29434
                     /locus_tag="ACG930_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            29482..31611
                     /locus_tag="ACG930_000835"
     CDS             29482..31611
                     /locus_tag="ACG930_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFQ0518012.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            31586..32275
                     /locus_tag="ACG930_000836"
     CDS             31586..32275
                     /locus_tag="ACG930_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518013.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(32683..33296)
                     /locus_tag="ACG930_000837"
                     /pseudo
     CDS             complement(32683..33296)
                     /locus_tag="ACG930_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(33432..33626)
                     /locus_tag="ACG930_000838"
     CDS             complement(33432..33626)
                     /locus_tag="ACG930_000838"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518014.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(33676..34116)
                     /locus_tag="ACG930_000839"
     CDS             complement(33676..34116)
                     /locus_tag="ACG930_000839"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFQ0518015.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(34120..34965)
                     /locus_tag="ACG930_000840"
     CDS             complement(34120..34965)
                     /locus_tag="ACG930_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFQ0518016.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            35114..36532
                     /gene="pepV"
                     /locus_tag="ACG930_000841"
     CDS             35114..36532
                     /gene="pepV"
                     /locus_tag="ACG930_000841"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFQ0518017.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(36589..37536)
                     /locus_tag="ACG930_000842"
     CDS             complement(36589..37536)
                     /locus_tag="ACG930_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0518018.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(37759..38109)
                     /locus_tag="ACG930_000843"
     CDS             complement(37759..38109)
                     /locus_tag="ACG930_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFQ0518019.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            38309..39388
                     /gene="pepA"
                     /locus_tag="ACG930_000844"
     CDS             38309..39388
                     /gene="pepA"
                     /locus_tag="ACG930_000844"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFQ0518020.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            39532..39852
                     /locus_tag="ACG930_000845"
     CDS             39532..39852
                     /locus_tag="ACG930_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0518021.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            39874..40338
                     /locus_tag="ACG930_000846"
     CDS             39874..40338
                     /locus_tag="ACG930_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0518022.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            40543..41148
                     /gene="ytpR"
                     /locus_tag="ACG930_000847"
     CDS             40543..41148
                     /gene="ytpR"
                     /locus_tag="ACG930_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFQ0518023.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(41187..42476)
                     /locus_tag="ACG930_000848"
     CDS             complement(41187..42476)
                     /locus_tag="ACG930_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFQ0518024.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42904..43383
                     /gene="rlmH"
                     /locus_tag="ACG930_000849"
     CDS             42904..43383
                     /gene="rlmH"
                     /locus_tag="ACG930_000849"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFQ0518025.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            43468..43977
                     /locus_tag="ACG930_000850"
     CDS             43468..43977
                     /locus_tag="ACG930_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HFQ0518026.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            44077..44727
                     /locus_tag="ACG930_000851"
     CDS             44077..44727
                     /locus_tag="ACG930_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518027.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            45178..46116
                     /locus_tag="ACG930_000852"
     CDS             45178..46116
                     /locus_tag="ACG930_000852"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0518028.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            46129..47181
                     /locus_tag="ACG930_000853"
     CDS             46129..47181
                     /locus_tag="ACG930_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0518029.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            47447..48082
                     /locus_tag="ACG930_000854"
     CDS             47447..48082
                     /locus_tag="ACG930_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFQ0518030.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            48273..49064
                     /gene="msrA"
                     /locus_tag="ACG930_000855"
     CDS             48273..49064
                     /gene="msrA"
                     /locus_tag="ACG930_000855"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0518031.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        15696 a         8810 c        10571 g        14354 t
ORIGIN      
        1 aataaagcaa ttttatattt aaaaataact gtgaaaaaaa tcacaaaaaa gtgtttacat
       61 agaaaaataa atattgtatg atatacatgt gaattattta acaaataacc atgacccatt
      121 aggaggataa tgatggctaa agtaatagaa aaagaaaaaa cgaagacaat tgacgtacaa
      181 gcaatgattg atgatttggc agaaaaagca aatgcagcat tgaaagaaat ggaaagcttt
      241 gatcaagaaa aagtagacca tatcgtgcat gaaatggcaa tggcagcttt ggatcaacat
      301 atgccattag cgaagatggc tgtagaggaa acaggccgcg gtgtttacga agataaagca
      361 atcaaaaata tgtatgcgtc cgaatatatt tggcataata tcaaacatga taaaacagtt
      421 ggtgtgatca atgaagatgt ccaaaaaggg ttgattgaaa ttgctgaacc agtcggtgtg
      481 gtttgcggag taactccaac aacgaatccg acttccacaa cgattttcaa atcaatgatc
      541 gcgttgaaaa caagaaatcc aatcgttttt gctttccatc caagtgccca aaaatcttct
      601 gcagaagcag cacgagtggt acgtgatgct gctatcgctg ccggagctcc tgaaaattgt
      661 atccaatgga tcgaacatcc ttcgatcgaa gcgacttcta tgctaatgaa ccatccaggt
      721 atcgcgatcg tcttagcgac aggtggagct ggaatggtca agtctgctta ctctacagga
      781 aaaccagctt taggtgtagg tccaggtaac gtaccagctt atattgaaaa aacagcaaaa
      841 attaaacgtg cagtgaacga tttgatcgtt tcgaaaacat ttgataatgg aatgatttgt
      901 gcttctgaac aagctgtgat cgtggataaa gaaatctatg cagcagtaaa agcagaattc
      961 caagcacacc aagtttatat cgtaaaacca gatgaattgc aaaaattaga agatgcagtg
     1021 atgaacgaag gaaaatatgc ggtcaatcca tcaatcgttg gacattctgc gatggaaatc
     1081 gcaaaattgg caggaatcag tgtaccaaaa ggaacgaaaa tgctgattgc tgaattggaa
     1141 ggcgtaggcc cagattatcc gctatcaaga gaaaaacttt ctccagttct tgccatgatc
     1201 aaagctaaca acacggacca tgcgtttgat ttgtgtgaag gtatgttgaa tcttggagga
     1261 ttaggacata cagcagttat ccattcagaa aacgaagagt tgcatgtcaa attcggtctt
     1321 cgaatgaaag cttgtcgtat tttagtgaat acaccatctg cagaaggcgg catcggtgat
     1381 atctataacg aaatgattcc gtcattgact ttgggatgcg gttcttatgg taagaactct
     1441 gtttctcgta acgtctctgc tgtaaactta atcaatgtca aaactgtagc gaaacggaga
     1501 aataacatgc aatggttcaa attaccgcca aaaatcttct ttgaaaagaa ctctctattg
     1561 tacttagaga aaatggaaaa cgttgaacgt gtcatgatcg tttgtgaccc tggtatggtc
     1621 caattcggtt actgcgatac agttcgtgaa gtattggcac gacgtaaaaa tgatgtgaag
     1681 atcgaagtct tctcagatgt tgaaccgaac ccatcgacaa ataccgtata cgcaggaacg
     1741 aaactgatgg cagacttcaa gccagataca gtaatcgctc ttggaggcgg ttctgcaatg
     1801 gacgcagcta agggaatgtg gatgttctat gaacacccag acacatcttt ctttggtgca
     1861 aaacaaaaat tcttggatat ccgtaaacgg acatataaga tcgacaaacc agaaaaaaca
     1921 caattcgtat gtatcccgac aacatcaggg actggttctg aagtaacgcc atttgcggtc
     1981 atcactgaca gtgaaacaca tgtgaaatat ccgttagcag attatgcatt gacgccagat
     2041 gtcgcaatcg tcgatcctca attcgtcatg tcagttccag catctgtcac agcagatacc
     2101 gggatggatg tgttaacaca tgcaatcgaa tcctatgttt cagtcatggc ttcagattat
     2161 acacgtggat tgagcctaca agcaatcaag ttagtctttg actatttaga aaaatcagta
     2221 aaaacacctg atatggaatc acgtgaaaaa atgcacaacg cttctacaat ggctggtatg
     2281 gcgtttgcta acgcattcct aggtatttgt cactcagtcg cacataaaat cggcggggaa
     2341 tacgggatcc ctcatggacg gacaaatgcg attcttttac cgcatattat ccgctataat
     2401 gcaaaagatc cacaaaaaca tgcgatgttc cctaaatatg actatttccg tgcagataca
     2461 gattacgcag atatcgcaaa attcttaggt ctgaaaggcg aaacaacaga ggaattagtc
     2521 gaagctttag caacggctgt ttatgaatta ggaaaatctg tcggcatcaa catgagtcta
     2581 aaagctcaag gagtcacaca agaaacacta gatacaaccg tagaccgtat ggctgaatta
     2641 gcttacgaag accaatgtac gacagctaat ccgaaagaac cattgatctc tgaattgaaa
     2701 cagatcatca ttgatgctta caacggataa gcaaaagaaa gcgtagaaaa aagataagaa
     2761 aatagatgaa aaagaacttg gaaaacgttg tttctccaag ttcttttttt aatttccaag
     2821 taactgaaag ttacttttgt tatttaacat ttaggtcaat tttagacagt ttttgttcaa
     2881 aaagcgatat ttatagtgga cggtattact gctatattaa ggatataaaa tgaaagcgtt
     2941 taaaaaggtg gcgtaaagat gattattaaa gaagagattt ttgtacctaa agaattagtg
     3001 aaagaaaaaa ttgacctgct cgttgaaaac ctgacaacga tcaaagacga taatggtgaa
     3061 tttttgttgg actttgatgg actgaaagta gatgacaaaa gctggacagt gtggaattgg
     3121 ccacaaggtg tcggtctata tggtatttat aaaaattacc agatgacaaa aaatcctcgc
     3181 gcttatcaag tggtcaatga atggtttgag gatcgtatgg aagaaggcgc tccgcccaaa
     3241 aacgtcaata caatggcacc gctattgact atggcttact tgtatgaaga cacgaaagat
     3301 tcacgctatt tgccttattt agaacaatgg gcagaatggg tcatgaatga catgcctcgg
     3361 acaaatgaag acgggttaca gcatgccaca tatggaccgg aaaataagaa tcagttgtgg
     3421 gacgatacat tgatgatgac agtgcttcct ttggcaaaaa tcgggaaact gttgaatcgc
     3481 ccagaatatt tagaagaagc tcgttaccag tttatgatcc atatcaaata cttgatggat
     3541 aaacgaacag gattgtggta tcacggctgg acgtttgaag gaaatcataa ctatgccgaa
     3601 gcattttggg ctcgtggaaa ctgctggttg acgattgcta ttccagagat cattgaaatc
     3661 ttagaattat cgaaagaaga tgcattgcgc aaattattga tcgaaacact tgaagcacaa
     3721 gtgcgtgcat taaaaactta tcagtctgaa agcggtttat ggcatacgtt gttggatgat
     3781 ccttcttctt acgtagaatc ttctgcaact gcaggatttg cttacggtat tttgaaagcg
     3841 gtccataaac gttatttacc acaagaatat aaagaagtcg cttatcgtgc tatccaagga
     3901 ttgcttgaac aaatcgatga aaaaggagaa gttcaaaacg tttcaatcgg gacaggaatg
     3961 ggggacagtt tagattttta tcggaatatc ggaatcacag caatgcctta tggacagtcg
     4021 ttaacggtgc tttgtttgac agaattgctc gtctcttatt gttaaaagaa aggaaaccca
     4081 tatgaaaaaa acatcactgc tgtttgcagc aagttcgctt agcctaggtc tgctaggtct
     4141 aagcggctgc ggaaataatt ctagtgtggc aactgtcgca gatgcagatg taaatgagat
     4201 agttaccttg cgctttgctt atgcaagcaa cagccagcca gtaattgatg caatgaatga
     4261 atttgggcgt ttagtaaaag aaaaaacaga tggttccgta cagatccagt atttcccaga
     4321 tggacaactg ggtggagaac gtgaactgat cgaattgaca cagtcaggag cagtagattt
     4381 cacaaaagta agtgcctcag cgttggaaag tttctctaaa gattattcga ttttttcagt
     4441 tccttatcta ttcaatgatg aagaacattt ctttaaggtg atggataatg aagaaataat
     4501 ggagccaatc taccaatcga ccaaaaattt aggatttacc ggattgacct attatgattc
     4561 tggtcagcgc agcttttata tggtagacgg tccgatccat acgccggaag atttggaggg
     4621 aaagaagatc cgtgtgatgc aaagcgaaac cgctatcaaa atggtagagc ttttaggcgg
     4681 ttcgcccgta cctatgggaa gtgatgaagt gtacacgtct cttcaatcca atttgatcaa
     4741 cggatcagaa aacaatgaat ttgtcttgta tacagctgga catggtggtg tggctaaata
     4801 ctattcctat gatgagcata cacgtgtgcc agatatcatc atcatgaatg atgccatcaa
     4861 agaacagcta actgatgagc aggaaaaagc cattgaagaa gcagcgaaag aatcaacggt
     4921 ttttgaaatt gaagcttttg caaaagcaat tgaagaagaa aaagctttag cacaagaaga
     4981 acatggagtc caattcaatg atgtagataa tacaccgttt cgagaggcag ttgccccact
     5041 tcatgatata ttcaaaaacg atcctaccta caaagacctt tatcaaaaga tccaagagca
     5101 aggagcgtag ctgtgatgaa aatgatttta aacaaggtat tagagatcct gggagctgtt
     5161 ttgcttgttg ggatggtcgc tgttgtttta tggcaagtat tttccagaac ggttttagga
     5221 aatccaaata cggtcacgga agagcttgtt cgattcggtc ttgtctggtt tgccatgttg
     5281 tcttccgcgt atgttgtggg acaaaaagca catttagccg taacggtttt aagtgaaaaa
     5341 ttaactggca aaaaaagtaa aattttagaa gttgttgttc aaagtttatt tctggtattt
     5401 gctgcgatga tcatggtgta tggcggatgg aatgctgtca cattgacaat ggggcagatc
     5461 tcgccttctt taagtattcc tatgggatat gtttatctgt cagtacctgt atcgggggta
     5521 ctcatcatta tctatagcct gatcaatcta atcgatacat taagcaacaa gccagcaatt
     5581 caagaaaaaa tataaaaatg gaggaataaa atggcaatag aagccggatt agtgttattt
     5641 tttgtatttg ttgtgttgct tgtattaggg atgccgattg ctataagtat tgcattctca
     5701 tcgatgatga ctttattgtt agttataccg tttgatgttt ctgcttttag ttcagctcaa
     5761 aaaatggtgg gaagtatcaa tagtttttcg ctgatcgcta ttccgttttt cgttctctcg
     5821 ggcattatca tgaataatgg agggatagct aagaaactag tggattttgc gatgttgttc
     5881 gtcgggcgcg tgccgggggc tttggctcat acgaatgtgt tagggaatgc tttatttggt
     5941 tccatctcta gctcggccat tgccgcttct accgcgattg gcggagtgtt gatccctcag
     6001 caagtggaag aaggatatga ccggaagttt gcgacagcgg tcaatatcgc gtcagctccg
     6061 acaggtatgg tcattcctcc aagtactgct tttatcatgt attcacttgt tgctggtggt
     6121 gcttcgatct ctgctttgtt tatgggaggt tatctcgtag gcgctttgtg ggcgctagga
     6181 atcatgctag tagcattcat cgttgctaaa aagaataaat accctgttgt cgaaaaagga
     6241 cagatggctc atgctggaaa aataataaaa gaggcgattc ctagccttct attgattgtc
     6301 atcattatcg gtggtatctt gacggggata tttacagcag tagaagcttc agcgatagct
     6361 gtcatttact ccctgttgat tgctatgttt tactataaaa cggtaaaact aaaagatata
     6421 cctaatatgt tgtttcaatc agtagcaatg tcagggacga tcatgttctt attggctact
     6481 tcttccatga tgtctttcgc catggcgttt accggtattc ctcaggcaat tagttcgttg
     6541 attatgggcg taacggataa taaatttatt attctgttat tagtcaatct tgtgttatta
     6601 ctggtgggta tgtttatgga tgtggcgcct gctatcttga tttttacacc aatattttta
     6661 ccaatcgtca caagtgtagg ggttgatcct gtacattacg ggttgttttc aatcatgaat
     6721 ctgtgtgtag gctccatcac gccgccagta ggtacaggac tatatgtcgg tgcaagtgta
     6781 ggaggcgtaa aagcagaggc aatgctgaaa ccgcttcttc ctttttatgg ggttatctta
     6841 gtcgtcttgt ttttgattac ttacttcccg caaatcgtca tgtggctacc caatatgctg
     6901 agttaggaga atagttatgt tgaacattac aattagagga catgatcttt ccgaagtcca
     6961 aacgatagaa gatcttgcag aaaaaacaaa agaacaaggg attcatacac tgcagctcgc
     7021 cttaggtctt tcgtttcctg aaacaccttc tggcgcaaat gagatcaatt ctgggatggg
     7081 aaattatgtc aaacgagttt tagaaaagca agaagtgacc gtaggaattt taagttgcta
     7141 tatcaatatg attcatccag atttaacgat acgacaagag ttgctgacaa agttcgagca
     7201 gtatcttcgc tatgcttctt cctttggtgc gtcgatggtt gcttcggaaa ctggatgtgt
     7261 tttgccggaa atccaatata cggaagaaaa tttcacagat gaagcatttg ctgaagctgt
     7321 gtccgttatc cgtcgcttgg taaaagctgg agaaaaatac caaatgatgg tggggataga
     7381 accaggtttg aatcatccgg tgtattcttt agcaagggta gagcagctga tccaagcagt
     7441 agattcggac tatctaggaa tcattttaga tccgaccaat ttgatcacaa gtagtgatta
     7501 tcaagaacaa gtccaattgg tagaagaagc ttttgaacgt tttggtgaaa agatatgtgc
     7561 ggttcatttg aaagattttc gtgtcgaaca ggaaaaaatc gtgccggtaa atttgggaga
     7621 cggtgtgatc gagtacacaa aaatcaaaga aatcatcatg aagaatcgtc cgtacctgta
     7681 tgtggttctt gaagaaacaa aagatgatgg gattcgttat ggaagaagtc ttcttgaata
     7741 atgtaaagaa gacgttggtt aactaatatt tagaatggag ggggcggggc tagaagatgc
     7801 cacgtctctt cttttttata agagtatata aaagcagctc tttttgatta caaaaaacgt
     7861 ggtataataa aattgtgcat aagtgaacaa aaggaggtgc ggcacatgct ccaaaagaaa
     7921 atcagcggtg aacaagtcaa tacgatggtt tctgatcagt atgaaatcta tcatgtcaaa
     7981 gatgtcgtca gccaaaataa aacgatctat catcatcatg atttctatga gatccatgct
     8041 acattaaagg gagaagcgac tttttatttg aacggacgac aatttacgat caaagcagga
     8101 agtgtgctgc tcatccattc caatgatttg catcgtatcg tccgccaatc ttcagatgta
     8161 ttcgagcgtg tctatatctt tgtcacccct tcttttctag aaagtcgttc cacgccatgg
     8221 tctaatctat cggcttgttt tcaaccaatg ggagagaaga ggagtcgtgt attgcaaata
     8281 gaacaggaag tattgaagca aaaattatca tttatcgacc atcctcctga taaaaaaatt
     8341 tacggtgaag acataaaata tgaacaagct ctggtagaat acttgatttt tctcaatcaa
     8401 gttgtacaaa aagaagagag tgcgcaagaa cagaatgctg tagttcctaa tgagcgtgtg
     8461 gaacaaatgt tacaatatat ctcaaaaaat ttatctcatc cgctttcttt agaggaaatg
     8521 gaaaagcagt tttttgtcag caaataccat atcacacgag aatttaaaaa gtacactgga
     8581 tttacgtttc atcagtatgt aatgaagaaa aagctgatct atgccaagca cttgttgcga
     8641 gaataccgca gctctagtgc tgtatatagt aaaagtggtt tttcttctta tccgcatttt
     8701 ctgaaagcat tcaagagaga gttcggcata acgcctaaag aatttttgaa acgtgataca
     8761 cagaaacagt tggttcatta tgaacatttt gaagatgaac aatgagaatg atcactaaaa
     8821 aataaccgca gtagctgctg ttgtttacat agaagcagaa actgcggtta ttttattttt
     8881 atctatatat ttcaaaatat tttgaaaaaa tgacgtacat attatatgaa tcagctgaat
     8941 ttacgaaagt ctctcggcga tagtcctgtt tttgctttga acaggcggct aaagtaagca
     9001 aaattctcaa tccctatttc ttcggaaatc attcgaaccg taaattctgt ataccgaaga
     9061 aggtctttag cgtaagaaag ttttttgctg atcaaataat cgattggtgg agaaccgata
     9121 aatttggaaa aatctttgct cagctgatat ttattcaata agaattgttg ttctaattga
     9181 tcaagtgtaa tcgtttcttt gaaatgttcg tctaagtatt gcttcagttt gtaaacgtag
     9241 gcgggaatat cctcttcttc gaaatctagc tgatactttt gcaaaatcag ttcattcagc
     9301 aactcgtgga tagctacaga ggactggaaa tcggtacggg cattcgtgcc ttgttgcatg
     9361 tggatcaatt ctgtgatcaa atggtggatc ttgttttctg atggatcccc tgttgaatgg
     9421 aaggtgttat ggccgtcttt tgtgaactcc tgataaaatg attggacgtt ctgaccattc
     9481 aaatggatcc aatccatttc ccatggttct tcgctgatcg tttgataacg ctgatattct
     9541 tggcagtcaa taaaaaataa gtctccagct tttagctgtt gctgattatc attatatgta
     9601 agcgaacctt tgccagacaa agtaaacttt atcaagtaag aaggtaaatg tgctcgttca
     9661 gtatagtaag ggattggtgc tttgaagtaa ccgatttctt ggatataaaa aaataaattc
     9721 ctgcttcttt gtgtaggcgt caagatcact ctttttgagt cttccgacca tgagtggttg
     9781 gctttttccc agtaatccat gtaaacactc ccaacttgtc aagataatgc aattatatac
     9841 caaaatagtg tgaagcaaaa tataagattc tgtattatga tagcattgtt aataaatgat
     9901 aacgctttat taataaagtg ctaatcaaca ataaagtaaa agaggtggag aaatgaatcc
     9961 aacatttgtt gccatcgata tcggtgcatc aagcggacga ctaatgaaaa gtacgaggga
    10021 tgcaaaaggt tctttgatct tggaagaagt acaccggttc aaaaacggct ttcggaacaa
    10081 agacggtcac gatcgctgga agatcgatta tcttatcaaa gagattttga ttggatttga
    10141 aaaattaaag cagacaggga ttgatcgcct ttttgcgggg atcgatacat gggcagtcga
    10201 ttactgtctg attgatgaac aaggggatcg gataaatgat ccgattgctt atcgggacaa
    10261 gcgtaccaat ggagcagtag aacagttttc tgaaatctat tctctagata agttgtatga
    10321 gcagacaggg attcagatcc agcctttcaa taccttgttc caattgtttg ctgaagaaaa
    10381 agaaaatttg gcaaaagcac ataaattgtt actgatacct gattatttag ggtatgtctt
    10441 tactggtaac atggtgacgg agaaaactaa tgcatctact atgcagctgc tgaatgcagg
    10501 gacaaaagaa tgggaaatag aacttcttga aaaaatcggt gtctcgaagg aattatttcc
    10561 accattgaca gagccgggaa cgatactagg agatctgcaa aaagaacaat tttcaaaata
    10621 tgatttgcca gatgtgacct ttatcacagt agcaagtcat gatacggcgt cagctgtatt
    10681 aggaacgcca ggtcaaggag aacgttgggg ttatatcagc agtgggacat ggtcgctttt
    10741 agggattgaa acaaagatcg ccaatgtttc tcgcaatgct ttttctgaaa attatacgaa
    10801 tgaatggggt gcccataaca cggtgcgttt tttgaaaaac atcatgggga tgtggttgat
    10861 ccaggaagtt gcccgaatgc aagagtacga gtacagttat gcggaattgg cagagcttgc
    10921 tgcaaaagaa aaaccgctgc agcaagtgat ggaaatcaat gaccctcgat ttttgaatcc
    10981 cccaaatatg atagaagaga ttcagcaata ctgttttgaa acagagcagc cagtccctgt
    11041 ctcatcggga gctatcgctc gttgtgtgta tgataatctt gctctttgtt acgcacaaga
    11101 gctgatcaaa gtagaacact taactggaac gaaattggaa aagctgcaca tcgtaggggg
    11161 cggatcgaat aatcgtctac tgaatcaatt gacagcagat tatgccggaa tcattgtaga
    11221 agcaggacct agtgaagcca cagcaatcgg gaatgttgcc atgcaaatgc tcagtacagg
    11281 tcagttttcg aatatagaac aagcaagaaa tgtaatcaaa cagtcgtttc catgtgaaac
    11341 tttttaccca gatgaaaata agcaaaacac gatggaatgg tacgtgaata aaatcaaagg
    11401 agtaatcgta tgaacacgat tgaaagaaat tacgaacaag caaaagaaaa atatgcaact
    11461 atcggtgtag atacagatgc tgtactagaa aagatacagg acatcaaaat ttctatgcat
    11521 tgctggcaag gagatgatgt caaaggtttc ttgacaccgg atggcgaatt gaccggtgga
    11581 atcatggcga cagggaattt tccaggagcc gcacgaacac ctgaagagct tagacaagat
    11641 ctggagaagg cttattcgtt gataccgggc aaacacaaat tgaaccttca tgctatctat
    11701 ttggatacag aagaatctgt cgatctaaat gaaattgagc cgaaacattt tgaaaaatgg
    11761 gtagagtggg caaaaaaaga agaaatcggt cttgacttca atccgacttt cttttcgcat
    11821 ccaatgatga aagacggctt tacattggct catccagata aagaagttcg tgaatactgg
    11881 atcgaacacg ggaaaagaag ccgcaaaatc gcggagtact ttgggaaaga aactgggcaa
    11941 acaagtatca ataacttttg ggtacctgat gggatgaaag ataatccgat tgatcgtttt
    12001 accccacggg aacgtttaat ggaatcactc gatgaaattt ttacagaaga gttagatgaa
    12061 cggtatgtac aagatgcagt agaaagcaaa ctatttggtt taggcgctga agcttataca
    12121 gtcggttccc atgaatttta tatgggttac gggttgactc gtgacaaact tgtttgtcta
    12181 gatgctggac attttcatcc aacagaagtg atttccaata aattatcttc attagcttta
    12241 ttcagcaaag gaatcatgtt gcatgtttcc cgtccagtgc gttgggattc agaccatgtg
    12301 gttttgatgg atgatgaatt gcaggaaatc gctaaagaat tagtccgtaa cgaattgttg
    12361 gaaaaaacaa atatcggtct ggatttcttt gatgcaacga tcaaccgtat cgctgcttgg
    12421 gtcatcggta cgagaaatac acaaaaagca ctgctgaaag ctatgctgga accagttgag
    12481 cgattgaaag aaatggagct ggcttttgac tttacttcaa gaatggctta tacggaagaa
    12541 ttgaaagatt tcccgtatgc cgatgtatgg aattatttct gttacaaaaa tcaagttcca
    12601 gttggtttgg attggctgga agaagtccag gaatatcaaa aagacgtgtt ggaattaaga
    12661 aaataggagt gtggctatat tgaaaaaaat agatatttta caagcgcctt atgtgaaaga
    12721 aatgatcgaa acgacgtcga atctttatcg cttgggatgg gatgaaagaa atggcgggaa
    12781 tatttcttat ttactaaaag aagaagagat cacaccgttc ttggatcctg aaaaagtgat
    12841 ccgccgcatc tcgatgattt ttgatgccag ccgtttagca ggatgctatt ttattgtaac
    12901 tggttcagga agatatttta aaaatgtagc gagcgaacct gccgagaatc ttggaatcgt
    12961 tcgagttgct gaagatggca aaacactgga acttttgtgg gggctggaaa acgaatgcct
    13021 tcctacaagc gagttgccaa gtcatttcat gagtcatatc gcccgtttag aagtagaccc
    13081 agataatcgg atcgttatgc attgccatgc tagtcatcta ttagcgatga gttttacgca
    13141 tgaattagac gaacgttcct ttagtcgtac gctatggcaa atgtgtacgg aatgcttagt
    13201 tgtttttcca gaaggaattt ccatcattcc gtggatggtt ccgggaacaa atgagattgg
    13261 ggaagcaaca gctgaaaaaa tgaaagaaac tcgattggtt ttatggccac aacatggaat
    13321 ctacgggtca ggaaaagaca tggatgaagt ctttggtttg atcgagacag cagaaaaggc
    13381 agcagaagtc tatacgtacg tcaaagcgca aggaccaatc ttgcaaacaa tcacggacga
    13441 aaacctgtgg catttagcag atgcgtttgg tgtcactcca aaagcaggtt atttggagga
    13501 agttcatacg aaagcaggtg tctgacatgg tgaaaaaagc tttttgcatg aaagtttacc
    13561 cagaaaaaca agaagaatac aaaaaaagac atgatgaact ttggccagaa atgcgtacag
    13621 cacttcgtga acacggggtc atcgactatt cgatctatct tgatccgagt acaagtttgt
    13681 tatttggtta cttagtgatc gaagatgaaa agttatggga aaaaatggca aatacatcta
    13741 tcaatcaaaa atggtggaag tacatggaag atatcatgga gacaaatcca gatgcctctc
    13801 cagtcagttg ggaattgatg ccagtctttg aactgtagca acaagcaact gggcaaccgg
    13861 ttgcttgggg ttctttcgtt tttattgtga aaaaaaatac aaattaggag gaatagaaaa
    13921 tgagtaatcg aatgatttta aatgaaacat cgtattttgg aaaaggagcg attgagtcga
    13981 tcgtccctga atttcagcag cgaggattcg gcaaagcagc tgtcattact gacaaaggat
    14041 tgatcgagca cggtatagca acaaaagtaa cagaacttct agataaagca gcaatcgctt
    14101 atgctttata cgacgggatc gtacctaatc caacgatcca aaatgtaaaa gatggagtgg
    14161 cttttgttaa agaggcagag gcagactgtt tgatcgcaat cggtggaggt tcgccaatcg
    14221 atacggcaaa agccattggg attattttga cgaatccaga gttttcagac gtcattagtt
    14281 tagaaggtgt tgctgatacg aaaaatccat gtttacctat attagctata ccaacgactt
    14341 ctggaacagc agcagaagta acgatcaact acgtcatcac agatgaagta aatcaccgaa
    14401 aatttgtttg tgttgatcct catgatatcc caatcgtcgc gttcatcgac agcgatatga
    14461 tgatgggaat gccgaaaaaa ttggctgcat caacaggtat ggatgctatg acgcatgcta
    14521 ttgaagggtt tatcacaaaa ggcgcttggg aaatgactga tatgctgcat ttaaaagcaa
    14581 tcgaaatcat cggccattct ttggaagttt ctgtagatgg cgatcaaaat gggcgagaaa
    14641 aaatggcatt aggacagtat attgcgggaa tgggcttctc aaatgtcggt ttaggactgg
    14701 tacacgggat ggctcacccg ttaagtgcat ggtacaacat tcctcatggc gtagcgtgtg
    14761 cagcactttt gccaactgtc atgaaatata acaaagaata tactggagaa aagtaccgtg
    14821 agatcgctct tgttctaggg attaaaggag cagctgaaat gtctttagaa gatgtaagag
    14881 aagcggcttg tggtgagatc gatcggttga gcaaagcggt tggaatccca gaaaccattt
    14941 ctgaattagg tgtaaaagaa gcagatattc cagcaattgc agaagatgct ttgcgagatg
    15001 tatgcacacc aggaaatcca agagaaacga cagtagaaga aatcattgct ttatatcaaa
    15061 gtttgatgta aaaacgaagc ggatcttcaa cattaaattg cctgtaaaga gaaatggtag
    15121 tttatatctg gatatctctt ttaaattgat ggtatttccg ctataatttt tcttataaag
    15181 aaataggaga atattatatg gaaaataaaa agccttatgg aactgtattg atcaaagcct
    15241 ctaaaatact agactattta gcggaaaacc aagatgtctc tttgcagacg atcgcaaagg
    15301 gtgtgggaat gacctcttct acagtcttga aaatactaga tactttgttg atgatcggct
    15361 acgtaaataa aaattcagag aaaaactatc gtttaggtgc aaagcttatt cgctacgcga
    15421 ataaaaacat tgaacaaatc gatttggtag agttgacttt accgttttta gaacagctgc
    15481 agcaaaagat cgatgagact atccacttag gggtattgga caacaatgag atcttgtacg
    15541 tgaacaaact agatccaaaa catcaaacga tccgcatgtc ttcaaaaatc ggaatcaccc
    15601 gaccattata caattctgcg atgggcaaag ccgtattagc agaattcagt gaagagcagt
    15661 acactgatta tcttgaaaag catccgttga tcccttacac agaatatacg atcaccaatg
    15721 cattacggtt gaaaaaggaa atccaaacgg taaaagaaac ccacatcgca tttgacgatg
    15781 aagaaatcga acgtgatatt ttttgtatag gagcctcaat cgtgaaaaac gaacaaatca
    15841 ttggtgcatt tagtgtaagt atgccgaaat atcgtttaac agatgagaca aaagaacaaa
    15901 taatcagtgc cctcaagcaa acaaaaagcg aaatcgagca aagaattcaa aaataatgaa
    15961 aaaagcgttt gcaatttttc ttttctgccg tataatatgg gtatagattt ccaagttata
    16021 aaataaaatt tctaaatagg aaataggtgg agaagatgaa aaaaattgat attttatctc
    16081 gattgaaaaa cgccggagtg attgcggtgg tacgcggaaa aagcaaagaa gaagctttga
    16141 atgcttgcca cgcaatcatc aaaggtggtc taactggtat tgagttgact tttacagtcc
    16201 ctcaagcaga tcaagtaatc aaagaacttt tgtcattcta caaagaccaa ccagaaatag
    16261 tgattggcgc aggcacagta ttagacgctg tcacagctcg cttggctatc ttagctggcg
    16321 cagagtatat tgttagccct tcctttgatc aagaaacggc agagatgtgc aatctgtatc
    16381 aaattcctta cttaccagga tgtatgacta ttaccgagat caaaacagcg ctgaaaagcg
    16441 gggtagatat cgtcaaacta tttcctggaa gcgcttatgg accaagtatc atttctgcct
    16501 tcaaggcgcc gatgcctcaa gtcaatatca tgccaactgg cggtgtgagt ctggacaata
    16561 tgaaagagtg gttcgatgct ggtgtcgtaa cagtcggagt aggtgggaac cttttagcac
    16621 ccgcagctac aggagatttt gacaaagtaa cggaagtcgc gcaacagtat gcagcaaaaa
    16681 tgaaagaaat caagaggtag ctgcttatgg gaaaagtagt gacactcgga gaaatcatgt
    16741 tgcgattgtc cacagagcag ggaacccgta tcgattcaag tgaacgattc gctgcccatt
    16801 atggcggagg ggaagcaaac gtagcaattt ctttagctaa ttacggacat gaagcgattt
    16861 ttgctacaaa agtacctgat aacgcattgg gaaaagcagt caaaaagcac ttgcaatgtt
    16921 atggagtaga tacgaaacag gtattatctg gtggatcaag actaggtact tattatatgg
    16981 aaactggtag tggcgaacgc gccgcctcag tgatctatga tcgtgccgga tcaagttttg
    17041 ctgaaatgga tcatttggaa tggtcgctag aggagttatt ccaaggaata gatatatttc
    17101 atgtttcagg aatcacccca gctttgtcta aaaaatggca aaaaatgacg aaacaggtga
    17161 tagaagctgc aaaaaaagct ggctgcctga tcagcttcga tatcaactat cgtggaaaat
    17221 tatggacaca gcaagaagcc agcgaagtaa tccatcagct tttaccttta gtagatatct
    17281 gctcagctgg aaaaatggat gctctttatt tgttaggtat cgagaaagcg ccagaagcag
    17341 aagaacaacc tctaatttat tattatcaaa aaatgcagga aaagttcccg aatattcagg
    17401 tgttttattc gaccaagcgt accgttcatt cagcaagtga aaatgaattg aaggggacat
    17461 tgtggatgaa ccatgaatat gtggaatccc aagtccatag aatcacccca atcgtggatc
    17521 gagtaggtgg cggagatgct tttgcaggtg gcgtgctcca tgggatttta tccaatatgt
    17581 ctccgcaaga aatcattgat tttgctacgg cagcttctgc cttgaagcat acgatccatg
    17641 gggactgcaa ccaatttagt caagaagaag tcgcacaatt tttagcatgc ggctctggaa
    17701 aaatcattcg atagaaggag tagaagaaaa tgcaagaaat ggaaacacgt tatacacaca
    17761 gtccagaaga tatccgtcat tattcaacgg aacaattgag aaaagaattt ttagtagaaa
    17821 aggtatttga accagggaaa atcagtttga cttatacgca caacgatcga atgatctttg
    17881 gtggagtgac acctactgaa aaagaattag aaatcacatt agacaaagaa ctaggtgttg
    17941 attacttctt agagcgtcgt gaactaggtg tgatcaatat cggtggacca ggattcatcg
    18001 agatcgatgg gcaaaaagaa gaaatgaaaa aacaagacgg atactatatc ggaaaagaaa
    18061 cacgacatgt tgtattttct tctcaagatg ctgaaaaccc agctaaattc tatattagtt
    18121 ctgttccagc tcatcataaa tatccaaatg taaaaatcag tatcgaccaa gtaaaaccaa
    18181 tggagactgg tgaaggcctg acactgaatg aacgtaaaat ctaccaatac atccatccaa
    18241 atgtatgcga aagctgtcaa ttacaaatgg gttatacgat tttagaacca ggaagcgctt
    18301 ggaatacgat gccttgtcat acacatgaac gtcgtatgga agcttatgtc tactttgatt
    18361 atgccaatga agatacacgt gtgttccaca tgatgggcaa accagatgaa acaaaacatt
    18421 tagttgtaga caatgaacaa gccattattt cgccaagctg gtcgatccat tcaggtgtag
    18481 gtacaagcaa ttactcattc atctgggcaa tgtgcggaga aaatatcacc tatacagaca
    18541 tggatatggt gcaaatggat caattaaaat aagcataagg gagagaaaat gatggaattt
    18601 agtatggata tgtttcgttt agatggaaaa gtagcattag tcaccggtgc tgtctatggt
    18661 attggatttg agattgcacg ctctttagct acagcaggag caaaaatcgt atttaataac
    18721 ttgaatcaag aatcagttga tgaaggtata gcgcattata aagaagcagg catcgatgca
    18781 aaaggttatg tctgcgatgt gaccgatgaa gaagcggttc aagcgatggt tcaacagatc
    18841 aaagaagatg taggttcagt tgatattcta gtcaacaatg cagggatcat caaacggaca
    18901 ccgatgatcg aaatggatgc ggcagacttc cgccaagtaa tcgacgtgga tttaaatgcc
    18961 ccattcatcg tttcaaaagc agttattccg gatatgatcg aaaaaggcgg cggtaaaatc
    19021 atcaatatct gctccatgat gagtgaatta ggacgcgaaa cggtcagtgc ttatgctgcg
    19081 gcaaaaggcg gattaaaaat gctgacgaaa aacatcgctt ctgaatacgg tcaatacaat
    19141 atccaatgta atggaattgg accaggttat attgctacac cgcaaactgc tccattacgc
    19201 gaaacacaag aaaacggtga acgtcatcca ttcgatcaat ttatcgttgg acgtacgcca
    19261 gcagcacgct ggggcgagcc aatcgatttg gctggaccat ctgtcttctt ggcttctagc
    19321 gcatctgatt tcgttaacgg ccatgtcttg tatgtggacg gaggcatact tgcctatatc
    19381 ggaaaacaac cttaaaagag ctttagtaca ctgtttagtg gagaggttgt gaaatcagcg
    19441 gattgaacga ataccgaagg acagctgatt aaacatcatt tattcgaaaa aagaggctgg
    19501 gacagaagca tttaactcca agaaataaga aggaattcac gaaaattgct tttcaaattt
    19561 ttgtgaattt cagcttattt ccgaaggagt tgcttttact tccgccgttt gtacgtgttt
    19621 agagcgtgag acaaaagtgt tctttacttt tgtcccacgc tcttttctgt gcgtcttcca
    19681 tacttcacta agtcgatccc tcttgcttcg caccaatcct tcactggtcc ggaaaagatc
    19741 agagattgtt ggtgtagggc cgcggtattc gttgcgccga ccatagtata aagcagacga
    19801 agctcttctt gccattgctt catcagtata atagtttctt ctacgccgtg attcatcaga
    19861 tgcgtcagta cggttcctga agtacccacg gcatttgcgc cgagacaaag ggctttaaat
    19921 atgtcatagg cattgcggat acctccggag gctaggattt ccatagaagt gtctgcttca
    19981 tttgcttcaa gcaatgaaga gactgtcgat tgcccccagt cagctaaata actcagttcc
    20041 cgcttggagc gacgggcgtt ttcgatctgg gtgaagcttg ttccgcttcg accgctgata
    20101 tcaactgtat gaactcctaa agcagctaga tcattgagcg tttctcttgt catgccaaaa
    20161 ccgacttctt ttacgatgag ggggacgtca atggctgttt gagtttcttg aataagtact
    20221 ttccaattgg taaaatcacg gtctccctca ggcataacca actcttgagg tgcattcaaa
    20281 tgaatctgta aggcatctgc gtgaaacaat cggatagctt ctttggctct ttcgacagaa
    20341 gtccctgcac cgatgttggc aatgattttc ccgtgaggat attcttgtcg cataatcgta
    20401 taagtatcgg ctaaagaagg gactttcaag gcagcgctga ctgaaccagt ggcaatcatc
    20461 aaatctgctt ctcttgcgac gattgcaaga tcttggttga ttttttttgt tttttcgctt
    20521 ccgccagtca tcgcattgat ataaaatggg ctgcttagtg taaacccaac tgcctgtgta
    20581 cttagatcga catcagaaac tgctatttgc ggcaaagggt tatggatgat ccgtacgaag
    20641 tcaaattcgt ttttttgttt atcatgaaag gctttagcta gtgaaacatg ttcgtctttt
    20701 cgattcatcg gttttccttt ctttgatcgc tatagacatg taacggcagt ggagtgattt
    20761 ctgctttttc ccatgcactc attaaaggaa gaatgccaga tttctggtca acaattacga
    20821 ttccgcaatc gcccccacct gcaccagaag attttgcggc tccttcatac tgttcagcta
    20881 aattacacaa tttgttcaaa gcaggcgttt cgatgacgac cccagtgatt gcagataaat
    20941 catgcagtaa ttgtcggttt tttcgaatca tctgttggat caacgttaca ttattttctt
    21001 taaacccttt gatcatttcg ttgacacatt ctgtactatt ttttaagaaa agctgataag
    21061 ccaccatttt atcttctctc gaacggtgaa cttgatcgac caaatcagaa gtagaggcag
    21121 ggctacccgt ccaaccaatc aataaacgta aatcttcagg agcaatcaat ggctcaatgg
    21181 atagacctgg ccaatccagg gcaagtaact cactgataga atgctgagtt tcttgttctt
    21241 ggagccaagg atggtcgaag gttgagaaag cgatccagcc accataacag ctagcagcga
    21301 tgtcgccgca ggaaccatta tcttgaactg ctaaattggc tagtgctgca atcttgaaaa
    21361 tctccaactg agataaattc aacgcgtaaa aaacattcaa ggctttgacc gttgcaacgg
    21421 tcacggcacc gctagaaccc aatccatatt tccggccatt tgaactgtct aactcacttg
    21481 ttactttcag atcataaaag gataaaagaa tgtttttttc ttgtgcatac ttttcagtca
    21541 agcgaatagc agcaaggata taatgaaaag gattttcccg aatatctaaa actaattctc
    21601 cgttgcgtct tgtccaacgt acaggcatcc cactatattg tgcagattgg atacttccga
    21661 cttttcgtgc agattctaca gtgactgtca cgaattgatc gactgcagcg ataactgctg
    21721 gatggcctgt ttcaacaact gcatattctc cggcaatata gagtttgcct ggtgcagata
    21781 cttcaatcat aaaaatctcc ctttattcaa taatcgcaat tcctggacca gcatgtgcag
    21841 taattacttg ttctttgcta aataatttgg taaatgtttc ttgtacctca gataaatggc
    21901 tgttttccac taaaactttg acattagggc cagcatccat cgtaaagtag catggaatgc
    21961 cttgctttct caattgtcgc accgcatcca tcgcttttaa gctgtcagga gaccagtaag
    22021 tgaatggagg ctgggcagct aaagtcgttc catgcatttt tagtccgttt ctttccatcg
    22081 tttctccgag aagttggaaa tcttttgttt tgattgcttg tttcaattga tatagatccc
    22141 cttcaacgga atctaaccag ccttgataaa aactggatgt ttcgactgtc cgacgcatcc
    22201 catttctgct ggacacttct tttttctggt cgttgatcaa aacgaaaacc attgctaaat
    22261 cgtcttcgaa agaatcggaa gggactggct tagcgtaaga acttaagtcg tcatggcctt
    22321 tttcccattc gacgaaacca ccgaaaatac ttcggcaagc tgaaccagac ccgcgtcgag
    22381 caaatcttga aagagagaga tcatctaatc caagcttaag agcagtattg caagcgcctg
    22441 ctaaagcagc tagcccgctg gcagaggagg ctaatccagc tgcggtagga acgaaattct
    22501 gactgattac tgaagctttt agtgagaggc cggcttcttt acgaaaaagg tcaagaaact
    22561 gactgacttt ttttgttgct ttttcgtctt gcaaggtgcc atctagataa aattcatcta
    22621 ccatatagct atcagaaaag atgacttctg tctctgtata aaatgcatcc aatgttaacg
    22681 aaaggctgtt gttcattgga aggatgagtt cttcattttt cttaccccaa tatttgatta
    22741 gagcaatgtt ggtatatgcg cgtgctttgc ctttaaacat aggtatgtac tcctaatcct
    22801 tgtatccaag tttcagcagc acccgcatct tcaagtgctt gactgatttc ttgggctttt
    22861 gtttttgttt gtgctaatgc aatcatacag ccaccgcgtc caccgccagt taatttggca
    22921 cccaatgccc cggtatcttt tgctgtttgg atcaatagat taagaaaatc attgctgatt
    22981 gtcagctttt ccagaagtga ttgtgattca tccattgtct gtgccaacgt ttctggtgaa
    23041 ttttcaatga ttgcttgttt tgcttgcttc gtcaagtatc ctaatttttg gatcatttgt
    23101 ccagtttcat gaggctgggt ttcaaagagg tgagcgacat ctttgacggc ttctcttgtt
    23161 tgtcctttga ttcctgtatc agcgacaatc aaaaaagcat cgatgttcaa agaaaagtag
    23221 tcgaaaggat gcccttttgt aaaataaatc ggctgcaagc tgctagtagc ggctgcatcg
    23281 attccactag gattaccgtg ggcgattttt tccgaaagct ggacattttc taatagtatt
    23341 tcacgagaca aaggaaatgc taagtaatca taaaaagcac gagtgactgc tgtggcgact
    23401 gcagcgcttg atcccattcc acgttcagca ggaatcgtgc tttcaatggt cagttgcaag
    23461 tttttttgga tgtcatgctg tttttttaag tgaatgaata attttttgat attttttaat
    23521 gcatgaggag cttcggctaa atttcctgaa tagtaggaag aaaccagttg atcgtccatt
    23581 gcatccagct cttcaaggaa tgcggtgact tttgttgcat agaaaggaaa ggcaatcgct
    23641 ggttctccat aaacaaccgc gtgctcgccc atcaatatga tctttccgct tgattctcct
    23701 tggccatagt ttgccataat ctaactcctt ctcacgtaaa agtgattttt aagcaaaaaa
    23761 taaagcgccc aaaacgagtt gcgctgcttc acgaattttt ttgtccacta agggtctcaa
    23821 aaaacattcc tcctttattt tactaaaacc atctcagaag taaaactaag aatacgtttt
    23881 ctaaagaaaa aacacttttt tcttaagaat tttttgactt tttttcttct ttgactagaa
    23941 aaaaatacaa ttgacactac tagatattgg gggtatattt aaaaaggttg gagttaaaca
    24001 caatatttag tgatgaagtg agctggaggt aaatgagcgt gatcgtttta gcaggtacaa
    24061 ttggtgccgg aaaatcaagt ttaacagaaa tgatggctga acactttgat agtcaggcat
    24121 tttatgaatc gattgatgat aatgaagtct tgcccttatt ttatgcaaac cctgaacagt
    24181 atgctttttt gctgcaaatt tattttttga ataaacgttt tgcaagcatc aaacaagcaa
    24241 tgaaagatga caataatgta ttggaccgtt cgatttatga agattcactg cttttccatc
    24301 taaatgcaga tctaggaaga gcaacagaaa cagaagttcg tgtgtatgat gaactgctgg
    24361 aaaacatgat ggaagaactt ccctatgctg cccataaaaa acatccggat ttattagttc
    24421 atattcgtgt atcttttgat acgatgttgg agcgtatcga aaaacgtggt cgttcgtatg
    24481 aacaattgtc ctttgatcca agtctatacg attattacaa agaattgaac agacgttacg
    24541 atcaatggta tgaagaatac aaagaaagtc caaaaatcca aatcgatgga gaccgctata
    24601 attttgtgga agatcctcaa gcaaaagaag aagtcttgaa aatgatcgaa gaaaaattag
    24661 cagagattcg ccaaaccaaa gtagccattt gatttacagt tgctcaaata aagggtaaac
    24721 ctttatttga gcgacttttt tctttatact ggaaacaaat gtcaggagga tagagtatgc
    24781 gggaaaaaca ctattttaat caagaccgta atttttggat caatgtacag caaaacgatg
    24841 tgctagctgt taaaaactta aaagaagaat atggcattag tgacgagatg ctgacttatt
    24901 ctctagataa aaatgaacgg gcgcgcgtag agtacgattc ttttgatgaa gcgttactgc
    24961 ttgtatcaaa tgttccgcac cagcaaaaag tcgataatca ttatgaaact agtcctatcg
    25021 cttttatttt aaaagaagac ggtttgttta catttaccac gccgaatacc gagtacgtga
    25081 ttcgactaat tcgatcgctt ttggaacgaa tgccagacat gagtgtatac agtttattgt
    25141 ttcgtacatt gtttttgatt tctgattcct tttttccttt aatcgaggaa gtgaatagtg
    25201 aacgtcagcg gcttaatctg aaattaagag aaaaaacaac gaacaagaat ctgctgcaac
    25261 tttcagattt agagatcggt ttggtttact tagttacagg aacaaaacaa aatgtagtac
    25321 ttttagaaca aatcaaggca ttggctattt atcgcaagtt gtcagaaaag gaaaaagaag
    25381 agttggacga tgcgctgatc gaagcacgac aagcagttga aatgacgaac ttagcttcgc
    25441 agattttaga ccagctctct ggcacttata ataatttgct gaataacaac ttgaatgaca
    25501 cgatgaaatt tttgacggtc tggtcgctga tcttgaccgt tccaactatt gtgacaggat
    25561 tcttcggaat gaatctccag ttacccttta cccattccgt tttcggatgg ggaatcgcct
    25621 tgatcatcag tttggtctta tctatttgga tgcttattgc actgtggcgg cggattcgtt
    25681 gatctagtct ttgatctgca aaccaagggc ttgggcgatc acaagtgctt gctcttggtt
    25741 gacgattagt cccgccaaag aatcttgaga taaagcgatt gctgtgaaga aattagtcgt
    25801 aaagtctaat cccttcagag aagttcgaaa ccagttcgaa ccggtcaact gattgtcaga
    25861 caaaaaaagg tttttccaag tgacctcata aaattcgctg tcttctaatt gacaatgatc
    25921 gaaggagaca gctttcaagt ttgtactact aaaggaagcc atcgaagcaa tacaatcagt
    25981 gaaagtacag tctcgaagat aactttcggc aaaattcgta cctgttaatt tacattgatg
    26041 aaacacgact tggtggaaac tgccaccaat ccactccaga ttggaaaaat cacatttttc
    26101 aaaaatgaca ttactgcatt caaaatgacg taaaactgtt ttttgcatcg taagtttttg
    26161 gatatgactc tctcttaata ccatattttt ggcatcgaga tagctttggt cacccccgtt
    26221 gatcagaaga ccagagaaga tctcctcatc ttctaaataa aactctccct ttgtaagaag
    26281 aggaagagaa ggtggaatag gttcgatttt tttcatgtgg gttcacctcg tttttcttta
    26341 gtatagcaaa gaagcgggaa tcactgctag aaagtctgct aatctaatca ttttcagaaa
    26401 aggaagacaa actgtatgaa aaacattgac aaaaagatta gtttttgcta tactatgatg
    26461 gttgagaaat aaaagcagaa gcacccgctt ctcgccttag ttgataatgt cactgggcta
    26521 gatagttttc actggttcta ttaggtgaag tacgcgcggg ttctgtaaga gaactcgttt
    26581 ttttattgcc gtttattcgg taagcttttc tttctctcat aatatttgga ggtgaatgac
    26641 catagcaaag gatatgatgg ttaacgacgg cattcgtgca cgagagttac gattgatcgg
    26701 ttcagatggt gagcaattag gagttaagac aaaagcagaa gcattgaata ttgcagaaca
    26761 agcaaacttg gatcttgtgt tagttgcccc tggtgcgaaa ccaccagttg cgcgaatcat
    26821 ggactacggt aaataccgtt tcgaacaaca aaagaaagac cgcgaagcgc gtaaaaaaca
    26881 aaaagtgatc aatgtaaaag aagttcgctt aagtcctacg atcgacttga atgacttcaa
    26941 tacaaaactt cgtaatgcac gtaagttctt ggaaaagggc gataaagtga aagcttctat
    27001 ccgtttcaaa ggccgtgcca ttacccataa agaaattggt caaaaagtct tgaatcgctt
    27061 agctgaagaa actgcggata ttgcaacagt ggaacaaaaa gcgaaaatgg acggacgcag
    27121 catgttcttg acgctggcac cgaaaaacga cagtaagtaa tttgaatgac taactggctg
    27181 ttggacagcc gatagtcgga taacgaaaga ttttgaggag gaaatatagt catgccaaaa
    27241 caaaaaacac accgcggatc agcaaaacgt ttcaaacgta ctggtaaagg cggattgaaa
    27301 cgcttccgcg cgtttacaag tcaccgtttc cacggcaaaa caaaaaaaca acgccgtcaa
    27361 ttgcgtaaag caagcatggt ttctagtggc gacttcaaac gtattcgcca acaactagca
    27421 aaaatgaaat aagaagtaca aataacagaa tctgaagatt tatttttatt aggaggaatt
    27481 atacatggca cgtgttaaag gtggaacagt aactcgtaaa cgtcgtaaaa gagtgctaaa
    27541 attagcaaaa ggttactacg gttcaaaaca cactttattt aaaacagcaa aagaacaagt
    27601 aatgaattca tacaactacg catatcgcga tcgtcgtcaa aagaaacgcg acttccgtaa
    27661 attgtggatt gctcgtatca acgcagcagc tcgtatgaat ggcttgagct actcaaaatt
    27721 aatgcacggt ttgaaagttg ctgaaatcga catcaaccgt aaaatgttag ctgacttggc
    27781 tgttaacgat gcagcagcat ttactgcatt ggctgaccaa gcaaaagaag ctttggctaa
    27841 ataagctaaa caattataaa gaggaaagaa gataacgaaa agttatgttc tttcctcttt
    27901 ttttatttac aatcctccat caaatgaaac aggacaataa cgtataagtc taaaatagca
    27961 taattaaggt tttttaattg aaaactgaac atttatggtc accctttaat gaaagcgcta
    28021 actacataag ttagaatgag tttgactgat atattagttt gcttatcaga aaaacaaaat
    28081 ggacggagga ataacatgag tgatattatt attggtattt tgttagttat ctcattcttt
    28141 ttcatggtct ggtactgtgt aaaaggctac aacttgatgg tcggctttgc catcatggct
    28201 actgtatgga tgggattagg cgctagtcgg aaacacgttt tcaccaaacc cggcgatgga
    28261 agggcaagga gtaattgatg tgttgacgca tatctatacg acggggccag ctgagtacgc
    28321 caaatcgatc ttggtaaatg tcttctttgg tgcctttttc gggcgtgttc tagtagatag
    28381 cggaatcgca gctaccctga ttcgaaaggt agttgaactt ggaggggaca agccaagaat
    28441 cacgatgagc ttactatgta ttgtaaccgc tgttatattc atgtcgatga caggaatcgg
    28501 accagtgatt tctattgcag ttattgtgtt gccaatcttg atgtcattag gtatttcagt
    28561 accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg ctaatatcgt
    28621 caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg aaagctatac
    28681 ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag ttgtggtact
    28741 aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag caaacgtacc
    28801 agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac cagttttagg
    28861 ggtcgttctt ttagatcttc caatcatctt aggttttatt ctagcaggta tctgggcatt
    28921 gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt ttgcgaaatt
    28981 atttacagat ggcgcagtag atgttgcacc aatggttggt ttcttgatga ccttagcgat
    29041 gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg gagattggat
    29101 accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac taggattttt
    29161 ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg tattagctgt
    29221 taatccaacg atgtcgccag cctttttgtt cccgttattt gcaatcacaa cgattgctcc
    29281 tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata caaaagtaac
    29341 ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggag cgatcttatg
    29401 cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat aaaaacgatt
    29461 agatgaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga tgttggcggt
    29521 acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg aaaatcttca
    29581 gtgaaaacaa cccacgatga tgtccgtgga gtagccgcag gtgtcgttca gtcttttcaa
    29641 aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc acattctacc
    29701 acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt aatcgggatg
    29761 gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa cgatatcgat
    29821 ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa acacttaaat
    29881 gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga ggtcttggtt
    29941 tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta tgaagcagca
    30001 tcggtaaaat cgatccctac aacgatggct tctgacatca caaaattata tggattgaca
    30061 agaagaactc ggacagcagc aatcaatgca tctattttac caaaaatgct agatacggca
    30121 acctctacag aagattccgt acgagaagca ggggtcaatg tttctttgat gattatgcgc
    30181 ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt aaccatgctt
    30241 tccggtccag cagcatcagt catgggctct ttgatgtact tgagagcgtc taatggtgtt
    30301 tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg acgtccagca
    30361 atcgattatt caattgtagg tggccaccca acatatatct cttcattaga tgttcgggtt
    30421 ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat cgatgtcggt
    30481 ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac agaaaaaatc
    30541 aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga ttacgtcaag
    30601 gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc caatgtcctt
    30661 ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg aaaagccatc
    30721 caagcattag ctgattattg tcatacgacg gttgaagaca tcgcagaaca gatcatggaa
    30781 aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta tcacttggag
    30841 aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat tacttacttt
    30901 agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat ttcttctatt
    30961 ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc gccaagtaaa
    31021 gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc aggcgctaca
    31081 ccagaatcga tcgaagtcca cgtagaaatc gatccacaga cttcaaaagt aacggctatc
    31141 gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac aacagaagaa
    31201 gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg cttattggaa
    31261 aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc tggaagtctt
    31321 cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc atgtatgaaa
    31381 acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat ggcagtttat
    31441 caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag agtctctgat
    31501 tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt atctactatg
    31561 gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata agttagaaga
    31621 gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc agtttcggcg
    31681 agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac aacaatcaat
    31741 cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg ccgatgtagg
    31801 agaaatttgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc aaataaacga
    31861 acgaatcact tttgcaactt atgcagaaga tgaagggatt cgattgatga cggagccgtt
    31921 agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc aagctttgat
    31981 tattggacat gaactatttc accacatcga agcttctgtt aagggaattt atacgcaaag
    32041 cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca ttcgtgcatt
    32101 gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt tttcgcctta
    32161 tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag ggatcttaga
    32221 agaaataaaa aaaatagaaa aaagatgtac ggagtatgat ttagattaca aataaagaga
    32281 ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacgatgttc tcctgtcaac
    32341 tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg aaattgttcc
    32401 ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaacggtgt tcaaaagctt
    32461 gcatctgcgg taataagtcc agccaagtta aaaacataag aagctatttt tacttggctg
    32521 ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg tgtgcaatca
    32581 gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat tttgccgttt
    32641 ctttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga tgggtctgtc
    32701 ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct cctcgataat
    32761 catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat caatcattga
    32821 ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg aaatcgtcaa
    32881 acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat cccaaatttc
    32941 tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat caaaaaaagc
    33001 ttttttattt tgagcgatta ctgcctgatc ggtttttcca acttttcccg cgtataacgg
    33061 gctaatgaag cagatcggat atcgattttt gaaacataag tgccggactg tggaatggtt
    33121 tttacaagct cttgattgcg cagttggatc agtgcttctc gaatcggtgt acgcccgata
    33181 gctagttgtt cttctaacac tttatcggag attttacttc caggtgctaa ctcggaataa
    33241 atgatttgtt tacgtataga ttcataagct tgctgttgca aattattgat aaccatttaa
    33301 ccttcctttc tatgcagata taatctatta taacataaat cgcttacaaa tcgtgtgggc
    33361 ataaaaacac agtctgcaaa aaaagccctg ataggcatgc ctattagagc ctcgaaaaga
    33421 aaaatattga atcaatctgg tcgtacctct tgtatcggtt tgacacgacc gccgattctt
    33481 ttagcaaaag cttcggattc ttttttgtct ttgaaaatga gcagattgtc taagtttttt
    33541 tcccgagtgc gacagccagt tttatcgatg taaccgtgca ttactttaac gacatacatg
    33601 gggatcacct gcttttttct tttcattata cgaactactc gacacaatac aagaaaaatg
    33661 cttagacggt ctttattaag aatttacatc atccaaagaa gcgtacgctt ggaataactg
    33721 atctaactcc ggattgactt tgctcagctt cactaatcgt tgcgaatcag aaagtaaaaa
    33781 acagtgttta ctactgccag tagtttttaa ttttttgtct tcagttccca caatttcgta
    33841 gctaaaatcc aaccgtgtcc ccgtatactt ttggatagtt ggatggatgc tcactttttc
    33901 tccgtaatgg atcatttctt tatagctgca atttacttcc agaacgggga tgatgatccc
    33961 agattcttcg atttttttat agggaaaccc tagatgtacc aataaggcta cccgagcctc
    34021 ttcaaaccag cggatataat tgctgtgatg aataatcccc atttgatctg tttcataata
    34081 aaaaggttct cgcacataac ctgtaaattt ctccatgact catgcctcgt tttccattga
    34141 ttttttacaa aaataattca tccatttcgg aagtgcttcg ctgatttgtg tcggcaaaac
    34201 aatatattgt tcttttgcca gctggtctcc aatgaaacta tgaagataaa tagctgctgc
    34261 aatcgtttgg tcattttgag gaaactgggc taaaaatcct gtgatcatcc cagctaaagt
    34321 gtcacccatg ccgcccgttg ccatagcagc agaacctaaa ggattggtgt agaagtgctg
    34381 gtgaccataa atttttgtct catgactttt caaaacgagc acagcaccga tttcctgttg
    34441 cttctttttg ttttctttat cccgttgttc ttgtatcggt agagaactca accgttgcca
    34501 ctccatttga tgaggtgtaa gtacagtttg ttcgggatag ggtagcaaaa gatgattagc
    34561 agcaagtaaa cttaaagcag agccatcaat caccagccat tgttcttttg attggttttc
    34621 tagtacttgt ttgaaacgtt ccaaactctt agaagaagta cccaatccgg gaccaatcaa
    34681 gagtacatct gcttgcttta ttacggaaag aaactggtca gtatccgtcc aaactacaat
    34741 cattgcttct ggcagatgac tgtgaagagc actccgattt ttttcatcag ttactacagt
    34801 cgtgagaccc gctccgctgt gtacggcagc taaagcactc ataatgattg ctccgccata
    34861 ttgttcattg ccgccaatca aaacgatacg tccaaatgtt cctttatgtg aaatttttgg
    34921 acgaggtgtg atgactcttt tcactagttg ttcgtttatc agcatctaaa aacctccttt
    34981 tactcattat agcgtatatt ttttttagag aaaaacagat aagaaaagga attgtcagat
    35041 tttttgaact atttttttct gtaatttgtg gtatcatgaa cacgaagact taaataagtg
    35101 gaggattaac tttatgacaa ttgattggca aaaagaagta gaagcacgta aagaagactt
    35161 gcttgaagac ttgaaaaatc ttttacgtgt caacagcgag cgcgatgact caaaagtaac
    35221 accagatgca ccatttggac ctggacctcg cgacgcattg aaacatatgt tagcttatgg
    35281 cgaacgtgat ggatttaaag taaaaaatgt cgataactat gcagggcata ttgatcttgg
    35341 cgaaggagac gaaacgctag ggatatttgg acacatggat gtcgttcctg caggagatgg
    35401 ctgggacaca gatccttatg aaccagtaat caaggatgga aagatctttg cacgcggatc
    35461 aagcgatgac aaaggtccaa gtatggcagc ttactatgcg atgaagatca ttaaagaact
    35521 tgacttgaaa ctatcaaaaa aagttcgctt cgtagtcggc agcgatgaag aaagcggctg
    35581 gggcgatatg gcttattatt tcgaacatga agaagaacca gattttggtt tctcaccaga
    35641 tgctgaattc ccaatcatca atggtgaaaa aggaaatgtt tctttagctt tacgcttcaa
    35701 aggcgacaat gcaggagatt atgtcttgaa atcttttgtt tccggacttc gcgaaaatat
    35761 ggtgccagga acagcaactg cagcacttca agtaccaagt gcagatgcag ctatcgcgat
    35821 ggaagaagca ttttaccaat tcatcgaagc aaatccagta agcggaacga ttgaagcgga
    35881 caatacgtat gtaaaaatcg aattagttgg taaaggcgca catggtgcaa gcccacaatc
    35941 tggtatcaat gcaggttctt tcttggcatt gttcttagat aactatgaat tcctaggatc
    36001 tgctaaacaa tttatccatg tagcagctgc ttatgtccat gaagattttt atggagaaaa
    36061 actaggagtc gcttatgaag atgaaaaaat gggcaaattg acaatgaatg ctggactatt
    36121 tgcttttgaa gaaaatggta cagaggaagc gaacttcatc aatatgaatt tccgttttcc
    36181 aaaaggtgta acagtagacg gattgcaaag tgacatcgaa caaacagtgg ggcaagaagg
    36241 cgcaacagtt actcgaggtg ctcgcgtaat ggaaccacat tacgtaccaa tggatgatcc
    36301 attggtggct acattattgc aagtctatga agaccacact ggagaaaaag gctacgaaca
    36361 aatcatcggt ggcggaactt acggacgttt gttgaaacgt ggcgttgctt atggagcgat
    36421 gttcccagga tatactgata caatgcatca agcaaacgaa tttatgagtc ttgatgactt
    36481 gttcagagca acagcaatct atgcagatgc catctatcgt ttggcgaaat aattaattaa
    36541 aaagaggatc aagaattgca aattattttt gcagtcttga tccttttttt actttctact
    36601 gtggtattca tgataaacat gatatagatt caattcatat tctttcttag cgttcgtgac
    36661 gactgtatcc aaaatcaacc ctgttactaa tgaaagaagt gctaaagtca tcaatccagt
    36721 acttaaaatc gcagaaggga tgcgtgtaat aaagcttgtc agcatatatt cgcgaatcac
    36781 aggaatcccc gtgaccaatc caaataaaaa gaagaagatg gtccaaatcc caaagaaaag
    36841 caaaggctta taatctttaa acattttaat aatcatcatg atcactttga atccgtcaga
    36901 gaatgtattc aattttgatt cgctgccttc aggacgatca cgataatcga ttgggatttc
    36961 aacgaacttg aattttttat ctaaagcatg gatcgtcaat tccgtttcga tttgaaaacc
    37021 agaactcata ataggaaaac ttttgacaaa gatacgattg aatcctcgat agccggtcat
    37081 gacatcaaga atttttgttt tatacattct agtaattgta tttctaacaa ggttatttcc
    37141 aaaatcgtgg aaaggtctct tattctcatc aaagtaggtt ccatttgata ggcgatcacc
    37201 aatgaccata tctgcttcac cagaacgtaa tttctcgagc aaaccatgta cagcttctgc
    37261 aggataagta tcatcgccat ctaccattaa ataatagtcg gcatcgatat caaagaacat
    37321 ttggcggatc acatttcctt ttccttgacg aggttctttt tttacgattg ctccaccttg
    37381 aacggccaat tcgtatgttc gatcggtcga attattatca tagacataaa tatctgcttc
    37441 tggtaattct cgtttaaagt ctgcaatgac tgttgaaatt gttgcttcct cattgtaaca
    37501 aggaatcaga acagcaattt tttcttgttg ttccattttt cactctcctt aactatagaa
    37561 aacaaaagct aaattaaaaa tacctcataa tcaaaggaaa tgctagtttt tcccgctaaa
    37621 tatcatttat ttaaaaagaa aatactggaa tatatgtttg gaaagctcta tctaaaaaac
    37681 cacccactac aaaagaagga catgatacct ctcttttgaa tagtgggtgc gtattcgttc
    37741 tctcactttt ttgacgtatt aatctgttgc accttttttt cttgaaattt ctaatacggt
    37801 tcctgtatga gcatctgcta aaaattcata ataaacagtt tcgccatctt ctattcgaga
    37861 aagacctccc cgataagcac tcgaccgaac ggcgaatttc ctaataggtt ccttttcaaa
    37921 agagatccaa gaaccttcga ttgcaccttc ttttagaaaa gatgacttga tattttcaag
    37981 tacttggtct gctgacaata cttttttgcg atgataccaa atcgttgaag ctaccccgct
    38041 caataatcct agaccgattc caactgctaa cccgccttta aaatagctta gttcgctttc
    38101 ttcatacatg tggacatacc tccttcttct cacttgttac tccttgtgct tattttacca
    38161 cactctcata ttttctttga aataaataac cgctaccaga aaaaataagc tataataaat
    38221 acgatcggtc tgcagaaaaa atcatatttt atccgcagat caatataagt ctgagaggag
    38281 tttagtctga aatttagacg aatagcatat ggaagaaaaa acatttcaac gaatcaaaga
    38341 gttaacagaa ttacaaggaa caagcggttt tgaacaagat gttcgcgctt atatggaaag
    38401 tcatatggaa ccgctggtag atgagttaca gttagatggt ttgggcggca tttttggtct
    38461 gcgccatcat gaagaagcgg atgcaccccg tgtaatggtc gcagcacata tggatgaagt
    38521 cggattcatg ctgacacaaa tccaagaaaa cgggcttttt aaagtcgtac ctctaggcgg
    38581 ctggaatcct tacgttgttt ctgctcagcg ttttacactt aaaacctcta ctggtaagaa
    38641 ttatccatgt atttcttctt ccgttccccc acatttattg cgaggaacaa gcggacaaaa
    38701 atcagtagaa gtaaccgata ttttgttcga tgctgggttt gaatcaagag aagaggcaat
    38761 gagttacggt gtccttccag gagacacaat cgttccttac gctgaaacga tcaaaacagc
    38821 caacggaaag aatattatca gtaaatcatg ggacaaccgc tatggctgta caatggtatt
    38881 agaagcttta gaagcgttgc aaaatgaaac attaggtcat acattgattg caggcgcgaa
    38941 tgtccaggaa gaagtaggct tgcgtggttc taaagcttct gtcaataaat tcaagccaga
    39001 tctgttcttt gcagtagact gctctgcagc agatgataca gtgacgaaaa atggcacatt
    39061 cggacattta ggagaaggta cattgatgcg tatccaagat ccaggtttga tcatgcttcc
    39121 tcgtttgcgc gagtacttgc tggatatcgc tgaaacaaac aatatccctt atcaatactt
    39181 tgtttcaaaa ggcggtacag atgcaggtgc tgctcataca caaaacgaag gaatcccaag
    39241 tacagtgatt ggcgtagtgg gacgttatat ccatacgcat caaacgatgt tcagtattcg
    39301 cgattttgaa gctgcacgag aaatgttgat tcaaacactg aaaggtttgg ataaatcaac
    39361 agtgaatacg atcgtatacg gaaaataatg cgatagtgaa actataaaat ctggcaaaag
    39421 attgcttttt gccagatttt ttttataaaa agaggatcaa tgtttgttag ttcgaaagaa
    39481 aggtgtataa tttaattgaa aaatacataa acagaaagta gaggacaaag aatgattatc
    39541 ccaaatagtt tagaagaatt agcaggctac gtagaaactg gaaagagtgt atttttcttt
    39601 actgccggct ggtgcggaga ctgccgtttt atcaaaccgc aaatgcctga aattgaaaat
    39661 gacttttctg attggcaatt tattgaagta gaccgtgaca agtacataga tgtagccgct
    39721 gaatggaaca tttttggtat cccaagtttt gtcgtgatcc aagacggaaa agaattaggt
    39781 cgtctagtga ataaagatcg taaaacaaaa caggaaatcg aatcgttcct agaaagtgta
    39841 acaaaaggct gacatctgtt aggaggggtc aagatgaatc aagaatataa gaatatttta
    39901 gtaggtatcg acggtagtga acaagcactt gctgctttca aaaaagcggt agaagtggct
    39961 cgccgtaata atgggaaagt atatgtagca aacgtaatcg atcagcaatt ttataacttt
    40021 atgggctatg cacctattga tcaaaatcta gtcgatcagc aaactgaaac agccaaggaa
    40081 atgatcgaag aatgtaaaga atatgggaaa tctgttgatt acacaaatat agaaggaatt
    40141 attgcatatg gttctgttcg tgaatccatg gcagtcaaat tgccaaaaaa atatgagatc
    40201 gatctaatca tggttgggca gtcaggtcta aatgcagtcg aacgctttat gacaggaagt
    40261 gtagccagct acgtgatacg tcattcacct tgtgatgtct tgatcgtttc tgacgaagaa
    40321 gaacagccaa gtaattaagc aagtggaact tgtacgacct ttttaatcaa ttaactaaaa
    40381 cagtaaaggg actgtgacaa aagtcttgtc acagtccctt gttacgaata aatggtgttc
    40441 cagaagaggc ttcttcggaa ataaagcatg aaaaaaattt catgcagtga atgcaatttt
    40501 ttgttaagat aaatctcagc aaaggataat ggaggaaaga acatgatttt tgcttataac
    40561 aaagcacacg tcggagacac cttgatggtt attatagccg acgataaagg aacagaaaac
    40621 actgttgaac gcaaatggaa tgttgctcgg atcaaagatg aacaaggtca agttgttgct
    40681 tggaactttt tccatatctc cgatcatcta acaatcgaag ggaacggcca agtaagctta
    40741 acagatgagg aattagcgaa attgaatcga ttgatcaaag aagcaggatt cgaagaacag
    40801 cttgaagctg atcatgaacc gaagatcgtt gtcgggtacg taaaaacatg cgtcccacat
    40861 cctgattctg accatttatc gattactgag acagaagtag acaatggtac agtattgcaa
    40921 atcgtttgcg gtgcacccaa tatcgaagct ggacaaaaag ttgtcgttgc aaaaccagga
    40981 gctatgatgc cagatggaat gatgatctgg ccaggaactt tgcgaggggt agatagctat
    41041 ggaatgatct gttccgctcg tgaattgcat ttgccaaatg ctccagcaaa aaaaggaatc
    41101 ttagtattgc ctgaggatgc cgtagtcgga gaagcatttc caaaataaag aggttgtgac
    41161 aagtctttgt cacaacctct tttttattaa ttttcactat tttgattttg ttttaatgcc
    41221 gattgatcga tcgtcaattc aacagtagtt gttttttctt tcgagccttc atagtaagtg
    41281 attttgacag aatctcccac ttttttctta tacaaagcag attgaagttc tacaccagaa
    41341 gaaacttctt tgtcatcgat cttagtaatg acgtcgtatt gtttcaatcc agctttttca
    41401 gccggtgtag ctgtttggac atttgtcacg atgacaccgt tagttacaga tgaaggaatc
    41461 ttcaagattt gttcttgttg ctgagtagaa acggcagata agtcgaccat tgtgatacct
    41521 agagctggac gtgtcacttt tccgtctttt tccagttgat tgatgatatt cactacatcg
    41581 ttacttggaa tagcaaatcc cattccttct acgcttacat tagaagtaga ttcagaagta
    41641 cttgcgatct tacttgagtt gataccgata acttgtcctt cgatattaac taaaggacca
    41701 ccagaatttc cagggttgat tgctgcatct gtttggatcg cattgatatt gactgtttcg
    41761 ttcgattcat tcgtacttgt cacttgtcgg ttcaaggaag aaatgattcc tgaagtgaca
    41821 gaatttgcat attcagatcc tagtggggaa ccaatcgcaa tcgcaggctc accaaccttc
    41881 agagcacttg agtcaccaaa agaggcaact gtttcgactt tgtctgaatt gatcttcaac
    41941 accgctaaat ctgaataagc atctgttcca actaattcag cttttacctt cgtaccgtct
    42001 ttcatcaaga cttcaagacc ttgctggcca tctactacgt gattattcgt gactacataa
    42061 gcagtattcc cgtctttttt gtagatcacg ccgcttcctt cactataagc ttccaaatta
    42121 ctatcatctg agctgctact ttcttcttgc tgcccgaata gtccgccaaa accgcttgat
    42181 tggttttgac tttgtaagtt gataacagaa acgacagcgt cttgaacttt atctaccgct
    42241 ttggtgatat cagaatctac attgactttg acattttcca caactgtttc accggcagaa
    42301 ttctgattgc cgcttgtagc agtagaacta ttgttgccag tgcccatcgc tgcataaaaa
    42361 atgccagctg tcagtagtcc tccaacgatc cctccaacaa gccccagacc taacttacgc
    42421 cagaggctat tatttttact ttttttcatc tttggtgtca cattttttct atccatgtgt
    42481 tcctcctcca attacattca tttatctact gttagtatag tcttatttgt tgactttagt
    42541 ctactttgag actgtgaact ttttatgaaa aactttagga aaaatcattg ttttcagatg
    42601 aaaatatttg attttctttt tccacagata ctgtgtaaaa ctacgcggat aggattggaa
    42661 aaataaggga taaaacatat ccacagcctg tgtataaagt ggataaattc ttataaaacg
    42721 tatgtttgcc taatgaatgt gatgaaataa ggtaaaataa cactgttttc tgtggataaa
    42781 cctgtggatg ttgtgcataa ctgttgggga aatcttttta acaaaaatag ccaaaataaa
    42841 catatagacg aaaaaattga ttataataaa caaagtgagc atgaagacca aaggagagaa
    42901 aacatgaata tcaaaattat ctcagtagga aaattaaaag aaaaatacct gatccaaggt
    42961 atcaatgagt atgtcaaacg gctgaatgcc tatgcaaaaa tcgaattgat cgaagttcct
    43021 gacgaaaaag ccccggagaa tttaagcgaa gcgcaaatga gacaagtaaa agaaaaagaa
    43081 ggggaacgga tcttagcgaa aatcaaagaa caagaatacg tctatgcctt agcaattgaa
    43141 gggaaaaatc ctacaagtga atcttttgct aaacaaatcg accaattagg tatccaagga
    43201 aaaagccacc ttgtttttgt tatcggcggc tctttaggac tcagcgaagc cgtcatgaaa
    43261 agaagcaatg ctcagatctc ttttggaaaa atgacgtatc cacatcaatt gatgcgtctg
    43321 atccttgtcg agcaaatcta ccgtgccttc cggatcaatg cgggggcgcc ttatcataag
    43381 tgatgcggtt tttatcattg atcctaaaaa tcttagcaag acaaaaagta cgtaagaaag
    43441 taaagactaa atacttcgga ggaacaaatg aataacaatg ataggttatt gcgattgcgt
    43501 tatgcgattg atttgaaaga tacggatttg attaaagctt ttgagctagg cggtgtacca
    43561 ctgactaaag aagaagctca ggcggtactg accaaagtac aggataagaa caaagataat
    43621 gcagaaaata atgtgtatga aaaaaccatc aacaaccaag tttttgacgc attcctaaat
    43681 ggcctgattc tcttggcgcg tggtccgcaa aaagataagc cgatagtaga cacgccgcaa
    43741 aaaagcaagg aaatcaaata tatcaacaat gtgttgctaa aaaaattaaa aatcgccttg
    43801 tctatgacca ctgatgatat tttagacgtt tttgctgagg cagaaatcta tccatcaaaa
    43861 ggcgaaatcg gggcattttt gagaaaagaa ggccaacgaa attttaagcc ttgcggagat
    43921 aaatatatgc gtaattttct caaggggtta ggaatttata atcggagaaa agtataaaga
    43981 aatttcatga gaaatcaaaa caatggttgt tttgatgaga gctagttttt gtatgagatt
    44041 aaaatattat cttaatcgag gagctggatt ggttttatga atgatgaata taagaatgat
    44101 gaagataaga tgctttttga agagatagag aatcgatgta ggctcaattt tgagcttcgg
    44161 ggaaagatgt ctttaataca acaaaaaaag tatttagcga ataaatcaga gtttactctg
    44221 ggacatgttg aaaaattaat ctcggattgg attagtagta gaagcgaatt tacaaaaata
    44281 aaacagccga ttaaatttga catgaaaaaa cttttgttaa ataagagtga gataggtaat
    44341 agagatcaat atattagagc taaagggcaa gaaataattg attcattagg tgaaatgagg
    44401 tcatacaatt atttgtatgt aacacataga gctgatggaa tggtcattac tgtggggaaa
    44461 tcttcttcta atgatatttt tttagatgga gatctttttt atcaactcaa tacaaatcac
    44521 ttgtctggca ctgaaaatat aattttaagg acggaatatg gcaatgaaat atttgcaaaa
    44581 tatgatgaga ttttaaaaaa ttatttggac tgggcttgga taattccggt tgagtcagga
    44641 gatgctaaga aactggagag attattgggc gatgaactaa ttaataaaaa agtaccaatt
    44701 ttaaattatt attcccatag acaataaaag gctatttttc atgataatac tagttataac
    44761 tgtaaaaatg gaagaaaatc tgggaaagaa gtttttaaat aagtgtattg ttcgatttta
    44821 ataaataata agcaatacca tccgtctgtg ttgcgcaaca tcgtactaca atgaatattt
    44881 tttcacaaaa agaaaatcat ccatcgaatg aatggaaggt tttagtatac acgaggttaa
    44941 tgccccctct tttataatca gaggagtgag gttttttcta tgaatgtttc tattttctta
    45001 ttgctagtct agtttctctt acgatgaaat tgggattcta ttccagtttt tattgatttg
    45061 ctgataaaat aacttgaatg gtggatataa acatgataaa taagagaaga ataacaaaac
    45121 aaggttgtga aatgattctc aaatgaatat aatagaaaga aaaaggagga agaatcaatg
    45181 aaaatagcaa ttgcaggcgc tggcgcaatg ggaagtcgct ttgggttaat gcttcaccaa
    45241 agtgggaacg aagtattatt aatcgatggc tgggcagaac atgtccaaca aatcaaagag
    45301 catggattac aagcaaattt taatggtaaa gaggtagaag caaaactacc aatcgttctt
    45361 caatccgaag tagaaaaaga agatcaagtt gatctgatta ttctatttac caaagcgatg
    45421 cagctggaaa aaatgctgca ggatatccaa tcattaatca aaaaagatac agaggtctta
    45481 tgtctattaa atggtatcgg gcatgaagat attattgaga aatttgtacc aatggaaaat
    45541 atctatattg gaaataccat gtggacggca ggtcttgaag gtcctggtca ggtcaaatta
    45601 tttggaagtg gttcagtaga attacaaaat ttaggtgatg gaaaagaagc agctgcaaaa
    45661 aaattagcag acaaattgtc tgaatcagga ttaaatgctc atttttctga caatattcac
    45721 tattctattt atcgcaaagc atgtgtgaac ggaacaatga acggactatg cacaatctta
    45781 gacgttaata tggctgagct aggaaaaaca tcgactgctc ataaaatggt ggcgacgatt
    45841 gtcaatgagt ttgccaaagt agcagcagta gagaagattg aactagatgt cccagaagtc
    45901 attgcacatt gtgaatcttg ttttgacccg gaaacaattg ggttacatta tccttcaatg
    45961 tatcaagact tgattaagaa ccatcgatta acagaaatcg attatatcaa tggcgcaatt
    46021 tctagaaaag ggaagaaata tggtgttgcg acgccttatt gtgatttctt gactgagctt
    46081 gtccatgcaa aagaagatag tttgaacgta aaataaagga gagattgaat ggaaacttca
    46141 caaaaaatat caccgaaaat ttttctgaat aaagtcctcg ctggtacagc aacaggaatc
    46201 attattggat tgattcctaa tgcagtatta ggtgccattt taaaatattt tagtgcgtat
    46261 ccctttgcgg taacgatcgc acagttagca gttatttttc aactagcaac acctttgatc
    46321 attggtggtt tgattgcctt acaatttgga tttgatccga tgagaatgat ggttgtagcc
    46381 ggagcttctt ttgttggttc tggtgtagtc aaattcacac ctgatttggg tgaaacgggt
    46441 gtttacgttg gtgctggtac aggcgatatt attaatacga tgctgacagc atcgattgct
    46501 gtcgggctga ttttactgat tggaaatagt tttgggtcag tgtcgattgt gttaacaccg
    46561 attgttgtag gtgtaggtgc aggtttactt ggtttttatt tattcccttt tgtaacagca
    46621 attacttctg caattggatc attgattaat aacttcacta ccttacaacc gctgttaatg
    46681 tctatcttga ttggttgttc ctttgccttt ttgattatct ctcctatttc aacagtagca
    46741 atcggaatgg caatccaact agatggtgtt tctgctggtg cggctgcgat gggcgtagct
    46801 gcaaccactt ttgttttagt agtgaactct tggaaggtta ataagtcagg tgtgacaatt
    46861 gcgattgctt taggcgctat gaagatgatg atgcctaatc tatttagaaa acctgtgatt
    46921 cttattcctt gtttagttag tgcagtgatt acagctattc ctgtcgctct attttctatt
    46981 tcaggtacgc ctgcttctgc tggtttcggc gtggtcggac ttgttggtcc gttggcttct
    47041 ttagatgcag ggctaaatgg ctttcttgtt gttctttgtt ggttagtcat ccctgttttt
    47101 gcggcactaa ttactcaatt tttatgcgag aaagtattta aactgtatga tcgagaagaa
    47161 gtcttcaaat ttttaggcta gtagatttta ctaagaaatt ttcaatcaat ggatgcgtaa
    47221 gtgagatgtc aacaacatct gacttacgtt tttttgcctt tttgagtagg agattgatgc
    47281 tgacaactga actcttcagt gccattcgat tttttaaaat gtagaagaaa ctcaccttta
    47341 tgttattgat tgttcaaaag gcaactagaa taaaaatatg tgttaaaatg agaaaaaatt
    47401 tgattgttgg atgtatcgaa taatcactaa aaagtaggag aagaaaatga tttttttgca
    47461 aaaatatggt ttttattttt tattattagg tgtgattagt gatttatcga caccgtatat
    47521 ccttggcctt ttttatccca aactgaatca aatgactacc gtaattagtg tgtttggtga
    47581 cgtagatagt ccagtcagac gtgctttctt ggtctggtca gttgtatctg gacttttttt
    47641 tgttctttcg ttgcctgcgt tgtatcacct atttattgga acatcaaaaa cacttgcaat
    47701 acttgctgtt gcaacagttg gtttatatgg gataggtgat tgtattttta ctgggttatt
    47761 cagtatcaat acgaatgaaa gctcttggaa tctatcgact tggatccata atataggttc
    47821 tgggctaggc tatgcaggct ttctactttt cccattgtta cttgttctgc tttatcgtca
    47881 aagtggtcaa ggtacgctta gccattttta tcttgtttta acagttatta gtttactaat
    47941 tgcaggtctt tacggattag cacggattcc gtcgattagt cagtttgcct tctttaagca
    48001 attgggcttc tttcaacgct taagtttttt ctttaactat ttgccgatga tttgtttaag
    48061 tttttttcaa ctacgaaagt agaaaaagca gtgtgaagct gattaagtaa aagaatttct
    48121 ctatgggtaa ccattcgtgt ggatgtgttc gactaagaat agagatgagg agagcgaaaa
    48181 gcaagttagt cttaacttgt tatgcgttgt gctaaatttc aggtagtcat tttttgaatg
    48241 aataagaaga aaacttgaaa gagggtgact tcatgttaga tgtggagcag atggaaatag
    48301 acctttataa tattatttta aatcgaaata caagagaatg ggaaagaaca caatttgaag
    48361 aggcaaaaga agacctagca aaaatgtcga taaagcaggt gatagaaaaa ctagaggtca
    48421 acttgcgtcc gctagcacta cgagataatt tgacaccaga tgcgatggat ttttatttaa
    48481 gaatcacagg ggagtcagcg agtgcaaagg cttatgatta tgccaaacat aagataactt
    48541 cacccttata ccaagaacgg gcgatttttg ccggtggctg tttctggtgt atggttgagc
    48601 cttttgaaac aaaaccaggt gtaatctcag tgttatctgg ttatacaggt ggagagacca
    48661 aaaaaccaaa ttacgatcaa gtcagtggtg gatatactgg gcatgttgaa gctgttgaga
    48721 tcatatttga tacacgtcaa ataacctatg aagagctgtt ggagatttat tggcaaattt
    48781 cagaccctac agatgccttt ggtcaatttc aagatcgggg gaaacaatat cgttcaattc
    48841 tatttgttgt taatgaaaag caaaggcaat tggctgaaaa atcaagagaa caactgattc
    48901 aatctaaccg atttagccgt cctatcgtta cagagattcg ccaagcaaag actttttggc
    48961 cagctgaaaa tcatcatcaa caattttatc agaagcaacc taaaagatat aaaaagatca
    49021 agcattcgca tcagcttcat ttattttttc agcgacatag atagaggaag gttgtggcgc
    49081 aaagcgttca gctccgacaa aataatgagc aactgacaaa aatagctttt catatttttg
    49141 gacagttatg aattatttcg aggagttgct ttgagaacac cgaggaaaag gttgtggcgc
    49201 aaagcattca gcttcaagtc gcaaggaaac aggaggtatg acaagtcttt tgtcacaact
    49261 cctgtttttt tactagcctt tatttccatg tgaaagagaa ttcgaattgt agaatcttga
    49321 tttttctatg gaattttgta gagaatcatc ttgataatta atagacacct aatcgaattc
    49381 cacattaatg atgaactaaa ttccgtataa aagcgcaaac aataactata a
//
LOCUS       DAZKPE010000013        46819 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000013 DAZKPE010000000
VERSION     DAZKPE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.013"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            183..1229
                     /locus_tag="ACG930_000856"
     CDS             183..1229
                     /locus_tag="ACG930_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518032.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            1231..2490
                     /locus_tag="ACG930_000857"
     CDS             1231..2490
                     /locus_tag="ACG930_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFQ0518033.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            2496..3077
                     /locus_tag="ACG930_000858"
     CDS             2496..3077
                     /locus_tag="ACG930_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFQ0518034.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(3159..4034)
                     /locus_tag="ACG930_000859"
     CDS             complement(3159..4034)
                     /locus_tag="ACG930_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0518035.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            4182..4514
                     /locus_tag="ACG930_000860"
     CDS             4182..4514
                     /locus_tag="ACG930_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFQ0518036.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            4626..5834
                     /locus_tag="ACG930_000861"
     CDS             4626..5834
                     /locus_tag="ACG930_000861"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFQ0518037.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            5988..6443
                     /locus_tag="ACG930_000862"
     CDS             5988..6443
                     /locus_tag="ACG930_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518038.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            6805..7080
                     /locus_tag="ACG930_000863"
     CDS             6805..7080
                     /locus_tag="ACG930_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518039.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            7093..9171
                     /locus_tag="ACG930_000864"
     CDS             7093..9171
                     /locus_tag="ACG930_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFQ0518040.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            9334..11217
                     /locus_tag="ACG930_000865"
     CDS             9334..11217
                     /locus_tag="ACG930_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0518041.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            11229..12176
                     /locus_tag="ACG930_000866"
     CDS             11229..12176
                     /locus_tag="ACG930_000866"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFQ0518042.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            12196..12723
                     /locus_tag="ACG930_000867"
     CDS             12196..12723
                     /locus_tag="ACG930_000867"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFQ0518043.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(12786..13439)
                     /locus_tag="ACG930_000868"
     CDS             complement(12786..13439)
                     /locus_tag="ACG930_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFQ0518044.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            13571..14413
                     /locus_tag="ACG930_000869"
     CDS             13571..14413
                     /locus_tag="ACG930_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0518045.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            14571..15467
                     /locus_tag="ACG930_000870"
     CDS             14571..15467
                     /locus_tag="ACG930_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0518046.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            15470..16183
                     /locus_tag="ACG930_000871"
     CDS             15470..16183
                     /locus_tag="ACG930_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFQ0518047.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            16203..16721
                     /gene="msrA"
                     /locus_tag="ACG930_000872"
     CDS             16203..16721
                     /gene="msrA"
                     /locus_tag="ACG930_000872"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0518048.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            16718..16945
                     /locus_tag="ACG930_000873"
     CDS             16718..16945
                     /locus_tag="ACG930_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFQ0518049.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            17097..17648
                     /gene="lepB"
                     /locus_tag="ACG930_000874"
     CDS             17097..17648
                     /gene="lepB"
                     /locus_tag="ACG930_000874"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFQ0518050.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(17731..18273)
                     /locus_tag="ACG930_000875"
     CDS             complement(17731..18273)
                     /locus_tag="ACG930_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFQ0518051.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(18510..18908)
                     /locus_tag="ACG930_000876"
     CDS             complement(18510..18908)
                     /locus_tag="ACG930_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0518052.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            19168..20028
                     /gene="ylqF"
                     /locus_tag="ACG930_000877"
     CDS             19168..20028
                     /gene="ylqF"
                     /locus_tag="ACG930_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFQ0518053.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            20021..20788
                     /locus_tag="ACG930_000878"
     CDS             20021..20788
                     /locus_tag="ACG930_000878"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFQ0518054.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            20844..21701
                     /gene="dprA"
                     /locus_tag="ACG930_000879"
     CDS             20844..21701
                     /gene="dprA"
                     /locus_tag="ACG930_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFQ0518055.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            21823..23901
                     /gene="topA"
                     /locus_tag="ACG930_000880"
     CDS             21823..23901
                     /gene="topA"
                     /locus_tag="ACG930_000880"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFQ0518056.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            23870..25246
                     /gene="trmFO"
                     /locus_tag="ACG930_000881"
     CDS             23870..25246
                     /gene="trmFO"
                     /locus_tag="ACG930_000881"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFQ0518057.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            25444..26349
                     /gene="xerC"
                     /locus_tag="ACG930_000882"
     CDS             25444..26349
                     /gene="xerC"
                     /locus_tag="ACG930_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFQ0518058.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            26386..26934
                     /gene="hslV"
                     /locus_tag="ACG930_000883"
     CDS             26386..26934
                     /gene="hslV"
                     /locus_tag="ACG930_000883"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFQ0518059.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            26948..28348
                     /gene="hslU"
                     /locus_tag="ACG930_000884"
     CDS             26948..28348
                     /gene="hslU"
                     /locus_tag="ACG930_000884"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFQ0518060.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            28366..29157
                     /gene="codY"
                     /locus_tag="ACG930_000885"
     CDS             28366..29157
                     /gene="codY"
                     /locus_tag="ACG930_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFQ0518061.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            29239..30114
                     /locus_tag="ACG930_000886"
     CDS             29239..30114
                     /locus_tag="ACG930_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFQ0518062.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLNDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(30246..30884)
                     /gene="plsY"
                     /locus_tag="ACG930_000887"
     CDS             complement(30246..30884)
                     /gene="plsY"
                     /locus_tag="ACG930_000887"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFQ0518063.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            31011..31445
                     /locus_tag="ACG930_000888"
     CDS             31011..31445
                     /locus_tag="ACG930_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFQ0518064.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            31611..33656
                     /gene="parE"
                     /locus_tag="ACG930_000889"
     CDS             31611..33656
                     /gene="parE"
                     /locus_tag="ACG930_000889"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFQ0518065.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            33668..36118
                     /gene="parC"
                     /locus_tag="ACG930_000890"
     CDS             33668..36118
                     /gene="parC"
                     /locus_tag="ACG930_000890"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFQ0518066.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            36395..38626
                     /gene="pflB"
                     /locus_tag="ACG930_000891"
     CDS             36395..38626
                     /gene="pflB"
                     /locus_tag="ACG930_000891"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFQ0518067.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            38870..39631
                     /gene="pflA"
                     /locus_tag="ACG930_000892"
     CDS             38870..39631
                     /gene="pflA"
                     /locus_tag="ACG930_000892"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFQ0518068.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            39716..40642
                     /locus_tag="ACG930_000893"
     CDS             39716..40642
                     /locus_tag="ACG930_000893"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFQ0518069.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            40824..41717
                     /locus_tag="ACG930_000894"
     CDS             40824..41717
                     /locus_tag="ACG930_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFQ0518070.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            41851..41976
                     /locus_tag="ACG930_000895"
     CDS             41851..41976
                     /locus_tag="ACG930_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFQ0518071.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(42110..42742)
                     /locus_tag="ACG930_000896"
     CDS             complement(42110..42742)
                     /locus_tag="ACG930_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518072.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(42890..43432)
                     /locus_tag="ACG930_000897"
     CDS             complement(42890..43432)
                     /locus_tag="ACG930_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFQ0518073.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            43567..43956
                     /locus_tag="ACG930_000898"
     CDS             43567..43956
                     /locus_tag="ACG930_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518074.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            43960..44724
                     /locus_tag="ACG930_000899"
     CDS             43960..44724
                     /locus_tag="ACG930_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0518075.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            44853..45800
                     /locus_tag="ACG930_000900"
     CDS             44853..45800
                     /locus_tag="ACG930_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0518076.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            45930..46670
                     /locus_tag="ACG930_000901"
     CDS             45930..46670
                     /locus_tag="ACG930_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518077.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT        16311 a         8004 c         9785 g        12719 t
ORIGIN      
        1 tttcctagca gaaaaggaat aaataagaga cagagattcc gaatccgtat gtcatacata
       61 gaaaacacat gtattttatt taatttttat ttatttgcaa gttatgaggt gagctttgct
      121 cttatctttt ctagaatttg cttactaatg gtaaaataaa aataagaaga ggagggatgc
      181 gtatggaact tgattatcaa gtagaagatg cgttgacgaa agtgttttac ggagaaacgc
      241 tagtcagtca gctaagagaa ctttccattg atcagccaat cttattttta acgaatcagc
      301 gctattatga tttgtttgca gataagatca acccgttatt tgcaaatcaa gcaaacaatg
      361 actggtatat ttgtgccaac actcaatgca atcatttaac agaattaaag aacctgcttg
      421 atttcgtcaa acgctatccc gaaaatcaat ccatgtttat catcggattt ggaaatgaag
      481 ggatcatgga tctggcaggt ttttttcaaa aacatacaac ccttgattca tcactatgga
      541 tgatccctgt atcgatccgt tctctaagcc gagcattaac accgcagcgg acgattttgc
      601 agctaccaaa tcgtgtagtg ctgcaaacca tcaatctgcc agaacgcatc gtttatgatc
      661 aaacaatcag cgagcggcag gtggacggaa agcagattga ctttttgact tttatctgtt
      721 gcggaatgat ttgtgatcat cgttttttgc aaaatctgta taaaaactat ccaaataaaa
      781 agcaattaac gactcggccg tttgccggga tgatcgaaga aatgatctat ttttatcaat
      841 tagaggcaga aaacctgtca aattatggta aactgtttga acaagctttt tatctgaccg
      901 aaaatggcca tctactttct gctagtatga aaaaattttt aggaatgatg tttcatttcg
      961 tgtggaatct ccaagcatat ccttttgatt tccaactaaa aaactttttt gtgtggctgg
     1021 acttgcttgg ctatccaatc cactggctgg aacagatttc aaagatggag tatttggaaa
     1081 aagttctttt tttggcagaa aaaagcaaaa aaatacttgt tttagaaaaa ataggtataa
     1141 tagacggata ccaacatcca aacgaaaaag aattattgag aacaatgacg gtatttcaac
     1201 aaatcgtcag tgagataaga gggaattgaa atgaatacaa atagcgaaaa aatgttgcaa
     1261 gctttatcag atgaagactt gtcacaagca caaatctttt tagaaaaagc attaaaagaa
     1321 gacccagcag atatattagc tgaactaggc gaagaattgc tggctattgg ctttttgatc
     1381 gaagcaaaac agatttttga acaactgatc aaccaatacc cagaaaatga cggactgaac
     1441 atcccgttag cagaaattgc aatcgaagat aatgagatcg acttagcttt tgaatacctg
     1501 gaaaaagtgg ataagcaaag tgattactat ccgcaaagct tattggcgat agctgatttg
     1561 taccaagtta tcggaatccc tgaagtgagt gaagcaaaat tgaaagaagc agctgggttg
     1621 cttcctgatg aaccattgat ccagtttgcg ctagctgaat tgtatttttc agttgatcgt
     1681 ttcaaagagg cagcagtggt ttatgaaaca ttgttggcaa gcgggataaa tgaaatttca
     1741 ggaatctcga tgcaggaacg tttaggacaa tccttaagta tgcaaggaga attcgaagca
     1801 gctatcgtac ctttagaaga agcactgaaa gaagaaagga cagatgatcg actgttccag
     1861 ctagctttta cgaatcttca attgaaagaa aatcagcagg caatcaacta tctggaagaa
     1921 cttcgagaag ttaatccgca ttatcaatcg ttatatctat atctaggaca agctcttcaa
     1981 gaagaagaaa tgattgaaga agcacaaaca gtgttagaag aaggaatcaa agaaaatcct
     2041 taccaagtcg aactttatca cctggcctcg gaaaatgctt tccgtctgca tgatagacag
     2101 cgagcagaag aacttttact gaaagcttta gaagtaggag acaaacaaga tgaaacatta
     2161 cttactttaa gtaatcttta cttggatgat gaaagatatg aagatgtgat acaagtgatc
     2221 aatcagatgg aagaaactgc taatccttat gcagaatgga acctagccca tgcttataat
     2281 gaattagaag actttaccgt tgcagctgta cactatgaac aggcttatca tgaactatca
     2341 catgaaccag atttcttgaa agagtatgcc tttttcttaa gagaagaagg gcagctgaaa
     2401 agagcgcaag aattattgac ttattattta acacttgaac caggagatat ggaggcactg
     2461 tcattattag atgacctaac agagaggtga gaaaaatgct aattgatgta cgggaaaaga
     2521 agaatttttt aacgtggatg gtcaatcatg tatcttttag ccgaagagaa gttttttgga
     2581 tcttgaatta tcttgccaat catgaagcga ttttaagcaa tgtccacttt gttgaagggg
     2641 cgaattttgc ggatcgagga ctgcagatca gtgatctatc tgttgaaggg gaacccatga
     2701 aattgttttt gcagggaaaa gaatttacgg acacagacca gatttttcat gaaatccgtt
     2761 tgaattggaa aaagccttta tatgtggaat gtatattcga aaatgcttgg cagacaagag
     2821 aatatctatc tatcttagaa gacaatccat tttcttcttg ggattcttca gtcagtgaag
     2881 aagatactga attaattgaa cgatattttc aagaaaaaga agaagaggca aaactaaaaa
     2941 tgctttatgc tcaaatcgat caagcactag aagatggaga tagggatgct tttttgaaat
     3001 tatctgatga agttaaccga aagatccttt tgcagacaca aaagaaaagt aaccgggtaa
     3061 gtgaacataa caattagtta aaaatagtat agtactaaaa aagacaaagg tcagctggat
     3121 gtggaatctt tcctcatagc ctatctttgt cttttttctt atagtttttt cagtaatctt
     3181 gtctgtggct tcaaataagt aaagccttgc ccttccactt catgcacatt gatgattgaa
     3241 aggaaagctt tttcgtcaat ctcgtggacg atcctcttag cttcagttaa ttcactagag
     3301 ctaacgacca tatagatgat tttttttgaa ttaccagaga atgcgccttc tccagaaagg
     3361 aaagtcacac ctctttgcag accggtcatc agtagtggtg caatctcttc gcttttgttg
     3421 gagacgacaa gtagaccttt tgcagaatat ccgccatcta agatcgaatc aatcacacga
     3481 ctgaaaacat acgaaacaat caacgtatac atcatacgtt tcaagtcgat ataggttaat
     3541 gaagcaagta agacgatgat atcaaatgcc aatagggaac gccccatagt gatgccgtaa
     3601 ttttgttcta aaatccgagc gataatatca ctgccgcctg ttgttccacc catgcggtag
     3661 acgatcccgc ttcctacacc tgcaactaaa cccgcaagta gagaaacgat cagtagatca
     3721 tgctgtaaat tgatttctag tggaaccctt tgccagatcc ataaaaagaa tgacaaagaa
     3781 agtgtaccta gaacagtata ggccaaggaa cgtttaccga ggatctttcc tcctagtaaa
     3841 atcaatggga tgttgattaa taaagtcgta taagctggat caataccaaa taaagctctt
     3901 aagatcaagg tgatccctga gactccccct tctgctaaat gattagcgat gttcaagtaa
     3961 acaagaccaa atgcataaat acttgttcct ataatgataa aaagaacttc ttttactgtt
     4021 tttcgtttga ccatatgaat tccagctttc aattatgtat tttcacagaa tttccattta
     4081 gaaattcctt cctaaatgta gcatggaaat tcgattttct caattgctct tatctaggat
     4141 ttgcgttaaa gttttggtaa gatagttttg gagggaaaaa gatggataaa aagcgttctt
     4201 tatacagtat gcagcaggaa gtggatgaat atatccagca attcaaggtg gggtatttct
     4261 ctccattagc tcagatggct cgattaactg aagaagtagg tgaattggca agagaagtca
     4321 accacactta tggagaaaaa agcaaaaagg cttctgaacc agttaactcg gtagcagaag
     4381 aacttggtga tgttttattc gttacgatga tcatggctaa ttcattgaat atcgacttaa
     4441 ctgaagtttt tgaaaaaaac atggaaaaat tcaatcaaag agaccataat cgctttgagc
     4501 gtaaggacga gtaaacaaga tgaagtggtc ctggccttga agactctgaa acggacttgt
     4561 caaacagtca ccatgcaact gagtctttat ctcaggacaa gaaacacgca ggaaaggttg
     4621 gaaaaatgaa attaaaacaa ttacctctgg aataccaaaa ggcaattcca gttctgaaaa
     4681 aattagagaa tgcaggatat gaagcttatt ttgtaggtgg aagtgttcgt gatatcttgc
     4741 tgaaccagcc aatccatgat gtggatatcg caacaagcgc atttccagaa gaaatcaaac
     4801 agctttttcc aaaaacgata gatattggga tcgaacatgg aactgtgttg gtattagaaa
     4861 atgatgaaca atatgagatc accacatttc ggacggaatc aacttatcag gactaccgta
     4921 gaccagatca tgtcgaattc gttcgttcgt tggcagaaga tttgaaaaga agagatttta
     4981 cgatcaatgc gtttgctttg aaagaagatg gagaaatcat cgatttgttc gatggtctgc
     5041 aagatctaga agaacagatc ttgcgagctg taggcaatcc tcatgagcgg ttccatgaag
     5101 atgccttacg aatgatgcgc gggttgcgtt ttgtcagtca actagggttc aaattagagg
     5161 aagaaacctt ctacgccatc aaagaaaacc acgagctatt aggtaaaata tctgtagaac
     5221 gtataaatgt ggaattcatc aagatgctct tgggaaatga acgggccgcg ggaatccatg
     5281 catttattga aacagagtgc tacatttgct gtcccggttt gaaagaagaa ggcgaagcac
     5341 ttttacgttt tgctgaatta ccatccgtcc cattgaaaga agagagccaa gcatgggcat
     5401 tattgatcag ccaactggat ctaaaagaaa atgagattcg ttcctttttg aaatcgtgga
     5461 agtgttctaa ccaaatgatt aaagacgttc aagcacttgt ccaaggacta cgacaacgag
     5521 aaactggagc tttggaacca ttcgaattgt acttcttagg caaaaaacat gcactgcaag
     5581 tagaagaatt gatgatctat tttgacgaaa cacctcagat ggatgccgta ggagaatcct
     5641 atgatcgttt acctatcaag tcattaagcg aattagcagt agatggtaaa atcttgctag
     5701 aagaaactgg aaaaaaacct ggtaagtggg ttagtgaagc tttgcaatta gctgaaaaag
     5761 ccgtcgtaga acaaagaata aaaaatgata aaaaacaggt tttggatttt ttatcgaaag
     5821 aaaaattgat ttaaaaaaca ctagactgta tctgctcagc tttgttggct acttaaagtg
     5881 ggcagatacg tcattagaag aaaaaacata agatgtgacc acttacataa atttgtgcta
     5941 aactgaggta gtacaagaat aaattacatc ataaaggagt ctttttaatg agtaaagaaa
     6001 tgacagcgct aaaattttat tttagaaatg gagaaacctg gacgatcaac cgccgtcata
     6061 tcggcgatct ttggatcaaa caaatcacaa caagttttgg acgaatcaat ggcagtgaat
     6121 ttgttgaaat ccatccgtgt gctggattta aaatcgaaat cttccatgaa ggggacgcag
     6181 ttgcgacaca tgatatcaac ctaggcggac tggaaatggg catgtttaat cgcgcattga
     6241 aatacgaaga tatcgagcga atggaaatcc tttaccgaaa tggcacacct gatcttgtgt
     6301 acttcccata tctagataaa ggaacagaag gattagacaa tcaatatcaa tcaacaaaaa
     6361 tcagcgaaaa aacaggtaac ttgtatatcg tgatcaatcc agatcaacgt gtagaagatg
     6421 tatacgggga atttttcgaa taaatcgatt tttacgcaaa aatgaggctg tgaaagagat
     6481 gtgtcttatt actactgata ggctgtctct tccacaccgt ttattcagaa taagggactg
     6541 tgacaagatt tttgtcgcag ccccattttt ttgttgtgat aaaagaacaa gaaaggcagg
     6601 aatgggaaag taaacatcct tttgtcagaa acttttatct ttcttaagtt ttacttgata
     6661 tctgatacta tttggaatag aatgaggcgt tgaaaaattt atggaaattt ctaactagca
     6721 ataaacgatg aaacaatgaa atatttttca tccaaaaaga actttgctat aatgatggaa
     6781 gtttgtgtat aggagatctg gaaaatgaga gagagttttg aacaacaaaa aaaactgttg
     6841 catgatcgct atggcgccct ttcgatggat gaccgccgtc aaatactttg taagttgcgt
     6901 aaaagaaata tattgatgta tcgtcagttg gaacgtctga aacatgatct gcttcgtttg
     6961 gagtcaaaac gtgtacagtg tgaattagag gggaaccaaa cacaggttga agtagtcgaa
     7021 accaaaattt taaagaaaaa agaacaattt ttaaaaatgc ttacacaaaa taaaaaataa
     7081 aggggatgga cgatggaatt tgctgagtta gttattgtat ttgcagtaac gatcacctta
     7141 tcgaacatag ctagccgcat tttgccaatg attccagctc cactgatcca aattttcctt
     7201 ggagtggtat taggtctgac agagtgggga caatcaatcg attttgaacc tgaattgttc
     7261 ttagttatga ttattgcacc attgttattt agagaaggag aaaaagcaga tatttcttcg
     7321 attctcaaaa atttcgggac aattttgttc ttggcatttg gaggagtcat tttgaccctt
     7381 gtcggggtag gtgcgacgtt atcattcctg ttgccaagtg tcccacttgc tgcctgcttt
     7441 gcttttggag cagcgttagg tccgacagat gcggtagcag tcagttctct ttctggacga
     7501 gtgaatatcc ctaaaaaggc gatgcatatt ttggaaggag aaggtctttt gaatgatgca
     7561 tctggtgtta ctgccttcca gtttgctctt ggtgcgctga tcaccggatc tttttcagca
     7621 gtaaacgcgg ggatgagtct agtagtttct agtattgggg gagctttgat cggctttttg
     7681 cttgtctggt tcaaacaaaa aataattcat ttgatcgaaa aagcatcagc acaagatgtc
     7741 acagggtatc tgctgatcga acttttgctt ccttttctag cctatgtatt ggcagaggca
     7801 tttgatgtat ctggaatcat tgctgcagtg gcagcaggta ttctccaagc ttctggtttt
     7861 aggaaaatct ctgtgtttga tgcagaattg tcgagcttgt cccacagtac atggacaact
     7921 attgctttta cactgaatgc attagtattt atatttttag gaatcgaatt gacgcaagtg
     7981 ttctcgccag tatggggaga cggtttatat ccaaacggtc ttttattagc gattatcgta
     8041 ttaatctctg tcatgctttt tgtgatcaga ttcatttcta tcagtctttt ttatgtattc
     8101 aaagatggca gtaaaaagtt caaaaaacag ttgaacgaga tcttgatctt aacatttggc
     8161 ggtgtaaagg gaacagtcag tttggctacg atttttattt tgccattttc aatcaataat
     8221 atgatgtttt accagcggtc tttgcttttg tttctgacgg cgggtgtcat cttagtgact
     8281 ttggtcatag ggatcattgt cttgcctatg ctgacggaaa cagaggaagc gaaaagcacg
     8341 gatttgaatg ctttgatgat tttagaagag gtcgttgaag ttttgcgaaa agaaataaag
     8401 gaaattgatc gtaatacaaa agaattttta gccactgaag cagtgataga aaattatcaa
     8461 gaacggatac gtgatctgta cttggaagat ttaaccgatg atgaaaagca agaagtacaa
     8521 gaaatacaag cactgatttt gtcgatcgaa cgggatggat tggatgaaag ttatcgttcg
     8581 ggcaagcttt cttctaatgg ttatcgtttt tactcccgtt ttctttctcg attcgaacat
     8641 tctatcacaa gccagatttt gtcttttatc ggcttttggt tcattgttgt ccgtaggtta
     8701 atgcgaatcg ttctccatcc gaaaatgttt tggcaaagaa gatatgctga tcgtcagaca
     8761 tttattagtg atgaagatat ccaagaaatc agagagacat atcaaaaaaa tactcagttg
     8821 attattgaaa gtttagataa cttgactgat atttatgatg aaacgatggt tcaatttttt
     8881 atccagcaac gcaaacttga aggaataaaa atgaactcgg ggaatttgat ttcttcgtgg
     8941 atgatccagc aagatagtct gtttacgaaa aaaatgctaa gaggttatta tcttgaaaga
     9001 aaaatcattg atgaatacga agttgctgaa aaaatcacga cgttttctgc gaacagctat
     9061 cgcaggaata tcaatttgtt agaatcttat acgatgaaca aaccatctga taacttttct
     9121 ttccgatttg cgtttcgagc aaagtcaaaa aaaacgagtc caataaaata aaaaggtaaa
     9181 aattttcaag ttttataaaa aacaaaacat atcagaacag gatcgaatcg gtcctgttct
     9241 ttttttgaga acacaaaaag aacaaatacc aaaaaaattt tcctgaagtt cactattttt
     9301 atgatacaat atccaagata aggagggaac atgttgaaag aattaaaagt aactgacctc
     9361 aaaaaaactt atggtgaaaa agatttgttt gaccagattt cttttttggt ccacgaaaaa
     9421 gaccgtatcg ggttgattgg gacgaacggg acgggtaaaa caagtctctt aaatattatt
     9481 gccggtatcg atagcagcga cggtgatcgg caaacagtgt tttatccaac tgattaccgt
     9541 attggttatc tttctcaagc agctgaattt tccgatgaat taactgttct ccaagcagtc
     9601 tttcaaggaa acagcccctt gatccaaact gttcgagcat atgaggaagc attgatcgaa
     9661 ctaggggaaa acggagaaga ccctgatgtg caaaaacgtt atgctaaagc agaagaacaa
     9721 atgaataaag aagatgcttg gactacagat accaacgcaa agattatttt gcaaaaatta
     9781 ggaatcagtg aattagataa aaaaatcagt actttatcag gtggtcagaa aaaacgagtt
     9841 agtctggcgc aagtgttgat tgatgaaccc gatttactat tactagacga accaacaaac
     9901 catttagatt atgaagcgat cgagtggttg gaaaactatt tgaaacaata ccgtggcgca
     9961 ctattgatgg ttacccacga tcgttatttt ctagatagag tagcaaaccg aatcttcgaa
    10021 ctttcatttg gaaaattata cgagtataaa ggaaattatg aagcttacgt cttagaaaaa
    10081 gcagaacgtg atcgtgtaga agtagaacaa gaagaaaagc gcaagcggct ttataaacag
    10141 gaattagctt ggatgagggc tggcgtacag gcacgtggca ccaagcagca agcacggatc
    10201 aaccgtttcg aagatctaaa ggagaacttg taccaagtaa accaagaaga tgatttagag
    10261 ctgaacctag cgacacaacg tttagggaaa aaagtactgg aaatcaaaga tggcagttac
    10321 cgtataaatg accaaacact gctagaacat ttagatttat tgattcaatc tcgggaaaga
    10381 ctaggtatta ctggtaaaaa tggtgcggga aaatcgacat tgcttaatat tctagctggc
    10441 agaattcccc tggatagcgg tacaatgtct atcggtgaaa cggttcatct tgcgtattat
    10501 acacaagaaa atgaagaaat ggcaccagat aaacggatga ttgcttactt acaagaagct
    10561 gctgaagaag caaaaacagc agatggcagt caaatcggag tagcagaatt acttgaacga
    10621 tttttatttc caagatttat gcatgggaca ctgataggca aactttcagg cggagaaaaa
    10681 cgccggttat ttttgttgaa actgctgatt cagcaaccta atgttttatt attggatgaa
    10741 ccgaccaatg atttggacat agcaacattg acgattttgg aagattattt tagaagtttt
    10801 ccaggtgctg tgatcactgt ttcccatgac cgttatttct tggacaaggt agcagataag
    10861 ttattagtat tccaaggaaa cggaaaacaa gaactttatt acggaaacat gtccagttat
    10921 ttactgaagc aaaaagagac ccagcagcct gctgaaaaag cgaaaccaaa aatacagagc
    10981 aaggaacctg ctgaaaagaa gaaattatct tacatggaac aaaaagaatg ggaaacgatt
    11041 gaagatgaga ttgcagaact tgaagaaaaa atctcattgc tccaagaaga gatgaatcat
    11101 caaggagata atttcactcg attacaagaa ttgcaaaacg acgtatctga aacagaagca
    11161 caacttgaag aaaaaatggc acggtgggaa tacttgagtg aatgggtaga agattaggag
    11221 gaaaaaggat ggaacaagcg tatcttgact taggaagaaa attgttggaa gaagggcatc
    11281 gtaaagaaga cagaacaggc acaggcacat taagcttatt cggataccaa atgcggtttg
    11341 atctgcaaaa agggtttcct ttgttaacaa cgaaacgagt accttttgga ttgatcaaaa
    11401 gcgaattgct ttggttttta aaaggagata cgaatatccg ctatctatta caaaataaaa
    11461 accatatttg ggatgaatgg gcatttgaac gctacatcaa aagtccagac tataatggac
    11521 cagatatgac tgattttggc catagatgtt tgacagatcc tgaattcaat gaagaatata
    11581 aaaagcagag caagcttttt tgcgagaaga tcctaaccga tgattccttt gctgaaacat
    11641 acggcgatct tggacacatc tacggctatc aatggcgtca ctgggaaaca aaagacggtg
    11701 gctttatcga tcaaatcaaa caagtgatcg aagcaatcaa aaagactcct gattctagaa
    11761 gattgatcgt ttctgcatgg aatccggaag atgttcctag catggctttg cctccttgtc
    11821 atacgatgtt tcaattttat gttcaagagg gacggctaag ctgccaattg tatcaacgca
    11881 gtggggatgt gtttctaggc gttccgttca acattgcaag ttatgcgttg ctgactcacc
    11941 taattgcaca tgaaacaggt ttagcggttg gcgaatttgt tcacacatta ggagatgctc
    12001 atctttatat caatcatatc gaacaaatga aagaacaatt gagccgagaa atacgcgcat
    12061 ttccgacttt agttttgaat caggaaaagc agtcagtatt tgattttgag atggaagata
    12121 tccaattaga aggatatgac ccacatccgg cgatcaaagc tcctatcgct gtttagaatc
    12181 agaaaggatg agaaaatgtt agctgcaatt tgggcacagg atgaaaacgg attgattgga
    12241 aaagaagacc gtcttccttg gcgtttgcca aatgatctga aattcttcaa acaaatgaca
    12301 gaagcaaata cactagtgat gggacgaaaa acattcgaag ggatgggtag ccgtccgttg
    12361 ccgaatcgtc agacgattgt tttgacgaga gattcttcct ataaagcaga aggcgtgcat
    12421 gtcatgcata gtgtggaaga cgtgcttgct ctggaaaaag aaacagacgg tatctttttc
    12481 atcgctggag ggtcagctgt ttatcaagaa tttctgccat tttgtacgat attataccgt
    12541 acagtcatcc atcatgtatt cgatggagat gcttattttc cacctgttga ctggtctgat
    12601 tggtcactga tcaatactag tcaaggagaa atggatgaaa aaaatcgtta tccgcatcaa
    12661 tttgaaacgt atcagcgtaa tgagaatcct gtaaaaagcg ggacaggcga attgacgata
    12721 taaaaaagct atggatagac tagctgttat ttagagctgt cccatccata gctttatttt
    12781 ttttattaag taaagaataa aacagagaag tacataaaac ctgcacctaa cataacaaac
    12841 aaatgccaaa caacatgcat atagcggata gaattcaagc tataaaagaa tgcgcctatc
    12901 gtgtaagaaa gcccgcctgc taccatcaaa ataacaccag tcattccaag agagtgataa
    12961 agaggaacag cagccacgac acagagccac cccataaaaa tatagatgat cgtagatact
    13021 tttgatactc tctcccgttt atgcaacgtc aacgctttat atataatgcc aagaatcgca
    13081 aacaaccaga ttaatacaaa taaagtccaa cctagccatc ctcggatact cagcaaacaa
    13141 aaaggagtat aacttcctgc aatcaaaaga aaaatcgaac tatgatcgaa tacttggaac
    13201 accttttttg cttttgtaaa aatcaatgaa tgaaacaaag tagacgttaa aaataaaaga
    13261 atcatcatcg atccatagat agcataagag acaatatgga gggaggaatg caagtgggca
    13321 ccttttacta aaagaaccac tagtcccgcg atactcaatc cagtcccaat tccatgggtg
    13381 actgcattaa acacttcatt taatatttca tacgttcgat taaatttcgt tttttccatg
    13441 aaaacggctc ctttactagg tgtaattaat gaaaaatcat tatttgtctg ttatactaaa
    13501 aatagaaatt gtcttacatg tagtttaaca tgaataaggc atcttgttaa agaaagagag
    13561 agagaaaata atgacaaatg taaaaatcgt aacagattct tcatgtacga tggaaaaaaa
    13621 tgtacgcgat gctttaggca ttcgtgtcat gccgctatcc atcatgatcg acggaacagt
    13681 atatcccgat gatgaccaac tagacggcga aagatttatg gaaatgatgg cgaaagcaaa
    13741 aaatctgccc aaaacaagcc aaccaccaat tggagaattc atctcgatgt atgatgagct
    13801 aggagaagac ggcagtgaag tgatttcgat ccatatgaca aaaggcttga gtggaacagt
    13861 agaagcagca agacaagcca gtaatctaac aaaaacgaaa gtaacggtta tcgacagtga
    13921 taccactgac caaggattat cttttcaggt aattcgagca gctgaattag caaaagaagg
    13981 taaaacagta gagaaaatcc ttgaagaagt caaaaaagta caagacaata caaaattata
    14041 catcggaata tccacactag ataacttggt aaaaggtgga agaatcagcc gaacaactgg
    14101 tttgctgtct agtgttttga acatacgcgt ggtgatgaat ttcgcccatt ctgaattaat
    14161 ccctgtaact aaggggcgag gaaagaaaac gttcgataaa tggtttaata atttgaaaaa
    14221 tgaactgaaa gaattgccaa atgtgcgaca aatcggtatt tcacatgcgg atgcaaaaga
    14281 attggcgcaa gaattcaaag agggtttgca agaattattc ccggacatgc atatccctgt
    14341 actgcatacg aatccggtta tcgctacgca tactggtaaa gacgcgtttg caatcatgta
    14401 ttatgtagat tagtcgaaaa gaggataagc cctcagcctg aaaggcttgc agcttattct
    14461 ctttttcttt ataaaattag gaaaataatt gttttctttt ttcataaaga ctaccttttt
    14521 gataaaattt ttgataacat tagaaccaat cgaatacaag aggtgaaaaa atgaaattaa
    14581 cgaaacgaca tttgatcctc gttttgttcc cattattaat tgcgatcatc atctatgcag
    14641 gtttagctgc ttctataccg aaagctggcc cactaatgaa accagtaact actgtgagag
    14701 aagatccaaa taaaaaagaa aaacttcact acatagctat cggagattcg ctgactgaag
    14761 gagtaggaga tcaaaccaag caaggaggat tcgttcccct tgtcgcaaat gatctaaaag
    14821 accgttataa tttgaccgcg gttgaaacag aaaactatgg tgtaaatggt gaacgaagtg
    14881 accagatctt aaagcgagta aaaacaaaag aagaaattcg aaacaatatc aaaacagctg
    14941 attttatcac actgactgtt ggcggtaatg atttgatgaa agttatccaa aataatttat
    15001 tcgggttaac ggtcaattcc tttaaaaagc cactgaaaaa ctatcaggaa aatgtcacag
    15061 aactattgga agaatttcga tccctcaata aaaccgcacc tatttacatt ttaggcatct
    15121 acaatccatt ttatttgaac tttcctgaga tcactgacat gcagacaatt gttaacaatt
    15181 ggaacaaagg aacagaaacg gtgacaaaaa aaatgccgaa ctgctacttt atcccaatca
    15241 atgatttgct ttatcaagga ttgaatcagg aagtaggtgt cacagaagaa ggaacagatc
    15301 aaacaactag cacgacagaa aatctaaatg gcatcaaaaa taatgtgctc tatgaagaag
    15361 atcatttcca tccaaataat ttaggttatc aattgatggc aaatgcagtg agagatcagc
    15421 tgatcgagac acaaaaccaa tggttagaga aggaggatga tcaataaaca tgaaaacaag
    15481 atctgacgta tcttcaaaca aaacaaagaa aacaaattac tggaaattcg ccttccttat
    15541 ccttcttggg gtagtacttg gttcgaccgt atttttaggc agccgtattt ttgctaatcg
    15601 ggaaccagaa ctcccagaaa taccagctct tacggaaaga caaggagatc ctgtcttaac
    15661 gatcaattca aataaagaaa aagtcaatca aatcatcagc tttttcctta gtgagtatca
    15721 aaaagatagt gatattgaat ataaatttta tttggaaaat gaagcactac tcaatggtac
    15781 tttcgaagta ctaggttttc ctatcgattt ctatttatat tttgatccgt atgtgatgga
    15841 aaacggaaat gtccaactaa aagctagaag tctttctatc ggaacattga gtttgccaat
    15901 caaagatgtg atgaatatga tcaagagaaa ctataaatta ccagattgga tcgaagtcaa
    15961 tacagatgat ctgactatca tgcttaggtt ggatcaattc cgaatgcaaa acgggatgta
    16021 tattaaagca gataaaatcg acttagtaaa tgatgacatt cggtttagtc tatatttgcc
    16081 aaaagatacc tctgatgctt caaacaactc aaataccaac aaaactagca ccagcagtac
    16141 tgaaagcaag acaaaagaaa ataaaaaatc atcggatgag tagtattaga gggggaatca
    16201 taatggaacg agcaatattt gcaggaggct gcttctggtg tatgatccag cctttcgaca
    16261 cgcttcctgg tatccataca gtgatgtcag gatatactgg agggcatgta ccagatccga
    16321 cttatgaaca agtaaaaagc caaacgactg gacatacaga agcagtggag attatctatg
    16381 atccaacatt gatttcatat gaacaattag tagaacttta ctggcagcaa actgatccaa
    16441 ctgacgcttt cggacaattc gaggatcgcg gtgacaatta tcgcccggtg atcttttatt
    16501 tgacagaaga acagcggatc attgctgaaa aaagtaagaa acagttagct gaaagtggac
    16561 gtttcgaaca gccaatcgtt acaaaaatcg aaccagccca accattttat ctagcagaag
    16621 aagaccatca agagtattat aaaaagcatc ctgaaaattt taaaagaaac catgcacgcc
    16681 gggctgcctt tatcgaagaa aattggagga acgaagggtg aatcgaagct tttttcatta
    16741 tttaatgaca ctgcgaggcg gtggcacaca tgatgcttta tctgttttcg ctacagaagc
    16801 cggtaaagac atccaatttc ctaagcacag ctctagctac gaagaaattt ctaattatct
    16861 ggaactgaat gtcgactatt tgccgtccat ggatatcttt gacgaagcat gggaaaaata
    16921 tttagaaaat aatcatgaca tataagagat agttttgtac tttatgatca aaaaagtttt
    16981 ttgtccaata gcctaattga aagaattatt tttatttcag ctatctagtc gcattttttt
    17041 gatatttttc ttataataaa gaaagaatga aaaaaagagg gatggattga tagagattga
    17101 caaaaaaaca acgctatatt aatcgcttct ggcttgtatt caaatactta cttgtttctg
    17161 tattccttgc gttcatgttg cggggatttt tattcatccc ggtaccagtg gaaggcaatt
    17221 caatggaaaa cgtgttgaag caaggtgata tggttgtgat ggaaaaattt tcggagatca
    17281 gacgatttga tattgttgtt tttcaattag cagatggcac gatttatatc aaacgagtaa
    17341 tcggtcttcc aggagaaaat gtcagctacc aaaatgatca attgaagatc aatgggaaag
    17401 tagttaagga accttatcta actaaaaacc tgaaatcaga tcatgcaaat gcatcctata
    17461 cgacggactt tacactacaa gagctaacgg gacaatccaa gcttccggaa gataattatt
    17521 ttgtacttgg agataatcga agagtttcaa aagatagtcg ttcgtttggc acgatcaata
    17581 aaactgatat tctaggtaaa gcaagatttg tctattatcc acttgatgaa ataaaatgga
    17641 tccagtgaga aacaataaag cgtgcagtct gttgagactg cacgctttat tgtttaatcc
    17701 aaaatcagtt tactacctta gtacgtaaaa tcaaacagct cgtttaaaca cttttctagc
    17761 ctctaaagtt ttgataaatg aataaacaac cattatttga atagggattt ggatcatatt
    17821 cctgatgaat ctacctagaa aaattacttt gaaatctgca ccaaacaaaa cagacatcag
    17881 ccaagaattg ataaaaaggc tgactgggat cataatcaat aattgggcag cgatgacgga
    17941 aggcaggttt atctttttat gatataaaaa taagccatta ataaatccac caaggaaagc
    18001 cgtgataaga aaagcagctt gaaacgttcc tgaaccaaat atcgtgaaat ttaaagtgtt
    18061 cgacaacatt tcaagcaaac cagcccagat cggtccatat agataaccca taagcgccat
    18121 acttaaaaat ccgaatgtga tttgaaaata agcaggacca atcgctatct tgtataagat
    18181 gacatcaagg gctaataaaa gagcagaggt cgacaacaat cttgcattca tttcgggcaa
    18241 tctaaaaacg tcttttgcaa tcaaagtgtt caaaatattc tctcctttgt cagttaataa
    18301 taaaaggata ccataaaatc accaatgtgt catgacacat tggtgattta catacactgg
    18361 catctaacaa ttaaaaaaag ggtgagaaga ctgcttttat aaactgtaaa aaagagattg
    18421 tacgaataaa aaaaatagag gcggagaata cttatcgtat catccgcctt tgtttttttg
    18481 ttataaaaaa cgtcagatta gttatctgct tacatcttca tccatacggg ttctaatgta
    18541 tttccgtcta gatcttggac ttctaatgaa aacatttctt cttcaggcat tcccatatct
    18601 acttcgtgga aagtaccacc attttctttt gcaatttgag caaatttttt tacttcatcc
    18661 gcattttcaa cactaaacga aatcaaagca ccacttgttt ttttattatc agctatttct
    18721 ttatctttta taaatttttt ataaaaatca tgagagagaa gcattatcca aaaagtgtca
    18781 tcccatacca ttgaaccagc ttcttcagta gaaaattctt catttttttt aaaacccagc
    18841 ttttcataaa aagcaacgga acgattgaca tcagcaacag gaaaattaac aaaaaccata
    18901 ctattcattt gtttcgtctc ctttctgttt tgttcgtcta tcatctctta tttaggaaac
    18961 gctgtcaaaa atttagattc atatatagaa accaaaataa aaatttgcat catcaaaaaa
    19021 gtgaagatgt gatagaatga ggactggttc actttcactt aactaataga tggaatttct
    19081 ttataataaa aaagtgaatt tatattgaaa aagaaaaaaa caagtaaagc cggggaatat
    19141 tccggtatga aaggaatgga gagaacaatg accatccaat ggtttccggg acatatggca
    19201 aaagcccgac gagaagtttc tgaaaaaatg aaatatgtgg acatcgtatt tgaattggta
    19261 gacgcacgat tacctttatc ttctcgtaat ccaatgctag atcagatcat tcagcaaaaa
    19321 cctcgccttg ttttattgaa taaagcggat ctggcagatc cacaacagac aaagctgtgg
    19381 caagaatatt ttcgtaaaca aggccatctt gcattagcta tcacggcaca agaaagtaaa
    19441 ggaattaaag gtctagtacc tgcggctaaa gaagcattga aagaaaaacg ggcaagagat
    19501 gctgctcggg ggatcaagcc tcgcgctatt cgggcaatgg tcttaggtat tccaaatgtt
    19561 gggaaatcta cgttgatgaa tcgactagta ggcaagaaaa ttgcacagac aggaaataag
    19621 cctggcgtaa caaaaggtca gcagtggctt cgtttaggta atgagttgga attgttagac
    19681 acaccaggga ttttatggcc caaatttgaa gatgaagaaa tcggcaaaaa actagcgctg
    19741 acaggcgcga tcaaagacca gcttgtccat ttagatgatt tagcgattta cggattagac
    19801 ttttttgccc gatattattc aggaagaatc agcgatcgtt atggtttatc aatcgagcaa
    19861 gaagaaaaat tggcaccgga attactgatg gatattacag caaaacgtgg gtataaagaa
    19921 gactatgatc gtggcagcga attagtcgtg catgatattc gtcaaggaaa acttggacga
    19981 tacacactgg atcgttgcga agaaatggag caaaaaagtg atgactgaat ccatccaaag
    20041 tatcaaagaa cgattgaaaa gcatacagag aatagatgat cctacactag aatcattaag
    20101 aaatgatcca cgcaaaggcg tgcagcaagc actggcttct tttgaacgac gattgaaaaa
    20161 ggaagcatta attaaggaaa aatatgaaga aatgttttgc tttgaaaagc aagggtacgc
    20221 acaaggtcac caatggattg ccggcattga tgaagtagga agaggaccat tagctggacc
    20281 tgtcgtggca gctgcagtta tcttgccgaa aaatgagatc atattagggc tgaatgactc
    20341 caaacaatta tcagagaaaa agcgagaact tctttatcaa caagttcaag aaaaagccct
    20401 ggcaatcggg atcgggatcg ttgatcagca gacaatcgat gatgtgaata tttatgaagc
    20461 aagtaaatta gcgatgatcc aagcagtaga aaaattgtcc attgtaccaa gctatttgtt
    20521 gatcgatgcg atgaccttgg atttgcctat tcagcaggaa aaaataatca aaggggatgc
    20581 acgatctgtg tcgattgctg ctgcaagtat cattgctaaa gtatatcgag accaattgat
    20641 gaaagaatat gacgtgcttt atcctggata tggtttctcg cataatgcag gttatggaac
    20701 aaaggaacac ttagaaggac ttgaacgaca aggaattacg ccaatccatc gtaaaagttt
    20761 tgcacctgta aaaaaatatt tacaataaaa aacagccgct tttacgtatc ttattagaaa
    20821 gagagacgaa aggcggtttt atgatgtatc aaatagaaga aaatttattg aaacttgctt
    20881 atacaaaagg aatcagtagt caaggaaaat gggcacttgc taactggatg atgcagtatc
    20941 cttataaaga aatcggattt gaagacatca ttaagatagg taaaataacc aaacaccggg
    21001 agctgtttcg caaaagttgg caggaaattc acgctaactg gggcaaaatc caatcgaaac
    21061 agtcgtttat cacttgcttt gatcccaaat atccccctca gctgcttcac ttgacctatc
    21121 cgccaattgt actgttttat aatggtgatc tatctttact ttcttgtaac atgttaagcg
    21181 ttgttggtgg aagacacact tctgctttag ccaaaaaaac agtttattat ttactaaaac
    21241 cagtgataga agctggatat gtgatcgtca gtggctgcgc gaaagggata gatacatacg
    21301 gtcaccaagc agcaatctct catggtggac ggacaatcgc agtcattgga acagggatag
    21361 agcaagtcta tcctgctgaa aatcgtgact tgcaagaggt gattgcaaat gatcatcttc
    21421 ttttgagtga atatcctcct caatccggcc cgaaaaagca ttgttttcca atgagaaatc
    21481 ggattatcgc agctttgtct aaaggaacat gtgtctttga agccaagaaa aaaagcggct
    21541 ctctgataac agcacagcaa gcattggatc ttggaagaac agttttttct gttccaggaa
    21601 atattttaac agaacattct accggatgtc atcatttgat ccaagacggt gcagtttgca
    21661 cggtttcggg tgaagatatc ttggcagaat ttaaagaata acaccatact tttcatttgc
    21721 ttttcttgac aaacgttttc tgaatggata tgattagcta cgatttgtat gaatcctctt
    21781 ttaatagtag gaacacgaca atggaaagga gtccattcag taatggcgta taaatattta
    21841 gtgattgtag aatcacctgc aaaagccaag acaattgaga aatatcttgg acgaaactat
    21901 aaagtaatgg ccagtgttgg ccatataaga gatttaccga aaagtaaaat gggtatcgat
    21961 tttgaaaaca attatgaacc ccattatatt tctatacgcg gaaaaggcga tgtcatcaaa
    22021 agcctgaaag ccgcagcaaa aaaagctcaa aaagtttact tggcaagtga cccggataga
    22081 gaaggagaag cgattgcttg gcatttagcg tacctacttg ggttggatct gaaagaaaaa
    22141 aatcgggtgg tcttcaatga aatcacaaaa gacgcagtca aagcagcttt taaggaacca
    22201 agaacgatcg atgtagattt agtagatgca cagcaagctc gtcgtacctt agacagaatc
    22261 gttggttatt cgatcagtcc tattctctgg cgtaaggtca agaaagggtt aagtgcagga
    22321 cgtgtccaat ctgtcgcttt aaaaattatt attgaccgtg aaaaagagat ccgagaattt
    22381 gttccagaag aatattggag catcgacggt aattttaaaa aagctcgcaa gaaattcaaa
    22441 gcaaatttct ggggaatcga cggtaagaaa aagaaattac cagatgcaca aagtgtaaaa
    22501 gaagtcactg ctagaattga tggaacagac ttcgaagtta aaaaagtaga aaagaaagag
    22561 cgcaaaagaa accctgcgaa tcctttcact acaagtagcc tgcaacaaga agctgcccgt
    22621 aagttaaact ttcgaacaag aaaaaccatg atggtagcac agcaattata tgaaggaatc
    22681 actttgggta aacaaggaac agtcggcttg attacataca tgcgtactga ttctacccgg
    22741 attgccgata cagcaaaagc agaggccgca gcatttattg aagatacgta tggaaaagaa
    22801 ttttctagac atgatcaccg aaagatcaaa aatgctcaag gcgcacaaga tgcccatgaa
    22861 gctgtgcgtc caacgagtgt gcttcgtaca ccagatgaac tcaaacaata tttagataaa
    22921 gatcaattga aactttatac attgatctgg tcacgttttg tggctagtca gatgacacca
    22981 gctattttag atacaatgaa agtgacatta gaacaaaatg gtgtcatctt cattgcgaac
    23041 ggttcaaaaa tcaaattcaa aggattcatg caagtgtatg tggaaggtag agatgacggc
    23101 aaagaagaga aagaaaatat tcttccagaa cttgaagaag gcgatgtagt ccaatctgtt
    23161 gatattgaac caaaacaaca ttttactcaa ccaccagcac gttttagtga ggctacgttg
    23221 attcgtgcac tagaagaaaa cggggtaggg cgaccttcca cttatgcacc aacacttgat
    23281 acgatccaaa gacgctacta tgtaaaattg acacaaaaaa gatttgagcc gactgaacta
    23341 ggagaaattg tcaattcatt aatctgtgaa ttcttccctc aaatcgtcga tatccatttc
    23401 acagcagaaa tggaaggaga tttggataaa attgaagaag gcacggaagc gtgggtcaaa
    23461 gtggttgatc gtttctataa accgtttgaa aaagaactga cgaatgcgga agaaaaaatc
    23521 gaaaaaattc aaatcaaaga tgaaccagca ggattcgatt gtgatgtctg tggacatccg
    23581 atggtgataa aattagggaa atatgggaag ttttatgctt gcagtaattt tcctgattgt
    23641 cggaatacga aaccaatcgt aaaagaaatc ggtgtgactt gcccagtatg tcatgaagga
    23701 caagtcattg aacgaaaatc taagaaaaac agactattct atggttgttc ccgtttccca
    23761 gaatgtgaat tcacttcttg ggataaacca gtgggcagaa attgtccaaa atgtgacgga
    23821 tatctggtcg agaagaaagt caaaggcggt aaacaagtag tctgtgtaaa tggagattac
    23881 gaagaagaca tccaaaaata atagaaaaga ggttctttca ttgaaaatgg taaatgttgt
    23941 tggagcaggg cttgccggaa gtgaagctgc ttggcagatc gcacaagcag gagtccctgt
    24001 ccgtttatat gaaatgcgtc cagtcaaatc gactgaggcg catcacacaa gtaattttgc
    24061 tgaactagta tgttccaatt cattaagagg aaacagtttg gctaatgcag tagggttatt
    24121 gaaagaagaa atgcgccgat tgaattcggt agtaatcact tcggcagatg aaacagcagt
    24181 gccagctggt ggtgccttag ctgttgaccg cgattctttt tctgaaacaa ttacccgaaa
    24241 agtcaaagag catccattag taacagtgat aaacgaagaa attactgaaa taccggaagg
    24301 aatcaccgta gtagcaacag gacctttgac ttctcatcca ttagcagaaa gcatcaaagc
    24361 attcaatggt tcagatggtt tttatttcta tgatgcagct gcaccaatcg tagacaaagc
    24421 tacgatcgat atggataaag tatatttgaa gtcccgctat gacaaaggag aagcagctta
    24481 cttgaactgt ccgatgacag aagaggaatt caaagctttc catgaggcac taatcaatgc
    24541 cgaagtggca gaacttaaat cttttgagaa agaaaaatat tttgaaggat gtatgccaat
    24601 tgaagtaatg gcacagcgag gattcaaaac gatgcttttc ggacctatga aaccagttgg
    24661 attggaagat cctaaaactg gcaaacgtcc ttatgctgtt atccagctgc gtcaagacaa
    24721 tgctgcagct tctttataca acatcgtggg ctttcagact cacttgaaat ggggcgagca
    24781 aaaacgtgtt ttccggatga ttcctgggtt agaaaatgct gaattcgttc gctatggtgt
    24841 gatgcaccga aacagcttta tgaattcgcc agaattgctg aaaccgactt accaatcaac
    24901 gaaacgcgaa gatctgttct ttgcaggtca gatgactggt gtagaaggct atgttgaaag
    24961 tgcagcgagc ggactacttg ctggaatcaa cgccgcacgc ttagcaaaag aaatggaacc
    25021 agtcgagttt ccacaagaaa cagctattgg aagtatggct tactacatta ctcatgcgga
    25081 aggaaaacat ttccaaccga tgaatgccaa ctatggtctg tttcctgaac tgccagagcg
    25141 cattcgagac aaaaaagcaa gatatgaagc aattgcacaa cgagctttaa aagctaatga
    25201 ggcaataaaa acagaattag aaaaaactgc aatcccaaat gagtaaggaa actccatgaa
    25261 gagggtgaga cggatagtct cgctcttttt cttgcgtttt tcttaagaat ttctcaaaca
    25321 aaatgtgagg aattgcgcca attgtgaaca aacttagaaa tattggttaa attctgacaa
    25381 tttatttgtc tttttataaa cgctgtgcta aattattctc tgggacaaaa ggaaggtgag
    25441 aaaatgacag aagccacgtg ggaacaaaaa tttttgcgtt atttgattgt cgaaagagga
    25501 tattcagaaa aaacgaaaga agcatatgaa gaagacattc tccatttcaa acattttttg
    25561 gaggaatctg gagacgctga tctgctgaag gcggaatatt ttacggttcg tgtctatttg
    25621 agtgcattag ctgatcatcg tcctagctat agcagaaatt ctatcagtcg caagatagcc
    25681 agcctacgtt cgttttatca gtatcttctc aaagaagaag tgataaaaga aaatccattt
    25741 tcttacgttc atctcaaaaa gaaaaatttg agactgccac gtttttttta tgaaaatgaa
    25801 atgcaagcac tttttgacag cgtagcagga gatagtcctt tggatttgag gaaccgcgct
    25861 ttactggaag tcctttacgg gtcaggcatc cgtttaagtg agtgtagcag tttgtcggta
    25921 tcagacattg attttgattc agaggtcatg ttgatccatg gtaaagggaa caaagagaga
    25981 tatgctcctc taggttcttt tgctcaagat gctctgcaag aatatttcag ggaaggccgc
    26041 caggtattga tgacaaaata tcacgaagag catgatatcg tttttgtgaa tcatcatgga
    26101 aaaccaatca cgcctactgg aattgaatat gtcttgaatc aaatgatcaa aaaaagcagt
    26161 ttggatagtg atatccatcc tcacatgctg cgccatacat ttgctactca tttattaaat
    26221 aatggggcag atttgcggac agtccaagaa ttgctaggac atgccaattt atcgactacc
    26281 cagatctatg cccatgtaac aaaagaaagt ttacaaaaaa actatcgttc tttccatcca
    26341 agagcgtaaa aataaggaaa agaacaaatt taggaggaaa caaacatggt cgaatcacca
    26401 tttcattcaa ccactatctg tgccgtcgaa aaagacggga aatttgctat ggctggagat
    26461 ggccaagtaa caatgggtga atctgttgtc atgaaaggca ctgcaaagaa agtacgacgt
    26521 atctacaatg gagaagttgt tgtaggtttc gccggaagtg ttgcagatgc gtttacttta
    26581 gaagaaaaat ttgaaggcaa actaaacgaa tataacggga atctacaacg cgcagctgtc
    26641 gaattagctc aagaatggcg gacacagcaa tctatgcaaa aacttgaagc gatgctgatc
    26701 gtaatgaatg ataaagaaat gcttcttgtt tcaggtacag gagaagttat cacaccagat
    26761 gatggtatct tagctatcgg atcaggaggg aattttgcgt tggctgcagc ccgagcaatg
    26821 aaaaactatg ctcaaaacga catgagtgcg aaagaaattg cagaaaatgc gttaaatatt
    26881 gccgcagata tctgtatctt tactaatcat aatattatcg tagaagaact gtaagaggtg
    26941 agtagatatg tatgaattaa aacaaacacc aagacaaatc gtaagtgaat tagatgaata
    27001 tatcgtagga cagcacgcag caaaaaaatc tgttgccgtt gctttgcgta accgctatcg
    27061 ccgtttgcag ttagatgaaa aaatgcaaca agatattaca ccaaaaaata tgctgatgat
    27121 cggacctaca ggggtcggta aaacagaaat cgcacgacgt ttggcaaaaa tcgtcaatgc
    27181 accatttgtc aaagtcgaag caacaaaatt tactgaagtc ggttatgtcg gaagagatgt
    27241 agaatcaatg gttcgggatt tagtagaaaa tgcgatccaa atcgtagaaa aagagcagta
    27301 cagccgtgta tacacaagtg ctaaaaaaaa tgcagaaaaa cgtttggtaa aaatcttggt
    27361 acctggtatc aaaaaagaac agaaacaatc cactaatcaa tttgaacaaa tgatgaatct
    27421 ttttaatgct agtcagcaaa ataccgctga accgcaagaa gaagtgacag aagatattcg
    27481 aatcaatcgc cgtacagtct tggaacaact acaaaagggt ttactggata gtcgtgaagt
    27541 aaccattgaa gttgaagacc aaaagaaacc tgcaccaatg atgaacaatg gattggagca
    27601 aatggggatc gacctaaatg aaactctagg tgctttgaca ccgaagaaaa aagtggaacg
    27661 gacggtaaca gtcaaagaag ctttagagtt attgatcaag gaagaatcag caaaattagt
    27721 caaggatgct gatatccata gtgaggcaat caaattagcg gaagaaagtg gaattatttt
    27781 tatcgatgaa atcgataaga tcacttctaa atcacagcaa tctggagaag tatccagaga
    27841 aggcgtccaa agagacatat tgccaattgt cgaaggttca caagtaaaca caaaatacgg
    27901 gatcatccaa acagatcacg tcctattcat tgcttcagga gctttccatt tgtctaaacc
    27961 aagtgatcta attccagaac ttcaaggacg cttcccgata cgggtagaat tagatgattt
    28021 gacagctgaa gattttgtga agattctgac cgaaccaaat aatgctttag taaaacaata
    28081 cgtcgcgttg atcggtacag aaaatgtgtc agttacgttt acaaaagaag caattgaacg
    28141 gatcgctcaa atcgctttcg atgtcaaccg tgacacagat aatatcggcg cacgcagact
    28201 gcataccatt ttggaaaaac tactagaaga tctattattt gaagcaccag atatgcaaat
    28261 gggagaaata acgatcacag aagcatatgt ggatgacaaa cttggctcaa ttgcggcaaa
    28321 tgaagattta agtcgctata ttttataaaa aatcggagga cgacaatgac agacttgcta
    28381 acgaaaaccc gcaagataaa cacacttttg cagcaaaaga atacttttga catgcaagca
    28441 gatttgcctt acgataaaat ggctgtcaca ctaggtggta ttcttgacag caacacctat
    28501 atcataggaa gtgacggagt attactaggt tataatgaac gtcacgatgt gaacaatgaa
    28561 cgaatcaaaa caatgtttgt tgagaaacaa tttcctgaat cttatactga tacagtggca
    28621 cagttgatga aaactgaagc taatatccca attactagtg atattactgc atttccggta
    28681 gagtcaagag agaaatatcc atttggtctg acgactgtcg ttccgatctt tggagctggc
    28741 gaacgtttgg gtacgattat cttatctcgt atggaacaat cgtttgcaga tgacgatcta
    28801 gtcttagcag aatatggagc tacggttgtc ggtatgcaga tcctttatca gaagtctcga
    28861 agcatcgaag cagatgtacg gagtgcaacg gctgtccaaa tggcaatcaa cacattatct
    28921 tatagcgaat tgaaggctgt acaagctatc tttgaagcat tggatggaga tgaaggtcgt
    28981 ctgactgctt ctaatattgc cgatagtatc ggcatcactc gttctgtgat cgtcaatgct
    29041 ttacgaaaat tggaatcagc tggaatcatt gaatctcgtt cgttaggcat gaagggaact
    29101 tatttaaaag tattgaattc ccgttttaaa gacgagttag caaaacacag ttattagaag
    29161 taaggggact ggggcagata gaaatgtttg ttccagcctt cccattttaa aaagtaagtc
    29221 gaagttggag gaatggcaat gactgttatt attcaaaatg accagctgat cgccgaaatc
    29281 gctgaacacg gtgcggaatt gatcagtctg aaatcaaaag aacatggttt agagtatatc
    29341 tggcaaggtg atccagcgta ttggggcaga catgcaccgg ttttattccc ttttgttgga
    29401 cgtttaaacg atgatcagta tgtttatcaa gggaaaacat atcaaatggg gcaacacgga
    29461 tttgctcggg atatggattt tgaagtcatt gaacatggac aagaaatggc tagtttcatc
    29521 ttaaggagta cgccggagac attagaaaag tatccatttg attttgaatt agtgatcagc
    29581 tatgaattag gaggagacgg catcacggtt cattatcaag tggcaaatac cggtgaaaaa
    29641 gaaatgttct tttctatcgg tggacatcct gctttcaatg tacctcttga agaaggattg
    29701 tcatttgaag atttctatct ggcattttct ccattgaaat caagattacg cctaccattg
    29761 aaaggcccat tcatcgatat ggatcaaaag acgttaggtc agacaaatac gaatctggct
    29821 ttgaatcgtg aactttttga gcaagatgcc ttggtttttg aaacaagggg tctaaatgcg
    29881 tacgccattc gaagtgaaaa atcttcccat agcgtaactt taagctataa agatatgcct
    29941 tatgtaggga tctggtctcc ttatccaaaa gaagcgcctt tcgtttgtat cgaaccgtgg
    30001 tgcggaatcg ctgacacggt gaacagtagt ggaaacttga tggaaaaagt agggatcaat
    30061 caactaggtg cccatgaaat cttcaagaca aaatattcca tcacagtgaa gtaagaggtt
    30121 gtgaccgaga agttagcagg gaacaccgtt taccaaggtg tgtaaaaaag ctatcctgta
    30181 agtaataagg gagtgtgaca tcgatttgtc acactcccgt tttatctctt tggaatgaaa
    30241 aagtatcagg attttttctt gctgctattc aaaccaaacg ggattcgact ttcagtatgg
    30301 tttctgatac gcttgatatt gtctttatgc cgataaaaga taaaggaaga aactaaaaag
    30361 gcaatgatcg tcagtaacca attgggctta gccaaaatca caggagctac ataaggaagg
    30421 acgatcgtag ataaagtgat caatactgca ctgatcatac tgctcaaact caccatactt
    30481 gtacaaaata aactaacgat aaagatgata caagaataaa caaaaaatac aggattaaat
    30541 cctaaaagca ttcctgcact tgtcgcaaca gcttttcctc ctttgaaccc agcaaaaatc
    30601 ggaaatgtat ggccaagaat ggcgcatacc ccaaaccaaa gagggttaat cccagaaagg
    30661 tggaagatca tcggcaaaca agtagccaat gtacctttta aaatatccat aagcaggaca
    30721 acaatcccgg ctgttttgcc taatacacga aatgtattgg tcgttccagt attaccgctc
    30781 ccgtgttgtc ggatatcttt tttgaaaaac aatttgccaa tccagacacc ggaaggaata
    30841 gaacctaaaa gatatgctaa aataagtaat aagatcaatt tcatttttta ccctctttca
    30901 agttgaaaac tatcctttat tttagcatga ataggtaaca ggaacaattg aaaaaatgaa
    30961 agatacaagt ataatagatg gaataaaaag aaaagcaagg ggtggcagaa atgtctgtaa
    31021 aaaatccaac acaagaaacg attttcaact atttggaaga agcaaaaaat attgccgtcg
    31081 taggcttgag caataaacca gaacgaacaa gttacatggt tgcacaggta ttgcaagaca
    31141 atggatataa aatcatacca gtaaatccat tattggctgg tgaagaaatt ctaggcgaga
    31201 aagtctatgc gaatttgaca gaaatcgatg atccaatcga tatcgtagat gtatttagac
    31261 ggagtgaatt tttacctgaa atagcaggtg attttttgaa aactgatgct aaagtgttct
    31321 gggcacaatt agggattgaa aacaaagaag cagctgagat gctaagaaaa gcaggacgta
    31381 cagatatcgt aatggatcgt tgtattaaga ttgaacttgg taagttgaaa gaaaaccaaa
    31441 aataaaaatg accacaaaga agagatgatc gatagagggg aatgtcgaaa aagcggttag
    31501 gagataatta aaattgattt ctcgtctacc ctcttttttt tcacgacctt ttctagtatg
    31561 ataatcgtgg tgcggttttg ccgcaaagta ttattgaagg agcgtttgcc ttggcaaaaa
    31621 aagtaaacaa cgaatacaat gactcgtcca tccaagtatt ggaaggatta gaggcagtta
    31681 gaaaaagacc agggatgtac attggatcca ctgacagccg aggcttgcat catttagtct
    31741 atgaaatcgt cgataatgca gttgacgaag cattatcagg ttatggcagt gagattgatg
    31801 tgaccatcca tgaagacaat agtataactg ttgcagatag cggacgtggg atgcctgtag
    31861 gaatgcatgc ttccggaata ccaacagttg aagtgatttt tactgtgctg catgctggcg
    31921 gaaagtttgg tcaaggaggg tacaaaactt ctggtggact gcacggtgta ggagccagtg
    31981 tggtaaatgc cttatcgaaa tggctaattg taacgatcgt tagagatggc gtagagtatc
    32041 agcagaaatt taaaaacggc ggtaaacctg acggtacttt gaaaaagata ggaaaaacaa
    32101 aaaaagcaaa cgggacgact gtccattttt taccagatga tacaatattc agtacaacga
    32161 aattttcata tgaaatttta gccgaacggt taagagaatc tgcctttctt ctaaaaggcg
    32221 ttaaaatctc tctttctgat cttcgtggag aagaaccagt caaggaaatt tttcattacg
    32281 aagaaggaat caaagaattt gttgattatc tgaatgaaga aaaagataca ttgacaccag
    32341 ttgtttattt ttcaggagaa aaagaaggta tcgaagtaga ggtcgcttat caatacaatg
    32401 acggttattc agaaaatgtt ttatcttttg tcaataacgt tcggacaaaa gatgggggaa
    32461 cccatgaagc tggtatgaaa gcggcgatga cgaaatctta taatgaatat gcgagaaaag
    32521 ttggtttgct gaaagaacgg gacaagaatc tggaaggtag tgatttcaga gaagggttag
    32581 ctgctgtact ttctatccgt gtacctgaaa atcttctgca atttgaaggg caaacaaaag
    32641 aaaaacttgg tacgccagtt gctcgtaccg tagtagataa cgtcatcagt gaacaaatgg
    32701 gcttttattt gcaggaaaat agcgaaatga gccagatgtt ggtccgtaaa gcaatcaaag
    32761 ccagagaagc gagagaagca gcacgtaaag ccagagaaga aagccgaaat gggaagaagc
    32821 gtaaaaaagg cgaatctctt ctttcaggaa aattgacacc cgcacaatcc cgaaacccta
    32881 agaaaaatga attgtattta gtcgaagggg attctgctgg cggatctgct aaacaaggaa
    32941 gagacagaaa gttccaagca attctacctt tacgaggaaa agtcatcaat accgaaaaag
    33001 ctaaaatgca agatatcttg aaaaatgaag aaatcaatac gatgatctat acgattggtg
    33061 caggagtcgg tcctgagttt tctatcgaag actgtaatta cgacaaagta atcatcatga
    33121 ccgatgcgga tacagacggc gcccatattc aagtattact gcttactttc ttttatcgtt
    33181 atatgaaacc gctgattgaa gctgggaaag tatatatcgc gttaccgcct ttatataaag
    33241 tatccaaagg acaaggaaag aagcaagtca ttgaatatgc gtggacagat gacgaattgg
    33301 cagcaatgat taaaaaagtc ggcaaaggat atatgctgca gcgatataaa ggacttggag
    33361 agatgaatgc ggaacaattg tgggaaacaa cgatggatcc gacttcccgt acgttgatcc
    33421 gcgtccgtat cgatgatgct gcgcaagctg aacgtcgagt aaccacactg atgggtgaca
    33481 aagtagaacc tcgaagaaaa tggatcgaaa atcacgtgca atttacgctc gaagaagatg
    33541 gcagtatctt agataaaaaa gaggatactg aaatctctcc ttcagtttct aatgatttat
    33601 tagatgaaga acgagcagat aaaaatgaaa acaatcagtt atttgaagta gaataggagg
    33661 tcacctgatg gaaaatcgac aagaagtaca agaattaact ttagaagaag tgatgggtga
    33721 ccgcttcgga cgttattcca aatatattat ccaagaacgt gcactgcctg atatccgtga
    33781 tggattgaag ccagtgcaac gccggatatt atttgccatg aacaaagatg gcaatacgta
    33841 tgacaaagga ttccgtaaat cagcaaaatc tgtcggaaat atcatgggga attatcatcc
    33901 tcatggtgac atcagtattt atgaagcgat ggtccgcatg agccaagact ggaagttgcg
    33961 ggaagtactg atcgaaatgc acgggaataa cgggagtatg gacggtgatc cacctgctgc
    34021 gatgcgttat actgaagcca gattatccaa gttaagtgga gagatgctag cagatatcga
    34081 gaaagaaaca gtcgatctcg tgtggaattt tgatgataca gaaaaagaac caacagtcct
    34141 tccagctcga tacccaaacc ttctcgtcaa tggatcgaca ggtatatctg ctggatatgc
    34201 aacagaaatc ccgactcata acttagctga agtgatcgat ggcacaatct atatgatcga
    34261 tcatccacaa gcgagccttg aaaaattgat ggaatatatt cctggacctg actttccaac
    34321 aggagggatc ttgcaaggaa aagatgaaat caaaaaagct tatgaaacag gacgaggaaa
    34381 agttattctt cgttcgaaaa caaagataga ggcaatgaag ggtaataaac agcaaatcgt
    34441 gatcacagaa atcccatatg aagtaaataa agcgaccttg gtgaaaaaaa tggatgagat
    34501 ccgtttgaat aagaaaatcg atggaatagc tgaagtacga gatgaaagtg atagaacagg
    34561 tctgcaaatt gtcgtcgaat tgaaaaaaga cgccaatgct caaggaattt tgaattattt
    34621 gttcaaaaac actgagctac agatcaatta caatttcaat atggtcgcta tcgaccatat
    34681 gactccgcat caagttggac tgaaagacat tttaagaagt tatatcgagc atcgaaagca
    34741 agtcataaca aaacgtagtc aattcgattt agccaaagct caaaaaagac agcatatcgt
    34801 agaaggattg atgaaagctt tatcgattct ggatgaagta atcgcaacga ttcgtgaaag
    34861 taaagacaaa aaagacgcca aaaagaattt agtcgacgtc tttcaattta cagaagaaca
    34921 agcagaagca attgtcacat tgcaattata ccgtttgacg aacacggata tcacagagct
    34981 tcaaaaggaa tccgaaagct tgattgcgca aatcacagag ttgaataaaa tcctttcaaa
    35041 tgacaaagag cttttctctg ttatgaaaaa agaattgcga gaagtgaaaa aaaattattc
    35101 ttccgctcgt ctaacgacaa tcgaagacga aatcgaagaa atcaaaattg atacgcaagt
    35161 cttagtggca caagaagacg taattgtcag tgtgacgcga gaaggctatg tgaagcgaac
    35221 aagccttcgt tcttatagtg cttccaaacc agaagaaatc gggatgcgag aaggcgacta
    35281 cttgctatac tcaggtgaat tgagtacatt ggaccatgtt cttctgatca caaataaagc
    35341 aaatgtgatc taccgccctg tccatgaact acccgatttg aaatggaaag atgctggtga
    35401 gcacatttct caaacaatct ccaatctgtc tgtagacgaa tcgattttag ctgttttccc
    35461 atatcaaaaa attcaagcag agaaaacatt tgtattcatc agcaagaatg gattgatcaa
    35521 gcaaacacga atgacagagt tcgaaccatg gcgcacctat aagagccgtc cgctcagctg
    35581 tatgaagcta aaggcggaag aagatgaact gattgctgtg tatctgaaag aagatcagcc
    35641 aggcttagat gttttcttag taacgcatca aggaatgggt ttgcgctatc ctttaacaga
    35701 tgttcccgtt gttggagcaa aggcagctgg agtgaagtct atgaatttga aagatggaga
    35761 taggattatc aacgggctgc ttgtgttagc agaaggtgat acgccgatcg taatcgttac
    35821 tcagcgagga gctgttaaac gcatgcttgc tcaagaaatc agccaaactt cacgtgcgaa
    35881 gcggggagtg acggtcatgc gtgagctgaa aaaaaatccg caccgtatta tctatatgtc
    35941 ggaaggaaga tcaaaagaaa taaccttgat gaatcaaaaa gggcagcagt taacgattga
    36001 cccaactgat ttccctatag gtgatcgaac atcgaatgga tcatttgcga tggatgagaa
    36061 aaaaggtgga gaagtcatcg aagttatcga tgctcctgag attttcatcg agtcgtaact
    36121 gttgtagtat tttaatgaag agacgccatc tgtattaata caggtggcgt ctctttttca
    36181 ttcattttta ataaatcctt atacgtttgc aaaaaaagat gaaagtgttc acaatgctta
    36241 aatgttggta tgtcaacgtt gatttaaata tatgtaaata aaacataaaa attgttaaat
    36301 aaaaaacaag aaaacccttg caaagatagg gtgctgtgtt atactaatca cgtaaaaact
    36361 gttacataaa acagaaattt aggaggtcca tacaatggag caatggaatg gatttaaagg
    36421 taccaaatgg aaagaaggcg tagacactag agactttatt caaaataact acactgaata
    36481 tcgcggtgat gacagctttt tggaaggccc aacagaagca acagaaaaat tatgggatga
    36541 attgcaaaag ttaaatgata tccaattcga gcgtaacggt gtctatgata tggacacaga
    36601 aatcgtatca actattactt cacacgatgc aggctatttg gataaagatt tggaaaaaat
    36661 cgtcggtcta cagacagaca aacctttgaa acaagcattc atgccgttcg gcggaatcaa
    36721 tatggctaac aatgcgctaa aaagcaatgg ctatacacca aacgatgaat tgacacatat
    36781 tttcactgac tggcgcaaaa cacataatca aggtgtattt gacgcttata ctgctgaaat
    36841 gcgtgctgct cgtaaaaaca aaatcattac agggcttcca gacgcttacg gtcgcggacg
    36901 tatcatcggt gactatcgtc gtgtggcatt gtatggaatc gactatttga tggaacaaaa
    36961 gaaaaaagat catgatatga ctggttatca tacaatgagt gaagaagtga ttcgtttacg
    37021 tgaagaaatc actgaacaat atcgtgcatt agcgcaaatg aaagaaatgg ctgcgaaata
    37081 tggctatgat atttctaaac cagctgcaaa tgcaaaagaa gctgtccaat ggctatactt
    37141 cggatattta gcagcaatca aatcacaaaa tggtgctgcg atgtcaatcg gacgtatctc
    37201 agcattcctt gatatctata tccaacgtga tttggataat ggagtaatca cagaaaaaga
    37261 agcacaagaa ttgatcgacc acttagtaat gaaattacgt atggtcaaat tcgcgcgtac
    37321 acctgaatat aaccaattat tctcaggatt ccctatctgg gctactttat ccattgcagg
    37381 tatgggatta gatggtcgtt cattagttac aaagaatgat ttccgtctgc ttcatacatt
    37441 aacaaatatg ggaccttcac cagaaccaaa cttgactgtt ttgtattctg aacaccttcc
    37501 agaaggattc agaacatatg ctagcagaat cgctatcgaa agttcttcga ttcaattcga
    37561 aaatgataat cagcttcgtg aacaatgggg ttctgatgat tgtgcgattg cttgctgtgt
    37621 atcaggaaca gttgtcggaa aagacatgca attctttggc gctcgtgcta acttggctaa
    37681 aacactatta tatgccatca atggcggagt cgatgaagtg actggcgccc aagttggacc
    37741 agaatatcgt ccaatcacat cagaaatact agactttgaa gaagtgaaac ataacttcat
    37801 gaatatgatg gattggttag cagaactata tgtcaatacg ttgaacatca ttcattatat
    37861 gcatgataaa tattcttatg aagcagctca gctggctttg atggattctg acttgcaacg
    37921 cacatttgct acaggtattg ctgggatctc tcatgcggca gacagcttgt cagcgatcaa
    37981 atatgcaaaa gtaaaagcaa tccgtaatga aaaaggaata gcagttgatt ttgaagtgga
    38041 tggcgacttc cctaaatacg gaaatgatga tgaccgtgca gatgaattag tttcatggat
    38101 cttggaatac ttcatgggac aaatcaaacg tcataaaact taccgcaact caaaaccaac
    38161 aacttcatta ttgacgatta cttcaaatgt tgtttacggt aaaaatacag gaaatactcc
    38221 tgatggccgt gaagctggaa aaccacttgc gccaggagca aatccaagtt acaatgcgga
    38281 acaaagtggg ttattagcta gcctgaactc aacagctaaa atgaattacg gctgtgcatt
    38341 ggatggaatt tcaaataccc aaacaatcaa tccttcaggt cttggaaaag aacaagatac
    38401 aagaatcgaa aacttgcgta atgtcttaga tggatacttc tcaaaaggag cttatcattt
    38461 gaatgtcaat gtattcagta atgatttatt gcgtgatgca atggaaaatc caatgaaata
    38521 tccgaacttg acgatccggg tatctggtta tgcagttaaa ttccgtgact tgacaagaga
    38581 acaacaatta gatgtcttga tgagaacttc acacgacaga atgtaaaaag ttcgtgaaaa
    38641 aagtttttcg acttagcgtc gaaaggacgt tgaatagcca tcgcatcaaa atcgaataat
    38701 cagtatgctt atttgaaaga aacgatttac aggggcagga cttgtatgtt ccgtccctgt
    38761 aaattttaca cataacgaag cggcaattgc gaaaaatttt gttcagaaag cttcgcttcg
    38821 acagctaact tgtacttaaa atgaaatcaa agaaaagatg tgaacttaaa tggaagaaaa
    38881 aacaatcggc tatgttcatt ctatcgaaac tttcggttca gtagacggac ctggactgcg
    38941 ctttgtcgtg tttatgcaag gatgccgcat gcgttgccaa ttttgtcaca atccagatac
    39001 ttggaatatt ggcggaggga aagaatacac agcagatgaa cttttagata aagcagaacg
    39061 cttcagacct tactggggag ataaaggtgg tattactgtt agtggtggag aacctctatt
    39121 gcagatcgat tttttgatcg aactatttaa aaaagcaaaa gagcggaaga tgcatactac
    39181 attggataca tgcggaaaac cttttacgta tgaagaacct ttcttttcac gttttcaaga
    39241 attgatgaag tatacagatt tactgttatt tgacatcaaa cacatcgata atgaagagca
    39301 taaaaaacta acgcattggg acaatgaaaa tattttagaa atggctcaat atttgtcaaa
    39361 aatcaacaaa ccggtttgga ttcgccatgt actagttcct gagcgaagtg attatgatga
    39421 atatttgatc cgactagaca actttattca aaccttgtca aatgtagaca gagtagagat
    39481 tcttccttat catacgatgg gaaaatacaa gtgggaaaca cttggtttga aatatccatt
    39541 agaagggatc gaaccaccta caaaagaacg tgtcgaaaat gctaaacgat tgcttcatac
    39601 agaagagtat acaaaatatt taacgcgata ggtcgcatcg gaaagaagat aagtattgct
    39661 tctttccgtt tttttgctat tattaaatag gagaaatcac aaaggagcga atgacatgtc
    39721 aaaaatttta gtttttggtc accaaaatcc agatacagat gcaatcgggg cagccattgc
    39781 gttttcacac ttgcaaaatg aattaggtaa agaaacagaa gcagttgctc taggtacacc
    39841 taatgaagaa acacaatacg cattagacca ctttcagcta tctgcaccac gagtagtaga
    39901 gtcagctaaa gcagaaaatg cagatgtcat gcttgtggat cataatgaat tccaacaaag
    39961 tatttcagat atcagcgaag taaatatttt agctgtagta gaccaccatc gtattgcaaa
    40021 ctttgaaaca gctaatccat tgtactatcg tgcagaacca gttggatgta caagtacgat
    40081 tattttaaaa ctatataaag aaaaccaagt aacaattcct aaagaaatcg caggaatcat
    40141 gctctcagct atcatttcag atacattgtt gttcaaatca ccaacatgta cgcctgaaga
    40201 tgaagcagct gcaaaagaac ttgcagcaat cgctgaagtc gatctaaaca cttatggact
    40261 tgaaatgttg aaagcaggaa caaatctaag tgataaatca gctgcggttc ttcttgattt
    40321 ggatgcaaaa agtttcccaa tgggcagttc caacgttcgt atcgctcaag tcaatacagt
    40381 ggaccttaat gaagtgatgg atcgacaagc agagctagaa gcagcaatgg aagatgaaat
    40441 gaaagcaaat ggctacgatc tgttcgtatt agttgtcaca aacatcttag acagtgattc
    40501 agaattactt gttgctggta aaggaaaaga aaaagtagaa gaagctttcc aaacaacttt
    40561 gaccaacaac cgtgctttgc ttaaaggtgt cgtttcacgt aaaaaacaag tcgtacctca
    40621 attgacggct gtatttagct aatcaaatgg tagtatgaag cattcaaaat gaatggataa
    40681 gcgattgata taaaaagaaa catagaacat actaaaggcc gaagaaatgg aggagaataa
    40741 cagtcaatta tgactcttgt tcttcctcct ttttacgtaa aagcctttta agtaaaataa
    40801 aacggataga aaagagaaca tatatgaact attattcaaa aaataaggaa aacttttatc
    40861 aaaaactgac cgatgatccg cttttttctt cattgaccga ttatctatat gaacatcgag
    40921 aacaagaaac gattctaaga gaattgaaaa aagaattttc gcaaaataaa ttttcccatt
    40981 ttcttgattt attgatcgat gcaggattaa tcaagaggga agaacgaaga tatcatttga
    41041 actttccaat atttgatcct aaagattact tgcaacaagc cacttcggct gctgaaacca
    41101 tagctgaaca attgaagaga ctctctgttg atgaacaaaa attagcgatg ggagaagtta
    41161 tttgggcgta ttgtttcgaa gatgaacgga aagaagcgta tttttatgga gtaagaaaca
    41221 gccgagagac agaattgctg aggacaactg caggaaatga gaagtaccgt tttatcacac
    41281 tttcctctat agaacacttc ccgcttactt tggctaatta cttttttgta cagaagaatc
    41341 agcttcctgt aacgaaggca ttcaaagaat tagccgaact tattggagac gtaaatgaat
    41401 cgtacttttt tgatcaaata gaagttatcg ttgacaggat acgtaagaat aaatataaaa
    41461 atcgccggcc tagtattttc catcagtctc tacttgtgac gaatactata aaggaagaag
    41521 aatcattcac attagaatta cctattgtcg aaaaaaacaa ttttgagatt gaattaccaa
    41581 cattggatcc ttcattgaca atggaggaaa tggcctttct taaacgacaa atcttttctg
    41641 agctgagcaa gaaatttata ccgcatgcat tttcttatat caaagaatat ggaacagttt
    41701 tagtgagtaa aacctaagag agcagtaagc aaaaattata ctgactcttg caggaggagc
    41761 ctttctcttc ctttatggtt aaaagaatta tttgagtatt ttgcctatct accacctatt
    41821 agattcacta catggtctgg aaacaaagga atgcaaaaaa atggtgagaa atgtggaatg
    41881 acaaaggaag tagtgataag aaaagttaga tttttaaata atcaatatta tgattcagtc
    41941 aagtatggca ttttatggga agaactagct gattagatta ggaagtccat ttgataatcc
    42001 agaatcacta agaaacgaat ggcgagtcat taataattta tccaatcttg ggttattctt
    42061 ttagattgaa gtgtttaaaa ctaaaaaagc atttatgaag tcgtaatagt caggcttcaa
    42121 aatgcttttt attttgtttg ttttttcttt gccacataaa tacacctaga ctgacgatga
    42181 agagcatatc caacagattt cctgcgactt ggatcgtcga agggttggtc agtggcatta
    42241 aagcaaggac aaaaaaggaa aacaagctgt aaataaaaca ggtgacagga actaatcgaa
    42301 agaagagcgg acatttcaat tggctaaaaa tgagtgaaaa aataaaataa gtaaaaatgg
    42361 ataaaatcac gactaaacca ttcatgataa agaagaaaag cgtattgtga ttaaacgaat
    42421 aaaaaagaat tgctaaaaaa gaaaacgttt taaatgcaat caatacgctt gaagcttcgt
    42481 ttaacgtacc aggatgtcga tgaaaaaaat aggcaccgaa ataaacagaa aacagtaagc
    42541 cgcaaagaga agacaaaatc aaaaaaaacg gattttcttc ggcttctgtg atatcagaat
    42601 gatccaaaag caaccagcct aatgcactag aaggcgcatg tgaggtctta aggtatgaat
    42661 aacatagaaa aaataagatc gtcaaagttg caaaaaaaga gcctaaatgt aaaaaattag
    42721 tggttctacg ttgaatttcc ataatatctc caaattaaat tgataagtat ataaagtata
    42781 ataacaaatt gatgagtata tgtcgatgtt ttttaatcaa aataataaat aaaaactgtc
    42841 taacatttaa aatttaattt agatattaga cagtttttaa gtttgtgagt tattttcctt
    42901 gtcgttttct cactttttta gtccagaaac cacctgaaat atattttggc tcataagaaa
    42961 tgataaaagc acgctcttcg atttctttga tcaggcgata cagttcacgt tcgctttttc
    43021 taggagaaag tatttcgaga actagccgct caccttccag ccccattgca gaagtctgtg
    43081 tcacaccata accgtgttct ctcagtatac ccggcaaact tttatcttct gcgctatttg
    43141 ctggcaaaat cgttgtgacc atgatgtatc ctaatgccaa tttgtcttca atcaaaattc
    43201 cgacactgat acctactgcg taacctaacg catagacaaa taaattcagt ggattatcta
    43261 aacgatctaa aacaagggat aagccgacga tataaatcgt gatctcgacc atactgacaa
    43321 gtggagcaat cagtcgatag cctttcattg tcaacatgaa acgtaacgtg ttcagagtga
    43381 tataagcaaa attaatgagg aagatcatcc ccaacatttt tggatcaatc atttgtaaaa
    43441 ctcctttcat ttatataaca acaatatcaa aaaaaatcgt aagtgaagaa aaattgaaac
    43501 tttatacata caaaaaaatg ataaaatgat tataatagaa ttataaagat aggttaggtg
    43561 attaaaatga aaacggtcaa tcgtgtgttt tgtgccagcc acgtgctaag tctccttctc
    43621 agtatatact taggtgtcta ttcgattcaa cagccaattg aggtagagaa cattgttttt
    43681 cagatgtcgc tgacagatgg tttaatttta agcgtttttt tctttttgat actgtttatt
    43741 ggtaatattt tcggtagcgt tgccagtttt ttgaattttt ctatttatcc actcctttcg
    43801 ctagcattag gagtggtggg actttgttct ctgtgcttat ttcccgagcc attcagtcct
    43861 gcatttatat tatttggtac actgaacctg ttccagacaa ctgttggagc atggttgcta
    43921 tggcgatcag gaaatttaat gaaaataggt gagtaacaat tgaatccaat tatattgaaa
    43981 cgttctgtcc atcatattcc agtgttagaa gttgttctga aagaattaag agaggaacgt
    44041 attcccgttg tcatctatta tcacggatgg cagacaagta aggagttagt tttgacgcaa
    44101 ggaagaaaaa ttgcgcagca gggcattcgt gtgatcctgc cagatgcgat gaatcatggg
    44161 gagcgcaaac agccggtttc ttctattcca tcctatacat tttgggatag tatctacgga
    44221 aatctgtttg aatttgacac acttatcaag catttagaaa aaagaggtct tctacatgat
    44281 cagcttgcag ttggcggggt ttcgatgggg ggaatgacaa catgcgcctt gttggctaaa
    44341 catcctcata tagtagcggg cgtgtgtttg atgggttccc ctgcaccttt ggaatatgga
    44401 aaagaaatcg taaggcgcgc atcggaatat aattatgtcg taccaaaaga ctattttgat
    44461 ttgatttcat gggttaagag ctatgatttg tcattgcagc cggaaaagtt agctggacgt
    44521 cctctgttct tttggcatgg acaagctgac gaaaaaatcc cttatataca aacggaacga
    44581 tttgtagaaa aaaatcggca taagtcttac ggaaaagaaa ttgtttttcg ttcctcaaaa
    44641 acacagcgac atatggtaca aataccacta atggaagaag cttccacttt tttagcaaaa
    44701 aatttgataa aaaagtataa ataattgaaa cggaaaatca ctcatgacga tagaggattt
    44761 tccgtttttt attttgggct ataataaact ctgttaggaa aatttggtat aattgatagt
    44821 aagaatgaca acatgttaga aaggaagaga gcatgcccac tttagcagat gttgcaaaac
    44881 gtgccaatgt ttcaaaaatg acggtctctc gagtcatcaa tcatccggaa caggtgactg
    44941 acgaattgaa agagttagtt ttctcagcaa tggctgaact ggattaccgt ccaaatattg
    45001 ctgcaaaagc acttgtcacg aatcggtcgc agatcatcaa attatttata ctggaagaaa
    45061 tcgacacaac tgagccctat tacatgaatt tgctgatggg aatcgctaaa cggatcggta
    45121 aagcgcatta ttctctccaa ttagttacaa atgatgcctt cgacgtcggt tcttgtgatg
    45181 gatacatcat cacaggtgtc agaaaaaaag acttcgattg gatcgaccgt ttggaaaaac
    45241 cagttgtctt gtttggggaa aattctgaag gatatgatta tgtagacagc gataatgaat
    45301 atggtacagc aaaagcaacg caatatgcct tagaaagaga ttatcaaacg attatttata
    45361 tcggtatcga agtggacgag ccttttgaaa tttcaaggga aactggttat ttatctgtga
    45421 tgaaggaagt tgatcttcct agtaaaatct tgcggtttcc aaatcattcg acagaagtag
    45481 aaagatatat gacagaaaac tgggcagatt ttacagataa aacttgtttt gtatgtagtt
    45541 cagatcggct agcactagga gcagtaagag ggattataaa tgctggagga cacttgcccg
    45601 aagaatttgg tgtgattgga tttgatgggg tatttttaga ccaaatcagt tcacctaaat
    45661 tgacaacgat caagcaagat attatacgta tgggtgaagt atgtggagaa atgttgttaa
    45721 aaaaaataga agaaaaaggg gcgagtcaag gttatcgtcg tttttttcct gaactagtta
    45781 tcagagagac aacgaattaa gtcttattac tatatatata tttatgaaat tcatcgctat
    45841 tttcttaaaa taatcagcgc attgctactg aaaacaatga atctgtgcta ttattgagaa
    45901 aagttccatt tttgagaagg atggtttgaa tgaaagaaat cagacgaaaa catttccgtt
    45961 ttcctgcgta cgatgatgag ttaggcgtaa aattaaccaa cgacaagaag cgagtattat
    46021 ttgacggaca agaagatctt ttgactgaac agaatcagtc cccgtttgaa cagatgaaag
    46081 aatttcattt cacgaacacg aacaccgaga aaatccgtcg caagcgtcgt gcaacaaatg
    46141 gattgaagtc agctccgcgt aaggaaaatt tggaaaagca taaaggaaaa ttaccggatt
    46201 ataccggcca ttaccaatca gaaatcacat cgacaggacg aaaaaaactt tttggtgatt
    46261 cctctcgttc tgtcagacaa agtgaaacaa ggacagagtc caagcatact acacgaaacg
    46321 catctgttga cacgaaggtg cgggagcgtt cttattttgt tcctaaatat gtacccgcat
    46381 cgattatccc agaccctaga gaaagcaaaa tttctgagga tcatttaatc gaatcgatga
    46441 aaaaaacgga tgactcttat ctgttgttcg atacagaacc gacgccgtat caagaaaaaa
    46501 gaaatggtga gccgtctgta cgaacattca atcgaacaaa aacgttagag gaaacaaagc
    46561 agtcagaaga aaaaaaatcg aaaaaaagcc atggtatctt agaacgctca ttacaaggat
    46621 tgatcgatga tcaaggaaac tctttgggag aaaatagcta ttttaaataa gtgatataca
    46681 aatttatatt cggctacagt tggaaaggaa acgctgcggc gtttccttat tttatactct
    46741 atccgaaagt ttatatcgta tcctcaaatt tttttgagtt taagcgaatt ttttctccca
    46801 ataagtaaga aaataatgg
//
LOCUS       DAZKPE010000014        44878 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000014 DAZKPE010000000
VERSION     DAZKPE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.014"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            163..555
                     /locus_tag="ACG930_000902"
     CDS             163..555
                     /locus_tag="ACG930_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0518078.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            583..1923
                     /gene="glnA"
                     /locus_tag="ACG930_000903"
     CDS             583..1923
                     /gene="glnA"
                     /locus_tag="ACG930_000903"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFQ0518079.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2649..2894
                     /locus_tag="ACG930_000904"
     CDS             2649..2894
                     /locus_tag="ACG930_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518080.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3116..4726
                     /locus_tag="ACG930_000905"
     CDS             3116..4726
                     /locus_tag="ACG930_000905"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFQ0518081.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4703..4915)
                     /locus_tag="ACG930_000906"
     CDS             complement(4703..4915)
                     /locus_tag="ACG930_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518082.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5018..5887
                     /locus_tag="ACG930_000907"
     CDS             5018..5887
                     /locus_tag="ACG930_000907"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFQ0518083.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6052..7323
                     /locus_tag="ACG930_000908"
     CDS             6052..7323
                     /locus_tag="ACG930_000908"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFQ0518084.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7320..8615
                     /gene="rho"
                     /locus_tag="ACG930_000909"
     CDS             7320..8615
                     /gene="rho"
                     /locus_tag="ACG930_000909"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFQ0518085.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8714..8977
                     /locus_tag="ACG930_000910"
     CDS             8714..8977
                     /locus_tag="ACG930_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFQ0518086.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9422..9871
                     /locus_tag="ACG930_000911"
     CDS             9422..9871
                     /locus_tag="ACG930_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0518087.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9928..11346
                     /locus_tag="ACG930_000912"
     CDS             9928..11346
                     /locus_tag="ACG930_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFQ0518088.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11346..12206
                     /locus_tag="ACG930_000913"
     CDS             11346..12206
                     /locus_tag="ACG930_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFQ0518089.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12380..13153
                     /locus_tag="ACG930_000914"
     CDS             12380..13153
                     /locus_tag="ACG930_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0518090.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13300..13665
                     /locus_tag="ACG930_000915"
     CDS             13300..13665
                     /locus_tag="ACG930_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFQ0518091.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13813..15021)
                     /locus_tag="ACG930_000916"
     CDS             complement(13813..15021)
                     /locus_tag="ACG930_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0518092.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15040..15318)
                     /locus_tag="ACG930_000917"
     CDS             complement(15040..15318)
                     /locus_tag="ACG930_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518093.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15511..16167
                     /locus_tag="ACG930_000918"
     CDS             15511..16167
                     /locus_tag="ACG930_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0518094.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16609..17406)
                     /locus_tag="ACG930_000919"
     CDS             complement(16609..17406)
                     /locus_tag="ACG930_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFQ0518095.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17403..18587)
                     /locus_tag="ACG930_000920"
     CDS             complement(17403..18587)
                     /locus_tag="ACG930_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFQ0518096.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18612..19859)
                     /locus_tag="ACG930_000921"
     CDS             complement(18612..19859)
                     /locus_tag="ACG930_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFQ0518097.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20074..21819
                     /gene="dnaX"
                     /locus_tag="ACG930_000922"
     CDS             20074..21819
                     /gene="dnaX"
                     /locus_tag="ACG930_000922"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFQ0518098.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21839..22153
                     /locus_tag="ACG930_000923"
     CDS             21839..22153
                     /locus_tag="ACG930_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFQ0518099.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22178..22774
                     /gene="recR"
                     /locus_tag="ACG930_000924"
     CDS             22178..22774
                     /gene="recR"
                     /locus_tag="ACG930_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFQ0518100.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22838..23482
                     /gene="tmk"
                     /locus_tag="ACG930_000925"
     CDS             22838..23482
                     /gene="tmk"
                     /locus_tag="ACG930_000925"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFQ0518101.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23497..23826
                     /locus_tag="ACG930_000926"
     CDS             23497..23826
                     /locus_tag="ACG930_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFQ0518102.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23840..24778
                     /gene="holB"
                     /locus_tag="ACG930_000927"
     CDS             23840..24778
                     /gene="holB"
                     /locus_tag="ACG930_000927"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFQ0518103.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24814..25638
                     /locus_tag="ACG930_000928"
     CDS             24814..25638
                     /locus_tag="ACG930_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFQ0518104.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25631..25978
                     /locus_tag="ACG930_000929"
     CDS             25631..25978
                     /locus_tag="ACG930_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFQ0518105.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26047..26919
                     /gene="rsmI"
                     /locus_tag="ACG930_000930"
     CDS             26047..26919
                     /gene="rsmI"
                     /locus_tag="ACG930_000930"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFQ0518106.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27028..28149
                     /gene="dinB"
                     /locus_tag="ACG930_000931"
     CDS             27028..28149
                     /gene="dinB"
                     /locus_tag="ACG930_000931"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFQ0518107.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28203..28805)
                     /gene="nrdG"
                     /locus_tag="ACG930_000932"
     CDS             complement(28203..28805)
                     /gene="nrdG"
                     /locus_tag="ACG930_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFQ0518108.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29120..31309)
                     /gene="nrdD"
                     /locus_tag="ACG930_000933"
     CDS             complement(29120..31309)
                     /gene="nrdD"
                     /locus_tag="ACG930_000933"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFQ0518109.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31635..32402
                     /locus_tag="ACG930_000934"
     CDS             31635..32402
                     /locus_tag="ACG930_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518110.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32392..34434
                     /locus_tag="ACG930_000935"
     CDS             32392..34434
                     /locus_tag="ACG930_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518111.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34715..34864
                     /locus_tag="ACG930_000936"
     CDS             34715..34864
                     /locus_tag="ACG930_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFQ0518112.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34875..36389
                     /gene="dltA"
                     /locus_tag="ACG930_000937"
     CDS             34875..36389
                     /gene="dltA"
                     /locus_tag="ACG930_000937"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFQ0518113.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36386..37591
                     /gene="dltB"
                     /locus_tag="ACG930_000938"
     CDS             36386..37591
                     /gene="dltB"
                     /locus_tag="ACG930_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFQ0518114.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37636..37869
                     /gene="dltC"
                     /locus_tag="ACG930_000939"
     CDS             37636..37869
                     /gene="dltC"
                     /locus_tag="ACG930_000939"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFQ0518115.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37872..39140
                     /gene="dltD"
                     /locus_tag="ACG930_000940"
     CDS             37872..39140
                     /gene="dltD"
                     /locus_tag="ACG930_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFQ0518116.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39281..40363
                     /locus_tag="ACG930_000941"
     CDS             39281..40363
                     /locus_tag="ACG930_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFQ0518117.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40363..41166
                     /locus_tag="ACG930_000942"
     CDS             40363..41166
                     /locus_tag="ACG930_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFQ0518118.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41236..41976
                     /locus_tag="ACG930_000943"
     CDS             41236..41976
                     /locus_tag="ACG930_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0518119.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            41987..42991
                     /locus_tag="ACG930_000944"
     CDS             41987..42991
                     /locus_tag="ACG930_000944"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFQ0518120.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43036..>44878)
                     /locus_tag="ACG930_000945"
     CDS             complement(43036..>44878)
                     /locus_tag="ACG930_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518121.1"
                     /translation="SFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSPA
                     DSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLLI
                     KGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNYA
                     GLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLI
                     LLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKKW
                     YGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNRF
                     YVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNTD
                     KDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKNY
                     VEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDDL
                     AQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGITE
                     ELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14417 a         7832 c         9341 g        13288 t
ORIGIN      
        1 atctggtacg aaaatcaact agataccttt tttgtgttct tatttttttg ttattttata
       61 aaaaatagag atctcatgtt agaaaaccta acatatgcag ttgacaatat tttttttaat
      121 tggtacactt tagccaactt ataaaacgaa aggggacgtc tgatgggaga aaaggaattg
      181 cgccgatcta tgtccgtatt tccaattggt acagttatga agctgactga tttgtctgct
      241 cggcaaattc gctattatga agaacaagat ttagttcatc cggaacgaag cgaaggaaac
      301 cgacgtatgt attcgctgaa tgatattgat atgttgcttg agattaaaga ctatctttca
      361 gagggattga atatggctgg gatcaaacgt gtatacgaaa tggcacaggc gaaaaaacaa
      421 gaagcaaaaa acaagaagcc gttgacagat catgacgttc gacaaatttt tcgtgatgag
      481 attttggcgc aaggtgggtt aagcaaaaca ggtcattatc agtcgcaagg attgcaaaga
      541 caattctttg actgaataaa ttaaaaaagg aagagggata ccatggtaaa gaaacagata
      601 acaggtgaag aaatcaaacg aatcattgag gaagaaaacg tacgattttt acgattgatg
      661 ttcacagaca tcttaggtac gatcaaaaat gtagaagttc cagtgagcca gatcgacaaa
      721 gtattagaaa ataaaatgat gtttgacggt tcttcgattg aaggatttgt tcgaattgaa
      781 gaaagcgata tgtatttgta tccagatctc tccacttgga tgatcttccc gtgggaaagt
      841 gctcatggaa aagttgctcg tttaatttgt gatatctata atccggatgg gacaccattt
      901 gccggcgatc ctcgcgggaa tttgaaacga gcattgaaag atatgcgcga ccttggtttt
      961 acctctttca atttaggacc tgaaccagaa ttcttcttat ttaaattaga cgaagacggt
     1021 gggatcacaa cgaccttgaa tgataaaggt ggttattttg attttgcacc aacagattta
     1081 ggtgaaaatt gccgccgtga catcgtgttg gaattagaaa gtctaggctt tgaagtggaa
     1141 gcttcacatc atgaagtagc gccaggacag catgaaattg actttaaata tgcagatgtg
     1201 gtagatgctt gtgataatat ccaaaccttc aagctcgttg tcaaaacgat tgcacgcaag
     1261 catggacttc acgcgacttt catgccgaaa ccgttatttg ggatcaatgg ttctggtatg
     1321 cattgcaata tgtctttgtt caatgatgaa ggaaatgttt tctatgataa agacggtgaa
     1381 ttggaactaa gtgaaacagc ttatcatttc ttaggtggtt tgctgaaaca tgctcgtgcc
     1441 tacacagccg tttgcaatcc aacagtcaat tcttataaac gtctcgttcc aggttatgaa
     1501 gcgcctgttt atgtcgcatg gagtggccgt aatcgttcgc cattagtacg tgtaccagaa
     1561 tctcgcggtt tatccacacg tttggaattg cggtcagttg atccatctgc aaacccatac
     1621 ttggcaatgg cagtattgtt gcaagcagga ctagacggta tccgtaatca gatcacaccg
     1681 ccagcagctg ttgaccgtaa catttatgta atggatgagg aagaaagaga agctgcacat
     1741 atccaggact taccttcaac tatccataat gctatcaaag aattgcgtaa ggataatgta
     1801 atgattgacg cattaggaca acatatcttc tcaaattttg ttgaagcaaa acgtctcgaa
     1861 tgggcggcat tcagacaaac tgtttccgag tgggaaagag aacaatatct agaactttat
     1921 taaaacagga ataccgtgaa ttagaggctg tgaaatcagc gttttgacct gagtattaga
     1981 gaaactaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
     2041 agctgattga acaccgttta gtggagaggt tgtgaaaaag ctgccctgca acaagtaata
     2101 agaatagcca agcaaaaaca gcttttcttg tttttgaatt ggctgaactt attaccgcag
     2161 atgcaagctt ttgaacaccg tttaccaaga ggttttgaaa aagacgttta gtttcgagta
     2221 ttaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
     2281 agaaactggc ttttgaatac cgtttatcca gaggttgtga gcctaccatt taactccgaa
     2341 tcacaagaaa taatttcaaa aacagcttct catgtttgat ggatattgtg acttgtgacc
     2401 gaggagttgg caggagaaca ccgtttattt agaaataagg aggcacgact tttgtcgcat
     2461 ctccttattt tttacttatg tgattcgtta ccttcaatga atccctacaa ggcacttttg
     2521 ttgaaaaaaa ggtcatcttt gaaaaaatta gtggaattgt tttgtttttg atattattta
     2581 atagaaaaga tatgccaaaa atccgagaac tgtggactac gttttttacg taaaggaggt
     2641 aaataagggt gaaagaaaaa gattgtttct acgataagct atataaactg ttgctgcaag
     2701 taggaaaaag tagttctttg ttaggtggga tattatctat cataatgttt gttttatttt
     2761 tttatctatt atttcactta aaatttttca gtaacgattt tctgatttgc ttaggtttaa
     2821 cgttagctat gtttatatca agcttattat gtgggttaaa ttttttttgc actcataaag
     2881 gacttaagaa ataatttctc aaaggatatc gaaaaagaaa aaattgtaag cggatagtat
     2941 tcatttgagt acttgacttt cccttagtca gcttgtatta tacaccttgg gcaccctttt
     3001 agagggtcag aagtttacag aaatttcggc tccctattct tattgaagaa tagggagctt
     3061 tgtttattgt ctgagacttt tcctgcacat aaattaaaaa ggagtttttg aacttatgac
     3121 aaaatatatt tttgtgaccg gcggtgtcgt ttcatcaatc ggaaaaggga ttgttgcagc
     3181 ttctttagga cgcttattga aaaaccgcgg cttaaaagta actatccaaa aatttgatcc
     3241 atacatcaac gtggatccgg ggacgatgag cccatatcag cacggagaag tattcgtaac
     3301 agatgatggt gctgaaacag atttggatct gggccactac gaacgtttta ttgacatcaa
     3361 tttgaacaaa tactccaacg tgacgacagg aaaaatctat tctgaagttt tgcgtaaaga
     3421 acgtaagggc gaatacttgg gagcaactgt tcaagttatt cctcatatta caaatgagat
     3481 caaagaaaaa atcatgcgag cagctaaaat gactgattca gatgtgatca ttacagaagt
     3541 agggggaaca gtaggggata tagaatcttt gccattcctt gaagcacttc gtcaaatgaa
     3601 agcagatgtc ggtacagata atgttatgta tatccataca acattgattc cttacttgaa
     3661 agctgctgga gaaatgaaaa ctaaaccaac gcagcacagt gtaaaagagc tacgtggttt
     3721 aggtatccaa ccgaatattt tggtggtacg tacagagcaa cctgtttctc aaagcgtgaa
     3781 aaacaaattg gcacaatttt gtgatgtcga accagaagca gttatcgagt cgccagatgt
     3841 agatacactt tactccatcc cattagtttt acaagcacaa ggaatggatc aaattgtttg
     3901 cgaccattta aaactagata caccagaagc agacatgaca gaatggaaag aattagaaga
     3961 acgtgtcttg aacttgaaga aaaaagtacg gattgcgctt gtcggtaaat atgtcgagtt
     4021 accagatgca tatatctcag tagttgaagc attgaaacat tctggtttcg cctataattc
     4081 agacatcgag atcgattgga tcaaagcaca agaattaacg agagaaaatg tagaagaacg
     4141 tttgaaagac gcagatggaa tcttggttcc tggtggattt ggtgatcgcg gagtagaagg
     4201 gaaaatcgaa gcgattcgtt atgctcgcga aaatgacgtt ccgtttttag gtatttgtct
     4261 tggtatgcag atggcttgtg tcgaatttgc acgtaacgtc gttggattag aagatgcgtc
     4321 atcagctgaa acgaatccag atacagcaaa caatattatt gatttaatgg ctgatcagga
     4381 aaacatcgag aatttgggtg gaactttacg ccttggatta tacccatgta aaatcaaaaa
     4441 aggaacgaag acggctgaag catatgatgg agccgatgtt gtgcaagaac gtcaccgtca
     4501 ccgctatgag ttcaataaca aatatcgtca attgtttgaa gaacaagggc tagtcttttc
     4561 aggtgtctca ccagataacc gtttagtaga aatcgtagag ctgccagaga aaaaattctt
     4621 tgtgggatgc caattccacc cagaattgat ttctcgtcca aatcgcccgc aaaaattaat
     4681 caaagcattt gtcggagcat cattagcaga tcacgaaaca aaataatttt tgaacttgat
     4741 agaaagagaa aagtagcaag agaaggggat aagcaatttt cttgtcactt ttctcttttt
     4801 ctgatttgtt attatttgta ggaaaaaaga tagaaagcaa aagacttttt tcgattaaag
     4861 cgctattgga tattttattt tttgcaaaaa acttcttgaa aattttcatt ttcattgatt
     4921 ttagtagaaa actaccgaaa tgtttggtaa aatagggtcg ttggttaaga attgtcttaa
     4981 caaatttagt tttacaaaac ttaggaggaa ttttattatg ccagtagtat caggagctga
     5041 atttttaaaa gctgctcgta aaggcggtta cgctgtcggc ggattcaaca caaacaactt
     5101 ggaatggact caagcaatcc ttgaagcggc tgaagcaaaa caagcaccag tacttatcca
     5161 aacatcaatg ggtgcagcta aatacatggg tggttacaaa atctgtaaag atttaatcac
     5221 tgatttagtt gaagcaatga acatcactgt tccagttgct atccacttag accatggtga
     5281 ttacgaagct gctttggaat gtatcgaatt aggctatact tcagtaatgt tcgatggttc
     5341 acatctacca tttgaagaaa acttgaaatt agctaaagac gttgttgaaa aagcacatgc
     5401 aaaaggtatc tcagttgaat gtgaagttgg ttcaatcggc ggagaagaag acggaatcat
     5461 cggtaacggc gaattagctg atattgaaga atgcaaacaa atggttgcta caggtatcga
     5521 ctacttagct tgcggtatcg gtaacatcca tggtcaatat ccagaaaact ggaaaggatt
     5581 agcttttgac cacttacaag caattgctga tgctgtaggt ccagacatgc ctttagtatt
     5641 acatggcgga tcaggtattc ctcaagatca aatcgaaaaa gctatctcaa tgggtatctc
     5701 aaaagtaaat gttaacactg aattccaatt atcatttgct gcagctactc gtaaatatat
     5761 cgaagctggt aaagataaag aaggtaaagg attcgaccct cgtaaattat tagctccagg
     5821 taaagcagca atcgttgaag atgctaaatc tcatatcgac tggttcggtt cagctaacaa
     5881 agcgtaagca tccacataac agatacgata tataggaatg gagaacgact tttgaagtcg
     5941 ctctccattc ttttttactt aaaacggcag accatgctcg tttctttttt ttatctatga
     6001 taaaatacaa gcatatccat gaaaaaagat taataaacaa ggtggaaaca gatgaaaaaa
     6061 atcgtaatca aaggaaaccg acctttagct ggtgaagtaa cgatcagcgg tgcaaaaaat
     6121 agtgcagtcg cattgattcc agctgcaatc ttagctgatt ccccagtgat cttggaaggt
     6181 gtgccggaca tacaagatgt tcattcatta attgaaattt tagagatcat gggcgcaact
     6241 gtccattttt ccaacaacat actagaaatc gatcctcgag aagtcgtatc gattccgatg
     6301 ccgcacggaa aaatcaatag tttgcgtgct tcttattatt ttatgggaac actgcttggt
     6361 aaatttggcg aagcggtagt aggcctgcca ggtggctgtt atttaggccc tagaccgatt
     6421 gacctacacg tcaaaggatt tgaagctcta ggtgctgaag tgacaaatga acatggtgcc
     6481 atgtatttac ggacagaaaa taaaggattg cgtggcaatc ggattttcat ggacgtggtt
     6541 tcagtcggag caacgatcaa tgtgatgtta gctgctgtaa aagcaaaagg acagacagta
     6601 attgaaaacg ctgcacgaga accggaaatc atagatgtgg caactttact gaataatatg
     6661 ggggcaaaag ttcgaggagc gggtacagat gtgatccgta tcgaaggagt cgaaacatta
     6721 catggctgtc ggcatttcat gattcctgac cgcatcgaag caggaaccta tctagcatta
     6781 gcagctgcag taggaaatgg tatcaaagtg aaaaatgtga tctttgaaca tttggaaagc
     6841 tttatagcaa aattgcagga aattggtgtc catatgaaaa tcagcgaaga tgaaatcgaa
     6901 gtttacccct cgaaagaatt aaaacccgca aacatcatga cctatcctta tccaggattt
     6961 gccacagatc tgcagcagcc acttactgcg ttactattga tgactacagg cacttcagaa
     7021 atcatcgata cgatctatgc gaaacgtgtg aaccatgtgc cggaactagc acgaatgggc
     7081 gctgatatta ccgtggaagg aaatatgatc atcgtgaatg gtccaaataa acttcacggc
     7141 acagaagtcg tggcttctga tcttcgggca ggtgcttgtt tagtgattgc tggactattg
     7201 gcagaaggga caacgacgat ttacaatgta gattatatct tacgcggtta tgatcatatt
     7261 atcgagaaac taacagcctt aggggcatca attgaaatga tagaggaagt gggagctgaa
     7321 tgagcgatta tttgacaatg gcagaactag agaacaaaac gttaaaagaa gtttatagtt
     7381 atgccaaaga atttaaaatt ccttattaca gtaagatgaa taaaaaggaa ttatctctag
     7441 ctgtgattcg tgcacaagca gagaaacaag gattttatta tatggaagga atattggata
     7501 tcgttggtca agatggttac ggttttttac ggccaatcaa ttatggacca agtgcagaag
     7561 atatctatat ttctgcctca caaatcagac gattcagttt gagaaatggg gacaaagtgg
     7621 caggaaaagc ccgtccacct aaagaatcgg aacgttatta tggtttgatg cacgtggaaa
     7681 gcgttaatgg aaaagatccg gaagaagcaa aagaacgtcc gcattttcca gccttaacac
     7741 ctctttatcc gcaaagacag cttcaactgg aaacaacacc gcaaagacta tctacccgaa
     7801 tgatcgatat cttttctcca atcggttttg gtcagcgtgg attgatcgtc gcaccgccaa
     7861 aagcagggaa aacttctgta ttaaaagaaa tcgcaaatgg tatcaccgaa aactatccgg
     7921 aagtagaatt aatcgttcta ctgattgatg aacgaccgga agaagtaacg gatctagaac
     7981 gaagcgtgaa aggcgacgtg gtatcttcta catttgatct gcagccgcaa aaccatactc
     8041 gagtttctga attagtattg gaacgcgcaa tgcgtttagt cgaagataaa cgagatgtcg
     8101 ttatcttgat ggatagtatt actagacttg ctcgggccta taacttagtc gttccaccaa
     8161 gcggacgtac attgagtggc gggattgacc cagccgcatt gtataaacct aagaaatttt
     8221 tcggggcagc aagaaacatc gaagaaggtg gcagtttgac gattttagcg accgctttag
     8281 tcgatacagg aagccgtatg gatgacgtga tctatgaaga attcaaagga actggaaatc
     8341 tagaattaca actttcacgt gaattatctg aacgtcggat cttcccagcc atcgatatca
     8401 aaaaatcagg tacccgaaaa gaagaattat tgatgccaag tgaagaatta gaagaaattt
     8461 ggaaacttcg aaaaaatatg actggagatt cattagaata tacggaacaa ctgatccgct
     8521 ttttgcgtaa aacaaaaaac aatcagcaat ttttcaaaga atttcaagat gtctcctttg
     8581 gtaaaaaaaa tccgaccaga aatctgaaaa gataattgca accttgactg aaacatgtta
     8641 agatgttaat gttgtaaatc gacaaatcaa ctctggttca gcaaatggag cagggcaaag
     8701 gagcgaaaaa atcatgaaag aaaacatcca tccagattac cacccagtag tattcatgga
     8761 ttcaacaact ggtttcaaat tcttgtcagg ttcaacaaaa acttcacaag aaacagttga
     8821 atgggaagac ggtaatacat acccagtcat ccgtgtcgaa gtaacttctg actcacatcc
     8881 attctacact ggacgtcaaa aattcacaca agcagacgga cgtgtggacc gtttcaacaa
     8941 aaaatacggt ctcaaagacg caaacgctgc ggaataataa aaacgctgat aactcaacgt
     9001 ttagcagact atctgatagg gatagtctgt ttttttatgt tttttgccaa tttaaaactt
     9061 cgtttgatgc tgaaaaagtc gtaggatcat aatgcacaaa acaatgaaaa actagtatat
     9121 agttttaatt atccacttga taaaaacacc ttatattaac gaaatgaaga ggggttattt
     9181 cgaagtaaaa aaccatttac ctaaaattag aagctaagct ttcctttcaa ggaaggcttt
     9241 ttgttttgtt atagacttgc gattgtttgt gagctagatc gttcatttta atgacttata
     9301 cacgcggatg atgggtcttt ttcctctgtt cattcataat attgaacggt acagctagcg
     9361 atgctatact gacctcagtt ccaagaaaac gttaacattt tttgtggggg agaggttttt
     9421 tatgaggttt gatcaattga tcgcagaaga actgattgtt ttcgatccat cgatagattc
     9481 aaaaggatca ttatttgagc gaatagggga tgtgttgaaa aaaacaaata aggtaagaaa
     9541 tgttcaaaaa gtcgttaagg cactattcaa acgagaggag gagatctcca caggaataga
     9601 agatggattt gggattcccc atgcaaaaag caaatatgtg acaaaaccag cactgtgttt
     9661 ttttcataca gccaaattaa cggactatag cgggatagat gaaatgccaa ttgaatatat
     9721 ttttgccatc gtagttcctg aaaaatcagc agatatgcat ctagagattc tcagcacact
     9781 ctccagacga ttgatgaatg cagattttag aaagggaata aaagaagcca ctacgccagc
     9841 agatatcatc agacagatta gtcaagaatg aaaatagtag agtctttgtc cgagtatcga
     9901 tagtgaagaa aaaggaggaa aataatcatg aaaatcgttg gtgtaactgc ttgcccgact
     9961 ggaattgctc atacttatat gtcggcagaa aaattagaag taacagcaag aaatctaaac
    10021 catcaagcaa aattcgaaac acaaggtgta aaaacagaaa atcagttatc tgaacaagaa
    10081 atcaaagagg cagatgcaat cattcttgca gtagataaag aaatcgaatt ggaccgattt
    10141 gccgggaaaa aagtaaagcg tgtctctaca agccgagcaa tcaaagaacc gcaagtagta
    10201 atagacgaag cattgagaga tattggcgta ttcgttgtgt ctaatgaaaa agaaccagct
    10261 gcaaatgaga aaaagccgac aatctataat catttcatga atggtgtgaa ttacatgctt
    10321 ccatttgtga tcgcaggcgg aatcatcatc gcactgagtt ttgcctttgg gattacagcg
    10381 gctgatccca actcagcaga ctataatgtg ttagcagctg cattttcaag gatcggagga
    10441 gatacagcgt ttgccatgat ggttcctgcg ttaggcgcgg ggattgctac atcgattgct
    10501 ggaaaagcag gttttgcccc aggaattgtt gccggattac tggcctctac aggtggttca
    10561 ggttttcttg gcggaatgat tggtggcgtg ctagcagggt atatctgtga ttttctggca
    10621 aataaaatta gcgtaaaaaa agaattttct gctatttatc agctgattgt cgtccccttt
    10681 ttatcgatct taattattgg gcttttgatg gtatttgtga ttgaacaacc gatcacatgg
    10741 gtgttggatg ctttgacaaa ttggctgaat agcttgggaa atacatccgg gctattgttc
    10801 ggattactta tcgggatcat gatggcagct gatatgggtg ggccgatcaa taaatcgact
    10861 tcgactttct cgatcggttt gatgtcagct ggagtaaatg caccgattgc tgcttgtatg
    10921 gctgcaggaa tgacacctcc cctaggtatt gctttagcca ctttattatt caaacataaa
    10981 tttaccaaag aagaacggac ttcaggtcaa tcatgctgga ttttaggcgc ttcgtatatt
    11041 acagaaggtg ctataccgtt tgcggtatct gacccgatcc gcgtgatacc tagtttgatg
    11101 acaggttcag cagtcgctgc agggatttcc atggcagtag gagttacttc aatggcacct
    11161 catggaggga tttgggtgat gctaattcca aatgttatga acaatttacc tatgtatgtc
    11221 ttggcaattg catcaggtac agtcactaca gcctttatgc ttggactatt gaaaaaaaca
    11281 gtgaaagaga aaaaacaaga caagtggacg aaaaatgaaa atctaacaaa tgaggtggaa
    11341 gcgtaatgtt atatacaatg aaagagttat tgaaagtggc taaagagaat caatttgcag
    11401 taccagcctt caatatttgc agctatgata tgatgaaagc aatcatcgaa gaagcagaga
    11461 gattagaagc accagtaatc ttagaaattc atcctgatga aatcgcctat ttaagtgatg
    11521 agtttgttgc ggcagtaaga gcctatgctt atacaagtaa actgccgatc gttatccact
    11581 tggatcatgg cggtacgata gaagatgtct tacgggcgat tcgaaacggc tattcttccg
    11641 tgatgatcga tgcgtctttg aaatcattcg acgacaatgt acagattacg aaaaaagtgg
    11701 ttgcgttagc tcatgcggta aatgtctcag tggaggctga gcttggaacg attgggaata
    11761 atggttctgc tgaaggaggt gctgaaacaa tcatttatac agatcctgat caagcgaaga
    11821 tttttgtgaa agaaacagga atcgatacac ttgctgtagc aattggaaca gcgcatggct
    11881 tgtatccgaa aaacagaact ccaaaattaa atatcgactt actgaaagaa ttgaaccaac
    11941 aaatcgatct tccatttgtt ttacatggcg gttcaggtaa tccggacgca gaagtcagcg
    12001 aagcagtaaa atacggagtt gccaaagtga atttgagctc agatcttaaa agcgtctttt
    12061 tcaatgcttt gagagaaata ttgagtgaaa atccatcgat gtacgagccg aatgcaattt
    12121 atccagcagc taataaaaag gtacaagaag tggtcaaaca taaaatggaa attttgaaca
    12181 cagtaggcaa ggctagttta tactaaaaat aaaaatgtgt ggtcaagagg gtatgacaat
    12241 agtcttgtca taccctctta accacacacg atgttcagaa gtagtttttt cgaaaaattt
    12301 cttcttattt ctcgaagcca atcacttctg tcacaacctc ttttttcctg ttactatata
    12361 aagtaaatgg ggtgatttta tgttgaatga agtggagaat agacagcagg agattgtgaa
    12421 ttatctaaaa aacaaccaat ttgcaagagt caccgatttg atcgagttag taaattatag
    12481 cgaagccacg attaaacgtg accttgtttt tctggaaaaa agtggattga tccgtagagt
    12541 tcgcggtggc gccatgctta ttgacaatcg aaaaattgac gtgccttacc tgatgaagat
    12601 caccaaatta gaagaagaaa cagaaaaacg taagattgca gatacagctt cttctttgat
    12661 tcgagatgat atggtcttat tcttggattc cagtacaacc tctttacact tagtcagaaa
    12721 cctagcaaga tttgatggtt tgcagatcat tacgaatggc atcgtcacag ctgctatgtt
    12781 gagtgaatat acaacggcaa aagtatctgt attgggaggg gcaattgttc cgaaacgagc
    12841 aacaatcaac ggttcaaaag cctataacga tgcattgtca tattatgcgg atttagcgat
    12901 aatgagttgt cgcgggctag atttcagcca aggagtaaca gaaactcatg aaggagaggc
    12961 aatggtcaaa aaagctttta gaaaacaatc agaccggctt gccgttttag ttacacagca
    13021 aaaaattgca cataaattca tgcatcaagc cattgctttt catgaaatcg attatctggt
    13081 gacaagtaaa gaactgacaa aagaacagta tgcgaaagta aaggaacacc atatcgaatg
    13141 tctgtacgga taaattatta cgtgaatgtt ctaagtggct tcctcatttt tagataggac
    13201 cttatctttg ctcgcttctc tcagccgatg gtataataat gaaaaggtta tcttgttaga
    13261 taatcttact tttttatcca ggagaaagga gtgcagaaaa tgaaacatgt gaaggcgttg
    13321 gtagtgaagg caatcatgat ctgggcgatt ctgtgggtcg tgctgacagg tttatacggt
    13381 gttagcttta tggattcaac gattgttggg gtaattattg tagtcatgat ctatgtgcta
    13441 ggggatctgt tgatcttacg taaagtaggg aacatcgcag cgacgatcgc agatgctggt
    13501 tcagctgcag ttatcttgtg gctctatcta tattttatga atgatacagt cgatatttgg
    13561 atgaaagtat tgattcctgc tctattgatc ggtgtggcag aatggttctt ccacaagtgg
    13621 ttgctaagtc aaggcatcgt accagatgaa cggaaaatgg aataaatcaa cagttaaact
    13681 attcttatcg ataaatgaaa gctttaaaaa taaatagatg tttaattaag aataatcata
    13741 aactattttt actcaaaaaa ccgctcagat tattttcaga tctgaacggt tttttttatc
    13801 tattcatcaa gatcaaattt catttttcaa tgattcaatc aattcgccct ctgcttcatg
    13861 actatgtttt cggccattaa caagatagag tgctgtacat atcaatggaa tgactccggc
    13921 aatcacatac aatcctctaa atgaagtaag agattttagc atccccatca aataaggacc
    13981 aacgcctaag cctaggtcta aaccaataaa gtaggtagat aaagcaatac tgattcgatg
    14041 ttcgcggacg atttttaaac aaacagcctg tccatttgac ataaacgtac cataacctag
    14101 gccgactaat gctccagaga taagcaatgt cacactattc gtcgttacac tcagtaaaaa
    14161 taatcctgct gttaagaata aatagctagg atacatcacg tattgttctc ctttgacatc
    14221 gaaaatcctt ccagtcaatg gacgtgtaaa tgtgatgacc aaagcatata cgacgaagaa
    14281 aaatgaccca gcagcaacta agtggattac ttttgtataa gaagataaaa atgataaaac
    14341 acttgaataa gaaagaccca tcaaaaaggc aattcctgta atgaaaagtg ctttcttttc
    14401 aataaaacta ttgatattcc atgagcgaag agatattttt tgttcttcag ataatggaat
    14461 attttttaca ggaaagacaa ggcaggcaat cgtaacaaag aagaccagta caattgaaaa
    14521 ccagataatg aaacgaaaat cagtcatatt cagcaaaatc attcctaaaa atggcccaac
    14581 agcggcagct aaactagtac ttaatccata ataattgatg ccttcccctt ttttagatgc
    14641 agggatatat gcagtaacga tagcatttgt agctgtagaa actgtaccgt agccgaatcc
    14701 attcaagaat cgaactaaat acaatgcccc gatagttggc gtataaagat atgctaatgt
    14761 tgaaaggaga tagaagatcg cgccgcctct taaggtaaac ttccgaccaa atagttctaa
    14821 ctgtttcccc atgaataagc gtgccagcaa tgttccgatg atatagatcc cagaagcaaa
    14881 acctgcttgg ctcaagctgg cgtgtaaggt gtcttgcgca atgactgcca tgatgaccat
    14941 caacagataa taaatcaggt agacaataaa attgatcaat gtgattccaa taaaatattt
    15001 attaaataat ttcttttcca tgtatgttat acattcccct taagctgaat atgcttttaa
    15061 tttttgtatt tgaacttcta catcgtgata attggatgga tagcgatcaa caagttggcg
    15121 aataaataaa tctcttgtag acataaacag atttaaaaat tcttcgcatt cgtttgttgg
    15181 attctcatcc actgctttga tcaattcgat cgagttttga tacgcatcat ttaaaaagac
    15241 taaagaagct ttcatatcaa atcttgtttg atatgctgtt tctaatcgat taatgattgt
    15301 gttcatccag taattcatgt tttttccctc tattcttaaa aaattttact tctgcagtat
    15361 aacgaataaa aaaaaggaaa aaaatcgcat aagtgatgga aaaaggtact taacaaatgt
    15421 taatatcatt agtaaaatac ctttggactt taaaaagttt taaagtactg tatgatcttt
    15481 ttagatgaaa gtttggatgg gggagcatca ttggatagta gagtcttaaa ggaatatttg
    15541 gataaaaatg attttccgat tatacgcaaa ggatatcata aatatttgac attcgaaggg
    15601 atggaagatt cccatacgta tatcttgaaa gagggaacgg taaaagcaag tgttatttca
    15661 aatgatggga gagaatttaa ccttcgctat atcaaagatc ttgaaatcgt ctctctttta
    15721 aaagacgaat attcacaatt catcgattcg ccgtataata ttcgagttga atcagaatat
    15781 gcagagtttt atcgaatcaa tcgtgtgcgc ttttggcaaa atatcaacca agacccaaag
    15841 ctacaacact atgtaaaaga gtattaccgc tatcgtctgc tttattcgat gaaaaaaatg
    15901 cagcaaatgc tattaaacgg aaagctggga gctgtttgta cgcaacttta cgaattatat
    15961 gatttattcg gtgtgcggac agaagaaggg atgctgatcg atttttcgat cacgaatgaa
    16021 gaaatcgcca aattttgtgg catctcaact gctagcagtg taaacagaat tttaaaacaa
    16081 ctgaaaaaag atggtattat caccgttaaa gaccatcata tcgttatttt gaatatggac
    16141 ttgttagaag acaatattat cttttgatga acaaagaggt tgtgaaatca gcgttttgac
    16201 ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt ttttgagcta
    16261 ataccgaggg tcagctgatt gaacaccgtt taccaagagg ttgtgagcct gccgtttaac
    16321 tctgagtcac aaggaacaat ttcaaaaaac agcttttcat gtttgatgaa tattgtgact
    16381 tgtgaccgag gagttggtag gagaacaccg tttaccaaga ggttgtgaaa aagctgttct
    16441 gcatcaagta ataagaagag ccaagtaaaa acagtctctt atgtttttaa cttggctgga
    16501 cttatcaccg tagatgtaag cttttgaacg ccgtttattt gcaacaaaag gggctgtgac
    16561 acgatttttg tcacagccct ttttttgcga acattcattt agcaattttt agaaacttct
    16621 gccgccaccg ccaaaagtcc cgccaccgct agaatgggta gtacttccgc caccgccgct
    16681 tccaggaggt gggcttttgg ggattcttct tgtcgtgaca aaagaatttg tcagacgatc
    16741 ggttttttca gttaatttga tactggattt ttctcggaat ggatatttgt agatgcctga
    16801 tttcaattga taacgcgaaa cagtcacaaa ataaaagaca agactaagga taagagccaa
    16861 aacaacagca atgatgattt ctactgtcgt caaaacctta tagcgtgtaa ttttgccagt
    16921 ttcttcgtct acacgataat gtcctcctgg aactccgtct tccacatatg ttgctgattt
    16981 agacaggtaa gcttttgcag cattgtaata ggcagcattt gtcatctgat cataaacatc
    17041 atctaagatc gaatcgattc tgctatcagt caaataatcg atcatattac cagaagtcga
    17101 aatgtagatt tcacgctgtc ccatatctaa tagcaatact gagccatttt gatcatttcc
    17161 gactgcgtct cttaagtaat tatcagcaaa gtctcttggt tcttctgaat tagatgtagt
    17221 cgttacgatc aagactcgtc ctttgatttt ttcattcagc ttttctgcct gttgttccaa
    17281 agattggatt tgatctgttg tgaataaccc agcctcatca tttaccgtag ctgtatctgc
    17341 atgagtagcc accggccagc caacacttac tagcaaaaga aagaataaaa aaaatttttt
    17401 catcatatca agtaacctcc gatcagaaag aggatcgcta gcccagcgaa aatcccaaga
    17461 gcggtcagtc ccaatttttt ctggctgatc ggcaggacac cgctgacctt tcctgtttgt
    17521 ccattcattg cgtagtagta gactttttta cttgagtcat tgcttcgata agtaacaagc
    17581 cataccggca gtaatacgta attatttact tcgtttgtga ttgaagcaga agttcgcaca
    17641 ccggtcaatg ttgtatatcc atttgcggta tcttttaaca gcttctctga atagtctttt
    17701 aattcagatt gaatctgtga tttgattgcc tcatattcga tatctctttt ttctgcttgg
    17761 aacccggcta aatactggct tttaaaatca attgctttat ctaacgggaa aggttgcacg
    17821 ccttcgacca tcttttgttg cgtatttttt gataaggcat tttttactag ttctttaaaa
    17881 gaaagcttgc ctgctcttga aacagcaaat tgcttcgttt ctgtgtattc gatgtcacct
    17941 atccgccata tgcggataac tgtaccattc gcctgcatgg caccatctac ttcagcatct
    18001 gtagcccaat aagggaaata cacacctgtc aacttatcga tttgatcctt attgaaaaaa
    18061 gctttgggaa caaaccattt tttcttggtc caagcgagaa atctgttgat tgcttcttct
    18121 ttctcgacag caaaaggaag tactttattt ggcaagaatt ctccgcttaa acgtcccgat
    18181 agtacgacgg gattatggca gtagtaacaa taagtcgcag cagttgtcgc atcagtcacg
    18241 atctctgcac cacagttggg acaaagaaaa agatctatcg ctgcggtatt atctgcagat
    18301 tcgtccgctg tatctgaaaa accgcctgcc tcgtcaaccg ctttgcgctc ggcttcattc
    18361 atatcggcaa gctgttcttg ggctgtaaaa gtaaaatctt cggtaggtga aggttcttct
    18421 ttgctttctt cgccagccat acgcgcttct ttttgctttt gctcatattg gctgacttct
    18481 tcttctgtat agatattcag gcagtattcg caatgaaatt tttggtcttt gggatcaaaa
    18541 gtcaacggac cgccgcaatt aggacattta tgtgtaagaa catccatcag ctgcacacct
    18601 ttctaaataa attaattaac ggggattcct ttaaacggtt taccacagtt tggacagaat
    18661 ttagggatgc cgttggaaag atccacgatc tcattgcatt cactgcatcg catttgtagc
    18721 ttaggctgaa cgttttctac aggtttggca gctccgcagt tggaacagaa ttttccggaa
    18781 ttttctgtcc cgcaaactgg acatgtccaa gtatccgcat ttccttgtgc agtttgttga
    18841 ttttgttttt ctgcttgttg tttgatttgt tcttggttat tttgagctgc ttgagaaaga
    18901 taagaaccat ttgcattcat tcccatacct acacccataa agccggtcat tgctcctgct
    18961 tcattttttc cggctgcttc cataccacgt gcaatggaac cttgcacgta tccttcacgt
    19021 acgctaggat cacctagcat cgccccttcg ttacgcatat tgatcagttt cacagaatca
    19081 tcggtgtaag aaatgctggc tacagccaca gaaacaatct ccatcccacg taattcacgc
    19141 caagaatcat ccaatgcagt atccatgtat ttgcttaatt ccaaactctt agatggtaca
    19201 taagaaatcc gttgaccatc tgcagacatc tgattgattg ctgattgtag cgctgttagg
    19261 aattcagcta aatactgctc attgatatca ttgatttcca cttgtgtttt gtttttaggg
    19321 attgcgtttg tataaaataa aatcgggtca acgacatgaa tagaataagt gccatgtgcc
    19381 cgtaagaata attctgcgtt atagaaattg tcaaagtagt tcaacggcgc gcttgtaccg
    19441 aatttgattc cctttatttc ttggagattg atataaaaaa cttgttgttt ctgcggtgtg
    19501 acgccgccaa atttgaatcg gtcaaaagtt tcagcaattg cttctttcag tgttccattg
    19561 aacatggaag gagctgcgtc atttttaatg gtgtaataac cttcctcagc ggtataatcg
    19621 atgatttttc caccatcgac caaaagcatc atcatgtttg gatagacatg gacgactgtt
    19681 ccgtctgtta aaacatcttc tgttccttta cgattggagc cacgtttgtc atctttgcgg
    19741 actttgacac ctttcgtcat gaccgttgta tcactcatat tgtctggttc gatgacttct
    19801 agccattgat ctgccagacc gccgccaacc atacttgttg ctgctttgat aagacccata
    19861 aaaaattcct cctctgattc agctagtgcc aaacaattat tgtttattta ttataccata
    19921 ggaagatgtg aaacttctcg gactagagac ggaattgaaa tggaaaattg cgtattgttt
    19981 aaatacctga aaaagccgag aaggatagta gtttttttac ctaatatcac gtataataag
    20041 agatagtgaa ttttttaaaa aagggggatc cttatggcat atcaagcact ttatcgagtc
    20101 tggcgttcgc agcgtttcga agacatcgtt ggacaaaaag ctgtgacaca gacactaaaa
    20161 aatgctattg tttcccacaa aacctcacat gcctacttgt ttacaggacc cagaggaacc
    20221 ggaaagacga gtgcagcaaa gattttcgca aaagcaatca actgtccgaa cagtaaagac
    20281 ggtgagccat gcaacgaatg cgaaatgtgt cgatcaatta ctgctggtac gcaagaagat
    20341 gtgatcgaaa tcgatgctgc cagcaataac ggagtcgaag aaatccgatt tatccgtgat
    20401 cgggcaaatt atgcgcctac aaaggcagcg tacaaagtgt acattattga tgaggtacat
    20461 atgctttcaa caggagcttt caatgccttg ttgaaaacat tggaagagcc aaaagaaagt
    20521 gtcatattca tcttagcaac gaccgaacct cacaaaatac cagctacgat catttcacgg
    20581 actcagcgat ttgattttaa acggatcaat acggcagata ttgtcgaaca tcttgaattt
    20641 atcttgaaag aatcgactat cagctatgaa ccagctgcat tgaatgtgat tgcccgttct
    20701 gcagaaggcg ggatgcggga tgcattgagt attcttgatc aggcaatctc gtttagtgaa
    20761 ggaacaatta ctttagatga tgccatgcaa gtgacaggta gcttaactga cgaaatgatg
    20821 gacagttact tgagtgcttg cgtgaaaaaa gaagtaccag aagcattgga aacattgaac
    20881 caaattctcg cagccggcaa agaatcacgt cgctttctag aggatatgtt acaatactgc
    20941 cgtgacttgc tgatgtatca gcaagcacct aacctagttg aggaacaatc gagtacgatc
    21001 agaagtacat ttacagaatt ggcacaaact gtttcagcgg atcagctgtt ttcaatgata
    21061 aagattttga gcgatactca aaatgaaatt cgttttacca atagtgccgc tatttatttg
    21121 gaagtcgcta cagtcaaact tgcacagcta ccgtctgctt ctgttccttc agcagatgta
    21181 gcatttgcag atgatcagat agtaaaacag ctacaacaag agattaagga actaagaaac
    21241 gaaatcaagg aactacgcag taatacagga attgagaata caaaagtaca gccggtacag
    21301 caaacaaatc ataaaaaaca gacaagtacc tatcgtgtac cgacggaacg agtatataaa
    21361 gttctgcggg aagcgacaag acagcatctg aaccaagtaa aagaagtatg ggaagacttg
    21421 ctgatgagtc tatctgtcac tcagcgagca atgcttaaag caagcgaacc agttgcagct
    21481 ggacctacag gactagtgat tgcgtttgat tatgagattg tttgtcaaag agcagcaaat
    21541 gacgaagaat tgcagctttc ggtacacaac aacttaagcc gaatgatcaa agattatgcg
    21601 cctgatcctg tttatattac aagagaaagc tggccagaac ttcgaagaaa ttatttgacg
    21661 caggcacaag aagagggaac agaaaactct tttgcttctg aagactcaga aggagaaatc
    21721 gagttgcttc ctcaagaaca agaagtacca gaagaaacac ttgtagtaaa agcagaggaa
    21781 ctgtttggct ccgaagctgt tacagtggta gatgattaat aaaaaggagt agataattat
    21841 gatgcgtgga atgggcaata tgcaaggcat gatgaaacaa gtacaaaaaa tgcaaaaaga
    21901 aatggcagaa gcacaagagc tgctaaataa aacagagttt acaggtaaag ccaccaatga
    21961 attggtcaaa gcggttttta caggcgatcg tcgcatgaaa gatatccaaa tcaatgaaga
    22021 agtcgttgat cctgatgata tcgagatgct tcaggatctt gtcgtaatgg cagtcaatga
    22081 tgcgatcgca caaattgatg tggaaactga gaaaaaatta gggaaatacg caaaaggttt
    22141 gccaggattt tagttttaaa ctgaaggagt aatgaatatg caatatccag aaccaattgc
    22201 gaaactgatc gacagctaca tgaaacttcc aggaatcggt cagaaaacag cgacaagact
    22261 cgccttttat acgatcgata tgaaagatga agtagtaaat gaatttgcta aatctttgtt
    22321 aagtgtaaaa cgcgatttgc atttttgtag tatctgcgga aacatcacag aagaagatcc
    22381 ctgcgaaata tgtagaaatc cttcacgtga tcgaagcgtt atcctagtgg tcgaagagcc
    22441 gaaagatgta atggcaatgg aaaaaatgcg agaatatcac ggactttatc atgttctcca
    22501 tggtgtgtta tcaccgatgg aagggacagg tccagaagac atcaatattt cttctctgtt
    22561 gcagcggctg catgatgcag atgtaaaaga agtgattatc gcaacaaatg caacaacaga
    22621 gggagaagca acagctatgt atctctcacg tctgatcaaa cccgcaggta tcaaagtgac
    22681 tcgtctagca catggtctgt ctgtaggctc tgatatcgag tatgcagatg aagttacttt
    22741 attgaaagct gtcgaaggaa gacgtgagtt ataaatttct aattaagtgt tttttcagat
    22801 acaatataaa agcagcacaa gagatggggg caacaatgtg aacggactat ttattacaat
    22861 cgaggggcct gatggtgcag gaaaaaccag catcttgaat gaactttacc ctcttttgaa
    22921 agaagtagca aaaacagaaa tcattcaaac aagagaacca ggaggcattc cgattgctga
    22981 agagatccga gcagtgatcc ttgatccaaa aaatgatcgg atggatgaac gtacggaagc
    23041 actgctttat gcagcagcaa gaagacaaca tctagtcgaa aaggttctgc ctgctctggc
    23101 aaaagggaaa atcgttttat gcgatagatt tgtcgacagt tctcttgctt atcaaggtgc
    23161 aggccgacgc atcggcgtta ccgagattgc tcggttgaat gagtttgcta cagaaggtac
    23221 tacgccggat tttacccttt atcttgacgt agattcagac accggattaa gaagaatcaa
    23281 gaaaaacaga caaaatcaaa tcgaccgttt agattcggaa ggtttggaat tccaccagcg
    23341 tgtacgtcat gcttacttaa agctggcaga agagaatccg gaaagaatcc acaaagttga
    23401 tgcaagaaaa agctttgaag aagtgctgca aacaagttat catacaatta ttgaacagta
    23461 tccgcaattt tttgaaaact aggaaggtga acgtttatga aaattatttt agcgattatc
    23521 caagacaaag acagcaaccg tttatcaaat gaattgattg atgcaaatat ccgtgccaca
    23581 aaactatcat cgacaggcgg cttccttaag gctggaaaca gtacgtttat cgtgggtatt
    23641 gaagatgacc gtgtagaaga agcattggaa atcatcaaaa aaacgtgtga atcaagaaag
    23701 caatttgtat ctacacctgt tacactggat atttcgatgg atgggggcgt cccttatcca
    23761 gtagaagtag aagtaggcgg tgccacagtc ttcgtcttac ctgttgaagg attccatcaa
    23821 ttttaggagg agctgagcta tgaatcaaga aataaacttg gctcaaatgc aaccgatcgt
    23881 gtatcagcag cttcaacgga gttttgagca tgggcgtatc gctcatgctt atctttttga
    23941 aggggagaaa ggaacaggaa aacatgaagt aggtatatgg cttgcacagc acctgttctg
    24001 tacccaaatg aaagacaatc tgccttgtgg aaaatgcaac aattgtcagc ggatcgaaaa
    24061 gaaagaacat ccagatgttt tggttattga accggaagga caaaccatca aagtcgatca
    24121 gatcagacgt ttgcagacgg aattcagtcg cagcggttac gaatcaagaa aaaaagtttt
    24181 tttgatcaaa gaagctgaaa aaatgaatag cagtgcggca aacagtttgt tgaaattctt
    24241 ggaagagccc cctggagatt ttttagcggt gttagaaaca gatgcagtag gaagaattct
    24301 ccctactatt caatctcgtt gtcaagttct gcattttcaa gaactttcga aagaagcact
    24361 gatccatcga ttgcaagaag agcagattcc attggaaaaa gcaaaacttt tggctttctt
    24421 aacaaacagt ttaggaaaag cagttgaaat ctctcaagat gaatggttta atgatgctaa
    24481 ggacttgatt tatcaatggt tcgtttactt gcaaaagcaa gatactcaag cctttatcta
    24541 tgtccaaaaa aaattggtaa aatcatttaa agaaaaaaca caacagttta caggattatc
    24601 tgtcttgatg ttttattatc aggaagcaca gcgtcaagca gtagcaaacg gcgaatatgg
    24661 caaagtgaaa cagataaacc agataattga acggatattg atcgcagagc agaaactacg
    24721 cagcaatgtc agttttcagg ctgttgcgga acagttcgtt ttgcatacga ttttttagct
    24781 tgccgcaaag gatgatgatc aaggaggatg gaaatggtag aagtagtagg tgtccgatat
    24841 agagatgcag gtcatatcta ttattttgca ccaggagact ctgaatatgt ttatagtgac
    24901 aaggtattag tcgaatctca gcaatcctta catattgcta ctgttgtcct tcctaaaaaa
    24961 gagattgatc ccaatgacct tcctgaagct atccgtccga tcttgcataa agcgtcacaa
    25021 gctgaattag aaaaagacaa aaaaaacaaa aaagatgctt atgatgcatt gaaaatcgca
    25081 aaagaaaaag tgcagttgcg tgagttggaa atgaaaatgg tcaaagccga atacacattt
    25141 gatcgaaata aattgatttt ttctttcaca gcggacgggc gaattgactt tagagaattg
    25201 gtaaaagatc tggccgctgt atttcgtact cgtattgagc ttcgacaaat tggtgtccgc
    25261 gatgaagcaa agataatagg cggaattggt ccatgtgggc gtccattatg ctgttcttct
    25321 tttttaggcg atttcgtgcc tgtatcaatc aaaatggcaa aagatcaaag tttatctttg
    25381 aatccaacaa aaatttccgg tttatgcgga cgcttgatgt gctgtctgca atatgagagc
    25441 gaagaatacg agacagcgaa aaaagaactc cctgactttg gaaaagtaat tgctacacct
    25501 gatggtaaag ggaaagtcgt agggttgaat ctgcttagcc gtatcgttag tattcggctg
    25561 actggacggg aaaatcctgt cgaatatgaa tgggatgaat tgaaagaatt tatccaagta
    25621 ggtgagatga atggataaga gatcattata cgacggattg aatcaattag aatcagagtt
    25681 gagaaataca ttaacagaac ttgttgaaat gaagcatgct ttgcatgaga tcgtagaaaa
    25741 aaatacaact ttggagatgg aaaatcaacg tctgcgggaa cacctgcggg aattgaacca
    25801 agttgcacaa gctccagctg aaaatgtgaa gcaggaactt tctaagtctc gtatgaatct
    25861 tgaaaaaatt tatgaagaag gattccatgt ctgctacgat ttatatggat caagaaggga
    25921 caatgacgag ccttgtgcgt tttgtctaga agtgatctat cgcgaaagcg gtcgatgacc
    25981 aataacaaga ggagactgga gcggagaaat actgctccag tctttttatt aaggagattg
    26041 tgacagatgt ataatcaaaa aagtttcaag ggaaatccgg tatatgggga tttatatctt
    26101 gtaccgacgc caattggaaa tttagaagat atgagctaca gaagtgttcg tatgctgcaa
    26161 gaatccgatc ttatcgcaag tgaggatacg cgtaatacac aaaagttatt gaatcatttt
    26221 gaaatccata caccccaaaa aagtttacat gaacataatt ataaagaacg tgtccctcaa
    26281 ttgattgctt tgttaaaaga aggaaaaacg attgctcaag tcagtgacgc aggaatgcct
    26341 tccatcagcg atcctggaca tgagctagtt ttagcctgca taaaagaagg gatttctgtg
    26401 atctctatcc caggacctac agctgggatg acggctttga ttgcttcagg gctagtgcct
    26461 caaccatttt tattttatgg cttccttcca cgtaagaaaa aagaacagaa agaaacattg
    26521 aaaaagctaa aagaacagac agttacgctg attttttatg agtcacctta tcggatcact
    26581 gctacattga cgaatttctt agaaattttt ggaaatcgcc aagtcgtttt gtgtcgggaa
    26641 ttgacaaagg tccatgaaga ataccttaga ggaagtacgg aagagctact cgcttatatc
    26701 gaagaacatc cagtaaaggg tgaatgttgt ctgcttgtag aagggaattt gttcgaaatg
    26761 ccagtgacgg aagttgatga agagttggga acgttaaagg aacaagtaga agcaaagatc
    26821 gcttcaggcg aaaaaccaaa tgctgctatc aaagcagtag cgctgaaaaa tgggctgaaa
    26881 aaacaagaag tctaccgtca gtaccatgaa ttagactgag atagtataag ttgtctataa
    26941 tgaaagacta atgaggaaat cagctactaa cttttcaaat ctcttgaacg cgaacgaatg
    27001 ttcttgtatg atgaataaga ggtgaggatg atggagctgc aatttccttt acataatgat
    27061 acatcaagaa aaatcattca tattgatatg gatgcttttt tcgcttcggt tgaagaacga
    27121 gatcatcctg agtttcgcgg acatccatta gtaattgcca gacaccccag tgacactggt
    27181 gggcgtggag tagtgactac agcaaattat gaagcaagaa aattcggaat tcattcagca
    27241 atgagtgcac aaaaagcgta tgagctttgt ccgcaagcca tctttaagcc tggcgaccat
    27301 cataaataca gcgatatttc caaacaagta cgggaagtat tctatcgtta tacagatatt
    27361 gtggaaccag ttagtatcga tgaagcgtat cttgatgtga ccgaaaataa aatcaattgc
    27421 aagtcagcca tcaaaatcgc ccgaatgatc caagcagata tttgggagag tgtccagcta
    27481 acatgttctg cgggagtaag ttacaataag tttttggcca aattagcatc agactatcaa
    27541 aaacctagag gaatcacggt agttgcccct caagacgctg tgccattttt aaaagctttg
    27601 ccaattgaaa aatttcatgg ggtagggaag aaaactgtac ctagaatgca tgagctaggg
    27661 atttatacag gaaaagacct atatgaatgc acagaaatga tgttgattcg aaattttgga
    27721 aaaatgggct attctcttta tcgtaaagtc agaggaatcc atgattctcc agtaaacgtt
    27781 acaagagagc gaaaatctgt gggaaaagag catacttatg ggcagccgtt gcaaacggaa
    27841 gaagcagtgc tgactcagtt gcgccaacta gctgaaaaag tagaagaagc actgagaaga
    27901 gtccaaaaac atgggaaaac agtagttttg aaggtcaggt acacggacta ttctactgtg
    27961 accaaaagag tgacattgcc agaatatatc tataaaaaag aagcactctt ttatcaagca
    28021 agccttatat gggaggaaat cttgggagta gaaaaaggaa tccgattgtt agggattact
    28081 ttgacgaatc tggacccgat gacttatgaa aacatcgtcc ttccattatg ggaaaatcaa
    28141 gaaatataaa aacagctttg agagttgaaa ccggaaatcc gttttctctc ccaaagctgt
    28201 ttttatatca agtcttgctt tttgatttgt tcataggttt ctgttgcatc cgtacatttt
    28261 tcccaaatca caacttgatt ggattctaaa gatttttgga cgtcaatgat ccgctggttg
    28321 ctacttccgc gaaattgtag ttttaggtca cgtttgctta attcaaagcg tccgtcaaca
    28381 aggatatcga tttgcgaaag gagttctaat ttatcttctg aatcttgtag caattcatca
    28441 aaggtatagc ctgtccatga ccagatatct tttgtcgtac cgaactcttt tcggatacgt
    28501 cgtacgactt gcagacaaac atctgtattc aaaaaaggtt cgccaccaag taaagttaat
    28561 ccttgcacgt aatcgttgcg caagtcagcg atgatttgtt cttctaattc aggtgtgaat
    28621 ggtttgccat atcgaaaatt ttgtgcagct ttgttgaagc agccttcgca ggcaaataag
    28681 cagccactaa cgtaaagact gttgcggaca ccttcaccat cgacaaaatt aaacggtttg
    28741 tagtcagcaa tatagttttg gctgtagtct tttgctaacc attcttttgg ttttggattt
    28801 ctcataaaaa aacttctttc atttaaggtt caaagatata gctattgaag ataaaatcta
    28861 ctcgaccaca taaataagaa caaactgacc taaatccatt gttcaagaaa gcttgttctt
    28921 attttgatag agggcgttca aagatacaaa gccatcgaaa gagggtggtg aaaaaagact
    28981 tgtcatagcc tcttattctg aataaacggt gttcaaaagc ttgcatctgc agtaataagc
    29041 ccaactaaac gaaaaatatg aggaactatt tttgtttagc tattcttatt acttgatgca
    29101 ggacagcttt ttcacaacct catttcatgt gtttcacacg tgaggaaatt tctttatggc
    29161 ggccatgtac catcggacga gcttgcggat ttcctaaata gccacaagta cgtttgacta
    29221 catcacatgt ttttggatca tgatttccac attctggaca ttcgaaccct cgttctgtcg
    29281 gtttgaaatc accttcgaaa ccacattgat agcaatgatc gattggcgta ttcgtaccaa
    29341 gatacccgat tttgtcatat gcaaaatccc atacagcttc taaagctttc ggattttgtt
    29401 ggagcatagg gtattcacag tagtggatga atccacctga acaatatttt ggataatcct
    29461 tctcaaattc caatttttca aatggcgttg ggtttttacg cacatcatag tggaaactgt
    29521 ttgtataata ttctttatct gtgatatttt cgatgatgcc gaatttttct gtatccaaac
    29581 ggcagaaacg gtcagttaga ctttcacttg gagttgaata gacactgaaa tgataaccat
    29641 attcatcccc ccatgcatct gcattagctt ttaattcttt gacgatatca agtgtgaaag
    29701 cttttgcttc tgggtttgtt tcccattcgc caccgaagaa agctgaagca acttcataca
    29761 atccaatgta gcctaacgat acagtagctc gacggttttt gaataattca ttgacagaat
    29821 cggtacgtga aagacgtttc ccgaaagcac catacatata taaaattggc gcatttgctg
    29881 gaatggcttc tttacaacgt tctacacgat agagaagcgc atctttcatg atttctaagc
    29941 ggtcagacag taactgccag aatttattct gatctccttt tgattcgatc gcgattcttg
    30001 gcaaattcaa tgtaacaaca cctaaattca ttcgtccgac atttacttct tgaccatttt
    30061 cgtctttcca cccttgcaag aatgaacgac agcccatagg tactttgaaa cttccagtta
    30121 attcaacgat tttatcgtaa ttcagaatat caggatacat tcttttcgtt gcacattcca
    30181 atgctagttg tttgatgtcg taattaggat cttcagggtt taagttcaca ccttttttca
    30241 aagtgaagat cagtttaggg aagatagctg tccgcttttc actccctaat ccattgattc
    30301 gaatctgtaa aattgctttt tgaatttctc tttcaaacca gttttctcct agtccaaatc
    30361 ctaatgaagt gaaaggagtt tgtccatttg aagtaaataa ggtattgatt tcatattcca
    30421 aactttgcat agcatcgaag atatcttttt tggtttttgc ttttgcatat tctttttggc
    30481 gttctggcga atcgatccat tcttccgcgt cttttagatg ttttttatag ttcaattctg
    30541 caaaaggagc aagcaattca tctgttcggt cggcagaaca gccaccatat tgacttgacg
    30601 ctacattggc aataatctgt gagatttgtg ctgtggcggt ctggatagat tttggcgatt
    30661 cgacttcggc attgccgatt ttgaacccat tgttcagcat gcctttgaaa tcaatcaagc
    30721 agcaattcgt catcggtgta taaggatgat aatccaaatc atggtaatgg atatcgcctt
    30781 tttgatgcgc atttgctata tgtggtggca acattttcag tccgattgat tttccaacga
    30841 tcccggctgt cagatctcgc tgtgtattga aaacattact gtctttattt gcgttttcgt
    30901 tcacgacagt ttggtccttg ttgattagct tttcaatcga aaagttgata tctgttgctt
    30961 tactgcgagc aaaatctcgt ttggtacgat aattgatgta ctcttctgct aattcatatt
    31021 cgtttttttc tagtaatata tgttccacga tgttttgaat ctcatagatt ttgacatttt
    31081 cagcaaaccg gcttttgatt tcttggacaa ccaagtctgc aatcatttga attttttcat
    31141 aagtaagtgg tgataatgag ccgtgaattt tcttttctgc tttgatcagt gcttcattga
    31201 tcttttgttc atcgaaatca acatggcggc catcgcgttt gatgactttc atctgggatg
    31261 tctctggctg ctgagtaacg acagtttttt cttcataatt tactttcatt atcttcaact
    31321 cctgctaaat tgttcttgtc tatcataaaa caaaatcggg gaaggagcaa ctaaatatcg
    31381 gctatatata gtattcaatg tgctgtataa ttggatttct atactatatg tagtgtatat
    31441 tttattgtga aaaaaggtga aaacttgtag ctggtggatt tgttttttgc atatttaatt
    31501 ttgctgaata aaataattga ataaaatttt ttattcagtc caagtaaaag tgacaaaaac
    31561 ataagagcaa attattcgta gatatgctac tatgcaaata aatagaaatg aaaaatgaaa
    31621 gaggaggaga agaattggaa aagatgatcg aagtgaaaca tctaagtaaa agctacggca
    31681 gcaaactttc tcccgtcaaa gccttagata atatctcatt cacagtagaa gaaggcgagt
    31741 ttgttgggat tatgggccca agtggtgcag gaaagacaac gctgatgaat atcttgtcca
    31801 cgatcaattt gcctacgatg ggcagtgtct cgatccaagg aaaagaaatc acaaaaatga
    31861 aaaacagtga gctcagtgac tttcgtcgaa aaaaactagg attcattttt caagagttca
    31921 atttgatcga taccctaaat gcaaaagaca atatcctatt gcccctagca gttgaacgga
    31981 tgactaaaga ggaaatggaa aagagagtaa gacatgtagc tcaattgttg aatatagaag
    32041 aactgctcaa acggtatccc gatgaacttt ctgtcggaca gagacaacga attgcagctg
    32101 ctagagcact tgttgttcag ccacaagtga tttttgcaga tgaaccaact ggctctttgg
    32161 actcgaagtc ggctacagaa ttgttgaact acttgaagac catgaatcaa aaagaaaaag
    32221 caacgatact gttagtcacc catgatccat atacagcaag ctactgcgat agaattttat
    32281 ttattaaaga tggtgtgatt ttttctgaag ttgtcagaag agggacaaga agagagttct
    32341 ttgagaaagt aatagacatg caggcgacga ttggcggagg aggaaaaatg aatgctgtat
    32401 aaactagccg ttaaaagttt ttttcggcag tcacgaggct atcttgttta ttttttcagt
    32461 ttgactttat ccgtaatgat ctattattcc ttcagcgcaa tgacctacga tcaatcttta
    32521 gtcagaagag caagtcaaga tacttcgata gatggtggat tgagttttgg tggatttatc
    32581 attactgttg ttttgctttt tttcgtattc agtgccaacc gatttttctt gaatagaagg
    32641 caaaaggaaa taggcatcta tcagcttttt ggtatgaata aactgcagat atcaggtata
    32701 tatgtgttag aaatcatgat aattggattg ttcgcctgta tttctgggat attactcggt
    32761 attatttttt ccaaactctt ttcaatgatt ttggttcgaa tgatggatat ggatcttact
    32821 agtccatttt ttatctccat tccatcagta gtagatactt tatttgcttt tttcatcatc
    32881 cttttagcag tatctgtata ttcaatatgg aaaatatggc gctatccaat gattcgaagt
    32941 tttggagaaa aagaacaagc agatagttca acaatgcgct tcaggacaag gcaccgatta
    33001 ctcgcagtca tcgggttact acttttaacg agcggatatt ttggagctag tcattttagg
    33061 gaaatcactt catggatgat cagttatcat tatcttgata cattagtttt cttttttcct
    33121 tttttaattt ttttcgtttg tgtggtcggt acttatttgt ttttctgtta tacatttcgg
    33181 ttatttttga tcatattgag taaatggaag atttattact atggtatcaa ttttttgata
    33241 atgggtaaca cgcaagttca tttgctcaaa agttggcgta caaattctct gattacagtc
    33301 attctcggaa tttctttaat gacaattggc ggcacggcta gtatctctac tattttatcc
    33361 taccaggaga aagtttcctc cccgatggac tatcagtttg atgttgagac agagaaaaaa
    33421 atcaagccga ttctagcaga ggaagggcag aagataacta aagaaatcac cttgcattat
    33481 aaagtcattg ggagtatcta tagtcaaaat ctcgaagaac ctatgtttca aactgctaat
    33541 ctgatcacgg aaacacaata tcaagccttc agaaaagtta atccagattt gccgaacatt
    33601 tctttgaaat cacctggtca tactgttttg cttgatcaaa tgcaaactct ttttcggaat
    33661 atttcattat atggatctag tattggactg ccagataatc aagaattgaa gattcaacaa
    33721 atgcttccaa gtgtattagg tgacgaaaca atggtatatc taagtcctgt actgattgta
    33781 gatgataccg tttttgaaaa agcaaaaggt gtggattatc aagtagtcaa tgtagatgta
    33841 tcaggtggaa ataatgaaaa aatagatgaa cgactgagca atgacctgtc gataaagtgg
    33901 ctcaatgctg tttattattc ttatgatatc gtaaatggaa gtctacaagg agaaattagc
    33961 acaaagaaac ttccggatga ccaaatgaag gaagcacaat ttagccaaga aagctctcgt
    34021 ttgaatttct cttccagcta ttcgaaattg cgtgcagtta atcggcgaat cggtatcaat
    34081 atttttgtca cactatttgt cgggatgatc gtgattattg ctactggtag tattttgaca
    34141 gtccggcaat tagcagaagc agaggaagaa aaagaaaatt atcacctatt gactaagctg
    34201 gggattccac aaagaaggat cagacggatg atcttcgagc aaaacgcact taccttcttt
    34261 ccacccatga tattagggat cactcacgca gtatttgcaa tcaatgtctt cactcagtat
    34321 ataaaaactg ccgattactg gttggcttat cttgtgagtg gcttattgat ccttatctat
    34381 cttttgcttt atgtcattac gagtcagtta tattgtcgga ttatcgagga atgatatacg
    34441 gaataagaca agataataaa tagaactaaa ttttgaatac catttatttg gaataagagg
    34501 ttgtgacacg atttttgtca caacctcttt attttttata ttttttaaaa gtacgagaaa
    34561 ttataaagaa aaaagcagtg atttgatgtg ctatttttat aaaagctatg tgacaaaact
    34621 gttagtaaaa aaacggtttc tgtaagctag acacatgttt ctttttgtca aaattagtta
    34681 cactttgtgt gaggttatat gaggagggaa tccaatgaac aaatggcgtt ctaatccaaa
    34741 attgaattat tggggaaaat tcatcattcg aacaattttt tatagtgcag tactgctgtt
    34801 cctgatttat ctgtatcact ataaaaatat tcaaggagga acttttatct ataacgaatt
    34861 ttaggaggaa gagtatggaa atcaaaacga ttattgaagc aatcgatgat tggggaataa
    34921 atgaacctga tcgagttgct tatcaggcgg atgagacgca tacttttggt gaattgaaac
    34981 aagcatcaga cgcacttgct tattatttag aaaaaaaggt agaaggcgat ggaccaattg
    35041 tcgtttttgg caatttggag tttgaaatga ttgtctcatt tctaggggtt gtcaaatctg
    35101 gccatgccta tttgccgatt gaagagcata cacccaagga gcgtatccta tcgatctttc
    35161 gggtggctaa accatctatg gtcatcagta tcggggactg gatagaagat attccttcgg
    35221 ttcctgtcat aacaaaaaaa gaatttcaag aaatcaagaa gataccagta ggattttatc
    35281 ccagaaatag cgtaaaaggt acagaaaatt tttatattat ttttacttct ggtactactg
    35341 gagaaccaaa aggcgtacaa atcagtcatg ataatctagt cagctttgtt caatggacga
    35401 tggaagactt tgggatcaag cctggtatgc atttcttagc ccaagcgcca ttttcttttg
    35461 atttatcggt attttctatt tatcctgcat tagtttctgg cggaatgctg aagccgttaa
    35521 ataaagcagt tgttcaagac tttcgtcaat tattcgcgac attgccagcc ttgaagttga
    35581 atgtgtgggt ttctactcca tcatttatgg atatttgctt gatggaacct acattcaatg
    35641 gagaaaatgt gccggaattg gacatgtttt tattttgcgg agaagaattg acgaaaaaaa
    35701 ctgcagaaag tctacttgat cgattcccaa atgcacggat atataatact tacggtccaa
    35761 cagaagcaac tgtagctatt tcaagtattc agattgacca gcatgtacta gatagttatg
    35821 accgactacc gattggctac gtaaaaaaag acacgaaagt ttctattgtc caagaaggta
    35881 aacctgtttc aaaaggagaa acgggtgaaa tcattattgc aggaccaagc gtatcaaaag
    35941 gttacctgaa caatcccgaa aagacagctg ctgcgttctt ttgtcaaaat gacttagcaa
    36001 gttaccatac aggggatgca ggtagactag atgaatatgg gcttttattt tatgaaggac
    36061 gtatggatca gcaggtcaaa ttacatggat accggattga actcggggat atcgaacatt
    36121 atctgctcca agacaaccga atcaaacaag ctgtcgtcgt accaaaatac caaggaacaa
    36181 aagtacagca gctggttgct tttgtcgtat tagaaaacaa aacgaaacag ccggattttc
    36241 agttgactaa atctatcaaa gaacaattac tagaagttgt aatggattat atgattcctc
    36301 agaagttcca ttatgtcgat ctgctgcctc agacagttaa tggaaaaatc gatcgaaaaa
    36361 aattaacagc tgaggtgaat cctgaatgat gttacctcat atgatccctt atgcagagcc
    36421 gttttatttt tttcttttag ccattgcgct tgtaccgatc gttctatctt tattgatatg
    36481 ggaaaaaaga ttaccagttt atcaatcagc agtgacactt ttctttttat ttgtcagctt
    36541 tggaggtaat tattggcaac agggagcggc gctgattggg tatgttttgt ggcagacgat
    36601 acttgtatgg ggctattttg tttatcggca aaggaaaaat cagacaggat ggttttttgc
    36661 cgccgttatt ttagcgataa ttccactgtt tttaacgaaa gtgactcctt tttttgaaca
    36721 tggaaaagca tcgttacttg gttttttagg aatctcttat ttaaccttta aatctgtaca
    36781 aatgatcatg gaaataagag atggcatgat caaaacatat aagccatttc gttatatcca
    36841 gtttctgctg ttctttccaa caatctcttc tggaccaatc gatcgctata ggagatttga
    36901 aaaagatcag ctccatccgc ctgttcgtga taaatatgtt gatcttttgg gaaaaggcgt
    36961 ccaaaatatt tttgtcggtt ttttatataa attcattatc ggttattatt ttggtcaagt
    37021 actgcttcct gtagtgggac gcattgcctt acagcatggt ggtatttcat gggcattagt
    37081 aggttatatg tacgtgtaca gtatgtattt gttttttgat tttgctggct atagcttatt
    37141 tgcagtcggt acaagctaca tgatgggata tcagacacca atcaatttca ataaaccttt
    37201 tttatcatgg aatatcaaag aattctggaa tcgttggcat atgacgctgt ccttttggtt
    37261 ccgtgattat gtatatatgc gattgatgtt cttcatgatg aagaaaaaat tttttaaaag
    37321 caagatcgta atgtcaaata tcggttattt tgctttgttt cttctaatgg gtatatggca
    37381 tggattgacg tggtactaca tcgtatatgg actgtatcat gcttgtctga tctgtctgac
    37441 agatgcatgg atccgattta agaagaagca taaagagcag ttgccttcta acaaatttac
    37501 gcatggctta gccgtatttt tgacatttca agcagtatgt tttagcttcc tgattttttc
    37561 aggattttta gataaacttt tttttagcta acgaatagtg acatattaat ttatataaca
    37621 aaggagaaaa ggaaaatgga agaacaaatt ttatcaatct tagaagaaat aacaggaaca
    37681 gatgaagtaa gaaaaaatcg tgatattgat ctatttgatg aagggttgct tgattcttta
    37741 gcatctgttc aattattagt cgagctagac ggagagctgg atatccaagt ccctgtatct
    37801 gaattcgagc gagaggattg gtgcacaccg aataaaatca ttcaacaagc aactgcattg
    37861 aagggttgag tatgaaaaag aaactttttg ctattttcgg cccggttgtt ttagctgttg
    37921 gcttactgtt tgtgtttttt acctcctcct atcaagtaga tatctctaat ccagaaacga
    37981 ttagacgtgc ctcttcttcc atgtcagtga acgtgttgaa aggagatgcg ataaaaaatt
    38041 atgcattatc tgaaaaacaa tatattcctt tttttggctc aagtgaatta agcagaatca
    38101 gtccatttca tccgtctgtt ctggcagaaa aataccagcg aaactatcgt ccatttttgc
    38161 tgggagcacc cgggacacaa tcgttaagcc aatatatgat gatgcgttct gcaggagatg
    38221 ctatgaaaaa caagaaagtc gtctttatta tttctcctca gtggttcgtt aaaaatggtg
    38281 taaaaactga ttactttaat acgtattatt ctgaacttca aacatacgac tggttgtttt
    38341 caatgaagaa agtaacgcct gctgatcgct atttagctag aagattatta actttctcaa
    38401 aagtaaaaga gaatgatacg ttgacggcga ttctgcaaac gatcaaaaaa gggaagctac
    38461 ctttacctga atctttgaat cagctgcgca gccaatggaa catgctgaag agagaggatg
    38521 aagtattcag caatattggg ttgaaagatc gacagcaaaa aatcgatcat gagtcaaaac
    38581 gattaccaaa acaataccaa gaaacagaat tatccatttt agcaaatcaa attggagaac
    38641 gagaaacgac gaataatcca ttcgggttga aaaacgattt ttatacgcat cgtatccgag
    38701 cccacgagcc agagctcaaa cagtcacaaa aaaattggga ttatcgtttt tcgccagaat
    38761 tttctgattt tcagctggtc ttggatcaat tagcaaaaaa ccataacgaa gtattgttca
    38821 tcatcccacc ggttaacgag aaatggagcg attataccgg actatctcaa gaaatgttac
    38881 aaggatttgc caaaaagatc aaatttcaat taaatagcca aggattcaat cgaatagctg
    38941 attttgtcaa tcaagcgggt accaactatt ttatggaaga cacgatccat ctaggctgga
    39001 aaggctggtt ggctgcagat caacagatca gaccgttttt agaagaaaat catattactg
    39061 ctagtaagta tcatcttgac gatgcttttt ttagcaaatc ttggcaacat caaataccag
    39121 ataaactaca attaaaataa agaaaacagg cgagtgttgc tcgcttgttt tctttatttt
    39181 tgaatattct gaataaaaga taaaaatacc aagtttgcct gaacaaaaat cataagcaat
    39241 ggtataatca caatatgaat atagaaatgg gggaaaacat ttggatacaa aagaagaaca
    39301 gctacttatt gatttaactt ctgcaaaagg agtacctgga aatgaagaag aggtaagaga
    39361 agtattcaga gaatatgcca aaccattcgc tgatgatatt ttttatgacg gtttaggcag
    39421 tgtgattgcc aaacatggtg ctggcggagg ccccaaggtc tttatttctg gacatatgga
    39481 cgaagttggt tttatggtaa caaaaataac cgaaaaagga ttcttggaat tccaaactct
    39541 tggaggttgg tgggggcaag tcatgcttgc tcagcaagtt gaaatcaaaa cacgtgaagg
    39601 gaaaatcgtc cacggtgtga ttggttccaa accaccacat gttttaacac ctcaagtaag
    39661 aaataaacct tatgaaataa aggatatgtt cattgatatt ggcgcatcaa gccaagaaga
    39721 agccaaagag tggggcatac gtcctggaga tatggtcact ccatatattg aatacaaacg
    39781 aatgaatggc agtaaatatt tactggcaaa agcatgggat aatcgtatcg ggacagctgt
    39841 ttctctgcga gtattagaga atctatctaa agaagcacac ccaaatgttt tattcgcagg
    39901 aagcgatgtg caagaagaag taggcttgcg aggtgctcga acaagtacac accttgtaaa
    39961 tcccgatatt gcttttgctt tagatactgg tacagcagga gacactccag gaatgacacc
    40021 aaaagaagca gattcgattt taggaaaagg cccacagatt ttgatttttg atgcatctat
    40081 gatcccgcat aaaaaattat tgaattttgt tattgatgta gcagaggaaa tggatattcc
    40141 attccaatat acagtgattt ctggcggagg aactgatgca ggacaaatgc atttgacaag
    40201 agatggtgtt ccgtctgtag ccattaccgt tcctgttcgt tatctgcatt cccatacatc
    40261 agtgattcat gaagatgatt atttgaatac agtgaaacta gtcacagaat tagtgaaacg
    40321 gcttgatagt gaaacagttg aaaaaattcg gagttatgaa taatgaataa tagaatacct
    40381 atttctgaat atcggaaaaa agcacgagtt tctttggaaa atcaatgggg aatcaatact
    40441 tggcttgttt tcttatctat aatatttacg agcgtcatcc agaacttttt tgacggtttc
    40501 agtccttttc cggaagaaag catgcagcag cacttattga gttttctagt cgataattta
    40561 cttttattcg cattcaacta tgcattgttt tacattgcgc tagtagttgt acggggtggc
    40621 agaccaaaaa gtaacctttt attttcagtt ttccaaagaa agtattttgg ttcgatactt
    40681 ggcatcaatt tgatcaattc agtcatcaac tggctactca acagtttaat ctttctgccc
    40741 atgtttttaa tcagcggagt gagtacttat atgcagctgc ttttcagttc aaatgcggta
    40801 cctacgggtg tcatgccaga agattttctt gatatcagct ttgttttatc gatgataggg
    40861 atgatttttg tttcagcact catcatgagt attgttggcg gtttattcca atttgctgca
    40921 tggacaaagt tcgactatcc tgatttgtcg gttattcaat gtttgaaata tggctggttt
    40981 ttattgaaag atagaattgg tacgtatatt ttgttgcagc tgtcttttat cggctggtat
    41041 ttgctaggag caatcgcttt gttcatcggt cttttgtggg tcattgttta tgtgaatgtg
    41101 tcagttgcag aattttatga acaagcacgg attgaaaaag gaggtccaga cgcctatttt
    41161 acttagcatg taagcagttt attcatcaaa aaaataactt ttgtggtagg ataaatcttt
    41221 gagggggaat gtacgatgaa attaactgtt ttaggatgct taggagcgta tccttataaa
    41281 aatcaaggga caacaggtta tttgcttcaa tctgacgggt tcaatttgtt gatcgatgca
    41341 ggtagtgcta cgctgatcaa attacaagaa caccttgatc cacttgatct agatgctgtg
    41401 atccttagcc attatcatca tgatcatatt gctgaccttg gtgtattaca gtattactgg
    41461 caacttcatc ctaagagaaa tccggagaca ttgctttcaa tttatggaca cacaaaagat
    41521 tccattcact ttgaagaatt gacgttggaa aatgtctcaa aaggacatcc ttattttgaa
    41581 gctgaagaat taaaaattgg tccttttctg attactttta tggaaacaat ccatccagta
    41641 gtatgttacg ccatgcgtat cgtagaagaa acaacgggga aagtattcgt atttacaggt
    41701 gattcaggtt atttggaaag tttcgctgat tttgcgaaag atgctgattt gtttctagca
    41761 gatacctatc tttttgaagg aaatgaacat catcatgccc atttcacttc aaaagaagct
    41821 ggagaacttg cgaaatcagc taacgtaaag aaacttgtac ttacacacct acctcagttt
    41881 ggtgatttag aacaattgaa aaatgaagcg caaaaggcag caggcaaagg gattgatata
    41941 gaacttgctg cagttgacaa agtgtttaac atttaggagg aagaacatga tttttgtacc
    42001 aaatgaaaac cacgacccaa gaatcaattt agcaattgaa caatatttgc tgcaagaaat
    42061 gcctttagat gaacctattt tgctctttta tatcaatgaa ccttcaatca tcatcggcag
    42121 aaaccaaaat acgcttgaag aaatcaatcg agattatgtg gaagaaaatg gcattcatgt
    42181 tgtccgtcgc ttaagtggag gcggagctgt ctaccatgat tttggaaacc tgaactttag
    42241 ttttatcatg cctgatgatg gggattcatt ccgtgacttt gcgaaagtaa cacagccaat
    42301 catccaagca cttcatgaat tgggtgttgc tggggcggaa ttgaaaggcc gaaatgatct
    42361 agtcattgat ggcatgaaat tttctggcaa cgcgatgtat gctaccaacg gtcggatgtt
    42421 tgctcatgga acaattatgt tcgactctga tatcaatgaa gtagtcaatg cattaaaagt
    42481 aaaaaaagac aaaatcgaat caaaaggaat caaatcgatc cgttctcgtg taacgaatat
    42541 caaaccattt cttccagaag aaaagcaaaa aatgacaaca gaagaatttc gtcaagaaat
    42601 cttgttgaaa attttcggcg tagagtcagt agaagaagta aaaacgtacg aattgactga
    42661 tgaagattgg aaaaaaatca atcgaatctc tgaggaatat tatcgaaatt gggattggaa
    42721 ttacgggaag tctccagatt tcaatttctc tcgccaaaaa cgtttttcta tcggttcgat
    42781 tgaagtccat ttgaatgtct cagaaggaat gatcaaagaa gcaaaaatct ttggcgattt
    42841 cttcggacta ggagatatct ctgacgtgga aaaaaaattg gttggacaga aatatgataa
    42901 agcatctcta tcaaaaatag tcagccaaat tgatgtgaag aaatattttg gtgcgataga
    42961 accagaagaa ttgcttacct tactttattg aaaataaaaa atagcggaat ccacatatat
    43021 ggattccgct attttttata caggattcgg gtaatttcga gagagttgaa cagtgatccg
    43081 atcaatgaaa gtatcttttt cctgcgttag tgttcctgtg taacgatccg ctacgtcttt
    43141 catcatcatt aagtcaaaac gttcctgatc atctaattct tctgtgatgc ctcgactaaa
    43201 taggtttgta tcgtaatgtg cactatgttc gcaacaaatg acgaaatgtt cctcttgttc
    43261 gtgtatcgac aaataaattt ttcgatacag tggattttcg atggcatgag tttctctaaa
    43321 ggaatgctct aaagcgtgga tcaaaagttg agccagatcg tcatcgttga taggaagttc
    43381 ttcgggaaga tctgcttgga aggttatctg aatattccgt ttggcagcta acttctggta
    43441 acgcgctaag ataagatttg tcacctggtg gttgcaaaaa gaacacagca tttcgaaatt
    43501 ttttgcttct tctaatatct tttccacata gtttttagct tttgtttggt ccgtatgcat
    43561 taaatcttgc agattctcca tctcttggac aaattccagg cgaagtgtat ttacttcttg
    43621 gatatgctgt cgaagctgct cataatgttg ctccaacaaa tcatttttga tttttaagaa
    43681 atctacttgt ctccgatctt tgtcggtatt taagatgtga tcgattagat tgtagctgat
    43741 aataacgatt agaatgataa tatataaaat cgtagaccaa ttgatcgttg tttgatagat
    43801 acctaatgcc gtttggatgt aaatcaagca atggataatg gctaccaaga cgatccaagg
    43861 tgtacaagct acataaaaac ggttattctt atatgcttcg ccaatgcatg caagtgaagt
    43921 gactaaagtg cttataacac tagcaatatt agcaatcggc attaattcag gaagttctgc
    43981 aggagtaaaa gttgcataaa gcagaacgcc gataaaaatc aaaagttgga acgtacaaaa
    44041 aattccgtac cattttttat agtaaaacat tcggctccaa tagtagcaga tgatgaaagc
    44101 tgacgttaag ataataaata aatgagataa aaaagaatga acgaatggtt caaaaagaat
    44161 accacttaaa atatcttctg atacagcttc aaatcctaat gccaaagcaa agcaacttaa
    44221 gagaataagt gagtattcaa gacgtttttg tttatacatc aagtagatcg tatagaaaaa
    44281 ggtccctata gcgataaaaa cagcgattat catcgtcaat acttgcggca ctgattgtga
    44341 ataaataaaa ctaatcaatg gtccagttgt tcctagataa actttcggtg gcagtccagc
    44401 atagttctga taaggagatg agactgtaag ggtcaatttt tttccgatat aatttgctgg
    44461 taaatctatc acagccaatg agagtccggg attgctttct tcctgataat ctttccgttg
    44521 gtataaaatc ttttcgccta gatatacagt aatccattga tggtttcctt tgattagtaa
    44581 atttgcttcg tccaacggtt tttcaagtgt cgtttccata atgaatgttt cgtctttatc
    44641 cacggtagga atcgtacgag tgtacttgct gtcaaactta aaatcaggat catcttttgt
    44701 atagaaaacc cacgaatctt ttatttcttt catttgattg ctgtccgcag gagaaaaaat
    44761 aaaataaaag aaataagcaa ttcctgttaa aaataacaat gataatataa tgattatgct
    44821 ccactttata cgtaaataaa aagattcttt tttattatat atgttattaa aaaaagac
//
LOCUS       DAZKPE010000015        44395 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000015 DAZKPE010000000
VERSION     DAZKPE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.015"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            395..715
                     /locus_tag="ACG930_000946"
     CDS             395..715
                     /locus_tag="ACG930_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFQ0518122.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            869..1774
                     /locus_tag="ACG930_000947"
     CDS             869..1774
                     /locus_tag="ACG930_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518123.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1771..2544
                     /locus_tag="ACG930_000948"
     CDS             1771..2544
                     /locus_tag="ACG930_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0518124.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2725..4149)
                     /locus_tag="ACG930_000949"
     CDS             complement(2725..4149)
                     /locus_tag="ACG930_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFQ0518125.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4360..4806
                     /gene="nrdI"
                     /locus_tag="ACG930_000950"
     CDS             4360..4806
                     /gene="nrdI"
                     /locus_tag="ACG930_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFQ0518126.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4871..6853)
                     /locus_tag="ACG930_000951"
     CDS             complement(4871..6853)
                     /locus_tag="ACG930_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFQ0518127.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6867..7763)
                     /gene="murQ"
                     /locus_tag="ACG930_000952"
     CDS             complement(6867..7763)
                     /gene="murQ"
                     /locus_tag="ACG930_000952"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFQ0518128.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7766..8827)
                     /locus_tag="ACG930_000953"
     CDS             complement(7766..8827)
                     /locus_tag="ACG930_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFQ0518129.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(9038..9565)
                     /locus_tag="ACG930_000954"
     CDS             complement(9038..9565)
                     /locus_tag="ACG930_000954"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0518130.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(9632..11134)
                     /gene="eat(A)"
                     /locus_tag="ACG930_000955"
     CDS             complement(9632..11134)
                     /gene="eat(A)"
                     /locus_tag="ACG930_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFQ0518131.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11392..12513)
                     /locus_tag="ACG930_000956"
     CDS             complement(11392..12513)
                     /locus_tag="ACG930_000956"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFQ0518132.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12639..13580
                     /locus_tag="ACG930_000957"
     CDS             12639..13580
                     /locus_tag="ACG930_000957"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFQ0518133.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13730..14626)
                     /locus_tag="ACG930_000958"
     CDS             complement(13730..14626)
                     /locus_tag="ACG930_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFQ0518134.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14895..16235
                     /locus_tag="ACG930_000959"
     CDS             14895..16235
                     /locus_tag="ACG930_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0518135.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16453..16896
                     /locus_tag="ACG930_000960"
     CDS             16453..16896
                     /locus_tag="ACG930_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFQ0518136.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17400..18818)
                     /gene="nhaC"
                     /locus_tag="ACG930_000961"
     CDS             complement(17400..18818)
                     /gene="nhaC"
                     /locus_tag="ACG930_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFQ0518137.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19221..20444)
                     /locus_tag="ACG930_000962"
     CDS             complement(19221..20444)
                     /locus_tag="ACG930_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0518138.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20475..21314)
                     /locus_tag="ACG930_000963"
     CDS             complement(20475..21314)
                     /locus_tag="ACG930_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0518139.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21331..22011)
                     /locus_tag="ACG930_000964"
     CDS             complement(21331..22011)
                     /locus_tag="ACG930_000964"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFQ0518140.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(22013..23086)
                     /locus_tag="ACG930_000965"
     CDS             complement(22013..23086)
                     /locus_tag="ACG930_000965"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518141.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(23142..23380)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23423..23656)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23733..24404)
                     /locus_tag="ACG930_000966"
     CDS             complement(23733..24404)
                     /locus_tag="ACG930_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0518142.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24491..27139)
                     /gene="mgtA"
                     /locus_tag="ACG930_000967"
     CDS             complement(24491..27139)
                     /gene="mgtA"
                     /locus_tag="ACG930_000967"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFQ0518143.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(27481..27655)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            27828..28265
                     /gene="ndk"
                     /locus_tag="ACG930_000968"
     CDS             27828..28265
                     /gene="ndk"
                     /locus_tag="ACG930_000968"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFQ0518144.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28287..29153)
                     /locus_tag="ACG930_000969"
     CDS             complement(28287..29153)
                     /locus_tag="ACG930_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0518145.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29313..31406)
                     /locus_tag="ACG930_000970"
     CDS             complement(29313..31406)
                     /locus_tag="ACG930_000970"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0518146.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32155..32778)
                     /locus_tag="ACG930_000971"
     CDS             complement(32155..32778)
                     /locus_tag="ACG930_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518147.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32937..34334)
                     /locus_tag="ACG930_000972"
     CDS             complement(32937..34334)
                     /locus_tag="ACG930_000972"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0518148.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34366..35337)
                     /locus_tag="ACG930_000973"
     CDS             complement(34366..35337)
                     /locus_tag="ACG930_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0518149.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35711..36136
                     /locus_tag="ACG930_000974"
     CDS             35711..36136
                     /locus_tag="ACG930_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518150.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(36624..37325)
                     /locus_tag="ACG930_000975"
     CDS             complement(36624..37325)
                     /locus_tag="ACG930_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0518151.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(37341..37781)
                     /locus_tag="ACG930_000976"
     CDS             complement(37341..37781)
                     /locus_tag="ACG930_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFQ0518152.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37781..38356)
                     /locus_tag="ACG930_000977"
     CDS             complement(37781..38356)
                     /locus_tag="ACG930_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFQ0518153.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            38597..38806
                     /locus_tag="ACG930_000978"
     CDS             38597..38806
                     /locus_tag="ACG930_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFQ0518154.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(39204..39716)
                     /locus_tag="ACG930_000979"
                     /pseudo
     CDS             complement(39204..39716)
                     /locus_tag="ACG930_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(39842..40543)
                     /locus_tag="ACG930_000980"
     CDS             complement(39842..40543)
                     /locus_tag="ACG930_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0518155.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(40651..42094)
                     /locus_tag="ACG930_000981"
                     /pseudo
     CDS             complement(40651..42094)
                     /locus_tag="ACG930_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(42108..43973)
                     /locus_tag="ACG930_000982"
     CDS             complement(42108..43973)
                     /locus_tag="ACG930_000982"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0518156.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(44094..>44395)
                     /locus_tag="ACG930_000983"
     CDS             complement(44094..>44395)
                     /locus_tag="ACG930_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0518157.1"
                     /translation="SIISKFFGIVFDEESLNYQRIITHLQFFAQRYLKGEGSDEQDEF
                     LYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVSEKKSIQS"
BASE COUNT        12827 a         9347 c         7694 g        14527 t
ORIGIN      
        1 atagacacta tttttaaata tttttcgtta tttttttatc acaaaaatta tcttacttat
       61 tgtaaggtaa agcttttttt aatttattgc ccgataatat atagaaataa ggtctagtta
      121 ctgttttttt taaatgatta ataaataaca acttctttct atgaaattgc aaagcattca
      181 tcttcttttc cgctaacgat atatccgtca gtgcttggta cactttacta aaaagtatga
      241 gattgccgat atctggatag gtgtgctata ctacagaaaa agatatacaa tctgccaccg
      301 ggtaggataa agaggatgat cattccatta ggtctttgaa gggatgattt tcctcttttt
      361 gtgtattttt ttatagttaa ggaggaatgt aagtatggca tggatggaat taatcatagc
      421 aggaattttg gaagtattct ggtcaacgat gatgaaatgg agtgatggtt tttctaaaat
      481 caattattct ttttacacag tgattggcat gattgctagt ttttactttt tgtcaaaggc
      541 aatcaaaagt ttgccgatga gtctctctta tcctatctgg acagggattg gcgcagttgg
      601 ttcggtcata attggtgtgg tcttgtttca tgataagctg aatctttcca cttggttctt
      661 tgtggggatg ctactcatca gtatcattgg catcaagatt actagcggcc actagacact
      721 tggaataagt actgatcaga aaaaataagc ctttttattt aatattcaat ttttttatga
      781 aaaaataaga aataagtcca atgacctagc gacttctcca ctcatcaggt gtatgcttgt
      841 actatctata gaaaaggagt gaatattttt gaaaagtctt tcggtccaag aattatccaa
      901 gaactttggt cacaaacaag ccctcagcga tgtcagtttt agcttatccc ctggcaaaat
      961 cgttggatta gtaggtccta atggcgctgg aaaaacaacg atcatgaaag ctattttagg
     1021 actgatccat tactcagatg gaacaatctg tattggtgaa aatgagattt ctccctctag
     1081 tcataaaggg ttggaacaag taggagcatt gatcgaatac ccgggtatct atccattctt
     1141 aacaggctat gatcatctga agttattctc tgaaaccaac gatgtatctg ctatcgacac
     1201 tatcgtgaat cagctcaaga tggaaaagta cattcacaaa aaagcgaaat cctactcgtt
     1261 gggaatgaaa caaaaattgg gaattgctct tgccttactg aaccatccgt ctatcgttat
     1321 tttagatgag ccgatgaacg gtttggatcc acaagcaaca agagatgtgc gaaaaatcat
     1381 taccgacttg gctactcagg gcacctcttt cttgatctcc agtcacttac tcagcgagct
     1441 tgaaaaaatg gtcgatgagc tgatcctgat caatcaagga aagatcatca aacaatgtac
     1501 aatggctgaa ttgaaccaaa cagcgcaaga tttcatcgtt atctctacaa caaatgatct
     1561 agctgctcga acgatcttga cagaagctgg atatactttg gaagatcctg ataaaatcaa
     1621 gcttttaaaa gaaaacgaag aattattagg aaccgtgatc cagctattgt ctgcacaaaa
     1681 tatccatgtg acagacgtcc agcatctgac gaatgatttg gaatcttctc tattggaaat
     1741 tctggattca gtaaaggggg aagaagaaaa atgacattgc ttgtaaaaca agaattattt
     1801 aaattgatca agaaaaagtc aactgctgtt ttatctgttc tattagttgt tttgctcata
     1861 ggaacagcac ttctagccaa aaaatacacg acgatcattg atccagttga aatgactgct
     1921 cagcttttta gtgccacatc ttggattgtc tttatcatga ttgcagctgc aagcacgatc
     1981 atttcgatgg aagcacaata tggtacattg aaaaatctcc tttatcgaaa gtattctcga
     2041 ggagaaatat tagtaagcaa atggatcaca ttagttattt attctgttta tttatacctt
     2101 ttagctatta ttgtcactgt gttgatgaaa ctgattcttt tcccttcgat ttccttcacg
     2161 gagaaggttt ctactggtca aacactgatc caaagcttgt tcacttatac tttgggtagt
     2221 tatatcggtt tatggctgat tttaagttta gtgttgatga ttgcttgctt tatcaatagt
     2281 tccggcgcat ccatctcagc aggaatcgtc ttttattttg cttcgtcaat catatctggt
     2341 atccttattg cactcatcca aaaatgggag tggatcaaat ggaatccgat cagtatgttg
     2401 aatctgcaaa accaaattgg aaacgaagag atcatgaagc aattgactca tctttctact
     2461 aatcaaatgc tattcggtaa tttagcttac atcgttttgt tcttagcatt aggatatctc
     2521 gtatttaagc gaaaaaatgt atgatgactc atcaaaaaag aggctgtgaa agagacgttc
     2581 agccttattg ccgattggct gtctcttaaa caccgtttat tctgaaaaag gagctgtgac
     2641 aacatttgtg tcacagctcc tttcctagta tgtttttgaa taaacgacag gctcacaacc
     2701 tctctttata cttcttttat acttctatac gtgaagcatc ccagtggcaa ataaaaccat
     2761 tgcaatcact ccgaccatcg tcacacctat aagtaaaatc ttatctaagt ggatatgttg
     2821 tacaggctcg ttttgctcct tacgtgcttt gaggtaaaaa taaatgcctg gcaagaaaag
     2881 aacaagaaca agcattactt cattaaaggc tacgactagc atagcccata cttgaaaggc
     2941 acttgctaaa agccctacta aaaattggac ccattctttc cgctgataag aaagtttcat
     3001 ttggtacaat cctaagaaaa gccacgtgaa gaaaatagct gctgtaccaa gtgtgtaagc
     3061 aaagttataa gcactgtcag tgaataataa tgaaagtaaa aagacattcg tacataacgt
     3121 cgtcaatacg atagcataag ttggtgcccc atttttgttg agttttcccc atgctttagg
     3181 caaaagtccg tcttcagcca tgtttcccat tgtttcaatc ggtaagatcg tccatgagag
     3241 ccaaacacca actaaagaaa tgatcaaacc gccgttgatc acgactgctc cccatttacc
     3301 aaccatcatt tcaaacacat agcccatagc aggctgcgcc ttgatcgttt gcagctgatt
     3361 catcgtcatt gtcccatatg gaagcatgga aaccaagacg taaataataa tcaagccgaa
     3421 tatccctaga atcgttgctt tcccaacatc tgattgtttt tttgctcgtg aacctacgac
     3481 agaggctcct tcaataccaa caaataccca aagcatcacc atgatgcaac tcaatacttg
     3541 actggaaaac gggatcggct gtccattcgc attcaatata atgtcgctag aaaagttatc
     3601 aatgaattgt tggatcgaaa acgtgctgat agctactaca ataaataaaa ataatggcac
     3661 taatttacag aatgtgacga tagcattgac gaaactagca ttttcgactc cccgattcac
     3721 tagccatgca tatccccata aaaagactgt actcatcacg atcgatgcca gattttgccc
     3781 accttcaaat actgggaaga aatatcctaa tgcgctcatc aacaatgttg caaaagctac
     3841 gttgcctaac cagcatgtga gccagtaacc ccaaccgctg ataaaaccag cgaaacggcc
     3901 aaaaccttct tctgcgtaac taaagatccc gccttttaaa tctggacgtt ttttattgat
     3961 attattgatc gacaaggaga gcatcaacat tgctgttcct acgagtaccc aactgaaaat
     4021 agctgggccg ccagccgatc cggagatgtc cgtcataata ccaaatacgc cacctccaat
     4081 cgctgaacca attactaagg cagcaagtgg aattaaacca attccttttt tctgttgctc
     4141 tgtatccatg taagcatcct ccaaaataaa accgctttta tcaaaaagta taacaaacct
     4201 tttttatttt tacttaatta ataaaaactt taatagaaat ataattctac cggctttttt
     4261 ctcattatac aagcaaagcg cctagtccct ttccaaatta caccaccaaa aaacttaaaa
     4321 aagatgctat actaaaagga aagaattgga ggatgatcca tgaacatttt atatatatcg
     4381 atttcaggaa atacgcgtgc ctttgccaaa catctagcag aatatgctga aaaaatgcat
     4441 gcagaagatc ctgtcaatcc tgaagttact ttaaaagaaa tccatgaaaa tagtgatttt
     4501 acgaaagaaa cagaaccatt ttttactttc gttcctactt atttagacgg cggaaatggt
     4561 ttagataacg gtgatacaga aatcttgacc gaaacgatgc gtgaatatct ggaacatgaa
     4621 gacaatcata aactttgtct tggtgtagtc ggtagcggaa ataaaaactt caataatcag
     4681 tattgtctaa cagccaaaca atatgcacaa acatttggct ttcctttctt ggcagattat
     4741 gaattacggg gaacaccatc tgatgtgaca cgaatttatc agattttagc agaaaacaat
     4801 aaataataaa aaagaagaag ctgaaaaata gatttcagtt tcttctttcg tttctattgt
     4861 ttctatcata ttaagctttg acatccatca caggtgcttt tgcttttgct ttacctgttt
     4921 tttccaagac aaagtttttt acacgatcca tattggttac caagacgatc atggatgttt
     4981 ctttgcctgc tgctttgatc gcttctaagt cagcttctgc tacaagcgta tcaggtgtca
     5041 cttgctgccc ttctgttact ttcacatcaa atggcgtacc gcctaagtca actgtgttga
     5101 ttcccatatg aagcaagatt tctaaaccat ttggcgttgt gatcccaata gcgtgtttcg
     5161 ttgggaagac agagctgact accccagtaa ctggagaata gatatgtccg ttttctggtt
     5221 ctacaaagta gccttcaccc atcatctttt gtgcaaaaac tggatcactt gctttatcta
     5281 aagaaacaac tgttccgtca gcaactgatg agaggatagt cacactttca gctgaagttt
     5341 gaggtactac tttttcaggc acttcattta ctgtggctgt ttcagtcgct aattcttctt
     5401 tttctaaacg gtctttagga ataccgaaga agaatgtagc aacgaagcca ccagcataag
     5461 ctgccaataa tccaaggatg tagcctaacc atttaccgtc agagatcaat gggatcaaag
     5521 cggctcctga aggtccaata gcgatagccc cgacatttcc gatcattccg atcactgccc
     5581 cgccgatacc tccaccgata caagcagtaa taaatgggcg tcctagaggt aatgttactc
     5641 cgtaaatcaa tggttcgccg attcctagga tcccgactgg taaagctcct ttgatcattt
     5701 ctgttaattc tttatctttt ttgcagcgaa tccataatgc caatgctgca cccacttgtc
     5761 ctgcaccagc catcgcaaga attggaagca atagcgtacg accagtttca tcaatcattt
     5821 gcacatggat tggagtcaaa atttgatgca gtccgaacat aaccatcggc aagaataatg
     5881 tgcctagaac gaagccggca aatgctccac caacgccaag tacccagttg atcccaccga
     5941 ccatgccatc agaaatgaaa cctgctaaag gcatgatgaa gaaaatttca atcagaccga
     6001 tggcaatcaa tgaaagagtt ggtgtaacga tgatatctac cgcatcaggt actactttat
     6061 gcagtttttt ctcaacgatt gacaatagcc aaacagcgaa gatgacacct aggatcccac
     6121 cttgtccagc tgcaagagct tcaccagtaa ataagttttt cagtggtgct tccggattca
     6181 tccctgtcag catcacaacg gccccgataa ctccaccaag agttggtgtt gcaccaaaaa
     6241 cttgtgcagc attgatacct gtatagataa ctaggtagct aaacatcccg tttttcaaga
     6301 tgttcatcac atcgatatat tgttgccatg ttgctgcatc aagtgttccg gctgtgacta
     6361 agtttgctaa aactgcggca atccctgcca cgatcccagt accgacaaat gcaggaatca
     6421 ttggcacaaa gatattagaa atgtctttta ataccgattt gattttagat ggtttttgtt
     6481 tcgatttttg tgccgctttc atttcttgtg cccgttcgtt tacacggtct tttccagatg
     6541 ctgatgaatt tgctgtagct gtacttacag aagaaagttt ttctcctaat ttcacgcctg
     6601 ccaaatcaac catttgctgt gctactttgt tcactttccc aggtccgatg atgacttgaa
     6661 gctgttcatc ttctactaca ccaagcactc ctggaatcgc ttttaattca gagacattta
     6721 caagatcatc attgatgatc ttcatacgca cacgagtcat gcagtggaca atgctttcta
     6781 cattgcccat gccgcctgcc cctttataaa tttgttttgc cagttcttcc aaagtcagtt
     6841 cgttttttgc catggtcttt tccccctcat aaggtccctt ttacaaatcc gtttgcttca
     6901 gctaattttg cttgagcttc ctctttatca ctatttgtca aaatcatgac gatagccagc
     6961 ttaacatttt gatctgcttc ttcaaagtac ttttcagctg tttcgtaatc agcttctgtc
     7021 gcttgcatga tgattcgttt tgagcgttcg attagttttt catttgttgg tttgacatcg
     7081 accatcaagt tattgaatac tttacctata ccaatcatac tgatagtaga aatcatattc
     7141 aagataagtt tttgtgctgt tcctgacttc aatcgagtag agcctgtcaa aaattctgga
     7201 cctgcatcga cttcgattgg gaaatccgcg tgtttactga tttcggcttg tttattgcaa
     7261 gaaatcgttc ctgtgacagc accgatcgat tttgcgtaat ctaatccacc gatcacatat
     7321 ggtgtacgac cgctagctgc gataccaata actatatcat tttttgtcaa attcagcttg
     7381 attagatctt cttgccctag ctcataagaa tcttcggccc cttcgacagc tacagtcatt
     7441 gcttcttctc caccagcaat tagacctatg accatttccg gttctacacc gaatgtcggt
     7501 acgcattcag cagcatctaa cacacctagt cttccacttg ttccggctcc catataaatc
     7561 agacgtccac cttttttaaa ggactcaatc gtgttagcaa tcactggttc gatacttgtc
     7621 agttcttttt caaccgcagc ggccactttc tgatcttctt tgttcattag ttgaacggct
     7681 tgagaaatac tcatctcatc taatccaaaa gtttcttggt ttctgcgttc cgttgttagg
     7741 ttctctaaat tgattttgct catttttatc ttccttcttt tcttataaat tgatagttca
     7801 taccagcttt gatttggttg atcaatggta gctcttcttt gataacttta gctactacat
     7861 tcactttttc atccgctggc aaatcatatt tggttaattg gatctcaccc atatagcgca
     7921 aatacttttc gttatctaaa gtaatagacc ctttcatacg cgtagctgta tttcttgctg
     7981 ggataggcgg aatctctcga aaacgtgcat ctacgcttcg tatgacatct cttgcatcgt
     8041 cttgccgatt cgtatgcttc cctaatatat attcgtaaaa ttcttcatct acaggttccg
     8101 tatggagcaa gactgtctgt tctttttgga aagaagcaaa ttgctcctga acgttttctg
     8161 acagacctgc atctccgatg taaacaatat ccgtgttact tgctaataga tctagagcgc
     8221 ctgcaagagg atggatccct cgatgttctt ccaaagttgg caatccttga tatagtgggc
     8281 ctctcaactc tgtatctcct ggtacaaaac cttggacaag gagaccttga attttgagcc
     8341 attgattttt tttctgatac cattctttgt ccagccctgt ttcgggacgt ggataataat
     8401 tatgccaagc ttcaatctgt gagaaatcag cttctgcttc tttcaattca tcgatatctt
     8461 taggcgtgat cgtgctagca ttcaaactga ttttcaattg atgtgaccag tcggcaatct
     8521 gctgattgga aatatgataa tccattctta aacctgttac accaattgct ttcaaaggcg
     8581 ttagatcttc taatgaaaaa cccgctcgtt ccaatgcctc tcctgaaata tcgaccatca
     8641 attctagttt attctttttc gcttcgcttc ctagttcgat caatcgcttt tgatatgccg
     8701 aaacatcatc ttctggtata tgcatggaag tgaaaatacc gacaaagcca ttggatgcca
     8761 tttggcggat atactgtttc ttctcttctg acaaagaatc gttcataaat attgaaaagc
     8821 caaacatatt atccctcttt ttctgtatcc gtcttcattt ctatgactag agtatatatc
     8881 taaagaaaca aaatttcaat acttttatta aaataattaa atttcatttc taaaggttga
     8941 gtttatatta tcaaaagaat tgtcataacc taaaaaaggc actgctaagc aaaagcagtg
     9001 ccttgaaata ttttatttaa ataacacaaa aacataatta ctcataagaa accaattctg
     9061 tattatctac catgaatgta aagaacccct cattaggcat cggatgaaaa taagcattga
     9121 tcactcttat caaggcatta tggcaaacta acagatagac attttcttcg tcttcgatgc
     9181 attctttcaa taaaggaacg atccgtgcat acacatctaa gactgactcc ccatttggga
     9241 atcgtacagc gaacgctaaa cgtgcttttt gaaagttctc atctttgctt ggcagtccat
     9301 cataatcccc aaaatccatt tctaccaatc gttcatcaac ggtcagcggc aagctgagac
     9361 gatcagcaac tgcttgtgct gtatctcttg ctcgttgaag aggggaatgg atgattttcg
     9421 tgattggaac aggcaaatct actacctttt ctgctagttt ctgtgcctgc atctgtcctt
     9481 tttcagtcag cggcacatct gcccgtccgc aaactaatcc ttgtgcgttc caagttgttt
     9541 ctccgtgtct cgttacataa agcatgtgat tctctccttc gttggcaaag ttccccttaa
     9601 ccataccttg ttgttcttga gattacaagg gttagattct ctcaagagaa ataatctcag
     9661 tagatacttt atccaggaag gtttgatcat gttccactag taacatggca ggtttcacgt
     9721 tcaagatcag ttgttctaat tgttcttgat tgaagacatc caaataattc aatggttcat
     9781 cccatgtata tagttcagct ggctgtgata aagatttagc caattccact tttttccgtt
     9841 ggcccatact catctgctcg atcttgttat gaaaaacatc tctttccatc ccaagctttc
     9901 ggaggttgtt caaaaatgct tggtagtcta cttggttttt ctctgcaaat tccgccaacg
     9961 ttcctcgatt gtcttcataa ttttggcttg cataactaat gctcagatgt tttggctggt
    10021 atttttctcc tataaccttg ccgttgaatg cccccagaag ataatggata atggatgact
    10081 ttcctgcacc gttaggacct gaaatcgcca cccgctgatg aggctcgatt gtaaaatgaa
    10141 ttggctcgaa taacagattt tcatacccta attgaagatc ttctacgctt aaaagtcgct
    10201 tatggtgaga cgcttggcta ttcatcgtca aagaatcgat atattcgata tcttttaata
    10261 gtttttcttt ctcgctgatc tgggtctcca tccgattcac gattgctttg gatcgtttca
    10321 tcgtccgtgc agcatcagca cccactgctc ctttattcac tcgtctagat tcagtatcga
    10381 tgaatccgac ttgtttcttt gttttatctc cttctcggga acgagaccat tcggcttttt
    10441 cagctgctgt tttctttagc ctactgactt cttttttcaa tttttcattt tgagccattt
    10501 caaattcatc acgaagtttt ttctgttctt catagataga gaaattccct tgataaagtt
    10561 ccagttgact tttttcgatt gctaaaacat ggtccactac ttcatcgata aatccccggt
    10621 catggctgac cacgatgaag ccttgttttt tctttttcaa ataagccgct acttgttttc
    10681 taccagagat atccaaatga ttcgttggtt catcgattaa cgggaaatga gtgtcatcca
    10741 caaataaaag tgccagtagg acttttgtct tctctccccc cgatagtgtg ctgaattctc
    10801 tccataagat ttcaggatct gtttgcatca attggagctc tctttcgatt tcccatatct
    10861 caaaatccgt aatatcattt aacacgtaat aggttaaacg ttctttatct tttgtctgtt
    10921 gcgggaaata ggcaaattct tgctgatgga ttacttgccc ttgataaggt agtttgtttt
    10981 gtagaatatt cagtaaagtt gtctttcctc gaccgtttcg tccgataagt cctagtttcc
    11041 attgtgtgtc aaaatttaga tttgcttgtt caaataataa tgtgccttgg ctgtcgtagc
    11101 cgaatgtcag attttttatt tcgattttag acattttcca tcacctcgta aaaaaagacc
    11161 agtcctattt tcagaactgg ctaaagagga tgcaagggtt ggatacacac aaaaagaccc
    11221 atacatcgaa aaaaccaagc caatcccgaa aatctgcaca ctgcttcctt gtctccacaa
    11281 ggtacagtct gaatgcagct ttcatcaatc gacttaattt ttcaatgcac ggatccctca
    11341 ctttgtccta tatttgaaat tacgatagca taaagaaaat gattttgtca actacttcgg
    11401 gaggatggtg aaaaatctgc taagtgtctg tcctaagatt tttgtttttt ctaatgtttg
    11461 cctgtgttcc attgcttctt ctaaacctat tggacccaaa tgaatactta agacaattgg
    11521 gagaaaatca gaaagtcctt ctagctcttg gtctctactt ccgcaaatag cgattattgg
    11581 ttttcgatat ttttttgcaa gcactgctac accgtatgga acttttccgt ggatcgtttg
    11641 ctgatcgatc cgcccttctc ctgtaatgat gacatctgct tgttcgatct ttttttccaa
    11701 tccagtgatt tggctgacta aatcgaaacc agaaaccatc ttcgctccca acaaaaaaag
    11761 ggctccacca ataccgcctg ctgctccact tcctggaata tcatctaaat ccacctccca
    11821 gaaatctttt atttgctgag caatctttcc tgcttgttta tctaagaaag ctagcgtcgt
    11881 atctattcct cctttttgtc ttccaaattg ccaagcagct ccttgttgac ctgtatatgg
    11941 attggtaaca tctgcagcga taatcaattt tactttagaa acaagaacgt ttcttcgatc
    12001 aaaatgaagt tttttagtag ataataaagg atttccttct gtgtaccctt ctaaagaagc
    12061 acccaaggat tggagtaatc ctagaccacc atcgctacac ccgcttcctc ctaaagtgac
    12121 aataatttgt tctacttctt gaagcagtgc atctttaata agttctccta aggcataact
    12181 ggaagcaagt cggatagttt gatccgttgg tttatcaagt agatctaacc ccaatgcttg
    12241 tgcagattcg atgactgcgg tgttttttcc ttgccaagtt gtcaataaat agctgatttt
    12301 tcgctgacgg aataagagat ccatcccatc aatggtacgc catgttcccc tgagcgcgta
    12361 atagattgct tctgcagtat tttctccgcc atctgcaatc ggcacattga tttttcttcc
    12421 tttacgatct tcccagccat ttagaactgc ctgatttagt tcaaatgaag aagcacttcc
    12481 tttaaatgaa tcaattgccg ccaaaatatc catctgtatc cctcactttc ttcttaagta
    12541 agacactttt tttcattttt ttcaaacaaa acaatgctat tttcttccat ttttctatat
    12601 actaaaaggg aactcattga ataaaggaga gaaaaaacat gaaaatcgca atagctgggg
    12661 ccggagcaat gggcagccga atcggattga tgctacatca aagcggaaat gaggtcctct
    12721 tgatcgatcg ttggcctgct cacattgaag ccattcgtac aaatgggttg attgctgact
    12781 ttaacggtaa agaagtggtc gcaaaactgc caatctattc accagaagaa atcatcgaaa
    12841 gcaacgaaca cgtggacttg atcgtagcat taacaaaagc caatcaatta gatgatatgt
    12901 tttgttcgat ccaatccatt attactgaca atacttatgt tttgtgttta ctaaatggat
    12961 taggtcatga agatgtactg gaaaaatatg tgccaaagaa aaatatctta tttgggatca
    13021 cgatgtggac agctggtcta gctggtcccg gaaaagtcac attgttaggt gatggagaaa
    13081 tcgaactaga gaacttggaa ccagaaggcg aagcatttac aaaaaaagtt gtagaagtct
    13141 ttcaagaagc aaatttaaat ccgatctata gccataacgt tcgttattcc atttggcgaa
    13201 aagcttgtgt aaatggaaca ttgaatggtt tatgcacgat tttggattgt aatattgctg
    13261 aactaggcgc gcaaaaagcg gcagagagca tggttcgaac aatcgtatct gaatttgctt
    13321 ctatcgcagc aaaagaagga atcatactag atcaagaaga agtgtaccaa catattgctt
    13381 ctacttatga tcctgacaac atcgggttgc attacccatc tatgtaccaa gacctgatca
    13441 aaaaccatcg tttgactgaa atcgactaca tcaatggtgc catttggcga aaaggacaaa
    13501 aatatgatat tgctacacca tattgtgcct ttttgaccca attagtccat gcaaaagaag
    13561 gaatccttgg cgcagaataa aaggctctct gatgagaatc agctgaatca gcagctggtt
    13621 ctcttttttt aagcccaata aaagatcaaa aagaaaacac aactctcatg atgccataag
    13681 aattgtgctt gtttgtttca gtacataatc tcttcaaaat gtaggttttt tatttgtttt
    13741 caacagagga gaggtcatat tcgtattgct cataaatagt ggaatcgtta gtgataaatc
    13801 gttttgccca attttctgca tcataaaatt ccaatagctc tgataggatt ggcttaaatg
    13861 gtgtatgcag aaattccggt aattcatcta aatcacgttc tcgaagcaaa aaaatatttt
    13921 caggacgata aaaatgataa tgagcaatcg cttgattatc cgtcactagt ttcttttgaa
    13981 aatacatgga ttcaaatgtc cgcaaagtca ctccttgctg accctcccgc aacagttcca
    14041 gaatcccgcg cgattcccct gtttttttca ggtactcttc ataagtaaga tatccaggtt
    14101 gttcattccc tcgatgtgga agaatgaaat agttggtcgt aacatctctt tttataaatt
    14161 cctgcttata gctttctgct cgttcttttc tcccattatt cgttgcacca aaaaatagat
    14221 ccgtctttgg ttcgctagaa gaaaaattca tatgtttcga ataaaatgaa ctattatgtt
    14281 tcagcccaag ttcttttgct tccaaaaaat caaaatgata aatctcatcg attgccggtt
    14341 catcttgtgc ctgcttcagc atcgcctcgt gttctgcttt gaagtgattc caaaaaaata
    14401 acacaatttt tgcattggta aatgggcgca cgcgtcgagc catctccata tcaaatccat
    14461 aatctaaaaa aacgatcagc tgataatttg ccaactgttg tctagctgat ttaatgaatt
    14521 ccgactgtag taaatctttt ccggaccaaa catctaaaga gcggatggaa ggcaaaaaat
    14581 aaagtgattt attttttgca actagcagta cgtcattttt gttcatcttt tccgcctcac
    14641 tttctctgtc actttttcct atgatagcct gtttaaatag taaaaagcca gtaaaacgtt
    14701 tcctatattt gtatgaaaat ttaacatttg tatgaaaata tgatgaaata aatcattctt
    14761 ctattaaaat tcgcctaaaa gttttctgaa tagttgtaat tgtctgaaaa tttgttatca
    14821 ttagtcattg ttaaatattg ctatttattc ttaatataaa ttttgattgt gaatttaaaa
    14881 gaaagaggtc atttatggaa gataaaaaat tgaaaaaaca acttagctcc agacatatca
    14941 ccatgttagc tttaggtgga gcaatcggtg caggtctatt taaaggaagt ggcgaagcga
    15001 ttgggatcgc cggcccttct gtattgattg cttttttgat tggtgggctg attttatata
    15061 tcgtgatgaa aggtctggga aaaatcgttt taagcggtgg cgacacgcat cacggattat
    15121 ctggtttgat acgcccttat ctaggtgctc attctgctga ttttactgat tgggtctact
    15181 ggtctatgtg gattatcaat atcatcgctg aagctgttgc agctgcttcc tttttgcagt
    15241 tgtggttccc gcacattcca gcctgggtat ttgtttttat gttggctgtt ttaactacga
    15301 tcatcaatct ttattcggta cggttattcg cagaaacaga atattggctg gcttttgcta
    15361 aaatcagtgt cattatctta ctgatcattt ttgctactta tcttgtcggt cagcaaatgt
    15421 tgggcacagg cgttttccct acccttcagc aattgactga ccatggtggg tttactcctc
    15481 atggtatgaa gggaatcatc agttctttgc ttgtagttat ctattcttac ggcggttctg
    15541 aactgattgc tatcacggta agcgaagcag atgatcctaa acgtgcgatt cctaaagcaa
    15601 tcaaaggtgt catgggaaga atcatttcct tttacatcat tcctttgttt ttgcttttga
    15661 ttctttttcc ttggaatact ttagcaggca cgaatgtcag tccttttgtg atggtatttg
    15721 aaaaaatgaa tatcccattt gcagcggata tcgtcaattt tgtgattgtc cttgctttgt
    15781 tctcatctat caattcgggt gtgtatgcat cttcaagaat tttgttcttc cgtttgaagg
    15841 atcgaaaagg ttcctctaga aaactagctg ttttaaacaa gcatcaagta ccgcaacgtg
    15901 ctgttttatt ttgtaccagt gttctttatc ttggtgtagc tctttcttat tttgtcggtg
    15961 acaaattatt tggctatctg gcaggttccc tttcgtatac agtattattg atctggatca
    16021 ttatcagtgc ggcatccttt gtactggcac taagaaaagg aacattatgg gataaaggaa
    16081 tcagcttttt tgcattagct gtcttaggat tgattttcct tggtatcctg ttcacgaact
    16141 ccattggggt aactgtattg actggcctgc tttacctgtt catttatttc agttatcaaa
    16201 aaaagaatga tgcgttcgta ttgacgaatg aatgaaatcg atagaaaatt ttattttatt
    16261 tatgtggaat agatggagct attgaagaaa ggagttgtga caaaagtctt gttgcaactc
    16321 ctttttccga ataaacagtc tcatgacctc ttggtaaacg gtgttcaaaa accctctgtg
    16381 caaaataatt gattgttctc catgctcatg acatgataga agaaaggaat gaaaaaaagg
    16441 agtttgtttt aaatgaaaaa gtattggaag tttttgttga tgatcggtgt ttcaacggta
    16501 gttatgtttg gtatgatgta cttgaatgtc tatgcgctcg atcatatctt cttcagtcgt
    16561 acacgagtat tcatggcgtt gatgatgggt gcagtcatgg cagtcatcat gctgttgttc
    16621 atgtggaaaa tgtatgaaaa caaaaagata aatgttatga tcttagccgc tagtcttctt
    16681 gtttttgccg gttccttgtt tatggtacga agccaaacta ctgtcaacga cacagcttgg
    16741 atgaaggcca tgattcctca tcattctatc gctatcctgg caagtaaacg agctgattta
    16801 aaagatcctg aagtaaaaaa attagcggaa gaaatcattc aggcacaaga agaagagatc
    16861 gacaaaatga aaaaaatgat caaagaaatg gaatgaccat tatccgtcca aataaaaaaa
    16921 gaggatgttc cagaagttat cagcttcaag aaataagaag aagctacttc tggaacgccg
    16981 tgaataaggg gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa
    17041 tagcttctcc tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac
    17101 cgtttattaa gaggttgtaa aatcagcgtt ctgacctgag tattagagag acaaatggaa
    17161 aaatagttcc tcatattttg ccattttttg agctaatacc gagggtcagc tgattgaaca
    17221 ccgtttatcg agaggttgtg aaaaagtcgc ttagtttcgc gtattaagaa aaattttgtg
    17281 aaatggcttt ccacattttt gtataaattt ggcttaatac cgagaaactg gcttttgaat
    17341 accgtttatt cgtaaaaggg attgtgacaa aagtcttgtc acaatccctt tttatgtttt
    17401 tattgttcta attgcgctgt cttgcttact gcttcttgcg gtttcacaaa tttttttgag
    17461 attccccaac ctgtgaaggc actgaccatc gaaaacacag gagaaagcaa actgaaaaat
    17521 acgaatggca agtaagtgag tgtaggaata ccaaatgtac ttgctacgaa acttccggca
    17581 attccccaag gcactaagta gttgattact gttccaccat cttctagcgt tctacctaat
    17641 acagttggat caaatcctgc tttttcataa gtttctttaa atgcattacc aggcagaata
    17701 acagatagga attgttcacc aataaaaata tttactccga tacttgtcat caatgttgta
    17761 aaaatcaaat ttggtgtgtt cgtcatcttt cttgatactc gttccatcac ggttgagatc
    17821 aagccaaatt cgatcaacaa tccacctaat gacaaagtta gaataatcaa tgacacagta
    17881 ggcatcatac tttcgattcc tccgcggcta agcagtgaat cgatttgttg gtttccagta
    17941 tttgaaacaa accctgattc gatgacccca gccaacttcg ttaaggaagt ttgtgggttt
    18001 tgaataaaaa tcattcctac tgctacagcg atattcaaca aaatcgttaa aattgccggc
    18061 acctttttcc atgcacacag taacattaaa aataaaggaa tcagtgacca gattgaaata
    18121 gtaaagtttg cttctagaac atcagtcact tcacgaatag atgaaagact tgcggcttta
    18181 cttgtgtgtc ctaaaatcat gaataaaaag aaagaaacaa caaatgccgg gacagttgac
    18241 cacatcatat gcttgatgtg tttgaacaaa tcggcatcaa caatagctgc tgctagattt
    18301 gttgattcgg ataatggaga catcttatct ccaaaaacgg cacctgaaac aatagctcca
    18361 acaaccagcg ctggatttaa gcctagtgtt gtcccaatac cgaaaaatgc aatcccaatc
    18421 gttgacataa cagtaaaggc actccctaca gcgctaccta cgattgcaca cacaacaaat
    18481 acagaaggga caaaccactg gacactgatc aatttgaacc caatgaccat tagagttgga
    18541 atgatccctg cttgtatcca tacagcaatc aatgaaccga ctaaaataaa aataaagatt
    18601 gggatgattc ctggtttgat gccattgatg attccttcgt gcagccaatc tgtcgggtat
    18661 ctttttatca ctgcatacaa catgaccatt ccgatcgctg ctaagatcgt gatattaggt
    18721 gagaccttta atccgacaac gccaatcgca atgcctaaaa caataaccat taatacaagt
    18781 gttgcttcta aaaaacttgg tgttcctttt tttcccatga taatctctcc ttttttagtt
    18841 gttcttatgt tctaaaaaag ttaagatatc ggattactcc gccgcaattc atccgcgatt
    18901 cctcctttat aaaaataaaa agacctgttt taaactaagg acgaatgact ccgcggtacc
    18961 accttaatta aaaacagatc tgtttttcac tttcaaactt ttattcaaat gtatggactt
    19021 tccatgtaat tcgtcaatta ggcttgatcg gttcacagcg accaccgact ttctgaacaa
    19081 aacacctaac cgctactgcg tgaaaagttg acttgtacga agtttacctt ccataagatc
    19141 atttgtcaat gaaaaagaaa atattttttc atttttctga aaattatttt tataactttc
    19201 acacacaagt ttatttttta ctagaaagta gcgccctctt gtttttttct tgctactatt
    19261 tcttgatgtt cttgcttgat tctttctaat agctttggct ctttcaacag atcaagagct
    19321 gtattggcga gtagttctgc tgcaatcgca atagaagcaa ggcctttgtc acttttagca
    19381 gcagctttga attcttctgt gtgtccggca atatatgtct cagagattgc taccgtaggc
    19441 tggattgttg gtatgacttg gctgacattt cctacatcag aagaaccgag acttgttctt
    19501 tgttccgttt ctatttcttc atctggaaca cctgcttctt ttgcatgctg gaagaataag
    19561 tcatcaaaag aaggagtaac gatgacatca tcaactgcat tttggaacaa tccaaactca
    19621 aaagtcgtgc ccgtacttat cgcagcacct cgtacgatat tttccacttt ttcatatact
    19681 ttatctaatg tttgccgatt tcctgcacgt aaatagaaac gtccagcagc gtaatctgga
    19741 atgacgttgg cagctactcc tccgtctgta atgatcccat ggatattgac atcttttggc
    19801 aattgcaagc gtagagcgtt gattccatta aacacttgga tcaatgcttc caaagcattt
    19861 actccttttt caggtgctgc tgctgcatgg gaagcgacac cgtaaaattt gatgtcgact
    19921 ggatcattcg ctaaagattc tgtcgttttc ccataacgaa aagctggatg gacgcataac
    19981 gctacatcga catcctcaaa aaaaccttct cgaacaaagc tgcctttagc tgatccgttc
    20041 tcgccccctt cttcccctgg ggtgccatat acacggattt ctccaccagt ttcatcaatg
    20101 aattgcttca ctatgctggc ggctaatacg gagtaagtac caaacaaatt atgcccgcat
    20161 gcatgaccaa tacctggtaa agcatcgaat tctgccaaaa aggcaattgt gggaccgggt
    20221 ttattggaaa tataacgtgc atcaaaggct gttcggtgtc cagctacttc tttttctacc
    20281 caaaaccttt ctttttctaa ttgtttaatc aacgctgctg aggaataaaa ctcatagtta
    20341 cttacttcag gatgttcgtg gatatctaga gcaagtgctt gatattctgg taaacgatat
    20401 tggattagat ccttcaattg gtttgttgag attgttgttg tcataaaaaa ttcctcctat
    20461 gctagtcatt tttcttattt tctcccgaat gtttcccatg caggcacgct tgatcctttt
    20521 gatgttttct cgattacttt gactgtgtct tctgtttgat aagcgtctac tattttttga
    20581 tacgttttat tgttttcatc ttcttttctt gcaacgatga tattcacata aggacgtgca
    20641 tggtcatcca ctggttctaa gaagatggca tcagaagcag gattaaatcc agcatctaca
    20701 gctacaccgc tattgatcac tgaaatgtct acatctgaca aagcacgtgc tgtttgggaa
    20761 gcatctaatt cagaaatgtc tagatttttt ctattctcgg taatatcaga aacagtgggc
    20821 gcttgtcctt ttgccttatc cactttgatc aatccagcag tttgcaataa cagaagagct
    20881 ctgccgccat ttgtaacatc attagggatt gctacttttg ctccgtcttt gatatcagct
    20941 acatccttca aagtgttaga ataaattccc agcggtgcat tgacagtatt tccgatcgat
    21001 actaaatcag ttccgtgttc tttattgtaa ttgtctaaaa agaattgatg ttggaaagaa
    21061 ttcaaatcaa tcgatccatc tgctaaagcc acatttggtt gattgtaatc tgtaaatttc
    21121 acgtattcca aattaatgtt ctcctttttc aaacggtctt tcacgttgtc ccatacatct
    21181 gtatcttctc caataatccc tagttttacg atagtttctt ttttgtcagt tgtatctgct
    21241 tttccttggc tacaccctgc caaccaaata attgctacaa atgtaatgac tacaaaacga
    21301 ataatttttt tcattttttc tcctccactt tcaatgtgta atttttttaa tcagttgatt
    21361 actgataaat tgacttaaaa aaactaagat tagaatcaat aatgtagcca caatcgttac
    21421 atctgtttgg aatcgattat accctctcga tatagcaaga ttccctaatc cgcctgcacc
    21481 tactgctcca gccatggtag tcagtccgat cacgttgatg atagtcaacg ccgagacccg
    21541 aatgatacca ggcaaacctt ctaacaaata cacacgtaaa atgataccga ttggactggt
    21601 tcccatcgct tctgccgctt cgatcacccc aggatcaact tctagcagtg cgttctcgat
    21661 ttgacgagca aaaaacggaa caactccaaa aatcaatggc actaaagctg ctttcgcacc
    21721 aatcgtcgtt ccaactaaga aacgagtagt caatgctaaa agagaaagca agataatgaa
    21781 agggatggaa cgaatgatat tgatcagctt atcaagtatt tcaaatagca gacggttagc
    21841 tagtaatcca ttagggcgtg tcactactaa cgtcacacct aagatgattc caatcatccc
    21901 gccaatgaat gctgtccaaa aagacatata tagtgtttgc ttcgtcgctt cgacaaattc
    21961 atccggaatc aaataaacat tgggcaaata tgttttaaag aaatcagtca ttttatcttc
    22021 ctccttcgat cactttgata cgactatcta aatcgttttt ttgtaaaata tttattttta
    22081 caccagattt gatcaaataa tccaatgctt ttttccgctg tttggtttct ccagctaaag
    22141 taacgatcaa actccctaac ggcgtttctt gtaataactc tacattgcca tataaaatat
    22201 tcgctgttac ttgatatttg ctgtacagat gagcgattag aggttcgttc gtctgatttc
    22261 caatataact taattccacc agccatttat tggcgatctg atcggcaaaa gcagaatggg
    22321 caatgatcgt ttctaatgct tggtcaagat gagtagctgt tcgaataaaa tctttggtca
    22381 attcttcttc aggattgctg aagatctgga tgctgctacc tttttcaacg attcttccat
    22441 cttccataac cgctaccttg ttgcagattt ctttgacaac ttgcatctca tgagtgatca
    22501 ggacgattgt taaacctaac tggcgattca atttttttaa caatgcaagg atctgaaggg
    22561 tcgttttcgg atcaagtgca ctggttgctt catcacataa taatacctta ggttcattcg
    22621 ccaaagctcg tgcgattgct actcgttgtt tttgtccccc cgacagttgt ttaggataag
    22681 cagatgcttt ttcttccaaa ccgacaagtt ccagtagttc attcactttt tgacgacgtt
    22741 cctgtttcga ttttccagaa tactttaaag aaaaatcaac gttgtcaaaa atagttcggc
    22801 tttccattag attgaaatgc tgaaagatca taccgatggc ctttctttct tttcgcaatt
    22861 ctttgggaga gagctgactc agattcgtct gattgacaat gacttctcct gctgttggtt
    22921 tctgcagcaa attcatcaca cgaactaacg tacttttccc tgcacctgag taaccgacga
    22981 ttccataaac atcgcctttt tcaatcgtta aatctacaga atctactgcc tgtatctctt
    23041 tttctttttg tttgaaacat acagaaacat ctcgcaattc aatcattaaa attcctcctt
    23101 atctaaaaaa agcgtcctca agaaaatgaa aatgtcattt tcttgaggac gcttttttgc
    23161 gtgttaccac ctcatgttca agctgtgttc acacacaact cctcttcaag tacgatcata
    23221 ctctagcaag atatcggtcg cagccgtcat cgccttacat ctatgctcgg gatgaattgc
    23281 tcgatggcca ttttccaata gtcgttcctt gcttcttctc agctaccgaa gctctctgtc
    23341 aaaggttctt ctatcgtact taccatttca atgcaaataa tattcaaaaa aaaagtcctt
    23401 ttactaacat aaactatgtc agtaaaagga cgacgtatcg cggtaccacc ttttttcgga
    23461 agtttccttc cctcaagccc aacatctcaa aaagagagat tggcgttcgt tttaacggtc
    23521 gaacagttcc gaatttgcct acttatcgac aaattattct ccaaggccat tttcagcttt
    23581 tcttacttga ctcttctcac cagccagagc ctctctgcaa agtttccaaa cttactttcc
    23641 ttttcaacga aatcgatatt ttgttgttgg gattaatcta catgaggaaa actgaaaagt
    23701 caagtacgaa attcaaatta ttttttctat atttattttt ctgttttttt atttaacatt
    23761 tcaataacag ttcgaagatc ttttccttcc gcaagaagtt tcaatttttc cttttcttcg
    23821 acggtataat ttcggacaaa actggaatca ggtatcaaaa caacgcctaa tcctgctcgt
    23881 gaagcagctg ttgctcctac taaagaatct tccactgcaa aggctgaact agcttctaat
    23941 cctgttcgtt ccaaagctgt cagataagga atcggtgaag gcttgttctc cgacacttcg
    24001 tctccgaatg taaacgtgtc caagtaatca gctaatttaa agtgatccaa gatatctgtt
    24061 gctcttttcg taacagtggt cgtagcaatg cctagtttca tatgacgttc ttttaagtct
    24121 gccaatattt cttttgcata tggttttaag tggatggctc cgcttgtcag ctgttgataa
    24181 aaatattctt cacgcttcgc tcggacttcc tgtacttttt cagggctacc tgctgctttc
    24241 actaaaatat caaaactttg tttccagttt tttccgcccc aagcgtcaac gatttctttt
    24301 gggatatgga tatcaaattg ctgaaatccc caaagccagc catcacgata cgttttttct
    24361 gtgtcaacta acaaaccatc taaatcaaat attgcacctt tcatctatac attaatcctt
    24421 tccaaaacaa tacacatagt ttagcacgac tggtccaaaa agaacagaag caaagaacca
    24481 gccttctcgt ttataagagt tcttggaatc gacggatata gattttcttc acagctgtca
    24541 caagcgccag ataagcgatg actgtagcaa ataaccataa ccagtaattg ccaggaagtg
    24601 gcatcaagcc taattcagca ccaaaacttg taaaaggaag gacagaaccg acaataattc
    24661 ctaatgtagt gataacaaac atggcaaatg ttgcgttgct ttggataaat ggtactttcg
    24721 gtgtacgcag tgcatggagc actaaggttt gtgtccatag tgattcgaca aaccatcctg
    24781 catggaataa tgcgatgaaa atcactcgct gtgaactatc caatgtatgg aaacttccgc
    24841 ccactacagc aggacaaata acaaaataca tcaacaagta agtagtaata tcaaatatcg
    24901 aacttgttgg accaaagtaa accatgaatt ccccaatact agatgcattc catttttttg
    24961 gctcgtccaa atattcttta tccatccgat cccatggcaa ggaaatgcag gaaacatcat
    25021 agatcagatt caaaaacaaa agttgtaaag gcagcattgg taaaaatggc aggaacgtac
    25081 ttgcaatcag cacggaaaac atattgccaa aattagaact tgctgtagcc ttgatatatt
    25141 tcatgatatt cccaaaagtt tctcgtccag aaagaaggcc tctttccaaa atcgtcaaat
    25201 ctttttctaa aaggatcacg tctgcagatt ctttcgcaat atccacagct gtatctacag
    25261 aaataccgat atcagccact ttcattgcag gagcgtcatt gataccatct cctaaaaatc
    25321 cgacagtatg accattttta cgtaaagctg tcgtcaaacg tgctttttgc tgaggattca
    25381 attttacgaa tacttcatgg tcttcagcta cttgtgctaa ttcatgatca ctcatttccg
    25441 agattttctc accggtaacc aattcattga tctctagacc tacttgacgg cacactgaac
    25501 gtgtaactaa ttcgttgtcc ccagtcagaa cttttacagc tacaccatgt tctttcagag
    25561 ctttcaacgc ttgtttcgtt gtttcttttg gtggatcaag gaaagcaaga taaccaatca
    25621 aaaccatgtc tgactcatct ttgactgaaa attctccaac gacgcttgga ttggtctttt
    25681 gtgcgacacc aatcactcgt aagccatctt cattaagtga ctgtactttt gcaagtacgg
    25741 cttcttttcg ttcttttgtt aatggtgtaa cagtaccgcc aagatcaata aatttagaaa
    25801 tgttcagcat ttcttcaatc gcaccttttg tgatcatttg tgttttacca gctggatcag
    25861 caaccacaac actcatacga cgacgttcaa aatcaaaagg aatttcatcc actttttgat
    25921 aattgatctt atctgtatct aaagtttctg ttgcttcatc aatgatagcc acatctaaca
    25981 aatttttcag ccctgtttga tagtagctat ttagatacgc atggcgcaaa acacgatcat
    26041 cttcatttcc ttcacaatcc atatgatatt caagaatgat tttatcttgt gtcaatgtcc
    26101 ccgttttatc cgtacataac acatcgattg caccaaagtt ctggatggca ttcaaatttt
    26161 tgatcactgt tccttttttg gccatcacac ttgctccttt gaccaaattc gtcgtaacga
    26221 tcattggaag catttcaggt gttagaccaa ctgctacaga tagtccaaaa agaaaagctt
    26281 ctagccaatc cccttttgta agcccattga tgacgataac tgctggagcc atcaatgaca
    26341 taaatttgat cagtagcatg gatgttttat ggatgcctaa ttcaaagctt gattgaattg
    26401 gtttttcaga tagcgtttct gctacatgac caaatagtgt ttcatttcca acagaaacaa
    26461 tgattccttc cgcacttcca ctgatgacat tacttcccat aaagacaaga ttttcgtaac
    26521 ttgtttcgct ttgctgatcg tcttcacata ctttcgcatg cttttctact ggatagcttt
    26581 cccctgtcaa tgctgcttgg gaaatgaata aatcctttgc ggacaataaa cgcatatccg
    26641 ctggtatcat atcccctgct gaaagccgaa caagatctcc acagacgatt tcttccatag
    26701 gaatctctgt gtactttcca ttacgtttta cagctgccgt tactttcaca agtgatttca
    26761 gtttttcagc cgcttgattg gaacgtacgg actgaatcaa cgtcattgtc ccgctgacga
    26821 taaccatagt gaagataatg gctacaccga aaagatcttt atctccagga gctgctaata
    26881 catattccgt gatgaatgaa ataattccta atgcgatcaa cactaatgta aatggcgtga
    26941 tgtatgcttt caatatttct acaatgaatg gtgttttttt gccatatgaa atcgcatttt
    27001 caccgtaatt ttctcttgaa cgttcgattt gttcttctgt caatccattt gctgatgcat
    27061 ggaatagttc aaataattct tgtttcgttt ttccagcaaa agctgcatag attttttgtg
    27121 tatctttctt tttttccatc tcaatctctc ctttgtgtcc aaaagacagc tgttctcgct
    27181 gcttttggtc tttagctatt catcggatcg atagagaaaa aactgaaagg ggctgagaac
    27241 agatagataa tagccctggc ctttcctcta gatccttgtt tttcgaatga ctgtcatcca
    27301 tttgttctca tctcctttac taagtaattt taattcatga cttccaatca tttttcgaat
    27361 agttattttt ccaattagac cacctccttt ttatttttca ccgatgggga tttgcggcaa
    27421 caaaaaaacc tctcgccaaa tactcagcga aaggtttgaa aaagcatatt aaaaaaagct
    27481 tctcagatct catcgttgag ttttgacact gtacaacgta aaaagcagat acctgctttt
    27541 agctacctta tgaaaagcct tatctcgaca attcctgttc tacccattgg cgtctctcga
    27601 cgtttttggg cagtagccta tgtttgtata ggagcctcac ctaacaaatc ttattcggtt
    27661 ttccttcgtt aatataacaa ctaaaaaaga ggatgtcaaa tcaattttcc atgtttttca
    27721 tacttttttt aaaatacaca cgttatattc ctgtctcacg cggttttatt tgtctcattt
    27781 tccacctccc gctataatag aaatatagta ggaaacgagg tgctgttatg gaaagaacac
    27841 ttgttattat caagccagac ggcgtgagac gccatttagt cggaagcatc atccaacgtt
    27901 ttgaagcaaa gggactggcc attgctgaaa tgaagtttga aactatgact cctgaattag
    27961 caaaagaaca ttatcagcac ttgactgagc gcagtttttt tgatgaactg atcgattaca
    28021 tgacttccgg tcctgtcgtt tatcttgtgc tggtcggcga ggaagtgatc gatatcgtcc
    28081 gtaagatggt tggagcaaca aaagctgccg atgctgttcc aggtacgatc cgaggagact
    28141 acgcgctgcc ggggactgaa aacatcattc acgcttctga ttcccgtgat gctgcggtaa
    28201 aagagatcgc ccgctttttc ccgccattcg atataaacaa accgtctgaa aaagcggcga
    28261 agtgatacaa attctaaact gctggtctag ttgctgggtt cagcaatggc cagcagtttt
    28321 ttctctaagg acctccgttg attctttcct aacatatatt cgagcactgt gaagaattct
    28381 tggtagtctt tcgtcttttc ttcccctaaa gcagcagaaa tcaatctttg ataataatct
    28441 gccatcaatg tttcatagat cactgtactt ctttctttat gtgctaagct ccgtttcata
    28501 tcttcattca cactacgtgc ctttttcaac cgaccatttt ctatataaaa cgaagtcagg
    28561 ttcattaaaa aagtaaagag atactgctca tgattgttca actgtgctaa tcgtcgcatt
    28621 ctttttttga ttttcaaata attgttctca atgaaccgat cactgaatat ccaaggaaaa
    28681 tcagctagaa tagatagttc aaattgacca tagtctggta tctgcatcaa gtattcttca
    28741 atgattcggc attcataacg taaaaattca aattctgtct cagatacttc tgttttttcg
    28801 accatgtgaa gattcaaaac caaataatac agatcttctg ttttcttaaa atgcctacgg
    28861 ttattgctga tctctttata aggatcaaag ctgtcttctt gtacccgatc tagcattcgt
    28921 ctttttttct ttaactttat tggttcatcc agctggtttc gcatccattc atattctgca
    28981 agtgtcatgt tcattcgctc taaaaatgat ctcaatgtta caaatgacat ttttttcact
    29041 gaatttgtct caatcccgac tagagaagtc ttaaaacaga ttccttccgc taattgggac
    29101 tgtgtcaact tcttgttgac tcgaagtttc ttgatcaatt caccatcata cataatagtt
    29161 ctccttttta atttaaattt ttccacattc aataaataga tacgttaaaa aggaaaaata
    29221 cacgaaaaaa ataaaaaaat gtttttttca taaaaaatac caaccttcaa gcattagaat
    29281 gttgtctaac tactgaaggt tggtttgatt gtttattgat tatttttttg ctgttcaacg
    29341 tctgttcttg ttactggata taagttggtt gttgttttat taccattttt tgaaaagaca
    29401 cttgtcgaat gttcgccttt ttgcttttcg attgcttcat tacgttccgc ttcattttta
    29461 tagtcatatt ttttcggatc aatcgtctca aatccgtttg gcacataaaa ccgcaagaga
    29521 ttttcctgat tcagcttatc tgaaagactt aacgcagtct tgactttttc ctgatctttg
    29581 gagatttcct catcgattcc tgctgctttc gtatcgatga tttctcctgt ctgattattg
    29641 taagcttttc ctcctaggac ggtgtatttg ggtgtcacaa agttcccatt tcgaaaagca
    29701 actacttgat catgctgaga agataataag tctgtaccaa aatgaagata atctttatca
    29761 tcgattccca atagatgtag taatgtcggc aaaacatcga tttctccacc gtattcatga
    29821 ttgactgtcc ctttagtata accaggcata tggatcatca atggcactcg ttgcatctgt
    29881 gcgttgtcaa attcatccca tgtatctgga tctttaccaa gagcgcttgc taaatcttta
    29941 ttatctgtat tcgagatccc aaaatgatcc ccgtaaatca caaagattga attttggtaa
    30001 ataccagatt ttttcaaata cgtaaaaaat tgttccaatg attgatccag ataatgtgcc
    30061 gttcgaacat aattatctac tgtgctattg ccagtattca aagatggaaa gtcgaaattc
    30121 ttgtcatccg tataataagg cgtgtggttg gttacggaaa gaaatttcgt gtaaaacggc
    30181 tgttgtagat gctcaagata ttgggcagat tctctgaata aatctttatc taatatccca
    30241 taacctaacg tttcgtcgga ttcatcaaaa taagatcgat caaagaaatt gtcataacct
    30301 aagtttttat atacatgatc tctattccaa aaactagcta cattcccatg gaaaacagcg
    30361 cttgtatagc cttgcttttg tccaaggatc gctggtgcgg cttgaaagac attgtctgac
    30421 ccaagttctg tgaataatga gccttgaggt aaaccaaatg tgccagtttc caacatattt
    30481 tcagcatcac ttgtctttcc ctgtcctact tcatgaaaga aattgtcaaa gctgatcgtt
    30541 gcttgattct ggaaaatact atttaaaaac ggtgtgactt cttgtccgtc taccttcata
    30601 ttaatcaaaa actgctggaa actttctaaa tggagaacga tcacattttt ccctttagcg
    30661 atcccaaatg tttcgggatt tggctctgca taatgtttct ttgtataatc taaaacttca
    30721 tcaatcccat tactgcttgc atgcgcgcga acactgctag tcattcctgt tttgattccg
    30781 tcataaatag tatacgcatc gattcctaga tatttgacaa tatatgaacg gtcaaatgtt
    30841 cgctgcagca attgtggacg gttggcttcg ctcagcgcta gatttcctga aaaaataagc
    30901 cctgaaagac aggtaacagc gatagccatc ggtttgccga cagggttgct tttgataggt
    30961 attttcttga ccttcaacca aaccagtagc ccaatgaaca cagcgatatc cagccagtag
    31021 atgacatcat ggggcttcat caaagaaaag gagcttcctg acaatccttg cgacactttc
    31081 gaaaagccta atacagattt gactgtaatg aaatctgtga attcccgata aaaaataata
    31141 ttcaagtaca acaaaagcgt atttaaaata tcaatgatca aaagaatagc taacgctggc
    31201 tttggctttt taatatacaa agaaaggcca aaaaacaata aggtagtcgc aattgggttg
    31261 atccacaaga taaagtactg gatcgtacct tccacaccta atgaaaaatc tgcatagtag
    31321 gcaatgatcg tcttcagcca gaaaaagaaa acagctgtca aaacgattgc taaacgattt
    31381 tggcacaatt ttttaagttg tgtcacgtat atcacttctc tctattcaca ttttttctta
    31441 ttttgctcct gaaaaatgaa aatttcctaa aaaagttgtt atcttaagat ttttttattc
    31501 tttctaaaga ttattccgtc cacttttcac agcataaaac cgctgcgatg taagcgatta
    31561 aactaatgaa gagataaaag tcttgtggtg accgcttcac tccacggtat tcaaaagcca
    31621 gtttctcggt attcgtacaa aaaaagaggc tgtgacaaaa ttcttgtcgc agctccttat
    31681 ttcttgatgc aggacagctt tttcacaact tcttccttaa acggtgttct cctgccaact
    31741 cctcggccac aagtcacaat atttataaaa catgagaagc tgttttttga aattgttcct
    31801 tgtggctcag agttaaacgg caggctcaag acctcttgat acacggtgtt caatcagctg
    31861 accctcggta ttagattatg tcaggacgct aattttacaa cctcttggta aacggtgttc
    31921 aaaagcttgc atctgcggta ataagcccaa ccaaacgaaa aatataagga gctatttttt
    31981 gaaattgctc cttgtggctc agagttaaac ggcaggctca agacctcttg atacacggtg
    32041 ttcaatcagc tgaccttcgg tattagctca aaaaacggca aaatatgagg aactattttg
    32101 ccgtttgttt ctctaatact caggtcaaaa cgctgatttc acaacctctg tttttcattg
    32161 tccataggat tgatattgtc cttgtgatga ctcattcgta ataattgagg cttgattttc
    32221 ttcacttccc gttatcgttt gtccactgcc agaatctgaa ggacttgttc ctgtcgactc
    32281 gtttttttga gaagagacag ttgttttctt gacttgttca tttgtctttt tccattccgc
    32341 taaacgatcg gcgaccactt ttttgtctac tttttcagaa taagcggtga tcacttttcc
    32401 atttttcaaa cgggctactt tgtcgccatc atgagtcaaa agcaaaacgg tcaaatgctt
    32461 gtctttaaat tgatattgtc tgagagaaat cgcactaagt acgtcatcga tattaataaa
    32521 ttgattttct tcttttcctt ttggcaaata aatgtccaat tcgccttttt cgtaattggc
    32581 agttatttta tactccgccc accaataagt tgagaattct tttttgaaat tatctactga
    32641 ttctttgctt gctacgattt tttctgtttc tttctgagca agatctgctg tcatttttcc
    32701 tgaaaatgct gcggataaaa taagcagtaa gaaaaaaccg aataaccaaa agagaagaaa
    32761 cggtcttttt ttcctcatgc tttcctccac tcctatttaa ttttgactat tctattatat
    32821 acaaaaaatg aaatagaaag acaaaaaagt tgaaaaagat cgtaaataat tgaacttctt
    32881 tttcacaaaa tggtaagaat ggagaatttc acgcatttgc tctcaactat tctttcttaa
    32941 gcctcaaatc cgtttttatc tgatacgtct ttgaaccaat gacccgattt tttgattgtt
    33001 ctttttccat cttgtgctaa gtctactgaa ataaagccat atcgattctt atatgcattg
    33061 gtccacgacc agttatccat acatgtccac atatgatagc ctaaacaatt ggcaccttct
    33121 tgaatggctt gatggacata tttcagatga gattggacaa attcgatccg ataatcatcg
    33181 tggatcatgc catcttcttt gataaatcgt gcttcgtttt ctacacccat accgttttca
    33241 gaaataaagc agtcgatatt tccataatga tctcgtacat tgatcaaaat atcatagatt
    33301 ccttgttcat agatctccca tccgcgataa ggattcattt tacgaccagg catttcataa
    33361 ttgtcgaaat aatcctcagg cattggaccg tttttagtat cgattggtgt ttcttttgct
    33421 tttacccggc gtggctggta ataattgata cctaaaagat ctactgtatt ttctttgata
    33481 accgtcaaat cctctgcatg gatcacaggc atgagatcaa gttcttttac tatctcaatc
    33541 aattcacttg gaaactcgcc ttttacagct ggatcaagga atgaacgatt gaagaacgca
    33601 tctgctattt gcgctgcttt aacatcttca gggtttgatt cgtctcttgg atagcttggt
    33661 gtcagattca agatgatacc aataacacca ccttgctcca tttcatggta agatttgatg
    33721 gctaacgctg aagccaacgc ttcatgatag ccaacttgga tcgctttttt catatctgac
    33781 tcttctggat aatgccatcg atataaataa cctgcttcga ctggaacgat tggttcatta
    33841 tgagtaaacc atttttttac tttcgaacca aacaattcaa aacaactttt ggcatatttt
    33901 tcataggctt caaccgtttc tcggttcaac catccgcctt tttcttgcag atacatcggc
    33961 atatcgaaat gatacagatt cacaaagggt tcgataccgt tttcaatcaa ctcatcaaaa
    34021 taacgatgat agaaacgaac ggcttcttcg ttgattgttc cagattcatc aggtatcaaa
    34081 cggctccatt ggatagatgt tcgaaatgaa ttatgcccag tctgtttcat caactgtaca
    34141 tcctcttgat acttcgtata aacttgcgag gttttttcag gtcctacttg atcaaagaac
    34201 ttttgcggtt cttttttgta ccaataatca aaaatgttct ctccttttcc atcgcctgaa
    34261 atccttcctt ctgtttgtgg gccacttgct gcagaacccc accaaaaatt tgctggaaat
    34321 tgatattttt tcatcaaagc acctcttttt cttttttagt tcgttttagt tgattccatg
    34381 tatgatattt tccatcacaa tcactttttc attttcttcc tcttcttttt tgattcgttt
    34441 taacagctgt tctgctgctc gttccccgat tttatctgtt ggtggcgtga tcgtgatttt
    34501 cggaaggata ctcagatcgt ttttatctaa ataatcatag tgactgaacg caatatcctt
    34561 cccgattctg acaccttctt gattgaaaca ttcgatggca ccaatcgaca tattgtaatt
    34621 gctgacaaaa atagcagttg cccctttttc taataatgct tttgccccgt aatagccgct
    34681 ttttctagaa tagtctcctg taaagacctc taattggatc gatggatcat tttggaccgc
    34741 ttctttggct cctgctaaac gttctcttgc tacgtagtct gtttgagtgg cagcaataaa
    34801 tccgattttt ttatgtcctt gttcaccatg atgagcgatc acttttgcta cactttctcg
    34861 atcattcact aatattgtat caatacctgc tggtccttct ggacaattca atgcgataac
    34921 tggaatactc atttttgtga gcatttcaaa tccagaccac tcttcttcgg ataagaagac
    34981 aatcagccca tcgatcacat gcttcatcag gtattcaatt ttttgttcaa ttttttctgg
    35041 ctgatcggca aacccgctta ataataagct atacccattt tcttcagcta ctctttcgat
    35101 ccctgagaca acttccgacc caaaacggct ggaaatcccg tttatcaaaa gtccaataga
    35161 gaagcttcga ttattcttca accctttagc aatgatgttt tctttatagt ccaacgctga
    35221 aatcgcttct gctatttttt tcatgttctt ttccttcagt tgctgaccat tcaagtaacg
    35281 ggaaactgtt cccactgaaa caccagccat cttagccaca tcacggatcg atgccataca
    35341 ttctcactcc tgccagttac atttgatttc tctttcttgt tgttcgatta tgatgaccgc
    35401 attctttgca tagtgttgct tgtcatcaat atccatataa ctaaagtctt cagtagagca
    35461 acttcctctc actattaatt atacttaaac aagtatttga accggttcat ttttaatata
    35521 gcattttttt aaaagattgc aacacttttt taaaacgctt tctgaaagtg gcggattttt
    35581 tgccttttta aaattttatt ctaaaattta ctctatttgt gggtgttttg tgcgtttttc
    35641 tcttccatcc gtttgaagtt ttacattcca atggtataat ttctttatcc tatcaaatgg
    35701 gggaagtatt ttgaagaaat taatcgtact atttattttg tctgcgggac ttttgacatt
    35761 gactggctgt gatttgtttg gcggctctga ccaatcctcg gacgaaacaa ccgattcttc
    35821 tgtcttaaaa gcggaaaaag cagataccac caacagtgta tatacgctaa aagtacgtaa
    35881 agatatggat ttatccgcgg gacagttgac atttacagat aaaaaaatgg aatggacacg
    35941 cacgtatcag acacaaggaa ctgattcttc tgaatcatct gaagaaaaaa cagtgctgac
    36001 agatatcaag atcactacca aagatgacga atatattatt tcaggaaaag aaaataaaaa
    36061 agaaacaaca gtcatattta caaaaatcgg taattaccgt ttgaaggatg aggatggcaa
    36121 catctacagt ctatagtgcc gtctgttgga tcttcttttg tttctcccct tcttttctgc
    36181 tatagtaaag aagcaagatg attgtaaagg agacgaaatg gatgatcgat agtcctgatt
    36241 attgtacatg taataacaac aaaaatatcc atacagaatt taatgaccaa ggaagcttga
    36301 gcatatgcga caactgtcac aaactagtca aagattcatt taaaacattt gaatcttatc
    36361 ctgttcaaaa ttatgtaaaa agtagaagaa gataaacaaa tccaagcaaa actcactatg
    36421 gctgattttt atgaacttca aactcagctt cttcctttga tcaagcttca tcagtaaaac
    36481 aaacagtgga tcatttcagt ttacaaatca aagagtaaag atttatttat ttcaaatatt
    36541 tgaatataaa ataaccaaac gatagaaagg cttattctac atcacgtagt aatttttctt
    36601 tcccgtcgtt tggtttttta tttttagcct aattcttgac cttttgcatg ctggttatcc
    36661 gtaaaatatt ttccagcagg ctttccttcc aattcagcta atttttcttg gatctgacgg
    36721 atcacctttt ttgcatcttc tggattttct acaaaatcga atttatcccc atccacttgt
    36781 attttaggac atacatcaaa atcttcatac cattgattat agcgggtgtt caacgtttca
    36841 taataggtat ataacgtctc atcgctttct agctgttcat agtcacgccc acgttttttg
    36901 atacgttcta gcatcgtgtc caaagaaact ttgatatgga ccatcaaatc aggccgtttt
    36961 tttggagcaa catcatctaa ctcgtttagc atcgtatcta ataagctatc gtactgctgt
    37021 acttcgatat ccgttacccg acctaaatca gcgtttagat ggaacaacag gctatcttca
    37081 tagatggatc ggtctagcac attgtcatcg ttcactaaag catttttcat tgctaaaaat
    37141 cgcttgttca aaaagaagat ttgcaataaa aaagcgtact gctcaggatt tgaataaaag
    37201 agcggcaata cttcgttatc ttcgacattt tcataaaatg gtttagaatc aatctctttt
    37261 gcaagcatat ccgtcaaact gctcttacct gcaccaatcg ttcctgaaat caaaatcact
    37321 gacatacaac ccttcctctt ctataagtac tcgcctacgt aagtttcaac aggcaatgtt
    37381 tcaaaatcat attcacgtac agcttggtct gattttaaat acgtatggag actttgtgta
    37441 atcatcaagt tcgtaggtac cgtctcttct tgtacaatga tcatcggttt tttcaacata
    37501 gttgccacac ctaattcgta agccgttcct ggatcgattg tttgatgctc aaagtcaagg
    37561 atagcaacaa caaattctgc atttgtcagt tcttccatat ctttttcgta tacttcctgc
    37621 gcccatccag cgctgaatag ttcataattg ctttcttggt gatgacgtgg agagtagaaa
    37681 cttgtgactg ttttgttttc ctccaacgct ttttcgatac gacttactcg atcgatttgc
    37741 tcctctgaaa aaaatggtcc tgctaaatat atttgactca ttattttgcc tccttcaata
    37801 ataactgatt tttaatagat actgctcgta attcattgac cagttccaat ggattgttgg
    37861 aaaagattac ttgatccaac cattttttat ccataaaatc ctcttttgca aaagtttcta
    37921 ataattgttg caagccgctg taataaccgc caatattcaa tattccgatt ggcttgtcgg
    37981 gcgtcagacc gattgctatc caagaaagaa gttgtgagaa ttcctccaat gtacctagac
    38041 ctccagggaa aacgaggaca gcatctccct tttcaaataa taataccttt ctttcatcga
    38101 tcgtttctgt aggaataaat gtagtaacat cttttccagg caattcagtt tcaaaaagcc
    38161 cattcggata gatacctgtg acttttccgt tattttccag tactgtttta ctaatcactc
    38221 ccataatccc ggagtatgaa ccaccgtaaa ccagttcgat ttcttcttgt gccatgtatt
    38281 ttcctaacgt ttgcgcaata aatttgtaac tttctttatt accaaaacgg gaaccgcaaa
    38341 aaacagtaag tttcataaaa aaacactccc taactcaaaa gtctatcttc attctacacg
    38401 tgttttttta aaataaaaga ctagattttg tagtttttta gtggtatata ggatagacgc
    38461 cactatatat agtatttaga aaaaaatcat ttttcagcca ttttatagat aaaacaaaaa
    38521 taaataacgt gttttcatcg atatgaaatg acttacttat agaagatact gggatttcgt
    38581 cctatatgcc aataacgtgt attattttaa acaacaaata cttgtttctt ttattaacga
    38641 aaaaatcatt ttgttctcgt gttatgtttc actgataaat gatgtttctc taaataaaaa
    38701 agccgacgaa ctaaacgatc aaaatttgat catttttgtt catcagcttc tcctaaaaat
    38761 ctttttgtta acgataaata gctggatttg taaaaatatc acttgaatcg tcactgctgg
    38821 aagaaaattc agtgataacc gcacctgttg cgcctgcctg gaactagtgt ttgatattgg
    38881 gctcgaacgt gtactgatct ctagcatgaa gaataatttc tttttttact gtataataac
    38941 tttctttcct ttttggaata gtacaggaaa gtttttttgt ttcctttcct tcgacataag
    39001 gtataccaga ccctttcgac aacgaaaggt tctcattttt ccttcatcgt catttcaagg
    39061 agggtgccga tgctctggac agtttcgatc gctcctaaac caaaatctgt atattcgatt
    39121 ctttctaact ctgattcttt cataccattc ctgtctcaag gtacatctat tgtacttttt
    39181 tcttgtaatc cattctgcct ctcctaacta attgtcaaat catcccaaga tatgtcttct
    39241 tcctcttttt cttcttggat gatttctgca ttcggatcta ctggtttttt caataataaa
    39301 atggttattc ctgtgacaaa agaaccagct aacaatgcac caatgaatgc ccatggtctg
    39361 gtcatcgtag cgactgcaaa cattcccgat gccggaatac ggctatctgc gccccaaaac
    39421 atgcttaatc cgccacctac tgtcccaccg actcccgttg ctatgacatt gcgtgccaag
    39481 tcgttcaata cgatagggaa acatccctct gtgatctgac agatccccat aggaaaagcg
    39541 gtcttcaatg tatcgatttc ttgacgattg agtatatttt tacgaatgat tttccctaag
    39601 aaataagcga tcgtcaagcc gaatggggtt accatcgaag ctaaaatcaa tacagtgatt
    39661 ggttcataga ttccttctga aaatcgtgcc acaccccctt atccagaata aatggtaatc
    39721 cagaaacagc cgtgtatctg cggtaataag cctaaccaaa cgaaaaatat gagaagctat
    39781 ttttgtttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttttttta
    39841 tttatgtttc ataatcaata tggtaaggat gcagctccgt atggtagacc gcctccgaat
    39901 attcaatcat ttccccaatt tgcgtagacg atttccgtat ccgtttgatg ccgatctgtg
    39961 cgtctgtttt cagaattcct tgttcttctt ctgttaaaaa tactgccgag aaatcatcag
    40021 aaaatgagtc aatagtatat ccttttttcg tcagcaaacg atacaaagat tctttgccaa
    40081 attcttctct gctgaattgc atcatttctt gtggaagata atgaacaaaa taaatataag
    40141 gctgattgtt caaataatat aagcgcttaa aacaaacagc ttgctcaccg aaaaaggaaa
    40201 acaaaggatc ttccttcttt atatggacca attgcaaatc cagcgtttct ttccggactt
    40261 catatcggga gttctccaag atttgcgtaa agcttgccgc tttggataat cgattgtaag
    40321 gacgattgct tagaaccgtc gtcccacgac cacttttctt tgcgacatat tcatctgatg
    40381 ccagcagttc gattgccttt cggacagtga ttttgctgac ttgaaacagt tcttctaatt
    40441 cactttctgt cggcaacatc gaaccgactg gatattttcc tgagaaaata tcttctttaa
    40501 ttttatctgc gacttccaag tatagtacac gtgtcctttt cataacgtca ccctttgctt
    40561 tactattact aaaagaatag cacataaaaa ataaaaaaag aacacaaatc acatgtgaga
    40621 agtgtgttct ttttcattca gctgctttaa ttacaagttt acgccatttg aggcaattac
    40681 ttctttatac caatcaaaag attttttctt tgatcgattc agtgtcccat ttccttcatc
    40741 gtctagatcc acatagataa agccgtaacg tttactcatt tctcctgttg atgcactgac
    40801 aagatcgata catccccaag gcgtatagcc catcaaatct acaccgtctg ctactgcatt
    40861 agccatcgct tcgatatgac gacgtaaata atcgatccga taatcatcaa taatcgtgcc
    40921 atcctcttcc atatgatcaa tggctccaag accgttttca acaatgaata atggtttctg
    40981 gtaacgattg tataattcat tcaatgcgat tctcagccct tctggatcga tctgccagcc
    41041 ccattcactt gcctcaagaa acggattttt tactcctccc agcaagttcc cttctgaagt
    41101 tgctgcttgt ggatcagtct cattgattgc cgtagacata taataactaa atccgatgta
    41161 gtccactgga tattctttta gcaactggaa gtctttttcc gtttgctcta atttttccgg
    41221 atcgactcca tattttttat gggtacgcgc tgtgtatgca gggtattctc cacgtacttg
    41281 gacatccgtg cagaaaaaat tgaattcttg gttttggatc attgttgctg cctgattgac
    41341 tggattggca tcgatgctgt aagttgttgc atagataatc atgcagccga tttggatatc
    41401 cgaacgcaat tcgtggccga tttttacggc tttgctactt gcaacgaatt gattatgcca
    41461 tgcttggaaa atattttggt actctcctgc tccattgctt tttactaatc cttgacttaa
    41521 agctggaaag tgaaaggccg aattgatttc attgaaagtc atccaatatt tgactttact
    41581 gctgtatctc tctaatactg tctgagcaaa tcgttcatag aagtcgatca gttttcgatt
    41641 tttccagcca ccgtattctt ttgccaaatg aagaggcatt tcgtaatgag aaatcgtgat
    41701 cacaggttca atatcatatt ttaagcactc atcaatcagc tgatcataaa attctaatcc
    41761 cgcttcgtta ggagtacctt cgtctccatt tggaaaaatt cgtgtccagg caatcgaaaa
    41821 acgataacat ttgaatccca tttccgcaaa caaggcaaga tcttctttga aacgatcgta
    41881 atgatcgatt cctcgatgat tcgggtaaat atatttttct tgatcaatcg tccagtcaaa
    41941 ttcttcactg ccgataatcg caaagcgctg cttacctcca ggcatagcat ctgcaacgga
    42001 tagtcctttt ccgtctcgat cataagcccc ttctaattga tttggcagca gttgctccac
    42061 cccataaaaa tttttctgaa aaacgtgatt gcatcctgat ttcctcctta ttttacaatt
    42121 gccagaacat cttcgtttgc aataatctct ttttggtcta attcaagtat atcggcaaat
    42181 gcatcagtat tcgtaatgac aactggagtg attacgctat agccagctgc tctaattgct
    42241 tcgatgtcaa aacgaatcaa taaatctcct gctttgacga gatccccttg tttgactaag
    42301 atctcaaagc cattcccatt taattctact gtatccatcc cgatatgaat caaaatctcc
    42361 gctccgtcag tcgttgtgat ccctacagca tgtccagttg gaaaaatagt cgtgatctct
    42421 ccgtctgcag gtgcaactag ttctcctact tctggatcaa tagcgatacc ttttcccatc
    42481 acgccagaag aaaaaacttg gtctggtact tcactcaatg gcagtacttt acccgttaaa
    42541 ggacttttta aggtatgccg tgctgaagta atcggttctc ctgcattcgc atgtttgttt
    42601 tctaattgat tgtcttgtgt ttgttcgtca aatcctaaaa tcaatgtacc tacgaatgca
    42661 agaacaaaag caattcctgt agctattact gctactgtca catttgactc tacaccatcc
    42721 accgtattaa tgaaagtcgg aatcgtcaat aagctgacca aactgctgga gaaagctttt
    42781 actccggaaa atccgataat agctccacca atacctccag aaatacaagc ggcaatgaat
    42841 ggtttcttca aaggtaatgt cacaccatac acagttggtt cagtgattcc aaataacgaa
    42901 gtcactgtag aagaaatccc taatgctcga agtttcgtat cttttgttcg caatgctaca
    42961 gctaaagcag ccccaccttg tgccaagatg gctggaagaa gcattggcat caatacatca
    43021 aacccatatt gttcgatatt caaaaacatg atcggtacga atccccaatg catgccgaac
    43081 atcacgaata cttgccataa acttcccatg attagacctg ctacgattgg actaaatcca
    43141 taaatcgagt tgaagagacc gcctaaagca ttaccggcaa ccgtcccgat tggtcctaaa
    43201 gcaagaaatg ttaatggaac catcactact aaaacgacaa gcggaactaa aatcatttgc
    43261 agaaattgcg gaatcacttt ttttacgaat ggctctaatt tactttgaac ccatacggct
    43321 agaatgattg gtatgacaga agaagtataa ccagatggtg aaagaatcac tgggatccca
    43381 aagaaactga tagcttctcc cgcaccagca actgctgtga tagctggata cacaagtgcc
    43441 atagcaattg ctactgctaa aaactggttg gctttgaact ttttagctgc tgtaaaagca
    43501 agcatgacag gtaagaaggt aaagacacca tctgctgcag caaacaatat ttgataagta
    43561 ccgctatcag ctgtcagcca gcccatcacc gttgccaatg ataagaatcc tttcaatacc
    43621 ccggcggctg ccatcgcccc tagaaaaggt gtaaatatac tagagataat atcgatcaga
    43681 cgattcaaaa tatttttgga ctcttctttt ccatcctccg aaactgcaag accttcctca
    43741 tccacgatcg attgataaac atctgctaca ttactgccaa tcactacttg atactgaccg
    43801 ccactttgta cgacttggat cacgtccggg tcttctttta acttttgcgt atctgctaaa
    43861 gattcatctt ttaatctgaa tcgcaaccgc gtagcacaat gtactaaact tttgacattc
    43921 ttttgtcctc ctaccgcttc ccatacacga cgaccaactg cttgattatc cattgttttt
    43981 tccttctttc ttttttattt aaaaaataaa aacccagatt gaaaaaaaca gtcacaaaca
    44041 ttcgtgaacc tattttttca atccaggttt tgcctgccat acagtaacaa tccttatgat
    44101 tggatgcttt ttttctcact tactactctt tgaatatgaa tcgttaaata aatctgctct
    44161 gcgatcccca tttcctgttt ttgcgtttgt cgaagatact cattgatccg ttcgacacaa
    44221 tgaaacgctt ttggatactt tccttgaact aatgcgtaga gaaattcatc ttgctcgtca
    44281 gatccttccc ctttgagata acgctgggca aaaaactgca gatgagtaat gatacgctga
    44341 taattcaaag attcttcatc gaacacgatg ccgaagaatt tactgatgat actca
//
LOCUS       DAZKPE010000016        44178 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000016 DAZKPE010000000
VERSION     DAZKPE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.016"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            120..1121
                     /locus_tag="ACG930_000984"
     CDS             120..1121
                     /locus_tag="ACG930_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFQ0518158.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            1140..2159
                     /locus_tag="ACG930_000985"
     CDS             1140..2159
                     /locus_tag="ACG930_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFQ0518159.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2261..2977)
                     /locus_tag="ACG930_000986"
     CDS             complement(2261..2977)
                     /locus_tag="ACG930_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0518160.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(2946..3731)
                     /locus_tag="ACG930_000987"
     CDS             complement(2946..3731)
                     /locus_tag="ACG930_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0518161.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3722..4471)
                     /locus_tag="ACG930_000988"
     CDS             complement(3722..4471)
                     /locus_tag="ACG930_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0518162.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4769..5293
                     /locus_tag="ACG930_000989"
     CDS             4769..5293
                     /locus_tag="ACG930_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFQ0518163.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5309..6808
                     /locus_tag="ACG930_000990"
     CDS             5309..6808
                     /locus_tag="ACG930_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFQ0518164.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6896..7498)
                     /locus_tag="ACG930_000991"
     CDS             complement(6896..7498)
                     /locus_tag="ACG930_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFQ0518165.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7602..8558
                     /locus_tag="ACG930_000992"
     CDS             7602..8558
                     /locus_tag="ACG930_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFQ0518166.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRSEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8863..9819)
                     /locus_tag="ACG930_000993"
     CDS             complement(8863..9819)
                     /locus_tag="ACG930_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0518167.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            9993..10553
                     /locus_tag="ACG930_000994"
     CDS             9993..10553
                     /locus_tag="ACG930_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518168.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10546..11370
                     /locus_tag="ACG930_000995"
     CDS             10546..11370
                     /locus_tag="ACG930_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFQ0518169.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11380..11997
                     /locus_tag="ACG930_000996"
     CDS             11380..11997
                     /locus_tag="ACG930_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0518170.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12015..12698
                     /locus_tag="ACG930_000997"
     CDS             12015..12698
                     /locus_tag="ACG930_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFQ0518171.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13381..14664
                     /locus_tag="ACG930_000998"
     CDS             13381..14664
                     /locus_tag="ACG930_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0518172.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14680..15567
                     /locus_tag="ACG930_000999"
     CDS             14680..15567
                     /locus_tag="ACG930_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0518173.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15584..16420
                     /locus_tag="ACG930_001000"
     CDS             15584..16420
                     /locus_tag="ACG930_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0518174.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16423..17046
                     /locus_tag="ACG930_001001"
     CDS             16423..17046
                     /locus_tag="ACG930_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518175.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17043..18335
                     /locus_tag="ACG930_001002"
     CDS             17043..18335
                     /locus_tag="ACG930_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0518176.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18694..18791
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18907..19488
                     /locus_tag="ACG930_001003"
     CDS             18907..19488
                     /locus_tag="ACG930_001003"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFQ0518177.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19491..20798
                     /locus_tag="ACG930_001004"
     CDS             19491..20798
                     /locus_tag="ACG930_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFQ0518178.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21214..21702
                     /gene="purE"
                     /locus_tag="ACG930_001005"
     CDS             21214..21702
                     /gene="purE"
                     /locus_tag="ACG930_001005"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFQ0518179.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21695..22819
                     /gene="purK"
                     /locus_tag="ACG930_001006"
     CDS             21695..22819
                     /gene="purK"
                     /locus_tag="ACG930_001006"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFQ0518180.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22832..24127
                     /gene="purB"
                     /locus_tag="ACG930_001007"
     CDS             22832..24127
                     /gene="purB"
                     /locus_tag="ACG930_001007"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFQ0518181.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24307..24684)
                     /locus_tag="ACG930_001008"
     CDS             complement(24307..24684)
                     /locus_tag="ACG930_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518182.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            24940..25668
                     /gene="purC"
                     /locus_tag="ACG930_001009"
     CDS             24940..25668
                     /gene="purC"
                     /locus_tag="ACG930_001009"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFQ0518183.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25668..25922
                     /gene="purS"
                     /locus_tag="ACG930_001010"
     CDS             25668..25922
                     /gene="purS"
                     /locus_tag="ACG930_001010"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFQ0518184.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            25924..26595
                     /gene="purQ"
                     /locus_tag="ACG930_001011"
     CDS             25924..26595
                     /gene="purQ"
                     /locus_tag="ACG930_001011"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFQ0518185.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26596..28818
                     /gene="purL"
                     /locus_tag="ACG930_001012"
     CDS             26596..28818
                     /gene="purL"
                     /locus_tag="ACG930_001012"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFQ0518186.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28803..30242
                     /gene="purF"
                     /locus_tag="ACG930_001013"
     CDS             28803..30242
                     /gene="purF"
                     /locus_tag="ACG930_001013"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFQ0518187.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30265..31317
                     /gene="purM"
                     /locus_tag="ACG930_001014"
     CDS             30265..31317
                     /gene="purM"
                     /locus_tag="ACG930_001014"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFQ0518188.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31314..31892
                     /gene="purN"
                     /locus_tag="ACG930_001015"
     CDS             31314..31892
                     /gene="purN"
                     /locus_tag="ACG930_001015"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFQ0518189.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31889..33424
                     /gene="purH"
                     /locus_tag="ACG930_001016"
     CDS             31889..33424
                     /gene="purH"
                     /locus_tag="ACG930_001016"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFQ0518190.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33440..34714
                     /gene="purD"
                     /locus_tag="ACG930_001017"
     CDS             33440..34714
                     /gene="purD"
                     /locus_tag="ACG930_001017"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFQ0518191.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34836..35750
                     /locus_tag="ACG930_001018"
     CDS             34836..35750
                     /locus_tag="ACG930_001018"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFQ0518192.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35883..37448)
                     /locus_tag="ACG930_001019"
     CDS             complement(35883..37448)
                     /locus_tag="ACG930_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518193.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37441..38892)
                     /locus_tag="ACG930_001020"
     CDS             complement(37441..38892)
                     /locus_tag="ACG930_001020"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0518194.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(38906..39922)
                     /locus_tag="ACG930_001021"
     CDS             complement(38906..39922)
                     /locus_tag="ACG930_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0518195.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40142..41230
                     /gene="chvE"
                     /locus_tag="ACG930_001022"
     CDS             40142..41230
                     /gene="chvE"
                     /locus_tag="ACG930_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFQ0518196.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41284..42810
                     /gene="mmsA"
                     /locus_tag="ACG930_001023"
     CDS             41284..42810
                     /gene="mmsA"
                     /locus_tag="ACG930_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0518197.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42812..44017
                     /gene="mmsB"
                     /locus_tag="ACG930_001024"
     CDS             42812..44017
                     /gene="mmsB"
                     /locus_tag="ACG930_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFQ0518198.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
BASE COUNT        13971 a         7617 c         9765 g        12825 t
ORIGIN      
        1 cgtattagca aaataaaagc tttttttatt gtgaataaat gaacataatt aggaggagaa
       61 agatgaactt atttgacatt tttcgatcga ctttgacaga tatgtcgatt gtcagtgcaa
      121 tcacttcaac agtttttatt atattattag ggtttgtttg tagaaaaaag gggatttttt
      181 ctgaatctgt tggaaaaatt ctatcgaaag tcgtcttaac agtggctttg ccagcactgg
      241 catttcgagc tttcatgcaa gatatcaata cagaattact gatgcaagga atcaatgtct
      301 tgatttgggg attagttatt tatattattc ttattctagt ttcaaaacct tttttcttaa
      361 gctataaagg ggataagcaa acaacgttgc gtgtcctgac gatctttggt tctacgacct
      421 ttttcggaac gcctatcgtc agtgcgattt atggtcctgt cggcgtgatg tattcctcaa
      481 ttttcaatat tggctaccga atctttttgt attcttatgg atacataaaa atgagtggct
      541 tgaagatgga agctaaaaat atcaaagcga tgttcgtcaa tccaatcatt atcgctactt
      601 ttgccggcct tttcatttgg ctgttccaag ggtatctgcc acaagtgtca gttacaggtg
      661 cagaaggaga gataagccaa gtagcgtttt tgcgaattga ccagactgca ccgtggctat
      721 ttcagccgat ggattattta gctggtttaa gttcaccatt ggcgtggcta gcaatcggcg
      781 caacattagg tgaagtaagc ttcaaaaaag ctgcatctga aaaaacttca tggtattaca
      841 gtctagtcaa agtggtattt gtacctgcat tgaatatcgt gattctagca gttttgacgg
      901 caacgaatat tctaccagtc aattttgaag cactggcaac aatcgttatc atgatggcta
      961 caccagctgc aacagtggca gcagcctatg ctatcagttt tgatagggag gcacttttag
     1021 cctccaatgc atccttactg tcaactattt ttgctgtggt actgacacct gtatggatcg
     1081 ttgtattaca aatgattcat ggcataggtt tattttcata agaaatggag gaagaaagta
     1141 tgagaatcgc atgttacggt gttcgtccga acgagataga tttttttgaa aaattgaata
     1201 tttaccatta tgatctcagt ctttatgaag aactgttgac acatgacaat atcgtgtcag
     1261 caaaggacca tgatgctgta ttgttgaggg gaaattgtat agcagatgag accaatcttg
     1321 caaaaatgca ggaatatggg attcgttatg tttttacacg gactgtggga gtcaatcata
     1381 tcgatctaca agcggcagct gattttggta tgacagtagc ccgtgtacca tcgtattcgc
     1441 caaatgcgat agcagagtta tctttgactt ttgccatgat gcttttgaga aatactgcgt
     1501 atacgacgat ccgaacatct ttcaaagatt ttcgagtgga tgagcaaatg tttagtcgtg
     1561 aaatcagaaa ttgcacagta gggatcatag gaacaggcag gatagggttg acggaagctg
     1621 ttttgtttaa gggactagga gccaaagtga tcggctacga tattcatcag acagaagctg
     1681 ctaaaaaagt attgacgttc cactcgcttg aagagttatt agccaaaagc gatattgtca
     1741 gtattcatgt acctcatatc ccaggtgaaa acgatcaaat gatcaatgaa ggatttttag
     1801 ctcaaatgaa aaaaggtagc atcttgatta atacagcccg tggagagctt caagataatg
     1861 aagctatttt aagagctttg aaaagcaatc atttagctgg ttttgcaacc gatgtttttg
     1921 caaatgaaac agaggttttt ttccgatcct tcaagccatg ggagacgatt ccagaccctg
     1981 ctatccagca attagtagaa atgtacccta gagttcttgt aaccccgcat gtaggttcaa
     2041 atacagatga ggcattatca aatatgattt cgacaagttt cgagaacttt cgtgaaataa
     2101 tagaaactgg aaaaacgaaa aatgaggtat ctcttcctaa agcccgtcaa ttaagataag
     2161 aaaacatgga tattcgtcaa taaaatgttt aaaaatagtc caagtaaaca gttgttactt
     2221 ctgtatactt ggactatttt gtatgggata attcgatgac tcaacagtaa tctgtgagct
     2281 ttttccgccc attctttgtc aattcataac aggttagcgg ccggccgatt tccaaatatt
     2341 tgattctttc gttcaatata tcttgttcta ctaaaaaatt caaatatttc ttgacggata
     2401 tacgtgacag tgagcttttt tgagccagtt cttttgttga aaaaatagta tcttctttta
     2461 gaataaatgc acttattttt tttaaagtca gttttgacag acctttaggc aaatcgatga
     2521 atgatggtat ttcgtgaatg ggagtggtgt ggttgaatac ttgatcgatc aatttctgat
     2581 cggctttttc agtcgtttgg attgtctgag agaaagcaag atacttttcg atcgccagct
     2641 gaaaacgttg caaagtgaac ggtttgatca aataatctaa ggcaccgtag cggatcacat
     2701 tctttatggt ttcgatatca tctgcagcag tgatcaaaat cactgggata tcatttcctt
     2761 gctgtctaag ccaagataaa aaatggatac cactttcgcc aggcatgtat acatcaagca
     2821 gcagcagatc tgcgtttttt tgtctgaaat atttttttcc ttcttctaca tttctgaaac
     2881 tttcgattac gttcatatta gggatgcttt ccacaaaagt acgattcaat tctgcaacca
     2941 ttggatcatc ttcgattatc aggacatttg tcatcatttt gatcttcctt ttttggtaat
     3001 tctagataga cgattgtacc gccatttgtt tgtttggaaa attctaaaaa tccaccgtgg
     3061 cgtttgacga ttgaatggat gagattcaat ccaaacccac gattgattcc cttcgtcgaa
     3121 aaacctagcg taaatatttt ttctgagatt tcttctgata tcccgacacc gtcatcgcag
     3181 acggtcacga tgaatacttc agcttctgtg tcatagttta aatgaatccg gacctgtccg
     3241 tttctttcat gtttttgtag cacggcttct tttgcattat caagtaagtt ccctaacact
     3301 tgcaaaagtg aatggatgga gtcatccatc tccattttag ggataaaaga atcgctttct
     3361 aacagcattt caacagattg ttctttggct tcgtttattt tgcctaataa aaaaccggca
     3421 attgcaggta ctttgatcag acttgagact tggccaatct cttttttata attttgattt
     3481 agctgctgga taaaatgggt gacttcttca tacttcttca aatcaatcaa accagaaatg
     3541 acatgaagtt tattcatgaa ttcatgggtt tgagctctca tggagtttat atattgtttc
     3601 gtccccccaa gctcctccat taatttcatt acttctgatc gatttcgtaa agttgcgact
     3661 gctcctaaaa aacggtcatt gctaaaaaga ggtgtaacgc tagaaatagt ttctatccca
     3721 tttaaataca tggattgagt ccgaacggtc gtttgatgct caatcgtctc tttaaacaaa
     3781 acgtcatata gattatcact gatttttttc ctacttcgaa atccaatagc tgctctgttt
     3841 ggtagaaaat gttttttgca ggtgtattga tcaagaggat agttttatca gaagagatgg
     3901 ctaagattcc ttcatctact tcattttcga taatcgtttt ttcacttaac tgttctgcta
     3961 tttcttgtgg ttcaagtcca agcagtactt ttttcatttt ttgggcaaga aaaacggcgc
     4021 ctatgatgcc tacgctaagt ccaataatca atgaaaaaac aatcattttt tgtccatctt
     4081 tgacttgatt gtcaatcgtg ttgtttgtta agccaacaca aactgcacca ataatctctt
     4141 gatcataata aatagggacg aaatagcgga agccgaaccc taacattcct tctttttcag
     4201 agaaaaattc ttgtcctcca atcacttttt tcacatcttc atgacttgag aaaggaagac
     4261 cgatgtaact tgggtctgcg tgagaatatc gaatgccttc agggtccatg acaacgataa
     4321 aatctaaatt cgatgcaatc atgatttcat ttgttattcc ttgaatcgca tgtgtcgggt
     4381 caccagtctg cagctttttt tggatgagtt tatcattggc aacgatttta gcaatgctag
     4441 agattttatc tgacacacta gatcggttca tcgaaagaat aaaattcctg atcaatatgg
     4501 cagaaacaat caaagaaacg aatgtggaga aacaaacgac aaggatgatc gtgttctgga
     4561 gctttaatgg ttttttctta aaaaaaggaa acataggcta cctcgaaaga atttattgtg
     4621 aaaattttaa catgaaaaca aaaatttaac aaattgtcaa cgataaacac aaccttccta
     4681 taaaaaacac cactgagtcg gtaaaagaag ctatacagaa ttttcaaaca ttggtatgat
     4741 agacgtagaa atggaaggag gcgtgtatat gataggggga atcgcacttg agacgattta
     4801 ttggtataca ttgctgattt gtgcaggatt ggcagtccta ttgattattt ttggagatgt
     4861 attcgatttt gatggcccgc ttgatccgat gcttattatc ccttggttaa ctttcacaag
     4921 cttatttggt tttctaggtg agcgtttaac agatcaatca tctttatttt tatttattgc
     4981 tagtggaggc atatcgatag tgttggtatt tttgcttaat ttctatatat tgatgccgat
     5041 gaaacatgcc gaatcaacga tgtcgtcttc tgaaaaaact ctggaaggac aagtagctgt
     5101 tgtgatcaca ccgatccctg tacgaggtat gggagaaatt cagttgaaaa gtgttaccgg
     5161 ttccattagt cgtccagctt gtttttacag cccccaagaa cagacagctg agcggggaac
     5221 gaaagtattg atcattgaga tcaaggaaag aatctgttat gtcatgcctt atgaaagcat
     5281 gataaaagct taaaggagcg tgtgttaaat ggaaatacca gttgttttta tcgcgatcgc
     5341 aatcgcagct ttgattttac tgatgttgct gatcgtcttt gtagcgaagt accagacagc
     5401 aaaaccggat gaagcgttga tcatcagtgg aagttattta ggaagcaaaa atgtgcacat
     5461 tgatgaaagc aataacaaaa tcaaaattgt gcgtggaggt ggcgcattcg tcttgccagt
     5521 ttttcaacgt tcgaatcgga tcagtctatt atcgagtaaa ttggacgtct ccacccctga
     5581 agtgtatacg gaacaaggcg taccggtgat gtgtgatggt acttcgatca tcaaaatcgg
     5641 ttcatctgta gaagagattg ctacagcagc agaacagttt ttaggcaaga caagagaaga
     5701 actggaaaat gaagcaagag aagtattaga aggacacttg cgctcgattc ttggttctat
     5761 gactgtagaa gaaatctatc aaaatcgcga taagttcagt caaagcgtac aagaagtcgc
     5821 ttctgtagac cttgcaaaaa tggggttgat catcgtttct ttcactatca aagaggtcag
     5881 agacaaaaac ggttatcttg actctttagg gaaaccaaga atcgcccaag tcaaaagaga
     5941 tgcagatata gcagaagcgg aagctctaaa agaaacgcgt atcaaaaaag ctcaagcaga
     6001 aaaagaatca caagcagctg aattacagcg acaaacagag atcgcagaat cattaaaaga
     6061 aaaagaactg aaattagcaa cctacaaaca agaacaagat gttgctaaag caaaagcaga
     6121 ccaagcctac aatttagaaa gtgcccgagc acaacaacaa gtaatcgaac aggaaatgca
     6181 gattaaaatc gtagaacgtc aaaaacaaat cgaactggaa gaaaaagaaa tcacacgtcg
     6241 tgaaaagcaa tatgattcgg aagtgaagaa aaaagcagat gccgatcggt acgctaaaga
     6301 acaagaagca caagctcaaa aagtcaaaga agtgactgaa gccgaagcag aacgattccg
     6361 tgtggaagca ctggcagaag cggaagccaa taagacacgt ttagctggac aagcagaagc
     6421 cgaagcagca ctagcaaaag gaaaagcaga agccgaagca aaacaaaaga tcgccaatgc
     6481 cttcaaggaa tatggcgaag cagctgtctt gagtatggtt atcgatatgc taccgcaatt
     6541 gatgcgcgaa gcagcacagc cgctaggaaa tatcgaaaaa atctctgttg tcgatacagg
     6601 aagcagttca ggagaaacca gtggagcgaa ccgagtgaca aattatgcca caaatttgct
     6661 ttcttctact caagaaacac taaaagcgac aacaggactt gacttgaagg aaatcgtaga
     6721 gaatttgtcg acacgtggga ctactagcca agtaaatatg tatgaagcgc caaaagaggc
     6781 agaacaaaac tcgatgaagg aagaataaag tagtacactt caccgttcaa tcaaaaatgg
     6841 aggaagactt tttaaagttc ttctctccat ttttttattt tattgcaaaa gaaaattagt
     6901 cctcgctatt tttcttttgt ttttggatct tagcttctat ctcttgtaaa tttgttctta
     6961 gcaatcgttc tttcttttgg agttcgacca aatcttctga tagttcttcc ttcttttctg
     7021 tttcaggagg acgaagaaag aaattgatac cgattgcaat gaatgtccct ataaaagtat
     7081 ctagtacacg ttggatagca tacaaagcgg attcgccttg agggatgctc aacgcaatca
     7141 gcaacaacgt agctattgcg gaaatgatac cggaattatt gttaatacca tctgacacga
     7201 cgatcacaat aataactaga ataggaagca agatcaattc taccaaaaaa tcattgtgaa
     7261 aatagctttt gacaaaaaaa taaatgatag ctaatgtacc acctaatgta ttgccgatga
     7321 tcctagactt tccaaaagaa acggttgtag tcaagtcctg acgcaaagaa aaaacagcag
     7381 ataatgcagc aatcatcggg attcctcgtt gagtcaaatg aaaaaacaag atacataaaa
     7441 aaacagctaa ggcacttttg atcgtacgca tacctagtcg aaaacggcca aattgcatag
     7501 agattctcct ttttggtctt tttactatca tacctaaact tttgtctgat agctagtttt
     7561 tcattattca agtataatta aaataaaaaa gggggaagta aatgcgtata ggaatgcgaa
     7621 cagtcaaaac agtgatcagt gtcttctttt cgatggtcac agcgggtagc ttatcgctgt
     7681 tgtattggcc agctgcaggg atcattgcat tattaagtgt aggaaatacc aagcgctcta
     7741 cattgcgtac gggcatgaat cgaatcgcag cctttatatt agctacggca acagcactgt
     7801 tcagtttttt tgctgttggg tatactattt ttggcttcag tcttttttta ttcctgttca
     7861 tcccgcttgc ctctcgcttc aaattaaccg aagggatagt agtaaattcg gttttggtca
     7921 ctcattattt agtggaggaa aacatgtctt ggcagctgat cggcaatgaa gcgggattaa
     7981 tggcgattgg attagtattt gctttgcttg caaatgttta catgccagat cgtacgaagc
     8041 agctgaagga aaaccaaata cagatcgaaa aagaatttcg aaatattttg agacaaatgg
     8101 cagaatttct tttatcagaa aataaagaag atgtgcagat caaatgcgaa catttactga
     8161 cattcattcg cgaaagccaa gaagatgcca gagaacatca agaaaactac tggctcagac
     8221 agccgctata ctacgaaact tacttctcta tgagaagagc acaggccaat gtgattaaag
     8281 acatgctgga aaatctagag agaatccagc aaccagctta ttatggaaaa catatctatg
     8341 gtttattgat ttatactgca gaaacatttt cagagtcaaa tgatggcaga caaattttaa
     8401 cacgtattga agaagtttat gtattgtatc ggcaaatgcc tctgccgact agtcgctctg
     8461 aattcgagga tcgagcagaa ttgttccagt ttttgcagtc ttttaaaagt tttattgaaa
     8521 tcaaggcaga attctcccaa caaaaaatcc aaaaatagag gttgtgaatt cagctaatat
     8581 tcaggtcaaa aagctgattt cacaacctct tctttaaacg gtgttctcct gtcaactcct
     8641 cggtcacaag tcacaatatt caacaaacat gagaagctgt tttttgaaat tgctccttgt
     8701 gactcggagc tgaacggtag gctcacaacc tctttcttaa acggtgttca aaagctttcc
     8761 tctgcggtaa taagtccagc caaacgaaaa ataggaggag ctatttttgt ttggctgttc
     8821 ttattacttg atgcagaaca gctttttcac aaccttttaa aattacatat ttttccatag
     8881 aacttgcatt tgatccaaga tttcgatgac atcttttgtc aagaagagag agcgattggg
     8941 caagtcacct tcaatcatgt gtaccatatt ctttatttcg taattcattg cttcagatgt
     9001 attcccgctt tcgatgaatt cctttgtacc atctgtaaat aagatctccg cacgatcagc
     9061 acgcgggtaa tcagcaatcg tcacataacc gttctcaaag gcaacgatac cgacttttgg
     9121 catttttgcc tgaaaagtca agctgacagc agcaagttca ttttctttgt tacgcaagat
     9181 agtgacggat tgttcgtcca cgcctgtttc aaaaggaacc attgtagagg caactacttc
     9241 aggttgagag ctcaaaaaga aacgagcgaa agatacagca tacgtaccga tatccaacag
     9301 agctcctcca gctaattctg gattgaagaa ccggttttta gggtctggtt ctttgtaact
     9361 gccgaaaggt gcttggatca tttttaaagc ccccagtttt cctgtatcca ttattgagcg
     9421 taactgctga taaagtggca tgttgaagat tgtcatcgct tctgctaaga tcaaattctt
     9481 ttcttctgct aagcgcatag cgtcagccag ttctttttta ttcatcgtga tggctttttc
     9541 acatagaacg tgtttgcctg cttccaatgc tgccaagata tggtcgatat gctgtctatt
     9601 tggtacagca atgtacacga tgtcgatttc agcatcgtct aacatttctt gatagcttcc
     9661 gtaagctttt ggaatattgt aacggtgagc gaagttttcc gctttttctg aagttctgga
     9721 agcaactgct gttagttcgc tcgtctcttg attgaagctt tcggcaaact catgtgcgat
     9781 ggtaccaaga ccaacgattc cccattgata ttttttcatc tgaaaacgct ccttcatagt
     9841 tggattgagt ttcttgtctg tctattatta taacaaaaat cacgaagaat aaagaggaga
     9901 ggacttgaaa cattaaaaaa aatgaaagca gcgatttaag aggtgctttt tgatcaaaac
     9961 ttaagtagaa tagttaaaag gaggggataa acgtgcatca agtatatatt gatcttatta
    10021 tgagtgtatt attagaacag tttgaaactg aaaaaaattt tttagatgaa tacttgctga
    10081 tcagtccaga acaatggcaa aaatggaaag atggcgagaa aaatctgcca tctgaagcga
    10141 tgcagaaagt aaaaaatctt ttcactgatt atgaatggat gctaacgcaa aagattttgc
    10201 gtcaaacgat tatttttccc gaaaaacgaa acgttgccgt tgcagagtac aagcaaatca
    10261 aaacacgcat cgcgcaaaaa tggcttagca gcaaagcagc aaaagtcgag ctgatccctt
    10321 tgaaaaataa tcagcaggct ggtagatacc ttgacttgaa agtaagtatt caatatgatg
    10381 aatggggcta tgatgatatt ttgaattttc gtctgccagc agatgttcaa aaacagatcg
    10441 aaggagaaaa aatcgaactt ctcgattggg tgaatgaaaa tctggaagaa acttacgttc
    10501 atgaggcgaa tggggaacgt gaagaacaac gaaaggattt ttcaagtgaa taaattttta
    10561 ggatttggag cagttgtgat tatgatcgca gcaatgggct atgttatttt tagcgatgat
    10621 gattcgcatg ttcaagccgg caatcaagca gtcgaacgaa caagcaccaa aacaactgct
    10681 agtaaagaaa agaacagtca aacaaccagc agcaaggtaa aggacaaaga aacaaaagat
    10741 cgtacgtcca aacaattgcc agatgttaaa acagacgatt ggaagctagt tttggttggt
    10801 ccagatcaca aattagaaaa agaaattgat gagtctactc aattggcatc attaagtaac
    10861 ggatacttga tcgacaaacg cattgctcca gaatatgaag catttgccaa ggctgctgaa
    10921 gcagctggat ttccattagt gatggtctca gcttaccggt ctgtatcatc ccaacaacaa
    10981 gttttcgaac aaaatgtcca agatgtgatg agtcgtcaag gtgtatcaga agaggaggcg
    11041 acaaagatta ctaaagaaac gattacggag ccaggataca gcgaacacca cacaggtctg
    11101 gcagtcgatg tcgtcgatca aaactggtac aacagttatc cttctactgt attggatgca
    11161 agttacggag atcagcctgg agctaaatgg atcgcagata atgctgcgca gtatggattt
    11221 atcgttcgtt atccaaaagg acacgaagat ataactaaga tcacatatga accttggcac
    11281 ttacgttatg tcggtaaaga aaacgctgag tatatcacca aacaccaatt gacgctagaa
    11341 gaatatctga atgaattaaa tgaaaagtag gaattgatca tggcgaaaaa aaagtggaaa
    11401 aagcaaaagc gcaagaatat ccgttggcca gcagtggttg ccggtgtagc agtgatactc
    11461 ttagcctttg ttttttcctt gaagaatctg tcttctcctt ttactgataa tcagcaagaa
    11521 aatgaagcgc aatcccatca gcaatttatt gaacggcttg ttccgcatgc ccaagaacta
    11581 caagatggtt atggagtgct tcctagtatc attttaggac aagctatatt agaatcaaat
    11641 tggggaaaaa gtaccttggc tagcaaatac aataatcttt tcgggatcaa ggcttatggg
    11701 gatcagaaga aagtaagcct ggaaacaaag gaatttgtta acgaagaatg gataactatc
    11761 caaggagact tcaaagtgta tgattcatgg gaacagtcca tggatgacca tacacaactg
    11821 ttcgtccaag gagtagattg gaatcctgcg ctgtatgaaa aagtgattac ggccaccaac
    11881 tatcaggaag ccgcacaagc attgcaagat gcaggttatg cgacagaccc cggttatgcg
    11941 caaaaaatca tccaggtcat cgagacgtat caattgaatc agtatgaccg gagatagcaa
    12001 aggagaagtg gctgatggca gaacaattta cgccagaaat catgacggaa ttgagaaaag
    12061 atatcgtaag agtaccggaa atcattttag aagcaagcgg gatcaagata tttggaaaat
    12121 tgatccgttc gatcatcttt actacggata ttgcgatcat acgtaataca aatgcgaatg
    12181 cagtaattgc tgtgtatcct tttacacctc atccagcgat tactaaaagc attattgagg
    12241 cagctgacat tccagttttc tccggtgtag gtggtggttt gacacaaggt gctcgttctt
    12301 cctacatgag catgttcgca gaagcgcaag gttcgttagg ggtcgttttg aacggtccta
    12361 cgcctttaga gacagtaaaa gaagtttgtc gagtagttga tattccagtt atcagtacgg
    12421 taacgtcgaa atatacagaa atagatgaaa agttagcagc tggtatttcg attatcaata
    12481 tcagtgcagg taaagaaact gcagaagcag tacgccattt tcgtaaaaaa tatcctgaac
    12541 ttcctatcat tgcgacaggt ggtccaacgg aagaaagtat tgctgagacc attcaagcag
    12601 gagcaaatgc catcacatat acgccaccaa gtagcggaga gctttttagt cgtaaaatgg
    12661 aaaaatatcg ggaaactgag aaaaagaatc atgaataaca ggtgagaatc aaaagacgag
    12721 gaagagcaga tagtggctct tcctcgtctt ttgtactcca gtactatttg ttcagaattc
    12781 aaaaaaaaga gaaatttttt tgttttttta cctgtaatgt acataagaag agttaaaacc
    12841 ttttgttatt attagcattc taacaaaaaa atgtcttgat ttattgaagc gctttctata
    12901 gaatgaaaaa cgaataaaaa ctaaaaaagg cacccgacaa tttagtagca gctaaattgt
    12961 cggggcttga aaagtcagcg ggaactgacc aatcaagttg ccatagtcaa tgcttgtgca
    13021 tcgacgtgta tattgtacct aatttcatac agaattacta gttatttttc tgttttttag
    13081 ggaagagcgc acacgaagaa gcatgcttat ttagctatgt caaggatatt gggcagttgt
    13141 ctgatatcct tttttctttg cgtaattatc ctcccatcat tgaagcaaga agtgttttta
    13201 gcgatgaaag aagaatcagc actatctaat ttttcttgaa agtattgagt tgttcatcct
    13261 aggcagaacg ataaggcaag tcttggtttt tattcccctt gaaaaagatc gtttaataaa
    13321 tatgttctgt ataaaaatac agtatattga aaaataacaa tggaagtaga ggtgcagaga
    13381 atgaagaaaa gaatgagaat catcttagct ttaagtgtta tgttattctt cttgacggct
    13441 tgtgggcaag aagatgacaa aaaaatcacg ctgaacatgg cttggtgggg ttcgcaagtc
    13501 cgacacgatg caacagtaaa agtaatcgag ctttatgaag aaaaaaatcc ccatgtgacg
    13561 atcgattatg aattttatga ttatgaagga tattacacaa aattaggtac actagcagca
    13621 tcagatgata tctgggacat tttccaactg aacaatcaat ttcctcaata catcaatcag
    13681 attgaaccat tagatgaata tgtggagcaa gggataattg atatttctaa tgcagatgaa
    13741 tcctatttag caacgacgac ttacgacggg caattagttg gactgtctaa cggggtgaat
    13801 tcgtttgcga ttgcttacaa taaaaatata tttgaacaat taaatatccc tgaaccagct
    13861 tcaaattgga catgggatga atttgaacaa atcagctatc aaatcactga agaattagga
    13921 atctatgcta tttcaagatt cgaagatttt atagctggct gtattattca aataccacaa
    13981 gttgagaaag gattgaattt ttataatcgg gaagatctat ctaacagctt gggatttgaa
    14041 aatccagact atctaacaga ttttttccag ctgcgtaaaa atctggtaga caaaggggcc
    14101 catccagaac caggtggtgg agctgcaagt acgacggatc tgtcttttca ggcggttagg
    14161 gatagagaag cggcaatggt gtttctatca agtaaccagt tgacagaaat attgtcaggg
    14221 gctcctgaag atatggagat tcagttgatt aatccacctc gcagaaaagc agatggagaa
    14281 tctggtatcc ctttacgttc ttcgcaaatg ctgagtatgg caaaaagctc agcccataaa
    14341 gaagaagctg ctaagtttat tgatttcttt caaaacagtg aagaagccaa tgaaatttta
    14401 aaaggagaac gtggtgtacc aatcatgtcg aatattcgag aacagctcgc tcgtgcagat
    14461 gatgcaactt tgcaagcgac atttgattat ttagaaatga tttccgatat ggacaacggc
    14521 gaagtgaatg tctttgatag tgctttgaat ccggaaattc aagaccaata caatctttta
    14581 gttgaaaaag tcatttatga agaagtaaca gcagaagaag cagcagagag tctttatgag
    14641 tttgcgtcaa acattctagg atagcagcag gaggaaggca tgaaaaaaga aaaactaaaa
    14701 cggttcttgg atcaagacaa tgtggtcggt tacgtatttg cttctccatt catcctagga
    14761 tttctattga taacagtgat accgatgatc ttgtcacttt attattcgtt caccgattat
    14821 cgtttgggaa atccagtctc atggatcggc ttggataatt atataaagat gctgagtgat
    14881 gcccgttttt tgaactccat ccgagtcact tttctctatg tatttgcatc tgtacctgtg
    14941 aaactgatct ttggtctatt gattgcttat cttttaacga ggaatatcaa aggaacgact
    15001 ttctttcgtt ctttgtatta tgtgcctagt ttgatcggtg gcagtatttc tatcgctcta
    15061 gtttggcggg agttgttttc taaaaacggg ttagtgaata ttttcctgga acgattaggc
    15121 gcacctgcgc tttcctggtt tagcgatcaa aaactggtca tgatccctct tgttttgatg
    15181 tctgcttggc aattcggttc ggcaatgatc atctttgctg caggtatcaa agagatccca
    15241 ggctcgtatt atgaagcggc agagatcgat ggagcgaaca aatggcagac gttttacaag
    15301 atcacgttac ctcttctttc gccgatcatt ttgtataact tggttatgca gacaatcgcg
    15361 gcgtttatga cttttacgca ggcatttatc attacccaag gtggtccgaa tgatgccacg
    15421 aacttttatg ctctttatgt gtataaccaa gctttttctt ttaattctat ggggtatgct
    15481 agtgctattt cgtggatcat gctgttgatt atgggagctg tcacctttct gattttcaaa
    15541 tcatcaaaaa aatgggtcgt tgtgtgaatg agaggaggaa gaaatgaata atacagtaac
    15601 gaaatggttt caatacggtt ttattttgct attaggtcta gtcatgattt atccggtctt
    15661 atggatgatc gcaggttctt ttaaaacgga tcaagagatt atgagtggtt cgctgaattt
    15721 gattccagag acttttcaat gggaaaatta cgcaaaagga tgggcggggt ttgctggaat
    15781 ttcatttttt actttcttta ggaattcgtt tgtcatctct gcagtttcga cgatagggac
    15841 agttctgagc tcgacttgta ttgcttacgc attatcgaga atcgatttca aaggaaaaag
    15901 attctggttc gtcgtcatgt tagtaacgat gatgattcct gcacaagtga ttttgattcc
    15961 gcagtttatt atttacaatc ggctgaattt ggttgggacg tatgtgccgc tgattttacc
    16021 acattttttt ggacaagcat ttttcattta ccagatcatg caattcatgg tcagcatccc
    16081 caaagagtta gatgaatcag cgattattga cggatgcagc aagtatagtg tctttaccaa
    16141 aattattttt cctttgctga aaccttcgat catcacgacg atcatcatcc agttttattg
    16201 gaaatgggac gacttcatgg gaccattgat ttatttaaac aagccgagat cttacacggt
    16261 atcgattgcc atcaaattat ttgcagacgc tggatctagt acgacttacg cgagtatgtt
    16321 tgcgatgtct acgttgtcgc tgctaccggt ttttctgatt ttcttattct tcaataaata
    16381 tcttgtccag gggatcagta caagcggtct gaagggctga atatgaaaaa gccaatagaa
    16441 gagatgtttc tttacaagct caactactat gtctgtcgga tttttttaac cagtcttatc
    16501 agtaatgctc ttttcgcttt agttctagga tgtttgttca ctttaggatt agtgctgtct
    16561 gctcgtgttg tctatctgat ttattttttg atgatgtatc cttcttatta tctatctgtc
    16621 cattacttgg cagaaaaaaa ggtatgttgg aggaaaggaa aaatcaaacg gatgtgtttc
    16681 atcattacgt tgtttcagct gtttgtcatt atttttgcag ttgattggta tttattagtg
    16741 ggaaagattg gagcttggta tctgattcct tttctattgt gtctgttgct ttttgtatcc
    16801 catagttttt ttagtacgct aattgatatc tgcaaagaag ataaagcaga tagtcttgtt
    16861 tatttgatca aaaggaatat ctggctgttg tcaaaaaacg tcaaggggtt tctgtggtat
    16921 ttatgccttt tgtatggact gttctggtgt atacagcatg attttttact cactgcatta
    16981 ctgtatccag ggctgccatt tgtcacagta ttttgcttaa aagaaaagga gaatgacttt
    17041 aaatgaagaa aaaatatgta caagtcggac ttggtgggag agcgcgtttt ttttatgagg
    17101 caattgcctc tacgtatcat caaacttgtg aactagtcgg tttttgtgat gtatctcaaa
    17161 caaggatgga ttatgcaaat cggatacttg tgaacaagta tggacagaaa aaagtaaaga
    17221 catgtatgcc atcacaattt gagcaactac tggatgacgt acggccggct gaagtcatta
    17281 ttacgtcagt agatcgaacg catcatgatt atatcattcg tgcaatgaaa aaaggatatg
    17341 atgttatttg cgaaaaacct ctgactatcg atgaggaaaa agctcaagaa ataataacgg
    17401 tccaaaaaca gacgggaaga agcctgcgag tcacttttaa ttatcgttat gcaccgtatc
    17461 acacgaagat aaaggaactg atagaaagtg atgtgattgg tgatgtgttt tctatccact
    17521 tcgaatggct gttaaatacg caacacgggg cagattattt cagaagatgg catcgaaata
    17581 agcacaatag cggcgggctt cttgttcata aatctaccca tcattttgat ctagtgaatt
    17641 tttggttgaa cagccgtccc caaaaggtat ttgcattcgg tggattaaac ttttatggga
    17701 tgcataatgc ggagaaacgc ggagtagaaa tattttacag tcgatgctat ggaagcgaac
    17761 tagctaaagc tgatccattt gctatagacc tgtcagccaa tgaggaattg cgagaaatgt
    17821 atttagaagc agaaaaagac agtggatata ttcgtgaccg cagtgtattt tccgatgata
    17881 tctctattga agatacacta ggcgtaacgg tcaaatatga aactggtgcg attttgacgt
    17941 attcgctaaa cgcgtatatg ccgtgggaag gattcaatgt ttctttcaat ggcagcaaag
    18001 gacggatcga aatgaaagtg atcgaaaagt cttacatcaa tgcaggtgga gataaaaagg
    18061 atgaaggagc agccgttctt cagtccatcc atgtctatcc gatgttcggt gagccatatg
    18121 aggtaatcgt cgaacaagaa gcgggcggac atggcggagg agatccgcgt ttattagatg
    18181 atctatttgg tgaagaaaaa gaagaagatc cgtggaatcg ggcagcaact cacgtagatg
    18241 gtattttgtc gattttgaca gggatcgcag caaatcattc tattgcttca ggaaaagcag
    18301 tagtgattga cgagcttgtc agcttaaaag aataagaata gatttacgga aattacttcc
    18361 cgtagtttat aaaatcttgc cttattgccg ataggctgtc ttttgaacac tatttattcg
    18421 gaaaaagggg ctatgacatg ctttttgtca tgccttcttt ttatgtgggc tgctttttta
    18481 gataggagaa aataaaaata actatttaaa cccgaacaaa aaggaataat gcattaaaaa
    18541 tcattagatt ttacaaaaaa ataagtaaac cacgttgtca gtttcagaaa gtagtgttag
    18601 actgttttca atatttgaaa caacattttt tattcaaata tggcaaactg ccttcacgtg
    18661 caaaacagtt gcaagaaaat gaatttacac tattattagt tttacatacc tacttatata
    18721 tcgtcataat atggatgaca gtttctagcc agtaccgtaa atgctggact ataagtaaaa
    18781 gattggctat ttcacccttc ttttcttatg ataaagtgga gggtgttttt ctttaacaga
    18841 aacatagtag gtttttgcac aaaagcggtt atttcggtat taataaatga taaaggagca
    18901 aataaagtga aagaattagt tgaacgtatt caaaaagacg gacgtatatt aggcgagggc
    18961 gtattaaaag tcgacagctt cgtcactcac caagtagacc ctgtattgat ggaacaaatg
    19021 ggaaaacggt ttgcagaagt atttaaagaa caaggaatca cgaaagttgt gaccattgaa
    19081 gcttctggga tcgcaccagc tttatttgct gcaagagaat tagatgttcc aatgatcttc
    19141 gctagaaaag caaaaagttt gacgatggat gaagaattat tgacagcttc tgtttattct
    19201 tttacgaaac aagtgacaag tacgatttct atttctcgta aatttttatc ttcagaagac
    19261 aaagtattga ttatcgacga tttcttggca aacggacaag cggcaaaagg attgatcgaa
    19321 ttatgccagc aagctggagc gcaagtagaa ggaatcggga tcgtcatcga aaagtctttc
    19381 caagatggac gtcagttact tgaagaaatg ggattgagag tcgtttctct tgcgcgtatt
    19441 gcttccttga cgaatggaca agttgagttt cttgaggagg acgcataatc gtggaaaaag
    19501 aaacacaaaa tggaaaagct gcggttttag ggctgcagca tctgctagcg atgtatgcag
    19561 gagcagtagc ggtgcctctt ttgatcggta caggactagg ctttaatcaa gaacagatga
    19621 cttatttgat ttcaattgat atctttatgt gtggattagc gacattattg caattgacag
    19681 ttaaccgatt tttcggaatt ggcttgcctg tcgttttagg atgtgcgatc caagcagtag
    19741 ctccactgat cttgatcgga accaatgaag gagtaggagc tatctacgga tctattatcg
    19801 cttctgggat ctttgttgtg ttagtttctg gtgtcttttc taaaattaaa aaactattcc
    19861 ctcctatagt aacaggaacg gttatcaccg ttattggttt gactttgatt cctgtagcaa
    19921 tcgagaaaat gggtggaggt aatgcaacag cagctgattt tggtgacaaa acaaatctgc
    19981 tacttgcatt tgtgacgatt ctcctaattg taggcgtgca aatgctggca aaagggttca
    20041 ttcgttcaat cgcggtattg attggtttag tcggaggaag catcttagct gctttcatgg
    20101 gaatgattga tctgagcgcg attggagatg cgccgttgtt ccatgttcca caaccctttt
    20161 attttggtaa accaactttc gacgtatggt cgattttact aatgatcatc atttccatgg
    20221 tcagcatggt agaatcaaca ggtgtatatt ttgcacttgg tgacattact gggaaaaatg
    20281 ttggagaaga agaattgaaa aagggatatc gtgcagaagg acttgccgtt atcttaggcg
    20341 gtattttcaa tacattccct tatactggct tttctcaaaa tgtcggattg gttcaacttt
    20401 cgggaatcaa aacaagaaaa cccatctatt tctctgcatt cttcttgatt gttttaggat
    20461 tattccctaa aatcggtgcg ttagcacaaa tcatccctga gccggtactt ggtggaggaa
    20521 tgttagtcat gttcgggatg gtggcagtcc aaggaatccg tatgctgttg gaagttgatt
    20581 tcagcaatga taaaaatcta ttgattgttg ctgtttctgt tggatttggg ctgggtttca
    20641 atgttacgcc gacattattc agtcaaatgc cgcaaacatt gcaaatgttc actggaaatg
    20701 gcatcgtaat gagtagcatt acggctatca tattgaattt gatctttaat ggattgaaaa
    20761 aagatgaaga aatattggaa gaagccttca agaagtaata gagcaaaaga aaggttgtga
    20821 aatcagcgtt ttgacctgat tgttagagaa acaaacggaa aaatagttcc tcgtattttg
    20881 ccgtttgttt gagctaatac cgagggtcag ctgattgaac accgttgaag gaagaggtcg
    20941 tgagcctgcc gttcatctcc gagtcacaag gaacaatttc aaaaaaaagc ttctcatgtt
    21001 tgttgaatat tgttccttgt gaccgaggag ttggcaggag aacaccgttt atccataaaa
    21061 aggaatgtga cctaactttt gtcacattcc ttttttttat ctttaataaa cacgaacaat
    21121 aaaatgtttt tctttgttaa cattcgaaat ttctttgaca tcaaaaaaag tgattgttaa
    21181 aatatgaatg tagaaaaact gggaggaaaa acaatgacag caaaaatctc tgtgattatg
    21241 gggagtactt cagattggga aacaatgaaa gaagcatgtc aaatattgga tgaattcggt
    21301 gtgtcttatg aaaaaaaggt cgtttctgct catcgaaccc cagatttgat gtttgaatat
    21361 gcacaaaacg ctcgaaaaaa aggaatcaaa atcattattg caggagcagg gggagccgcg
    21421 catctgccgg gtatggtcgc atcaaaaaca actttgccgg ttatcggtgt accggtccaa
    21481 tcacgaacat taaatggttt ggattcgctt ctttcgattg tccaaatgcc tggaggagta
    21541 cctgtagcta ctacagcaat cggaaaagcg ggagcaatta atgctggact acttgcgata
    21601 cagatgcttt ccatgtatga tttagaattg gaggctaaat tggctgaaag acgttcaatg
    21661 ttggctaaaa ctgttataga aagtagtgat caacttggtt aaacctttgt tgcctggttc
    21721 aacgatcggg atcgtcggtg gcggtcaatt aggtcgtatg atggcgatta gtgcaaaaga
    21781 aatgggcttt aaagtaggtg tgctggatcc tgtgagcgat tgtccagccg cacaagttgc
    21841 agattggcac attgaaagtg tctatgatga cacctttgcg ctgaaagagc ttgccagaag
    21901 aacagatgtc attacctatg aattcgaaaa cgtcagtgta gaggcgttaa atgcgatttt
    21961 acccatgtca tttattcctc aagggacaga cttgcttgcg attacgcaag accgcctgtt
    22021 agaaaaatct tttttggaaa cgaataacat cgtgattgct ccttatgcaa cgatcgtcag
    22081 tccgacggat atccaagatg cgattgacgg gatcggctat ccttgtgttt tgaaaaccac
    22141 tcgaggcggc tatgatggca aggggcagta tgttttgaaa agtcgggcgg atctagctcc
    22201 tgccatggac cttttaagag aaggaacctg tgttttagaa gcatggatcc cgtttgaaaa
    22261 agagatttcg atcatggtgg caggaaatgg tcaaggagat ttcacgactt ttccggtcgt
    22321 ggaaaacatc caccacaaca atattcttca tgaaacgatt gctccagccg cgattgatca
    22381 ggatgtgatc gaggaggctg agcgtattgc ccgtgtgatt gcagaagcag tgagcctttc
    22441 aggtgtttta ggggtagaaa tgtttttaac aaaaacaggc gggctatatg tgaatgaatt
    22501 agctcctcgt cctcacaatt ctggacatta ttctattgaa gcttgttcta tgagtcagtt
    22561 cgatgcccat attcgaggta tttgtggttg gccattagga gaaaaagtac gtttgataag
    22621 caatgcagta atggtcaatg ttttgggaga acaactgctg gaaagctatc gcttgattga
    22681 gaataagcca gactggcaat tccatttcta tggaaaaaaa caagcaaaaa aaggtcgcaa
    22741 gatgggacat atcactatct tgacagaaga catccagcaa acgctggaag aaatcaaaca
    22801 aacgaatatt tgggattaga ggagaaaaaa catgttagaa cgttatacac gccctgaaat
    22861 ggggaatatc tggacggaag agaacaaata ccgtgcgtgg ctcgaagtcg agattttagc
    22921 agatgaagct tgggcagaac ttggtgaaat cccgcaagaa gatgtgaaaa aaattcgtga
    22981 gcatgcatca tttgatatcg atcggatctt ggaaatcgaa aaattaacac gccatgatgt
    23041 cgttgcgttt acacgagcgg tttctgaaac attgggagaa gaaagaaaat gggtccatta
    23101 tggtctaaca agtacggatg tcgtagatac tgcttatggc tatctcatca agcaagcaaa
    23161 tgatatttta cgggaagact tgaaacgttt tacggaaatc attggcgaaa aagcaaaaga
    23221 acacaaatat acagtgatga tgggtcggac acacggtgtc catgctgaac caactacttt
    23281 tggattgaaa cttgccacat ggtattcaga aatgaaacgg aacatcgaac gatttgaaca
    23341 tgcggcaaaa ggagtagaag caggaaaaat ctcaggagca gtgggaacgt tcgcaaatat
    23401 cccgccattt attgaagagt atgtatgtaa acaattgggg atccgtccac aagaaatctc
    23461 tactcaagtt ctccctcggg atctacatgc tgaatatttc tcagcgatgg cgcttattgc
    23521 tacaagtatt gaacgttttg caacagagat acgcggattg caaaaatccg aaacacgtga
    23581 agtagaagaa ttttttgcga aaggtcaaaa aggttcttct gctatgccgc acaaaaggaa
    23641 tccgatcggt tcagaaaata tggctggtct agccagagtg gtgcgcggac acatggtcac
    23701 tgcctatgaa aatgtcacat tatggcatga aagagatatt tctcattctt cagcagaacg
    23761 aatcatcttg cctgatacca cgattttatt gaattacatg ttaaatcgtt ttggcaatat
    23821 cgttaaaaat ctaacggtct ttcctgaaaa catgaagcgg aatatgtctg caacatttgg
    23881 tttgatttat agccagcgcg ttatgctgaa attgatcgat aagggaatga caagagaaga
    23941 agcttatgat cttgttcagc caaaaactgc gtacgcttgg gacaaccaag tgcaattccg
    24001 cccgctgtta gaagaagatc caaccatcac atcggtatta tctaaagaag aaatagacga
    24061 tgcctttgat tatcatcatc atttgaaaaa cgttgacgtg atattcaaac gagtaggttt
    24121 ggaataaaga agagtgagtt gcaaaattca attaaaatag aatagcaaaa ataaccaaaa
    24181 aagaagcaga tccgttagcg gttctgcttc ttttagttta ttatattttc ttatcaataa
    24241 taggaacctg attttaaaag cggctacctc tttaccgtgc ctctttacat acaaaaaata
    24301 gaggaattaa gcgtaaatgg cttggctatt ataactaaaa tgctggttat ggagatgttg
    24361 cagcaagttt tcgagaaaag cgtattccat ctcttgtcca ttgaataaga tctggatacg
    24421 ataatgattt ttgaaacgct tctgttcatg aatctgactg attgaaagtt cgcctttgtg
    24481 ttctgtctga taaagaaaag tccttttacg gcattcagca cagcgcttgg ttgctcggcg
    24541 gatttttcgg aatgtataaa aactagtatc tttattgcat aaataaacgt ctttgatcga
    24601 cagcaaatca ttatatagac aggaacgttc ttcagctgtt aattctgata aaaaaagctg
    24661 accttgtttt attgcatctt ccatcggcaa gtgcctcctc gaacccatta tccaaatttt
    24721 tagttaattc taatatacca tcattaagta taaatgtaaa cgcttgttga tggtataaga
    24781 ttttcgtttc tgataaaaca cgaacattaa aagaatctaa tgccttaaat gtacatattt
    24841 ttgttgattt ataaaaagat gattgctaaa atttaaagtg aaaaaacgaa caaaaaacga
    24901 tgtatttgct tttaatgtaa ataaaaagga gagacgtaca tggagaagaa agaacttttg
    24961 tatgaaggaa aagccaaaaa aatatatctt acttctgatg agaacttgat ttggatagaa
    25021 tatttagatc aagcaactgc gttgaatggc gcgaggaaag accagataag tggaaaagga
    25081 gaattgaata atcaaatcac aagtgcaatt ttccgttatc tgactcaaag aggaataaaa
    25141 aatcatttta ttgaacaatt gtctaaaacc gaacaattag caaaaaaagt acaaattatc
    25201 cctctggaag tggttatccg aaatattgca gcaggaagtt tctcaaaacg tctaggtgtt
    25261 cccgaaggta aagaattcat caaaccaatc attgaattct actataagga tgaccagttg
    25321 gatgatccat ttatcaatga agagcatatc tatttcttac aacttgcaaa gccggaagaa
    25381 atcagtgagc tgaaagccca agcgttggct attaatgaaa ttttgaccga attatttgct
    25441 aaggtcggtt tggttttagt agatttcaag ctagaatttg gccggtcgaa tggacaaatt
    25501 ttgcttgcgg atgaagtaac accggatact tgccgattat gggatgaacg tacgaatgaa
    25561 catatggaca aagacgttta ccgcagagat ctaggtgatt tgatcccagt ctatcaagaa
    25621 gtatataacc gtctatcgga actaactgaa gaaaaggagc gagtatgatg tatttcgtaa
    25681 aagtatatgt aacctataaa gattcagtgt tagatcctca aggggaggca gtaaaaaaag
    25741 cagtccatcg tatgggatat gaaacaatcg aagatatccg aataggaaaa tactttgaga
    25801 tacaacttgc tgatgcagaa gaaccaatcg atacagtgat tgaaacgatt tgtgacaagc
    25861 tgcttgcaaa tgtaaatatg gaaacatacc gatatgaaat caaaaaaatg gaggaagtat
    25921 aacatgaaat ttgcggtcat cgtttttcca ggttcaaatt gtgacgcaga tatgttatgg
    25981 gcagttcgcg agatcatggg cgctgatgcc gaatttgtac ggcatgatga gtcctcttta
    26041 gaaggatttg atggggtttt actgccggga ggattctcct atggtgacta tttgagatgc
    26101 ggtgcgattg ctcggttttc tacaatcatg gaagaagtga ttcgttttgc tgaagaaggg
    26161 aaaccagtat tcggtacatg caatggattc cagatattga cagaagcagg acttttgcca
    26221 ggtgtactga gacgaaatga gtctttgcat tttatttgca aaactgtacc attgaaagtc
    26281 aaccccaaga cggcctttac ttcagagtat gaagccgacg aaataatcta tcttccagtt
    26341 gctcatgggg aaggaaatta tttctgtgac gaagaaacac ttcaagaact aaaaaaaaat
    26401 aatcagattg cctttactta taatgacaac atcaacggca gcgtggaaaa cattgcaggg
    26461 attacgaaca aagcagggaa tgtgttagga atgatgcctc atccagaacg tgcagtagaa
    26521 gacttgctag gatcagaaga tgggaaacgg ttctttgctt ccattttaaa aaacttcgga
    26581 aaggtgaccg tatagatgaa aacattgaaa gaaccgacag ctgaagagat caagaaaaaa
    26641 agaatctatg ccgaatgggg attgactgat gaagaatatc gaatgatcga agaagatatc
    26701 ttaggaagaa tgcctaatta tacggaaact ggactgtttt ctgttatgtg gagcgaacat
    26761 tgttcctata aaaattctaa accggttcta cgcaaatttc ctactagtgg acctcatgtg
    26821 ttgcaaggcc ctggagaagg cgcaggcatc gtcgacatcg gtgatggact agcagttgtc
    26881 ttcaaagcag aaagtcacaa tcatccttca gccgtggagc cttatgaagg agctgcgaca
    26941 ggagttggcg gaatcatcag agatattttc agcatggggg ctcgtccaat tgcgttgcta
    27001 gattcattga ggttcggcga attagataat ccaagaacga aatatttact agaagaagta
    27061 gttgcaggta tcggcggata cggcaattgt atcggcatac cgactgtagg cggcgaaatt
    27121 gcatttgatc cttgttatga aggaaaccca ttagtcaatg caatgtgcgt aggtttgatt
    27181 gaacacaaac atatccagaa agggcaagcc gctggcgtcg gtaattcgat catgtatgta
    27241 ggtgcaaaaa caggtcgcga cggtatccac ggagcaactt ttgcctcaga agaatttaat
    27301 caagaagaag aacagcaacg ttctgctgta caagtaggcg atccttttat ggaaaagctg
    27361 ctgcttgaag cgtgtttgga attaatcttg catcattcgg attctctaat aggtatacag
    27421 gatatgggag cagcaggact tgtttcatct agtgcggaaa tggcttcaaa agctggctca
    27481 ggacttatat tgacattaga tgaagtccca caaagagaaa ctgggatgac accttatgaa
    27541 atgatgttat cggaatcaca agaacggatg ttgatttgtg ttaaatcagg agaggaagaa
    27601 aaaatccaag aactatttca gaagtatgat ctagatgcag tcactatcgg taaagtaaca
    27661 gacgacgggc aatatcggct atatcatcaa ggagaagaag tagcaaatct gccagtcgat
    27721 gcattagctg aagatgcacc agtttatcat aaagaaatga aagaaccagc tcgaatcgta
    27781 gaatttcagc agttagctcc ttatcagcca gttatcgaag aacctggaca agtattgctt
    27841 gatctgctgc agcaaccgac gattgcttca aaacgttcaa tctacgaaac ttatgattca
    27901 caagtacaaa ccaatacagt tgtccgtcca ggaagcgatg ctgctgtgat gagggttaga
    27961 gggacgaata aagcgttagc tatgaccaca gactgcaacg cgcgctatct gtatttggat
    28021 ccaaaaatcg gaggacaaat agcagtggca gaagctgcta gaaatattat tgctagcggt
    28081 ggtaagccct tggcgatcac cgactgcctg aactatggtt ctcctgataa accagaagtt
    28141 ttttgggaat tatcgacttc agctgacgga attgctgctg cgtgtgaaac gttaggaact
    28201 cctgttattt caggaaatgt ctctttatat aatgaaacgg atggtcaagc aatctatcca
    28261 acaccaatga ttggtatggt cggattgatt gaggatcata aacatatcac tactcaggaa
    28321 ttcaaaaaat caggggatct aatctatata ttaggtaaga cgtttgcaga ttttgatggc
    28381 agtgaattac aaaagatgca gcttggaaga atcgaaggtg tgatccgaaa ctttgatcta
    28441 tccattgaaa agagaaacca agagttagta ttgacagcca tccaaaacgg attgattgaa
    28501 agtgctcatg actgttcaga aggtggcttg gcaattgcac tggcagaatc agctttcaaa
    28561 catcagctag ggatatctgt acagtttgaa ttgtcctctg ctcaattatt tgcagaaact
    28621 caatcaagat ttgtgttgac agtcgcaccg gaaaataaga cacgattcga agaaatgatg
    28681 ggagatgctg ctgttttagc aggtaaggtg acggatgaag cgataatcga aatttcagca
    28741 actgacggtc agatcaaaat agaaactgca gtagcaagaa agtgctggga ggatgcaatc
    28801 gtatgtctta tgaagtgaag agtttaaatg aagaatgcgg gatcttcggt gtttggggtc
    28861 atccagacgc cgctagtgtg gcatacttcg ggctccatag tcttcagcat cgaggacaag
    28921 aaggtgcagg tatcgtgtcc aatgatcgag gaaagcttaa ggggcatcga gatttggggc
    28981 tgctttctga ggtattcaaa gatcaaagaa aattgcagca gttaacagga gaagctgcaa
    29041 tcggacatgt acgttatgca acagcaggca atggaagtgt ggacaatatt cagccttttc
    29101 tattcaaatt tcatgatcag tcgatcggct tagcgcataa tggtaacttg atcaatgctc
    29161 gttcccttag aaaagagtta gaggaaaatg gggcgatctt ccattctaac tccgatacgg
    29221 agatattgat gcatttgatc cgacgaagtg aagaaacaga ttttttaaat aaattaaaaa
    29281 gtgctttgaa tgaagtcaaa ggtggctttg cctatttatt aatgacagaa acggcaatga
    29341 ttgccgcttt ggacccaaat ggttttcgtc cattagcaat cggacaaatg aaaaacggag
    29401 catacgtgat tgcctcggaa acttgtgcat tagaagttat tggggcacgt tttataagag
    29461 atgtccagcc tggtgagata gtgatcatca atgacgaagg aatccagatt gattgcttta
    29521 cgaaggacac gcagctttct atttgttcga tggaatatat ctattttgcc agaccagatt
    29581 caaacatcgc agggatcaat gtgcatactg cacggaaaaa tatgggacgg aatttagcga
    29641 aagaatcgcc agtaaaagca gatatggtcg ttggcgtacc taattcttct ttgtcagccg
    29701 caagcggtta tgcggaagct agtggaatcc cttatgaaat cggattagta aaaaatcaat
    29761 acattgcccg aacatttatc cagccaacgc ctgagctaag agagcaaggt gttcgaatga
    29821 aattatctgc tgtacgagga gtagtggaag gtaaaaaggt gattatggtc gatgattcaa
    29881 ttgttcgggg tacgacaagc agacggatcg tccatctttt gaaagaagca ggggcaaaag
    29941 aagtccatgt gaggattgct tctcctcctt tgaaatatcc atgtttttac gggattgata
    30001 ttcaaacgcg taaagaactc attgcggcaa atcacacgat tgatgaaatc aaagaatgta
    30061 tcggtgcaga ttctttaggt tttttaagtg aagagggtct gatcgaatcg atcggtctgg
    30121 aaaaagatgc tccgtattca ggattgtgta tggcttattt caacggagat tatccgacgc
    30181 cgttatatga ctatgaagaa aaatatcagg aatcactaaa agaaaaagta tcgttctttt
    30241 aaaagcagac caagaaggga gtatatgaat tcaatggcaa atgcatacgc aaaagctggc
    30301 gtagatgtcg aagctggata tgaagtagta gaacggatca agaagcatgt caaaaaaacg
    30361 gaacgtttag gtatgatggg cgctatagga ggattcggcg gttgttttga tttatcggtc
    30421 tttcaattaa aagagccagt ccttgtctcg gggaccgatg gcgtggggac gaaattagca
    30481 gtggcaatcg aagcagacaa acacgataca atcgggatcg actgcgtagc gatgtgtgtc
    30541 aatgatatct tagcacaagg cgcagagccg ttatatttct tagactactt agcaacgggg
    30601 aaaaatgatc cgttacgttt ggaaaatgta gtaaaaggtg tagcagatgg atgtgttcaa
    30661 ggaaatatgg cgctgattgg cggagaaaca gctgaaatgc ctggtatgta ctcaggtaat
    30721 gattatgatc tagccggatt tgctgtaggg atagctgaaa aatctcaatt attgacagga
    30781 gaaacgatca acccaggaga tgtgttgctt ggaatagcat ctagcgggat tcattcaaat
    30841 gggtactctc ttgttcgcaa aattttcttt gagcagcagc agttttcttt atcatcaaaa
    30901 ctgccagaat tgaaaaaaac acttggcgaa gaattgcttg agccaacgaa aatctatgtt
    30961 tcttccttgc ttccgctgat caaagaaaag aaaataaaag gagctgcaca tatcactggt
    31021 ggagggtttg tagaaaatat cccgcgaatg ttaccagaat ctatggctgc acaaatcaaa
    31081 cttggctcat ggccgattct tccaatattc ggctgtttac aaaaatatgg tgaaattcct
    31141 gagatggaga tgtatgaaat cttcaatatg ggcatcggta tggtcctggc agtcgaagaa
    31201 tcgaaagtaa aagaaatagt acacgaaatt gagcaagctg gcgaaaaagt ttatgaaatc
    31261 gggaaagtga tcgccaaaga aaaacatcgt gtggtgttta taggagaaga acgatgagaa
    31321 tcgctgtttt tgcttctgga aacggaagca actttcaagc gctagccgat tatctatcga
    31381 aaaaaggatt ggaatcttcg attgactggt tgttttgtga tcagcctgaa gcatatgttt
    31441 tgaaacgtgc aactgcgttg agtgtaccgg cagattgttt ttcacctaaa gaatttgatt
    31501 caaaaaaaga gtatgaagaa gcaattttgc ataaattgaa agaaaaaaag atcgatttga
    31561 tcgtattagc tggatatatg cgaatcattg gaccggtatt gctgaaaaat tatgataaaa
    31621 gaatcatcaa tatccatccg tctcttttac ctgccttccc tggtttgcat ggcatacgtg
    31681 atgcctttga agctggagta aaagaaacgg gtgtcacaat tcattatatc gaccaaggtg
    31741 tagatactgg accaatcatc cggcaggaaa aagtgagaat tgaacaggag gacacgttcg
    31801 attctttaga agaaaaaatc catagagtag agcatcgaat ctatccagaa gtgattagtg
    31861 aaattattga aaatggaggc tatctgaaat gacaagagca ttgatcagtg tatcagataa
    31921 aactgggatt gtagcattcg cccaaggttt gattgaacaa ggagtagaaa tcatttcaac
    31981 aggaggaaca aagcatgcgt tggataaagc tgggatcaaa acgctttcga tcgaagaagt
    32041 gacagggttt cctgaaatga tggatggccg tgtcaaaaca cttcatccta aaatccatgg
    32101 tggtctttta ggaagacgcg atctccctag ccatatggag gcaatggaaa cggaaaatat
    32161 ccaaccaatc gactttgttt gtgtcaattt atatcctttc aaagaaacga ttatgaaacc
    32221 agatgtcgaa atagcagaag ctattgaaaa cattgatatc ggtggtccta gtatgctccg
    32281 tagtgcagca aaaaaccatg aatttgtcac ctctgttgtt gatccatctg actatgaaga
    32341 agtactttca gaattacgtc agtatgggca tacttcactt tctttcagac aaaaactagc
    32401 ggcaaaagtc tttcgtcata ctgcggcata tgatgcactg atcgctcaat acttaacgga
    32461 ttgggtggaa gaaaaagaac cggaaaaatt gacacttacg tatgaacgaa aacaaacgct
    32521 tcgttacggt gaaaatagcc atcaagccgc tgccttttat cagtccgctc ttctggaaaa
    32581 atattcgatc gcagcagcaa aacaactcca tgggaaagaa ctttcttata ataatatccg
    32641 agatgcagat gctgcgctac ggatcatgaa ggaatatgac gagccaacgg tagtcgcctt
    32701 gaaacacatg aatccttgtg gtattgggac agcatctacg attttagaag cgtgggaagc
    32761 agcgtatgaa gcagatcctg tttcaatctt tggtgggatc atcgttttga atcgagaagt
    32821 agatctgcca acagcagaac agatgcataa gctgtttcta gaaatcatca ttgccccttc
    32881 ttatacacaa gaagctttgg aattactgca aaaaaagaaa aacatccgat tactgacagt
    32941 agactttgcg caggaagaaa atcaaaatcg agaagaaacg gtctcagtct taggtggact
    33001 tcttgtacaa gatcaagatc tggcaataga aaatgaagaa gagtggaaag tcgtgacaaa
    33061 acgtaagccg actccagcag aagcaaaagc attagcgttt gcttggagag ctgtcaaaca
    33121 tgtgaaatct aatgcgatcg tactggcaaa cgaacgtcag acagtaggaa tcggagccgg
    33181 gcagatgaat cgagtcggtt cagtaaaaat tgcgattgaa caagcgcaag agaaaatgga
    33241 aggtgcagtt ttagctagcg atgcttattt tccaatggat gattcggttg aatatgcagc
    33301 caaacatggt ataaaagcaa tcattcagcc aggaggaagc atcaaagacc aagattctat
    33361 tgatatggcg aataaatacg atctagcaat ggtctttact gatgttcggc attttagaca
    33421 ttagagagga gtcggataaa tgaacatttt ggtgatcggt gcaggtggtc gtgaacatgc
    33481 aataagtaaa aaacttttag ccagtccgaa ggtggatacg gtgtattgtg cgccaggaaa
    33541 tccggggatg acaaaagatg gtatcaattg tgtcgctatc agtgagcgag atcattcagc
    33601 gttaatccat tttgttaaga aagaggctat tgattggagt atcgttggtc ctgaagttcc
    33661 tttgttaaat gggatcgtcg atgattttat ggcggaagga ttgaaaatct tcggtccgac
    33721 aaaagcagca gctctgatcg aaggttcgaa aagttttgct aaacaattaa tggatactta
    33781 tcaaatcccg acagctaaat ccagaagttt tgaatgttac gaaaaagcag cagcgtatat
    33841 caaagaaaat ggtgcgccaa tcgtagtgaa agcggacggc ttagcagctg ggaaaggtgt
    33901 agtcgtggct accacagtga aggaagcgct ggatgcggca gaacaaatgt tgaaccagca
    33961 tcgatttggg gatagtagca aaaaaatcgt cgtagaagag tttttggcag gagaagaatt
    34021 ctcccttttg gcgtttgtcc gtaataccaa ggtgtatccg atggtcattt cgcaagatca
    34081 taagcgggca tttgataacg ataaagggcc aaatacaggc ggaatgggtg cttattcacc
    34141 agtaccgcaa atttcaaaaa agatgattga aaaagctgtg gaagaagttt taaaaccagc
    34201 ggctttggga atgaaagaac taggacgctc tttcacgggt gttttatatg cgggtttgat
    34261 tgctacgaag gaaggaccaa aagtgatcga attcaatgcg cgtttcggtg atcctgaaac
    34321 gcaagtcgtt ctttctcggt tgaagagtga ctttgcgcaa gtaatcgatg atttattaga
    34381 gaatcgtaca gtagagttaa agtggcagca agaaggatac aatgtaggcg ttgtggttgc
    34441 agctgccggt taccccgaag aatatgagac aggaatggtt ctaccagatt ttctggaaga
    34501 agagctttct gtttactatg ctggagtttc ctcaaataac ggcaaactag ttggagcagg
    34561 aggacgtctt tatttagtag aagcatacgg tgagacgatc aaagaagcac agaaaaaaat
    34621 ttacaccgcg ttaatggata aaacgacaga tggaacattt tatcgtacag atattggaga
    34681 aaaagctgcc aatagcgaac tgatcgtgaa gtaaatcagc tgcttccatt tataaaaaat
    34741 acaacaaaca taatcggaag cgccgatttt agtgaagcct tttcataaag agtgtggtac
    34801 acttttgttg tgtatataaa taaggaggag ttcagatgaa aaaaattcaa ttaggtactt
    34861 ctgatcagaa agcagctgca gtgatcttag gctgtatgcg tatcaacaat gcggaagatc
    34921 cagtaaaagt gattgagaca gcttatgaaa acggcattga tttttttgac catgcagata
    34981 tttatggaaa cggtgaatgt gaagaaatct ttgcagatgc tctagcaaaa acatcaatca
    35041 aacgagaaga tctttttatt caaacaaaat gtggaatcgt tccaggtgtg atgtttgatt
    35101 tttctaaaaa acatatcatt gaatctgtag aaaaaagttt gacccgtctg aaaatggatt
    35161 atgtggatgc tttacttctt catcgtccag atacattggt agaaccagag gaagtagctg
    35221 aagcgtttga tgaattggaa cggtcaggaa aagttcgtta ttttggcgtc agcaatcaaa
    35281 aaccaatgca aatcgaattg ctgaaaaaat atgttcgtca accattagta gctaatcagc
    35341 tgcaatttgg cttgaaacat actggaatga tcgatcaagg gattcatgtc aatatgacag
    35401 atgaagcaag tatcgatcat gacggtagtg tacttgatta ttcccgattg catgatatga
    35461 cgatccaagc atggtcacca taccagtatg gattttttga aggtgtattt atcgggaacg
    35521 aaaaattccc tgaattaaac caaacattag aagaactagc agctaaatat caaacgacac
    35581 caactggctt ggcttctgct tggattttac gccatccagc caatatgcaa gtgatcgccg
    35641 gtacgatgaa cgtagggcga atcaaggaaa tcgctcaagc ttcagaaatt aatatgtctc
    35701 gggaagattg gtacgaattg taccgtgctg ctggaaacat tttaccttaa agattgtcat
    35761 aagcaggtca aaagggctat aaattaaaaa gacagaataa cttgaaagct gttttcagct
    35821 tcgagatatt ctgtcttttt ttattgcaaa tggaaagagt atcattgtac ggatttcgtt
    35881 tattagttat ttttgttttt aaggaaaagc tgtgtccgat attcttttgg agaaatccct
    35941 tgttttttct taaataaata actgaaatag ttagggtcat tataaccaat ttcaaaagca
    36001 atatctgaaa tacgatagtc tgattgctgc aataattttt ttgctaattc gattctttgt
    36061 tctgtcagat aatcgatgaa tgtttggtta aacgattgag aaaaaatcgt actgaaatga
    36121 gagggactta atgcaacttg ttgagcgacc caagttaagg acatatctgg atcggtaaaa
    36181 ttttctttga taaaatccaa tgcatggttc aaaattggct gatatttgtt ccttgaaggc
    36241 tgtgagggca gagcagttaa gaaagaaatg aacatataaa ctgtcgaacg gtaaagcgag
    36301 tcgtcggcgc tgattgctaa gcgttgactg gtggatgtgc aatgaaccat ttcttgcggg
    36361 attttctttt ctttcaggca gacatgctgg agtagcttag tcaagacaaa taaacgatat
    36421 aatcgtgttc gagttggtgt gccttgtggt ttcgtcaagt gttcgatgta cttagatact
    36481 tcgtttttcg ataatgaaga caaatcaagt gagaggtcaa agtaaaagac agaatcaact
    36541 ggaagtttcg cttcttgaat caaatcctca tagctgataa tttgttcttt aagggaactg
    36601 gcggtttcaa gtatcatctg cgtgatctca aaagatgcag gtaattcgct gattctttct
    36661 gcgacaggac caatggcgac agaaaaatta tttttttgtc ccttttctaa ttcatggacc
    36721 aacgtttggg ctacctgata actggtctcg atcacatttt cttcaagaga atcaactatt
    36781 aaaaatttga tgaatcgaga ggaaacagca gagaagatca cttgttgatt ctccctaaat
    36841 aaaaacttca aataatcact gagatgagcg taatcttcaa agtctgtact gacttggttt
    36901 gctgctaata atacggtcat ttttttccct gctaaagagc gattgaaaga ttcagcaagt
    36961 ttcaatgttt cactgatcgt aagtgagcct ttgaacaaac cgttcaagaa atgatttttt
    37021 ttcaattcga aaacaagatc agaagaagtg tgcgtttctt tttgctgcaa atctaaagca
    37081 gttactgctt tttctattgc ttgtttcaat tcgctacttt taatcggttt aagcagataa
    37141 tcatctgcct gtacctggat tgctcctttc atataatcga aatcgtcgaa tccactaata
    37201 aatatgagac gagtccaagg aagtagtttc cttgcttctt ttgaaaaagt caacccgtcc
    37261 atgaaaggca tttggatatc agtcagaatg atgtcgggct gtaagtcgat aattgaagac
    37321 agtgccatct caccatctcc agcttcgccg acataagtga ttggataata agaaccaagg
    37381 acagttattt gttcccgcaa gttattgcga atgaggtatt cgtcttcgat gataaaaact
    37441 ttatacatgt ttgtttcctc caattgtttt gggagataga gggatcatca gtgtgacagt
    37501 tgttccttct cggtatttgc tgtcaatcgt gataggtttt tgatcatttc cgtaataaag
    37561 aaggagacgc ttgtttacgt tgtaaagtcc gtagccgata ctgaaatctg aatcgatccc
    37621 tttggctaac tctttacgta tttctgccag tttttctgca gggatgccaa tcccgttgtc
    37681 tataactttg aattggatca tctcatcaat tttgcatgtg gtaatacgaa taaatccttt
    37741 gtgacggacg tacttcgttc catggtatac agcattttca atcaatggct gcaagatcat
    37801 ttttaaaata gaaacaggaa aaagtgtttc tggtatatcg atcttatagt caagcatatg
    37861 gccgtatctt atttttaaga tgactagata atcattgata tggctaattt ctttttcaag
    37921 aggaatccag tcttgtcctt tgcttaaaga cgtacgaaaa aagccggaaa gtgcatgggt
    37981 catagtcaga gcttcttcaa agcagtcttg ttcgatcaaa gaaataatgg catccaaact
    38041 gttataaata aaatggggag taatctgagc ttgcaataca cgaacttcac tttgtgctaa
    38101 atggtattgt ttcaaagcgt tctcccgtaa agactggttt agatcttccg ccattttatt
    38161 catgctagcg gtaagtgttt gtaattccag tgtttccggc agggttaaac gaaagccaag
    38221 gttccctgaa gaaagttgtt ctgacatctc gatcagctga ttgatcggtt cttggacctt
    38281 tctctctaaa aagcgacgat tctttttcgc atagaaaaaa atggtactaa gaactccaag
    38341 ttccactatt gttaatagaa tgagcgagcg gacaagtgtc gtattttttt tgcttgctaa
    38401 gtcgatctcc acacgaacaa aatcttgtaa gatatctgac agcagttgag tgacagaatc
    38461 tacctgattg atgatctctt cattggtatc cataaaatct tttgccaaga tattattgat
    38521 cagctcgttt tgataatctt ccagtgtatc gatcgtacgt agcgatacat ctaacgtact
    38581 aatttcttta agtgtatttg tattattttt gatctctcga atatcattcc taagttcttc
    38641 taggatattt tcctcattga actcatctac ggttacttgg ccagaaatca agtcccacat
    38701 actttccaaa actttttgat caaccttcaa agcaattgca tctgcttttt ggatatttgc
    38761 gatcgtctgt tgataaatca aaagctgttg cgaatataac agtatgctca gtagcaaagg
    38821 gataacagca aatagaagca tggctttgtt tgcttgggca aaaatctgtt ttatgcttaa
    38881 attttttgtc atgatacttc tccagtcaat aatttctggt tgggatgtta gctatattct
    38941 gctgggaaaa gacagtctcg gaaataaaaa tatctttagg taatgttttt cctgtttgaa
    39001 tatttccaaa ataacgagta acggtattgg ctacatacca gccgacatca ggtttacact
    39061 cgactacaca attgacgatt cctgagcgta gcttctcgat catatcttct tgtccatcaa
    39121 tagttacaat gatcaaatct tctccaggtt tgattgatgt ttcttttatc gcagctaaag
    39181 caccgtgagt catttcatca ctatggctgt ataatacatc gatttcggat aaatcatttg
    39241 tttctaaata tcgtttcatc tggtcttttc ctttcatccg aataaaatca ccgacaattc
    39301 ggtgaacaat agtcatcgga ggtttatggt cgatggttcc atcttttttt agggttggtt
    39361 tacgattgat tgattccaaa aatccttcgg agcgtagctt ggtcggtgtg gagttctctg
    39421 aaccagcaag ttctaggatt ctgatttcct gtttctttga atttgtgaag tgattgctga
    39481 caaataaacc cgcccgattt ccttctgctt tgaaactggg gccaatgtgg gtgacgaaaa
    39541 gctcgggatc attcgtttga atatgtctgt cgacaagtat gacagggatc cctgctcgct
    39601 ttgcttcttt taatacagag tcccacccgg attcttgcaa aggagtaaaa atgatcatat
    39661 ccactttata ggcaatgaac gtccgtatat cttggatttg ccgttcctga ttcatgtagc
    39721 catttcggta gagaacttgg taatcttctt tttcaagcgc agtgataatt gattcagtat
    39781 gctttttccg ccagctactc tccgttcctg attgcgaaaa accaacgact agtgggtcag
    39841 gtgcttcctt tgtattaggt gtacacccca tcatttggta agcgattaca acaagggcta
    39901 aaaaaaataa aacacgtttc actttaaatc actccatctg gatttgttag tactatctta
    39961 tcagataaaa gggaaaatca aagtcaaaag gaatcaatcg aaaaaaatcc aagaaactta
    40021 aaaaaatcca agacaaaaaa agtacaccta aaaaatttaa agtaaatccc ataaaaaaat
    40081 caatgttaac gctttcttta ttagctatac tcggtgtatc aattgaaatg ggggataaaa
    40141 aatgaaaaac aaatttagaa agattgttgg gactatcgct attttgaccg caagcattct
    40201 attaagtgcg tgtggcaatt caggatctgc agatgatagt acggggtatg taggaatcgc
    40261 tatgccgacc aaatcagcag aaagatggat cgctgatggg aacaacatgg tctcggaatt
    40321 agaaaaactg ggttataaaa cagatcttca atatggagaa gataaagtag aaaatcaagt
    40381 agcacaaata gaaaatatga ttacaaaagg ggtagataca cttgtgattg cttctatcga
    40441 tggttcggct ttaactgatg tgttagctaa agcaaaagaa gcagatatca aggtgatcgc
    40501 ctatgatcgt ttactgatga attcagaaaa tgtcgattat tacgcgactt ttgataattt
    40561 tggagtaggt gtatcgcaag cagcttatat tgaagagcac ttaggattga aagaaggaaa
    40621 aggaccattc acgattgaat tatttggtgg ctcgcctgac gacaacaacg cactaatcaa
    40681 ttacaacgga gtgatgtctg ttttacaacc atatatggac aacggtcagt tggtcgtgcc
    40741 atctggacag acgagtttca gtcaaatcgc tacgcttcgc tgggatggtt ctacggcgca
    40801 agcaaggatg gataatctgt taagcgcaaa ttatactgac caaacattgg atgctgtttt
    40861 gtcgccatat gatccaataa gtttaggaat catttcgtca ttaaaaggcg tggggtatgg
    40921 gagtgaaagt aaacctttac ctgtgattac tggacaagat gcgacagttg ctggcgttaa
    40981 atcgatcatt gccggggaac aaacacaaac gatctttaaa gacacacgta tcttagcaaa
    41041 aaatacgatt gaaatgatca aagcaatcag tgatggagaa gaggttccgg tcaatgatac
    41101 tgaaacttat gataatgggg tgaaaactgt ccctacgtat ttagcaaata cagtatctgt
    41161 cgataaagat aattatcaag cagagctgat cgacaccgat tattataaag aatccgatct
    41221 gaaaaattaa gaggaaccaa acaaggaact aaagagatct aagtcagaga gaggataaga
    41281 attatggcgg attgtatttt aaaaatggca gatatcacca aaaaattttc tggaatccga
    41341 gcgttagatt gcgtgaatct gatgattgaa cgtggggaaa tccatgcatt gtgcggagaa
    41401 aacggagcgg gaaaatcaac attgatgaat gtcttgagcg gcttgtatcc atatggctcc
    41461 tatgacgggg aaatctttta tgatggaaag ctgtgtcaat ttaaagattt gaaagatagt
    41521 gaagaaaaag gcatcgtcat cattcatcaa gaattagcac taagtcctta tctttcaata
    41581 aaagagaata tttttctcgg aaatgaacaa gcagaaagag gcgtgattga ttgggaactg
    41641 acagaaaaga aaacatatga actgctgaat aaagtcggtt tgtctatcga cccgaatctt
    41701 ctagtatccc agattggcgt agggcaacag caactagttg aaatagctaa agcattatca
    41761 aaatccgtcc gtctgttgat tttggatgag cctaccgctg cattgaatga agaagaaagc
    41821 gcgaatttgc tgagattgat ccgagagttg aaagagcaag gtgtaacctc catcattatt
    41881 tcacataagc tgaatgaaat cgtggatatc gcagatcgaa tcaccatttt acgggatgga
    41941 cagacgattg agacactaga aaatgaaatg atcagcgaag agcatattat tcgcggaatg
    42001 gtgggcagag atttagttga tcgttatcct gaaagaaaac cggatattgg agaagtttat
    42061 tttaaagtag aagactggac ggtctatcac cctcttgatc acgagcgaat cataaacgac
    42121 cacatcaact tgcatttgaa aaaaggagag attgtaggaa tagctggact gatgggagcg
    42181 ggcagaactg aattcgctat gagtctattt ggacattctt atggaagcaa gatatccgga
    42241 cgtatattaa aggaaggggc agagatatca gttaagaccg ttccttcagc cattgcaaac
    42301 ggactcgctt atgtctcgga ggaccgaaaa tctttaggac tgaatctgct gatggatatt
    42361 cgggaaaacg tgacgctgag cagtttggat aaaataagtc aaaaaggagt attagataaa
    42421 gaaaaagaag taactgaggc agaaaatttc cggaaaaaga tgcgtataaa aacaaactcc
    42481 atccatcaaa ttgtcagtag tcttagtggt gggaatcaac aaaaagtcgt tttatccaag
    42541 tggctgatga cacaacccga tattcttttt ttggatgagc caacccgtgg gatagatgtt
    42601 ggggcaaaat atgagatcta cacgattatc gaagaaatgg cagcaaatgg caaagctgtc
    42661 tgtcttatct cttctgaact tcctgaaata ttagggatgt gtgatcgaat ctatacgatg
    42721 aacgaaggac gtattacagg agaagtctcg cgagaagatg cagatcagga agtcttgatg
    42781 aaattaatga cgaaagaaga ggtgggttaa gttggaacag gcaaaaaatc ttacggataa
    42841 aaaagagaaa aaactaaatt tgaaaagtag agcagctgat ctttttggtc gctacagcat
    42901 ggtgatcatt ttagcgggac tacttattgc gtttcaattg atgacggatg gtattttctg
    42961 gcgtccattg aatataacta accttgttct gcaaaatagc catatattag tactagctgc
    43021 agggatgtta ttagttgtgc tcttaggtca tgtggatttg tcggtagggt cagtgatggc
    43081 gtttgttggt gcaattgcgg gcatgatgat ggtcaatcgc caaatgaacc cgtggatgac
    43141 agttatcgca tgtcttgcag taggcgggct gatcggcgca tggcaaggtt tttgggtagc
    43201 ttatgcaggg ataccggcgt ttatcgtgac tttagcagga ttgctgatgt ttcgtggact
    43261 gacacaagtt gttctaggag gccaatctct agcacctttt ccagctgttt tccaaaaaat
    43321 gtctacgggt tatttaccag acttaagcga aggaagcagc cttcacttct tgacattgat
    43381 tttaggaatg atcatcacga tcgtgttagt tgttggtcaa tggcgaacaa gaaatcgtcg
    43441 gaaaaatcat ttatttgaag tggaatctcc aacagctttc ttggtaaagg cggtatttac
    43501 agcagtcgtt gtactaggaa taacttatat ctttgcctct tatcaagggt atccgattat
    43561 tttgatcatt cttggtttga tcgttgcagc atatgggttt ttgacaaata aaacagtagc
    43621 aggtcgacag atttatgcga cgggcggaaa tcgaaaagcg gctgaactat cagggatcaa
    43681 aacaaagcga atcacgttct gggtattcgt caacatggga gtcatggcag ctttagctgg
    43741 attagtttta gctgctcgat tgaatgcggc aacacctcaa gcaggtacat cgatggaact
    43801 ggatgcaatg gcggcagtat attttggtgg tgcttcgact tccggcggca ttggaacaat
    43861 catgggtgcg attgtcggtg gcttggtcat gggtgtattg aacaatggca tgtcgatttt
    43921 aggcgtcggg gtagactggc agcaggcaat caaaggattg atcttgcttt tagccgttgt
    43981 gctagacttg tataataaga aaaaacgaac aacgtaggag aacgccggtt attcagaaaa
    44041 aagactgtga caagacattt gtcacagtct ttttttcgct aaaagcgaac attcattgtt
    44101 tcgtttgtat agactaaaaa taatatatgt ttttttacca ttcgtataaa ttctcttttt
    44161 gctcttgatt tttttgct
//
LOCUS       DAZKPE010000017        43754 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000017 DAZKPE010000000
VERSION     DAZKPE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.017"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(114..458)
                     /locus_tag="ACG930_001025"
     CDS             complement(114..458)
                     /locus_tag="ACG930_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFQ0518199.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(451..885)
                     /locus_tag="ACG930_001026"
     CDS             complement(451..885)
                     /locus_tag="ACG930_001026"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFQ0518200.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            1023..1760
                     /locus_tag="ACG930_001027"
     CDS             1023..1760
                     /locus_tag="ACG930_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518201.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            1753..2964
                     /locus_tag="ACG930_001028"
     CDS             1753..2964
                     /locus_tag="ACG930_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518202.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            3168..3950
                     /locus_tag="ACG930_001029"
     CDS             3168..3950
                     /locus_tag="ACG930_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFQ0518203.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            4020..4682
                     /gene="trmB"
                     /locus_tag="ACG930_001030"
     CDS             4020..4682
                     /gene="trmB"
                     /locus_tag="ACG930_001030"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFQ0518204.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(4780..6534)
                     /gene="ade"
                     /locus_tag="ACG930_001031"
     CDS             complement(4780..6534)
                     /gene="ade"
                     /locus_tag="ACG930_001031"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFQ0518205.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            6666..7595
                     /gene="comGA"
                     /locus_tag="ACG930_001032"
     CDS             6666..7595
                     /gene="comGA"
                     /locus_tag="ACG930_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFQ0518206.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            7552..8601
                     /gene="comGB"
                     /locus_tag="ACG930_001033"
     CDS             7552..8601
                     /gene="comGB"
                     /locus_tag="ACG930_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFQ0518207.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            8598..8876
                     /gene="comGC"
                     /locus_tag="ACG930_001034"
     CDS             8598..8876
                     /gene="comGC"
                     /locus_tag="ACG930_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFQ0518208.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            8851..9321
                     /gene="comGD"
                     /locus_tag="ACG930_001035"
     CDS             8851..9321
                     /gene="comGD"
                     /locus_tag="ACG930_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFQ0518209.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            9293..9640
                     /locus_tag="ACG930_001036"
     CDS             9293..9640
                     /locus_tag="ACG930_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518210.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            9603..10028
                     /gene="comGF"
                     /locus_tag="ACG930_001037"
     CDS             9603..10028
                     /gene="comGF"
                     /locus_tag="ACG930_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFQ0518211.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            10000..10359
                     /gene="comGG"
                     /locus_tag="ACG930_001038"
     CDS             10000..10359
                     /gene="comGG"
                     /locus_tag="ACG930_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFQ0518212.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            10531..11538
                     /locus_tag="ACG930_001039"
     CDS             10531..11538
                     /locus_tag="ACG930_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0518213.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            11563..12747
                     /locus_tag="ACG930_001040"
     CDS             11563..12747
                     /locus_tag="ACG930_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFQ0518214.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(13184..14767)
                     /gene="abc-f"
                     /locus_tag="ACG930_001041"
     CDS             complement(13184..14767)
                     /gene="abc-f"
                     /locus_tag="ACG930_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFQ0518215.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(14872..15000)
                     /locus_tag="ACG930_001042"
     CDS             complement(14872..15000)
                     /locus_tag="ACG930_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518216.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(15345..15488)
                     /locus_tag="ACG930_001043"
     CDS             complement(15345..15488)
                     /locus_tag="ACG930_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFQ0518217.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(15711..16190)
                     /locus_tag="ACG930_001044"
     CDS             complement(15711..16190)
                     /locus_tag="ACG930_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0518218.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(16263..16547)
                     /locus_tag="ACG930_001045"
     CDS             complement(16263..16547)
                     /locus_tag="ACG930_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518219.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(16625..16819)
                     /gene="ssrS"
                     /locus_tag="ACG930_001046"
     ncRNA           complement(16625..16819)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG930_001046"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(16891..18177)
                     /locus_tag="ACG930_001047"
     CDS             complement(16891..18177)
                     /locus_tag="ACG930_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFQ0518220.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            18315..18986
                     /locus_tag="ACG930_001048"
     CDS             18315..18986
                     /locus_tag="ACG930_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFQ0518221.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            18952..19440
                     /locus_tag="ACG930_001049"
     CDS             18952..19440
                     /locus_tag="ACG930_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFQ0518222.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            19453..20400
                     /gene="prmA"
                     /locus_tag="ACG930_001050"
     CDS             19453..20400
                     /gene="prmA"
                     /locus_tag="ACG930_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFQ0518223.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            20401..21165
                     /locus_tag="ACG930_001051"
     CDS             20401..21165
                     /locus_tag="ACG930_001051"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFQ0518224.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            21398..23611
                     /locus_tag="ACG930_001052"
     CDS             21398..23611
                     /locus_tag="ACG930_001052"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFQ0518225.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            23622..24068
                     /gene="dtd"
                     /locus_tag="ACG930_001053"
     CDS             23622..24068
                     /gene="dtd"
                     /locus_tag="ACG930_001053"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFQ0518226.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            24239..25498
                     /locus_tag="ACG930_001054"
     CDS             24239..25498
                     /locus_tag="ACG930_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFQ0518227.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(25587..26534)
                     /locus_tag="ACG930_001055"
     CDS             complement(25587..26534)
                     /locus_tag="ACG930_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0518228.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            26928..28220
                     /gene="hisS"
                     /locus_tag="ACG930_001056"
     CDS             26928..28220
                     /gene="hisS"
                     /locus_tag="ACG930_001056"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFQ0518229.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            28235..30004
                     /gene="aspS"
                     /locus_tag="ACG930_001057"
     CDS             28235..30004
                     /gene="aspS"
                     /locus_tag="ACG930_001057"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFQ0518230.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            30113..30988
                     /locus_tag="ACG930_001058"
     CDS             30113..30988
                     /locus_tag="ACG930_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0518231.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            31254..33137
                     /locus_tag="ACG930_001059"
     CDS             31254..33137
                     /locus_tag="ACG930_001059"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0518232.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(33212..33496)
                     /locus_tag="ACG930_001060"
     CDS             complement(33212..33496)
                     /locus_tag="ACG930_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFQ0518233.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(33486..34220)
                     /locus_tag="ACG930_001061"
     CDS             complement(33486..34220)
                     /locus_tag="ACG930_001061"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFQ0518234.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            34349..34972
                     /locus_tag="ACG930_001062"
     CDS             34349..34972
                     /locus_tag="ACG930_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFQ0518235.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            35164..36285
                     /locus_tag="ACG930_001063"
     CDS             35164..36285
                     /locus_tag="ACG930_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFQ0518236.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            36292..39420
                     /locus_tag="ACG930_001064"
     CDS             36292..39420
                     /locus_tag="ACG930_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0518237.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            39439..42633
                     /locus_tag="ACG930_001065"
     CDS             39439..42633
                     /locus_tag="ACG930_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFQ0518238.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(42779..43486)
                     /locus_tag="ACG930_001066"
     CDS             complement(42779..43486)
                     /locus_tag="ACG930_001066"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0518239.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14115 a         7770 c         9237 g        12632 t
ORIGIN      
        1 taaaaacgtt gtcgtggtag tttcaaacaa aattcaaaat ttcatcacat tcctaggaaa
       61 tacgcaaact tttctcactt atatagttaa atctgttgag aaaataatca ttattatatt
      121 tgttcaggat actctggcag atcagctttt agtttttcta cttgttcatt gatttgtgtg
      181 atacgtggtt cggcttggaa tttaaaatct tcgatatctt ttttgattgc ttcttggaaa
      241 gcaggaatca cagattcagc tgtttctttt gtttcgatca atgcgctttt aaaatgattc
      301 aggctgttat ttaaatcatt tgtcagagtt gttgcttctt ccaattcttc gatcagtttc
      361 tttcttgttt cattcccgct cctgggcgcc aataacagac ctccgacagt gccagcagca
      421 gctccaaata acagtccttt gaaaaagttt ttaatcatcg caggacacct gctttacgat
      481 tgtttcttga atagctttta gttcttccga tccataacta tcttgatgat tgacaaagtg
      541 aatagaaaaa tcatcctctt tgctgtagcg agggactaaa tggatatgtg aatgaaaaac
      601 agattgatag gctagttcac ggttgttatt caagatatta agacctttca tttctggaaa
      661 agctttttcc aatgcttgag caatcttagg cacacgcgaa aaaacctctc ctgcaagttc
      721 gggatcatat tcaaaaatat ctgctacatg acgtttaggc acaactaatg tgtgtccttt
      781 cgttgcttga gagatgtcta aaaaagcata gaccttgtcg tcttcatata ttttatagct
      841 tgggatttct tgattgatga ttttgcaaaa aatacagttt tccatataaa acatcctttc
      901 tataaagaat aaatacttca gcttaacttt accataagtt aaagctattg taaggaaaaa
      961 aacaaaatac cgtcattttc ttcgtggtat aataaataaa aataaatggc ggaggaaaaa
     1021 gaatgagttt aattatcgat catgtcacag gggggtacgg acatctccct gtgttaaaag
     1081 atatcagttt cgatgtacag cctggagaga tagtagggtt gattggactg aacggagcag
     1141 ggaaaagtac gaccatcaag cacattatcg gtctgctgga agcttcaaaa ggaacgatag
     1201 aaatcaatca tctatcctta aagaaaaata cggaagaata tcgcaaacaa attgggtata
     1261 ttccagagac tccttcttta tatgaagaat tgacattgag agaacatatc gaagtcactg
     1321 cgatggccta cgatatacct atggatatag caatgaaaag agcagaaaag ttgttggaga
     1381 cttttcggtt atctaatcgt cttgactggt tcccagctaa tttttcaaag ggaatgaaac
     1441 agaaagtgat gatcttatgc gcctttttga tcgagccttc tttatatatc atcgacgaac
     1501 catttttagg cttggatcca ctagctatca atgcattgct tgaattgatg gtagaaatga
     1561 aaaaagaagg agccggtatt ttgatgtcta cgcatatttt agctactgca gaaaaatatt
     1621 gtgatcgttt tgtggtctta cataacggag agatacgagc agacggttct cttgagatgt
     1681 tgagaaaaga atttcagctg ccggattctt ctttggacga aatctatatt gctttaacaa
     1741 aggagcaggc acatgagtag tttttttcaa aaacgtttag caagacatca aaagaaaatg
     1801 atgaaatata tgcgttatgt attgaacgat cattttgttt tagtttgtct tttcttgatt
     1861 ggcggtgtgg gattatatta ttctaattgg ttgaaaaccc tgcagccacc gtttgcaatt
     1921 ggagggctca taatctctgt attttggatg ctctgtttat tcgtgggtaa gatggctact
     1981 tttgcagagg cagcagatat tgttttttta cttcctaaag aaaaagaaat gcaaacctat
     2041 ttggaacgag cttttcgcta ttcttgcatt tttccgttga tctttttgat attggcatgc
     2101 ggattggcca tgccattagt ggtggttagt acggagcaat ccttttcgat gtttttcgtc
     2161 tatctgatca tattatggag tttgaaattc agtcatctgc aaatcaagag agcagaattg
     2221 tttcgactag atcaacaagt tattcgttat tggaaattag gctggttttt ttcttctctg
     2281 atctttttgt ttctatcatt ttattggcta atatgggcag gaatagcagg tgcattagta
     2341 caggcaagtc tatattactg gtttttgtgg aagcaacaag aaaaaggatt ggattgggag
     2401 aaaatggtgc atgtagaaga acataggttg catcagatct atcaatttat caatttattc
     2461 acagatgttc ctgaaattac ggcaaagatc aaaagaagac gctatttgga tcctatattg
     2521 actcatatta aaagagaatc aaaaaacact tatctttact tgtttgcaag aagattggca
     2581 agaggttctg attttagtgg tctttatttc cgattagtaa ttataggtgg gttattgatt
     2641 gccggagtag tcgactttta ttttagtctg attatcggtt tcttattttt atatttgatc
     2701 ggtttccaac tgttaccttt agcgaaccag ttccgctata tggttctcgt tcagctttat
     2761 ccaatccata agaatcagaa gaagcaggcg attcagtatc tactcacatg ggtattaatt
     2821 atcgcgtcgg ttatttttgg tttgattgct gcagtcgtat tagatgggca gcagcgatgg
     2881 gttccgctag cggcttattt gattgttact atgctctttg ttaaactata tgtaccaact
     2941 cgtttgaaga agatgtcaga ctgaaaacaa agctgtgtag ggtaaaaatg agaatgaaaa
     3001 atagagcgtt gacagtaaga atgctgttcg ttctattttt tttgagaaaa gctggttttt
     3061 tgaatggcaa ttaaatgaaa aagaacgtat atgtgcttga cgtgtagtgt tcaggcgact
     3121 agaataataa gtactgcaaa acaaagagta agaggacggg agaatgcatg atggagtttc
     3181 agttagacca agagtggcgg ttacgtccca tcaaaggcga cacaggaaaa acatacatag
     3241 gcatgcgtga tgaggacaaa gtctttatta aacgaaacac gactccgatg ttggctgctc
     3301 tttcaaggga aggaattaca ccaaaacttg tttggacaaa acgaacgggg aatggcgata
     3361 ctttgacagc acaagagtgg ctggaaggtc gcttgctgac tcctaatgag attggtcaaa
     3421 gaaacgacgt gattgatgtt ttgtaccatt tacatcattc aaattctctt aaaaccatgc
     3481 tgacccgtat cggtggtcgt gtcatgacgc cggagaagat gctgcaaaaa tatgaaaaag
     3541 aattaccgga agaactccag aaaaatcaat ttctgcaaat tgtccatcgt tttcttcgtg
     3601 agcagatccc gtcaatagat aaggaaaact tatcagtagt acacggagat gtaaaccatc
     3661 gtaattggtt agtatgtaaa aattatttat atctagtcga ttgggattca atcatgtttg
     3721 cagaccctgc ggtggatatt gcaacgattt taggaaatta tgtgccactg tctagctgga
     3781 atcagtggct gatcagttat ggcatacgcc cgactgacga aatgcttgaa aaatttcatt
     3841 ggtatgcggc catgaatttg ctccaagaaa tcaccagata ttgcaaacgt gaagatcatc
     3901 gacggatgaa cgaagaaatt ttacaattaa aacgaatttt cagtggctga ggtttggccc
     3961 aaactctgcg gagatttggc cagacctttt taattagagg aaaggaatgg agataaataa
     4021 tgcgtgtccg aaatcgtccg ggagcagcgg aaatgttagc ggctcacccg aattttgtaa
     4081 ttagtgatcc aacattgtgg aagggaaaat ggaatgaatt gtttgaaaac gatcatccaa
     4141 tccacattga gattggtatg gggaaaggcc agttcatcac tggaatggca aaagcccatc
     4201 ctgaaatcaa ttatattgga gtagaaatgc aggtcagtgt tgtttcgatt gcactagaca
     4261 agttgatcga acaaccgctt cctaacctga aacttctaca tgtggatgga tcagcgttga
     4321 cagagtattt cgctgacagc gaagtagatc aaatctatct gaatttttcc gatccatggc
     4381 caaaaaaacg tcatgaaaaa cggcgattga catataagac ttttcttgct gtagatgaac
     4441 agattcttcg tccaaatgga gaaatccatt tcaaaacaga taatcaagga ttgtttgagt
     4501 attctctggc aagtttttct caatatggca tgatcctcaa acaggtatgg ttagatttac
     4561 atcaaagtca atttgaaggc aatattatga cggagtatga agaaaaattt tcttcaaaag
     4621 gtcaacgtat ttatcgagta gaagctcaat ttcaagataa gaccaaaaag aaaagtctgt
     4681 gaaactaact ttctgctttc ataaaaacat taatatccat aaataaatcc cagaaaatga
     4741 acattacaga tgtaatgtat tttctgggat ttatttgatt taaaatgtat ttatttcatc
     4801 ggtttttcca caaggtggaa tcaattggaa gcgagaaaat gaaaataatc ctttgtcggt
     4861 gatcttcaat tcgggtatga cagataatgt taagaaagaa agtgtcaaaa aaggatcaaa
     4921 ggttttagct gctcctagtt gatgtgcttt agttattaat tcattcaact gttcatagac
     4981 gatcgaaaaa ggttcctgtg tcatgattcc gcctatagga agagaaacac aagctatttc
     5041 ctgctgattg ttgacaacgg tcatcccgcc acctttttga atcaaaagat tagcagcata
     5101 cagcatatcc tcgtcgtttg tcccaacgac aactagatta tgcgagtcat gggcaatcgt
     5161 tgtcgctatc gctccttgtt tcagctgaaa tcctttcact atgcctaatc caatgtttcc
     5221 cgtttgatgg tgacgctcga tcaccgcaat ctttaattgg tctttttcga ttgaaggaat
     5281 gaatcgttcg ccttgtcggt ccactttttc taccaaatct ttagtcacta gactattcgg
     5341 gataatttcg atcacatggg cttgtgaaga agaaagaagc agctctaacg aatgtggatt
     5401 taatggttga gcgtttagtt ttggcagaca acacgtatat gaatttgaat gatcagcaaa
     5461 taaatggtct tggagttgcc cagattgaac aactaatgtt cccttataga aaacttcatg
     5521 aattggcagc ttggtaagat cgtctgttaa gaagaaatca gcttgatacc caggggcaat
     5581 cgcacctagt gttttcaaat caaaacattc tgctgcattc aatgttgcca tctgaatggc
     5641 ttgtaatgga tcgattccaa gtgcaatagc ttgacggacg atatgatcga ttgatccttc
     5701 ttttactaaa tcattgatca gtttatcatc ggtgacaaag aagcatcttc ttgaattttc
     5761 aggtgtgatc gccggtagta gcgatgccag atcttttgca acggtccctt ctcgaaccat
     5821 taaatacata ccaagatcca aacgttcttt agcttctttt gcagttgtag cttcatgatc
     5881 cgtccgaata cctgctgcag gataaacatt taactcttcc atgccgatac cagctgcatg
     5941 cccgtcaatt tttttcttat gctggtgcat caattggatc ttttctagga tgtctgtttc
     6001 attatttgct actgcttgat agttcatgac ttcagctaag cctaaaactt cgggtttttg
     6061 taaaaaaggg gctaattttt ttgcatttaa atttgcacca ttggtctcaa aaggggttac
     6121 aggtacacaa gaaggtagca taaaaaagat attcatgagt gtttgtcttg catcttctat
     6181 cataaactca agacctgtac tcccagcaat gtttcctatt tcatggggat ctgtcactac
     6241 agtagtaact ccatgaagca aggatacttt tgaaaattcg cttggtgata aaagtgagct
     6301 ttcgatatgc acatggccat cgatgaatcc tggcactaga tattgcccat tagcattatg
     6361 tacgcttttt ccttcgtatt caccgattcc tacgatcatt ccttcgcaga ttgctacatc
     6421 tttttccatg atttctttcg taaagacgtt gacgatctta gcatgcttga tcactaggtc
     6481 agcaggcttt tttttacttg ctacttcgat atatttcctt aatgttgttt ccaatggagt
     6541 gcctcccaag ataaattttt ataagtataa cataaattcg gtttttgcca atattttttt
     6601 gtaaattcat tttatttgaa acaaaaagat caaaaagacg tatgtttttt gtggagggga
     6661 gaataatgga aataaaacga ttatcggatc aaatgataag tgaaagtttt gccaaacatg
     6721 cccaagacgt atatatattg ccagcttcag aagtatttta catctatttt cgctatggaa
     6781 aaaaacgaac attctggaag aaagtctctt cggcagatgg acagcaactg atctcaagat
     6841 ttaagtattt gggacagatg gatatcggag aaaaaagaaa agctcagtta ggtgcattta
     6901 cttattcttt agaaaaacag gaagttcgtc tgcggttgtc ttctgtagga gattaccttc
     6961 aacgagagag tttagtgatt cggctattat acggtacttt tgaaacaccc catcgttgct
     7021 ttagttctcg agattttgca actattttac agaaaaccgt cagacgtgga ttataccttt
     7081 tcagcggacc agtcggatca ggcaagactt ctctaatgta tcggttggct ttggaagaaa
     7141 aattgcaagt gattactatc gaagatcctg tagagataga agaaccgttt tttctgcagc
     7201 tacagatcaa tccgaaaata gcacagactt atgatacact tttgagactc gcattacggc
     7261 atcgtccaga cttgctaatc attggcgaga taagagatga atcaactgca catgctgcgg
     7321 taagagcagc actaacaggg caccgggttt ttgcaaccgt acatgcacgc aatcttgaag
     7381 gtacattggt cagaatccat gaactgacaa agaaaaaaga agagctatct gaatgtttag
     7441 ctggtgtcat ttatcaagaa cttttggaag atgccaatca ccatccttct gttttatgga
     7501 gttatcaatt tatggaggaa gaatcagtaa aaaaatcatg ggaggaaagt tatgaagaag
     7561 ctcaggaaaa tatttggcag tcagaactat tctaaaggat taacaagaag ccagcaaaac
     7621 cagtttgcac aaaccatggg agaactgctt ttatctggtt ttagtctgca agaatccctt
     7681 tatttattac tcacgatccg ttcgtttcca cctgttattt tggcaaatat ccaacatcag
     7741 ctaaaggaag ggcaagcgtt tagtgaggta ctttcgcaaa taggatatgg agcagagcaa
     7801 ctggtacaga tcgagttagc tgaacgtcat gggaatctgc cgacaacttt gttggaaatt
     7861 gccaaacagt ttcggcttgt tgaaggattt cgcaatgatt tgaaaaagct gcttgcatat
     7921 ccgatgctat tgctcacctt tttgctaggt atcttgttta gtatgcggtt gttcgttttg
     7981 cctcagctta ttggttcagg aatggtcatg caagagcatt ggggtattca gctgatacaa
     8041 gtctttcatt ggtatgttct actattcatc ctagcggtta ctctattggc tttactagta
     8101 aggtatcgtc tgatgaagtt gtctcctgtt gatcagagtg aatggataag cagacaatta
     8161 ttgattggac cgatatattc cttgtatcaa tcggcttatt tgtcactaga gattggaaag
     8221 ctttttcatg aaggtttcga attaaggcaa atcatagtct gcttaaagga aacgaaacaa
     8281 gaaagtctga ttcagcatct tgcctctaag ttgattcaag gattggaggc aggtatgtca
     8341 ttggctgagc agttccagaa ttatcgtttt ctatcagaag aattcagtaa aattgtttta
     8401 cagggagagg caaagggaag tttaggtaaa gaactgattt tttacagcga atggacaaga
     8461 aaacagcttt tcaaacgtct tcatcactgg atgcatttta ttcagccaat catttttttg
     8521 ggcgtagcgg ctttgatttt attagtttat gccgctgttt tattacctgt ttacggaagc
     8581 atagaggagg ttttgccatg aaaaagagaa aaatatctta ttatagcggt tttacattga
     8641 tcgaaatgct aatcgtctta ctgatcatca gtgtattagt gttgttgttc gtccctaatt
     8701 tgtcgcgtta taggaatcat gtagaccaag aaagtcgtga agcgatcatc cagttggtag
     8761 acacacaaaa agagctctat gcgcttcaaa ataatggaag agttcctact gtggaggaat
     8821 tgttgaatga aggctatatc aaacgagaac atgcagaaat ctatcagcgg ccttgaaggt
     8881 aaggttttag catcaggata tacgttgttt gaatcactct tactgatttt attacttaca
     8941 acgatccttt cttttccagt tctcgcattt tctgcatgga agaatgaatt ggcagtctat
     9001 caatttttcg gccaatttga aaaacgaatc tattctacgc aaaaaatcgc tattgtgaat
     9061 cagatccaaa caggctttta ttggaatagt gaagagaatc aaatcatttt tcatgttccg
     9121 aatccagata aaataaattg ggaagtatta gatattcctg atgagattac cttgaaacgc
     9181 catgcttcta ttacttttgc tgctagaacc gggaatgaaa gttcactaaa agcttatcaa
     9241 ttttattggg aagaaaaaga gcggacgatt acgtatcaat tccagatagg gagtggtcgc
     9301 tatacaaaaa gaattgaata aaacaggatt tgttttgttg gagtccctta cagcgcttat
     9361 gatcgcttct gtctgtgtct acttagtgag ctttggccag ctgtttttgc ttcaggcaga
     9421 aaagaaaagt ggggaggaac tgctatttat tcgaatgatt tatgaagata tcaagacgca
     9481 gcggatgtat cacaaaagac cagagcgaag ggaagaaatg atcccatacg atatccaaat
     9541 tgtcgataat aatggagtaa tcgaaaaagt gtttgtcaat atggagaaag aagcgatcag
     9601 tattgaaaaa acaagtaatt ccagcattta cgctgattga atgtctaatt ggactgatga
     9661 tattgagcag tctattgctc acattcaatc ttttgattca gcaaaccatc caagtaagtg
     9721 aatttttgca gcgtaaagat caaaaagagt ggctaatatt tttagcacaa ttagaagaag
     9781 aactcaagag cagtcacaat gtctctgtga aaaatcagca actgcactac acgatcgagg
     9841 ataaacagta tatcatcgaa agatatcagg caatgatacg taaaagaaga acttccggcg
     9901 gacatcaacc tatgttaaca agtatcactg agcttcaatt attggaaaaa gaacacacaa
     9961 tttcttttta tgtacacttt gaaaatggag aagatggata tgccatatgg acaaaaaacg
    10021 atcagtagaa aatgttataa gggctctatt ttattttctg tcttgctttt atttctttta
    10081 tgtacgtttt tattgatggc agcattagaa agctaccgtt tgtcaatgga tcttaatata
    10141 cgaatcaaaa attattatat agcaaaaata atgaagcaga tggctttatc ggaacagtct
    10201 acgcttgccg aaagttcgga aggagttttt tactacacaa ctggatctgt aacatatcag
    10261 tgggtacaac agtccctatt cttagaggtg gaagtctcac cgtttatctt tcggttcaca
    10321 gaagaagtaa aaaatgatac agatactagt acagaatgat ggaatgttcg tgaaaacgcc
    10381 ctcttttctg ttataacact gtttttaata aaaaaatgtt tgccgtttca caaataaaaa
    10441 acagtgaaaa cgattgaaat tttgtcaatt gttcgataga attaaacagg tgaaaaaatt
    10501 gttataatat atctagaaat gaggtgcacc atgttaccag aaaaaatgga acaagggttt
    10561 aatcaaaacc tggaagctat tcagctttta cagaatgcat tgggaacttc ctttttagaa
    10621 gcctatgtcg aaaatgcaga aaatttaata gatgattatc aagtacgtgt ggtggatgga
    10681 gtgccgacaa aagagacaac gcaacggatc acagctcttt atgaagagtt gaagaaactt
    10741 tctttcgagc cagaagaatg gcgcagactg tctcaattac ttttattgaa gggcagccag
    10801 acagaacatt tgcaggcgaa ccatcaactc actcctgata gtatcggttt tttatttgtt
    10861 tttcttattg aacaactata cacaaataaa aaagcaccgg ttaagattct ggatattgcg
    10921 gcaggaatgg gcaacttgtt attaacagtt cttttaaacc tatcgaatgc ggggtaccaa
    10981 acagaaggaa ttggtgtgga tattgatgat acattgttgg ctgtcgcagc ttctacaagt
    11041 gatttgacac aagcaaatgt tcaatacttt catcaagacg ggttgcagga attattaata
    11101 gatcctgtcg attttgcaat cagcgatttg ccaatcggtt attatccgaa tgacgaaaaa
    11161 gcaaaagagt ttttaacaag taccgaagaa ggccatagtt atgcacatca tttattgcta
    11221 gagcaatcaa tgaaatatgt gaagccggat ggttttggtt tgtttttgat gccgagtgga
    11281 tttttagaaa cggatcaaag tgaagaaatc aaaaaatggt ttaaagaaga aggttatctt
    11341 caaggaatga ttcaattgcc agatgaattg ttccgtaata aacaatcgca aaaaagtatt
    11401 ttgatcttac agaaaaaagg accacaagca caacaagtaa aagaagtctt gcttgtgaaa
    11461 cttgcttcat taaaagaacc agagaaggtg acggaatttt tcaacgagtt taaaaactgg
    11521 aaatcatctg ctctgtaatc attcaacgag aaggagagtc atatgtctaa aacaattgca
    11581 atcaatgctg ggagttcaag tttgaaatgg caattatatc aaatgccaga agaaaccgta
    11641 gttgcgaaag ggatcgtcga acgtatcggt ttacaagatt ctatttttac catcaagtac
    11701 ggcgataatc aaaaattcga acaaatcatg gatatcgaaa accacgaagt agcagtaaaa
    11761 atgctgttag atcagttgat tgaactgcaa attttaagct cttatgatga aatcaccgga
    11821 gtagggcacc gtgttgttca cggaggagaa acttatgggg attcagtagt gatcgatgag
    11881 aaagtaatgg accgcattgc tgaattagca gaatttgctc ctttgcataa tcctgcaaac
    11941 ttaatgggga tcaaagcgtt taaaaagatt ttacctgaca ttttgagtgt ggctgtattc
    12001 gatacatctt tccactcaac aatgccaaag caaaattatt tatatagctt accggtgtct
    12061 tattatgaag atttcaaagt aagaaaatat ggcttccatg gcacaagtca tcgttatgtg
    12121 tcggaacgtg cggcaaaatt attgaacaaa ccgatcgaag aactaaaaat catcacttgc
    12181 cacttaggaa atggtgtatc gatcacagca gtcgatggag gtaaatccat ggatacttct
    12241 atgggattca caccattagc tggggtgaca atgggtacac gttcaggtga tatcgatcca
    12301 gctgttctcc catatttaat ggaaaaatta gagattgata ttgatgaaat gatcaatgtt
    12361 ttgaacaaga aatctggtct gctaggccta acaggattgt ctagtgatat gcgtgatctt
    12421 gaaaagaact atgaaaaaga acatattcgt ttagcttatg acattttcgt ggaccgcatc
    12481 cgaaaataca tcggcggtta tgtgacaacg atgaatggtg ttgatgcaat tgtctttact
    12541 gctggtatcg gcgagaatga cggacatgta cgtagtgaaa tcatcaaagg tatgtcttgg
    12601 tttggttgtg aaatcgatcc agcgttgaat gaattgcgtg gtgaagaagt agatatctct
    12661 acaaaagaat caaaagtaag agtattagtg atcccaacag atgaggaact aatgattgcc
    12721 cgtgatgtgg agcgtctgcg cggctaagcc aaagcattcg ttaggataaa agatgaaacg
    12781 catgcaagag ggaattcttg catgtgtttt ttttgcggag aagaccgcaa aatggtaatt
    12841 taacttcaat ttcccttctt ttttacagga tcttcttagg gaattttgct tggaaaagtg
    12901 gtcaaaaggg aaaagactgg cattttattt attgattttc aggaaaatcc caatatttta
    12961 ttttcattca tctttataag ggacattaca tatgtaaaaa gaaaaaacat ttttagatca
    13021 gcctcgtggg ctgtcgactt tattcttcgc tttatgttta gctagaaaac cgatccgaaa
    13081 cattcattga tcgaataata aaaacttgat tttccacctg tactttgcct gaatcgtgaa
    13141 agcacaggta tgaaaatcaa gttttttgtt gcgaaaaaac gtcctagtca atcagttggc
    13201 cgagcggctg gcggctgatc tgctcctgat caataacgag tgcttcttgg aagtgttgct
    13261 gcaaaaagta gcggtcatgg ctgactgcta ggagcgttcc ttgatagtct tgcagcattt
    13321 cttcaatttc ttctcgagca tagctgtcga ggtgattggt tggttcatcc aaaatcagga
    13381 cgttgatttt ttctaaaaag agtttcagca acgccaaacg gattttttca ccaccggata
    13441 aatctttgat ccgtttaccc acatcgcttt gataaaagcc acttttggct aattgccgtc
    13501 gagcgacttc ttcgtttcca gtcaatgtga tggcgtaagc cagcaaacgg ctatcgggat
    13561 cggcaaactg cagctgctgc ggcaaataac cgatttgcaa gctactacct aatttgatgg
    13621 tgccaccgta aggcttttcc tcaccgagta ataatttgag taaggttgat tttcctgcac
    13681 cattgtcgcc gatgatggct aaatgatctc cacgatagac tgcaaaactg ctgtctttga
    13741 atagtacttg atcagcgtac tgctggtgca agttttgaat gatgaaaact tctttgccag
    13801 attttccacc attagacaag ctttgcagcc gatttttcgg gggaggtggc ggtttgacga
    13861 gtgtcagttt cgccaggcgg cgttccagtt ctttggcttt tttgaagaag gactcattgt
    13921 ctccttcatg tgcccactga cgaaaacgac gaatcatgac tttcaaccgc tggacttctt
    13981 tttgctgcag ttcgtaattt tttgtcagct cagccaagcg agcttctttc aagactcgaa
    14041 aacggctgta gtttccggga tactcaatca atgcaccttc ttccagttcc catgtttttg
    14101 tggtgacttg atcgagaaat tgccgatcat gagaaacgac cagaaccgat ttttttgtat
    14161 tctgtaaata gttttccaac cagcgaatac tgttaagatc taaatgattg gtcggttcat
    14221 cgagtaaaag taaatcggca tcggctgcta aaattttggc taaagcgact ttaactcgtt
    14281 cgcctccgct aagttctgtt aaccgtgctt cctgacggtg tggaatccct aagccttgca
    14341 agatcgctgc aatccggtct tctaatacgt aaccgcctag ttcttcaaag cgatgctgca
    14401 gctcaccgta acgggccaga cacttctcta agtttgtatc tggttctgtc atcaatgctt
    14461 cgtagcgact catttgctgt ttgaggtcct gtatctcagc ggcagaatgg agcaagtagt
    14521 ggttgacggt cgcttcggaa actgtaagtt cttgttcgac cgtcccgatc tttaagcctt
    14581 ttttgcgact gataacaccg ctgtcgacac cttctctgcc ggtcaagatt tgtaaaaagg
    14641 ttgatttgcc agttccgttg ataccgacta aggcaatttt ttcaccagct tcaatttgac
    14701 aggataaatc ctcaaataat ggattcccgc cgattgtttt tttaatagaa attgcttgta
    14761 tgatcatgat ctctctcctt gagaccactc aaaaaggcca tggttatcca tggcctgtgt
    14821 tatttaaact cagattatca tgagaaaaat accttgagat ggccattgat tttacgtgaa
    14881 ttcaactgtt ttggacaaac ttgtcccgtc aacagcaact gtaaaaccaa ttgcatggct
    14941 aaatgcgata tggtatcgtt ggtaattttc attacttgtt attttagtca tgcgcatcat
    15001 agtattttcc ctccttcgtg tagttgtctt ttccagtgta cctgaaagtg tcagaaagtt
    15061 caactagcgc tgacatttac ttaatattta tcgatgtgta attctgtcag agagcttttt
    15121 ttatctgact gagggtaatg tctcgtggac cacatcattg tattctgagc taaaccagcg
    15181 ttcaggcgaa atcatatggt gtttgataaa aaactttgtc tacatgactt ccttttgcca
    15241 tttgcttaat accgttgcat taaacagctc ttctctttgg aaatctcacc aacatcgcgt
    15301 tcaggagtat cgttgtggtt gcaatggcaa gcggtagcct ttcatcaatt cttgaatgat
    15361 ttaccgaatg tagcacttgc cttctcgcgg tacccgaacc cgaaataaaa ttttagtttg
    15421 gcgataaaat cggtatccgc catcgatact tcatattttt tcgtatcaga ttcatcggaa
    15481 acttccacat tgacgaacca ataagctttg gcatgcttag gtcgttttaa accacaccag
    15541 ggcgactaat cgccctggtg ttcacttttt tttattttac ttgaactcat tgactgtttt
    15601 ccctttattt taaacattat aaagaccgat gagtgcttgc cgcgtctttt gtttttatca
    15661 cggttttttg tgcaaaaaaa cctgccgata gttggcaggt cgtctacgtg ttaagctttg
    15721 gtgtggtctt tagctggcaa ttggttttct aaatcagttc ggacaacaag cacatcgcaa
    15781 gctgcgtttc taataacata ttcagaaaca gaaccaataa ataaacgttc tacagcattc
    15841 aatcctgtgg ctcctaacat aatcaaatct acttgattat cttctgggat ttctctggca
    15901 ataatttgtt ttggtgagcc atattctacg acagaggtta cattattcaa gccagctttc
    15961 ttcgcattgc tttcataatc tgccaatgtt tgctttgcca tttcagtagc ttgttctgca
    16021 agcattccat caaaggatga aacggtttgg aaagaacgtg tgtcaatgac atgtgctaat
    16081 agaagttctc cgttatttcg gatagctaca ttgaccgcct ttttaaaagc taattcagct
    16141 tcatcagaac catctacggc aaccatgatt tttttgtatt gttgtaacat aagcattcac
    16201 tcctcaagtc aatcgtattg tactctttta ttgtagaaca ctttagggaa aaagagaatt
    16261 atttactgct ttggttcagc aatttttttt gcaaatcgga tactgaaggt ggcagaaaca
    16321 ataattacga tcagtaaaaa gaccaaggca ataaagcgtt gattgaaaaa agctgttaaa
    16381 atacccatta cgcctaaaac agcatatgca gctccgtaaa attgtaggaa tccttgattt
    16441 ttatcatttt tgttgatcaa tacaaaaaag atatcctgtt tattaaataa ataatagcta
    16501 acgaataata atactaaagt ggcgataatc attaaaatcc taatcatgaa caaatcctcc
    16561 aaaataagca acaaatagaa aaagcaattt gccaagagca aattgcttta ttctttaaaa
    16621 gatggtaatc tccgttaatg ccgttgtttg tcctgtagta ttgatcccgc gaattcaagc
    16681 aggtgggtcc catggtcgta gcttcgaact accaaatgat aaggcatgtt accagcagtg
    16741 acacaagacg ggtcccaaga tatcaataaa aatgttcggt caacacacaa agaggacaat
    16801 tcgaacatca cagatttccc acctctatag tagcatatga atttaaaaag agcaatgaga
    16861 gagctcgcag aaacagaacc gttttcttgt ctagtttttt ggaggatgct ttttccactc
    16921 ttttatacgg taatactgtt gacccagagc ctgttcatat ttccctgtat cttttggctg
    16981 ataatactga gcattcttca gtttatctgg taaatattgc tgattgaccc aagcctgatc
    17041 aaaatgatga ggatactgat aacccacgcc acggttgagt gatttcgcac ctttgtaatg
    17101 gctatctctc aaatgatcag gaacatctcc agctttgccc tctcgaatat cagcaagtgc
    17161 tgcatctaat gccatgtagg cagaattgga ttttggcgac aagcaaagat cgacgacgac
    17221 gtctgctagt gggatacgtg cctcaggcaa tcccaatttt tcagcagcta atacagcgtt
    17281 cactgtacga gccgcagcag caggattacc taaacctata tcttcataac cgataaccat
    17341 cagacgccgg caaatacttg ccagatcacc tgcctcaact aaacgggcga gataatgaag
    17401 tgcagcatcc acatcacttc cacgaatcga tttttgaaaa gccgaaataa cgtcataatg
    17461 agcatctcca tttttgtcat gggtaagagc ttttctttgg acacattctt caatgatcga
    17521 cagtgtaaga tgaatccttc cttctttatc tgaaggagtc gatagtgtag ccagttccag
    17581 cccattcaat gcactccgca aatcgccgtt cgttgcacgc gaaaggtgaa gaagagcatc
    17641 ttcgtctaac tggattgctt gttgtccaag gccgcgttct ttatccctta aagcatgttc
    17701 gactgccaac tggatgtctt gttctgttaa tggtttgact tcaaagatct gtgtacggct
    17761 gcggatcgct ggattgatgg taatataagg attctcagta gtcgctccga tcaagatgat
    17821 tcggccactt tctaaatgag gaagcagaaa atcctgtttt gttttatcta atcggtgtac
    17881 ttcatccaat aagaggatca ctgtaccact catttttgct tcttccgcta caacttgtag
    17941 atcctttttt gaatctgtag cggcgtttag catgcgaaat gcataattag tagagccggc
    18001 gatcgcactt gcgatactcg tttttccagt accaggaggt ccatatagaa tcatggaaga
    18061 gagcatgcga gcatcgacca tgcggcgtat gatttttcct tccccgacta gatgctgctg
    18121 accaacgact tcatcgatcg ttcgaggtct catgcgataa gccaatggct gttgcatagg
    18181 attttcctcc ttcttgtttt tacgtccctt aattatatca tatttagcaa gatgcctaga
    18241 aagaacagcc ttctgttgtt ttgttttcat agcttatcca actaatattg tgtatgataa
    18301 agtaggtgag aaaaatgacg gataaacaaa agatagatga atttttttgg aataaaacga
    18361 cgccagaagt ggcacgggat ttattgggga tgtatttgga gcatgacaca ccagaaggaa
    18421 gattagctgg atatattgta gacgcggaag catacctagg tccagaagac gaggccgccc
    18481 atagctatgg tttaagaaga acaccgcgtg tgcgggcaat gtatgaaaaa ccaggtacga
    18541 tctaccttta cacgatgcat actcatcgga ttttgaacat cattactcag ccagaaggga
    18601 ttcctcaagg agtaatgata cgtgcaatcg aacccgccgc aatgattgat caaatgagta
    18661 aaaatcgtgg cggaaaaact ggtccagata tcagcaacgg tccgggaaaa ttagtggaag
    18721 cattagcaat tcctcaagaa ctttatggtc agtctatagc agatagttcg ttacgcttag
    18781 tttttgagaa aaaaaagaca ccaaaaaaga tcaatgcttt gcctagaatc ggtatcccaa
    18841 acaaaggtgt atggacagaa aagccgttgc gttttgttgt gtcgggaaat ccttatatct
    18901 ctttacaaag aaaaaaccaa atcgagaaag attggggttg gaggaaagaa aatgaaaaag
    18961 aaggatctat taacatattt agatgaaata attgaaaaac aagtgacaga ctatgatgta
    19021 gctttagatt gggatacaaa aaatcatacg atcgagatcg ttgttcgctt gtttgcagaa
    19081 aataaagcac aatttgagat tgatgatgca gaagggatcg tttcgcaaga accaattatc
    19141 gaatttgaag acggcgtact tctttttaat cctcagaaat ctgtttttga tgaacgcaat
    19201 tatctagcag taatccctta tgaaggaaaa aaagggttgg caaaatcagt agctgattct
    19261 ttagtggaat atctaaatga agtattagct caagggcaaa gcgatttgct tgattttttg
    19321 gatgaagacg atgacgaagc tgtattcgag cttcactggg ataatcagca actagcagaa
    19381 ttagtagaag taaaacagca aaatgaagca gatacttatt taccgtaccc aagttattaa
    19441 ggagtgacag atatgaaatg gaatgaagta aaagtagaaa ctgaaagtga agcagtcgaa
    19501 gcagttgcta atattttgat ggaggcaggg gcgagtggtg tcgcgattga agattcttta
    19561 gatgttgaac attttcagtc ggatcaatat ggtgagattt tagataaaaa tgattttaca
    19621 tcgctgaaag aaggcgcact agtcatggct tattttccgg aaacgacttt cttaccggaa
    19681 atcttgcctt ttatcaaaga tcgtatcaca caattacctg agtttggtct agctattgga
    19741 aaaaataaag taacagttag tgaagtagag gaaagcaact gggcaacagc ctggaagaaa
    19801 tactatcatc cggtgcgtat tacgcgaatg ctgacggttg cgccaagctg ggaaaactac
    19861 cagacagaag atcctctaga aaaaattatc acactagatc ctggtatggc atttggcaca
    19921 ggcactcatc ccacgacttc cttgacattg acagcactag aaacagtctt gcgtggtggt
    19981 gaaacattgc tagatgtggg aactgggtcg ggcgtgctaa gtattgcagc aaaatatctt
    20041 ggtgcaaaag atgtctatgc ctttgattta gacgaagtag ccgttcgttc ggcgaaagaa
    20101 aatatggata tgaatgaaat agccaaagat gtccatgtat cagctaacga tcttttgaca
    20161 ggaatcgaga ttgaaagtga tgtaatcgtt gcgaacattt tagcagatat catcttattg
    20221 atgatcccag atgcttggcg tttactgaag caaacaggca cgctgatcgt ttcaggaatc
    20281 attgaagaga agaagcaaat ggttctggat gccatgttag aacaagggtt tatcgtggat
    20341 caaattttcc agcaaaaaga ctggtatgca attattttga aaaaaccaga ggtggaatag
    20401 atgcagcggt attttttaaa agaatcatat gaatcaaaag actattttgt tttagaaggg
    20461 gaaaactatc accacattgt acgggttatg aggatggaac ccgaggatga agtttttttg
    20521 gcattcaatg atcaaatagc cattgttgca gaaatcacgg agattactga agaggctgtt
    20581 tatctgaaag aaattaaaaa agaagaaaat caaaaggaac tgccaagttc gattaccata
    20641 gcgagtggct atcctaaagg ggaaaagctg gattggatcg ttcagaaatc cactgaatta
    20701 ggagcgcaag cttttcttgg tttcccggca tcagcctctg tcgttaaatg ggatgcaaaa
    20761 aaacgtatga aacgacaaca acggcttgaa aagattgctc aagaggcagc ggaacaatcc
    20821 catcggcaga tcgtgccatc agtagagtta ttggaaacga aacaagattt atttgagcgg
    20881 ctagatgatt atgacgtggt cttggttgct tatgaggaat cagcaaagca aggcgaaaaa
    20941 tcaaatgcag ccaaaattct tagtgaaaca aaaccagata gtcgaatctt agctgtcttt
    21001 ggaccagaag gtggattatc ccgcgatgaa gtcgattatt ttgtagaaca caaagggata
    21061 ctttgtggat taggaccaag aatccttcgt acagaaacag cacctcttta tttattaagt
    21121 gctgctagct atcaatggga attaatgaat ccttctttca gctaacgttc ttcattaata
    21181 aaagagtatc gacagaaaga attgaaaaaa tagtcaacaa tttgtataat agaaacaatt
    21241 atttatacaa tggatacgaa aaatcgtttg aaaaagcttt taaaaagcga acatttccgt
    21301 aaaaaaacgt ataactgcac ggattttggg acaattatca aacagatatt tgtcccgatt
    21361 cccgttttac cgaaaaaaga aagggggatc gattcctgtg acaaaagaag aaattttaac
    21421 gggacccggt gtcataaagc tcgttagtca atacatgggt cccgaacatg tagcatttgt
    21481 tgagaaagca tgcgaatacg cgactgctgc acatgacgga cagtttagaa aatcaggcga
    21541 accctacatt attcatccta tccaagtcgc aggtatatta gcagatttaa aaatggatcc
    21601 ccatacagtg gctacaggct tcttacatga tgttgttgaa gatacagaaa tcactttaga
    21661 agatctgaga gaagaatttg gcgatgacgt tgctatgtta gtggacggcg taaccaaatt
    21721 agggaaaata aaatataaat cccacgaaga gcagctagca gaaaaccacc gaaagatgct
    21781 gctagcaatg gctcaagatt tacgagttat catggtcaaa ttagctgata gactacataa
    21841 catgcgtacg ttgaagcacc tgcgagaaga taagcaaaga aggatcgctc aggaaacttt
    21901 agaaatctat gcgcctcttg cacatcgtct agggatcagc cggatcaaat gggaattaga
    21961 agatacagca cttcgttatc taaatccaaa acagtattac cgtatcgtcc acttgatgca
    22021 gacgaagaga gaagaacgtg aaaaatacgt aagtggtact gttgaagata ttcgaatagc
    22081 gacagaagag ctggggattt ttgcagaaat ctatggacgg ccaaaacaca tttattcaat
    22141 ctatcgtaaa atgaaagatc agaaaaagca gttcaacgaa atttatgact tgctagctat
    22201 tcgagtgatc gtagattcaa tcaaggattg ttatgctgta ttaggagcaa tccacacaaa
    22261 atggaaacca atgcccggca gatttaagga ttatattgcc atgccaaaag ctaatatgta
    22321 ccaatctttg catactaccg tgatcggtcc ggcaggaaat ccggtagaaa ttcaaatccg
    22381 aacacaggaa atgcatgaaa tcgctgaatt cggggttgct gcacactggg cctataaaga
    22441 aggaaaaaat gaaaaagtag aaccagatgg tatgacgaaa caattaagct ggttccatga
    22501 gatactcgaa cttcaagacg aaagctatga tgcttctgaa tttatggaag gcgtaaaagg
    22561 agatatcttt agtgataaag tctacgtctt cacaccaaaa ggagacgtta ctgagttacc
    22621 aaaaggatcc ggaccattgg actttgcata cagtatccat acagatatcg gtaacaaaac
    22681 cactggtgca aaagtaaatg gcaaaatggt gcagcttgat tacaaattga aaaacggaga
    22741 tatcattgag atcatgactt ctccaaattc atttggccca agtcgcgact ggttgaaatt
    22801 agttgctact agcaaagcaa gaaataagat caaacgtttc ttcaaagccc aagatcgaga
    22861 agaaaatgtg atcaaaggcc acgaatccgt ggtcaaatgt attacagatc taggatttac
    22921 gcctaaagat attttgacga agaacaaact gcaagaagca ctcgatcgtt ttaattatca
    22981 aacagaagat gatctctatg cagctgtagg gtatggagaa gttagcccct tgacgatggc
    23041 caatcgtctg actgaaaaag aacgtaaaga acaaaaaatc gagcagcaaa agcaagaagc
    23101 agaagaaatc atgaatcagc cgaaaaaaga acctgacaaa atgaaagtac gtcatgaagg
    23161 tggcgttgtc attcaagggg tagaaaactt actaattcgt atcagtcgct gctgtaatcc
    23221 gattcctggt gatgatatcg ttggttatat cactaaaggc agagggatat ccattcatcg
    23281 tcgagattgt ccgaatgttc agcctgacaa accaaatgta gcagaacgtt tgattgaagt
    23341 cgaatgggaa gatacatcga atacacgaaa agagtatgat gcagatttgg aaatttacgg
    23401 ctataatcgt tcaggcttat tgaatgatgt acttcaaaca gtcaatgcgc taacgaaaaa
    23461 tctcaacagc gttgaagcac ggacgaataa agataaaatg gcgacgatcc atttgacggt
    23521 tggtatccag aatttatccc acctaaagag tatcgtggat aaaatcaaag cagtacctga
    23581 tgtctacagt gtacgccgga cgaatggata ggaggacaga tatgagagca gttgttcaac
    23641 gggtaagtaa agctgctgtg tcagtcgatc agcaagaaat tggaaaaatt ggctacggcc
    23701 tacttgtttt attaggcatt catgaaaccg atacgcaaaa agatgtggac tatctggtaa
    23761 aaaaaattgc acaaatgcgt atttttgaag atgaacaagg aaaaatgaat attagtgtag
    23821 aagatgtggg aggacaaatt ttaagtatct ctcaattcac actgtttgcg gatacgaaaa
    23881 aaggaaatcg accaagcttt gtggaagccg cacgaccaga aacagctatt cctttatacg
    23941 aatcattcaa tgaaggaatc agaagtcgcg gcatcacagt cgctaccgga caattcggag
    24001 cagatatgtc ggtttctctc gtcaatgatg gacctgtaac gatcattatt gattctaaaa
    24061 acaaataaag taatctggtt ttcactagta aaaactatga aacacgtcgc ttaagttaga
    24121 ctgataaact ctaacttaag tggctttttt gtctgcaaaa agcgcttctt ttgtcagcag
    24181 tcggaaaaaa agttaagctt aaattataca agttattttt tataggaggt tgctgaagat
    24241 gaaagaagta ccagtagtag atatcaaaat cacagattta aaaaaattgt atcaaaaagg
    24301 atacaacatg ttggaggagt tacgccatga agcggacgct cccgtcgtca aagcaaagat
    24361 tttcaataaa gaagctatca cgatctacgg atcatcagca gcaaaagtat tttatgatcc
    24421 aaggaatttc aaacgaaaag gtgctatgcc aaaattagta ttgaagacac tttttggtca
    24481 aggtggagta cagactttgg atggagctgc tcatcaccat cggaaaaata tttttatgga
    24541 tctaatgaca ccggaaagaa tggaagatta tcatcgtatc ttagataaga atctgacaca
    24601 agcacttgaa gcacagcatg gtcaatttga actatttgat ttaagtaaga tggttttctt
    24661 tacatctatt tgcgagtggg caggtatcaa tttatcagcg atttctaaag atgaggtcga
    24721 aaaattagca gaatatcaaa tctctatgat cagcggaacg tttacttctc cgattgatca
    24781 cataaaaggt gtcgaaaatc gcaaaaaatc agaaaaatgg gcgcaaggct tgattgaaga
    24841 agctcgacaa aatcctgtgg ctggaaaaga aaatgtggca ttatatgctt ttgccaatgc
    24901 cacagattta gatggtcagc ttttacctct ggaagtggca gctgttgaat tattgaacat
    24961 catccgtcca acggttgctc taactgtgtg ggcggcattg atgggacatg cacttttcag
    25021 tagaccagat ttgtatcagc aattaaaaaa tgacttttcg acgttacaag atccgtttat
    25081 tcaagaaatg agacgctatt atcctttctt cccaatgcta cctgcgattt cgctgaaaga
    25141 agtagaagta gatggttatc gtataccaga aggcagttgg gttattttag atttatatgg
    25201 aacagaccat gatgaacgaa cagttgaagc gccagattcc tttatgatca aacggtatgt
    25261 agggaaagca aaagatattt cctataaaga agaatatgag atgattgcac aaggcggggg
    25321 aaattttcga caaatgcatc gctgtgcagg agaatggatc actcttcata gtctacgtgt
    25381 gttttccgat cagctagtaa ataagtttga gttctctgta cctgaacaag attggacgat
    25441 tccattcaat cagtttccga cttatccgaa tagccgagcg ctactttaca agaattagat
    25501 tagcataaac ttatcgaaaa aaaggaagat caaacagtgc tgatcttcct tttttcatat
    25561 tactataaat tgataaggtc aattgatcaa aatccacgaa atgcttcatc aatggtttga
    25621 taatcttcat tggataaatg caaatctaaa gcttggacat tgtcagatac ttgctctgga
    25681 cgcttagctc caggtataac tacagacact cgtggattct tcatgtacca agctaaaaca
    25741 agttgcgcag gagtggcttg gtatctttta gcaatggggc gaagtacatc gacagcggtt
    25801 aaaatttctc tgaaacgttc tccttggaaa tctggatttc tttttcgagg atctccttca
    25861 ccaaattgtt tttcctcacc aagttcatat tttcctgtca gcaaaccgga agcaagagga
    25921 aaatagggaa caaaactgat tttgtttttt tcaagataag ggaataattc tttttcagcc
    25981 tgccgatgga tcaaactgta tttatcttct actacatcga catatccatc tgcattcgct
    26041 tctttcaatt gttctaacgt gaagtttgac acaccgactg ctcggatttt tcctgcttct
    26101 tttaattcgt gcaatgtagc aactgattca ttttttggtg tgctttcatc cggaaagtgg
    26161 atataaaaaa tgtcgatgta atcagtttgc agacgtttta gtgcatcttc caccgattgt
    26221 ttgagaaact caggagaatt atcaaatgtt cgccctttat ttggtacatg agcagctttt
    26281 gtagcgatga cgacacgtga gcgatcatat tctttttcct tcagtacctc gccaatcagt
    26341 tcttcggaac ggccgtttcc gtaagcataa gcggtatcga tcaaattgat cccgctattc
    26401 aaagctgtac gaactacttg ttttcctgtc tcatcttcca aaccgtcaaa aagattatgt
    26461 cctccaacgg catttgctcc taatccaagc tgttctgcgt agacttgtga atgtccgatt
    26521 cttatttctg ccatagctga ttcctccttt ttgtctagtc taaaacaaaa taccaaaaag
    26581 ctgaactaaa acgtttttgt gaggggaaat agtcagatat ctcttgactt tgagactggt
    26641 ttttagtagg ttataagtaa tatcgaatgt caatgaaaga gcgagtaagt ttttgaaact
    26701 ttacaagaga ggatcatcga ggctgaaaat gatctaaagt ttcattagcc taaagacact
    26761 ctggagatgg acgagtgaaa agccgtcccg cgtacgagcg ttattcgtaa gaggaaagag
    26821 aaatctttca aaattaggtg gtaccgtgta tgaatttcat tcacccttgt tcatgatgaa
    26881 caagggtgat ttttttattt acatagctaa gaaagggaga gaaaactatg agtttccaaa
    26941 gaccaaaagg aacaaatgat attttgccag gcgaatcaga aaaatggcag tttgtcgaag
    27001 aaacagcacg tttattattc agagattatc agtataatga aatgcgtaca ccgatttttg
    27061 aacactatga agtgatatcc cgaagtgtag gggatacaac ggatatcgtt tcaaaagaga
    27121 tgtatgattt ttatgacaaa ggggaacgcc atgtgacgct tcgaccagaa ggtacagcac
    27181 caatcgttcg ttcttttgtt gagcataaat tgttcggccc agagtatgcg aaaccgttca
    27241 aaacttttta tatgggacca atgtttcgct acgaacgccc tcaaaaagga cggttacgtc
    27301 aattccatca aatcggagta gaagcatttg gatcagaaaa ccctgcaact gatgtggaga
    27361 gcatggtgat ggcacttgat ttcttcaaac agttggggat cacgcaaatc cggctagtca
    27421 tcaattcatt aggtgataaa gaaacgcgtc aagcctatcg tcaagcattg atcgactatc
    27481 ttttaccttt tgaatcagag ctgagtgaag actctaaacg ccgccttcat gaaaatccat
    27541 tacgcgtatt ggacagtaaa gacaaacgag atcaaaaatt tgtggcagaa gctccatcta
    27601 tcttagatta tctaagcgag cctgctcaaa aacattttga taccgttgtt tccatgctgg
    27661 atgcattggc tgttccttat gaaatcgaca gtaatatggt tcgcggacta gattattaca
    27721 cacatacgat ttttgaaatc atgagtgacg caccaaaaat gggggcacaa gcaacgattt
    27781 gcgcaggcgg acgttatgac aatctagtgg aagaactagg tggtccttca acacctggct
    27841 tcggatttgc aatgggtatc gagcgattac tcttgactat ggaggcagag gaagtagtta
    27901 tccctgcatt taatgagttg gatgcttacg tggtcgcact cggagacgaa acaaatatcg
    27961 aagcattgaa agtggtccaa gcgattcgaa actttggttt ttcagctgac cgcgacttca
    28021 tgaaccgtaa agcaaaagcg caatttaaga cagcagataa agcgaatgcc aaattagtat
    28081 tggtgatcgg tgaagatgag cttgctagtc aaacgattaa tgtcaaagca atggcaagcc
    28141 gaaaagaaaa aagttttcca ttagaagaga tatatgaaca ttttgatgaa gtctatgatg
    28201 aaatgacttt attcgagtag gaggaaaaaa ataaatggca caaagaacga tctattgcgg
    28261 attagtttcc gaacaacaat tagaacaaac agttacatta aaaggatggg tacaaaaaag
    28321 acgagacctt gggggagtaa tctttatcga cctacgtgat cgtgaaggaa tcgttcaaat
    28381 cgtctttaat cctgaaatca acaaagaagc atgggaaatc gcggataaat gtcgcagtga
    28441 atacgtgatc gaagtgactg gggaagttag aagacgcgga gaaaatgcag taaatcctaa
    28501 aatggccact ggtgaattcg aagtgattgc aagtgaaatc gtgattttga atcaagcaaa
    28561 aaccccgcca tttcaaattg aagatgatca agcaatcagt gacgaaatac gtttgaaata
    28621 tcgttatttg gatctgcgtc gtccaaaaat gactaaaaac atcaaattaa gaaatgcgac
    28681 aacaaaagcg attcgtcatt atttagatga taatgacttt ctcgatatcg aaacacctta
    28741 cctagggaaa tctacaccag aaggcgcaag agactaccta gttccttcac gtgtccatgc
    28801 tggacatttc tatgcgttgc cgcaatctcc tcaattgttt aaacaattgc tgatgaatgc
    28861 tggattcgac cgttattatc aaatcgttcg ttgtttccgc gatgaagatt tacgtggaga
    28921 ccgtcagcct gaatttacgc aagtagatat tgaaacaacg ttcttaacag cagaagaaat
    28981 ccaaacttac acagagggat tgattgcgaa ggtaatgaaa gaagttcgcg gtatcgaagt
    29041 cacattgcca tttcctcgta tgacctatga tgaagcaatg gctcgctacg gcagcgacaa
    29101 accggataca cgttttgata tggaattgat cgatctaagc gatacagtca aagaagtaga
    29161 attcaaagtc ttccaaatgg ctcttgaaaa cggcggtgtc gtgaaagcat tgaatgctaa
    29221 aggcgctgca gatcgctact cacgaaaaga catggatcag ttaggtcaat atgtaggaca
    29281 attcggagct aaggggcttg catggctgaa agtagaagaa gacggattga aaggtccaat
    29341 tgctaaattc atgggagaag caacagaagc aatcattaaa gcaacagatg caaaaccagg
    29401 tgacttgctg atgtttggcg cagataaaag tgaaatcgtc gctgctgcat taggtgctat
    29461 ccggacacgt ttaggaaaag aattaggact aattgatgaa tcgaaattca atttcttatg
    29521 ggtaactgat tggccacaat ttgaattttc agaagaagaa ggtcgatatg tctctgctca
    29581 ccatccattc acgatgccaa aagaagaaga tatcccgtta ttggctgaag accctgcaaa
    29641 agtctatgca gaagcttatg atatcgtctt gaacggttat gaactaggcg gaggttctat
    29701 ccgtattcat actcgtgagc ttcaagaaaa agtactagaa actctaggct ttacaaaaga
    29761 acaaatggaa gaacaatttg gtttcttgtt aacagcttta gattacggat tccctccaca
    29821 tggcggtatt gcattaggat tggaccgttt tgcaatgtta ttagccggag aagataatat
    29881 tcgtgaagtc attgcctttc ctaaaaacgg aaaagcagca gatgtgatga gtgatgcacc
    29941 aagtatggtt tcgcctttac aattgttcga attgaatatt gatgtaacga atatagaaga
    30001 atagccgata aaaaggtaaa aaggatttgt cgaatacgct tcttttgaca accttgattt
    30061 aattgaaaaa cactttataa tgaagccata acatataaag cggggctttt ccatgaaaaa
    30121 aacattcgaa aattgggctt atcatgatta cacgaccaag ctttcggtat ctatcgttta
    30181 tgcgttgatc gcatcagtcg cattgaattt cttttatcag ccaggacata tttattcaag
    30241 tggtattact ggtctagctc agattttgac gactttgtca aaatcactga taggattcga
    30301 agtaccggta tcaacaactt tgtatttact gaatatacct ttgtttgtat tggcgtggtt
    30361 aaaaatcggg aagaagttta caattttcac ttttatcaca gtcactttga cctccctttg
    30421 tatccatatt ttaccggaaa cagtcctatc taccgatcca atcatctgtg cgttgtttgg
    30481 gggggctgtg atgggactag gtattgggct agcgttgaga aacggcctat catcgggcgg
    30541 tctagatatc gtgagtatca cgattcgtaa aaaaacagga aagtcgattg gttctatttc
    30601 gatctacttc aatgcattga tcgtttttgt tgccggaatt ctatttggct ggcaatatat
    30661 gttttacagt acgttgtcta ttttcgtcag tggaaaagta actgatgtcg tttatactaa
    30721 acaaaagaag atgcaggtaa tgatcgtaac gaaacatcca gaaaaagtag taaatgaaat
    30781 ccaaaactgt atgcgtagag ggatcacgat catcaatgaa gcagaaggtg cttataagca
    30841 tgataagcag acagtattga tgacgatcgt tacacgatac gaactgcctc tacttagaga
    30901 agcaatgaaa gcttctgatc cacaagcttt tgtaagtatt gcagaaaacg tccagatact
    30961 tggtcgtttc tatgaggatg gcatttagat cgagtttgac aaaaattcat gaaatactgc
    31021 tgtagacaga cgttcgtttg tctgcagttt ttttctacca tagtagaatc agcaaagaaa
    31081 aactgctttt ttatttgaaa ttttcttaaa gttgaaaaaa agcatgttta tttttttaaa
    31141 tttatgggat gatagaaaaa aatagtagag aaaggacacg attctacttg ctattttcac
    31201 ttaatacccg tatattacga atgaaaaaag tttatgaaaa gttggaatat tgaatggaaa
    31261 aacaaaaaag gttaaaaaac agccgctaca tcactgggtt tgatgggctc cgttcattag
    31321 ctgtggtggg tgttatcttc tatcaccttc tgccaactag tatgaaaggc ggctatttgg
    31381 gcgttccgat ttttttcgtc gtatctggtt atttgatcac ggatctgctg cggcaggaat
    31441 gggaacaaaa tggaaaaatc aatatttggc aattttatgt cagaagaatg aagagactct
    31501 atccggcact tgtttttatg cttgtgacag cttcggctta tatcactttg tttcagcgag
    31561 ggctgttaaa caatcttcga ggagttgtgg tcagcagctt actgtatgtc aacaactggt
    31621 ggcaaatcaa taacggttta tcttatttcg atcgatttgc taatgagtca ccgtttacgc
    31681 atatctggtc tttagcagta gaaggtcaaa actatttggt ttggccgatc ttgtttgtat
    31741 tgttgatggt atttgttcgt aaaagaaaat ggatctttta tactgtgtta ggtacatcct
    31801 tcctctccgc catcttgatg atgatcttgt atacaccagg aggcgatcca acccgtgttt
    31861 attacggtac cgacactcgt ctgttttcta tatggttggg aagtgcgctt gcgtttgttt
    31921 ggccaagtac gcgtttaaag aaaaacatcc cgaaacaagc gaaaaatatt ctgaatatcg
    31981 ctggaggaat ctcgcttttg gcactgattc tttgcttctt ctttttagat gatcattaca
    32041 atttcatcta ttacggagga atgctcctag tgagtctgtt atgcgtagtg ctagttgcag
    32101 tgacagcaca ccccggagca agtttgaatc gatggctgac aaatccagta tttacttgga
    32161 ttggcaaacg aagctatggc atttatctgt atcagtttcc agttatgatt ttttatgaag
    32221 caaaggtgac tgatattgcc gatcatgttt tgttgcatac tttagtggaa atcacattga
    32281 ttctaatcat cagtgaactt tcttatcgat atgtggagcg tccgctagca cgttttgatt
    32341 atggtcgtac attccaagtg atgaaaggat ggttcagcaa accgatcatc agtaagagca
    32401 aaccatgggt tgttccaggc acattacttg tagcaattgc actcgttggt ttcgttacgg
    32461 caccgaaaaa cgctgtaaca gccgatcaaa aacaactgca ggcaaaaatc gctgaaagta
    32521 aaaaattagc agaagaaacc agaaacaatt cagaaaacac cactagttcg gttgaccaag
    32581 cgatccttga taagtacgag ttgtccaagg cacaagggaa taaggcacaa aaattagaac
    32641 taacggcatt tggtgattca gttatgttgg atgctgcaac ggatctacaa gaactttatc
    32701 caaaagtagt ggtagatgga gatgtcggac gacaattata tgccagtgta ccgtacattg
    32761 aaaaattaaa ggaacaagat ttgttgaaag acactgttct gatcggacta ggaacgaatg
    32821 gctcattctc ggaagctcag tttgatagtg tgatggatgc aatcggtgat cgaaaagtat
    32881 actgggtcaa tgtccgagta ccgacgaagc gctggcaaaa tgacgtgaat gcgatgcttg
    32941 aacagatgac gaaaaaatac gacaatatga cgctgattga ttggtacagc tacagtaatg
    33001 accatagtga ctggttttat gatgatcaag tccatccaaa tcctgaaggg atgacacatt
    33061 acattcactt agtcagcgaa gccttgctag gaggaagttc aagtacgaac agcagtgaga
    33121 caaacgtgac agaatgatag ctacaaaaaa cttcaggcaa aaacatttgt ttttgcctga
    33181 agttttttta tatttaccgt gtttttaaca ttcatataga ttcaggaagc aaaacggttg
    33241 agtgtgtctg taaataacgt tctttttgtt ttcgggtgag ttttttgaat gcagcttctg
    33301 cttttgttgc ttcgcttctt gaagaaaata cttctgcatg gatcatctta acaggtcttc
    33361 ttttttgaag acgagtatat ttagcaccag taccattgtt atgttcctct aatcgtctag
    33421 aaagatcggt tgtatatcca ccataaaatg tctgatcttt acagaataat acgtaaaaat
    33481 aatgttcatt tgccatagag catctcacga atctctgcag tgtattctcc atccatattg
    33541 taagtgatca atggtggagc gactttgaat ccgtctaatt tgccttcttt gattccttca
    33601 actaacaaaa tatttgcctc ttttccaggt tttgggtaaa caaattggat ccttttaggt
    33661 gcaattcgat agtcttccat gacctgaatg atttctaaga accgatcagg acgatggacc
    33721 atagtaaagc gtccatttgt ttttagtagc ttacttgaaa tatcgatcac ttcttctaac
    33781 gtcgtatgaa tctcatgacg ggcgattgcc aggtgtttat tagggttcgt tttatttgtt
    33841 ggcagccctt tgaaataagg tggattacag acgactaagt cacaagaatt atgtcgaacg
    33901 acagataagc tgtctttcag atcgatggtg tggacagtca tttgttcatt taaatggtta
    33961 agcgcgatac tacgtcttgc catgtctgct agacgaggtt gaagttcgat agcgtcgata
    34021 gccgcctggg ttcgtttact taaaaaaagt ccaactgcgc catttcctgc acaaaggtca
    34081 acaatcttcc cttttttagg tacacgggaa aagtgagcaa gcagcacagc atctaaagaa
    34141 aaagaaaaca ctttggaact ttggataatc ttgatatctt ctgcgtataa ttggtcgatt
    34201 cgttcgtctt cgtgaagcat ggattccctc caaaatgaaa aaaatagtcg tctgtattat
    34261 actattttta ttaaaaagaa ccaaggtggc ttgtcaaacc tctatttttt atgcatacta
    34321 tgaccataag aagggaaagg aagagactat gttttatcga tttatgcgcg gggtagttcg
    34381 agtactatta gccttagtta atggaaatgc ccgctatgag aataaagaag ttttaccgca
    34441 agatgagaat tacatactag ttgctcccca tcgtacttgg tgggacccat tatatctggc
    34501 ggtagctgca gcacccaagg aattcagctt tatggcaaaa gaagaactgt tcaaaaatcc
    34561 agttctgcga tttatattaa ctcgatccaa tgcttttcca gttaaaagag aaaatccagg
    34621 accaagcgtc attaaaacac ctgtaaagat tttgaaatcg acaaatttga gtttgatcat
    34681 gtttcccagt gggacaagac atgctacaga acttaaaggc ggaatggcat tgatttccag
    34741 aatgtctaaa gcgaaaatcg tgccagctgt atatcaaggt ccgttgacac ttggggatct
    34801 gttcaagcgt cagagagtga cagtgcgttt cggcgaacca atcgacttat cagatatcaa
    34861 gaaaacggat aaagaaggta tggcggagat cgaacgacga acacaagcag cttttgacaa
    34921 attggacaaa gaagtgaacc ctgatttcaa atatgaagtc aaaaaaaaat aaaatgataa
    34981 gtttatgcgt gggcggtctt ttgaatctac tgtcctgttc agttcagact ttttcaatga
    35041 aaacgaggga gagacgtcaa gtctgccctc tttttgcgtt ccaatatgta aaatagaaga
    35101 caggtgtcat gtaatggatc aaagtgttat aataattaga aggacatttt ttgaggtgat
    35161 tgaatgcgtt ttttacatac agccgattgg catatcggaa aaaaactaca aggttatgac
    35221 ttgattgaag accagcgtca tgtactatct tctatactag atatcgcgaa agaagaaaaa
    35281 gtagaggcaa tcgtgattgc cggagactta tatgatagga gtgtcccagc tgttgatgcc
    35341 gtagaattat acaatgaatt gatggtcgat tggaatttaa aggaaaagat cccgattttt
    35401 gctatatcag gaaatcacga tagcagtacg agactttcag cgggtacgcc atggttcagt
    35461 tattcgaact attttttgcg aacacagcta gcagaagcat ttgaaccagt cgagtttaaa
    35521 aacgtacaat ttttctttct tccttacttt gaaccaattg cagcgagatt atattttgaa
    35581 gatgacaata tccgaacgat caagcaagcg gtagccaagg tgatagataa aatgcaggag
    35641 ctatttgatt cagaaaaaaa acaagtattg attagccatt tttttgtaat gggaagtgta
    35701 aaatctgatt cggaaacgaa aatcgaagta ggcgggttgg attcgatccc tggtgaacta
    35761 cttacaccgt ttgattatgt agcactagga catttgcata atcaagctgc tttgagacag
    35821 gataatgctc gctatagcgg ttccccattg aaattctctt tatctgagat caaccaaaaa
    35881 aaaggcgtat ggatcgttga cctgacaaca ggcctggagt tgaattttag ggagatcgaa
    35941 cccctgcatg atattgaaga aataacagcg agtttcaaag aattgctgga tcctgccttt
    36001 tatcagtccg tcaatcggga gaattacatc tatatctatc tcactgatag aacgatcatc
    36061 ccgaatatga tgaaccagct tcggcaaata tatcctcgta ttttggggat tgaacgggca
    36121 aacggtcgag cagaacaaac aaagcgcaaa cgaaaagtac tagaaatgaa agatcctcaa
    36181 aaattagcag aagcattttt tagtgaaatg acggaagagc agctaactgc aaaccaagaa
    36241 aaatggctcg gagaaacgtt gcaagaaatc atggaaatgg aatgatcaag aatgaaaccg
    36301 aaaaaattac aacttaaaaa ttttggtcct tttatcaatg agaccgtaga tttttcacgt
    36361 ttgacagaag caccgctttt tttgatcagc gggaagacag gagctggcaa aacgacgatt
    36421 tttgatggga tcaccttcgc actttttggt gaaacttccg gaagacttcg ctctggaaaa
    36481 gagatgcgtt ctttgtttgc tacaccagac gaagaaacaa gcgtgacttt ttcttttgaa
    36541 catcagcaga tgagctatga aatcgaacga aaaccagaac aagttttagc aaaacgaaaa
    36601 ggaaacggaa caaaaaaaca ggcagccaaa gtaacgttga ccatttttga tgggaaagga
    36661 aaagaaataa aacaaatcac aaaacgtaca gaagcagatc agttgatcag agaactgatg
    36721 aatctcgatg cgaaacagtt ttctcaaatc gttttactac cccaaggaga attccgtaat
    36781 tttttggttt catcaagcag tgataaagag actgttttac gtcatttatt cggtactcaa
    36841 tttttccaac agttcaatga gcgattaaaa gaaaaagcaa aacaacagca acaaaaattg
    36901 gatcatttag agcaagagct gcatcttctg caaaaaaggt ttgttttagt caaagaagag
    36961 gaaccagcag cagggtttga agccgtttta gcccaatgga caaaccatca ggcaatactc
    37021 gaaaaacaaa tcacggaaga aaaagaagct ctaacggaac ttcaggaaaa acaaaagcaa
    37081 ctagaaaatt cctactatcg ttttgaaagc ttgaaaaaaa gttatgaaga aaaaacgata
    37141 ttaataaaca agcaaaagga attagctgct caaaaagacg aaatagagga aaagaaacga
    37201 tggattgggt attatgaatt tacgcaacga ttagtcgaac caatccagcg cctacaagaa
    37261 ataaaagttg aaaaaataga actgtcacaa aaaagtagtg agcaaacaaa gaaactagcg
    37321 atgactacgc agaattatga agagtggcaa aaaaatgaag caaaccgcgt acgccgacaa
    37381 acaaaaatca aagaagctgc tcaaaaactg caaaacaaac agatgatggt gccaattgtc
    37441 gaatccttac gtagtaaaaa acaagacgca gaacaattaa caatttcatt ggataaagaa
    37501 gaattgaatg ccgagaagct gtatcaaaat ctcgctatct atcaggaaag aactcgaatt
    37561 cttcaagaaa atttactgga tcaggaaaaa ctgcaagaag atcgtcttgc ttttggacag
    37621 ttaaaatatc tagatgaaaa gcagcaagaa atagaaaaac aaaaagcaaa agacactggg
    37681 tcgctcgcac agataagaga agaactcaaa aaagcaactg aagaaataac aaaaaatagt
    37741 cagctattga aagaacagac agaacaagca gaacagctga aaagccaatg ggcaaagcag
    37801 caaattgctc gtcttcagct ttttttgcgt ccaggggagc catgtcttgt ttgtggatca
    37861 acggaacacc ccatacaaca attaaaacac gaacagccaa ataaggaaga tatcttaaaa
    37921 gtagaacaac aactggcaga agctgagtct gctgtagaaa gaactcagca aatcattgcc
    37981 aaaagtgaag cacatgaaaa taatcttcaa caacaattat cagatttaga acaaaaaatc
    38041 atggcaacga atatacaatt ggctgaacaa gaagaacact tgcaacaggc tttgaaaaag
    38101 gcatttcctg agataacaga acaaaaaaca aaaacaactc ttgtagtaat cgaacaatct
    38161 ttagatagac gaaaaagcaa gatggccaat gcaagaatag agctggaaga aataagacaa
    38221 caagcagaaa agctcgaaca acaattagct gtctacaaac agcagcagac agaaaaaaat
    38281 aatcagctcc agcaactgca aggagaaatc aaaagtttag aacaacaatt gcaagatacg
    38341 gatagtaact gtttagaaga ggagatacga cgacttgaaa aacagttaga agaagactcg
    38401 aatcaactag ctgttgagca gaaagcagga gtgcaattgt tgcaagatct tcatacgctt
    38461 cggacacagc ttgatcttca acatgaacaa atagaaaaaa tagatgaaaa aatagaaaag
    38521 gaacaagaaa gaatagctaa aaagttagaa agccagtcgt atttttcaac aattgaagaa
    38581 atctgtgcat ttgcacaaca gcaagcacaa tataaagaaa accaacgtac agttacttct
    38641 tatcatgaag agcaattagt gacagctgac cggctgcgtc aattagaaaa tatccagcta
    38701 actgagacat tcccagatac agaagagatc agccaacagt tagaagaaat aagacgtatg
    38761 atcgaaataa agcaagaaaa gatatacggt ttacaagaac aaaaaattag taatcaaaaa
    38821 atctacgatg aatgtctttc gatttatcac acaagccaga cgaaattaga tgagcttacg
    38881 caattacagc agctttcgca aacattcaac ggagaaaatc ctaagaagac tagtttggaa
    38941 cggtatgtgc ttcaggttta tcttcaagaa gtgttacaag tagcaaatga tcatctccaa
    39001 cgtttaacga aaaatcgtta tcaatttgag ctagcggata ccattggcag ttatcgaggg
    39061 aaaaccggat tagaaatcaa tatctatgat gatcaggcag gtatgtctcg aagtgcgcat
    39121 accctgtctg gcggtgagag ttttattgca gcactttctt tagcattagc tcttgccgat
    39181 gtgatccaga cacaagctgg tggtgtagca atcgatgcat tgtttattga tgaaggattt
    39241 gggtcattag atgaagaagc tttggaaatg gcaatggaag ctttagaaac gatcgaaagt
    39301 gaaggaagaa tgatcggcat cattagtcat gtaagagaat tgaaagaacg agtattacaa
    39361 caaataagaa ttgatacaga aggtagcgga caaagcaaaa tacgctatca acttggataa
    39421 aaagggagat tggtaactat gaaatggagt attccagaaa aagtcattgc acgtggacgt
    39481 caatacttgc aagaaggccg agtgttatcg gttgtccctg accaagaaga aaacgtgtgg
    39541 catgcagaag tcttgggcag tgaattgtat atggttgatt tggatggtac agcaaaagag
    39601 atagattact gccaatgtcc ctattgggag gaacataaat attgtaagca tacagttgct
    39661 gtggaacttt atttacggtc gaaaaatcta tctcgtatca tgaaaaaaga ccagccaatg
    39721 ctagaaccgg taaaagcaac aagtgaggga gaaatcattg caaaaggttt ttctcgtcta
    39781 aaaacacaaa acaatcctca agcggtgcaa cctttgatta ttgaatacca agtagaaacg
    39841 attgagacta atcagtatca cccagagctt tctattttgg cactttactt gcgtatcggt
    39901 tcattggcat caccgaaaaa aacatatatc gtaaaaaaca tctatgattt tttacaagct
    39961 tacacagaaa aagaaactta cactgttaat aaacagtacc agtttcgtct agataaacgg
    40021 gcgtttcaaa aagaagatca aaaaatactc acgcatcttg caggaagtgc tcagacgcat
    40081 caattattag gtacgaacgg cttacaagtc aaaggaaaac tagataaaag atatctgctt
    40141 ctcccagtag aacaagcccg cttcctgtta gagcagatga atcagactac acgtttgcat
    40201 ctgcagataa atgaacaaaa cgatcaagga atacaatttt ccgatcaaaa caaaccttta
    40261 tcattcaaag tggaaaaatt tggagaagat tatttgctgc aagcattgaa tgattttgat
    40321 tttttcttta tgcattatca gtggggagtt atccaaggga cattttattc tctgacgaaa
    40381 tatcaacaaa cggtttatca aacttggaaa caattgattc gccgattgga gaaaccagaa
    40441 gtagtgttca agaaaaaaga attaccgtct ttgtttaaag agattatccc tctgctgtca
    40501 gagatcggcg acgtagctat tgcccctgca gtagaagagg aagtagcaga tatccccgtc
    40561 gaatttattt tctttttccg aaaagcaaaa ggaaaaatcc aagctcgagt cgatttcgtc
    40621 tatggcgaag tcatctattc gactgacccg aagcatgagg tctcgacaga acaggctttt
    40681 caggtgttac gtgacacagt agaagagaaa cgagtacttg atctattcag aatgtatcgc
    40741 taccagaaaa atgaaactgg ttatgaacgt ccattgccaa gcggggaaga actatatgcc
    40801 tttttccgca cagaactatc tgtcttccgt cagtttggtg aagtcagact tggaagaaaa
    40861 ttgcgagagt tgtatttaga tgcgcataaa catcaaccga aaatcgaagt aaccgagacc
    40921 ggttcatggc tcgatattcg attcgatgtg acagggatag aggagcaaga aatcgatcat
    40981 gtcctgcaaa gcttgctgag aaatgatgct ttttatacat tagaaaatgg tcaggttctt
    41041 tcttttgatt cagaagaatt tcaacaaaca agccaagtgt tgcaacaatt acgggaatcg
    41101 atacgtacag aagaaggaac gatccatgta cctaaaaatc aaggattgat cattcaaaat
    41161 caattggaaa aaagcaatgc tacttttagt gaatcgttcc aaacgatggt acaagatctc
    41221 attcatccag aaagatacca ggcacagctt cccaaaggat tgaatgcaac gatgagagat
    41281 tatcaaaagc aaggttttcg atggttgaag atgttaggtc attatcagtt tggcggtatt
    41341 ttagccgatg aaatgggact tgggaaaaca ctacagacaa ttgccttttt actttcggaa
    41401 aaagaagaac ggaaaagctt ctctgctttg atcgtagcgc ctgcgagctt aatttacaac
    41461 tggcaggcag aggtgagaaa attcgcccct tctttaagta tccaagtaat caatgggaat
    41521 aaaaaagaac gtgaagaatt actggctaaa gacacagata tccgagtgac ttcttatgcc
    41581 agcttaagac aggatctagc taattatcag tcgcaaaaaa ttgattattt gattcttgat
    41641 gaggcacaaa tggtcaaaaa tagcagtacg aaaactgcac aagcattgag agaattagct
    41701 gtacctcagc ggtttgcact gagtgggaca ccaatcgaga ataatttaga agaattgtgg
    41761 tcattgtttg caacgattat gccaggattt ttcccgacta aaacaaaatt cagggaactt
    41821 gccgcagaag aaattgcgca aatgattcga ccgtttattt tacggcgaga taaacaaact
    41881 gtgttgaaag acttgccgga aaaaacagag atgaatctat attctgcact tacagaagaa
    41941 caaaaaactg tttatttagc ttacttgcgt caaatgcgtg aagaaatcac atcaatggat
    42001 tctgaagcat tcaagaaaaa ccggatcggg atacttgctg gtctgacaag actgcgacaa
    42061 atttgctgcg atcctcgtct gtttattgaa gattaccaag gcggttccgg caagctcgaa
    42121 caagtaaaag atctactggt agctgccaaa gagaacaaac gaagagtttt gctgttttct
    42181 caatttacag ggatgctgac tatcttgcaa gaagagttag ccgagctagg gatctcgaca
    42241 ttttatttaa gaggcagtac gaaaccacaa gatcggttaa gtatggtaga cgcatttaat
    42301 gctggcgaaa aagatgtttt tctgatttcc ttaaaggctg ggggaactgg attgaatctc
    42361 acgggagcag atacggtcat cttgtatgac ctttggtgga atcctgccat tgaagaacaa
    42421 gctgctggac gtgcacatcg gatcggacaa aaaaatgtgg tagaagtgtg gcgtatgatc
    42481 tctgaaggaa cgattgagga acgcatggat tcactccagc aagaaaaacg cgaactgttc
    42541 caaaaagtga tccaaggtaa tgaagaacag ttgacgaaac tgactgaaga agacatccgc
    42601 atgattttaa gtgtaggaga aatcgaggag taagagactc gaaaaagcgt tcagtaatgg
    42661 gtaagaaagc ctttctaaag aagcgattgt ttatttgatt taaaaaatag caaggaggct
    42721 gggattccat tttatcccag cttccttgct atcatttttt tatttctatt tttaaaggtt
    42781 atacaaagat tgtcttcatt gtctctaaca gctgatcaaa agaagaaatc tcgatatcgc
    42841 aaattggagt ctgttcaatt ttgcgttctc gatggttgaa ccaaagcgct tgccagttag
    42901 cactttttgc acctagaaca tcattgtcgt aattatcgcc aacgtataag gtctcttctg
    42961 gaagcatatg aaattctttc tcagctagct gaaaaatctc tttttctggt ttttggaaac
    43021 ctgttgcttg agaaatgagc atattgcggg aaggaatcca attgttcaat tgaagttgct
    43081 tcagtttttt tgtctgatgg tcagtcggcc catttgtgat aattcctaat gggacattct
    43141 tttccttcaa gaaatcgagg gtttttttga cctcctcatg caagcagata ttatcaagtt
    43201 cttcctcgta aattttttga aataagaggc catcttcttc cgtaatatga gggtagtcta
    43261 aatcttttag tgattggctg atccgatgtg ctcgcatata ttctagtgtc caatctcctg
    43321 ccattacttt tgggaagttt tcatcactat gatggcggaa ccggatatat agtggatgca
    43381 tatctgcatc tgaaacaagc ggaacgactc ttttgaccgc gtttcgaaat ggctgctgct
    43441 gatcatacat cgtatcatca acatcaaaca caactgattt aatcaaaatt ttacacgcct
    43501 ttcggttttc attgattttt tcacaaatcc ttgactattg taacagaaaa aattgtctaa
    43561 aaaagctgat aaataaaggt ttttcttact atatttctat ttccttgaca gaataaggtt
    43621 tttatatttc agtttttttc actaaaaatc gtgaaacacg tcaataagtt tgatgaacaa
    43681 attaatcatt atggtagaag tcgattgatt tattttaatg caatctctgt ggaattttcg
    43741 aaagatttat tttt
//
LOCUS       DAZKPE010000018        42818 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000018 DAZKPE010000000
VERSION     DAZKPE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.018"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            214..498
                     /locus_tag="ACG930_001067"
     CDS             214..498
                     /locus_tag="ACG930_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFQ0518240.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(815..1198)
                     /locus_tag="ACG930_001068"
     CDS             complement(815..1198)
                     /locus_tag="ACG930_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFQ0518241.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(1200..1784)
                     /locus_tag="ACG930_001069"
     CDS             complement(1200..1784)
                     /locus_tag="ACG930_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFQ0518242.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="ACG930_001070"
     CDS             complement(1831..3306)
                     /locus_tag="ACG930_001070"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFQ0518243.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="ACG930_001071"
     CDS             3487..3798
                     /locus_tag="ACG930_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518244.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="ACG930_001072"
     CDS             complement(3913..6249)
                     /locus_tag="ACG930_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFQ0518245.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="ACG930_001073"
     CDS             6391..7059
                     /locus_tag="ACG930_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0518246.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="ACG930_001074"
     CDS             7062..8105
                     /locus_tag="ACG930_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0518247.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="ACG930_001075"
     CDS             complement(8342..9223)
                     /locus_tag="ACG930_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0518248.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="ACG930_001076"
     CDS             9382..10110
                     /locus_tag="ACG930_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFQ0518249.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="ACG930_001077"
     CDS             10266..10583
                     /locus_tag="ACG930_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0518250.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="ACG930_001078"
     CDS             10576..11184
                     /locus_tag="ACG930_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFQ0518251.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="ACG930_001079"
     CDS             11239..12030
                     /locus_tag="ACG930_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFQ0518252.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="ACG930_001080"
     CDS             12168..12656
                     /locus_tag="ACG930_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFQ0518253.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="ACG930_001081"
     CDS             12707..13579
                     /locus_tag="ACG930_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFQ0518254.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="ACG930_001082"
     CDS             13755..14117
                     /locus_tag="ACG930_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0518255.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="ACG930_001083"
     CDS             14126..14878
                     /locus_tag="ACG930_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518256.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="ACG930_001084"
     CDS             14892..16694
                     /locus_tag="ACG930_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518257.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="ACG930_001085"
     CDS             16971..18011
                     /locus_tag="ACG930_001085"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0518258.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="ACG930_001086"
     CDS             complement(18063..20207)
                     /locus_tag="ACG930_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0518259.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="ACG930_001087"
     CDS             complement(20564..21937)
                     /locus_tag="ACG930_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0518260.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACG930_001088"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACG930_001088"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFQ0518261.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACG930_001089"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACG930_001089"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFQ0518262.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="ACG930_001090"
     CDS             complement(23385..24398)
                     /locus_tag="ACG930_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFQ0518263.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="ACG930_001091"
     CDS             complement(24479..25078)
                     /locus_tag="ACG930_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFQ0518264.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="ACG930_001092"
     CDS             25264..25965
                     /locus_tag="ACG930_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518265.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="ACG930_001093"
     CDS             25975..28686
                     /locus_tag="ACG930_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFQ0518266.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="ACG930_001094"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="ACG930_001094"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFQ0518267.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="ACG930_001095"
     CDS             complement(30825..32006)
                     /locus_tag="ACG930_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0518268.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="ACG930_001096"
     CDS             32258..33781
                     /locus_tag="ACG930_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFQ0518269.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="ACG930_001097"
     CDS             complement(33850..34578)
                     /locus_tag="ACG930_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0518270.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="ACG930_001098"
     CDS             complement(34591..35871)
                     /locus_tag="ACG930_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0518271.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="ACG930_001099"
     CDS             complement(36012..36614)
                     /locus_tag="ACG930_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFQ0518272.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="ACG930_001100"
     CDS             36859..37065
                     /locus_tag="ACG930_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518273.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="ACG930_001101"
     CDS             37377..38096
                     /locus_tag="ACG930_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFQ0518274.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="ACG930_001102"
     CDS             complement(38177..38860)
                     /locus_tag="ACG930_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFQ0518275.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39079..41265
                     /locus_tag="ACG930_001103"
     CDS             39079..41265
                     /locus_tag="ACG930_001103"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFQ0518276.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            41611..42021
                     /locus_tag="ACG930_001104"
     CDS             41611..42021
                     /locus_tag="ACG930_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0518277.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            42035..42391
                     /locus_tag="ACG930_001105"
     CDS             42035..42391
                     /locus_tag="ACG930_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0518278.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        13949 a         7532 c         8563 g        12774 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttattt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaaggaaa aattttcaga
    38941 aaactaaaat catatcgctt cccattttca tttttagaaa ggtctgttag tataaagaaa
    39001 aaatagacaa cgaaacttta aataaccaac ttgaaataaa caaattcaaa gaagaaagat
    39061 gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc gattacaaaa agaattgaaa
    39121 cgctgggaga acaagtataa aaagcttcaa caagtctttc ggctacaaga agaaatcatt
    39181 gctacctatg aagcggctta tggcgaagca cccggactta ttgaggaaga agtacaagta
    39241 aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg agaaacgttc ctataatcgc
    39301 ttcaatcaag aacaaaaagc agctatcaca tatgatatga agaaacatct tcgaatcata
    39361 gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa aagctgttta tctgatgacg
    39421 caaaaacaag tagacgaaga acgcatacta atgatcactt ttacaaggaa cgctgcaaat
    39481 gaactaaaaa aacgagtaga taatttcagc cagagaaaaa ccgctgtcca tatcggaaca
    39541 ttccatagta tcttttttag gatatacaat gaaatttgtc gaaaatttcc tgaagtagca
    39601 atgcaaggaa tacaaggaga cttttcaaag gatactgcac aaaaagtgaa tgctgttttg
    39661 caacagctga tacgtaaata taatctttat atatttgatc aatatggaga aaaaacgatt
    39721 gcttctcggt tagactattg gcagaatatg aacctttcag tagaagaaat ggttcagtta
    39781 gttaaagaaa aatatgattc cattgataag aatgcacgac agccgatatc agaacgactg
    39841 tatggattgc tcacggaact ccaagaacaa aaaagaagcc agcaattgct agagttcaat
    39901 gatgtactcc aaaatctgaa aagcgctttg gagaatgagg agatccagca ttatatcggc
    39961 caaaaatatg attatctatt cattgatgaa tttcaagata ctaatccact tcaatgggaa
    40021 atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga ttgttgttgg agatgatgat
    40081 cagagtatct atggattcag aggatcagag ccagcataca tcaagaactt tgaaaaagaa
    40141 tatcctacca aaactctttt cttattaact aattatcgtt ctcgggcagc tattgtccaa
    40201 ggagcaaata gattgatcag ctataataaa aatgatcgga taccaaaggc gatgattcca
    40261 gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt ctgatactaa agcagaaagt
    40321 cagtggctaa tcaaacaaat tcagacattt attcaaaaaa atgggaaata taaggaatca
    40381 atcatattat accgatcagc ttcacaaacg cagcagcttg tccaatctct gctgaaaacg
    40441 aatattcctt ttgtactgga agcagatagt ccatatgaag gtatctttgg tatcaagtct
    40501 ttccaacatt tctatcaaaa aattgttcat tggcaaacag cactgaatct gcaaaagaaa
    40561 aatcaggcct accagcaatt gctccggcag ctgatggcag actgctacct gaaaaaaagt
    40621 gaatgcgatc aatacttttc tcctaaatat caaaatatag ccgttgcaga ttatattttg
    40681 tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc gagagtttga ggaagcgttg
    40741 cgtaaaacag accagcatca agaaatctat tcgcttgttc aaagctatct tcatctgcca
    40801 cgtatagcta aggaaatcga ccagagtgat caagaatgga tacgagaaga agtaaagcag
    40861 catgctactt tcagaagact ccaagcctta tcgcaagaaa cccaagcgac agctaaagaa
    40921 ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg atgcactatg tatccagagc
    40981 attcacaaaa gtaaaggtct tagttaccga aatgtctttt tgattggttg taacgaagga
    41041 agtttgcctt ataacggagc gacagaaaag aaagtaatcg actttaatga aataaaagca
    41101 gaaccagtaa cgacgataga agaagaacga agactatttt atgttgcgat gactagagca
    41161 agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt caagaaaatt gaaagtatcg
    41221 agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa agtgatagaa gagagggtgt
    41281 gacagaagtg gtcagtttca agaaagaaga aggaatgtac gaaaattgct tctcaaattt
    41341 ttgtgaaatt tcagcttatt ttcgaagaag ctatttctgg aacacagttt attcggaaaa
    41401 gggaggtgtg acaagaattt tgtcacacct cccttattta ttttgaaaat gagaatacta
    41461 ttatcaaaat agagaatata tagaaaaatt ctcattattc aaacgtaaat aatcagttat
    41521 tttgattttt tttatatttt attagctaat aattggtatt ttaaaagaaa ttactgtaga
    41581 attggattat aattaaaaag gagtgagaaa atgataaaag tatatacttc gcctagctgt
    41641 acttcctgta gaaaagcaag agcatggttg caagcgaatc aacttgaatt tgaagagaag
    41701 aatatttttg ccgaaccgtt aacagaaagt gagatcaaaa agatcttggc agcgactgaa
    41761 ggaggagttc aagatattat ttccactcgg tcgaaaattt acgaaaagct gggcatagat
    41821 tttaacgaat taactttaaa gcaaatgatc gtcttattca aagaatatcc ttcattattg
    41881 agacgaccta ttttgattga tgaaaaaaga atactaatcg gatttaatga agatgagatc
    41941 cggtcatttg tccctcgtga aattcgatgt gttgccagaa atctgatcta tttacaaaac
    42001 aataacatct taaattcata gggagggagc cttcgtggaa gtgaaagtct atggatcagc
    42061 gcactgtgta acaagtctga aggcgaaaca atggttagaa caccatcaat tgccttatca
    42121 atttgttgac ttagaagaac gcgatttaag tacagaagaa gcagaagaat tatgcagttt
    42181 tgaagaagtg caagcagaac agctatttgc gacttggtct gaggcttttc acaacattgc
    42241 gattgacctt tcctgtgtag gaaaaaaaca actgattttt ttatgcacac aacataccaa
    42301 tctcctcaga cgtcctttga ttattatcga tgaagttcta tttattggat acaatgagca
    42361 gttgatggaa cagcttatct taaataaata gactttaact gttttaatca agtcactgag
    42421 catttcatac agttgtaaca gtcgaacact tagcatcaag cgtgttatgt gttctttttt
    42481 tgactttatt tttctactat agagacatgc tcaatttatg tggtcaaaat tcaaatctag
    42541 gtggggatat agagttaaaa atatattgac atgtgtaaat ttacatgata tattcatttc
    42601 tgttgtttta agtagcaaag caataaaata gtattttaaa aaacatataa aatagttgtt
    42661 gacatgttag aaatgacatg ataagataac tgagttgtta aaaaagaacc acttgtgaag
    42721 cttgattcta tcgaaaaaaa cttcaaaaaa gttcttgaca aataacaaat gataagttat
    42781 gataaatgag ttgctgtaag atttcgaaaa acgaaatc
//
LOCUS       DAZKPE010000019        41327 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000019 DAZKPE010000000
VERSION     DAZKPE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.019"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG930_001106"
     CDS             6..305
                     /locus_tag="ACG930_001106"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0518279.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG930_001107"
     CDS             378..1739
                     /locus_tag="ACG930_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFQ0518280.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG930_001108"
     CDS             1761..2021
                     /locus_tag="ACG930_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518281.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG930_001109"
     CDS             2035..2787
                     /locus_tag="ACG930_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFQ0518282.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG930_001110"
     CDS             complement(2881..3486)
                     /locus_tag="ACG930_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0518283.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACG930_001111"
     CDS             complement(3539..4513)
                     /locus_tag="ACG930_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFQ0518284.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACG930_001112"
     CDS             complement(4891..5610)
                     /locus_tag="ACG930_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0518285.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG930_001113"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG930_001113"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFQ0518286.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACG930_001114"
     CDS             7161..8558
                     /locus_tag="ACG930_001114"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0518287.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACG930_001115"
     CDS             8639..9079
                     /locus_tag="ACG930_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0518288.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACG930_001116"
     CDS             9227..9553
                     /locus_tag="ACG930_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0518289.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACG930_001117"
     CDS             9554..10303
                     /locus_tag="ACG930_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFQ0518290.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACG930_001118"
     CDS             complement(10383..10838)
                     /locus_tag="ACG930_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0518291.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACG930_001119"
     CDS             complement(11265..11540)
                     /locus_tag="ACG930_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518292.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACG930_001120"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACG930_001120"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFQ0518293.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACG930_001121"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACG930_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFQ0518294.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="ACG930_001122"
     CDS             14770..17436
                     /locus_tag="ACG930_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0518295.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="ACG930_001123"
     CDS             17800..18552
                     /locus_tag="ACG930_001123"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0518296.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="ACG930_001124"
     CDS             complement(18574..19728)
                     /locus_tag="ACG930_001124"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFQ0518297.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="ACG930_001125"
     CDS             19913..22354
                     /locus_tag="ACG930_001125"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFQ0518298.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="ACG930_001126"
     CDS             complement(22684..23388)
                     /locus_tag="ACG930_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518299.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="ACG930_001127"
     CDS             complement(23575..23820)
                     /locus_tag="ACG930_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518300.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLTVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="ACG930_001128"
     CDS             complement(23837..24688)
                     /locus_tag="ACG930_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0518301.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="ACG930_001129"
     CDS             24854..25858
                     /locus_tag="ACG930_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFQ0518302.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="ACG930_001130"
     CDS             complement(26099..26455)
                     /locus_tag="ACG930_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0518303.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="ACG930_001131"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="ACG930_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFQ0518304.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="ACG930_001132"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="ACG930_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFQ0518305.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="ACG930_001133"
     CDS             complement(30815..31576)
                     /locus_tag="ACG930_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0518306.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31743..32375
                     /locus_tag="ACG930_001134"
     CDS             31743..32375
                     /locus_tag="ACG930_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFQ0518307.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGDNMFYPDIVKMNEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="ACG930_001135"
     CDS             32434..33294
                     /locus_tag="ACG930_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFQ0518308.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="ACG930_001136"
     CDS             33479..35794
                     /locus_tag="ACG930_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0518309.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /gene="dnaG"
                     /locus_tag="ACG930_001137"
     CDS             35976..37817
                     /gene="dnaG"
                     /locus_tag="ACG930_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFQ0518310.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="ACG930_001138"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="ACG930_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFQ0518311.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39170..41269
                     /locus_tag="ACG930_001139"
     CDS             39170..41269
                     /locus_tag="ACG930_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFQ0518312.1"
                     /translation="MKKCPNCGLKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT        13542 a         7264 c         8555 g        11966 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaaattta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc gttagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatctg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttaggaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga gataacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    39121 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    39181 tccaaattgc ggattgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    39241 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    39301 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    39361 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    39421 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    39481 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    39541 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    39601 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    39661 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    39721 agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag gtaaagaaac
    39781 agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat ttactgaaaa
    39841 acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag aaatactcga
    39901 aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg atgctgaaaa
    39961 tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag aagagaacca
    40021 gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata ctgaaaaaac
    40081 acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga aaaaatcaaa
    40141 aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa gctgggctta
    40201 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    40261 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    40321 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    40381 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    40441 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    40501 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    40561 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    40621 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    40681 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    40741 tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata aagagaaaaa
    40801 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag aacaagcaaa
    40861 acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg tcgcacaagc
    40921 agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga atcagccaat
    40981 caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga cgtgggcacc
    41041 aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg ttgaaggagg
    41101 ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc tatatgccac
    41161 ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat tttacatcgt
    41221 aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat tttaggcaaa
    41281 tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaag
//
LOCUS       DAZKPE010000020        38804 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000020 DAZKPE010000000
VERSION     DAZKPE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.020"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            211..1017
                     /gene="proB"
                     /locus_tag="ACG930_001140"
     CDS             211..1017
                     /gene="proB"
                     /locus_tag="ACG930_001140"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFQ0518313.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1014..2261
                     /locus_tag="ACG930_001141"
     CDS             1014..2261
                     /locus_tag="ACG930_001141"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFQ0518314.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2337..2681
                     /locus_tag="ACG930_001142"
     CDS             2337..2681
                     /locus_tag="ACG930_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518315.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2798..3124)
                     /locus_tag="ACG930_001143"
     CDS             complement(2798..3124)
                     /locus_tag="ACG930_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518316.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3497..4699)
                     /locus_tag="ACG930_001144"
     CDS             complement(3497..4699)
                     /locus_tag="ACG930_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0518317.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4816..5331
                     /locus_tag="ACG930_001145"
     CDS             4816..5331
                     /locus_tag="ACG930_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0518318.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5530..5976)
                     /locus_tag="ACG930_001146"
     CDS             complement(5530..5976)
                     /locus_tag="ACG930_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFQ0518319.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6023..7501)
                     /gene="msr(C)"
                     /locus_tag="ACG930_001147"
     CDS             complement(6023..7501)
                     /gene="msr(C)"
                     /locus_tag="ACG930_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFQ0518320.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7855..8484)
                     /locus_tag="ACG930_001148"
     CDS             complement(7855..8484)
                     /locus_tag="ACG930_001148"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0518321.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8468..8932)
                     /locus_tag="ACG930_001149"
     CDS             complement(8468..8932)
                     /locus_tag="ACG930_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0518322.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9419..10687)
                     /locus_tag="ACG930_001150"
     CDS             complement(9419..10687)
                     /locus_tag="ACG930_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0518323.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10918..11655)
                     /locus_tag="ACG930_001151"
     CDS             complement(10918..11655)
                     /locus_tag="ACG930_001151"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0518324.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11722..12291)
                     /locus_tag="ACG930_001152"
     CDS             complement(11722..12291)
                     /locus_tag="ACG930_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFQ0518325.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12419..13291
                     /locus_tag="ACG930_001153"
     CDS             12419..13291
                     /locus_tag="ACG930_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0518326.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13633..14505
                     /locus_tag="ACG930_001154"
     CDS             13633..14505
                     /locus_tag="ACG930_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0518327.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14502..16460
                     /gene="nagE"
                     /locus_tag="ACG930_001155"
     CDS             14502..16460
                     /gene="nagE"
                     /locus_tag="ACG930_001155"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFQ0518328.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIISGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16711..17562)
                     /locus_tag="ACG930_001156"
     CDS             complement(16711..17562)
                     /locus_tag="ACG930_001156"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0518329.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17685..18152
                     /locus_tag="ACG930_001157"
     CDS             17685..18152
                     /locus_tag="ACG930_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFQ0518330.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18415..18897)
                     /locus_tag="ACG930_001158"
     CDS             complement(18415..18897)
                     /locus_tag="ACG930_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0518331.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18997..19860)
                     /locus_tag="ACG930_001159"
     CDS             complement(18997..19860)
                     /locus_tag="ACG930_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0518332.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            complement(20357..21544)
                     /locus_tag="ACG930_001160"
     CDS             complement(20357..21544)
                     /locus_tag="ACG930_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFQ0518333.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            21932..22780
                     /locus_tag="ACG930_001161"
     CDS             21932..22780
                     /locus_tag="ACG930_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFQ0518334.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(22951..23292)
                     /locus_tag="ACG930_001162"
     CDS             complement(22951..23292)
                     /locus_tag="ACG930_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFQ0518335.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            23378..24085
                     /locus_tag="ACG930_001163"
     CDS             23378..24085
                     /locus_tag="ACG930_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFQ0518336.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            24072..24395
                     /locus_tag="ACG930_001164"
     CDS             24072..24395
                     /locus_tag="ACG930_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFQ0518337.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(24484..25521)
                     /locus_tag="ACG930_001165"
     CDS             complement(24484..25521)
                     /locus_tag="ACG930_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0518338.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(25968..26951)
                     /locus_tag="ACG930_001166"
     CDS             complement(25968..26951)
                     /locus_tag="ACG930_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFQ0518339.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(27367..28137)
                     /locus_tag="ACG930_001167"
     CDS             complement(27367..28137)
                     /locus_tag="ACG930_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518340.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(28130..29065)
                     /locus_tag="ACG930_001168"
     CDS             complement(28130..29065)
                     /locus_tag="ACG930_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518341.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(29659..31308)
                     /locus_tag="ACG930_001169"
     CDS             complement(29659..31308)
                     /locus_tag="ACG930_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFQ0518342.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(31503..32399)
                     /locus_tag="ACG930_001170"
     CDS             complement(31503..32399)
                     /locus_tag="ACG930_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0518343.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(32392..33072)
                     /locus_tag="ACG930_001171"
     CDS             complement(32392..33072)
                     /locus_tag="ACG930_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0518344.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(33073..33855)
                     /locus_tag="ACG930_001172"
     CDS             complement(33073..33855)
                     /locus_tag="ACG930_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0518345.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(33848..34765)
                     /locus_tag="ACG930_001173"
     CDS             complement(33848..34765)
                     /locus_tag="ACG930_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0518346.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(34768..35052)
                     /locus_tag="ACG930_001174"
     CDS             complement(34768..35052)
                     /locus_tag="ACG930_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518347.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(35753..36373)
                     /locus_tag="ACG930_001175"
     CDS             complement(35753..36373)
                     /locus_tag="ACG930_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518348.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(36454..36864)
                     /locus_tag="ACG930_001176"
     CDS             complement(36454..36864)
                     /locus_tag="ACG930_001176"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518349.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            36894..38072
                     /locus_tag="ACG930_001177"
                     /pseudo
     CDS             36894..38072
                     /locus_tag="ACG930_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            38249..38535
                     /locus_tag="ACG930_001178"
                     /pseudo
     CDS             38249..38535
                     /locus_tag="ACG930_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        11696 a         8051 c         6834 g        12223 t
ORIGIN      
        1 aactactcct attctaacat atccgaggct gtaaaagact ttctttacaa attcttcaag
       61 aaattctgct atcttaaagt aaaccattaa ttcgttcttt ttccaaacga ctacaagttg
      121 tacaaaaaaa ctatttttta catgacttta ctcgtcaaaa caagtagaat agaacgaaat
      181 taatgagtgg atatttgatt gaggtgtcac atgcgtaaag aaattaaaaa tgcaaaacga
      241 attattgtca aagtaggaac aagtacattg atttatccca atggaaatat caatcttgcg
      301 gcaatcgatc agttagcttt tgtcctttct gatcttagaa atcggggaaa ggaagtgatc
      361 ttagtctcat caggagctgt aggcgttggt atgcataaat tacatttgtc agaacgtccg
      421 actttgattc ctgaacagca agctgcggcg gctgttggtc aagccgaact gatgaatatc
      481 tataatcaaa gattcagtgt atataatcaa cagacggcac agatcctcgt gacaagagac
      541 gtggtagatt atcctgaaag tcgtaaaaat gtgaggaata cattggaaca gcttttgatt
      601 atggacacga tccctatcgt gaacgaaaac gatactgtag cagtggatga attagatcat
      661 ctgacaaaat ttggcgataa tgatcagctg tcagccatca tggcaaaact tgtcgcggca
      721 gaccttttga tcgtcctttc tgatatcgac gggttttatt cagataatcc gactacaaat
      781 cccgaggctc agatgtatcg ctatatcgat aaaatcgatg aaaagattct ggcacaagca
      841 ggtggtgctg gtagcacatt tggaacaggc ggtatgcaga gtaaattaaa agccgcttct
      901 aggatatttg aagcaaacag cgcaatgatt ttagcaaatg gaaaaaatcc ggcaattatt
      961 tttgatattc ttgcaggaaa agaagtaggt actttattta aggaggactt gaaatgactg
     1021 acttgatgca attaggacaa caggcaaaag atagcgcgca acaactagca cttatgccta
     1081 caaaccgcaa aaatgagcta cttgttcaaa tggcacaaac catcaaaaag aatcaacaag
     1141 cgatcattga agcaaatcat aaagacttag aaaaagcagt cgaaaacaat atcagtgaaa
     1201 cgatgcaaga ccgcttgcag ctgacacctg agcgaatcaa tgccatggct acagagatcg
     1261 aaaaaattgc ttcgttagac gatcctattg gaaaagtaga tgagatgtgg acgaacaccg
     1321 acggattgag aatcggcaaa aagcgcgtgc cactaggcgt gaccggcatc atttacgaat
     1381 ctcgtccaaa tgtcacgaca gatgcagcta gtctagcatt caaatcaggg aatgccgtta
     1441 tccttcgcgg tggcaaagaa gcattcttct cgaatcaatt attagtccaa ttattgcagc
     1501 aagtactggt cagtgctggc gaatctcctt atgccatcca gtttgtcgat gatacttctc
     1561 atgaaactgc aggacagttg atgcgattga cagaatactt agatgtgctg attcctcgag
     1621 gcggagcaaa attaatccaa cgagtcaaag aacaggcaac ggtacctatc attgaaacag
     1681 gtacaggaaa taatcacgta tatatcgata aagaagcaca gttatctatg gcagtgaaca
     1741 tcatcgtcaa tgcaaaagct tcccgtccat ctgtctgtaa cgcggcagaa acattgctga
     1801 tccattctga gatcgcacct tttttcttgc cagctattga aaaagaactg gtagaacacg
     1861 gggtctcttt acgtgcggat gctcgtgcgt tagaatatct agagacggct gctttagcag
     1921 aagacacaga ttgggatact gaatatctag attatatcct tgctgtcaaa gtggtcgatt
     1981 ctttggatga agcaattgca catatcaatc ggcataatac taaacattca gaaacgatcg
     2041 tgacagatag ttatgcggct agtcaacgtt tcttaaatga agtggacgcg gcggctgtct
     2101 atgtcaatgc ctccactcgt tttacagacg gatcggtatt tggttttggt gcagagattg
     2161 gtatctctac tcaaaagttg catgcccgtg gtccaatggg gttaaatgaa ttaacttcca
     2221 caaaatatat catttatggc gatggacaaa tccgcgaata atgtttcgtg tgaaacatta
     2281 ttcccgcctt ttgccttttt tctgtaaagg ttctatccaa ctagaaaggt gtcaatatgt
     2341 ttgaaatttt aatgattttt tttatttacc ttatttctct gaatatcgct gcttttctgg
     2401 gagtcggtat tttatccctt ttctttcaat tcaaaaaacg aagcataggg agtcaacggg
     2461 aaaaatggtc gcagtatttt gacaaaatcg ggcaaaaagg gctggttaca cgcttgcaca
     2521 ttagttacat ggttgcatta tgcttattag cgacaatcaa ttactattct tttttcgatc
     2581 attcaatcgc ttatacgatt acgctactga ttgctgggat ttttcactta tcttataaat
     2641 atcagctgaa taaaaaccac ttgaatcgga ctttccgcta aaaaatatcc gtacgataag
     2701 tagagtgcct tgaagatcgg caaaaaactg ccggactttt tagaggctgt gacaaagatt
     2761 ttgtcacagc ctctttttcc atataaacgg cgttcgccta ccagctgcct ggtaaatctg
     2821 tttcctcttc gttaagaagc gaaaatccgt caaatgtttc gccatcataa taacgaagca
     2881 gctcatccat ggacaagttc atcgtttttt ctttttcttc ttccgctgat tcagccagta
     2941 gctgttcccg atacacctga tacataccag ctattttttg ctgcatcgct tttctagttt
     3001 caccttccgc attgattatt ggcaattctt tgatatagcc acgataaatc aaccgatcat
     3061 ctgaaaattc aatgggtaat tcaacgagtg tcaacccgac ttcctgaaaa tattcttcca
     3121 gcatctatta tccccccatt ctttttctta aatgaatttt agcttaccta ctgaaaattt
     3181 tccagtttca ttattttgag aaaaaaaggg aatgtgacaa aaatcgtgtc acatcccctt
     3241 tttccgaata aatggtgttc ttctgccaac tcctcaatca taagtcacaa tattcaacaa
     3301 acatgagaaa ctgttttttg aaattgttcc ttgtgattca gagttaaacg acagtctcac
     3361 aacctcttgg taaacggcgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga
     3421 aaaatatgag aagctatttt tgtttggctg ttcttatgac ttgatgcagg acagcttttt
     3481 cacaacctct gatttcttat tcttcttcat ttgtagcaaa ataattacgg tgataaatga
     3541 tacaacatac actgataaga acaatggcac ctgcaaaata aaacgcatag ctttcaccaa
     3601 tatgttcacc aatcacacct gcaataaatg gtgctaaagc tccaccgaaa aagcggacaa
     3661 aactatagct ggacgaagca acgtttcgtt gcagacctgg tatttccata gcaatcgtcg
     3721 tcaacagtgt attgataatt ccttggaaaa atcctgctaa cacaatgctg atcggtacaa
     3781 ggactggcat agaagttcca gctcctaata acagcaaaca aataatgaat aagacaaatg
     3841 ctgctaaaat tgtccgataa gtcgtaaact tccgctcaag agccggtgca acgaaaatcg
     3901 aagcaatagc cagaagcaca ccccagccaa aaaatacaaa accgacttct aattcagaat
     3961 agccaatcaa taaaaatggc gcatacgcaa gtaaagtaaa gaatccgaaa ttatataaca
     4021 atgcgattag tccaactgaa cgaagtttat gattgcttaa cgctttgaca ccttcccaaa
     4081 ggcctacttt tctctttggt ttctcagttt caggtaaaag taccgctagg gctataaaac
     4141 cgcaaaacat caaaaatgct accccaaaaa atggataacg ccatgaacca ctgcccaaga
     4201 ccccaccgac tagagggcca acagccattc cgcagccaag tgctgcttca tacatcatga
     4261 ttgctttttc tgtgttacca actaaaatac tgacgatcgt tgctaaagca gtagagacaa
     4321 ataaagcatt cccgacaccc cagccggcac gtaacccaat cagcattccg atattcccag
     4381 ataatccgcc aagaccagcg aatacaacga tgataaacaa tcctgtcatc aatgtttttt
     4441 tcaaaccgat ccgactagat aagaaacctg taaatagcat caccacacca gtgactaaca
     4501 tgtaactagt aaataacagg gtcgtttcag ctggcgtagc gtttaactgt gcagcaatcg
     4561 tttttaagat tgggtctact agacccactc ccataaaagc gatcatacag gtagctgcta
     4621 caactagcgc tgaacttttc ccctttgttt cttcatttgt ttgttcttgt atatctattt
     4681 gattctccaa tatttccatc cctttctctc tattagcatc atacatgatt tattttacat
     4741 gtaaatatgc acatgtaaaa cgtggaaact ttactgtgat ataataaaga aaataagacg
     4801 agaggtagga tttttatgaa tactttagcc tatatattat tatgcgtgct tttatccaaa
     4861 ccacgttctg ggtatgaatt gaagcagctg atcacaattt tttgggaagc ccatcacagt
     4921 cagatctata caacgcttgc caagttagac cagcagggtt atgtgaccgt tttggacaaa
     4981 gacgagcact ctcaaaaaaa gatctaccac ttgactgatg aaggacgtgc tcttgtagag
     5041 gaatggatca aagaggaaac tcccgctcct acgcaaaaag atgaatttct agcaaaaatc
     5101 tatgcttttt cgacgctcga taaaacaaca gctactggac tgctattcac tagagaacaa
     5161 cagctgaaca aaatcatgca aaaaaatcaa aaaaaattga atgacctctc gctagacaag
     5221 aaacaagaat ttggacgtta tgttgtgatc cagcgcagaa ttatgctttg tcagcaggaa
     5281 ctccaatggt gtcagcaagt aagagaacaa atgcagcagt tttttgagta agggataaac
     5341 agaacctttc tagaaatatc tattgaagag caaattatct tcaataaaag agcaatacag
     5401 ttggaaaaga aaaagcgatc cgaacgacag gccaaaacct atcgttcgga tcactatttt
     5461 tctagaactg cattcaagag actatgacaa aaagcatgcc aaggcctttt ttcaaataac
     5521 agtgttccat cattcattac tttgaattgc ttttagcaca cttcttgaaa gcgggccaac
     5581 gatgatcaac tgcaacggta aagcggcaat cacattcatt ttccaagcat tcatataagc
     5641 agagaataat tgatcaggta ttccttgttc catgatcaca ccgaataaag acatacatgt
     5701 caccattcct aaaaccatca agcatgaaat agttaagatc atttggacct tgctttctgg
     5761 atttactggt agtttaaagg caattttttt cgccagcaca ccgatgatga agacatccaa
     5821 aatgaaagcc accacgaatc caggcactag accaatcaac aaacttgata aatgaagatc
     5881 ttgatgcagc cataaattat acgcgctcat ccccaagacc atcaaaaaac acatcattgt
     5941 tgtaaaaatt attccttctt ttttatttgt aggcaatctg taccactcct ttaaatttgt
     6001 cacgaaaatc atcgtagcac atttaaaaat ttctcgtaag tacttttttt attttctgcc
     6061 cttttatttc ataaacttca tcagccgtac gctcgacaaa gtaagaatca tgagaagtaa
     6121 acaaaatcgt tcccggatat atttgcatta gcttctctaa agcttcgatc gttgccatat
     6181 caataaaatt agtcggttca tctaacagca acacattact tggcttagta aaaagcaaag
     6241 caatcgtcag acgggtcgct tctcccccac ttaatgtaca taacggtttc gtcaaagttt
     6301 cctgagcaaa ccctaagtga ttcagcaaac tacggacaag cgattctgaa aactctgttt
     6361 gtctcatgac aaaacgaatg atggattctt cagatgtcat ttgataaccc ttttgctgat
     6421 atacttgaaa gcttactttc ggagagagaa ggattccttc tccttgtttg cggatatgtt
     6481 ctaataaggt tgtcttacct gaaccatttt caccgacaat cgcgattttt ttacctaaag
     6541 aaaactgaaa atcaccattt accagtaatg ttctcccact tctttccaat tggacatttt
     6601 gtcccatgat gggatagcgg ctgtggagtt caagagattt tggtactgga aaacggattt
     6661 gtttcatctg ctgcggcttg gttgtttctc ctattttttg gagtcttctc tctaatgttt
     6721 tcgcattctt ttggatggct ttttgtacac tgtctttttg tttagaggaa gacaaccgat
     6781 ccggtctgat ttgttgcttt ttctttttac tggacacttt ttccaacttt tccgcttgtt
     6841 ttttcttttc ttggatcgat ttttccaatc gttttttctc tttcatgatc gactctgctt
     6901 ctcgtagctg agtctttttc tccaattcct tttgagtgag ataggcacta taattccccg
     6961 aaaactctcg gatttctccg tcttttactt cccagatttt cgatgctagc tcatctagaa
     7021 aatagcgatc atgactaaca aaaaccagcg taccataata ataacgaagc tcttcaatca
     7081 gtcgatcaat actttttcta tctagatggg ttgttggctc gtctagaagc atcccttgtt
     7141 cataagaaga aagaagacgt atcaactcga tctttcgttc ttcccctccg ctccatttcc
     7201 gctctgaagt ttcttccagt cttaactgga aatgactggc taattccaaa tttaggtcct
     7261 ttgcttcagc gagataggtt aattgaggca ggtagttgaa ggtgatctct gtttggattt
     7321 tcccatgatc gggaaaaagt tcaccggcta ttagtttgag caaagtcgat ttaccgacac
     7381 cattttctcc tatgatccct atacgatctt gctgatagac acgaagagaa tcaatagata
     7441 gttctagctg gttgccaaag ctgacttgta gatttgttat atttactgct aaattttcca
     7501 tatgttttac actcctattt catgtaaaac aacaattatc gatactaaaa aagagcagaa
     7561 aaatctgttt gcaaaaaaac tgcatcacat cttttcctac tctgaacgaa ataactatga
     7621 ctaaatcacc aaatctgtca tagctttcac ctattctact gtcgttcgaa aaaatggaca
     7681 tactccatcc atgaaattgt tgtttataca tgtcttttga atttatttag ttgttattca
     7741 aaagttcgaa acgtaatttc atcgatgcag tcatttttcc gacctccttt tttattaggt
     7801 taccacacac gattcaaaaa aagcaatagc tactgaatag taactgaaaa ccttttattc
     7861 gaacgtagtg atcttttctg gtgctaaacg aacagactcg taaccttctt ctaccgcttt
     7921 tcctattgat aaaataataa ctggaacata acggtcttta tccaaaccaa atgcctctgc
     7981 caactgatct gcttcgactc caccaattgg atttgtttca tagccatgat cacgcgcaac
     8041 taacatgaat tgcatagccg ctaagctaga atcgactttg actacatcgt tcatttcttc
     8101 tcttgaaaaa ctcttgtaat aaggaatgat cgcagctaat tgttgatctc tgacttcttt
     8161 tggcatcttc cctgattcgt aagcttggtt atagatttct tcgccatatt cgtaacattg
     8221 catatcgcca aaaatcatga ccattgcaga agaagtatca ttttgtctcg tattgaaacg
     8281 gatcaaagga cgcaagattt cttttgcttc ctcgctttca gcgaccacaa agcgccatgg
     8341 ttgcatattg acagaagaag gtgcagtcgt cgcttctttg atcatttcca gcatttcttc
     8401 gtgtgggatt ttgtatgttt catcatatac gcgaacggat cttctaccag tcataattgt
     8461 tgaaaaatca tttttttgtt ccattattat taacctcttt cgtttctgtt gttatattgc
     8521 aaagttgggt attcaattta tctaaaagtg ttagaaattg tttcatttct acatcgctga
     8581 aagccgggga tagcacggaa cctgtatctt tatggtccat ttcacaatgc tcgattttct
     8641 tctgggcttt ttctgttagc gctacataca cttcccggtt gttctgagga tttctctgac
     8701 gcgaaacata gccatttgct tccaatacct tcagatgacg agtaactgct ccttgatcaa
     8761 tctgcaactt ttcttgcaaa ctgctttgta gcaatggatt ttcttctttc agtctcatca
     8821 tgatctcgta tctagtaaga cttataccga tattttcttc aaagatctgg acgatttttt
     8881 gatcggctaa tttgatttga tataaaaggt gactaatctc ttctaaagac ataatttcct
     8941 cccttctaat aattgactcg tcaacgattg acttgtcaat aatagaataa aaaaagaaaa
     9001 aagtcaaaga atcagctgtg taataaaaaa aacgctctca atagaaaagt atagagaaaa
     9061 gaaatttttt gtagaatgaa cggaaaaaat gataaagaaa gcacaacgct aaaaccaaga
     9121 ttattgattc ttatcaaact atagaagata gctcttctgc agtagaaaat tttacaccgc
     9181 caaaaatttc cgaaatcgcc ttttgcaaga atcccgtcga atattagaaa ttggatcagt
     9241 atgcttaaac agtaataaaa aagttatgac aagatgttgt cacaaccttt tttgagtaaa
     9301 cggtgttcaa aaacttgcat ctgcggtaat aagttcaacc aaacaaaaaa catgaaaatc
     9361 tgtttttgtt tggctgttct tactacttga tgcagggcag ctttttcact acctcttttt
     9421 aataaccata aaatcctatt ccttcatatc tccagcccat cggtgttagc caatctcttt
     9481 ccttagcact caaggtatag tgatgggtac cagttttttc atttggatta aatagtcgat
     9541 aaattggctt ggaaccacca gaataaaaac ttagaccttc ataacgccaa ccgatttttg
     9601 ttaaagagtt gatctcagat tgtgccattg tgtaatgatg gtctccactg taaggattgt
     9661 ataaacggta gacaggttgt ccgctgtttg gtgcttgcca agcaatccct tcatattccc
     9721 agcctacagt tggcagataa tttttttctc cggcattcaa tgtatataaa tgttctcctg
     9781 tatgacggtt atacagacga tacatcggag aagttgaagt tggtgctgta tcatactgtg
     9841 tcagattata ggtttcgatt acattgttca atgtagaacc ataattaggc gcagtggcat
     9901 aacgacctgt tagccaagcc gtagcatctt tgtaagagtt cgtattgctt ttccatgcac
     9961 cggaatagta gtaaacgcct ggctgaaaag aagtcgtctt caataccgtt acgttatctt
    10021 gcaatgattc tttgtacgaa ggatattttc taaaagcggc attcaccgta atccattgcc
    10081 cattcacata ttccgaagta ggcatcgtaa cagattggcc attatagctt cctttaatcc
    10141 caaatagatt gtaattaggg gcagaagcca aagtactgtt cccccagcca ctttcaacga
    10201 tggcttgagc aatcatgact gatgcatata agtcattggc acttgccaaa ctttgtgcag
    10261 ttgaggcaat actatcaatg aacgcttgtt gagaattagc agatgagcga gcataaaaag
    10321 catagccagt atagttttcg aattcagaca aatctgcttg atgggtatgt gtcaatgttt
    10381 gcccatctgt caattggttc gtgatttctt ctgcattctc tggattgttc tgagcttctg
    10441 ctgatgtact gtcttcggtt tgtgtttgtt ctgttgtttc agttgttggt tcttcggttg
    10501 aaattgtatt ttctgagaca gtagctgact gcaaagtact ctctgtatcg ttttcaattc
    10561 ctgtttctga agaactcgat gtctgagttg cgacagtttc tgtcgattct tcagctagca
    10621 ctgttgtgtt ggcaactgct agatttccta aaagaataac gctaaataat aaattctttg
    10681 ctttcatctt ttttctcctt tgaattatga aacttttcct aaataacagt gtaactaaaa
    10741 aagtaaaagc aagtcaatgt ccatatttaa ataacatttg tttctttttg ataaatttgc
    10801 tttttctaca taaaaagacg taaatgaaga atattcttct ccattcacgc cttaaattga
    10861 tggtcgtttg aataactatt taacaagtaa ttctctttgg atattatccg ttatggatta
    10921 tacttcctgt gtcgtcggac ggataatcat gttactgaca gacatccggt ctggcgtttc
    10981 tatcgcaaat gctacagcag aagctatatc ttcggaggtc aatccccatt ctttttgcgc
    11041 ttcatgaagt tcaagagcag cctttttgtc gctgatggtt tgatataatt cagtttgaac
    11101 agctcctgga gagatgatcg tagatttgat gttattttgc cgttgctctt gacgtaatcc
    11161 ttccatgatt gcacggacag caaattttgt tccgcaataa acggcggaat caggataaac
    11221 aacatgtccc gccacagaat cagttgaaat gatatgccca gatttttgtt tttccatgat
    11281 tggaagtacg gcggaaattc catttaacac acccatgatg ttgatatcaa gcatattttg
    11341 ccattcatca cggtgacctt caactaatgg agcggttggc atgattcctg cattattgta
    11401 caatacatcg attcgaccga acttttccat cgctaaatcg ataactgctt ggacttgtgc
    11461 aaaatctctt acatctgctg tttgaatata tagctcagct tctggtaaag attcttttat
    11521 tgcttttagg cgatcttctc ggcgtgcagc tataactagt ttagcccctt tttctgctaa
    11581 tagcttcgtt gttgcttcac cgattccgct tgaagcgccc atgatgacaa tcactttttc
    11641 tgataaatca ttcattctat tctcctcctg ttttgaaaaa tctcttgctt atactcacta
    11701 tctcttattt catcttactg ttcaaataat ccgttcgaca ggtttgacga ttttggcagg
    11761 gattcctgca acgatggtat tgtctgggac atctttcgta acagttgcat tcgctgcaac
    11821 aatggcattc tcgccaatcg ttacgcctgg cagaatagtt gctcctgctc cgatccaagc
    11881 atttttcttg atgtggattg gctttactaa caagcctctt cgttcttttg gatcggttag
    11941 atggttcacc gtgatgaggt tgacacgagg accaatcaat actgaatctt ctaaacagat
    12001 gccacctaag tcaacgaaca tcacttgacg attgataaag acatttttcc ctatactaat
    12061 atgtttgccg aaatctgtat aaaaaggcag cagaacagtc accgtatcat ctactttgtc
    12121 actaatgata ttttctagcc gtttgcggat atctgctggt tcatggtacc cagtattcag
    12181 cgctgctaaa ggctcttcgt tttcagcttg gatctgatgg atcacttcaa agagcggatc
    12241 cgttactcga atctctttat tgacgatttg tttttcgatg aggcttgtca ttttgctccc
    12301 tccttttatc cttactttat aacggacggc ttatcatgtc taatacttat aaaacatact
    12361 taactattcc ttttaactat acttagtggt atgctttttt aaaaacagga gggaaaaaat
    12421 ggatattcgt atactgacgt attttttagc agtagctaga gaaaaaaata tcagccgagc
    12481 agcaaaatct ctgcatatca cgcaacctac tctctcaaaa caactgaaag atttagaaga
    12541 agaacttggt gtgacacttt tcactcgggg ctcccgagag atacagttga cggattctgg
    12601 tcgatatctt tattcaaaag gaaaagaaat cttgtcgttg gtagaaaaaa cggcgaacaa
    12661 tttaacaaat gacgcaatca tctctggaga aatctacatt ggcggaggcg aaactaaagc
    12721 aatctctttc atttctgata gccttcattc gttgatcaag gcgcatcctg atatccagtt
    12781 tcatttatat agcgggaatg cagatgatat catagacaaa ctggatagcg gattacttga
    12841 ttttggactc gtaatcgaac cgacaaacaa acaaaaatac cagtcatttc gactgccagc
    12901 ccaagatcgt tggggacttt tgatacatcg aaatcatcct ttagcaaagc aaaccgtcat
    12961 ccatccgcag gaactgaaaa ctgttccttt gatcatttcc cggcaaacgt cagtggacag
    13021 tcaactagct gaatggctag gtttcagcat agatcagtta tcgatcgtcg gaacatataa
    13081 cttattgtac aatgcttctt tgatggtcga taacgggact tttggtgcat tagctctaga
    13141 tgggatcatc aatacttatg ggacggaaaa aatattcatc ccactcgatc cgccattaca
    13201 agcttcactg aatctcattt ggaaaaaaga ccagcctctt tctcctgctg ctcgtaaatt
    13261 tttagatgtc ctaacggaga aatacagtta agtagagttt ttttccttcg ctttcagctt
    13321 tttaacaacg aataagataa gcaaaagatc caacgattaa ataacataag tttcttaatt
    13381 tatttcttcc ttttatttct gataattcca gtaaattact ataattataa aaaaagaatt
    13441 gacaaaacat aactgtctat ataaaattga ttacgttaac aataattcgt ttcatgtgac
    13501 tagatcatac taggcatgaa aaatctctga ggaacatggt ttccctagga ggtttttcgt
    13561 gtctattttt gtttggccgc aatcaactgg tctagcaaac gtgaaaacca aatcttcaaa
    13621 aagggtgcgc gcatgaaaat caaaaagatc tttaatcaaa atgcagtatt ggtagatgac
    13681 ggtggacagg aaaaagtagc tattggaaaa gggattggat ttgacagaaa aagaaatgat
    13741 ttgatttttg atcgtgatgt cgaacggata tttgtcatgg aaccagaagg tcaaatcaag
    13801 ttgcaaaatt tacttaatca gattgatgaa cgctttttat ttgcagcaga aacgatcatt
    13861 gatcatgcgg aaactgtttt gatggaaaag ttgaatgaac atgtattgat cgctttgacc
    13921 gaccacattg ctttttctgc ggagaacatt aataacggta tcgtcatccg caacaaactt
    13981 ttaagagaaa tcgaagtgct ttacagtgat gaattcagta ttgctcaatg ggcagtagag
    14041 tatctgacaa aagagcttgg gattccatat acttatgacg aagcaggata tatcgcaatc
    14101 catattcaca gcggacgaag cggtcggaac aataaccatc gcagtatccg tgaagtgacg
    14161 attgtatctg acatcatcca tttagtggaa tcagaattgg aaacagatat ccattcagaa
    14221 ccattttcac tgaattattc aagactggtg aatcatttac gactgcttct acaacgaacc
    14281 catgcgcaac aatatgctgt tttagacacg gaaatcgtag aaatggtcaa acgaaaatac
    14341 ccagaaagct ataagatttc taaaaaaatc cgtgtgttgc tgaccaaaga ataccagctc
    14401 gcgatcacga aagaagaact gggttacttg gccatccata tcgagcgttt aagaagcgca
    14461 atcgtacaaa caaatgttaa caatcatgag gaggaaaaaa attgaaagca tatctacaac
    14521 gaatgggacg ttcccttcaa cttccagttg cggtcttacc tgctgctgct ttactagtag
    14581 ggatcggaaa ctggtgggca tcttatagta acgacattgt cgctcatttt ttacaagctg
    14641 gcggtaacgc agttttaggt caattacctt tgctgtttgc cgttgggtta gcactaggga
    14701 tgtcagtgga caaatcaggt gctgctgcct tggcaggttt ggtcgcattt gaagttccag
    14761 taaatgtttt aaaaactgat tcagtagcta ctttattgaa tatcaaacca gaatcagttg
    14821 atccatcttt tgctcagatc agtaacgtat ttattggtat tatttccgga ttgattgcgg
    14881 cagctcttta taatcgtttc cacgaagcaa aattaccgat ggctttatct ttctttagcg
    14941 gcaagcgtct agtgccaatc ttggctgcct ttgtcatgtt gctgatcagt gcagtgctac
    15001 tgctcgtatg gcctccggtt tactctgctt tagtttcttt tgctaaattc attttgagtt
    15061 taggctgggg tggtgcaggt ctttatggct tcttcaaccg tttactgatc cctacaggat
    15121 tgcatcaagc aatgaactcc gtgttctggt ttgacgtagc aggaatcaat gatattggta
    15181 aatttttggc ttctgaagga acaaaaggcg taacaggaat gtatcaagct ggatttttcc
    15241 caatcatgat gttcgggctt ccagcaggag catatgctat ttacagaaat gcacgtccag
    15301 aaaacaaagc aaaaacagct tccttgatgc tagcagcagc ttttgcttca ttctttactg
    15361 gtgtgacaga accacttgaa ttttcattta tgttcgttgc ttggccatta tatgtcttgc
    15421 atgcaatttt cactgggatt tctttagcag tgagtgcatt cttccattgg acagcaggat
    15481 ttgcctttag tgccggattt gtcgattact tcctatcttt gaaaaatccg attgcgaatc
    15541 agccattgat gttgatcgtc caaggattag taacagcagt gatttactac tttggcttta
    15601 actttgctat caaaaaattc catctgatga ctcctggccg cgaggaagca gatctttcag
    15661 atgacgatac tgcaacgact aattcagaca ataaatatgc ggcacaagca agcaaaatct
    15721 acgctgcatt aggcggagcc gacaatgtaa cttcgatcga taactgtact acacgccttc
    15781 gtttgcaagt caaagataca ggcctgatcg atcaaaataa aatcaaagcc actggcgtac
    15841 ctggtatgaa gatcatcgac ggaaaaaatg cgcaagtcat cgtaggtaca gaagtacaat
    15901 tcgttgcaga tgagatggca aaactacatg gtggtgctgc agcacgacct gcacaaacaa
    15961 acaccgtggt taaaacagaa acatttgccg gtgaaacgat cgaacaagat atttacgcta
    16021 tcgcaaatgg gaaactgatt ccaatcactg aagtttcaga tgatgtattc gcggaaaaaa
    16081 tgatgggtga cggctatgct gtattaccag aaaatggaga aatcttctct ccaatcgctg
    16141 gtacgatcac aaacattttc ccaacgaaac atgctgtcgg aatccaaaca gatgctggta
    16201 tcgaagtctt gcttcatatg ggcatcaaca ctgttgactt aaaaggcgaa ccattcactt
    16261 tatatgtaga agaaggtcaa aaagtcgcaa gaggtcaatt gattgcttta gttgatcttg
    16321 ccgctattca atctgcaggc aaaaacacgg atatggtcgt tgtattcaca aatggcgaca
    16381 aagtccaaag cttagaaatc gaacccgcac gtgatgtaaa agcaaatgat aaaatcggct
    16441 ctgtttccaa caaagcctga gccatcgtct tccccagact tttttatcga taaacaaaca
    16501 ggagctgaga caaaaatctt gtctcagctc ctttttccga ataaaaacgg cgttctcctg
    16561 ccaactccgc ggtaataagt ccagctaaac gaaacatatg aagagctatt ttttatttga
    16621 ctcttcttat tacttgatgc agaacagctt tttcacaaaa tttttcttca tactcaaaac
    16681 taatcggctt tttcacaacc tctttataca ttattcctga tccaatattt cttttaatgc
    16741 tgcttcaaga gaagttaatg gttttcccaa tactttttct aaatcatcag aggaaatagc
    16801 taactgatcc tttttaatat catgttggat cgctaaaaac atgtcagctg cttcttgagg
    16861 gaatccggct tcttttagat tttcgacaaa cgctgcatca cttgcttcaa taatttctaa
    16921 ctctttacct gtcgcacgct ctaatgcctt ggctaattct tcatagtcag ttagattgcc
    16981 ggataattct aagatttctg gagagtcact ttctactagt acttttgctg cagcttctgc
    17041 atattcacgt ttcaatgccc aacctgtttt tccatttcct gcagcataaa cgaattgacc
    17101 agtttttaaa gcctgcccaa tgataggtaa ttcattctct acataccaat tattccgtaa
    17161 aaatgtatgg gaaatacctg aatccttaat cattttttca gtgaattggt gatctggcgc
    17221 taatacactg atcgagtgat cggcatctgc aaaacttgta taagcgatat aagatacccc
    17281 agctgcttgt gctgccttca ctacattctt atgttcggct tgacgatttc ctggaacgcc
    17341 agagacaaaa agcaatcgat ctattccttt caacgcttct ttcattgagt ctaaatcatc
    17401 ataatcacca atacgtatat taaatccagc ttctttcagt gcttctcctt tttcttcact
    17461 acgtactagt acatagattt cattttgtgg aaccatcttt tttaagaatt ccagcgcata
    17521 accaccaaaa cctccagttg ctcctgttac taaataatgc atatttgcca ctccctattc
    17581 tttttatttg ttaagattta cagctgtaca tttataaatt acacctttat cataaagagt
    17641 gtggtaagat aagtcaagca aaaaaaatga aaggatgaca actgatgaag tattctctgc
    17701 aatttagtga tgcaatccat gtacttgcct atattgaaat gtttcaagat acccgatcac
    17761 tttctagtga gatgattgcc agtagtatcg aaacaaatgc agcaaatgta cgtaaaatca
    17821 tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac cggaaaaccg cagccttccc
    17881 ttgccaaaag tccagatcag atttctttac tagatgtcta tcgcagcatc gaaggtaata
    17941 cacagcttat ccaagtcgat ccaaaaacaa atccaaattg cgtcgttggt gcgaatatcc
    18001 aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa ggcagaagaa gaaatggcta
    18061 agatcacact tgatagtctg atacataaaa tagccgtttt ggaaaaagaa aaaagaccag
    18121 aaaacacagg cctcgtagag agatttttat aattctctct actgtgcctg catttttctg
    18181 atcggaatcg tctacataaa ttcttttatt ctccggggga caaaagcctt gtcatgcccc
    18241 tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat gacgtcttga taaacggtgt
    18301 tcaagtagct gaccctcggc attagttctg aaaaatgcaa aatatggaaa gctatttccc
    18361 atttttcctc tctaatgctc aggtcaaagc gctactttca cgacctctat attatcatgg
    18421 tttattgact accggtatcc agatttctcc catatatttc ccgttggtaa ctcccatttc
    18481 gactacagca tttggacccc caacataggc gtaatcttct acttctctta aaacatgccc
    18541 aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc gattctgcta aagcgcttac
    18601 aacaagatac gttccttttg ggaatgggat gattcgcgta gtgtttggaa catcctgact
    18661 cgtttgaaca ccgacatagt acatcatttt cccgttatag ggttcgttga ctgtaaagaa
    18721 ataatgattt tcagcagctt gtttcaatgc atctattgtt ccattaccga taactttttg
    18781 ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc gtattgctac tcttcaattc
    18841 cacaccaata cccgtcaccg taaaatctgg tttttcttcg atcctatact ttgccatttc
    18901 tcccaccctt tctattatat taagttcatc ttacataaaa ttaaagggaa atgacacgat
    18961 tacgctcttt tttctaggga tatttttatt ttttaactat ttttttgctt tcactgcaat
    19021 ccaaatctca ctgtaaacat tactgaaatc ctctccccat tttgtaaaag agatctcggg
    19081 agcttcgact aacccataat ctgaagaagg aagccattct gcatagattt tcccccaagt
    19141 atcttgtaaa gtttggggaa atggcccttt attaggaaaa atggcccaag tgtgttcttc
    19201 tatagcaagc atttctaaat cagcgtacgg attttctttt gtcgtagcaa agccaatcat
    19261 gtgcatcaaa ctgccctttt cttccaagcg gtctccatca aatccataag aaacgttgat
    19321 tacttgattt ggatataaat ctcctaactt atgcatctct tccctttgag tctccgtgat
    19381 cgtctgcgct aacttttgta tttcttgatt gactccttca aatttgacag gaactttttt
    19441 cgccacacct gccacataaa actgttcttt cttttcgata cgaaattcca tcgattttcc
    19501 tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat ttttgtatgc cgtatctgct
    19561 gatttctgaa ggcagatatc ctgaccaatc acgaaaagct cttgaaaaac cttcgactgt
    19621 ttcatatcca tatctaaacg ccgtttctgt cactcttgat ccatctagaa gatcgcgatt
    19681 agccaaagcc aatctacggt ttttgatata gtccattagc gacatccctg caataaacgt
    19741 aaagatgcgt tttaattgat attcagagat tcctgtattt tcggctatta ttttatagga
    19801 aagtccttct gtcaaatgtt cttcgatgta atcgatcaat tggttcagat ctttaagcat
    19861 atttatcttc ctccttgatt gcctttttat catattatca aagaaagtca attacttgat
    19921 gaatcaggaa ccaatttagt cagatgtaga aaatgttgta tggatctaaa gaaaattctc
    19981 aagcagcgtt tcgtaacgga taattggtat tatctgccta tctatgtttt acctttagaa
    20041 aaataaattt tggggaagac agattctaag taaacaaagc ggtaaaaata tcttttattc
    20101 ccttagttaa tccgcttact acctactgta caaagcaaat tgttgttcaa actgctgatc
    20161 agaacgctgc ttggattttt ctttgcagtc aagtccacaa tcttgtgtaa aagttcaacc
    20221 tcatcaaaag cacaatgttt tgcgttgtga acctaactgc catgcctttc tttctgagga
    20281 gagaggtcag gagcagtagc gcagcgactc ttgatgtctc tcctcagaaa gaagagactc
    20341 gcacaggttc atggtgctaa atgttattcg aattaaattc taaatatttt cgtggagaag
    20401 ccagccactc agtgtctttt tccatcaaaa gtgttccaat tatccgagtg atggaattga
    20461 tatttggaaa aatccgaatc actcgttctc tccggcgaat ctcttcgttc aaccgttcca
    20521 acacattggt tgtacgaatc cttcggcgga tattttcagg aaaagacaaa atttgaatag
    20581 catcttcaaa gccgttttct aaaatgtcgc aagcagcact taattttgaa tcacaaccat
    20641 atttttccaa gaagtgctct tttctttcac gtgtcaattc aagttcagag gctttaaaga
    20701 tactcttcaa ctcgtctttt acatcagaag aaactttctt tggcagctta tcaaaaatat
    20761 ttctcaaaaa gtgggcttgg catctttgcc agctcgcacc taaaaagttc ttgcgaacag
    20821 ccttaactaa ccctttgtgt gcatcagaaa tgaccagttt tacaccgaac aaacctcgtt
    20881 gaacgaacga ttgaaaaacg gtatcccaat tatcttccga ttcgccgtct tgaacatcaa
    20941 aaccaagaat cgtacgtcgt ccatcagaat caatgccgat accaatatat acaccttttg
    21001 agacaatacg atgattttcc cttactttca tatacagggc atcacacatg aaaaatggat
    21061 attccgagcc ttctaggctc cggtttctcc actcaaaaac aaatggatcc aactgtttca
    21121 tcagatttga aacgaatgat ttagaaacag tcgcaccatc cgttagcagt tcaactgttt
    21181 tagttacttt gcgagtggag acaccagaaa tgaccatttc aatcatggca gcgatcaaag
    21241 ctttttcgct tcgctgatat ctttcaaaga tagtaggact aaacttaccg tctctggttc
    21301 gtggaacatg aagttctaac gtaccaattc gagttgtaaa cgaacgatcg tagtaaccat
    21361 ttctttgtga ttgccgttct tctgaacgtt cataggcatt tgcctgaata tattgatttc
    21421 gttgttcttc catcagctga ttaaacatga tagtcataag tgtttttgcg gtatcattcg
    21481 caccgctttc gtttataatt gcttgaattt cttcgctttc aaaagtaaaa tgtacttgag
    21541 tcattgatat cagtcctatt cgagtatgtt ttctgcaaaa aacattgtac tcctaactga
    21601 gatcaatggc ttttttgatg cttcactttt acacaattat atggacgtaa tcttctttgc
    21661 gatacatcat acctctttta tcaattggaa caattattta tttctaacaa aatcacttca
    21721 tttttgtcag ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta
    21781 ctttttctca cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa
    21841 agtgattatc aaatatgtaa aatcagctac ttttttctta aacgtttctt tatactaaat
    21901 ataaataagt gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga
    21961 aaacgttttg gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta
    22021 tacaagcaag tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac
    22081 ttgggatgaa aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg
    22141 caaacacatg gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta
    22201 ctcactttcc gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct
    22261 tttaacagag attcttatag aacatccgca ctttatcgaa cgcttcaaag ttaagatgcc
    22321 atttcatgca ataaattatt cagataaatt aacaactatc atccataaat acgatcatat
    22381 tatcaagaaa aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat
    22441 ccaagaagca gttgaatcgc ttattcagca aaatgcctat cttcccgcat tcgaattgat
    22501 caatgaagtg attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct
    22561 tcttctgata gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc
    22621 agaaaaaagg caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta
    22681 ttcaaaacgc tactctataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa
    22741 ccaaaagaaa aaaatagata aaaaactaaa gaaacggtaa agaaagacga tttcaatgaa
    22801 aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc agaccttgct
    22861 ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta cccaatatta
    22921 gtcatttgac tattaggtac gcgttttgtt ttataagtca tgacaaattt ccttcgttgc
    22981 tggatagatt ttccggcatt gttgatagat tttatgatac ttttctacat tttgtaagag
    23041 aggttccact gcatctgtat attggataaa attctgacaa caactttcag gtgtgtcgaa
    23101 ccaccctaac cctagtgcag caatcattgt tgcgcctaat gcaggtcctt cctccacact
    23161 taaacaatag accgttgcat cgaaaatatc agcttggatt tgtagccatg caagattttt
    23221 cgcgcctcct cccaccgaaa caatacgtgt aaatctgcga cccgctagtt ctttacgttt
    23281 caatcccacc attgacaaat gctcattaaa aatttagaat attcacaagt ttaacgacaa
    23341 ttatgaaaat ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt tagatataaa
    23401 aactgcgatc aaagacacgt tacctaccgt tttcggttat atcggtattg gacttgcatt
    23461 tggtatcgtt gggaaagctg ccggatttca tccactagtc gtcacgttga tgtccctgct
    23521 ggtctatgct ggttctgccc aatttatcac agtcagcatg cttgctagtc acagcccatt
    23581 gctttccatc gttttctcga cctttctagt caattcccga atgattctga tgagtatgac
    23641 gattgctcct tatttcaaga aaaatcggct gcttcaaaat ctgctgattg gcacattgct
    23701 gacagatgaa agtttcgcac tgggaatgaa taaattgaac tatactggac aaaagttaaa
    23761 ctttcgttgg atgaatacag ctaattggat ttcttatttg acgtgggtgg gttcttctct
    23821 tgttggcgca cttttaggga attttattac tgatccgaaa aagtttggtt tggatttcgc
    23881 catcgtcgct atgtttatcg ggttacttta tcttcaagtc atttctgata gaaacacctc
    23941 taaacgatta cagttgatcc tgattggtct cactttgatt ctggtatatg tcggactgat
    24001 ttttatccca agcaacttag tgattgtagt tgtaacactg attgggtgcg gattgggggt
    24061 gtggatcaaa catgccttct tttgagttta cattgctgac tattttaggt tgtactttag
    24121 caacttggct ttctagggtc ctaccatttg tcttactgaa aaaattcgat ttaccgcaac
    24181 cgttgcttga gtatttaagt tttgtcccga tcgtcattat gtctgcttta tggttcagca
    24241 gtctatttac ccaaaatatc ggacatctgc cgcagatcaa tctcgaaaat gctttggctt
    24301 cagttcctac acttttagct gctattcttt caaaaagctt attggtgatc gtcttggcag
    24361 gaattctttc cctttcgttg attcgcttat tataaataaa aaaacaagag cttatggcaa
    24421 attactgtca tgcgctcttg tttttatcaa agtcaaataa gaaaaaaatc ggcgtattct
    24481 tgcttatccg ttgaacggac cactaacaac gacttttcct aacatatgtc ctgtttctac
    24541 gtctttggtt gcttgtttca agttcttcgc attcatccca tctgaataga ccttgctcaa
    24601 tgtactgcgg ataatccctt catttgctaa agcagcaatg tgcgctaaag cttctccttg
    24661 cgtttcgatt tcatagttat agtctgtttt agcgaacata tactcccagt cgaagctgat
    24721 agattggttt ttccaaacac ctatatctaa cggctctttg atccctacga tcgttcccac
    24781 atgtccaaat ggtcggacaa ggtgcttgat ttgatcaaag tagcgggtaa tatcgaataa
    24841 tacagcgaca tactctactt gatcgattcc taattcacga aaacttttac ttaagtcgtg
    24901 atgataatcg attggatagt ctacacctgt ttttttcagc cattcaaaat tcttcggact
    24961 tgcagtcgcg tagacttcta ggccagccca atgcgctagt tgattcaaaa tcgaaccgac
    25021 gcccccggat ccgttgatca ctaagatttt tttcccgcga ttggcatttt cttctggagt
    25081 tagaccaaat ttttcaaata acaattcata agcggtcaat gaggtcaacg gcaaggctgc
    25141 agcttcttca tctgaaagat tttttggtgc aagagcgaca atacgttcgt caactagttg
    25201 gtattcttga ttgcttcctg ctcttgttgt tgtacctgcg taaaaaacgc gatcgccgac
    25261 agaaaatttt tgcacttcgt cacctacagc aacaactttc ccgactccat caaaacctaa
    25321 gatacgtaaa gcatttctta tcccgttatc ttggcgaagt ttcgtatcga caggattaac
    25381 agatactgcg ttgactttta ccagaagatc ccgtgaactg ggtacaggta tctgttcttt
    25441 ttcatcaata aagctttttg gatcatcgat cggcaaccct tcataaaaac cgactacctt
    25501 cattaattcc ttttctgaca tacgaattcc tccttagctt catcaagttg gagcatccat
    25561 acagtgttca tttcaatata tatagtatgc tatttgttcc acctttttta ttcatcataa
    25621 ttattctctt acttaaagta aactatttgc acttttttgg ttaaaaaaga ggttgcgaca
    25681 agacttttgt cacaacctct tataaacggt gttctcctac caactcttcg gtcacaagtc
    25741 aaaatattca tcaaacatga gaagctgttt tttgaaattg ctccttgtga ctcagagtta
    25801 aacggcaggc tcacaacctc tgatataaac ggtgttcaat caactgaccc tcggtattag
    25861 ctcaaaaaac gacaaaatat gaagagctat ttttgtttgg ctgttcttat tacttgatac
    25921 aggacagctt tttcacgacc tctaattcac ggtgttcaag caagaaatca ttgttcactg
    25981 aaaagcgttg gatgttcttt ttcaaaggtc tctaagatct ctcgtacttc atcagtagat
    26041 ttcgtattca tcaactgaac tcgcaagtca tttgctcctg gaaatccttt gatatagatt
    26101 ttaaagaaac gatgtagtcc tgtgatggaa cgcgggatga tttctgaata atgatcttgc
    26161 agatctagtt gcagacgaag tagtccgatc agttcttttt ctgtatgttc cctcgggtct
    26221 ttttcaaatg cataaggatt cttgaaaatc cctcggccaa tcatgatgcc atcaacgcca
    26281 tatttctcgg ccaattcttc tcctgtctgg cgatcgggga tatctccatt gatcgtgatt
    26341 agtgtttgtg gagcgatttg gtcacgtaaa gcaatgattt taggaatgac ttcccaatgt
    26401 gcatctactt tactcatctc tttacgcgta cgcaaatgga cagaaagatt ggctatatct
    26461 tgatgaagta ggtgactgat ccattcttcc atctcagaca tttccgtata gccgatacgc
    26521 gtcttgacgc tgacaggcaa accgccagct ttagctgctt caatcaattg tgccgctact
    26581 tctggacgaa ggatcaagcc actgcctttt ccacgttctg ctacattagg gactgggcag
    26641 cccatgttga tatcgattcc ttggaagccc atttctgcca tagcaatgct catttctcta
    26701 aaaaattctg gcttgtctcc ccaaatatgg gcaaccatcg gctgttcatc ttctgtaaat
    26761 gttaatcttc ctcgtacact gtcttttcca tctggatgac agaaactgtc tgagtttgta
    26821 aactcagtaa agaagacatc cggtgctgct gcatgcttta cgacatggcg aaatacaaca
    26881 tctgttacat cttccattgg tgctaaaaca aaaaaaggct ttggcagctc tttccaaaaa
    26941 ttagtagtca tttatttgtt actctccatt ctatcaagca gtgaagtcgc aatctttctc
    27001 aaaaacattg tcattatact aggaaacaaa aaaagaagca aagtgaacag cttaaaagat
    27061 gtttctgatt gagcaaaaaa aagactgtga caaaaatctt atcacagtcc attttccgga
    27121 ataaatggtg ttcaaaagct tgcatctgcg gtaataagtc caaccaaacg aaaaatagga
    27181 ggagctattt ttgtttggct gttcttatta cttgatgcag aacagctttt tcacaacctc
    27241 tccactaaac ggtgttcaat cagctgaccc tcggtattcg ctcaaaaaac aacaaaatat
    27301 gaggaactat tttcccgttt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
    27361 tcttttctaa cttctcaatc ctcttccttt attgatcaaa taccaagtaa cggcgtacaa
    27421 aacaacgatg aataacacaa gtacgatcat cgatgttgct actggcacat cgatcgttcc
    27481 aaggaatccg taacggaaac cggagatcat ataaacgatc ggattgactt ttgaaacagc
    27541 ttgccaaaag ggcggtaaca tagagatggc atagaaaacg ccacctagat aagttaacgg
    27601 ctgcaagaca aatgtaggca cgatcgatac atcatcataa gactgagcaa aaatcccgtt
    27661 gagcagtcct gctaatgaaa acaagattgc cgtcatcaat aatgtaatga tgaccatgaa
    27721 ccatgaatac acatgaagtg gtacaaagaa caaggaaatg atcgttacga gagagccgac
    27781 gagaatactg cgacccacac caccaatcac aaagccccaa ataatcacat gcgtaggaac
    27841 aggtgctacc aagatttctt cgatattttt ctgaaatttt tgagagaaga aggacgaaga
    27901 aacattggca tacgaactag tgatagcaga catcataatc aaaccaggaa cgatgaattc
    27961 catatatgaa aaaccaccca tgtcaccgat ccgcccaccg atcatttttc cgaaaataac
    28021 aaaatacaag gatgtcgtga tcactggcgg aaccagtgtt tggacccata tacgcaaata
    28081 gcggttcgtt tccttgatag ctaaactttt taatgcagta aaataaagat taaacatttt
    28141 tctcctccgt atgattattt tcttctgtga ttttcaagaa cagttcttct aaacgattcg
    28201 acttattcct catagaaaga actttgattc cttgtcttgt aagctgatcg aagattccgt
    28261 tcaccccttg atttcgttca acttcgacag cgattgtctg ctcatcttca aatgtacaag
    28321 catatccttc aatcacaggt ttggtatcat atggcgctaa atcaaagata aatgtttcaa
    28381 attgcagttt tgacagaagc tctttcatac ttgtattctc gatcagttca cccgattgga
    28441 tgattccgat gttgcgacaa agcatttcag cttcttctag ataatgcgtc gtcaaaatga
    28501 tcgttgtacc attttcgttc aattctcgta gaaactccca catctcgcgt ctcaactcga
    28561 tgtcaactcc tgctgttggt tcatccaaga tcagcaaacg tggttcatgc atcaatgccc
    28621 tagcaatcat cagtcttcgc ttcattcccc cggaaagcat acgtgcacgg acatttctct
    28681 tttcccaaag attggactgc ttcaaatatt tttcgctgcg tttcatcgct tctttgcgag
    28741 agacaccgta gtagcctgct tgattcacga cgatttgctg gaccgtttca aaagggttaa
    28801 aattgaactc ttgtggaacc aatccaatct gttgctttgc tcgaactaga tccttgtcca
    28861 gatcataacc gaagacattc acttttccag atgttttatt gactaaagaa gtaataatcc
    28921 cgatcgttgt agacttccca gctccatttg gccctaatag cgcatagaaa tctccttctt
    28981 tcaccgaaag atcgattccc cgcaatgctt cgaccccact tccatagatc tttttcaaat
    29041 tatttatttc aagcgcattt gccatttatt tcctatctcc ttatagacat gattcttaat
    29101 tgtatcatgg aatacagcag atgaaaaaac aacttggctt ccacacaaaa acacacctgc
    29161 taacaaagag gagatgtgtt ttctagttca tgatcatctt cgatagaata actatctaaa
    29221 caactctgga acttttaaaa tcataaaagt accgacagca actactacga tgacatatag
    29281 aagatcctta taactgaggt tcttgtcttt tttattcatg ttaagctttc ctccgtcctt
    29341 ttatcgaaag cttttttctt ttattttaac cgaaataaat aaaatggaaa tagttatttt
    29401 caatttctgt tttcgctgtt tgttttacgg agaactttgc catggaacgt gcgtctcgtc
    29461 gctgatgcta agttttttcg ataaaagctg ctagaaggaa gacagcgtgg tttattttgt
    29521 atcgtctttt gctaaatctt ccaagatcat ctggacagca gactcgttcc cattgaattc
    29581 tgccactttt ttggcatcaa tgtacttctt ttgataatcg tctttttgga cccacgcatc
    29641 atgcttcgtt tgataaagtt aatcaaacgg ataccactga cgctgttcat cgaacaacaa
    29701 actttctttt tgggcctgtt caactatgga tttaggataa ttcaaaactt tcagcaaggc
    29761 aatcgcattt cgggtccttg aaggtccttc ttttaatttg aaatcaaaac tgattccttt
    29821 tccttctgtt acttgttctt caaagtggac attctcacaa taattcttta aaatctctgt
    29881 caattcgata tcatgtgtgg cgacaaatgc taaagatgga tactccgcaa gccaccgaac
    29941 gactgaagcg gaagaagcaa tccgttcgat cgtatttgtt ccttttaaaa tctcatctac
    30001 gaagcagtag cagcgttctt tggaagccac ttggtccagc aaacgtttga tcgatttgat
    30061 ttctgaaaca aaataactgt cgccttcaaa taaatcatct tcgattgcca tggaagtcaa
    30121 cacatgtcca ggttgcaggg taaactgttc tgcaatcgct gtttggatcg tctgtgctag
    30181 aatacagctg atggctatac ttttgacata cgtagatttt cctgatgcat tggaacccgt
    30241 gactaatgta ttcttctgcc agttgactgg attaactacc gcttctttta acaatggatg
    30301 atagatatct ttcgctgtca caccgccctc agtaaactct ggtcggcaag tgatcggcat
    30361 ataggtgcga taattcaaaa cggctgctgc aacttccaat tctcccagca attcccacag
    30421 cttgatggct tcagttgaat gcttttctaa tttagtgaga acgaaatgat aggagataaa
    30481 tggcagcatg aacatgatgt tgacatattc aaaaatcaat tctgcttcac tcccgctctt
    30541 cattcgaaat gaaaaaccta atttagggat gtctcttaat ggtttagttt gctgtttcag
    30601 ctctttttga agtggtgtcg tcatttttgc taactgattg gcggctgaaa tcgttgaaac
    30661 caaataactc atgctattca gctctgtttc tagtgtttgt ttcttcacta gataatagac
    30721 cgtattgaat actaagccac cgattgctag atagattcct agtacttgcc ctaaaagaag
    30781 caaacctaca cccaccagcg gaagcaagcc aagaaaaata aataaaccta cgcgtccaat
    30841 ctttttactt tttccatccg ctagatattg ttttgcaaaa ttatgatctt tttttcctaa
    30901 acgagcgaat tgatattgga ttctttctct cagttgagga ttttcctgat aaaaagcaat
    30961 tagtttttct aactgataat cttctccaaa atcaaagcta cgtaaacgct gatacaacgc
    31021 ttctgaacct acactagaat aggtactgtt gatcccttca aatacttcga acatatccaa
    31081 gtcataccaa gtaagatcgt cgatttcact atcccatgaa cggaattttt tctccgtgag
    31141 ccacgcatcc ttcaaacttt cttctttatc aaatctcggt tgataaggaa tttttcccca
    31201 attactacga actgtttcct ttactttcaa acgtgaaaaa atgtctaaaa caactaataa
    31261 aataacaact gcaataataa ttaaaacgat aaattctctt tggcccatat ccctctccgt
    31321 tccttgattt gttagtttta gtatagcact gttgcgctat ttgaaaaggg ggtacaaaaa
    31381 taactgtctt cgttacctaa ttcgtatcaa tcacaccaaa ataaaaacac cttccaaaaa
    31441 agaagatgtc tttaaaacga gatacaattt tttgtcattc acttcaggta aattagagcc
    31501 aattaaaccc tccgcaactt gacggagatg gagaagatgc ccccgtctaa tctagcggtc
    31561 atctctcctc ccattccttc caccaatttt tttgacaggt aaagcccgat tccgctagat
    31621 tccgtatttg tgcggctggt attttcggta taaaaacgct ggaagacttt ttcaacagag
    31681 gtttgcgctc ctggtttgat aggattggcc actgttaatc gaatgaatga atcctctttt
    31741 gaaaatgtca cctttgcttg tccatctgca taacgcaata aattctgtat gatattttgc
    31801 agcactcgca gcaacatgag cggatctgct aatacagttg tatttatcga gtgttcagcg
    31861 aacgctacct cgatattttt ctcagaaaat tgttcataaa aagagaaaaa tacttcttcc
    31921 acctctttag aaaaagaaag cgtatggaga tccatttctt tttgcttcgt ctctattcga
    31981 gcaagatcat aaaactgatc cgtcatactg agtaatcttg caacagattg tttgatgatc
    32041 gttaaatact tctcccgttt ctccgtatcc tctacctgtt ccagtaattg tacataaccg
    32101 ttaatagcag tcaaaggagt tctgagatca tgagaaaggc cgacgatcga tagtctgatg
    32161 ttttcttcca tttcttgaaa tgcttgtcct ttttgttcat tttcatccac ccatgtattc
    32221 agtgcatcta ctaggtccat tagattcttt tctcgaaatt cgactgaaag acgaccacca
    32281 tattcttgtc gttcagaaag agtggcgatt ttcttagtta atctcttgat ttccctttgc
    32341 aggaagaaaa taaaacttcc cataaagata acaacgagaa gcaacagcca cttaatcaaa
    32401 tctaaacccc actccccaca ccgtatgaat atacacagca tgtgcctttg ctagtttccc
    32461 tcgaagattg gaaatatgca tattcactgt tttctcacta tcaaaatatg gttcttgcca
    32521 aactgtttca taaagatttg ctcgcgaaaa tacttttttc ggatgttcta aaaaaagctt
    32581 cagcagatcg aattctcttc ctgtcaaatg gacagccaca ccattcacat ttacatccct
    32641 cgactctttg tccagtaaga tttccttgta atagatgcgt tgcgacagat cttttacttg
    32701 gacagaagtc tgatgacgaa gttggatgcc gattcgtaac aacagttctt cgatatcaaa
    32761 tggtttcgtc acatagtcat ccgctcctgc tgccaacaag gaaactttat ctctttgatc
    32821 gctttttgct gaaagaacga tgatcggaac attcgatgtc tgtcggattt ctgctaacaa
    32881 tgcttcacct gaaagccctg gaagcatgag atctagaagg atcaaatcga caggatatgt
    32941 gcttaacaat aattttcctt ccgtacctga ataagcatca agaagtttgt atctctgttc
    33001 aagaacctcc tccagtaaag aatgaacagc ttcatcgtct tcgataatca aaatagtttc
    33061 cagcaggaac acctacttaa tgtcagattt ttggaaaata aacattccta gagctgatga
    33121 taccacgatt gttactagac tgaccagaat cattttcggt gcttgcgaat aagttgcttg
    33181 ttgcgcaaag tccgtataca tgagccacgt ttccgtaaac cactccgtta gaaattccaa
    33241 gcctttgatt tttgcgaaaa caccgggaac gaaggccgtt cccatgatat aaagaaaaga
    33301 aagaagcaaa ctgacactgg tacttctagt gatgaatgtc aaagccactg gaacagataa
    33361 tgtcgctaat atcagcagaa gcaatacagg aaatactttt agaacataat ttccatagtt
    33421 tttgattccc tcaacttcac caaatccgaa agcaagtgtg taagcaatca tggctagccc
    33481 cgtaatcaaa accacgccaa gtgttgtgat caaaagcgta acgagaagtt tcgacacata
    33541 ataagtcatt cgattccgtc ctaaagataa cgtattgcga atcgtaccgt tttgaaattc
    33601 ttccccaata taaaagcacg caaatgctgc gaaagccaga agaatccatg cagccatttt
    33661 ttccaccatt aaaatccctg ttgcaccgtt gatgactgta tccgttgctt ggtttaattc
    33721 attgccgtat tttgtatgca tataccattc gttccaagaa taaaaaagcg gaagtacgac
    33781 catcagtcct agtgagaccc acattttacg gctcttccat acttttattt tttcagcagt
    33841 taatagatta aacatgtgga ttgcctccag ttaattgtaa gaaataatct tccagttttt
    33901 gcccaactag gtggatacca tccacaggaa cttttgcctc taccaatgct tgattgatgg
    33961 ctgctacttg gtcaattcct tcaaaaagct ggataacacg gctagattgg acaaaataat
    34021 ccctataacc aagagagtcg agaaccgtta ctgcttgttc cgtcgccgaa gtgtcaattt
    34081 ttataaattg acgagattct tgtgccaatt cttctttcga taattctttg atcaagtgtc
    34141 cttcatgcaa aataccgtag tgagtggcga tctgtgacaa ttcatctagc aagtggctag
    34201 aaagcaagac ggtgatgccc cgttctttta ccaaacgttg gatgatttct cgcatttctg
    34261 ccatccctgc tggatccatc ccattcgtcg gttcatccaa aatcaaaaat tctggattcg
    34321 tgatcagtgc atttgcaata gctaaacgct ggcgcatacc taaagagaaa ttctttgctt
    34381 tctttttccc tgtattttcc aatcgcatca ttttcagcag gtcttcgatt tctctatccg
    34441 acacaccgcc gttcgctgct tggatacgta ggttatctct tgcagttaat tctggataaa
    34501 gagcaggggt ttcaatcgat tgacccatac gtcgtcttgc tgcctgcaaa tccgtcgttc
    34561 caaataattc gatcgaacct tcatcaatcg agatcaaacc cataatagtt ctcataaagg
    34621 tagacttacc cgctccattc tccccaatca aaccatagat cattccacgt ttgatttcga
    34681 tcgatacttt atctaatgct ttggcagcac cgtatttttt ggttatacca gttgctttca
    34741 agaccgtttc atttccaaaa tccatactta tccttctttc ttattgataa gtgaagtata
    34801 gttgacgggt ataaagaaag cagccagaaa tgtataaaga aagtgtaaat tttccaattg
    34861 aatttcaaga aaaatcagac tgtctcgcag acgtggttga gttgtctgcc aatcaaagag
    34921 cgcaccaaac agtgctaatc caagtggact ggccaccatg gtaatcgttg ttatcgttga
    34981 catcagacgt ccttgtatat gcgttggaac ttctcgctga agccagacca tataaaaagc
    35041 aaaagaaaac attaatcctt aaaaacggac ttatgaaaaa taatacatgc cgtttgggat
    35101 ttacaattag ctaccaaata agaggttatg acaaaagact tttcacaatc ccttcttccg
    35161 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatattta tcaaacatga
    35221 gaagcaattt ttgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc
    35281 agaagcggat aaataatatt gtttgatgat actttatctt tttcccgttt gtttatagat
    35341 cgaatgatat tatagaccaa gaatcctacc tattaacata gctaaaaaca caaaaaaggc
    35401 actttccaaa ttgtggaaag tgccagaaaa gttaggatta aggtaactgc gctcagcatt
    35461 gcttcgccca gtacgattct cgtaactcgt gaactcgaac gataatcgca attaacgttt
    35521 tgagaactgt gaagctttac gggctttctt aagacctggt taaacaaaac tctattttat
    35581 tgcattttac aggaatgtat ttcatgcgaa attaataagt ctttgtttat agagttttac
    35641 tagggtataa aaagttgtat gttatcatta cctcaaaaca ttacctcagc ttggcgagtt
    35701 ggttgattga agaataaatc atttatctag atatctcaat aaaaaatgat ttctaagaaa
    35761 cttgtatttt cgtgttatta tttttttgcc ctatcaaaat ttctaattct tctagcgtaa
    35821 tatgattatg acacataatc gattcaatta cttcaatacc tatttttttc gagaaagatc
    35881 ccttttgttc actcacaaaa atactttcag aagacatata taaggaacga agttttggaa
    35941 ttagtatatc gtacaaatag accaccataa aatcgtcctt gcaaccattc tcaaaaagaa
    36001 ttaaatttgc tgattgtgtt acatatatca ctgaattaca ttcatggtca attccaaaaa
    36061 caatgtctac ttcattttct tttctaattc gcgcagttac atttttcaaa ctttcaccat
    36121 tacttataaa tgctttagtt actgtaagct ctgatgtttg ttcagatatt ccttttataa
    36181 tattttgttc atcagccaca ttccccataa atccgccgat tccttttaag taataattct
    36241 cacctaagag tcgcttgcat tcactgaatt gataaaaaaa ccagttaaaa aaatcttctg
    36301 gaaaaataaa ttctgatcga actttattta tatttttagc tcctattaat tttataactc
    36361 gattaatgtt cacttgctgc gatgaacata taactgaata aattgagttg tttaattcaa
    36421 aaaaacaact ttaacatatg catcattaat tcgttatttt ttaggtagat attgatcatt
    36481 gttatctctc tttttttgct tcccatactc caacttagaa attgccgtta taaaatttat
    36541 tttaaaggtg actttttccc ctgaagtatc ggtagtagga atacttaata cctcagcttc
    36601 tgaggaggta tcccaattat agttatactt tgcatcatca ccataaagaa caattccatt
    36661 ttttttatct tgtgccgtta gctttactgg ttcgcttact tttcttgtta atatcttgga
    36721 ctttacatca tcgatattgc ttattttatc aagcttaaat aatttacaaa ttaatttcgt
    36781 actagttttt atatttgacg agagtgtaaa atattttgtg taaatagaaa aaaggaagtc
    36841 ccttctgtag aatagagtta ccacaacaca ttcacagaaa agaggacttc catatgaacg
    36901 attttactac agaaattcta aagactctag cgaacaaagg cgatttgaat gaattattcc
    36961 gtgtccattt ggaaaaagct gtcaatacgc ttctcaaaac ggagttaacg gctttcctcg
    37021 attacgaaaa gtacgatcgc attggtttta acacggggaa ttctcgtaac ggctcctatg
    37081 accgtacggt caagaccgag tacggggaac ttcatctcca gattccgcgc gaccgcaacg
    37141 gcgagttcaa gcaacagact gttcctgctt atagacggac gaatgatatc ttagaggaga
    37201 ccgtcattca cctcttccga aaaggtatta ccatgtcgga aatcgcagac ttgattgaga
    37261 aaatgtatgg gcatcactac acgccccaaa ccatgtccaa catgactaaa gtgctgactg
    37321 aagaagtaaa tgcatttaaa gttagaactc taaatgataa gtatgtcgct attttcatgg
    37381 atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc tatattgcca
    37441 ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgct ccgactgaat
    37501 cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt catgatgtct
    37561 tactgtttat taccgatggc ttaaaaggca tgaaagatac gattcaccag atttatccta
    37621 aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat aaagtacgtg
    37681 tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct agctcaaagg
    37741 aagaggcaaa taccttttta gggagtatga ttgagaagta gcaaaaaact tatcctaaag
    37801 tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt ccgcctggta
    37861 tccgccgaag catttactca actaatttaa tcgaatcttt caagaaacaa atcaagaaat
    37921 acagccgcag aaaagagcag tttcaaaatg aagaatcact agagcgtttc ctagtatcca
    37981 tctttgatac atacaatcaa aaattcttaa atagaagcca taaaggcttc caacaagtga
    38041 cggatacatt agcttcaatg tttactgagt aacccattat tttgcagaag gacgagttat
    38101 ttacacaaaa ttattgacgc tccctccaaa ttacttcatc aaaacattga tataattttt
    38161 attatatcag tatttattct tgatacataa atgagaaaat aaatacttta aatctattga
    38221 ctacaagtag tcattaagtc ttcataagat gtacaatatg acattaaaaa aataaaagct
    38281 tacgaccatc cgttaaatct gacactaaat aatggactgc tttcttttgt attagcaggt
    38341 tacgttgact atgaatattc accagattat ttggagaaac ctcttcaaca cgagaacaat
    38401 gatattaatt ttagatttgt ctacgagtca aaaagtaaaa catggttagt tgatcaatta
    38461 agcacgataa acacaagctt ccatgaatta cctaaacctg aaaatgaagt tgagatggtc
    38521 attaaaatct tctaaaaaag aagcgttgaa ggggaaatat tcctttcaac gctctttttt
    38581 atatgcttag aaacataaat aaattgtata ctttcttttt agcccctatt acttttcacg
    38641 aaaaatatct ttttttcgac gctagcgttt ctctacttct aatactgtac acagtttttg
    38701 tattattgaa aaattactca ttatttagca ttaatccaca tcgttttatc aatcgacctt
    38761 catactaaac tactttaaag tcatcttcct tctcgttttt catt
//
LOCUS       DAZKPE010000021        36569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000021 DAZKPE010000000
VERSION     DAZKPE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.021"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="ACG930_001179"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="ACG930_001179"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFQ0518350.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="ACG930_001180"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="ACG930_001180"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFQ0518351.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="ACG930_001181"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="ACG930_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFQ0518352.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="ACG930_001182"
     CDS             complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="ACG930_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFQ0518353.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="ACG930_001183"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="ACG930_001183"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFQ0518354.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="ACG930_001184"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="ACG930_001184"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFQ0518355.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="ACG930_001185"
     CDS             complement(8054..8524)
                     /locus_tag="ACG930_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFQ0518356.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="ACG930_001186"
     CDS             complement(8570..8995)
                     /locus_tag="ACG930_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFQ0518357.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="ACG930_001187"
     CDS             complement(9062..9331)
                     /locus_tag="ACG930_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFQ0518358.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="ACG930_001188"
     CDS             complement(9342..10937)
                     /locus_tag="ACG930_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0518359.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="ACG930_001189"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="ACG930_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFQ0518360.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /gene="pth"
                     /locus_tag="ACG930_001190"
     CDS             complement(14490..15050)
                     /gene="pth"
                     /locus_tag="ACG930_001190"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFQ0518361.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="ACG930_001191"
     CDS             15403..16377
                     /locus_tag="ACG930_001191"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFQ0518362.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="ACG930_001192"
     CDS             16547..17947
                     /locus_tag="ACG930_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFQ0518363.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18025..18747)
                     /locus_tag="ACG930_001193"
     CDS             complement(18025..18747)
                     /locus_tag="ACG930_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0518364.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18826..19332)
                     /locus_tag="ACG930_001194"
     CDS             complement(18826..19332)
                     /locus_tag="ACG930_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0518365.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19455..21254
                     /locus_tag="ACG930_001195"
     CDS             19455..21254
                     /locus_tag="ACG930_001195"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFQ0518366.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21322..22896)
                     /locus_tag="ACG930_001196"
     CDS             complement(21322..22896)
                     /locus_tag="ACG930_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFQ0518367.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="ACG930_001197"
     CDS             complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="ACG930_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFQ0518368.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="ACG930_001198"
     CDS             complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="ACG930_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFQ0518369.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24673..25311)
                     /locus_tag="ACG930_001199"
     CDS             complement(24673..25311)
                     /locus_tag="ACG930_001199"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFQ0518370.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25312..25962)
                     /gene="rpe"
                     /locus_tag="ACG930_001200"
     CDS             complement(25312..25962)
                     /gene="rpe"
                     /locus_tag="ACG930_001200"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFQ0518371.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="ACG930_001201"
     CDS             complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="ACG930_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFQ0518372.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="ACG930_001202"
     CDS             complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="ACG930_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFQ0518373.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29105..29845)
                     /locus_tag="ACG930_001203"
     CDS             complement(29105..29845)
                     /locus_tag="ACG930_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFQ0518374.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="ACG930_001204"
     CDS             complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="ACG930_001204"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFQ0518375.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31216..32154)
                     /gene="fmt"
                     /locus_tag="ACG930_001205"
     CDS             complement(31216..32154)
                     /gene="fmt"
                     /locus_tag="ACG930_001205"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFQ0518376.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQVVHDFLNGSGQQVQIGQQVK"
     gene            complement(32147..32638)
                     /gene="def"
                     /locus_tag="ACG930_001206"
     CDS             complement(32147..32638)
                     /gene="def"
                     /locus_tag="ACG930_001206"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFQ0518377.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32653..35061)
                     /gene="priA"
                     /locus_tag="ACG930_001207"
     CDS             complement(32653..35061)
                     /gene="priA"
                     /locus_tag="ACG930_001207"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFQ0518378.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35314..35619)
                     /gene="rpoZ"
                     /locus_tag="ACG930_001208"
     CDS             complement(35314..35619)
                     /gene="rpoZ"
                     /locus_tag="ACG930_001208"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0518379.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="ACG930_001209"
     CDS             complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="ACG930_001209"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFQ0518380.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9887 a         7988 c         6705 g        11989 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaat
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttatac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct
    18001 ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc
    18061 atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa
    18121 atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc
    18181 caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg
    18241 agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc
    18301 aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac
    18361 tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc
    18421 tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata
    18481 tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat
    18541 cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg
    18601 caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg
    18661 agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat
    18721 attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac
    18781 ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt
    18841 gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat
    18901 gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc
    18961 tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt
    19021 ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc
    19081 cttccttaaa aagaactcta aaaatttggc gtagcccaga tggtcgatac tcaccatact
    19141 tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca
    19201 gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa
    19261 gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt
    19321 tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat
    19381 cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg
    19441 aagggagttt tttcatgagt tattcattaa attggaatct agattctatt ttttccggag
    19501 gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt
    19561 attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta
    19621 ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg
    19681 cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg
    19741 caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat
    19801 ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt
    19861 taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa
    19921 atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca
    19981 gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct
    20041 tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg
    20101 aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt
    20161 ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt
    20221 acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac
    20281 aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat
    20341 ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg
    20401 acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat
    20461 ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc
    20521 ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca
    20581 gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca
    20641 gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag
    20701 caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag
    20761 aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata
    20821 tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct
    20881 cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt
    20941 tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac
    21001 cgttttataa cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg
    21061 ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct
    21121 caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt
    21181 tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag
    21241 aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta
    21301 actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa accattgaac
    21361 tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc ctccgcctaa
    21421 agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt ctccagcttt
    21481 tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc aaccaccgat
    21541 gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt caaagccact
    21601 tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt ctgctacgat
    21661 tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt ttggttgttc
    21721 aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc ctgtatcaac
    21781 actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg ttgttgaaga
    21841 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg ttgattcttc
    21901 tgttgctgaa gattcaggcg ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    21961 tgattcttct gttgaagatt caggtgttgt tgattcttct gttgctgaag attgtgtagc
    22021 tgatgatgat tcttcagtca ttgaagattg tgtagctgat gattcttctg ttgctgagct
    22081 ttgtgcagta gatgaagctt gagtagcttg tgcttcagcc tctgcttgtt cgcgtgcttc
    22141 tttttcagct ttttcttgtg cagcttgttg acgagcttgt tctgctagac gttgttgttc
    22201 acgaatacga gcttgctctg cttcagcttc tgctttttga cggttcaagt cagctttctt
    22261 gtcttcagca gttgcttgtt cagcagctaa tgaagttttc agtacgttca aatcagcttg
    22321 tttagataaa agatcgcctt tttgagattc caaagcagct tggttttcag ctaattcttt
    22381 tagtttagca tcgttttcag cttttttgtc ttctacagct tttttatctt gtttttgttg
    22441 ttccatcaag tcgttgtttg cttttaccat cgttgtcatt gcttgaacgc gtccaatagc
    22501 atctgctaat gaatcagcat tcaatacagc atcgatgtag tttgagcttg tgttgcttac
    22561 ttgtgcttcg cgtgcttgtt tttggattgt atcttcacgt ttttcaatac gttcttgtaa
    22621 atctgcaatg tcttttacta attgtgcaga ttcttgacgc aatgtatctt gttttgctaa
    22681 taggtcttgt gcttgtgtgt tgatttcaga aacttggctt tctaaggcat cgatttgtga
    22741 ttgtgcatct gcttgttgat ttttcaagtc tgcaatcttt tgatcttgct gttgtatctg
    22801 agaatcaaaa tcgtccgccg cggcagcgat cggtgatgct acggcagtca aggtcattga
    22861 acataccatt actgctgata ttaaactctt tttcactctt cattcctccg actggcttaa
    22921 tttaataaat atctaaatat atttaagtct ttcttaacga tataaaaatt gtaccatagc
    22981 agtgtgtcaa cgatataata gttatgttac aaaaatgttt caaaacaact tttaaaaatg
    23041 acaaaactgt tcgtttcaga aaatgatcat gaaaaagccg cgttaagtct agcatttctt
    23101 aagataacaa cgattctttt tcgctttcga cctaaaaata aaaaaagaaa ttattcatca
    23161 ctgaataatt tcttaaaggg aaaaatgaat aatacaaata taatcatgtt caacagcagt
    23221 gtaggtccta aaaaccttgt aataaaatac gtgttattta ctactgctaa tttaaaaatc
    23281 aactggacca ccatcgtaaa caattcataa cccgtgacaa agatgatcat actgaaaaat
    23341 tcagtaaaga tgttgacatg gataacgtct ttcattacat acatcaacca tacaattaaa
    23401 gggagagcta ctgcatagat accgataacg ccaatatagt aagcgtcata gatagccccg
    23461 agaacaatcg tggtaatcag taaataacgt ttttcaaacg ccatactgca acataataat
    23521 gccaatatca gaaagtgggc atttgacata taggtgcctt tcgaccactc ccctagcatt
    23581 cttgttaaat gaccatctat caacatcaaa aagaacaaaa cgattggcag atagtacttc
    23641 attgtttctt tcttcaacat ggactaatcc tccgctagcc gttggacaat cgtcacaact
    23701 gacacgtcat acatttctgc ataaggtttc acataaactt cccgatccag cccataacta
    23761 tctggtttcg ttttaataac cgtaccgatc ggcaagttag ctggagaatt ccctccaaga
    23821 ccggatgtct ggacaacatc cccttctttg atatccgtat caccagttaa ttgggtcacc
    23881 actaaggcat ggagcttttc atcatagttt ttaagcaaac caaacgcttc gccattagcc
    23941 gaagataccc gtactggaaa atgattggag ctttcattag aggatgacag taattcgatt
    24001 ttagacgaag ccgtattgac ctcgatcact cggccaatca atcctttttg cgacatgact
    24061 gccatatttg cttcgatacc gtctttagaa cccttgtcta cgatcagcat gtcctgccaa
    24121 ctgtcaggcg aacgagtaat gacatttgcc gttacttttt cgtaactagt cagcgtctga
    24181 ttcaactcaa gttctttttt caacgcttcg atttctctct cgtaattctt gttttgctgt
    24241 gaaacgtcat catagctatc gattttttct tttagccgct cattttcggc ataagttgaa
    24301 aaaagattat ggacagaatc tactccattt cgtacccacc gtactggggc agagattgtt
    24361 ttatcaacca ttgcaacact gtcattaacg atggattgga agaaattggg ctttccttca
    24421 ttcgctcgct gcgcagcggt cacacttagt atcgtcacca cgatgataac aataaccaag
    24481 gtaataataa tatttttatt aggattgaac ttcttcacaa agacacctcg aattaattag
    24541 actcttgtgt tcaattttat cactaaatgc cgtgaaacaa aaggtaagtt gctcctctta
    24601 agcttttttt tagcaaataa tagattctgt catttttagc ctgaaagaca aattttttta
    24661 tttgtttatg gatcaatctt tgctttgaat aactgcaatc ataccatctg aaaaagaaaa
    24721 ttctgcggta tctgaaagaa attcgttact tgcataagat gtcggatatt ctacttcttt
    24781 attttccaat acatacttgc tgccttttaa tgtaagattc gagacgggag tcaagcagca
    24841 ataagctaaa tacttcatat ctggtatctg tcttactata tgctctccag gcaaataata
    24901 agacaaataa ttttgacaat ctctgataat aagctgatgg gcaaagggtt tgaagcgagg
    24961 ttccatacct aaccagagat tggctaaaag atgatccaat cttccgcccg tagctccaat
    25021 caaagtgact tccgcttgcg ggtaacgttc aaatgttttt aagataccta actgtgtatc
    25081 tgtatcgtct ttttctgcag gggaacgggt atactctttg gcttttgcaa atacttcctt
    25141 ctgctcttcg ttcgacaatg aatcaaaatc gcccactgcc agatctactg ggtagcctgc
    25201 ttgaagcagg tacagcgcac cacggtctat cccgacatag gcatcgtatt tggacagcag
    25261 agactgcggc cagttttgcg gattacctcc agcagctaat aaaattttca tttagtctaa
    25321 tgcctctttt aatcgttcga tttgtccgac tggattttcg gctccataga tatatgatcc
    25381 tgcaacgaag acatccgccc ctgcatcttt acagattttt gctgtttctg gaacgattcc
    25441 gccatctact tcgattgcat aagtccaatt gttctctcta cgtagatcag cgagttccgt
    25501 aattttttct actgtttctt caataaagct ttgtccgccg aacccaggat tgacagtcat
    25561 gactagtact tgatcagcca aaggcaaaac atgtttgatc atggagactg gtgttcctgg
    25621 attgataact actccagctt taactcctaa gctttttgtc atttgaagtg cccgatgaat
    25681 atgaggagtt gcttcgacgt ggacagtaat gatatctgct ccagcttttg caaatgctgg
    25741 aatgtagttt tctggatcaa cgatcatcag atggacgtct aacggtaatt tagtaacagg
    25801 acggattgcc tgaacaatat ttggccctaa tgtgatattt gggacaaatt ggccatccat
    25861 tacatctacg tggatgtaat ctgcgcctcc tttttccact aactcaatgt ctctttgtaa
    25921 attggcaaaa tctgcactca aaatggatgg tgctatcttc attcttgttt cctcctattt
    25981 tcgtttacct tctttttttg catacattgg ttttcttttt tcgatttctt gtaagaattg
    26041 caaataattg tcgtaacgtg tctgtgcgat accacctgtt tctactctat gttttacttc
    26101 gcagccaggt tctttagcat gcatgcactc tctaaatttg caatggacag aagcttctac
    26161 aaattcagga aattgtctcg gcagttctcc tgcttcaatt gtcaaaaagt caatcgagct
    26221 aaatcctggt gtatctgcta ctaacccgcc atagatagga atcagttcca catgacgtgt
    26281 tgtatgccgt cctcttccaa gtgcatcaga aatctctcct gttgctaaat tcagttccgg
    26341 tgatatttga ttcagtagcg tcgattttcc tgctccagac tgacccataa agaccgatag
    26401 ccgttctggg aagtaacgga tcagttctgt cgtatcaccc gtatgattgg gtacaatcac
    26461 cggatagcct attttagtat aggtttgctt gatctcttcg attttttctg ggtcgtctga
    26521 caagtcggtc tttgtcaaaa aaataatcgg ttcgatcgac tcgtattcca aggtaactag
    26581 aaagcggtca agtagattat aagaaaatgc aggctctacg atacttgtga caatgattcc
    26641 aagatcaaca tttgtgactg gtgggcgaac taattgattt tttctcggca agatttccag
    26701 aagatagccg tctgtttgat tttcactctc aaagatcacc tgatctccga caagcggcgt
    26761 gattttccga ttccggaaat ttcctcttcc tcttgtttga taggtctctc cgtttgcgta
    26821 tacatagtaa aaaccgctga ttgcttttct gatttgtcct ttgataagtg ccacctccgt
    26881 ttttgtttat tttaccatac gaagaggaaa gtaggtgtta ttccatgcaa acttctcaaa
    26941 gtatatggct tgaaaattga tcaaaagaga tagaaacaca aaaaagagaa tgcaacaaat
    27001 caatgtcgca ttcccttctg atatatttta ttcagcactt attttgaact ttctgaggtg
    27061 ctagctgatg aacttgtgga gctggaagat tcttcttttg aagagttgct tgtgctactg
    27121 gagctacttg agctgctaga actgtctgaa gagtcttttt cagaactaga agacgctgga
    27181 tctggtcctt tagagtaaat tacgttcaca accattcctt tggtaattgt cgttcctgcc
    27241 cctggtactg tacgaatcac tttatcttta tccaccgtgt ttgaatattc ggaagtctca
    27301 tgcccgatat attctgcacc gacactagct aaataacttt gtgcttcgct ttttgtatag
    27361 ccggagatat cattcaattt aggctctgtt ccttggctta cgacaaaatt gatgtaagtt
    27421 tcttctgcta caacttcacc cgaggctgga tcctgactga tgatcgaacc tgatggtaca
    27481 gtgtcgctat agtcataagt agcactaata ttattgatat tgaatccttg tgtaacaagc
    27541 caattacgaa cagtttcgta gttttctcct acatgactac tcaaagtcac tgtttctggt
    27601 cctttgctga ctgtgaaagt aatcgtgtct gttttaggat cgacttctgt atcttctgat
    27661 ggagattgcg aaatgatcat tccgctttct acctctgaac tgaattcctc ttctttttga
    27721 atcaagtcag cagaaaaccc taattctttc aaacttgctt cggcatcttc ataactttta
    27781 ccactgtaat catctaattt gatttttttc gtgccgctac taatatacag agtgacttcg
    27841 cgtttttgct tgactgtcgt tcccgctgcc gggtctgtct tcactacatt accttcttcg
    27901 attttgtcat ctgcaatttc ttctgttttt gttgctactt ctaatttcgc ttttgcgagt
    27961 gtttctctag cagaagcttc agaaagatca gaaacatcag gaacaacaac ttctcctcgc
    28021 ccgccagaag caaagaatac agctgttccg attcctaaaa cagcaagaat agctaatagg
    28081 atcagccacc attttttctg tcctttcttt ttaggatcag gcagaacttc ttcctcctct
    28141 ggcaaggttt cgttttctgg cttgtctttt ggcagaggca tagatttgaa tgaatcaggc
    28201 attggtgcat cttccgtaag gggtgtgata acttttgttt cattatccat cacatgaggc
    28261 tgccattttt cttcgtttgc acgagctggt gataatactg tagaaagatc atcagacatt
    28321 tcctcggctg acttataacg gtctgcaggt tctttagccg ttgcccgtaa aatcacgttt
    28381 tccagtgctt gtggcacatt tggatcaagt gcttttatag atggaagatc atcttgaaaa
    28441 tgttttaaag caattgttac agcagattca ccatcaaacg gtacgctacc cgtcaacatc
    28501 tcataaagga tgatccctaa agcataaata tctgactgct tcgttgccat acttcctctg
    28561 gcctgctcag gggacagata atgaacagat cccagcatcg tattcgtctg cgtgatcgat
    28621 gtttcagata aagcgatagc aatcccgaaa tccgtgattt ttacaacacc ttcattatcg
    28681 atcagtacgt tttggggttt caaatctcgg tggatgattt gatggttatg agctaaagaa
    28741 atagcagaaa ggatctgctg cataatattt actgctgttt cataaggaac aggataatgt
    28801 gtttggatat atcgtttcaa gtccattcct ttgacgtatt ccatcaccag atactgcatg
    28861 ttgtcttctt caccaacatc gtaaacacta acaatgtttg gatgaacgag ttctgttgct
    28921 gctaaagctt ctctctgaaa tcgtcgaatc gcagtctggt cattttgaaa gtcaaatcgt
    28981 aagactttaa ctgctacatc acgatccaag attaaatcgt gcgccaaaaa tacatttgcc
    29041 ataccaccgc taccgatatt tccagtgatt tgataacggc catttaattt tttgcccaac
    29101 tcgatcatac actgtcctcc ttatattcga taagaagaac ggtgatatta tccgctccgc
    29161 ctgcttcatt ggcacgatca atcagctcag ttactttatg agacaatggg ccttcttgat
    29221 tgatgatcgt tcctatttct tcttcagaca gcatgttcgt caagccatct gaacataaca
    29281 gcagtcgatc ttttagttgc caaagatgag tagaaacatc tacttcgact gttccaggca
    29341 tgccgacaga acgtgttaaa atatttttcc ttggatggtt cactgccatt tcttcgctga
    29401 tttctcctga tttgactagt tcattgacta aagaatgatc ctccgtcaat tgcatgattt
    29461 tatcttcacg aatcaaataa gctctgctat ccccaacatt ggcaatcgtg aaccagtcat
    29521 ctgacagagc ggccgctacg attgttgttc ccataccgtt atattccggc tgttcttgtc
    29581 cacgctgata aatcagcata ttttcttctt gaatcgattg aatgaaccat tgggcgattt
    29641 tttcatcgtc aacagcttct tgtttttccc aagcttcgcc tagattcgtt accgccatct
    29701 gactggcaat gtctccggca cgatgaccac ccatcccgtc tgctaataca gcaagcttga
    29761 gacctgaacg gctggtaaat acactggcat agtcttgatt tgtgttacgt cgtcttccta
    29821 catctgattg atattcaatc tgcatttttt cacctcatta ctttttgcgc aaacaacaaa
    29881 tgaaaaatcc atctgtgtaa aactgatgcg gatacaaagt caacattttc tcttcgattg
    29941 atgattgtag cataggattg gtcaaaacat caatcctctc aaaatcaggg tgtctttcca
    30001 agaaagcaga aacaacgtct tggttttctt cttttaagat cgtacaagtg ctataagtca
    30061 gaataccgga agactttaaa gttggtgcgc agctttctaa aatttccaat tggatttttg
    30121 gtaaattcgc taattcatcc ggctgttttt tataacgaat atctggtttt cgccgaagca
    30181 gcccaagacc tgaacaaggc gcgtctacta aaatccgatc aaactgctct gcttcgaact
    30241 gtttactgac ttctctagca tccatctttt gagcgtagac agcagaagag acacctagac
    30301 gtgctgcatt atcttcaatg agtttgactt tgtgttcgtg tacatctaaa gcgaccactt
    30361 ctccaccgca tgacggatct aaaaaagaag caatatgcgt cgtcttacct ccgggtgctg
    30421 cacaggcatc taagacatga tgttcaggct cgatttgcat agacggcgct acaagcatcg
    30481 aactttcatc ttggatcgtc atgacgccat cgtggaacaa tgagctagaa gctaaatgcc
    30541 cttttttcgc tactataccg tatggactga cttggctttt ttcagctgtg atctcttctt
    30601 cttgcaaaac agtgatggcc tgatctctgg aaagtcggcg tgtatctact cgggcactag
    30661 catggctagg ctgatatagc gataaaccga gcttttcagt ttcttcgtat ccgatttgat
    30721 ccaccagtcg tttcgtcatc catagaggca ggctgatttt gacagaaagt ctttcgatag
    30781 gatcagcaat gccttgcaga tctggtgctc cttgacgctg ataattcctc aagacaccat
    30841 ttacaaattt ccctgtccca ggatttcctt ttacttttgc gatttcgacc gcctcgttta
    30901 aaatagcatg tgcagggact ttatctaaaa attctaattg gtatacagaa agataaagaa
    30961 gcgtcttgac ccagtcatcc actttttttg ctttagcgat caatggtgca acgtaaaatt
    31021 ccaatagtcg ctgatggcta atcgtaccat agatcaattc tgtaaataaa cccacatctt
    31081 tttgatttag ctcgctttgt ttgatcatct cattcaacaa aagattcgag taggcgccac
    31141 ccttgttcac tcgctctaat gtcagtaatg ccatatatcg tactgatttt ttcatttttt
    31201 tagggatttt tttcattatt tcacctgctg accaatctga acttgctgac cgcttccgtt
    31261 aaggaaatca tgtacgacct gttttccttt accagctggc tgtaattcat tgatggctaa
    31321 gacggtctgt ttaccgcaag caatccatag attttttttg tctttccgga tgatcgtacc
    31381 aggtgctttg tctgtagttt ctgccaatac ttcaaccgat aataatttcc agcgtatgcc
    31441 ctcataggtc gtgaatgcaa ttggccaagg acgcattccg cgtacttggt tgtcaatttc
    31501 ttctgcagtt ttatgccaat cgattgcttc ttgttcccgt gtgatgtttg gcgaaaaagt
    31561 tgcttctgac tcgtcttgag gtactggttt ttgtccatcc aaaatattgg gcaatgtttc
    31621 tagcaatagc tttcttccta aaaggctaag cttttcaaac atcgtcccta catcatcttg
    31681 tttagtgatt ggtatgcttt cttgcgcata gattccgcct gcatccattt ttttgatcat
    31741 ttccatgatc gttacaccag tttctttctc cccattcatg atggcataat gaacaggcgc
    31801 acctccccga tatttaggaa gtaaagaagc atggacattg attgccccta attttggtac
    31861 ttgcaataac ttttcaggca agaattggcc aaatgccgca gtgacgatca catcaggcac
    31921 caattcaatg atttcttcca tttctggcga accggagatt ttctctggct gcagcacacg
    31981 gataccgtgc ttcagagccg cttcttttac cggtgtcggc gtaattactc gtttccgccc
    32041 aactggacgg tcgggctgtg ttaccactgc ctggatctcg taacctgatt ctatcagccc
    32101 ttcaagaatc ggcacagaaa aagcaggtgt gcccataaat actagcttag tcatcaagat
    32161 gttcctccat atattcttca agttcttctt ccgggatctg ctgtatcatt ttctcaatga
    32221 acaagatacc gtctaagtga tcgatttcat gctggaaggc acgggctaaa tagccaaaag
    32281 ccgtcacttc tatctcttct ccgtctcgat cataataacg cacggtcact tcatctgctc
    32341 gcttgaccgt tccatagaca tgcggaatac tgagacaacc ttctacgtca aggctttcac
    32401 cttttgcttc gatgatttct gggttaatca gttcaaattt ctcgccttca tctacttcga
    32461 tcacagcaat tctcttgttt tgtcctactt gaggagcagc gatccctatt ccgtcattcg
    32521 caatcattgt ctcatataaa ttgtctaata aagcgattgt ctcgtccgtg attacatcga
    32581 ttggctgagc agttcttttt aatttatcat tagggtggat caatatagga tagcgcataa
    32641 tttggccctt tcttaaataa agtttaatgg ttcgttgtca attgccacaa aaagaccttg
    32701 tcgctgttct ttctggcttc cattcaaaat ttcatccaaa acatgaggaa gattcggttc
    32761 atgtttatat ttgatgatta gttgataata atatcggttt ttcactctca aaatcatgct
    32821 gggcgttggc cctaatagca agctttgagg gcttaacact tcttttagct gattggcaat
    32881 ctgaaagatt ttctttgccg ctacttgttc ttcaggatgg ctggcggtta ttttcacagt
    32941 aaagtaataa ggaggatagc ctccacgatg ccgtacatgc atttcctgct gataaaactg
    33001 ctcataattt tgttttttag ctaattctat ggcgtaatgt tgaggattga atgtttggat
    33061 cacgacttcg cctgcttttt ccgctcgccc tgctcgtcct gaaacttggg taagcaattg
    33121 gaatgtatgc tcactagaac gaaaatccgg taaattcagg gaggtatcag cattcaacac
    33181 cccaactaat gtcacttctg gaaagtccaa acctttagca atcatttgtg tccctaataa
    33241 tatatctgct tcttttgcac cgaatttttg taaaatctgt tcgtgtgccc cttttcttcg
    33301 agtggtatct acatccatac gcaaaatcct agcttgcgga taaagttctc ggagttcctc
    33361 ttctactttt tgagtacctg ttccatagta gcggatttta ttgccgccac aattaggaca
    33421 gcgattggga ataggttctt catgtccgca ataatggcag cgcattgaac gtgtatccat
    33481 atgcagtgta agagagatat cgcaattagg acatggaaga acaaatccac agtccctaca
    33541 catcacaaaa gacgaatatc ctcgacgatt gagcagtagg acagtttgtt cttttttgtc
    33601 taatcgattt tgtatttttt cctgcaaatt agcagaaaaa gtagaggtcc gatgattctg
    33661 aaactcttca cgcatatcta cgatctcaat agctggaagc tgtgcagctg ctttggctcg
    33721 gtggtttaac tgcaataact gataaacgcc tttttgagct cgtgctcttg attctaaaga
    33781 gggcgtcgcg cttcctagaa ctattgggca atgatgatat ttactgcgcc aaattgctag
    33841 atctctcgca tgataacgcg gtgtctcatc ttgtttgtaa cttgattcat gttcttcatc
    33901 gataatgatc agcccgatat ttttcagcgg ggcaaaaata gcagatcgtg cgcctactac
    33961 tacttgcgct tcttcccgct caatcttgcg ccattcatca tatttttcac cttgggaaag
    34021 tccgctatgt aagaccgcaa ctgattctcc gaagcgtcct ttgaatcgct cgaccatttg
    34081 cggagtcaat gcgatttcag gcactaacat aatagccgtt ttattttctg acaaaacatc
    34141 agcgattgcc tgaagatata cttctgtttt cccgctgcca gtgattccct ccagcaaaaa
    34201 gacctgatct ttttgctgct gacctgctgt gatgatttgt tcgacagcat ttttttgttc
    34261 tgcattcagt tccaatgccg tcgtttggtc aaatactcgg tctttataag ggtcgcgata
    34321 acgttctgat tctataaact ccagccagcc cttttctttt ccttgattca agacagcagt
    34381 actgattcct ttatttttga aataagcaat tggttcttct tggctcagtt cagataaaca
    34441 caaaagaagt tctttttgtt tcttggcatt ttgccgtaat tttgcccatt cttcttcgat
    34501 ttgcttttca gttaacaaag aacggaccaa acgaatcgtt tttactttat ttcgtgtatg
    34561 gacttcatat ttgatatcta ctaattgctc ttggcgccag cgaatcaatt gagaaaggct
    34621 gccttcttct tctgcttcct tccaggaaat cacttctcgc tgatcaaaca atacctgaac
    34681 ttctggtgtg tctgccaaag gatagatcaa tttatcatat tctgctttca tcacactcgg
    34741 aagcatcgtt tgtagacaag tgattttgaa tgcgtaagta atttttttca tataatcagc
    34801 taatgaaagt aattcttcat tgaccaccgg agcaaggtct agcaaacgaa taactgcctt
    34861 caaagatgga ttagctgatt cttctgattt ttggatagcc ataacaaatc cttggacatg
    34921 acgattgcca ttaccaaaag ggacttctac tcgcatcccg acttgcaaag ctgtttccat
    34981 ttcagaggga accaaataag tgaatggctg atcggtctgc atagtaggta cgtccacaat
    35041 gacttcagct gttaatgtca tggttcgttt cctccttttt ttgtcttttc ttatcaagcg
    35101 acaaaaagtt ccttgcctat tttactagag atcgatggat ttgtcttatc ttctgccaaa
    35161 tcctaacaaa aaattaacag cagataagaa aaaaaagaac tgtgtcaaaa agttcagaca
    35221 cagccttttc taccagacaa taagtggcga atgtttgaaa aggaaacagc tgggtttgct
    35281 tttcttttta gatgttcgct ctatttttct ttattacatt ttttgctctt cacggatacg
    35341 tgattccaat tcgtgttgtt cacgctcttt ttgtgcttga cgttcctctt cttccatctt
    35401 caaacgttca cgttttaatt caggatgtgg atcattgact acatttcctg catcgatttc
    35461 ttctaaagct tgaccgacgc tttttactga atcaaaagaa tctagagtag gctgtgcact
    35521 tgcatccaat tcatgcgcgc gtttacttgc taaaatcact agagaatatt ttgaatttac
    35581 acgatctaat agtgagtcaa ttgaaggttt taacatcata agactacatc tcctttaaca
    35641 ttttaatata tttaccgatt acgcgatcta ctcgaaaatg ttcactggca ataatgtttt
    35701 tgattcgttc aactgctagc ggcacttcat catttacaac agcatagtcg taaagagcca
    35761 tcatttcgat ttcttctttt gcaactttca ttcgttcttc gattacttca tctgcatctg
    35821 ttcctcggcc tacgatccgt gattttaatt ccgctaaatc tggcggagtc aaaaagatga
    35881 atacaccatc gggcactttt tctttgactt gttttgctcc ttggacttca atctccaaga
    35941 aaacatcttt tccttcatcc aatgtcttgt tgatatatga caaaggagtt ccataataat
    36001 tcccgacata ttctgcgtat tccagcatct ctccagcttc gatcattgat tcaaactctt
    36061 ctttgcttcg gaagaaataa tcaacgcctt cgacctcccc ttcacgcatt ttacgggtag
    36121 tcattgagat cgaatactga aaatcattat cctcactctc aaaaattgct tttcgtactg
    36181 tgccttttcc tacaccggat ggaccagaca acacgattaa taatccacgc tctgacatga
    36241 cgacgtcctt tcaactagtc tttttgtact tatcgtttat tttgcacttt ttttctgcaa
    36301 ctttcaaggt tatctttaat tatagctaga aattggtaaa aaagctaccc tgtaccaaga
    36361 ggtcgtaaaa aagctgtcct gcatcaagta ataagaacag ccaaacataa acagcttctc
    36421 atgtttttcg tttggttggg gttattatcg cagatgcaag cttttgaacg ccgtgtataa
    36481 gaggtcgtga agaagccgat tagtttcgag tatgaagaaa aattttgtga aaatagtttc
    36541 tcacattttt gcataaattt ggcttaata
//
LOCUS       DAZKPE010000022        35882 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000022 DAZKPE010000000
VERSION     DAZKPE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.022"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1152
                     /locus_tag="ACG930_001210"
     CDS             <1..1152
                     /locus_tag="ACG930_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HFQ0518381.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="ACG930_001211"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="ACG930_001211"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFQ0518382.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="ACG930_001212"
     CDS             2728..3003
                     /locus_tag="ACG930_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFQ0518383.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="ACG930_001213"
     CDS             3009..3776
                     /locus_tag="ACG930_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFQ0518384.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="ACG930_001214"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="ACG930_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFQ0518385.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="ACG930_001215"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="ACG930_001215"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFQ0518386.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="ACG930_001216"
     CDS             7920..8222
                     /locus_tag="ACG930_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFQ0518387.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="ACG930_001217"
     CDS             8225..9388
                     /locus_tag="ACG930_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFQ0518388.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="ACG930_001218"
     CDS             9414..12842
                     /locus_tag="ACG930_001218"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFQ0518389.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="ACG930_001219"
     CDS             12863..13987
                     /locus_tag="ACG930_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFQ0518390.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13968..14414
                     /locus_tag="ACG930_001220"
     CDS             13968..14414
                     /locus_tag="ACG930_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0518391.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="ACG930_001221"
     CDS             14398..14736
                     /locus_tag="ACG930_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFQ0518392.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="ACG930_001222"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="ACG930_001222"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFQ0518393.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="ACG930_001223"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="ACG930_001223"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFQ0518394.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="ACG930_001224"
     CDS             15893..16936
                     /locus_tag="ACG930_001224"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFQ0518395.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="ACG930_001225"
     CDS             17095..17823
                     /locus_tag="ACG930_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFQ0518396.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="ACG930_001226"
     CDS             17939..18184
                     /locus_tag="ACG930_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0518397.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="ACG930_001227"
     CDS             18181..18399
                     /locus_tag="ACG930_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFQ0518398.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="ACG930_001228"
     CDS             18535..19074
                     /locus_tag="ACG930_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFQ0518399.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="ACG930_001229"
     CDS             19067..21340
                     /locus_tag="ACG930_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFQ0518400.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="ACG930_001230"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="ACG930_001230"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFQ0518401.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /gene="rpsT"
                     /locus_tag="ACG930_001231"
     CDS             complement(22513..22767)
                     /gene="rpsT"
                     /locus_tag="ACG930_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFQ0518402.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="ACG930_001232"
     CDS             complement(23167..23436)
                     /locus_tag="ACG930_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518403.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23698..23826)
                     /locus_tag="ACG930_001233"
     CDS             complement(23698..23826)
                     /locus_tag="ACG930_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518404.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(23906..24361)
                     /locus_tag="ACG930_001234"
     CDS             complement(23906..24361)
                     /locus_tag="ACG930_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFQ0518405.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="ACG930_001235"
     CDS             complement(24499..26427)
                     /locus_tag="ACG930_001235"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0518406.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="ACG930_001236"
     CDS             complement(26624..27457)
                     /locus_tag="ACG930_001236"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFQ0518407.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="ACG930_001237"
     CDS             complement(27649..28353)
                     /locus_tag="ACG930_001237"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0518408.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="ACG930_001238"
     CDS             complement(28376..29002)
                     /locus_tag="ACG930_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0518409.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="ACG930_001239"
     CDS             29328..31703
                     /locus_tag="ACG930_001239"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFQ0518410.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="ACG930_001240"
     CDS             complement(31727..32218)
                     /locus_tag="ACG930_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFQ0518411.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="ACG930_001241"
     CDS             32405..33325
                     /locus_tag="ACG930_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0518412.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="ACG930_001242"
     CDS             33479..33823
                     /locus_tag="ACG930_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFQ0518413.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="ACG930_001243"
     CDS             complement(34013..34513)
                     /locus_tag="ACG930_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518414.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="ACG930_001244"
     tRNA            35041..35124
                     /locus_tag="ACG930_001244"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="ACG930_001245"
     CDS             complement(35448..>35882)
                     /locus_tag="ACG930_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFQ0518415.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11869 a         6262 c         7404 g        10347 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DAZKPE010000023        34983 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000023 DAZKPE010000000
VERSION     DAZKPE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.023"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            60..245
                     /locus_tag="ACG930_001246"
     CDS             60..245
                     /locus_tag="ACG930_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518416.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            257..505
                     /locus_tag="ACG930_001247"
     CDS             257..505
                     /locus_tag="ACG930_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518417.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            536..715
                     /locus_tag="ACG930_001248"
     CDS             536..715
                     /locus_tag="ACG930_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518418.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(758..1228)
                     /locus_tag="ACG930_001249"
     CDS             complement(758..1228)
                     /locus_tag="ACG930_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518419.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            1315..2013
                     /locus_tag="ACG930_001250"
     CDS             1315..2013
                     /locus_tag="ACG930_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFQ0518420.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            2191..2532
                     /locus_tag="ACG930_001251"
     CDS             2191..2532
                     /locus_tag="ACG930_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518421.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            2525..3271
                     /locus_tag="ACG930_001252"
     CDS             2525..3271
                     /locus_tag="ACG930_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFQ0518422.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            3277..3963
                     /locus_tag="ACG930_001253"
     CDS             3277..3963
                     /locus_tag="ACG930_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFQ0518423.1"
                     /translation="MFKPLIDSYSAVLRRFKGNQIVARINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GVDIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLSH
                     ETIKKLRIGG"
     gene            3966..4796
                     /locus_tag="ACG930_001254"
     CDS             3966..4796
                     /locus_tag="ACG930_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFQ0518424.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLIEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            4813..5664
                     /locus_tag="ACG930_001255"
     CDS             4813..5664
                     /locus_tag="ACG930_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0518425.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPSHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            5661..6020
                     /locus_tag="ACG930_001256"
     CDS             5661..6020
                     /locus_tag="ACG930_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HFQ0518426.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            6035..6196
                     /locus_tag="ACG930_001257"
     CDS             6035..6196
                     /locus_tag="ACG930_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0518427.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIVNL
                     RREIRRLEE"
     gene            6199..6498
                     /locus_tag="ACG930_001258"
     CDS             6199..6498
                     /locus_tag="ACG930_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518428.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRRIAIWHGDRILVTGTAEQLSEITGLSKNTIWDRASSLWIDSKGRQFRYVEEK"
     gene            6498..6959
                     /locus_tag="ACG930_001259"
     CDS             6498..6959
                     /locus_tag="ACG930_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518429.1"
                     /translation="MRTVIQGKEITVTIKSERELDTQEIIAAHQLATGNFEALFIKED
                     SKTSNNNKEVKTKSVEKDIPKWVQVEITCPVCTHESRTTTKYGNVFTKCPSCKTPLYN
                     KYATGIAGEHDKAGNYYYAQEVLRPRNGGLTHEEQELLNAMSQAVTSENNG"
     gene            7016..7831
                     /locus_tag="ACG930_001260"
     CDS             7016..7831
                     /locus_tag="ACG930_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005743 - mitochondrial inner membrane
                     [Evidence IEA];
                     GO_component: GO:0035632 - mitochondrial prohibitin
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HFQ0518430.1"
                     /translation="MNENKLIKLGAAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            7833..7958
                     /locus_tag="ACG930_001261"
     CDS             7833..7958
                     /locus_tag="ACG930_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518431.1"
                     /translation="MGFFMAKILLFLGLVGAAYLVYALLSQTDDKEDDNNDEMKF"
     gene            7970..8284
                     /locus_tag="ACG930_001262"
     CDS             7970..8284
                     /locus_tag="ACG930_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFQ0518432.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            8461..8772
                     /locus_tag="ACG930_001263"
     CDS             8461..8772
                     /locus_tag="ACG930_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFQ0518433.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEEA
                     E"
     gene            8769..8972
                     /locus_tag="ACG930_001264"
     CDS             8769..8972
                     /locus_tag="ACG930_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFQ0518434.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            8969..9265
                     /locus_tag="ACG930_001265"
     CDS             8969..9265
                     /locus_tag="ACG930_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518435.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            9342..9758
                     /locus_tag="ACG930_001266"
     CDS             9342..9758
                     /locus_tag="ACG930_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFQ0518436.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            10017..10169
                     /locus_tag="ACG930_001267"
     CDS             10017..10169
                     /locus_tag="ACG930_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518437.1"
                     /translation="MKLSIEGTSGEIKELLQAIGGSKEQNIKIDDIYKESRDFLINGQ
                     AFAPSF"
     gene            complement(10159..10335)
                     /locus_tag="ACG930_001268"
     CDS             complement(10159..10335)
                     /locus_tag="ACG930_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518438.1"
                     /translation="MLTNEQRAHDLAIATLPFVRDIVKSQIIEGKDAKFDAYFEYIKL
                     YNQFLSAVSEDFKN"
     gene            10676..11107
                     /locus_tag="ACG930_001269"
     CDS             10676..11107
                     /locus_tag="ACG930_001269"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518439.1"
                     /translation="MDSLDFLQNNVVKELKEKGFELEDIQKMTVEDIANNLYYPKFRL
                     EVDSQYGESVLYASEKVVSEKDSFMYTLPNGTLIITKPALSKYIERFVVESRKQHSEF
                     GKPFYIKKRNEPWDQDEECLEYERSILKKRDEKPGPPIRKD"
     gene            11112..11339
                     /locus_tag="ACG930_001270"
     CDS             11112..11339
                     /locus_tag="ACG930_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518440.1"
                     /translation="MRNYWYVSLTNRYPQPNADDPIRVVQSVQIKKKYSIVEMTREAT
                     PKEIDKYNLRYCGHGYWKDEYIQQNIERYIK"
     gene            11336..11620
                     /locus_tag="ACG930_001271"
     CDS             11336..11620
                     /locus_tag="ACG930_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518441.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELATLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            11661..12233
                     /locus_tag="ACG930_001272"
     CDS             11661..12233
                     /locus_tag="ACG930_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518442.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPDALVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWDTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            12234..12545
                     /locus_tag="ACG930_001273"
     CDS             12234..12545
                     /locus_tag="ACG930_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFQ0518443.1"
                     /translation="MIDVSSKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            12536..12796
                     /locus_tag="ACG930_001274"
     CDS             12536..12796
                     /locus_tag="ACG930_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518444.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEGTTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            12957..13316
                     /locus_tag="ACG930_001275"
     CDS             12957..13316
                     /locus_tag="ACG930_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518445.1"
                     /translation="MADLQERNRLVSAEERRLNKLFKDIDKDKKKVVSGLITQAARLK
                     ILLDEMWIDISEKGDYELFSQSENQKPYERERPVAKQYNSRDQAYQRVIKQLTDYLPE
                     EKREPTKNAALDGSDLL"
     gene            13313..14956
                     /locus_tag="ACG930_001276"
     CDS             13313..14956
                     /locus_tag="ACG930_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFQ0518446.1"
                     /translation="MTTLKPFYFDEYVDLYEKGVIPFNKERIQLITYLKNEVLVRDDI
                     YFDEEMIQKFIKYTEKNFFPLAKYQKFITPFIFCYQKEDDEVFFDEILNSIARGGGKN
                     GFMSARDSFFISPLYGVRNYDVTITANSEKQGKVSFKEVYEMVQMRKLEKQFYLTKMA
                     IVNNVTNSIFSYRTNNPKTMDSARDGCLEFDEIHQFESSDLVDIQRSGLGKIKHPRTF
                     YNGTNGHVREGFYDKMLERAQKIFSGENKNDRLFPFICKLDNIDEMDNPKMWSKANPM
                     FEEDSAYSKRLFSTVMKEYKKLEDEPSGRREFVVKRMNFTEGDAESDITTHEKLMATK
                     QELPNLNGRSCVAGFDYASIRDFATVGLLFKIDDKFIWQQHSFARKKFLDTFKLKAPI
                     KDWEKKGLVTIVDEPSIDPRHLIDWLNEKRKIHQIEIVCADGFRMDLLKPLLEKESYN
                     FEFIRNIRGVQSKVAPIIEDGFANERFIFGDDPMMRWYTNNSFIKEDKLGNKTFLKKE
                     PVRRKTDGFHAFLAALYKREEITDMDYEEAFDMLDEIEF"
     gene            14991..16073
                     /locus_tag="ACG930_001277"
     CDS             14991..16073
                     /locus_tag="ACG930_001277"
                     /inference="COORDINATES: protein motif:HMM:NF028182.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phage abortive infection protein"
                     /protein_id="HFQ0518447.1"
                     /translation="MKKRYFLFVTIFIIIAICVLTVFLPQITEYLNYRIFTTKVDDSV
                     TSLSRLEFIKICASVFGPILTVMVFVNTLNMQKKTEQKQNELEVKQAKAENERAKKEL
                     LTQIDREFYFLLNMFIEIQKDQNAKQAVIALQKLAIFNEKGFNQDYAFTSKDLSDSEI
                     GSTIEQSGPLKGTVEYIKFETFDVSKSMGNYQTKTKDVATSLHDQKVAILNEQYEKMQ
                     IYLGRYFKMFHRIVKTLNEYYDDYNDFDVKRYTKYIGTLRTQISPAEFQVILFNSLYI
                     KRGFGLGIQLIGSGFFGDDFDFETNQHFETSINEQWFLSLSTVDSDNSIKRQKLSEYI
                     KELGSVEYKKIANFESLYKLFNETKL"
     gene            16117..17289
                     /locus_tag="ACG930_001278"
     CDS             16117..17289
                     /locus_tag="ACG930_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0518448.1"
                     /translation="MSLFDIFKQSIRNEEPSEWIPDFVYGEEVSARAYLKIMAKNTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWNMSDVIYMEYNNEELERFTR
                     GLFEDYAALFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDRIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIDDVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            17276..17980
                     /locus_tag="ACG930_001279"
     CDS             17276..17980
                     /locus_tag="ACG930_001279"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFQ0518449.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            17985..19145
                     /locus_tag="ACG930_001280"
     CDS             17985..19145
                     /locus_tag="ACG930_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFQ0518450.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTAEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVKYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            19221..19499
                     /locus_tag="ACG930_001281"
     CDS             19221..19499
                     /locus_tag="ACG930_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HFQ0518451.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            19480..19851
                     /locus_tag="ACG930_001282"
     CDS             19480..19851
                     /locus_tag="ACG930_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HFQ0518452.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            19867..20271
                     /locus_tag="ACG930_001283"
     CDS             19867..20271
                     /locus_tag="ACG930_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518453.1"
                     /translation="MSNVKFEGVQETIQALEKKYGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIAEVVRKNATYRDYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSELLYFDAVGEEVKKSL"
     gene            20268..20678
                     /locus_tag="ACG930_001284"
     CDS             20268..20678
                     /locus_tag="ACG930_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518454.1"
                     /translation="MKDMLNIIYEALCLNEYIHSMTYNENTEQYRIKFYEQPETADKT
                     GPMITIRPVDTPNEAYHGSNKELSVEHMIQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFTETNRFVDARRYEGNTKIYDTEY"
     gene            20739..21326
                     /locus_tag="ACG930_001285"
     CDS             20739..21326
                     /locus_tag="ACG930_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFQ0518455.1"
                     /translation="MTLVGFKKMTIGVFDSTGKIPAANLYVIEGEQNKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITALKEMVFPAAGE"
     gene            21399..21866
                     /locus_tag="ACG930_001286"
     CDS             21399..21866
                     /locus_tag="ACG930_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HFQ0518456.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            21912..22220
                     /locus_tag="ACG930_001287"
     CDS             21912..22220
                     /locus_tag="ACG930_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518457.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            22415..29149
                     /locus_tag="ACG930_001288"
     CDS             22415..29149
                     /locus_tag="ACG930_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFQ0518458.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGFTGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRNLATQLPGSHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKILKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKAMDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDSTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDTVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPSDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPKNAKGTNFHP
                     GGAAMVNDQKGPTYEELITLPSGETFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYAD
                     GIGNITTVSSTLNLDALILAINELTTVLRTQLMAGTTDAKDTKLSDETKVADPIIPDS
                     LSEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGAT
                     WNKNLLNGWNSLTGTFIATINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYG
                     SFIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMV
                     GGIGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHE
                     EYVQMPDGRSFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDL
                     LDDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDG
                     AVNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRY
                     TAAANYAFEKFPSKIAYVITNGRVRDRMGLSGTRSSGQWTNWPDGDHFDHIHLNGSMG
                     SGDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGN
                     DGLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIG
                     KGHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGSNKKETKS
                     EINSVDNRHILQAIEKQSRMTNDLLSLLLSFFKSNNRSDKELALDIQKILIRRT"
     gene            29153..30025
                     /locus_tag="ACG930_001289"
     CDS             29153..30025
                     /locus_tag="ACG930_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage distal tail protein domain-containing
                     protein"
                     /protein_id="HFQ0518459.1"
                     /translation="MRTVILRNKLNEEIDLSTEDYFATEMSNLGFEVTKEHIGQWGSF
                     REIGESIELSEFQSSVMISVHGFREQQLYGSLVEFLANGPFELEFSFDSETMIRKCSL
                     KSLSKTEIDSQSSLLTDTLNLYFTSSWYSIKREKLIQNSTSLNTRGKVYSFVRPYVYT
                     KNVWEKKGVFKFSNNSVYLTNSTERMSPLKIRIIGECSNPYWEVIQNSKVVASDGYFI
                     NMKDTQILEVSSLLEDQTAILKDVGGVESSVYQQQDFTKSNFVQAPLGEFSVVFHVGH
                     ANVEIELYEERDLF"
     gene            30022..31071
                     /locus_tag="ACG930_001290"
     CDS             30022..31071
                     /locus_tag="ACG930_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518460.1"
                     /translation="MILAITLFHRDMNLYNERLISTEFEFGTDEIGEEVSNFITDKYV
                     HVKSGDFLLAKFIPSGKIAYFGVISSQEDKKINCKGLLSLADSEIPTVKISGANYEEH
                     IRRLIEYYLLNDPTKQLKNILEVKTESVTSHSYQAVDTNKRRLNAYIINGFKKYNVKW
                     YVKEIKGKKIYTGIRAVDDSIYIKDNSSEFNDWDVFVQSPGPGNENKLLIVDKAMKDI
                     ENPLVLSTWYLDDENNLTQDSTNKNIALPTVNLVNIYDQTQEDRPSYEEVAKSELKGN
                     AYSHEIKVNVVLNARNINVENIETGMLATIVYKEQTYKSVLTAWRISSSKKNIELTFG
                     NVRSRFMDYFEDNGG"
     gene            31075..31899
                     /locus_tag="ACG930_001291"
     CDS             31075..31899
                     /locus_tag="ACG930_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518461.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVGAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIEGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TVTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            31917..33953
                     /locus_tag="ACG930_001292"
     CDS             31917..33953
                     /locus_tag="ACG930_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFQ0518462.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQANDRIDKANDRIDQTNQQIGDLGKLKKMYSNSIDFGDYD
                     YSGNPNLIANINADSFSQGIGALSVIDDGDEVVVTLDPNHKLEVFKAKSQPALLIGKT
                     YTLSVEIMLEDDFTGDPSTIGLRYIKMPNWASELYTRNALTTAKGVWQKLTGTVKITA
                     TSDNAESWLIMLQNKDANNSLSGRLRLRHAKLEEGSTATSYQPNLLDAPYYLSNKPLG
                     ENIANPTVKFPITLSNEALYAKNASEDFVLGETYTVTIKATKPVSQTIRVYLTQKQFG
                     EFKPVEGLVDTWVATVSIKQLGENTKWVYLSQTPNTSLGPVKIDWLKIEKGDTRTPNI
                     SEYKYFGEGLKDSNNPNDYSWDITPEYTEKGLNDTVSLTEPQSIEGLKNFEDGIQSKG
                     KSVLTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNGKSSGGNDSTILTIP
                     EGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            33970..34119
                     /locus_tag="ACG930_001293"
     CDS             33970..34119
                     /locus_tag="ACG930_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518463.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            34116..34562
                     /locus_tag="ACG930_001294"
     CDS             34116..34562
                     /locus_tag="ACG930_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518464.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLANTLDHNDLNNLKAMYEALEHENDNLKQLNAKLMLNDVAIK
                     QENTALKEKADSLAQINSKTMLASLQNSKDIAEIKKQLNPESEGGE"
     gene            34564..34701
                     /locus_tag="ACG930_001295"
     CDS             34564..34701
                     /locus_tag="ACG930_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFQ0518465.1"
                     /translation="MFSFSDVKMMFDWSCFTEEQVREFVPLCITDEEADKIISKEESA
                     S"
     gene            34739..>34983
                     /locus_tag="ACG930_001296"
     CDS             34739..>34983
                     /locus_tag="ACG930_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518466.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLV"
BASE COUNT        12695 a         5292 c         7471 g         9525 t
ORIGIN      
        1 aacgaatatt agctaatttt ttagcttaca gattattttt ttagaaagga gctattttta
       61 tgtctgagaa tttagactta aaaattcgag cggagatgag aaaaagaaga atgactttca
      121 aagaactagc tgcgcttatc ggtatttcag gagcttattt atcagatatt ctaaacggca
      181 atcgtgatgg aaagaaagca caacagcata tcgaaacagt gaaaaaaata ttggacatcc
      241 gatagggggg taggcgatga caaaactaaa aaaacaagat tttgtaaaaa aatacaatta
      301 ttctccatct acttatcaac gtcgaatgtc ggaactaaaa aatacagcaa ttttctcagc
      361 ggcgtatgaa cgggtcacag gacaagaagt ttggatcaat acagaattat acgataaatt
      421 tttgtctttc aaatcctata acaggttacg cacaagaaag gtaacaccta aagaatttat
      481 cgagaagcat ttagttgatt tataaaaaac agaacatttt gagaggtgaa ggttaatggg
      541 taaattcaac agagcattgg tattcagcgc accgctaatc atctacgctt taggactttg
      601 gggaagcagg caagcgttga taggaacgat tgtttacatg gtttggattt ttatggggct
      661 tgatgaagct gaagctgagt acagagcgaa aaagccaacc gagggggctg actaaaaatg
      721 aatagaaaag agaaactaga atgtatatta ctattactca gtttaattct ttcactaatt
      781 tctctattgg gaagtttgta tttttgatat caacaatttt gtggatttgg gttctattta
      841 gagtaaatat catttttgtt tggtgattaa ggagtttatt aaaattaatt ttccctactt
      901 caaatgcaag gtaacaagat atagcacttt taggaggaat atttagcggt acagcttcag
      961 agtatattct attatcatcg actgatcctc ctttagcaat taatttctta aatggagtag
     1021 ctgaccatct gcggtttaag ttagcggatg aaagttctaa attaactaac atagctggtt
     1081 ctgttgaata gttagaaatg attacttttg tataaatcat atctgcagcg aagtaagaag
     1141 cattaagttc aacttctagt tgagggcgca ttccttttat ttttatccct gttaaaaacg
     1201 tactcaatat aaaacttatt attgacatcc attgaaaaat tgttaagtga aaaaaattca
     1261 aaataaacac caccagtttt taactaaatt ataccaaaaa ggagagaaga aataatgcaa
     1321 gaattagtaa ttttgaaaaa taaagaagct gtgactacga gcttacaagt ggcagaaagc
     1381 ttcgagaaaa aacatcaaca tgttttaaga gatattgatg cactaaaaaa agatgtgtcc
     1441 aattttggac agatgtttgt agaaggtaat gaaccagatt catatggcag aaatcgacga
     1501 gttttcttca ttagtagaga tggatttttc ttgctggcta tggggtttac aggaaagaaa
     1561 gctatctact tcaaacaaaa atacattgaa gcattcaacg aaatggaaga tgttattcgc
     1621 aagaatactg ttcctcaaac aattgaagat atgatgatct atcaattaga agaaatgaaa
     1681 gatgttaaaa aagatgtttc catgcttaaa gatactatgc gaattagcgg acaacaagag
     1741 tttgaaatta agcaaaaagg aaatatgaaa gttatgggag ttctaggggg aaaagaaagc
     1801 cgagcttatg aagaaatcag caaaaaagta ttctcaaaat tttggtctga atttaaacgt
     1861 accttttcaa tcccaagata tggcgagtta cctcgtaaga gattcgatga tgctgtttca
     1921 tttattgaaa tgtggttgcc agaaactgcg atccgtatgg aaattgatca actgaacaga
     1981 caacagagac tttttggtga tgacaatgaa tagagctgaa gcgctaagaa tagggacggc
     2041 aattgctaat tgctggtgga aatactataa accaatcatc ctaagccaac aacatattga
     2101 caagcaaaaa gcatggcaac aaataaaaaa gtgactccgc cggcaagcaa agagtcacaa
     2161 agaaaacaca tcataaggag attttagcat atggaaaaag aactttccac tctagatcaa
     2221 tatttgattg atcctgattg gggtaagccg aaaattgagg aaacaagtgg tcgaaaaatc
     2281 agacgaaatc ttttgacgaa tgaagaacta gcttgggatc aagatgattt aggcaaccat
     2341 gtaactattt gggatcatgt ttatcttatc catctatcga agcattcgaa taaacctgaa
     2401 tatatttacg tcatcgaaga tggcttgatt gatgcgctag aagagtacga cagagataac
     2461 ttgattgata tctcttatta cggaccaggt aagaaataca ttgctgaaat ggaggcagaa
     2521 tttgatgagt gaaaaggaac aacctttgaa aaatagaagt gataatacgc tttttaatac
     2581 cttatacaaa ataaatgtga aagatgttac tgaaaaacga aataacctca cttatctttc
     2641 gtgggcatgg gcttgggcag aagttagcaa agtgtgtgag gcagtagatt atgaaatcta
     2701 tcatgatcca gaaacatatc tgccgtatgt ctttgataag aaaacagggt acatggtttt
     2761 taccagtatc acagtcaacg gagtaaagcg tgacatgtgg ttaccagtca tggatggtgc
     2821 aaacaaggca atgaaagatg agccatatac ctacgaagtc aatgattatc agtggaataa
     2881 cgaaacgaag aaaaaagaga ttgttggaaa aatcgaaaag cgagttgaag cagcaactat
     2941 gtttgatatc aacaaaacga tcatgcgctg tcttgtaaaa aatctagcaa tgtttgggct
     3001 agggctatat atatttgctg gcgaagatat gccagaagat gtctcgatgc ttgaaccagc
     3061 tactcaaaga agcaaaaagc tattcttgga tgctttacaa ctggttgcta acaagtacga
     3121 aaaatcaatt gatgaagcaa ttgttgcatt gactgatgca gcttccataa ccgctgatga
     3181 cagtaaatgg accaagagag acttgggcat tctaaaacga ggcgttaatt ggcttgaaga
     3241 tcagtacaga gaagaaacaa aagagaagtg atatgaatgt ttaaaccgtt aatagactca
     3301 tactcggcgg tactaagaag attcaaaggc aaccagatag tggcaagaat caatgaagaa
     3361 gtgaatatcg agcgattgaa gacgatgtat gacggctacg atggcgatcg agtcattgaa
     3421 attcgcttta ttgatccacg tcggttcaca gtacagcaaa gaaacttcat ctatgcgctc
     3481 ataggcgata ttttcatcga tacaggcatg ccaacggact tctggaagga attcttctac
     3541 ttccgttttg aaggtgtcac agggcgcgaa ataagcctca aagacgaatc gaatacaact
     3601 gtgagtgatg ctaatgtctt agcaaatatc atcttagatt tcatctttga acatcatatt
     3661 cctttcaaag aaggctatga gattttacca gcgaatcaag aatattactt ctacaaatgc
     3721 attacaaaaa gagtctgctg catctgtggc aaaacaggag ttgacatcga tcactttgac
     3781 aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatt cagagtacac atttgcagca
     3841 ctctgcagaa tccatcacac agagaaacac aaaataggtg tgatcaattt caaaaataaa
     3901 tatcaaatca aaggaatcaa gttaagtcat gaaacgatta aaaagttaag aataggagga
     3961 taaatttggc tgagataagt tggatcaaac ttaaaactac tatgtttgac gatgaaaaaa
     4021 tacgattaat tcaagctgtt cctgagtcgg atgccatcat cgttatatgg attcgattac
     4081 tagttttagc aggaaagact aacgacgatg gtctgatata tatccagagg aacatgcctt
     4141 ataccgaaga aatgcttgct acattgtttg gcaaaaacgt aaatacggtt cgcttagcgc
     4201 taactacatt ggcaaatttc aacatgattg atctaagcag tgatggacta attgccatca
     4261 gtaattggga aaaacatcaa aatatcgagg gtatggataa agtaaggcta aaaaatgctg
     4321 aaagaaaccg taaatacagg gaaagaaaga gacaggaacg tctcaaattg gaaaatgacg
     4381 ttagcgtgac gtcacgtgac ggtacagata aagatataga agaagataaa gatatagata
     4441 aagaagaaaa gaaaggtaag tattctgacg aacacttacg ccttgctaaa aaattgcaaa
     4501 gtaatttaac tgaagatttt ccaaaagaaa tgaataaagt agatatcgaa aaatgggcag
     4561 acacaatcag gttgattgaa gaaagagaca aagcgtctat agaagcgatt gagtatgtga
     4621 tcaattggct acctacaaat gaattttggt ttggaaatat tagaagtgct aagaaattga
     4681 gagaaaaatt tgagaagctc aaattcgaaa tcaaagcaga caagaaaaat cataaaaagc
     4741 aaagtcaaaa actacagtac agcaatccta gtgaatatga cgacttgcca atttaaaaag
     4801 gagatgcatc acatggaaag cctagcaaat gctatggaga aactaataag aagagtatta
     4861 gtgcaaagcg gaaaatgtcc agaatgtagc gaacctttgt atagttggcg agctaaaaat
     4921 aaggatggtt cagaacgttg taaaccaaca tgcatgagtt gtggttataa agcgttacgt
     4981 gtgaaagagg atatacagac cgaacggata tataacgaca gcttaaaagc acgagcgttg
     5041 agtttttttc aaaatggttc ggttttaaca gataaaactt tgtttaaatg caaaatggag
     5101 aattatcacg tagtggacca agaaacgaaa attgctttag aaagagctaa aagctatgta
     5161 aatgatgtcc tactgaatca tccttcacat ttcattctat cagggaaatc aggaagcgga
     5221 aaaagccact tatcaatggc gacagcttgg gaaatacttg agcgctcaaa ttatgacaag
     5281 aaaatacttt ttataagcta tcaagagtta ttagagcaaa taaagttttc ttataacaat
     5341 gctgaactga gaaaagaaat tgaaggatcg cttatagccg atatcaaaac aactgatttg
     5401 gtggtttttg acgatattgg agctgaatta ggtagcgggg tatcgaatag taggcagttt
     5461 acaaacaaca cgttaaacac gctcttagaa gccagacaga acaaggcaac gatcatcaca
     5521 acaaacttat ctggtcctga actaagagaa gcctacggcg aaagaattgt ttctaggata
     5581 tttaagaatt cagaaggtta tgcgctgaaa ttccaacaaa cagcagacaa gcgcataaaa
     5641 ccagtgaaag gtagtatcgc atgaataaat accgtaataa aaaaactgtt catcgaggta
     5701 tcaagtttga ttctatcgcg gaagcagagt attacgatct agccttgtgg caagctgaag
     5761 cgaacggctg gaaagtaaaa cttcaggaaa gatttgagct gatgccgaaa tttgaactag
     5821 acggaaagaa gtatcgcaag atcgagtata ttcctgactt cacattttat aaaaacggca
     5881 aacttgtcaa agtcgtagat gtcaaaggaa tgcagacaaa agactttaag atcaaggcaa
     5941 agttgttctg tcatcaatat caagtgccgt tgatattagc caaaaaatat cggaatacgt
     6001 tcaaggaaga gcgtttttaa cgaggtggtc catcatgaca acagaagaag tgattcaaat
     6061 gcgtattcga agcattcaac gtgaaattga cgatctggaa cgaacaaagg cagtgatggt
     6121 caatgaaacg gcaaggaagg caatcgattt acacatagtg aatttaagaa gggaaattcg
     6181 tagattggag gaatgagcgt ggataagaaa gcagcaatga aacgaatcat tgaactgaca
     6241 cattctgaga attggcaaga agacaaagaa atagttgcag aagtccaaaa gctcggtaaa
     6301 tcaatgtgga ctgaaaagcc taaacggaaa acgccgagaa gaattgcaat ctggcatggt
     6361 gaccgaattc tagtaacagg tactgctgaa cagttatctg aaattactgg tctgagcaaa
     6421 aacaccatct gggatagagc tagtagctta tggattgatt caaaaggacg acagtttagg
     6481 tatgtggagg agaaataatg agaacggtca ttcaaggaaa agaaatcaca gtaacaatta
     6541 agtcagaacg agaactagat acacaagaaa taattgcggc acaccaattg gctacaggga
     6601 attttgaggc tttgtttatc aaagaagata gcaaaacatc caacaacaac aaagaagtaa
     6661 aaacgaaatc tgtagaaaaa gatattccga agtgggtcca agtagaaatc acatgccccg
     6721 tatgtactca tgaaagcaga acaacaacta aatacggcaa cgtatttaca aaatgtccga
     6781 gctgtaagac acctttgtat aacaaatatg caacaggaat tgctggtgaa catgataaag
     6841 caggcaacta ctattatgct caggaagttt tacgtcctcg taatggggga ctgactcatg
     6901 aagaacaaga actattaaat gcaatgagcc aggcagtgac tagtgaaaac aatggataaa
     6961 accaatgagt taacaagcaa atatttgggg aaataagaaa tttggaggaa gaaaaatgaa
     7021 cgaaaacaaa ttaatcaaat tgggtgcagc aggagcagta atcgtaggta ttggagttat
     7081 cggaggattt aagttcttcg aaaaaatcga taatggatat gtgggtgtgc gctattcaat
     7141 gaacggcggt atcaaagatg aagcactgac gcaaggtgtg aaatttgtag ggattgacaa
     7201 agtgatccaa tatccaattc gcttgcaaac tatccaatca aaaaatattt cagtatctac
     7261 aagcgacggc aaaaagacaa cgattgatat caaatatgac tacaaagttg attcaactaa
     7321 agcagcaaaa atgtacaagg aatttgggaa tatcacttcg gaagatatcg aaagtggatg
     7381 gttaaaatct aagcttcaaa aggtcgctcg tgaagtttat gcgaaatata gtctgcttga
     7441 tgtcctttca ggagattcct ctaaagttga agctgaggta ttaacgaact ttgctaaatc
     7501 agttgaatct aaagggtttg aagtcgaaga cgtaacactt ggtgttccag atgtcgataa
     7561 agaaacacaa aaatcaatcg atgcgatcat tcgagctggt caagaaaatg aaaaagcgaa
     7621 gctagatgca gaaactgcaa aaactcaagc tgatagtgaa gcttacaaga aaacaaaagc
     7681 tgcagaagca gaggcagaat ctaatcgcaa agtcgccgaa tcagtaacag acaatttgat
     7741 tcgttatgaa gaagctcaag ctcgcaaaaa gcatggatgg gtaacagtaa atggagcaga
     7801 tactgtagtt acggatgaag caggcaaata atatgggatt ctttatggct aaaattctct
     7861 tgttcttagg tttagtagga gcagcatatc tcgtgtatgc gctcctttcc caaactgatg
     7921 acaaagaaga tgacaacaac gatgaaatga aattttagga ggagaaataa tggatctcat
     7981 tacacaatac agtgatatca tcctcaagaa aatcatggca aagattcaga aagataaaaa
     8041 agcaaaagaa cgagcggaat tagttaagtt ggaaatggct gaaacaggag caggagtgcg
     8101 aagtagcagg cattggaagg cagcagcaaa cattgaattt tattacaacg aaattcaaaa
     8161 agggttcgat cagatgcgtg agctggatcg gcaaacaaat tggagcaaga aacttcatca
     8221 agatcgtttt aagtttgtag aaaagtatag agagatactg aatgagtatt tcgaggagga
     8281 ctagatgttt aattcaatgt tagcgtcaat tcacttttta ttctatataa cgatatttgt
     8341 agctatatta attaatacga taaaaagcgg ttttttaaca ccaatcggca caattttaac
     8401 attagcttca tttgttacaa gttgtattat ccaacttaaa tatataaagg agaatgaata
     8461 atggacgaac taatcacaaa agtagagcag tgggctaaag ataagggatt ggatcaagct
     8521 gattccagca agcaaatgtt aaaaacgatc gaagagattg gggaagttgc cgcttctcta
     8581 gctagaaaag atgaacatgg tttaagagac ggaattggag acgtagtagt aaccttgatt
     8641 attttagcta tgcaaaatga tatggatttg tacgagtgtc tgaaccaagc atacaacgaa
     8701 atcaaaggac gcacagggaa aatggtagat ggtgtattcg tgaagtcgag tgatttggag
     8761 gaagcggaat gaacaacaga catcgcagaa taacaaaact aagaaaacag gaactgaatg
     8821 tactaaagac aaagtttgaa aaagaatatg gaatttcagc agaagaaaca tataaagtgg
     8881 caagtcagtg tgttgctgat gcaagtgatg ctattcgtaa gtttggaatt tcgatattaa
     8941 gtgatgatcg taaatgggag gaaaaagaat gaaactaaaa gacggatttt acgctagcag
     9001 tcacggtatc ggcggtttaa tgctagatat gccgacaaag aatcctaaaa cacgtaagaa
     9061 accaaaagtc aaagtcggtg acatggtccg ctgtgaagca gaggagttca tttatccatt
     9121 tcgtggatat gtagaacacg tctataatca ctcagcgatc attcgcattg aaaacacgat
     9181 ggaatgtgat aaatggacag ctaaaagcaa agagaattta gcagtagtga gattggtgga
     9241 tatggaacta atcaatgaca aataaaaaag ccggatcgct ccgactaaca taataaaaca
     9301 gacaagttta ttatatcaca taaaaggagc agtttgactt gatgcaattg ttacgagagg
     9361 tagatttcaa acagacaaga tgtaatgcga gagatgtgct gaagaacttt cggcgtttgg
     9421 agcggatggc aggtcgctct ttgatagata ttaagtcgcc gattattacg gatatgccga
     9481 aggcaccgaa gcacggcaat aaggcagagg atgcattgat tcagatgatg gatatagaag
     9541 cggagagaga cgcgatttta gcggctttga tggctcttag tctgattagt cgtcagatac
     9601 tctactatag cttctgtgac gtaaataagc actctaatta tgaaataggt caattgatac
     9661 gaggatacgg agagaagaat gtagagaagc tgaaatctat cgcgctgatc gaatttgctg
     9721 aagcatacaa aaaaggcgtg ttagttcagt atcgttgatt ttgtagggtt tttgtaggga
     9781 tagtgtaggg tttttgagtg ttttaacgtg atattatgat agtgtcgaaa gattaggaaa
     9841 caggatcgac aaaataaaat gtaagggagg gaatctccct catcgtttta aattaagctt
     9901 cgataggcag caacggaaat attaagaata aggatgtgaa tttcaactcc tcctgattgt
     9961 tcttattatc tatcatccgt tgctgtctat taatttatgt attggagggt aagaatatga
    10021 aattatcgat tgaaggtact tcaggagaaa taaaagagtt gctccaagct attggtggta
    10081 gcaaggagca aaatataaaa attgatgata tttataaaga aagtagagat tttttaatta
    10141 acggtcaagc ttttgctcct agtttttaaa atcttcagaa acagcggaaa gaaattgatt
    10201 ataaagcttt atatattcaa aatatgcatc aaattttgca tctttccctt caattatttg
    10261 agatttaaca atatctctga caaaaggtaa tgttgcaatt gctaaatcat gagcgcgttg
    10321 ttcattggtt aacatagttt tcaccttcgt atatttattt cagcggacca ctcgctgata
    10381 aataaaatta tacacttagt atttattttc acaatattaa tttgtcactg tggcggaggg
    10441 tagacgctta aaataagttc aatacgtcga gggatagcct taacgtttta tgatttgacc
    10501 atgcaatgtt cgattcattg ccagcgattt tagcaactga gggttggaaa tgggcgctca
    10561 aagtacacga gcaaggcgag gtcgatagta atcgatggaa tcggtgtagg ttgctattac
    10621 atattagatc actctttgag tggtcttttt attttacatg aggagtggcg cgagaatgga
    10681 ttcattagat tttttacaaa acaatgtagt gaaagagttg aaagaaaaag gattcgaatt
    10741 agaagatatt caaaagatga ctgttgagga tatagccaac aatttatact atcctaagtt
    10801 ccgccttgaa gtagacagtc agtacggtga atctgtactt tatgcaagcg agaaagttgt
    10861 gagcgaaaag gattcattta tgtacacttt gcctaacggt actctgatta ttactaaacc
    10921 tgcactatca aaatacatcg agcgatttgt tgtagagtct cgtaagcaac acagcgaatt
    10981 tgggaaaccc ttttatataa aaaaacgcaa cgaaccttgg gatcaagacg aagaatgtct
    11041 tgagtatgaa cgaagcatat tgaagaagcg tgatgaaaaa ccgggacctc caataagaaa
    11101 ggactaacac catgagaaac tactggtatg tatcactaac gaataggtat ccacaaccaa
    11161 acgcagatga tccaattaga gttgtccaat cagtccaaat taaaaagaag tattccattg
    11221 ttgaaatgac aagagaagct acaccgaaag agatcgataa gtacaatctt cgttactgcg
    11281 gccatggata ttggaaagac gaatatattc aacaaaacat tgagaggtac atcaaatgaa
    11341 tgataactat gattacatca agttgattga gaagataaga gcagagaaag atatggatga
    11401 actagctacc ttattcatga acatcattag cttggtgggg ttaaagatgg atgaagtagc
    11461 agcactaaat tatttcatcg ctgagcaaac aattagagca gagcacaatg ctaagttctt
    11521 gaaagataga ctagatctag atgtaaaagg attaggcgtt gaagggatat tcaaagtgca
    11581 agaagcctta gtgaatgttt atgtcgaaaa gatgcaatag cattgacaag taattattgg
    11641 atgttttcag gagggaaact atgaaattaa aagattatat tagggaaggg tataacattg
    11701 taactacacc aaatctagct tataaaatcc aagaagatta tcccgatgct ttagtgttta
    11761 ctgatagagc tttagatgcc attcctatag ggaagttatt agttgatcgt tattatagca
    11821 ataatccagc tgttcttagt gctaagccac ttcaaaacgc ttatgctatt gaacgcttta
    11881 cttgcgagtt tactggatat gagacggtag taccaatgac aggtgagaca ggaagaaaag
    11941 taattcaaca gatcaaaaag aggattgctg aattgacgtt agatgatgga agtaatacga
    12001 accttctaga aatcaaacta agagatactg actcagtacc agaagtttat tataaaggtc
    12061 aacgaatgga tgagatgccg ataggtcttg tcgatattac ttatcattgg gatacggaag
    12121 aatatgaatg ccaagtacca aaaggagcta acgacatcac tattgaatat tatgattcac
    12181 ataataacaa gtacttagat agaaaaatca ttgggcacaa gagagatatg taaatgattg
    12241 atgtttcaag taaacaagca agagctaggt tctatggatc aactgagtgg aggaaactta
    12301 gaagtcaatg cttagagcga gatcattatg agtgccaatg gtgtaaagca gagggtagac
    12361 taacaactca acatgattca attcttgaag tggatcatat aaaggagctg gagtatcatc
    12421 cggatttagc tctagatata aacaacctaa gaaccttatg caaagattgc cataacaaaa
    12481 ggcacaaccg tatgaaatat cgtggccaac aaaagaaaag aaagtgggat gatgaatggt
    12541 ggtaagaaaa acagcaaaca gagatgatgt caaacgagca gaagcaatcg ctatggttga
    12601 taaggctatt gataagttgg ttctatttaa gagtcagctc attgaaggaa caacaactgt
    12661 agaggatata tctatcaaca atagactaat aggtaacgct aatgaagtaa cagggacatt
    12721 taatattaat gtagacattg attatacctt gagtccattt gcacatattg tagaaagcaa
    12781 cgagcaagac ggctgataaa tcagtataaa gcgaagatat atagagtgaa atacccccgg
    12841 tcaaaagatt ttgagaagaa ataaaatttt tgggaaccgg tggatggggt caactctgca
    12901 aataaatgat gctattttca cacgaccccc tccccacgta gaaaggaagt gagttgatgg
    12961 ctgatctgca agagagaaat aggcttgttt ctgctgaaga aaggcgtcta aataaattgt
    13021 ttaaggatat tgataaggat aaaaagaagg tcgtttctgg tttgattacg caagcggcac
    13081 gcttaaaaat tcttcttgat gaaatgtgga ttgatatttc cgaaaaaggt gattatgagc
    13141 ttttctctca gtcagaaaat caaaaacctt acgagcggga acgaccagtt gctaaacagt
    13201 ataattcgag agaccaagca tatcaacgtg taattaagca acttactgac tatttgccag
    13261 aagaaaagcg cgaacctaca aaaaatgcag cgctagatgg tagtgatttg ctgtgacaac
    13321 attaaagcca ttctattttg atgaatacgt agatttatac gaaaaagggg taatcccttt
    13381 taataaagaa agaattcagt taattactta tttaaaaaac gaagtgctag ttcgggatga
    13441 tatctatttt gatgaagaaa tgattcaaaa gtttatcaag tacactgaaa aaaatttttt
    13501 tcctttagct aaatatcaaa aatttatcac acctttcatt ttctgctatc aaaaagagga
    13561 cgacgaggtg ttttttgatg aaattctaaa tagtattgcg cgaggcggcg ggaaaaatgg
    13621 gttcatgtca gcaagagact cattttttat tagccctctc tacggtgtca gaaattatga
    13681 tgtaacgatt acagcgaatt ctgagaagca gggaaaggta tcttttaaag aagtttatga
    13741 aatggtacaa atgcgcaaac tggaaaaaca attttatttg actaagatgg ctatagtcaa
    13801 caatgtaact aattcgattt ttagttatag gacaaacaat cctaagacta tggatagtgc
    13861 aagagatggc tgcttagaat ttgatgaaat ccatcagttt gaatcttcag acctagttga
    13921 tattcagcgt agtgggctag ggaaaataaa acatcctcga actttttata atggtacaaa
    13981 tggtcatgtt agagaaggtt tttatgacaa aatgttggaa cgagcacaaa agatttttag
    14041 tggagagaac aagaatgatc gcttgtttcc ctttatttgt aaactggata acattgatga
    14101 aatggataat cctaaaatgt ggtcaaaggc taatccaatg ttcgaagaag attcagcata
    14161 ttcaaaacgt ctgttttcta cagtgatgaa agaatataaa aaactagaag atgagccatc
    14221 aggtaggcgt gaatttgttg ttaaacgaat gaattttaca gaaggtgatg cagaatcaga
    14281 tattacgact catgaaaaat taatggctac taaacaagaa ttgccaaatt tgaatggtcg
    14341 ttcttgtgtg gctggatttg attatgcaag tattcgtgat tttgcaacag tgggtttgct
    14401 ttttaaaatt gatgataaat ttatctggca gcaacatagt tttgctagga aaaagtttct
    14461 agatacattc aaactgaaag cgcctattaa ggattgggag aaaaaaggtt tagtgacaat
    14521 cgttgatgag ccatcaattg atcctcgtca tttaattgat tggttaaatg aaaaaagaaa
    14581 aatccatcaa atagaaatcg tttgtgccga cggatttcgt atggatttgc tgaaacctct
    14641 tctagagaaa gaatcatata attttgagtt tatcagaaat ataagaggtg tgcagtcaaa
    14701 agttgctcct attattgaag atggttttgc aaatgaacgg tttatttttg gtgatgatcc
    14761 tatgatgcgt tggtatacaa ataattcgtt tatcaaagaa gacaaattag ggaataaaac
    14821 atttttgaaa aaagagccag taaggcgtaa aacagatggg tttcatgctt ttttggcagc
    14881 tttatataaa cgagaagaaa taactgatat ggattatgag gaagcatttg atatgttgga
    14941 tgagattgaa ttttaaggta tactccttat tgaaaggggt agttatagaa gtgaaaaaga
    15001 gatattttct atttgttaca atatttataa taatagcaat ttgtgttttg acagtatttt
    15061 taccacaaat tactgagtat ttaaattatc ggatatttac cacaaaagta gatgatagcg
    15121 ttactagttt aagtaggcta gaatttataa aaatatgtgc atctgtgttt ggtcctattt
    15181 tgactgtaat ggtatttgtg aatactttaa atatgcagaa aaaaacagag caaaagcaaa
    15241 atgagcttga agtaaagcaa gctaaggctg agaacgagag agcaaaaaaa gagctgttaa
    15301 cacagataga tcgtgagttc tattttttat taaatatgtt tattgaaata caaaaagatc
    15361 aaaatgccaa acaagctgtt attgctttac agaagttggc aatttttaac gaaaagggtt
    15421 ttaatcaaga ctatgcattt acttctaaag atttatcaga tagtgaaatt gggagtacaa
    15481 ttgaacaatc aggaccgctg aagggcacag ttgaatatat aaaatttgaa acatttgatg
    15541 taagcaagtc gatggggaat tatcaaacaa aaacaaaaga cgttgctaca agtttacacg
    15601 atcagaaagt agctatattg aatgaacaat atgaaaagat gcaaatatat cttggacggt
    15661 acttcaaaat gtttcaccga atagttaaaa cattaaatga gtattatgac gattataatg
    15721 attttgatgt gaagaggtat acaaaatata tagggacatt aagaacacaa atttctccag
    15781 ctgaattcca agtgatttta ttcaattctc tatatataaa acgaggtttt ggcttaggaa
    15841 ttcaacttat tggaagtggt ttttttggag atgattttga ttttgaaact aatcaacatt
    15901 ttgaaacaag tatcaatgaa cagtggtttc tatcactatc aactgttgac agtgataact
    15961 ctataaagcg acaaaaatta tctgaatata ttaaagaatt aggatccgta gaatataaaa
    16021 aaatagctaa ttttgaaagt ttatataaac tctttaatga aactaagctc tagaaatagg
    16081 gcttttttat ttttctttga aaggtggtga aaacatgtga gcttatttga tatctttaag
    16141 cagtcaataa gaaatgaaga gccttctgag tggataccgg attttgtata tggagaggaa
    16201 gtatctgctc gggcatacct caaaattatg gcaaaaaata ctgttttaga ttttgttgca
    16261 agaactatgt caacgttaga agttaagttt aaaaataaag atgggacatc agactgggat
    16321 tatattctaa atgttcgacc taattctgat atgtcagcag ctacattttg gcaaaaattt
    16381 ttttatcggc tcttagatga caacgaagtg ttagtaatat ttacagatga taatcaattg
    16441 ctgattgctg atgattttag tcgaacggag tatgccgtgt atgatgatgt ttttacaaat
    16501 gtgatggtaa aaaattttgt ctttgaacgt tcatggaaca tgtctgacgt catttatatg
    16561 gaatataata acgaagaatt agaaaggttt acacgaggtt tatttgaaga ttacgccgcg
    16621 ttgttcggac ggattctaga agttgcaatg cgtaacaacc aaattcgtgg gtctgtatcc
    16681 attgattcaa cgggaacggc gaatgatgaa aaaggaaaag atggtaagac tagatctcaa
    16741 agattacaag aatatattga taggatttgg aactctttta aaactaactc agttgcaatt
    16801 gttcccaaag tgaaaggctt tgagtatgag gaatacacca ataaacaagg cgtatcgaat
    16861 caatcgctag atgaactgaa taagatgaag tcgtctttaa ttgatgatgt tgccaacgcc
    16921 ataggagtac ctacggcgct tatttatggt gaaaaagctg aactggattc aaatattaaa
    16981 gcttttcgta aattgtgtat tgctccacta gttaaaaaac ttcaagacga attggtggca
    17041 aaaataatta gtcgtcaaga gtacaaaaac ggggaacgta tagaagttaa aaaagttctc
    17101 caaaaagatc tattagagta tgctactcaa attgataaaa taacatctgg tggtgcgttt
    17161 tatattgacg aagttcgtga tgaagttgat tatgatgagt tgccaaataa tgaaggaaaa
    17221 attcgtattc gtacgaaaaa ctatgaagaa actgtgaagg gaggtgagaa cgacaatgcc
    17281 gaaagctaaa aaagtaccat ttcagtttac taacgaaatt cagaatggta agcacattct
    17341 caccttgagt ggaaatgtac agaaaaaata ttggcgtgat gatgatgtca taaacgctaa
    17401 agatattcgt gactctctag atactgtaac cgatgatatt gtaatcaagt tgaacagccc
    17461 aggcggtgat gtgtttgaag ggattgagat ttacaattat ttaaaagatc acccatcaaa
    17521 tattactgta gaagttacag ggcttgccgc aagcgcagca acgtttattg tcgctggtgc
    17581 caatgatgtg attatgaatg ttgggacttc tttgatgatt catgaagctt ctacatttgc
    17641 ttgggggaat aaacaggaca tccaaaaaac gttaaacgca ttggaaacga tcgatgattc
    17701 tatcttagct atttattcag ataagactgg ccaatctgtt gataagttgc gtgaatggat
    17761 gaatgaagaa aaatggttta cagcagatga agctgtcaaa tatggatttg ccaattctgt
    17821 gaagcgtgaa gaaccacaaa atgaacctca aaatattgca gcgatgattc aagatgctgt
    17881 tgccgttgca atagcgaatt taaaggaacc tgttactaat aaaatcgaac aagaatcaaa
    17941 acaaaaatca ttaatcgcac gattgcgaaa aggagaataa agatatgtta aaaattacag
    18001 ataaaactgc agatgcaaaa aaggcattta atgctatttc ttcgaaagaa gatgcaacac
    18061 ccgaacaaat taatgctgct ctagaagaat atgtaaccgc cattgcagaa gatgccggca
    18121 aacaggtgcg tgctgaatat gaagaattga aaaatgtgac ggacaaccgt gtattagagg
    18181 ctcgtggaat tcctacacta acagcagaag aaacaaagtt ttataatgaa gccgtaaaat
    18241 ctggaggttt cgattctgac gtagtttggc cagaaacgat tttggaacgt gtttttgaaa
    18301 atcttcaaaa cgatcatcct attttaggcc tcattaactt tacaccaact gtaggtcgtg
    18361 tcaaagtaat tagagcacgt cgtaaaggtg ttgctgtttt tggaccattg cataaagacc
    18421 ttgaaggcca actagatgct gaatttggtg caactgaatt tgttcaactt gcgttgaccg
    18481 catttttctt aatttctaat gataccttag atttaggacc acgatggatt gaccgtttta
    18541 tcaatctttc tttaagtgaa gcagtacgtg atgtttgggc taaaaaaatt attacaggtt
    18601 ctggtaaaga tgagccaatt ggattgctta aagatctaga tggtgcggtc acaagtggtg
    18661 tatatccaga taaagctagc gcagggacat taacttttgc gaaagagaag attgttcttg
    18721 aacttgcagg ggtgatgaaa aaattatcta aatacacata caaagtagat ggtgacgatg
    18781 aaggtgaagt gaaataccgt tctgttgctg gacgagtgta tctaattgtt aatcctgttg
    18841 attactggga tatcgtagct agagttacat ttgcaaattt aaacaatgtg tatgggacta
    18901 cgatgccatt tatcgctgtt gatcatatca tcgaatctgt agacgtacca gaaagtaaat
    18961 gtattgcata cgttgataaa gagtatgaag ctactcaatc aagagctgaa aaagtctatg
    19021 tatataaaga aacttttgca atgaaacgcg caactttgta tgctgtcgac atgcttggta
    19081 atggctatcc aacaaataat gatgcagcac aagtatatga cttggacttt acagcggggg
    19141 agtaatgtcc cctgcaattg gtgagataac accgacgact gatggggcag tcattaatct
    19201 ttcgtaaatg gggttagagt atgaacactg aagaatttat aaaagaatat aaggcccgat
    19261 ttcgtatttt ccatacttcc gaagatgagg atatcgggaa acagttagag agcgggtttg
    19321 ccgatataaa atctctaatc ggcagttttg atccttccac ttatgagaaa ggaaaagaat
    19381 tagtttatga acgtactcgg tatctacgga acgaatcact agagtacttt tacgacaatt
    19441 ttcaaacaat gattatggat gcatcaattg atctggcagg tgctggatat gccaattaaa
    19501 tcaaattata agaagcctaa aattgtagct ggtgatctaa atacgccagt tacttttttt
    19561 gagtttcaac ctaataaggg tccagaacct ggtgatgaag aaaaaaagga actgtatttt
    19621 tgtacagcac tagtttacaa cccatcaatg aaagatcgtg acattcttgg cacaaaagaa
    19681 ggcgttacga taaaaatacg ggatccccat caatcttata ttcctactaa caaacataaa
    19741 gtaaggatat tagattatcg atatggagat aaagtttggg aaataatcga tgtctcaccg
    19801 gatttggaag aaaattcaat tgtaaagata gtattagaat taattactta aatttggtga
    19861 taaatgatga gtaacgtaaa gtttgaaggc gttcaagaaa caatccaagc tttagaaaaa
    19921 aagtatggag aaaagaaaac taagacatta acaaaaaaag caatcaatgt tggcgctgaa
    19981 aaagtagaaa aacagttgca aacggacatg accgttttta aagacaaagg ttatacgatc
    20041 gctgaggttg ttcgcaagaa cgctacgtat agagattaca aggcagaagc tgaaatcggt
    20101 tggaatggtc cacatcaacg atatagaatc attcatttga atgaatgggg atatacacga
    20161 aagggcaaac aaattagacc gagaggattt ggtgtaataa caaaatctct taagaattcc
    20221 gagctgttgt actttgatgc tgtaggagag gaggttaaaa agagtttatg aaagatatgc
    20281 ttaatatcat ttacgaggct ctttgtttga atgagtatat tcattcaatg acctacaacg
    20341 agaataccga gcaatatcgt attaaatttt atgagcaacc tgaaaccgcc gataaaacag
    20401 gtccaatgat cacaattcgt cctgtagata cacctaacga agcgtaccac ggaagtaaca
    20461 aagagctttc tgtggagcat atgatacaga ttgacgttga atcgaaatat agagcaacat
    20521 gcaagcagat tcaatatgag ataaaaaaag agatgaaaaa actaggcttt ggccaaattt
    20581 ccggtcaagg gttagatgaa tactttactg aaacaaaccg ctttgtagac gcgcgtcgtt
    20641 acgaaggaaa tacaaaaatt tacgataccg aatattagaa attaagacac gaaaataacg
    20701 tgtctttttt tattacccaa aattaggagg aaaattttat gactttagta ggattcaaaa
    20761 aaatgacaat cggggtcttt gacagcacag ggaagattcc agcagcaaat ttatatgtaa
    20821 ttgaaggtga acaaaacaaa ggggcgactg tatctgctga aatcagtggg ctatcaaaag
    20881 aaccatcaaa agtttacgga tcgaacatcg cttactatgt ctctcaaaaa ggaacaggcg
    20941 atgtttcagc tacttttgga ttgttagatt taccaacaga agtaaatgac aaaattcttg
    21001 gttacaaaac cgatacaaac aaaatcagct tcttgggaga agatactgag ccaccatatt
    21061 gtgcaatttt gatggaatcg gaggatttga acggcgatac agcaatgctt gcgatgttca
    21121 aaggaaaatt cagtcgtgaa tctattaatc ttaacactac gacaaatgaa gctttcgaac
    21181 cagaagcaga agaatatgta ttttcagcga ttgccaatga tgttgaaggt gatgctaaag
    21241 gccaaacagt cgcaaaatat gttggagacg aagaagcttc tattactgct ttgaaagaga
    21301 tggtatttcc tgcagcgggg gagtaactag ccccgttgtt ggagcaatca ctcccactat
    21361 taatggggca acagttgaat taagttagga ggataactat gccagataca tttaaaatct
    21421 ataaaaaaaa tggtactgaa tttacaaaag tcgcagaggg tgaaagtcca ctttctatta
    21481 ctggaattgc agcaaatact caagttgcta aaggagatta tcaagctacg cgtgtggtcg
    21541 gaggtcaaga atcagtaaaa gtagatattc ctgcattcac cactcttcca atttcagtta
    21601 ctggtgtgac gttggataaa acgacagctg aagttgaaca aggcggaacc ttaaaattaa
    21661 ctcctactgt aacaccagca aatgcaacag acaaaacagg aagctggagc agttcgaata
    21721 cagctgtagc tacggttact ggaggcaacg ttacagtaaa aacagacgct gaagttggcg
    21781 gaactacaga agtttcattt actactacgg atggcggtaa agtagcaaaa tgtactatta
    21841 cagttattga aaaagcagcg ggctagtctt cggactagct tttttatttg gaaaataatg
    21901 gaggaatcta aatggcaaaa gtaagaattg aattgaaaga agaatcagga aagaaagtct
    21961 atgaaaacat agacacaaca gggaaagatt atcgaaaagc tttagaaaca atcaaaaagc
    22021 taaatgaaga cggagtaatg atttggaatc gtttagacat ttatttggat tttgctgtag
    22081 gtatcttcag ggatagcaaa ttgacagctg aacaaattct tgatggctta ccatctgaga
    22141 aggtaatgag cacattggac gacatcctag gagaagtaat ggggattgaa agtaatccag
    22201 acccagacgc aaaaaagtaa cacccgaaga agcagaagaa atgtacttaa acctatgcag
    22261 agagttagtg aaagcgggat ggtcactatc tgacatagaa gataattcct ttgaaatgat
    22321 gatgaaaatt gcgtgcactt cgcctaagaa agagaaacaa aaagaagttg atcttaaaga
    22381 cttcttgaaa tccatgtaga gaggaggtaa acatatggca aatggaaaac ctttaggcaa
    22441 tatgattatc aaactagact tagacagttc agctttttca aaaggtctag ccggagctaa
    22501 aaacgctgtt aaccatcaaa tgaaagcaat gaaatcacag atgcaagtaa tgaactcttc
    22561 aggaaattct ctcggtgctt tacaagcaaa atacaatggt ttaggcggag ttctacaagc
    22621 aaatgaaaag caagtagaat tgctcactaa ggcttataag gatagttttg actctaacgg
    22681 aaacgctact gcttcgactg ctaaatacgc taatcaattg aatcaagcaa cagctagatc
    22741 agcaagttac gaatctcaga tgaaaacaac tgttggacag attgctcgga tgaaagtgga
    22801 aacggaaggg tttacgggga aactaaaggc taattctgat gtattgatta attctgggaa
    22861 aaaaattgaa gcctttggta aaggagtttc tgggatagga tctgccctaa ctgttggagt
    22921 aacagctcca atagtggcag gcgcaactgc tgttactagt gcagctattt catgggaaag
    22981 tgcttttgca ggtgtaaaaa agacaaatga tgaagttgta gactcgaatg gaaacgtagt
    23041 ttattcctat agcgacttag agaaaggtct gcgtaatctt gccacccaat tacctggtag
    23101 ccatcaagaa atagcaaatg tagccgaagc agccgggcaa ttaggtataa agactgaaaa
    23161 cgtagttagc ttcactaaaa cgatgataga catgggtgaa tcgactaata tgtcggctga
    23221 aactgcggca acttctttag cacgatttgc taatattacc caaatgtctc aaaaagactt
    23281 tgataaatta ggatcagtca ttgttgatct aggtaacaat tttgctacaa ccgaatcaga
    23341 aatcactgaa atgggattgc ggttagcggg agctggtaaa cagattggaa tgagccaagg
    23401 cgaaattcta ggatttgcta ctgctctatc ttctgttggt gtcgaagctg aagcgggtgg
    23461 gtctgccttt tcgaaggtca tgatccagat gcaactagct gtagaaaaag gatttggcgc
    23521 ttttgatcag ctgaaacaga tggcagaaga acaaggtgtt ccgtgggtta atttagtaaa
    23581 tgctgtgaga gacggtggaa aatcgttaaa agcagtatca gagcaaatgg gattcacttc
    23641 atctgattta aagaaaatgt ataaagaagc ggacaattcg aaaagttcgc ttgaaaattt
    23701 tgcgaatgtg gcaggtgtta caagtgaaca attccagaag ttgttcaaga gtgatccttc
    23761 agaagcaatc atcaagttca ttcaagggct gaaagattca gaaaaacatg gtacttcagc
    23821 aatcaaagtt ctggatgaca tggatataaa agaagttcga ctacgcgaca gtttattgag
    23881 agctgcaaat gctagtgaca tattcaaagg agcaattgaa aaaggaaacg gcgcgtggaa
    23941 acaaaataca gctttaacaa atgaagctaa taaaagatac gaaacaactg aatcaaagct
    24001 aaagatattg aaaaacgaag tgattgatac agcaatcgat cttggaggtc catttgtaga
    24061 cgcgttgcgt gatggtctaa atgtatcgaa accattgata aaaaacttag ggaatatggc
    24121 gaaagctttc tcagctatga gtgatgatca acaaagaaac attatcaaat gggttggatt
    24181 agcagcagca gctggtccag cgctgaagct tttaggaact ggtacttcag taataggtaa
    24241 agttacttca actactggaa gattgacgaa aagccttgtt gatttagcag cgaaagcagc
    24301 agaaaagaag gctatggatg cctttgcatc gtcggtaaca acagctggtg ctgcagctgc
    24361 aaagacagca ggagctggag gtattggcgg gttagtccct atgatgggaa aaacagctag
    24421 tgctgcaagt actgctgcgg gcgccagcgg aataggcgca atgacaacgt cactaggttt
    24481 gttaggtcct gctctacttg gtattgttgg cgttggtggc gcactggcag ttggctatgg
    24541 agcatggaaa ttatttggtg aagaagcttg gaattcctcg caaagagtaa agcaatgggg
    24601 aacagatgtc ggtgaggaga tagatagtac tcttgacgga gtacagaaga atattgaagg
    24661 tgcaaatggt caattcggtc ttctcaaaga gggttttact gttgatgatg caaataatat
    24721 ggcggctaat ttcgcaaccg ctggaacatc tttggaaaca tctttaacgg gtagaataaa
    24781 ggcattagac gatgcactaa aagggctacc tcaatcagtt caggatgcca tgaaagaagt
    24841 agctgaatca gaagaagaaa ccttagggca atctctttct aaaataaaag acaacaatga
    24901 agaaataaaa aaaatcagag aaagagccgc aaatcagaac agagacttga ctgtttcaga
    24961 actacaacag atacaggatc taatgaaagg aacttctcaa gcgtatgtgg atacgctcga
    25021 tgtttctgct aaagacagaa aaaagatact atcagccatg aatggtgatg ttgcacaagc
    25081 tacagaagaa gaagcgaaga cgtggttaca atctttagcg aaacaaaaag ctgcaactac
    25141 cgaaaattat agacaaatgc ttgaagaaaa aaaggcggct ttaaaggaaa agggagtaag
    25201 caaagaattc attgatgcat tagaagatga aatgaatgat tacatcaaaa ctacaaatca
    25261 aggattcgat agccaaatag ctgctataac aaataaatat ccacaattga ttaacgaagt
    25321 gagtttatca aatggtcaat tatttagcaa aacggcagct gctatggaca atactggtca
    25381 gtatacaaaa gtttttctcg aaagtaatga aaagatttta gcccaagcga agaaaacatc
    25441 ggatgaaata gcagataatg ccgaaaaaaa tgcagaacaa cttggtatgg tagctgatga
    25501 ggctacgcat gctggatcaa cttggaatgg cttagtttta gacgaaaaaa caggaaaagt
    25561 aaaaactaat gtacaagaag tagtgaatga agcaacgaag gatttcacta aatggaatga
    25621 attgaaacct gttgttcatg atgcgaaact aacaacgaat gcaaaagatg tcatttccat
    25681 agcggcagta caaaatggct attgggatga tatggaatgg aaagaaaaag aagcattatt
    25741 agaagatgag tgttctaaaa atgtatacaa ggctttagaa aatgctggta aatggaatga
    25801 gttagatatt ccttctaaag aagcaatcct aacttcaaat actcctgaag ttatgggtga
    25861 aactctcatg aatttgggat tatgggatac ttacaaactt caagtgaaag atttagattt
    25921 gaatgcgtat aaagtatacg atgctatcga tggatcagaa gaaaaattaa atagttgggc
    25981 tcaattagat aaccccacaa aagaattgtt attagataac tcagattttt ctacaaaact
    26041 ttttaattcc gaagaaatgt ttaaacgttg gaatcagtta tcatctaatg caaagtttct
    26101 ttcggctaat aatactaaat ttacagaggt tcttttatca tctgacagaa tgtggaatca
    26161 atgggtaaac cttcctgata atgagaaaag attacttgca gataacgaag atttagctac
    26221 cactgtttta tcttcagaag aaatatacgg aagatggact caattaccag ataatcaaaa
    26281 atatatgtta gctgacaata ctgacttagc aaacaaaata ttcgcttcag aagaatcatg
    26341 gaatgcatgg aaagcaattc cagacacagt taaaaacttg cttggtaata atattgattt
    26401 actggctaaa gtgaaagacg ggactgtaag tgtagaagaa tataacaaag ttatgccact
    26461 tcttaaaact ctatatggag ataacgttaa tttaaaagag gcaatcagtg gggctaaaag
    26521 ctctatagag aattacaaca aaaatatttt tcctagtgat aaaactgcag taggacacga
    26581 tgaggcttca caagctgcta aagatgcatt tgaagcgttc aacatcttcc aaacaaaaat
    26641 accagataaa attactaaaa ctgtatcagc tgactttata ggtcctatgc cgaaaaatgc
    26701 gaaaggaaca aacttccatc ctggcggagc agctatggta aacgatcaaa aagggcctac
    26761 ttatgaagag cttataacct tgccaagcgg agaaactttt atacctaaag gacgtaatgt
    26821 cgttttagac ttaccaagag gttcgaaagt actgaacgcc actaaaacta aacgtctagt
    26881 gcctaaatat gctgatggta taggaaacat aacgacggtt tcatctacgc taaacttaga
    26941 tgctttaatt ttagctatta acgagctaac gacggtattg agaactcaac tgatggcagg
    27001 aacgactgat gctaaagata ctaaactatc agatgaaaca aaagttgccg atccgattat
    27061 tccggacagt ctttctgaaa aatcagatca gtatctagga attggagctc aatggttaac
    27121 taatctaatg aatggttgga actcagcggt tcctcaatat atgaatagtg aaatggtttt
    27181 tattacaaac tatctcaatg cgctaaaact tcaaaacaat cctaattata cgcaaggagc
    27241 aacatggaat aagaacttac tgaatggatg gaatagttta actgggacct ttattgctac
    27301 aatcaattca ttttgtaatc aagcaatggt cacgcttaga aactacaaca ctcctatgta
    27361 caacaatggc cgaacgtggc agcaaaataa tcttaatggt tggaattcat tgtatggatc
    27421 attcatagcc cgtgtaaatc agcttggtaa cgattcgatt aacaaccttc gttctaaaag
    27481 tggtggtttt tacaatgcag ggacattctt gttgcaatct ttaataaacg gaatgaattc
    27541 gttaggtaat tctctttcta ctacaatgaa caatgtcgct aatacaatgg ttggtggtat
    27601 aggcaaagga gttaatggcg tcatatcggg agttaactat gtgcttaagg aagtcgaatc
    27661 aagtaagaat atcggaaact ggccaattcc acaatacgct aagggaactg atggacatcc
    27721 tggtggactt gctatgatta atgatcaaaa aggcctagtt cacgaagaat atgttcagat
    27781 gccagatgga cgtagtttta ttgccaaagg tagagatctt cttgttaatt tgcctaaagg
    27841 tgctcaggtc ttaaatgctt ctttaacaaa gaaattaaag gaacgtttaa atattccaca
    27901 ctacgaaaaa ggtattggca atttagatat tgttgatttg ttagatgatg aaaaaagaat
    27961 gttagaattc ttaactagca aagttgattt ttcaggcatt aatgaaccat ggcttgatat
    28021 gactaaatca ggaacgtcat taatgtccaa agctgcaaat acaatgcttc aatcaaaatt
    28081 aagtgaattc ttcactcatg gcaattttga tggtgcagta aatgccaatg gtgtttatca
    28141 atatttagtt gatgtggcac agaaagtaat gggtaagttc cccggactta cagtaacttc
    28201 tggatatcga gcaggagatg cctactatca cggaaaacgg caagctatcg acttggctta
    28261 tccaggtatt tctggagatc cgagatatac agcagcagca aattacgctt ttgaaaaatt
    28321 cccttcaaaa attgcgtatg tcattacgaa tggacgtgta cgtgaccgca tgggattatc
    28381 tggaacaagg tcaagcggac aatggacgaa ttggccagat ggcgatcact tcgatcatat
    28441 tcatttaaac ggttcgatgg ggtctggcga tatattcaat ggaggagttg gaggaagtgg
    28501 tgttgcacgc tggcgttctt atgtgtctaa agcattgaaa atgaatggat taccagctac
    28561 agcagcgtat ataaatgcct ggatgtccca aatccaaacg gaatctggtg gtaatgagaa
    28621 agcaatcggc ggcaatgatg ggctcgccga aggcaatgca acaggattac ttcaaacgaa
    28681 acccggaact tttgcagcta acgcttttcc tggtcacgga aatattatga acggatttga
    28741 taacatgtta gcagcaatca attatgctaa gaaacgttac ggagttgcag gtatgttgca
    28801 agttatcggg aaaggacatg gatatgccaa tggcggcttg attaccaaag acggactata
    28861 tcgagcagga gaaggaaata aaccagaaat ggttattcca ttgacaagaa aaacaagagc
    28921 tatcgaactt atgggtcaag cattagcctt cctttctgga agcaataaaa aagaaacgaa
    28981 aagtgagatt aattctgtag ataatagaca tatcctacaa gcgatagaaa aacagtctcg
    29041 tatgacaaat gatctgctat cattattact ctcgtttttt aaaagtaaca atcgatcaga
    29101 taaagaacta gctttagata ttcagaaaat tttaatcagg aggacatagt atttgaggac
    29161 agtaatatta agaaataaat tgaatgaaga aattgatttg tccacagaag attattttgc
    29221 tactgaaatg tcgaatctag gttttgaagt tacaaaagag catattggac aatgggggag
    29281 tttcagagaa ataggagaga gtattgaatt gtctgaattt caatcatcag ttatgatttc
    29341 tgttcacgga tttagagaac aacaattata tggttcatta gttgaatttc tggctaatgg
    29401 accttttgaa ctagaatttt cttttgattc agaaacaatg atcaggaaat gtagtttgaa
    29461 atcattatct aaaacagaaa ttgattccca aagctcattg ctaacagata ctttgaatct
    29521 atattttact tcaagctggt attctattaa gcgtgaaaaa ttaatacaga attcaacttc
    29581 tctcaataca cgtggaaaag tttactcatt tgttcgacca tatgtctaca ccaaaaatgt
    29641 atgggaaaag aaaggtgtat ttaagttcag taataattct gtatatttga caaatagtac
    29701 agagcgaatg tctccgttaa aaataaggat tattggagag tgctcaaatc catattggga
    29761 agttatccaa aactctaaag tagtagcttc agatggctat tttattaata tgaaagacac
    29821 acaaatatta gaagtgtcta gtttgctaga agaccaaacg gcaattttaa aagatgtagg
    29881 tggagttgaa tcttctgttt atcaacaaca agattttact aaatcaaact tcgtccaagc
    29941 gcctctagga gaattcagcg ttgtttttca tgttggacat gcaaatgtag agattgaact
    30001 ttatgaggag cgtgatctat tttgatttta gccattaccc tctttcaccg agatatgaat
    30061 ttatataacg aacgtttaat ttcgactgag ttcgaatttg gaacggatga aattggagaa
    30121 gaagtaagta attttattac agataaatat gtccatgtaa aatcaggaga ttttctacta
    30181 gcaaaattta ttcctagcgg gaagattgct tattttggag tgattagctc gcaagaagac
    30241 aaaaaaataa attgcaaagg attactcagt ttggccgata gcgagatacc gactgtaaaa
    30301 atatcaggtg ctaattatga agagcatatt cgacgactga ttgaatacta cttattgaac
    30361 gatccaacaa aacaactaaa aaatattttg gaggtaaaaa cagaaagcgt tacttctcat
    30421 tcttatcaag ctgttgacac aaataagaga cgattgaatg catatataat aaatgggttc
    30481 aaaaaatata atgttaaatg gtatgtcaaa gagattaaag gtaaaaaaat atatactggt
    30541 attcgagcag ttgatgattc aatttatatt aaagataatt catctgagtt taatgactgg
    30601 gatgtttttg tgcaatctcc tggaccaggg aacgagaaca aattattgat cgtagataaa
    30661 gcaatgaaag atatagaaaa tcccttggta ttgtctacgt ggtatttaga tgacgaaaat
    30721 aatcttacgc aagattcaac gaataagaac attgcattgc ctaccgttaa tttagtaaat
    30781 atatatgatc aaactcaaga agatagacct tcttatgaag aggtagctaa atcggagctt
    30841 aaaggcaacg cctattcaca tgaaattaaa gttaatgttg tgctaaatgc tagaaatatc
    30901 aatgtagaaa atatcgaaac aggaatgtta gcgactattg tttacaaaga gcagacttac
    30961 aaatctgttc taactgcctg gcgaatatcc agcagtaaaa agaatataga attgacattt
    31021 ggtaatgtcc gaagtcgttt tatggattat tttgaagata atgggggata aaaaatggtt
    31081 agcaatgtgg atggatatca atttgaaaac gtgaaagtaa gcgcagaaaa tgatgctaga
    31141 ctttatcacg ttttatataa tcggaaaaat caggttattg atggttacga tcagtctatg
    31201 aatttatctt caagcggatt aacagtaaaa gttggtgcag gagcagcgat tattcaaggt
    31261 cgtatggtcg ttgttcgaca agaagaaagt ataacagttc cagcaaactc aagtggttat
    31321 atagcattaa cagtggattt gacacaagaa gttatacctg gatctattct tccagaatcg
    31381 gaagaatatg aatggactaa taatcaagtc aagctagaat ttataacaaa agttatagaa
    31441 ggtaatttaa acaatggtga taaggtctat aatttaccac tatgctcagt tacttctact
    31501 ggatcaactg tttcaatctc aaagatatcg gatagttacg agctgactct ctctaaagga
    31561 gaaattttgt ggagggggac tgcgttaatg catgatactc aaactgtcca accttcaaaa
    31621 aaaatttggc agacagtttc aggtttttta ttagtatggc tcccctacga aaacgggcaa
    31681 gcaattgagg atagatatgt aactacacct ttttataagg aacgtgtaac tgttactaat
    31741 gttttaggag aaattgtttc aggatttgat gactatcaca aaaagtggtt tagtaaacga
    31801 ataaactata attcgaatac taatatattt acaggtgcag caagcaatgc aagtggagat
    31861 aacgcaaata tggtgcttag gtatatagtt tctttttagt taggaggtat ggaaaagtgg
    31921 caaatttaga aattaaatta tctgcaaata agagacagcc ttatctacgt caccgtgttg
    31981 ttggtagagt tggtgatggg gggctcacaa caatcaatgt acaacttctt gaggaagatg
    32041 aaattacacc ttttgtaatt aatctaaacg gtactttgaa atttgtgggc gaagtttcaa
    32101 acggtaacta taccgaggga gaaccagaaa taatcgattc gactaatggg ttaattagtt
    32161 acacgttcac taagtcaaat ttcagcacga gtcatcaatt caaacaagca tattttgaat
    32221 atgtagatcc taacggcaaa aaagtaactt ttcagaactt catcatagac gtgttagaac
    32281 gagtggatat taattcggag caagcgaaat actatatttc ttcattggaa aaattacaga
    32341 gtgaaatgca aaccactttc aatcagttca ttagtgataa acaggtccaa tacgatcaaa
    32401 tctactcgaa atataacgaa ttagtaagat tgataaatga atcagataag caagcgaatg
    32461 atcgtattga taaggcaaat gatcgtattg atcaaaccaa tcagcaaatc ggcgatctcg
    32521 gcaagctgaa aaagatgtac agtaacagca tcgacttcgg ggactatgat tatagtggga
    32581 atccgaattt aatagccaat ataaacgctg acagcttctc gcaaggtatt ggtgctttat
    32641 ctgttattga tgatggtgac gaggtagtgg tcacgcttga tccaaaccat aaattagaag
    32701 tattcaaagc gaaaagtcaa ccagccctgt taataggcaa aacatatacc ttgagtgtag
    32761 agattatgtt agaagatgat ttcactggag accctagtac gataggccta agatatatta
    32821 aaatgcctaa ctgggcatca gaactatata cgcgtaatgc attaactact gctaagggtg
    32881 tatggcaaaa actaactggc accgttaaaa ttactgctac gagtgataac gctgaaagct
    32941 ggcttataat gctacaaaat aaagacgcta ataacagcct atctggtaga ctacgtttga
    33001 gacacgctaa acttgaagaa ggctcaacag ccacatcata tcagcctaac ttactcgatg
    33061 cgccgtatta tttgagtaat aagcctttgg gtgagaatat tgctaatcct acagttaaat
    33121 tcccaatcac gctgagtaac gaggcactct atgcaaaaaa tgcatcagag gattttgttt
    33181 taggtgaaac ttatactgtg acgataaaag caactaagcc tgtctcacaa acgattaggg
    33241 tttatttaac tcaaaaacaa ttcggtgagt ttaaaccagt tgaaggattg gttgatacat
    33301 gggtcgccac tgtgtcaata aaacagctag gggagaacac aaaatgggta tacctttctc
    33361 aaacgccaaa tacttcttta ggtcctgtta aaattgactg gctcaaaatt gaaaaaggcg
    33421 acacacgaac cccaaatatt agtgaatata aatactttgg tgaaggattg aaagatagca
    33481 acaatccgaa cgactacagc tgggacatca cgcctgaata tactgaaaaa ggcttgaatg
    33541 atacggttag tttgactgaa ccgcaatcca tcgaaggatt gaaaaatttc gaagatggta
    33601 ttcaatcaaa aggaaaatct gtattgacat cagacgacaa caaatatgaa gtcgtaacct
    33661 taacagttac aaacgggaat accggatcag caaagcttta tcgtgaagga aaaaccgtca
    33721 ctatttattt ttttgcgttg aatgggaaaa gcagtggtgg aaatgattca acgatactaa
    33781 caattccaga aggctatcgg ccaccaatta gttttgagca actggttggc tcgatagacc
    33841 gttctacttt gaacagtgct cagttatcta ttggtgcaga tggagccatt aaatggcgaa
    33901 gaaactcaag ttatggatcg gattatacct ttgcaattac ttacacgatt tagaaaggcg
    33961 tgaatcgata tgaaggcagc atatagacca attgaacctt acggattcga gcaaatcatt
    34021 gtgaatgatg aagaacattt accggaagaa tgcacagaag tcgaaccacc gattccaaat
    34081 tggaaaccga aattcaatta ctgggaggga aataaatgaa aaacatttgg aaatatggac
    34141 gtactggcgg agagtacgca ggaaaagtat tggacgacat gcttgtatcc gttccttaca
    34201 cagatcagcc accgcttgaa gggattcgtg ctgatggcga accgctaacg attgctgatc
    34261 agatgtttga tcctaaactg aaccaatgga ttgttttagc gaacacactg gatcacaacg
    34321 atttaaacaa tctcaaagcg atgtatgagg ctctggaaca tgaaaacgac aacctaaaac
    34381 agctaaatgc caaactcatg ctaaacgatg tagcaattaa acaggaaaat actgcattga
    34441 aagaaaaagc ggatagttta gcacaaatca attcaaagac aatgcttgct tcgcttcaaa
    34501 acagcaagga tattgcagaa attaaaaagc aattaaatcc agaatcagaa ggaggtgagt
    34561 agtatgttta gttttagcga tgtgaaaatg atgtttgact ggagctgttt tacagaagaa
    34621 caggttcgtg agtttgtgcc attgtgtatt acagacgaag aagcagataa aatcattagc
    34681 aaagaagaga gcgcatctta attgatgtgc tttttaattt gattcaagga gttgtcacat
    34741 gattaattta ggggaatggg gaacaatcgc aggatcaatc actgcgattg tttctttgat
    34801 tttattagta ataaaaccaa ttactgcatc tttctcgaag attactgaga ctctttcaaa
    34861 agtaagtcac aatttagatt tgctgactaa agatttagaa tctagcaaat cagatcgatt
    34921 gatgattcat gaagaactaa agaaacacga tgaaagatta gatacacatg cagaaaaatt
    34981 ggt
//
LOCUS       DAZKPE010000024        34950 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000024 DAZKPE010000000
VERSION     DAZKPE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.024"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..815
                     /locus_tag="ACG930_001297"
     CDS             3..815
                     /locus_tag="ACG930_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFQ0518467.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="ACG930_001298"
     CDS             812..1612
                     /locus_tag="ACG930_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFQ0518468.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="ACG930_001299"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="ACG930_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFQ0518469.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="ACG930_001300"
     CDS             3109..4818
                     /locus_tag="ACG930_001300"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFQ0518470.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5030..9382
                     /locus_tag="ACG930_001301"
     CDS             5030..9382
                     /locus_tag="ACG930_001301"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFQ0518471.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9526..9999
                     /gene="rimP"
                     /locus_tag="ACG930_001302"
     CDS             9526..9999
                     /gene="rimP"
                     /locus_tag="ACG930_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFQ0518472.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10023..11198
                     /gene="nusA"
                     /locus_tag="ACG930_001303"
     CDS             10023..11198
                     /gene="nusA"
                     /locus_tag="ACG930_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFQ0518473.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNSKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11220..11513
                     /locus_tag="ACG930_001304"
     CDS             11220..11513
                     /locus_tag="ACG930_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFQ0518474.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11510..11821
                     /locus_tag="ACG930_001305"
     CDS             11510..11821
                     /locus_tag="ACG930_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFQ0518475.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11834..14140
                     /gene="infB"
                     /locus_tag="ACG930_001306"
     CDS             11834..14140
                     /gene="infB"
                     /locus_tag="ACG930_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFQ0518476.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14167..14514
                     /gene="rbfA"
                     /locus_tag="ACG930_001307"
     CDS             14167..14514
                     /gene="rbfA"
                     /locus_tag="ACG930_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFQ0518477.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14622..15126)
                     /locus_tag="ACG930_001308"
                     /pseudo
     CDS             complement(14622..15126)
                     /locus_tag="ACG930_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15291..17654
                     /locus_tag="ACG930_001309"
     CDS             15291..17654
                     /locus_tag="ACG930_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFQ0518478.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKLGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRNDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFHSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAKKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            18022..18945
                     /gene="truB"
                     /locus_tag="ACG930_001310"
     CDS             18022..18945
                     /gene="truB"
                     /locus_tag="ACG930_001310"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFQ0518479.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18949..19890
                     /gene="ribF"
                     /locus_tag="ACG930_001311"
     CDS             18949..19890
                     /gene="ribF"
                     /locus_tag="ACG930_001311"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFQ0518480.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20242..21027
                     /locus_tag="ACG930_001312"
     CDS             20242..21027
                     /locus_tag="ACG930_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0518481.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21040..21891
                     /locus_tag="ACG930_001313"
     CDS             21040..21891
                     /locus_tag="ACG930_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFQ0518482.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(22015..22467)
                     /locus_tag="ACG930_001314"
     CDS             complement(22015..22467)
                     /locus_tag="ACG930_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518483.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(22932..23300)
                     /locus_tag="ACG930_001315"
     CDS             complement(22932..23300)
                     /locus_tag="ACG930_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFQ0518484.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            23450..23932
                     /locus_tag="ACG930_001316"
     CDS             23450..23932
                     /locus_tag="ACG930_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFQ0518485.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            23969..24979
                     /locus_tag="ACG930_001317"
     CDS             23969..24979
                     /locus_tag="ACG930_001317"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFQ0518486.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(25094..25807)
                     /locus_tag="ACG930_001318"
     CDS             complement(25094..25807)
                     /locus_tag="ACG930_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518487.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(25980..26587)
                     /locus_tag="ACG930_001319"
                     /pseudo
     CDS             complement(25980..26587)
                     /locus_tag="ACG930_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            27071..27298
                     /locus_tag="ACG930_001320"
     CDS             27071..27298
                     /locus_tag="ACG930_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFQ0518488.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            27314..28480
                     /gene="hemW"
                     /locus_tag="ACG930_001321"
     CDS             27314..28480
                     /gene="hemW"
                     /locus_tag="ACG930_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFQ0518489.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            28714..29757
                     /gene="hrcA"
                     /locus_tag="ACG930_001322"
     CDS             28714..29757
                     /gene="hrcA"
                     /locus_tag="ACG930_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFQ0518490.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            29851..30414
                     /gene="grpE"
                     /locus_tag="ACG930_001323"
     CDS             29851..30414
                     /gene="grpE"
                     /locus_tag="ACG930_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFQ0518491.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            30465..32294
                     /gene="dnaK"
                     /locus_tag="ACG930_001324"
     CDS             30465..32294
                     /gene="dnaK"
                     /locus_tag="ACG930_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFQ0518492.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            32445..33611
                     /gene="dnaJ"
                     /locus_tag="ACG930_001325"
     CDS             32445..33611
                     /gene="dnaJ"
                     /locus_tag="ACG930_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFQ0518493.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(33693..34322)
                     /locus_tag="ACG930_001326"
     CDS             complement(33693..34322)
                     /locus_tag="ACG930_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518494.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            34334..34507
                     /locus_tag="ACG930_001327"
     CDS             34334..34507
                     /locus_tag="ACG930_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518495.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(34735..34941)
                     /locus_tag="ACG930_001328"
     CDS             complement(34735..34941)
                     /locus_tag="ACG930_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518496.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
BASE COUNT        11853 a         6036 c         7500 g         9561 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagt agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtgatca cagcagctgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcggtagtag gagtttacga gctgttccgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtatcgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactattcaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt ccgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcacga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcgtgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 caggtaaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcata ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta taccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg atcatcggag acggcggcgc aatgggcggg
     3721 aaagactcaa aggaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgtggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tgctttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaacg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat attcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaattgg
     4501 ccaaaaggaa ttgcgccatt tgatctgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaagcc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg cgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctacattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgtgtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cagctaggac gaaatattcc
     5701 agccgatgaa ccaacgacac caatgatcag tatcgttgaa gaagaacgaa gagtcacact
     5761 tgaggggtac gtattcgaca aagaagtcag agaactacgt tcaaaacgca agatcttgac
     5821 tttgaaaatc acagattata cttcatcatt tatcgtcaaa aaattctcga acggcgaaaa
     5881 agatgaacaa gtatttgatg cgatcagtgt cggtagctgg ttaaaggtac gaggaagtat
     5941 tcaagaagat acgtttgtcc gtgatttggt catgaatgcg caagatatca tagaagtcaa
     6001 acatacacct cgcaaagatt atgctcctga aggggaaaaa cgagtagagc ttcatgttca
     6061 tagcaatatg agtacgatgg atgcaacaaa cagcatctct gatcttgtgg cacaagcagg
     6121 aaaatgggga caccgagcta tcgccattac agaccatggt ggtgcgcaag cctttccgga
     6181 agcacatagt gctggaaaaa aagcaggtgt gaaaatctta tacggcgtgg aagcgaatgt
     6241 cgtagatgat ggtgtcccaa ttgcttataa tgatgcacat gaagcattga gtgaagccac
     6301 atacgtcgta tttgacgtgg aaacgacagg attgtctgca gtatatgaca cgatcatcga
     6361 gctagccgca gtcaaaatgt ataaaggaaa tgtgatcgaa agctttgatg aatttatcga
     6421 tccaggacat ccattgtcac gaacaacggt agatctgact ggtatcacgg atgaaatggt
     6481 tcgagggtca aagtcggaag aagaagtatt gcggatgttc cttgaatttt caaaagatac
     6541 aattttggta gcccacaacg cggcttttga tatggggttc ttgaatacta gctacgcaag
     6601 gtatggtatt cctgaagcgg ccaatccagt cattgatacg ttggaattag ctagatatct
     6661 gtatcctcaa ttcaaacgtt tcggattagg tgtgttatct aaaaagtttg gtgttagctt
     6721 ggaacagcat caccgagcaa tctatgatgc tgaagcaact ggtcacttag catggatctt
     6781 tgtgaaagag gcaatggaca atcataacat gctttatcat gatcagctaa atgagcatat
     6841 cggagaagga gattcttaca aaagggctcg acctttccat gtaacgattt tagcaaaaaa
     6901 tcaggcagga ctgaaagatt tgttcaaact gatttcaatg tcgaatgtcg aatacttcga
     6961 acgcgtccca cgaataccac gctcccaatt gaaaaagatg cgtgaaaatc tattgatcgg
     7021 ctcagcttgt gataagggag aaatattcga agccatgatg caaaaagggg tagaagaggc
     7081 aagaaaccga gcaaaattct atgattatat tgaagttatg ccaaaagcgg tctatgcgcc
     7141 tttgatcgag caagaattgg taaaaaatga acatgatttg gaagaaatta tccaaaattt
     7201 ggtagaaatc ggaaaaagtt tggataaaat cgttgttgca acaggtaatg tacattatct
     7261 gaacgaagaa gatgccattt accgaaaaat tttgatcaat tctatgggcg gagcgaatcc
     7321 gttgaatcgt catagtttgc cggatgtcca tttccgaaca accgatgaga tgctaactgc
     7381 atttcacttt ttaggggaag aaacagcgaa agagatcgta gtagaaaata cgaataaaat
     7441 cgcagatatc tgcgaagaag tgattccagt caaagatgaa ctttatacac cgaagattcc
     7501 aggttcagaa gatgaaatat cagaattgag ttacacaaaa gcaaaacaaa tgtacggaga
     7561 tccgttacct gagatcattc aaaaacgatt agaaaaagag ttgaattcta ttaatggtaa
     7621 tggcttctcg gttatttatc tgatcgccca aaaactagtg cataaaagta atgaagatgg
     7681 ctatctagta ggttcacgtg gctctgttgg ctctagcttt gttgcgacga tgacaggaat
     7741 cactgaagtt aatccattag cccctcatta ttattgtcca gagtgccaat attccgagtt
     7801 ttttgaagat ggtacgtatg gttctggatt tgacatgcca gaaaaacaat gtccaaaatg
     7861 tggtgcacgc ttaaacaaag acggtcatga tattccattt gagacatttt taggattcca
     7921 tggagacaaa gtgcccgata ttgatttgaa cttctcaggt gattatcaag cagaagccca
     7981 taactatacg aaagtattgt ttggcgaaga ctatgtttac cgtgccggaa cgattggtac
     8041 agtcgccgac aaaacagcat atggctatgt aaaaggatac gaaagggaca ataatctgca
     8101 gtttcgaagt gcagaagtcg acagattagc aaaaggcgct actggagtca aacggacaac
     8161 cggccagcat ccagggggga tcatcgttat tcccgattat atggatgtct atgattttac
     8221 gccgatccaa tatccagcag acgatcaaaa ttcagaatgg aaaacgactc attttgattt
     8281 ccactcgatt cacgataatg tattgaaatt agatattcta gggcatgatg acccaactgt
     8341 tattcggatg cttcaagatt tatcagggat cgacccacaa acgatcccta cggatgaccc
     8401 ggaagtgatg cggatatttg ccggtcctga agtacttgga gtaagtcagg aacaaattta
     8461 ttccaaaaca gggacattag gtattccaga attcggcact cgttttgttc gagggatgtt
     8521 agaagaaacg catcctacaa cttttgcaga actactgcaa atttccggac tatctcatgg
     8581 tacagacgta tggttaggaa atgcggaaga attgattcga cgaggagatg cgacactggc
     8641 ggaagtaatc ggctgtcgtg atgatattat ggtttatttg atccatgctg gattagatag
     8701 cgggatggca tttaaaatca tggaaactgt tcgtaaagga caatggaaca agatccctga
     8761 tgaattgcga gaaacctatc tatcggcgat gaaagaaaat aatgtgcccg actggtatat
     8821 cgattcttgt tcaaaaatca aatatatgtt tccgaaagcc catgctgcag cttacgtatt
     8881 gatggctctt cgtgtcgctt atttcaaggt ttatttccct attttgtatt actgtgcata
     8941 cttttctgta cgtgcagacg actttgatct agtctccatg tgcaaaggaa aagatgctgt
     9001 gaaacaagca atgaaagaaa tcacggacaa gggattagat gcttccgtaa aagaaaagaa
     9061 tcaactgaca gtgctggagt tagccaatga aatgctggaa cgaggattca aatttggaat
     9121 gattgatttg tataaatcgg atgccgttaa ctttgttatt gaaggtgata cgttgatcgc
     9181 accatttaga gctgtcccaa gtttgggaac caacgtggcg aaacaaatcg ttgaagcaag
     9241 aaaagacggt ccatttttat ccaaagaaga tcttgccacc cgcggtaaag tttcaaaaac
     9301 attgatcgaa tatatgaacg acaatggcgt attgaaagat ctaccagatg aaaatcaatt
     9361 atcgttattc gatatgctat aagcatctgt tttcctgtct gcttgtaatt ttaagcagag
     9421 tatggtatag ttcttatagg taatgatact aactgtgagt gagcggattt ttcgctcact
     9481 ctttttaatg gaattacgca cttaattttt aaggaggcga aacttttgag tagcgtcgtt
     9541 gaaacagtca cagaaatggt gacaccgatt ttagatgaac aaaattttga acttgtcgaa
     9601 gtcgaatttg taaaagaagg aaaaagctgg ttcttacgag tatttattga caaagaaggc
     9661 ggtatcgata tcgaagaatg cgcctttgtc agtgagaaac tgagtgaaaa acttgatgca
     9721 gcagatccag atccgattcc tcaagcttat ttcctggagg tatcctcccc gggagcagag
     9781 cggccattga aaaaagaaag cgactatgaa aaggcacttg gtgattatgt ccatgtctcc
     9841 ttataccaac cagtagatgg cgaaaaacaa tatgaaggat ttcttcaatc atttgatgct
     9901 gaacagctta cattgaaaat acgcataaaa acacgagaaa aagaattgac ttttgaccga
     9961 aaaaatattg caaaagctcg cttagctatc caattttaat cacggagagg aatcagaaaa
    10021 aaatgagtaa agaaatgtta aatgcgttag acgctttaga agctgaaaaa gggatctcaa
    10081 aagaaatcgt gatcgatgca ttagaagcag cattggtttc tgcatacaaa cgtcactatg
    10141 gccaagcaca aaacgtcgaa gtggaatttg atcagaaaaa aggaaagatc catgtctatg
    10201 cggtaaaaga agtaacggaa gaagtgatgg attcacagtt ggaagtctca ttgaaagatg
    10261 cacttttaat caatccagca tatgagatcg gtgatacgat ccgttttgaa gtaacaccaa
    10321 aagattttgg acggatcgct gcgcaaacgg ctaaacaagt tattttacag cgtgtacgtg
    10381 aagcagaaag aacgattatt tataacgaat tcagtgctta tgaaaaagac atcatgcaag
    10441 gaatcgtcga acgccaggat aaacgttata tttatgtcaa tcttggtaaa attgaggcag
    10501 ttctttctaa acaagatcaa atgccaaatg aattttatca accacatgat cgaatcaaag
    10561 tttatgtttc ccgagtagaa aatacgtcta aaggtccgca agtatttgtt agccgcagcc
    10621 atccagacct attgcgtcgc ttatttgaac aagaagtacc agaagtctat gatggaatcg
    10681 ttgaaattgt cagcatcgcc cgtgaagctg gcgatcgttc aaaagtggca gttcgctcaa
    10741 atgatccaaa tatcgatgca gtcggtacat gtgtcgggcc aaagggacaa cgagttcaag
    10801 caatcgtcaa tgaattaaaa ggcgaaaaca tggatatcgt cgaatggaat gaagatccag
    10861 ctgtattcat cgcaaatgca ttgaatcctg cacaagtcat ggatgtgatc ttcgatgaga
    10921 caaattcaaa ggcctgcaca gttgtcgttc cagactacca attatcgcta gcaatcggta
    10981 aacgcggaca aaatgcacgt ttagctgcta aattgactaa ccataaaatc gatatcaaat
    11041 cagaatctga catgacggaa ttttatgaaa atcaagaaca acaaaaagaa acagaagaac
    11101 tgcatgatga agcaatcgtt cagtcagatt taacagacga tgaatatgaa acaattgcat
    11161 tcaacaatga aacggtcgaa gaaaaaccag aagcttaact ttagtaagga ggcaaagaga
    11221 tgaaacaaag gaaaattcct ttacgcaaat ccgtggtttc aggtgaaatg aaacctaaaa
    11281 aagagatggt ccgaatcacc cgttcaaaag aaggggaagt atcgatcgat ccaactggaa
    11341 aaatgcctgg acgaggagcg tatgtctcac ttgagccgga agaagtacaa caagcttggg
    11401 ataaaaaaat tctcgatcga gtactcgaaa caacattaac agatgagttt tatcaagaac
    11461 ttcttgacta tgtcactcac caaaaagcac gtaaagagtt atttggaaaa tgaatacagt
    11521 taatcggcaa aaagccatga atctcatcgg tctagcgatg cgcgcgggaa aactaatcac
    11581 gggtgaagaa ctgaccattg ctgaaatccg caaacaaaaa gcaaaattgg tgtttgtggc
    11641 aaccgatgca agtgagaata caagaaaaaa gataaaagat aagagttcat attatgaagt
    11701 tccttgcttt gagctatttt ctgaagcaga aatcacgcag atgatcggaa aacctcgcaa
    11761 ggtattcgga ataatggatg ccggatttgc gaagaagacc aaggagctaa ttgaaggtta
    11821 ggaaggtgat tgcatgggca acaaaagaat ctatgaatta gcaaaagaac tcaaaaaatc
    11881 tagtaaagac gtcgtggaaa aagcacaaca acttggcatc gatgtgaaaa accatatggg
    11941 tgcgattact agcagtgatg agaagaaatt gcaacaagcg ttcaaaaacc caagcacgaa
    12001 acaacaagct gcacaacaag caagcagaaa accagccaat caacagccga acgatcaacg
    12061 taaaaaagaa acaacgaaca atcaacaaaa aaataaaaat aaccgcagtt atcaagatcg
    12121 cggtcaaggg agcggtcaag tgaatcaagg aaaaaaacca acaacaaacc aaaataatac
    12181 gggaaatacc agcagccaaa atcgtcaagg aacgagccaa ggcggcaatc aaaaccgtac
    12241 taacaataac aacaaaccaa acaataacaa tcgcggcaaa tttaataata ataaccgtaa
    12301 tcgttataat aaaaaaggta aaaaaggcaa acagcaacaa tcaactaaac cagctgtacc
    12361 accacgcaaa ttccgtgaat tgccagatgt attagagtat actgaaggta tgaacgtagc
    12421 agatattgcg aaaaaaattc atcgtgagcc agcagaaatc attaaaaaat tatttatgct
    12481 tggtgtcatg gtcaatcaaa accaagcact ggataaagat acgattgaac tgttagcgac
    12541 ggactatggc atggaaccac aagaaaaagt ccaagttgac attgctgata tcgataaatt
    12601 cttcgaggca gaagaagtcg atccagataa attagtctca cgtccgccag tagtaacgat
    12661 tatgggacac gtagaccacg ggaaaacaac cttattggat acattgcgcc attcacgtgt
    12721 aacaagcggc gaagccggcg gaatcacaca gcatatcggt gcctaccaga tcgatattga
    12781 tggtaaacca atcactttct tggatacacc aggacatgcg gcctttacaa gtatgcgtgc
    12841 acgtggagca agtatcacag atatcacgat cttagttgtt gctgcagatg atggcgtcat
    12901 gccacaaaca gttgaagcaa tcaaccatgc caaagctgca ggcgttccaa tcatcgtcgc
    12961 tgtaaataaa attgataaac caggtgcaaa tcctcagcat gttatgcaag aattaagtga
    13021 gtatgaatta attcctgaag catggggtgg agaaacgatt tttgttgaga tctcagcgaa
    13081 attcggccaa aacatcgaag aattgctgga aatgatcctg ttagtcgcag aagtagaaga
    13141 tttaaaagca gatccaacac aacgcgcaat cggaacagtg atcgaagcac gtcttgataa
    13201 aggtaaaggt cctgtgtcaa ccttacttgt ccaagaagga acacttcacg ttggtgaccc
    13261 aatcgttgtc ggtaatactt acggacgtgt ccgtgtaatg acaaacgatc ttggccgtcg
    13321 cgataaagaa gcaggacctg caacgccagt agaaatcact ggcttgaatg atgtacctca
    13381 agcaggtgac cgtttcgtag tcttcgaaga cgaaaagaca gcacgtgcag cgggtgaaga
    13441 acgcgcaaaa cgtgcattat tggaaaaccg tgctgccaca agccgtgtga ctttggacaa
    13501 cttatttgaa agcctgaaag aaggcgaatt gaaagaagtt aacgtaatca tcaaagcaga
    13561 tgtacaaggt tcagcagaag cactggctgc atcattgaag aagattgatg tggaaggtgt
    13621 ccgtgtaaaa atcgtccatt cagctgtcgg agcaatcaat gaaagtgatg taaccttagc
    13681 agcagccagc aacgctatta tcatcggttt caacgttcgt cctacaccgc aggcaaaagt
    13741 gcaagctgat actgaagaag tcgatattcg tcttcaccgt atcatctata aagccatcga
    13801 agaaatcgaa actgcgatga aagggatgct agaccctgaa tttgaagaaa aaatcaccgg
    13861 tcaaatgatc gttcgtgaaa ccttcaaagt ttctaaagtt ggtacgattg caggtgccta
    13921 tgtaacagaa ggatatattc gtagagatag cggtgtccgt gtaatccgtg acggaatcgt
    13981 aatctatgaa ggccaacttg caagtctgaa acgattcaaa gatgacgtga aagaagtcaa
    14041 aatgggttat gaatgtggtg cgatgattga aaaattcaat gacatcaaag tagatgacgt
    14101 aattgaagga tttatcatgg aagaagtcaa aaatgactaa aaactgataa aaggaggcca
    14161 atcattatgg ctaactaccg tgatcgccga gtcggtcaag aaatcttaaa agaagtcaat
    14221 gatattttgc gcaaaaaggt ccgtgaccct cgtgtggaga acgtaacgat cacagatgtg
    14281 aaagttacgg gggacttaca gcaagcaacg atctattaca gcattttatc tgacttagca
    14341 tcagataaga aaaaagcaca agatggattg aataaagcat caggattgat tcgtcgagag
    14401 ttagggcaca atctaagtat ttataagaca cctgaattgt tctttgaact tgatgaatca
    14461 gttgtctatg ggaaccatat cgatgaattg cttcgcgact tgaacaaaga ctaatcaaaa
    14521 aatcccgcaa atcctgtgaa atcaggggtt gcgggatttt tttgttttca ttaagacgta
    14581 ttacctaaga gttccatgac tttagtctgg tagcgtgtca gctaaccaaa aaagagaaaa
    14641 agaaaagtaa aaaattcgac tttctttttt ctatagtata taaatttttg catatagata
    14701 aagatcaaga taccgataac ggaagctaga ttgtaatcta ttttagtgac agtcaggtat
    14761 agccaagtaa ctagaagatc agtggaacct gcaccataaa agtttgagtt tgtcggtccg
    14821 ttgacagtta aaagaaaaat cacgttgaag ttattgatat ttccgattac gccgcttcga
    14881 tttggtcacg atccaaattt tggataatcc ctgtagaaat tagcatagta gctgggatac
    14941 caattcacat attgacaaag ataacagaga cttttacata aaacggatca atcaggaaag
    15001 gaattgctcg atccagcccc agttttccaa caatgtgtta actggcctag cgtcattcag
    15061 caaattatgc atgatgagga gcgaaatgaa ctgcggaaca gccattgtga taacgacaag
    15121 ttttttggat caatgtaaaa aacgtcagcg aaaggaaaaa tttcgtggtt ttttatacct
    15181 gttcatttgg ctagatataa aatccaaaca aatgaacaga agtgcttatt aggtttcaat
    15241 tgggagtatc tgcgctagaa taagagtaat aatgaaaagg agtgttatgt atggattatt
    15301 ctagtaaaga atactttgat aaaatgacgg cttggtggcg tgctgctaat tatctttctg
    15361 ttgggcaact ttatcttaaa gataacccct tactgagacg tacactgaaa ccagaagatg
    15421 tcaaaaaaca tccaatcggt cattggggaa cgattcctgg ccaaaatttt atttatgtcc
    15481 atttgaaccg agtcatcaat aaatatgatt tgaacatgtt ttatatcgaa gggccaggac
    15541 acggcggaca agtcatggta tcgaatgctt atttagatgg aagttacaca gagatctatc
    15601 cagaagtaac ggaagatgag acaggaatgc aaaaattatt caagcgattt tcatttcctg
    15661 gaggcattgc ttctcatgca gcaccagaaa caccaggttc tatccatgaa ggcggagagc
    15721 ttggatactc tctttcacat gcagtcggag ctgtattaga caatcctgaa gtaatctctg
    15781 ctgtcgtgat tggtgatggt gaagcagaaa ccggtccttt agctggaagc tggttctcaa
    15841 atgtctttat caatccagtg atagatggag ctgttttacc gatccttcat ttaaatggtg
    15901 caaaaatagc caacccaacg atcttggcac gtaaatcaga tggagaatta gcaaattact
    15961 ttaacggact tggctgggag cctttcttta ttgaaggaaa tgatccagaa aaattaaatc
    16021 ctgttatggc tgaaaaaatg gatcaagcaa tcgagaaaat caaatccatc caaaaagaag
    16081 ctcgcctgaa gacagcaaca gatgtcgtga tgccaaaatg gccagtattg atcgtacgca
    16141 caccaaaagg atggaccggt ccaaaagaat gggacgggga accaattgaa ggaaccttcc
    16201 gagcacacca agtaccgatt cctgtagatc aagaacatat ggatcatgca gatgctttac
    16261 tccgttggct gaaatcctat gaaccagaaa aattatttga tgcacaagga cgtattttag
    16321 aagaaatcag agaaattgcg cctactggtg accaaagaat ggcaaaaaat cctatcacca
    16381 atggtggaat cgatccaaga ccgcttatta tgccagattg gaaaaaatat actttgcaat
    16441 ttgaaaaact aggctccgtt aaagcagaag atatgaccga acttggtaaa ttcgttcgcg
    16501 agatcattga gaaaaatcca gaaaatttcc gtatatttgg accagatgaa acaaaatcaa
    16561 accgattgaa tcaagttttc aaaacgacaa atcgccaatg gatggaaaaa atcgaaccag
    16621 aaaatgatga atggctttcg ccatctggtc gcgtcatcga cagtcaatta tcggaacacc
    16681 aagatgaagg gttcttagaa gggtacgttc tgactggacg gcatggtttt tttgcaagtt
    16741 acgaatcatt cttgcgagtg gttgactcta tgttgactca gcacttcaaa tggatacgga
    16801 aatcacatga cctttcttgg cgaaatgatt atccttcgct aaatctcatt gcaagctcaa
    16861 cagtcttcca gcaagatcac aatggatata gccaccaaga tccaggaata ttgacacatt
    16921 tggcagaaaa gaaggcggag ttcatccgtg aatatctgcc tgcggatgca aatacattgc
    16981 tcgcagtcat ggataaagca ttccactcgt cagaaaaaat caatttgatc atctcttcca
    17041 aacatccgcg tgctcaattt tactcagcag aagaagcagc cgtcttagtg aatgaaggct
    17101 tgaaaatcat tgattgggct tcgacagcaa aagaggagga acctgaattg gtcattgctg
    17161 ctgcaggaac ggaatctaac ttagaagcat tagcagctgt aactttgctg ctggaagaat
    17221 tcccaaaact aaaaattcgg ttcatcaatg tcgtagattt attgaaatta cgtcatccaa
    17281 gtcaagatcc gcgtgggttg agcgatgaag aatttgatca atattttaca aaagacaaac
    17341 cgatcttatt tgctttccac ggttatgaaa cattggtccg cacgattttc tttgatcgtc
    17401 ataaccatca tttaatgatt catggctaca aagaaaatgg agatatcacg acaccatttg
    17461 acatgcgtgt agtaaatgaa cttgatcgtt atcatttggc aaaagacgca gctttaaaaa
    17521 tcaaaggaag tcaagcagaa gattttgcga aaaaaatgga tcagaaatta caagaacatc
    17581 aaaactatat tcgtgaaaat ggtattgatc tgccagaagt attggattgg aaatggaaaa
    17641 atcttgacca ataaaatgat aaaatcgatc ccgcaaaata gaatttttta cattgattaa
    17701 gaaactgaaa aaataaataa aaaaaacgga aaaaagactg gaagaatggc cagtcttttt
    17761 tttcgttttt gggaagtgaa aaccaaacta tttacctgta agccacccat aaatccaatc
    17821 aaatggtgca aagaaaaaat cttccattct attccctcct ttaaaaaagc ataacatgat
    17881 ttctatttac gtgagcatga attttgttac gtttttattg ccgaaaaata aaaaccgttc
    17941 attatgatgt caaattcgtc agtaattgat gcaatgtgtt ataataattc agttaaatca
    18001 aaaatgaaat ggagaaaaga catggacggg ttattacctt tatggaaaga acgcggaatg
    18061 acaagtcatg attgcgtatt caaattaaga aaaatcttac atacgaaaaa aatcggacat
    18121 gggggtacgc ttgacccaga cgtagacggt gtgttgccca tttgtattgg aaaagccaca
    18181 aaagttatcg aatatttgac agattctggg aaaatctatg taggcgagat aactctaggt
    18241 ttcagtacaa cgacggaaga tcgatccgga gaacgggtag aaacaaaacc agtagatatg
    18301 tctttatctg aaaaaaaaat agatgaagtg atggcttcat ttattggtga gatcacccag
    18361 ataccaccaa tgtactcagc ggtaaaagtc aacggtaagc ggttatatga atatgcccgc
    18421 aataatgaaa cagtggagcg tcctgttaga aaggctcaga tttaccgttt tatccggaca
    18481 agtgaattga caagagacga agtgacagga accatttctt ggcgcttcga agtagaatgc
    18541 gggaaaggaa cctatgtccg cacattagct gtagatacag gcaagaaact tggttaccct
    18601 gcgcacatgt ctgatctgac ccgaacagca agtgccggta tgtcccagaa ggatgctctg
    18661 acattagaag aagtagctca agctgtgaaa aatgggacaa tcgatgattg tttgctgcca
    18721 atagaaaaag gagtggaacg gttcaaacga gtagatatta ctgatgaagt atggcagaaa
    18781 gtaaaaaacg gtatgagact tgattatact gtatttgcgc tcccagaaat gccgtcagaa
    18841 gaaattgctt tgttttataa aggaaaagtt gtcagtattt atcagccaaa cccgaaagaa
    18901 aaaaacaaat taaaacctag taaagtattg agaaatgagg aataacgaat gaatatcatc
    18961 aagatcagac atccttacca atcagaacaa attccagaag acgatgtcgt tttagtgctg
    19021 ggatttttcg acggcgtgca tatcggacac cagaaagtca taaagacagg tatggaaatt
    19081 gcacaaaaag aaggattgaa attagcattg atgactttca atcagcatcc atctattgtc
    19141 tttaaaaaga tcgatcctag cagcgtgaaa tatttgacta gccttaagca aaaagaagaa
    19201 aaaatggccg ctttgggtat agattattta tatgaagttg attttacttc ttcttttgct
    19261 catttagcac cgcaggaatt tgttgatcaa tacatcgtag ggttacatgc aaaatatgct
    19321 gtttccggtt ttgattatac gtatggacca aaagacattg cagatgtcgc tcattttcct
    19381 gaatatgcca aaggaagatt caaaatcgtc acagtttcta aagaagaaga acaaggtgaa
    19441 aaaatcagct ctacccgtat tcgtggatta ctagacagcg gacaagtaaa agaagcagca
    19501 aaactattag gttgcacata tgaggtagaa ggggtagttg tccatggcga tgcacgaggc
    19561 agactactag gattccctac agcaaatgtc aaagtaaaga gcacggttca tttgcctaaa
    19621 gaaggtgttt atgtgtcgga aataaaaatt ggggaaacat ggtatccagc catgggttca
    19681 attggacata atgatacatt cggtgaagga cgggagctga ctgtagagtt gtatattttg
    19741 gactttaatc aagatatcta tggtgaacat gtcgcggtac gctggaatca atttttaaga
    19801 gatcaagtga aattttctag tgtagaggaa ttgattgaac aactcaagga ggatgaacaa
    19861 gcaacagctg aatatttttc tcagcaataa aacattatgc ataaaatctc ttgtttatgt
    19921 ataactagca attacaataa aatgggtgat aaataagccc aggaaagggg ctgtgacaaa
    19981 agtcttgtca cagccttttt ttccaaataa atggtttttc agaagtagct tcttcggaaa
    20041 taagccgaaa tttcttgaag ctgaccactt ctgtcacaac ctctttcttt atagaaataa
    20101 aaggacacta gcaattcatg aaaacgattg ctagagcgta tcatttgctt tagactatat
    20161 atcttggtgt acactcactt taaggcggaa ataaaagtta tccgtaataa caggtttagg
    20221 tatgaaaaag gagtgggtac tatgtacaag gaattagaaa acaaagtcgc agtagtaact
    20281 ggtggctcaa aggggattgg aacagcgatt gctcaacgat tcgggaaaga aaaaatgaat
    20341 gtagttgtca actataactc ggataaagaa ggagcagaaa aagcagtcaa agcaatcgaa
    20401 gaggcaggcg gaaaagcagt ctctgtacaa gcagatgtca gttctgaaga aggaatacag
    20461 cgtttacttg atacggcttt agaaaatttt gggacactgg acgtttgggt taataatgct
    20521 gggatggaaa atcagcatcc aacccatgaa cttagccttg aagattggga aagagtgtta
    20581 aaagtcaatt tgactggcgt ttttatcgga acgaaagcgg ctttaaatta ctttacagag
    20641 aataataaaa aaggaaatat catcaatatg tcttctgttc atgaacagat cccatggcca
    20701 acgtttgctc attacgctgc ttcaaaaggc ggggtaaaat tatttaccga aacggtagca
    20761 atggagtatg caccgaaggg aatcagaatc aatagtatag gccctggtgc tatccgtaca
    20821 cctattaatg cggcaaaatt tgatgatcct gaacaaaaag aactcttgga aagtatgatc
    20881 ccactaggac gcgtaggtga accaaaagaa atagcggcga cagctgcatg gttggcttca
    20941 gacgaatcca gttatgttac aggtattaca ctatttgcag atggtgggat gactttatat
    21001 ccttctttcc aaggtggaaa aggataaggg tgaataaaaa tgggtttatt gattgcattg
    21061 atcccggcag ttggctgggg gatccagcca ctgattttga aaaagattgg tggcagacca
    21121 acaaatgaga tattaggaac tggtattgga gcggtgcttg tcggcttact cgttcaatta
    21181 ttcgcttctc cagctggtat ttcagtgact acatttttga ttagtttact ttctggtgca
    21241 ttttgggtta ttggacaaac aggacagtat acatctttca acttgattgg tgtttctaaa
    21301 acgatgccaa tttcgactgc attacagtta gtcggaacct cgttgattgg tgtcttcgct
    21361 tttggagaat ggtctggaag tatggggaaa atcattggag cagcagcaat cattcttctt
    21421 gtatttggtt ctgctttaac ggcaatcagt gatgatcctg gaaaaaaagg cggtatcaca
    21481 aaaggaatta gtctattagc atcaacaagt attggttatt gggtatacag tgcattgcct
    21541 aaactagttg atgcaagcgg actttccatt ttctttccgc aaatgatcgg tgtcttttta
    21601 ggggcagtga tttatgtgat tttccgtaaa ccaaccgcat tttctgaaga caagagttgg
    21661 aaagcaacga tcgttggagc catctttagt gtgtcagcat tggcttatat tttttcagca
    21721 aatgaaaatg gggttgctac tgcatatatc attacacagc taaacgtagt tatctctaca
    21781 ttaggcggta tgtacatcct gcatgaaaat aagacaccaa aagaaaaaaa attaacgatt
    21841 atcggattat tgctgatcgt agtaggaagc atggtcacgg tctttatttg aggataaaga
    21901 tggtaaaatt tcatttatta aaaaaatatt tgtttgaacc aaacagtaag tacttataaa
    21961 aaaatagcgc tagaatttcc aacatctctg gaatttctag cgctttttaa ttgtttaaga
    22021 tacaagggaa atatctgtct ggatcaataa tttttcattg atccattgac taaagtttac
    22081 gacataattg aagttaccac cgattagtat ctccgcatga ttgtctttat aaagatcgta
    22141 ttgtaaaaga cggtcttttt tatttgcgta aacatcgtta tggtactgga ctaattgttc
    22201 tcggaattga ttgattgctg taaaatcacg atattgaagg ttgaaacgca tcgtgattgg
    22261 tgcatttagc atgaatcgct gcatttcttt tgctgcttcc tctgcttgat ctccgtatag
    22321 gaactcaaaa agattacgtt cagaaaattt ccattgcccg ccaacctttg ttccttttag
    22381 ttttccttca tgaagataat ttctgataga acgtgtagta acacctaatt gttcggctaa
    22441 ttcatttact gagtaaaaat ctttcaatgt tcaccctcct atgtgaatgg ttctactgac
    22501 ttagttgata tttgcttaat cacgaaatgt agaaagaacg attttaatta aggtcattgt
    22561 aaaaatcaag tcagaaaatt ctaactttta tttctctaaa gaaattcgtt ctctcctaaa
    22621 gtgatattat atttaaatat acctgaaaat aatgggcagt attatgaaag atcactgata
    22681 ttttctcgta ttttttcctt attcaaaagt tttgcaggaa aattgctgaa aaaataattt
    22741 tactaagtag aaaattcaaa gccattcaat cagtgatttt tttcagcaca agaaagactc
    22801 cttataaaaa tagcagatac tttgtcaatt aagtgtttaa ccagggatga taaaaaggat
    22861 aggattgaac aaaacctgta taaggtgatg aatagtttcc tcgccagtaa aaggtttatt
    22921 cgtataaagc tttatcgcca aaatttatca tgaccttttt tatcttcaat attaaatgaa
    22981 atcaattgtt caatcaattc ccagttgatt acacttttcc aaggaacttt gatgacgtta
    23041 tccgtatata cgtagcctgc ttcttggata tttttttcaa gggcacgaat cgctgctttt
    23101 tccggtgcga tagaaaaatg atttttagca aaactaaatg caataataaa ggtaccatgg
    23161 tcagtaaaca taggttggtt ccattttaca gttgtgtcta gctggggata cgtttctgtt
    23221 atcttagcaa aaaggtcttt gatcttttgt tgatgttctt tttctttgat ttgattgatg
    23281 atcggctgaa atttttccat tctaaaacgc ctccattaag tggtttgatt tattttacca
    23341 gaaaaacaat agttatgtat aaaaaacgaa caaaacacaa gtaatgttgt aaccgctata
    23401 tttatatgat aagatgtctc aaataataaa atagaaaaga gacataaaaa tgattgactt
    23461 ggcaaagaaa ttcttacacg aaaatatata ttttgagttg tatcatcatc gagccattta
    23521 tacaaatgaa gatgctttgg taataaagaa agaacaagga tttacaggta cagagaccaa
    23581 aagcttattc ttaaaagata aaaaagataa taactacgta tatctgactt ttactacgaa
    23641 acaaacggat ttcaaagcat tagggaagat cgtcggtaaa aggctttcta ttgtttcatc
    23701 agaacgcatg gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt ttggttatga
    23761 aaaacagatt ccgattatta ttgatgaaga gctcttatca aatgaaaaac ttgtttttgc
    23821 accaggtaga ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca aaatcatcca
    23881 gctacttgag atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt aaccaagtaa
    23941 aatagtgcat acttggaggt gaagcaacat gataagttat ccattattag aaagaaatgc
    24001 aacgattggg gttactgcac catcctcagg cgtatcagag gaacaccatt cgttactcga
    24061 atcagcttta aagagaatgg aagaaaaatc tttccaagta gttactggaa agacgctttg
    24121 gacgcaagat aaggaaaaat caggtccagc aagaaaacga gcagatgaat tcaatcaaat
    24181 gatgcaagat gaaaatatcc aaatgatctt tccgacttgg ggaggagaat tattgattga
    24241 gattctcgat tttgtcgatt ttgatgctct acaaccaaaa tggatagtag gttattcaga
    24301 tattagtacg ttgctacttg ctgtcacatt aaaaacaggg atagccactg cacatggaac
    24361 taaccttatt gatttaagag gagagtactt ggatgaaacg acagcaatgt gggaaagtgt
    24421 actgaaaaca agagaaggag aatcgattct acagcaatct tctgaaaagt atcaaaaagt
    24481 gtggccccat gagcattcat catcttctgt tttccatctc actgaaccaa caaattggca
    24541 atcagtcagc ggagatgcag taaggatgaa gggacgatta ttaggtggtt gtattgatac
    24601 gatcaggcat ttaatcggta ctccttatgg agatgtccaa tcttttaaaa gaaagtataa
    24661 tgatggaaag ccgatcttgt ggtttctaga aaactgtgag ctatcgtcag ttgatttaag
    24721 aagatcactt gttcagatga aactggcagg ctggtttgat ggcagctcgg ggatcatgtt
    24781 cggtagaagt gcggcagagg atttgttaga ttataaaatg aaggatgtat acgaagatct
    24841 gtcaaaggaa ttaaaactac cgatcttgta tgatattgat tgtggtcatg taccgccaca
    24901 actgacattg attaatggtg cctatgcaga agtagcggta gaagatagaa aagcgactgt
    24961 tttgcaaacg tttatttaaa aaattttttc ctgccttgga gtctatcaaa gaccaataaa
    25021 tctaaataga aaagaaagtg aaagaagctg acaaaatgct gtcagcttct ttttgtataa
    25081 catattagaa agtctaatta tctataactg tcacatcgat taactgtttc acgtcattgg
    25141 gatttcctgt aggaatagct actacagatg cattatcaat gatttcttga gttgtttctc
    25201 taatgaacgc tggataagat gtttgatctg caggcatttg ccaatgtgaa ggaactggat
    25261 aactagtgat tgtcccgtca tggttacttg aatacactaa aactccctgg taactgtatt
    25321 tcccagtgag cataaccaca tctttcggat agactgcact ccctgcatca taaggggcga
    25381 taggtgttcc tgcaggataa tgaataacat gtaattcgaa atcacccgat gtatctctaa
    25441 aagtattacc tctaatagct agccaaacac gtgcgtactc aatttgtaga tcagaatatc
    25501 ctgctaacgg atctattgac tgagaagact gtgaggaggt tgtgtctatt gttgaagaag
    25561 aaatatttgt ctcaactgta ctactagatg tagaagaagt attgggctct gagactttac
    25621 tgcttgttga agatgtattc gtttcagtag aagctgattt ctgagtactt gatttttcag
    25681 ctgaactggt ttgtctgatt gaacttttgt ctgtggtcgc agatggatca ctattttctt
    25741 tactaggaga cgtacatcct acaaggaata aagagaccaa caataaaata aaacctaact
    25801 ttttcatata aaatacctca ttattttttt aataccagta tagcataatc ctgaattttt
    25861 gaatccgtaa aaccttgtct atgaatataa atagagtgta tcttctttga taaatgtcag
    25921 aaaaagtgtg acaaataatc atcagtaaaa ttacttgtca cactattgat aaggagtatt
    25981 taattgaaga gaatgattag gagaaaggat ctccgtactt tttatagtaa tcatagaatc
    26041 caagtttgta tagacgaatc gttttttctc ttatttcttc tgtttcaaaa tggactgctt
    26101 gaagaatcaa gtctgtgaat tctataggag ctgttccatt cgcagtaatc aaattacgat
    26161 ctttcacagc ttgttgttct ataaaatctt ctttattctg ataattttcc gattctaacc
    26221 aaggaaattg cgcatttccg gtgtgtttgt aaccttgcaa taatccgctc tgagctaaat
    26281 aatcaactgc cccacaaata gcagctactg gtacgtctgt ttttaacaat ttatcgatta
    26341 tttgatataa atgatgattt tttatgtccc atgaattgcc accgatcata ataaaaaggt
    26401 caactttttc aggtatttgt tcgattaagt aatcgatttt tgtttttaat cctccaatgg
    26461 aagtgacctc tgattggata gaagcagttt tgttttgcca tttctcattt tggtttagtg
    26521 tgctagtaat ataagcacct tcccaatcgg catattcctc taatagaaac gtaatcgcag
    26581 ttttcatttt caagctctcc tttactatct ataacaagga caacagtttt aacctacaga
    26641 cattcattaa aattgggtag cgacagcgaa aacaacaatt cttaagtttt agacagagta
    26701 tacagatagt caacttaatt aaatacgaac taaataaaaa tgacaggtaa tcatttttgt
    26761 ttaccagcat tataacattt tgcatacatg gatgacaaaa gaaccaattc ccacttgctt
    26821 gagtacaata ttaaaagaaa ctggaaggca aaaagtaatt atagaaacga aaaataaatc
    26881 atatcgggca ctcagacatg aaaacaaccc tagagatata taactaggta accagtttaa
    26941 tgaaagaaaa aatcatccaa gaagtcgatt cttggatttt ttagtggatt tgttcgccaa
    27001 atacgtttag tatgcgtata tgagaggttg taagcaaagc gttgtggtct gagcacttaa
    27061 ggaggaatct gtgaaaatag cttttcatat ttttgcagat tttgacttaa tgccgaaggt
    27121 cagctttgcg attaccgttt atcgagaggc tgtaaaagca ccgtgtagct ccgatgacaa
    27181 taagcaagca tttttagagc taggtttcct tgattctaaa tatgcggctt atttcaatga
    27241 gttggtgctt gaacgcgatt ttaagaaggt cgaaaacagg cacgactttt cgacgtaagg
    27301 agaaagaatt tcaatgatag aaacaataaa tcccgcagaa aacaaggttt ctgcgtacat
    27361 tcatatccca ttttgcgagc atatctgcta ttactgtgat tttaataaag tttttttaga
    27421 agggcagcca gtagatgagt atgtggaaat gctgctgaat gaaatgaaaa taatgctaga
    27481 aagtcatccg acagcgaatt tagaaacact ttacgtaggg ggcgggacac caacttcttt
    27541 atctgctaaa caacttgatc gactgttatc aggtgctaga gagatcctgc cttttcaaaa
    27601 tggtaatgag tttactgtag aagcgaatcc aggtgatttg acccgtgaaa aacttcaagt
    27661 aatgaaaaac tatggcgtca atcgtttatc catgggagtg cagacatttg ataatcgctt
    27721 attgaaaaaa attggacgta aacacaccgc agaagatgtg tatcaaacta tgcaattttt
    27781 agaagcagaa aattttacca atgtaagcat cgatttgatt tatgcattac cgggacaaac
    27841 actagaagga tatctggata ctttggaaaa agctttggct ttggatctgc ctcactattc
    27901 tttgtactca ttgatcctcg aaaacaaaac aatgttcatg aactgggtac gacaaggaag
    27961 actcgaactg cctgatcagg aaacggaaac cagaatgttt gaagagacga ttgaagcaat
    28021 ggaaaagcat ggacgtcacc aatatgaaat aagtaacttt gggctctccg gacatgaatc
    28081 tcaacataac ctcatgtact ggaacaatga ccactatttt gggtttggag ctggtgctag
    28141 cggttatctt ggagatattc gttaccgcaa caaaggacca atccaacact atttacgccc
    28201 attacgagca aatgaacgcc cggtattgga agaagaaaaa ttgacacgaa aaaatcaaat
    28261 agaagaagaa atgttcttag gactaagaaa aaaaacaggg attactaaaa aacatttcta
    28321 tgatcgctat caaaaaacaa ttgaatcggt gtacggtgat gtgctaaggg aattagagca
    28381 agaagggtta cttgttaatg aagaagaccg tgtttatttg acaccaagag ggaccttttt
    28441 ggggaacaat gtgtttgagc gctttttgtt tgaaaaatag tttaaagaat aattgttttt
    28501 tatctgaatt taaataaaaa aagttcaaaa atacaataaa ggactattga aacgttgata
    28561 taactggatt tacatcaatt atttagaatt agcactcttg tgtttagagt gctaaaaaat
    28621 ggagtctttc tcttgacagg agaagggctt cttgctatat ttataagtgg attagcactt
    28681 agaatatatg agtgctaatg agaggtgagg aagatgttaa caaagcgaca aaacgacatt
    28741 ttacgtctga tcatccaaca ctatacgagt agtggcgtgc ccgttggttc caaaacattg
    28801 atgtctgagg gagtcaaggc cagctcagca acgattcgca atgatatgaa agcattagaa
    28861 gatgaaggat tgctgttgaa gactcactct tcttctgggc ggattccatc tgctttaggc
    28921 tatcgttatt acgtggatca tttgttaaaa cctgctcgcg tagcagaaga tgatttgctg
    28981 ctgattcgtc agtctctagg cagagaattt catgaaatca atgagattat taagcaatct
    29041 gctgagatat tatctgagct gacaagctat acgacttttt cattgggacc tgaaataaaa
    29101 gaccgccgac tgactggctt tcgtatcgta cccttgaata atcgacagat tattgctatc
    29161 gtcgtaacag atatggggaa tgtagaaagc caagtgttca ctcttcccga atatatggga
    29221 agtcaggaac tagaaaaaat ggtacagatt gtaaacgacc gtctagtcgg agatcctctg
    29281 atgacggtgt accataaact tcgtacggag attccgatga ttcttcataa atatttccaa
    29341 acgacagaag ggatgtctca gttatttgac accgttcttg gtcatgtttt tgaagataag
    29401 gtttatgtca gtggacaaat gaatctcttg gattatgagc cccgtcaaga tcttgatcag
    29461 ttcaaatcga tgttttcttt tatgaaagac tcagacggac ttacacaaat gatcactccg
    29521 atggatagca atattcatat caagattggt gctgaattag gcaatgattt attgcagaat
    29581 atgagtatga ttcaagcaag ttacgagata gatggtcatg gaagaggtac aatagccttg
    29641 ttagggccta ctagtatgcc ttattctcgg atgttcggtc tagtcgatgt ttatcgaaga
    29701 gaactagcag ctaaacttgc tgattactac cgttcgcttg acttgtcaaa ctcgtaatgt
    29761 gaataacgaa gctatttgca gctgatcgtt ctctctttct tagtaagagc aatcaaacag
    29821 ctgactgaat aatgaaagga agactgtatc gtgaaagaaa atcaagaaga actagataaa
    29881 gaaatgacag atgctcagcc agaaccggaa atcgatgtcg aagctgcaga agattcgggt
    29941 atttcagaag ctgaagcgga agaattcgaa acagcgaaat taaaagctga gttagaagaa
    30001 atggaagata aatacttgcg ggctcgtgct gaaatcgcaa atatggcaaa tcgaggaaaa
    30061 aatgagcgtg agcaattaca aaaataccgt tcacaagatt tagccaaaaa attacttcca
    30121 tcaattgaca acctggaacg tgcattagcc acagaagtgt cagatgatca aggggcaggt
    30181 ttgaaaaaag gcgtggaaat ggtcttggaa agtttgcgta acgcactgga agaagaagga
    30241 attgaaaaaa tccctgctaa aggagaagcc tttgatccta atcttcatca agcagtacaa
    30301 actgttccag cgactgaaga tacaccagcc gatacgattg tagaagtact acaagaaggc
    30361 tacaaattac atgatcgcgt gttaagacca accatggtca ttgttgcaca ataattgtgc
    30421 ggatataaaa cttacacttt caattaaaga aggagacgtt aattatgagt aaaattatcg
    30481 gtattgactt aggtacgact aactctgcag tagcagtatt ggaaggaaac gaagcaaaaa
    30541 tcatcgctaa cccagaagga aaccgtacaa caccttctgt tgtatcattc aaaaatggag
    30601 aaatccaagt aggggaagtt gcaaaacgtc aagctgtgac aaacccaaat acgatttcat
    30661 caatcaaacg ccatatcggt gaagcaggtt acaaagtaga tgtagaaggt aaatcatata
    30721 caccacaaga aatctcagca atgatccttc aatatatcaa aggattcgca gaagactatt
    30781 taggtgaaaa agtcgaaaaa gcagttatca ctgtgccagc ttactttaat gatgcacaac
    30841 gtcaagcaac aaaagatgct ggtaagatcg ctggtctaga agtagaacgt atcgtcaatg
    30901 aaccaactgc agctgctctt gcctatggtt tagataaaac agatcgcgac gaaaaaatct
    30961 tagtattcga ccttggtggc ggtacttttg acgtatctat ccttgaacta ggagacggtg
    31021 tctttgatgt attgtcaaca gctggcgaca accatctagg tggggacgac tttgataaca
    31081 aaatcatcga ctacatggta gcagaattca aaaaagaaaa cagcattgac ttgtctcaag
    31141 acaaaatggc tttacaacgc ttgaaagacg ctgctgaaaa agcgaaaaaa gatttatctg
    31201 gcgtatcaag cacacaaatc agcttgccat ttatcacagc aggagaatct ggaccattgc
    31261 atttggaaat gacattgaca cgtgcaaaat ttgatgaatt aacagctgac ttagtagaac
    31321 gtacaaaagt accagtacgt caagcgctaa aagatgcagg tttatcacaa tcagaaatcg
    31381 acgaagttat tttagtcggt ggatctactc gtatccctgc agttgtagaa gcagtacgta
    31441 aagaaacagg aaaagaacca aacaaatcag ttaaccctga tgaagtagtt gctatgggtg
    31501 ctgctatcca aggtggcgtg atcactggtg atgtgaaaga tgttgtttta cttgacgtta
    31561 caccattgtc attaggtatc gaaacaatgg gtggagtgtt cactaaattg attgaccgca
    31621 atacaacgat tccaacaagt aaatcacaag tattctcaac tgcggcagat aatcaaccag
    31681 cagtagacat ccatgtatta caaggtgaac gcccaatggc tgctgacaac aaaactctag
    31741 gaagattcca attgacagat attccagcag ctcctcgtgg tattccacaa atcgaagtaa
    31801 cattcgatat tgataaaaac gggattgtaa atgtatctgc gaaagatcta ggtacacaaa
    31861 aagaacaaaa aatcacgatc aaatcttctt caggtctaac agacgaagaa atcgaacgta
    31921 tggtaaaaga tgcagaagca aatgcagaag cagataaagc tcgtaaagag gaagttgacc
    31981 tacgtaatga tgtagatgca ttgctattct ctgtggacaa aacattgaaa gaattagaag
    32041 gcaaagtgga cgaagaagaa gtgaaaaaag cagaaacagc tcgcgatgaa ttgaaagccg
    32101 ctgttgaagc aaacaacatc gaagaaatga aaactaaacg cgatgcattg aacgaaatcg
    32161 ttcaaaactt gactgttaaa ctatacgaac aagcggcaca acaacaagct caagaaaacc
    32221 cagaagcagc tcaaggcgga gcagatgatg tcgttgatgc tgattttgaa gaagtcgatg
    32281 gcgacgataa ataatcagtt cactgaattt cgagagaagg ccaaagttgc tactttggct
    32341 ttttcttttg aaaaatagtt tgaagtatcg gtttttgttt caaacaaaat atgatatgat
    32401 aacaagcgac gtgaaaatga tgagaaccaa taggaggaaa gcctatggca acaaaacgtg
    32461 attattatga agtcttaggg ctctcaaaag gagcatcaga agatgaaata aagaaagctt
    32521 atcgtaagct ttcgaaaaaa taccatcctg acatcaataa agaacctgat gcggaagaaa
    32581 aattcaaaga agtatcagaa gcatatgaga ttttaagtga cccgcaaaaa cgcgctgcat
    32641 atgaccaata cgggcatgca ggcacagatc caaattacgg tgctggtgga gctggtggcg
    32701 gatttggtgg attcggcggc ttctctggtg gcggcttcgg tggttttgaa gatatcttcg
    32761 actctttctt tggaggaggc ggtcggtcag tcgatccaaa tgcgcctcgt caaggtgctg
    32821 atttgcaata tacggtcgac ttgtcttttg aagaagcgat ttttggtgta gaaaaagaaa
    32881 tcaagtataa tcgggaagaa atctgtcata cttgtggtgg gaacggtgca aaaccaggca
    32941 cacaaccaac tacttgtcat aaatgtcatg gtgcaggtac gattaatgta gaacgccaaa
    33001 caccacttgg acgagtgatg agccgtcaaa cttgtgatgt ttgtcatggg acagggaaag
    33061 aaatcaaaga accttgtcca acctgtcatg gctcaggaca tgagaagaaa gcacattcag
    33121 ttaaagtgaa tgtaccagct ggtgtagaag aaggacaaca aatgcgttta gctggtcaag
    33181 gagaagctgg agaaaacggc ggaccatttg gtgatttgta tgtggtcttc cgtgtagaag
    33241 aaagtgatat ctttgatcgt gaaggttctg aaatttacta tgaattgcct ttaagttttg
    33301 tacaagcagc tttgggggat gaagtccaag taccaactgt ccatggagat gtgaaattga
    33361 agatccctgc tggaacacag acaggtacga acttccgttt acgtggaaaa ggcgctccga
    33421 agttacgtgg tggtgcaaca ggcgaccaac atgtcaaagt aaaactgatc acaccgaaaa
    33481 atctaaatga acaacaaaga gaagcattac gtgcattcgc tgaagctggc ggcatcaaag
    33541 ttgaagaaca gcaagaagac ggtttcttcg ataagtttaa agatgctttt ggcgggaaaa
    33601 agcggaagta gtttttctag taaaaacgct aagtcattaa taattaaaaa ccagacgaac
    33661 aatcatatgt tcgcctggtt tttttgtagt tgtcatgttt gtaccaacaa aaaagccagc
    33721 tttagaatat gataatcgtc atagtttcta ggggtataac cagtgagaga atggaacttg
    33781 ttcaatcgat attgcaaggt gtttttatga ataaataatt cttctgagca atttttgatg
    33841 cttccgttat ttttactgaa gcatgccaaa gtcttcttga acaaatgtac ttcttcttct
    33901 gtcaggcttt tcaaaatacg ttttacatat aatgttcgtt gatctgacgg gattgctggt
    33961 aaaacgatcc cgaggtctaa atcttcaaaa aagcggatct cgttcacaga ttgatggaaa
    34021 gctatccatt cgcaaacttg tttggcatga aggaaagatt gcggtgtctc ttgctctgta
    34081 taacaaagcg acccaattcc aaagtttagc tgtaactgat acattttatt aaactttgtc
    34141 tggattttat caagcaatga tagcaatgag gctctggaaa tccgattgac taggataatg
    34201 atttgttgtc tatgtacagt gagcaaagcc tgtccgtaat aagagaagac cctttcgagc
    34261 aactccaata aaggattgat ccgttcttga cacaattgct gattgtcaga aagttgtccc
    34321 acaactacat aatatggaga agaaaaatca agctcaatta agtgagggtg gtatcgacta
    34381 tgtacttgat atcatcaatg aaccgatggt actttcttat gcgatggaac aggtagagcg
    34441 attgcttgtt tgtgcaggaa aacaagcgat gcggctgata cgattaggtg agaaaataag
    34501 aagataaaaa tacacggtcc cttcatggcg accgtgcatt tttggttttt attaaatttt
    34561 atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg aagtatagaa
    34621 aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg accgtaaaac
    34681 tactaaggga gataacacga aactgtgtat ctcccgattt ttttatacag ttgattactt
    34741 cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt ctccttttag
    34801 ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag gacgcaagca
    34861 taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca tttcatctcc
    34921 gcttgacgct ttgcaaatca attcaaaaga
//
LOCUS       DAZKPE010000025        33821 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000025 DAZKPE010000000
VERSION     DAZKPE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.025"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            73..1038
                     /locus_tag="ACG930_001329"
     CDS             73..1038
                     /locus_tag="ACG930_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFQ0518497.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(1095..1325)
                     /locus_tag="ACG930_001330"
     CDS             complement(1095..1325)
                     /locus_tag="ACG930_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFQ0518498.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1411..2298)
                     /locus_tag="ACG930_001331"
     CDS             complement(1411..2298)
                     /locus_tag="ACG930_001331"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0518499.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(2387..3610)
                     /locus_tag="ACG930_001332"
     CDS             complement(2387..3610)
                     /locus_tag="ACG930_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0518500.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(3627..4673)
                     /locus_tag="ACG930_001333"
     CDS             complement(3627..4673)
                     /locus_tag="ACG930_001333"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFQ0518501.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(4837..6564)
                     /gene="ptsP"
                     /locus_tag="ACG930_001334"
     CDS             complement(4837..6564)
                     /gene="ptsP"
                     /locus_tag="ACG930_001334"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFQ0518502.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(6564..6830)
                     /locus_tag="ACG930_001335"
     CDS             complement(6564..6830)
                     /locus_tag="ACG930_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFQ0518503.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            7309..9543
                     /locus_tag="ACG930_001336"
     CDS             7309..9543
                     /locus_tag="ACG930_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0518504.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            9691..10011
                     /locus_tag="ACG930_001337"
     CDS             9691..10011
                     /locus_tag="ACG930_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFQ0518505.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(10216..10440)
                     /locus_tag="ACG930_001338"
     CDS             complement(10216..10440)
                     /locus_tag="ACG930_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFQ0518506.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(10638..12218)
                     /locus_tag="ACG930_001339"
     CDS             complement(10638..12218)
                     /locus_tag="ACG930_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFQ0518507.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(12619..13995)
                     /locus_tag="ACG930_001340"
     CDS             complement(12619..13995)
                     /locus_tag="ACG930_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFQ0518508.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(14123..15211)
                     /locus_tag="ACG930_001341"
     CDS             complement(14123..15211)
                     /locus_tag="ACG930_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0518509.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            15383..15817
                     /locus_tag="ACG930_001342"
     CDS             15383..15817
                     /locus_tag="ACG930_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518510.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(15895..16428)
                     /locus_tag="ACG930_001343"
     CDS             complement(15895..16428)
                     /locus_tag="ACG930_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFQ0518511.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(16522..17700)
                     /gene="mutY"
                     /locus_tag="ACG930_001344"
     CDS             complement(16522..17700)
                     /gene="mutY"
                     /locus_tag="ACG930_001344"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFQ0518512.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(17693..18490)
                     /gene="recX"
                     /locus_tag="ACG930_001345"
     CDS             complement(17693..18490)
                     /gene="recX"
                     /locus_tag="ACG930_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFQ0518513.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            18597..19979
                     /gene="rlmD"
                     /locus_tag="ACG930_001346"
     CDS             18597..19979
                     /gene="rlmD"
                     /locus_tag="ACG930_001346"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFQ0518514.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(20153..20731)
                     /locus_tag="ACG930_001347"
     CDS             complement(20153..20731)
                     /locus_tag="ACG930_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFQ0518515.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            21053..21523
                     /locus_tag="ACG930_001348"
     CDS             21053..21523
                     /locus_tag="ACG930_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFQ0518516.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(21631..22857)
                     /locus_tag="ACG930_001349"
     CDS             complement(21631..22857)
                     /locus_tag="ACG930_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0518517.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(23611..23811)
                     /locus_tag="ACG930_001350"
     CDS             complement(23611..23811)
                     /locus_tag="ACG930_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0518518.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(23945..24553)
                     /locus_tag="ACG930_001351"
     CDS             complement(23945..24553)
                     /locus_tag="ACG930_001351"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFQ0518519.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(24638..25108)
                     /locus_tag="ACG930_001352"
     CDS             complement(24638..25108)
                     /locus_tag="ACG930_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFQ0518520.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(25156..26070)
                     /locus_tag="ACG930_001353"
     CDS             complement(25156..26070)
                     /locus_tag="ACG930_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0518521.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            26216..27019
                     /locus_tag="ACG930_001354"
     CDS             26216..27019
                     /locus_tag="ACG930_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFQ0518522.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            27197..28144
                     /locus_tag="ACG930_001355"
     CDS             27197..28144
                     /locus_tag="ACG930_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFQ0518523.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(28212..28505)
                     /locus_tag="ACG930_001356"
     CDS             complement(28212..28505)
                     /locus_tag="ACG930_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFQ0518524.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(28533..29198)
                     /locus_tag="ACG930_001357"
     CDS             complement(28533..29198)
                     /locus_tag="ACG930_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFQ0518525.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(29338..29970)
                     /locus_tag="ACG930_001358"
     CDS             complement(29338..29970)
                     /locus_tag="ACG930_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0518526.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(29977..31044)
                     /gene="liaS"
                     /locus_tag="ACG930_001359"
     CDS             complement(29977..31044)
                     /gene="liaS"
                     /locus_tag="ACG930_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFQ0518527.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(31041..31772)
                     /gene="liaF"
                     /locus_tag="ACG930_001360"
     CDS             complement(31041..31772)
                     /gene="liaF"
                     /locus_tag="ACG930_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFQ0518528.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(31941..32420)
                     /gene="greA"
                     /locus_tag="ACG930_001361"
     CDS             complement(31941..32420)
                     /gene="greA"
                     /locus_tag="ACG930_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFQ0518529.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(32556..33731)
                     /gene="mltG"
                     /locus_tag="ACG930_001362"
     CDS             complement(32556..33731)
                     /gene="mltG"
                     /locus_tag="ACG930_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFQ0518530.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT        10089 a         6864 c         5604 g        11264 t
ORIGIN      
        1 aattccctaa aacttgtcca ttatttcaaa atttgttata gtctttttat tcaaagcgta
       61 aaaggagatc ctatgttaaa agaaaaaatg aaaactctcc ccatgctgcc gggtgtctat
      121 cttatgaaag accgagatgg taaggtcatc tatgttggta aagcaaaacg gctcaaaaat
      181 agagtaagca gctattttca tcagaataaa cagcattcaa aaaaagtatt acgtatgatt
      241 catcatataa cagattttga tttcgtcgta gtagacacgg aattagatgc tttattgctc
      301 gagtgtcaat tgatccaaca ttaccgtcct ttttataacc gacaaatgaa ttatttcagt
      361 aattataatt atgtacatat taccaataag ggatttgtat taacagatac tcctacggct
      421 cgaacatacg ggccttttcg tctctataaa aaaatgccgt ctattttgcg tataatggaa
      481 gaaacttatc aaatgccttg gttgtctgaa attagtttgt tagctttgcg agtccagctt
      541 cctgacctac aggaaatgac ttttgaacag aaaaaaaagg aactccaagg gctgtttcaa
      601 ggccgaaata aaaagctact gacttacttg aaaaaaagac aacaacattt catctatcag
      661 ttgaatttcg aaaaagccgg tatgcttcaa aaagatatcg aattagttac ttattttatt
      721 agacggatcc aggaacaaaa gcagttttta agaacaccat cgctcacctt cagcatgcca
      781 ttagcagcag atgagagtca gaaaaagcac tacctcgttt gttatggtca acttgcagaa
      841 acaatgatta cctctggtga cgtttctcct gacttctatt atgaaaagaa agaagctcat
      901 ttatctttga aacgtcaatt gtcaaaagaa gaaatcgatc ctgtacaaat cttgatcagt
      961 taccgcaaaa aattagaaaa agaacagttt gaaattgaac tgttaaacaa aaaagaagct
     1021 gaaaagcaac taaattagtt gcttctcggc ttcttttagg catcttcaac ttcaaatgtc
     1081 aattatccta aaatttattg gattaagtca tagatttcca tcgctacgat atcgatatta
     1141 tcaaattcgt attgctgatg agtatctgtt tcagttaatt caaatgtatc ggtcgcttta
     1201 tcataagtta ctgtacactt ctctacgcct tctttttcaa aacggcgaac ttgcagttca
     1261 ttatctgctg actcgaccat agcctccagt cgttttatga ttgcgactaa ttgtgaatgt
     1321 gtcatcggag gtcctccttt tcttatttct gttatattgt atcaaaagca tagcctactt
     1381 gcattgattt tctctaaaaa aactcgtttt ttatgatttt ttttctggta tttttccttc
     1441 aggccaccaa agtttgatca aagcttgggt tccgtcattc tcaaaacctt tatctgccaa
     1501 ctcttcatat agtttcaatg cttgggtagt tgctggcaat acaagatcca ttttttctgc
     1561 ttcttctaat gcaatcttta aatctttgat aaaatgtttg acaaaaaaac caggtgtgta
     1621 atcttctttt aaaatacgag gagaataatt gcttaaagac cagttagctg cacttccacc
     1681 tgaaagcgtc tcaatcactt tctttaaatc aagtccgttt ttttgtgcat agacaagcat
     1741 ttccgtcatt cctgtcatcg tacctgcaat catgatctga ttagccattt ttgtatgctg
     1801 acctttccca gcagaaccat gcaatgtaaa tgtcgtacca aattctttga ataaaggcag
     1861 tacttgatca taaacggctt cttctccacc gaccatgatc gtcagtgtac cattctttgc
     1921 tcctaagtca ccaccggata ccggtgcatc taacgcatct gcgccttttt cttttgctgt
     1981 ttttgcaatt ttttctgcca ggcttggtgt acttgtagtc aaatcaacta aaatatgtcc
     2041 tgagatatct gcagaaaaaa tccccgactg tccatagtag atttcttcta catctttggg
     2101 gtaacctacc attgtaaaga gaatattact ttgttctgct accgcttttg gtgtatctgc
     2161 ccagatagct ccttctgtta ctaaaggatc agcttttgct tttgtccgat tatagacagc
     2221 tacttcgtgt cctgcttcta gtagatggcg tgcgacagca cttcccatga cgcctgttcc
     2281 gataaaacca agtttcattt tttcgacctc ctaaaaatca aaaatccttg cttctatgct
     2341 agtatacgct agaaacaagg attttttcat aaaaaatgtt tgaattttat cttttaaatg
     2401 aatttaattt tattttgatt cgttcaatcg agtcttcttc ttcttttctt cgcatctctt
     2461 cttcatgata aacaaccatg tcttgataaa attcgatcat agcttcgccg aaatgtgtag
     2521 atgaaatatc ataaagttta gcttctaaaa cttttggatc tttaggaact tcactggaaa
     2581 tataatcaat aagtgctggt gcaaagtctt cgtcggtttc aaaagttttc cctaatgaag
     2641 gatgatcgaa caatcggttc aaataagcat ttccttccac gacacaaggt gttccggctg
     2701 ccatcgcttc tgtataagta agcccttgtg tttctgaagt agaagcactg acaaaataat
     2761 ctgccgcttt ataataaagt gctacatcat tgttgtccac ttctcctgtg aactgcacaa
     2821 attcttctaa ctgcagttct gagatcaatt cctctaactc ttctacataa ggtccttttc
     2881 ctacgataac taatctggcg ttaggataag cggagatgac ctgaggaaac ccattaatca
     2941 aggcttggat atttttctca taagaaatcc tgcttaaaga aagaatcatc aaatggtttt
     3001 cctgaagacc tagtgactcc cttaatttgc tgatatcctg ctgagtgata tcagaacgtt
     3061 tgaatttttc aatgtcgata ccagtaggaa tcacgcgaag cggtgctatt acaccatagc
     3121 tgcgtaatgt atcaataaca cgttcacttg gacaaactac acctgtcgta tgatttgcaa
     3181 ataatctaga caagtatttt acatgggatt gcctgatcac ttttccttta ccgatataat
     3241 gaaggtagtc ttcatacatc gtatggtaag tatggatcag aggtattttc aacttcttag
     3301 ctaccatctt cccaagtatc cctgctccga attctgtatg ggtatgaata agatctagtt
     3361 ctagttcttt ggcaaccaaa taagcatacc acatgcctct aacaacaact cttcgatcct
     3421 tgaaagaaat aaatggtaca cttggcattc gaatcacatc tttttccaac ttatccgcat
     3481 taggatcggt cgttgtaaaa atatagactt catgcccatg tctttctaat tcttgtttta
     3541 atgttttgat cgatgtagca actccgctga cttgcggaaa gtaggtatcg gtaaaaaagc
     3601 cgattttcat gtttttcgcc tccaaactag tccttgacct gatttacttt ttttaatttg
     3661 ctagagactt tttcattcag tacactttcg tatacatttt taagttcttc accgatttta
     3721 ttgatacttc gctcttttgc tgtttgataa ccggcttgtg tcgtactcgg tagttcttga
     3781 ttggtaatct gttggatcag tcggataaat tcttcgtttg tcttccccat atagcagttc
     3841 ttgctatctt ctaaccagcc attatacact ggaatatctc gaacaagtac gttttgtttg
     3901 cttgctaaag cttctaaaac aacgatccct tctgtctctt cataagaagg gaaaaagaat
     3961 agatctgcac ctgaatacgc accttctatg atctctccac gaatgtaacc aggaaacagg
     4021 acattttcag gatgatcttc ttttacaatt ttccggatgt tccgaggaat cgagtacatg
     4081 ggaacatgac caaaccaaat aaatgtgtat tcgggcatct tcttagcaat ttctacgaaa
     4141 tcaatgattc ctttacgttc gaaaaacaaa ccgacacaaa tgattacttt ttgatccgga
     4201 gacagtttga aatattctct gaacttttgt tctttcattg gatcagggtg atatttctct
     4261 aagtcgatcc cattggaaat agcttgaatc ggcacacgga taccatagct ttccaacaac
     4321 tgttttgaat aaggtgttgg cgtgatcaga tagtccgctt tttggtacaa tcctaccaga
     4381 tattttttta cgataggaga aagctggttc gatccgataa aggaatttcg gaaatcttcc
     4441 tctgtagaat gcgcatgata gacaactttt tttccttctc ttctggcttt attgaccata
     4501 ttatgactat tgattccgta tgtattgatg tgcaggatgt cataatcttc tttttcatct
     4561 agtgtataag agataccgac ttccgtcaga gcacgttttt gatgatcaag cgcacgcccg
     4621 attccagatt ttgcaagcat cttttcactt tcaaaatata ataatacctt caccttacgt
     4681 cccccttcac ttatatagta taacatagcc tacaaactgt cactcaaact taagccctat
     4741 ttttgtctat tcttactgac aaaaacgttt tcttaaaaaa gaacaaaaaa actggcgtag
     4801 ctcttttaca agccacacca gcttttgata cgttgtttat tttacatatt catgaacaag
     4861 ttcaacgact tcttccatca tatcgcattc tttcaatgca cgatcagcaa gttcagccat
     4921 tttcgctgtg tccaagcgtt tcattaaact acgcgtttta agaatagatg tcgcactcat
     4981 tgagaactca tctagaccca tacctactag caatggaaca gctgtttgat ctccagccat
     5041 ttctccacac atacctgccc attttccttc agcgtgtgct gcatcaatta catttttgat
     5101 caaacgtaaa attgatgggt tatatggttg gtacaagtaa gaaacgcgtt cgttcatacg
     5161 gtctgctgcc attgtgtatt gaatcaaatc gttcgtacct acagagaaga aatctacttc
     5221 ttttgcaaac ttgtctgcta agactgctgc tgctggaatc tcgatcatga tgccgacttg
     5281 gatcgtatca gatacttcct tgccttcact tatcaatttt tgtttttctt cttcaaagat
     5341 cgcttttgct gcgcggaatt ctttgagtgt agctaccata gggaacatga tacgtaaatt
     5401 accatgaaca gatgcacgaa gcaatgcacg catttgtgta cggaacattt cgtcgccttg
     5461 ttcagataaa ctgatacgca atgcacgata tcctaagaat ggattcattt catgaggtaa
     5521 ttgcagatat ggtagttctt tatctccacc gatgtccatt gtacgaacaa ctacaggttt
     5581 tccttccata ccttctaata cagctttgta agcttcatat tggtcatctt ctgttgggaa
     5641 gtctggagaa tccatataca ggaattcagt acggtacaga ccaactgctt ctccaccatt
     5701 attatggaca ccaactagat cttttggtgt tccgatgttt gcagctaatt caaaatgctt
     5761 gccgtcagct gtgacagttt ctgcattttt taatttttcc cattctgctt tttgtgctgc
     5821 gtaatctgca cctgcttttt caaattcagc tttttgttca tctgtaggat cgatgattac
     5881 atcgccttcg atcccgttga cagccaaaat atcgccttct ttgactttag cagtaatttc
     5941 ttttgtccca acgattgctg gaatttctaa agaacgtgcc atgatagcag aatgtgaagt
     6001 acgtccacca atgtctgtta caaacgcttt tacaaaattg cgatctaatt gtgctgtatc
     6061 acttggagtc aagtcatgtg caacaacgac cacttcttcg ttgatcattg atggatttgg
     6121 taaagtaacg cctaataagt gcgctaaaat acgtttagca acgtcacgaa tatctgcagc
     6181 acgctcttgc atataagcat tatcttccat tgcttcgaac ataccgatat acatatccgt
     6241 tacttctttt agcgctgatt cagcatttac gctgttgtct ttaatatttt gcttgatttg
     6301 acctaccatt tctggatctg aaagaaccat caaatgggca tcaaatactt gcgcttctgc
     6361 ttcacctaag ctttgcgctg ctttttcacg aatttgctgc aattcttcag tagatttagc
     6421 taatgcagca tccaaacgag cttcttcagc cgcagtatct tctactgttg ccttactgaa
     6481 tgttaaatcc ggttgaacta gcaggtaagc ttttgcaacg gctacaccgt cactagcggc
     6541 aatccctttt agcatttcaa ccattattca gataagcctt ctttcttcat tgtttcaacg
     6601 attgctgcca ttgcatcagc ttcgtcagca ccttctgcag taatagtaac atcagaacct
     6661 tgacctacac ctaaagacat aacgcccatg attgatttca agtttactga tttaccttta
     6721 tactctaagt ttacatcaga gttaaatttg cttgctgttt gtactaatag tgtagctgga
     6781 cgagcgtgga tcccagtttc tgctactacg tgaaattctt tcttttccat attaatcggt
     6841 ctcctttaag tgagtgttgt ttttatgtga gggttttctt ttttagtaat tcagagaatc
     6901 ctaacaaatg ccaccctttc atctgtaaag attaacattt tttttcgtta gatacaacag
     6961 ttttcattca atttcagata aaagtattca aattattccg gattcttttt catccttttc
     7021 ttcacatttt ataacaaacg tgtttatttc ctttttcttg tcgctttctc ttctcctgac
     7081 gtttatcatt ctttcctttg accctctttg ttttcatatg aaacgaatta cttgcttccc
     7141 tttttatttt tagtataata agagtcaaag gtcaggaatg gtcaatagag atttcacctt
     7201 ttctacctca taaatctctt aaaaaactag gggttattct tttacctcat gaaaaacgag
     7261 atgtaaaata tggatgtacc catttttgtg aaaggacgtg aatgattcat gctttgtcaa
     7321 aactgcggca agaatgaggc aacgattcac ttgtatgcca ctgtcaatgg tcagcggaca
     7381 caactcgatt actgtcagag ctgttatcaa aaaatcaaaa atcaacaaaa tggaggtctg
     7441 actaatatgg cccaaaatga tccatttgga tttggcagtt tggacgatct tttccgttcc
     7501 atgtctcgcc aaatgcaaca gcaaggaaat tatgagcaaa caccaccaac acaatttggc
     7561 ggaaacaaca acttcaatgg tggtcagcca cctcaaggca atacagaagg tttattggga
     7621 gaatacggaa tcaatatcac agaacaagca cgacaaggtg atatcgatcc tgtgatcgga
     7681 cgcgatgacg aaatcaaacg agtcattgaa attttaaatc gccgaaccaa gaacaatcct
     7741 gtcttgattg gagaaccagg tgttggtaaa acagcagttg ttgaaggttt agcacaaaaa
     7801 atcgtagatg gtgatgtacc gcaaaaatta atggacaaag aagtcattcg tttagatgtc
     7861 gtatctttag tccaaggtac tggtatacga ggacaatttg aagaacgtat gcaaaaattg
     7921 attgaagaga tccgtcaagc agaaaatgtg atcctattca tagatgaagt tcacgaaatc
     7981 gtcggtgctg gttctgctgg tgatggaaat atggatgctg gtaatatttt aaaaccagct
     8041 ttagctcgag gagaattgca aatggttggt gctactacct taaatgagta ccgcatcatc
     8101 gaaaaagacg ctgctttaga acgtcgtatg caacctgtac gggtagatga accaactgtc
     8161 gaagaaacga tcagtatttt gaaaggtttg caaaaacgtt atgaagacta tcatcatgta
     8221 aaatatactg atgaggccat cgaagcagcc gcaactttat ccaatcgtta cgtccaagat
     8281 cgcttcttgc cggataaagc catcgatttg ctagatgaaa caggttctaa gaaaaacttg
     8341 acgatccaaa tcgttgatcc taaaacaatc gagaaaaaac tgcaagaagc agaagaacaa
     8401 aaagttttag cttctcgaga agaagatttc gaaaaagcag cttattatcg cgatcagatc
     8461 aataaacttc aaaaaatgaa agaacgtcag ctcactgaag aggaaacacc tgtgattacc
     8521 gaaaaagata tggaaaaaat cgttgaacaa cggacaggta ttccagtggg tgaattaaaa
     8581 gaaaaagaac agacacaact gaaaaactta gcagatgact tgaaagctca tgtcatcgga
     8641 caagataacg ctgtagatcg agtagcgaaa gcgattcgcc gaaaccgtgt tggattaaac
     8701 aaacagaatc gtccaatcgg ctccttctta tttgttggac caactggtgt aggtaaaaca
     8761 gagcttgcga aacaacttgc ctacgaacta ttcggttcac aagattcaat gattcgtttc
     8821 gatatgtctg aatatatgga aaaacatagt gtctctaaat tgattggttc tcctccaggt
     8881 tatgtcggat acgaagaagc tggtcaatta acagaaaaag tacggagaaa tccttacagt
     8941 cttgtcttgt tagatgaagt agaaaaagct catccagatg ttttgcatat gttcttgcaa
     9001 atcttagatg atggtcgatt gacagatgca caaggaagaa cggtcagctt taaagatacg
     9061 atcatcatta tgacaagtaa tgccggaact ggtaaagtag aagcaaacgt tggttttggt
     9121 gcggcacgcg aaggtgttac tcgttctgta ttgaaccaat taaacaacta ctttacacca
     9181 gaatttctga accgttttga cgggatcatc gaattcagtg cattatcaaa agaaaacttg
     9241 atgacaatcg tcacactaat gctagacgat gtcaaccaaa tgctggcagc acagcaactt
     9301 cacatcgaag ttcctacgaa tgtcaaagaa aaattagttg acttaggcta tgatccatct
     9361 atgggtgctc gtcctcttcg acgcacgatc caagaacaaa tcgaagatgg tatcgctgaa
     9421 ttttatcttg atcacccttc tatccatgag ttgaaagcaa aactggataa agatggaaaa
     9481 atcatcgtta cttctaaacc agaacgtttg gctaaagaat cagccgaaga aacggctgaa
     9541 taaatccagt tttatagcgt gagacggtat ttctttgaga aatgccgtct cattcttttt
     9601 tcagaaaagt caaaatactg ttcattttat aaaaaagaaa ttataataag agaaacaagc
     9661 aattaaaaat acataaaaga ggtgagcgcc atgaaattgg taaatgtaac aaacagccat
     9721 tcccgtcttg tattaaacca gcttgaaaac actgatgccc atctagtcaa ggtctacaca
     9781 gccggaaata ccactattgt ctacactgaa gcccctgaac ataatgaaat tctgctgatc
     9841 aatgacaaac gtaaaatcca gccgaaagaa atcgaagatg ctaaaaatta tttcttagat
     9901 aaaatcaaag acgccgttta ccacgaggat gaaatcaaag taatcgaatt ggcaggcctt
     9961 gttgaaatct cgattccaaa acatgaatta ggcgctacat tagccgtgta aacaaatttt
    10021 gaacataata attaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    10081 acacgtataa acggcgaaag cagaagcaac tccttcggaa ataagctgaa attcacgaaa
    10141 attgcttttc aaatttttgt gaattccagc ttatttcttg gagttaaacg cttctgtctc
    10201 agcctctttt tctttctagc tttttgattt ttctcttttc ttttgtactt ttctcttttc
    10261 attttcagtt ctacgcgtgt ctttattttt aactttttcc tctttatgga tgattgatcg
    10321 tactttttgt gcaatttgct cgtttttgtc ccagtctttt acatctaata atcgacataa
    10381 tcgtaacatc tcttcttttt tctgtttttt tctttcacgt ctttgccatt ctgtttccat
    10441 gtgtcacact ctcctttctt taatcatatg tacgcaaaat aatttttata tttttttgat
    10501 tagacatttc tatgatttta atatagtaaa aagagccgtc acggaaaatc cgtcacggct
    10561 ctaaacaaaa tatgagaggc tgtttttgtt tggctattct tattacttga tgcagggcag
    10621 cttgtgtcaa gacttcttta catcaaactt tttaatttta cattgggata tttatccgca
    10681 aaccagcgtt ctgcaaattg gttctcgaat aagaacaacg gttggtcgaa acggtcacga
    10741 gccaagatat tgcgacttga actcatcttc tcatccaaat cttctggatc gatccagcga
    10801 gcgattttgt gtcccattgg agacatgatt acttcggcgt tatactcatt taacatacga
    10861 tattggaata cttcgaattg tagctgacca acagctccaa tgatatattc ttccgttaga
    10921 tatgttttat aaagctgaat cgctccttct tgaactaatt gatagattcc tttgtggaag
    10981 gatttttgtt tcatgacatt ttttgcagtc actttcataa acagctctgg agtaaatgaa
    11041 gggagttctt cataagcaac ttttagtttt ccttcgaaca atgtatcccc aatctgataa
    11101 ttgcctgtat catatacacc gatgatatcg cctgctactg ctttttcgac gttttctctc
    11161 gaatctgcca taaattgtgt gacattgctt aatttcagtt ttttatttgt acgttccaac
    11221 cagacatcca ttcctcgttc gaatgttcca gaacagattc ggacaaaagc gattcggtca
    11281 cgatgggctg gattcatatt tgcttggatc ttgaatacga aacctgaaaa ttcttcctca
    11341 taaggactta ccatctgatc atcttgtgtt ttgtgtccat aaggagctgg tgccaattca
    11401 acgaaagtct ctaaaaaagt ctgtacaccg aagttagtca atgcagaacc aaaaaatact
    11461 ggtgtctgat cgccacgagc aattttttct tgattaaatg catctccagc ctctttgatt
    11521 agttctactt cttctaagac ttgttcatat aaggaatttt cagttagagg atgattttcg
    11581 ggaagcagtc catcttcatc caattctact aatcgttcat cctgataatt ttccggacga
    11641 taaaactcta cacgattatg gtagatatca taaagacctt ctagcccttt acccataccg
    11701 attggccaat tcatcggata agattcgata tctaatagct cttctaattc ttctaacaat
    11761 tccaatggtt cacgaccatc acgatctagt ttgttgataa aagtaaatat cgggatgcca
    11821 cgttttttta caacttggaa taatttcttt gtctgtgctt cgatcccttt tgcactatcg
    11881 attaccatga ccgcactatc cacggccatc aaagtacgat aagtatcttc agaaaaatct
    11941 tcatgtcctg gtgtatccaa gatatttact cgtttccctt gataatcaaa ctgcataaca
    12001 gaactagtaa cagaaatccc acgttgtttc tcgatttcca tccagtctga tttggcaaaa
    12061 ttacctgttt ttttgccttt tacggtcccg gcttgacgga tagccccacc aaacaatagt
    12121 aattgttctg taatcgttgt tttcccagca tccggatggg aaatgatcgc aaaagttctg
    12181 cgattgtcca cttgttgctt taattttgga ttattcataa cctaactcca tttcttccat
    12241 tcaattattt atattttctc taggcacaga ttgtccgatc tcttaaagaa agacaatttc
    12301 atatagggct gtgacaaaag ccgtgtagca gtctcttttt ccgagtaaac ggcgttctag
    12361 agacagccta tcagcaataa gcccacccaa gccaaaaata cgaaaagctg tttttgcttg
    12421 gctgctctta ttacttaatg caggatagct ttttcacaac ctttgtcaac tactacaact
    12481 gaatcagtat agcatggatt cagcgaatga aaaagccacc aaaccataag agtcaaatat
    12541 ttttttgtca gctgactaaa agaaaagacg tgttgcttgt ttattcaagc aacacgtctt
    12601 tcataaccaa gtttccaatt atcttcttgg ctcgtcatct tcgaattctt ttctgaagta
    12661 tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga tcatgaaaaa tgacacggat
    12721 tttaaggatt cgagaacctt ccatttcttc agaaaccagc gtaatattat cgacatcaaa
    12781 cgataacttt tcgccttcat ccggaatcat gcctaatgct gtaatcaaat aaccagccat
    12841 cgtatctaca tcactcatat gcagatcact gtcaaaagct tcattgaact catcaatcag
    12901 catacgtcct tggatgatat attcgtgttc atcgattttt tcataaagat tctcaacttc
    12961 atctgattca tcatcgattt ctccgacgat ttcttctaaa aggtcttcta gtgttgctaa
    13021 cccaacgacg ccgccatatt catctaataa aatagccatc tgattctgcg tctttttcat
    13081 ttcatataac agatcatcaa taaagaccgt ttcaggaacg aataaaggct cctgcatgat
    13141 tttcttgata tctaaattat caaagccgaa tttatgggca gcttttagta aattctttgt
    13201 atgaaggatt ccgactactt tatctttgtc ttcgttataa acagggattc ttgaatagtt
    13261 ttcggataaa acttcattca cattttcttc cacagtgtcg ttgatatcaa tcataaatgc
    13321 atccgttcgt gggaccatga cttctcgggc aactttcgta tcaagagaaa aaaccccttg
    13381 gagcatttct aattcttcat tattcaatac gccttcgttt tcaagcatat aacgcatttc
    13441 atctctggtc atttttgaat cttcatcatc aaaagtcatc ggcgtgatac gcgccaataa
    13501 acttgtggaa gcagaaagca gccagacgaa gggcttagct actacaccaa tcaagcgtat
    13561 cagccctgaa gtgaactttg cgacttcttc tgatttattt aaagcaatac gtttagggta
    13621 caattctcca aaaacaatcg atacataggt caaaatagcc agcacaatga tatttgcaat
    13681 attttttgcc gctgtgccgc cacctaatac cggagctaac cgttccgata aagtattagc
    13741 tagtgaagca ccagacaaaa tgttgaccaa agtgattcct acttggattg tcgataggaa
    13801 attatttgga ttctgcaata tttttaaaag cttttgagat ttcacatctc cttcatcagc
    13861 tttttgctcg attcgattct tattgatcga aacaacagca atttcggaag ctgctaaaaa
    13921 agcattgatc aatgtcaaaa cgatcaataa taaaatctgc gctaacagcg actgactctc
    13981 agggtcagca ttcataatcg cattctctcc ttataaaatt aatttttagt ttacgataga
    14041 aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca aagcaatttt ctttgcaata
    14101 aaaacaagtg tactaaaact acctacgagg tcgtagcaat tttcttcttg ttttcatttt
    14161 gcttgtcttc tttgacgatt ttgattatat aggaaatgat cgtcttgcag attgcgtaaa
    14221 aaggaacacc taagaagata ccaagcaatc cggcaatatt tccagctact agaagaacga
    14281 taatgatcgt taatggatgg attttcagtg atttcccaat tacattagga taaatgatat
    14341 tcccatccaa ctgttggacg attagcacaa ccacacaaca aagtaatgct tttaccggat
    14401 cattgaagac tgttactaga aatgcaggtg ctagtcctag ataaggtcct aaatatggaa
    14461 ttaggtttgt caatcccgca atgaccccaa ataagaaagc ataatccaca ccaattacca
    14521 tatatcctaa aaatgtgaag gtaccaacga ataaacattc gattgcttgt ccgctaatgt
    14581 aattagccaa tgttttattc agttgcccca ataactccac aatttggttt cttctttttt
    14641 ctgggaaaaa ctgttggatg tttggcacta gtttttctcc gtctttcaac atatagaaca
    14701 agatgaatgg tgctgtaatg attactacgg ttgccgaagc gatcgttcca acgatcgaac
    14761 ctaaactatt ggatactcca ctaaggaatt gctgaatgat tgtcccgtaa gaaatgtcta
    14821 attgctcaaa atatttattg atatctactt ccttgaacaa aggcaattcg gctacctctt
    14881 ttaaccagct ttctacctgt ttgatgaaat caggcatatt agatgccaat gaggaaattt
    14941 gctgtactag acttgggatg acactaagta aaatccaaat aattgctgca actaaaagga
    15001 gcagcacaat tgcgacagcc catattcttt tgatttttgc tttcatcaac agcttgacaa
    15061 taggattcaa taaatagtaa agaaagcctg caatcagtac aggtgcaaat aacgtggaaa
    15121 aaaatgtccc gatcggttcg aaaataaagt ttatttctga tgaaatcatg atcaatgcag
    15181 ctatgatcaa taattcaagc gaccaaaaca ttagtttaga ctgtctaagt ttttcaaaca
    15241 atagatttcc tcctttcttt cttactagta tatattatat tcgttaaaaa ttcttttatt
    15301 ctttttttat ttttgaaaac ttgccatact ttttatttgt tttattttcc agtatactat
    15361 acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca aaagatacaa tgagcaatat
    15421 ttacttagat gctgtacgga tcaggcatca agtttttgta gtcgaacagg gtgtgccttt
    15481 gtctcgagaa atagacaaag atgaagccca ttgtatccac ttcgtcctgt actcagataa
    15541 aaaagaaccg caaggaactg tacgtctttt gcctttagaa aacggaaaaa tgaaattaca
    15601 gcggatggcg attctttctg aatacagaca ccaagggtta ggaaaaatat tgattgaaga
    15661 agcagaaaac tttgctaaga atcaaggcta taatacgatt ttattagggg cacagtccac
    15721 agctgaaact ttttacgaaa aactaggata tacagcttac ggcgatcctt ttgaagatgc
    15781 tggcatgcct catatttata tgaaaaagac tttataaaaa tttatttcga aaaaagcaaa
    15841 aaacagcaag cttttgagaa aaatctctca ctggcttact gttctttttt gtgtttactt
    15901 acgcgacaat tgcttgtaac ggttatacca aatatcaata tagccttccg agaacgggcc
    15961 atctccatta ttgatccagt caaccagaat cttcacattt tcttttagga tgaagtcaat
    16021 atcgttcggg taattcatca ttttgctgtg catctcatat tcatcgacat ccaatagtcg
    16081 tttctcgccg tcaggaaata ccttgatatc caagtcatag tcgatatatt tcaaggcctc
    16141 atcgtccagc aaaaaaggtg aagctagatt acaataatag gaaaccccct tttctctgat
    16201 cattgctatt acattgaacc agtatttttt atgaaaataa acaatcgctg gttcgcgcgt
    16261 tacccatcgg cgtccatcag attcagtgac taatgtgtga tcattcacgc cgatcataga
    16321 gtgttcgctt gtttttaata ccatggtatc tcgccacgtt cgatgcaatt tgccgtcgtg
    16381 cttgtaactt tggatcgtca caaactctcc ttcttttgga actcccatag caacccttcc
    16441 ttaagcagca ttttgtgctt tgtgtttggg tgttcattac accgacatca taattattat
    16501 atcaataaaa atgagctttg cctagaaagg attcctattg tttcgatttt tctctaactg
    16561 atctaccagt ttcatttgga ccttaggaaa aacgaccgaa tcaaatgcat caggcttcaa
    16621 ccacttcgaa gttttgttct cggtaaattc ttgttctgct ccctcggttg cccgtccgta
    16681 aaaaaggaga acatgccatt tcagatgact aaaaatatga gtaacttctc ctaaatgtcg
    16741 tgtctgccaa acaaagagtt cctgcttttc aaatgggaga ttttgctctt cttctgctac
    16801 taggtcatca aacagatcga tttctggctt tgtttcccat tcttttttca atcgctcata
    16861 ctcctcttgt gtcacttcca tcattggaaa tgtccacata ttcgccagca atttttggct
    16921 atctctttct tcaaaataat acgctccaga atgattttga agagctgcac tgatataata
    16981 aacgtctttt ggctttgctt tttttgtttt tacaggaaaa ctcgtttgga ttcctcgttt
    17041 gttagctaaa caaaaggctt ggatcggaca agtctcacac tttggagaag ttggtgtaca
    17101 gatagctgaa cctagatcca tcattgcttg gttgaattca cctggatgct tttcatcaat
    17161 gattttccgc atcgcttcat caaagatttt cctgctagaa gcttttgcga tgtctgcttc
    17221 aatgcaaaac aatctgctga ctactcgcat cacgttgccg tcaactgcag gttctggaag
    17281 tccaaatgcg atacttgcaa tcgcgcctgt cgtatatggt cctattccct tcaatgagct
    17341 aatttcttca ggcgtttgcg gcatttcccc atcaaattct gacatgatct gtttagcagc
    17401 agcttggatg ttccgggctc ttgagtaata accaaggccc tcccatgctt ttaaaagctt
    17461 ttcttctgga gcatttgcta gctcttcaat tgtaggaaac cattccatga aacgataaaa
    17521 ataatcgatc actgtgtcta ctctggtttg ctgaagcatg atctcagaga tccagatacg
    17581 ataaggatca cgattatagc gccaaggcag gtttcttttt tcttgttcat accattgaat
    17641 gaactgatct tgaaattctt ttgtttcttt atctgtccat ttttcccatt ctttattcac
    17701 tttcctcttc cttttccgta atgaatcgct ggatcatatc caaatcaaat cctttttgat
    17761 ataagctttg ctttactttt agatttcttt ttttaggttc aaaccttaaa tttcttcgcc
    17821 atagtttatc tccttgtttg actaaataat catattctat ttcttgatct gcttcttgcg
    17881 gaagatcagc tatcgcttgt tggatcactt cttgagaaaa gcctttcgtc atcaatgttt
    17941 gttggatttt tctcaataat tctttttggc tttttccgtg attttttcca aacgcttttt
    18001 cggctgtctg atgtgcattt tgaacttggt cttcaaatgt atattggctg agcgcttgtt
    18061 caatgatttc aggtttcaaa cctttttgct gcatctgctg cgctaatttc tttggtcctt
    18121 tgtcacttaa gcgcatattc gtgcgcacat aactttcccc atagaccaaa tcatcgacaa
    18181 ggtccaattc ttttaagcgg gctacgattt tatttcgatc ttcttgaagg atttcctttt
    18241 cttttaagta tgttcggatt tctttttccg atcgcaactg ataacttaag taattcattg
    18301 ctaggtgaaa accgaaatca gctccgctac tcttcttgat ctcttggata gtttcttcgt
    18361 ctaattcccg tccttttaat aatcgatagc gtactaatac atcttcagat acttgtaaag
    18421 cttctccttc agataaatct acgcgataga aagggccttt gcctttactg attctcgtaa
    18481 cggttaacat aaacatcctc ctcgaacata tattctctat cataccacag aaaatccccg
    18541 taatcaggta ttatatgtta gaataaacca cagaaaaaag aaaaagggag atacttatgg
    18601 cagaaacaat tgtcaaaact ggacaaacgg ttcctttgaa aatcaagcgt ttaggcataa
    18661 atggtgaagg aatcggttat ttcaaacggt tgatcatatt tgttccatat gcactaccaa
    18721 aagaagaagt actagtgaaa atcacgaaag caactcctcg ctatgcagaa ggagaattaa
    18781 taaaagtcaa aaaaacaagc aaagatcgcg tagtggcacc atgtcctgtt tactatgaat
    18841 gcggtggctg tcaattacaa cacttagctt atcaagctca attggatttt aaaaaggatc
    18901 tgcttttgca agcattggaa aaattcaaac cagcaggctt tcgatcttat caacttttgc
    18961 cgacgatcgg gatggatgag ccttggcatt atagaaacaa agcacaattt cagttacgaa
    19021 aaaataagca gactcaaaaa attgaagctg gtttatacga agcaaactct catcagttag
    19081 tccctataac agactgcttg gttcaagaac ctcgaacaca aaaagtaatg aatactgttg
    19141 ttcaactatt gaataaattt gatgcaccca tctatgatga acggacaaac agtggaatct
    19201 tccgcacaat catggttaga atcggtgtta aaactgggga gttacaagtt gtttttatta
    19261 ctcgcagtaa aaaattcccg caaaaaaacg caatgatccg tgagatcaat gaacgactgc
    19321 ccgaagttgt ttcaatcatg caaaatgtcc aggcacaaaa aacgtctctc gtgatggggg
    19381 atgaaacgat ccacttatgg ggaaaagaag ccattgaaga acaaatcaat gaagtgactt
    19441 tcgatctttc tcctcgtgcc ttctttcaac tcaatcctca gcagaccgaa ttgctttatg
    19501 gcgaaggaat caaagcatta gatgtccagc ctaatgaaac gatcgtggat gcttattgcg
    19561 gagttgggac gatcggctta agtgtagcaa aacaagccaa agaagtacgg ggaatggata
    19621 ccgttcctca agcaatcgct gatgcaaaaa aaaatgcgga aagattagga tatcacaaca
    19681 ctcgatatga agtcgggaca gcagagcaag ttctgcctaa atggttgaat gaaggttttc
    19741 agcctgatgg tatcatcgta gatccaccac gtacgggttt ggataacgca ttgatccaat
    19801 cattattgaa ataccctcca aaaaaacttg tttatatctc ctgtaatgtt tctacacttg
    19861 ccagagatct ggttaattta agtaaaaagt tcaagattga atatttacag tccgtcgaca
    19921 tgtttcctca gactgcacgt tgtgaagttg tcgtgaagat gacgagactc gctgactaaa
    19981 tgaaagaggt tgtgaaaaag tctgccctgt atcaagtaat aagaacagcc aaacaaaaat
    20041 agctcttcat gttttatgaa tactgtactt gtgaccgaag agttaacagg aggacactat
    20101 ttatttaaaa aaagggttgt gacatagttt ttgtcacagc cctttttgat tattattgga
    20161 tattcacgtc tatcacttga taaaatgcat ttgtcgtatc gctgatattc catactgcta
    20221 aaatcacatt atatcctttt cgatcctgcg gaagtgtgat cgtttggttg actgtttttg
    20281 gtggaacagt tgctttgtcg tctatttttg tgatcaattc aaaatcacta aatttcaaag
    20341 gttgattagg attccaagtt ggtttggtaa tgtagtaatc ccaagtactt gtccgatgtt
    20401 gtgctgttaa attccaagta atatttaatg ttcctggatt aaccatgttt ttatgccatc
    20461 tgttagatgt ctgttcatct aaaggctcaa agccgctgac tcctgcacta gcaatttttc
    20521 catcaatgaa tgtatttttg gtagcttcga tactttgcgg ttcccattgt gctcttccga
    20581 cattttgatt taagtttcct gctgctgatg ttcctaggta tgcacggctt cctggagaag
    20641 taatataacc atgcgcaaaa cctggaatgc taaaaccgaa caaccctaaa ctaactaacc
    20701 caataaacaa taacgtacta atctttttca tgtagaaacc tccttcattt gataaccaca
    20761 ttgtaaacgc tttattgtat taacacaaac attatgcttt tataatttta tgttgaagta
    20821 aaaaaggtga aaaaagtaag atgcagatta taacagaagt agacgagaaa agtacaaata
    20881 gaaaacatga gaatcaaatc atatgatctt tttcaaaaac atcattcata taaacaaatg
    20941 ttcaactttt taataacaac aattatcaat ttttttctta cttcacaaac taaatacagg
    21001 tcttgctgtg agccttcatg gtaaactaat attatagaaa ggagttagta aaatgaagat
    21061 gataaaagat attcgttttt gggtttgtgt tataggaatt gtcatattag gctttttatc
    21121 agggttgctt agcggaaatc ccggaaaata ttactattct ttgcaacttc caccatttgc
    21181 accacctagc tggatatttg ggccgatgtg gaccttactg tatatattga tgggtatttc
    21241 tctttatttg ttacttaatc acaacaacaa aaaacagcga aacaatcttg tcggtctttt
    21301 tgtgattcag ttcattttta attttatatg gtctgctcta ttttttaatt taagaaatat
    21361 tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc ttatgtatca
    21421 gttgtggctg catcatcgcc tggcaatgtg gctcatgatt ccttattatt tatgggtact
    21481 attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa aaagagacgt
    21541 cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc taatttaggt
    21601 ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc catactcatt
    21661 attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat aactttgagt
    21721 atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat aggtattcgg
    21781 atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt acccttcact
    21841 attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga acatcattga
    21901 agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta attgtttctt
    21961 cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt agatatcatt
    22021 gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg ccggggtgta
    22081 gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat tgttctcaac
    22141 tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt tattgacgat
    22201 tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg gatcttcgtg
    22261 tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac ctactggtac
    22321 atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac cgaccgcatt
    22381 gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag gaatatcgag
    22441 cagttgctca attgaatcca tggccatttc gacaccacca aatgcgtagg catgatttaa
    22501 tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca aactgatgat
    22561 cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag aacgtccttg
    22621 ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa aaggttcttt
    22681 gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt ttttagaaat
    22741 tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg ataatccggc
    22801 aatcagcaaa acgaataccc ctaacaaggt taatagaact ttttgccatc gcttcataat
    22861 acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat cagcaaattc
    22921 actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattat tattttttaa
    22981 aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa gaccgaatac
    23041 acgcagttcg caatcgtttt atcttttttt atgtattttt tccagaaaaa gcgaacaaca
    23101 aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc atctttttaa
    23161 cagtctttgc ctaccgttca gattatcatt cgatttcacg acaatttctt cctatgactg
    23221 gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca tggctcttaa
    23281 aatgactcga actagtgatt gcattaccat catcttttaa tggatagata tgctcctctt
    23341 caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag tatgtatact
    23401 agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct ttaaaatcca
    23461 ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca agtgaacaaa
    23521 tgcatttact tagccaaaaa atctaaaaac ttcataaata gacaaaaaga cacgactctc
    23581 taagaagtcg tgtctttatt caacaaatta ttataattta gtcacttcag cagcttgagg
    23641 tccgcgtgca ccttcaacaa tcgtgaattc tacttcttga ccttcttcta ggctcttgaa
    23701 gccgtctcct tgaattgctg agaaatgaac aaatacgtca tctccgccgt ctactgtaat
    23761 aaacccaaat cctttttcat tgttgaacca tttaaccgtt ccgtgttcca taaatgtata
    23821 tcctccaaaa aagttcttgc aagtaacctt gcaagaacat tatacccaat ttagaaaacg
    23881 ctagcaagct ttcgctcttt tattttccaa attattttta agactgatat gacggaggaa
    23941 atggttattt tgctgcttcg aaacgtttgt ttacttcatc ccaattaata acattccaga
    24001 atgctgcaat ataatctggt cggacatttt tatatttcaa ataataagca tgttcccaaa
    24061 cgtccaaacc tagaattggt gtctttcctt ccatcaatgg agaatcttga tttgcagtag
    24121 aggtaatagc taattttcca ttttccatta caagccaagc ccatccagaa ccaaatcgtc
    24181 cagcggctgc ttttttgaat tcttctttaa aagaagaaaa atcaccaaaa gcttcattaa
    24241 tcgcttcttt tatttctcct gtaggttcgc caccagcatt tggtgccatg atttcccaga
    24301 aaaatgaatg gttagcatgt ccgccaccat tgttacgtac agctgtcttg atatctgttg
    24361 gaatagcgtc catatcagat aataattctt ctattgtttt ttcgcctaat tctgggtatt
    24421 tctcaattgc tgaatttaaa ttcgtcacat aagtattgtg atgcttatca tgatgcagat
    24481 gcatcgtttc ttcgtcaata taaggttcca atgcgtcata tgcataaggt agatctggta
    24541 atgtgtaagt cataaaaaaa ttcctcctca atgttttctt aataatgtct acattacaaa
    24601 gagtaacaaa gagaaggaaa ttcttcaatt gttatgccta gtcgtctttt tcactttgac
    24661 ctacttcttc ttcaaaaacc tcagtttctt taaaaataaa caacttgctg aaaatatagt
    24721 tcgcaaggat aacaataatt tgagtgatga ttttcgccac atactcattg ctgttcataa
    24781 cattgatcaa caataccatt gcccccatgt ccaatccgta agaaaggata cggtagaaga
    24841 agaacttacc gcattcaata agtgcatgtg taaaattcgg tgattttgaa tggaataccc
    24901 aaagtttgtt cgttacaaaa gcaaacaata cagaacaaaa ccacgaaata gaattggata
    24961 aggccatact taaatcaaaa tattggcgtg cgagagcaaa actaacaaaa tttacaatcg
    25021 tagccaaacc accaaaaaag agatagacta gtatctccca atatcctttt gcttctaaat
    25081 atccttttaa ctgtcgatac tgcttcatga gccaacctac cttattaaaa attcttattt
    25141 atcatactct atatttcaat aactttcatc tttatttaaa aaaattaatt ttttttgatc
    25201 ctttgccttt gtctctgctt ggatcgtcac atgtgtaata ccatatttta attttaataa
    25261 agaaattata cgaggatata tcttttcaat ctcgcttagt agctgatctt caaaatcaat
    25321 atgtccgtcg aaaataatta tcttttcgct atactgccaa atatggacat gatgaacatc
    25381 ctttacccca tcgattgctt caatttcttg ttccattttt tcatagtcga tagcaggtgc
    25441 actttgtatc aaaatagcgg cagctttttt gatcaccatt atcgcttcta tcaatatata
    25501 tatcgaaatg atcagtgtaa taactggatc gatccagtag atatcgaaaa aacggatcaa
    25561 aattgctccg ataatcacac ttaccgaaga cagtgtatca cttaacaaat gcaaataact
    25621 agattttata ttcaaacttt catctgcttc ttgtcgtaat aataatactg agaacaaatt
    25681 cgcgagcaat ccaataactg ctactgttag catcaaatga ctatttatct tttctggtga
    25741 agtgaaccgc ttgaatgctt caacggttaa aaacaaggat aatatgatca atatgaatga
    25801 gttgatgaaa gcactcaata tttctaaacg ctggtagcca tacgtacgtt ttttatttgc
    25861 ttcttttcgg gccatttttt gtgccccgta agaaaaaata attgccaatg tatcactaag
    25921 gttatggaaa gcatctgaaa caagagacaa actccctgac ataatccctc caataaattc
    25981 tgataaagtg atcaccgcat tcaaaaccac tactccaaat agtttttttg atgatctctg
    26041 tggctgtgta ggcactattc cttcctccat tttatttata ttggatagtc tttagacaag
    26101 aataacattt ttttgatatt tcaccaatca ttcagctgtt tccttaaagc acttgtattt
    26161 cacttgatac ttcgctagaa ttgcaagtga tgacactact agatgaggag tacttatgac
    26221 aacaaaacaa ttaattatca gttcctttat acgattcaaa gacctaaagg aggcgagaaa
    26281 tgtcccattt tggaaagcca ttgtctatct tttagttttg agtataatta tggctttgcc
    26341 aatctctttt caagtttttc aagtcttaaa caacattcaa ttggatgggc aaaagattgc
    26401 tactcgcatt cctgatttta caatccaaaa cgggcagctt caaaccgaag aaaaagaagg
    26461 attcatttac caaacaaact ccattatctt cacatttgat ccagagggaa aacgaacaga
    26521 acaggacatc tctactgatt tgatggggaa ttttgttagt gtcgggatgt taaaaaacaa
    26581 acttatcata gctcttccta atacaggcac gacttctgct ttgttgaaca ataaccaatt
    26641 agaacttccc tacaccaatg aatctttaaa aaacttaaca ggtaagcagc tccgttcttt
    26701 tttaagtgaa gcatctatac cactttggat aaaagtcctg acatttatat tttctattta
    26761 tcctagtttt ctgaatctgc tgatcacttt gctatttacc aacattgctg cttttctcta
    26821 tgcacgcttt cgactaacaa aagctacttt tcttgattgt ttaaaaacat tgatctattc
    26881 aatttcattg cctactataa ttgcaacaat cttgatggtc tttcttcctt cttttgacac
    26941 tagcgccttc attgcttttg caggaatctt tatttttgct caagctgtca aaggatgggc
    27001 aaaaatatcg atcaattaag aaataaagac aactcgttat ttctacttca atagaccctt
    27061 ttagaggttg tgacattttt ttgtcacagc ccctttttta tttgaaaaat atttctttct
    27121 caaaaaacaa gcaaggcgct tcaaagttct tcttgtatgc gctacactta gagtaaagaa
    27181 aggcgggaaa ttaactatgt cagaaagaat catttatgca gatcgtccat ttcgtgatga
    27241 atttatcgaa gaaatccata ctatagcgcc tggttatatc tttaaaacag aattacaacc
    27301 agaggatcta caaaatgtag agatcagttt gggctggaac tcagactacc aagaaaaact
    27361 attagcctct tctaccttga aatgggtcca atctatctca gctggtgttg atcagctacc
    27421 ccttgagact ttttcaaaga aacatatttt actttcaaat ggtagtggca tccacagtga
    27481 atcgattacg gagcatgtct taggaatcat ccttgggtat tctcgtggtc tttttcaagc
    27541 acaaaaggca cagagtgaca tgaaatggtt aggttcatcg gtccattacc aatctatcca
    27601 agggaaaaaa atactaatca ttggaactgg ccatattgga aaaatgattg caaaaaaatg
    27661 caaagcatta gacatgaact gctatggaat caatacatcc ggtcatccag cagaaggaat
    27721 ggaaaagact ttttctttaa atcaactaaa ggaagttctt cctgaagtag atttcgtagt
    27781 caatatctta cctctaacgg aggaaacaac tgggctcttt gatcagcata tgtttgaaca
    27841 ctttgatcca aaatctgtat tcatcaatgt tggccgtggt gcttctgtta agacacaaga
    27901 tctggtgcag gctttaaata accagcaact ttcctttgca gcattagacg tttttgagga
    27961 agagcctctt ccacaagatc atcctctttg gaaaatggac aatgtactga ttacttccca
    28021 cattgcaggt ttgacacctg attttcaaaa gaaattaatg gctatttttt taaccaatct
    28081 gaaaagctac tttgccaccc atgagcttca aaccaatcaa gtaaaattgt ctgcaggata
    28141 ttaatagctg aaaacaatat tttcaaaaga aaaaagagaa ggtgacaaaa attgtgtcac
    28201 cctctctttt tttattgttt tttaaagtga taggttggct cctccaggtt gggatcataa
    28261 tcaacaagta aatcatatcc tttaaagaac cattcatctg cttcctcgat aaaaaaaagt
    28321 gtcccatcaa tttccacttt ctttacagga tgttctggct gttcaactga cattccaatc
    28381 gaaaaaccat catgaacctc tgttttgccg tagacttttc caaaaaaacg tattccgtaa
    28441 gtttctggca gatcaatttc tgagtcaaac cacttttgtg cttttggcgt taccgttaat
    28501 ttcatcccaa caacctactt tctcttttct ttctattgat tcatcttatc gtctagaata
    28561 tccacatcgc ctgtctctcc aataaccagt agattatcat tttcacgaac atattcatct
    28621 gctgcaggag aagcgataac cgtttgatct actcttcgta tggcgactac tgttaagtca
    28681 aaacgttgcc tgaaatttaa ttcagctaat gttttgttga aaaatttagg attggagact
    28741 cggatttctg ctaaagaata tttatctgac aactctaggt aatctaaaat attctttgac
    28801 actaaattat gcgcaatcct tattcccatg tctcgctcgg gatggacgac gcgatcagct
    28861 ccgatctttt caagtactct ggcatgatac tcattttggg cttttgctaa aatatttggt
    28921 acgcccattt cctttaccat cagagtaact aagatactgg cttgaatatc ttctccaata
    28981 gcgacaatta catgatcgaa atttcttatg cctaatgatc gaagtgtcat ttcatcctgt
    29041 gcatttgcca caacagcatg agtggctata ttcatatatt cattgacccg atcttcatta
    29101 ctatcaatag ccagtacttc ttgaccagct tcgatcagtg ttcggcagat acttccgcca
    29161 aatcgtccaa gacctacaat tgcaaaattt tgtttcaccg ttttcctcct ttagtatctt
    29221 cttttctcag tataacaaag cctttacaaa aacaaaagca agcatcatta ttgtaaaaaa
    29281 gccaagaaaa ataatagtta ttttctcagc ttttgattat cctctttatc atcgttttta
    29341 tttcaccaaa ccatgtttga atgcatagat agcggcttgt gtacggtctt ccacttctag
    29401 cttagccaat atattggaaa catgtgtttt tactgttttc agtgtaataa acaattcgtc
    29461 cgctatttcc tgattacttt ttccttcaga aatcagcatt aaaatttcat tttcccgatt
    29521 cgttagttct tcatgtaata caggctcatt tcgccgactc attttttcca tcatttttgt
    29581 tgtcacttct ggttctaata ctcgctcgcc acgttgcgtt gcccttatag catcagcaat
    29641 ttcatgtgcg gtagaggtct tcaacaaata ccctgctgca cctgcttcaa tggcaggata
    29701 aactttttcg tcatcaataa aactggttac gataatgatt ttagcttctg gccaatcttt
    29761 taagattgct tttgttgatt cgataccatc catttcttcc atgactaagt ccattaaaat
    29821 gacgtccggt cgaagtgtca tcgccttctc atagccttgt cgtccatttt cagcttctcc
    29881 aattacttca atgtcttctt gaatagataa ataaaaagag acgcctaagc gcaccatttc
    29941 atggtcatct actaataaaa cttttatcat ccttatctat gcctccttca tcaaagggac
    30001 cttgatttct acacttgtac cttgaccttt aaaactaatg atttttactg ttccaccaat
    30061 accagctact cgttctttga tattgttcaa tccataactt cccgttttcg tttcattcat
    30121 attaaaccct gttccgtcgt caataatacg taacaaaaga ttattgtcta ttttgtgcaa
    30181 atatacctct aattcattgg ctttagcatg tcttaatgta tttgataaca attcttgaac
    30241 gattcggaac aagtgatcct caatggaact agatagtttt acatcttcta catcccattt
    30301 cagcgaaatc tggattttat tttgcaattc cttcaataac tgctcgatac cttgctttaa
    30361 acttttctct tctaaattga ctggacgtag atgaagaagc agcgcacgca tctcagactg
    30421 ggaagcgttg atgatctctg ctaccatttt caactgcttg cgaaacattt ctggtgtctc
    30481 gcttttttct gcttgctccg tcaatgccga catcatcatc attgctgcaa acaattgttg
    30541 cgaaactgaa tcatgcagct cacgggctaa tcgatgtctt tctaattcta aaatttcttc
    30601 tttggtttgt ccatctacat attggggacg gctcgttaca atttgtaatt cactagatac
    30661 ttcaatcatt ttttctttta tcttagtgat ttccttatca atatctttga tgtataaatc
    30721 gtccgatgca cttgggatcg gaagaagcaa caatttggat tcataattgc cagaagaaag
    30781 tgcacgcagc ttttcttcga ttttcccgta ttttgtcttt tgaataagtg ataataatag
    30841 aaagacaatt aatcctacac ctaaggaaat ggctaacaaa tggaagataa gcggaacata
    30901 taataaacgt gcacgcagta attctcccca ccaatgactt tgattgctgg cataaaaata
    30961 agtgaaaagt gaaaatagaa taataaggaa agccgcaatc cccgaataaa cagctagcat
    31021 cgctctggat atttttccca tcatattcgt atcacctcga catctccaat caaggtatta
    31081 gtaataatct tcaatctacg agggttttca tcataatcac tgctgtagat tttgatttgt
    31141 tcatttttca aagaaaattg ctcttcttca aacaagacat ttcctactaa tgtcgcatgc
    31201 tctaatcgga tggctacgcc caaaggtact aagatccgtg ttctgcctat cccttttctt
    31261 acaatcacaa tattatcatc ttttggcaaa agcgtattgc ccaaatctat gatagtatca
    31321 ccagaaatga cggcgatgtt gatatcgtcc cattcataga cgtcgtttcc aatacgttgg
    31381 ttaccgaata attgctgtct tttccgctca ttattatgtg tttttaattg ctctgtttgg
    31441 atcatcatga tctgtttctt tcgccaaaaa gcatttttgg ttaaatctat ccctgaaatc
    31501 tctacacctt tcagaccaat aaataaaacg gcaaatacag ccatcatcca taaagcagga
    31561 ctgttgacta agctaaaaaa aatgaccaaa cttcctaata tcaattgaaa attttgaaat
    31621 ttagtacgag gatgtttgcg catagctaga tatatattga aaataccgaa tatcactaaa
    31681 agcaaaagtc cagtattgtt tacgatttgc caaacagcaa ataacagcag tagtgcttca
    31741 actaccacaa aaaaacgcca agaactattc atcgctcttt ctccctcctg acacattctc
    31801 atttcatcat acctattttt ttaactgttg gctataggac tttagatgta agatcgtttg
    31861 ttgaaatcta aaatacacaa agagaaaaag atctagagtg tatcatcagt aagatgaact
    31921 ctctagatct ttcagtcaga ctacgcttgt tctactttga cgattttaac taacatatcg
    31981 ccacctggag tagcaatagt tacttcatca tttttacgtt tgccaatcaa tgcttgcgca
    32041 ataggagaat cattggaaat tttgccagaa aacggatctg cttcagcgct tccgacaatc
    32101 gtgtactctt cttcttctcc atctggtagt tcgatgaatg taactgtttt accaattgat
    32161 acctcatctg catctacacc gtcgttatcg atgatttgag caaaacgaat catattttca
    32221 attgttgtga ttcttccttc aacaaatgct tgttcatctt tcgctgattc atattcagag
    32281 ttttcggaaa gatctccgaa accgcgggca attttgattc gttcaatgat ttctccgcgt
    32341 ttgactgttt ttagttcttc taattctttt tctaattttt ctttaccttc tagagtcatt
    32401 ggataaactt tctctaccat gtgtaacgtc tccttttttc gataaaatac cgcaaaaggt
    32461 aatcttttga ggaatatagt ccaaaaaaga ttaccacgct tttcttcaaa tgtaaatgtt
    32521 tttctaaaaa tgatcaatgt ctagagcctg tttttctaag aattatttac atatttttcc
    32581 actaattcca tatgttcttc ataagtttta gcgaaataaa catttccagt gctcgtatct
    32641 gctacgaaat aataatagtc attttctgct ggttctaata ctgccttgat tgcctcttcg
    32701 cttggattgt caaaaggtcc aggtccatag ccggtattgg tatacaaatt atatggtgaa
    32761 tctacagctg tatcttcata cgtcactaat tctttgtgtt cacctaatgc gtataaaaca
    32821 gagatatctg actgaagtgg catatttgct ttgattcggt taaagaagac ttgtgcaatg
    32881 tttttacgat cattttcttt tacgccttct ttttcaacta gagaagctag agttaaaact
    32941 tcttgtacag tcaaattttt ctgcttgata gctgaataat agttttgcat gaccgtattc
    33001 gtcttgttca ccatttcaat cactagatcc ttaagcgaag tactcgtgta ataatcatat
    33061 gtggctggga ataagtaacc ttccaaacgg tattttgtgt tctcagcttt agatgcactt
    33121 tccaacagtt ctgggaattt ttggtgcaac tcgttaaaga aagtctcatc attcactaaa
    33181 tctaaaaatt ctttcttgtc tttaccagtt accttcgcta cccgttcagc aatctgatcg
    33241 atatcgtacc cttctggaat ggcaattttc ccatctgcaa cttttgttgg ctcagaagta
    33301 ccgccttctt gcaactgttt gccaatctcg tcaagagtca tattaggcgc taactgataa
    33361 tagccagctt gaaagccagt taaattttta aattttgtat aataattgaa aacaatcccg
    33421 cttttaataa tattgtcctt ctccaaaatc tcaccaatct gcttgttaga agagccactc
    33481 gggatctcga cttggactaa ttggtcatct gatttatcta aaggcttcaa cccgctatct
    33541 acataacgat acacggtaaa tccaagaaat ccgccaataa tcaataatgt aagagcaatc
    33601 actaaaatga tcttcctcac aatcttatct tcttttttac gcagatttct ccgcttgtcg
    33661 attatatctg ctgtagctgc cttactggct tcttttttat ctttacttgg gtgttgtttg
    33721 tttcctgaca aaacaactcc tccttactat caagttcgta actttattca ttatacatga
    33781 tatttgaatt ggcgtgaatg attttattta aatattctat c
//
LOCUS       DAZKPE010000026        33817 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000026 DAZKPE010000000
VERSION     DAZKPE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.026"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..120)
                     /locus_tag="ACG930_001363"
     CDS             complement(1..120)
                     /locus_tag="ACG930_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFQ0518531.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            299..1960
                     /locus_tag="ACG930_001364"
     CDS             299..1960
                     /locus_tag="ACG930_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0518532.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="ACG930_001365"
     CDS             complement(2030..2377)
                     /locus_tag="ACG930_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFQ0518533.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /gene="opp3b"
                     /locus_tag="ACG930_001366"
     CDS             2461..3402
                     /gene="opp3b"
                     /locus_tag="ACG930_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFQ0518534.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="ACG930_001367"
     CDS             3403..4446
                     /locus_tag="ACG930_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518535.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="ACG930_001368"
     CDS             4452..5522
                     /locus_tag="ACG930_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518536.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="ACG930_001369"
     CDS             5512..6465
                     /locus_tag="ACG930_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518537.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="ACG930_001370"
     CDS             6477..7487
                     /locus_tag="ACG930_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFQ0518538.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="ACG930_001371"
     CDS             complement(7772..8593)
                     /locus_tag="ACG930_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFQ0518539.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="ACG930_001372"
     CDS             complement(8690..8968)
                     /locus_tag="ACG930_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518540.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="ACG930_001373"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="ACG930_001373"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFQ0518541.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="ACG930_001374"
     CDS             complement(11724..12311)
                     /locus_tag="ACG930_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518542.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="ACG930_001375"
     CDS             12486..13808
                     /locus_tag="ACG930_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0518543.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="ACG930_001376"
     CDS             13963..14739
                     /locus_tag="ACG930_001376"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFQ0518544.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="ACG930_001377"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="ACG930_001377"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFQ0518545.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="ACG930_001378"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="ACG930_001378"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFQ0518546.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="ACG930_001379"
     CDS             16629..17258
                     /locus_tag="ACG930_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518547.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /locus_tag="ACG930_001380"
     CDS             complement(17382..18491)
                     /locus_tag="ACG930_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518548.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="ACG930_001381"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="ACG930_001381"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFQ0518549.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19309..19407
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19445..19981
                     /locus_tag="ACG930_001382"
     CDS             19445..19981
                     /locus_tag="ACG930_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFQ0518550.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20021..21784)
                     /locus_tag="ACG930_001383"
     CDS             complement(20021..21784)
                     /locus_tag="ACG930_001383"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518551.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21787..23502)
                     /locus_tag="ACG930_001384"
     CDS             complement(21787..23502)
                     /locus_tag="ACG930_001384"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518552.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24281..24505)
                     /locus_tag="ACG930_001385"
     CDS             complement(24281..24505)
                     /locus_tag="ACG930_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518553.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24696..27473
                     /locus_tag="ACG930_001386"
     CDS             24696..27473
                     /locus_tag="ACG930_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0518554.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27554..27973
                     /locus_tag="ACG930_001387"
     CDS             27554..27973
                     /locus_tag="ACG930_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0518555.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27985..28455
                     /locus_tag="ACG930_001388"
     CDS             27985..28455
                     /locus_tag="ACG930_001388"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0518556.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28472..29251
                     /locus_tag="ACG930_001389"
     CDS             28472..29251
                     /locus_tag="ACG930_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0518557.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29238..30059
                     /locus_tag="ACG930_001390"
     CDS             29238..30059
                     /locus_tag="ACG930_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0518558.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30076..31125
                     /locus_tag="ACG930_001391"
     CDS             30076..31125
                     /locus_tag="ACG930_001391"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0518559.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31138..32142
                     /locus_tag="ACG930_001392"
     CDS             31138..32142
                     /locus_tag="ACG930_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0518560.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32775..33794
                     /locus_tag="ACG930_001393"
     CDS             32775..33794
                     /locus_tag="ACG930_001393"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFQ0518561.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        11041 a         5991 c         6908 g         9877 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata
    19981 aaaaacaagc agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg
    20041 cttgatagag ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt
    20101 cgacaatagc tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc
    20161 gatgggcaat cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt
    20221 ttttctctgt caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat
    20281 tactgatcat cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc
    20341 cttgaccgcc aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat
    20401 aagaggcttt tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa
    20461 gattttctcg caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt
    20521 tacgtaatgt atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt
    20581 ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt
    20641 ttcctactat agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac
    20701 gctgcttggg gtcataagaa aaagaaacat gatcaaaaga gacttttcct ttgatatttt
    20761 tgggttccaa ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat
    20821 caaatgctcg ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt
    20881 cgataaatgg tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag
    20941 tgattgacga accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag
    21001 caaggtgatc tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt
    21061 gtcctttttc atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt
    21121 gctgaaaagc tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat
    21181 ccccaataat cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac
    21241 tcacaaggaa aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac
    21301 gcatcataaa aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg
    21361 ccgcagaaat tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc
    21421 cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt
    21481 ttcttaattt tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt
    21541 gactgactac gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat
    21601 tgaagcggac ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca
    21661 tcacaactgt tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg
    21721 cataggcagt aaggtaagga atgaatcggc ggagcgtctg caaggataat ttttttactt
    21781 tcataactat tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag
    21841 taattcttca tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg
    21901 tgcttcttga atagagcgga cacgttggga gataataatc actgtactgc caagataagt
    21961 ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc
    22021 taaaatcagt aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg
    22081 tccgccagag aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg
    22141 acggacaaat tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc
    22201 gtctttctta ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg
    22261 gggaacaaga gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc
    22321 gtccattata actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt
    22381 cgttttcccg cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa
    22441 tgtaatattt tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa
    22501 agcgataatt gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga
    22561 attttctgtg tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat
    22621 cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa
    22681 agcaagaact tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag
    22741 caaacagatg atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat
    22801 attggaaaca cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt
    22861 ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac
    22921 gtgttcattg agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt
    22981 gatgataaaa aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac
    23041 ttcccagtcg atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat
    23101 caataaacga atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg
    23161 ggtgatcaag gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt
    23221 tttgattagc tgattacgta actctgtacc aaatccttgt gaagctactg aagcatagta
    23281 ttggcaaatg atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat
    23341 ttcaatgatt tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat
    23401 taaaggcagg acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat
    23461 ttgcttacga tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt
    23521 tatttgtcca caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg
    23581 aaaagagaac aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga
    23641 atagactatt ttttttaaaa aaaagaaaat gagaaaacat gccagtctct tcattcatag
    23701 gaacgtctat tttacttaat ttttctataa atgaattctg cataaaaaat atatcaagta
    23761 aatgtttata gatgaaactc tatttacttc ttttttaatt tgttcttgca atcttttttg
    23821 ctacgtaatt tttgtaaaaa agtgggttga gagaaatcta attgattttc aaagaaggag
    23881 tatgaaaatg agaaaaatat ttattcgttt attgtgggta ctatcttaga ggaataaata
    23941 atagtggaga aaactatggt ttggcgcaga ttctatcagg tttgatggaa cgaagacaac
    24001 ctcccgacat caagtcaaaa gctacttgag attttgatct gaaaataaaa aaagaaaaca
    24061 aggtaggaac atcaatgttt ctaccttgtt ttcgtaatca atgggaaaaa actaagagtg
    24121 gtgtacgtaa tcaataaaaa ggatggtgac aacagtacct ctttactctc tgaaagcatc
    24181 ataactcgtt tttcctcatt atgccaataa attgttgtta taccacatat aaggatttgt
    24241 aatagctaaa aacagacagg aaagttgaaa tctgtgaatc ttattttgta tggaaggatt
    24301 tatagaacgc aaaaatcaag ataaagatga ataaaaatcc tgtttcggct atatattgcg
    24361 tatctacgcc aataaaacga gtttgttctg tcatagccat ataaagcaaa ggcaaaaata
    24421 caactacagc gagataagat ccgatgattt ctcgaaaagt tttccaggaa gtatgtttcc
    24481 tgtttttata tttatccgat ttcattgaat agtcatagcc tccttattct ttcatatgtt
    24541 gaaattccag tataaaaact ggaaggaact gtacgttttt tagaataaaa attataaggg
    24601 ataagtaggc tgctgtctat aataagatat atttttcaat tctttattaa agattttatt
    24661 gacaaaatga atccgttttc tatgatggag gaggggtgaa taagttgttg aagaaggaaa
    24721 ttttatgtta cttagagaac cagacagcct ttttcgattt agaacatatg aacgaggtct
    24781 ttacagcaca aaggttagct gatcattttg gggtaaaaag aaacacagtc agtcattatt
    24841 tgaaccagtt aaatgatgag caactactag tcaaaatcaa ttctcgacca gtgatttatt
    24901 tccacaaaga agcttttgaa aaacaatttt ttaagttacg cacgaatttt tatttttcta
    24961 tcgatgatct caaagaggaa cagccttttt tcgcgcaacc aaaagactta ttctctttta
    25021 tgatcggata cgacgccagt ttgaaagaaa gtatcgaaca aatcaaaaca gctctttact
    25081 atccagatgg cggattacca cttttgatta caggcgaaag tggcacaggt aaaagttatt
    25141 tagttaattt ggtctatcag tattgtctgc ttcatgatct gctagaagat tctgcaccat
    25201 tcatcacttt taattgtgca caatatgcag ataatcctga acttttgact agcaatttgt
    25261 ttggacatgt taagggagcg tacactggtg cagaagaaaa taaaaaaggg gcttttgaag
    25321 cagcagatgg tgggatcttg tttttagacg aggtacatcg cttaacacca gaaggtcagg
    25381 aaaaactgtt cacctatctt gatcaaggtg tgatttatcg tatgggagaa cctaatttgt
    25441 cacgccggat caaaacacgt ctcttttttg ctacgactga agagattact agtcatttct
    25501 taacaacttt cattcgaaga atacctatcc gaatcgaact acctgcactt aatcagcgta
    25561 gtcgtaatga acggctagaa ctgatttact ctttttttct cgaagaacaa agaaaaatgg
    25621 ggagcccttt gtcagtcagt ggaccagctt tgtcactttt aacaagtcag aaattatccg
    25681 gaaacatagg agagctgaaa aatatcgtca aagtttcagc agcaaaagca tatgctgaac
    25741 agcgtgaaca gcctgaaatc catgtcacga tccatcattt gcaaaaagaa ctacttgcgc
    25801 agcctattac taaaaataca gcacagcaag gaatctatat tacgcaagac cagaccttag
    25861 agcaattaat ggagaagcaa cagcccgaac agcagcgaat cgttaaaagt tttgagcaaa
    25921 tcctaattga tttcaagaaa aataactgtc tgctatattc ttgcgaagga aaattaaagc
    25981 aagaagtgat tcaattattt gattttttgc tgtttgagac cagtagacaa gaaaaacacg
    26041 agctgctggt ttattggaca caatctatcc gagagacctt tcgacaaatg gaaactgcct
    26101 atcaaatcaa attcgatgga aacagtgtct atgccttgag ttactatctc tatcagcgaa
    26161 gcactatcaa atggttaccg gaagaacatg atattatcca actaatcaaa gaattagaac
    26221 aacaagtttc tcagtcttat ccatctagtt atcactatgt ccaacgaatt ctggaattaa
    26281 gtaagatcaa attagatatt gaagacacaa gtatggatcg gattttactg acgatctatc
    26341 taaaaaaagc gaaatggtca aaagaaaaac gactgccaaa agcgatgatt gctgctcacg
    26401 gttatgcaac tgctagcagt atggcaaatg tagtaaatcg tttattacaa gaggatctat
    26461 ttgaatcatt tgatatgcca ctagatgtca caccacagca gattgcttca gaaatccttg
    26521 attattgcga aaacagcgat gtttcaaatg gattgatcat attagtagac atgggatctc
    26581 tgaaagaaat ccatcagttt tttaaaaaac agttatccgt accgcttttg attttgaata
    26641 atgtgacgac acctttagca atcacagtag gggaatgcct gcaaaaaaat gtatcattag
    26701 aagagatagc agaagagact gttcgacaga tccagccaga atggcgactg ctctatccag
    26761 aggaaaacaa acccaaagca ctcattacta cttgcttcac tggaatcggt acggcggtcc
    26821 acttaagtga actgctagaa aaaagcttac ctacggcttg tcagttgaaa atcatcccat
    26881 atgaatatca gcaattaaaa gataagaaaa acagtgaccc attattttcc atatacgaag
    26941 tcgtaggaat gattggcacc acagatcctg atatcaccaa tatcgactat ctttcattag
    27001 aagacctcat ctcgggggaa aagatgtctg tactagctga atggttggac actactatga
    27061 atgcttcaga gaaggaaata ttcaatcagc gcatcattcg taatttttca ttggaaaaag
    27121 tactggattc cgtgactatt ctagatacag agaaggtgat gggagaaatc gatcatttta
    27181 tgagagaatt agaggtgcag ttgaatcgaa gcatcagcaa tcccaaaaaa ttagcgttgt
    27241 atgtccatgt gagctgtctc attgaacgat tgatccgaca aatgccaatc gaaacctatc
    27301 aaggattaga gaaatggaag cagtgtcaaa aagaagggtt atctgctatt aaatctgcgt
    27361 ttagtgtcat tgaagagcat tatagtgtca tgatccccaa ttctgagatt gcctatatct
    27421 atgatatttt gagtgaagat acagagtttc tctcgataga agaagaattt tgaacataag
    27481 caagttgttg ccactaattt tggcatgcaa cttgcttttt tagtatgtgt aagtgaaaag
    27541 aggagatgaa aaagtggata gagaaattat cttagcttcc catggaaaat ttgcttcagg
    27601 gatattagat tcattagagc tgatctatgg gaaaaatcat tctattactg tattcgattg
    27661 ctatactgat gagaattttg atttagcgga aacagtaagg cagcttttta tgaggtacaa
    27721 agataaagaa atcattgttc tgacggatct ttttggcgga agtgtcaaca acgaattctt
    27781 acaatatatc aatcgggatc atgtctatct cgttgccgga ttgaatttgc cactattgat
    27841 tgagctagta tctcggttgg acgctgaagt agagacaact gttttgatcc agcaggtgct
    27901 aactgattca aaaaaaatga tccagttttg taacgagcgg ctcaatcaga aaatagaaga
    27961 agacgaattt taggaggaag aaaaatgatt gtattgacaa gagtcgacca tcggttatta
    28021 cacggacaag tagctttttc atggacacaa acaataggcg cagactgtat tttgattgct
    28081 aatgatgatg tacctacgaa tgagatacga aagacaacga tcaaattagc caagccacaa
    28141 ggagtcaaac tagtgatcaa atcaattgat gactcgattg ccgcgttgaa aagcggggtg
    28201 acagataaat ataagttatt catcgtagtg gaatcgatcg aggatgcata taagctggca
    28261 gaagcgtatc cagaaatcaa aaccatcaac ttaggaggga tcaaggcaaa acctggtact
    28321 cgcagcatcg gaaaagcggt aaatatttta ccagaagagg aggaacgctt gaaacgatta
    28381 attgacaaac aaatagaagt agaaatccgt caagtaccag cagataaaaa agtggatgta
    28441 agagaagttt tgtaagaaag gaagaacctc aatgattgta caagcagtct tattaggaat
    28501 tgttgcattt gtcgcacaat cagaatatgc actagggaca tcgttgcttt ctcgtccgat
    28561 tgtgacgggg ctgtttacag gaatcgtgtt aggtgatgta aaaactggga tcattatggg
    28621 cgcaacttta gagttagcat ttatcggatc gttctcagta ggtgcttcga ttccacctga
    28681 tgttgtgacc ggtgggattt tagggacggc ttttgctatt acagctggag ccggtacaga
    28741 aaccgcgctt ttactaggtt tgccgattgc tacgttgaca ttgatattga aaaatattta
    28801 cttagggctt ttgattccaa ttatgaacca taaagcagac aattatgcag aagaaggaaa
    28861 ttataaagga gtcgagcata tgcacttgct tgccggtatc ggtctttcct tgatgcttgg
    28921 tgttgtggta atggtttctt atatggtggg aagcaatacg atcggaaatc tattaaatat
    28981 gattcctgac ttcgttcaaa aggggttgtc agtagctaca gggttgattc cagctcttgg
    29041 ttttgcgatg cttgctcgtt tgctgatcaa caaacaagtt gcaccatatt ttttcttagg
    29101 ttttgctata gcttcttact tagagattcc tgtgaccgga gtagctattt ttggtgcgat
    29161 tttagcagtt gtggtagtca atattatgaa tgtccgtcaa ctaccacttc aaacaactgc
    29221 aggggaggta gaagaagatg aagaattctg agatcaaaaa cagcaaaata acgaaaaaag
    29281 agctaaatca cgtattttgg cgttcttttc aaatggagtt ttcttggaat tatgaacgtc
    29341 agatgaatat ggcttatgtt tatgcaatga ttccgatttt gaaaaagtta tatcagtcga
    29401 aagaagaaat ggcagcagct ttgaaacggc atctagagtt ttttaacacg accccacata
    29461 tcgttacact gattttagga atcacggctg caatggagga agaaaataag gatgatcctg
    29521 aatttgatgt gactgcgatc gatagtatca aaacatcttt gatgggacct cttgcagggt
    29581 taggagattc tttcttttgg ggaactttgc gattgattgc cacaggtgtg ggtacctctt
    29641 tagccatgca aggaaatatt ttaggcccta tcttgttcat tttgattttc aatattccgc
    29701 acattctgtt tcgctatcta gcaacaggtt ggggatatcg cttaggaacg ggttttttga
    29761 aaaagatcca ggcaaacggt atgatggaaa gtttgacatt aggcgcgtct attattggac
    29821 tgatggtcgt tggagcaatg actgccacga tgatcaccat caatattcct ttaaaaatcg
    29881 gttcaggaga aaatgctgtg actgttcaaa gtatttttga tgatatcgtt ccaaatatct
    29941 tatgtcttgg agcatttggc atagtgtttt atctattgaa gaaagaagtg aaaccattaa
    30001 cgatcttgat cggactagct ttctttggaa tttttggttc gtggataggg attttttaaa
    30061 aaaggagcag agaaaatgtt tacgatgcaa gattatatct atgaagaaaa ggaagtacta
    30121 agtacgatct tgaaaaagaa tgatttttcg acaagagaac atatgaaaaa aacagtgaat
    30181 ttactgatct tagcaacggg ttcatcttat aacgcttgtt tagcagcgaa gccagcattg
    30241 gaatcttatg gtgatcttac tgtcgatatt caagaacctt tttatttttt caattatgga
    30301 aaactttctc cttcaatcga tactgtgatt gctgtgtcac aaagcgggaa aagtgcttct
    30361 actgttgaag cagtaaaaat gatacaaaaa caagggttac ctgttgttgc tatcacaaat
    30421 gacgtgcaaa gtccacttgc tttagaagct gcacaaatta ttgatttagg tgccggggta
    30481 gaatcagtag gcttcgttac aaaaggctat tctgcgactg ttttacagtt actactctta
    30541 gggataggaa ttggaataag taaaaataaa atcagcaaaa aaatagaaca agactacatg
    30601 caacagttgc gcaaaataat caaccattta ccagcgatta ttcaaaaaac ggaagaattt
    30661 tttgatggat atcaaagttt atttcgttta gcacagcgtt tcgtcaccat tggatatggt
    30721 ccaaactggg gaacagctaa agaagcagag acgaaattga ctgaaacaat ccgcgttccg
    30781 tcacaaggat ttgagttaga agcttatatg cacggcccat acctggaggc agatgcttcg
    30841 catttgctat tctttattga aggggaaagt gtaaataagg aacgttcgca aaagttgcaa
    30901 agatatatga gtcggtacgt tggagagact ctcaccatta ccacaaaaaa agcaagaaac
    30961 gagaaaacac ttggattagc aatagaatgt gatgaatatc tgtctgtatt agcgcttgtc
    31021 gttccgtttc aactattcgc ttataaaacc gcagtagcta aaggtattga cttgaacaaa
    31081 aagatttttg aagactttga tacagtcttg aaaagtaaat tataagaggt ggaaatcatg
    31141 ctgaaattca atgaagaaga acaaatcaaa gcaataaaag gcgcactagc tttacgtccg
    31201 caagtagaag aaatcatcga taaactttat gcggaaaaat ttgacgctgt ctattatcta
    31261 ggaatcggtg gaacgtatgc ttcctcgatg caagctgtca cttatatgaa tgggaaaagc
    31321 aacttgcctg tctttgtaca gcatgctgca gaatattaca ctactggaaa caaaagatta
    31381 acaaaagatt ctatcgttat tttgtcctct gttaccggta caactcaaga agtagtgaaa
    31441 gcagtagaac aaatcaagaa agtaggagcg acactgattg gatttatcga taaagcgaac
    31501 agtaagttgt ctcagctatg cgattttgtg gtcacttatc cagctcctgg aacagaacaa
    31561 atcaaatttt ttatggcagc agatcgattg atgtatttga atggagaatt cgaagcttat
    31621 tcagaatact atgaacagct cgaacgttat ttaccaacag ggttagtgga agcagagaaa
    31681 aaagcagatg catttggctt atcatttgca gaaaaacatc gacgtgatag tatgcattat
    31741 tttattggag cagggaatca atggggagct gtttattcat atgccatgtg ttactgggaa
    31801 gaacaaagct ggcttccatc gaaatctatc catgctgccg agtttcttca cgggacgtta
    31861 gagatcgtag aagaaacaac cccagtcaca ttatttttag gcgaagatga acagagagtg
    31921 ttatctgaac gtgtggctaa acttttgcca aaaatttgca gcaattatac attgatagac
    31981 acaaaagact atccagtaga aggtatcagt gaaaaatatc gcggacgtgt tttgtctttc
    32041 ttattgatgc atgtagtgac acaacgcatc gatgctcatg tggagcagtt gaactgccat
    32101 ccattagaga tacgccgcta ctatcgtcag tttgattatt aggatagact ggataaaaag
    32161 aatataaaaa ataaagagag cagcgataac tgctcccttt atttttttaa aatattggca
    32221 tcaattacgt tataaaacac attttttgca ttatctacag ttcaacttat aatctgttta
    32281 atgggacatg tgggtgccaa ccattttttg ttatgcaata gtactattta gttgttgcat
    32341 ggatccgtag taaaagtcca agtacaacga gttgcgccag tttacatagc gttttgtatc
    32401 cagaatgttg actaaaacaa aagttcctat gtcaaccgtc aacagagaca atctgtccgt
    32461 tgcaggacct gacagattta gaaatgttca atctgtctct tatgtatttt aaatcaatac
    32521 tcactaggag aagtttccta acctcctaat agtaatgctg gtagtaacat tgtcaaaact
    32581 gcttcctctt aggaacaagc aaagcataac gagtgtaaaa ataaaatgta gactattgta
    32641 acatatcatt gattatttca agtaaaaacg ataaaagaag taaacaaaca cttaaaaaca
    32701 atggaaatta gtcccaactt taagaaatgt atactataat ggaaattatc aattatttat
    32761 ttggaggaat atccatgaaa caaaaaatcg cagttcttgg tcctggatct tggggcactg
    32821 ctttagcaca aacattggca gaaaacgggc atgatgtccg tatttgggga aatgtacctg
    32881 aacagattga tgaaatcaat aagtatcata caaatcagca ttttttacct gatttgacga
    32941 tcccagaatc gattatcgga tataaagaat tggcagaagc agtggataac gcagatgcta
    33001 ttttatttgt tgttccaaca aaagcgattc gttcagtcgc acaggaactt attggtaaaa
    33061 tgaatactaa gccaatcatt atacatgcaa gtaaaggact agaacaagat acgcataaac
    33121 gaatctcaga agttttggct gaagaaattc cagaagaaaa aagacaggca attgttgtat
    33181 tatctggtcc tagccatgct gaggaagtgg cagtacatga tatcacaaca attacagctg
    33241 caagtattga tcaaaaagca gcagcctatg tacaaaaact gttcatgaat gattatttca
    33301 ggatttatac aaataatgat gtgattggcg tagaaactgg tgcagcactg aaaaatatca
    33361 ttgcaattgg tgccggcgct atccatggat taggattcgg agatgatgca aaagcagcaa
    33421 tcatgactcg aggattggca gaaatcagcc gtcttggtgt cgcgatgggt gccaatcctc
    33481 tgacatttat cggtttgagt ggtgtggggg acttgatcgt tacttgtaca agtgttcatt
    33541 ctcgcaattg gcgtgccggt aacttgttag gacagggaca taagctggaa gaagttctag
    33601 aaaacatggg aatggtcgtt gagggtgtgg caacgacaaa agcagcagta gagctagctc
    33661 aacagctagg tgttgagatg ccaattactc aaacaatcta taatgttttg tataatggag
    33721 aagatatcaa aaaagcagca aaagaaatca tgttacgtga cggaaaaatg gagaatgaat
    33781 tttctcttcg ttaaatagat gatcaatagt taatcgt
//
LOCUS       DAZKPE010000027        32330 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000027 DAZKPE010000000
VERSION     DAZKPE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.027"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            137..2746
                     /gene="clpB"
                     /locus_tag="ACG930_001394"
     CDS             137..2746
                     /gene="clpB"
                     /locus_tag="ACG930_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFQ0518562.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(2897..3583)
                     /locus_tag="ACG930_001395"
     CDS             complement(2897..3583)
                     /locus_tag="ACG930_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518563.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(3561..4055)
                     /locus_tag="ACG930_001396"
     CDS             complement(3561..4055)
                     /locus_tag="ACG930_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFQ0518564.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(4075..5295)
                     /locus_tag="ACG930_001397"
     CDS             complement(4075..5295)
                     /locus_tag="ACG930_001397"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518565.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            5442..7277
                     /gene="lepA"
                     /locus_tag="ACG930_001398"
     CDS             5442..7277
                     /gene="lepA"
                     /locus_tag="ACG930_001398"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFQ0518566.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            7473..8384
                     /locus_tag="ACG930_001399"
     CDS             7473..8384
                     /locus_tag="ACG930_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518567.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            9395..9631
                     /locus_tag="ACG930_001400"
     CDS             9395..9631
                     /locus_tag="ACG930_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518568.1"
                     /translation="MFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTELKDKN
                     NVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            9744..9986
                     /locus_tag="ACG930_001401"
                     /pseudo
     CDS             9744..9986
                     /locus_tag="ACG930_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10076..10315
                     /locus_tag="ACG930_001402"
     CDS             10076..10315
                     /locus_tag="ACG930_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518569.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            10462..14745
                     /locus_tag="ACG930_001403"
     CDS             10462..14745
                     /locus_tag="ACG930_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFQ0518570.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            14844..15209
                     /locus_tag="ACG930_001404"
     CDS             14844..15209
                     /locus_tag="ACG930_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518571.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            15211..15663
                     /locus_tag="ACG930_001405"
     CDS             15211..15663
                     /locus_tag="ACG930_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518572.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            16112..17587
                     /locus_tag="ACG930_001406"
     CDS             16112..17587
                     /locus_tag="ACG930_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFQ0518573.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            17610..17921
                     /locus_tag="ACG930_001407"
     CDS             17610..17921
                     /locus_tag="ACG930_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518574.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            18282..19538
                     /locus_tag="ACG930_001408"
     CDS             18282..19538
                     /locus_tag="ACG930_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0518575.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            19535..20080
                     /locus_tag="ACG930_001409"
     CDS             19535..20080
                     /locus_tag="ACG930_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518576.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            20081..20581
                     /locus_tag="ACG930_001410"
     CDS             20081..20581
                     /locus_tag="ACG930_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518577.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            20940..21218
                     /locus_tag="ACG930_001411"
     CDS             20940..21218
                     /locus_tag="ACG930_001411"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518578.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            21238..21582
                     /locus_tag="ACG930_001412"
     CDS             21238..21582
                     /locus_tag="ACG930_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518579.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            21601..22512
                     /locus_tag="ACG930_001413"
     CDS             21601..22512
                     /locus_tag="ACG930_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0518580.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            22591..23583
                     /locus_tag="ACG930_001414"
     CDS             22591..23583
                     /locus_tag="ACG930_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0518581.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            23580..23798
                     /locus_tag="ACG930_001415"
     CDS             23580..23798
                     /locus_tag="ACG930_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HFQ0518582.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            23811..24221
                     /locus_tag="ACG930_001416"
     CDS             23811..24221
                     /locus_tag="ACG930_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFQ0518583.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            24273..26801
                     /locus_tag="ACG930_001417"
     CDS             24273..26801
                     /locus_tag="ACG930_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0518584.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            26817..29027
                     /locus_tag="ACG930_001418"
     CDS             26817..29027
                     /locus_tag="ACG930_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFQ0518585.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            29035..30126
                     /locus_tag="ACG930_001419"
     CDS             29035..30126
                     /locus_tag="ACG930_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0518586.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            30147..30689
                     /locus_tag="ACG930_001420"
     CDS             30147..30689
                     /locus_tag="ACG930_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFQ0518587.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            30884..31141
                     /locus_tag="ACG930_001421"
     CDS             30884..31141
                     /locus_tag="ACG930_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003657401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518588.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            31155..31487
                     /locus_tag="ACG930_001422"
     CDS             31155..31487
                     /locus_tag="ACG930_001422"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518589.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            31532..32080
                     /locus_tag="ACG930_001423"
     CDS             31532..32080
                     /locus_tag="ACG930_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFQ0518590.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            32087..>32330
                     /locus_tag="ACG930_001424"
     CDS             32087..>32330
                     /locus_tag="ACG930_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518591.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYS"
BASE COUNT        11059 a         5001 c         6869 g         9401 t
ORIGIN      
        1 agatttatat aagtcgagaa aaaaagtcaa aaaactatgt gtatattttg accaaaattg
       61 accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt acctttaatt
      121 aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag aagcgattgc
      181 tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg cccatgtatg
      241 gaaaatcttt ttacaatcta atcattttgg tcgaaatttc tatacggatg ccggattgga
      301 tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag ttgtttctgg
      361 tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat tgaatgaagc
      421 agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg ttattttagc
      481 gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg gattatctga
      541 aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga cctcacaaaa
      601 ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac agcaagtcaa
      661 aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg tcatccgtat
      721 tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg tagggaaaac
      781 ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg aaaatttaaa
      841 agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa aattccgtgg
      901 tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg atggacgtat
      961 cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag aaggaagtat
     1021 ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt tgatcggtgc
     1081 cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg aacgtcgctt
     1141 tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc tgcgtggatt
     1201 aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat tagtagcagc
     1261 agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag caatcgattt
     1321 gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa cggaattaga
     1381 tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga aaaaagaatc
     1441 agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg aacttcgtga
     1501 agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca attctgtttc
     1561 agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag aaaataacta
     1621 tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag aaaaagaatt
     1681 gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag agtccgttac
     1741 cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa cgaaacttgt
     1801 agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac gagtgattgg
     1861 tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg ctggattgca
     1921 agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg tcggaaaaac
     1981 cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata tggtacggat
     2041 cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag ctcctccagg
     2101 ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa atccttatac
     2161 aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata tcttgttaca
     2221 agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt tcaaaaatac
     2281 ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg tgactgctga
     2341 tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg gaaacttcaa
     2401 accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga gcctagacaa
     2461 cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg aacatcaaga
     2521 aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg cttatgaacc
     2581 agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa caccactagc
     2641 taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta ctttacttga
     2701 tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt ccattgagac
     2761 tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt caaataaaca
     2821 gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct gcccgcttct
     2881 gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt tcaaagtaac
     2941 gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca cctatcgtat
     3001 ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac agtgtgccat
     3061 cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag aattcccaga
     3121 actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg aacaaccaag
     3181 gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca tagccaagag
     3241 ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag atgatactga
     3301 tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag taaaacaaaa
     3361 cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc atgaaaatca
     3421 atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc gaatattttt
     3481 gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca agtaaagcta
     3541 tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa tctttttact
     3601 tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat caaacctatt
     3661 gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc agcgattttt
     3721 ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac tgggatgcct
     3781 ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag cccatctagt
     3841 aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc aatcattcga
     3901 ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag atagatcgaa
     3961 agctcagaag agagctctct gatttcttta actaactgtt ggttatataa caaatcactt
     4021 ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt tttatcaaaa
     4081 ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact tcagtgtttc
     4141 ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat aattcatcat
     4201 caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt catttaagac
     4261 acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc aaggagcgac
     4321 aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa accgttgaag
     4381 gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct ctttgatctg
     4441 actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat gtacccagta
     4501 gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt cttgatcaag
     4561 atagaacatt tcttttacgt gaaatatttc ttcagctacc cagtagaaca gaacacctct
     4621 tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat tttcgaaacg
     4681 ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt gttgggcaaa
     4741 tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa ccataccact
     4801 tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt tatcagacat
     4861 gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat aagagatcca
     4921 ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca tcaatccatg
     4981 gttagcatat tctggataag ttccaactcc agtcacacca cccattttat aacgtgcacc
     5041 gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat tttcgtggaa
     5101 ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa aagctcgttt
     5161 attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat aggaaagcaa
     5221 ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat tttctctaaa
     5281 atctttttga tccatttttt catctccatt tattagcttg ataacagtat agcaaaattc
     5341 tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg cttttcgttg
     5401 gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata aagaaaatga
     5461 aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac catgggaaat
     5521 ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc gaaatgcaag
     5581 atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt aaattaaatg
     5641 ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac ttgattgaca
     5701 ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc tgtgagggtg
     5761 ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc aatgtttatt
     5821 tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac ctacccgcag
     5881 cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat gctagtgaag
     5941 ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag cagatcgtgg
     6001 aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg atctttgact
     6061 ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac ggtatggtca
     6121 aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt acagaggtcg
     6181 gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat gtcggttata
     6241 tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta acgttagcag
     6301 acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg gtttattgtg
     6361 gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta gaaaaactgc
     6421 aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta ggttttgggt
     6481 tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc ttggaacggg
     6541 aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt aataaaacgg
     6601 atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta acgattcagg
     6661 atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt gtcggtgcag
     6721 taatggaact ttctcaacga aaacggggag aattcattac gatggattat ttagatgatt
     6781 accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac tttttcgaca
     6841 aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct ggttatcaaa
     6901 aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat gcattaagct
     6961 ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa aaactgaaaa
     7021 aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga caaaaaatcg
     7081 ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt tatggtggag
     7141 atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag cggatgaaac
     7201 aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa atggatgagc
     7261 aagatagtgt gaaataactt ataatcaatc gaaaaaccta ttaaataaac ctttttgagt
     7321 agatgcaaca ctgaggatta tctgtataaa agattttaaa ctgtcatttg gttatcacgg
     7381 cgatactaaa attaacaaaa ttggaatatt tttcttgaag atttttagct gtcagtatat
     7441 gatgaaagca tctcatagga ggtgcttttt tcatggttga taattcaagt ggaagggttc
     7501 ttaaatctct aagaaaagag aaaaaactat ctcaaaaaaa gttagctgat ttagcaggta
     7561 tttcacaaag tactttagtt aaatatgaaa aagggtcaag aaaaatccct aaagacgtag
     7621 ataatactct aagcaagatt ctgaatatag aaactctaat aaaagatgag gaagataaga
     7681 ttgagattct catcggtaaa ctaattgcat acagagatat gaataagtta cttaacaaag
     7741 agttagctga taatatagga attagtgaag tattactcag ttatgtgtta aatagaaaga
     7801 gaaatccgtc aaaagaaatg caaaaaaaaa tcgatatttt tctattaagt aatgaaaaag
     7861 aaattttgaa ggagattaat cgtgatagtg agatatttag tttatcaaaa gacgataaaa
     7921 ttgttatggg aaaaagaata cgagaagtcc gaaagaaccg ggaagagacg cttgaaaaat
     7981 ttggtaaaaa ctttaccatc tatacaggca aaaatgttat aagtagatgg gaaaaaggta
     8041 ttaatattcc agatattgaa aaactaatga atattgccta tcttggtaag gtcactgttc
     8101 cttaccttat gtacggagaa gattataaga atatacttcc aaaagatgaa agagttagcg
     8161 attttaaaaa gataaattct tttagtatgg gattaaggat gaggaaaatt aggaaagatt
     8221 attatctaga aagggaggag tttggaaagc ttttttctcc ttcaatttca aaatggtcca
     8281 tagataggta tgagaatggt agagatatac ccaatactaa tcgaattatc caatatgctt
     8341 atataggaaa tctttcttta gaatttttga tttacgggat ataaaaatag tttacgtcga
     8401 tacttattaa gttatcgacg ttttttatta tagaaaaaat ttataaaagg aggtttcttg
     8461 atatgataag aaacaaaaag ggtttgttga aagttgcttt actggcagct tttttctaag
     8521 taactttttg acaagctcaa tggcaacaca agcggaagaa gtaatacaag aactaactgt
     8581 tatgaataac agctagataa aatgggctat gtatgttatc caacaattta gtaatcacta
     8641 gaagcctagc gaaagttcgc ttgataagtt atagatgagt attgatttgt agtgtttcca
     8701 aatcaaaagg gtacagagcc acatgaaata tgttgtcctc tgcagcgtca ggatgggaat
     8761 ccataccatg gagattcgga gatctgtgag ggaatactta cgtggttaat atgtcagttg
     8821 tgttggacgt agtaatggtc atagtgggta gattgactga attcttatat gagaaaatga
     8881 aaccaacaag aagatagggt tatttataca gaattgggga tcttttctgg aaaagtaatc
     8941 ggataatgcg agattcgtac ggtctttttt aaatttctct aaaaaaaacg gcatcgaatg
     9001 ggttgggtga ttgataagca atgaatcata gactgatata gaataaaaaa tgattctatt
     9061 tatcttttta catctatcgt tttttcaagt agccgcaaat tatatcagca ttcaacaatt
     9121 tttgtataca agttctagta aaaggatctg aagaaaaagt tggttgttgt gaagataaaa
     9181 aaagaatcag gttttactga gtttttcttc aaaatttgtg ttattaggtt aggacaaaga
     9241 taagaagaag tatgaagatt taaaaaagga atgaggaaaa gatagtaatt tccgattatt
     9301 ggagtttttt tatttataaa gaagaagcga ataagttgtg attcctagat ttcgcgcgtg
     9361 attaattaat gagcaaaaaa tgcggaaagt tttagtgttt aatacacgag gacaaagttt
     9421 cttaggtatt gaaggcacac gtgtaacggt tgatgggtgg tgtgattgtt tcgaggttgg
     9481 aaaacatgtt gaacttatgg catttactga gctaaaagat aagaacaacg tggaattttt
     9541 cgagagtgat attggttggg acgatcatga agaagtttat ggaaaattta ttttgcggaa
     9601 gggaaattct tatacgaatg gggaagcata agtagcgatt tgttagagat cattgatagg
     9661 attgaaattg tcgggaatat ttatgagaat ctagagttat ttgaggtgat agaatgagtg
     9721 atggttttga acaagtatca ataattaaaa atcaagttcg ggagattctt agaaaaaaag
     9781 gctatttggt agatagttat tttgaaggag attacgaaac atgggtaggt gtctatgctc
     9841 gtccagagaa taaacctacc tatttagatc ctacgacgtc agaagatgcc tatttacaaa
     9901 ataggtatcg agtagatggt tttaagcaag actttgcgga gtggtttgaa tgggaaattg
     9961 aaaacggaga agtaaaagaa gaataagagt acttgttgta tcaaaataag ccagtagaac
    10021 aaccaaacca gtagctagta atgacaataa tactgaggaa tcggatcatt atggtatgat
    10081 tgatatttct cttccagaag atcttaagcc agatcctgta acaattggca atagtgtcat
    10141 gatttttgat tcattagatg aagctatgtc atatggttgg aaagaaatta aggatgaagg
    10201 tagtaattgg tatggcatga gatttggtga tggtgaagtt gccaaaaaag ctggtattcc
    10261 aattgggaaa tggacagttg atttccacga agcaggttct ttttttgttc tgtaattata
    10321 gtgggagggt aaaatcattg atgaaatgtg ttcagataag agcgccagat aaaaatagaa
    10381 gagacagttc acgtcgttat cacttttggt aacggcgttt tgttttatta tataaaattc
    10441 tcaggaaaag gaggaattct tgtgtatgca aaaacgaaaa tgaattggtt gaaagcactc
    10501 gcattggtgg ctttttctca attctgtttc ttggtgggaa ctgctcaagc acatgcagaa
    10561 gaaacgacgg ctatacaacc tacgatggaa gccattgccc aagtcgcttc tgaagtgaca
    10621 gaagtccaac cagcagaagc cggggtccca gctggtgaag ccactgttga acaggcccct
    10681 gtgacagaag cgccaacggt caattccaaa acgactctcg atcagacgat tggggaaaca
    10741 caacacccag ggaatagtcc tggtacttca caaccagttg aagaaactgc ctcaattaca
    10801 acccctgctt cagaaacgtc cactctagaa ggagaaaaag ctgccgaagc aacgccttct
    10861 gtgcagccag agtcttctga gaaacaagcg gaagaaaaga aacgaataga agaaacagtg
    10921 gaacaaccag cggctactgc tgacaaagaa ggaaaaaatg aggaaaacgt tgaaaaaaca
    10981 atctcttcaa ccgcagctag tcaaaatcaa ccaacgaaac caaacaaaga atctacggct
    11041 agtattgaaa atcaaaagaa aaaagagcag aacattccaa aaacaggtac acctacactg
    11101 ttagtaacag taccaaccaa tcgttcggtt cgtgttcgcc gtgcaaccaa tgcagctgtt
    11161 ttaggtggtc ggaaaattga ttggggcgaa aatattggtg ttacttctag tccgaacaat
    11221 ctaaacttca ctttaaatta tatggttcgt tttgagatta atggacaagt ggcgttttgt
    11281 attgagcctg gtgtctcagc cgcagaaggt caagtttata cagctactgc tttgaaaaac
    11341 tatttgaaaa attcaaatgt acggaaaaaa acaagcttga tctcttattt aggatatgtc
    11401 acaaataaag acaaatccga tgaacaatac attgcggcac aatttatgat ttgggaagct
    11461 ttgggcacaa aaatcccaat caaaaatatc cgtgttgatt atgatcgtcg aaaagcagaa
    11521 attcaacgtt tgattaataa ctttggtgaa aaagcaactt ttaataatca aacacatacg
    11581 gtaaaaattg gcgaaacgtt gaaagtaaag aataaaaatg attttttgaa atatgtgaaa
    11641 gacattcaaa aaccaaaagg tgtcaatgta tctattcacg gcaatgaagt atggattaca
    11701 gtcacaaaag aggcaccgga taaagcaaaa attcaattga ataaaattaa agttcaaggt
    11761 gcgccattag cctatcgtcg tccaggagct caaacaattg gtgtgttaca tccaacagaa
    11821 cctaatgcgt ctgttattaa tttacaaatt ctaaaacaag gaaacattcg tgtgtttaaa
    11881 gaagatgcgg aaactggtgt gaaagcacaa ggtgcagctt ctttagaaaa tgcggtctat
    11941 ggtttgtatc aagcagatgg gaaaaagatt aaagaaatta ccttgaaaaa aattaacggc
    12001 aaagtacagg cagaaattaa agatcttgat cctggcaaat atgttttaaa agaaatcaaa
    12061 gcgccaaaag gttatgtgct ttctgatgaa gcaattgaaa ttgttgttga acctggaaaa
    12121 actgtcaatg cgaccgcaaa agatcaagtg atcaaaggaa ccattgattt agtgaaagtt
    12181 gctaataaag atttagtcga ttcaacgaat ccagataaca aaccaaaatt agctggcatt
    12241 gaaatcactt tgacgtcaaa aacaactggc aaagtggtga aaaccgttgt gacagacaat
    12301 gatggttatg ctacttttgg taaaaatacc gttgtctttg atacgtacat tctttctgaa
    12361 accaaaggaa aagaagggta taaactattt gaaccacttg aagtcacaat ttctgaaaat
    12421 gggcaaactt tccattatgt tttagaagat aaagtaattg aacaacgtct taaagtggtg
    12481 aaagtggatc aagaaacagg aaaagtgatt ccacttgcta atacagaatt caagattttt
    12541 gatactttag ccaatcgtta tgtcacaatg gagattccaa atgatacaga aacaacggat
    12601 atctttaaaa ccaatgaaaa aggctttttc ctaactaacg gtacacttac ttatggaaaa
    12661 gatcgctatc gtttggaaga aatcaaagcc cccgtaaatt acgttttgaa tcaaaaccca
    12721 ttagtgttct cgattaccaa tgatacagaa ccgatcaaag tgatccattt tgcgaaccgt
    12781 caagcacgga aaagtgtaaa attattcaag tatgaagaat ggaacaagaa gaaaacgccg
    12841 ctcgcaggtg tgaactttac cttgtataac ggtaaaaatc aagcaattgg tgaatatacc
    12901 actgatcaaa acggggaaat tttagtgaaa ggtctagttg ccgatgacta ttacttcttg
    12961 gaaaatgccc cattagaaag tttccaacca aatacagata aacaagcatt cacggttgca
    13021 ttcaaacaaa atgcgccaga tgatggggaa acgttagtgg tttctgtacg taattacttg
    13081 attccaccaa aactagaaac acaagcgtca aataaagccg atggtgaaaa agtggttgat
    13141 ccattagaaa cgatcgtcat taaagacagt gtttcttata ccaacttgtt tgtcggaaaa
    13201 gaatacacca tttcaggagt attgatgaac aaggcaacga atgcgccaat tttacaagat
    13261 ggcaaagaaa tcacaagtac cttggccttt attgcagaca aagtcaatgg cacaaaagac
    13321 cttgaatttg tggttaatgc tagtgttctg aaaggtcaaa cgatcgttgt ttttgaaaaa
    13381 cttttccgtg atggcattga agttgcagca catgcggata tcaacgatga agcccaaagt
    13441 gtgaaagtga ataatccaac cgttcatacc acggctgtct ttgaagacgg attgacagtc
    13501 gcagacccaa caggattgtt taccttaaac gataccgttg aaattaccga gattcttcca
    13561 ggaaaagcat acttggtcaa agggatctta atggataaag caaccggtga acccttgctt
    13621 gtgcatggaa atacggtaga aacgagtgtt ggctttattg ccaaagcaga aaatgaaacg
    13681 gtgatcgtac catttacctt tgatttgaca ggtataaatg gtcgtgaaat cgtcgtgttt
    13741 gaaagtcttt ttagaaatga tgaagaacta gcaaaccata aagacatcaa cgacaaaggg
    13801 caaacggtac gagtaactaa cccaagtgta cgtacaacgg ctacacataa acccactggc
    13861 ttgaaagagg ttaatccatt aacgaaagtc accattacag acgctgtgaa ataccacgat
    13921 ttggtcgttg gaaaaacata cacagtcaac ggtgttctaa tggacaaagt aacggaaaaa
    13981 ccagtgctag tagatggaaa agaagtcaca agtaccttaa cgtttgtggc agaaacaacg
    14041 gatggtacag tcaatctaga ctttattcta gacgcacgtg cgttgcgagg caaagaagtc
    14101 gtggtctttg aagatctgtt tagagaaggc gtattattgg cttctcacgc agatattacc
    14161 gacaatgacc aaaccatcaa aatcagtaat ccaaccatta cgacgaaagc gacgaataaa
    14221 aatggcggaa aagagatctt ggccttgcca aatcaaactg tgcttgaatg ggtcaaagta
    14281 gacggtcttg cgattggtca aatctatcgc ttaattgttc aaggctactt aacaccagac
    14341 ggcacaccat ttgaaggcac tcatgcggaa aaagtctttg cggccgataa agaaatgatg
    14401 gaattcttat ttgaattctt agtggacggt cgcaatcttg caggaaaagg cttgagtttt
    14461 gcggaatggc tccaagcgaa aacggaagat gagaaagaaa cgtttgaaga agtggcgaaa
    14521 cacaatgtag atctaacaaa caaagatcaa acggttcaaa ttgtggaagc gccaaaacca
    14581 ccgcaaccag tgaaaccaga acaacgggtt aaaccagcta ctgttgtacc aatgttgcca
    14641 aaaacaggtg aacaaacaag tagtatactt atggttcttg gattagtagt attagtcatt
    14701 gctttaggta taacacttta taaagtacgt aaagccaaag attagtcatg aggaacaagc
    14761 ggttaggatt tttaaccgct tgtttgattg taatgtagaa atatttagaa tttattttgg
    14821 tttttaagag gaggaaaaac tttatggcag aaaaagcatt gcgtatgaag aaagagtttt
    14881 taggtcaagt atttttattg ggttcacggg aacctaatcc accaaaggaa attaatggtg
    14941 tgtctgggcg atatgttcaa ttacaagcag agtgttcgcg agaagaacag cctgcttttt
    15001 ttgtttatct cacagctgaa gaggataaaa gattacgatt accagaaaaa gaggtgcgta
    15061 tttcatttga agaagcttat tttgtttttc gtaaagaacg agtgaatagt cgtgaaacaa
    15121 atgatatggg acaaacagag cgtcgaacaa ctggctatca agatgttggt gtctttttaa
    15181 ctggtgtaaa aattggggag gttttgtaag atgggattaa aatttccaaa taattatgac
    15241 attacagaag cattagatga aacttgttta ggagccgtac gctttggcgc attagaagag
    15301 tctgatcgtg tatttgataa tgaaacaggc gattatacgg gagaaattcg atcacagcga
    15361 gcacaattag tttttggaaa tccagatgaa ccaaagattg cacgacgagt taaatttcca
    15421 gcagatgtag atttgactgg ttttaaacga cgtgatcctg tgaaattaat tgatccagaa
    15481 tatcatgtgg tatatattcc agcacaagat ggcaatcgtg aatattcaga tttagtgatt
    15541 tatgcgaaag gattagagaa agtagaagct ccaacaaata atcctaatat gaaacaatca
    15601 caagaaaaag gtttagatca aaaacaacca agtgttgatt ctaaggaaaa agagaaaaaa
    15661 taaggttttt ttgaaagaat aggaaggagt cttcctattc tttttatcta agatagaagg
    15721 aaggggagat tttgaattca gataaaacca atcaaatact ttgagagatt gtgcttgtta
    15781 tcaaaatatc caacaattga ttgagtattt tggagacaat ccaacgattt ttgtacaaac
    15841 aaatgcatat atttgtgcgg ttattgggca gtgtatgttt ttacgtgatc ttgttcgttt
    15901 ttcattaccg taccagtgga aacaagatca tcaggaagtg atttggattc gtatagtacg
    15961 aatatgtaat atgtgtgcac acccttataa aaatcgatta aatctttttc gattatgttt
    16021 ttttactaaa tgtgatattc ctgtattagt tgctttttgt caaaagtttt tagcacagga
    16081 aaagtaaaaa cagaaaggag gaatgtgaca attgaaagct cattttttca agtatcgtgg
    16141 tcggcgaatt cgctatttca atcgttattt atggttttgc tattatggtt tctttttgtt
    16201 tccatttttg attctgttag gttggtttag ttggaaagta ttttatccac gtttaagtac
    16261 gttttcgaat tggcaaatgt atcttattcc tggaataagt attgtgttgt atttgttgct
    16321 ggttagtggg ttaattttag ggttgatgca ttggtcgcga ctaaaagaag gatattttgc
    16381 ctctgtttat tggcgtcagt tacttgttcg aatgttaatt gacaatcggt ttgtttatac
    16441 aaagaaacaa gttagtgaga aacaaacaag ggaaaaaatg agattaccaa aagtttattt
    16501 ttatcaaaag aaacaagaat tagtggtttc ttttccttta gatggtgggc gttttcacga
    16561 acgattttta aaaatgggtc atttgttatc tgaagtattt ttgcgtgatt taattcgtga
    16621 agaacgagaa aaagcccgaa tcaattatgt attcctttca gattctggtc ggattcctat
    16681 tgatcaatgt atagcagaaa atggacgtat tcatttaatg aaaactttgg attgggtata
    16741 tgatcaatca ccaaatatgt tgattgctgg tgcaatcggt ggtgggaaaa cctatttatt
    16801 gtattcttta attcaagctt gtttaagtgt tgggacagta gatatttgcg atggaaaagc
    16861 ggcagattta gcagcattag gtgacgtcga tgtattcaaa ggacatgtgt tttacaaaat
    16921 aaatgaagaa atgattattt gtttacgaaa tgcattaaaa gaaatgaatc aacggtatgc
    16981 ctatatgaaa accatgaaag atcctaaata tgaaccaggg aaaaattatg cttattatgg
    17041 gttaccaccg cattttatct tttttgatga atgggcagct ttttatggtt cgttggatat
    17101 ggaagcgaga aatagagtcg ataaattgat tcagccatta gtattaaagg gtcgtcaagc
    17161 agggatgtac attattttag caatgcaacg accagatgca gaatattttc caagtggtgt
    17221 tcgggataat ttaacattcc gtatttctgt tggtcgattg tctcccattg gttatttaat
    17281 gacttttgga gaagatttta aaaataagcc attttacaac aaagatcaac ctggtcgtgg
    17341 atatgctttt ccaggatttg atgtacctgt agagtttttt gcgccatttg tttacaaaga
    17401 ttatcacttt atcaaagaat ttgagaaatt tactgaaatg attgtctatg attttacagt
    17461 aaaagaggat agtcaagatc aaacgatggg agatgataat cagttgttac aagaacaact
    17521 agagcgccaa atgtatttag caaaagatcc aaaaggaaca agtttttctg atgcgcatat
    17581 tttgtaatca actaaggagg tgaagttaaa tggcagagag ttgttattat agagtagcta
    17641 cagcaatacg aatgattaat ccttctcttt cttccagaac gttttatgat tggttgaatc
    17701 gtattgaaca agtaactgat taccgctttt tgcgcaaaga acgtgttttt acaggaaaag
    17761 ttattaatca agtattgcta acgaaaaaag atatagaacg attgactcga ttgtatcatt
    17821 atcgagtaga tttagaagag gatttaactt tgtcaattta tcgcgttttt tctcctgaaa
    17881 aatatagtga aataacaaaa ttagatcatt taattttgta gttattatct atcgggaggg
    17941 ctctagacgt agtctggtag ccgcactctg cctggcggtg cgcattaagg ctgcgaagca
    18001 tgggcctata atgcgcactc gctagcagcg tgtgcagctc acaaagaggt cgtgcgcttg
    18061 cgcacggcct ctttgtgtaa agccccccga tatataatat ggggggcaga aataacataa
    18121 cacatagaaa aaagttttat aaaccctttt gtatcaagtg attatctaag gtcagcagtt
    18181 gtactacttt tcccaaaaaa cgagggggac tagttgatat atcggtgttt ctaaagggtt
    18241 aaaaaaaatc gattttgtta ttttataaaa ggagcgagaa aatgacaccg attgagctaa
    18301 aaagctacag aaagaagtta agtgcaattc ataatataag tggagataaa aagccgctat
    18361 cacaagcaag atttgcgcaa ttgatgggct gctcaaaaga ttacattaga aagatggaac
    18421 aagggaaaag aaaaatccca gaggattttg aacaacgaat caaggaacgc tttcgattgt
    18481 atatgaaaag cggaatagat cttcgagcaa tgattgatta tttgcgtctt tccttttttg
    18541 ggacagacta caaaacagtg attcaacgtg tattacgaat ggatctgaca gaatttgaaa
    18601 cacgtccaac gggcttgtat ctttttgact gtctttctgt tcgtgggaat atctgggtgt
    18661 tctggcattc aaaacgaact gtaacagaaa atgtacttgt gcaattttca ggacaaggtt
    18721 gccgggaata tgaggaagtc atgcgtgaac aacaaacaga ttggcgaaca tggctatatt
    18781 ccatttggaa aaatcaagga aagttggaag ctggttatac acgtgtgcaa tgtagccgat
    18841 tcgatattgc gttagatgaa ctttggggat tggaaacgga agaacatttc gatctctttg
    18901 aattactaga aaaacaaaaa gcaggtttat tagaaatgga ctttaagaga ttccagaata
    18961 ttggcggttg ttttttagat gatggctatt ttcgaagtga aggattatct ttgtattttg
    19021 gatcgcgaaa gagtcctctc ttttttaatt tttatgagaa acgttttgaa attgcgaacc
    19081 gagaaaaaat ttcagaatta gaagcattaa cgaaatatgg tatttataat cgatatgagt
    19141 tacggttagc caatgagaaa gcaacacaag cagtagaagc atttatttta ggtgattcac
    19201 cgaaacgttt aggagagatt ggcgttggtt taattaatgc aaaacttatt gtttgggata
    19261 gactggaaag tgatgcacgg attgttgata aacgatgggc aaaattattt cgttcgatgg
    19321 aagaattgga ttttacagta aagccagaaa aattctcatt agatcgttca gaacgctggt
    19381 ttttgaaaca agtagctccg acattaaagt tgttacaaga agcagatcgt attttaggaa
    19441 gagactttgt acaagaaggg attgataatg ccgaactaaa tgacgagcaa caaaactatc
    19501 tagaatggat gggaacgtca ggagggaaaa ttgcatgaat gcatatacga caacagaatg
    19561 gctgcgcctg ttggatttaa aggctgcaat cgaagcatta aatgaaaaga tggttgattt
    19621 gtcttatttt cgttttcgag ttccttatat tgaacaagcg gtaaaagctg gacgttatca
    19681 ggaaaaagag aactggcaag aaattgcacg cttattagaa gttcgtaagg gatacgaaca
    19741 agaactcgaa gagttggaat ttagccgaag gaaaggaagg ctagaattca ttcgctttta
    19801 tcgattttca ttgccaatac ctgcgatttt agcggttaaa aaaggctgcg ataaaatgaa
    19861 gatatatgaa aactgtgtgg cagcacttag cagcgaaaaa cctcttatgg aagaaatttc
    19921 attggtgact gtcacttggg aaatgagtcg ccagccaaca gaagaacaga catatctttc
    19981 tttagaagag attgagatag aattagagga aattggtcgc tatgccactt gttctaccta
    20041 ttgtggatcg gtcattagta ttgctggtgt gattgtctaa atgaaaaaaa ttatgattta
    20101 tgttggtgcg tattggtcac gtgatccaac agtattagaa aatccagagg cggtacacta
    20161 ttgcttgcgc caattattct atctgtataa agaacgatta gaatcgttga ttcgtcagtt
    20221 accatatact gacagacgtt tagatgaact tcttctaagg tatccagcaa tgtataaacg
    20281 acgaaaaaat agattgttac cagaagagta tcccattgaa aaacatgaac ttgaagggcg
    20341 atttgtggct tatttctatg atgatgttcg tatgcgctta gtagaacaac gaatggaaat
    20401 agaaaatgat cgctactatt ttatcaatta ttgtaagaag cgtaagtatc aagtaactga
    20461 tgatttttat gattgtattt tacaagatgg ggaagtgatt ctatccaaaa ttgctccaag
    20521 ttttcgtgaa cttgtgccga ttgatttttt gaaaaaatgt catttgcgga ttcttccgta
    20581 aaaaagagct ataaaaggaa agaaaagtag aagccaaatc ggtttctgct tttttatttt
    20641 ttttaggaag gagaagatgg tatgtcactg gaatttttag gagagccaat tgaaaaggaa
    20701 gagttcgttt cgcattatat ggatttgttt attcaggtga taaaaaactt tgtgcgattg
    20761 atgaatttta tccacgcgaa caagactatc tagccgctga acgaataaaa atcagtttat
    20821 tatgggaaaa attcacagat gaaaataacc gaccgccaga ttatcgctat ttatcagatt
    20881 gtttaacgaa taatgtgctt tctaaagaat acctatttca caaacgtgag aaaaatcaaa
    20941 tgtcggttga acatttttgt gattgttata ttgcattatt gcgtagtcaa cagttattaa
    21001 cagtagaacg atatggtgca gagtttggtt atgtcatgca agctgagcgt catagagcta
    21061 caagatgcta tgaaaaagaa gatcaagtga ttgatggcta tgaagaatta tgtattcgaa
    21121 acaatcgcta tttgcaacaa cgtttatatg aacaattgat gatggatttt tcaaatctct
    21181 atagagggta tgaatgttcg atgattcaag aaaggtagaa gaaaaggggg aatttttatg
    21241 tggcgattat tatttttggt ggtatgtggt atggcattgt tctatgtgta tcgtgtctat
    21301 ctctatccac gaatggaacg atggacaagt tggtatagag atcctttaaa acaacgaaaa
    21361 ggattgaagc ggtatcgtta tgaattactt gttgaatttt cggatgggcg acaagcacag
    21421 tattattttt ttgcaaacta tccaaaatac aacaccagtg aactattgat tcaattattc
    21481 aaaaataatc catatgttgg gttagaagaa aacggacggg agttctttta tcgttcagat
    21541 aatattagtg cggcgtctat gaacaaaaca cgaattgcat aaaaaattgg aggaataatc
    21601 atgaaaaaaa caacattagc agtcgtaaca acactaggaa tttcattatt ttcgtttcaa
    21661 ttagggagtt cattggttta tgcagatgaa actgtagaaa cacctaagtc agaaattgta
    21721 gaaacattgc caggggaagg attaccagat gttgagacag agctaaatgg aggaacaacg
    21781 gaaaaaccag cagaacctga acaattgcag tcagagaaac ctgaaaaaga gccagtgaca
    21841 ccagaaccag agtttcctga atcaacttta ccgactgatt cgatcgaaga agaaggtgtg
    21901 catagttcaa caacaacgga ttcaagtata gtcacaactc cggaacaatc aggaacaacc
    21961 agttcttctg aaaagaatac tgattcgtca agtacggaac agccaacgat gtcgtctacc
    22021 agtgaagaac aaaaagaaga accgaaacaa cctgttgaaa aatcagaagc aattccaaaa
    22081 gaaaataaac ctattgttcc agcaaaagaa gtcacagtat cggtaacccc aagcggtgaa
    22141 attacgacga atacttctca aggaatgagt gtaccgattg tcactagtaa tgtagaggaa
    22201 ttgacccata ttccaacacc aaccacccca ttaaaagtag caggtgatca aacaattgtt
    22261 ggtgtaaaag atggtattcc attaatccaa gatagtgaag ggaatttggt aaaggatttg
    22321 tcgattcctg taaagaaact tccaagtggc aatattgaaa tcaaaacagc agatggaaaa
    22381 acaaaagtct taccaaagac tggtgaagaa atacatgttg cactttctgt tctaggagga
    22441 gtgttgacaa gtattgctgg atttgttgga tataaaagaa agagaaaagg aatagaaaat
    22501 gagggtaatt gaatggacta tttttcagaa aaacaagctt atcgttgtca atcgtacgta
    22561 ctagtaaaaa catactagaa ggagtagctt atgaaaaaac gacaactacg gcggaaagaa
    22621 aaagtttata cagagaaagt accgaagcaa aagaaaatcc attcaaaaaa agcagtgaaa
    22681 tggatttggt gtttggtttt atttctttgt ttttcagggg gcttggcatt ttttcaatcc
    22741 atgaaaacga aggttcaagt gtcgtttttg aaagatgaaa tccaacaatt acaaaagaaa
    22801 gaagtacaaa gtcggtcaga attaacgtac acacctgaaa ttgaatcctt tatgaatcgt
    22861 tttgttgctt tgtatatgaa tacattcgat aatcatgaac aagaacaaca acgtcaagaa
    22921 acattaaaaa aagagtttta tgcacaaaac tttattcaag aaccaggaag tgtttcaggt
    22981 gttcgaaaat taactgctgc ttcgtttatt ggattaaaag aaattgaaac cattccaact
    23041 gctagttata aagtaactta tgatattcgc tcgatgaatc cagagagtaa gaaagaaaca
    23101 agtgtgacaa tcacacaagt actcaatctt cccttttcta tttcaaacaa gggctgtcgt
    23161 attattgctt atccttattt tacggcacta ccaaagaata cagaaaaaca acgaatgatt
    23221 acttatgatg acacattata cgaaacggtt gatgcgtcgg aagcgaaaga tgttgaagga
    23281 tttgtggaag atttcttaga taagtatgcg aaaaacaatg caaaagatat gtcatacatg
    23341 atgaaagaac ctgaaggact caatcaaaca gctaaagttg atcaagtaga gatgaaagta
    23401 ttgcgttata aagaaacgaa aaaacctttt attgtaaaag caacggtcgt ctttcgagat
    23461 ggtgatacgt cacttttaca aaaagaacaa atgacgattg tcattacgaa aaaaacaaat
    23521 cagtattatg ttgaaaaatt aacacataat tggttggata ggaaaggaga agaacggaaa
    23581 tgacactgaa gggaattgta gattttatat taacgcaagg tggctatttt ttaataatgg
    23641 tggttgttta tctgggattg cgaaatttta tgaaatcaaa agtaggaaat gcattaatat
    23701 ctatcgcagc aggtgccgca gtttatttct tcttaaatga tccaacacgt gtatttgatg
    23761 cgtttggtaa aatcattgaa aaattattta tggattagga ggatagtgaa gtggattggg
    23821 aaccttatga ttattcgatt gtttatgcgg aaccttatcg cgtacaacag attacaagca
    23881 attggcgtct tccatttcca gttgcattag tcaatgcagc aacttttttg ttggtcgtaa
    23941 tctttgaata tttattttta cgttcattta ttggttgggt catttctttt tttccaccag
    24001 caggagttgt tttttatata ggactcccct atttatgtgt gttagcactg gcaaaactaa
    24061 aacctgatgg aaaaaaagtg catttttatt tatgggattg gttttgttat atgattcgta
    24121 tgatgaatgg tgattgtgtg tattataact gggacaaggt atcaaacaat gcattggaag
    24181 aattactttt tgtgaataag tatgtttatt tagaggatta gaaaaaggga caatcaactg
    24241 gttgttcctt ttttattggg aggtgaaatt cattggtgct tgtaaaagaa ccagtaaaag
    24301 cattcaagaa aaattgtttg ttaaatggag aggattgtat ctgggcctac tatcatgttt
    24361 ttccacgaac aatttcaaaa aacacaccaa aaaagacaca ggaaataaaa gaaatgatgg
    24421 ctcgtttact gttgctttta gcagattatg aagatgtgga gttggtgatg tatccacgaa
    24481 caatgaattt acggacgaag tttgacacat taggaaaggg attttctccc gatagtcaag
    24541 caattggtgc gtattatgca aaagaaacag tgacattgtt ggaacgagaa ggtcaagtct
    24601 atcgtccttc atttatttta ggaatcaaag tcaaagaaaa agcaacggtg gagagttttc
    24661 atgatgtaat aaatctaatc tggttagatt tagcaggaag tttagcacgc ttatttggat
    24721 tagaagtaga tgatttggaa actttgtttt ctgaaagtga tccttatgta aaagaagtga
    24781 cacaattact ttatagcttt tctattcgtc ccttagtaaa aaaagagctg ttgtatctca
    24841 atcgtctgca atatattcga ggaatggctc acaaagtaga agaacaaaat aattgggaag
    24901 tactgaaaga caatcaagga acgtatgtac gtataccgaa ggaacataaa ggccttcttc
    24961 aattagaaga tgagttaggg agtagttatt tagcattgtt gcctattggg gaaacacctg
    25021 aaaatatgag aaattgtgat ctatttcaat ttgctcagga tctttctttc ccagcagaat
    25081 tgcgaatgaa aattcactat ccacgcttga aaggacaggg aggtattggt ttaaaactga
    25141 attggctatc ggaacggttc aaaacagagc ataaggaatt ggttcaaaat gatgaagaac
    25201 ctagtgaacg cttattaact gttcgaggat tagtaaaaca tttaaagcaa cgagtagata
    25261 atgggcaacc tgtcgtcgat tggatcgcat gttttattgt atacggtcaa acggttgaag
    25321 aagttcgtca aaatagtgca acggttattc aacaacttca tacgattatc catatccacc
    25381 gtgcaaaaaa tgatcaacga gaattgttct ataaatgttt attagggcaa ccattgggac
    25441 ggcagttaca ttggaagcac cgaacaactg tagaagcagt tggcgaatgg ttgttttcag
    25501 cagtatcaga attaggtatg gaatccggct ggtatattgg tcggcaagat acattagggg
    25561 atggtggttc tcgaggagaa aaaacaccat tagaagaatt aatttatgcg tcaaatcgtt
    25621 ttgtcttttt gaatcttcta gccattgcgg aaggaatcaa aggtgcgttg tttgatgcgc
    25681 ctcatgtagc agtaactgga aaaaccggta aagggaagac ctttttagtt ggcttgctct
    25741 ttttgtatag ttcgtttatg aatgtacaaa gtttatttgt ggatcccaaa ggagaaaagc
    25801 gcaaatggtt tacgaaactc attcaagacc cgtattatca gaaacattac cctttgtttg
    25861 tagaacattt gcaaaaaatg agttatgtca cgttagatgc tacaaatccc cgtaattatg
    25921 gtgtattaga tccaattgtt tgtttatccc gagtagatgc gaaacaagta gcccaggata
    25981 tgattgatga gttaagtccg ttaggtacca atcacctttt aaaaggggcg gtattaaagg
    26041 gaatccaaga agttttagtt caaaaagaag ccggacaaca agttggcttg atgcatgtgg
    26101 tcgactattt agaacaaatg gaacaaaaag aggttcgaga atatggtgag tttttacgct
    26161 tgacggtaga agattcgatt ttacgtttag gattttctta tggagaaaac ccgggattag
    26221 actttaatgc caaaacaacg attttagaga tccaagattt gaaattacca aatgacaatg
    26281 tccgaccaga actatataca gatgcggatc gaaagtcttt gtgtttgatg attagtttag
    26341 gtcgtttttg tgaaatgttt ggaaaacgag atagtagtaa gaaaacagcg atttatttta
    26401 cagaagcatg ggtatttaat aattcgaacg caggacgtag tattattgca gcaatggcac
    26461 gtgtggggcg ttcccagatg aatcaattag tgttagatac acaatttatt ggtgacttag
    26521 gttcagataa agaaaaaggg aattttggtg tcgtctttgc ttttgatgaa gacagtgagc
    26581 gagaaaagat tttgaatcat ttacgtttgg aagtaaatga agcgaactta gctgaaatga
    26641 gccacatgat taaaggacag tgttggatgt tagatcccta tggacgtgta ggaaaactca
    26701 atgtacacag tttgtttgaa gaaatgaccg ctgcattaca aacaacggaa aaaacaagtc
    26761 actctcaagt agaagaacag gatacgttaa tcatgcaata gaaatgaggt gaaacaatgg
    26821 cttatataaa gcataaggaa aagaaatggt gcgttttgtt ttttttaacg attggattcg
    26881 gactgctttt tgttggtgga ttggtgtatg cggcagaaaa gcaggtggat caatcgatct
    26941 atgagattgg gaaatttcat attgatacct tttcttctta tttatctgat agtgaatttt
    27001 cattaggcaa aatgttattt ggggcaaatg gcacagattt tctaaaaatg atgacgaata
    27061 tgttctttag tttaagtaaa ttgatttggc aaggccttga ttttgtcatt gagaagctct
    27121 atgaaggagc tgcaatgaac gagttaattc accagttttt cactttttcg gatactattt
    27181 attcaaaaat atacgatcct attggtgcgg ggattgtcgt cttgtatgtg ttatatctat
    27241 ttactcttcg tatatttaga gggaaacatt acgcaaaaat ggtgtttatt cgatttctct
    27301 tcgttgtcat tttttcaatg gtttggtttg gctatggtag taacgtacct agtaaaggag
    27361 aagcttttac caaagggtta aatgatttgt ccgtggaggt agaaggcttt attttttctg
    27421 ctacaaatag tctagatgaa ttggcgacaa aagatgtcaa tggtgtttta gtgccaacga
    27481 cacaaaagga agccattcaa aaagtgcgcc aactttatta taaagcggct gttgttgatc
    27541 cgtatatatt gttaaattat gggacaacaa atttagaaga attgtatcaa gcagagattg
    27601 aaccacaaga atttctagcc aaggaagcgt caagtgaaga attatctgat attgagacaa
    27661 aagtgaccac tgctgcagga gaagatagag ggaaaaagaa ggcttatcgt gtctatattc
    27721 aaccaactaa agctgtttat aaagcagtcg ttggttctat ggtgccattg cttaatctaa
    27781 gtattggatt accacttgta gtgattggca tgattcgttt tatctttcaa atgttggtgt
    27841 tgtgtttatt acttgtgatt cctttttcat tactcgcttc ttttgttcca gtatttgatt
    27901 atatgctcat gaatacctta aagtcctttt tgggcttgat gtttcaaaaa tctttttaca
    27961 gtgtgattat tttggtggca tttttgatct ataacatagt agacgattta attccaatga
    28021 atactgtttt tggtttttta ggaaatatgt ttgtcaaagc actcctatca attttactca
    28081 ttgtaaaacg gaaagattta ttaaagaaac tagggttagg agctgcagat caaactataa
    28141 acaacacgaa aaacatagca agtcattctt tgtctcaaat gaaacaactg cctggtcaac
    28201 tatcaactgc tggacaaaat ttggcaatca aaggtgcagg attagcaggg aatgtgtatc
    28261 gagcaacgaa tccactcgct tctgcagcga tacatggatt tcaaaagttt caacaaaaac
    28321 gtacaccaca agaatcggta aaagggaggc aagtggttaa tccctttgaa ctaggtgggc
    28381 gttcaaatca agccttgcct tatagtggtc gtcatgttcg ttatcatggg gtagagcctg
    28441 aaatgtcttc taccaaatcg aaaacagagt ggaattctgg tctttcaaat ggtttgattc
    28501 caaattcgtc catgaattca gtaagaccaa aacaacaggt acaatcattg gcacaattga
    28561 gtaagcaaca agggaataat caaagaaaac cattgttaaa taaaggtatc gcttttgttg
    28621 gtcaatcgat tccgttgcct tctggaaaag tacccgtgcc acaattaaca gctgctggtt
    28681 ctctttcaca acagattcgc caagtgaaaa atcaggcgaa aaatgggagt tatccagcaa
    28741 tgcagcagtt attgaaccaa tactctgttc ctaattcgtc ggtagccact ctatcaggaa
    28801 atcgttctgt gcaacaaccg gggcaacgtt cgtctgaaag taaaccgtcg atttccgcac
    28861 caaaatcgtt acaacctgca ttttcttctt tagataagcc aacagagcaa tcggaaaaaa
    28921 tagaaaagga tcctaaaaca ctgccgattt tggacgcaaa accaggaact gattttactt
    28981 taccaaaagg acgaacagtc caaaaaccat tatcgaagaa aggatgagga agaaatgaag
    29041 aaagggtgtc taggttgtct tcttttcttt attcttccct tttttctatt gccattcttt
    29101 ttttcaggag aactttctga gcatggagga gaagctacag gtctagctgt cgcttttaat
    29161 ggggaatata ccgaaggatt accgattttt tcagagatta aaggacgtgg tccaatcaca
    29221 gatgaacatg cgcaagcagc agttggtgca gctgtaaagt atcagttatt accgagtgtg
    29281 attctttctc aattaggcta tgaatcagct tatggacagt cacaatctgg aagaaacgat
    29341 acgaactttt ttgggattac ctggtttcct ggttgtccct acccacaagg ttctgcacgt
    29401 ggaattggtg gttctgaagg tggtttctat atgaagtttc cgaacttaaa agcttgttat
    29461 gactattatg gctttatggt ggcgagccaa agcaacttta atcaatgtgt gggcaataaa
    29521 gatcctggaa gttgtttatt gattctaggt cgtggaggct atgcggcagc aggtattacc
    29581 gaagggagtc cgtattatcg aggagcaatg agtatcataa cgtcctataa cttaacggaa
    29641 tatgatactt ttgcgatcaa gcattggaat agcctaccaa caaaaaaaac ttcgcttatt
    29701 gcaggaaaaa gtaaaggcaa tgcgaaggtt ttggatcgga tcattggacg atccgtaaat
    29761 aatggggaat gttatggtgg tacggcatgg tatgtatctc aattaggtgg cccacagtta
    29821 atgggttctg gacacatgtt tgcgatgtta ataggggaag attataactg gacaacctat
    29881 ggttggcaag taatcatgaa cccaaaacca agtgatttac aagcaggaga tgtggtgaat
    29941 tggcaagcag gtggtgcatt gtctcctgga atctatggtc acaccggaat tataacagat
    30001 gtttcatatg gcggacaaca tttctctagt gtggaacaga atgccgagca aggacggatt
    30061 atggctcggt atcaacgcac gtacaatcaa acaaaaattc gtagtctggt tcgtaaggtg
    30121 aaataagaaa ggcagtgact agaaacgtga aaaaagggat aattttagta tttagttggt
    30181 tatgtttgat aggtcttact ggttgtcatt ggttttcttc tgaaaaacaa aaaacacaat
    30241 tgagaacgac agaagaaaca atcgaagcag taaaagaaac aagtggaact cttcaaagta
    30301 ctgaaagtaa cagtcaaatt ggttcattag aagacgagac agcgcaacaa atgcaaatag
    30361 atgaaatgac aaaaaatttc ttaaaagatt ttgctagaaa atggagtaat ttcacagatg
    30421 tttataaacg caatcaagct gtgagggact atatgacaga tcgttgtatt aaagacaata
    30481 gtattgatgt agacccgcat gtacaaatga aaacaactgg gaaactttac caggtgacac
    30541 aagatataga gaatccggat caatatttgt tatttggaga agaaacaatg aataaggtta
    30601 ctcaatttgt attacttcaa ttgaaagtag atcaagaagc tcaaaagatt gatgcgatca
    30661 agatttatta tgtacggagt gcgtattaaa ataaaaaatg aacactcata tttattatac
    30721 accgaagaaa tagaaaaaaa cagactgttt ttttaagaaa aactatgtca ttctttactt
    30781 gaaaaaagtt gttataggac agaaaggata aaacaaaaac ggaaaaaata tgtcttatga
    30841 ataactataa gaactattct attttttagg agatggatac gagatgaaaa aactaattgg
    30901 ctatagtgtg atgtgtattg gatttgttgg tgtgggattg tttgtatcga ctgaatctgc
    30961 ttctgcggct gaatggtata atcctatctg gtataatccg aacattgaat gtcaaaaagg
    31021 ctatccgtat ggaccgacaa atctgaaaaa tggaaaatgt agagtaaatt ggaatggcgt
    31081 tgtagatagt gtaattactg gttcaatgga ctctgctcta catggcttta cgggtcacta
    31141 gaaggaggaa gaaaatgtct gaagagaaaa aagaaatcgt tgaatcatta gtagctttaa
    31201 aagattctct ttctaagatt gaatatgttg ataggcaaga aattcaaaaa ctaattgatg
    31261 atactattat tgaaatccaa gatgcgcgtt gtgaaggtat aaaaatttct gtagctttat
    31321 ctaaagtaat agaaaaaatg aaccgttcat tagcgtttaa tggattgaag ctagatagac
    31381 aaactagtct gatatgggat catttaaaag acttgtatga caagtctaaa agaagtgaac
    31441 ggactgctgt atcaatctta aaaggccttt ggggaatgaa ttcataaaca agatatttaa
    31501 aaagtaactt attttttatg gaggagaaat tatgaaaaga ataattaaaa tatttggtgt
    31561 tttaggtgtt ttcttattag gtttaagtac ttttgttagt actggaacaa gtgtgtatgc
    31621 cacagaaaaa gtgaatacag ttgatttaga aataaagaat aaattagtag atgaattaac
    31681 tttttatttt gatacagttg gttttttaga cgaacatggt gtataccata taaaggattt
    31741 tggtgctatt cgtgaacgaa tcagtcaaga taacgaacaa ggaagagcag caagagtctt
    31801 ttatgaacat attattgttc ctagaatgga gaaagttgat tggaaacgat atgctggatg
    31861 tgtagccatt aattctcttc ctggaggagg agtggcttgg gctataggta cgcagggaga
    31921 ttttattgaa gcattaaaag cttttaattt tgaaaaagct gcggatttat tattaaaaat
    31981 tgcagaaaaa caattaggaa aagctgcagc taaagagtta gctaaggtaa atattgtagc
    32041 aggaattgca gcagctgctg ctagctgtgc attagagtaa aagtttatga aaagtttaga
    32101 acaagagcat atggctttta aacaagcaat gtttaaagaa aatatctatt taaaccataa
    32161 ctatattcgt gtttctaagg catgttcacc agtattgaat atgcttggag gtggaaatgg
    32221 attatatcat ttactgtttg tcgatgtttg ttggttaatt tttttaccag atgaactagt
    32281 tatagtcaat gaaaaaataa caagtaaaaa tgaagtgttt aattattctt
//
LOCUS       DAZKPE010000028        30787 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000028 DAZKPE010000000
VERSION     DAZKPE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.028"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(133..297)
                     /locus_tag="ACG930_001425"
     CDS             complement(133..297)
                     /locus_tag="ACG930_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518592.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            592..1920
                     /locus_tag="ACG930_001426"
     CDS             592..1920
                     /locus_tag="ACG930_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFQ0518593.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2122..2955
                     /locus_tag="ACG930_001427"
     CDS             2122..2955
                     /locus_tag="ACG930_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFQ0518594.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2971..3708
                     /locus_tag="ACG930_001428"
     CDS             2971..3708
                     /locus_tag="ACG930_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFQ0518595.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3863..4831)
                     /locus_tag="ACG930_001429"
     CDS             complement(3863..4831)
                     /locus_tag="ACG930_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFQ0518596.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5063..5896
                     /locus_tag="ACG930_001430"
     CDS             5063..5896
                     /locus_tag="ACG930_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFQ0518597.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5930..6769
                     /locus_tag="ACG930_001431"
     CDS             5930..6769
                     /locus_tag="ACG930_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0518598.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6795..7355
                     /locus_tag="ACG930_001432"
     CDS             6795..7355
                     /locus_tag="ACG930_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0518599.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7554..9275
                     /locus_tag="ACG930_001433"
     CDS             7554..9275
                     /locus_tag="ACG930_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFQ0518600.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9440..10582
                     /locus_tag="ACG930_001434"
     CDS             9440..10582
                     /locus_tag="ACG930_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFQ0518601.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10598..11809
                     /gene="thiI"
                     /locus_tag="ACG930_001435"
     CDS             10598..11809
                     /gene="thiI"
                     /locus_tag="ACG930_001435"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFQ0518602.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12382..13029
                     /locus_tag="ACG930_001436"
     CDS             12382..13029
                     /locus_tag="ACG930_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFQ0518603.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13158..13374
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13422..16067
                     /locus_tag="ACG930_001437"
     CDS             13422..16067
                     /locus_tag="ACG930_001437"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFQ0518604.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16377..17690
                     /locus_tag="ACG930_001438"
     CDS             16377..17690
                     /locus_tag="ACG930_001438"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFQ0518605.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17680..18333
                     /locus_tag="ACG930_001439"
     CDS             17680..18333
                     /locus_tag="ACG930_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0518606.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18388..19080
                     /gene="radC"
                     /locus_tag="ACG930_001440"
     CDS             18388..19080
                     /gene="radC"
                     /locus_tag="ACG930_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFQ0518607.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19230..19430
                     /locus_tag="ACG930_001441"
     CDS             19230..19430
                     /locus_tag="ACG930_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0518608.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(19684..21363)
                     /locus_tag="ACG930_001442"
     CDS             complement(19684..21363)
                     /locus_tag="ACG930_001442"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFQ0518609.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(21365..21577)
                     /locus_tag="ACG930_001443"
     CDS             complement(21365..21577)
                     /locus_tag="ACG930_001443"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFQ0518610.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            21970..23700
                     /gene="efrA"
                     /locus_tag="ACG930_001444"
     CDS             21970..23700
                     /gene="efrA"
                     /locus_tag="ACG930_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFQ0518611.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            23697..25457
                     /gene="efrB"
                     /locus_tag="ACG930_001445"
     CDS             23697..25457
                     /gene="efrB"
                     /locus_tag="ACG930_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFQ0518612.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            25552..25749
                     /locus_tag="ACG930_001446"
     CDS             25552..25749
                     /locus_tag="ACG930_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518613.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            25902..26387
                     /locus_tag="ACG930_001447"
     CDS             25902..26387
                     /locus_tag="ACG930_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFQ0518614.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(26491..27084)
                     /gene="clpP"
                     /locus_tag="ACG930_001448"
     CDS             complement(26491..27084)
                     /gene="clpP"
                     /locus_tag="ACG930_001448"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFQ0518615.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            27264..27791
                     /locus_tag="ACG930_001449"
     CDS             27264..27791
                     /locus_tag="ACG930_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518616.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            27882..28619
                     /locus_tag="ACG930_001450"
     CDS             27882..28619
                     /locus_tag="ACG930_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFQ0518617.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            28623..29540
                     /gene="miaA"
                     /locus_tag="ACG930_001451"
     CDS             28623..29540
                     /gene="miaA"
                     /locus_tag="ACG930_001451"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFQ0518618.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            29542..30771
                     /gene="hflX"
                     /locus_tag="ACG930_001452"
     CDS             29542..30771
                     /gene="hflX"
                     /locus_tag="ACG930_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFQ0518619.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10169 a         5266 c         6568 g         8784 t
ORIGIN      
        1 aaagcttatg caaagaaaaa gaaatccaat cacttgggtt tctttttctt ttattattat
       61 gatgaatcaa gctttctgtt tttgtcacgt atgttgtaat ctttacgaaa gagtagagtt
      121 ggctactcat aatcaaccat acttcccatc atcgctaaat acgaaataaa tcagcattcc
      181 tacaccaatc aaagcacaag ctgcaccaag aaaagggatg acattcccaa agttatctgt
      241 attcataagt atgccaccac ccacaaacaa aaagccgcca gcaatcaggt ttttcatttt
      301 attcatctcc tttcttacgt tatagtattt ccttctttca atgagtattt tgaaagctat
      361 cttattgtat gatgttcttc taggcctctt ctttattata caggccattt tcgttatctc
      421 atagaaatat tcctttttat ctgaaaacta ttgtataccg tatgacattt ttcttcatga
      481 agttgtaagt atattctcat tcaaatgaaa atttcatcat agaagagatt gtatttctaa
      541 attcttaaga gtaaaatacg aagtataact tggatttgga aggatgattg gatgaaagct
      601 attacgcctg atatgacaac aaaatttaac aaacagtttc aagcaaatat caaacagcag
      661 gcattgcagc gggcagttgt gaagaacgga attactgctt ctgctgaaaa tgtttcagca
      721 catgtggaga atacaccggt attttctata gatttggcta cggggaaagt ggctaatcaa
      781 atgcaatcgg ggcgttgctg gatgtttgct gcactgaaca cattccgtca taagatgctg
      841 aatcaattcc atttaaaaga gtttgaatta tcacaaaatt acactttttt ctgggataaa
      901 tatgaaaagg caaattattt ctatgaaaac atcattgcaa caggaaaaga ggcaatcgat
      961 agccggaaag tagctttctt actcgctact cctcaacaag atggcggcca atgggatatg
     1021 atcgtttcat tattccaaaa atatggcgtt gtgcctaaat cggtgatgcc ggaaagtgcg
     1081 aatagttcaa attctcgaga tttgaataac tacttgaaca aattactgcg taaagatgca
     1141 gtagtgttac ggaaaatggt tgctcaagga gaaacattag acgctattga agaaaagaaa
     1201 gaagaaatgc tagaaagcat ttataacttc ttagctatct cattaggaac acctccaaaa
     1261 gaattcgatt ttgagtaccg cgatgaagaa aagaactatc atcttgaccg aggactgaca
     1321 ccacaaattt tttatgataa atacatcggt gtaaaattag atgattatgt tagcgtgatc
     1381 aatgcaccaa caaaagacaa accattcaat cgttcttata cagtagagat gctaggaaat
     1441 gtcgttggcg ggaaagaagt caaatatctg aatgttgata tggaaacttt caaaaaatta
     1501 gcgattgctc agcttgaaga aggagaatct gtttggtttg gttgtgatgt aggtcaatct
     1561 tctactagaa ctagtggcat catggcctta gatgcttatt caatggatga tctatttgat
     1621 acggatttta caatgactaa agctgaacgt ttagattttg gagaaagtct gatgacccat
     1681 gcgatggtat tgaccggtgt tgacttagta gacgggcaat caacaaaatg gaaagtcgaa
     1741 aatagctggg gcgaaaaagt tggaaagaat ggcttctttg ttatgagtga tgcctggatg
     1801 gacgaatata cgtaccaaat cgttgtaaga aaagatttat tgacgaaaga gcaattaaat
     1861 gcgttcaatg aagaaccaat tgttctatct ccgtgggatc caatgggtgc tttagcatag
     1921 acgagtattt caatgaagag tatgtagtaa agataaaaag agctggctta agccagctct
     1981 ttttatcttt aaagtccatt ccctgttttt tatggtccct gtgctataat tctaaataaa
     2041 ggataaggat tggaaataat ccttttatca ttaaaaatat gatgacgaag tagaataaaa
     2101 ttgggagtag gggggaaagt catggatatc caaactgttt tatctgatct gaaattaaat
     2161 ggtaaagtga ttccagttgt tggtggcgat gttaatcaga cctatcgtat aaaaaccgaa
     2221 catcgtgctt attttttaaa aatccatccg aatgtaaaaa aaggattttt tgaagcagaa
     2281 gtagacggat taaaagaact gtcagcattc gtacgtgtac cggatacgta tatgctaggt
     2341 gaaacaagtg aaggcgctta tttgttaatg gaatggatcg agccgggaaa aggggatcaa
     2401 cgagatcttg ctgcagcttt agctaatctc catcagcaaa cagcgccaca atttggtttt
     2461 cgtaaagata actatttggg tacacttgtt cagaaaaatt cttttgaaga agattggtgg
     2521 acttttttct ttaaagatcg gcttgaatcc cagatttctt tggcagaaga aacgaatcga
     2581 tggaatgtac agcgtcaaga aaagtatctg cgatttaaag aacgtgtatt gaaatcggtt
     2641 gaaccaaaaa agatcactcc acgcctcttg cacggagacc tgtggagtgg taatgtgttc
     2701 tttgaccagc aagggcatcc agtttttgtc gacccagctg tttcttatgg gaatcgggaa
     2761 caagatattg caatgagcca gttattcggt ggtttccgac cggaattttt agatgcttat
     2821 caaactatat ttccattaga aaagggatgg aaagaccgac tgccgattta ccagttatat
     2881 tatcttttgg cacatttgaa tatgtttgga gaaagttacg gttcccaagt agatcaatta
     2941 ctagaaaatt tttaagagga gggcgtgttt ttggcaaaaa aatataccaa aaagcatgaa
     3001 gtttcatatt atgagtgtga catcaaccaa acgatgacat ttccttcgat gttaggagta
     3061 gttatcaaaa cgtctgaaga tcaaagcgac cagttgggaa gaggcagtga attcgtcaat
     3121 agctttggac ttacttgggt catcacgaat tattccatgg agattaatcg tctccctaga
     3181 gtcggtgaag taatctcagt aacgactcaa gccatggagt acaataagtt tttctgttat
     3241 cggaacttct ggatccatga tgaagatggg aaagaattag tcaaaataga atctgttttc
     3301 gtattgatgg attttgtgaa tcgaaaaatg agcagtgtta atgaagagat cattgctcct
     3361 tttgagagtg agaagatcaa gaaaatcaag cgtcaggaaa aaattgaaaa gattgattcg
     3421 ggcttcatgt tgccatatcg tgttcgtttt tatgatatcg atagtaatca gcatgttaat
     3481 aatgcgatgt attttaattg gatcattgac gtattaggat atgacttttt gactacgcat
     3541 gttccagaaa aagtaattat tcgatttgat aaagaagtag agtacgggaa tgagatcgaa
     3601 agccattttg aacaaatccc tatcgaaaat ggtgtcaaaa caaaacatga aatccgaatg
     3661 caagaacagc tgtattgtga agcaaatatt atatggaaaa ataaataaaa aagaggttgt
     3721 gacagaaggg ggcaacttca agaaataaga agaaatttac gaaaattgtt tctcaaattt
     3781 ttgtaaattt tcgacttagt tttcgaagaa gctatttttg tcacagcctc tctttttaag
     3841 tttagctatt agataatgat gtttagtttt ggataaacga aatcaattct tcacccgaca
     3901 aaccatagtt tacagcaatc aatagtttta aacgtgcttt ttgactatta atactgttac
     3961 agaaaataat ccccattttt tctagttctt ttcccccgcc ttcataatca taaacaggct
     4021 ctgcgattcc attgaaacaa cgagaaacaa gtactacagg gattttttgg acaagaagct
     4081 tttccaaagc agctaaggct tgtggaggga gattccccgc acctaaagct tcgattacca
     4141 aaccgtctac tttcgtatgg gcgatggctt ccaataagtc cccttgcatc ccagcatatg
     4201 ctttaacgat cgggatagtc ccatctacag cggaaatgtc cagtcgcttt gtttctaaaa
     4261 gttcctgcaa gaataaaatt cgattcttag ttactaagcc gatgggaccc aatgtaggtg
     4321 ttcggaaagt agcaacattt gtggtatggg tctttgtcac gtagcgtgca gaatggatct
     4381 catcgttcat gaccaccaaa acccccttat ctagcgcttc ttcacaactt gcgacacgaa
     4441 tcgcactttc aaaattataa aggccgtcac ttccaagttc attacttgaa cgcattgccc
     4501 cagtcaaaac aattggtaat ttgttgccaa tcgttgtatc aagaaaaaaa gcagtttctt
     4561 ctaatgtatc tgtaccgtgt gtgatcacca ctccggatat acctgatgca taagcggaca
     4621 agatacgttc ttttaatacc aacatgtgag aaggcatgat gtgtggtgag ggaagattga
     4681 agatatcttc aactaataat tctacatgct tggggattgt gatttctgca tctaataatg
     4741 ggtttgccac atcaggacta acaccgcccg tgagcatgtt ttctttcatg gcgatcgttc
     4801 cgccggtgtg tagtacaagt atttttttca ttttacagac ttccttacga ataattttgc
     4861 atagccgtta aatcttattg tatactatat aaaagagttt tgctatcagt gaagaataac
     4921 gaatagccta acttatcata aaaaagctga ccttattaaa atggaaaaga ctcaaccttg
     4981 acctcctaat acaatggagt atctggttga gtttctttta caagaaagca gccaaggaaa
     5041 tcaatcacga aggtggccgg aaatgatcag aatcggatta acatcgttta aagaacatga
     5101 caaattaact ggtaaaaaga ataacactct ttatgaatat gcagggtttc tacccttagt
     5161 ggaattagat actgcctatt atggaattcc ccgaaagtcc tcagttgaga attggataag
     5221 tgaagtacct gaatcatttc gctttgtagt caaagtctat caaggaatca gcggtcaagg
     5281 agactggaag ccttattatc agaccgaaga agagatgatt gcgcattttt tagatgttat
     5341 gtcgccaatg gtagatgctg gaaagatgtt ttgcttttta gtccaattcc cctcatcatt
     5401 caaatgtacg aaagaaaatg tccagtactt gcgcaaactt agaaagtggt ttgagggtta
     5461 tcctgtttct atagaattgc gggattattc ttggtacagc gatgaatttc ttgaacgtac
     5521 aagaaacttt atgtctagag ccgctttttc tttagccatc atcgatgagc cacagttgct
     5581 gaatacaacg attccttttg atccatttgt caccaatccg aactttgctc tttttcgatt
     5641 ccatggtagg aatgcgcaag gatggcaagc aaatgataaa gagtggcgta aaaaaagaac
     5701 gttatatcgt tattcagaaa aagaactgca agaactagca catgaagtca aagtagttga
     5761 ttctaagaca aaagaggtag gtgtgatttt taataataat tctggtggtg atgcggctga
     5821 aaatgcatta gcactgcaaa aaatattaaa tatcaagcca gatggactca atccaaccca
     5881 aatggatctg ttttaagggc ttattttatt caagaaaggg gcgaagtcta tgatcaaagc
     5941 tatttttttt gatattgacg gaacattggt caccaatcgt tcaaaagcgt tggaatcaac
     6001 aaaacaagca attgaatatg ctcggaaaaa cggcatttta tgcggtgtag caacggggcg
     6061 cagcccagta aagatcaaag aaatcattga tgaattggaa ttagatatgt atgtcgtgta
     6121 taatggtcaa ctggttttta ctgcagatcg cacgattatc gaccaccctt ttgaacaaaa
     6181 agtattggaa catattgttg aatttgcaga tgagaaccat cgacaaatcg tttttggtgc
     6241 gagaaatcgg ttagatggat caacgacgat gctattagga caatcgattt ttatcaagcg
     6301 actagtcagc tttttaccgc gtaaattccc ggtacgtctg atgaaaaaaa tcctccaggt
     6361 ttttagccct caccgacaaa aggatcgtta tgaaacgtta gagatattaa aagaaccaat
     6421 ttatcaatgt atattgctca gtccggagtc agaacagaaa aagttagaac atcgctttcc
     6481 cgagtgtacg tttcagcgtt caaatacgta tactgtagat atcatcccaa aaggtggttc
     6541 aaaattacta ggcatccaag ctttcgcaaa tgctgtcgaa attgaaatgg aagaaattat
     6601 ggcattcggc gatcattaca atgatatcga gatgctgaaa ggtgtaggaa ttggagtggc
     6661 catggggaat gctcagatcg aagtaaaaca tgctgcagac tttgtgactc aatcaaatga
     6721 agaagatggg atatacgaag gactgaaaca cttcggtctg atttattagt caatgaaaga
     6781 aggaaaaaat cagtatggaa gcagagacac cttttcaaaa agtagaaaca ttccacaaaa
     6841 cttttgatcc aagaagacca gagataccca cggcttttac agaaaatgaa gctcatacac
     6901 gtgctgcgtt caaaatagaa gaacttgttg aatttgttgc agctacttca cctaataaag
     6961 aacaactgca tgaagctgtt atgctgctgc acgaagcatt agataaagca gaagaaaaaa
     7021 tacttggtaa aacacagtgg ggaagtgatc cgctggttga acaagtagat gcactgacag
     7081 atatccttta ctttacttat ggttcttttt cattactagg aatagtgcct gatcgaatat
     7141 tcgaaatcgt ccatcaggca aatatgggga aattatttcc agatggaaaa cctcattatg
     7201 accctgtaac aaataaagtg ttgaaacctg aaaactggca gatggaatat gctccagaac
     7261 ctaaaatcgc ggcagaaatc caacgtcaga ttcaagaagc gattgctaag aagaaatccg
     7321 ctgatatagg catgtgcaca aatgaaaaag agtgatcaga gtttcactat ttttgttatc
     7381 tttatacgat ggaaaaacaa aagattttcg tttaagttag tgaatgcatg aaaatagtat
     7441 gctataatct agaatagatg tcttttgcac gagagacgta ttatttggat ttatgccaag
     7501 cagaacgcca tctgttgcat aaaagatgca tactgaaaac ggaggaacca taaatgggaa
     7561 ataatgttat catcggaatc gtcattgcaa tcattatagt cgccattgtc gtctttttgg
     7621 ttagttactt gatgaagaaa aaaaaccaag atcgattgga tgccttagaa aaacgcaagg
     7681 aagaattatt tgacttgcca gtgattgaag aagtcgatga tgttaaaaaa atgcatctgg
     7741 ttgggcaaag ccaaaatacc tttcgtgaat ggagtcaaaa atggaatgac atatctactt
     7801 cctcgttcgc tgaactagaa agtcaaattt tcgaagtgga aaacctcaat gaaagttttc
     7861 ggttcttaaa aggaaaaaaa gcagttgttg aagcagaagc tacaatggac caaatggaga
     7921 aacaagtgac ggaaatccgt gaaggtctaa aggaattgcg ggaaacggaa gaacgcaact
     7981 cactagctgt tcagcaggca cttgacgtct atgaagaact gaaagaaaaa gtcagagaag
     8041 acgagcatga atacggacca gctctttttg aattgcaaaa acagatcaaa gtgatcgaaa
     8101 aagaatttac gcagtttgtg actttaaaca cttctggaga ccctgttgaa gcccgcgagg
     8161 ttttggataa agcagaaaaa catacgtatg aagtggaagc tctgatgaaa aaaattccac
     8221 cgctgtatga ggagctccat accactttcc ctgaacaact tgaagaaatc agtgatactt
     8281 acgagaaatt gatggaagaa caatatgtat tcccagaaga agatcttgct gaagatatcg
     8341 caaaagtaag tcgaagaatt gaaaattcat tagccaatct tgaaaaaaca gaagttgaaa
     8401 cggtcgaatt tgaaaaccgt gaaacagctg atttgattga ttcgttatat gatatcttag
     8461 aacgggaaat ggaagctcag agatatgtaa aaactaacca atcaacgatt gcagagtata
     8521 tcaaacatac aacaaagaat aaccgtcaat tattgattga gctggatcac acatctcaaa
     8581 gctatacatt gaaccacaat gaaattggcc gtgtacgagg tttccaaacc gaagtggaag
     8641 aaatggaacg tcaaaatgaa cagatgattc cacagatccg tcaacacgaa attccttatt
     8701 cagaagtgcg cacgttctat aaaacagtct tcaaagtctt agaagatatc gaaaagcaac
     8761 aagtagagat cgacgactca ttacatgaat tgagaaaagg cgaaaaagaa gcgcaagaaa
     8821 agatcgatac attcgaattc aaattgcgca gtttgaaacg ttttgtagaa aaacaacgtt
     8881 tgcctggctt gccgaatgat tacctagaat tcttttttgt tgctactgac cgtattgaag
     8941 aactaagtgt tgtcttgaat aaaattcgag taaacatgga agaggtcaat cgtttagttg
     9001 ctctatgtga agaagatcta gaattattag ataagaagac acatgattta gtagatgcag
     9061 cagcattaac ggagcaaatg ctccaatatg caaatcgtta tcgtcataca cacgaagaag
     9121 tgagagaagc aattgataaa agctactatt tattcaataa agaatatcac tatcaagaag
     9181 cattagacga aatcggtaca gcattagagc gagtagaacc tggtgctttc aaacgcatcg
     9241 aagattttta ttttaatcat ccagacttag tataaagcaa aaaagttagt aaaccagcaa
     9301 gagcaagacg gattattgtc ttgttcttgt ctttttttgt atatttgaaa attgaaacaa
     9361 gtgaaaattt cacctgctct tgaaagcacc ttggacaacc gttataatag aaaagaattt
     9421 caaaaaagag gggtttctta tgatatattt tgataacagt gcaacaaccc caatctttcc
     9481 gcaaagctta gatgcatatg taaaaaccag tcagcggatt attgggaatc catcaagctt
     9541 gcatgattta ggcaatcaag ctaaccggtt gttgcagcaa gcaagaaagc agatcgctga
     9601 tttgatccat gtagaaccag aagaaatcta ttttacttca ggcggaacag aaggagataa
     9661 ctgggtatta aaaggaacga tgatcgaaaa aagagaatat gggaatcata tgatcatttc
     9721 aggagtcgaa catccggccg tcagcgagac agcagaacaa ttaaaagaat taggaatcga
     9781 agtaagtatc gccccagtgg ataaacgcgg atttgtacgt gtcgacgaat tgaaagaatt
     9841 aataagaaaa gagacagtat tagtctctgt tatggctgtg aataatgaag taggatcgat
     9901 tcagcccatc caggaaatca gtgatctttt ggatgatttt cctaaaattc atttccatgt
     9961 agatgctgtt caggcgattg gaaaagtacc attctcgcaa tggttgacag aaagagttga
    10021 ttttgcaaca ttttcagctc ataaattcca tggcccacgg ggaactggtt tcatttattg
    10081 gaaaaagggt cgtcgtttag caccattact gacaggtgga gggcaagaaa gaaatcagcg
    10141 aagtgggaca gaaaatgttc caggtattgt ggctatggtt aaagctttac gtttatcatt
    10201 agagataaag gaacaaaaac ctgagcagac acaacgctta aaagtagctc taatcaatgc
    10261 gttgaagacg tatgagaaag tgacgatttt ttcagaagga actgactatg caccgcatat
    10321 tttatgtttt gctctaaaag gaattcgcgg cgaagttctc gtccatgcct tagaagaaaa
    10381 acaaatattt gtttctacta ctagtgcctg ctcctcacgt aaacatatgg caagcagtac
    10441 attgcacgca atgcatgtac caaatgatct ggctacatct gctgttcgaa tcagcttaga
    10501 tgaaaacaat tcgcttgcag aagtcgagca atttatgatt attttcaagc agctttataa
    10561 gaaattttct gcaatcaatt aaaagaggag tgttcttgtg aaatacagtg aaattatggt
    10621 ccgttatggg gaactttcga caaaaggaaa gaatcgaaaa agctttatca tgcaactagc
    10681 acaaaatgtc agacaagctt tgaaagactt tccagaaatc aaaatccatg ctgatcggga
    10741 ccggatgcat cttttattga atggcgcaga cgggcagcta gttattccaa aactagcaaa
    10801 aatatttggg atccaaaatt tctctccaag tattcgtgta gaaaaagatg tcgaagtttt
    10861 gaaacaagct gttcaagaca tcatgaaaga aatttatact gggaaagaaa catttaaaat
    10921 tatcgctaaa agaagcgatc accaatttga attgacaagt aatgaattga atcaaacatt
    10981 aggtaatgct gtttttgata ttttcccgca tatccaagtt caaatgcgtc aaccagatat
    11041 tccattacgt gtagagattc ggcgtgatgg cgcttatcta tcgtatgaaa cgatcaaggg
    11101 agctggagga ttgcccgtag gaacaagcgg aaaaggaatg cttatgcttt ctggggggat
    11161 tgattctcct gtagcagggt actttgccat gaagcgggga gtggaaattg aagctgttca
    11221 ttttgctagt ccgccgtata caagtgaaca agcactgcaa aaagcaaaag atctaacagc
    11281 caaactagca ccttatgtgg gaacgatcca ttttatcgaa gtgccattta ccgagattca
    11341 agaagaaatc aaaaagtcag tgccacaagg atattggatg acaattactc gtcgaatgat
    11401 gttgcgtttg accgatgaaa ttcgccgtat tcgtcatggt ttagtcattt tgaatggtga
    11461 atcattaggt caagtggctt cacaaacttt gcaaagtatg gtggctatca atgaagtaac
    11521 gaatacgcca atcattcggc ctgtagcgac aatggataaa cttgaaatca ttgaagtagc
    11581 agaacagatc gatacattta atctttctat ccagcctttt gaagattgct gtacgatttt
    11641 tgctcctcca cagccaaaaa cacgccctca actggaaaag gtccatcaat atgaagagcg
    11701 tttagcaata gatgaaatga tccaacgagc actagctggc ttgaagatgg aagagataca
    11761 agcagaatcg tctaatgaaa aaactgaaga attttcagaa ttgctataag aggttatgaa
    11821 aatagtgttt tgaccagagt attagagaaa caaaacgaaa aaatagctcc atgtatttta
    11881 ccgtttttga actaatgtcg aagattagct gattgaatac catttatcaa gaagttatgg
    11941 aaaagccggt tcttttttac taactgaaaa ataaaatttt atttagagat caagctacag
    12001 ttgataaatg atataaaaaa gagaatttcc catgaaatag cgaggttgtg acagaagtgg
    12061 gcagcttcaa gaaataagaa ggaatttacg aaaattgctt ttcaaatttt tgtgaaattt
    12121 cggcttattt ttcgaagaag ttacttctgg aacaccgtgt atcagaggtt gcgaaaaagc
    12181 tgccctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatat tttacgtttg
    12241 gttgagctta ttaccgcaga tgcaagcttt tgaacaccgt tttatttgtc tcacaccctt
    12301 ttccttccta cttgtaacct tgctcccgtg ttagaaacat gttacactaa atatgtgaaa
    12361 ttattaacaa ggagcgtcgt tatgcgagaa aaaacagata cactgccaaa agcaactgcg
    12421 aaaagattac ctttatattt acgctacttg aagatgctgg atgactcagg tataagtaga
    12481 atcaaatcaa atgagttcag cgaaatcacc caaattcctt ctgcaacgat ccgcagagac
    12541 ttctcgcaat taggcgagct aggcagaagc ggatatggct atgatgtccc ttttcttatc
    12601 gatgtattca ataatatcct taatactaaa gaagaaaaac gaatcgcatt agtaggatat
    12661 ggaaatcttg gcaaagcatt gaaacacaac aattttagaa gaaatgaaaa tctaaatatc
    12721 gtgtgcgtct ttgataatga tccagcactg atcaatcgag taattgatgg agaaatgatc
    12781 tatccgattg atcgtttcgc ggagatagcc aaagcaaaaa atgtgacagt agcaatctct
    12841 acggtaccaa gtaaatattc acaatctgct attgatgaaa ttgtcaaagg aaatgtaacc
    12901 gctatactta attttgcgcc tgacagagta actgtcccag cttatgtcaa tgttcaatac
    12961 attgatttga caaccgagtt gcagacgctt atttactttg atgagaatta ctcagaagtt
    13021 ttttcttagg aaaatttgag taggcttatt gatcttgcga gaactcgtcg taattctttc
    13081 aaaaattttt tagtactaaa tgaagtggtt ttttcacgac cacttgttga ctaaaaaaaa
    13141 aaaccattgt agaatgaagc ataacgctga acaagaggag taactggcac attcattctt
    13201 agagagagaa ctatctgctg aaaggttctc aatgacaacc agtgaaggta gcttgggagt
    13261 ttctgtcttg aatggagtag agatagacga gtcgtgatcg ttaactcact tgagaggcaa
    13321 taatgattga ttattgcaat ttaggtggta ccgcgtaaat catacgtcct agaatacgaa
    13381 agtattttag gacgtttttt agtttaaagg aggaaaacag catgacggaa gaaaataacc
    13441 tatcaacaaa atataatccg caagaagttg aagctggacg ttatcagcat tggttagaac
    13501 aagatttgtt taaaccgagc ggagataaaa aagcaaaacc ttattcaatc gtaatcccgc
    13561 ccccaaatgt tactggaaaa cttcatttag ggcatgcttg ggatacgacc ttgcaagata
    13621 tgctgattcg tcaaaagaga atgcaaggat atgatacttt atggctgcct ggtatggacc
    13681 atgcaggaat cgcgacacaa gcaaaagtag aagcgaagct tagagagcaa gggatttctc
    13741 gttatgatct aggtcgtgaa aagttcatcg atcaagtgtg ggaatggaaa gaagagtatg
    13801 cgagccacat ccgcgaacag tgggctaaaa tgggcttatc tttagattac agtagggaac
    13861 gttttacatt agatgatgga ttatctgaag cagtacgtaa agtttttgtt accttatacg
    13921 aaaaaggttt gatttatcgt ggtgaatata tcatcaactg ggatcctcaa gcacgaacag
    13981 ctctatctga tatcgaagtt attcataaag atatcgaagg cgccttttat catatgagct
    14041 atgaactagc agatggatca ggcgtagtag aaattgcgac aacccgtcca gaaacgatgt
    14101 tgggagatac ggcgattgct gttcatccag aagacgagcg ttatcaagcg ctcatcggca
    14161 aaaaagtgat tctaccttta gtcaataaac aaatcccaat cattgcagat gaatatgtag
    14221 atatggaatt cgggacaggt gtagtaaaaa tcactccagc acatgatcca aacgactttg
    14281 aggtaggtaa tcgtcatgat cttccacgcg taaatgttat ggatgatgat ggtacgatga
    14341 atgaactagc aggaaaatat gctggaatgg aacgttttgc tgctcgtaaa gcaatcgtgc
    14401 aagatctgaa agaaatcggt cgattgatta aaatcgatac gatgatccac agtgtgggtc
    14461 attccgagcg gacaggtgtc gttgttgaac ctcggctgtc tactcaatgg tttgtaaaaa
    14521 tggcgccgtt agcgaaaaaa gccattgata accaagaaac agatcaagca gtggaattct
    14581 tccctccaag attcaatcaa acgtttttac gttggatgga aaatgtccat gattgggtaa
    14641 tctcacgaca attatggtgg ggacatcaaa ttcctgcatg gtatcacaaa gaaacaggtg
    14701 aaatgtatgt agggatggaa gcaccagcgg atagtgaaaa ctgggtacaa gatcctgatg
    14761 ttttagacac ttggtttagt tcagctttgt ggcctttctc aacaatgggc tggccagata
    14821 cggaaagcga agattataag cgatacttcc ctactagcac tttagtaacc ggttatgaca
    14881 tcattttctt ctgggtaagc agaatgattt tccaaagctt ggaatttact ggcgaacgtc
    14941 catttgagaa tgtcttgatt catggattga ttcgtgacga acaagggcgg aagatgagta
    15001 aatcattagg taatggaatc gatccgatgg aagtaatcga aaagtatgga gcagatgctc
    15061 tccgctggtt cttatcgaat ggttctgcac caggacaaga tgtccgcttc agctatgaaa
    15121 aaatggatgc ttcttggaac tttatcaaca aaatctggaa tgcttcacgt ttcgttatca
    15181 tgaatatcga aggaatgacc gtagaagaga tcgatttatc tggagaaaaa tcagtggctg
    15241 accggtggat ccttactcgt ttgaatgaaa cgatcgaacg agtaactgag ctatttgatc
    15301 gttttgaatt tggtgaagca ggtcgacaac tgtataactt tatctgggat gatttttgtg
    15361 actggtacat cgaaatgagt aaagaagtac tttatggaga tgatgctgtt tcaaaacaaa
    15421 ccacccgtag catcttagtc catacacttg atcagatcct acgtttattg catccaatca
    15481 tgccattcgt tacagaagaa atatgggaac atattcctca tcagggaaat tctctagtag
    15541 tggcagaata tcctgttgta cgtccagagt ttgatgatga aacagcttct aaagggatgg
    15601 aagtattgaa agaattgatt cgagccgttc gaaatattcg ttcagaagtg aatacaccat
    15661 tgtctaaacc aattacgttg ctaattaaaa caaacgatgc taaaatcgat caatttttag
    15721 ttgaaaatac aagctatatc gaacgcttct gtaatcccga agagttgacg atatcaagtg
    15781 agatcactgc gccagatcta gcgatgtcag ctgttctgac aggtgcagaa atcttcttgc
    15841 cgttagcagg attgatcaat attgaagaag aaatcaaacg attagaaaaa gaactggaaa
    15901 agtggacaag cgaagtaaaa cgtgtccaag gaaaactttc taatgaacgt tttgtttcta
    15961 acgcgccgga agaagtagta gaggcagagc gtgcaaaaga aaaagattat ttagagaagc
    16021 aaacggctgt caaagaacga atcgaaagtt tgcgtactat tcaataagaa tagaaaaaga
    16081 gagtgtgaaa tcagctagct attactaaaa gctagctgat tgaacatcgt tacaggaaag
    16141 agtttgagcc tcactcttag cttcgattca taaggagatg tgacataaat tttgtcgcat
    16201 ctctttttta gtctactctt attatgtagg agaaggaggg aggtggatca tgtatcaaga
    16261 gtcaataaag tagttgataa aatcgttcct ctctctgttt cttttctctt tgtcatactt
    16321 ttatttttct tatgtgttct atttgttata ataaaagaga aatgggggaa ttgttgatga
    16381 cgattgaaga agcaatagaa tggatccata gtcgattacc atttggttca cgtcctggcc
    16441 ttgaccgagt cgaagcttta ttagaagtgg tagggcatcc agagagaaaa gtaaaaacga
    16501 tccatatcgc tggaacaaac ggaaaaggtt ctactgtagc ttatttgaga agcctattag
    16561 aagaggctgg gctgacagta ggtacattta cttcacctta tatcgaaacg ttcaatgaac
    16621 ggatcgcaat caatggcaaa agcattccag acaatgattt gatccagctt gtaaaaaaat
    16681 atcagccact gatcaaacaa cttgatcaat ttgaagcagt agctggtatt actgaattcg
    16741 agacattaac agcaatggca tttgattatt ttttgatgaa gaaagtggac gtagcgatta
    16801 tcgaagttgg cttaggcggc ttattggatt ctaccaatgt agctgtacca atgctgacgg
    16861 gaataacaac gattggactt gatcataccg aaatacttgg agatacaatt gaagaaatcg
    16921 ctgcacaaaa agctggaatc atcaaacaag gcgttccagt agtaacagga aatattgccc
    16981 cagaagcttt tactgtcatc caacaaacag ctaaagcaaa aaatgcaccg ctttatgtat
    17041 acggggaaaa ttataaaata aactatctgc atcctgatga gatgtgggga gaagtatttg
    17101 aattttttaa tgaaatagga aagatccctc aattaaccac tccgctttta gggcaacatc
    17161 aagctgaaaa tgcaggagta gccatcgaat tgtattttgt ttactgtcaa ttggaaaagc
    17221 tgcctttccg agaaaaagat gttttgaagg gattgaagaa atctcgatgg ccaggaagaa
    17281 tggagcgttt gagtaacgag ccattagttg ttttagatgg tgcccataat acgcatgcaa
    17341 tgaaccggct tgttgagaat ttgaaaaaag aattcaaagg atatcaaatc aacattttgt
    17401 tttccgcctt acgaactaaa aatgttagag aaatgctaga acgattgcag caagtaccaa
    17461 atgtccatat ttatttgacg acctttgaac atccaaaagc catcgaatta agtgaagtat
    17521 cagatttagc aagtgagaga gtatcaatcg tttcattgtg gcaattcgga ttagcagata
    17581 tattggaaaa gatgacaaat gaagacgtat tagttgtgac cggttcactt tatttcattt
    17641 cagaagttcg ccatttatta atacaattag gaggagatca tgaagtataa tgcagtgatt
    17701 tttgacatgg atggtttgct gttcgacaca gagttagtgt attacgaagc cacacaagta
    17761 gtagcagaca agatgggttt tccttatgat aaagacctgt atttaaaatt cttaggtgtt
    17821 tcagatgaag aagtatgggc gaattatcat atgattttct cggaatttgg caaaacaagt
    17881 gtacaaagat tcatagatga ttcataccag gaaacgcttg aacgtttttc gcaaggagcg
    17941 gtacaaatga agcccggtgt gttggaactc ctctcttttt tagaagaaca tcagattccc
    18001 aaagttgtcg cttccagtaa ccaacgagca gtcattgaac ttttattgaa gaagaacaat
    18061 ctgtttgaac gatttgagac gattgtttct gcagaaaatg ttcaacgagc aaaaccagac
    18121 ccagaaattt tcttgttagc taatcagaag ctaggtacag cgaagaaaga aacattgatt
    18181 ttagaagatt cacaaaatgg tattttagca gcttctgcgg ctgagatccc ggtagtcatg
    18241 gtaccagatc tgcttccacc atcccaagaa ttgatcaaaa aaacagctgg ggttgtttct
    18301 tctttacatg aaatccctgc attgttaaaa taaaaatcca tctcttttcg tatcttattt
    18361 tagataagat agaaaggaga tgtttttttg ggaaaacgat tgatcaaaga agtacctact
    18421 agctctttac caagggaacg tatggaaatt tatggcgcgg aagctttatc ggatcaggag
    18481 cttttggcaa tcttactgcg taccggtcaa cacccttata gtgtgatgtc gattgctgga
    18541 aatctgttaa aaacgtttgg aggactggcc tctttacgac aggctacttt gcatgagtta
    18601 gaagagattc gagggatagg acgcgtgaaa gcaatcgaaa tcaaagcctt gatcgaatta
    18661 ggtcgacgaa ttcagacgga tcatgaaaga gcggctccac cggttcgtac cagctacgaa
    18721 ttggcccagc aattgattct ggaaatgaaa gatcacaaac aagaacattt ggtttgtatt
    18781 tatttggaca cgaagaatca agtgatctta aaaaaaacag tgttcatcgg ttcgctgaat
    18841 cagtcagtcg ctcatcctag agaaattttc cattatgctg tacgttattg tgcagcaagg
    18901 atcgttttag cgcataatca tccttctggt aatgttattc catcgcagca ggatatgaat
    18961 tttaccaaaa ggatacaaaa gtgtggagaa atgatgggga tcactgtact ggaccacttg
    19021 atcatcggac gcaaacgata ttttagtttg agagaagaag gaatgatgga agagaagtaa
    19081 gttgctttct tgcaaaaaaa atgaagcaag tgtacaatta tattgtaatt ttgtttggga
    19141 atagaagttg aaacatctgt tgcacctcta tcgtacacga gcaatgttac aatttaaatt
    19201 agtgcttttg gcacgaggag gatattatta tggaaaacgg aacagtaaaa tggttcaacg
    19261 ctgaaaaagg atttggattt atctcacgtg aagatggaag cgacgtattc gttcacttct
    19321 cagctatcca aggtgacgga ttcaaaacat tagaagaagg tcaagcagtg actttcgacg
    19381 ttgaagaatc agaccgcggc ccacaagctg caaacgttgt aaaagcttaa ttttatctgt
    19441 aaatcaaatt gatggtagac atcaattttt acgagagaac aaagcgagta acaaaaatac
    19501 ctgccacaag agacaatttc tcttgtggca ggtatttttt tgtatgaaaa agtaaataaa
    19561 tttaagaggc tatgaaagag ccaccttgta tcaaggaata agaacaaaca aaaatggctt
    19621 ctcatgtttt tcatttgttt tctcttatat tcaggacaag gtgctgattt cataacctct
    19681 tatttattct tcatctggtg tcattaccat tggcaaaatc attggatgtc tttctgtacg
    19741 ttcgaataag aaaggctgaa gcgcgccagt catcgcttct ttcaatttat attctgaaca
    19801 gtcaggtcca ttcaaacatt ctcttaaagc gtggaataag attcgctgag cttcattgat
    19861 catttctcct gattctcgca tgtagacaaa tccacgagag agaatatctg gaccagccaa
    19921 gatttctttt ttcttgatat ccactgtcgc gacagctaat acaagacctt cttctgaaag
    19981 caggtgacgg tcacgtaaaa cgacattacc aatatcaccg atcccgctac catcgatata
    20041 cacatctcca gccacaaaat gcccagcagg acgcgcagaa tcgctagtta acgctaaaac
    20101 atcgccattt tccatgatga agcagttttc tgcaggaaca cctacatctt gtgctagaga
    20161 agcatgtact ttcaacatgc ggaattctcc gtggacagga ataaaatatt ttggcttcat
    20221 caaacgaagc attaattttt gttcttcttg tccaccgtga ccggaagtat ggatgttatt
    20281 gatttttccg tgaatcactt ctgcaccagc ttcagacagc aaattgatca aatgattgac
    20341 acttgttgta ttaccaggaa taggtgaact tgaaaagatc actgtatcgt ctggctggat
    20401 ttggatttga cggtgagtac cattcgcgat gcggctcaac gcggccatcg cttctccttg
    20461 agaacctgta cataggatca tcgtttcatt ggcaggcaag cgattgattt cgtgtgcatc
    20521 tacaaatgtg ccgtctggaa ctttgatata tcctaaacgt tgaccgttga cgatggcatt
    20581 ttccatgctt cgtccgaaaa cagcgatttt acgaccagtt gccacagcgg catctgctgc
    20641 ttgctgcaaa cggaagatgt tagaagcaaa gctggcaaaa atgatacgtc cttcgatttt
    20701 tgaaaagatc ttcaaaatag aatgcccaat cgttttttct gatttagtaa atgttggaat
    20761 ctcagcattt gtactatcag ataaaaggca caagactcct tcttccccga tacgagccat
    20821 tttatgcaag tttgctggtt cgccaacagg agtgaaatcg aatttgaagt ctccagtcgc
    20881 tacgatattt ccagaaggtg ttttcaccac gatccctaat gcatctggga tactatgggt
    20941 cgttctgaaa aagctgacag aagtctttct aaaacggatg atcgtatctt cattgatctc
    21001 atggagctct gcatctcgaa gcaagccatg ctcatctaat ttgtttgtga tcaacgctaa
    21061 tgcgagagga ccagcataga taggaatatt tgcttgtttc agcaagtagg gtattccgcc
    21121 gatgtggtct tcgtgcccgt gagtaatcac caaggctttt actttgtgta agttttgtat
    21181 gatgtagctg tagtcgggaa tgacatagtc aattccaagt aaatcgtctt ccgggaattt
    21241 gatcccggca tcaatcaaaa tgatttcatc ttggaattgt accccatacg tatttttccc
    21301 gatttcacct aatccaccaa tagcaaagac gcctgtctcg ttatttttga tggaaagttt
    21361 catattaaaa ctccactaat gagaaatcag cattttcttt ttcgtactct agatgacttc
    21421 cttctagaag ttgaacgaat tcaatattgt atggggtatt ttcttccaca cgttggcgag
    21481 cgtctacatc gctttttgcc tcaatgtaaa gagattttgt ttcttcccgt ttagggttgc
    21541 gtacttttgt ttcttgataa taaactttat agatcattgt tttgtctcct ttatctgcgt
    21601 aaagcagtga tttagctagt tgattttttt agacaacaca aaacgagggg acaagccacc
    21661 tggtttttca tatgctttga ctagaatact ggattcgagt caaagagaca agcctcgttt
    21721 ttgcttatct gttcggatat tttttcaacc gtaccttctg tataaaaaat atacaacaat
    21781 taattgttat tctagcataa aacagcaaat aagtatagaa atcaactaga ttgaaagaaa
    21841 aaatcaatgt ttatcatccc gctataatca taatgacttt tttatgagag aagtgttcta
    21901 ttaataggct cgttgtgcta tcatttttag taatgaaaat gtaacaaaag attaaaagga
    21961 gatgagaaag tgaaactaat gtggcattat accatgcgtt ataagaaatt cttgtttttc
    22021 aatttcatat gcgtatttgg ttttattttg attgaattag gacttcctac gattttagca
    22081 cgtatgatcg atgtaggaat ccgcaatgat gattttgatt atgtgaagca acaagggata
    22141 tttatgatcg ttattactgt aatcggtatt attttgaata tcttgttagg ttattttggt
    22201 tcgaggatta cgactaatat cgtagcagat attcgagatg atttgttcga aaagatccaa
    22261 agttattcgc atcaggaata cgaaaatcta ggcgtatctt cattgatcac tcgtacaaca
    22321 aacgatgctt atcagatcat gttgttcctg caaaatattt tacgtatcgg ttttatggca
    22381 ccaatgatgt tcattgtcag tttgtacatg gtcatgcgta caagtgtgac actcagtttg
    22441 tatgtagtag gtgcattacc tttactatta ttggcagtcg tagcgattgc taaggtgtct
    22501 gaaccgttat ctaaaaagca acaaaaaaac ttagataaaa tcaacagtat cttgcgggaa
    22561 aatctttcag gattgcgtgt gattcgtgca ttcgtcaatg aaaagtttga agaaaaacgt
    22621 tttgctgtag tcaatgagaa ttatgcttct agttcaaaaa gcttattccg tttgatggct
    22681 gttgcacaac cgggttttta tttcttattt aatatcgtaa tggtattgat catctggagc
    22741 ggggcagtgc aaatcgatgc aggcgagctt cgtgtaggag atttgattgc gtttatcgag
    22801 tatatattcc atgccttgtt ctcattcatg ttatttgcta gtgtgttcat gatgtatcca
    22861 agagcagctg tttcagctgg acgtatccaa gaagccctag atgccaaacc ttcgattgta
    22921 gaagatccaa atggtatatc tgatacaaaa actaaagggt atatcgaatt tcaaaatgta
    22981 acatttgctt atccaggcca ttcgcaagag ccagtgatac gaaatgtcag ttttacagcc
    23041 tctccaggag agaccgttgc ttttattgga agtaccggta gcggaaaatc tacgttgatc
    23101 caattgatcc ctcgctttta tgatgtgagt gaaggaaaga tcttgatcga tggagtagac
    23161 gtgagagatt atcggctaag caagttgcga gataagattg ggtttattcc gcaaaaagcg
    23221 ctgctattta ctggaacgat tgcagataat ttgcgatacg ggaaagaaga tgctacgcaa
    23281 gaagaaatgg aacgtgcagc tgagattgct caagcttcag aattcatttc tcgaaaacca
    23341 gatggattta atgaacattt atcagaaggt ggttccaatt tttcaggtgg acaaaaacaa
    23401 cgattggcaa tagccagagc catcatacgc cgtccggaaa tctatatttt tgatgacagc
    23461 ttttctgcat tagattatca aacggatgcg aagttacgtg ctcgtctgaa aaaagaaacg
    23521 acagaatcta ctgtattgat cgtagcacaa cgtgtgggaa cgatcatgca tgcagataag
    23581 atcatcgtat taaatgaagg agaagtcgtc ggtatgggga cgcatcggga gttgttggaa
    23641 aaatgcccga tttattatga tattgccgct tctcaattat caaaggagga attagcatga
    23701 aaaaaacctt ttcttcctta aaacgtttag ctcgatatat cagaccgtat cgtgagactt
    23761 ttcttttagt gatcctattt acagttctga cagtggcttt caacgtggct ttgccatatg
    23821 ttacaggact tcctactaca gaaatcagcc gtaatattgc caatggcgaa tcaatcaatt
    23881 tttcttatat attcaaatgt ctcatttgga tcacagttgt tggaataggg tattgtattt
    23941 cgcaattact ttctggtgtt ttgatgacaa atgtcgttca aagtgccatg catgatttga
    24001 gaagagacat agaagaaaaa atcaatcgtc ttccggtttc atatttcgat aaaaaccagc
    24061 aaggaaatat tttgtctcgt gtgacgaatg atgtagatgc agtcagcggt gctttacaac
    24121 aagcttttat tggtatcgta aatgcgatat tgggaattac gttggctgca gcaatgatgt
    24181 tttatatcca gccgatgatg gcgctgatct ctatgatcat gattccaaca tcgatctgga
    24241 tctcaaaacg agtgatcaat gcttcgcaga aatattttca aagcatgcag aattctcttg
    24301 gtgagctaaa cggctacgtc caagaaaata tgacaggttt tagtgtattg aaagtatatg
    24361 gacgcgaaaa agaaacattg gaaggattca aaaaagttaa tcacagcttg aaatactttg
    24421 ggtttcgtgc agcattcatt tctggcttga tgatgcctct agttcaatta actgcctatg
    24481 ctacttatat tggtatggct gttctaggaa gcttttatgt tattactggg gcgatcgttg
    24541 tcggtcaact acaagcattc atccaatata tttggcaaat cagtcagcca atggggaacg
    24601 tgacacaatt gtcttcagtt ttgcaaagtg catcagcggc aacgaaacgt gtattcgaga
    24661 ttttagatga gccagaagaa aaagaaaaca aagtagatgc ttcactgcca gaaacgattt
    24721 taggagatgt gacattcgat catgtcgatt ttgcatatga tccgaagaaa ccattaatcc
    24781 aagatttgaa ttttgaagtg aaagctggtc aaaccgtagc tgtggtcggt ccgaccggtg
    24841 ccggcaagac gacattgatc aatctattga tgcgttttta tgacgtagac aaaggagcaa
    24901 taaggattga tggaatcgac accaaatcaa tgagtcgcag tgatgtgcgt tcgctatttg
    24961 gtatggtctt gcaagatgca tggctttatc aaggaacgat tgcagataat atccgcttcg
    25021 gaaagcttga tgcgacagat tatgaagtag ttgatgctgc gaaaacagca aacgtagatc
    25081 attttatccg aacgatgcca gatggatatg atatggccat caattctgag ggagacaatg
    25141 tgtctttagg acaaaaacag ttgctgacga ttgcccgagc agtggtctcc gatcctaaaa
    25201 tcttgatttt agatgaagca acaagttcag tagacacccg tttagaagcg ttgattcaaa
    25261 aagcaatgga tcgcgtgatg gagggacgga caagtttcgt catcgctcac cgtttatcga
    25321 caatccgtga tgcagatctg attctagtga tggatcaagg tcagatcatt gaaaaaggaa
    25381 cgcatgagag tttattggca caaggtggat tttatgaaaa actgtataac agccaatttg
    25441 ctgaggaagc agaataagtc atataagaat aaaacagttt aaaacttatt ttttgttctc
    25501 tattcttgat aatggtaaag taaagttatc aagaaaagtg aggacacgga gatggaacag
    25561 tttttaaatg aaaaaattac tgaagccaaa agagaagttg atcgtttaac gcacgtctgt
    25621 cagacgaagc cttttgattc agctgatttt tttgaaaatg agtttcaaat cgaacgcttg
    25681 gcagcacaaa tagaagtgta cgaattaatt ttaaaaaaag taatagaaga aaatatagat
    25741 gtacaataaa aacaggtaaa acgtcagtta ccagatactg taaatagaca tctggcctga
    25801 gcaggtttta cctgtttttt ttcttatgaa ataaatatat gctatgatac ctttattcaa
    25861 taggattagt ttctacaaaa aatgaaagga gaaaaataaa tatggaacgg tttatagcat
    25921 caaatgccac agtgattggt gatgtgacat tgtcagaaga tgtgacgatc tggtatcaag
    25981 ctgttttacg cggggacagt aattggataa aaataggaca aagaacgaat atccaagatg
    26041 gtacaatcat ccatgtcgat catgatgcac ctgtagatat tgcggagaat gtgacggtag
    26101 gacatcagtg catgctacat ggctgtacaa tcgaaaaagg ggcgctgatc gggatgggga
    26161 ccacgatatt gaatcatgcg gttattggtg agaatagttt gattggtgct ggatcattag
    26221 taacagaagg aaaagttatt cctcctaatg tcttggcttt tggtcgccca gctaaagtga
    26281 tccgtccttt gacaaaagaa gaaatacaaa aaaacaaaga aaacatccag cattatgtcg
    26341 agataggtcg gatgcatgcg caaggaaaat tcaaggagca aagataggca gtagcatcca
    26401 taaaataaaa aaggatggtc agtttgagtt gaccatcctt ttttatttgg tttagataag
    26461 agagcttaaa aaagcttcct ttgaaacaga ttaatttaat gaagaactgt tttccatgac
    26521 ttcatcgatc aatccatatg cttttgcttg ttcagctgtc atatagttgt cacgatctgt
    26581 atctttttca atcacttcaa gcggttgtcc agtgcgttca gctaaaattt tgtttaagcg
    26641 ttcgcgtgtt tgcaaaatat ggcgtgccgc aatttcgatt tcagttgctt gcccttgagc
    26701 gccgccaaga ggttgatgga tcatgatctc agcatttggt aaagcaaatc gtttaccttt
    26761 tgtaccagct gtcagcaaga agcttcccat tgaagcagcc atacccataa caattgtttg
    26821 gacatctgct ttgacaaagt tcattgtgtc gtaaatagcc atacctgctg taactgaacc
    26881 accaggagaa ttgatataaa gatagatatc tttttcagaa tcttgagcgt ctaagaaaag
    26941 caattgggcg atgatcgaat tagcaagatc atctgttact tggccgctta acatgatgat
    27001 acggtctttc aataaacgtg agtagatatc gtaagctctt tcacctcgtg aagattgttc
    27061 aatgactgta ggaattaaat tcataataga gttcctcctt gatttcgttt agaaatagtg
    27121 taccataatt tagtttctaa tacctaaaat gtagtataca tttttggtca aaaaaggtca
    27181 aataaaaaac ttaggcaaat tagtcgcata aacccgcttt atggtatgat aagcagagaa
    27241 acaaaacaag gaggaacaac agattgatag ttggtattac tggccttatc ggagtgctga
    27301 caggtgctgt agttgtctat atcggcatga tactgcaaat gcgtcacttg gaaaataaag
    27361 aacagcgtag acgtgaattg gaattgaaag tcaaagaaat cgagacgctg aatcaattaa
    27421 ataaaaagat caacgagatc ttgcaaaaac ggacaacgct gatggaagaa tatgtcagct
    27481 ttgatgcatt tgatgattgt tatatcacga ttgacgattt tgcgtatctc caatcatttt
    27541 cagcgcaaaa tagtttttat ctgccaaatt atattttaga cgagctattt aagaatatct
    27601 cccatcgaaa agtgatttta tctccagatg aaacaatgaa gattggtgga tatgcttata
    27661 aaggcggacg cgtgatttta gagaatttta cggatagtct gactgaaatg atcaatgaaa
    27721 aaaaagctca gttgaagact atgacgcgcc agccgattgg tttcttctcg aaagatgatg
    27781 tttggagctg atattttgaa gcattgccgt tgcacatgag agcgtggtaa tgctttcttt
    27841 ttttcttaat gatacaatag aactgaacgg agtgaagaaa gatgttacaa atctatgccc
    27901 atcgcggaag cagcggcacc cacccagaaa atacgcttcc tgcatttgca gaagctgtac
    27961 gagtaggtgc agatggtatc gaactagatg tccatctaag caaagatggt tatttgatcg
    28021 ttatgcacga cgaagaagtg gaccggacga ctaacggtaa agggctgatt cgagaaaaaa
    28081 cattggaaga actcaaaaaa ttgaatgcag ggggcaaatt cagcaaagaa tttccagcag
    28141 ctaaagttcc tgaattgaga gaagtgttag gactgctcct ccaaaaaaat taccgaggga
    28201 tgctaatgat tgaaattaaa actgatcagt atgaatatcc cggtatcgaa gaaaaattag
    28261 ccgaaacatt aaaaagtaga gattggcctt ttcaacatgc atattgcagc tttcatttgg
    28321 attctttgga aaaaatcgca ttactggaac cggagataca gctggactta ttgatgagta
    28381 cttctgataa aaagatccaa ctagcagcag aaacccctta tatagaagga gtacatccaa
    28441 aaaatacttg gttgttcgaa catccagtcc aggcagctga ttttccaaaa gcaattcgtg
    28501 catggacgat taacgatgaa gaagaaatgg ccaaatgtca agaactcaaa atagatggaa
    28561 taataactga ttttccggag aaagctcttc ggtggaaaca atcaacgaaa agtaggtaaa
    28621 atatggaaaa agtattagtg atcgtcggtc cgacagcagt cggtaaaaca gcgctaagtg
    28681 tggaactcgc acaactattt ggaggagaga tcatcagtgg tgattcattg caaatctata
    28741 aaaatctgga tatcggtaca gcaaaaatca aagaagaaga gatgaataat gttccgcatc
    28801 atttgattga tgtgatcgaa cctactcaac gttactcagc cgctgatttt cagcattcag
    28861 gtcgacaatt gattaccgag attgcgaacc gagggcacct acctatcata gctggtggta
    28921 cgggtctcta tatccaatcc cttctatatg attatcagtt aggagcgaca gaagaagcga
    28981 atcctgagat tagaaaaaag tatgaaacgt tagctgaaac aattggttcc caagcattat
    29041 ggaatcagtt gaaagaaaaa gacccggcag ctgctgagaa aatccactgg aacaatcaac
    29101 gcaaagtgat aagagctctg gaagttttag agacgacagg acatagtatc acggcaccta
    29161 aagaagagcc aaagcaattg tatgattacc tcatgattgg attagatacg aagcgtagta
    29221 ttctttatga acgaatcaat caaagagtcg atttgatgct agcagaaggt ttagtagcag
    29281 aagcgcgtaa ggtgtatgag cttggagaag tccaggccag tcaaggtatt ggatataaag
    29341 aatttttccc ttattttgaa gggaaagaaa cattggaaga agcaacagaa caagtcaaac
    29401 tacattcgag aagatacgcg aaacgtcagt tgacgtggtt tcgtaaccgt ttggatgcac
    29461 agtggtttga tcttataagt gagccaaatc aaaaaagtca gattgagcaa acaatcaaaa
    29521 aatggctgga ggcggaataa aatggaagaa aaagtgatca tcgtaggggt agaaaccgaa
    29581 gcaaaccagc gttacttttc agagtcaatg gaagagctag ttcagctgac gaataccgca
    29641 tcaggagaag tcgtattcac aattacacaa aagagaccac aagtggatcg gcaaacgatt
    29701 atcggtaaag ggaaattaca agaattagtt caacaagcgg atgcgcatga agcggatttg
    29761 atcatcttta atcatgagct aactccgaga cagagccaac tgattaccga tgctgttggt
    29821 cttccggtaa ttgatcgcgt gcagcttatc ttagatattt ttgcgatgcg tgctcgttcg
    29881 aaagaaggga agctgcaggt tgaacttgct cagttagaat acctgctgcc tcgtttagta
    29941 gggcaaggga aaacattatc tcgtcttggc ggtgggatcg gaacaagagg gccaggtgaa
    30001 acaaagttag aaacagaccg ccgacatata cggaataaaa tttttgctgt taagaaagaa
    30061 ttgaaagaag tagaagctca tcgagagcgc aatcgccaaa aaagaaaaaa tagcgagatt
    30121 tttcagattg gacttattgg ctacacgaat gccgggaagt caactatctt gaatctattg
    30181 acacaagcgg atacttattc gaaagatcaa ttgtttgcaa cgttagatcc attgactaag
    30241 agatggcgtt ttgctgaagg atttgagatt actgtaacgg ataccgtcgg gttcatccaa
    30301 gacctgccta cgcaactgat cgatgctttc cattctacat tagaagaaag tcaaaatatg
    30361 gatcttttgc tacatgtagt cgatgctagt tctccagatc gtattttaca ggagcagact
    30421 gtcttaaaat tgatggatga actgaatatg aaagaaatgc cgatactgac tgtttacaat
    30481 aaggcagacc agatcgaccc agcgatgttc acgcctacgc tattcccaaa tgtattgatt
    30541 tctactcaga cgaaagaagg taagatggcg ttgatcgaag caatcaaacg tcagctgatg
    30601 gaactaatga ccccttatac actttctgtg ccaagcaacg aaggacagaa attaagcgag
    30661 ttgagaagac aaacaatggt tttggacgaa gcgtacatgg aagaaacaaa cgaatatgaa
    30721 gttaaagggt ttgcaaaaac caattcaaaa tggttaagaa aaaaccaata aaattttatt
    30781 tttttaa
//
LOCUS       DAZKPE010000029        30588 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000029 DAZKPE010000000
VERSION     DAZKPE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.029"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..428)
                     /locus_tag="ACG930_001453"
     CDS             complement(<1..428)
                     /locus_tag="ACG930_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFQ0518620.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKH"
     regulatory      complement(452..496)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            711..1679
                     /locus_tag="ACG930_001454"
     CDS             711..1679
                     /locus_tag="ACG930_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0518621.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            1776..2069
                     /locus_tag="ACG930_001455"
     CDS             1776..2069
                     /locus_tag="ACG930_001455"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518622.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2187..2423
                     /gene="secG"
                     /locus_tag="ACG930_001456"
     CDS             2187..2423
                     /gene="secG"
                     /locus_tag="ACG930_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFQ0518623.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            2526..3281
                     /locus_tag="ACG930_001457"
     CDS             2526..3281
                     /locus_tag="ACG930_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0518624.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3284..5641
                     /gene="rnr"
                     /locus_tag="ACG930_001458"
     CDS             3284..5641
                     /gene="rnr"
                     /locus_tag="ACG930_001458"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFQ0518625.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            5663..6127
                     /gene="smpB"
                     /locus_tag="ACG930_001459"
     CDS             5663..6127
                     /gene="smpB"
                     /locus_tag="ACG930_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFQ0518626.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6429..7148
                     /gene="atpB"
                     /locus_tag="ACG930_001460"
     CDS             6429..7148
                     /gene="atpB"
                     /locus_tag="ACG930_001460"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFQ0518627.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7201..7416
                     /gene="atpE"
                     /locus_tag="ACG930_001461"
     CDS             7201..7416
                     /gene="atpE"
                     /locus_tag="ACG930_001461"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFQ0518628.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7507..8031
                     /gene="atpF"
                     /locus_tag="ACG930_001462"
     CDS             7507..8031
                     /gene="atpF"
                     /locus_tag="ACG930_001462"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFQ0518629.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8018..8560
                     /locus_tag="ACG930_001463"
     CDS             8018..8560
                     /locus_tag="ACG930_001463"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFQ0518630.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            8583..10139
                     /gene="atpA"
                     /locus_tag="ACG930_001464"
     CDS             8583..10139
                     /gene="atpA"
                     /locus_tag="ACG930_001464"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFQ0518631.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            10153..11055
                     /locus_tag="ACG930_001465"
     CDS             10153..11055
                     /locus_tag="ACG930_001465"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFQ0518632.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11078..12484
                     /gene="atpD"
                     /locus_tag="ACG930_001466"
     CDS             11078..12484
                     /gene="atpD"
                     /locus_tag="ACG930_001466"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFQ0518633.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12498..12920
                     /locus_tag="ACG930_001467"
     CDS             12498..12920
                     /locus_tag="ACG930_001467"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFQ0518634.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            13389..13619
                     /locus_tag="ACG930_001468"
     CDS             13389..13619
                     /locus_tag="ACG930_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFQ0518635.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            13716..15017
                     /gene="murA"
                     /locus_tag="ACG930_001469"
     CDS             13716..15017
                     /gene="murA"
                     /locus_tag="ACG930_001469"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFQ0518636.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            15030..15206
                     /locus_tag="ACG930_001470"
     CDS             15030..15206
                     /locus_tag="ACG930_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFQ0518637.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            15341..15637
                     /gene="yidD"
                     /locus_tag="ACG930_001471"
     CDS             15341..15637
                     /gene="yidD"
                     /locus_tag="ACG930_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFQ0518638.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            15701..16168
                     /locus_tag="ACG930_001472"
     CDS             15701..16168
                     /locus_tag="ACG930_001472"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518639.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            16253..17137
                     /locus_tag="ACG930_001473"
     CDS             16253..17137
                     /locus_tag="ACG930_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0518640.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            17251..17487
                     /locus_tag="ACG930_001474"
     CDS             17251..17487
                     /locus_tag="ACG930_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFQ0518641.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            17575..17655
                     /locus_tag="ACG930_001475"
     tRNA            17575..17655
                     /locus_tag="ACG930_001475"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17609..17611,aa:Tyr,seq:gta)
     gene            17662..17733
                     /locus_tag="ACG930_001476"
     tRNA            17662..17733
                     /locus_tag="ACG930_001476"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17694..17696,aa:Gln,seq:ttg)
     gene            17859..18029
                     /locus_tag="ACG930_001477"
     CDS             17859..18029
                     /locus_tag="ACG930_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518642.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            18249..18956
                     /locus_tag="ACG930_001478"
     CDS             18249..18956
                     /locus_tag="ACG930_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0518643.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(19015..19659)
                     /locus_tag="ACG930_001479"
     CDS             complement(19015..19659)
                     /locus_tag="ACG930_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFQ0518644.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            19786..20073
                     /locus_tag="ACG930_001480"
     CDS             19786..20073
                     /locus_tag="ACG930_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518645.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            20181..20501
                     /locus_tag="ACG930_001481"
     CDS             20181..20501
                     /locus_tag="ACG930_001481"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0518646.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            20582..21895
                     /locus_tag="ACG930_001482"
                     /pseudo
     CDS             20582..21895
                     /locus_tag="ACG930_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            21892..22611
                     /locus_tag="ACG930_001483"
     CDS             21892..22611
                     /locus_tag="ACG930_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFQ0518647.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            22739..23290
                     /gene="raiA"
                     /locus_tag="ACG930_001484"
     CDS             22739..23290
                     /gene="raiA"
                     /locus_tag="ACG930_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFQ0518648.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            23512..26046
                     /gene="secA"
                     /locus_tag="ACG930_001485"
     CDS             23512..26046
                     /gene="secA"
                     /locus_tag="ACG930_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFQ0518649.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            26172..27273
                     /gene="prfB"
                     /locus_tag="ACG930_001486"
     CDS             join(26172..26243,26245..27273)
                     /gene="prfB"
                     /locus_tag="ACG930_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFQ0518650.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            27378..28064
                     /gene="ftsE"
                     /locus_tag="ACG930_001487"
     CDS             27378..28064
                     /gene="ftsE"
                     /locus_tag="ACG930_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFQ0518651.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            28057..28941
                     /gene="ftsX"
                     /locus_tag="ACG930_001488"
     CDS             28057..28941
                     /gene="ftsX"
                     /locus_tag="ACG930_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFQ0518652.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            29093..30541
                     /gene="cls"
                     /locus_tag="ACG930_001489"
     CDS             29093..30541
                     /gene="cls"
                     /locus_tag="ACG930_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFQ0518653.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT        10194 a         5287 c         6671 g         8436 t
ORIGIN      
        1 atatgtttcc caatatttgg gttgactttc aaagcagaag cgatattggt caaaggaccc
       61 aaagcaatga ctgatgtatt tgtcttttct ttgaaataat cagccaaaaa atcaacggca
      121 tggagaggtt ctgcctgttt tctcaagatc atcgggaaat ttgtttcccc taaaccatcc
      181 ataccatgag tgtcttgtgc actgatgaaa ggttgcttca aaggtttttc cattccttga
      241 taaacaggaa tgtctaaacg atcacagcgt tccaggcatt tcagcacatt ctgcgtacct
      301 atatctgcag ggacattccc acaaactacg gtaatagcaa ctacttcgat atcaggggat
      361 ttgacagcta atgataaagc taaagtgtcg tcgatccctg gatcgcaatc aataattact
      421 tttcgcatta tttccaatct cctttcttta gagatactta gttttttatt ctgggaagtt
      481 tccgaaccag tccaagacga gcgtcttgat tataatgcac gaaattagta tactggcttt
      541 tattgcgaat gtaaatgctc tcttacaagt aaatctattg aggagaactt taagtaaatg
      601 atacaatgaa aaagaaatgg aatttacgtg tgccgaaaat aaagaatcct atggatcggt
      661 acattggata atagatagat tatagtttgg cagaaagcgg cgggtgtaca atggttattt
      721 tttatttcat tcttattctg ataattatag ggatcagtta ccattttctt tcttattttt
      781 atgcaaagaa attagtaaga gcgggagtac agagaggata tgactggtat gaagacactg
      841 gtcatcgttt gatggaccct gctgcagtca cgtcagtaga aaaaaaacga caaaaattag
      901 aagaagagtg tgaaagcttt tgggagcagg gaacacccaa aacaatcaaa agttatgacg
      961 ggttgaaact agctggtcag atgttcatcc atccaaataa gcagaataaa tgggtcattt
     1021 gcgtacatga ttaccgaagc acagggaaaa gagacatgtc tcatataggt aaaagatatg
     1081 cagagaaagg attcaacgtt cttgtacctg atttacgtgc gcacggagaa agtgaaggag
     1141 aaatcatcgg aatgggatgg ctagatcggc tagatttaat tgcctggatc caactcatct
     1201 tagatgaaca gccgaatgcg tccattattt tacacggcgg atcaatggga gcttctacga
     1261 tcatgatggc aagtggtgaa aaacttccat cagcggtcaa aggatttatt ttagacagcg
     1321 gatatgtttc tgtttatgca gaattccgat atatgttaag taaaatcact gtctttccta
     1381 aaaaaatggt catgagatat gcgaatcatt atgcccagaa atacgccggt tactccttaa
     1441 agcaagcatc agctacgaga cagcttggca gcaatcatct gcctttatta gtcatccatg
     1501 gtgaaagaga tcattttgtc cctacagaag cagcgtacac gattcaaaat gctacggcag
     1561 gggataaagc actgctgctt gttccggaag cagaacactt ggaagcatcg atgaaagatc
     1621 cgaaaaccta ttggacagtg attttttcat ttattgaaca aagaataacg atgaattaat
     1681 tttctcttct tttttgtaag taattcgagg ataaataatt gtttatagat caggagactg
     1741 ctaaaataag gtaggaataa aaaaatatca gttatttgag gagtgcggca tatggaaatc
     1801 aaagaagaaa aaatcgtctt gctttattca atgatgaaca acaagagatc ggagaaatga
     1861 catggtcaga tgcgggccca gacatcatga tcgttgacca tacatttgta gatccagcat
     1921 atcgtggtca aaagttagct gaaaagctag tgtatactgg agtagaatta gcaagacgag
     1981 acgggaaaaa gatcattcct ttatgccctt atgcaaaaaa agagtttgaa aagaaaccag
     2041 aatatcaaga cgtcttacgt cagtcataag aataacagct gaaagttttg aactttcagc
     2101 tgttattcca tttatataga gttgtcacgg acttttatct atgataaagt taaagagacg
     2161 atatcttttg ggaaggaggc tgcgatatgt ataatttaat tttgggaatc gtgatcgttt
     2221 tatcgattgt tatggtcatt gcgattatga tgcagccaag caagcaaaat agtgcagcga
     2281 gtgcatttac cggcggtgcg gatcaactat tcggcaaaca aaaagctcgc ggctttgaag
     2341 ctgtcatgca gcgatcaact gcagttatgg gagctatctg gatgatctta ttatttgtcc
     2401 tagcatattt atcttcgaag tagttgaata agcctctcgc aaaacggcgg gcggcttttt
     2461 ttattgcaaa gagaacgctt aagaagaagt tatgaaagaa actatggtaa aatgaggcga
     2521 aagaggtgag acgagtgaga caattaccaa aaccccttta tgcaaaacat ggaaagcgag
     2581 cggttttgct gcttcacgct tactcaggaa gtccaaacga tgttcgaatg ctcgcacgat
     2641 ttttggaaaa agcagattat acagtttatg cgccgctttt taaaggacac ggaacaatgg
     2701 agccatatga tatcttgcaa gaaaaagcag aaagctggtg ggcagacact aaaaaagcca
     2761 tccatttttt acagtctgag cagttttctg atattgccgt attaggatta tcaatgggcg
     2821 gcatctttgc tgtacgagca ctagaagaag aatcagtgat tggcggcggt tttttctgtt
     2881 cgcctttgtc tcctgtaaaa acaaacgtgc ctgaaaactt tgaaaaatac gtacgtcaag
     2941 tgctgaagac agcaggtaaa tcagagaaag aaatcaatga aaaagcagtt gcttaccgct
     3001 cgttagctga acaacaatta atggatatac aagatcaggc agcaatcgta gaaagtaggt
     3061 tgtcagatat ccaacagccg atatttttag ctcaagctgg gaaagatgaa atgatcgacc
     3121 ctaatggcgt atttgaaact gcacgcaagt tgagccgtca gcgagtgaca cttcaatggt
     3181 atcctgaaag tggtcatgtg attacagttg gtacagcaag acgcgaatta gaaaaagacg
     3241 tcttggaatt tttagaaaaa ttaccttgga atgaggaata aatatgacaa aagaaacgat
     3301 aaaagagaaa attctctttt tcatggaaag cagtcgcaaa cgcagttttt ctatggaaga
     3361 aatcgctgaa ggtttagggt tccaaaaaag cgatgatttt aaattactag tacaaacgat
     3421 tgctcaaatg gaaagagaac agagtatagt tttcaataaa aaaggaaaag tgaaacttcc
     3481 tttaaaacca atcctgatcg aaggaacatt tcgagcaaat gaacgaggat ttggatttgt
     3541 aacgattgat cccgaagaag atgacatcta tatcccaaaa gaagcgactg gttttgcaat
     3601 ggatggagac accgtagcaa tcgatatcat gaagcgagca aatacagata tggatcgcgg
     3661 agcagagggg aaagtagtcg agattcgaga ccgggcgact actcagttag caggggaatt
     3721 cgttgcttat tcagaagaag aaatacaaga aacagatctt tacggcgttg ttatcccgaa
     3781 agatagaaag ctcaaccaat ttaaagtata tgcagcagca gagggagttc gtccagttga
     3841 cggaagtatt gtgctgatcg aactgaccca ttaccctgaa aaagggtatg cgactagttt
     3901 agaagggata atcaagcaag tgattggtca taagaatgac cctggcatgg atatcctctc
     3961 aattgtcgtg gctaatggta tccctacgaa atttcctgat gatgtattgt ctgaagcaga
     4021 tgaagttcca gatcaaatca gcgaaaagga tataactgga cgtagagatt taagaaatca
     4081 gctcattgtt acgattgatg gagaagatgc aaaagatcta gatgatgcag ttacggttaa
     4141 aaaattagat aacggtaatt attttcttgg agtacacatt gcagatgttt cttactatgt
     4201 gacacaaggc agtcaattgg acagagaagc atatgaaaga gggacaagtg tatatttgac
     4261 tgatcgagta attccgatga tcccgcaacg tttatcgaat ggtatctgtt cactgaatcc
     4321 ccatgttcca aggctgacca tgagttgcga aatggagatt gatccaaatg gacaagtagt
     4381 ctctcatgat attttcccaa gtgtgatcca aacaacagaa cggatgacct acacagctgt
     4441 caatcaaatc ttagaagatc aagacgaaga aacgatgcaa cgctatgctc agctcgtacc
     4501 tatgttccaa gaaatgggtg aattgcaccg aatccttgaa acgatgcgaa tcaaacgtgg
     4561 cgcgatttct tttgaggatc gcgaagcgaa aatccttgtt gatgctgaag gacacccaaa
     4621 tgacatccag ctaagaagca gaggaattgg tgaacgcttg atcgaatctt tcatgcttgc
     4681 ggccaatgaa acggtagctg aacattataa taaattaaat ctgccgttta tttaccgaat
     4741 ccatgaacag ccaaaagaag aaaaaatgca gcgcttcttt gattttgctt cagctttggg
     4801 cattctggtc cgaggaacga aaggaacgat cacaccaaaa gatttacagc atgtgatcga
     4861 aggagtagaa gacaaaccag aagctgcagt tatcaatact atgttgctaa gaagcatgca
     4921 acaagcacgc tattcagaag acaattttgg gcattatggc ttagcggcag attactacac
     4981 acactttaca tctcctattc gacgctatcc cgatctaatc gtccatcgtc tgatccgttc
     5041 ttacagtgaa gataaaagtg aaagcaatca aagttcgtgg gctgcggaac ttcctgaaat
     5101 tgcagatcat agttctaaga tggaacgtcg tgcagtagaa acagaacgtg aagtagattc
     5161 catgaagaaa gcagaattca tgatggacaa agtgggagaa gaattcgatg ggatcatcag
     5221 ctctgttgtg aaattcggcc tgtttatcga actgccgaat acagtagagg gattgatcca
     5281 tatcaatgaa ttgaaacagg actacttcca ttttgttgaa aatcatttag ctcttgtagg
     5341 tgaaagaact ggtctgactt ttaaaatcgg acagaaagtg cgagtaaaag tagtcaaagc
     5401 tgatccagat gaacgagcag tagattttga acttgtttcc gcagaagagg ttacagcgtt
     5461 ggaacggcca aaaacacgaa atggaaaatc aggaaaacgc gaaggaaaac aagcaggaaa
     5521 acgcccagaa agaaatggca agaagaacaa acgatatagc gatagtaagc aaacgttcgg
     5581 taagaaaaaa gggaagaagc cattttacaa aggtgttaaa aagaagaaaa agaaaaaata
     5641 aaatgagttg gaggaaacag ctatgccaaa aggcgaggga aaattaattg cacaaaacaa
     5701 gaaagctcgc catgattatt cgatcatcga cacgatggaa gcagggatgg tcttgcaagg
     5761 aaccgagatc aagtcgatac gaaacagccg gatcaatcta aaagatggat ttattcgcgt
     5821 ccgcaacgga gaagctttct tgcataatgt tcatatcagt ccttatgaac aaggaaatat
     5881 ttttaatcat gatccgttgc gcacgagaaa gttattatta cacaaaaaac aaatcatccg
     5941 gcttgaaaat gaattgaaaa atactggaat cactgttgtt cctttaaaag tctatattcg
     6001 taacggctat gccaaggtat tgattggtct ggcgaaaggg aaaaaatctt atgataaacg
     6061 ggaagatttg aaacgaaaag atatcgatcg acaaattgat cgaacattaa aaaatttctc
     6121 tagataattt cattatcctt tttcgcatat tcggtgcttt tgcttttact taatgataaa
     6181 atttgttagc atttaatctg ataaaacatg attatcatag gttttttctt agatcaggag
     6241 caccgtgtat aaagaaaaat tcgcttcgtt tttgactgaa ataaaaaagt gtctaatttt
     6301 catgaaaatg ttttgaattt tctgtttcat ggtggtatga taccgtgtgg ttagaaaccg
     6361 attggaaaaa accagatacg cacatgaatt gattttatgt gaatttcggg gaaaagaggt
     6421 gaaatggatt ggatgaacgc tcgctaacgt tccacattgg accaatttgg tttgatggta
     6481 cagtttgtat aatggtgtta ctgacctgtt tgattgtttt cttcttagct tactttttta
     6541 caagaaatct taagttgaaa ccaacaggca aacaaaatgc gatagaatgg gtcattgatt
     6601 ttagtcgagg aatcgtaaca gataatctgc ctagaaaaga attgagcaat ttccatttgt
     6661 tggcatttac attgttttta tttgtttttg ttgcaaacaa catcggttta gtaacaaaaa
     6721 tcgttttacc taacgaaaca acactttgga aaagcccgac agcagacccg tttgttactt
     6781 taactttggc atttataatg atcttactta ctcacttatt cggggtgaaa aagttaggct
     6841 tcaaaggata tttcgtaaat tcgttcttga aaccctatag ttttatgttt ccgatgaaac
     6901 tgattgaaga atttacaaac ttattaacac ttgctttacg tctttatggg aatatttatg
     6961 cgggggaagt tttgctaacc ttgattgcaa aaatgatgac aagcttaggc tggttctcat
     7021 taccattagc aattccatta gagatggtct ggatcgcgtt ctccttgttt attgggagca
     7081 tccaagcatt tgtctttgtc actttgtcaa tggtttatat gagccataag attgaagtag
     7141 aagaataata ctcggttaaa aaacaaacta ctatttatct attttaggag gaaaacaatt
     7201 atgaattata tcgcagcagc aatcgcaatc atgggagcag caatcggagc cggttatggt
     7261 aacggtcaag ttatctctaa aacaatcgaa tcaatggctc gccaacctga aatgtctggt
     7321 caattccgta caacaatgtt tatcggggta gctctagttg aagctgttcc tatcttaggg
     7381 gtagttatcg ccttgattct agtttttgcc gtttaattga atcagtatta aggcagaaac
     7441 aacatcgttt gttactgctt ttttacatgg aaactagaaa tactccaaag aaaggaaggc
     7501 tcgcctatgc tgaatcaatt ggcaattgca gaagttggca atgcgatgtt aggtaatatc
     7561 atcgttgtca gcggctcatt tttgatacta ctggctctct tgaagcactt tgcttgggga
     7621 ccaatcagcg atattttgaa aaaacgtgaa gacaagatcg ccaatgattt agattctgca
     7681 gaacaatctc gcatcaactc agcgaaaatg gaacaagaac gcgaacaaca attgttagcc
     7741 tctcgttctg atgcagctga tatcatcaaa aatgcgaaag aaagtggaga attaagccgc
     7801 caaaatattt tgaaggatgc tcaagaagaa gcagctcgtc taaaaagcaa agcccaagct
     7861 gatatcactg tagaacgtga ttcagcgctg aactctgtaa aagacgacgt tgcagaactc
     7921 tctcttcaaa tcgcggaaaa aatcttgaac aaagaattat ctccagaaat gcatgaatca
     7981 ttaatcaatc aatacattga aggtctaggt tcttcaaatg aaactagata aatatacagt
     8041 aggaagacgt tacgggaaag ctttatttga actggcgatc gattcaaatc aagcagaaga
     8101 aatctatcaa gatctcgtaa gtttacgtca aatctatgaa caagtacctg gattagggaa
     8161 tatgttaagt gatgttcgtc tagaacctca tgaaaaacga gaaatcatgg acaagcttgt
     8221 cagcggttat gatgggatcg ttaaaaactt tttagaagtt gtttatgagt ataaccgaat
     8281 ggatgacctt ttgttcatga tcgaagaata tgaacgtcga tatgatgaac atcaagggtt
     8341 actattggga agtgtcacaa cagcagtccc actttcagac gaacaacgaa tacaattaga
     8401 aaagaatgtt gcaaaaacaa tggactatca atcagttgaa ttaaaacaaa tcgttgattc
     8461 ttctattatt ggtggcgcga ttgttgaagc caaccatcga gtaatcgacg gaagcattcg
     8521 cacgcaatta gaaaaaatgc gtaatcaatt aaacagatag tacaaagagg taggtgaatc
     8581 gaatggccat caaagcagaa gaaattagtg ccttgattaa agaacaaatt gaaaattatc
     8641 aaaacgtgct ttcagtcgaa gaaatcggta ccgtaactta tgtaggtgac gggatcgctc
     8701 gtgcacatgg tttagaaaac gcgatgagtg gtgagttgct tgaattttca aacggctcat
     8761 acggaatggc gcaaaactta gagtcaaatg atgtaggtat cattatcctt ggcgatttcg
     8821 agtccattcg tgaaggagat aaagtaaaac gaacaggtaa gatcatggaa gttccagttg
     8881 gagaggcctt gatcggtcgg gtagtcaatc cgctaggtca accaatcgac ggactaggtg
     8941 aaatcgttac tgacaaagct cgtccagtag aagcgatggc accaggtgtt atgcaacgta
     9001 aatctgttaa cgaaccaatg caaacagggc taaaagcgat cgacgccctt gtgccaatcg
     9061 gacgcggaca acgtgaatta gtcatcggtg accgtaaaac agggaaaact tctattgcga
     9121 tcgatacgat catcaaccaa aaaggtcaag atatgatctg tatctatgta gcaatcggac
     9181 aaaaagattc tacagttcgt acacaagttg aaacattgaa aaaatatggc gcaatggatt
     9241 acacaatcgt tgtgaatgcc ggtgcgtctc aaccagcacc attgctttat atcgcaccat
     9301 atgctggtac tgcaatgggt gaagaattca tgtacaacgg taaacatgta ttgatcattt
     9361 ttgatgatct ttcaaaacaa gctgttgctt atcgtgaact ttccttgcta cttcgccgtc
     9421 caccaggtcg tgaagcttat cctggggatg ttttctactt gcactcacgt ttattagaac
     9481 gtgcagcaaa attaagtgat gatttaggtg gcggttcaat gactgcctta ccatttgttg
     9541 aaacacaagc tggagatatc tctgcttata tcccaacaaa cgttatttcg atcactgatg
     9601 gacaaatctt cttagaaagc gacttgttct acgcaggtac tcgtccagcg gttgatgccg
     9661 gactatctgt atctcgtgta ggaggttctg cgcaaatcaa agcaatgaaa aaagttgctg
     9721 ggactttacg cctagactta gcaagttacc gtgaattaga agcatttaca caattcggtt
     9781 ctgacttgga tgcagcaaca caagcaaaac taaatcgtgg acgccgtaca gtagaaatct
     9841 tgaaacaaaa attgcatgca ccgctagctg ttgaaaaaca agtagtgatt ttgtatgctt
     9901 tgacacatgg attcttagat agtatccctg tagacagtat tttagacttc gaacatgaat
     9961 tattcgaata tctggatacc aatcattcag atatctttga aacaatccgt acaacaaaag
    10021 atcttccaga agaagaagcg ttgaacagtg cgattcagga atataaagac atgttcttag
    10081 ctacaaaagg aagtaattcc tctacagaag ataaattgaa atccattcaa aatgcatagt
    10141 gaggtgagat gaatgggtgc ttcattaaat gaaatcaaga cacgtatcgc ttcaacgaaa
    10201 aaaacgagcc aaatcacgcg ggcaatgcag atggtgtctg cttctaagtt gacaaaatct
    10261 gaagcttctt cacagaagtt tcaggtttat gcaacaaaag taagagaaat cgttacgcat
    10321 ttgactgcta ctcagttaaa tgatattgcc tcagaaaatc ctagagggga tatcaattac
    10381 aacagcatgc tgctcagccg tcctgtgaag aaaactggtt atatcgtcat cactgcagat
    10441 ggcggtttag tcggtggata taacagctcg atattgaaac aaacgatgtc tattttagaa
    10501 gaagaccacc aatcacccga tgattacgtg atgatcgcaa ttggcggaac tggtgcagac
    10561 ttctttaaag cacgcggtat caatctagca tatgagctgc gcaatctatc tgatcagcca
    10621 agctttgatg aagtccgcaa aattgtaaat atggcaacaa ctatgttcca aaacgaagta
    10681 ttcgatgaat tatacgtatg ttataaccat catatcaatt cgctaactag tcagtttcgt
    10741 gtagaaaaaa tgctgccaat ctcagactta gatccagaag aagcaacgac tttcgaacaa
    10801 gaatatattt ttgaaccttc aaaagaagaa atcttgtctc agttattgcc tcagtatgct
    10861 gaaagtttga tctacggtgc gatcgttgac gccaaaacag cagaacatgc tgctggtatg
    10921 acagcaatga aaacagcaac tgataatgct gctaatatca ttgatgagct gacggtttct
    10981 tataaccgtg caagacaagg ggctattacc caagaaatta ccgaaattgt tgccggagct
    11041 tcggcactag aatagtattg agattggagg aaaaaagatg agttcaggca agattgttca
    11101 agtaatcggt cccgttgtcg acgtggaatt ttctttagac caatccttac cagatatcaa
    11161 caacgcatta gttgtttata aaaatgacga aaataaatca aaagttgttc ttgaagcagc
    11221 gttagaatta ggggacggag tgatccggac cattgcgatg gaatcaacag atggtttaca
    11281 aagaggaatg gaagtcattg atacaggcaa agcaatctct gttcctgtag gtaaagaaac
    11341 attaggtcgc gtattcaacg tactaggaga tacgatcgat ttagaaacac ctttcccaga
    11401 agatgcggaa agaagcgaaa ttcataaaaa agcaccagcc tttgacgaat taagtacaag
    11461 tacagaaatt ttggaaacag ggatcaaagt tatcgatttg cttgccccat atttaaaagg
    11521 tgggaaagtc ggactattcg gtggtgccgg tgttggtaaa accgtactga tccaagaact
    11581 gatccataat atcgcccaag aacatggtgg tatttctgta tttaccggtg taggtgaacg
    11641 tactcgtgaa ggtaatgact tgtattatga aatgaaagat tcaggagtta tcgaaaaaac
    11701 agccatggtg ttcggacaaa tgaacgaacc accaggtgca cgtatgcgtg ttgctttgac
    11761 tggtttgacg attgcggaat atttccgtga tgtagaaggt caagatgtac tgttgtttat
    11821 cgacaacatt ttccgtttca ctcaagctgg atctgaagta tcagccttgt taggacggat
    11881 gccttctgcg gttggttatc aaccaacatt ggcaacagaa atgggtcaat tgcaagaacg
    11941 tatcacatct acgaaaaaag gttcgatcac atcgatccaa gcaatctatg tgccagccga
    12001 tgactacact gacccggcgc cggcaacagc attcgcccat ttggatgcga caaccaactt
    12061 ggaacgtaaa ttaacagaac aagggattta tccagcggta gatccattgg cttcttcttc
    12121 aagtgcttta gcacctgaaa tcgtgggaga agaacattat aaagtagcaa cagaagtcca
    12181 acacgtattg caacgatatc gtgaattaca agatatcatt gctatcttag gtatggatga
    12241 attatccgat caagaaaaag tgttagtttc tcgtgcccgc agagtccaat tcttcttgtc
    12301 acaaaacttt aacgtggctg aacaatttac tggtcttcca ggttcatatg tccctgtaga
    12361 agaaacagtg aaaggattcc gcgaaatctt ggaaggcaaa tacgatgatc ttcctgaaga
    12421 agctttccga agtgttggcc gaatcgaaga cgtcgtagaa aaagcgaaaa cactaggcta
    12481 ctagaaaggg gtgccccatg gatcaatatt taacagtaaa tgtggtaact cctgccggtt
    12541 tggtctatga tcaccatgca gctatcgtcg ttgcacgtac gacagctggt gagcttggga
    12601 ttttgcctaa acatgcacca atcatcgttc cattgacgat tgatgaagtt cgtgtaaaac
    12661 gaacagattc agatacccac gtcgattgga tcgctgttaa tggcggaatc atggaagttc
    12721 gtgataatgt tgtttcaatc gttgctgata gtgcggaacg tgaacgtgat atcgatgtat
    12781 ctcgtgcgga acgtgcaaaa caacgcgcag aacgccaaat cgaagaagca aaagcaaaac
    12841 aagatacgaa cgaattgaaa cgggcaactg ttgcgttgca ccgagcaatc aatcgtatca
    12901 aagtatctaa gcactcataa aatgagatgc ggatgtttat ccgtgtttaa gaacagtaaa
    12961 aagaggttat gacagaagtg gtcagcttca agacataaga aggaatttac gaaaattgct
    13021 tctcaaattt ttgtgaaatc tcagcttatt tttcgaagaa gctacttctg gaacaccgta
    13081 tatcagaggt tgtgaaatca gcgttttgtc ctgagtatta gagaaacaaa tggaaaatag
    13141 ttcctcatat tttgccgttt tttgagctaa taccgagggt cagatgattg aacaccgttt
    13201 atttggaata agggactgcg acaagacttt tgtctcagtc cctttttttg catattttta
    13261 gcatttattt cctaaaaaat gtaaggggat tcctatattt ttaagtatac ttgtttttcc
    13321 ttttatacat tttatggtat tatcatttta ttagttatta taaaacaatc gttagaaagg
    13381 acgtcattat gcaagtatac ggaattgatg cggtgcttcg aatcgtgagt catttggcgt
    13441 ttatctactt agccttctgg tctttacgtt cgttacgcat tgaaactttt ttcagaccaa
    13501 tgcataatac gcaaattaga atggcaatcg tacttttttc aattttttta gggtacactg
    13561 caagtaattt tttcttagag gttatcgctt tatgccgaaa tcttttcgtt agcctgtaaa
    13621 ttttaaaaaa aggtactatt ttaaaagcaa ggatgttata atagaaaaga ttttgagtaa
    13681 gtgtatgctc attggaattt tttggaggga acaacatgga agagatcatc gtaagaggtg
    13741 gcaatcaatt aaatggaaca gtaagaattg aaggagctaa aaatgctgtt ttgcctattt
    13801 tagctgctag tttgttagca gaagaaggta ttacgacatt agacaacgtt ccgattcttt
    13861 ctgatgtctt cactatgaat caagtgattc gtcacttaaa cgtagatgta gattttgatg
    13921 aacaaaagaa tcaagtaaca atcgacgctt caagacaatt agaaatcgaa gcgccttatg
    13981 agtatgttag tcaaatgcgt gcttcaatcg ttgtgatggg tccgctactt gccagaaatg
    14041 gacatgcaaa agtagctatg cctggtggat gtgcgattgg taaacgacca atcgatttgc
    14101 atttaaaagg atttcaagct ttaggagcaa aaattattca aaaaaacggc tatatcgaag
    14161 caattgcgga tgaattgatc ggtaacacga tttatttaga tttccctagt gtaggtgcta
    14221 ctcaaaatat catgatggct gccgtaaaag caaaaggaac aaccatcatt gaaaacgtag
    14281 ctcgcgaacc agaaatcgtt gatttagcaa acattttgaa taaaatgggc gctcaagtct
    14341 atggagctgg tactgaaaca atgcgtattg aaggcgtgga tcatttacat gcagtcaacc
    14401 actcaatcgt acaagatcgt atcgaagcag gtacctttat ggttgctgct gcaatgacac
    14461 aaggcaatgt gctgattgca gatgctatct ctgaacataa ccgcccattg atttctaaat
    14521 tgatcgaaat gggtgcagaa atcattgaag aagaaggcgg agtccgtgtc atcggaccaa
    14581 aacatatctt acctacagat gtaaaaacga tgcctcatcc tggtttccct acagatatgc
    14641 aagctcaaat gacagctatc caattagttg cagaaggtac aagtgtggtg actgaaacag
    14701 tgtttgaaaa tcgtttccaa catttagaag agatgcgccg tatgaacgct catgtcaaaa
    14761 tcgacggaaa tgtagcaatc atggatggaa accatgaatt gcaaggtgca gaagtatatg
    14821 caacagactt gcgggcagca gcagcattag ttttagctgg cttgaaagca aatggaatca
    14881 cacgtgtgcg taacttgaat tatctagacc gtggatatta taatttccat atcaaactac
    14941 agcaattagg tgcagacgtc gaacgtgtag acatggatca aacttctgct gaaaaaacag
    15001 cacaaacgat tgcttaagga agtggctgaa tgagtaacca acgatatatc ttattaactt
    15061 tgataaagat tttagtggtg atcttattgc ttatccttct ttttgtggcc ggaacgatga
    15121 tcggatatgg tgtcatcggt ggcggcaatc catttaaagt attccagcca agtttgtgga
    15181 ttcatattcg agactttttt cattgataaa taagaatcac agtggttcta gtcgatatga
    15241 agtgagccat gaagcagaac atgataaaag aaaacagaag ggaacgttga cgttagtcgc
    15301 gatccctttt tttagtaaaa gaaaagaagg aatctaattg atgaagaaga tattgattta
    15361 tttagttaga ggatatcagc gctttatttc gcctgcattt ccacctagct gccgttatta
    15421 cccaacctgt tccaattata tgataaaagc aattcaaacc catggtgcgc taaaagggac
    15481 ggtaatgggg actgcacgga tcttacgctg tcatcctttt gtcaaaggcg gtatcgatta
    15541 tgtaccattg acattccgat taacgcgaaa taagaaagat aaaaaagaac cagattataa
    15601 aaaggttgtg aaaaatacgg gtagcactga gcgataaaga aaaagaggaa atttattgtc
    15661 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
    15721 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
    15781 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
    15841 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
    15901 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacagct
    15961 agcttcaaac caaactcgga tcattatacg tactggcact actagtagcg ctgcgttaca
    16021 cctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
    16081 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
    16141 tcacttacct aaaaatagct ttaactaata aactttcaat tcgagaaaat gctttcaaat
    16201 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
    16261 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
    16321 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaaa cgcaattatt
    16381 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
    16441 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
    16501 tggatttaat attttccgag atttggaaac tctgtttcaa ctcccagtaa cgattgaaaa
    16561 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgtg attatcaaga
    16621 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
    16681 aaataaaggg gcacatcttt acggtggaga atttgggttg atgttcttag atggcgataa
    16741 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
    16801 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
    16861 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
    16921 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
    16981 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
    17041 tttcgaaccg cagattttat tatgtgagta cagaaacgat gctaatctta taggtgcagc
    17101 agcaaactat ctcgctgtac gtcaaggaga gaattaagag ctttagagaa ggtgcagctt
    17161 gcataaaaga agagaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
    17221 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
    17281 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
    17341 tttataggga aaaaaatgat tggtgagatc ttagcctatg ggccaaaaga atatgaaatt
    17401 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
    17461 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
    17521 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
    17581 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
    17641 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
    17701 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
    17761 ttcgagagct cttttttttt gctttgctac cttgttcctt gaagattctg ctgaattaag
    17821 atagagttaa gttaactaca agaattggag ggatccacat gaaatggaaa gaaaaagtag
    17881 acgaagcagc tgaaaagtta tatgatttgg tcaaatcaga aaaatacaat attgaagtga
    17941 atattccgaa aaaaggcgga aaagcggtcc aggtaaaatc aaaacgccca acgaatcata
    18001 caaaaaaatg gatggctaaa aaccgctaat aataacaaaa gatccataag tcggcatttt
    18061 catcgatttt agggtctttt gttattttct aggttgaaca tatctaaaaa attgtttctg
    18121 acaataggag tagggagaac gatgtgtgtc taaatcctct gttgatggat agaaaccttt
    18181 atctttttca gttgtgaatc aggtatatac cagttataat agaagaaacg aaaggacggg
    18241 tgtacgttat gtcgaatcaa ttacctgtat atatacagat tcatgaccaa ttaaaaaatg
    18301 aaatcgaaca aggtatatgg aaagtcggag accgtcttcc ttcagaaaga gaattagcag
    18361 tgaaattcaa tgtcagccgt atgacgttga gacaagcaat tcaaaacttg gcagatgaag
    18421 gaatcttaga aagaaagatc ggttcgggta cgtatgttgc gcgagaaaaa gtacaagaaa
    18481 aaatgtctgg tgcaacaagt tttacagaaa ttatggaatc acaaaatcga gtaccgtcta
    18541 gtcggacaat ctcttatttc ttgacttcgc caagctcaag tgaaatggaa aaactaaact
    18601 tgagtaaaga tgacacgatc ttgcgaatgg aacgtattcg tttcgcagat gatgtcccta
    18661 tttgttttga agttgccagt gttccacaaa agctgatcga tggctacagc aaagcagaga
    18721 ttactgaatc gttgtatcgc acgctagaag aaaaaggcgg gaaaaagatc ggtccagcga
    18781 atcaaacgat tactgctgtg ttggcttctg agaaaattgc tgactattta gaggtaaaac
    18841 gaagagatgc agttcttcgt ttgcgccaga tttcttattt tgaagacggt acgccgtttg
    18901 agtatgtgcg tacgcaatac gtaggaaatc gttttgagtt ttatttggaa aaataaaaaa
    18961 caggtgatcc ctgattcctt attagaaata aaagagaatc agaatcacct gtttttatat
    19021 atgatcagtt atcagttgct cgtgataaga aacagaaccc tcttcaaatt ggacttgtcc
    19081 gttcagcagc tcaatgatgg attctttaaa gtggttagca cttttttcat ctacagcaca
    19141 gatgacgcta acttgatcag tatattggat ttcttttata aaaaaatgtt ggagttcaag
    19201 ataattctgt aattttccta gttgcggata cgtgatcatc acagagatct cctgttgcaa
    19261 ggtaccttct acgattccaa tgtcagacaa tgcttgagag accgcatgag tgtatgctcg
    19321 tattaatccg cctgtgccga gtttcgttcc tccaaaatat cgagtgacta ctgcagctac
    19381 attgatcagt tgattttttt tgaggacttc caacatcggt acgcccgccg ttccacttgg
    19441 ttctccatca tcgctgcttc gctggatttc atttttttct ccaatgatga aggcgctgca
    19501 gttatggttc gctttccaat gttctttttt tatttcttga atgaaatttt ttgcttggtc
    19561 ctctgattct attcgtctaa gagaacagat aaagcgtgat tttttgatct caatctcact
    19621 ttgtccattt tcttttattg tacgatagcg ctcgatcatc ttgtcacctc tttttttcat
    19681 tttctttatt cagtataaat aaagttctag gttgtttcaa cactgtaacg gttgcgcaat
    19741 tgctgtagta tgcgataata aagacaaagg caggtggatc tggggatgca ggaacgaatg
    19801 aaaaagtacg atgcaattac gcattatttg aagaacaatg gcggctctca agtaacgttg
    19861 acctttaccc aatttgacga actgctgttt cccagtaacg gacttcccaa aacagcaagg
    19921 gaaagtacag attggtgggc aaatgattat aaacaccctg aaaaaggtgc ctatggctgg
    19981 ataaatgcag gctatgaagt agttgtcatc aatttggaca aagaatatgt cgtgttcaat
    20041 aaattagtga aatctagttg gctatttgat taaataaacc gcgtttagaa aacgttgaca
    20101 aatttctttc tttttatata ataaagtaac agacgcgaag aaaacgtttg cgtagtttgt
    20161 tttaaaaagg agagaaaaat atggctaaaa aaacaatcat gcttgtatgt tcggctggta
    20221 tgagcacaag tttactagta acaaaaatgc aaaaagctgc tgaagcaaaa ggaatcgact
    20281 ctgatatttt cgctgtgtcc gcttctgacg cagataacaa tcttgcaaat aaagacgtgg
    20341 atgtgttgtt attaggccca caagttcgct ttatgaaagc tgattttgag aaacgtctgg
    20401 aaccaaaagg cattccttta gatgtcatca atatggctga ttatggtatg atgaatggcg
    20461 aaaaagtgtt agatcaagca atcgcgctca taggtgaata aatagaacag tataactatc
    20521 gaacaagcga tccaaaaaat agatcgcttg ttttttcgta tattttttta gggcgaataa
    20581 tatgaatcat ttttggggta gaaggcttct gacgagagat attaaagcaa tagactgtga
    20641 ggaggtaaat ttaccaaatt atgagaagat cgcagcagtg gaacgtttgg gcaactggat
    20701 tctttgtcat cgctgtggaa tgaggacgtc cgtcattgtt ggacagcttg cagattacgg
    20761 ttatttttgt acacattgtc tatatttagg gtgatgcgac actcaacaag atttatattt
    20821 gtttgatcag cctgaagcaa aacctcgaga agtcgtcttt ttttggacag gacagcttac
    20881 tgaaaaacaa acggaaatcg caaagagaat actttgccat tcagaaaaaa gacatcatct
    20941 tatttgggct gtaacaggtg cagggaaaac agagatgctt tatcctattt tagtggaaac
    21001 tttaaaagct ggaggaagag tagcgatttg tacaccgcga gtcgatgttt gtaatgaatt
    21061 gtttttacgc tatcgttatg tttttccaga agaaaaaatc acgttgctcc atgggaatac
    21121 agcaacggct tataccttta cttcttttgt tatctgtacg attcatcagc tataccgttt
    21181 ttatcggtcc tttgatttaa tagtgatcga tgagatcgat gcgtttcctt ataacgggga
    21241 tgctgggcta gctcacgctg tgcaaacagc aatcagatca aacggccgat tcatctactt
    21301 aagtgccacg cctgatgaga agttactaaa ggaaatcaag cagacatttg agctccacaa
    21361 acttgccttg cgctttcatc ggcgcttgct tcctgaaccc gtgcttgttt tcatgaataa
    21421 ttggcgacaa aaatgtggaa acaaaaagaa aatcaactct ttggtgcgga tcattcagca
    21481 actaatcaaa gaaaaccgta tccttttatt ttgtccaagt attacgatga tgcatcgttt
    21541 aaaaatcaca ctgcaagaag cttttccaga atatgagata acagatgttt cttcacaaga
    21601 cgatcaacgg gcaaagaaag ttcagaaaat gcgagaagca atatacgaga tactgttaac
    21661 cacaatgatc ctagaaagag gagtcacatt tgaaagaatc tctgtcatcg ttttaggagc
    21721 agatcatcca gtttttacta aatcctcttt ggtgcaaatc gcaggaagag ctgatcgtaa
    21781 aggtccttat acgaacagtc gagtctattt tttctatgaa gaaaaaactt cagctattcg
    21841 aaaagcctgt caggaaatca aagaaatgaa cgaagaaggg aagcagatgc tgtgagatgt
    21901 agttgctgcg gtaaagacat cattcaaaat ttaacattca gcgagatcat cggagtgtcg
    21961 aaatctagac ttcctcagac atgttcagtt tgccgcgcac aattccattt attagaagca
    22021 aaaggttgtg caggttgtca aaaaccaatc catttgaaat acgaggagac gaaaaagaaa
    22081 gcaaatacta gtttcgttta ctgcaacgac tgtcaagaat ggaagaagaa atatcctgca
    22141 tatgattttc aacaccgcgc cttttttacg tacgatgaaa agatgcaggc ttggatcaat
    22201 cggtacaagt ttatgggaga tatccgatta gcagggactt ttgcatataa atggactcag
    22261 ataaaaaaag attacccggc atatatttat tgtccaatac ctttatctga aaaaaggtgg
    22321 ctagaaagag gattcaatca agtaagcgag atgttgaaag cagcaaaaat tccttttcag
    22381 atgctgctca aaagagagca acatctgctt gctcaagcaa aaaacacgcg aaaggaaaga
    22441 ttggagatgc ctcagccttt tgagcttgcc gtacctcttt ctaagataca acataaaaaa
    22501 atattgatta ttgacgatgt ctatacaaca ggacagacgc tttttcatgc agcagattgc
    22561 ttgcagaacg cacagccgaa aatcatccga accatttctt tggcaagatg aatcagatgt
    22621 ggaaatttga tagcgattta atttgcaaat aacctagagt tcgatataat agaattaaga
    22681 agagggaaag agtggtcctt ctccttcttg attgtggtag acgaaagggg taatttttat
    22741 gtttagatat aatgtacgcg gcgaaaatat cgaagtaact gaagcgattc gcgactacgt
    22801 tgagaaaaaa gtaggcaaac tagaacgcta tttcagtgac gcacccgatg caacggcgca
    22861 tgtgaactta aaagtttata cagaaaaaac agcaaaagtg gaagtaacga tcccattacc
    22921 ttatcttgta ttacgtgccg aagaaacttc tccagattta tacgcaagta tcgatttggt
    22981 tgttgacaaa ttggaacgcc aaatccgcaa attcaaaaca aaaattaatc gtaaatcccg
    23041 tgaaacgggc atgaatactg cagatgctgc tgctttattc aatgaagagg acgaaaacga
    23101 aaatgattct gaattagata tcgtacgtac gaaacgcctt tcattgaaac caatggatag
    23161 tgaagaagca gtcttacaaa tgaacatgct gggacataac ttctttattt ttgaagatgc
    23221 agaaacaaat ggtacaagta tcgtttaccg ccgtaaagat ggaaaatacg gactgattga
    23281 aacagactga tcagccttac ttaaataaca acgaaaactt gcagcagcta ctgacagctg
    23341 ccgcaagttt ttttgagttt cctcctcttt tagatgaaat atgaataaat tatgaagttc
    23401 ttactttaat acgcttaaga tatttcaatt atctataact aatgataaaa tgaaaagtaa
    23461 agtctacata gtctggataa tacacagaag gaaaaggaga ttacacaacg catggccaat
    23521 ttgattcgtt cacttatcga aaacgataag aaagaactaa aacgtttaga tagcattgca
    23581 aaaaaagttg aagcatacgc tgaccaaatg gcagcattaa ctgatgaaca attacaggca
    23641 aaaactgctg aattcaaggg cagataccaa aaaggagaaa cattagatca attacttccg
    23701 gaagcttttg cagtcgtccg agaagcagca aaacgtgtat taggtttata tccataccac
    23761 gtacaattga tgggtggaat cgtgcttcac gatggaaata tccctgaaat gcgtactggt
    23821 gaaggtaaaa ccttgaccgc aacgatgcca gtatatctaa atgctctgac tggcgaaggg
    23881 gtacacgtag ttaccgtcaa tgaatattta gcaacccgtg actcgacgga aatgggcgaa
    23941 ctttataatt tcttaggatt aacagtgggg ttgaatatca actcaaaatc ttcggatgaa
    24001 aaacgcgagg cttataattg tgatatcact tatagtacga ataatgaatt aggatttgac
    24061 tacttgagag acaatatggt cgtttaccgc catcaaatgg tacaacgtcc gctgaattat
    24121 gccattgtcg atgaagttga ctcaatcttg attgatgaag cgagaacgcc gctgatcatt
    24181 tcagggcaag cagaaaaatc cacagcttta tatacaagag cagacaactt cgtgaaacgt
    24241 ttgaaagaag aagaagatta taaaatcgat gtacaatcaa aaacaatcag tttaaccgaa
    24301 gcagggatcg aaaaagcaga agaaacattc ggtttggata acttatacga cattgaaaat
    24361 actgcattga cccatcactt ggatcaagca ttgagagcca actatatcat gcttttagat
    24421 atcgattatg ttgtccaaga cggaaaagta ctgattgttg accagttcac tggtcggatc
    24481 atggatggac gccgttattc agatggactt caccaagcaa tcgaagctaa agaaggcgta
    24541 gagatcgaag acgaaacgaa aaccatggcg acgatcactt tccagaacta tttccgtatg
    24601 tacaagaaac ttgcgggaat gactggtaca gctaaaacag aagaagaaga attcagagaa
    24661 atttataaca tccaagtata ccagattccg acaaatcgtc cggttatccg tgatgatcgt
    24721 ccagatttgc tttacccaac attacaaagc aagttccacg ctgtcgtgca agatatcaaa
    24781 gatcgctacc gcaaaggtca acctgtgtta gtcggaactg ttgcggttga aacatctgag
    24841 ttattatcag atatgctgaa tcaagaacgt attcctcatg aagtgctgaa tgcgaaaaat
    24901 cactttaaag aagcagagat catcatgaat gctggtcaaa aaggtgctgt gacgattgct
    24961 accaacatgg ctggtcgggg aacagatatc aagttaggac ttggggtaag agaacttggt
    25021 ggtctagcag ttatcgggac agaacgacat gaatctcgtc gtatcgataa ccagcttcga
    25081 ggacgtgcag gacgtcaagg agaccctggt atgtcacagt tctacttgtc attggaagat
    25141 gatttgatga aacgattcgg ttcagaacga atcaaagctt tcttagatcg gatgaagatc
    25201 ggtgaggaag atgctgttat ccaaagcaag atgctgacga aacaagtaga atctgcacaa
    25261 aaacgtgtag aaggaaataa ctatgacaca cgtaaaaacg tcttacaata cgatgatgtg
    25321 atgcgtgaac aacgtgaagt aatctataaa cagcgacaag aagtaatcat ggaagaaaaa
    25381 agcttatcca agccactaat gaacatggtc aaacggacaa tcagtcgtgt agtagatgcg
    25441 catacacaat tagagaaaga aaattggaat ttggaaagta tcatcgattt tgccggcagt
    25501 actcttgtcc atgaagatag cattactctt gcagatatcg aaggaaaaac agctcaggag
    25561 atcaaagagt atctaaacga acgagcacaa gaagtattta ataccaaagc ggctcaacta
    25621 aatggtccag agcaactgtt ggaatttgaa aaagtcgtga tcttgcgtgt tgtggactct
    25681 aaatggacag accatattga tgcaatggat caattacgtc agtcaatcgg cttacgtgct
    25741 tatggacaga acaatccatt agtcgaatat caaacagaag gctataagat gtttgaagat
    25801 atggtaggcg ccatcgagta tgaagtcact cgaatcttta tgaaagctga gatccgtcaa
    25861 aacgtacagc gtgaacaggt ttctcaagga acagcttctc actcagaaga cggagatgcc
    25921 aaagaaaata gtaatactag cgcgaaaaaa cagccaatcc atgtgaataa ggtcggaaga
    25981 aatgatcctt gtccttgtgg aagcgggaaa aaatataaga actgtcatgg aaaaaatgca
    26041 aactaatttc tgacagcagg attggtgaga caaattcttt ttttaagaat tcgtctcacc
    26101 ttctttctgt tatttgctga ttctgttaga ctagatataa tgaaaaaagt atagtgaaag
    26161 aaggaaaaaa catggaaata tccgaaattc gaaatctcct gacagaaatg caggaaaagg
    26221 tcacaagttt caggaggtct ctttgactta gatcagctgg aagaagacat cgcggaagca
    26281 gaagcaaaaa tggctgaacc tggtttttgg gatgacagcg aagccgcaca aaaagtgatc
    26341 agcgaaaata acgctaataa agaaacctat gaccaattcc attctcttgc cgaagaacta
    26401 gaagaaatcg aattgatggt ggagatgctg caagaagaac ctgatgcagc aatgcaagaa
    26461 gaagcagaaa cacgtatcaa tgcattagat gaaaaaatga agacgtatga attatctatg
    26521 ctgttagacg gaccttatga tcgaaacaat gcgatcgtcg aattgcatcc aggggctggc
    26581 ggaacggagt cccaagactg gggcagcatg cttttacgta tgtatacacg ttgggcagag
    26641 cagcatggct atcaagtaga aacactagat tatcaagcag gtgatgaagc agggatcaag
    26701 agtgtgaccc tgctgattaa aggacataac gcttttggtt atctaaaatc agaaaaaggt
    26761 gttcatcgcc ttgtacggat ttcgcctttt gactcagcga aacgacgtca tacttctttt
    26821 tgttcggtag atgtgatgcc agagcttgat gaaacgatcg atatagaaat caatccagat
    26881 gatttgaaaa tcgatacgta ccgagcaagt ggtgcaggtg gtcagcacat caataaaaca
    26941 gaatctgctg tacggatcac tcacttgcct acaggaacag tagtagctag tcaggcacaa
    27001 cgctcacaat tgaaaaaccg tgagcaagcg atggggatgt taaaagctaa gctttatcaa
    27061 ttagaagtgg aaaagaaaga acaagaagca gctgcacttc gaggagaaca aaaagaaatc
    27121 ggctggggtt cacagatccg ttcttatgtt ttccatccct attctatggt aaaagaccat
    27181 cggacaaacg tagagacagg aaatgtccaa gcagttatgg acggtgacct tgatttattt
    27241 attgacggct atttaaaaat gcatctacaa taagaaccca ttgttaaatt gaaataaaat
    27301 tgtaagattt tgcaagcatg ttgaaacatt gccatgctat aatagctaaa gactgaaaaa
    27361 gatatggaga gaacgccatg attgaaatga aggatgtaat gaagaagtac tcaaatggta
    27421 cgaccgctat ccgcaatctc tcgattgtca tcgaacaagg agagtttgtc tatgtggttg
    27481 gtccgtctgg agccggtaaa tctacattca tcaaattgat gtatcgagaa gaaaaagctt
    27541 caaaaggaac tttgaacgtc gcaggtcatg atctaatagc aatcaaaaac cgcgaagttc
    27601 cttatctacg cagagaaatc ggcgtggtgt tccaagacta taaattatta ccaagaaaaa
    27661 cagtatatga aaatgttgcg tacgctatgc aagttatcgg cagaaaacct cgagatatca
    27721 aaaaacgagt aatggaagtg ctggaccttg ttggtttgaa acacaaagtt cgagtctttc
    27781 ctagcgaatt atccggtggg gaacagcaac gtgtctctat tgctcgggca atcgtgaata
    27841 cgcctaaagt acttatcgcg gatgaaccga caggaaatct ggatccagaa aactcatggg
    27901 aaatcatgaa attattagat cggatcaatg cccaaggaac tactgtcgtg atggctacac
    27961 ataacagtac gatcgtaaat acgattcggc accgagtaat tgctatcgaa aacggccgca
    28021 ttattcgaga tcaagcggaa ggggaatatg gatacgatga ttagaacctt tttccgccat
    28081 ttattagaaa gtatcaagag tttgaaacgt aacggctgga tgacagttgc ttcagtcagt
    28141 gcggtaacga tcacgttgac tttagtcggt gtattcatgg cagttatcat gaatgcaact
    28201 aaattagctc aggatataga aggaaacgtt gatgtatctg tattcgtaga tatcggtaca
    28261 aaagacgaag agatgaaaaa gctagaaaaa gaattgaatg acttagatca tgttaaaaaa
    28321 gttgaatttt caagtaaaga acaggaattg aaaaaaatcc aaaacgaaat gggtgattcc
    28381 tggaaattgt ttgaaggtga caataacccg ttatatgatg tgtatgtagt aagtgctact
    28441 gatccttctt atacaaaaca agtagcagaa gaagcagcag atttgaagaa tgtttctcgt
    28501 tctgattacg gtggagcttc ctcagatcgg attttccaaa tcgctggtgc agttcggaca
    28561 tggggattag ttgcagcggc attgctgctg ttcgtagcga tgtttctcat ttcgaacacg
    28621 attcggatca cgattttgtc tagacagcgt gaaattcaaa tcatgcgttt agtcggtgca
    28681 aaaaatggat atattcgctg gccgtttttc cttgaaggtg gctggatcgg tctgatcggt
    28741 gcgattcttc cgattttgat catcacattt ggttatgcat ggtttttcca attgatcaat
    28801 ccatcattat tacgttccca ttattcattg attcatccac aaaatatcgt ttggaaaatc
    28861 aatcttttaa tggtcggcat tggtgtgatc attggttcac ttggctcgat catttctatg
    28921 agacgtttct tgaaattcta ataccacaat ataaataaaa tgagaaagtt ggacagtttc
    28981 gttccagctt tcttttttta ttggctagga gaatagaagg aagcggcttt tttcccttta
    29041 ctttaaaaaa caacttgggt attcttaagt tggtagagga agaggtgaag ccgtgaaaat
    29101 tatcgttgac aattttttta cgatcctttt gattatgaat attttgcttt cctttatcat
    29161 cgtttttcga gaaagaaagg aaactgctca aacatgggca tggctgctcg ttttgatgtt
    29221 cattccagtt gtaggattta ttttatatat ttttttagga agagggattt ccaaagagaa
    29281 aatctttgat ttgaagatcc aagggaaaat cggtaagaac ctggaaattg aagaagacaa
    29341 acaggcattg atgcgagggc tttatcctca tccgcctact ggacaagtag atgtgaaaca
    29401 attgatctat atgctcacgg tatttgaaag tacgctctat acgactaaaa atgaaatcac
    29461 tttatttaca gatggtcgtg aaaaattcga tgcgctgatt gaagatatca agcaagcaga
    29521 agaccatatc cacttccagt attatattta tcgcagtgat gcattaggtg aagaagttcg
    29581 agatgcattg acagaggcgg caagacgagg ggtaaaagtc agagtccttc ttgatgcatg
    29641 gggttccaca caagtttctt ccagcttttt tcagaatttg aaaaaagcag gcggagaaat
    29701 cgcatttttc tttcctctat ttgttccgta tattaatcct cggatcaatt atcgcaatca
    29761 tcgtaaaatc gtagttattg atgggaaaat cggatataca ggtgggttca atgttggaaa
    29821 tgaatatcta ggattggtaa agaaatttgg ttattggcga gacaatcatt tgcgtattta
    29881 cggagaagcg gtgtatatct tgcaaaaccg ttttttgatg gactggaatt ctcagcatac
    29941 aaaagaagta ggctattctc ccaaattttt tccgtccatt cactctactg gtgatatagc
    30001 tgttcaaatc gtgacaagcg gaccagatac cgaacatgaa caaatcaaaa tgacttattt
    30061 gaaaatgatt tcgttagcca aacgggagat attgatccaa acgccttatt acataccgga
    30121 tggatcgatt catgaagcac tgaagttggc tcttctttca ggcgtaaaag ttcatatcca
    30181 aatacctaac aaaccagatc atcttctcgt ttactgggca acgtattctt tcgctgcaga
    30241 gctgatcgag tatggagcaa ggatcgaaac atatgagaat ggatttattc atgcaaagac
    30301 gatgattatc gatggtggca ttgtttcagt tggctcagca aatatcgatg ttcgttcatt
    30361 tcgcttggac tttgaggtca atacactgat ttatgatgaa cgaatggctt cacgtgtaag
    30421 aaaagcattt tttgaagact cgaaaatttc tacgcatctc acaaaagaaa tgtatgaaaa
    30481 ccgaggaata atcatcaaga tgaaagaagg attagcaaga ttgatttcgc cgctccttta
    30541 aaacacaaaa aggacatgag aaccatcaac agatggagat ctcgtgtc
//
LOCUS       DAZKPE010000030        30358 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000030 DAZKPE010000000
VERSION     DAZKPE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.030"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            282..3875
                     /locus_tag="ACG930_001490"
     CDS             282..3875
                     /locus_tag="ACG930_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0518654.1"
                     /translation="MIRNKKLCLKVALLAVFCQVFFLVGSLTTQAEEITQGTTVSQVS
                     PTSNEVEVQSDLPKETAKEEISTEFVPPTEAPSMNEKSVLDETIGKSQQPGDSPVVAE
                     EIPIETPEVQTIFEKENSSEKSCSTVINEGTESVQSEDSKEATTPIELTKEEMNSNTS
                     LSSEKEEKTALSTESHEPELKKVEESGDTQKEKIKKEAVSSTSSKEVTLIVPQTARSA
                     RVRRATNTAVLGGRKIDWGENIGVISSANNPNFTLNYMVRFEINGQVAFCIEPGVAAA
                     EGQVYTATALENYLKDLNIRKKTSLISYLGYVTSKDKSDEQYIAAQFMIWEVLGTKIP
                     IKNIRIDYDRRKAEIQRLLNNFDVRATFHNQTHTVKIGETLKVKSGNDFLQRVKDIQK
                     PKGVNVSIHDNEVWITITKESPEKAKIHFNQIEALGVPLAYRRPGAQTIGVLNPFVPG
                     DSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQANGKKIKEITLKNING
                     KVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNTIAKDQVIKGTIDLV
                     KVANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTVVFDTY
                     ILSETKGKEGYKLFEPFEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKVIALAG
                     TQFKIWDKYANNGKGGYVSMALPNDTEVSDIFTTNEKGYFVTTDTLKYGKNRYELREI
                     KAPEKYVLNKTPYVFSVTDDTNTIQLIYFANRLAKANVEVFKYDTSTNFDQKTAIAGV
                     EFDLFKKDETGTTFVGTFKTDKKGKINVKDLLVGDYFFKEVKPLAGYLALDKDVPFTV
                     TVDKDGTVIALEVENKRIPPKIGTTAIGKYTNQQKVTPLKKVTITDTVKYSNLIIGKT
                     YTVNGVLMDKEESITAGKDVPLLVNGKQITASKVFVAKNPNGMISLDFVFDASALAGK
                     EIVVFENVYRDGRLVASHTDIHDKGQTVRIVNPMIHTKATGQNGEKQLQALPNQKVKE
                     LVQLNDLIVGQTYKVLVQGYITPDGVKLDGTSAEKIFKADKTTLEFLFEFLVDGRKLA
                     GKGLSFAEWLEAQSEPKDENDYEVRFEQIANHNVDLKSEDQTVYFVEVPKVPEPKIPE
                     KSQPFKEVKQASVVPMLPKTGSEDTVLWMIIGVLFVLAAGLTFYELRKVKD"
     gene            3975..4913
                     /locus_tag="ACG930_001491"
     CDS             3975..4913
                     /locus_tag="ACG930_001491"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0518655.1"
                     /translation="MKKKERKKRMKKLFFACLFSSVVLAGGINVFADEIGITPVTPPV
                     IEETTPVVPIPDISKIDESVPDQPTPVDPDISSEVTEPTTPVVPDITENSENETPVVS
                     PSTGETTNDKDTTPTTSESYSGTSSVDNDSKIDDFSSSSTTIDTPKETEKKNDLGAPK
                     NLTPENHIKTVSEKEMTVSVSSDGKIVQGTGTEKSIPIVTSNLEEINHVPTSETPLQV
                     ATGQAIVGVQDGVPLVQDNQGNLVEDLSIPVKKLPSGNIEIKTIDGKTKVLPKTGEEL
                     QISLTILGSLLTAVTGGIFYGKKQWRHLRHMFKKTI"
     gene            4932..5282
                     /locus_tag="ACG930_001492"
     CDS             4932..5282
                     /locus_tag="ACG930_001492"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518656.1"
                     /translation="MGLSYVAISQEEVLGKCFNQKHVGSTGERDHRGNMKKVEWEIFQ
                     MNSEKMGEIEVRVAVGGAPKAMRYNAEVLLANPRISRRADVRNIGNDGETNKIARNRF
                     YLLVDRVEVKGGNN"
     gene            5282..5713
                     /locus_tag="ACG930_001493"
     CDS             5282..5713
                     /locus_tag="ACG930_001493"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF961 family protein"
                     /protein_id="HFQ0518657.1"
                     /translation="MTLEFDQGIVPGLVKETLGEIYFVKAQRPRMLYEDNENTGEIKE
                     RPVEFSSATQETMFVVNFPPKTNLDGLSFGDVVELEEVEFRFWISIDRESMSNRAEND
                     LKVSALRYKKTGKNVFQTSSSTRATYVKEKQDSNKESAKKE"
     gene            5981..7300
                     /locus_tag="ACG930_001494"
     CDS             5981..7300
                     /locus_tag="ACG930_001494"
                     /inference="COORDINATES: protein motif:HMM:NF013727.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFQ0518658.1"
                     /translation="MFQYKGIRIRNRHKYASERFIFYLMLPVLLLMSGFFSLFYTTIT
                     WEWCCIYWIIAFGLAGLFAYMCLYFYFYNVYQRLVHKGKLAKMIHSRRLILERVLKNG
                     RRKVVYYPKIFYHYKNGLIHVRLPLDLGPFQDRFNEMAGQLEEAFFCDLVEEQREKNY
                     ICYTFLYDVEKNRIGIRDITVKDGIITLMKNVQWAFNKAPHAIIIGSTGGGKTYFIMS
                     LIYALLPYGTFDICDPKRADLASLEKIPIFKDQVFYGGGILSCLINLAKETANRYDFL
                     REQPEYELGYDYTYYHLTPHFLVIDEWAAYYASLDTKEKKKAMGCLNQIALMGRQCGV
                     FLILGTQRPDTKYLDGAIRDNFGLRVTLGRVSKAGYKMIFEHTVKSLFNKPIKGRGYI
                     DSGTDQVREFYAPFIDITRFNFFAEFKQLSDQLMAEKIKETKEGKNV"
     gene            7293..7457
                     /locus_tag="ACG930_001495"
     CDS             7293..7457
                     /locus_tag="ACG930_001495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518659.1"
                     /translation="MYEEIPATCGTRLGIKDLMIDSFLAIVFSEKRLSFFINKKVENR
                     WRVERMYPTS"
     gene            7996..9171
                     /locus_tag="ACG930_001496"
     CDS             7996..9171
                     /locus_tag="ACG930_001496"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0518660.1"
                     /translation="MDGTQLKQMRLSRNLTQKLVADTLGWPQSFLSMIENDQRSCSKE
                     QEEALCEFYANFSSFTSLEIKFDYVRVRVPTNDTKTVVEEILGMDFNSFFYAETRLYG
                     YIEMYQKGMIRVLNSKKGDDKGVLIELSGQGCRNYESVLDERNDSWYQFFTRCVSFNG
                     VSRRIDIAVDDFEELFSLHEFAQKLNRGEFDSKFRTWRFQEEKQLLDNLSSGLSVYLG
                     SSQSLMYFCFYQKNYEIAKKQKLPLEEVEVKNRYEIRLRDAKAVSFIEQYLNKVDFSD
                     LTMGILANQLIMFEGEKNTNVWKPWGKLIQNVGKVNLTVTPEKPNYNRKLMYLKTQPA
                     RTMKIVKTVDEILGLNRFGEILEETELREQDEKIVEDEVRAVYEYIQENPDAIHYLL"
     gene            9676..9873
                     /locus_tag="ACG930_001497"
     CDS             9676..9873
                     /locus_tag="ACG930_001497"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518661.1"
                     /translation="MGQYFLTGVWYVLKLVIILGIAYICFRILLSGEGMPTPKDFIIS
                     VLNFVADQIQVIIHWAQQRFG"
     gene            complement(10270..10818)
                     /locus_tag="ACG930_001498"
     CDS             complement(10270..10818)
                     /locus_tag="ACG930_001498"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518662.1"
                     /translation="MSILQPFGEPIERTEFIQHYMKLFVQVIKHTHQIDEFYSKEIEY
                     LLAEKQKIALLYDYFVEMYDRAPDYFYLSDTLTTNFLAKEHLFASHTKNLMCVEHFVN
                     TYLHLLKIQKICTFEAFQTDYLFILDREAYHAKLAFEKQNQAIEGYPELRIQNNSFLQ
                     QRLLKQLINGFHQRNKAYQKDQ"
     gene            complement(10874..11167)
                     /locus_tag="ACG930_001499"
     CDS             complement(10874..11167)
                     /locus_tag="ACG930_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518663.1"
                     /translation="MLRTNAIPIVDSYDRNTNNYLGSFEQTDENILNYVAGLSPFESV
                     RLVEHTTDTLILTTIGYFFDQVSDQQWLQQILPKLIAKQTGKSTIEAVKIFFY"
     gene            complement(11360..11701)
                     /locus_tag="ACG930_001500"
     CDS             complement(11360..11701)
                     /locus_tag="ACG930_001500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518664.1"
                     /translation="MKANTPYKVGDIFYSSWGYEQTNVTFWQIIKLTKKTAWFRPIKK
                     QTVKNYTSMSGETMPIPNEFIDYPLARTKDSIVRKRINPALYPNELYGNRSWDTFYRY
                     DNQPVYESSYY"
     gene            12202..12354
                     /locus_tag="ACG930_001501"
     CDS             12202..12354
                     /locus_tag="ACG930_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518665.1"
                     /translation="MKKKGIPYSPKPRNAFERGLFKYFEGERDQEEKEKNQKKKSSQE
                     KENIEK"
     gene            12376..12843
                     /locus_tag="ACG930_001502"
     CDS             12376..12843
                     /locus_tag="ACG930_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518666.1"
                     /translation="MKKSLIVLIVGLSIFGSVLFIGNSLFSNKDVTEQSPASTTEEVS
                     PELLLETDVLDTKKPETIPSENELYQGDLSFEYADPEKPYVLTIRFIDKANHEYVGPD
                     KKPLKREKELILGKAKGVVHVVVKANRSMLTHIQKLKDIQVSMTLNERNEKTE"
     gene            13089..16052
                     /locus_tag="ACG930_001503"
     CDS             13089..16052
                     /locus_tag="ACG930_001503"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0518667.1"
                     /translation="MLKKVLRFGVCISIWLVTSSTFVPSMIAVADSVAIQETIASDSE
                     GEEKLTERSDDASDGQTEKVEVQKTETTQTTVSSSSDESSDLTQSSEETAPEEVDEST
                     EESSDPQEQTISHEEETKEAVDSSTIDFEGTRSSESFGKHTSPSIDKPNEKIAEPVSS
                     NEGAVVSRRSRRDLSAVSSNHPEEEPVVAFDEKAFDAAIDQYIDHATEEELGLVINSS
                     NEKELADALEYLLLNQLDESFGVEELDELKKFLTADEIERLENESSLETFEQLLTQYY
                     NDREQKLEEGAAFSDFFLASTDEEIDRMLEVKDEQALEQVISEISASRNSQTSGKRNK
                     RFLVIPLLVKGAMLVIGAGVAAYSSHQFYKTMEAQRAEKKRMVERWRYHEQQAQKRHQ
                     AAQQARAKAVARAKLQAAARAKAQATQRARAQAAAKARKQAQNWAKQQAAARARAQAA
                     ASARRKSNASYVPPVTRPKPVIKAQPKVPAKPVAKPVTKPTSPAKPKPTTTPKNTMHQ
                     VRAGESVWSISHKYGISMNDFIKWNKIKNNLIHPGQQVIVKQPASTSKPVSKPATKSS
                     TPATYKVKAGDSVWGICEKYGLSVSKFVQWNKIKNNTIHPGQVMHLQEPKPASKPAPK
                     TSPTTNTTYTVKAGDSVWLIANMHGISMNDLVKWNKIKNNTIHPGQKLTVKQPVSSGK
                     TTTKVPASTNPVTHKVSYGESLWLISSKYGVTVDELRKQNGIKGDLIHPGQVLVVKKG
                     MTTSHSTPAGKSGTSYTVKAGDSVWLIANRYDVSMDDLVKWNKIKNYTIHPGQVLTIQ
                     TIVSTPAKPAITTTPKVESKPAITTTPKVESKPGVTTTPKVDEKPVITTLPKVKEQPV
                     VTTVPKTESEVLVEKASGSTGTVWDDIKGTQPPREGTTIPKSFEIIVNGEKLWVNPNG
                     TKHMVEYSTRNLSHGQKLTEQQLLRSFQGAVEQATSTGIKFETKIIIDNWELIFSPAR
                     EAGQLPVIKHAVYLP"
     gene            16071..16583
                     /locus_tag="ACG930_001504"
     CDS             16071..16583
                     /locus_tag="ACG930_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518668.1"
                     /translation="MKIKSYEDKLVKDDIEVDYYVPITVSFPENDDKYNLGEFYYYRF
                     VNEYESFVEIKINSVTQKIVEVVFTSINDIEDSNLFIGEYAEKNPVIQTDIFDENSII
                     TKESGFKISREHKKLCFKLDKEKMDSVVKMSNHVSLFLNEDSEIIGLEFSSFSDNEWA
                     ELNESIKSTT"
     gene            17105..18172
                     /locus_tag="ACG930_001505"
     CDS             17105..18172
                     /locus_tag="ACG930_001505"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0518669.1"
                     /translation="MAKPSTPATYKVKAGDSVWGICEKYGLSISKFVQWNKIKNNTIH
                     PGQKLTVKQPVSSGKPTTKVPASTNPVTHKVSYGESLWLISSKYGVTVDELRKQNGIK
                     GDLIHPGQVLVVKKGMTTSHSTPVGKSGTSYTVKAGDSVWLIANRYGVSMDDLVKWNK
                     IKNYTIHPGQVLTIQTIVSTPAKPAITTTPKVKAKPAITTTPKAESKSGVTTTPKVDE
                     KPVITTIPKVKEQPVVTTVPKTESEVLVEKASGDGSRLDINIKNFEIKNKHLNSSTAK
                     RARKFNVSSAEEANKIVQDALKNGKLVEAIPNGVGSQGQNSFSSIIDTGKVIGTKGET
                     HIKIVYDELKNVWTTYPVPKP"
     gene            18189..18575
                     /locus_tag="ACG930_001506"
     CDS             18189..18575
                     /locus_tag="ACG930_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518670.1"
                     /translation="MIDKQITNILQSYKKQQIFKIEDFLLSEIDEDNLQETIDFVVSD
                     DVSKKINFSDELYDGNEYEGVFLEGNQYLLSSSEGKVMIIDMLSEAHGVNIKDTRVQF
                     DEEKFIKLITNKKEILNWIKNYKVDK"
     gene            19600..20400
                     /locus_tag="ACG930_001507"
     CDS             19600..20400
                     /locus_tag="ACG930_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFQ0518671.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKVSGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTQNLGMIKEK
                     DEEEMLWKVDGIEYVLDKAEHLVKNAKESLLIQVWHENLTDSLLKTLQQAEKRVDKFV
                     LILFSSSHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESSEELKAKYGEDFEGIRKIY"
     gene            20416..21294
                     /locus_tag="ACG930_001508"
     CDS             20416..21294
                     /locus_tag="ACG930_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFQ0518672.1"
                     /translation="MIRNILLALIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFITFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGVKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAAFLIFMGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFDEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYVLKWIVILVLLYS
                     AYTMLGSQLKKVSAAN"
     gene            21307..22287
                     /locus_tag="ACG930_001509"
     CDS             21307..22287
                     /locus_tag="ACG930_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFQ0518673.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENLKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFDRASRFAEEMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVNKAKENNLGKLIY"
     gene            22809..23027
                     /locus_tag="ACG930_001510"
     CDS             22809..23027
                     /locus_tag="ACG930_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518674.1"
                     /translation="MNFFQNVFTDFVGDFKYLIMLAMLGGAAYIAFERKASKAIPLIL
                     VLAVAVWLVGDTSGVFNWILDRMRSWGR"
     gene            23029..23436
                     /locus_tag="ACG930_001511"
     CDS             23029..23436
                     /locus_tag="ACG930_001511"
                     /inference="COORDINATES: protein motif:HMM:NF024062.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFQ0518675.1"
                     /translation="MSEIRNWTKIWYIERVFYKLWDGVALPRPVTQTFAIWFGIGFFG
                     GIFRIFPFVMEHTITRQFFCPWLFAFLMTRKQFQGRKPYNYLASFLLFQCRSKESFHG
                     QWVKPIEKKEIKRGIRCVVRYGGEKDATTKTSA"
     gene            23411..25948
                     /locus_tag="ACG930_001512"
     CDS             23411..25948
                     /locus_tag="ACG930_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0518676.1"
                     /translation="MRLPKLVPKIPFYYLEDNLVFGEEDRVYAYYEFPMYSYSFVGED
                     QAYQLQQAIMRLIRQSHSSHVRFFFCTNEEKIEKTIKSSKELVRSKGELKTIAYQHLE
                     GVQHILEELHGKYIQNVCWYVGIELVLEEIAPKEAHWLKEFRIAAKDFFHRSNARLFG
                     DFETIPNEKIQRYKRLENLLYNRISKYFRLRKTTPEDMVFLVEHLEGKKEQSLDEVMY
                     RPNSFKEETNTYTYHYDVLNLASAGITEKKNYLILEQGTEKEYITYLSLSRMTRDLVF
                     PFQSEIYYFLQSELDFPIDSWLDVNLLDNRLALAKVRGKKSDLSDIYESGMSVGKDVG
                     NNVREAYQSANELEQKLEDTREDLYVLSLNVRVSGKTYDEMLKRVSDVRNFFDVYSMY
                     LEVPCNVQLLLHFGSYPAGRRVIEDYRQYVGAEFIASLGIGATQQLGDGCGIPIGFNA
                     ETGIPVFIKPWLAAQGIKGTVTNTLAKALIGSLGGGKSLTENLLLFWSVLFGALAFCI
                     DPKSERSNWSEDLPYFAPYLKTVNITSEKENIGLLDPFQLMRRKKDQESLALDVLTYI
                     TGVSIRDEDRFPLLQRAVKTVSDFEGTKGLLLVIQELYAQEAATAQRLAKHIESFKEL
                     SIAGLLFGDGTNQQGLNLDAKCNLALVQDLTLPDSETVPEDYNSSEILSIAIMMSLAT
                     YALDFIKQNRKIYKAVGLDESWAWLNVAQGKILGDKLVREGRSRNAGIDFSTQNTDDL
                     GDEKMRSKIGLKFIFRSNDREEITKALSFCGISVTEENIQRVKNLENGECLFCDIHGN
                     IGILYVYYWFEDLFHAFDTRPPMEETYEEEEYKDEILEKLVEEIEVN"
     gene            25949..27970
                     /locus_tag="ACG930_001513"
     CDS             25949..27970
                     /locus_tag="ACG930_001513"
                     /inference="COORDINATES: protein motif:HMM:NF046089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFQ0518677.1"
                     /translation="MKQWYSKVSFLITRRKLVFISLVIMMGVFFFHPSLVEAAGWIKE
                     TLGGKNAVYDFETYPLDNYNLDFFVDTSWNWLPWKWGEGISNTVIYGIFAVTNILWML
                     NVYLCYFLGFLVQEAFELDFLSELIGSLSHTIQNIAGMNRTGTLSHGLVPFFGGLLIT
                     LAGCSVVYQGIVKQHPTQAIQQAVTFLFTFICCGVFFMNTNTYLEKANGVQKEINSEM
                     LTIAKNLLPEQKEKPDAIKAIRENLFAIQIKQPWLVMQFGDSDIKTVGEERIINLLKE
                     SPYDEGEQRNKLVEEEVTKQKNGHLSVQKVYLRFGMVFLTLIVNIVISMSVLVLIVIL
                     IASQVLFLLFIGFLPVAMIFSLFPNSGSLLGNALQKVFQLLFTKMGILLILTITFSIS
                     HELNHLSKDKGMIWTSFLQVTLWLSVSTRVNELLGWMKIGGVQTRAGDRTGRFLRGMM
                     LGTMGQKMIRGIGENFVGGTAGGVAGQMISKSMSGQRSIASTPLIERVGKKVSAMTEL
                     PATIESRAEQWKRTIQYVPTNAQYKAQKMKYDYFSGRMNESERQTRARNLANERQKNF
                     YEARKDALQLEQQERKQRAMRSMAHQTGKTQVTSGKLQTRKSAMIGRTEQFPTIEKRS
                     NISNIAKNKKLSKQEHPIHERSTNRKIETPVRWTSTSRQNARKGRTKKE"
     gene            27982..28905
                     /locus_tag="ACG930_001514"
     CDS             27982..28905
                     /locus_tag="ACG930_001514"
                     /inference="COORDINATES: protein motif:HMM:NF024056.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFQ0518678.1"
                     /translation="MFPRKKKLSILSEQETRLKGKKDKKKESYKGARKRRFLFFVGWS
                     FLVFSVCFGVYNNLTSQDTHTIHETKVIDKQLKDMTGIESYVKNFAFLYFTVSLESDQ
                     QINRSKAVESYLADGLQMDNEIDKDIETNVKVKNVSIWAIEEHESKKHTFVVMFHVLL
                     EIEKEFKERVYKVEVYRNELSYAIVKLPIVASNVKKATIKVDTRFETTSISRKEQEEL
                     EKFLYTFFRIYPKANAEELKYYGTTLLPIQQPLAFEELSNLQVAKKEGRYEIHCNILY
                     QDQETHLWFTMYYEMSMKQLENGNFRIEAIH"
     gene            28977..29996
                     /locus_tag="ACG930_001515"
     CDS             28977..29996
                     /locus_tag="ACG930_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0518679.1"
                     /translation="MSSGESKHMDSAVGVTHTGEYIETLPIFSEIKGRGPITDEHAQA
                     AVGAAVKYQLLPSVILSQLGYESAYGQSQSGRNDTNFFGITWFPGCPYPQGSARGIGG
                     SEGGFYMKFPNLNACYDYYGFMVASQSNFNQCVGNKDPGSCLLILGRGGYAAAGITEG
                     SSYYQGAISIIKSYNLTEYDAFAIKHWNSLPIKKTSLIAGKSKGNAKVLDRIIGRPVN
                     NGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGEDYNWATYGWQVIMNPKPSDLQAGDV
                     VNWQAGGALSPGIYGHTGIITDVSNSGQSFSTVEQNAEQGRIMARYQRGYNQAKIRSL
                     VRKVK"
     gene            30047..>30358
                     /locus_tag="ACG930_001516"
     CDS             30047..>30358
                     /locus_tag="ACG930_001516"
                     /inference="COORDINATES: protein motif:HMM:NF042930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFQ0518680.1"
                     /translation="MKKYYFFFLSCFCLFGLTSCGWIFSEEKTEVSLISKEKMIQAES
                     SSKESKRNQEDKTECNISEEIQYLLKNFGRKWVNYTDIYERNQSVKNYLTDRCIKENG
                     ID"
BASE COUNT        10636 a         4567 c         6228 g         8927 t
ORIGIN      
        1 tagagatgtg aacgaaaaat atttatttct attacaaaag gtaaaaaatt tgatttaaaa
       61 gctaaatgta cagatgagtt ttgaattttt ctccttcaaa ttcaaaatga gagtagtagg
      121 tatgatagaa atatatcaaa tattaagata gatacaatat gcataatagg ctatgcttct
      181 ttagattttt tgattaagaa cacaataaat agtttacgtc gatacttatt aagttatcga
      241 cgtttttttt ataaaaaatt tataaaagga ggtttcttga tatgataaga aacaaaaagc
      301 tttgcttgaa agttgcttta ttggcagttt tttgtcaagt attttttttg gtaggctcac
      361 tgacaacaca agcagaagaa ataactcaag gaacaactgt ttctcaagtt tctcctactt
      421 caaatgaagt tgaagtacaa tccgatttac caaaagagac tgccaaagaa gagatatcga
      481 cagaatttgt tccaccaaca gaagcacctt caatgaacga aaaaagcgta ctcgatgaaa
      541 ccatcggtaa aagccaacaa ccaggagata gtccagttgt ggcagaagaa ataccaatag
      601 aaacacctga agttcaaaca atttttgaaa aggaaaattc atcagaaaaa agttgttcta
      661 ctgtaataaa cgaaggaaca gaatcagttc aatcagaaga ttcaaaagag gcaacgactc
      721 cgattgaatt gacgaaagaa gaaatgaatt ctaatacttc actttcttct gaaaaagaag
      781 agaaaacagc tctttcgaca gaatcccatg aacctgaatt gaaaaaagtt gaggaatcag
      841 gtgatacaca aaaagagaaa ataaaaaaag aagctgtttc ttctacttct tcaaaagaag
      901 ttacattgat tgtaccacaa accgctcgaa gtgcacgggt gcgacgtgca accaatacag
      961 cagttttggg tggtcggaaa attgattggg gcgaaaatat tggtgttatt tctagtgcca
     1021 ataatcccaa tttcacttta aattacatgg ttcgttttga gattaatgga caagtagcat
     1081 tttgtattga acctggtgtc gcagccgcag aaggtcaagt ttatacagct actgctttag
     1141 aaaactattt gaaagattta aatatacgaa aaaaaacaag cttgatctct tatttaggat
     1201 atgtcacaag caaagacaaa tccgatgaac aatacattgc ggcacaattt atgatttggg
     1261 aagttttggg cacaaaaatt ccaattaaaa atatccgtat tgactatgat cgtcgaaaag
     1321 cagaaattca acgtttgctt aataattttg atgtaagagc tacttttcat aatcaaacac
     1381 atacggtaaa aattggcgaa acgttaaaag taaaaagtgg caatgacttt ctacaacgtg
     1441 taaaagacat tcaaaagcca aaaggtgtta atgtatctat tcatgataat gaagtatgga
     1501 ttacaatcac aaaagagtca ccagaaaagg caaaaattca tttcaatcaa attgaagcat
     1561 taggcgtgcc attagcgtat cgtcgtccag gtgctcaaac aattggggtg ctgaatcctt
     1621 ttgtacctgg tgactctgtt gtcaatttga ccattttgaa acaaggaaac attcgcgtct
     1681 ttaaagaaga tgcagaaacc ggtgtgaaag cacaaggtgc agcttcttta gaaaatgcag
     1741 tgtatggctt gtatcaagca aatgggaaga aaatcaaaga aattacattg aaaaatatca
     1801 atggcaaagt acaggcagaa atcaaagatc ttgatcctgg taaatatgtt ttaaaagaga
     1861 tcaaagcacc aaaaggttat gtactttctg atgaagcaat tgaaatcgtc gttgaacctg
     1921 gaaaaactgt caatacgatc gcaaaagatc aagtgatcaa aggaaccatt gatttagtca
     1981 aagtcgcaaa taaagattta gtcgattcaa ccaatccaga caacaaaccc aaattagctg
     2041 gtattgaaat ctctttgacg tcaaaaacaa ctggaaaagt ggtgaaaaca gttgtgacag
     2101 ataatgatgg ttacgctact tttggtaaaa ataccgttgt ctttgatacg tacattcttt
     2161 ctgaaaccaa aggaaaagaa ggatataaac tatttgaacc attcgaagtc acaatttctg
     2221 aaaatggaca aaccttccat tatgttttag aagacaaagt aatcgaacaa cgtcttaaag
     2281 tggtgaaagt ggatcaagaa acagggaaag tcattgctct agctggtacc caattcaaaa
     2341 tttgggataa atacgcaaac aatggtaaag gtggctatgt atcgatggca ttaccgaatg
     2401 atacagaggt ttcagacata tttacaacaa acgagaaagg gtactttgtc acaacggata
     2461 cattgaaata cggaaaaaat cgttacgagt tgcgagaaat caaagcacct gaaaaatatg
     2521 ttctaaataa aacgccttat gtcttttcag taacagacga caccaatacg attcaattaa
     2581 tctacttcgc taaccgttta gcgaaagcca acgtagaggt tttcaaatat gatactagta
     2641 cgaattttga tcaaaaaacg gcgattgctg gtgttgaatt tgacctattc aaaaaagatg
     2701 aaacaggcac aacctttgtt ggtacattca aaacagacaa aaaaggtaaa atcaatgtga
     2761 aagacttatt ggttggcgat tacttcttta aagaagtgaa accattagca gggtatctgg
     2821 ccttagataa agacgtacca tttactgtaa cggttgataa agacggtaca gtgattgcac
     2881 tagaagtgga aaacaaacgg attccaccta aaattggtac tacagctatc ggtaagtata
     2941 caaaccaaca aaaagtgacc ccattgaaaa aagtaacgat tacagacact gtaaaataca
     3001 gtaatctaat catcggaaaa acttataccg tcaatggtgt tttgatggat aaggaagaat
     3061 ctatcacagc aggaaaagac gtaccgttgt tagtaaatgg taaacaaatt accgcaagta
     3121 aagtgtttgt cgcaaaaaat cctaacggaa tgatttccct tgactttgtc tttgatgcta
     3181 gtgcattagc tggaaaagag atagtcgtat ttgaaaatgt ctatcgtgac ggacgcttag
     3241 ttgcgtctca tacagatatt cacgataaag gacaaacggt tcgtattgtg aaccctatga
     3301 ttcatacaaa agcaacaggt caaaacggcg aaaaacaatt acaagcttta ccaaatcaaa
     3361 aagtgaaaga attggtacag ttgaacgact taattgttgg tcaaacgtac aaagtgctcg
     3421 tacaaggtta tattacacct gatggtgtga aattagacgg tacaagtgct gaaaaaattt
     3481 tcaaagcaga taagacaact ttagagttct tatttgaatt tttggtagat ggacgtaagc
     3541 tagcaggcaa aggattatct tttgcagaat ggttagaagc ccaaagtgaa ccaaaagatg
     3601 aaaacgatta tgaagttcga tttgaacaaa tcgcaaacca caacgtagac ttaaaatcag
     3661 aagatcaaac ggtttatttt gtagaagttc caaaagtacc ggaaccaaaa attcctgaaa
     3721 aatcacaacc ttttaaagag gtgaaacaag cttcagtagt accaatgttg ccaaaaacag
     3781 gatcagaaga tactgtatta tggatgatca ttggtgtgct atttgtttta gcagcaggtc
     3841 ttacatttta cgagttacgc aaagtcaaag actaagtagg acaaacaagc ggttagatgc
     3901 ctaatcgctt gtttggtttt aaaaaagtta ttgcataagt aacctttgaa aagataagaa
     3961 atgatctttg ttttatgaag aaaaaagaaa ggaaaaagag aatgaagaag ctatttttcg
     4021 catgtttatt tagttccgta gttcttgctg gtggaataaa cgtttttgca gatgaaatag
     4081 gtattacacc agttacgcca cctgtgatag aagaaacaac acctgttgtt ccaattccag
     4141 atatttctaa aatagatgag tctgttccgg atcaaccaac tcctgttgat ccggatatat
     4201 cttcagaagt aactgaacca acaacacctg ttgttcctga tataacggaa aattcagaaa
     4261 atgaaacacc agttgtatcg ccttctactg gagaaacaac gaatgataaa gatactacac
     4321 caactaccag tgagtcttat tcgggaacta gttcggtaga taatgattca aaaatagacg
     4381 attttagttc ttcatctact acaatagata caccaaaaga aacagaaaag aaaaatgatt
     4441 taggagctcc caaaaattta acacctgaaa atcatataaa gactgtatcg gaaaaggaaa
     4501 tgactgtttc agtcagttca gatggaaaaa ttgtacaagg aacgggtacc gaaaaatcaa
     4561 ttcctattgt gacaagtaat ttagaagaaa ttaatcatgt cccaacatct gaaactcctt
     4621 tacaagtagc gactggtcaa gcgattgttg gggtacaaga tggtgtacca cttgtacaag
     4681 ataatcaagg gaatttggta gaagatttat ccattcctgt aaaaaaacta cctagcggca
     4741 atattgaaat caaaacaatc gatgggaaaa caaaagtatt gccaaaaaca ggtgaagaac
     4801 ttcaaattag tttaactatc cttggttctc ttttaacagc agtaaccggg ggcatttttt
     4861 atggtaaaaa acaatggcgt catttgcgtc atatgtttaa gaaaactatt tagtaaggag
     4921 agagaataaa aatgggttta tcttatgttg caattagtca ggaagaagta ttgggaaagt
     4981 gttttaatca aaaacacgtt ggctcgacag gtgaacgaga tcatcgagga aatatgaaga
     5041 aagtagagtg ggagattttt cagatgaact ctgaaaagat gggagaaatt gaagtgcgtg
     5101 tagctgtcgg tggtgcgcct aaagccatgc gatacaatgc agaagtgtta ctggcaaatc
     5161 ctagaatttc tcgtcgagca gatgtacgaa atattggaaa tgacggtgaa acaaacaaaa
     5221 tagcacgtaa taggttttat ttgttagtcg atcgtgtaga agtaaaagga ggaaataact
     5281 aatgacacta gaatttgatc aaggaattgt cccagggttg gtaaaagaaa cactaggaga
     5341 aatctatttt gtcaaggcac aacgtccacg tatgctgtat gaagataatg aaaacacagg
     5401 agaaattaaa gagcgtccag ttgaattttc aagtgctacc caagaaacaa tgttcgtggt
     5461 gaattttcca ccaaaaacaa atttggatgg attaagtttt ggcgatgtgg tggaattaga
     5521 agaggttgaa tttcgatttt ggatttctat tgatcgcgaa tcaatgagta accgagcaga
     5581 gaatgatctg aaagtatctg cgcttcgtta taaaaaaacg ggaaaaaacg tttttcaaac
     5641 gtcttcctct actcgtgcaa catatgtaaa agaaaaacaa gactcaaata aagaaagtgc
     5701 aaagaaagag taatggtttc cattgctctt tcttatttta aagctagaag aagtagctga
     5761 tgtggagaaa attgaattgg ctggctatat tattgggata aatttttgaa tttttaagaa
     5821 tttagatagt ggttagatac gattgattct ttgtgtattt tgtattattt aagtattgtg
     5881 tggtatttac attaagttaa tattgatgtt gttagtgtta atgaaggttt tcttttatcc
     5941 aatacattag tcactctatg atgcgaggag atgagaataa gtgtttcaat ataaaggtat
     6001 tcgtattcga aatcgacata aatatgcttc agaacgattt attttttatc ttatgttgcc
     6061 ggttctgttg ctaatgagtg gatttttttc tctcttttat acaacgatca catgggaatg
     6121 gtgctgtatt tattggataa tcgcatttgg tttagctggt ctatttgcgt atatgtgttt
     6181 gtatttttac ttttataatg tttatcagcg attggttcat aaaggaaaat tagcaaagat
     6241 gatacatagt cgtcgattga ttcttgaaag agtattgaaa aatggacggc ggaaagtggt
     6301 gtattatcca aaaatttttt atcactataa aaatggctta attcatgttc gattgccatt
     6361 agatttaggt ccctttcaag atcggtttaa tgagatggct gggcaactag aagaagcctt
     6421 tttttgtgat ttagtagaag agcaacgaga gaaaaactat atttgttata cctttttata
     6481 cgatgtggaa aaaaatcgta ttgggattcg agatataacc gtaaaagatg gcataatcac
     6541 cttaatgaag aatgttcaat gggcatttaa taaagcacca catgccataa ttataggaag
     6601 tactggcggt gggaaaacgt attttataat gtctttgatc tatgcattat taccgtatgg
     6661 tacgtttgat atttgtgatc caaaacgtgc agatttggct agtttagaaa aaataccaat
     6721 ttttaaagat caagtttttt atggtggtgg tattttatct tgtttaataa atctagctaa
     6781 agaaactgct aatcgatacg attttttaag agaacagccc gagtatgaat tagggtacga
     6841 ttatacttat tatcatctaa ctcctcattt tttggtgatt gatgaatggg cagcatatta
     6901 tgcatcgtta gatactaaag aaaaaaagaa ggcaatggga tgtttgaacc aaattgcttt
     6961 aatgggtcgt caatgtggcg tgtttttaat tttaggtacc caacgtccag atacaaagta
     7021 tttggacggc gcgatacgag ataattttgg tttacgtgta acactgggaa gagtatccaa
     7081 agctgggtat aagatgatct ttgaacatac agtaaaatca ttatttaata agccgattaa
     7141 aggtcgtggt tatattgatt cgggaaccga tcaagtacga gaattttatg cgccatttat
     7201 cgatataaca agatttaact tttttgcgga atttaaacaa ctatctgatc aattaatggc
     7261 tgaaaaaatc aaggagacga aagagggaaa aaatgtatga agaaatccca gctacatgtg
     7321 gaactcgatt aggaataaaa gatttaatga ttgactcttt tttggcaatt gttttcagtg
     7381 agaagagatt aagcttcttt atcaataaaa aagtagagaa tcgttggaga gtagaacgta
     7441 tgtatccaac gagttaactg attggttaca gttgccttat gacaattatc gaaggcgaat
     7501 atgacgggtt tttacttcaa ataaaagtgc tcgatcctat agtgaccaaa ttgtcgaaaa
     7561 agcagcggaa cagcctgttt tttatggacg attcaaagga ctttcctgtt cttatgttaa
     7621 aagtaaagac cggtctcgac tgtacctaca agtagaggat attaacttgt cctttgcgtt
     7681 gccagaaaat taaatttgtc ctcattagaa tacggaagat gctgtgcgta tgctccacaa
     7741 gcaaacaagc ctcagggcgg aaggacgcgg aagcgtccta gcgttagcga aagccctgag
     7801 gtgcagggtg cgttgtgggg cgtgcgcgta gcgcacgcct aaaaccccca tattctaaca
     7861 ggggggtaga atttatattc ggtggcaaag atgggtgatt gaaacattga tataacacta
     7921 ttttgcttca aaaattttgt gatatttttc ttcgctttgt aacataaaat atcacaaaag
     7981 aaaggaaaga tatatttgga tgggacacaa ttaaagcaaa tgcggttaag tcggaatttg
     8041 acacagaaat tagtggcaga tacattagga tggccacaat cttttttatc aatgatagaa
     8101 aatgaccaac gaagttgctc gaaagaacaa gaagaagcac tttgtgaatt ttatgcgaat
     8161 ttttcaagtt ttacgagttt agaaattaaa tttgattatg tccgtgtacg agttccgaca
     8221 aatgatacga aaacagttgt ggaagaaatt ttgggaatgg attttaactc ttttttttat
     8281 gcagaaaccc gcttatatgg ttatattgaa atgtatcaaa aaggcatgat ccgtgtatta
     8341 aattctaaaa aaggtgacga taaaggagtg ttgatcgaat tatctggtca aggctgtcgg
     8401 aattatgaaa gtgtactgga tgaacgaaat gatagttggt atcaattctt tacacgatgt
     8461 gtctctttca atggtgtgtc tcgaagaatt gatattgcgg tagatgattt tgaagaacta
     8521 ttttctttac atgaatttgc acaaaaacta aatcgtggcg aatttgattc aaaatttcga
     8581 acctggcgat ttcaagaaga aaaacagttg ttagataatc taagtagtgg cttatctgtt
     8641 tatttaggta gttcacaaag tttgatgtat ttttgttttt atcagaagaa ttatgaaatt
     8701 gcaaaaaagc agaaacttcc gttggaagag gtcgaggtaa aaaatcgtta tgaaattcgc
     8761 ttacgtgatg caaaagcggt cagttttatt gaacaatact taaataaagt agatttttca
     8821 gatttaacga tggggatttt agccaatcag ttaataatgt ttgagggaga gaaaaacaca
     8881 aatgtgtgga aaccatgggg aaaattgatt cagaacgttg gaaaagtcaa tttgacagtg
     8941 acaccagaaa agccaaatta taatcggaaa ttgatgtatt taaagacaca acctgctcgt
     9001 acaatgaaga ttgtaaaaac tgtggatgaa attttaggat tgaatcgatt tggagaaatt
     9061 ttagaagaaa cagaattacg ggaacaagat gaaaaaattg tagaagatga ggtgcgtgct
     9121 gtttatgaat atatacaaga aaatccagac gcgattcatt atttgctata aagcttgcga
     9181 taagatgggt gaaacatgat taaaacagaa gaccaatgat ggggagagta tatgattgct
     9241 tgttaacgat taataaaaga aacgatccta tgtgttggaa atgatctaca gttatttaaa
     9301 gaatatttag attatcaaca atcaatcaaa atgttacatg tagaaatagg ggaagtatta
     9361 agctaccgta ttagtgattc gttaaaatat tcgttgacaa agatttattt atatgcaaca
     9421 caagtatgtg gatatacgaa aaagcagtaa aaacaatgat gaaatatgac gatttgccaa
     9481 gtaagatatc ctagatttac aacaagtatt ggaagaaaaa ctatatctat atatgaaaaa
     9541 tagaggggaa aagaaatgat tcgattttta ttttctgtag gttggcattt tttgaaatta
     9601 ctgtttcttt tagtttgtat tgtctgtagt attatttggt tattaacact ttaaagaaag
     9661 gaatatgttg gaaaaatggg acagtatttt cttaccggtg tttggtatgt attgaaatta
     9721 gtgattattt taggtattgc ctatatttgt tttagaattt tattatcggg agaaggaatg
     9781 ccaacgccaa aagattttat cataagcgtg ttgaattttg tggcggatca aatacaagtg
     9841 ataattcatt gggcgcagca acgttttgga taaaaaaata tatttaaaaa atttaatgtt
     9901 tagaagtggg ctatgtgata gaaaatttcg agtataagtt atctagattg ccaaagaaaa
     9961 agggagctac acaaaaagag ctggctaata aattaggtgt caatgtacaa agcgcttcta
    10021 atgttgagga agataagagc taactacatt tagtaattta gaaaaaatag tttctttctt
    10081 tgatgcttca tcgattgaat tatttggtac gaatagggat cgaataattg cagatgttcc
    10141 attaatatta gaagatatgg ataatttatt taaaaaaatt tgaatgatct ttatgactaa
    10201 aaaagtaatc aaacaattaa aaaaagaagt ttctgttttt gatggaaaaa acctatcaaa
    10261 aagaaccagt tattgatctt tttgataggc tttatttcgt tgatggaatc catttattag
    10321 ctgtttcaac aatcgttgtt gtaaaaaaga attgttttgg atgcgtaatt ctggatagcc
    10381 ttcaatggct tgattttgct tttcaaatgc tagttttgca tgatatgctt cacgatctaa
    10441 aataaataga taatctgttt gaaatgcttc aaatgtacag attttttgaa tttttaacag
    10501 atgaagatag gtattgacaa agtgttctac acacataagg ttttttgtgt gtgaggcaaa
    10561 aagatgttct ttagctaaaa agttagtagt aagtgtatca gataaataaa agtaatctgg
    10621 tgcgcgatca tacatttcga caaaatagtc ataaagtaaa gcaatttttt gcttttctgc
    10681 tagaagatac tctatttctt tggaataaaa ttcatcaatt tgatgagtgt gtttaataac
    10741 ttgaacaaat aatttcatat agtgttgaat gaattctgtt cgttcgattg gttcaccaaa
    10801 gggttgaagt atggacatca ttctttctcc tttcactcaa gggaaaaaat cccttgagaa
    10861 tgaatacatg tatttagtaa aaaaatattt tgactgcttc gatggtgctt tttccagttt
    10921 gttttgcgat aagtttaggt aaaatctgtt gtaaccattg ttggtcagat acctgatcga
    10981 agaagtagcc gattgttgtt aaaatgagtg tatctgttgt atgttcaact aaacgtacag
    11041 attcaaaagg acttaaccca gcaacatagt tcaaaatatt ttcatctgtt tgttcaaaag
    11101 atcctaaata gttattggta ttccgatcgt aagaatcaac gataggaata gcatttgttc
    11161 ttagcattgc aatctctcct tgattagaaa tactcagtta tcatttttta ccgatagatt
    11221 tagaagcaag aactcttaat ttatgcgttg ttggtaaatt gtcagaccgt tcttcaccta
    11281 agatttcata tagagttatt ggtttcattg ttcttgctcc ttttattttt gtaacgttga
    11341 ctaagaggga aataccctct tagtaataac tgctttcata aaccggttga ttatcatagc
    11401 ggtaaaatgt atcccaactg cgattaccgt ataattcatt gggatataag gctggattaa
    11461 ttcgttttct aacaatgctg tctttggttc gtgcaagcgg ataatcgata aattcatttg
    11521 gtattggcat agtttctcca ctcatagaag tatagttttt tacagtttgc tttttgatgg
    11581 gtcgaaacca tgctgttttt ttggttaatt taataatttg ccaaaaagta acgttggttt
    11641 gttcatagcc ccaactacta taaaaaatgt ctcctacttt gtatggtgta tttgctttca
    11701 tgatctattc ctccaataat atttgatttg ccttatttga tacttagccg aatcaaccaa
    11761 ccattttcgg cagcaagttg tctccgaggc gggtgacctt ttgggagatt tcaatttctt
    11821 tttgtttcca ttcacctcac ttttttgttt tggttggtca ttttcgtata gctaagcgtt
    11881 cgtcggcgtg cttttaggtc acaacgtgtg gtaagagaaa acaagggaat gctgtaggaa
    11941 aaagtttttt atgaaatgat caaaaaagtt tttccgcccc ttgttttgtc ctaccattcg
    12001 ttgtaaaagc actactgccg atgatcgctt agattgggta tacgaaagcg accaacgaaa
    12061 aaagtatggg aataaaaaga aatcgcactg aaatctccca aaaggtcaag atggttttaa
    12121 taagaaattc cttttaatac atttgttatt ttgataatgt ggtggtataa aatagatcaa
    12181 atagttaaaa gaggtgtttg tatgaagaaa aaaggcattc cttattctcc gaaacctaga
    12241 aatgcttttg aaagggggtt atttaaatat tttgaaggcg aaagagatca ggaagaaaaa
    12301 gagaagaatc aaaaaaagaa gtctagtcaa gaaaaagaaa atatagaaaa atagtaggtg
    12361 aaaaaataga gaagtatgaa aaaaagttta atagtattga ttgttggatt aagtatattt
    12421 ggaagtgttt tatttattgg aaactcgttg ttttctaaca aagatgttac ggaacaatcc
    12481 cctgctagca caacggaaga ggtatctcca gagctattat tagagacgga tgttcttgat
    12541 acaaagaaac ctgagacaat tccttcggaa aacgagctct atcaaggaga tctttcattt
    12601 gaatatgcgg atccggaaaa gccgtatgta ctaacgattc ggtttataga taaagcgaat
    12661 catgaatatg tagggcctga taaaaagcca ttgaaaagag agaaagaatt gattctagga
    12721 aaagctaaag gtgtcgtaca cgtagttgta aaagccaata gatcgatgtt aacccatatt
    12781 cagaagttaa aagatatcca agtgtccatg acattaaatg agagaaatga gaaaacggaa
    12841 tgacggaaat cagacatgtt ttgggaatat ctgttctact tttatcggtt tatttatttt
    12901 gttccatctt tatagttgct tgatcatatt acaaaaatga aaggtcattt ttttcttccc
    12961 tgttatttat catcattaaa aatgatgata ttatttcttt aaacacctat ttaaatttgt
    13021 ttctacaatt ttcagtatga taatgatcgt tattttaatt aggtgtaaat gaagaaagga
    13081 agaaaaatat gttgaaaaaa gtgttacgat ttggggtatg tataagtata tggttggtaa
    13141 catcttccac ttttgtgcca agtatgattg cagtggccga ttcggtggcg atacaagaaa
    13201 cgatcgcatc tgatagcgag ggggaagaga agcttacaga acgctcggac gatgcgtcag
    13261 atggacaaac tgaaaaggtt gaagtacaga aaacagaaac tactcaaacg acggtatcga
    13321 gcagttcaga tgaatcaagt gatcttaccc agtccagcga agaaactgcg ccagaagaag
    13381 tcgatgagtc taccgaagag tcttcggatc ctcaggaaca aacgatttct catgaagaag
    13441 aaacgaagga agcagttgat tcatcaacga ttgattttga aggaacacga tcttctgaat
    13501 cattcggtaa acatacctct ccaagtattg ataaacctaa cgaaaaaata gccgaaccag
    13561 tctcttcaaa tgaaggagca gttgtttcac ggcgaagccg ccgagatctt tctgcggttt
    13621 cttcaaatca cccagaagag gaaccggtgg tcgcttttga tgaaaaagcc tttgatgccg
    13681 caatcgatca atacattgat catgcaacag aagaagaatt agggttagtc ataaattcaa
    13741 gcaatgaaaa agaattggcc gatgctttag aatatctctt gttgaatcaa ttggatgagt
    13801 cctttggtgt agaagaactc gatgaactaa agaagttcct cacggcagat gagattgaac
    13861 gattggaaaa tgaatcgtcg ttagagacat ttgaacaact gcttacgcaa tactataatg
    13921 atcgagaaca gaaattggaa gaaggagcag catttagtga cttctttcta gcaagtaccg
    13981 atgaggaaat cgatcggatg ttagaggtaa aagatgaaca agcattggaa caagtgattt
    14041 ctgaaatcag tgcttctcgg aatagtcaaa caagtggaaa gcgaaacaag cgcttcttag
    14101 tcattccatt gcttgtcaaa ggagcgatgt tggtaatcgg ggcaggggta gctgcttatt
    14161 caagccatca gttctataag acgatggaag cacaacgtgc ggaaaagaaa cgaatggtcg
    14221 aacgctggcg ttaccatgaa caacaagcac aaaagcggca tcaagccgca caacaagccc
    14281 gcgccaaagc cgttgcccgt gccaaattac aagcagcagc ccgtgcaaaa gcgcaagcca
    14341 cacaacgagc tcgtgcccaa gccgcagcaa aagcgagaaa acaagcacaa aattgggcta
    14401 aacaacaagc cgccgctcga gctcgtgcac aggcggccgc aagtgcacga agaaagtcaa
    14461 atgcgtccta tgttcctccg gtaactcgtc cgaaaccagt aatcaaagcc caacccaaag
    14521 tacctgcaaa accagtagcc aaaccagtaa cgaaaccaac ttctccagcg aaaccgaagc
    14581 caacgacgac ccccaaaaat acgatgcatc aagtacgtgc aggagaatct gtttggtcta
    14641 tttcgcataa gtatggcatc agtatgaatg acttcatcaa atggaacaaa atcaaaaata
    14701 atctgatcca tcctggccag caagtcatcg tcaaacaacc agcaagtaca tcaaagccag
    14761 tgtccaaacc tgcgacaaaa tcaagtacgc cagccactta caaagtaaaa gcaggggatt
    14821 cggtttgggg gatctgtgag aagtatgggt tatccgtttc aaaatttgtc caatggaata
    14881 agatcaaaaa taataccatt catccaggac aagtgatgca tttacaagaa ccgaaaccgg
    14941 catcaaaacc agcaccaaaa acttctccta cgactaatac gacgtatacg gtaaaagcag
    15001 gagattcggt ctggttgatc gctaatatgc atgggatcag tatgaatgat ctggtgaagt
    15061 ggaataagat caagaataat acgatccatc cgggccaaaa gttgacagtc aaacagcctg
    15121 tttcatcagg gaaaacaacg acaaaagtac ccgcctctac aaatccagtc acccacaaag
    15181 tctcttatgg tgaatcttta tggctgatta gtagtaaata tggtgtgacc gtcgatgaat
    15241 tacgcaaaca gaatggcatc aaaggtgatt tgattcaccc cggccaagta ttagtcgtca
    15301 aaaaaggtat gaccacgagt cattcaactc ctgcaggaaa aagcggaacc agctataccg
    15361 taaaagcagg ggattctgtt tggttgatcg ccaatcgata cgacgtgagc atggatgatc
    15421 tagtgaaatg gaacaagatc aaaaattata cgatccatcc gggtcaagtc ttaacgatcc
    15481 aaacaattgt ttctacacca gcaaaacctg cgattacgac aacaccaaaa gtagaatcca
    15541 aaccagcgat taccacgaca ccaaaagtgg aatccaaacc tggagtgact accacaccaa
    15601 aagtggacga gaaaccagta attacaacat taccgaaagt aaaagaacaa cctgtggtca
    15661 caaccgttcc taagactgaa tcagaagtat tagttgagaa agccagtggg tctacaggta
    15721 cagtctggga tgatattaaa ggtacacaac ctccaagaga aggaactact attcctaaat
    15781 cgtttgaaat aattgttaat ggggaaaagt tgtgggtaaa tccaaatgga accaagcaca
    15841 tggtagaata ttcaactcga aatctatctc atggacaaaa acttaccgaa caacaattgt
    15901 taaggagttt tcaaggtgct gtagaacaag ctacttctac agggataaaa tttgaaacta
    15961 aaataataat agataattgg gaattaatat ttagtccagc tagagaagca ggacaattac
    16021 cagttattaa acatgctgta tatctaccat aactatgaaa ggagcaaatt atgaaaatta
    16081 aaagttatga ggataaatta gtcaaagatg atatagaagt tgactattat gtcccaatca
    16141 cagtatcatt tccagaaaat gatgataagt ataacctagg agaattttat tattatagat
    16201 tcgttaatga atatgaatca tttgttgaga ttaaaatcaa ttctgttaca cagaaaattg
    16261 tagaagtagt attcacatcc atcaatgata ttgaagattc caatttattt attggagagt
    16321 atgcagaaaa aaatccagtg atccaaacag atatttttga tgaaaattcg attataacta
    16381 aagaatctgg gtttaaaata tctagagaac acaaaaaatt atgttttaaa ttagataaag
    16441 aaaagatgga ttctgttgta aagatgtcta atcatgtatc tttatttcta aatgaagaca
    16501 gtgagattat tggtttagag ttttctagct tttcagataa tgaatgggca gaactcaatg
    16561 aaagtataaa atctaccact tgatttaatt ttaaatgaga agaagatagg attttcaaca
    16621 gctattttgc tagattctga ggatgaaaca aaagaatttt gaaagaacaa attcaaatgc
    16681 taaaataaac ggtgggcatg ttatgctgaa aaggttcgag ggataatcca aggtactagg
    16741 tattttgtga gttcctcggg cactatcaaa agcacatgcc caataaagaa agtcaatagc
    16801 aatattagga gagactaatg atctattgac tttctttata gtgttttacg gatcagaaga
    16861 atcatttttc tcattgcctt ccgctccttt tagaaattgt tttataacaa gtaccttcac
    16921 aacttctatt tagtcatttg tcatattaat tttctctttt ccagattcaa aaatagtgtt
    16981 catatttact attagtgacc tttgcttctt cagttgaaaa ttttatatcc actttagagg
    17041 catgtaaaag gttaatttga gaatttccag aagataatct actataaaac caacgtccaa
    17101 accagtggca aaaccaagta cgccagctac gtacaaagta aaagcaggag actcagtttg
    17161 ggggatttgt gagaagtatg ggttatccat ttcaaaattt gtccaatgga ataagatcaa
    17221 gaataatacg atccatcctg gccaaaagtt gacagtcaaa cagcctgttt catcagggaa
    17281 accaacgaca aaagtacccg cttctacaaa tccagtcacc cacaaagtct cttatggtga
    17341 atctttatgg ctgattagta gtaaatatgg tgtgaccgtc gatgaattac gcaaacagaa
    17401 tggcatcaaa ggtgatttga ttcaccccgg ccaagtatta gtcgtcaaaa aaggtatgac
    17461 cacgagtcat tcaactcctg taggaaaaag cggaaccagc tataccgtaa aagcagggga
    17521 ttctgtttgg ttgatcgcta atcgatacgg cgtgagcatg gatgatctag tgaaatggaa
    17581 caagatcaaa aattatacga tccatccggg tcaagtctta acgattcaaa caattgtttc
    17641 tacaccagca aaacctgcga tcacgacaac accaaaagta aaagcaaaac cggcgattac
    17701 cacgacacca aaagcggaat caaaatctgg agtgactacc acaccaaaag tggacgagaa
    17761 accagtaatt acaacaatac cgaaagtaaa agaacaacct gtggtcacaa ccgttcctaa
    17821 gactgaatca gaagtattgg ttgagaaagc cagtggggat ggaagtagat tggatattaa
    17881 tattaaaaat tttgaaatca agaataaaca tttgaatagt tcaactgcta aacgggctag
    17941 aaagtttaat gtttcttcag ccgaagaagc taataaaata gttcaagacg cattaaaaaa
    18001 tggaaaactt gtagaagcta taccaaatgg agtagggagc caaggacaaa attctttttc
    18061 tagtattatt gatacaggga aagttattgg aaccaaaggg gaaacacata taaaaatagt
    18121 ttatgatgaa ttaaaaaatg tgtggactac ctatcctgtc ccaaaacctt aaataggagg
    18181 taagcaaagt gattgataaa caaataacga atattttgca atcgtataaa aaacaacaaa
    18241 tatttaaaat agaggacttt ttactttcag aaattgatga agataattta caagaaacaa
    18301 tagattttgt agtttctgat gatgttagta agaaaattaa ctttagtgat gaattatatg
    18361 atgggaacga gtacgaaggt gtatttttag aaggtaatca atatttacta tctagctcag
    18421 aaggaaaagt aatgataatt gatatgttaa gtgaggctca tggtgttaat ataaaagata
    18481 ctcgagttca atttgatgaa gaaaaattta tcaaactaat cacgaacaaa aaagaaattc
    18541 ttaattggat taaaaattat aaagtggata aataaaataa aaaaggcact ttactattcg
    18601 attggcgtcg aatagcaaag ccttgaatag taagcataca ctcactaatc aagttgctaa
    18661 taaaaagtta tctatgtata gaatagtata agctgaagtt gaaaaagaaa cgatttagtt
    18721 gtatcgtttc tttttctatt ttatcgctta attttaatag ttaattattt gaatgatata
    18781 taaattttaa tcaaagaaag acaatttatt gttgaaatag ttgttgaagc tttcgaggcg
    18841 ttcttgaggt acagttgaaa gctttatatc cactttagag gtatacaaaa gtttaatatg
    18901 agaattctca gaagataatc tactataaaa cagtagataa gtcagcgccc aaaactaacc
    18961 attcgttgta aaagcaccgt cgtcgatgat cgcttagatt ggctatacga aagtgagcaa
    19021 caaaaaaagt ttgggaataa aaagaaagcg tactgtaatc ttccaaaagg ttaagatgat
    19081 tttgataaaa aaatttaata tatttgttat ttttataatg tgatgatata aaatggatcg
    19141 aacagttgaa tgaggtgttt atatgaaaaa aagtcactcc ttatcgtcca aaacctaaaa
    19201 acgtttttga aagaggaagc ataaatattt tgaaggagaa aaggggcaag agttaaaaga
    19261 gaagaatcaa aaaagaagtc caagaaagaa aaaatgtgag tatatttttt agaaagaaag
    19321 gaattgttgc gaaactagac cgtaaagatt tataagtaat cagtaaccca tactttttat
    19381 atttaaagag gttatttttc tgtaaatcgt tgtaaaaaat atctgagttg tagtattttc
    19441 ttcacaaaca ttcatataat aatagtttta tttaataaat acattgtttt taaactaatt
    19501 tctatatgtg ttttgttgaa ctaactcttg acataaaatt taaaaggatt tatagttgtt
    19561 accgtagtag ctactaaaag ataaagtgag gattaatcaa tggaaacgat tattcaaatc
    19621 atgaaaaaat atgatttttc agagatggaa acaagagtgt ataccacact attggaaaaa
    19681 ggcaatctta caggatatga agtaagtaaa gtctcaggtg tgccacgctc gaaagtatat
    19741 aacattttgg aaaaactatt aaaaaagaat ttgattgtcg tcaataaatc agaacctaaa
    19801 ctttatcatg ccatctcggc aaatgagttt ttagagaaat tagaaaaaag tgttaaaaat
    19861 gatctctctt ttcttactca aaatctaggg atgatcaaag aaaaagatga agaagaaatg
    19921 ctgtggaaag ttgatggcat cgagtatgtt ctggataaag cagagcattt ggtgaaaaat
    19981 gcaaaagaaa gtttgctcat ccaagtttgg catgagaacc tcacggattc actgctaaag
    20041 acattgcagc aggctgaaaa aagagtcgat aaatttgtac tgattttatt cagttctagc
    20101 catgaatatg atcttccctt agaaaagtat tacattcatg gttttgaaac agacaaactc
    20161 gctgactttg gggcaagatg gataaacatc gtcgccgatg agcaagaagt cgtgtttggc
    20221 accattaacg aagaactgca atcaaccgat gtcacttgga caaaaaacca cgccatggtc
    20281 aatctagcaa aagaatatgt caaacatgat gcatatacac taaaagtgat tgcagaatct
    20341 tctgaagaac ttaaagcaaa atatggtgag gactttgagg gaatcagaaa gatttactag
    20401 taggaggaaa tttttatgat tcggaatatt ttgctggcac taattgtcgc aatcaatcta
    20461 tattttatta tttactttct aagagacctt ttcaaaaaca aacaaaattt caaagaagaa
    20521 ccaggggata tgcgtctgtt gcccttcacg tcatttatca ccttctttct ttcaacattt
    20581 ggcgtttccg actttgctat cggaaccgtc ctttatccaa agttgaaatg ggtcagcatg
    20641 aaaaaactac ccggaacgtt gaatacccaa tgtgtcgtac cggtagccgt catggcattg
    20701 tcttatatca ctgccatcaa cgtaggggtc aagacactag ctgtttgtat tatctgccaa
    20761 attatcggtg catatttagg accaagattt gtcgtgaaat taccagaaaa aacgatcaaa
    20821 ctatttgtcg gcataggatt ggtcattgct gcattcttaa tttttatggg acaaatgaat
    20881 tggattccct caaacggaac agccagtgaa ttgtatggcg gaaaattaat cttggcagga
    20941 tttttactct ttgtctatgg cgcattgaac aatattggca ttggttctta tgcgctaacg
    21001 atggtaactg tctacttgct aggcttgaat ccagttgcag cctttcctat tatgatgggg
    21061 gcttgtacat tctcagtacc gatcggcagt gtccaattca ttaaatttga tgaatacagc
    21121 agaaaaatca cacttttcac ttcaaccttc ggtgtattag gggtattggt cgctgtattc
    21181 ctagtcaaat ctttagatac ctatgtcttg aaatggatcg taattttggt cttactatac
    21241 agtgcataca caatgttggg cagtcaatta aaaaaagttt cagcagctaa ttaaggagcg
    21301 attcaaatgt tatttcttaa aaaagaagat attatcaaaa gtttctcaat gagagaagcc
    21361 atcgatgcag acaaaaaagc attgtcattg tattcagcag gaaaggcaag tgtgcctctt
    21421 cgcaccaata tcgatgtgcc aaaaagcaac ggacaaagct tatatatgcc agcttatgta
    21481 gaaggtggcg aaggtgcgtt aggtgtcaaa atcgtttccg tgtatcctga aaacctcaag
    21541 aaaaacttac caagtgtacc agccacgatg atcgtccttg atccagaaac gggtatggta
    21601 tccgcttgtt tggatggtac ctatttgaca caattaagaa ccggcgctgt tcaaggtgca
    21661 gcaacagaac ttcttgcaag agaagatgct aaaatcggcg cactgatcgg aaccggcgga
    21721 caagcacagt cgcaattaga agcgatgttg accgttcgta aattagaaga agttcggatt
    21781 tttgatattg attttgaccg tgccagccga tttgctgaag aaatgatgca acagttttct
    21841 gtaacgatgc gcccaacaaa aaccagtcaa gaatgcgttg aaggagcaga tatcattaca
    21901 agtgtgacca cttcaaaacg tgcgacattc tctgctgagt gggtcaaaaa aggtgcgcac
    21961 atcaacggag tcggtgctta cacaccggaa atgtgtgaaa ttccacgaga aataatcaaa
    22021 gccgcagatg ttgttatttt tgataccatg gacggtgttc taaaagaagc tggggacttc
    22081 atttcaccgc tgcaagatgg gtatattcaa agagacagtt atcatgggga actaggccaa
    22141 ctgatcaatg aagaattgat cggtcggaca agtggagaac aaatcacaat tttcaaaaca
    22201 gttggttcgg ctgtattaga tgtggtagtt gcgacagaaa tcgttaataa agctaaagaa
    22261 aataatttgg gaaaattgat ttattaaata aaaagaccgg aagtaaacct ttaattagta
    22321 catttataaa aagagaacaa aaaagactgt aatcaaaatg cgattacagc ttttttttgt
    22381 tttatttggg aggagataga tcgtgtttat gactgtatcg gatcatttaa aggtacttgg
    22441 ttttatccct ttatctagta gagggaagta tcaattgtat ttgttagatt taccacccta
    22501 gcttttcact ggtgattgaa ggaacatacg ataaaaaaag tggtaagtat ttttatgatt
    22561 tttattctat gaaacttgat cctaaaacaa agaaaagtac gcagcaccgg atttattgta
    22621 cgcatgttcc tgtaaaagta atgtatcgtc gtgtgagaaa ttatttatac ttcttacgta
    22681 aaaaacagca atcaaggaac agaaaaaatg cataatgagg aatatcaagt gaaattttta
    22741 tcagttttgc tctgtggtat tgtgtattgt cattagttca atgagtatta acagggagga
    22801 aaaagcaaat gaattttttt caaaatgtgt ttaccgattt tgttggggat tttaagtatt
    22861 tgattatgtt ggcgatgctt ggtggtgcgg catatattgc ctttgaacgg aaagcaagca
    22921 aagccattcc attgattctt gtgctagcag tagctgtttg gttagttgga gatacgtctg
    22981 gcgtattcaa ttggattttg gatcgtatgc ggtcatgggg gcgataaaat gagtgaaata
    23041 cgcaattgga caaagatttg gtatatagag cgagtgtttt ataaattgtg ggatggggtc
    23101 gcgttacctc gtcctgtaac acaaacattt gcgatatggt ttgggattgg cttttttggg
    23161 gggatttttc gaatttttcc atttgttatg gaacatacga ttactcgaca atttttttgt
    23221 ccgtggttat ttgctttttt aatgacacga aaacaatttc aaggaaggaa gccttataat
    23281 tatttggctt cttttctttt atttcagtgt cgttcaaaag aatcctttca tggccaatgg
    23341 gtaaagccaa tagaaaaaaa agaaatcaaa cgaggaattc gttgtgtagt acgttatgga
    23401 ggtgaaaagg atgcgactac caaaactagt gcctaagatt cctttttatt atttagaaga
    23461 caatttagtt tttggagaag aagatcgtgt gtacgcttat tatgaattcc caatgtattc
    23521 atatagcttc gtgggagaag atcaggcgta tcaactccaa caagcaatca tgcgtctgat
    23581 tcgtcaaagt cattcttcgc atgttcggtt ctttttttgt acaaacgaag aaaaaattga
    23641 aaaaacgatt aaatcctcaa aagaattggt gcgttctaaa ggggaattaa aaacgattgc
    23701 ctaccaacat ttagaaggtg ttcagcacat tttagaagag ctacatggaa aatatattca
    23761 aaatgtttgc tggtatgttg ggattgagct ggtattagaa gaaattgctc ccaaagaagc
    23821 tcattggtta aaagaatttc gtattgccgc aaaagatttt tttcaccgat ccaatgcccg
    23881 tttgtttgga gactttgaaa ccatcccaaa tgaaaaaatt caacgatata agcgattgga
    23941 gaatttattg tataaccgga ttagtaaata ctttcggtta cgaaaaacaa caccagaaga
    24001 catggtgttt ttagtggaac atttagaagg aaaaaaagaa caatccttag atgaagtgat
    24061 gtatcgacca aatagcttta aagaagaaac gaatacgtat acgtatcact atgatgtatt
    24121 gaatttggcc agtgcaggaa tcacagaaaa gaaaaattat ctaattttag aacaagggac
    24181 agaaaaagaa tatatcacgt atttatctct ttcacgtatg acccgtgatt tggtatttcc
    24241 atttcaatca gagatttatt attttttaca atcggaattg gattttccaa tcgattcttg
    24301 gttagatgtg aatcttttag ataatcgttt ggccttggcg aaagtacgtg gcaaaaagag
    24361 tgatttatct gatatttatg aaagtggtat gtcggttgga aaagatgtag gaaacaatgt
    24421 acgcgaagct taccaatcag ccaatgagtt ggaacaaaaa ttagaagata cgcgagaaga
    24481 tttgtatgta ttatcactaa acgttcgcgt gtcagggaag acctatgatg aaatgttaaa
    24541 acgtgtgagt gatgttcgca atttttttga tgtctattct atgtatttag aagtaccgtg
    24601 caatgtacag ctgcttttac attttggaag ttatccagca ggaaggcgag tgattgagga
    24661 ttatcgtcaa tatgtaggcg cagaatttat tgctagtctt ggcattggtg cgacacaaca
    24721 actaggagat ggctgtggta ttccgattgg atttaatgca gaaacaggaa tcccagtgtt
    24781 tattaaacca tggttagcgg cacaaggaat aaaaggaacg gttaccaata ctcttgccaa
    24841 agcattaatt ggttcgctag gtggtgggaa atcattaact gagaatctct tgttattttg
    24901 gtcggtgttg tttggcgcct tggctttttg tatcgatcca aaatcggaac gttcaaattg
    24961 gtccgaagat ttgccatatt ttgcccccta cttaaaaaca gttaatatta ccagtgagaa
    25021 agaaaatatt ggtttacttg atccatttca attgatgaga agaaaaaaag atcaagaaag
    25081 tttagcattg gatgtgctca cctatatcac gggtgtaagt attcgggacg aagaccggtt
    25141 tcctttgtta caacgggcag ttaaaactgt ttctgatttt gagggaacaa aaggattact
    25201 tctagtaatt caggaattat atgcacaaga agcagcgacc gcacaacgcc tggcaaagca
    25261 tattgaaagc ttcaaagaac tatctattgc aggcctatta tttggagatg gcacgaacca
    25321 acaagggtta aatttggatg ccaaatgtaa tctcgcactg gttcaggatt taacgttacc
    25381 agatagtgaa actgtacctg aggactataa ctcttctgaa attttaagta ttgcgattat
    25441 gatgagtttg gctacgtatg cgctagattt tattaaacaa aatcgaaaaa tttataaagc
    25501 ggttggctta gatgaaagtt gggcgtggtt gaatgttgcg caaggaaaaa ttttaggaga
    25561 taaattggtt cgtgaaggaa gatctcgcaa tgcagggatt gatttttcaa cacaaaacac
    25621 agatgattta ggtgatgaaa agatgagaag taaaattggg ttgaaattca tttttcgttc
    25681 gaatgatcgc gaagaaatta ccaaagcatt aagcttttgt ggaatatctg tcacagaaga
    25741 aaatatccag cgtgtaaaaa atctagaaaa cggtgaatgt ctgttttgtg acatccatgg
    25801 taatattggc attttgtatg tgtattattg gtttgaagat ttattccatg catttgatac
    25861 acgaccgcca atggaagaaa cctacgaaga ggaagaatat aaagacgaga tattagaaaa
    25921 actggttgaa gaaattgagg tgaattagat gaaacagtgg tattcaaagg tttcattttt
    25981 aattactcgc cggaaactgg ttttcataag tctagtcata atgatgggtg tttttttctt
    26041 tcacccatca ttagtagaag cagctggttg gataaaagaa accctaggcg gcaaaaatgc
    26101 cgtatatgat tttgaaacat atcctttaga taattataat ttagattttt ttgtggatac
    26161 gtcgtggaat tggttgccgt ggaaatgggg tgaaggaatt tctaatacag ttatttatgg
    26221 gatatttgcc gttaccaata ttttatggat gttaaatgtc tacctgtgtt actttttagg
    26281 gtttcttgtc caagaagcct ttgaattaga ttttctttca gagttgattg gttcgttaag
    26341 tcatacaatt cagaatattg ctggaatgaa ccgtacaggg acattgagtc atggattagt
    26401 ccctttcttt ggtggattgt taattacttt agcaggttgt tcagtagttt atcaaggaat
    26461 agtgaaacaa caccctacgc aagctattca acaagcggtg acatttttgt ttacttttat
    26521 ttgttgcggc gttttcttta tgaatacaaa cacatattta gagaaagcta atggggtaca
    26581 aaaagaaatc aatagtgaaa tgttaaccat tgccaaaaat ctgttacctg aacaaaaaga
    26641 aaaaccagat gcaattaagg ccattcgtga gaatttattt gccattcaaa ttaagcaacc
    26701 ctggctagtg atgcaatttg gggatagtga tataaaaacg gttggtgaag aacgtataat
    26761 caatttatta aaagaatcac cttatgatga aggagaacag cgaaataagc ttgttgaaga
    26821 agaagtaacc aaacaaaaaa atggccatct ttcggtacaa aaagtgtatt tgcgttttgg
    26881 tatggtattt ttaacgctca tcgtcaacat tgtcattagt atgagtgttt tggtattaat
    26941 cgttatctta attgcgtcgc aagtattatt cttgttattt ataggattct tacctgtagc
    27001 gatgattttc tcgttatttc caaattcagg atcgttatta ggtaatgcct tacagaaagt
    27061 ctttcaatta ttgtttacaa aaatgggtat tttactcatt ttaaccatta ctttttctat
    27121 tagtcatgag ttaaaccact tatccaagga caaaggaatg atttggacca gtttcttaca
    27181 ggtgacgtta tggttatctg tctcgacacg tgtcaatgaa ttattaggtt ggatgaaaat
    27241 tggtggcgta caaacacgag ctggggatcg aactggacgt ttcttacgtg gcatgatgtt
    27301 aggtacaatg ggtcaaaaaa tgatacgagg aattggtgaa aattttgttg ggggtactgc
    27361 cggaggtgta gctggccaaa tgatttccaa atctatgagt ggtcaacgaa gtatagcttc
    27421 tacacctctt atagagcgag taggaaaaaa agtttcagct atgacagaat taccggcaac
    27481 gattgaaagt agggcagaac aatggaagcg gacaattcag tatgtcccaa ccaatgccca
    27541 atacaaagca caaaaaatga aatacgatta tttctctggg cgaatgaatg agtcggaacg
    27601 acaaacacga gcgcgtaacc ttgcgaatga gcgacagaag aatttttatg aagcacgaaa
    27661 agatgcattg caattagagc aacaagagag aaaacaacga gcgatgcgtt caatggcgca
    27721 tcaaacagga aaaacacaag tgacttctgg taaattacaa acacggaaaa gtgcaatgat
    27781 tggtcgaaca gaacaatttc ctacgataga aaaaagaagt aacatttcaa atatagctaa
    27841 aaataagaaa ttgtcgaagc aggaacatcc gattcatgaa cgaagtacga atcgaaagat
    27901 tgaaactccg gttcgttgga cttcgacttc tcgtcaaaac gcgagaaaag gtagaactaa
    27961 aaaagaataa ggaggagggc tatgtttcct cggaagaaaa aactgtctat tctctctgaa
    28021 caagaaacaa gactaaaagg aaagaaagac aagaaaaaag aaagctataa gggagcgcga
    28081 aaaaggcgct tccttttttt tgtaggctgg agctttttgg tttttagtgt ttgttttgga
    28141 gtttataata atttaacttc tcaagatacg catacaatcc atgaaacaaa agtcattgat
    28201 aaacaattaa aagatatgac tggaatagaa agttatgtga aaaattttgc atttttgtat
    28261 tttacagtga gtcttgaaag cgaccaacaa ataaatcgat caaaagcagt agaaagttat
    28321 ttagctgatg ggctgcaaat ggataatgaa atagataaag acatagaaac gaatgtaaaa
    28381 gttaaaaatg tctcgatttg ggcaatagag gaacatgaat caaaaaaaca tacatttgtg
    28441 gttatgtttc atgtcttatt agagatagaa aaagaattca aagagcgtgt gtataaggtg
    28501 gaggtatatc gaaacgaatt atcatatgcc atagtgaaat tgcctattgt agcgagtaat
    28561 gttaaaaaag caacgattaa agtagacact cggttcgaaa caacgagcat ttctcgaaaa
    28621 gaacaggaag aattagagaa attcttatat accttctttc gtatttatcc taaagcaaac
    28681 gcagaagaat taaaatatta tgggacaact cttttaccaa ttcaacagcc tttagccttt
    28741 gaagaactat cgaatttgca agtcgcaaaa aaagagggta gatatgagat tcattgtaat
    28801 attttgtatc aagatcaaga aacgcacctt tggtttacca tgtactatga aatgtctatg
    28861 aaacaattag agaatgggaa ctttcgaatt gaggcgattc attagtgaaa aagatttttt
    28921 tatttagtgg catctgtatg atgagttgtc tgtttttatt atttgcgata attagcatgt
    28981 ctagtggtga atcgaagcac atggattcag cagttggtgt tactcatacg ggagaatata
    29041 tcgaaacctt acctattttt tcagagatca aagggcgtgg tccgataaca gatgaacatg
    29101 cccaagcagc agttggtgca gctgtaaagt atcagttatt accgagtgtg attctttctc
    29161 aattaggata tgaatcagct tatgggcagt cacaatctgg aagaaacgat acgaactttt
    29221 ttgggattac gtggtttcct ggttgtccct atccacaagg ttctgcacgt gggattggtg
    29281 gttctgaagg tggtttctat atgaagtttc cgaacctgaa tgcttgttat gactattatg
    29341 gatttatggt ggcgagtcaa agcaacttta atcaatgtgt gggcaataaa gatcctggaa
    29401 gttgtttatt gattctaggt cgtggaggtt atgcggcggc aggtatcacc gaaggcagtt
    29461 cgtattatca aggcgcaata agtatcataa agtcctataa cttaacggaa tatgatgcct
    29521 ttgcgatcaa gcattggaat agcctaccaa tcaaaaaaac ttcgcttatt gcaggaaaaa
    29581 gtaaaggcaa tgcgaaggtt ttggatcgga tcattggacg acccgtaaat aatggggaat
    29641 gttatggtgg tacggcatgg tatgtatctc aactaggtgg cccacagtta atgggttctg
    29701 gacacatgtt tgcgatgtta ataggggaag attataactg ggcaacctat ggttggcaag
    29761 tgatcatgaa tccaaagccc agtgacttac aagcaggaga tgtggtcaat tggcaagcag
    29821 gtggtgcatt gtctcctgga atctatggcc acacgggtat cataacagat gtctcaaata
    29881 gtggacaaag tttctccacc gtagaacaga acgccgagca ggggcgaatt atggcacggt
    29941 atcaacgcgg ctataaccaa gcgaaaattc gaagtctggt tcggaaagtg aaataaaaga
    30001 attctttcga tgaaaatttt tagtagaaaa gggagaagga tcgattgtga aaaagtatta
    30061 ttttttcttt ctaagttgtt tttgtttgtt tggacttact agttgtgggt ggattttttc
    30121 tgaagaaaaa acagaagttt ccttaatatc aaaagaaaag atgatacaag cagaaagttc
    30181 aagtaaagaa agcaaaagaa atcaggaaga caaaacagaa tgcaatattt ctgaagaaat
    30241 ccaatatttg ttaaagaatt ttggaagaaa atgggtgaat tacacggata tatacgaacg
    30301 aaatcaatct gtaaaaaact atttaaccga tcgttgtata aaagaaaatg ggattgac
//
LOCUS       DAZKPE010000031        29205 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000031 DAZKPE010000000
VERSION     DAZKPE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.031"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(206..658)
                     /locus_tag="ACG930_001517"
     CDS             complement(206..658)
                     /locus_tag="ACG930_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0518681.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(671..1081)
                     /locus_tag="ACG930_001518"
     CDS             complement(671..1081)
                     /locus_tag="ACG930_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0518682.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1356..1568
                     /locus_tag="ACG930_001519"
     CDS             1356..1568
                     /locus_tag="ACG930_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFQ0518683.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1571..1783
                     /locus_tag="ACG930_001520"
     CDS             1571..1783
                     /locus_tag="ACG930_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518684.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1923..2078
                     /locus_tag="ACG930_001521"
     CDS             1923..2078
                     /locus_tag="ACG930_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518685.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2075..2299)
                     /locus_tag="ACG930_001522"
     CDS             complement(2075..2299)
                     /locus_tag="ACG930_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFQ0518686.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2377..2565
                     /locus_tag="ACG930_001523"
     CDS             2377..2565
                     /locus_tag="ACG930_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518687.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2704..2832
                     /locus_tag="ACG930_001524"
     CDS             2704..2832
                     /locus_tag="ACG930_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518688.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            2891..3226
                     /locus_tag="ACG930_001525"
     CDS             2891..3226
                     /locus_tag="ACG930_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518689.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3459..4400
                     /locus_tag="ACG930_001526"
     CDS             3459..4400
                     /locus_tag="ACG930_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HFQ0518690.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4402..5292
                     /locus_tag="ACG930_001527"
     CDS             4402..5292
                     /locus_tag="ACG930_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFQ0518691.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5335..6135
                     /locus_tag="ACG930_001528"
     CDS             5335..6135
                     /locus_tag="ACG930_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFQ0518692.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6150..7001
                     /locus_tag="ACG930_001529"
     CDS             6150..7001
                     /locus_tag="ACG930_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0518693.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7202..7663
                     /locus_tag="ACG930_001530"
     CDS             7202..7663
                     /locus_tag="ACG930_001530"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0518694.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7689..8141
                     /locus_tag="ACG930_001531"
     CDS             7689..8141
                     /locus_tag="ACG930_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518695.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8247..8441
                     /locus_tag="ACG930_001532"
     CDS             8247..8441
                     /locus_tag="ACG930_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518696.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8472..8765
                     /locus_tag="ACG930_001533"
     CDS             8472..8765
                     /locus_tag="ACG930_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518697.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8696..9235
                     /locus_tag="ACG930_001534"
     CDS             8696..9235
                     /locus_tag="ACG930_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFQ0518698.1"
                     /translation="MVSEKQREFSSGEIGGHGSYKILILLFYNYPTTMSVIPQLEGEE
                     AIVNILENIDIKQTRKNARRLLKRYRNLERLVGPVKIDFSVMTVTKNLKFTIDSQNEE
                     IIEAISTRDSVIEALTRLSRIHFQVLYYSYCFPNKMSMYQIGEKLGYSDRTIERMKAV
                     ALVEFAEAYKSGELISRTK"
     gene            9310..9777
                     /locus_tag="ACG930_001535"
     CDS             9310..9777
                     /locus_tag="ACG930_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HFQ0518699.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10524..10754
                     /locus_tag="ACG930_001536"
     CDS             10524..10754
                     /locus_tag="ACG930_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518700.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            10913..11746
                     /gene="terS"
                     /locus_tag="ACG930_001537"
     CDS             10913..11746
                     /gene="terS"
                     /locus_tag="ACG930_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFQ0518701.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11739..13154
                     /locus_tag="ACG930_001538"
     CDS             11739..13154
                     /locus_tag="ACG930_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFQ0518702.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13166..14695
                     /locus_tag="ACG930_001539"
     CDS             13166..14695
                     /locus_tag="ACG930_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0518703.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14613..15665
                     /locus_tag="ACG930_001540"
     CDS             14613..15665
                     /locus_tag="ACG930_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFQ0518704.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15667..15984
                     /locus_tag="ACG930_001541"
     CDS             15667..15984
                     /locus_tag="ACG930_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518705.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16111..16734
                     /locus_tag="ACG930_001542"
     CDS             16111..16734
                     /locus_tag="ACG930_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFQ0518706.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16749..17639
                     /locus_tag="ACG930_001543"
     CDS             16749..17639
                     /locus_tag="ACG930_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HFQ0518707.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17662..17877
                     /locus_tag="ACG930_001544"
     CDS             17662..17877
                     /locus_tag="ACG930_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518708.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17889..18230
                     /locus_tag="ACG930_001545"
     CDS             17889..18230
                     /locus_tag="ACG930_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518709.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18230..18601
                     /locus_tag="ACG930_001546"
     CDS             18230..18601
                     /locus_tag="ACG930_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518710.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18594..18989
                     /locus_tag="ACG930_001547"
     CDS             18594..18989
                     /locus_tag="ACG930_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFQ0518711.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            18991..19368
                     /locus_tag="ACG930_001548"
     CDS             18991..19368
                     /locus_tag="ACG930_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFQ0518712.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19369..19977
                     /locus_tag="ACG930_001549"
     CDS             19369..19977
                     /locus_tag="ACG930_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFQ0518713.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            19977..20318
                     /locus_tag="ACG930_001550"
     CDS             19977..20318
                     /locus_tag="ACG930_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518714.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20560..23349
                     /locus_tag="ACG930_001551"
     CDS             20560..23349
                     /locus_tag="ACG930_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFQ0518715.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23339..24079
                     /locus_tag="ACG930_001552"
     CDS             23339..24079
                     /locus_tag="ACG930_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0518716.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24076..26838
                     /locus_tag="ACG930_001553"
     CDS             24076..26838
                     /locus_tag="ACG930_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFQ0518717.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            26851..27759
                     /locus_tag="ACG930_001554"
     CDS             26851..27759
                     /locus_tag="ACG930_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFQ0518718.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            27759..28379
                     /locus_tag="ACG930_001555"
     CDS             27759..28379
                     /locus_tag="ACG930_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518719.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            28383..28832
                     /locus_tag="ACG930_001556"
     CDS             28383..28832
                     /locus_tag="ACG930_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518720.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            28832..>29205
                     /locus_tag="ACG930_001557"
     CDS             28832..>29205
                     /locus_tag="ACG930_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518721.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGS"
BASE COUNT        10477 a         4211 c         6040 g         8477 t
ORIGIN      
        1 ttagtttttc atcatttttt tgttctaatt cataagcttc tttttttatt gtgttagctt
       61 tcgacagttt agtgattcct ataattaata aaataagtcc aatcaataat aacattcaaa
      121 actcctcatt tctttgatat aattattgta gagtttactc agaaatgagg aaagagtcca
      181 tgtgaaagca tgggcttttt tatttttaat gttgtaatac taaatgttca agattatgag
      241 gaagccctaa atattcaata atttggaact gactcatatc agataaatct tgttcatcta
      301 ttgttctagt taacatttca attgcaaaca tattagcttc agcttctata ccataaatca
      361 tacaactaag gttgtttgct ctaaaagctg ctgtgcaaat acctttatgg agtctaacgt
      421 gggctatttc atgccataat acaaatcttt tcatagaagg tgataggttt tgattaatta
      481 atatcacata acatctttta ttgtgtatcg tttgtcctaa tgttttattc cctaaatcag
      541 tttcaattaa atctatatca gaatatttga ttattttata tggattaatc gcatcagatc
      601 caaactctac aaataatttt tctatttctt ctaatatcca gtatttgttt aaatgcatac
      661 caaagcccac ctattgacga tattttttag gagtgaattt tttctttgct ttaactttgg
      721 ttaaggcaag tgcaagttga atggcatcgt ataatttttc cttatcttca tcgtctaaag
      781 gttcaccata ataatttgtt tcagcatctg aattcaagcc ttcaagtaat ttttcagctt
      841 gtaaagcaat atcttgttta tctttttctg ttaaatcata ataatggcgt ttatcagtac
      901 gtcctaaaag ataatcagtt gatacattaa agtaatctgc aactttttgt attttatctc
      961 cagatggagt acttttattc catctagaca tgcttccatt tccgaaattt aactttcttt
     1021 caagttctgc caacgtcatt gaacgttctt ttaataagat ttttatacgg tctaatagca
     1081 taggatatgc attcctttca aaataccgac aaaaaaagta tttttctgca aattatctat
     1141 ttacaaatag agaatttgca gttatactag ttttgtaagc aagatattta cggcatacaa
     1201 agactaaaag caataaacta atagtctccc cagacatcag taagctcgct ttttgtgcgc
     1261 tgtattttgt atgcttacat aatagcatat ttgcagtttt tgtcaaactt attagacaaa
     1321 aatattagaa aatattcgat aagggggtat gaagcatgac tttaaaacag caagtattaa
     1381 ttgctttagt aaagaaaggt tggagtcaaa gagagttagc tcgacgaatg ggtatatcaa
     1441 ttacttattt acgagatatc ttcatcgaaa aaagaaaacc taaggaacgt ttaaaacaaa
     1501 tcgaagaact tttggatatc aagttagaag tagattctaa tgatcagcca tcagaacagg
     1561 aggcgtaaaa atggtacaac gtttgagcaa agcggagttt aaagagaaat ataagtattc
     1621 tgaaagtact tatcaaagaa gaatgaagga atttaaaaaa tcacgtttta gtgaggggta
     1681 taacgcagtt acttccaaag aaataacaat tgatgtcgat ttatatgaac agtttagaac
     1741 atggcgttct aaaaatcgat ttagagttag agctgtttgt taatagctaa aaaatctaaa
     1801 ttcaccactt ctgaaaagag gagttgctgc tctcctttca agtttgccaa agtccacgtt
     1861 ttttcatttt ggcaactcct cttcttggag gtggtgacgg cgagagacga aggagggatg
     1921 acatgaagga agaatcaaaa atagggattt tgaatgagaa caattacaca agattaatta
     1981 ttgaaacaga agaagggaaa aaagtagcag aagttacatt gaccgatgca actcctgctg
     2041 acggttatcg tattcgatta actcctaaat atgattaacc ttttggtggg tgtggatcgt
     2101 ttccgtgact atcacggctt tgaatttttc catctctgcc atgaataaat agctcagatc
     2161 cttgattttt agaaatctct ctagcgattt ttactgcttc tgattttgta ttagtatgtg
     2221 cagtcgcttt agaatttcca gcacctttga cattccaacc accattggaa ttaggtacaa
     2281 catgttgatt ttttcccata gttttcacct ccatttctat agaaatattt tatcaaatag
     2341 aaatggagaa attcaataaa cgaaaggaga agtgatatgg catatacctt gcaacaagaa
     2401 catcaaattc tcggtttgat taaacaacgc aggaaacaat tacaagatga ccgtgcagcg
     2461 cttagaaaag ccgatgagct atcagatagg caagctgaac taattgcttc tgaacttgag
     2521 gatttgagaa tgctagaaat aaaaaatagg gagattagat tatgaagaag acagacacac
     2581 tttttatagg attcattttg gggttattag tgattgtagc gcaccaaagt attatcgggg
     2641 gaagcttgtt cgcagcattg atggttttaa tcaatctgct tgattcaaaa gaaaggagca
     2701 actatggcac gagaagaagc gctaaaaatc ggtaaagtga ttgctgataa tcggtgggga
     2761 aatagccgcc ctattatttt aagcaagcaa catatcgaaa agcaaaaagc atggcaacaa
     2821 ataaaaaagt gactctgcca gccagcaaag agtcacatac aaatttataa aactaggaga
     2881 attatatcac atgaataaga aaattgaaaa tcttatcgaa gaattgaaac gtgaatgcca
     2941 aaagcaaggt gtttctatta tttgtacagc ccaaaaagaa ggggaactta aaagtctcgt
     3001 ttatggtgag acaacagaaa ttttactttg tcttgctatg caagaagaac atttagatga
     3061 aaatctccca ttgtcagcac atattatgcg tagaattgct gtggatgctt acgaacaagc
     3121 gaaaaatgaa gaagaaaatc aaccttcaaa tcatactttt gttattaata acaaggaaga
     3181 tttagctgat gtgatgactc gtattctcaa gggggaattt caatgatgaa tgaaaaaaca
     3241 attgatctac tcattatttt atttttcacg ttagtgattg tagcgaaaag ttatgtaatc
     3301 tttggcttgt tattcgcaat taccatgctt gtgctttgcg tgttagcaag cagaaaagag
     3361 gttaaacatg aacgagttag caaatcttga caactattta actgatcctg attatgctaa
     3421 accaccatat gaagcaccaa ttgatgagga ggatgaagat gagtaaatct accttagaaa
     3481 tgagccatca agaatggctt gaagaccgta agaaaggcat cggaggttcg gatgttggaa
     3541 caattttagg attgaataaa tggaaatctc cttatcaact atggctagaa aaaacaggac
     3601 aagtagtact tgaagaatca ggaagtgagc ccgcttattg gggtaatgtt ttagaagaag
     3661 tggttgctaa agagtttcag gaacgtacag gcaaaaaagt acgcagaaga aaccaagtat
     3721 ttgaacatcc attacatcca tttttaagag caaatattga tcgggaagta gtgggagaaa
     3781 atgccattct ggaatgcaaa acagccaatc aatttctcgg taaagaatgg gaaggcgaag
     3841 aggtaccgct tagctatctc tgtcaagttc aacattacat gaacgttcta aacaaagact
     3901 attgttacat cgctgtctta atcggtggtc aaaaatttat ctggaagcgg attgaacgag
     3961 atcaagagct gatcgataca atcactgaac aattagtaga gttttgggaa acaaacgttc
     4021 ttggaggtat cgagccaatt attgatggta gtcaagcgac agctgatttc ttgaaagaga
     4081 agtatgcaga tgttgaagac gttcaaacga cgttaccaat tcatttcgat gaactagttg
     4141 aacagaaaaa cgaactcaaa cggactaaga aagaaattga atcagctatc cgtcaagtag
     4201 acaacgagat tatcagcgag ctaggtaaac gtgaagccag tatcggtatc actcaaaaaa
     4261 acatcatcag ttggaaattt gtccgtacga gacgtatgaa ctcgaagaaa ctagcagaga
     4321 aatatccaga tgtcgcaaat gatgaagaga tttataacgt tactgaatca agaaggctaa
     4381 ccgaaaggga gatcaaataa tatggcaaca aatgaatcgt taaaaaatca attggcagca
     4441 aagccacaga aacaagttgc accaggtcaa ttaggactta aagctttgat gaatacacca
     4501 acaatgagaa agaagttcga agaggtgctt catgacaatg ctaatgcttt tatgtcgaat
     4561 gttatgactc ttgtatctaa tgacagttat cttgcagata gtgaaccgat gtctatcatg
     4621 agtggtgcgt taactgctgc aacattaaat cttgggctag ataagaattt aggttatgca
     4681 tatttagttc cattcaatag taaaaacaag caaacaggaa aatgggaaaa gaaagctcaa
     4741 ttcatgcttg gctataaagg atatatccaa ttagcccaac gatcaggtaa atacaaagca
     4801 ttaaatgtga tcgaagttta cgaaggagaa ctaaaaagct ggaaccgact gacagaagag
     4861 tttgagtttg atccaaatgg tagaacgtct gatgaagtca ttggatatgt tggctatttc
     4921 gagttactga atggattcaa aaaaactgtc tattggacca aacaagaaat cgaagctcat
     4981 cggattgcta acaataaaga tcgcgataag acaaagttaa gtggtgtgtg ggcatctgat
     5041 tacaatgcaa tggcacgaaa aactgttttg agaaatcttc tttctaaatg gggaatcttg
     5101 tccatcgaaa tgcaagaagc caccacatcg gatgagagag tccaaagggt tcaagaagac
     5161 ggcagcatta ttgctgaaac agaagttgaa gaagatattc ctgaaagaaa agaagcagag
     5221 gttatatctg aagaaaatga agatgtacaa actggattat ttgatgcatc taatccgccg
     5281 ttaaacaaat aatgagggag ctttctccct tgcttttcta gaggagaaat acgaatgaac
     5341 acaggatatg tcaaattaca tcgaaaagtg atgaattcat tcgtttggac caatccttat
     5401 atgtataaat tatggaactt gtgtttgatg aaagcgagtc atgagaatcg caagatactt
     5461 tttaatggaa aagagataca agtgaacagc ggagaattcg tcacagggcg cgatgctatc
     5521 acatctgaga tgaacgaagg cgtgaaacgt gaacatcaag tgaacagcgg ttctgtatgg
     5581 agatggctaa aacaatttga aaaaaacgga atgttgaaca tcaaatcaac tacgaaatac
     5641 agcgttatat caataaaaaa ctggtctttg taccaaagca gtgaacaaca aatgaacatc
     5701 aaacgcacaa caagtgaaca acaagtgcac acaaacaaga atgaaaagaa ttataagaat
     5761 gaaaagaata ataaaacatc atcgtcgcaa ccacgcaaaa agcgtgttta cgacaccgac
     5821 tcagtttact acattctcgc ggaggagtta ttcaaacaga tttgtcagaa tcaggaaatc
     5881 aaaaagccga atctgcaaag ttgggcagat gacattcgga aaatgatcga gatcgacaag
     5941 cggaccgaaa accaggtacg gggaatgatt gaatggagtc agcacaatgt gttttgggca
     6001 tcgaatattt tatctgctaa aaaattgcga gaaaaatacg acacaatggc agcgcaagca
     6061 aatcgtgatt ataaaacaaa acaaactaaa acgcttgaat acgagaaatt tagcacagat
     6121 gagttgccta tttgagagga ggcgtaggca tggaaactgt tggggaaatc atggaaaagc
     6181 tgatacagaa agtgcttgtc caacgtggcg aatgtcctga atgcggacag cctttgtatg
     6241 gatggcgtac gaagaaccct gatggctcag aacgttgtaa gccaacctgt atgcaatgtg
     6301 ggtataaagc attgcgagtt caggaagact tacaaacaga acgaatttac aacgagagcc
     6361 tgaaagcaag agcaatcaat tttttcaaag gtggttctgt tgtgcctaat caagcgttgt
     6421 ttgattgcac attgcagaat tatcaaattg tcgatcaaga aacaagacaa gcggttgaag
     6481 taaccaaacg ctttgttaat tcagtcttgt taggaaatcc aagtcacctt gttttaactg
     6541 gaaaacaagg aacaggtaaa agtcacctag cgatggcagc ggcttgggaa gtcttgaagc
     6601 gatcaaacta cgataaaaaa atcttattta tcgggttaca ggaaatgctg gatcaaatca
     6661 aattttcgta caacaatcct gaactcagaa aaacgattga gggatcgttg attgcagata
     6721 tcaaaacagc ggatttagtc atcattgatg atatcggttc agaactagga aaagatgcat
     6781 cagatagtcg agcgtttggc ataaacacgc taaattcgtt cttggatgca cgacagaacc
     6841 tagcaacgat tatcacaacg aacttgcttg gtgaagaact gaaaaaagct tacggtacga
     6901 gaacaatatc aagaatgttt gtcaactctg atggatttac gatggtattt tctcaaacag
     6961 cagacaagcg cataaaacca gtcaaaggag cgatcgcatg aatttgacta aacaagaaaa
     7021 aagaatctgt cgtcagataa tgttgcaaat tataggtgat cgtgacatgg acgaattatc
     7081 tcaacaagag agtcgaatgg ttcggaagat aagtaagcta attatttatc gggatacaga
     7141 aagatttctc actgttttag gtaacgtcta cgagaatcca gagttattgg aggtagagta
     7201 attgccaaaa atattagatg catgttgcgg tagtagattg ttctggtttg ataagaacaa
     7261 ttctgacgta acatttatgg attgtcgtca gcagtatgaa gaattatcaa caggtcatgt
     7321 gatcaatgtt gatccagatg tggtcgcaga ctttcgcgat atgccttttg aagatgatgt
     7381 gttcgatatg gttgtatttg acccgccaca cttaagacat gtcggcgaaa actcatggct
     7441 tgccaaaaaa tatggaaaat tagacgaact ttggccagaa gacatcaggc aaggttttgc
     7501 agagtgtatg cgagttttac gaccttcagg aacattaatt tttaagtgga acgaggaaca
     7561 gataccactt tctgatgtgt tagaggctat tggagaacag ccattgtttg gtaataaacg
     7621 aagcaaaaca cattggcttg tgtttatgaa aaaattcagc taacggagga aacaaaggag
     7681 gaaaagtaat gaagattgta ttaaataaat gttttggtgg ctttgggttg agccatgaag
     7741 caaaaatgga aatttttaaa agaaaaaata ttgaagtatt cccatacatc aataacttta
     7801 gctatgactc agatgatgaa tacacgagat acacaggcca aaagctaggt tcgatggatt
     7861 ttatctacta tttcaaaaaa gacccgaaaa tcgacaaagt tacaggaatt tatagcgaaa
     7921 ttgaccgact gtacggaatt gctgatgatt ccagtttttc aagtgattca aacagaggtg
     7981 ataaggacct cgttgctgtt gtcgaaaaac taggaagtga ggccagtgga ccatatgcaa
     8041 gtcttaaagt cgttgatata cccgatgggg ctgagtggga aataagtgat tatgacggcg
     8101 ttgaaactgc acattatggt tttcaaacag gtagtattta gtccactaat gacaactaaa
     8161 gaggaggcag aaggatgagt gaagatgaat actttgaaca gtagtctatt aacgacagag
     8221 atttttaact ggaaaggggt gtagtcatgg acgcatcgga agtagtaaat aaaattaata
     8281 gtctcaaaga ggttttcgga gacgtcgaag tagtgataaa cgcacaaggc tatgacaacg
     8341 aattttttaa gcagattacc gacattagca ttcagcaagg aatggaagac gaagacggaa
     8401 actttatcga tgaagtagcc attttagtga cttgcgagta agtaattgac agctaaagag
     8461 gaggaagcgg aatgaaacta aaagacggat tttactccag cggccacggc atcggcggtt
     8521 taatgctaga tatgccgaca aagaatccta aaacacgtaa gaaaccaaaa ttcaaagtcg
     8581 gtgacatggt tcgctgcgaa gcagaaggat tcatctatcc atttcgtgga tatgtagaac
     8641 acgtctataa tcactcagca atcattcgca ttgaaaacac gatggaatgt gataagtggt
     8701 tagcgaaaag caaagagaat ttagcagtgg tgagattggt ggacatggaa gttataaaat
     8761 cttaattttg cttttttaca actatcctac aacaatgagc gttattccac aactggaagg
     8821 agaagaggca attgtgaaca ttttagagaa tatagatatt aagcaaacaa ggaaaaatgc
     8881 tagacgatta ctaaaaagat acagaaattt agaacgtttg gtcggaccag tgaaaataga
     8941 cttttccgtg atgactgtta ccaaaaattt gaaattcaca attgacagtc aaaacgaaga
     9001 aatcattgaa gcgataagta ctcgagattc ggttatcgaa gcattaacac ggctaagtag
     9061 aatccatttc caggtacttt attatagtta ttgttttcct aataagatgt caatgtatca
     9121 aataggagaa aaattaggat attccgatag aactatcgag agaatgaagg cagtagcttt
     9181 ggttgaattt gctgaggcgt ataaatcagg agaactcatt tcacgtacaa aataaaaaaa
     9241 gtcggattcc tccgactatg aataatattt ccgacataag tattatatca taattggggg
     9301 aatcagagga tggtactttt cgatgtaaag aaatatgaga caccaagcgc gaaagatgtt
     9361 gatatggaac gcacaaaaca taatgtcgct gtgtttcttt cagcatatct atcagctaga
     9421 tgtagagtag ggcaacatcg agaaccaaaa gtgacagcat cttattcctt ggttccacct
     9481 tctacagctg atcatatatt tgaagcagaa agaatgctga tcgataaaga agaagcacag
     9541 gaagaatttg agtatctgca taaattgttt gttcgaggct attcagcgat acagcatccg
     9601 cataagcctg atgtgactga aaggcgcaag aagatattct atgatcgtta tatcaatggt
     9661 ctgcccattt atgtaactgc tcaaaggaat aatactagcg aagaatcggt taaagtagaa
     9721 tcaaacagaa ttatcatcca atttgcttca tcgttagaac tggttgcttt caagtagcca
     9781 gtttttacac tttttatacc cttttattac caatttggtt tccattttat acctttttta
     9841 taccaatcac ttacctattc aacgttgtat tatgatagtg tcgaaaaatt aggaaacagg
     9901 atcgacaaaa taaaatgtaa gggaggaaat ctccctcatc gtttaattaa gcttcgatag
     9961 gcagcaacgg aaatattaag aataaggatg tgaatttcaa ctccttctaa attgttctta
    10021 ttatctatca tccgttgctg tctattgttt ttttaattat tcacacgata actaaaggta
    10081 agtgaagaga aatgattcca ttaataattt caatttttgc gctttgtctt aatgtatata
    10141 tgattggatt taaaaatggg caaaataaaa aatagtagca gccaagaata attttatagt
    10201 gtcactgtgg cggaaagggt agacgctaag catgtgtgct aggtcaatgc ttcggcaacc
    10261 atgcaaggtt cgattccttg ccagtgactt tggcaaccga ggcatcggcg gtttaaaaat
    10321 ataggggtgc gcaatttcgt acgcgttttg tgcatcgtgt aggttgctat tacataactg
    10381 gttaggttag attgagattt gggattcggt acaaatgaat cgtcaaatgt ctcaagcaca
    10441 ggatcggaaa cgtccctgcc tgtgcattac atattagatc actctttgag tggtcttttt
    10501 ctttacataa aggaggctac ataatgagaa actactggta tgtatcgcta actaatgaat
    10561 atcctcgaac cattgatgat tgttcagtgc gtgttgtgcg ttctgtacaa atcaaaggga
    10621 agtactctat tgtcgaaatg gggagagaag cagaaccatg tgagattgat gcgtgcaagc
    10681 tcgtttattg cggtcatggt ttctatgatg aaccaaacat tcaaaataat attaacaaga
    10741 atttgaggga ttagaatgca agaaatggct taaaaatctc caatcaggac aaatcaagtt
    10801 agacaaagtt tccgatttaa agatattgat tgaagctgat ttaatgctaa aagatattga
    10861 aaattagaaa acaaaactca acctaaacag aatgtgaggt ggtgtgtatt gaatggcaag
    10921 acaacgtgat ccaagacgtg atgaagccaa aagaatttgg ttagaatcca acggagaaaa
    10981 gcagttaaag gaaattgcat ctgaattaaa tgtttcagat tctcaggtta gaaaatggaa
    11041 atcgcaagac aaatggagcg ctgaattgat tagtaacgtt accaatggca aaagtaacgt
    11101 tactaatcaa ggtggcgctc ctattggtaa tcaaaatgct aaaggtaaca aaggaaatag
    11161 ccgagcttct ccgccagtgg gtaataaaaa cgctttgaaa acaggtgagt atgaaacaat
    11221 attttttgac acgttaaccg ataatgagaa ggacatctat tctagtttga atgatgatcc
    11281 ttcttttgct ttgtccgaag aaatacgact tcttaaaata agacaacttc gaatgatgaa
    11341 aagaatccaa caagctgaag ctggactaaa tgatgaagaa gtcgaacgat tgcagcagct
    11401 aagaaagatt aaaactccga ttgaaaaaaa tggtaaaaag ctagaaatca agcgtgaggt
    11461 tatgcaagat gtgcagatta gcagaaaaaa acatcgcaaa attgatgata ttctttcaat
    11521 tgaagattca ttgactcgga ttagcaacca gttagctaaa gccatcaagc aaatgaatga
    11581 actttatatg aatgaataca gaactgattt aattaaagct cagactgata agatccaagc
    11641 tgagacaaat gaaattggcg gaaataattc aggtgaagaa atagaagaat ggaaacaggc
    11701 agttttaaat gccgcaaaca aacgggcggt gaaagaaaat gaataatgaa tttattcctt
    11761 ttgctgatat tggttctgcc attgattatt actatgataa accagtagct ttttgccaag
    11821 atattttgca tttgaatcct gatgaatggc aagaaaatgt tttaaatgat ttagctgaat
    11881 tttcaaaggt ttctgttcgt tctggtcaag gagttggaaa aacagcatta gaagcaggag
    11941 caatactttg gttcttaacg tgtcgaccct acgctaaagt aatagcaaca gctccgacaa
    12001 tgaagcaact ttacgatgta ctttgggcag aggtagctaa atggttaaat gatagcttga
    12061 tcaaaaactt actgaagtgg acaaagacca aaatttatat ggttggtgat tcagagcgtt
    12121 ggtttgctac ggctagaaca gcgactaaac cagaaagtat gcaaggtttt cacgaggacc
    12181 atatgttgat tgtggtagat gaagcttctg gtgtgtctga tccaattatg gaagctattc
    12241 ttggtacgct atcaggtttt gataataagc tgttgatgtg tggaaacccc aataatattg
    12301 aaggtgtctt ttatgattcc cataattcag accgtgataa atacagagtt cataaagtat
    12361 caagctatga tagtaaacgt acaaacaaag acaatataga aatgattctt aaaaaatatg
    12421 gaaaagaaag tgatgttgct cgtgtccgta tttttggaga atttccgaaa ggtgcgttgg
    12481 attcatttat cagtcttgaa acagttgaat tggctacaga aaaacaaatt agtgattctt
    12541 tagtcaataa aacaaaggtt gctcatattg gtgtcgacgt agctcgatat ggtgatgatt
    12601 ctacgattct ctttcctaga attgctacca gggcattgga gtatgagaag tattcaaaac
    12661 gtagcaccat ggaaacaaca ggatatgtca tcaacatggc caagaatcta atgagtcaat
    12721 atccgagtat tgataaagtg atgattaaag tcgatgacac tggtgtcgga ggtggtgtaa
    12781 ccgaccgcct agaagaactt atagaagaca aacattatcc ttttgaggtg tttggagtga
    12841 ataacggttc aacatcagaa gacgattttt acgataattt aggtactcaa ctatggggaa
    12901 acatcaagga aatgttagaa gaaaatatga cagcaaatct taacggagaa cagcctgtta
    12961 ttgaattgcc ttctgatagt tcgttaatca aagaattaag tactcgcaaa ttcaaaatga
    13021 caagtagaag tcgtatacgt ttagaaagta aagatgatat gaaaaagcga aatattggta
    13081 gtcccgatat tgctgacgca ctggctttag cgttttatga gccaccaagt cactatcaat
    13141 ttattcaatt ttaggaggtg agcttttgat tagtacagta ttatctttag agagatataa
    13201 gaagctacgt gttaaatatg caacacaaat tgaagatgga atgtttgatc cgaatggttt
    13261 tatagaagat atgaaaccat tttttgctga tcgcgaaaga aaatatctag cttatactag
    13321 cgaaaagaat gaaatagata atagaccaaa gcctaacact gatattgtaa aagttaataa
    13381 taaacttcat gctggtatgt attcaattgt cgtagaccaa gcagtcaatc attttactgg
    13441 tatacctatc aaatgggatt acgatgtatc ggaacaaaaa agaacactca ttcaaagatt
    13501 aaaagataaa ttcttaaaaa atgatataga acttccgaca gttccagaag cttttaacaa
    13561 attaacaagc aatcttgatt ccatgagatt cgcaatgctt gattctgaaa ctgcaacttt
    13621 tcaaggagct tgtggagtag ctttccgatt gctagagcct gtggaagaag atgatggttg
    13681 gaagttaaga gcaagtaata ttgaaccttg gagagcagaa agatatggaa atgccggaat
    13741 ctatatcaaa gaaaagtatg actcttacca gaaaaaattt tttcaagaaa tgaaagttat
    13801 gacaagaaat aaaattctga catatgcttg ctatggtgat ttgaattttg ttacaagcgg
    13861 aacgttcaaa aaaattgatg agaccgataa ccctttgggg acgattacct tggcagaatt
    13921 taaaaataat acgaatcgtt attgtgattt tgaagtagct gaggaaattg gagatgcaat
    13981 tgatcgtgct ttgtctgatc aacaaaacga aatcgaacaa tttaagcttg cgtacatgct
    14041 tgttactggc acaacaatga gcaaaggcac tgctaaagaa atgatgaatc agctagggat
    14101 tatcaactta aaagccccta ctgcaaaagc tgaatatgtc acaaaaaatt tagcaaaaga
    14161 tttcaatgaa tatcatatgg atctattgaa aaaacagttt tacaccattt gtaaagcaat
    14221 cgattttaac gatgaggtgt ttaaatcaaa cagttctgga gaagctcgca agtggcaaat
    14281 cattagccta gaagcgaaaa caaatactaa agagcaatat tttagagaag gattgaaaga
    14341 atgcgcagaa acaattgctg cttttcttaa gtttcatgac aaagtagaaa ttgagcctga
    14401 aaaaattatt tttactttct ctagatcttt gccaactgat ttaagttatt tagctgaagc
    14461 tttacctaaa cttgcaccat acgtatccaa acgaactatt cagagccaaa ttccatttgt
    14521 aacagatgtt gattatgaaa atgaaatgat ggaattggaa agtggaagtg cttatccaga
    14581 tagtgaatac aattttggcg gaggtggcaa tagtgacgat agaaacgaag tattggacca
    14641 aacgtcgaga actggaggat caagcaaggc tcaaacaaga aaatcagaca cttaaaaaat
    14701 taactagtgt atttcctgaa gcactgaaag agatacaagc aaaactatta tcacaagctg
    14761 acttacacaa tatcacttat ccagaaatga tggagtttta cagtacaagt aatcagaaaa
    14821 aatatcgtga atatgtggaa aaaaattata agtcattaaa aatgtatgat gcaaaataca
    14881 aagagtttat cgatgaattt tttccaccat ttgactatgc aaaagtcaat cgcttattac
    14941 aaatacgatc agatgtattt aaaattcttg cagaatatgc gatggatgca gatgtgaatc
    15001 aatatttttc tgatcgctta gaggaaattc ttcaaagaac atattcttct aatgctaatg
    15061 tttttgttca acttttaaac gttgatatac caaattattt accagaaaat gaaattaaac
    15121 attatttgaa ctatccatgg tcaggaaaga cattttcaag aagactttgg ggaaatattt
    15181 catcgcttga acagaaactc tctaatgcta ttgtaaaaag tgttgctagt ggagaaggcg
    15241 ttatacacgc attaaacacc atgagattag actcagaaat ttgtgacatg tttaagttag
    15301 aagaatcaaa gtataacaaa gcgatagaaa atctcgttcg aacggagtat gcaaaatttg
    15361 cacaagatgg tattgaaaaa tcatatttag aaacaggtat tgaggaatac aacgtattga
    15421 ctgcaaaaga tgagagagtt tgccggattt gtggaggaaa ggcaagtaag aatccctata
    15481 aactgaaaga tgctgtcata ggtgaaaatc gagcaccttt ccatagtcgt tgtagatgta
    15541 cggatgttcc taatttacca aaattaggaa aggatattga tgaagaatat gaccgtttat
    15601 ttggcgattt attagatgag tttgcacatg attcttttgg aattaatttg aaacggagga
    15661 agtagaatga aagatttttt tgaagcagta ctaacaatta atgtaaatgc tgatattgca
    15721 gaagcctaca aaacagctat tgagtctgag aaccatccta atggcttgag agaccattgg
    15781 aatggcaatt atgcctacgt ggttattggc gatcaaactg ttaattatca agataatact
    15841 ccagttgata agaataccgt taatttaacg attcaattat tatctcattc attaccaaat
    15901 ttaaaagaaa cagttgattg gtatgaaaag atgggatgta ttgttgttag aactgactac
    15961 aaagaaggaa agtctagtaa ttaggctttt ttattttgtc cgaaatgacg ttaaactagc
    16021 gcaatactgg gcttggttga atggtggggc gcaactatta aaactcaaag caatgcgggg
    16081 cgtgaaaacg aatcgtgggg cgaaaggaga atgagcatga aacacaaatc attaatgcca
    16141 atgaatttgc aatactttgc cgaaggtgac gatcaaaagt tttcttttga tgacttcaaa
    16201 tcttttgtgg aatccaatga agaagctcaa aaatttattc agtcacaatc tcaaagtgtt
    16261 gccgacaaac aattggaagc ttggaaacaa aataacttag ataaaattaa acaggatacc
    16321 atcaaggaat atgaggaatc taagaaaaac aagtcacctg agcaaattca actggaaaaa
    16381 ctacaagctg aatttgaagc agaaaaagcg ttgcgtgtga caagtgataa taaagcattt
    16441 gttgcagaac aaattgctgg attagaacta gatggagagt taaaagagtc tatttctcaa
    16501 tttatgctaa ataatcttgt tagttcggat acagatttca ctaagaatgc tgttgaaggt
    16561 tttacaagtg ttttgaatgc aattaatgag aaacatgcag atgcattaaa agaactacaa
    16621 atgaagtctg catttggtgg aactcaacaa tcgaataacc aggttcagca gaacaatgaa
    16681 acattaacaa atccagaaga acaattagga caaattcttc aacaatttaa ctaggagagt
    16741 gaaaaattat gaaaaaaaca tctttaaata atttagagta tttggatatt tcaccagcga
    16801 ttaatgctat gcaagtacca aatacacctt ttttaagcta tttacttggt gctggaaaaa
    16861 cagagccagc aaactcgaca gaaattaaat ggcgtgaata tgatatcaac aacgatgatt
    16921 cttctgaaaa acttgagggc ggagaatatc cagatgctga atcaggtcga acttggttta
    16981 acaactatac tgaaattttt agaaaatcaa cctctgtatc tggtacatta gatgctatta
    17041 atgtgaatgg agtcggaaat gaattaacta atcaagtagc actacgtggt atggaaatga
    17101 aaattgattt gaaccgaaaa ttgattactg gtgtaaaagc tgatgaaaat ggttctaaag
    17161 gtcgtcgaat gaatgggatt ttgaacttga tcaattcagc aaataaggca gaaacagcca
    17221 ctgcgggtgc agtaacaaga aaagatatcg atactttatt taaattgatg tatgaaaaag
    17281 gttatatggg agaaaaacta tgcttgattt ctccagatat gcaggagtta atgactgatg
    17341 agttagatgg aaaatcaaca aaaattgttc agttcgggga aagagtaact tttggattgc
    17401 aaattggaaa tatcgtgtct aattacggta caggtattgc tctactagaa ccatcattgc
    17461 caaaaggaac aattgccgca atcgatacta attatgtgaa actacgtcca ttacgtgaat
    17521 ggagagcaga agaacttgca aaaacaacgg attctagacg tatcggtctt gtaggtgaat
    17581 actctcttga atacaatgct tcaaactctg gggcaatttt aaatttaaag tctgaataaa
    17641 agggagttag tactcccttt tttgatagga ggaattacag tggtaaaaaa agatgaaact
    17701 aaaaaagatg aagtcgtgaa atatagagta ggtaaaacta aaaattttgt tgggtttgtt
    17761 catcctaaaa ctcgtagatt tatcacagca gattcaaata acgaatttat catttctata
    17821 gatgataaag aagcaattgc aattttggaa gatgcaattg atgttaatga aatttaggaa
    17881 gtgatctgat ggatgaatcg ctaaaaacgg aaatcattga gtctacaaaa gaagattttc
    17941 cagatttgag tgaagaacgc ataactaatt tattagaaat aattttgcta gaaattgaat
    18001 catacaacac ttgtaaaaat gatatttcat gggaaaagtt aaaaagcgtg attagtgaag
    18061 tgttgtataa aataataaaa aatgaatcag aaaaaacagt atcttcagtt agacgtggcg
    18121 atacaacgat tagttatgct tcaacaacaa atgatgttag tgagttactt ctaggctatg
    18181 gtgatttgat acgaagagtt attggttgtg gaggattgga gtttttttaa tgaatgaagc
    18241 agatatttta gaaactactt atgaagatag ttgtattatt gaaagactga cggacattga
    18301 agattctaat acaaatatta ctattcaaga ttacaaaaaa gtatatgata atcctatttc
    18361 ttgcgctctt tcacaaggtc aaatcgatgg actagcagtc atagaagatg gagagatggt
    18421 aaatgtttca actgacacat ataaattatt tgttcatcct aagattaaac taaaaaaagg
    18481 agatcgaata acaataactc aaaaggccag tggcttaatt ttttctctat ttgctactaa
    18541 gcctttttac tatcctagtc attgtgaagt gaatttgata ggaagtgaga aaaatgggta
    18601 atctcaaata tgaatcaaat gcagaaaaga tcattgagaa ttttaaaaat atgactgtaa
    18661 ttgctcaaaa agaaggaata tccttcgtta acgattcaat gaataaagtc gttagtttag
    18721 ctaaaccatt aactcctgta aaatcaggta atttaaggcg aggatatcgt gtagtaaaag
    18781 ctagaaaact atcaagcggt cgaattgttg gagaagttat aaacaatgaa cattatttta
    18841 aatatgtaga agaaggtcat aggactaaaa atggtggctt tgtcaaaggg aaattcatgt
    18901 taactcgtgc aacgaatctt gcaaatatgt cttatattcc tcgaagattt aaacaaatgg
    18961 caataaaaat cgttaagaaa ggaaagtaac atgaaagatg aaatcattgc tgcaatcagt
    19021 agcaaattaa aagaaatcta tcctgatggg acaatatatc ttgattcagt tatgcagtca
    19081 actaaagatt tttatttcgt tttatcagta atggaatctg gaactgaaaa tgtaggaatt
    19141 gatattcaaa atgtttcttt cttaattgat attgcattga ttgataataa ccctaataga
    19201 aatttaatta atgaattagt ctcacgttgt gggacttttt ttaatacgat tacaatcgat
    19261 gagcaaatat tatttccaaa agcctattta cctgatgaag cagatggtgt tcaacatatt
    19321 cgttttacat tagaatttcc acaatatatt gaatggagtg aaagataaat gggagaaaaa
    19381 agaagtaaaa ccggaattat ttctgtcgaa aaacctactt ggtttccttt ggaagatgag
    19441 acagggaatt ttccggtata tggtactgcg ttgccaatgg gaacagcagt aagtatcaaa
    19501 ccaacagcta attatgaaac aacacaagat tatggggatt cagtggttca agatcaattt
    19561 acagcttttg gtggtgcaga agttgaactg gaagcaaatg gatatactca taaagtttta
    19621 tctacaatta ctggagggaa aattgttaaa ggtggtgcct tgcgttctgg agaagatatt
    19681 gcgcaagatg gtgcgtttgc atatagacgt aaaaaatcga atgggaaata ccgttatacg
    19741 gtcttttata aaggacagtt tgctctagat tcagatgaaa catcaacgat tgaaggaagt
    19801 aaagtaagtt ttactcatcc aacttggaag ggttcatttg tagatgtacc aggacttgga
    19861 tatatgtatt cagttgatga agatgatgaa ggcgtggata aagcaatgat cggaaattgg
    19921 tttacaaaag tagcaattcc aattgaagaa gcagaacttt caggaggtac agaataatgt
    19981 caaaatatca aacaacgatt aaattaacga aaaaagacga agaaggtaaa tatgagcaag
    20041 tacaatttaa atctgctgaa tttttaccag gaacagttgt agaagatgct gcaggagtta
    20101 tggaagaaat gcaaacagcg actgataagc aatcagttaa aaaagcttta agtcgtgctt
    20161 attcatttat tgcagatact ttatttgagg gacaatttac tggtgaagat tattgcaaag
    20221 gaattgatgc tcgtgagatt gcctcattga caggaaaatt attgaagtct gttactgcag
    20281 gttttgatga aacttataca gagacgaaaa aaaagtaagt gaggcgctca agtcaccttc
    20341 atttaagtat tcgattactt accgagaatt agatataaag acgcaattac tcgaagcagg
    20401 ttggacgtta ccagaaattg aacgtactga cttggatgag ttaatgcgtc tttttgcttt
    20461 tagagatgcg gtaaaagagc atgaagatgt tgagtactat gataatttca ctcaatttta
    20521 ggaggtgata ctttgaataa cgatgaccta attctgaaga tgatactaga tgaatctggt
    20581 tttactgccg gtatgaataa tgctgtcaaa aagttgaact cttttgatga aacaatcgaa
    20641 agaaaaagta gaaatagtgg cagttcatta ggtagtattt ggaaaatatt tgctggaagt
    20701 tttctagcta gcggagtaac tagaatcgta ggagctggct ttgatctaat caagggttcc
    20761 ataagtggag cggttgatcg agtagatacg atgaataacg ctctacgaaa tttccaaaat
    20821 atgggattta gtaattcaga aattatgaag aatatcggaa agaatgggct tttatctcaa
    20881 ggtattcaag gacttcctac tgctttgaat gatgcgataa gtcatgttca acttcttgct
    20941 tcttctacag gtgatttaac tcgttcaact caaatattta aagctttaaa tgatggaatt
    21001 cttggtttcg gtggttcaac tgatcaagtt aatgaagctg ttattcaatt atctcaaagt
    21061 ttctcaaacg gaaaagtaga cgcacaaact tggaactcaa tgatcaacgc tcaacttgga
    21121 cctactcttt ctgctattgc taaaaagatg ggaattacaa tgggagatct gaaagaaggt
    21181 ttatctcaag gtaagatttc tgttgaagaa ttccaaaatc aattaataga aatggatacc
    21241 aaaggtggcg gaggacttaa atcattaagt caaatcgcta aagattctac taagggaatt
    21301 aaaacctcta tacaaaatgc aaaaacagct gttacacgtg gtgttggtga ggtaatagaa
    21361 ggattaaata aagcattagt agattcagat ttaggtggat ttaagggaat tattgataaa
    21421 gtgggcagtt caatggaatc gttcttaaaa gtaattgctg caaatattcc tacagcagta
    21481 tcatttttaa gtaatttatt taacgaaatt caaaaatttg gttctgcttt gaaattcatg
    21541 atgccctttc ttgttcctgc agctaccgct tttggagcgt tcatgtttca acttaaaggt
    21601 ataccagcaa taataaaaag cttcaataat tttaagaatg ccataattgg cgttggaaat
    21661 tcattaaaga ttatgggggc aatagctgct gctaatccat ttgttttaat tattggtgca
    21721 gtcgttggtg caatagctgt tttcggttac tttatggcaa ccaatgaaga gcttagaaac
    21781 aaggttatat ctatttggaa tgatgtgaaa gattccgtaa ttggtgtatt aaaaaatata
    21841 aaggactggg gaattgatac ttggaattct gctaaagaaa tggcatcaaa tgcagttgag
    21901 ggtgtcaaag atgcttggtc aggaacaaag gaatggtttt ctaacacctg gaaaggtatt
    21961 aaggatgggg ccacaggttt atttgataaa acagtagaga cttcaagaaa tgcagtcgat
    22021 agtgtaaaaa atgcatggtc taatatgaag aaatggtttt ctgatacttg gcaaagtata
    22081 aaagattcag ccagagaaaa atggaatgga atcaaaggtt ctattatgtc agttgctggt
    22141 ccattgatta caggtataaa gaatgcattt ttacatgtta ctttttatct agagacctta
    22201 tggaataatt tagttgagat tggtaaaaac gtctttgaga ttttaaaaaa tgttatactt
    22261 gcgccggttt tgtttattac ctccatgatt tctggtggat gggaagaaac aaaaaataat
    22321 atgattgctg tttggaataa tattaaagaa agtgccataa atatttggga atctataaag
    22381 aatatatttg taagttattt tacaaatatt tattttgctg cactcaatat ttggacaggg
    22441 ttcaagctta cattgataaa tatttggaat gaagtggtaa atcaagctaa atcgatttgg
    22501 ttaaacataa agtatttttt tattaatctt tggattgata taaaatattt tgcaattcag
    22561 aaatggattg aattgaagtt ttctattatt caaacttgga tcgatttaaa atataatgcc
    22621 attactactt ggaataatat taaacagttt ttcaaagata cttggaaaaa tattaaagat
    22681 acggcataca atacgtggat ttctataaaa aataccatga ttaatacatg gaataacatt
    22741 aaggactctt tctggaatat tgttactgga attgttaatt ctgctgaaaa tgcatggaca
    22801 aatctaaaaa atggtgtttc aaatgctatt aatcgggtaa aagaaatctt taattcgtta
    22861 agggaagtca atttatttga aattggcaag aacatcattg atggacttat aaatggtgta
    22921 aaagaaaagt ggaatgcttt gaaagatact atcaaaggta ttgcaggtaa tatcaaaaat
    22981 tggattaaag gagctttaga tattcattct ccatcaagat ggatgcgtga tatggttggt
    23041 aaaaatattg ttcaaggtat tatcgttggt attgataaag agcaaagtaa gttagatcaa
    23101 accatgacaa atttagtaaa aacaccgtct gttcaacctg tagtaaatgg aataagtcac
    23161 ctaccaatta cacaaacaaa gcaaaatata tctgctagtg aaacaaaaga aattcattta
    23221 catttaaatg tttatggaga tttacctgat tcaatggttc ggaagattac cacaaaaatt
    23281 aaaacagaat tgacaagaca aatgaaacga gatgctggtg cagtaggagg aacattatat
    23341 gcaacttaag agaggacaat tttttattaa tcaacattat tcttctgaat ttaatgtgta
    23401 tattcaaaac aggcctgctt ctgtttcagc tagtcgagta attgaattga gagagcgaga
    23461 aggaaatgat tctatcatta ttgataaagg ctattacaaa aatgtgacta gaaagattga
    23521 gtgttactat aaagcacctt caattgatat ggtgcaggag tgggaagatc gaatcactga
    23581 atggttagat atgtcgtctt atagtgattt tattctttac tatgatgaac aatatattta
    23641 tcaagctgta gtaatagaag gacctgaatt taaaggaaca agaaaaacag gaaatattgt
    23701 cccttttgaa tttacagtga gtattcgacc atttaaggaa aattacaatg gtagatttac
    23761 tattcgacaa acagaaactt ttgaaattta taacccagag aagtattctt caaaaccgct
    23821 tattaaattg agtggttctg gagatgcttc tttttatatt aataaggata aatatgattt
    23881 gaaatcgttg gacagagaat tatttataga ttctaaatta gaagaggctt atcgaaaatt
    23941 agatggtaat ttagaacatc aggatcaggt caccttattt ttagattttc catttttata
    24001 tcctggaaaa aatgaaatta aatggacgaa aaatattcat tcatttgaaa taatgcctag
    24061 gtggtggaga aaagtatgaa accaagaata tatagtccta ctgaaacaga tttctcaacg
    24121 aatggcttag gaattttaaa ggattgtaca agatgtggaa tatatgaagt agctaatgga
    24181 aaatatgaat tagagttgga ttatccttta ggaactagat ttgatgaata ttttgaaaat
    24241 gactatcaaa taaaagcaaa gccaaacgat caagaagagt atcatatctt ttttattgat
    24301 gataaagata tagatacttt tttaaataca gtaactattt atgctcagag tcgtacaaat
    24361 cgacttggaa gacgggtagt cactcttgtg gaagtggact ctaaaactgg tcaagaagcg
    24421 atatcaatta ttgaaactaa aatggataaa aaatctgaca tacgacttta ttctgatatt
    24481 acggctgttt ctagcacaat ctttgaagcg agaaatgttt taaattgtat tgctggtgaa
    24541 caaggatcat tgcttcaata ttggggcgga gaaattaaac gtgaaccatt taagctttct
    24601 ttgttaaagc gaagaggtcg caataatgtt ggaacgattc ggtatggaaa agatatgtct
    24661 ggtttgaagg tcaaattaga ttggacaggt ataaaaacaa gaattattcc atatgctgat
    24721 cctcaaagtg aagtaggtac gactaatcga atttatggtt cgccagtaga tagtgcctat
    24781 attaataact atcctgatgt ctatacagaa catgttcagt ttacagaaga acaaggagta
    24841 aaagacatta agagcttaaa taaaatagct aaaaattact ttaaaacgat caatcctggc
    24901 tgtgataagc ctaaagtttc tattacggtt gaatttgata agttgactga tagtgaagaa
    24961 gcgaaagaat ttgcgaagat tagaaattat ggtctgtttg atacatttaa aatatatcat
    25021 aaaaaatata atatttatct tgaatcaaag gttagtggac tacaatacga ttctttatct
    25081 gaaaaaactt tgaaattaga agcaggagac attcaagttg ctttttatca gcaacaagct
    25141 gtaactattc aggataaatt aaaagattat gcaacgaata attatatgag tgattttaat
    25201 gattatgttt cttcaatgat tacaggtcaa ggcagtgcag gaggatatgt agttttatgg
    25261 ccaaaagaaa aaccttccaa catctttatt atggataatc cagatttaga aaaggcaaga
    25321 gaagtactaa gaatgaataa aaatgggatt gctttttcta agaaaggatg gcgggggcct
    25381 tttaattcag cttggacatt agatagtata tttaatgcca attttataca aactggatta
    25441 atcaaagcag atatctttca aaattctttt aacaagactg gagatgtatt gaaattagtt
    25501 aatggactac tccaaatttg gaacaacaaa aagaaaataa tggagttaac taaaaaagga
    25561 atggaatttt ggaattctaa gggttcaatt ggaacgattg gaacaactga ttctgttggt
    25621 aatccttttc ctggggcttc tactccaacc cctattgaag ataattcttt agttattcgt
    25681 acaaatggag acggcaaata tattttgatt tctcctaaag taggaaaagg attagtttta
    25741 ttaggaaatg gtaaagcaat ttattttgga gacttagatg tacaaggaaa acttacagtt
    25801 aaaggaaaag aaataattcc tggacaaggt ggtggtccat cgggaggtgg agaatctact
    25861 ggtgggtatc ctagtgaatt aaaaacagat gcagaaaaga gagcttggag aatttacgat
    25921 attttgtgta ataacggatt tacgaaacaa tctgcatgtg gaatattggg gaacattcaa
    25981 caagaaacag gaggaacttt tgatcctgat actgttcaaa taggtggacc agcatacgga
    26041 ttagttcagt gggatggttc ttcatatcct cttgttggtc cagcaacatg ggatggaaaa
    26101 gtttatgttc aaaacttatt taatgctgca ggtattaaag aaccaataac gagcttagat
    26161 gcacaagttc gattgcttat ttggacattt acaaatggac aatggatggg cgtagtacaa
    26221 cctacgacgg ttgatggatt taaggcctgt actgatccaa gacaagcagc atatgctttt
    26281 gaacgaaact atgaacgtcc ggcagcgaca catcctgaac gtcaagatta tgcagttaac
    26341 tggtataaca aatttaaaga tttaaaacca ggaggagcta ctggagaagc aggactaaaa
    26401 catttagagt ctttgattgg acaacgaatt ggcaatggtc agtgttatgg cttgtctgca
    26461 gaatattcag gatatctggg tggttgtggc atgggtgctg gaacaaaata tggtttaact
    26521 catgtgatag gaaatacttc tgcagcatct gatattggta ttgcctatga ttggtctgct
    26581 gttggttgga aagtgattca aaaccctaga tatgatcaat tagtagttgg tgcaattatt
    26641 aattgggcaa gaggtggaca agtgggttca tggtttgcag atggaactta tggacatact
    26701 ggcgttatcc gaggcttagc taatggtcgt atgcaaactt atgaacaaaa cacagagtta
    26761 ggtatgattt gtggaaagtt agatcgccag tattatagtg caagtgcaat ttcttccatt
    26821 gtcataccac caaaataggg aggtgattta atggcaaagt ggaatgtcat attaagtaca
    26881 acagaaccct ataattacgt ggggatgatt caagttcgac aaggcaataa gaatacagag
    26941 gttatggaag cgactatagt tgaaaatggt cttccctacg atttatcaga atgtaaggta
    27001 tattttgaat cagttgtagg tgggaaatat ccagtccaat tagaaacaaa aattgtggat
    27061 gctaaaaaag ggaaaattaa ctatattttt gataaatatt ccatgcagtg tttacatcga
    27121 caaacagcca atttcattat atttaaagga gaagacttga ttggaacaac tcaagacttc
    27181 tcttattttg tcattaatgc tgtttcaaaa acagaaggag aaatgggttc ttattggcaa
    27241 tcaatcgaag atttaattgc ggatatgacg gactttatta atgaaaataa aggcgatttt
    27301 acggactgga tgaatgaaag gaaagaagaa tttgaacgtt ggagacaaga acaggaacac
    27361 agtttccaag attggagaga aggacaagaa tcagactatt tggcatggtt tgaatcaatc
    27421 aaggatattt taaagacgat tgatccaggt ggagtcatgt tagccgaact aacggatgcg
    27481 cgagtagata ttcaaggagt tcgtcatgcg tctatttcag agcgtttgct ggcagatatg
    27541 gactatttat atcagaaatt gcgagcaacg cttttcacga ttgaatacgg ggagattgaa
    27601 gtgactgata ttttgcagga tgatctcttt tcagataatc atgaagtcga aaaagttgga
    27661 actgtagcat tcccgattga agaaggagcc ttgatcatcg caaccgttga tgatccaaag
    27721 caaaatgtgt tcactcttga gaaagttggg gtgatctaat ggctaaaact aaacgaatga
    27781 tggaaacgga tgaaaaaacg ggtgtacaac gccaattctt tccaatcaca catgcttccg
    27841 cagttcttgg gttagaagaa ataatagcag gagaagcaac agttttatct gttaatggaa
    27901 aaattggagc cgtcgtcatt actaaagaag atttgggatt agagaatgtt ctcacagaat
    27961 taccctatgc aagtgaagaa gatgacggca ttatcacggc agaaatgtat caaaaaattt
    28021 taaacagtgg agaaggtgac tacgtgttgc cagttgccac tatcgaccgt ttgggtggca
    28081 taaaagttgg tgaattattg acgattgatg agacagggaa agtctctgca gtcagacaat
    28141 ctgatgtcaa tttttcgctg gagttaaaag aaaaactcga ttcactgaaa aattatactg
    28201 ctggagaaaa catcactatt gatgaagatg gaacaattag ttctacaggt ggtagtggga
    28261 ctggtggtgt caatcagtca tatgtagatc aaaaattcca agaagctgta aatcaagcag
    28321 aaaattacac aaacgaaaga attccaaatt ttacttttga aaaaattggg gaggtataga
    28381 gaatgacaga tatcgtaaaa ataaaacaaa gcaatgtaca ggtttatcca caaactcatt
    28441 ggaatgctat agaaggcaaa ccaacaacgg tgaagggaga taaaggcgat cctggccaag
    28501 cagcaacaat taccatagga accgtttcta gtggttcaac cgcttctgtt acgaatgtag
    28561 gaacatcatc tgcagctaga tttaattttg ttttaccaaa gggagataaa ggtgatcctg
    28621 gaataaatgc cacaactaca gctgtagcta caactacagc aaatgggttg atgtcgtcca
    28681 cagataaaac taagttggat ggaattgcag ctggagcaca gaaaaatcca ggtaatgcta
    28741 caactacgac agcaggttta atgtcagcaa ctgacaaagc taaactcgat ggattagcca
    28801 atattacatt tgagaaagtg gggacggttt aatggctgat attgtgcaat taaaagaaga
    28861 cggagttgct aaatacttaa aaacgcatgt agaagctatt gatggtaaag aagcattggt
    28921 gcagacagat ggagaccaag ccattgcagg acataagaat ttttcaggtt ctgtaacaat
    28981 caataataaa cgtgttttga cgactgatga taacagatat gaagtggtaa atctggttgt
    29041 cactaacggt aatacaggga cagcaaagct ttatcgtgaa ggaaaaacag tttctatata
    29101 ttttgtggct ttaaacggaa aaagtagtgg cgggaatgat tcggttattt taactgttcc
    29161 agaaggctat cggacaccaa ttagttttga acaactggtt gggtc
//
LOCUS       DAZKPE010000032        29097 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000032 DAZKPE010000000
VERSION     DAZKPE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.032"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1029)
                     /locus_tag="ACG930_001558"
     CDS             complement(<1..1029)
                     /locus_tag="ACG930_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0518722.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1111..1800)
                     /locus_tag="ACG930_001559"
     CDS             complement(1111..1800)
                     /locus_tag="ACG930_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0518723.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1906..2274)
                     /gene="rplL"
                     /locus_tag="ACG930_001560"
     CDS             complement(1906..2274)
                     /gene="rplL"
                     /locus_tag="ACG930_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFQ0518724.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2327..2830)
                     /gene="rplJ"
                     /locus_tag="ACG930_001561"
     CDS             complement(2327..2830)
                     /gene="rplJ"
                     /locus_tag="ACG930_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFQ0518725.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3034..3161)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3240..3929)
                     /gene="rplA"
                     /locus_tag="ACG930_001562"
     CDS             complement(3240..3929)
                     /gene="rplA"
                     /locus_tag="ACG930_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFQ0518726.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4033..4455)
                     /gene="rplK"
                     /locus_tag="ACG930_001563"
     CDS             complement(4033..4455)
                     /gene="rplK"
                     /locus_tag="ACG930_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFQ0518727.1"
                     /translation="MAKKVEKVVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4798..5466
                     /gene="sdaAB"
                     /locus_tag="ACG930_001564"
     CDS             4798..5466
                     /gene="sdaAB"
                     /locus_tag="ACG930_001564"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFQ0518728.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5479..6351
                     /gene="sdaAA"
                     /locus_tag="ACG930_001565"
     CDS             5479..6351
                     /gene="sdaAA"
                     /locus_tag="ACG930_001565"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFQ0518729.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6442..7542)
                     /locus_tag="ACG930_001566"
                     /pseudo
     CDS             complement(6442..7542)
                     /locus_tag="ACG930_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7634..8521)
                     /locus_tag="ACG930_001567"
     CDS             complement(7634..8521)
                     /locus_tag="ACG930_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0518730.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8598..9143)
                     /gene="nusG"
                     /locus_tag="ACG930_001568"
     CDS             complement(8598..9143)
                     /gene="nusG"
                     /locus_tag="ACG930_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFQ0518731.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9244..9414)
                     /gene="secE"
                     /locus_tag="ACG930_001569"
     CDS             complement(9244..9414)
                     /gene="secE"
                     /locus_tag="ACG930_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFQ0518732.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9438..9590)
                     /gene="rpmG"
                     /locus_tag="ACG930_001570"
     CDS             complement(9438..9590)
                     /gene="rpmG"
                     /locus_tag="ACG930_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0518733.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9752..10396
                     /gene="cbpA"
                     /locus_tag="ACG930_001571"
     CDS             9752..10396
                     /gene="cbpA"
                     /locus_tag="ACG930_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFQ0518734.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10452..10955)
                     /locus_tag="ACG930_001572"
     CDS             complement(10452..10955)
                     /locus_tag="ACG930_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFQ0518735.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10968..11014)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11552..12517
                     /locus_tag="ACG930_001573"
     CDS             11552..12517
                     /locus_tag="ACG930_001573"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0518736.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12616..13788)
                     /locus_tag="ACG930_001574"
     CDS             complement(12616..13788)
                     /locus_tag="ACG930_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518737.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13775..14920)
                     /locus_tag="ACG930_001575"
     CDS             complement(13775..14920)
                     /locus_tag="ACG930_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518738.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14934..15866)
                     /locus_tag="ACG930_001576"
     CDS             complement(14934..15866)
                     /locus_tag="ACG930_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518739.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15983..17062
                     /locus_tag="ACG930_001577"
     CDS             15983..17062
                     /locus_tag="ACG930_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0518740.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRITRDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17059..17677
                     /locus_tag="ACG930_001578"
                     /pseudo
     CDS             17059..17677
                     /locus_tag="ACG930_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(17787..18014)
                     /locus_tag="ACG930_001579"
     CDS             complement(17787..18014)
                     /locus_tag="ACG930_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0518741.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18117..20705)
                     /locus_tag="ACG930_001580"
     CDS             complement(18117..20705)
                     /locus_tag="ACG930_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFQ0518742.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20725..21384)
                     /locus_tag="ACG930_001581"
     CDS             complement(20725..21384)
                     /locus_tag="ACG930_001581"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0518743.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21433..21936)
                     /gene="trmL"
                     /locus_tag="ACG930_001582"
     CDS             complement(21433..21936)
                     /gene="trmL"
                     /locus_tag="ACG930_001582"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFQ0518744.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22157..23023)
                     /locus_tag="ACG930_001583"
     CDS             complement(22157..23023)
                     /locus_tag="ACG930_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFQ0518745.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23132..23773
                     /locus_tag="ACG930_001584"
     CDS             23132..23773
                     /locus_tag="ACG930_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFQ0518746.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23835..25196)
                     /gene="mgtE"
                     /locus_tag="ACG930_001585"
     CDS             complement(23835..25196)
                     /gene="mgtE"
                     /locus_tag="ACG930_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFQ0518747.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25214..26113)
                     /locus_tag="ACG930_001586"
     CDS             complement(25214..26113)
                     /locus_tag="ACG930_001586"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0518748.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26115..26912)
                     /locus_tag="ACG930_001587"
     CDS             complement(26115..26912)
                     /locus_tag="ACG930_001587"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFQ0518749.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26890..27594)
                     /locus_tag="ACG930_001588"
     CDS             complement(26890..27594)
                     /locus_tag="ACG930_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFQ0518750.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27725..28300
                     /locus_tag="ACG930_001589"
     CDS             27725..28300
                     /locus_tag="ACG930_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFQ0518751.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28418..29095
                     /locus_tag="ACG930_001590"
     CDS             28418..29095
                     /locus_tag="ACG930_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFQ0518752.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8562 a         6168 c         5230 g         9137 t
ORIGIN      
        1 tacagtatta tttcggttgc ttgctgcttc acctagccct tgtactcgtg tttgattggc
       61 gacttgacca aattgattcc cgacgtctaa taaaataata gctaaaagca aaatggccaa
      121 atggcttccg ccaaccaata aagcaataaa gcttattgtt tgcataacaa gtcccatata
      181 cacgattttt ctttcagaat aagaatctgc cagtcgtccc acgataggtg cagcaactgc
      241 tccagacaaa ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat tgtaggcggg
      301 actgctgata taaaaaatca acgtagacca aaagatcgaa aatgttccaa acatgaaaaa
      361 tccactgact gccgcttctc ttaatagacg ttgagaagca actaaatgcg gcaaactttt
      421 aagtgaatca aggtatgaaa cagctgtact actttgctgg acagaacgcg gcattttcca
      481 gtaaagcaga agtgtaagaa ttccgactgc acataaagca aataaataga tcatccgcca
      541 agaaaaaaga ctggcaacaa taccagatac cgtccgagaa agcaaaatcc ccacgagtaa
      601 accgctaagc aatgtaccca tgaccttccc tcttgctttt ggtcccgcta gtaccgcacc
      661 gtaaggaatg atgatttgcg gcacgatcga aagtaatcct attaaaaaag aagcgcatgc
      721 aaataacgta aacgaaggcg caaaaaaagc ggccaacaga gagacggcag ataacgctac
      781 cattcgaatg atcaattttg gacgatccac cacgtcccct aaaggaacta aaaacagtaa
      841 ccctaacgca tagcctaatt gggtcaacat cgtcaatatc ccgactgcac ttgtgctaac
      901 agataaacta gctgctactt ttgttccaat cggctggatg taatacatat tggcaacaac
      961 aacgccacaa gtgattgata atagtaaaat aagcgaagtt gttaaaggtg ttttttcatt
     1021 actcttcatt gatttccccc atttcctatc ttagtttaca acttatggaa aagattggaa
     1081 atagaaaaat acaactattc gccacactta ttatttgtgc ttttgttttc cttgtttttt
     1141 cttgcgatct ttataaatga agacaactaa ccctactagc acagtaacac ttgcaaccaa
     1201 cgtgactgca gttttgttat atccgtgaaa cagagcttct ccaccacacg catacaacac
     1261 agacgaaggg atgactccaa tcacgatcga caatatgatt tgctgtagag gcaatttcat
     1321 cgcatctgca gcaaaattga ccatagaaga tggaataacc ggtatcatat agcctaacat
     1381 tacacctatt tttggatgtt tcatttgtcg gattgcttgc acccaatgat tcgtttcggt
     1441 tttcttatct aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt taccaagagc
     1501 attacccaaa atgttgatga tcgcacctgt cagtggtcca aagctcaaac cagcaatgac
     1561 tccaactact gaagtaggaa tacctggaac agcacacatc accgctgtca atacgatcaa
     1621 gagtatcgat gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg ccttactcgc
     1681 tctcggattt aaaaataatt ggatgtctgt ctgatattct aaatacaacc gatagcccac
     1741 taccagtatc agaatgattc ccaacgagat caacatcaat cggattattt tctttttcat
     1801 atttcctcct gaaaaaaatc tatattcatt aaataatagt ttaacataaa aacaaaaaag
     1861 caccgaaatc caacatagga tctcagtgct tttaaatagt aaaaattatt taacagttac
     1921 agatgcgcca acttcttcaa gtttagcttt caattcttca gcttcttctt tagatacgcc
     1981 ttctttaact ggtgcaggag cgccatcaac tacagcttta gcttctttca agcctaaacc
     2041 agttgcttca cgaactgctt tgataacttt aactttttgg tctccagctg cagttaattc
     2101 tacagtgaat tctgtttgtt cttcagcagc agcagcgcca ccagcagcag ctacagctac
     2161 aggagcagca gcagatacgc caaattcttc ttcaatagct ttaactaggt cgttaagttc
     2221 taggatagtt gcttctttta actcagcaac gatgttttca atgttcaatg ccattataat
     2281 ttcctccgtt taattgttct tttttattta atgctttatg cggcaattaa gctgcatctc
     2341 catcttcttt gtctgccact gctttgacag cgtaagccac gttgcggact ggcgcttgta
     2401 gtacagatag caacatagat agaagtcctt cgcgatttgg caattttgcc aatgctgtga
     2461 tttcttccaa tgaagagact ttaccttcga tgataccgcc tttgatttct aatgcttttg
     2521 cttctttagc aaattcgtcc atgattttcg ctggtgcgac tacatcttcg ttactgaatg
     2581 caacagctgt aggtccagtg aatacttcgt ccatgccttc aaggccagct tttttagctg
     2641 cacgtgaaag aatagaattt ttgataactt tcatttctac gttagcatca cgaagttgtt
     2701 tacgtaaacg tgttacttca tcaactgtta atccgcggta gtcaacgact actactgatg
     2761 cagctgctgt aaatttttcg cttacttcat caacgattgc tgcttttttt gcgataattg
     2821 cttcactcat ttttgagttt cacctcctga attttgatgg aagagttttt tgcactgaaa
     2881 aggcaagtca cttttatagt tactttgctc aaccagtatt attcatcacc tattcacttc
     2941 gttcatagtg attctactcg ctttgctcga aaggaaactc ctttcgcttt gctcaaccag
     3001 tattgttcat catctcttca cttcgttcat agtgattcac aataaaaaac tctatgccac
     3061 cgcagacata gagggactat tgaatatatt caataaacgt cctcggtagg aaattaaggc
     3121 ttgatgccac ctactgtctt cggtacaagt taattattaa cctcaactag cttagcatgc
     3181 taaactagtt gagtcaagaa ttatttttca gttggatcaa tcaacattct aatatttaat
     3241 tagaaagaag cttggtcaac atggatacca ggtccaaatg ttgttgtgat cgttacattt
     3301 ttcatgtatt gacctttagc tgctgatggt ttagctttta gcaatacatc atggattgct
     3361 gcaaagtttt caactaattt ttcatcgtca aatgaaactt ttccgattgg tacatggata
     3421 tttccagctt tgtccacacg gtaagttact ttaccagctt tcacttcgtt tactgctttt
     3481 gttacgtcca ttgtaactgt accagtttta gggtttggca ttaagccttt tggtcctaat
     3541 actcgtccta gacgacctac agtagccatc atatcaggtg ttgcaacaac tacatcaaag
     3601 tcaaaccatc cgttttggat tttttgaacc atgtcgtcgt cacctacgaa atctgcacca
     3661 gctgcttcag cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt ttgtgtttta
     3721 ccagttccgt ttggtaatac aacagcacca cggatttgtt ggtctgcttt tttagggtct
     3781 acgttcaaac ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt tgtttctttt
     3841 gctaaagcta ctgcttcggc aacaggataa actttacttg aatcaacttt ttttaatgca
     3901 tcttgcattt ttttgctctt tttagccatt ttggttcctc cttgattgtg gttataacgg
     3961 ttgtacctcc cacgtgttct atatctttca atatagagcc aactgagaag ctgctgtctt
     4021 agggtgtata gattattcta cagtgatccc catgcttcgt gcagttcctt caaccatgcg
     4081 cattgctgct tcaacgttag ctgcgtttag gtcttccatt tttaattcag cgatttctct
     4141 tacttgatcg ctagaaactt tcgcaacttt atttttgttt ggttcgcctg aacctttttc
     4201 gattttagct gcttttttca atagaacagc agctggcggt gtttttgtaa cgaatgtgaa
     4261 tgaacggtct tcgtatacag aaataacaac cggaatgatc aaacctgctt gatcagctgt
     4321 acgagcgttg aattcttttg tgaatcccat gatattgata cccgcttgac ctagtgcagg
     4381 acctactggt ggagctggag ttgctttacc tgcaggaatt tgcaatttaa cgactttttc
     4441 tactttcttt gccacgagac atacctcctt aagtccgtga tgtggttaat tggagatgca
     4501 tatttctcct cccacgtttt atctgatctg aaaaaatcca gacaaataat gtgcaaaaca
     4561 atgcacactg gtacagtata gcaaatttat ttgttttttc aagatttttt tctgctattt
     4621 ttacattttg cttgaataaa cgctaaattt attctaaaaa aacaacaatt tttcgttctc
     4681 atttcttctt ttatgttaca cttgcgctag catggttcaa cagatgaaag caaacaataa
     4741 cacggttttt tagacccttg tacaaagatt cctacataac aaaatgaggt ggagaaaatg
     4801 aaagatttaa ggtatagaag tgtctttgat attattggac ctgtgatgat tggtccaagt
     4861 agctctcaca ctgccggagc tgctagaatc gggaaaatca tacgtagtat atttggcgaa
     4921 cagcctgatt ctgtagatat ttatctatat gaatcatttg caaaaaccta tcgggggcac
     4981 ggaacagata ttgcattagt tggcggcctg ttagggatgg aacccgatga tgaacgttta
     5041 gctgattctt tgaaattggc atatgaagcc ggtatggaag tcttgtttgt tcctaagagt
     5101 gaaaaagccg aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac acgaaagctt
     5161 tcagtcactg gcatttcgat cggcggtggc aatatccaga tttctgaatt gaatggattc
     5221 aaaatttctt taagcatggg tactcctacc ttgatcgttg tccaccaaga tgttccaggt
     5281 atgattgcta aagtgactag tatactttct gagaccaata cgaatatcgg cactatgaca
     5341 gtgacacggg aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga tgatcctcaa
     5401 gtagaagaaa cggtaaaaag actcaaacag ctgccaaata tcgacagcgt aaattatttc
     5461 gattaaggag ctaaaaaaat gtttttatcg attgaagaat tagtagatca agcaaaagct
     5521 tatccaagtg tagcagaatt gatgattgca gttgaaatgg aaatgagtgg ccgttcccgt
     5581 agtcacatca tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc aatcaacgag
     5641 ggaaaagaag gtgttacctc cgtcacagga attaccggtg gtgatgcaaa aaaattagat
     5701 gattatttaa atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc tgtacgcaat
     5761 gctgtagctg ttaatgaagt caatgcaaaa atggggttga tttgtgctac accgactgcc
     5821 ggaagcgcgg gtgttgttcc tggtgtgctg atggctgtcc gagatcggct tgatttgaca
     5881 catgaacagc aattggaatt cttatttacc gctggcgctt tcgggttagt catcgcaaac
     5941 aacgcttcta tcagtggtgc agaaggggga tgtcaagcag aagttggttc tgcaagtgca
     6001 atggcagcag cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc agcacaagca
     6061 gtagccatta cattgaaaaa tatgatggga ctgatttgcg atcccgttgc aggcttagtt
     6121 gaagtcccgt gtgtcaaacg taatgcttta ggctcttctc aagcttttat ctctgctgat
     6181 atggcattag cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc tgcaatgtac
     6241 caagtcggac gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg cttagctgtt
     6301 acgccaactg ctaaacgact tgcggaagag attttaaata agagggcgtg ataaagctcc
     6361 ttaatttcga gtattaagag attagttatc ttcataacaa aaaacgaaga gaggactaat
     6421 tgcccttctc ttcgtttttt attaatccat caatttcgta ttttttactt catcgatcgt
     6481 ttttgttcct gcaagttgca tcgtgatcga caattctttg ttcaggtgtt caaaaacaga
     6541 tgttactcct tctgccccac ctagattcaa cccataaatc actggtcggc caatcgcaac
     6601 taagtcagca ccacttgcca gagctttgaa gacatgctct cctcgacgga caccagagtc
     6661 gaaaatcact ggtacacgtt tgttgactac ttcggcaatt tttggcaata cttcaaagga
     6721 cgcaggacct ccatctaatt gacgtccacc atgattggat acccagatac catctgcccc
     6781 tgcagagata gcgattactg catcttctgg cgattgtatt ccttttacga taactggaag
     6841 atgggtgatt tctttgattg ttttgatgtc atctggtgtc aagccttgtt ttgcagctgc
     6901 ataaatttct gcgattcctt ttccttcgcc attaccactt gcactttgtt cgctatacgc
     6961 agctaagtta ggcattggta atggaaattg gaattgattg atgacgtctt cttcacggta
     7021 accaccgagc gttgaatctg ccgttaaaat gatagcttta gcccctgctt ctactgcttt
     7081 gttcaaaatg aactcattga atctgtcgtc tttactcata tataattgga aaaactgcgg
     7141 tgcgcctggc gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag tgctgatgga
     7201 aaagattgat ccagcagcag ctactccttt agctgtatca gcttcccctt tttcatgtgc
     7261 caatccttgg gccgctgatg gcgcttggat aatcggtgta tctaattcaa ttccgaaaac
     7321 agatgtatgc aaatcggctg agtcgattcc gcgtaatatc cgtggcatga ttttctttgt
     7381 attaaaagaa gtcgtatttt ctttcatcgt ccactcatct tcagaaccac cgcgaatata
     7441 gccaaaagct cctgcttcca tgcgctcttt tacacgacct tctagttagg caatgtttac
     7501 aatatcgatt ggatgttctt cattacttgt atgataagtc atagtagatc cttctttcat
     7561 cttcttgatt acatataaat catactaaac ttacaaaaag taagcaaaca tttactctca
     7621 gatactttta tcgctattct ttccaaataa atcgacttac aagctgatct acttcttggt
     7681 tttcatgaag catactatga gaggcatttt cacctgtcac tactttttcc tctatttcat
     7741 ttccgcgttg cttcaacaac gcatagaccg ctaatgcact gtttaacggt actgttccat
     7801 cactcaagtc tgtttcatct agttgaccag caatcaagaa aaatcgagtg gttataggaa
     7861 tattaccgat catttgctgg taatcttgat agcggttaga aacgacagca ggcccctttg
     7921 ctaactcatc tgtcagagac tgcgcactat catcgacaaa atcattaaaa ggcgcgccaa
     7981 ttgctgttaa tgtctgaact tgtggcaatg acgtatcctg tccatacgtt cctaaatagc
     8041 gtagtgcact aactcctccc atggaatgcc ccactatgtt gactttatct atgccgtagt
     8101 tttctttcag atacaaaaga caagttttga tccattctgc ttgattccac tcgttatttt
     8161 tattatcttc aaacaatact tggaccatcg gattgtctgc ttttccagac aaatctcctg
     8221 ttgcttgtat ttgtccatct gttcctactg ttaaaaccaa ttcttttact gcttgctgat
     8281 ttttttccaa acgccgcaac atccctttaa aggaattttc tgtcccgctg tagccgtgga
     8341 aaaaaagtgt tggaatagtg gttttttcta tcactttact ggattctgcc gttttttctt
     8401 tatcagaaac ttcagtagta tttatcttcg tcgtctggca accacttaac gcaaacaaac
     8461 tgataaggac taaagctgct gcagttgcac gtttgcataa atttttgatt ggttctgtca
     8521 tacacctctt cctttccata tagaaaaaag aaagacttga aaggccaatc atatgatcga
     8581 catttcaagt ctctttatta atcgatttta tctacttgat cgaaatcaag ttctgtactg
     8641 gtttcacgtc caaacatatc gatgttgact ttcaattttt ctttttctcc gtcaacttct
     8701 gttacttgtc cttctaatcc agcaaatgcg ccttcgatga ttttcacgac ttcgccaact
     8761 tctacttcta gatcattttg tcgcaggctc ataccgatag aacgcaagat atgattgact
     8821 tcttctggaa gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac gaatcctgtc
     8881 acaccaggtg tgttgcggac aacataccat gaagcgtctg tcatgatcat ttcaacaagt
     8941 acgtatcctg ggaatgtttt atgaacgatt tctttttctt tcccattttt gacttcagtt
     9001 tctttttctt caggaacaac gacacggaaa ataaagtcgg ccattttcat actttgcgca
     9061 cgagattcga tatttgcttt tactttgttt tcatatcctg aatatgtatg caagacatac
     9121 cagttttttt caaaagattc cattgaaggc tcctcatttc attgtaaaat aaaaaaacct
     9181 cagtacaccc gaagtttttc tttcgcttca ttatagcact aaaagtacgt tgtggctagc
     9241 gagttatttt aaaatccagc caaataagct ttggatggct gtatccatta cgtaaaacat
     9301 caatccgaaa ataatagaag tttcgatgac tactaacgta tctttacgga gttgttttct
     9361 gcttggccaa gttacttgtt tgatttcatc ttttacgctt tttagaaatt tcatgagaca
     9421 acctcccttg ctactgttta tttcgtttct ttatgtaatg tatattgatt acaatattta
     9481 caaaacttat tgatttccaa acgttcgccg ctttttcctt cactgactga ttttgtgtag
     9541 ttgcgagacc cacaaacgga acaagcgagt gctgcttttt tctttgccat ttacttctgc
     9601 ccccttgctg agaatcagac ttatacttca taacagtatc acgtaacttt ttacttgtca
     9661 atttgtgaaa taaactatct attgttttgg ataaaattat gatatgatta atttgaaatt
     9721 aagctaaaat gagacaattg gaggtatagc gatgctatta aaaacacttg tatataagaa
     9781 aaaagatctg acaaccgtta cagagactag tacattagaa gaagcattaa aaattttaga
     9841 aacttccgga taccgttgtg tgccgatctt agattcttca ggtaatattt tccgtggaaa
     9901 catttacaaa atgcatatct atcgtcataa agcaaatggc ggtgatatga cgcttcctgt
     9961 cactcatctt ttgaaaaacg ctacaaagtt catttacctg gatacttctt tcttcaaagt
    10021 attctttacg atcaaagagc ttccttatat tgctgtcctt gacagtgaaa atcattttta
    10081 tggtattttg acacatagta cgttgcttaa tatgctctct caatcttgga gcgtagaaca
    10141 aggaagctat gtactgacaa ttgcttccac aggaaagcaa ggagatttgg ctgctattgc
    10201 aaaaatcatt tcaaaacaca gcagcattgc cagctgtatt actcttgata tcgaaaaaga
    10261 cgaatacatt cgacgtacat tgatcacgct accggctaac actgaagcga aagtatgtga
    10321 aacgatcgtc aaccacttag agaaaaagaa ttataaagtg gtagaaattg aaaatttgca
    10381 aaaccaagaa gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct ttcttttttc
    10441 gctttttata attagacacg cttttcaaaa tcaagcgcgc gatctaaata atacatcaat
    10501 ggtgctgaaa cagccatgac gataaactca cttaatgcaa gcgtgccata ggttgtccaa
    10561 aatgcttggc cacctgttgg aactaacata taagcaatca gtcccatgct gatggtaaag
    10621 aagatcgtgt tcaatactaa acgcatcttt acatttttca ctttgttttg caataaagct
    10681 gtcaggccta aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat gataccaaaa
    10741 ccaaagaagg cattatagac gatgaccccg cctaaaactc cccaaagcaa tttacggtta
    10801 aagacaacta aatgattcaa actttctgaa atacgaaact ggatcggccc tgaggataca
    10861 ggcgcaacta aaatagttaa cgctagataa agagccatga tgatgccatt tacaacgatt
    10921 acggataacc gttgtctgct tttcgttttt tgcattttct ctcctctttt ctcctagttt
    10981 ttttaacgcg ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa ttataacaga
    11041 cttttcattt atttcaatcc gtcttatctg cttttaaaaa agcaaaagct taaacaatgt
    11101 aaacgtttgc taaaaatcgt gggatatggt ataaagtaag tgtaaggggt cataagaatt
    11161 cccagtaaag cagacgaagt aggatctgca agaacagaat tgttgtgaaa cttaaataaa
    11221 taaaaaagga tgtgggaatt tgagcaacct cttactagag aacggtctag caagcagctg
    11281 aagatctaag tggacatgcc gaaccttgga acttctcctt acgtaagtaa tggatcatgc
    11341 gcttgctagg cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct
    11401 gctataataa ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca
    11461 ttcaaaaaat agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat
    11521 atcttgtttt attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa
    11581 tccatcggca ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa
    11641 aaataagcat attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat
    11701 tgctgaaact ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat
    11761 cgatactttc ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga
    11821 tactttctat cagatggaag tagaattccc agttgcttat attccagcag gttctggaaa
    11881 tgattttgct cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt
    11941 agcagctcaa tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa
    12001 aaaaggaata gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac
    12061 aaatcattct tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt
    12121 attctctatt ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg
    12181 aggaaaacaa ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt
    12241 tggcggagga atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt
    12301 cgtggtcgaa cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa
    12361 aaaacaattg aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc
    12421 aacaacaccg caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat
    12481 cacaataacc acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct
    12541 acatctggaa caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct
    12601 ttttttacta tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt
    12661 acccaaaata aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt
    12721 gaaccaaaaa gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt
    12781 attttgaaca aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa
    12841 gtattctgct ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt
    12901 gatcccaccg ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat
    12961 gatcggcaat aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga
    13021 ggtgtggatc actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta
    13081 actaatcaaa ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg
    13141 gtttcgttta ctgatctctt tgcgattaaa cgctagattg atgacgctga aaccgctaaa
    13201 aatggataga aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt
    13261 catccgctga ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg
    13321 tgtctgttcc atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg
    13381 caaaaaggtg ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg
    13441 tatcttgatc gtcgccatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg
    13501 taagataatg tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc
    13561 atccaatgta acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg
    13621 cgactcttct tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc
    13681 aatattttgc gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt
    13741 cgatttattt gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc
    13801 tttccatcca agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat
    13861 tggtataaaa actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca
    13921 agttgacgag atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt
    13981 gttccgaccc catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc
    14041 tatccttttg caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa
    14101 tcgcacacaa cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt
    14161 ctacttgata gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg
    14221 taaagcttgc tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca
    14281 agcgaatacc atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca
    14341 tcgtcccgta gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca
    14401 tattacgacc tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg
    14461 gcgcgagatc aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta
    14521 aaaattgatc catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga
    14581 gcgaaacaga tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt
    14641 cattcgcttc tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga
    14701 cttgttctaa gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa
    14761 ttccagtatt aatcgtttca agattgccac cttgatcaat ctcgccaaag gccgccataa
    14821 acatcaatcc taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca
    14881 gcagtatttt tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct
    14941 ctcaaatcct tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct
    15001 atttttccgt aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta
    15061 tttagttcag tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct
    15121 attgttcgct gaatcgctga caacacattt tctgggagta atgggatgtc gatcgtcaaa
    15181 cgatccgccg tccgtaccat atcttttaga gattctttgg ttcctttagc aatcacctgt
    15241 ccttgatcca tgatcacgat ctggtcgcaa agaatttcta cttcttccat gtaatgtgtt
    15301 gtatagacaa tggttgctcc ttgtcgattc agctccttga tactttctaa aattttattc
    15361 cgactttggg ggtctacagc tactgtcggc tcatctaaaa aaattaaccg cggcttgtgg
    15421 gcaatcccac atgcgatgtt caaccgacgt ttcaagccac cactaagttc tcctggacga
    15481 aacgaaacat atttttctaa tcccactaat tgaatcacct cttcaatcaa ggctttcctt
    15541 ttctcttttt cggaaacata taaaccgcaa aaataatcga tattttcttg cacacttagt
    15601 tcgtcaaaga ccgcaacgtc ttgaggaacg accccaatca ttgccttgac agcataattt
    15661 tcaggagtca ttgttgtccc gaacaattta atggttcctt tgtcataatt taacaaagaa
    15721 agcatacagt tgatggcagt cgatttccca ctgccgtttg gacctaacag acctaagact
    15781 tctccttctt gtacttgcag atcaaaatga ttcaatgcta caaaatctcc atagcgtttg
    15841 actaatttat caatttcgat aatcatcatg aaaaactcct tccaaatttc ttgttgatct
    15901 gactataata aagtgcaaga aaagaaacta gtgacgattg gctaaaccac acatgacatt
    15961 tgtcacaatg aaggagtctg ctatgcataa atctcggcta ctcaacgaaa ctagctttct
    16021 actggttatc tcattgcttt tgctggtaag tcaaggattc gttgctatgc aagttatcta
    16081 tttattgatc gccgttttat tcactggtgt cagttattta ctgcctacaa agccaaattg
    16141 gattttccaa gttattctat ttcttttatg tgccttttta cctgatcttg tcctgtttct
    16201 gccagcgacg atgcgagtga tcgcccctga agaaagccac cttgattact tgtttttgtt
    16261 aggttttttg ttgatttcga cggttggtaa tcatcccccc atcaaggtcg cctttgtcgt
    16321 aattttgctg tttttttcct tttacttacg aaaaaaagat caacgaacga ccgatcttga
    16381 gaaaaagtac attgtctcca aagatactca ttgggaaaaa caacaagagt tatcggaaca
    16441 aaataaagca ttggccctgt cacaagaaac acaattagcc ttgcaaattg tggaagaacg
    16501 gaaccgaatt acccgagaca tccatgacaa tgtcggtcat ctgctgtcaa gtgcgatttt
    16561 acaaattggt gcgcttgaaa tgatcaatca agaaccaaaa ctaaaagaac cattagaaaa
    16621 tttaagtgcc accgttcaca ctgggatgga tcggattcgt caaagtgtcc atgacctcca
    16681 tgagacatcg atctcttttc aacactcctt agagtttctg atcgctgatt ttccttcttc
    16741 tgttacgatt gaaggaaact tgtttgaagg attgaatgaa acgcagcaaa actgcttctt
    16801 aatggtcatc aaagaagcct taaccaacag tatcaaacat agtcatgcca aaaccgttgt
    16861 tttacatttt cgaacgttgc cggcctttta tcgcttgcaa atcacgaatg atggcaccag
    16921 cccacaaaaa aattctgctc ccggtattgg tttgaaaacg atgcgtcaac gtgttcaaga
    16981 acaaaaggga caagtccata ttttccaaga aaaccagcaa tttcagttaa cgatcatttt
    17041 accaagggag ggacaccaat gataacagta gtcattattg atgatgatcc atttgtgacg
    17101 aaatcgttac aaaccatttt agaaagcacg aaagagatcc gtgtgttagg cattggtcat
    17161 tgtgccaagg atgcgcgaaa cccatcgtcc cgatgttttg ctgacggaca tccgcatgcc
    17221 taaacaaacg ggcatcgatg ctgccaaaga aattttggct aaatttccca aagccatcct
    17281 tttgcttttg acgacattca aagatgaaga atacatccgc gaagcatttt ccatcggtgt
    17341 caaagggtat ttaatcaaac agaacttgca agcgattatt ccttctgtca aatccgctta
    17401 taatggacag gccgtatttg gtaatgaaat catcgagact ttcactcaaa tgatgaagaa
    17461 taaaccgacg attgatagtc atgcttatgc ttcttttagt gaacgtgagc ttgcaatcat
    17521 caaagaagta gctgccggga aaaacaataa agaaattgca gatgccttgt acttgagtga
    17581 cggcactgtt cgcaattaca tcagccaatt actagaaaag ctagatttac gggatcgcac
    17641 gcaattggct atctattttt atcagcattt gcaataagtc ttatctaaca caaaaaaacc
    17701 tgaatgatgc tccttcgcat cattcaggtt tttttcacat cttctattca attgtcccgc
    17761 aaaccatttc ctcacgattg aaagaatcaa ggattcgcag ggctgccagg attcgttgga
    17821 ttgttcggcg tgttaggcgg aaaaataggc gccttgtcta acgttttttc tagttttgat
    17881 tcttcacgat cgtctcgttc tacatcagga ctttcattca atttgaattc tttttccatc
    17941 tcatctaact ttttaaagtc attgccagat tcttttgcta atttcgctaa tttatcttcg
    18001 gtttctttag ccataaagta acgcccccct tttgatttca gcttagcata tcacactgaa
    18061 aaaacaaaag aaaacgctaa ccaacgatca tttttagcta tttctcatct ttaaaatcaa
    18121 gcattttttg ccggtataaa atcgtaggga gaactgtttt ccataccaat catcggatct
    18181 actaactggt tatcgatcac ttctgctgta agaacgaaat ctttagaaac agcaggttct
    18241 acctcttctt tcttttcttc tccaacaaat gaagaaaaca gatctggttc cactgtttcc
    18301 attacttggt ttttcgtttc attcgtccca ctgtcatctt ctacaggtag cttttctttt
    18361 acaacccgtg gctcttttgt atagttccca tcttcaaatg gatcatttcc gaccaaagaa
    18421 tcttcataag ctgctagttt ggtccggaga gtgatattca ttttatcatt atccatgatc
    18481 cttgatttca acgtagtcat ccggcttgct gattcattcg ctacacaagt gacataggct
    18541 tgctcttccc ctaacaaaat caacagttcc ttactgcgag tcactgccgt gtagagcaaa
    18601 ttacgctgaa gcatccgctg atattgatgg accatgggca aaataaccat cttgaattca
    18661 ctgccttgtg atttatggat tgagcaacaa taagaaagag tgattttatt ccattcgttt
    18721 cttttataag tgacctcatt tgcatcaaac tggataacta attcatccac tttatcttca
    18781 gaatcttttg ccaagatgat acccgtgatt tctcccatat ctccattgaa tacattcaat
    18841 tcgggagtat tgactaattg gaggactttg tctcctatcc gataaacggt gtcgttccaa
    18901 tgtacttcct tttttccagg tttccctgga ttgaatatct cctgcatcat tttatttaac
    18961 gcatcgatcc ctgcaggtcc ccgatacatt ggtgctaata cttggatatc ttgtgcacgg
    19021 aatcccttat ttttcgcttt ttccacaatt ttagagatca agggttcaat ttgataagca
    19081 tcacttcgga aataggaacg atctttttga ttctttgtga aatcttttgg cagacgtcct
    19141 tctttgatct catgggcaag aggaataata ctagaaccat caccttgccg ataaatctga
    19201 ttgagttcca ttttgggaat ttgttcgatt tccaaaagat catggagtac ttgaccagga
    19261 ccgacagagg gaagctgatc tttgtctcct actaagataa cttgcatatt cgtcggaatc
    19321 gctttgaata atgtgttagc cagccatgta tcgaccatag acatctcatc aacaatcaaa
    19381 agtccgcctt ctaattcttt cgtactgact gaaggtgttt tttcccgtcc attcagcccc
    19441 agaagacgat ggatcgtact ggcaggcaga cctgtcgttt cgttcattcg tttagctgct
    19501 cggccagttg gtgctgcaag tagaatagga aaaatttctt gggtatattt tgaaggatcc
    19561 aattccagtc cgttcaactc tgcaaaaaga ttgacgattc cgttgatcac agtagttttc
    19621 cccgtacctg gtcctcctgt taaaataaat agaggggaac ggattgcttc agcgatagct
    19681 tgttcttgcg aaggtccata ctgtatgccg aatatttttt cgatacgccg aatattcttc
    19741 tgcacttctt tttcaggata atggatttct tttttacgac tgagaaggcg ctggatcgaa
    19801 ttaccgatcc cccattcaga aaagtacaaa ctgttttcgt aaagattagt ctcttcttgt
    19861 tgtatctttc cttcttcaac aagttggata attacagtag caacctgatc aggctggatt
    19921 tcaattgggc gacttgtttc taaaatacgg atcgtttgct gaagcaatgt ctccgccggt
    19981 acgtatgtat ctcctgtttg aactgcatgc tgaaaaatct gatgcaagat agctgctcga
    20041 attcttctcg gtgaatctgc tgcaataccg atttgttcgg ctagattatc tgcacgtttg
    20101 aacccgattc cttctatgtc ttcgactagc tggtacggat tttcttcgat gatatccaaa
    20161 gactcgttct tataggcctg gtagatactg aaagctaact gactaccgaa cccgtaacga
    20221 ttcagtccca tgatcacttg atccatcccg tggtttagcc gaatcgtctc agcaagcatt
    20281 tctctttttg gcttcgtcaa accggagatt tgttttaata ccgaaggatc agcaatgatt
    20341 ttttcgatag catcttctcc cagcaattct acaatttttt ctgctgtttt cttcccgatt
    20401 cctgggaatt tttcgctgga aagatacgct acgatcccat ttgcagttgt tggcttttct
    20461 tgctcatatc tttcgagttt aagctgcctt ccgtatttag gatgatccac taattctcca
    20521 taaaaacgat aagtctcatt ttcttgaata tcgccgaaac ttccggtgac tacaatctct
    20581 ttttcacggt aatcagctgt ggtttcactg atgtgtacca aaagcacttt gtaaaaatta
    20641 ctaggatttt gaaaaaaaat cgcggcaact gtaccaacga aataaggcat ttcttctggc
    20701 tgcatcggaa gccgcctcct tcttctatag taaaggttct ggtgctgttt cagttcctaa
    20761 aaaatctgtt tggttccata ctttcagttc atatggcaat aatctgcaag gctcttcagt
    20821 ctctaaaatc gtcaaactac tattgaacaa tccacccatt tcacgcaact cacttagctc
    20881 ttttcctgtc atccattgaa tggctgcagt taaagaagct ccatgtccta cgaataaaag
    20941 tgggccatct ttatgtcggg caaccgcatc tgctacaaca gtttcgatac gtgtgattgc
    21001 cgattcaatc gtttctccgt gaaaaggaga aggatcatac agatctaaat gattacgcaa
    21061 attcggcaga ttatccggat atttctggta catttcatcg atcgactgac cttctaaagt
    21121 acccagccct agttctctta gcttatctgt ataaaaaatc tctaccggac gagcaagctc
    21181 tttgttgata ccttctgctg tatcacgtgc tcgctttgct gtactggaat aaattgcttt
    21241 aaaaggaaca tattttacct ttttcccaaa tgctttgatt tcttcgtaac tttgtggcaa
    21301 aagcggagaa tcgccattgc tcccttgaaa acgtctttcc tgattccatt gtgtcttccc
    21361 atgtcgggta aaatatagtt ccatacgcag caaactcctg tctttctttt attttactct
    21421 ataataaact gtctaatcca gcttgtcatt ttcatagtga tgcgtcaatt ctaaattagg
    21481 gaatccttgc tggcgaagtg cttcatacac tatcattgca gctgtattcg ataaattcaa
    21541 tgagcggaca tgctcatcat tcatagggat gcgtaaacac ttttcttcgt tttcacgcat
    21601 aaatgtttct ggcaaaccgg ttgtttcttt tccaaataaa aagaagtgct cttctccatc
    21661 agcaaaattt tcgtcactat atactttatg ggcaaatttt gagatcaaat gtagtttacg
    21721 attacctaaa aatgttaaaa aagcttctaa attactgtgg taagtaatat ttacatcatt
    21781 ccaataatcc aaccctgccc gttttagatg tttgtcatca gttgaaaaac ctagtggctc
    21841 gattaaatga agcggagtat tcgtggctgc acacgtacgg gcaatatttc cagtgtttgc
    21901 agggattaat ggttcaaata aaacgatatg attcatcagg atcattcctc tcatatttat
    21961 gttcgtttct attttctgac aatttgattt ttgcataaaa aaaaacgtat caactcggtg
    22021 tcagtcactg cgagtcgtta cgttagtgaa gctcttctca ctaactttta tcagaacagg
    22081 aacctgataa aaaccaatga aaaaacaact tgttgctaat ataacaccct caactttttt
    22141 ttgcaacctc tactcattaa aaactgctag aaaaacgttt tctcttagtt ccttttaata
    22201 attctatgtc aattgtaatc ttcttcaaag gattcttata taagtctgct ttgattcgct
    22261 cttctacctg ccattctaaa ggtgacatgg ccaaaagatc tttttgattt tcctctggta
    22321 tctcaaattc ataggttaca cgctgacgtt cagttaattt cattgcttca gcaaacttgg
    22381 ctactacacg ttcattggaa taactctgtt tttcaggttg attcggataa aaagcctgac
    22441 gtagttcctt taaataattt tcttgtggca ccaccttcaa cacttctcca tcttctgaga
    22501 gtacacgttg gaattcttgg taatgagaag gcgaaaagat atttaaaacc gcgttgaatg
    22561 tttgatcagc aaacggcaaa ttggtcaaat cagctacaca ccaaaatgct tcggcagatt
    22621 gttctgtagc tgcgtagact ccttcttttg aaatatcaaa tccaacagca ttttgaatct
    22681 ttttcaattt tgaaagttca ttcaagaagc taccttctcc gcagccaaca tctaatagcg
    22741 agacttcttc aggtaaatgc tgcgcaatag tctcaataac gggctgatac atgccagatt
    22801 ggatcattct acgccttgga acgaacattc cttgatcgta ttctgtttta accgcatggg
    22861 ataaaaaata aagtgttcct tttttggaaa ggtcaaaacg gtgattattt ttgcatatca
    22921 agccattatc agactttttt acttcttctt ggcaaaccgg acagcggaac agctgatgat
    22981 tttctgccaa aaactggcgt cctcggtcaa ttttttttaa catagttccc cctcatttct
    23041 gttttatctt accgttagat gctcactttg gcaactgcta aaaatatgat acaatgccta
    23101 gaagaaagtg aaagataaag gagaagatta gatgatcaaa gaattttgcg ctgaaaacta
    23161 cacatctatt cctctagcaa ttgctagagg agccgatcgg atcgaattgt gtgacaactt
    23221 agcggtcggt ggcacaaccc cgagtactgg tgtgatcgaa gaaacgttaa gttatgctgg
    23281 ggaaaaagat atccccgtaa tgacgattat tcgtcctaga gggggcgact tcgtctataa
    23341 cgatatcgaa ttgaaaatca tgcatactga tttgattgaa gcaaagaaat tagggacgga
    23401 tggcgtagta tttggttgtc ttactccttc aggctggcta gacgaagagg ccttagaact
    23461 attgatcgaa acagcagaag ggttgcagat caccttccat atggcttttg acagtattcc
    23521 tgaagatcgg caattcgaag caatcgattg gctggtagaa catggtgttg accgtatctt
    23581 gactcatggc ggtcctgctg acaaaactat tgtagaaaat ttcccacggc ttaaagaatt
    23641 gattgcctat acagatggcc gcttaatcat tttgcctggt ggtggtgtca ctgcagagaa
    23701 tgcagcacat gtagctaaag aattgaacgt aagcgaagta cacggaacca aaatcgtgga
    23761 tcttcagtta taatcttata aacaaaaaaa catttgcaac aggcataatg cttattgcaa
    23821 atgtttttgt ttttttacat aaaatagccc ataaataaag aagcaatatt gaaataaatc
    23881 agtacactcg tcaaatcgct caaagtcgtg ataaagggac cgcttgctac tgctggatca
    23941 aatcctagac gatccattag catcgggatt aaactacctg caagattcgc cactgtgatt
    24001 gcaaatagca tagccatccc tatgacaaac cccaagataa aattatgttt ccaaaaacct
    24061 acgattagaa aaatcgtgat ccccgtaaca gctcctgtga caacgccggt caagacttca
    24121 gccaaaacaa gtcgaacaaa tccatgatct ttctcatcag aaatcgcaag tcgacgaaca
    24181 gccacagcta gcgactgggt tccagcatta ccggcagttc ctgtaatcag cgaaatgaag
    24241 actgctaaaa tactcgcttc acttaccaag tcttcatagt gactgattaa agaagcggtc
    24301 gacataccta aaaacaacag agtgatcagc caaggcaaac gtcgagacgc tgcctttact
    24361 ggattttcat taatttcttc cacattgacc ccggcaagtc ctgaataatc gctagcagct
    24421 tcatcatcaa taacgtcgat gatatcatcg actgtgacga ttcctaacaa atgatcatca
    24481 taatcggtaa caggaagagc taagaagtca taatctctaa atgtttgtgc cacatcttct
    24541 tggtcgtcgc ctacatgaac tgaaagcact cgttcgctca tcagatcaga aatcattgcg
    24601 tcgtcatcat tcacgattag gtcgcgcaga gaaataaccc ctactagctg accttcttga
    24661 ttaacgacat agatgtaata gattgtttca gctacatctg cttcgttctt cagcacgtac
    24721 atcgcagagc gaacagtttg attggctacg atcgaaacaa attcagttgt catgatcgcg
    24781 ccagccgttt catcctcgta atggagaagt tccttgattt cactggcatc gtctgccgac
    24841 atcaaactta aatatttagc aatttgcttt ttatccagcg tattaagcaa gtcaacagca
    24901 ttatctgtat acatctcaga aagcatatca gctgcatagc taggacgcat ttcatctagg
    24961 tattctttca tatgttcgtt gtcttcttca atcacatcga acatatccgc taattcttta
    25021 ggcgacagat aggaatagat cagctgcctg ttctcttctg taagagattg gtagaattgc
    25081 ccctgctcat agatatgcat ctctaaaaaa ctgtttctga atgcctgaat attattttcc
    25141 cttaaatctt gagtcaactg ggcaaatctt tcctctaatt cttgattttc atccaaacca
    25201 atctcacctc gccttattct tcaaaccgtc tcacaactgc ctccatgtct gcggctaaag
    25261 gctgcttgaa ctccagcaac tcttctgtaa atggatggta aaaacgcaga tcataacaat
    25321 gaagggcttg tctttttatt cccagatcca ttcgcccgcc atacatatca tcaccgagca
    25381 gggcacagcc aattgcggaa aaatgaactc ttatttgatg tgtccttcct gtatgcagct
    25441 ggatatcaac taacgcgatt tctgttagtc gcttctctat ccagtactca gtctgtgccg
    25501 aacgtccttc atcagagacc attcgcttca atagcgaaga ataatctcgg gcgatcggca
    25561 aatcgatatg tccatgtgcc gataaatctg aaagccttcc actgactaag gcctgatatt
    25621 ttttcacaaa cttcttttca cgaagttgca tatctaattt tgcgtgcgca aatccatgct
    25681 ttgcaaaaag catcaagcca gatgtatccc gatctagtcg cgtcaccaca tggattactt
    25741 ggttttcgta accttgtttt ttataataag cctttacacg attagccatt gtcccatttg
    25801 gatggtattg ggcaggaata gacgaaacgc ctgctggttt atttactacc agaacgtgtt
    25861 catcttcata cacgatatcg atcggtgttt catccaaaag tacggtttca tgttctcctt
    25921 cagcaggaat cacaatggtt accttatcat ccttagctag agaaaacaag acattttcta
    25981 cttgatcatt aactttgatt tgaccgcctt gaaattttat tttcgctaac agaccctttg
    26041 agatcccttt ttcttttaaa aaatatttta cttgctgaga atgatctttc tcataatccc
    26101 atgtaaactg catatcaatc ctcactaata aaggcatctt tcacacgatg ccaaaaatgc
    26161 atatgtcgat aagaagcaaa atggatccgt tcttctgcta ttcgataata aattgagcgg
    26221 atatttgctt ttgcgacatt caattgatca accgttacaa gataatcttc tgtattttcc
    26281 aattttattt ctagccattc atcatgggca atcacgatcg gagaacccaa agtacgaaac
    26341 actcgattat tcagtgaagc aatctctgcc aactgaaagg cattgatact aggatggatc
    26401 acagcaccgc cgacactttt attatatgct gtcgaaccag taggcgtaga aatcgtcaat
    26461 ccatctcctc taaaactttc aaacagctcg tttttgatgt atacatcggc taccatcgta
    26521 cgattggccc gtttaatcgt tgattcattc agtgctaaaa aatgctggtc cggtgtttca
    26581 tccaaataac tgatccgaac atccagcaag ggataactaa cactttgttc ccggttcgtt
    26641 cgtaagctgt ctactagttc ttccagctcg taatcccgcc aatccgtgta aaaccctaaa
    26701 tgacctgtat gcacgcccaa gaaacgcaca tcattcagac aatgactgta gtgatggaac
    26761 gccgacaata atgtgccgtc tccgccgact gagatgacca attctggctc atgatcatct
    26821 cgttgaatcc ctgcttgttc taaaagtgcg ttcaaacgtt ctgtcacttc tatagtcttt
    26881 gcttctttat tatgaacgat cgctactttc atcccctgcc tcctctcttt cgctttcttt
    26941 cttcaaaagc gttcgatagt agacatcatc tgattttcct cttccatggg agaataaccg
    27001 ctgtgcttct tggatttctt cacggatact ggacatctct tcatccaact gataggcagc
    27061 ttctgccgca cgctgaagtc gttcactcat ttcttctgga aaaacgcctt gatatttata
    27121 attcagcgaa tgctcaatcg ttgcccagaa attcatcgca agagtccgaa tctggatttc
    27181 cgccaaaatt ttcttctcac cgctgatcag ctgtacagga tactcgatca ccagatgata
    27241 agaacggtag ccacttgctt ttttatttgt gatgtaatct cgttcttgga gaactttcat
    27301 gtcttttctt ttacggatga tctcaacaac ttgatggata tcttctacaa actgacacat
    27361 gatccttaac ccggcaatat cagacatttc ttcttctaaa cgtcccattg gaatatgccg
    27421 taattgtgat tttgttacaa tactatcgac tggcttgact ctcccagtga caaattcaat
    27481 cgggacatgt cgattttgtt cacggaactg tttgcggatc ccccgcagtt tcactttcaa
    27541 ttctgataca gtttgttcat atggtgctaa aaatgcttcc caatctcgtt ccatagctga
    27601 tacctctact tcattaacat tcattgttta ttctaccata tatgcaaagt tttttcgtac
    27661 tcttgattta tgcattgacc aaaaaaagaa aattaggcaa aatagacaaa aaggagtcga
    27721 tcaaatgaca caaatgcttg aaatcgaata taaatctatg ctgacaaagc aagagtacga
    27781 gatattcatc gctcactatc aattaacaga taaagatttc cgtgtacaga ctaatattta
    27841 tttcgatacc gttgatgaac agctgaagaa acaaaattgt ggcctacgga tccgtttcgt
    27901 tggtcatcaa gctgaatata cattaaaaac acctgctgaa aaagggcgtc tcgaaacaac
    27961 ggataccttt ataacagaag aagcagaagc atttatcttc gaaaaacgtc tgcctcgttc
    28021 aggcgcagtt tttcaaaaac tttctgattt gaatatcgat cctgcttcat taatccaaac
    28081 cggaaagctt acaacaaaac gagctgaatt ccctattgaa gaaggacttt tagctattga
    28141 tgaaagctgg ggagacaatc tacacgattt tgaactggaa ctagaggtag gggatgcatc
    28201 tgtgggaaaa attgctttta taaatttttt aaaacgtttt tctttacctt atcgtcctgc
    28261 taagaacaag atccaacgta tgcttgaagc taaaaattag aaacctttca ttttcacaag
    28321 gcacttgagt tcattttttt acttttttct gttaagttat aggatgtgaa agaatctagt
    28381 cactagttgt atagaatcta ttttggggga gattcatatg atcgaaatct atttatttgt
    28441 taatccttta ggggaatact gtttcgaaat ggaacaacag ttattacaat ttatcgaaga
    28501 agagtacggg acaccatcaa aagaaaagat gcaatttcgc tttcttcctt tggtcaattt
    28561 gcagacaatt ggggatgtca tgcaacaaaa aggaatttct cagaacaatc ttgaggaacg
    28621 taatcactta ttctcaatga cttattctgc agcattggac tgcaaagcgg cgcagtttca
    28681 aggaaagaaa aaaggccgcc gttttttgat caaattgcaa gaagcagtcg gctgtaatga
    28741 cataccatat tctcaagaac ttgctgaatc catatttgaa gaaatcggcg gcgatttgaa
    28801 tatgtttaaa gaagatcgtc agtctgactt cgttaaagaa gtattctttt ctgatcaaaa
    28861 aattgctcgg gaaatgggca tcacaaaaca cccttctgca gtcgtttaca attatgcctg
    28921 cgaccgtgat tttggtgttt tagtagaagt aaaaggtaca agtagccttt ggagaatcac
    28981 agagctgtgt aaaacaacag ataactcata tcaagttttt aatggtgaac atttacatac
    29041 aaatgattct cagttccatt caagaactag ccatttacac ttgctttcta attaaaa
//
LOCUS       DAZKPE010000033        28621 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000033 DAZKPE010000000
VERSION     DAZKPE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.033"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            150..1190
                     /locus_tag="ACG930_001591"
     CDS             150..1190
                     /locus_tag="ACG930_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0518753.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            2037..2369
                     /gene="traE"
                     /locus_tag="ACG930_001592"
     CDS             2037..2369
                     /gene="traE"
                     /locus_tag="ACG930_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFQ0518754.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            2988..3329
                     /locus_tag="ACG930_001593"
     CDS             2988..3329
                     /locus_tag="ACG930_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFQ0518755.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNEWFKMTLTNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            3443..3682
                     /locus_tag="ACG930_001594"
     CDS             3443..3682
                     /locus_tag="ACG930_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518756.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            3794..3988
                     /locus_tag="ACG930_001595"
     CDS             3794..3988
                     /locus_tag="ACG930_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518757.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            4074..4745
                     /locus_tag="ACG930_001596"
     CDS             4074..4745
                     /locus_tag="ACG930_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFQ0518758.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            4798..6774
                     /locus_tag="ACG930_001597"
     CDS             4798..6774
                     /locus_tag="ACG930_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0518759.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            6789..7541
                     /locus_tag="ACG930_001598"
     CDS             6789..7541
                     /locus_tag="ACG930_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0518760.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            7557..8312
                     /locus_tag="ACG930_001599"
     CDS             7557..8312
                     /locus_tag="ACG930_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFQ0518761.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNGETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            8325..8585
                     /locus_tag="ACG930_001600"
     CDS             8325..8585
                     /locus_tag="ACG930_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518762.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            8582..10672
                     /locus_tag="ACG930_001601"
     CDS             8582..10672
                     /locus_tag="ACG930_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFQ0518763.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            10699..11163
                     /locus_tag="ACG930_001602"
     CDS             10699..11163
                     /locus_tag="ACG930_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518764.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            11160..11402
                     /locus_tag="ACG930_001603"
     CDS             11160..11402
                     /locus_tag="ACG930_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFQ0518765.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            11420..11722
                     /locus_tag="ACG930_001604"
     CDS             11420..11722
                     /locus_tag="ACG930_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518766.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            11792..13855
                     /locus_tag="ACG930_001605"
     CDS             11792..13855
                     /locus_tag="ACG930_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518767.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            13855..16467
                     /locus_tag="ACG930_001606"
     CDS             13855..16467
                     /locus_tag="ACG930_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFQ0518768.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNM
                     HDQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVI
                     RKRLLLEAEKAVKE"
     gene            16464..18995
                     /locus_tag="ACG930_001607"
     CDS             16464..18995
                     /locus_tag="ACG930_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0518769.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PEQAKGMAGNDKSGLSDIQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            19045..19377
                     /locus_tag="ACG930_001608"
     CDS             19045..19377
                     /locus_tag="ACG930_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518770.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19378..19971
                     /locus_tag="ACG930_001609"
     CDS             19378..19971
                     /locus_tag="ACG930_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518771.1"
                     /translation="MRVKGQNLVDKKSIFQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            20134..22158
                     /locus_tag="ACG930_001610"
     CDS             20134..22158
                     /locus_tag="ACG930_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFQ0518772.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            22158..23357
                     /locus_tag="ACG930_001611"
     CDS             22158..23357
                     /locus_tag="ACG930_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFQ0518773.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            23373..24017
                     /locus_tag="ACG930_001612"
     CDS             23373..24017
                     /locus_tag="ACG930_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518774.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            24028..24834
                     /locus_tag="ACG930_001613"
     CDS             24028..24834
                     /locus_tag="ACG930_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518775.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            24856..25086
                     /locus_tag="ACG930_001614"
     CDS             24856..25086
                     /locus_tag="ACG930_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518776.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            25600..25908
                     /locus_tag="ACG930_001615"
     CDS             25600..25908
                     /locus_tag="ACG930_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518777.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            25910..26332
                     /locus_tag="ACG930_001616"
     CDS             25910..26332
                     /locus_tag="ACG930_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518778.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            26352..27941
                     /gene="mobP2"
                     /locus_tag="ACG930_001617"
     CDS             26352..27941
                     /gene="mobP2"
                     /locus_tag="ACG930_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFQ0518779.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            27953..28288
                     /locus_tag="ACG930_001618"
     CDS             27953..28288
                     /locus_tag="ACG930_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518780.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            28434..>28621
                     /locus_tag="ACG930_001619"
     CDS             28434..>28621
                     /locus_tag="ACG930_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518781.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        10678 a         4396 c         5803 g         7744 t
ORIGIN      
        1 agtacataat tcattttatt tctgatttta ggtagtattt aattaaaaaa cagttttaat
       61 gcgtttgcat tttttattta tctttgctat tttcgaaaag agtaggtaat tttacataaa
      121 taaaacaatg tgaaagtaga ggatctacaa tgactgattt taattttttt aaggcggata
      181 gagtttacaa cgaattattt tatcaatttc caaaagtctt tattgtttct gacgaataca
      241 aaaaaatgaa agattcaact aagattgcct atatgctttt aaaagcaaga ttagagatcg
      301 caatcagcaa acggcaaatc gatgaagaag gtaatgttta ttttacttat acgacaaatg
      361 aactatgtag cgtattaaac tgccaaaaac aaaaagcgat agcaatcaaa aaagagttgg
      421 aatcctttgg tttattatta caaaagcaga tgggatttaa caaacagtta gggaaaaata
      481 atcctaatag actatatcta gcagaattaa aagtctcaga aaatgatatc tacttactcg
      541 aaaaatttga tagagagaat agggaaaacg ttgataaatc agagggtatg aaaatcatac
      601 ccaccctcga cgaaaaatca gacgctgaat cccttggggc tcaagagggt atgaaaatca
      661 taccgtgcca aaacgttgat aaatcagagg gtatgaaaat cataccagaa cttaataata
      721 atatattaga cactaataga cacaatatag acactgaaaa agaccgccta caagatcaat
      781 tgttgttaga caattttgag acaattatga caaacgacag cattgctacg tttatccctg
      841 aacgagtatt aaatttaata aaaacatttt cttcaagtta cagtgaagct caaaaaactg
      901 tccagactat tcataatgca aagaaaaaag ccgaaacaga aagtggtatt tcaataattt
      961 ttgaagaact cgatagttat tatgtcaatg cagaacaaga attatacacg acactgttaa
     1021 aagcctatca aaaattaaaa accgaaaaag ttgaaaatat ccagaacctg atttttgtct
     1081 atgtaaaaaa ttggtttatc gaaaaaccaa tagctgctaa agtatcaagt gaaaaacgtt
     1141 tgaattctga aagcttccca aaaactatta cgaaagactg gttagagtga aatttcactg
     1201 acaaattgat tgttgcttca tggagtagca ttaaaattaa aaatttttta ttattctaat
     1261 tatattacaa atgttacaaa gaaatagcta ttttaataga atttatgagt taaaatatta
     1321 tgataaaaat cacaaacgta gctttttacg tcataagtgt taatagttaa taattaattt
     1381 ccaacacaaa aaagagaaca aacgtttgca tgttgctgtt ttttagttat aataatacgc
     1441 gaagagaggt aatttcattt tttaaaaaag ctaaaaacct tgatattact tcttttcagg
     1501 caatacgaat attattcgct tacatttttt tgtataaatt tagttgtttt aaatttaatt
     1561 gtctgctacg cttgtgatga attaattttc gttctgcact tttggacgat aaatttggac
     1621 aattgaaaat acaaaaaaaa gaaaggccct gtgagactcg gaaggctggt aaccttcgtc
     1681 gacgtccaca ggtggcatta agacaacctt taatccctta atgcgtttac ctttcagtgt
     1741 tacggtatta cccgcaacgg atttagtata acagatattc aaaagtgata ccactttttt
     1801 tggctgtgtt aaggttaaaa atacgtgata ttacgatgaa tctatgccta agcataatgt
     1861 tataaaaatg tccgtgtggc tctttgccgt atgacgaacg ctgaaattag agggaacgca
     1921 tgtttggatg cgttccctct tttttgtttg tcatgaacga aaatcaattc tctatttttg
     1981 aaaaataaca agaaaaactt attaaaaata tttaaagtaa gtgggtggat tattttatgt
     2041 catatacagg aattttgagt ctcgaagata tttgtcacta cggtaaacgg tgtaccgcta
     2101 cagagaaaat cacgaagaaa ctatcaactg gccaaagtaa aaccgttgtg cagtgtaaga
     2161 aatatataat ccagaaagac aaagtctcag aggaaatgat ttattacgct ggtaaacaaa
     2221 aacaaataat tttaaaagat cctatccctt taaaagaact atatccaaca atcaaacatg
     2281 tttatgacca aaacggtgta ctgattggtc gaagaaaaaa tggagtcttg cgttgtaccg
     2341 caaaagggat ggggcgttta atcagctgaa ttgatcattc tcataacttg tattttatcg
     2401 tttttcgctt gcttgaaaat attgtcgaga cttctaaaag aacttagaat tactagaaaa
     2461 ataaggagta gacttgatct atcaacaatt cctttcgggg ggtgacgggg taggttttta
     2521 cgattggtaa cgtaaaaaat tggtcaatcg agtaaatgcc cttgtttgga tagtggtgaa
     2581 atgaatttgt gtaaataata tgcacagagt aaacaagagg gaatttagaa gttagacaag
     2641 ttagaatagc gcctagatta atcatgagca gctactaagg gatctaggct ttgacgcaaa
     2701 ctcatggaat aaggagtagg tcttctcgta atggggagga cgcacaagaa attgtgtcgt
     2761 gtgctgcagt acatgtagat acttgcgagg acgttggtca ttggatcaat cgagcattta
     2821 ccgatttcta ctagggtttc tcgtttcgga cgccataaac gagtcgatat tttttatgta
     2881 tttttaagta aacgaaaaac gataaaatat gaacgagtcc tgaataaagt gaaaaaattg
     2941 atataaaaca tagagaaaat gaaatttacg taatggagga atgacaaatg aaaaattatg
     3001 atccgaatat acgattgggc acacatacta ttaaggtttc tttccaacgt tgggattaca
     3061 aaggatttgt gacgtttaga agaggcggaa attgtaaagg attagatgtt ttagcattag
     3121 acgaggatga tttatactat caaaaattga ctgataatcc aattggattc ggcttgctac
     3181 ctgaagatga tgaaggtaat gaatggttta aaatgacgct tacgaatgat aatggagacg
     3241 aattatctgt tgaagatact tggtcatatt tgagtgatta tattgtcagc gttgaaatca
     3301 ttgaatttgt agcggataaa gaagaataaa aactggagga ataaatttta cagataaagg
     3361 cttagaagaa gtcacgacga ataataaaaa ggtagtatta ccttaggcat tgagtaagga
     3421 attcatttag gaggaaaatt agatggcgcg accagtttta gaggcgatgg atatggatac
     3481 tttgacaaaa ggaaggtatg tacagctgtt agctcgtggt tattcaccta aagatgtatt
     3541 caaatccctg tctaaaggaa cagatatgga aaaagaaaga ttacgaaaag aattcgatta
     3601 ttggagaacc cataatggaa tcaaggattt gaaaccagca cggccagtaa ttaaacgaaa
     3661 gaaaaagata acccaagact gaagtgtaga gcgtatgtga tcataggctt ttttattttt
     3721 gcaaaaaaca aggaaggtag gaaaactcat gaattatgaa gaaatcgaaa acagaaaaaa
     3781 agtgtcgaaa taaatggaag aaaagttgct aaaaacgatg aaacaaaaac accttaaaag
     3841 attatctgtc atgcaatata tcaatgatat gcagataaca ggaaaagaga aagcttgttt
     3901 gttaggttca atgaaaaact ttgaacagtt gagacgaact tatgtgaaaa caagttctaa
     3961 ttgtcaacta ttgttagaag tctcatgaca ttcattaata gaattcattt ttaaaacttt
     4021 ttctatggaa atgagaaaaa gattttttgt tttgtctgaa agggggtagc tggatgagaa
     4081 aatggttatt tggtttttta ggagtcgctt taatcgtctt ttgcagtgtg tttggctatg
     4141 ttagctacca aaaacatgaa ggagaggtgt ttaagcaaaa tatagaaaaa aagatgcccg
     4201 tagatcaaat caatgcacat gcaaagagtt ataaggagga tgcaacgaac gtcaataatg
     4261 atatgtcttt ggggcaaatg ttgtccatac aacaagaagc aatcgaaatg ggcgtcaata
     4321 aacaagtatt tgcacaaatt cagattcctg cacttggttt agcattgcca atttttaaag
     4381 gggcaaatca atacactttg agtcttggag cggctactta tttttatgaa gatgctgaaa
     4441 tgggcaaagg aaactatgtc ctagcaggtc ataacatgga aatgccaggt gttttatttt
     4501 ctgatattca aaagttgtca ttaggggagg tgatggactt agttagtaac gatggcgtct
     4561 atcgttacaa ggtaacgcgt aaatttatcg tacctgagta ctttaaatta atcgatggcg
     4621 ttcctgaaga gaactctttc ttgtctttgc caaagaaagg agagaaaccc ttattaacgt
     4681 tgtttacttg tgtttatacg tcacaaggaa aagaaagata cgtggtacag ggagaactac
     4741 aataacaagg ttttaatcaa cgtgagtcgt tgaaatatga aatgaggaga gtaaaaaatg
     4801 gcaataaatc ggtatgtaaa aaaagctgga atgcttattg gaatgttagg aatcattgca
     4861 ggctgctttc agggatatcg agcatatgca gaagatgtca cgcaaaaaac gccaccagag
     4921 aaggtcaata tcacggttca taaattaatg tacgatcaag gaacgcaatt gaatgttgat
     4981 attgacggga tcaaaaacga tggttatacg cacgatcaat atcctacagg tgtaacgaaa
     5041 tacaacaagg cagattatgg tgatgttgag tttacgttag gaaatattac ggatcaagta
     5101 ttaccgactg aagattctga tctaaccaac gcgaaggtgg acgaaatcgt taaagatgta
     5161 gaagacaagg gatctaacag tgagtacgtc aagaatgcaa ccaacaaaat tacttcagct
     5221 gtagatgaaa atggtgagat cacttttgct gatcaaccag cctatgtcaa ttccaaaggg
     5281 aatgtatatg tggtttatga aagtaaatcc gctgctggat tagtcacaca aaaagcaaaa
     5341 ccaatggttg tgattgcgcc aatgactgat aatacaggtt caggtttttt aaaagacatt
     5401 cacttatatc ctaaaaatat tgtttctaag ttgagttttg aattaacgaa atttggtgac
     5461 gatggcacag ctcaaagcaa acaaacacct ttaaaagggg caaaatttga gttatacaag
     5521 ggcgaacctg gaaaaggaac aaaattagga gatcttgtat cggatgatca aggaaagctg
     5581 actgctactg atttgacgtt aggaaaatac tattttgtgg aagttccttc agaagttgta
     5641 gtgggatcag ataaagaacc aacagccgat caatatttat taggcgcaga cgctcgcaac
     5701 gatgcgcaca ataaattaac ctttgaaatt acgaatgatg gcgtgacaag tgacttaaaa
     5761 gcttcatacg taaactataa agcaccagtg atcgataaaa cagtaacaaa tggaacagga
     5821 caagaacatt ctttccaaat tggtgacgca gtaaattatc aaggaacgat tcatatccca
     5881 acagacattg caggcggagc agacggtatc acagtaaacg gagtgaaaag cgaaacttct
     5941 ccttacagtg tatttaaatg gggggataca gcaggacaag gactttctta tgtcgctgct
     6001 aaagcaaata tcaaagtaac aaataaagat ggatctgtgg tattaaaaga aaatacagat
     6061 tataaaatcc aaaattcaga aaatggcttt gtgatcgatt ttatcgtgaa taatggccaa
     6121 gtaagtgata ctgtagcaag tttacacgga caagatcttc aaatgactta taacatgtat
     6181 gtaaatgaca gcgcagctgt tgccaatcca ttaacaaata gcgtggattt cgtttataac
     6241 aacaatccat ttaatcagga agaacaccac gaaaaaacga aagctgacgt tgtgacttat
     6301 ggtgcaaaat tcttaaaagt cgatagcgga ctatttggaa caggaatcaa agcaacaccg
     6361 cttgaaggcg cagaatttgc tgctaaaaac gcagaaggaa aatattatgg tggattagtt
     6421 gatacggata aagacggtgt caaagaagca gtatgggtag acgatgtagc aaatgcagcg
     6481 atcctaaaat cagataaaga aggtcacttt gaaatcactg gtttaactga aggtgaatat
     6541 tcactggaag aaacaaaagc gcctgaaaac tatcaaaaat taacgaaaga gatctctttc
     6601 aaagtagaca aagattcata caaagaagaa aaccgaatca cgatcaaaaa caatcaaaaa
     6661 gcttccgtac caatgaccgg tagcaacggt tttcaaacgt atgtattaat ctcttgcttg
     6721 ttgctaggag caggggcact ttctgcagtt gtttacttta agaagaaagc ctagaaggat
     6781 caaaaccaat gattatcagg aagcctaaga aaaagcgaat catgggtaaa tggatcattg
     6841 ctttctggtt actttcagct gtaggtgtct tacttttgat gcctgctgaa gcgagcgtgg
     6901 cgaaatacca acaaaatcag cagattgccg caatcgatcg aacaggaacg gcagcagaaa
     6961 cggattcttc tttggatgtt gctaagattg agttaggcga tcctgttggt attcttacaa
     7021 ttctaagtat ttctttaaaa ctaccaattt atgacggaac gtccgacaaa attttagaaa
     7081 atggtgtagg tattacggaa ggaactggtg atattacagg aggaaacggt aaaaatcctt
     7141 taatcgcagg tcatagtgga ctttataaag ataatctttt tgatgattta ccttcagtaa
     7201 aaaagggaga aaagttttat atcaaagttg atggtgagca gcacgcttat caaatcgatc
     7261 ggattgagga agtgcaaaaa gacgaactac aaagaaactt tgtcacttac ttagaatcaa
     7321 atcccaatga agatcgagta acgctaatga catgtacgcc taaggggatc aacacacacc
     7381 gttttctagt gtatgggaag cgagtaacct ttacaaaatc agaattaaaa gatgaagaaa
     7441 ataagaaaca aaaattatct tggaaatggc ttttaggaag tactgttttt ctttcagtca
     7501 tgatcattgg ttcgctattt gtttataaaa agaaaaaata aaggagggta accaacatga
     7561 gaaatagaaa atggctattt gtttgtgcag ccgctctttt ttctttcact gcctacacac
     7621 agttgacgtt tgcagacaga caagaaagca cggatagcac agaacaaaca atccaaacgt
     7681 cagatagcag cacgattcaa agcagcgatg aaaccgtcga ttcgtcaaca gttgattctt
     7741 cagaagaacc taaaattgct gaagacgatc aaatagtcaa acagaccatt cacgttcaaa
     7801 agattatttc ttcagaacaa ttagacaacc aggggcatga aaaacaagaa ggagtaaatg
     7861 gcgcgaagtt ttctgtttat gatgtatcgg acattttaca aaagatggat gttaaggatc
     7921 tcactactga ccaaattgaa tcccaattaa aaaatcgagt gaaaaaacta tccagtgatc
     7981 aattgaagct agtttctaat ggagaaacaa agacaattga tcaacaaaca ggtgtctttg
     8041 aattctcggt agaagtacag gcaaatcaga aacaagctta ttatattgtc aatgaatcaa
     8101 gtcctgaaaa catttctaat agcgaggata ttttgctatt aacacctgtt tctgataaaa
     8161 acggtgaatt cttaaaggat gtgtggatct atcctaaatc agaagcttcg caacctaaag
     8221 aagaagtaaa aaaaatcgtt tctactggcg taaagaaaaa cttctttgag aattgttggg
     8281 attttgttac tcacttgttt tctagagatt aaggaagaaa taaaatgaaa ctgatcaaat
     8341 tattattatt caatttttct tgtttaaccg cagtcttttt gtactgcggt ttattatttt
     8401 ctaaactatc tattttgcca agctaccaac tatacctaat gaggatttta aacataccag
     8461 ctgcttccat gccgctagat attatggaaa agctcattag gaatccatta tttactacga
     8521 tcaatttgat cgttattgtc ggaatttcac tagtcattta taaaaaagag gggatgaagg
     8581 gatgaatttt aaacactcgt ggacaagacg gttaaaatat gtttttccca taatgatgat
     8641 gttaggtaca ttgtttgggt taaaaacagc caatgtcttt gctgaaaaag ttattgtcga
     8701 tccgtcaaat ccaatccaga acgtaaagaa taattttatt attccaaaag atgttcctaa
     8761 tgcaaaaaca aatattactg taaacggagc gtcaaaagtt tacaaatatc atgttgatgc
     8821 caacaaaggt ggttttacag acgactacgt aggattagtg gagggaaaca aaaatatacg
     8881 ctatccttct ttccaaaaag aatacggtga aacaaacctt gttttagaag gcgtaacaac
     8941 caacaccaaa gtcaatattg actatggaaa aatcggtacg tataacggga aaaaagtcaa
     9001 tatcaagcta gttctatcta atattcactt atactcggat acgttgccgt ggaatctact
     9061 agataacaac tatacaaaaa ctcattttcg agacgatggc tataaaaata cgaatggtgc
     9121 aatgagtaaa tctaaaaaaa gaacagtact ttggatctca gacaatcttt tctcaggaat
     9181 tgtttaccat tcaacacaaa tgaatgtgca gctagtagcc acatatgagg acggtagccc
     9241 cgttcaattt tcaggagata catttatcag ttttaactct ttgaaccctg caggaggaaa
     9301 aagcacggat cttaaaggag aatatgccca ctatgacaaa atgaatacga cagattggta
     9361 tgtcagaaaa gatacggttc tttcagaatt taaatctttc tacaacaatc tgaacgtggt
     9421 aggtggccac ccaggaggaa gctctaagct gacacaagcg gataatgatt tcaataattt
     9481 gcatgataaa ttaggagatc cgaagtttgg tcaaggtact gtgtccttta aaatatctga
     9541 agcaaatccg acgtttgtga ttggttcttc taatgttcaa acctggttta ctttatcttc
     9601 tgcgacaatc tttagtgttg ttcctgatca acctgaaaaa acaggggttg ataaaaatgg
     9661 aaataacgtg aacgataaaa tgttgcaagt aggagacacg attcaatatc gaatcaaaca
     9721 gaaggtgaat cgattaggag tggatttact agcggtttac gatcgatttg agttaatcga
     9781 taatttacca aaagaagtaa attacgtcga tgcacacgtt gaaagtggta caaataaaaa
     9841 attcgatgta tctggtgaag tgacctatga caaaacaaaa caccaggtaa aatatgcagc
     9901 gaaagctgat acattaaaaa atcgaatgaa gtataacggc gaaacttacg aattagtgat
     9961 caatgtaaaa gtcaatgaat tggccaatca aaatagtgta gccaaaaatc agggaacgtc
    10021 gatcattaat aaagtagaaa aggatacaaa tatcattacc gtttatttcc ctaaaattcc
    10081 agtgaaagaa gtacaacaaa atggaaaaga tgtaaacgga cgaaatgacg gtaagaaggg
    10141 tacgccgaca gctcctttaa acgcaggatc tgaagtacaa tatctagtca cacaaaaatg
    10201 gcacacaaaa ggcgtagacg ctgcgtcaga tcactacaaa caatttagta ttcaagatcc
    10261 aattgaagct cgtttgacat ataaagaagg ttctgcgcaa gtaatagata agagtaaagg
    10321 aaaagatatt acttctgaag gcacactaac ctatgatagc aattcaagaa cgctgaagtg
    10381 ggaagcttcc gctgacttct taagtaacaa tcttttagat ggacgagaaa ttcagctgat
    10441 atttacagct aaaactccat tacaatcaga aaaaaatatt gataaccaag ccgtagtagc
    10501 agtagataat gtttctaata aaacaaatgt tgtgacaatt ggggttgatc ctaacttgcc
    10561 acaggtcatt gttcctaaaa caggttctac acatttagta acgatttcag cggtcagctt
    10621 actattactt gtgttagcaa cttttagtta tgcggttctg agatacattt aaaataaaaa
    10681 aacgaaagaa tgaataaaat gaaaaagtta ataatagtag ttacttcctt gattgccatg
    10741 attgttattt tagtcggatg tagtaatgaa aaaaataaac aaactaatca agataatggc
    10801 gtattgaaat caggaactat gtggaaagaa gaagtaggtg gtcttgttta taatttgaaa
    10861 attatagacg agactacctg ggaatactct gagagtgtat ggcatccaga tcctgtacaa
    10921 ataacagtca agaggcaaaa agactataaa ggtttagaaa gatacaaaat agtagattca
    10981 gctggtgtta gggaatttat aaacaaatct gattctttat ttattgttgt tccctatgag
    11041 aagaatggcg taaaaaaaat aatttttctt ggatctagca aggatgaaaa gcgaacgaaa
    11101 gagaaattga ttcacgatgg atcacaatcc aataaatata agttacaaaa gactagcgag
    11161 tgattgctag tctttttatt tgtcctgaag gaggaatcac agtggcaaaa gctaaaacgc
    11221 catttgaaaa agccgcgtct aaaatcttag aacgccgcgg tgtatctgaa acacagtgga
    11281 aacaagaagt ccttgaaaaa gcacaatttg acctattacg gggaaaagac aaggacttag
    11341 aaggatatat ctatcaacgt gaacgtgaaa agcttgtttt cgatgaaatt attaaacact
    11401 aaaaggagcg aacaatttta tgtttgaatc aattacaatg aattttttaa cacaaccgaa
    11461 agtagtagct gcggttgata tttttagagc attacaaact gccgcaacta gtttaaaaaa
    11521 caatctgatg atttttgctg ctgctgcggc cgttgcttcc attgttattg ggggtctttt
    11581 cttcctattt ggacgaagag gagctgaaaa tgggaagatg cacgtaggct atgtattgat
    11641 gggggtagga gttattttag cagcagcttc tattgtggtt tcgttatttg gattgtttgg
    11701 acaaacacct caaggattat aagaaagtaa aaaagtagga gtaagaagta gtcgatactt
    11761 tttactcctt ttttatgaaa ggagaatact catgtacttt acgattgcag gcaataccaa
    11821 aacagataaa gagttaataa aaaaagcaac gaaggaagta ggaaagcgta cttctttttt
    11881 accgaaaaca attaaatatt ctgtcattga aacggaagaa cagctacatg tgttagggaa
    11941 agtactggaa cacgaaagtc gatcttctgt taagttgact ctcacgttac atgacacaga
    12001 aggaaaaata gagaaagctg gtacagaata cgtttttggc ccactggatt atcaaatttc
    12061 agaaggtttc tatcctacat tgatggattt aatccgcctt gatgtgttta aagaaacgga
    12121 tgaaactatg agtgtggaag agtcttatcg aaacgaaaaa cttttacaag ttttagaaga
    12181 agagttagag agcgaccaaa gaaaagtgaa tcaagggagt gaagtcgaag taaatgaaga
    12241 agtaccatgg gaacgaccaa tatttccaaa gaaggagtca aaagaaaaag agacagtcta
    12301 tgttgacgaa caagctgata ttccgactca gaaatcgata tttgaggaag agaacgatgt
    12361 gatgggtcaa ttggaggtag atccctttga agaaacaatg gaggatgaag agacggccga
    12421 agtagaagtt gatccagttg aagcgaatga agagtcaaca tggactgaag gggattctca
    12481 ggaatatatt gaaccactta tcagtgaaga agtagaaaaa aacgaaatag agatacaaaa
    12541 ggcaactgta tttgattata ttttggatca atatccgcca gagcatgaat ggatgaaaga
    12601 aaaaaacaaa ttatttttaa atgagcttta ttcgaaatat caattacccc aaacctatca
    12661 agcattttta gagagtaaag aagaattaat ctcacagggt aaaggcacac ttttagaaca
    12721 gttagagtct gtccaatcaa caaattggca tgagcttgca caagaagatt tattagccac
    12781 ctttgaagaa cgtcaacaag aaacagatca agaaattaat gagtatgcga cggaacagtc
    12841 gtctaattgg gagaaagcaa aagaggaact aaataaagaa gaacagcgag tgattgaaga
    12901 agaagtacaa aaaattaaag agcgatacga aaagaaacgc gacaatgcgt attccttgtg
    12961 tgtagcaaag atcaataatt ttactcagac gaatcaagaa gcgttatcga aagaaaaaga
    13021 aaacttgtta aaagaacgta ttaaagaacg aaaagaagaa ttttaccgag gtttgcgtac
    13081 agataagcta aagattagca aagaattaaa tgaacaactg aataagctat atcaaacaac
    13141 gactgaagtt cttatggaaa aatacgaaaa gatccagcaa gaattacaag tgcaaattcc
    13201 aaaatggaaa aaagagtatg aaattcaaca acaagaattg aaagaacaag aagaaaaaca
    13261 acggcaaaaa gaaaaagagc gcgaacaatt agaactaaaa aaacgtgaac aggatcttgc
    13321 ggaacaacaa atggcaatag aaaaacaacg gttaaaccaa gaaaaggaaa aagaagcagc
    13381 tgctcgtaag gaacgtcaag aacaaatgga tacattgcga caagctcagt taaattatct
    13441 agcacaacct caaccaacgc cttcagtagc tgctgttcaa accccaatga acaaccaaac
    13501 aaatctaact ccttcaccac agcgttcctt taacggatgg atggtgggat gtattgcaag
    13561 tttaagcttg cttctaggtg gaggaacagt atttgctttt aatcatatca atcaatcttc
    13621 acaggctgat tctgtggcca caacgacgtc aatcaaggaa gaagcccaag aacaagcaag
    13681 aaaagagtat gaacaacaat tagaagaatt attgaatcgt accaatcagt caacaacaga
    13741 gtcaagcatg gaaaatagca aagagagtga ttctagtaag gctaaagaag gatcaagcga
    13801 ttcaactgta caatcaaaca cttccgaaag ttcagaatca aatgaggtga aataatgcgt
    13861 gttagagaaa caacgaagcg aaaagacaaa cgattcaatt tagaaaagaa taggtatctt
    13921 tctcatttct atcgctatac tccctcagga gaagagctac cagaaaaaca tgacaaacgc
    13981 atttcgaaaa agatttttta tagtggactt gtatacctcc ctttagagta tttagtaaca
    14041 agagtaccag aagttttcaa ccgattggaa attgttaagg gaagcttaca aggaataaat
    14101 ctgtttcaat tacaggaaat gccacaggtc tttcattttg attcagctgg tttttggaat
    14161 ccatttactc ctacaactag tttgggtaca cgtttagcaa tttcgacagt ttgtgtggtt
    14221 ccagctgtac ttatgggatt gaaaatggac atgtggtttc gtcctctagc agatggacaa
    14281 aaaggggata atcgattaat gaccttaaaa gaaatccaac agatttatcc gcaaatacct
    14341 gaaacaaaaa ctacttttcc aggttatgga ggtattccaa tcacacatta caaaaaatat
    14401 tggtacattc aaacagatac tgttaatacg tgtattgttg gtacctctcg atcagggaaa
    14461 ggtcagattg aagtgttagc caccattgac aatttatctc gtgcagaaaa acaaagttca
    14521 atggtcgtta atgatccaaa aacagaatta tatgttggta gtaaagatga actagaagct
    14581 agagggtatg atgtatatgc ctttaatatc accgatccac tgcaatcaat gagtgataat
    14641 ccattggcac tcatcgtgaa atactggaaa cgaggagaca tagatactgc aacacagtta
    14701 accaatactt tcacaaatac gatttattat gatgccaacg cttcagataa caaatacttt
    14761 aacgaaaacg cgcagaaagc tgtcaatgcg cttatttttg cgttgttaga acaagctgat
    14821 caaacaggag attactccaa attgacaccg aataatctcg ttgagcttct ttctgagatt
    14881 ggcggtttta attattatcc agatccagac aatgaattca aacagttgaa tgccttagat
    14941 gaatttatga atcagttgcc acctggaaac attgcaaaaa aacaatatgg ggcaacgaaa
    15001 attggatctg ataaagcgaa gggaaatatt ttatcaacgg caatcacggg attgaatcca
    15061 tttactctaa cgaaaattgc aaagatgact tctcaatcaa cgattgatta taaatcggtt
    15121 gggtttccaa aatacttaga tttgaaatta catgaaagtc ttttaaatca acgagtcgta
    15181 gtagaatttt atcataaggg aaagaaattt catgaagaac gtgtcaaagt aggctataaa
    15241 ggattttgtg aaatcaattt tgattgtcat ttagttgcag gtgatcaagt ttgtttaaaa
    15301 tacgatcatc aaggaaaaga atatgtggct tggtatgaat tttctcaaag agtattgaaa
    15361 gacgaagagg gtaatatcgt ttatcggaaa aaacgaggag aaacccattt gccagaatta
    15421 gaaaaagaag ccgttctaac attagatgag gaaaaaagta acttattagt agagtctatt
    15481 cggatgcact ataccgataa accaatggct atttttatgc ttacacctga ttatgatcca
    15541 tctaaccata tcattgttag tatttttctt agtcagttat ataaagaatt atctacgcaa
    15601 tgtgttaaga ctaaaggaga taaatgtcac cgcaggattc attttatttt agatgaattt
    15661 gggaatatgc caccaatgga taatatggaa ggaatcatga cggtcacagc tggccgaaac
    15721 atgttgtggg atttgtttat ccaatcctat cagcaacttt atgcgaagta tggggaacaa
    15781 aacgcagcga ttatcaaaga aaattgtcag acacatattt atattatgtc gacagacgat
    15841 aataccatag aagaattttc caaaaaagtg gggaataaga cggttgaaca agagaacagt
    15901 accatcaatt cattaggtat gaatactcat atcaatcgca atgttgattc agatcgcatc
    15961 ttaactcctg aaagaatttc tactttttta gaaggtgaaa cgattgtact cgctccttta
    16021 aaacgacaag atttgaaagg tcataaaata cggccgtatc ctatttttaa tcatggggaa
    16081 acgaatcttc cttatgctta tcaatatatt gaagatttca atccatcgtg ggatatcaat
    16141 gatatagaca tacattgtac acatgcggac ttggatctta aggctttaca aattgattac
    16201 gattattttc tacctgatat ctatgcacgt cgactttatc acaatatgca cgatcaaata
    16261 gaagaggaag ctaaagaaaa catttttatt aaaatcgttc aatctttaga caactcaacg
    16321 gcacaaaagt tacttattca attttatgaa gagaagcaaa tagatcgttt gcaagaatac
    16381 cttgaaaaat tgcgtcaaaa tgaagaaatt acagaggtta taaggaaacg acttttgcta
    16441 gaagctgaaa aggcggtgaa agaatgatca ttggaggaat attttccggc attgccgact
    16501 ggtggtcagg cttatttggg gatggggatg caaaccccaa aaccgtaacg aaagtcttac
    16561 aagattatgg taattatctg cagtatcaag atgtatttag ttggatttgg aacacttttc
    16621 tgtggggatt gattaaagga ttatataatc tcaatacttt actagaaaaa accatttatc
    16681 aaagctttga tttaaaagac ttattgaacg ccgctggggt aaatgcacta tttcaaagtt
    16741 tgattagtaa ggtattggct cttttttgtg tcgtcacatt aatttattta ggcttgaaat
    16801 tttttatgag taaacaccca ccaaaagtca aaaatatctt ggttaattta tttatggcca
    16861 tgatcttgat ttttggtggt agttctttaa tcgatgaagg gttaaatatc agtaaaagct
    16921 tttacggaga cgtcactgca gcaaataaag cagataaaac gggatcacct gcttttcaaa
    16981 ttattcaaaa taatgtgatc gatgtcagta cgttactagc aactgacccg aataaagtag
    17041 aatccctacc aacagataaa agaaatgctt taacagcgaa aaattttaaa acagcgaata
    17101 tcaatgggat tattactcct gaacaagcta aaggtatggc aggtaatgat aaaagtgggt
    17161 tatcagatat acaaaaggat cggttaaagg cattacaata ccgattggaa ctagatgata
    17221 atgggaaaga aattcctgtt caaattagtg acgaaggctt agcaaaatat gtctatactt
    17281 cagggtatcg tcgatacagt agtaaaccag gtattatctt agctggtgaa tcttctttgg
    17341 cggtggccta tttatttatc ctatttacga tcgttacttg cattattgag ctggtattta
    17401 aaaaattcta tttagtgatt gccgcgtcaa cggactttga gacaggccaa cggatgaaaa
    17461 gtgcgataga agatatttct caatccttct tgttattggc gtttacgatt ttagaattac
    17521 gaatctatac attaatgctt tcaggtatcg gtgatttgca tgcggcagga aagatcaatg
    17581 gattcttgta tgttgttgct ttaattgtgc taactattgc gctattcaaa ggctctcaat
    17641 cggttacgaa gattttcggt gttgatacga gtctgaaaaa cggcagtaat tctcttctta
    17701 gcatgtttgc cttaggaaat attgcgaaaa atgtgggtag cggagctaaa aaccttgcaa
    17761 gtgctggtaa gagtggttta agccatttaa atgatattcg taaaaatgga tttggccatc
    17821 gaaaagatgt tacccctgat aacggggaag aacaatcaga cgataaagct acaactgtac
    17881 ctaatagtaa gaaaacagtt tccgaaatgt tcgggaaagc gaaaaatggt gtttctaaag
    17941 ccgcagaagg tcttggttac gtcaatgaac gtgggttaaa aggaacagct gaagatctta
    18001 cagaaaaagc caaagacacc ttagaagaga aattagacgg cacgagagct aaagaattgg
    18061 ctgaagctgt gaagaatcca tccgaagcac tagaaaaaca aaaagaaaaa gcttcagaag
    18121 tcaaagaagg actaaaagat gcgtatggtg aaggacaagt taatgcagca gtaaaagcta
    18181 atacaacaac cgaaaaagaa aatcaagaag gtatagtgat tccttcagtc aaagatcacc
    18241 aagaagcgtt gcactctaat gaaaattcga ttgaagagaa aaattccata gaagaaagaa
    18301 attcagaaga aggaaaaaat ggacagttac caaaaactga tccagaacaa tatcgctata
    18361 aacctaacag tgaccttgaa aatgagaagc gaatttcaga tttatcaaaa gtaaatcaag
    18421 aagacaaagc agaaaatgag ggacagttac caaaaactga tccagaacaa tatcggtata
    18481 gatctgttaa ctccgaaaat gaaaaacgca tttcagattt accaaaacga aatcaagaag
    18541 tacaaacgga tgaggattcc atcgttctgc caaatgataa tggaatcgaa gttggaactg
    18601 aaaaatcaac gaaaattggt ttacctaagg cacaaaattt accaatgaaa gatagtcgtt
    18661 tgaatcaatt caaggagaat gatcaaagct ttgttcacca atcaactgca ggtactgttc
    18721 aaatgaaacc aagtcgtttg cctgaaaatg gaaatctgac aactgtttct tacaatttat
    18781 ctgaaagtgg tgagacaggg aatgcgtccg ttcaaaatgt tgtgacaaga gaagctgcac
    18841 caaaacctat tcaaaacgtt catacaggtt acaagccagc aaatgtggca tttactgcac
    18901 caacaaaaat aaatgtgaca agagaaacta aaaacaggaa caatgcattg aaagaacaac
    18961 tattgaggga tatcaaacag gatatcaaac cataaaaggc ctacaagtta ggccttttct
    19021 ttatatgaaa aggagaaatc aattatggat aaatatataa acatgaaaaa ccctccaaga
    19081 tttagtgggg aatggaagtt tttcgccttt ttctttttgg atctattaac gcttggtggt
    19141 tgcttttttt gggcgaaaat agtcaataac cttgtccatt taccactctt ttttgcactc
    19201 ttgaattatg gcttatggat tgcgatagct ctagtgattg tttggcgacc ctataataac
    19261 ccaggtcaac gacaaatttt tgcgattatc gagtctattt tttttacgga caagaaccat
    19321 tatcatgcgt tagatcctaa ccgaaattat catggtacgt ataaggagga tgaataaatg
    19381 cgagtcaaag gacaaaattt agttgataag aaatccattt ttcagtttgg aaaaccagaa
    19441 gaacgatcta tcttggattt atttccttat aaatcctgta cagaagaggg agtcttagtt
    19501 actaaagaag atcattttca acgttattat cgtgtagttt ctacagacgt ggaaggatta
    19561 aatgaacaag agaaactaga acgaatgaat cagttgacca ccgtcatgcg tacgtatgtg
    19621 ccaacaatta agttagttag tttgaccaca gagacggatt taacggaaca aatcgtgcaa
    19681 aagcggcaat tattagataa aaatcgtatg gaacagtcct taggaagaaa tctacaacga
    19741 ttaaaaaaat atgaaaagaa attagtcgaa gaaatccagg aattgaaacg agcagaacaa
    19801 gaacgtcctg acttaagctt ctttttcgtc attgaaggaa agacaatcaa ggatttacaa
    19861 accagaaacc gtcagttaat gcgatctagt ggcattttag ggttaaaacc actctacaaa
    19921 aaagaattga tcaagattct gtatcgaatg aacaatatga atgatgagta ggaatggaga
    19981 agagagaatg aaatatccgt tgatatggtt agaaaaagat gttccgaagg aagagaccac
    20041 tagaaaattt cctcacactt taagcctggg taagttggga aaagggcaat cttttaacca
    20101 agtaaagaat caaacaagaa gaggtgactg tacatgttag aagcaattaa aacagctttt
    20161 tcaccacaaa atgatcaaaa agtacttgat ccattaaagc aactaggaaa tcgggaaata
    20221 gaaattttaa aatccaaagg gtatgattta gattttttaa aacaagtgat gccacaaggt
    20281 gggttaaatt ttgatgaaga atatgtgacg tatggtaatg gttattcacg atgtgtgaca
    20341 gtttatcact acacaaaaaa tcctacgctt ttttggttgg ccaatctcat gaacaatcct
    20401 catacagtgg ccacactcga tgttagcaca gatgaaaagc aaaaagtgat tgatcaaatc
    20461 aaccgcgcat tagatgaatt aaatgatcga tcagataatg aacgaaaagc gactgaccga
    20521 aataaaagtg cggaagaata cctggaatta gcggaatatg cccgaaaatt gacttctaat
    20581 ggggaaattt ctaaacaagt caaagtgaga gtacatgttt acggaaacac gattcaagaa
    20641 gtagatgaac gagcgcagga actgatcgaa aatctcaaag ggatggatta tcgtgcggtg
    20701 acttatctgc ataaaaccaa acgagattgg caatcgatgt ttaccatgtt cgatgaacaa
    20761 gctgaatggt tcggaaatat caaagggcaa tcactaccat cgttaaacat tggcggaggt
    20821 ttcccgttcc accaccaaac gctaaaagat ccaggaggga cacaatatgg ggaaaccatg
    20881 acaggcggcc catttgtctg gaatgcgacg tataaaaata gtgtacggtt gtctactaat
    20941 accttgcttc taggaatgat gggagctggt aaatcgaccg ttcttaaaat gatcgcggaa
    21001 gcccatttag ctgcaggaga ctttatttgg ggctttgaaa agggaaaaga ctttattcct
    21061 ttcttaaagg aatataacgg tattatggtg cgtttagacg gatctgacgg aatgatcaat
    21121 cctttagaga tatttgccac acggacgtat gatgaagcat ccagtttata tgacgatgga
    21181 tcagtcaaag atttgaagat caatgaagca gcgtcctatc aaacacactt agacaaagtg
    21241 gtctatcagg tacagttagt gagtcctcag ctaaaaggaa cgatgaaagc agaatttaag
    21301 acctacttaa atcgttttta tgaagagtat ggaacagtac cacgcggctt tacttcctca
    21361 aattcgcgtt caaatacgga gacgcaagtc acaggtaaag atccagaagc ttatccgacg
    21421 ttcaaagaat ttttagactt tttaggacaa ctggaattac caggtgcttc ccaagagaaa
    21481 aagaatcgaa aagaagaaat ggaatccatc gtagaatcct tatgtgagac gtatggcatg
    21541 atttttgatg gtcatagtac gattcgacac cttgaccaac aacagttggt cttttttgac
    21601 attgactcta ttacaggctt agatcgaggg gtacaacaat gtcagatgta catggccatg
    21661 acgttgattt ggaatcaggc attgattcaa ggacgaagac aacgacgctt aattaaagaa
    21721 aaacaaatgg aagaacaaga cttcaaacgc ttcttggcga tgattgatga gtgccataat
    21781 gcgattaatc cagatttcat tgaaacggta aattatgtca caaacttcca acgagaaatg
    21841 cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat ggtgccagaa
    21901 aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc ttctacgaag
    21961 atctttatgc gtatggatga atctatttta cgtcatatag aaggattagt tggtaaatca
    22021 atgacgaact cagaattaga atccattcct caacaaaatc aaggagacgc tgtgatcaat
    22081 tttggctcaa aagaaaccat tcgtgttcat tttagtccga acaaacgtca attaaaattg
    22141 tttgatggag gaaaataatg gaaaaccaaa atgaaagttt aatcaaacag tatgttaagc
    22201 gtcgtgcaaa gcggcgctta tttttgtggg tgtttggtac ttctgcaggt ttgattacta
    22261 tattgatcac tgtgtttgtg accctttttc taatacttgc ggcaggttct attgataatt
    22321 ctgattcaag tagtggtggc gaagctttta caggagaata ttcggaaggc ttacccattt
    22381 ataaagaaat caaaggaaga ggcccttttt ctgatgagat tgcgcaatat gctgtaggtg
    22441 cagcagtgaa gtataaatta ttaccaagtg tgatcctttc gcaatacggt tatgaatcag
    22501 cgtttggtac gtcggcgtcc gcaagaaatg atctcaatta ttttgggatt acgtggtttg
    22561 atgggtgtct gtttcctaaa ggaactgcgc gtggaattgg tggcattgaa ggtggctggt
    22621 acatgaagtt tcccaactca aaagctgcct tctcctatta cggctttatg gtagccacac
    22681 aatcaaattt taatgcttgt gtcggaaata aaagccctgg cgcaagctta ttgatcttag
    22741 gacgaggagg gtatgccgcc gcaggaatta ctgaagacag tgcctattat aaaaattgta
    22801 tgtctattat taatacaaat aaattgatgg agtacgatga gtttgcgatt aaacactgga
    22861 gagaaggcgg cggaactggt ggtacgatta caggaagctg gggcaatcca ttcccaggaa
    22921 gtagcttaga taaaaattcg ttcagtggag gacaactttt tgggaaaaat ccaggaggag
    22981 aattccgacc taacgggttc catgatggac tagactttgg ttcagtcgat catccaggaa
    23041 gtgagattca tgcggttcat ggcggaaaag tcgtgtacgt tggcaatcct ggtatttcag
    23101 gtttgggtgc gtgtgtgatc gtgattaatt acgatggctt gaatatggtg tatcaagaat
    23161 ttgcaaatag tacaggaaat tctcgagtga aagtaggcga tcaagtgaaa gttggtcaag
    23221 taattgggat acgagataca gcacacttgc atttaggatt tactcgaatg gattggcgtc
    23281 aagcacaagg acatgcattc attgatgatg gtacatggat cgatccgtta ccatttttga
    23341 atagcagcaa aaaatagatc aggagaaaaa atatggaaaa taaaacctta aaaatcgtct
    23401 taacagctgc aattagcgtt agtttaatcg gcaatattgc gttgttttgg cagcttaaag
    23461 aagaacaaga gacaaatacc tataaaattg aagaagtggc taaaaacgcg tctgataagc
    23521 tcaaaaaaaa ttcttctgag gcacaggcga agatcgacaa gttaaatcaa accatcaatg
    23581 agaaaaacca agaaatcgat cagctgaagc aacaagatgg cacaaaagca aaagaggaag
    23641 taactgaagc acaaagaaag acggcagaag agttcggtca attggccatt gataaatcat
    23701 taagcagaaa tgaattaacg gaaaaactaa aagatgtcgc aacccaagaa gtgatcgaca
    23761 aattaagtcc tgcagacgat gatcaccaac atgacgacta cggaagttac tcttttacat
    23821 taggtgacgt gcaaacttac gctcaaacaa gcagtgtaaa agaggaacaa aattttgtcg
    23881 tatttgttga ttatacaatc ggcaatcctc aatttaaaga tgtcaaacca caaaaaataa
    23941 aaggtggatt aactgtcact gaaaaacaag tagatggtca atggaaagtc acagacttta
    24001 gttatttcac tcgttaggag gaagaaaatg agtaagaaaa aaggagcaag acaacgtttt
    24061 aaaaaacgaa aaagttatct tagatggctg gggatcttta tgattctcgg ctttttgatt
    24121 cttgctagtc cgatttacac acataaaaag gtagacatac cagatgaagt aagcacgaac
    24181 gcatttttaa acacgaagga actgacgatg gtttcaaaag aaaaaggagc gaaccagcaa
    24241 ttagtttttg aatttgcgat cgacgatgaa gatcagagct tattaaaaga actagctaat
    24301 cttaattatc gtgtagaagt aaagacagct aaaggggatt atcaagcaat aaaagccaaa
    24361 gtgatcaagg tgtctgatga ttattttgta gtgaagttag cacatgtacc agaagaatat
    24421 atcgccatgc gtttaaccat tattcctgaa aaaattgatc caaaagtgga tatgcaagaa
    24481 ccacaagatc tgatttatta cgttcacgaa gataaggtta aagatcaagt gaaagatgaa
    24541 gattatgaac aacatgcgat caattacaaa gtgaaaggat acaaaaaaga acaaaaagca
    24601 gcacaaaaac aaatggaatc cttccaagca accattgatt tgaatgaaga attagtgaag
    24661 aagctaaaag atcaattgcc ttatcaagtc gcagatgatc aggaaaatac tgaaaacaag
    24721 attaatagct accagcaaga aattgaaaca tcgaaaacgc aaatgaaaga tcaagaagag
    24781 atcattcaaa aacttcaaga aaaaattgat cgtatgacaa aagaaaagat ttagaaggac
    24841 aggtggagtg aaaaaatgaa gcgaacaaac ttggctgaca aagatacttt cgctgagcag
    24901 aaagtattga ttaaagccta tctcaaagtt gtaaaagcta aagaaatatg tcgagaagtg
    24961 aatttatcta atacaacaat atctgagttg aagaatggtc gaaagaattt agatacttta
    25021 aaattcagat catttgaagc tctatatgta gctgctaaaa aatattttac agctgataac
    25081 aaataaaaaa caggagtatt ttatgtgaaa aaagtatata aaaaatgctt atgaatcagc
    25141 tatatcacct taaccatttg ttaatgagat gggagaaaac attaaccacg attctaacgc
    25201 aaacatcaag cacataaaac atttaacact cctcctttct ggctgaagat ttcaaccaaa
    25261 caggaagaca gcgtatcaat tatagcatac actttttctt aaattcattt ttcatatgac
    25321 aaaatatttc cttctaatcg acaaagttag aaggattttt tattgtctaa atacacaaat
    25381 aaccttaatt tataaagagc ataaggaaac gtgggaacac tttttaaaaa aagtgttcca
    25441 ataggctgtg cctattacgt ttctcaaaaa taattgtggg aacaaaatat ttaaaaatag
    25501 gatagtgaaa ggatagcaaa ggatagtaaa aggatagaag caggatagcg aaaaggatag
    25561 gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag aataagaaat
    25621 gtagatgaga aaatcgtaag agaaattgat cgaagatgtg acgaactaag taaccgaacg
    25681 ggtaataaat ggagtcgtaa cgattattta aagctactcg ttgaaaatga ttttgatcgt
    25741 cctttgatgg aatataaaca agataaattt gatcaattat taaatcagtt aatagataaa
    25801 ttttcttttg ttcaaagtca taatacaaaa gtattagaag aatatatttg tcagaataat
    25861 caaattatcg aacttttaat tgaacaaagt agaggaggag aagtttaaca tggccaaagt
    25921 tatagacaag catatttatt tttatgaaac acatatagat gttctagatg aaattattgc
    25981 aactcatgca gaggttaaaa actatagtga agccgttcgg tttctatgta tgaattatga
    26041 ttcagaagtg gagaaaaaag taaattccaa tcaagcaaag ttgaatgcaa tgggaaaaga
    26101 aatttctatt ttaaccgaaa tggtttcaga gtttgcggat ctccatttga aagatacagg
    26161 gattttaatt ggtacaaatt caactgttta ccaagaagca aaagagcgtg tggaaggcaa
    26221 gataaaagca aatcaaacga agaaatattc tcctaagata aagaaaacaa taagcgaatc
    26281 agtgactaca aaaagtgaag tatttgatcc aacaaggttc ttaaaacgat aaaaattaga
    26341 aggagaatgt gatgagtaaa tcacctgcag tcattctcac ttgtcaattt accttgccca
    26401 ataaaaaatc tttttcaaca tacattgatt atatgacaag agaaaaagcg ctggaagaaa
    26461 aggaacgacg tacgcccgag gaagaacagg aactgcgtct aatcaagaat gctttagagg
    26521 atttttatat tcctgaagga gaaacttttt cggagagtaa gacgggtaaa gaattcagcg
    26581 aaacgtcgaa tgaagcgcaa tcgttgatga aacatggaat caattttgac aagttagaag
    26641 aacaagattt taccaaatat ctttcttata tgacacgtca ctatgcgtta gaacaaaaga
    26701 aagtactgac gcatagtgaa caaaaagaat accaacgctt gaaccaagca ataaaaaaat
    26761 atcaaacaga gccacacaaa aaagcttcag gaaatcttcc tggagttttt tctatggctt
    26821 cagacgaagt gaaaggaagt gatctgaagg agatcaagca aaccttccaa agaggacaac
    26881 aaaaaggctc aatcatttat caagatgttg tctctcatga tcattcgtat cttgaaaaaa
    26941 taggattgta cgatcccaaa acagatactt tagatgaaga aggtttaaaa gcagctggaa
    27001 gaaaaatgat ggagacattg ttcgagaaag agcaactgaa tgaaacaggc tactggatgg
    27061 caacgattca ccgaaatacc aaacatatcc atattcattt tgcagttgtt gaaaaaaaaa
    27121 atacgcgtaa accatacact gagattgaaa atggtgtgag ttatatcgta ccgaaaggga
    27181 agagaaggca agcaacatta gacgaaatga agactaatta tgtacatgag ttagaacgtt
    27241 tttcttatga aaaaaatcga atgggtatgg agaaacgaaa tttattgaca cggaaaagtg
    27301 atttgcgtaa caccttaacc aaagtagtga aagagccagt acgttatgat cgacacgcaa
    27361 tgagcttatt aactgaagta tataaaaact tacctaaaaa gcgttcggaa tggcattacg
    27421 gggatgaaaa tcgaaccaaa ctttcaccat acacaagaga gaaactcgat gagttaaccc
    27481 aatatgtgtt aacaaaagaa cctggatatc aagaatatat acagatttca aaagcattga
    27541 aagaagaagc aaaaagtctt tatggggaaa gcaagagaga atcaaaggat gcagaaaaaa
    27601 atgctctctt tgatttaaaa aagcgcacag gaaatgccat tctaacagaa ctgaagaaac
    27661 aggatagtca aataaaacct ttaatagaaa ggatggatca gatgcaatct atttacaatg
    27721 aacgatcctt tcgaacactt aaacagttgc caacgaatga atacaaatat agttacgaag
    27781 aattcatgaa gcgcaggaaa caattccaac aaagagttgt cacgcaacgg agtttgcgtc
    27841 aattaaatcg aacgattaat gcccatgaag aaaaatacca cgcaagtaaa gcatacgaag
    27901 agcaacaacg aagaattcaa atggaacaag aaagacagta ggaggaatag caatgaaaca
    27961 atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa tcgaacaact
    28021 tcccgattgt ttagaaaaag agcatttgtt tcagataaga gaaatgttga gaaacgaaca
    28081 gtttgatcca aatcaatttt tagtcgttga gtactcagct actggtgtgt actgttgtaa
    28141 tcatgtgaag ggtgaaaaat attttatcat tcaagaatat gagggcaagt tagcgcctta
    28201 ttatactact tgggaaatga atgaagaggg gatcaataac ttcccgtgta aaagcattga
    28261 agagtctatt tcactcacag aatgttagtt gttaagtgaa taaaagaagt aaaagagtcc
    28321 tgaacgtaat tgtccaggac tctttttttc aatgaattgt tttccgccaa ttcaatgagt
    28381 ggtgcgattt gcgactacat tatatcaaaa gaaagagaag ggaggaagaa gaaatggctt
    28441 attcaacgat tggagttgtt gttgaaaaaa gcagagacaa tctcgttttt gtgacagaaa
    28501 ttcaaacggg cagagctttt gtcgtcacag acaaagcggc aaaagcgtat caaagtggcg
    28561 atattttaac gttaaatctg actacgaaga cgttcgtcga tgcggcagaa gattatccat
    28621 t
//
LOCUS       DAZKPE010000034        28526 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000034 DAZKPE010000000
VERSION     DAZKPE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.034"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            174..638
                     /gene="lspA"
                     /locus_tag="ACG930_001620"
     CDS             174..638
                     /gene="lspA"
                     /locus_tag="ACG930_001620"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFQ0518782.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            635..1546
                     /locus_tag="ACG930_001621"
     CDS             635..1546
                     /locus_tag="ACG930_001621"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFQ0518783.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            1781..2320
                     /gene="pyrR"
                     /locus_tag="ACG930_001622"
     CDS             1781..2320
                     /gene="pyrR"
                     /locus_tag="ACG930_001622"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFQ0518784.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            2334..3617
                     /locus_tag="ACG930_001623"
     CDS             2334..3617
                     /locus_tag="ACG930_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFQ0518785.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            3630..4556
                     /locus_tag="ACG930_001624"
     CDS             3630..4556
                     /locus_tag="ACG930_001624"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFQ0518786.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            4575..5855
                     /locus_tag="ACG930_001625"
     CDS             4575..5855
                     /locus_tag="ACG930_001625"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFQ0518787.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            5860..6936
                     /locus_tag="ACG930_001626"
     CDS             5860..6936
                     /locus_tag="ACG930_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFQ0518788.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            6941..10126
                     /gene="carB"
                     /locus_tag="ACG930_001627"
     CDS             6941..10126
                     /gene="carB"
                     /locus_tag="ACG930_001627"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFQ0518789.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            10180..10956
                     /locus_tag="ACG930_001628"
     CDS             10180..10956
                     /locus_tag="ACG930_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFQ0518790.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            10953..11885
                     /locus_tag="ACG930_001629"
     CDS             10953..11885
                     /locus_tag="ACG930_001629"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFQ0518791.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            11882..12598
                     /gene="pyrF"
                     /locus_tag="ACG930_001630"
     CDS             11882..12598
                     /gene="pyrF"
                     /locus_tag="ACG930_001630"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFQ0518792.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            12605..13234
                     /gene="pyrE"
                     /locus_tag="ACG930_001631"
     CDS             12605..13234
                     /gene="pyrE"
                     /locus_tag="ACG930_001631"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFQ0518793.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            13222..13536
                     /locus_tag="ACG930_001632"
     CDS             13222..13536
                     /locus_tag="ACG930_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518794.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            13574..14215
                     /locus_tag="ACG930_001633"
     CDS             13574..14215
                     /locus_tag="ACG930_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFQ0518795.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            14258..14950
                     /locus_tag="ACG930_001634"
     CDS             14258..14950
                     /locus_tag="ACG930_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFQ0518796.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            14947..15849
                     /locus_tag="ACG930_001635"
     CDS             14947..15849
                     /locus_tag="ACG930_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0518797.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(16007..17713)
                     /gene="efbA"
                     /locus_tag="ACG930_001636"
     CDS             complement(16007..17713)
                     /gene="efbA"
                     /locus_tag="ACG930_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFQ0518798.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            17903..18526
                     /locus_tag="ACG930_001637"
     CDS             17903..18526
                     /locus_tag="ACG930_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518799.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            18976..20025
                     /gene="trpX"
                     /locus_tag="ACG930_001638"
     CDS             18976..20025
                     /gene="trpX"
                     /locus_tag="ACG930_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0518800.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            20022..20903
                     /locus_tag="ACG930_001639"
     CDS             20022..20903
                     /locus_tag="ACG930_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518801.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            20906..21676
                     /locus_tag="ACG930_001640"
     CDS             20906..21676
                     /locus_tag="ACG930_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518802.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            21955..22809
                     /gene="aroE"
                     /locus_tag="ACG930_001641"
     CDS             21955..22809
                     /gene="aroE"
                     /locus_tag="ACG930_001641"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFQ0518803.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            22987..24150
                     /locus_tag="ACG930_001642"
     CDS             22987..24150
                     /locus_tag="ACG930_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0518804.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            24267..24677
                     /locus_tag="ACG930_001643"
     CDS             24267..24677
                     /locus_tag="ACG930_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0518805.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            24851..27079
                     /gene="topB"
                     /locus_tag="ACG930_001644"
     CDS             24851..27079
                     /gene="topB"
                     /locus_tag="ACG930_001644"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFQ0518806.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            27250..27534
                     /locus_tag="ACG930_001645"
     CDS             27250..27534
                     /locus_tag="ACG930_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518807.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            27694..27930
                     /locus_tag="ACG930_001646"
     CDS             27694..27930
                     /locus_tag="ACG930_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0518808.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            27927..28326
                     /locus_tag="ACG930_001647"
                     /pseudo
     CDS             27927..28326
                     /locus_tag="ACG930_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
BASE COUNT         9392 a         4957 c         6304 g         7873 t
ORIGIN      
        1 aaattatcat tttgttccag ctaaaacaca tatttacgag gttgaagcga tgtttcgtga
       61 gcaagggact ttggaagccg tacttatcac taaagatggg aatcccgatg gtaatctgct
      121 cgggatcgta cgacctcgtg atatttataa acaaatagaa aaggattgat tttttgttaa
      181 ttatttattg gatattcagc gctttgctag taggagtgga tcagttggtc aaatggtgga
      241 tcactgataa tctagcgctt ggagagacga aaaatcttat accaggtatt ttgtcactga
      301 atcatattcg aaacactgga gccgcatgga gtatgctaga agggaagatg tggttcttta
      361 ctatagtgac actcattgca gtcgttgtga ttctcacatt gatgattaaa aatcgtgaaa
      421 aaggtaatcg ctggttcatg attggattga gtttgattct agctggtgcg attggcaatt
      481 ttatcgaccg tattcgtctt ggctatgtag tagatatgtt ccagacagat tttatgagct
      541 ttccgatttt taacgtagca gatgtgacac ttgtatgtgg agtgatttgt atgttaattt
      601 atattatttt agatgaaaag gatcaaagaa aaaaatgaca gaacttaaaa cgacgattca
      661 ccatgaatct ggtaggatcg ataaagtatt gactaattta ttcaccgatt acagtcgttc
      721 gcaaattcag ctgtggctga aaaatggagc ggtttctgtc aatggacagc cagtcaaagc
      781 aaattacaaa gtaaaacaag gagacgagat tactgtcttg atccccgaac cagaaacatt
      841 agatgtggtc ccagaaaata tcccgttgac gatcgtttac gaagatgaag atgtagcggt
      901 gataaacaaa cctcaaggaa tggtcgttca tccttcagca ggtcatacgc atggcacaat
      961 ggtcaatgcg ctgatgtacc atatcaagga tctttctacg atcaacggcg ttattcgtcc
     1021 aggtattgtt caccgaatcg acaaagatac ttccggactg ctaatggttg ccaaaaatga
     1081 ccaggcacac gaatcattag ctcagcaatt aaaagataag acctctttgc gcaaatatgt
     1141 tgctttagtc catggagaga ttcctcacga aaaaggaacc atcaatgcgc caatcggccg
     1201 ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat gggaagtcgg ctgtcacaca
     1261 ttttactgta ttggaacgtt tcgaaggatt tactctggtt gaattaaaac tagaaaccgg
     1321 aagaacacac cagatccgtg tgcatatgaa gtatatcggt tatccgttag ctggagatcc
     1381 agtatacgga ccgaagaaaa ctttgaaagg caatggtcag tttctccatg cgcaaatgtt
     1441 aggttttacg cacccgacta caaacgaaaa gatgatcttt gaagcacctc ttccagaagt
     1501 ttttgaaaaa actttagaaa aattaagaaa aaacattgca ttttaattta gataacggta
     1561 ttgtaattaa caacgaaagc ataaaactta atagaattcc tttaagttta gtcccgtgag
     1621 gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat aagtagattg ctcattgaca
     1681 tagtatagct atcagtgtat cagtatacgc tcagtctaaa cattcctcct gtcctcttag
     1741 ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa atgcaagcaa aagaagtagt
     1801 agatcaggta accatgaagc gagcattgac tcgaattact tatgagatta tcgagagaaa
     1861 ccatagtatc caagatatcg tattggtagg tatcaaaaca cgaggaatct acattgcatc
     1921 aagaattgcc gaacgcctga agcagctaga agatatcgat attcctgtag gagaactgga
     1981 tatcacttta taccgagatg acaaaaaaga aaatccagaa gaaccggaac ttcattcttc
     2041 tgacatccca gtttccttag aaggaaaaga agttattttg attgatgatg ttttgtatac
     2101 aggacgaacg attcgagcag caatggacgc agtaatggat tttggcagac caagaaaaat
     2161 ttcattagca gtcctggtcg atcgtgggca tcgagaattg ccaatccgtg cagattatgt
     2221 tgggaagaac attccaacat ctcgggcgga agagatttta gtagagatgc aagagcttga
     2281 tggacaagat cgcatcatga ttttgaaaga ggaagattag aggagagaga aacatgtcgg
     2341 agaaaaaagg atttcataat gatgacgtgg tgttagatat ccacgatcgc ccaaccccag
     2401 gacattgggt aggattaagt ttacaacact tgttcacgat gttcggagca accgtgttag
     2461 tccccatctt agtaggtatc gatccaggta ttgcgctagt cagttcagga ctaggtacat
     2521 tggtgtactt atttactact aaaggaaaga tacctgcgta cttaggaagc agcttcgctt
     2581 tcattgcagc gatgcagctt ttgatgaaaa cagatggtta tccagcgatt gcacaaggag
     2641 cagtcacaac tggattagtc tatttgattg ttgcgctgat catcaaaaag atcggttcag
     2701 catggctgga taaaatcttg cctccaatcg tcgtcggtcc agtcatcatg gttatcgggt
     2761 tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa tcagggcacg tatgatttca
     2821 agtatattgc tgtagcgctg atcacattag gattaacaat tttcttcaac atgtggctaa
     2881 gaggttttct cggattgatt ccgattttac taggtattat tagcggatac atcgtagcct
     2941 tgctgtttgg aatcgtggat actaagccaa tcgtagacgc tgcctggttt gctgttccta
     3001 actttgagat tccctttgta caatatgaac caaagctata tcttggagca atcacaacaa
     3061 tggcacccat cgcttttgtg acgatgacag agcatatcgg ccatcttatg gtattgaata
     3121 aactaactaa acgtaatttc tttgaagaac cgggtcttca taagacgttg acaggtgatg
     3181 gattagcaca aatcgtggca gcctttgtcg gaggtcctcc tgtaacaagt tacggtgaaa
     3241 acattggtgt tctggctatc acacgtgtcc atagcgtgtt tgtgatcggt ggagctgcag
     3301 tatttgcagt cattttagga ttcgtaggaa aattaagcgc tttgatttta agtatccctg
     3361 gaccagtcat ctcaggaatc agttttatct tatttggagt aattgccgca agtggaatga
     3421 agattttaat cgagaacaaa atcgattttg ataaaaagaa aaatctgttg attgcttcag
     3481 ttatcttagt agtaggaatt ggcggactcg tctttgaagt aggcacattt acattgtcgg
     3541 caatggcatt agcaactgta cttggcatca ttttaaatct tatcttacca gaaacttcac
     3601 gaagcgaaga aaactaagga ggaaacatta tgatcatcaa atcagaacgt atcagcttaa
     3661 agcatttatt gaccgttgag gcacttactg atcaagaagt tatgggcttg atccgcagag
     3721 ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa gcgccagtac tttgctacaa
     3781 acctcttttt cgaaaatagt actcgcacac ataaaagctt cgatgtagcg gagaaaaaac
     3841 tagggctaga agtgattgaa tttgaagcaa gcacaagctc tgtccaaaaa ggggaaacac
     3901 tatacgatac agtactgacg atgtcagcat taggcgtaga cgtagcggtt atccgtcatg
     3961 gtgatgagaa ctattatgac gaactgatac aaagtaaaac aatccagtgt tcgattatca
     4021 atggaggaga cggaagcgga cagcatccaa cccaatgctt gcttgatttg atgaccattt
     4081 atgaagaatt tggtcatttt gaaggtctga aagttgccat cgtaggtgat atcactcact
     4141 ctcgcgtagc taaatccaat atgcagatgt taaaacgtct aggcgcacaa gtattcttct
     4201 caggtcctag agaatggtac gacgatgaat tcgaagtgta cggacattat atgccattgg
     4261 atgaactact agatcaagtt gatgtcatga tgatgcttcg ggtgcaacac gaacgccatg
     4321 atggaaaaga aagtttctca aaagaaggct accatcagga acatgggtta acagttgagc
     4381 gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc agcaccagtt aaccgtgatg
     4441 tagaattagc tgattcatta gtggaaggat tacagtcgcg gatcgttcag caaatgagca
     4501 atggagtatt cgtcagaatg gcaatcttag aagcagtgct aaatggaaaa gcgtaattat
     4561 aggaggatga aaaaatgaaa acactcatta aaaacggtca gatcaataca cgaaaaaata
     4621 tgacgacacc agcagaaatt tggatagaag atgggcgaat caaagcaatc ggtacaggat
     4681 tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg acaattgatc acacctggtt
     4741 tagtggacgt ccatgttcat ttgagagagc caggatttac atacaaggag acgatcgaag
     4801 ctgggactcg ctcagctgct cgtggcggtt tcactactgt atgcgcgatg ccgaatttaa
     4861 atcctgtacc tgatacggca gaaaagctga gacaagtata tgacatcatt agaaaagatg
     4921 cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa tctgcgaagt gagaaattag
     4981 ttgatcaaga agcactgatt gaagaaggtg cttttgcttt cacaaatgac ggtgtaggtg
     5041 tccaaacagc tgggacgatg tatctggcta tgaaagaagc tgcaaaaaac aataaagccc
     5101 tagtagccca tacagaagat gaatctttat tatttggcgg cgttatgcac gctggcaaga
     5161 aggcagaaga acttggtctt cccgggatct taagcgtaac cgagtcttct caaattgcta
     5221 gagatctgtt gctagctgaa gcaactggtg ttcattacca tgtttgccat gtttctacta
     5281 aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg aatccacgta acagcagaag
     5341 tttcacccca tcatcttatt ttgatcgacg aagatattcc cgaagatttc ggcttttgga
     5401 aaatgaaccc gccgctaaga ggacgggagg acagagaagc tttgatcgaa ggcttgcttg
     5461 acggtacgat cgattgcatc gctacagacc atgcccccca tggattagaa gaaaaaagcc
     5521 aaagtttcat gaaatcacca tttggtatcg taggaagcga aacagcgttt caactgatct
     5581 atactcattt tgtagaaact ggtcgattca cgttggaaca agtgatcaat tggttggcag
     5641 ttaaaccggc tgagattttt ggtttgaatg caggaacgct aacggttggt gcccccgctg
     5701 atgtagcagt ttttgatatt acacaaactt gcacgatcga taaagaagac tttttatcaa
     5761 aaggggagaa tacacctttt atcggctgga aagtaaaagg cgaaacacaa atgacttttg
     5821 tcaacggaaa acttgtgtgg cagaagggag aataaaagta tggaacgttt gcttatatta
     5881 gaagatggaa cagttttcga aggaaaggct tttggtgcag atgctagtgt cttcggagaa
     5941 atcgttttta caacaagtat gactggttat caagaaacta tcactgatca aagttttaac
     6001 ggtcaaatca ttacatttac ctatcctatg gtgggtaatt atggggtaaa tagagatgat
     6061 tatgaatcga tttctccaac atgcaaagga gtagtagtaa aagaacatgc acgtgtagct
     6121 tcaaactggc gaaaccaaat gacgctagat tcatttttga aacaaaaagg aattcctgga
     6181 atatcaggta tcgatacgcg cgcccttact cgcaaaatcc gtgaagtcgg aacgatgaaa
     6241 gctagtatcg ttgatgctgg agattccttc gaacatgcat ttgatcagct gaaagcaacc
     6301 gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca aaccttatcc aagtccagga
     6361 acaggtcgga aagtcattgt cattgacttc ggcttgaaac atagtatttt acgagaattg
     6421 agtaaaagaa actgtaacct cacagtactt ccctataaca cagatgccga gacgatttta
     6481 gcgctatcac cagacggagt catgctgacg aatggacctg gtgatccaaa agatgtgcca
     6541 gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac cgatttttgg tatttgtctc
     6601 ggtcaccagt tatttgcttt agccaacggt gcagatacct ataaaatgaa attcggacat
     6661 cgaggattaa atcacccggt acgagaagta gcgaccggaa gaattgattt tacttctcaa
     6721 aatcatggct atgcagtcga tgaagccacg attgatccag aaaaactcat cgtaactcat
     6781 gtagaagtaa atgacggaac agtagaagga gtcaaacaca gagattatcc cgctttcagt
     6841 gtgcagtttc atccagatgc tgcccctggt ccgcatgatg cactacattt atttgatgaa
     6901 tttatggaaa tgatggacgc aggaaaggag cagtaaacag atgccgaaac gtacagatat
     6961 caagaaaatt atggtgattg gatctggtcc gatcatcatt ggtcaagccg cagaatttga
     7021 ctacgcagga acacaagcct gccttgcctt aaaagaagaa ggatatgaag tggttttagt
     7081 aaattctaat cctgcgacga tcatgacgga taaagaagtg gcagatcaag tatatatcga
     7141 accgatcaca cttgaatttg tatcaaggat tcttcgaaaa gagcgtccag atgctctcct
     7201 tccaacttta ggcggacaga caggcctcaa tatggcaatg gagctggcag catcaggtat
     7261 tttagaagaa ttgaacatag aacttctagg aacaaagctt tctgcgatcg atcaagcaga
     7321 agatcgtgat ctattcaaac agttgatgaa agaattgaat cagccaatcc ccgagtctga
     7381 aatcgtcaat acagtagaag aagctgtaga ttttgcaaat aaaatcggct atcctgtcat
     7441 cgttcgtcca gcctttactt taggcggaac tggtggaggt atgtgtgaaa atgaagaaga
     7501 attacgtatc gtatcagaaa atggattaag tctttccccc gctacccaat gtttgattga
     7561 acgaagtatt gcaggtttta aagaaattga atatgaagtg atgagagatt cggctgataa
     7621 tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg ggtatccata caggtgattc
     7681 tatcgtattt gcccctagtc aaacattgtc tgaccatgaa tatcaaatgc ttcgtgatgc
     7741 ttctctttcg attattcgag cacttaagat cgagggaggc tgtaatgtcc aactcgctct
     7801 tgatccacat agttttaatt attatgtgat tgaagtcaat ccgcgtgttt ctcgttcatc
     7861 tgcgttagca agtaaggcga ctggctatcc gatcgctaag ctagctgcta aaatagcgct
     7921 tggattaaca ttagacgaaa tgaaaaatcc tgttacagga acgacttttg cagaatttga
     7981 acctgcatta gattatgttg tagctaaaat tcctcgctgg ccgtttgata agtttgaaaa
     8041 cggagaacgg cttttaggca cgcagatgaa agcaactggt gaagtgatgg ctatcggtcg
     8101 gaatatcgaa gagtctttat tgaaagctgt gcgttcttta gaaatcggta cacaccatat
     8161 cgaacttcct gagttggcag acatcacgga cgatgaccta atccaaaaag tggttcgagc
     8221 acaagatgat cgcctgtttt atgtagctga agctattaga agagggtaca ccatagaaga
     8281 attagcggat ttgacaaaaa tcgatttatt ctttttagat aaactgttgc atatcgtaga
     8341 aatcgaacag cagttgaaac agcagccgtt ggatgacaag atattgaaaa cagcgaaaca
     8401 aaacggtttt acagacaaaa aagtggcgga gctgtgggaa ataaacgaag aagccgttcg
     8461 ccagatgaga aaagaaaatg atttgattcc tgtatataag atggttgaca cttgtgcagc
     8521 ggaattcgaa tcaaaaacac cttattttta tagttcctat gaatatgaaa atgaaagttc
     8581 acgatcagaa aagccctcaa ttctagtact gggatctggt cctatccgta tcggacaagg
     8641 ggttgaattt gactatgcga ctgtgcattc tgtcaaagca atccagcagg caggatacga
     8701 agcaatcatc atgaacagca atcctgaaac agtttcgact gacttttcta tttcggataa
     8761 attatatttt gagccattga ccttcgaaga tgtgatgaat gtgatcgagc tagaacagcc
     8821 gataggagta atcgttcaat ttggtggtca gacagcaatc aacttagccg aacctttgac
     8881 tgctgctggt gtaaaaatct tagggacaac gatcgaagac ttggatcgtg cggaaaatcg
     8941 tgatttattc gagcaagcgc tgaaagagtt ggatattcct caacctttag gggatactgc
     9001 tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt ggttatccag ttcttgttcg
     9061 tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt gaaaaccagc gagatttaga
     9121 agattacatg gaacatgctg tgaaagcatc tccagaacat ccagtactag tggaccgtta
     9181 cttgcttggc ggtgaatgcg aagtggatgc gatttgtgac ggtgaaacag tactcatccc
     9241 agggatcatg gagcatattg agcgtgctgg tgtccattca ggggattcaa tggctgtgta
     9301 tccacctcaa acattatctg aatcgatcaa gaaaacgatc gaagattaca cgatccgctt
     9361 agcattaggt ttgaattgtg tcgggatgat gaatatccag tttgtcatcc atgaaaatga
     9421 ggtttatgtg atcgaagtca atcctcgagc aagtcggact gttccattct taagtaaggt
     9481 gacaggaatt ccaatggcac aaattgcgac gaaagctatt ttgggagaga aactaaagac
     9541 acttggttat gaaaacggac tttatccaga aacaaaagaa gttcatgtta aagcacctgt
     9601 cttttctttt acgaaattgc agaaagttga tacttactta gggcctgaaa tgaaatcgac
     9661 tggagaagta atgggatctg acagacaatt agacaaagct ttgtacaagg cattcgaagc
     9721 ttctggatta cacttgcctg aatatggagc cgtattattt acgattgcgg acgaaacaaa
     9781 agaagaagca ctagaattag ctaaacgttt tacagaaatt ggctatagtc tgataggaac
     9841 gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc gttgaaacag tagcgaaaat
     9901 ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata agagatggta aaacacaagt
     9961 ggttgtcaat acgattgata aagatcgggg aaatgcttct aaagacggtt tcatcatccg
    10021 aagagaagca gttgaacatg gtattccatt gtttacttct ttagacacag cagatgcgat
    10081 cgttcgagtg atggaatccc gtgctttttc aactaaccct atttaacggc gagcacatgt
    10141 taagacaaaa agacgaaaaa ccgttgcagg aggggacaga tgaaacaaga aatgatggaa
    10201 atcgttcagc aaaaacagct ggcaccaaag atttttgaaa tgacattgaa aggtgatcta
    10261 gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc tcgtgccgcg tgcagacttg
    10321 ctattacgcc gaccgattag cttgaatcat atcgaccacg aaacaaatac ttgccgtatc
    10381 atttatcggg tggaaggtga ggggactaga gtcttctcta ctctttctgc cggagaccat
    10441 ttagatgtca tgggtccttt aggcaatggt tttgatttgt ccaatcttca tacaggagac
    10501 gaagtattta taatcggtgg aggaatcggt gtccctcctc tatatgagtt atcaaaacag
    10561 ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt ttgccacaca tgaagtcgtt
    10621 tattatgaaa aagaatttaa tcgtctagga gaaacaagaa tcgctactga cgatggaaca
    10681 tacggtatgc acggaaatgt cggtaattta ttgttaggaa cgaagacgga acctacagct
    10741 gtttttgcat gtggttcaaa cgggttattg aagacagtgg aacagctgtt ttcttcgcat
    10801 caaaatgtcc agttatcatt agaatcccgc atggcatgtg ggataggggc ttgctatgct
    10861 tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa gtgtgaaagt ttgtgacgaa
    10921 ggaccgattt ttaaaatagg agaggtaatt atatgaatga gaatccttta gcggtcaaac
    10981 ttcctggcct agaattaaaa aatcctatca tgccggcaag cggctgtttc ggttttggca
    11041 aagaatacgg aaaatactat gatttgaatc agcttggatc gatcatggtc aaggcaacga
    11101 ctccaaatgc ccgctttggc aatcccacgc caagagtggc ggaaacacca tctggcatgt
    11161 tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt tatgcataaa cttcttccag
    11221 aattagagga gtacaatgag ttacccatca tcgcaaatgt tgctggtgct tgtgaagaag
    11281 actatgtaga agtttgtagc aaaattggcg aagcaccaaa tgtgaaagca atcgagctga
    11341 acatttcttg cccaaatgtc aaacatggcg gaattgcttt tggaacagat tctgatgttg
    11401 cttttcaatt aacacaagca gtaaagaaag tttcttctgt tcctgtctat gtcaaattgt
    11461 ccccaaatgt aacagacatc gttccaatcg ctcaggcaat cgaagctgga ggggcagatg
    11521 ggtttacgat gatcaatact cttcttggta tgcggattga ccttaagaca agaaaaccga
    11581 ttttagccaa tcaaacaggt ggactctccg gaccagcaat caagcctgtc gctattcgtt
    11641 tgattcacca agtagcaagt atatccagcc ttccaatcat tgggatgggc ggcgtgcaga
    11701 cagtggatga tgttcttgag atgtttatgg ctggagcaag tgctgtagct atagggaccg
    11761 cgaatttcac cgatccgtat atctgtccta aactaattaa agagctccct gtgcgaatga
    11821 gcgaactagg catcgaatcg ctggaaagat taatcaaaga agtgagagag gaacgtgaac
    11881 gatgaatcaa ctagaccaac gaccaattat tgcattagat ttttcaacta ggcaagaggt
    11941 agaagacttt cttcgatttt tcccgaaaga agaaaaattg tttgtgaaaa tcggaatgga
    12001 attgttctac caagaaggac ctgaaatcgt acgttatcta aaagaggctg gtcataatgt
    12061 atttttagat ctgaaacttc acgatattcc gaatacggtc gaaaaagcaa tgcggggatt
    12121 ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct ggcggtattc gtatgatgga
    12181 ggcggcaatg cgaggattag aagaggggac tccagaaggt ggaaaacgtc cgctacttct
    12241 agctatcact cagcttactt ctacaagtga agaagaaatg catgccgatc aactaatcga
    12301 agtttcttta gaaaaaagtg tgatccatta tgctagctgt gccaaaaaag caggattaga
    12361 tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa gaaatggcag gagacgaatt
    12421 tgtttgctta actccgggta taagaccaga aggaacagtc gcaggagatc agacaagagt
    12481 agtcacacct tctcaggcaa aaaagatcgg ctcaactttt atcgttatag gtcgaccaat
    12541 cactcagtca actaatcctt ataaagcata tcaaacgatt caaacagaat ggagctaacc
    12601 taaaatgaat gttgaacaaa gtatcgcaaa agacttatta gaaattgaag cagtattttt
    12661 aaatccaagt aatcctttta catgggcaag tggaatcaaa agcccaattt actgtgataa
    12721 ccgaatcacg atgagctatc caaaagtccg aaaagagatc gcaaaaggat tagcaagcaa
    12781 aatcaaagaa gcttaccctg aagtacaagt gattgctgga actgcaacag caggaatccc
    12841 tcatgccgca tgggtagcgg aaatactgga tttgccaatg gtctatattc gaagtaaggc
    12901 gaaagatcat gggaaaggta accaaatcga aggacgtata tttgaaggtc agaagatggt
    12961 tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg gaagcagctg aagcagcaaa
    13021 aagagaaggt gcggatatcc ttggtgttgc ggctatcttt acgtatgagt tgccaaaagg
    13081 aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg ttgaccaatt attctgtatt
    13141 gattgaagca gctttagaag atcgttatat cgatgagcaa gaattaactc tgctaaaaga
    13201 atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc ttgatgaaga tagagaaatc
    13261 cgatttgtgt ctccagaatc atcaattgga atagcaaaaa tccaaaaact gattgcgaga
    13321 agcatctttt catcaggtat gaaaagaaac ttctatcgtg atcagttttt gattttttta
    13381 aaattcattt ttctaagact ggttagcaga aagaagagaa taatctcttc tcttttttct
    13441 attatatata gattttctct attttttggt aagggagctg tttcaaaaat ggtaaagagc
    13501 ggaaatgttg cgaatatcag ttatttaatg atatgatatt cggaaaaaga aatctcaaag
    13561 ggaggtaact tttatggggt tgaatgaatt tattttagga ttgaacaatt tagagacgat
    13621 cacaagggca cctggatttt ttaaatatac agagcataca gttgcagcac attcgtatcg
    13681 tgtagcatct attgcgcaag ttctaggaga cattgaagaa gcgaatggac aaccgatcga
    13741 ttggaaactg ctctatgaaa aatcattgaa tcatgactac acagagcgtt ttattggtga
    13801 tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga gggatgctgc aaacagttga
    13861 agaaaagatg acggacgaat tcatcaacca agagattcca gctgagttcc aagaagttta
    13921 tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa ggagaactat tagccatttc
    13981 agataaggtt gaccttcttt atgaatcttt tgatgaaatc atcaaaaata acccggaaaa
    14041 agtttataag gagatgttca ttgaggcagt gactacgatt aaaagctttg aacatcggcc
    14101 ttctgttcag tatttcttta aagagatatt tccggaacta ttgaaccagg aattttatgg
    14161 aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag aaagaagaaa aataaaaatg
    14221 atatgagatg cagggggaag tatagttgaa aaagaatatg gatgtcgaat ggggctattc
    14281 tggagacaaa ggtccggaaa attgggcgag tttatgtgat tggtttgcga gaggtgcgga
    14341 atttccattg cagtcgccta ttcatttgac caagggggaa gaaaccaaaa tagaaggaga
    14401 cacgctttcc tttcattatc aaaagcaacg gtttactgac aaggaattca aaaacacgat
    14461 tcatttagta ccttttgacc aactcagtta tgtagagttc aagaaagaac gctattattt
    14521 gacagatatt catttccact tgccttctga acatatcatc aacggaaaac aggaagatat
    14581 tgaatttcat tttgttcata tgaacagcaa aaaagagaat ctagttgtgg gtgtcatgta
    14641 ccagctaatg gtacaggaag gttggctgta taatcaagaa aatggggaaa gttggaactt
    14701 agaaaaacat gagcattggg taaatccgga tgtgttcttt ccggagcaaa aaagccattt
    14761 ccattatatt ggctcattga caactccgcc taccagcggg ccaatccaat ggtttgtaat
    14821 ggatcatgta ggaaaactga accaagagtt tcttctcccc ttcgatggtc agtatgctcg
    14881 accgaacaac cgaccaatcc agcccttgaa tggaagagaa atttattatt tcgaggagtt
    14941 tgagcaatga atattcagca gatgaaatac gtggtcgctg tagcaaacaa tggtagtttc
    15001 agagaagcgg caaagaaaat gtttgtctcc cagccaagtc tttcagctgg tatcaaagaa
    15061 ttagaaaccg agttagggat cacgctgttt actcgaacga atcgaggggc atatttaaca
    15121 gaagaagggc aagacttctt aaatcgtgcc gagaaaatat tggtccagct tgatacatta
    15181 gaaactcact atctaacgag tgaaaagaga gacaattttt cgatcgctgc ccagcattat
    15241 gatttcttag gtcctttgac cgcacagcta ctcgaggaat tcaaagacga gatcaaacaa
    15301 tttcggatca tggagacgac aacagcgaga gtgatcgaag aagtcaaaga gcagcacagt
    15361 gagatcggca ttatttatat gaatgagcat aatcaagctg gtatcagaag atatttacaa
    15421 caaggagagc taagtggccg cagcattgga aaattcaaaa cgcatatttt tttaaggcaa
    15481 ggacatccat tagctgaaca cgcagagatc accaaagaag aattgttatc ttatcctcaa
    15541 gttcgtttta cacaggatgg aaataatttc ccgtattttt atgaagacct tatcgagatc
    15601 cctgatcaag aaacagtgat ttatacgagt gatcgaggta ctttgatgaa tatcgttctt
    15661 gaaactgatg cttacgcttc aggatctggt attgtgattg gagggattcg cgagcacttg
    15721 cggttaatcc ctttggcaga aggcgaacta aatgaatttt atatcattta ttcggcgaaa
    15781 cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc ttactcggtt actggaccag
    15841 cagagctaag aaaagcagat gagaacgctg tttattgaac accgttgatc aaaaaagagg
    15901 ggttgtgaca gaattttgtc acaactcctc tttttgtagc aaacaattta taactaattg
    15961 ctgttgtggg aaagtacgca aatatgattc tagaaacact cattgattac ctgttttgtt
    16021 tcatagctgt aattttttct tcttctggtg tcacgataat cgtcttttgg ttttcataaa
    16081 taacataacc aggcttggcg ccatttggtt ttcggatatg ctttacctgt acaagatcaa
    16141 ccggcacttg ggcagagtat cggtattttg aaaaataggc agctaactcg gcagcttctg
    16201 taattgtttc atctgagggc ttgtcacttt taatgatgac gtgcgaaccg ggtatatttt
    16261 ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat tgtcagctgg tcattttgaa
    16321 gattgttttt accaacaaga atgagcgttc cgtcagaaga aaagtattga tcaggctgag
    16381 atggtttctt acgtttttgt ttttttaagt tcttcttttt caggtatcct tctgaagtca
    16441 attcttcttt aattgcttcg atatccattg ggccggcaat ttccagttga gataagacag
    16501 attcaagata ttggatttca tctttggctt cttggatttg ttcgccaatc agcttaacag
    16561 cgttcttcag cttttggtat cgatggaaat atttctgtgc attttgattt ggtgtcaatg
    16621 ccggatctag tgctattttg attggccgat cttcttcata ataattaggt aaaacaactt
    16681 cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag tagttcgcca tttctacggt
    16741 aattctcagc gttttcggat tctttgagtg tttgttcacg ttttttcaat ttatttttat
    16801 ttcgttttag ttcattttcg atttttcgaa tcagttctcc gccttgttgt tttgcccgat
    16861 ctttctctgc tttttcgtga taatagctat ctaataattg actgagtgtt ggataagctg
    16921 ttacagcaga tgcctgttcg gacaatacct gataagcaat cggtgtgaaa aaatctttat
    16981 tttccgtttc gtaaaaagta ggaataggct gatggctgat ggctgagaaa aattcgtccc
    17041 atacaaccat cttttcatta ggacgttcca gtaatctttt ggtcagctct tgagcgatat
    17101 cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg atctagttca gtttgggaaa
    17161 gccgctgaaa gattttttct ttctcggagc taaatgggtt caagacctct tgttttggcg
    17221 gagcaacata ttctacacca ggaagcaaag aacgataagt gttttgagag cttccaatgt
    17281 gtttgatcgc atccagtatt tttccagttt ctcgattaac taagacgatc gtactatgac
    17341 gtcccattaa ttcaacgatc aatatgatat tttgtagatc acccaactcg tttcgtttag
    17401 caaagtggaa atggatcact cgatcatttt cgatttgttc gatgtcttct aaaatagcgc
    17461 catccaaata ttttcgaagc atcatcacga agttaggcgg attatcagga ttctgataat
    17521 cgatttgggt aatctgtaca cgagcataac ttgggtgcgc agataataat aatcgatggt
    17581 ttttgccgcg tgaacgaatc accagcacga tttcattttc ataaggctga tggattttcg
    17641 agatccggcc agatagtaac gtttcacgca attcgttgac catcgcgtgg gtaaatacac
    17701 catcaaagga catggttcat tcctcatttc ttttcataag tatattcatt ataacgaaaa
    17761 aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag tctagaaaaa tcttggacta
    17821 attacataaa aaacagtgtt tctatcgttg aaatccaaat ttttaggtat aataaaaaat
    17881 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
    17941 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
    18001 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
    18061 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
    18121 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
    18181 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
    18241 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
    18301 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
    18361 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
    18421 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
    18481 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
    18541 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
    18601 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
    18661 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
    18721 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
    18781 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
    18841 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
    18901 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
    18961 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
    19021 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
    19081 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
    19141 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
    19201 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
    19261 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
    19321 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
    19381 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
    19441 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
    19501 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
    19561 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
    19621 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
    19681 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
    19741 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
    19801 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
    19861 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
    19921 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
    19981 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
    20041 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
    20101 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
    20161 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
    20221 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
    20281 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
    20341 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
    20401 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
    20461 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
    20521 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
    20581 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
    20641 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
    20701 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
    20761 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
    20821 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
    20881 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
    20941 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
    21001 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
    21061 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
    21121 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
    21181 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
    21241 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
    21301 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
    21361 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
    21421 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
    21481 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
    21541 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
    21601 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
    21661 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
    21721 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
    21781 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
    21841 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
    21901 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
    21961 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
    22021 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
    22081 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
    22141 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
    22201 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
    22261 tataatactg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
    22321 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagca
    22381 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
    22441 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
    22501 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
    22561 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
    22621 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
    22681 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
    22741 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
    22801 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
    22861 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
    22921 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
    22981 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
    23041 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
    23101 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
    23161 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
    23221 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
    23281 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
    23341 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
    23401 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
    23461 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
    23521 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
    23581 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
    23641 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
    23701 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
    23761 gtagatatta aaaaaggggg ccagaagatg gatggacatg ttcttttgca gtacgcacgt
    23821 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
    23881 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
    23941 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
    24001 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
    24061 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
    24121 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
    24181 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
    24241 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
    24301 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
    24361 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
    24421 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
    24481 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
    24541 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
    24601 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
    24661 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
    24721 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
    24781 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
    24841 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
    24901 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
    24961 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
    25021 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
    25081 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
    25141 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
    25201 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
    25261 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
    25321 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
    25381 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
    25441 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
    25501 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
    25561 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
    25621 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
    25681 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
    25741 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
    25801 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
    25861 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
    25921 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
    25981 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
    26041 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
    26101 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
    26161 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
    26221 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
    26281 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
    26341 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
    26401 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
    26461 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
    26521 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
    26581 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
    26641 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
    26701 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
    26761 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
    26821 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
    26881 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
    26941 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
    27001 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
    27061 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
    27121 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
    27181 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
    27241 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
    27301 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
    27361 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
    27421 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
    27481 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
    27541 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
    27601 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
    27661 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
    27721 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
    27781 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
    27841 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    27901 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    27961 tcaacgcgaa agttatttta ccgtcactcg ccaggcgaaa tgatcggtgt aaaagatgca
    28021 aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca agaactctat
    28081 cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa acatcctttt
    28141 cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca attgaataat
    28201 tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat taccactagt
    28261 tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca aaccgcaata
    28321 aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta aggaatatgc
    28381 tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg aaaatatgga
    28441 ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag gaaatagtgg
    28501 tttagaacta gtgggctgat ttttta
//
LOCUS       DAZKPE010000035        27231 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000035 DAZKPE010000000
VERSION     DAZKPE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.035"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(159..443)
                     /locus_tag="ACG930_001648"
     CDS             complement(159..443)
                     /locus_tag="ACG930_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518809.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(461..1351)
                     /locus_tag="ACG930_001649"
     CDS             complement(461..1351)
                     /locus_tag="ACG930_001649"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFQ0518810.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1371..1589)
                     /locus_tag="ACG930_001650"
     CDS             complement(1371..1589)
                     /locus_tag="ACG930_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFQ0518811.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1559..3259)
                     /locus_tag="ACG930_001651"
     CDS             complement(1559..3259)
                     /locus_tag="ACG930_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFQ0518812.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3526..4299
                     /locus_tag="ACG930_001652"
     CDS             3526..4299
                     /locus_tag="ACG930_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518813.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="ACG930_001653"
     CDS             complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="ACG930_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFQ0518814.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5015..5117)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5123..6094)
                     /locus_tag="ACG930_001654"
     CDS             complement(5123..6094)
                     /locus_tag="ACG930_001654"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFQ0518815.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="ACG930_001655"
     CDS             complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="ACG930_001655"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFQ0518816.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8064..8882)
                     /gene="purR"
                     /locus_tag="ACG930_001656"
     CDS             complement(8064..8882)
                     /gene="purR"
                     /locus_tag="ACG930_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFQ0518817.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9049..9873)
                     /locus_tag="ACG930_001657"
     CDS             complement(9049..9873)
                     /locus_tag="ACG930_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFQ0518818.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9846..10526)
                     /locus_tag="ACG930_001658"
     CDS             complement(9846..10526)
                     /locus_tag="ACG930_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518819.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10549..11487)
                     /locus_tag="ACG930_001659"
     CDS             complement(10549..11487)
                     /locus_tag="ACG930_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFQ0518820.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11732..12583)
                     /gene="ispE"
                     /locus_tag="ACG930_001660"
     CDS             complement(11732..12583)
                     /gene="ispE"
                     /locus_tag="ACG930_001660"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFQ0518821.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="ACG930_001661"
     CDS             complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="ACG930_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFQ0518822.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15451..16257
                     /gene="proC"
                     /locus_tag="ACG930_001662"
     CDS             15451..16257
                     /gene="proC"
                     /locus_tag="ACG930_001662"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFQ0518823.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16336..17892)
                     /gene="rny"
                     /locus_tag="ACG930_001663"
     CDS             complement(16336..17892)
                     /gene="rny"
                     /locus_tag="ACG930_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFQ0518824.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18303..19352)
                     /gene="recA"
                     /locus_tag="ACG930_001664"
     CDS             complement(18303..19352)
                     /gene="recA"
                     /locus_tag="ACG930_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFQ0518825.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19461..20702)
                     /locus_tag="ACG930_001665"
     CDS             complement(19461..20702)
                     /locus_tag="ACG930_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFQ0518826.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="ACG930_001666"
     CDS             complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="ACG930_001666"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFQ0518827.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21729..22652)
                     /locus_tag="ACG930_001667"
     CDS             complement(21729..22652)
                     /locus_tag="ACG930_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFQ0518828.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23390..24676)
                     /locus_tag="ACG930_001668"
     CDS             complement(23390..24676)
                     /locus_tag="ACG930_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFQ0518829.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24669..25937)
                     /locus_tag="ACG930_001669"
     CDS             complement(24669..25937)
                     /locus_tag="ACG930_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFQ0518830.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26189..26650
                     /gene="mscL"
                     /locus_tag="ACG930_001670"
     CDS             26189..26650
                     /gene="mscL"
                     /locus_tag="ACG930_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFQ0518831.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26709..27155)
                     /locus_tag="ACG930_001671"
     CDS             complement(26709..27155)
                     /locus_tag="ACG930_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518832.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7740 a         5873 c         4723 g         8895 t
ORIGIN      
        1 ataccgagaa aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga
       61 attttgtcac aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat
      121 tctgattatt tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa
      181 gtattcacta cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct
      241 acctcttctg tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg
      301 ttgatcaaaa taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca
      361 aagccgtttt tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg
      421 aacgttacgt cataatattt cattatctct acctctttcg tcattcaata ttttgtactt
      481 gttctctgat tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg
      541 catttgattt ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta
      601 attcccgacc tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg
      661 ccagacgatc cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca
      721 acaaccgttg ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta
      781 tttgaaattc cttttcatag atttctacaa aactatcgag tttttttagt acttctttga
      841 attcttcagt attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg
      901 cctcaataga atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca
      961 tgctctcttc cggtttttct tctaccgtta cgaagttttc gtccagcgcg aagcgttccg
     1021 ccatccgact aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca
     1081 attgagtgat aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc
     1141 caatataagc tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa
     1201 gctgacgaaa atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta
     1261 gaaaacgctg gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga
     1321 tggctttgcc aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt
     1381 tctattgctt tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt
     1441 ttttcatggt ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg
     1501 actaggttca gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct
     1561 acgatttcat atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata
     1621 ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt
     1681 ttccttgtag cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct
     1741 ggtattttcg ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat
     1801 catccggcat actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat
     1861 agatttcatt gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc
     1921 atgtctctgg tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc
     1981 ttttgaaaaa agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc
     2041 agtatgttct tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta
     2101 atcgtttttt catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa
     2161 aaagcagaaa gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg
     2221 gcatacgaat ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg
     2281 ctcctttgtt aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt
     2341 tattttttcc gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc
     2401 aatctggtat ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg
     2461 gcagtttagt agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat
     2521 ccaaattgtc tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg
     2581 ctgttttcgt catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag
     2641 ccatttctgg taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt
     2701 ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga
     2761 taatctcaaa gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac
     2821 cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt
     2881 gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag
     2941 attgaaataa aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc
     3001 gaaaaaattt tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat
     3061 ctcctctact tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag
     3121 cacattgctt ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa
     3181 atggaagggg ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt
     3241 aaactttttt tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa
     3301 aaggtcatga gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct
     3361 cctttaaata aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat
     3421 gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat
     3481 gttgtaaaat aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt
     3541 tatgtacata ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac
     3601 tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct
     3661 gctggagaat atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag
     3721 cgtttctttt cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt
     3781 actgatttaa cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt
     3841 ggtcatatga aaacacatct tcattcgccg tttttttata aactacagaa taattttgta
     3901 tacttcgatc ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat
     3961 aggatttttg ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct
     4021 tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt
     4081 aatttgatgc aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa
     4141 tatcgtatcc caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat
     4201 cgagaagagg aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg
     4261 gtagaagatg ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat
     4321 aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt
     4381 tacagctcct gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat
     4441 aaaacgatga tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa
     4501 aagagccaag gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata
     4561 aaatgccaaa aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta
     4621 atttgtttcg tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct
     4681 gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa
     4741 taaacttgtc ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc
     4801 tttgtccctc ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa
     4861 ctgctgccga tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt
     4921 ccttctaccc aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc
     4981 acaaaggagg aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc
     5041 tcgcataacc gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga
     5101 ctcccctttg tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt
     5161 tgttttcatg gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga
     5221 ttttgtcgat tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga
     5281 tagctgaatc ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag
     5341 catacacact agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg
     5401 ctgtatcgat catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat
     5461 tcattacttc tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt
     5521 tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga
     5581 caacatcatc gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca
     5641 tcaaatgatc gactggaata tcaaagaaac cttggatttg aactgcatga aggtccaaag
     5701 tcagcattct tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg
     5761 gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt
     5821 tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt
     5881 tatcattgac tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt
     5941 cttcaatgtt tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact
     6001 cgacgccgac tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa
     6061 tttttaatct tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa
     6121 ctctagaatt ctacctaata aatagtagtc atatttttta aataaatcaa gtgattttgc
     6181 aaaagtctta gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg
     6241 ctctcgcaat tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa
     6301 tcgaactgtt tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc
     6361 tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac
     6421 cacatccgac attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga
     6481 ctttagttcc tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt
     6541 tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct
     6601 tgacatggct gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt
     6661 ctacgatttt tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga
     6721 tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg
     6781 tcgttgctga atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc
     6841 tcatgatctc atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa
     6901 aatcatccgt ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat
     6961 ctgttagata gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca
     7021 aagcttcgtt gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg
     7081 gtgttgcatc tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc
     7141 gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc
     7201 cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac
     7261 tgataactaa cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat
     7321 gtcctgttcc caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt
     7381 taacttgttc tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga
     7441 cccgattaat gatatgttct accataggtt taccagaaac gggatgtaaa actttatata
     7501 attttgactt catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca
     7561 actgcgtcac tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt
     7621 caacaaaaca agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc
     7681 ataacgggcc tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca
     7741 cactactcat aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa
     7801 acggtaggct tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc
     7861 tcaataaacg gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca
     7921 ggacgctgat ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa
     7981 gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa
     8041 ctaagcagct ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata
     8101 tttttcgttt gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg
     8161 cgatgaccgt tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat
     8221 tcttcaatca agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact
     8281 acaaggacac gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt
     8341 tcagaagatc cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc
     8401 cggcgtacaa taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg
     8461 ccttttgtgg ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg
     8521 attcttccaa cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat
     8581 cctcctggaa gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt
     8641 ttcgcctctt catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt
     8701 gtttccaagg ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca
     8761 ctgatagaag atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca
     8821 tgcgggtgat tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc
     8881 acctattcca actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa
     8941 aaattcgagc attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga
     9001 agcctataaa aaatttttcg tttttataag gcttcttttc tttataattt agttattttt
     9061 tcttctgaag gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa
     9121 gactaatgtg attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga
     9181 cagcatccct agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc
     9241 taatcgcata ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc
     9301 aatcgggatc atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa
     9361 atgaacgggt agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg
     9421 ccgtttgaat aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac
     9481 ttgctcccat gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga
     9541 attccctccg ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat
     9601 ggcaatggag atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc
     9661 tgctaataca acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa
     9721 cgctacccct gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat
     9781 cactaaaaac acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc
     9841 tcttctcatg aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg
     9901 atctgtctgt ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat
     9961 ttcccatgga catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca
    10021 tccatacctg ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc
    10081 gctaaactga ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata
    10141 tcccacatcc ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga
    10201 cgcttgaacc agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta
    10261 ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt
    10321 ccttcttgat ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac
    10381 gatgctttca ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca
    10441 cccgcatcta catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc
    10501 aaatcagata tttcgatata acgcacctta caacctccat tctaaaactt aattgatact
    10561 ttcttttaaa gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat
    10621 ttgttcatta gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt
    10681 cgacaatgtc tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt
    10741 gtttttcttc acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg
    10801 tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc
    10861 agcatgctga gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg
    10921 atccagtgct tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt
    10981 atctggatat ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac
    11041 cggatcgagc caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc
    11101 ttcatgttcg tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat
    11161 caaggtctgt ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga
    11221 actattatac acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc
    11281 gaaatcatgc ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac
    11341 gatctctttt gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt
    11401 tttgtctgct tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac
    11461 cgtagctgtc aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt
    11521 ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc
    11581 atcaatttct gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg
    11641 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
    11701 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
    11761 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
    11821 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
    11881 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
    11941 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
    12001 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
    12061 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
    12121 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
    12181 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
    12241 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
    12301 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
    12361 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
    12421 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
    12481 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
    12541 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
    12601 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
    12661 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
    12721 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
    12781 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
    12841 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
    12901 cagactggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
    12961 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
    13021 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
    13081 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
    13141 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
    13201 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
    13261 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
    13321 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
    13381 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
    13441 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
    13501 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
    13561 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
    13621 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
    13681 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
    13741 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
    13801 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
    13861 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
    13921 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
    13981 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
    14041 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
    14101 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
    14161 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
    14221 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
    14281 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
    14341 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
    14401 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
    14461 ctactgctac atcttgccga acaggcaatt gactcattcc taagatcatc aaaacgtcaa
    14521 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
    14581 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
    14641 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
    14701 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
    14761 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
    14821 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
    14881 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
    14941 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
    15001 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
    15061 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
    15121 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
    15181 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
    15241 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
    15301 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
    15361 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
    15421 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
    15481 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
    15541 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
    15601 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
    15661 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
    15721 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
    15781 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
    15841 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
    15901 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
    15961 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
    16021 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
    16081 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
    16141 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
    16201 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
    16261 tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
    16321 cttttgtatt ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac
    16381 tttgatgtgt ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa
    16441 acgaacagcg tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc
    16501 agcttgaact gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact
    16561 tcttaaacga cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga
    16621 gagcgcatct gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg
    16681 atgagaagcg atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc
    16741 accgatctca acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag
    16801 caacccggca cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc
    16861 taattttgca acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg
    16921 cagacgtccg atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc
    16981 tgcctcttcc ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat
    17041 ttcttcgata cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg
    17101 tgcgatttct cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc
    17161 gatgattaaa tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc
    17221 aatgatacga cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga
    17281 aacttgatct gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc
    17341 tgcttcttct ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag
    17401 ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat
    17461 tttttctagt tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc
    17521 aattaattgc tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt
    17581 ttctaacgag tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg
    17641 agattttaat tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg
    17701 attttcttcc ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc
    17761 actatcgatg attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga
    17821 ctttgcgacc ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat
    17881 gttgaatacc ataaaatcca cctccatact atctttttca tttttatcat ctatacagct
    17941 tctatgataa attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa
    18001 catgcacaac tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa
    18061 acggctttct acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat
    18121 aggtaaacct ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata
    18181 tttttatttt atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa
    18241 aaaacggcag gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat
    18301 ttttattctt ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact
    18361 tcttcaccaa taccataagc tgctctaact agagcagaaa cttctgccat catttcagga
    18421 tgattagcca tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa
    18481 gaataccaag caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct
    18541 ccttcttgtg agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt
    18601 gctactttgt tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt
    18661 ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt
    18721 cctccaggag tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg
    18781 atgaaaatag cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga
    18841 gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct
    18901 cgtggaacta aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact
    18961 aaagcatcag cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca
    19021 tcgatattca cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg
    19081 aaagcggccg ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt
    19141 ttacctgaac tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca
    19201 cctaaagcga catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt
    19261 ttttcgccca atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca
    19321 gcatctaagg ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat
    19381 cagagcaaca tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac
    19441 cgaacaaata ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct
    19501 tgcataaccg cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa
    19561 accacgccgt ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac
    19621 gtgtccggtc cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt
    19681 gcttgaatgg ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc
    19741 tccggatcaa tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct
    19801 ggaaatactt cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc
    19861 aaactttccg ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt
    19921 gctagcgaat tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt
    19981 tcttctaatg ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt
    20041 cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca
    20101 atcagatctt ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact
    20161 ttagaaatta gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc
    20221 acaaacattg gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct
    20281 gtttgataaa aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg
    20341 ataatctggg actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat
    20401 gccaataatt ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca
    20461 gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt
    20521 tcacttcttg tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca
    20581 actgtttgat aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca
    20641 ttcgtattca cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc
    20701 attacttccc gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag
    20761 agggcaagga gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc
    20821 tcctgccaaa acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg
    20881 aaattatccc ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata
    20941 cttacattga tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga
    21001 tagtaaagat cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga
    21061 atgggatatt attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt
    21121 ttcccggcca agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg
    21181 tgacggctaa ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt
    21241 caaccaacat gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact
    21301 tgccaaaatt agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga
    21361 tactagctaa agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc
    21421 ctacgttaaa ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca
    21481 tacaaattct aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc
    21541 ctattctacg tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt
    21601 tattcaaagg agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga
    21661 cacagatttg tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat
    21721 ttatacgatc attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt
    21781 tcccctggat taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca
    21841 ccaatcgtga tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt
    21901 gctgccagtg tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga
    21961 ttgacagcag taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg
    22021 gcactgccag aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt
    22081 gttgattcta ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc
    22141 tcgactgatc cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga
    22201 cgatcttgcc aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat
    22261 aaaatgacag gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct
    22321 tttctagaag tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg
    22381 cttttcccat caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat
    22441 tgccgaataa atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg
    22501 attgcttcca aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt
    22561 tttttattca ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca
    22621 tcttctccag tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt
    22681 tgggtgctgt gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct
    22741 gccaactcct cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact
    22801 tgttccttgt gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca
    22861 atcagctgtt cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt
    22921 atgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt
    22981 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
    23041 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
    23101 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
    23161 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
    23221 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
    23281 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
    23341 tactacaagt ctaaaacgaa atttaagact tttcctcata aatactggtt tattttggtc
    23401 tcatgtaaaa ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt
    23461 ctttcatttg gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata
    23521 aactttgcgt aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc
    23581 caagcatttt cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga
    23641 atccaagaat gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc
    23701 tgaagtccgc aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga
    23761 taattccttg attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga
    23821 acaacagatt gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt
    23881 ctaatccttt aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt
    23941 gtttgatgat ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga
    24001 aattttttgc ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac
    24061 caactacaaa taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt
    24121 cttgagctgt gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt
    24181 gtgtaggata caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat
    24241 acatttggat ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt
    24301 aaggtgcttg tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag
    24361 aaaacagata gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc
    24421 caaataattg aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg
    24481 caattccatc tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga
    24541 tcgaaccata attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca
    24601 aatacacggt caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat
    24661 attctgtttt attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt
    24721 tgctcagcta cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct
    24781 tcatcagata attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct
    24841 tgcggagagt ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt
    24901 tccaactctg ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt
    24961 acttgatttc ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta
    25021 tccacgctac tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt
    25081 ttagagtgag gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt
    25141 tcatcgtaat acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca
    25201 cgtacttgtc gttccttcac gatattcact tgaggttggg tataaaacag atctggataa
    25261 actgtttccc gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca
    25321 acatcgccga caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac
    25381 gctagcgaac tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt
    25441 tgttccgggc tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta
    25501 tcttccttca aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac
    25561 tgatcaaact gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc
    25621 gcttgagaaa aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg
    25681 tttagccaat gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc
    25741 tctgcaagtt gcgcacttaa ctttgtctga tccggataat tcaaactatt tgtttccaac
    25801 atgctgctga gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg
    25861 ataaaaatcc ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct
    25921 gccaattgat acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt
    25981 taatgggtca acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa
    26041 ttcgccgttt tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa
    26101 aagaaacaga cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa
    26161 agacaaataa aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg
    26221 tggagatgtc ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt
    26281 aaaccaagtg gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac
    26341 aggtacttct gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt
    26401 cacatttgcg tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt
    26461 cttattctta gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca
    26521 agtggaagtg gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct
    26581 tgccaaacaa gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac
    26641 ttctaaataa taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg ctttcttttt
    26701 ttagattctt aacttgctac ttgttccttt ttcatgtcga tatgtggaat atcatcttcc
    26761 aaatacacat ctgagattgc cttgaatcca aacgactcat aaaaagcttg taggtattct
    26821 tgtgcgccga tcacgattgg tttttctgga aaatttttct ggatcatgtt aatcgtttct
    26881 tgaacaatct ttcttcctaa accatcttta cggttgtcct gatgaacaag gacacgtcca
    26941 aaatggatac tctccgcttc ttcatatact cgcgtgtagg caaggatctt cccatcagta
    27001 tcttgaaaaa acgtatgcca agcttgtcca tcaatgtcat caacttcttg ataaggacac
    27061 tgttgttcca caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa ctctgctgtt
    27121 gacaattctt caaatttctt tacctgatat tccactaagc aaacgccccc tgctttttta
    27181 ttcttagcat accgattcgc acacaaaaaa gcaaacgaac cttacgaatc t
//
LOCUS       DAZKPE010000036        26159 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000036 DAZKPE010000000
VERSION     DAZKPE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.036"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(61..1092)
                     /gene="queA"
                     /locus_tag="ACG930_001672"
     CDS             complement(61..1092)
                     /gene="queA"
                     /locus_tag="ACG930_001672"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFQ0518833.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1285..2460
                     /locus_tag="ACG930_001673"
     CDS             1285..2460
                     /locus_tag="ACG930_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0518834.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2464..3105
                     /locus_tag="ACG930_001674"
     CDS             2464..3105
                     /locus_tag="ACG930_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518835.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3102..4019
                     /locus_tag="ACG930_001675"
     CDS             3102..4019
                     /locus_tag="ACG930_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0518836.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4016..4687
                     /locus_tag="ACG930_001676"
     CDS             4016..4687
                     /locus_tag="ACG930_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518837.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5228..5716)
                     /locus_tag="ACG930_001677"
     CDS             complement(5228..5716)
                     /locus_tag="ACG930_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFQ0518838.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5917..6183)
                     /locus_tag="ACG930_001678"
     CDS             complement(5917..6183)
                     /locus_tag="ACG930_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFQ0518839.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6183..6446)
                     /locus_tag="ACG930_001679"
     CDS             complement(6183..6446)
                     /locus_tag="ACG930_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0518840.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6967..7107
                     /locus_tag="ACG930_001680"
                     /pseudo
     CDS             6967..7107
                     /locus_tag="ACG930_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(7249..9072)
                     /locus_tag="ACG930_001681"
     CDS             complement(7249..9072)
                     /locus_tag="ACG930_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0518841.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9670..12375)
                     /locus_tag="ACG930_001682"
     CDS             complement(9670..12375)
                     /locus_tag="ACG930_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFQ0518842.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12681..13628)
                     /locus_tag="ACG930_001683"
     CDS             complement(12681..13628)
                     /locus_tag="ACG930_001683"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFQ0518843.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13818..14087
                     /gene="rpsN"
                     /locus_tag="ACG930_001684"
     CDS             13818..14087
                     /gene="rpsN"
                     /locus_tag="ACG930_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFQ0518844.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14263..14625)
                     /locus_tag="ACG930_001685"
     CDS             complement(14263..14625)
                     /locus_tag="ACG930_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0518845.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14636..15757)
                     /gene="alr"
                     /locus_tag="ACG930_001686"
     CDS             complement(14636..15757)
                     /gene="alr"
                     /locus_tag="ACG930_001686"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFQ0518846.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15773..16123)
                     /gene="acpS"
                     /locus_tag="ACG930_001687"
     CDS             complement(15773..16123)
                     /gene="acpS"
                     /locus_tag="ACG930_001687"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFQ0518847.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16253..17764)
                     /locus_tag="ACG930_001688"
     CDS             complement(16253..17764)
                     /locus_tag="ACG930_001688"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0518848.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18086..19438)
                     /gene="murF"
                     /locus_tag="ACG930_001689"
     CDS             complement(18086..19438)
                     /gene="murF"
                     /locus_tag="ACG930_001689"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFQ0518849.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19591..20667)
                     /locus_tag="ACG930_001690"
     CDS             complement(19591..20667)
                     /locus_tag="ACG930_001690"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFQ0518850.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20863..22608
                     /locus_tag="ACG930_001691"
     CDS             20863..22608
                     /locus_tag="ACG930_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFQ0518851.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22888..23325)
                     /locus_tag="ACG930_001692"
     CDS             complement(22888..23325)
                     /locus_tag="ACG930_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFQ0518852.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23309..24682)
                     /locus_tag="ACG930_001693"
     CDS             complement(23309..24682)
                     /locus_tag="ACG930_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518853.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLELSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25004..25492)
                     /locus_tag="ACG930_001694"
     CDS             complement(25004..25492)
                     /locus_tag="ACG930_001694"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518854.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25514..26116)
                     /locus_tag="ACG930_001695"
     CDS             complement(25514..26116)
                     /locus_tag="ACG930_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0518855.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5559 c         4838 g         8259 t
ORIGIN      
        1 tttgtcataa aatctttgta aagctttttt gttattcaaa actagcggct tttcataacc
       61 ttatttcacg aacatcgcat ctccaaaact aaagaaacga tagcgctctt caatcgcatg
      121 ctggtaagca gataaagtca attctcttcc tgcaaaggca ctaactaaca tgactaaagt
      181 cgattttggc aaatggaaat tagttgagaa agcttctacc actttgaatt catagccagg
      241 cgtaatgaaa atatcagtcc atccgctgtc tgctttgatt tctccattaa atttcgttcc
      301 aatcgtttct aatgttcgaa ttgaagttgt tccgacagcc acgattttcc cgccattttt
      361 acgtacttgg ttcaatcgct cagccgcttc ttccgtcaaa cggtagaatt cactatgcat
      421 atggtgttct tcaattttat ctacgctgac aggtcggaat gtacctaacc ctacatgtag
      481 tgtcagatag actaattcaa caccctttgc ttcgatctca tcaagtaatt ctttcgtaaa
      541 atgcaatcca gctgttggcg ctgcagcaga accattttct ttcgcataga cagtttgata
      601 gcgatctggg tcttccagac gttctttgat atatggaggc aatggcattt ctcccaatga
      661 ttcaagaatc tctagaaaaa ttccttcata ctcaaagtca atgatccgtc cgccgtgttc
      721 caattcttct ttcactactg cttgcaatct gccatcacca aaagagattc ttgtcccaac
      781 tttggcacgt ttcgcaggtt tgatcaatgt ctcccacgta tctccttgtg tattcgttag
      841 aagaaggact tctaaatgcg caccagtatc tggtttttct ccatataaac gagcaggcag
      901 aactcgtgta ttattcataa ctagcgcatc accaggctgt aactcttcaa tgatttcatg
      961 gaaatgttta tcttccatct ctccagtttt ccgatccaaa acaagtaaac gagaatgatc
     1021 gcggtctttt aatggtgttt gtgcgattaa ttcttccggc aagtcaaaat caaaatcttc
     1081 tgttgttaac atatcgtcac tcactttcta tcatgtgctt catcattcta tcatgttttt
     1141 cgttctgttg gcaaaatcag cactttttca cttctatttt ttgttttcct aaataaaaaa
     1201 actaccctat ttgtattttt tcattgtttt aggcatacta gtaatagata gttcttcatt
     1261 gaaaatagaa aaagaggtgg caccatgatt gaatttcaaa atgtgtcaaa aatttataaa
     1321 ggtggaaaag tcgctgtaga ggacgtcaat ctttcatttg aaaagggtga gttcatttgt
     1381 tttatcggta cgagcggaag cggaaaaacg acgacgatgc ggatgatcaa ccgaatgact
     1441 gatccaacac aagggaaaat tttgattgat ggaaaatcca tccaagaaat tgatccagtg
     1501 gaattgcgac gtcagatcgg ctatgttatc caaagtattg gattgatgcc tcacatgacg
     1561 atccgtgaaa atatcactct tgtccaaaaa ttgttgaaag tcagtcaaga agaacggaat
     1621 aaaacagctg aaaaaatgat tgatcttgtg gaattgcccc gtgagatgtt agatcgctac
     1681 ccacatgaat tatctggtgg tcagcagcag cgtattggag tcgttcgtgc ccttgcagcg
     1741 aatcaagata tcatcttgat ggacgagcca ttcggtgcgc ttgatccaat cactcgtgat
     1801 tccttgcaag accttgtcaa agatttacaa gagcgtttgg gaaaaacgat cgtatttgta
     1861 acccatgaca tggatgaagc gattaaacta gcaagccgta tcgccatcat gagtgaaggc
     1921 cgtgtgatcc aatttgatac accagaaaat attttacgtc atcctgcaaa cgatttcgta
     1981 gaagagttga ttggagaaga tcgcctacta caagccaagc caaatgcgac aagagtcggc
     2041 gaagttatgc taaatacagc aatcacgatt acaccggaaa aatcattaca agaagcaatc
     2101 aaactgatga gggaaaaacg tgtagatacg ttgttagtta ccgataattc gaatgtatta
     2161 aaaggattta tcgatgtaga aacgttgaat aaaaaacgag gaaaagtatc cagtgtcggc
     2221 gacattttga ataaacatgt tttttacgta aaagaatccg cctatcttcg tgataccttg
     2281 caacgcattt taaaacgcgg gctgaaatac gtgccggtcg ttgatgaaca gaacaaagtc
     2341 gtaggtatcc tgactcgtgc atcattagtg gatatcgtct acgatgtgat ttggggagaa
     2401 gatcccgcaa ctactgatgt tgcagagtca gctactcctg aagaatctaa ggaggtctga
     2461 cctatgcagc agttttttca tcagcacggt tcagaaattc tctcaaaagg ttttgaacat
     2521 ctttatattt caggacttgc tttgatcatt ggtatcatca ttgctgtacc gcttggtgtc
     2581 ttactgacac gttttccaaa agctgccacg attgtgattg gcttaaccag tgccttgcag
     2641 acaatccctt ctcttgcttt attggcattg atgatcccgc tatttggcgt aggtaaatta
     2701 cctgcgatta tcgcactctt tatttattca ttattgccga ttttacgtaa tacgtacatt
     2761 gggatgaaaa atgtcgattg gaattatcgg gatgtggcaa aaggcatggg gatgactgag
     2821 ttccaatcca ttttttccgt tgaattgccc attgctatgc caacgatcat ggctggtatt
     2881 cgtttagctg ccgtttacgt gattgcatgg gctacacttg cctcttatat cggcgctggt
     2941 ggtttaggcg atttgatttt tagtggactg aataattacc aaccagatct cattttggca
     3001 ggtacgatcc ctgtaacaat tttagcacta ttggctgatt ggcttctagg tctcttggaa
     3061 caccggctga caccgatcgc acttagagag gagaatgaag aatgaaacgt atactaaaaa
     3121 tgaccatggt tcttttctct cttcttatac ttgcgagttg ttccttccct ggtcttgcca
     3181 gcaatacaga tgaagacacc atttcgatca caggtggaat cacttcagaa gcacagatct
     3241 tagcaagtct agttgccgga atggttgaac attatacaga taaaaatacc gcaatcatca
     3301 acaatctggc tactacaact atcaaccatc aagcgatgat gaacggagat gcttcaattt
     3361 cagcggctcg ctacacagga acagatttaa cgactacatt gaaccttcct cctgaaaaag
     3421 atccgaaaaa agcgtttgct accgtgaaag atgaatttga gaaaagatac ggtcaaacgt
     3481 ggttcccgtc ctatggtttt gaaaatacgt atgtctttct tgttcgaaaa gacaccgcac
     3541 aaaaatacca tctatctaaa gtcagcgatc tgaaaaatgt agcggatgaa ttagtagctg
     3601 gtgtagatac ttcttggatc aatcgtaaag gagacggtta tgacggcttc caagaaactt
     3661 atggcttctc cttcaattcg atattaccta tgcagattgg acttgtttat gacgcagtcg
     3721 aagcaggaaa aatggatatt gttcttggct actctacgga tggacggatc gccagttatg
     3781 atctagtcat gttggaagat gatcgtcaat tcttcccacc atatgatgct gctccagttg
     3841 tagacaacaa gatattagct gatacgcctc atttaaaaga agccttaaat aagttaggtc
     3901 ataccatcag tacggaaaaa atgcaggaat tgaactacga agcagataat aatctagtgg
     3961 aaccatcagt agtagcacaa cgtttcttac aagaaaacca ctattttgaa gggaagtgaa
     4021 gcaattggat aaaatgaatg tctttcaaca atttttctat tatttccagg aaaatggctc
     4081 ctatatcttt gcacaattta tccgtcactt cctgatttct atctatggtg tcctctttgc
     4141 agcagttgtc gggattccgg ttgggatcat gatttctagg agacgtaaat tagcaaactg
     4201 ggtgattcgt ttggcgaata tcatccagac gatcccttct ctagccatga tctccatttt
     4261 aatcattgga ttaggcctgg gagtcaatgt cgtgattgtt actgtatttt tgtattccct
     4321 cttaccgatc atcaagaata cgtataccgg gatgatccaa gtagacaaaa acatccttga
     4381 tgtcggcaaa ggcatgggga tgactgctag acaacgacta ttcatggtag agttaccact
     4441 ctctgtttct gttatcatgg caggcataag aaacgcgtta gttgttgcca tcgggataac
     4501 cgcgatcggt gcattcgtcg gtgctggtgg tcttggagat atcattatcc gaggaaccaa
     4561 tgcaacagag ggcacatcga ttattttagc aggtgcattg ccaactgcat taatggcgat
     4621 catcacggac tggcttttag gtattttgga aagacggcta gatccagcca gccgtacatc
     4681 acgctgatgt tattgtaaaa aacaaaagct tctgcgacca tttgttggtc gcaaaggctt
     4741 ttttagttct gtcattttta aggcaataat ccactctgat tcttccctcc ttatgggcaa
     4801 agagttgctt ttcttagcta tttatccatt ccgtatactc caacttcata ctgccaacgg
     4861 gttcatatct gcatccaccg actaagtttt tttcttatcc gctaaggcat tttgccaatc
     4921 cattttccca tcactcgtca tggaattcat accacatgat ctctaaatac tcgtctgctt
     4981 gttctttgaa ttgggcatca attcttacat cctttggcgt ggctttcatt taagcctttt
     5041 ccatcagtcc tcgattgttc gatgccttca gctgcatcat caaaactggt gactgccgta
     5101 tcggtaactt cgatcatctt ttatacaatc gggaacttgc catcctcatc cttggctaaa
     5161 aacatatcta gccattccag cttctcgcca tgggaggttt gcggttccta aaaccggtac
     5221 acgattctta tggactgcat ccgtcgcaac tagacttggc gatacgatga tccttcacca
     5281 gaagagcacc cccgtaaacc aattgatcga tatattgcca ataagaaaag acattggcgt
     5341 aaaagatatc gatccctcgt gatgcattgc cgttgatact gctattcatg gccgaaagcg
     5401 ccacgacttt aacttcttcc gtttgagtga cattcatgtt cggcaatgtc gctttggata
     5461 cccgctctgc taaaggaacg acactggtat tgtatttcgt atctgtatct tttccaaaag
     5521 accatgccaa cgaatcctct gggaaccaat aagacgactc cggttgattg tccattgctt
     5581 ttttcaacat acttttggct gtttctcgat aaacgacatt tccaattgtc ttcgcctcac
     5641 tttggcgata atcgatggtc gttgccactg ccaacactaa caacgatgct ccaattttac
     5701 tgattttcct tgtcacactt cttcctcctt gttttacata aacccgtcaa cattccattc
     5761 ctaaactcaa acaatgaccc ttcaaaggtg gagatatagg aacaaattaa agaaatcatg
     5821 caataaatcc aagaaggttg gttttagaac aaaaaaagag tctccttttt ggggagactc
     5881 tttgttaact atctaaaaag gttggctctt ctcacttcac tcataatgtg tccaggcaga
     5941 ataaatttct acaactttat tttcctcatc aactttgtaa accactcgat gctgtctatt
     6001 cagcctgcgt gagtatctgc cttcatgtgt aggtctcagc ttttcaaaag actgcgtggg
     6061 catatatgga tcttccttca atgtctgaat cacttcttca aattgtttct ttaaattcgt
     6121 ttgcttgatt tttcttaaat ccactttcgc agagtttttg attgcgactg tatagttact
     6181 catcaaagag cttcccaatc aatatcatcg atattcgtaa agctactgtc gtctttttcg
     6241 cggtctcgta ctttatctaa agtacctgtt tgctcaagaa aaagggtttc ttgaatcgct
     6301 ctccagtctt ccagcccaat caatacagca ttgtttccac tacgatcact aataatctcg
     6361 atttcagtat gattttcatt tacctctttc aataactgat aaaaattttt acgagcagtg
     6421 ctaggattca tcgttgtatt agccattgtc tctcctcctt tttctgatat aattatagcg
     6481 tacttgatta agtacgtcaa aaaaatacaa taaagcactt aaattcagca aacttttcct
     6541 cttttttaca tagagaaaaa gacccctttt tagggaggat ctttgtccac gctcacttct
     6601 tactccttta cgactagcgg tagccaaacg taaagtaatt ggtaacaacg tatcatcttt
     6661 agcaaaggtc gaatccaaag cctgtgagtc tatgcaacaa caccaataca cgaaggttcc
     6721 tcgttgcagt gtgacttgat tgatatcttg aataacctga ggatacgcac gaaagatttg
     6781 taacggttat tcaaaactga ttttggccgt caagtcttct actgcctcaa aaatgattgc
     6841 ctctttcgtc tcctgtcatt catgttcact atcgatttga tacttgctta gaccgttggg
     6901 tttgtgaatc accaattaaa aatggcactg agttatggta acaaaaaatg gtcacttgac
     6961 gaggctgaga ttcctactta tgaagacaca tggcacttaa gagtcgaggt aaaggaagaa
     7021 gctgaaaata taggaggctg tacattattt ggcaaaggat tcggaaatta tgatcaagac
     7081 atcaaaatca aaatgtttta cagctaaata ggaagaataa taacatttca tacgctgttc
     7141 ccatctttaa tggcttatag agggcacctt tagctgagaa taagacaaaa cagaccctct
     7201 agcttcaatt aagagctaga gggtctgttt ttgattttaa aacttggttt atttcttcaa
     7261 atggtagcta taggtgctga caacgatatt ttcacgccaa gacaatcgca atcttaaccg
     7321 caaacttgtt tggttatgga gaatattctg ccagcgtctg tttggtacaa attgaggaat
     7381 caacacagta gttgtatagt tttgtttcgc tgcattttta cttacgatat ctacataacg
     7441 gataattgga ttttcaatcg agcgataaga agagtggacg attgaaaaac ggacatctgg
     7501 gaaatgcttt ttaaattctg cttcgatttc tttttctttt tcgacatctt cgtctagcga
     7561 aacatgcatc gcaacgacat aatcaccgat cgaacgtgcg taattcaacg caccgatatt
     7621 tacccgtgtc acattcccga ctaatacaag aacggtattc ccgtcataat catgtagttt
     7681 tgcatcattt tctaaacgaa gctgttctgc tactttttta taatgatcat ggatcttata
     7741 aaaaatgaac ataacgattg gcataatgat gaagaaaggc caaatgtccc ctaaccgata
     7801 gacaaacaaa atcgcaatga ttgcatatga gatgaacgca cccgtaatat tggcaatcga
     7861 tttgcttaac catctttttc cttctttttt ccatttgacg accatccctg tttgagataa
     7921 agcaaatgga atgaacacgc cgatagagta taacggaatc aagcgttctg ttgagccatg
     7981 gaaaataaac agcaatacga tcgaacctag cgctagtgtg ataatcccat tggaatagcc
     8041 tagtcgatcc ccacgatctt gatacatgtg aggcatgaat ttatcttttg ccagattgta
     8101 tgcaagaact ggaaaagcag aaaaaccggt gttagcagca actgctaaaa tcagcgctgt
     8161 agcaaattga aggacgtaat acaaaatacc atgtccaaag acagctttac caatttgaga
     8221 caaaacagtg acttcttttt caggaacgat cccataccaa tagttgataa atgtgatccc
     8281 cacgaagaag aaacctaaga tcaatgccat catcgtcaat gtagcagcgg cattttttgc
     8341 tcttggcttc ttaaagaatg gtacagcatt actaatcgcc tccaccccag ttaaagagga
     8401 agaaccagaa gaaaatgctc gtaaaatcaa agcgatagaa acacccggca cagccgctcc
     8461 tggaagtgca gtagcttgca atggcacagc acctgtcacg atattatata aaccaacaac
     8521 gatcagtaac gagatcacaa ggataaatgt gtacaccgga aataatagga acgatgcaga
     8581 ttccctcagc ccacgaagat tcagcatcat cagtagcaaa acgattgtca cagaaatagc
     8641 gacttgatga ccgtagagtg ctggcaccgc tgatgtgatc gcttcagcac ctgctgagac
     8701 agatactgct actgtcaaca tgtagtcgat caataaagag ccaccggaaa tcaagccagc
     8761 attctttcca agattctcac tgctgacgac atatgctccc ccgccatgag gataagcatg
     8821 gatgatttga cgatatgata gcgttaatga aatcaataaa ataataacaa aagcggcaat
     8881 gggtagcgaa taccagatgg ctgcagcaga caaagcgact aaaacgacaa cgatttgttc
     8941 cgtaccatat gcaatagatg ataacgcatc agacgacaat aatgccaaag cagcaaatcg
     9001 ggttaatttg tgctcatcat tttcagcaga ttttaaaggc ttacctacta acaacctttt
     9061 taagtaatcc aatttctaaa ctcctttaca cacaatttta cttcaagttt tatagtcgaa
     9121 aatttatagt aaacaagatg ttatagtacg ctcactgacc ttaaaagtca ataaacttta
     9181 agaaaataat tggaaaaaaa cagaaaaata tcaagcgctt tttcaaacgc tttaatacag
     9241 caaaaatcta acattttttt atgggctttt tctttgaatt ctataataaa aggatagaac
     9301 ttgacttaga aaatcaagtt ctatcctttt tgatatctta acttttggaa gagagatgta
     9361 aggctgcttt ctacccatca ttcttactac tcgaagcata gcgcagttgt cacaacctct
     9421 tgataaacgg tgtttaaaag cttgcatctg cggtaataag cccaaccaaa ttaaaaacat
     9481 aagaagctgt ttttatttgg tcgttcttat tacttgatgc agagcagctt ttttacaacc
     9541 tcttggtaca cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa acggcaaaat
     9601 atgaggaact atttttccat ttttttctct aatactcagg tcaaaacact gatttcacaa
     9661 cctctttttt taatgaaaaa tatggctctc atgcgccgct tctttgaatt tcgtcatttt
     9721 ttcttcgatg aacggataga ttgccgttcc tacgattcca aagacaacaa acaaaccgat
     9781 catgatccag attgctttcg tagcatttgg ccaataaatt cctcctgcag attcccgtaa
     9841 caagtttacc gcatgagtaa atggcaagaa cggattgatc atttggaaga atttccctga
     9901 gacttggatc ggatagttcc cgcctccgcc agagatcgac agtactaaga tgataatagc
     9961 gatcccttta ccgacattat cgaataatgc agccaagaca tagacgatca tcatgaacgc
    10021 taaggcgatc aagacagcaa atgacacgct gtagaccgga ttttggacat ctactcctag
    10081 taagaaaata ttccctaatg taacgatcaa gctttgcgca atcgccattg tcaaaaatgt
    10141 cagcatacga gcaacgaatt gttctcgttt cgtaaaattg tttcggtctt tctttcctaa
    10201 atagtattct gtcgtagcaa cacttgaaag aagaacagcg ccgacccaca gacatagtgc
    10261 agtataaaac ggggtgctag ctgaaccgtt atttgcgatt ggataaagcg cattggtttg
    10321 tagctcaaca ggttgtgtaa agaagtcact ttcttttgtt gcgtctagtt tcaataattt
    10381 gatgacttcg cctagatcga cttcttgttc gccttttcgg atcgcgtctg ctgctttttg
    10441 gataccagct ttgatatttg gccagtcatt gttgatcaag tccgcagcag cgttcacagc
    10501 tgtttcgact tctggcattt tttcatttac tgttgtcaat gtaccggtga tttcattttt
    10561 tagtgctggc caatcatttt ggataaaatc agcggccaat cctaattttt gctgaatgat
    10621 cggtaattca ttgttgtata ggtctgcccc ttcattgatg ccattgacga tggtatccat
    10681 atttccattc agcattgtat tggcatcatg gatttcttgt ccaattgcag gcatttcttt
    10741 ttgatatttt tctaaaattg ccactgcatt cgttacagtt gctttcgttg agctgagaag
    10801 cgaatcaaag tcgatctggt ccgctttgct cagtgcgcct tgtgcagtcc caatcgtatc
    10861 gatgacttgg tctagtagag aagtgacagt ggaactgatt tgacctgtat tgataccagc
    10921 aatgatgcca ttgatattat taacaacggc atcaatttga tctagcaatt catcaatagc
    10981 cttcgtgtct tcattttgaa cagctgtgtt caaagcagat aggcggtttt gcagattgct
    11041 tagcaagggt tttaattgat ttagctgatc aataattggc tgtaatttcg tatttccagc
    11101 acttgtttgc aatttagtca ggaactcgac cagtttatcg attgcatttt gttgttgaga
    11161 tattccgtca ataaagccgt tcaatacatt gctgatgttt ttcttttcat catcagtcag
    11221 cttaccatct tcaatagctg ttcttacagt atctattaac gaacctgtcg ttgttgccac
    11281 ttgtccaatt gacttcaatg taacatctac actgtttgtg atgcttggta tcgcatcttt
    11341 cagctgagag gcacctgatt ttgtttggtt tgctagatca cttgcctgat tttctaaatt
    11401 tttcacatct ggcaagatat cttgtacttg ttggatgatc gtcaagcctt gttttgcttc
    11461 atcgattcct tggttcattg tctcttggat cgaagcaaaa tcgccgtcga tctctgctag
    11521 ttgcttaccg gcattttgga tctctgggat tttttcttgc aaatcaagga tgatttttgc
    11581 ttgatctttc aactcaggca ttttgtcatt caatgcaacg actttttcac ccatctcatc
    11641 tactttaggg atgtaatcca cgaattcatt tgctttattc agtttttcct tgatttcagg
    11701 tagttgactt tgtaattcga ggacttgttt tgtgtagccg tcgatcgtgt ccaaattttc
    11761 atctgttgat aaaatcatat ctttaacttt attgatactt actaggttcg tatcgatgtc
    11821 gtaacctatc tcattgaata ctttcaataa agtcgaactg gctgttttga taaattcatt
    11881 tgtgatttgc gattggatcg aacttgctcc tttatcggtg attttcggtg caatcgcatt
    11941 gattttttca tttaccgtat attcgatttt tggtttcttg atatcaccac tagtaaaact
    12001 cagcagatct tctgagaaat cctttggcaa gtaaatacct gcgtaatact ttccggaacg
    12061 gactccgtct tctaattgtt cttttgaatc aacgaattgc catcctaatt gtttattttt
    12121 atgaagcgat tcgatgactt gctccccaat ggccacttct ttaccttgaa actctgctgg
    12181 cttgtctgca ctgtaaacag caattggcag ctctccagta tttccatatg gatcccataa
    12241 tgctttgatg ttaaaccacg catatagcga agggatgatc atgatcgcga tgatcagaag
    12301 tgttgcaatc gggtttttga aaatccgttt ccagtcaagc aaatataatc gaagcgtatt
    12361 tttgattgac tgcatagttc tcccccttct tcttttttca gctgaattac tttaccatgt
    12421 atttcatact tttttcaatc ggcttttttc aaaaaagtcg aatttttgga catatcacgg
    12481 caattgtctc attgtaatct cttacatatt gagaaataat taaggattac agcctttact
    12541 ttatcatgaa ataaaaggga aagataattt tatgccaaag tttttatcta ttatacgtat
    12601 acgcaaaaaa gctaaaacat tttttgtctt tgcccctaca aaaatgtttc agcttttttc
    12661 gttttttatt cctgtatttc ttatttttcg aatgacagga tgattttccc agcaggagga
    12721 tgtccttcaa ctagctgatg tgcttggatg acatgcttaa gtgaagcaga cagattcatt
    12781 gaaataaaaa catgaaaggc tcctttttgg taggctttga ttatgccagc aaaggcttct
    12841 gcatctagat attcctttct tggaacaaac gattcataaa agccttcctt tttttgccgc
    12901 aaatctagat ctgggaggtc atttaatgca acatacctgc cgcctggttt catgatctgg
    12961 atgccggttt ctcctttgat acttcctttc gtcgcatcga ttacaaggtc tgcctgatca
    13021 gcaaattgca gacctggatt tgttttatca taagcagcaa atgctgaagc tcctaatttt
    13081 tttacctttt cctcattttt actggatgca ctggttaaga ttcggattcc cttttcatgg
    13141 agaagctgga tcagacttga cccgaccgca cctgatgctc ctagtatcat tacagtatct
    13201 gtcggctgga tttccgtcaa atggttgatt agattataag ccgtaattcc tggcgtgacc
    13261 attccggctg cttcttccca actcatttta tctggaattt ttgctacttt tgctgatggc
    13321 aacacgactt cttctccgta agtcccgccg actgcatgga cagctactcg atcacctaca
    13381 tgaacagttg tgacatctga accaatctct gtcacaatac cagcgccatc attacctggt
    13441 acataaggga atttcaatgt tcgtatctct ttcatttctc ctaaacgcaa ggcaacatca
    13501 taaggattca cactgaatgc ttttatttct acacgaacat gtccagaacc gacttctctg
    13561 ggatgagcat cgatttcttc aaaaacatct tgtgcttctc cgtaaccgtt aattgcaaat
    13621 cttcgcatgg tcaccatctc cctttttctt taagtttacg tttatgcctt tattttgaca
    13681 aaaaaaatgt cttttcgttt tggcgcatga ttcaaaacaa aatagttgtc ttttttcgcg
    13741 taacgtgtta aattatttat ctaaaagcgt aaagattacg atttacgcta ataaaaaata
    13801 attggaggaa tttgttgatg gctaaaaaat caaagattgc caaagcaaaa aaacagcaag
    13861 aaacgattga acgctatgct gctttacgcc aggaattaaa agcgcaaaaa gattacgaag
    13921 gcttgcgtaa acttccttta gatgctcgtc cagaacgatt gaaaaatcgt gatttaatcg
    13981 atggacgccc tcgcggatac atgcgtaaat tcgggatgtc ccgtataaaa ttccgtgaat
    14041 tagcacataa aggtttgatt ccaggagtaa aaaaagccag ctggtaatcc aagtctggct
    14101 gtaatgtaaa ggaggagggc gcatggacca ctccttggat catcaaaaaa gatacgttcg
    14161 cttcttctag cagaaatgct ggtactagaa gcagacgtat ctttttttac gcacagctgg
    14221 tcctttttta tatgtaaagg ctgcatggtt acttcgctat atttatttag taacaggagt
    14281 cagtgcttcg atacccacac taattttcaa tgctcggtca acttctgcca taatgggtcg
    14341 atccaaatgg cagacctttt ctttcaatct tgatttatcg atcgttctga tctgctccaa
    14401 caggataacg gagtctcttt ctattcctgt tccagtagct ttgatcccaa tgtgagtcgg
    14461 aagcttaggt ttagccattt ttgccgttat ggccgcaaca atgatcgtcg ggctaaaatg
    14521 gttacctaga ttattttgaa taaccaaaac tgggcgtgtt ccgccttgct ccgatcccac
    14581 gactggagaa agatcagcaa aataaatatc tcctcttttt accataggat cctccttatt
    14641 cttgatattc tcttggtatc cgctgtccta atccgcaagc cacttcatag tggatcgtac
    14701 ctaattgatc tgctatatcc tgcatagtga tttctttgtc tgcatttttg ccgataagcg
    14761 tcacttttgt tccgacagga aattcttgag gcaatcggat catcagttga tccatacata
    14821 cacgcccaat cgtttcacag tagttccctt ctaccaatag agaaaaaccc tgcatctttc
    14881 gtggccagcc atctgcataa ccgatcggta tcgttccgat ccactctgct tcaggagtga
    14941 tatatgtttc tccatagccg attccttcac ctgctgggag ttttttgact tgaatcaatt
    15001 cagaaaccag ctcaagtgct ggctgcaatg gataaacttc cggtagtgcg tgcccagagg
    15061 gattaagtcc gtacattgct actccataac gaatcatatt gccgattgtt tcatcatgcc
    15121 ataaagccgt tgcactattg ctgacatgta catatcgagg aagttcggga agttttttca
    15181 gcacttctat aaagcgttct ttttgcagat tccaatatgt atcatctgcc tgatctgctg
    15241 tagaaaaatg ggtaaataaa ccttcccatt ctaatacacg actttctttg atgaatgcag
    15301 ctgcctcttt tacttcttca ggtgtacaaa atccgatacg acccatccca gtgtctgctt
    15361 ttagatgaat cgaaagaggc gtctctagct tacttttctc taaaacagca gctgctgctt
    15421 gcaaccattc ccgtgtacct gcagttactg ataaatcatg agcaacagct acagtcagtg
    15481 cgtcgtaagg aaccatattc aagataagga tgggctgagt aaatccagct tctctcaact
    15541 cgactccttc atctaaattt gaaacacaaa agcccgaagc tccacctgca actgctgcct
    15601 cagctgtttc aatagctcca tgaccgtatc cgttcgcttt tactactgca aacaattctt
    15661 ttccttgcgg aagtcttgca acttcatttg ctacattttc agttatagct tttttatgta
    15721 tcactgcttt cgttgggcgg tgccaagcga caaccatcgt ttttccttct ttctagtctt
    15781 ccaaaataat ttgtgcaaaa gctgtttcat ttgtatgagt aatactgacc catacattgc
    15841 cttcatgagg tgaacgcgtc acaacaggct gaccattttc attttttaaa atctcgacat
    15901 cttgaaaggt aacttttccg atcccagttc cccaagcttt agagaaagcc tctttgcaag
    15961 cgtaacgccc gcctaaaaat tctacttggc gatgaaaagg caaggactgg aatagtttca
    16021 tttcatcaga ggtcaagatt cgtgcaatga attttggttt ttcttcgatc agccgagtga
    16081 tcctaggaag ttcgactgca tcgatcccaa ttccttttat catatgcttt tctcttttca
    16141 ataaatttag aacactctca ttctaccaaa ttataaccat tttgccacaa ataagtccac
    16201 aaataacaaa aatgaaagtt tctcttaaaa aagagaaact ttcattttat gtttaatcgt
    16261 tatttgaacg gattacaaat ccgcgttttt tatcattgtg acgtttaccg ccatcttttt
    16321 ggctgttatt atttttgcta taaccgcctt ttgatttgtt tccacgataa ttaccgccgt
    16381 cacgacgatt acggttgttt ccgccaccac gtttgccatt tttattgtat ccttttttct
    16441 gcattggcaa tgggcgttct ggtgtgatct tcactggcac tgcatcagct ggatcttttg
    16501 ctgtcgtttt tagcaaaagt gcaactaaat cttgtgcaga atattcttct aataatttat
    16561 ctgctgtttg caggtattta tctagaccat tttctgcaag ttttgtttcg atttgttcaa
    16621 ctgcagcacc taattgacct ttgaatgctt ctttttcggt tggtggacgt aaagtcgtca
    16681 tccgtttttt cgtcaagttt tcaatcacat gcaagtagtc catttcattt ggtgtaacga
    16741 aagtcacaga cataccgcct tttccggcac ggcctgtacg tccgatacgg tgaacgtagc
    16801 tttctggatc ttgagggata tcatagttgt acacatgagt gacacctgaa atatctaatc
    16861 cacgtgcagc aacgtctgtc gctacaagga tatctaaatg accgctctta aatgaacgca
    16921 atacgctcat tcgtttttgt tgagacaaat cgccatggat tccttctgca cggtaaccgc
    16981 gtgcttctaa tccgcgtgcc aattcgtcta cacggcgttt tgtacgtccg aagacgattg
    17041 ttaattcagg tgtttgaaca tcaaacaagc gagtcatgat atcgaatttt tcgtattctt
    17101 ttgcgcggac atagtattga tcgatcaagt cagctgtcat ttctttcgct ttgatcttca
    17161 catgatgtgg atttttcatg aatttaacgc caatattctt gatagctggc ggcatcgttg
    17221 ctgagaaaag taatgtttgt ctttgatcag gaacttgtga aatgattttt tcgatatctt
    17281 ccaagaagcc catattcaac atttcatctg cttcatccaa aactaatgtt tgaacggttc
    17341 caagtttcaa tgtgtggcgg ttaatgtggt caagcatacg tcctggtgta cccacaacga
    17401 tatgtggacg atctttcaag ccacggatct gacggccaat atctgctccg ccgtaaacgg
    17461 cttgtacacg tacttttttg tcgcgcccta aacgatataa ttcttcttgt gtttggatag
    17521 ctaattcacg tgttggtgcg ataactaaac cttgtaattc gtgacgatct ggatcgattt
    17581 tttctaacat tggtaatcca aatgcagctg ttttccctgt acctgtctgt gcttgtccaa
    17641 taacgtcttt tccagctaat gctagtggaa tcgtttctgc ttggataggc gttgcttctt
    17701 caaaaccagc gcgttcgact gatttcaaca attctggtga taattctagt tctttaaatt
    17761 tcaaatgaat cctcctatat ggttgttaac tgaggatgta gcttttttgc taccccgtcg
    17821 atttgttcgg tcaaagtgta ttgtttcttt ttgacagtgg ccacgcacgt ttttatccat
    17881 tcttagcccc tgtggcacca ccgaaaaatc actttgcgaa gtttaggcat tagaaaagcc
    17941 aaacgggtcg cgttcagctt tatcattatt atgacatctg gcttcaacaa gttgtttcta
    18001 tggcaaaacc agtccaattt ctcttcatct ttcggcaata ggttattcta acatagtttt
    18061 tcgttttctg caagtttaca gatttttatt tcatttgctg aagttgttct accacttcaa
    18121 ataagcccat gctgttgctg ccttttagca taatactatc tgttgcttca agattttgtt
    18181 tgatagcatc aatcaattta ttcttttctt tttccaaata gaacacaggt agttgggggt
    18241 atttttggtt caattcttct tttagtgcat gcatttgttc cccataaagg aaaatcatgg
    18301 cgaatttctc aggatcgata tgttcactca tttgcgcatg catatttaaa gactctttcc
    18361 ctaattccag catatctgct aacacagcga ttctgcgtcc ttttgttggc agatttttaa
    18421 aagtatctaa taccagtccc atggctgttg gatttgcatt gtagacatcg ctcaaaatag
    18481 ctgcaccatt tcctgccgtt agccattcgg ttctgttttg agtgatagaa acatgggcga
    18541 gcccttggcg tatctcaggt atggacagtc caaagaagcg cccgatcgta tacgcaatca
    18601 aagcattcgt tacattataa cttccaggca gcgggatcgt aaatgtttct ccttctacta
    18661 caaaatcggt ttgtgctttt ccttttgctg tcacttccgc atgaacatcg ccatttccaa
    18721 taccgaatgt tgtgactgtt tgtactaatg ttgccgttaa aggtgtcagc aacggttcat
    18781 ctgcgggcac aacgagtaat ccgtctgata caagtccgtc agtgatttcc attttggctt
    18841 tagcgattcc ttctcgcgac ccaagatttt ctatgtgtgc ttcaccgatc attgtgattg
    18901 ctgcagcttt tggttgagcc ataagtgaaa gttccgtgat ttcattggcg tgatccatgc
    18961 ccatttccaa aacgatcttt tctgtatctt ggggcatgtg caaaatcgtg taaggaagac
    19021 caatattatt gttgtaattt ccttgcgtct tatatgtttt gtatttttca gacaagacag
    19081 acgcggttag atctttcgtg gtggttttac cattgcttcc tgtaattgca acgacttctg
    19141 cgcctacttt ttccaagtaa taggttgcca attgctgcat ggctttcaaa ggatctgcta
    19201 caggaataac tggaaaattt tttggagctt gttcaacagg caagctccaa aatgaagcag
    19261 atgctccgtt tgtgatcgct tgctggataa attcatgtcc atctcgcgta ccagcaagag
    19321 gaacgaataa acttccttcg gttatcttcc ggctgtcaaa ttcgacattg gtaatctttg
    19381 tcagtgcaga gcattcgctg cccacggctt gtgcaatttc ttgtattgtt agattcattg
    19441 agatctctcc taaaaaaggt tgtgaaaaaa gcgtttggcc taaacggcgg gttcgcatga
    19501 ctctcacttc caagtaaatt tctctattcg tatttagaag ctagaatgaa cgcggttacg
    19561 caatcactcc agcctcttct ttatttctct ttattcattt ttttcaaaaa aagattgacg
    19621 ctgatggtat cgattcattc ctaactggat cagttcttca atcaaatcac cgtatttcaa
    19681 gcccatattt tcccataaga gtgggtacat actgaactcc gtaaatcctg gcatagagtt
    19741 taattcattc aggaataatt catttttatt tgtcaaaaag aaatcgcacc ggctcaatcc
    19801 gcttccacct aacatcgtgt aagctaactt cgcgtactct tgcgcttttt gataaacttc
    19861 ttctggcact tcggctggaa tctgcatttc gattttatta ttgatatatt ttgcttcata
    19921 atcatagaat gctacgtctt ttacgacttc accaggcaaa gtcgtccgaa cgtcttcatt
    19981 tcctaataca gcaacttcga tttcgcgcgc ttcaattcct tgttcaacga ttgctcgaga
    20041 atcatactga taggctgttg ctaaagcatt ttgcagctct tctcggtttt ctgcttttgt
    20101 aatgccgaca ctagaaccca tattcgccgg tttgacaaac atcggataaa gcaaagaacc
    20161 ttcacattga tcaaatactt ttttaggatt ttctttccat tgattcttaa gtactggtac
    20221 ataaggaact tgcggcacac cagcagcttg taaaatatac ttggtcatga ttttatccat
    20281 ggcacatgca ctggtcaata cgcctgcgcc gacataaggc atattcaatg tctctaagaa
    20341 gccttggatc gttccatctt ccccgtttgg cccatgtaaa actggaaaaa cgatggctcc
    20401 ttcttctttg atttcgcccg gattgatcac ttttcctgta aagccttcct ctgtctgtcc
    20461 acttgggtcc catgaaagat gcaagacatc tttgctggca ggtttttctg ttagtaatgg
    20521 acctttgacc cattgtcctt cttttgtaat aaatacgagt tgaacttggt aataattata
    20581 ataaatggca tttaaaactg aaaatgcgga aagaatggac acttcatgct ctgcgctgcg
    20641 tccgccatat agtaaagtaa tcttcaaaag attgtcctcc tgtattctaa atcgttcagt
    20701 gatttactct catattttag cacaaaacaa aaataaacga ataacttatt tataaaaaaa
    20761 cgagccagct tctaaaagaa cgagcgtcat ttattttttg tcagctagat tatttgtccc
    20821 gttttttata aaaagttatg ataaagaaaa ggagggatga tgatggcgca aacaaatcca
    20881 cgcagccgct tggcagaaat cattcgagtg ttcatcaatt acaatgtagt gccaaacttt
    20941 gtacagcaaa aaaatcccga acaggtaaaa aaagcctttg aagaactagg ccccaccttc
    21001 atcaagatag gacagatgct ttctgttcga gaagatttgc tttcttctgc cttcactcaa
    21061 acattcaaaa cattacaaga tagtgtacct agcgacacat tttcaacggt caaaaagacg
    21121 atcgaaacag aactttctct ttcattatca gatatattcg atgatttttc aaaatcgcct
    21181 tttgcctctg cttctatggg gcaggctcat cgtgccaagc tgaagaacgg tgacgcggta
    21241 gtcgttaaga tccaacaccc taacatcgcc gaagagatcc gacttgatct tcaactattt
    21301 gaacgagcga tccctttgat caaatacatt cctgaaacta gcgtagttga tctaaaaggg
    21361 gtactccaag aagtaaaacg ttccttgatc aatgaaatgg acttcttaaa agaaagtcaa
    21421 aatggcgaac aattctatca aaagaacaat ggctggaaag agatccgcag ccccaagatt
    21481 tatgacgctt tttgttcgaa aaaagtgatc gtgatggaag aaatgtctgg taaaaacttg
    21541 aatcatttaa tgaacgccga aaacaaaact gaaactttta tcactggaat tcaaaacaag
    21601 cagctgaaac aagaagttgc aaagctttta gttgagaact ttatgaaaca ggtgtttgat
    21661 gatggttttt tccatgctga tcctcatcca gggaatctgc tattccatgt actaacaaaa
    21721 gaagaacaga cacaagctag ccgaaaaact gaaacagtcc atgaaaaaga gttcggttcc
    21781 tttgcttttc gagcctccac ttctgcagaa gaccctgttg cgccatatac catcaactac
    21841 atcgattttg gtatgatggg gcatctttct gcaggactta ggcaaaaact cacacaagcc
    21901 gttttagcgc tgtatacgaa agatgcttat cgaatcgaaa aagcggtcct tcgactttgt
    21961 cagcaagaag gctcgtttga tgaaagtcgg ttccaccaag aactgacaag ttttcttgaa
    22021 cagtattatg attctcctat tgatgaaatc aacttgcaag aagtattcac acatgtcgtg
    22081 acgatttgtc atcaaaataa tctgcagttc gatcgtgata tcacgctttt gctgaaagca
    22141 tttgggacat tagaaggggt gatccgcgtc ctcgatcctg aagtttccct catggaagtc
    22201 gcttcgcctt ttgctcaaca ttattttctc actcatctgg atgtagaaga tacattgaaa
    22261 caaagcggat tagacttatt ggaagggatg aaggctgcgc ctaagatccc tcaacagctc
    22321 caccatctat tagaaatgtg gacttcggga caaggaaaag tcaatttgga attgaaaaag
    22381 caagacaaat tattgagcag gatcgaaagt atgatcaatc ggcttgtttt cggtatgatt
    22441 ttagctgcat tgatcgtagg gtcctccctg cttgtccaag cagcacctgt agaaaacgca
    22501 gaggtcgttt ccttattagg gatatttacg tatgctattg ccgcattcgt cattattttt
    22561 ttggcaatcg atgcattgat ccaaatgtat aagaagagga aaaagtagaa aaaggttgtg
    22621 acagaaagaa tcagcttcaa gaaataagaa ggggttttac ataaattgtt tctcaaattt
    22681 ttgtgaaaat tcggcttatt tttcgaagag gctacttctg aaacaccgag aataaaaaat
    22741 gtgaaaaagc tgttctgcac ccagtaataa gaacaatcaa aaagggaaca tggaacacat
    22801 ttatcctgtt tccctgttcc ctttttgatg tattcgagca taaataaaat accttcgtta
    22861 cctactatct tctgtacttg gtaaacctta gtcaattgcc ttttttaacg cttgacgaaa
    22921 agacatatga tctttctccg taaagggttt tggacccttt gtccttatgc cagcttttct
    22981 taactttcca ctatgataac gttgttctag aagcgtgccg atattcgctt cgtcaaattc
    23041 ttttccagag tgatggaaca ctcgcacacc cttcggcaat acaagtgaag ctaaaccata
    23101 atcttgcgtg atcaaaaagt cattcttctt aaccataccg acgattttat aatccgcact
    23161 atcagctccg cggtctacgt agacgatttg gacatgatta gcgtattctt tggtcgtata
    23221 atggtccaca ctggtcacga taaccacgtc aagaccatag gattctccta attttatgac
    23281 atcttctttt actggagaac catctccatc aatgaatagc ctcattcttt ttcgccttct
    23341 tccataaatg ataaacagtt actaatccgc tcagtaaaag accaacattg atccattttg
    23401 ccaagataag cagttgtaca ctttctatcg gcactgattc atggttcagc gtgatcaata
    23461 atagatggat tggctctccc atttcttttg ctaaaacaaa caaaagcgtc atcaataaaa
    23521 actggtggat cacactccct ttattttgag tagtatactt gacaacgatc cggcgatcca
    23581 ttggaatagc tgtatcagtt tgataatatt ccttatttag ccagctgcct gttactacgt
    23641 gccagaaact aagcagaaag acacctatcg caaaaccatt tggaatcaag aggaccaata
    23701 aagaagaact cagttcaagc aattgcatag ccaatggaga ccatgttaaa cgtttcaaaa
    23761 tccatggtcc gactattttt gctgcaatca agcctgctgc ataaggcaaa tacataaaaa
    23821 tcgaaagttt ttctaatccg tacagtatgc caacataaaa actgctaaat aaaaaaagga
    23881 aattccctag cattccattt agaaaagtaa acagatttag ccagcttggc aacttccatt
    23941 ccttcttctg gtgtcctaaa acaaacacga acaagatgaa cagcagcaag aaaccataaa
    24001 tagcaagatc aaaaagcctt tcatcgaata acaatcgggc atttctcaaa agaaacaata
    24061 agccaaagaa tatcaaaaat aaaacaagct ctcgcgtagc taccagattt cttttgatgt
    24121 ctttgaaatc cagttcgtaa cgcggataat gactaaccgt atggtaggcc atgacgtaaa
    24181 aaagtgtata aatagtaaag cttgctgcaa tctgagtcgg tgcaggcaac tcaatcgctt
    24241 gatacaggag aaatagccag atagctgcaa ataagtactt tttcccatcc atattgataa
    24301 aaccttgcgt cttttcgtga aaattgaccg tggtattagc aggtacaagc catgctgcac
    24361 tcagccctag caaaacactt gaaaaataaa ataaaggaaa ataaaatacg cctaatattc
    24421 caagcaatga accagcacca ccaatcagca gagcgatcat cagcaacgtg taactatcta
    24481 gaccaaatcg tagactgttg actaaaaata gtccagtcat ccgaaaggca taaaacagcg
    24541 taaatggcaa aatcgtcagc caattatgcg agtctgttag tcccaaaaat aaaagataag
    24601 gaataaaaat aaccgtgtta cttaagataa agggcgttgt ttgtgtaaaa ttacgcccaa
    24661 atcgtttgag tttttcgaac atgacaatgg ctccttaaac agtcttataa ctaatctgct
    24721 cttcgatttt agcattaaag gggaaataaa ccaattttac agaatatatt cttgtaaaaa
    24781 aaaatacaga aagaagcata agcttctttc tgcattttta cggtacttga ttactcaagc
    24841 agacaagccc ttctccacaa aagtcttgcc cgacacccct gcatccggca ggtgataaag
    24901 atagaaatca attatcctgt gcctccaaaa tcaattagga gctctgtaaa ccagagtcct
    24961 tctcgacccg tcgcataaat ttactttaac acagttccta tgtttatgcg agagcttttt
    25021 tcattttata atcgaccatt tgaaatcctt gaccgatatc tgaaataagt tcttctgtaa
    25081 tctcaaatcc ttcatgctta taaacctcga ttgcttgatg attcccctga ttcactcgca
    25141 aaaagatctc tctttccttt gtttgcgcag caagttcttc ataccagcga aaaactgaag
    25201 aagtcaatcc ttgaccacgt actttattta gcaaatataa tttacttaaa taaatttttc
    25261 catttatctc ttcataagca gtgtaaccga cagtcttttc ttcgcttttt aataaaaagt
    25321 aggacacacc ttctgtcagt tctttttgaa tctgtttttt tgactgataa gttttcagca
    25381 tgtaatccac ttgtttttga ccaatgatcg gcacaaaagc ttccggccat acttcttgta
    25441 tgactgccat cagctcatcc agttcatttt ctgttacttt tattttttcc atacacccac
    25501 gtcctttttt acattataaa tgaccttgcg cttgatggaa taaaaagagc atgatcatgc
    25561 tatacacacc caccgaccat ggtttcaaga aaatcacaat ctgcataaat tccctaaaag
    25621 ataatttcgt caaaccagct actagacaga tcaagtcgtc tggcgcaaag ggaagcagca
    25681 aggtaacaac tagtactttt ttaatatctt tcgtttttct tgtcagcaat tcatcaaatt
    25741 tctgatactt ttttggcgat aaaataagct ggacaaaggc tacgccatag taacggacaa
    25801 gcaaaaatcc gattgcttcc ccaatcacta ggccaataca actatataaa agcccaaatc
    25861 cattgccaaa catcagcatg cccgctactg aggagatccc tcccggcaaa ataggaatga
    25921 tcacttggat cacttgcaac agaacaaata tcatcactgc atacttgcca aattgctgga
    25981 taaacgcttg caaagacgtg ctcgatcgaa aaatcccatg atgataagca taaagaatca
    26041 acacaaagaa aaaaaacaga ccaataatgg gcatgatctg aagacatttt tgtaaaactg
    26101 atcctttttt agacatctat attccccaca tcttttttca tttattaaaa ctgcctcct
//
LOCUS       DAZKPE010000037        25820 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000037 DAZKPE010000000
VERSION     DAZKPE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.037"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(326..2707)
                     /locus_tag="ACG930_001696"
     CDS             complement(326..2707)
                     /locus_tag="ACG930_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFQ0518856.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2697..3344)
                     /gene="recU"
                     /locus_tag="ACG930_001697"
     CDS             complement(2697..3344)
                     /gene="recU"
                     /locus_tag="ACG930_001697"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFQ0518857.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3408..3947
                     /locus_tag="ACG930_001698"
     CDS             3408..3947
                     /locus_tag="ACG930_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFQ0518858.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4037..4456
                     /gene="gpsB"
                     /locus_tag="ACG930_001699"
     CDS             4037..4456
                     /gene="gpsB"
                     /locus_tag="ACG930_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFQ0518859.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4478..4845
                     /gene="rnpB"
                     /locus_tag="ACG930_001700"
     ncRNA           4478..4845
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG930_001700"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5054..6220
                     /locus_tag="ACG930_001701"
     CDS             5054..6220
                     /locus_tag="ACG930_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFQ0518860.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6266..7762
                     /locus_tag="ACG930_001702"
     CDS             6266..7762
                     /locus_tag="ACG930_001702"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFQ0518861.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7843..8526
                     /locus_tag="ACG930_001703"
     CDS             7843..8526
                     /locus_tag="ACG930_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0518862.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            9171..10361
                     /locus_tag="ACG930_001704"
     CDS             9171..10361
                     /locus_tag="ACG930_001704"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFQ0518863.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10463..11416
                     /locus_tag="ACG930_001705"
     CDS             10463..11416
                     /locus_tag="ACG930_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFQ0518864.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11485..12834
                     /locus_tag="ACG930_001706"
     CDS             11485..12834
                     /locus_tag="ACG930_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0518865.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(13017..13340)
                     /locus_tag="ACG930_001707"
     CDS             complement(13017..13340)
                     /locus_tag="ACG930_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518866.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13469..14632
                     /locus_tag="ACG930_001708"
     CDS             13469..14632
                     /locus_tag="ACG930_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0518867.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14702..16051
                     /locus_tag="ACG930_001709"
     CDS             14702..16051
                     /locus_tag="ACG930_001709"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFQ0518868.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(16096..16527)
                     /locus_tag="ACG930_001710"
     CDS             complement(16096..16527)
                     /locus_tag="ACG930_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0518869.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            16915..19557
                     /gene="alaS"
                     /locus_tag="ACG930_001711"
     CDS             16915..19557
                     /gene="alaS"
                     /locus_tag="ACG930_001711"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFQ0518870.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVSVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19757..20353
                     /locus_tag="ACG930_001712"
     CDS             19757..20353
                     /locus_tag="ACG930_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0518871.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20475..21623
                     /locus_tag="ACG930_001713"
     CDS             20475..21623
                     /locus_tag="ACG930_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFQ0518872.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21661..22074)
                     /locus_tag="ACG930_001714"
     CDS             complement(21661..22074)
                     /locus_tag="ACG930_001714"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFQ0518873.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            22153..22584
                     /locus_tag="ACG930_001715"
     CDS             22153..22584
                     /locus_tag="ACG930_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFQ0518874.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22683..22916)
                     /locus_tag="ACG930_001716"
     CDS             complement(22683..22916)
                     /locus_tag="ACG930_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0518875.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            23099..24769
                     /locus_tag="ACG930_001717"
     CDS             23099..24769
                     /locus_tag="ACG930_001717"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFQ0518876.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24916..25302
                     /locus_tag="ACG930_001718"
     CDS             24916..25302
                     /locus_tag="ACG930_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518877.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            25289..>25820
                     /locus_tag="ACG930_001719"
     CDS             25289..>25820
                     /locus_tag="ACG930_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518878.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYT"
BASE COUNT         8330 a         4515 c         5435 g         7540 t
ORIGIN      
        1 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
       61 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
      121 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
      181 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
      241 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
      301 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
      361 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
      421 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
      481 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
      541 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
      601 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
      661 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
      721 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
      781 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
      841 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
      901 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
      961 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     1021 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
     1081 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
     1141 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
     1201 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
     1261 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
     1321 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
     1381 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
     1441 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
     1501 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
     1561 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
     1621 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
     1681 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
     1741 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
     1801 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
     1861 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
     1921 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
     1981 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
     2041 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
     2101 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
     2161 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
     2221 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
     2281 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
     2341 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
     2401 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
     2461 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
     2521 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
     2581 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
     2641 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
     2701 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
     2761 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
     2821 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
     2881 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
     2941 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
     3001 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
     3061 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
     3121 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
     3181 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
     3241 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
     3301 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
     3361 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
     3421 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
     3481 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
     3541 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
     3601 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
     3661 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
     3721 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
     3781 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
     3841 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
     3901 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
     3961 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
     4021 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
     4081 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
     4141 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
     4201 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
     4261 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
     4321 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
     4381 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
     4441 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
     4501 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
     4561 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
     4621 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
     4681 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
     4741 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
     4801 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
     4861 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
     4921 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
     4981 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
     5041 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
     5101 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
     5161 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
     5221 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
     5281 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
     5341 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
     5401 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
     5461 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
     5521 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
     5581 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
     5641 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
     5701 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
     5761 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
     5821 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
     5881 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
     5941 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
     6001 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
     6061 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
     6121 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
     6181 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
     6241 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
     6301 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
     6361 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
     6421 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
     6481 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
     6541 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
     6601 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
     6661 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
     6721 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
     6781 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
     6841 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
     6901 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
     6961 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
     7021 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
     7081 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
     7141 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
     7201 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
     7261 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
     7321 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
     7381 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
     7441 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
     7501 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
     7561 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
     7621 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
     7681 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
     7741 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
     7801 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
     7861 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
     7921 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
     7981 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
     8041 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
     8101 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
     8161 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
     8221 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
     8281 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
     8341 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
     8401 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
     8461 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
     8521 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
     8581 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
     8641 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
     8701 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
     8761 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
     8821 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
     8881 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
     8941 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
     9001 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
     9061 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
     9121 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
     9181 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
     9241 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
     9301 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
     9361 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
     9421 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
     9481 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
     9541 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
     9601 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
     9661 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
     9721 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
     9781 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
     9841 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
     9901 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
     9961 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    10021 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    10081 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    10141 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    10201 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    10261 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    10321 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    10381 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    10441 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    10501 tggttcagag ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac
    10561 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    10621 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    10681 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    10741 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    10801 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    10861 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    10921 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    10981 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    11041 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    11101 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    11161 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    11221 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    11281 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    11341 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    11401 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    11461 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    11521 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    11581 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    11641 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    11701 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    11761 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    11821 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    11881 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    11941 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    12001 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    12061 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    12121 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    12181 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    12241 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    12301 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    12361 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    12421 ggaatgcgtc tcccttatgt tattgcaaaa gaaaacaacc tgccttttag caagctcttt
    12481 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    12541 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    12601 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    12661 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    12721 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    12781 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    12841 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    12901 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    12961 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    13021 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    13081 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    13141 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    13201 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    13261 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    13321 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    13381 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    13441 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    13501 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    13561 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    13621 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    13681 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    13741 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    13801 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    13861 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    13921 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    13981 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    14041 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    14101 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    14161 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    14221 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    14281 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    14341 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    14401 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    14461 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    14521 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    14581 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    14641 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    14701 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    14761 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    14821 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    14881 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    14941 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    15001 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    15061 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    15121 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    15181 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    15241 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    15301 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    15361 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    15421 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    15481 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    15541 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    15601 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    15661 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    15721 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    15781 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    15841 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    15901 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    15961 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    16021 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    16081 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    16141 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    16201 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    16261 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    16321 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    16381 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    16441 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    16501 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    16561 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    16621 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaattaa gtacgaaaag
    16681 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    16741 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    16801 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    16861 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    16921 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    16981 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    17041 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    17101 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    17161 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    17221 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    17281 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    17341 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    17401 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    17461 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    17521 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    17581 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    17641 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    17701 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    17761 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    17821 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    17881 gaacaagcat tcttatatcg tttagtctct gttgttgggg aaatcatggt aagttattat
    17941 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    18001 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    18061 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    18121 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    18181 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    18241 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    18301 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    18361 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    18421 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    18481 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    18541 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    18601 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    18661 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    18721 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    18781 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    18841 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    18901 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    18961 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    19021 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    19081 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    19141 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    19201 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    19261 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    19321 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    19381 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    19441 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    19501 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    19561 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    19621 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    19681 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    19741 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    19801 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    19861 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    19921 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    19981 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    20041 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    20101 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    20161 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    20221 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    20281 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    20341 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    20401 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    20461 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    20521 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    20581 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    20641 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    20701 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    20761 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    20821 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    20881 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    20941 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    21001 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    21061 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    21121 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    21181 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    21241 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    21301 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    21361 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    21421 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    21481 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    21541 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    21601 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    21661 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    21721 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    21781 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    21841 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    21901 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    21961 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    22021 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    22081 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    22141 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    22201 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    22261 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    22321 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    22381 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    22441 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    22501 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    22561 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    22621 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    22681 atctattcat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    22741 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    22801 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    22861 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    22921 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    22981 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    23041 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    23101 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    23161 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    23221 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    23281 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    23341 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    23401 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    23461 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    23521 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    23581 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    23641 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    23701 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    23761 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    23821 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    23881 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    23941 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    24001 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    24061 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    24121 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    24181 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    24241 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    24301 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    24361 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    24421 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    24481 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    24541 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    24601 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    24661 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    24721 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    24781 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    24841 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    24901 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    24961 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    25021 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    25081 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    25141 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    25201 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    25261 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    25321 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    25381 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    25441 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    25501 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    25561 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    25621 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    25681 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    25741 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    25801 ccaaaacgga aagtacacaa
//
LOCUS       DAZKPE010000038        25672 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000038 DAZKPE010000000
VERSION     DAZKPE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.038"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            171..515
                     /locus_tag="ACG930_001720"
     CDS             171..515
                     /locus_tag="ACG930_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFQ0518879.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="ACG930_001721"
     CDS             516..935
                     /locus_tag="ACG930_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFQ0518880.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1027..1377)
                     /locus_tag="ACG930_001722"
     CDS             complement(1027..1377)
                     /locus_tag="ACG930_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518881.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="ACG930_001723"
     CDS             complement(1343..2674)
                     /locus_tag="ACG930_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFQ0518882.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="ACG930_001724"
     CDS             2930..3496
                     /locus_tag="ACG930_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0518883.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="ACG930_001725"
     tRNA            3641..3728
                     /locus_tag="ACG930_001725"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4062..5036
                     /gene="bsh"
                     /locus_tag="ACG930_001726"
     CDS             4062..5036
                     /gene="bsh"
                     /locus_tag="ACG930_001726"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFQ0518884.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5361..7256
                     /gene="asnB"
                     /locus_tag="ACG930_001727"
     CDS             5361..7256
                     /gene="asnB"
                     /locus_tag="ACG930_001727"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFQ0518885.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7451..7897)
                     /locus_tag="ACG930_001728"
     CDS             complement(7451..7897)
                     /locus_tag="ACG930_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFQ0518886.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8125..8274
                     /gene="rpmG"
                     /locus_tag="ACG930_001729"
     CDS             8125..8274
                     /gene="rpmG"
                     /locus_tag="ACG930_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0518887.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8362..8880
                     /locus_tag="ACG930_001730"
     CDS             8362..8880
                     /locus_tag="ACG930_001730"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFQ0518888.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8957..9913)
                     /locus_tag="ACG930_001731"
     CDS             complement(8957..9913)
                     /locus_tag="ACG930_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0518889.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALREKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10079..10885
                     /locus_tag="ACG930_001732"
     CDS             10079..10885
                     /locus_tag="ACG930_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518890.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10882..11871
                     /locus_tag="ACG930_001733"
     CDS             10882..11871
                     /locus_tag="ACG930_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFQ0518891.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11868..12872
                     /locus_tag="ACG930_001734"
     CDS             11868..12872
                     /locus_tag="ACG930_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFQ0518892.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13004..13546
                     /locus_tag="ACG930_001735"
     CDS             13004..13546
                     /locus_tag="ACG930_001735"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFQ0518893.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13566..14264
                     /locus_tag="ACG930_001736"
     CDS             13566..14264
                     /locus_tag="ACG930_001736"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFQ0518894.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14285..14497
                     /locus_tag="ACG930_001737"
     CDS             14285..14497
                     /locus_tag="ACG930_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFQ0518895.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14497..15459
                     /locus_tag="ACG930_001738"
     CDS             14497..15459
                     /locus_tag="ACG930_001738"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFQ0518896.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15477..15872
                     /locus_tag="ACG930_001739"
     CDS             15477..15872
                     /locus_tag="ACG930_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFQ0518897.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16035..16400
                     /locus_tag="ACG930_001740"
     CDS             16035..16400
                     /locus_tag="ACG930_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFQ0518898.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16397..18208
                     /locus_tag="ACG930_001741"
     CDS             16397..18208
                     /locus_tag="ACG930_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFQ0518899.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18270..18437)
                     /locus_tag="ACG930_001742"
     CDS             complement(18270..18437)
                     /locus_tag="ACG930_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFQ0518900.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18685..19674
                     /gene="galE"
                     /locus_tag="ACG930_001743"
     CDS             18685..19674
                     /gene="galE"
                     /locus_tag="ACG930_001743"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFQ0518901.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19686..21170
                     /gene="galT"
                     /locus_tag="ACG930_001744"
     CDS             19686..21170
                     /gene="galT"
                     /locus_tag="ACG930_001744"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFQ0518902.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21194..22174
                     /locus_tag="ACG930_001745"
     CDS             21194..22174
                     /locus_tag="ACG930_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0518903.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22365..23087
                     /gene="tsaB"
                     /locus_tag="ACG930_001746"
     CDS             22365..23087
                     /gene="tsaB"
                     /locus_tag="ACG930_001746"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFQ0518904.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23071..23613
                     /gene="rimI"
                     /locus_tag="ACG930_001747"
     CDS             23071..23613
                     /gene="rimI"
                     /locus_tag="ACG930_001747"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFQ0518905.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23620..24084
                     /gene="rimI"
                     /locus_tag="ACG930_001748"
     CDS             23620..24084
                     /gene="rimI"
                     /locus_tag="ACG930_001748"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFQ0518906.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24081..25097
                     /gene="tsaD"
                     /locus_tag="ACG930_001749"
     CDS             24081..25097
                     /gene="tsaD"
                     /locus_tag="ACG930_001749"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFQ0518907.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
BASE COUNT         8327 a         4398 c         5377 g         7570 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggcaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagg atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc ctttttttga taaaaaaaat actagatgta
     4021 agataaaagt gtaaaaacga tttgttttag gacgggaaac gatgtgtacc gcaatcactt
     4081 atgcaacgaa agaccattat tttggaagga attttgatta tgagatgtct tataatgaag
     4141 tggtcactat tactccaaga aattatcgtt tcgattttag aaaggtaaaa aatttagata
     4201 aacattatgc aatgatagga atagcagctg gggtatccaa ctatccactc tattatgagg
     4261 ctacaaatga aaaagggttg agtatggcag gactgaattt tcctggcaat gctgattata
     4321 aagaattaca agaaggaaaa gataacgttg caccatttga gtttattcca tggatactag
     4381 ggcaatgctc aaccatagac gaagctaaag aattattggc tactatcaat ctagtcaata
     4441 tcgattttag tgaaaaacta cccttgtcac ctttacactg gttattagct gataaagaaa
     4501 aatcgatagt aattgaaagt atgaaagatg gacttcattt atatgataat cctgtcggtg
     4561 tgttgacaaa taatccgcca tttgattatc aattatttaa tctgaacaat tatcgctcgc
     4621 tatcaaatgg aacaccagaa aatcattttt caaaccagat cagcttgaat gtttatagtc
     4681 gtgggatggg aggattgggc ttacctggag atctctcttc tgtttctcga tttgtaaaag
     4741 ccacatttac taaaatgaat gctgcatcag gtgattcaga atctgaaagt atcagtcaat
     4801 tttttcatat actaggctca gtcgagcaac aaaaaggagt atgcgatact ggagaaagaa
     4861 aatacgaata tacgatttat tcttcttgct gtaacgttga taaagggatt tattattatc
     4921 gtacgtatga agacagtcaa attactgctg taaatatgaa taaagaagac ttggatcgtc
     4981 atgaattggt cagttatcca gtcataaaag agcaacagat aaactatgtc aattaattaa
     5041 tgaatagatc cgtttggtat catattttct gatacagtca taattagaca cgatctttag
     5101 gtcgtgtctt tttttgctgg tttttttgga aatagcatcc actaatattt ttttaacacg
     5161 aagagaataa ggtagcctca aaaaagaaaa catggtaaat tagatattgg gactttattt
     5221 tctgtaaaaa cagaaacttt catcttttgt tttcacgtga cgaaattgta agagagaaaa
     5281 tattcgtccg ctatttattc tatgataaga tgcatatgaa tgaaataaac agtaatttta
     5341 tattaggatg tgaaagttaa atgtgcggta ttgtaggttt tgttaacgac aaggacaaca
     5401 aaaaaacaat tattaataca atgatggatc gaatcgttca ccgtggacct aatagttcag
     5461 gagaatatat cgataaacat gttgctttag gattcagaag attaagtatt attgacttag
     5521 agggcggtac tcagcctatt tacaatgaag atcggacaaa gatcattatt tttaatggcg
     5581 aaatctataa ttaccagcct ttgagagaag aattgattgc agctggccac gtttttcaaa
     5641 cacatgcaga tacagaagtc cttttgcatg gttacgaaga atggggaaca gaattattgc
     5701 aaaagatccg cggaatgttt gcttttgcta tttgggataa tgaaaagaat gagttattcg
     5761 gtgcaagaga ccactttggg atcaaaccat attattatgc agaaatgaac ggaacattta
     5821 tgtttggttc agaaatcaaa agttttctgc ctcatcctga ttttaacaaa gaattgaaca
     5881 aagaagcgtt gaaaccttat atgactttcc aatattctcc attaaacggc gaaacattct
     5941 tcaaagatgt ctatcgtttg cctgaaggcc attattatac gtataaagat ggaaaaatag
     6001 acattcagca atattgggat gcagattttg aaacaaaaga aacgcattcc cgacaagaat
     6061 ggatcgaaaa aatcgacgaa accgttcaag cttctattga agcacatacg gtcagtgatg
     6121 tagaagttgg ttctttctta tccagcgggg ttgattccag ttatgtaacc tctgtattga
     6181 aaccagatca ttctttctca atcgggtttg atgataaaac ctataatgaa gcgattgaag
     6241 ccagaaaact aaccgaacta ttggacttag ataatacagc agcagtgatc gacggagaca
     6301 tgtcgttcaa agcattccct ttgatccagt atcacttaga tgaacctgat tcaaatcctt
     6361 cttgcgtacc tttgtacttt ttagcaaatc ttgcttcaca aagtgtgcgg gtagtccaat
     6421 ctggagaagg ggcggatgaa ctgtttgcgg gataccaaac gtatggattc catacgaatt
     6481 caaaattcat ccgtgtgatt gctcaaggat tgaaaaaatt accaaaagga acacgctata
     6541 atttaggacg taaaatcgga aaaatgaaaa atttccatgg acggatccat ttatatgaat
     6601 cacttgctcc tgcaaaagaa tattttatcg gtcatgctcg agtgttcgaa gaatcagaag
     6661 catcagaagt gttaacacca aaatatcaaa cagcaccatc tgtggatgaa atcatgactg
     6721 ttcattacga gaaaacagaa ggaatcaaag atgaagtcaa taagatgcaa tatgtcgatc
     6781 ttcatcaatg gatgccaaaa gatatcttgt taaaggcaga taaactttct atggcaagtt
     6841 ctttggaagt ccgagtacct ttattggata tcgaagtcat gaaattggct caacaaatac
     6901 caagtaagtt tttattgaat caaaacaaca caaaagatat tttcagacaa gctgcgaaca
     6961 aacatcttcc ggaagaatgg tcgaatcgtg tgaaattagg attccctgtg ccaatcaaag
     7021 cttggttgaa agaagaacac ggctacgaac aagtcaaagc attattcgaa gcagattttg
     7081 caaaagaatt ttttgatcaa gaaaaaatca tgaagttgct agatgaccat cacgaaggac
     7141 gtaaagaaga gcaaagaaaa atctggacaa tcttcagttt cttgacatgg tataaagtct
     7201 actttgtaga tgaaacgatt ccgcaagcag aagcaatcga ctatgtgact gtttgatgaa
     7261 aatcaaatat caataaaaaa gaggttttct cctaccgttt aacactgagt gataagaaac
     7321 aatttcaaaa aacagctctt cccgttttat agatattatg acttatggtt cggagttggc
     7381 agaggaacac cattgtttcg aacataaggg ggttgtgaca cgattttcgt cacaacccct
     7441 ttacatatgt tcaataatcg atttcttttt cttttgtccc atctttttta taaatgaaca
     7501 aagttgattc tttgttttgt gctacttgct ttcctttttc gattgcttct ttttttgtat
     7561 caaaatggtt gcttgccttt tttgcccctt tagatttcac gatccattgt tcttcctcat
     7621 attctacgat cacatctgaa tcaagcagtt ttccagcacg aggattcgta tcgtgttcat
     7681 ccgtcttgct tggatttttt tctttttcga aagttcgttt ttctgattca ctagcatctt
     7741 cataccattt ttttgcttga tcaatggcaa ttgggatcgc acggttatca gggtaccctt
     7801 catctaataa tgcatttgcg atgtcgattg ctttttttct tgtcaattta tctaagtttt
     7861 tcattgatgc aggaaagtcc ttcatgttcc atggcatatt agtatccccc tttattaaaa
     7921 aacataatct atataaacaa gtgtaagggt atttatacaa aaagaaaaag attttgtttg
     7981 agaagtaaaa ccgttgtatt tatcgtcaag tagttttact taacaaaatc gtgaaaaaca
     8041 ctagcaatct agaaaaaatc atggtaagat aatcaagtct gagagtcatc ttagaggatt
     8101 cttgtaaaaa tgggagggaa aaacatgcgc gtaaacatca ctttagagtg tacttcttgt
     8161 aaagaacgta actatctaac aagcaaaaac aaacgtaaca atcctgatcg tttggaaaaa
     8221 caaaaatatt gcccacgcga acgcaaagtt actttgcacc gtgaaacaaa ataatgtttt
     8281 taaagttctc aattccttgc tggtcaaaga attgagactt tttttatctc aaaacatcta
     8341 aaatcataag gagcggataa tatgtttatt tccatgtggg cacaagataa aaatggtctg
     8401 atcggcaaaa atggtttgtt accatggcga ttgccaaatg atatgcgttt ctttcgcgaa
     8461 cacacaatgg atcgaatttt agtgatggga agaaagacct atgaaggaat gggggatctt
     8521 tcacttcctt atcgccatat catcgtgttg acaacgcaac caaattttcg cacgaaagaa
     8581 aatgcggaag taatgcattc gatcgatgaa cttttgtcgt atagtcaaac gatctcagaa
     8641 gatatctatg tttcgggtgg tagtcggatt tttcaagaac ttcttcctta cactggtcgg
     8701 atctggcgaa cattgatcga tagcacgttt gaaggcgata cgtatattgg gaatattgat
     8761 ttttcagact tcgcccttat agaggagtat gaggggataa cggatcaaga aaatctatat
     8821 gcccatcgtt ttcaaaaatg ggaaagagta aaaaataggg ttgcttcaaa agaagaataa
     8881 aatctatgcg tctagtttgt taataagaaa aaaagcatct cacgactaat cgtgaagatg
     8941 ctttttttag ttaaaatcaa tttagttttt ctttgatatc attgaccatt tcctgactgg
     9001 caataggtcc gttatatagc caactagatt caggtccgaa ttgcagtaca tgattgtctg
     9061 tcactgcttt tagattcttc cagcttggtt cattgaacat ggcagcatct ttgtcactgt
     9121 tcacaaggat gatgtagtca gcatctaatt cagctagctt ttcagaggaa acagcagacc
     9181 agtcagaagt ggcttttttg gagacctctt ccactagatc aggaacacca aattccagat
     9241 cgtcgtatac gattcttcca cttgaccgat ttttgctgac cataaaggct gagttgttgg
     9301 tcacccacaa cactgcagct gtcttgttct cgattttatc tgctagttct tctcgagttt
     9361 tcttgatgga tttttgataa tcggaaatga ttttttctgc ctctttttct tttgccaaag
     9421 ctttgccgac atcttttagt tgttcttccc atgtgacatc tgttccgttt tttacaacat
     9481 aagttggcgc gattttgcta tattgttcgt atttcccgcc ttcgacagta gcggaagaag
     9541 aaatcaacag caaatcaggc tcaaagctta acactttctc ataaggaagg tcataagaaa
     9601 tcgttgggac atcctttaaa tcatcttgca gataatcttg aatggaacca ctgccaacag
     9661 tccactgggc gataggtttt tcccttagtg caatcagata gtcttctaag taactgccga
     9721 tgatccgttt gggcgcgttt ggaatctcta ctttatgtcc aagtgtatct gtgactgtat
     9781 gagtactatt ggatgaagtc gtcgaattgg cagttgtagc tgtttcttta tctgaagagg
     9841 gggagcaagc gctcagtact ccagccagca gcaatatgct agataatgtg aatacttttg
     9901 tttttaattt catttctttc ctcctaacat aattgagaat ctttctcatt ggttattatt
     9961 cctgatattt cgaacgctgt caaccgcttc atttggctat agatatgaaa gtagcgcttg
    10021 acgaaatgtt gaaacagcgt cataattgag aatgattttc agcgaaagga tgggtgaaat
    10081 gacgagatta agagcagctg acattgcagc cggctacgaa aacaaaaaaa tcattgaaaa
    10141 catgtctgtt acgattcctg aagggaaaat cactagtttg attgggccaa atggaagtgg
    10201 aaaatctact ttattgaaaa gttttacccg tatactacct gtgaaatcag gaaagatcat
    10261 tgtcaataac tctgatatct ctacatacag ttcaaaagaa cttgcaaaaa aaattgcatt
    10321 attagcacaa actagtgaac accctacagg tatgacagta gaagaagtag tatcttacgg
    10381 acgataccct tatcaaaaac tgttcagtgg catggacacg caagatcatg aagcaattga
    10441 gtgggcgttg gatgctacag gtctagctgg atttcgtatg cgggatatcg caacgctgtc
    10501 tggtggacaa acccagcgtg tctggatcgc tatggcgctt gctcaggaaa cagatatctt
    10561 gatcttggat gaaccgacaa catttttaga tccggcacac caattagaga tcctacagtt
    10621 attgactgaa atcaatcaaa tgaaacaaac aacgatcttg atgtcgattc atgacattaa
    10681 tcatgcttca cgtttttcag attatttatt agcaatgaaa aacggtaagt tgatcacaga
    10741 aggtacacct gaagaagtga tcacaaaaga gtgtatgaaa aaaatatttg agattgatgc
    10801 aacgattgtc acgcttccaa gaacaaataa accagttttt ctaacctatg atttgttgcc
    10861 aaaagagcag gaggatcaat tatgaggact atgaagaaaa atagactcct gcttttggtc
    10921 tgttttgttc ttttgattat tttttttgtt gctctttcaa atggcgcagc gactgtggga
    10981 aaagcagatt tttggcaggc gttgtttgat tttgatagat caaaacaaag tcaccaaatc
    11041 atacgaaata ttcgtttgcc tcgtgtggcg ggagcatttc ttgtagggag ttgttttgca
    11101 ttgagcggtg cattgatgca aggagtgaca agaaatcctt tagcagattc aggcttacta
    11161 ggaatcaacg cgggtgcttc gttggcaatg gcccttagtt ttgctttttg gcctaaagct
    11221 tctgattttt ctgtgtttct aatgtcattg gcaggttctt ttgctgtaac tttgctcgta
    11281 tttggttttt tgcagttttc gaaaatgggc atgaatcctt tacagctgat tttagctggc
    11341 gtagctatta gttctttttt tactgctatc agccaagcac ttacccaatt ctttaatctg
    11401 cagcaggatc ttgctttttg gtttgtaggc ggagctgcca atatcacatg gaaacaatta
    11461 gcagtattgt ttcctttata tatacttgct gttttggttt ctttttcatt aggaaaagca
    11521 atatctttga ttcatttgag tgaaacacat gcattagctc ttggaagtca tcctaaacga
    11581 acgcggttga ttgttttctg tctagttgca gtgttagcag ccattgccgt ttcgttagtc
    11641 ggacctgttt catttattgg gctgttggtt ccgccagttg ttcgcggaat ggttggaacg
    11701 gactatcgtt atgttctacc tgtctctttt ttagttggcg gtggattggt tatgttggcg
    11761 gattttacag cgaggatgat caatccccct tttgaaacac cttttggatt agtcattgca
    11821 ttgattggcg ttccgttttt actgatacaa gtaaggaggg aacaacggtg aaaaaaatat
    11881 attggacgtt ctatttcttg ctttttgtac ttgtcatcct gtctataggt agtttaatga
    11941 ttggtacgcc ttttatttac ctggatcagc tttttgccac gttcataggg aaagaatcat
    12001 cttctttggc gctgattgtt agagaatttc gagttcctcg attactgatc agtttattag
    12061 caggagcttg tcttggcgtt tctggttata tcttgcaagg agtaacaaga aatgaattgg
    12121 cagattctag tatattgggc attaatgccg gagcaggatt tttagtgatg ctttatttag
    12181 gtttcttttc gcactattcg ctgccgtttc tattgctagt tgtagccttt ctaggtggtg
    12241 ttttagctgc ttgctgtgtc tatcttgcgg cctatgatcg aaatggcttt ttgggtatga
    12301 atcgaatctt attgtccggt attgccgtta atgccggcct ttctgcatta acattgctat
    12361 gcacgattca attatctaag gaaaattatg gatttgtgaa tgcatggtta gcgggatcaa
    12421 tctggggtgc gagctggcct tatgtttggg cattgcttcc atgggcggtt atcttaattc
    12481 cgctaggagg actttatgca cagaggattg tattgctatc atttggtcaa gaacgcgcgc
    12541 aaggattagg ccttaacgtg gctaaaagtc aaaaaatcct tttgttgtta gctgttgctt
    12601 tggcaagcgg tagtgtagcg gtgacaggta gtttatcttt tgtaggacta ctagctcctc
    12661 atgctgcgaa gctagtcgta cgtaaagaaa ataactggac ctttgttctg agcggtttgt
    12721 tcggttccat ttttctgctt agtgcagata tggttgctag agtgattcta ctaagtgggg
    12781 aagtacctac aggaattttg attgcccttt ttggtgcgcc atattttctg tatgcacttt
    12841 ttatcagaca aaaacacgcg ctgaacagtt gaaattcatt aaaaaaggaa ggccaatcat
    12901 ttctaggtct tctttttatt ctatttatgc atttatttga aagttcgatt gctatttttc
    12961 tttttttcct ataccatttt atgagagaag gaagggtgag tttttggacc aattgaaagt
    13021 aagattacgc cggaaaggaa tcgaaaagct gaaaaatctg gccaaaagtg gcaagaaaaa
    13081 ggaaaaagaa cagcgaatct ataaacagct attcgccagc gagtactgga agtcagcaaa
    13141 agtgataggg acgactttat cgaatgaatt tgaactggat acacagccgg ttatccaacg
    13201 agcagaaaaa gaacaaaaga aaatagttgt acctaaaact ttgccgaaac gtcagatggc
    13261 gttttatgaa atggatgaac agtccgttct tgtacgttcg agttttggtg ttcttgagcc
    13321 acaatcagag aagctctatt tgccggagat gatcgatctc ctcattgtac caggtattat
    13381 ctacaataga gccggttatc gaatcggttt tggcggtggt tattacgacc ggtatttaaa
    13441 taattttcat aaaaaaacat gtagccttgt ttttcgtgaa caattgaatg aacaatggca
    13501 accggagagc tttgatcaga agatccaaca attgtttatt gactaaaatg aaatgggagg
    13561 ttttcatgaa ttatcaacag caaataaaat tgcgtgcatg gttaagacga ccgttatgga
    13621 cctatgcttt tttagggata cagacagcgg tcttcctcat gatggaatta tttccgcgac
    13681 ttgagatccc ttattatgcc ggaatgtatg gtccttatct tgttcacttc aatgaatggt
    13741 ggcgtttagt gacaccaatc ttcatccatt ttggactgat gcatttcgta atgaactcac
    13801 tgatactgta ttttatgggg cagcaaatcg aggcaatcta tggccattgg cgttttttct
    13861 tgatttatat gttcagcggg ataatgggaa atacagcaag ctttgctttt aacgaagcga
    13921 atgttctgtc tggtggtgca agtacttcga tattcggttt gttcggtgcg ttgtttatct
    13981 tagggtttca ttttaaacat aacccagcga tccagcagct agtcagacat tttcttttat
    14041 ttattgtgtt gacatttgtt tttggtcttc tggatacctc tgtagatgtt tggggacatg
    14101 tcggtgggct aattggcgga ttagtgttag ggaatgtttt gggtctaccg aaacaacaga
    14161 caagctattc gatacaccaa aggattcttt ctacactagt ttttgtattt ctttttgtaa
    14221 tatgtatttt actgggttta aaaaaatatg gtttacttgt ataatatgaa ggaagtgctt
    14281 aaagatggag agcttatatg atgtacagca gctgttcaaa aaatttggca tctttatcta
    14341 tgtgggtgca cgcatctatg acattgaatt aatgactatc gaattgcgta atctgtatga
    14401 tagccgtttg attgatcatg atacatacat gacagcgtgg cgcatattaa aaagagagca
    14461 ccgaattgaa gaaagccgaa agaaaggaaa tttgtaatgg acaagaagat tattgggatt
    14521 gatttaggtg gaacaacagc aaaatttgca attttaacac cagaaggaga gattcagcaa
    14581 aaatggagca tcgataccaa tattttggat gatggtaagc atatcgttcc tgaaatcatt
    14641 gaatcaatca atcatcgttt gaatttatat aatatgaaag ccgaagactt tatcggaatc
    14701 ggcatgggta ccccaggaag cgtggacagc gaagctggaa cggttattgg tgcgtataac
    14761 ttaaactgga cagaagttca atttgtgaaa aaactgatcg aggcaggaac aggaatcaaa
    14821 ttcgctatcg ataatgacgc gaatgttgct gctttaggtg aacgatggaa aggtgctgga
    14881 gaaaacgatc cagacgttgt attcgttact ctaggaacag gtgttggcgg aggtatcgtt
    14941 gctggcggaa atttgattca cggcgtgagc ggagctggag gagaaatcgg acatatcact
    15001 gtggatcctg aagggttcga atgtacttgc ggtaaacgcg gatgtttaga aactgtatct
    15061 agcgctacag gtgtggtacg cctaggtcgt ttcttggcag aagaatacgc aggggattca
    15121 aaactgaaag caatgctaga caacggagaa gaagtaacaa gtaaagatat ctttgaaatg
    15181 gctcaagaag acgatccgtt tgcattgatg gttgttgatc gcgtatgctt ctacttaggt
    15241 ttagcttgcg gaaacttggg gaatacatta aatccgtcaa gtatcgtgtt aggtggagga
    15301 gtatcggcag caggagaatt tttacgtagc cgtgtagaga aatattttaa agaatttact
    15361 ttcccgcaag taagagaatc aacaaaaatc aaattagcag agcttggtaa tgaagctggt
    15421 gtcattggtg ctgcctcatt agccttgaaa tttgcttaaa aaaacggagg cattacatgg
    15481 ttttatgggt aattaatatc attttgctat tgattgtgct tgcaatcatc ctttgggaag
    15541 tctatctacg agtaatggcc aaacgttcag caacgacttt gacagaagaa gaatttcgag
    15601 aaggaatgag aaaagcacaa gtaatcgatg ttcgcgaaaa agatgtgttt gatgctgggc
    15661 atattttagg tgcaagaaac atcccttaca ctgttttgaa agattcatta ggatctattc
    15721 gaaaagacca gcctgtctat atttacgatc aaaagaaaag tttgagcatc cgtacagcaa
    15781 ataaattacg taaagcaggt tatcaagaga tttatttact taagggtgga tatgacggat
    15841 ggtctggaaa aatcaaaagt aaaaaagtat aaaacagatg attgtatgac agctttaaaa
    15901 accgaatcaa tcattagatt ttgaccaaga tcacatgaac ggcgcaatgg atagttgtgc
    15961 cgttcatttt ttttattttg tgctattatc tacatatata agctaagcga aaaggtagaa
    16021 agaaggaaac aactatgatc aaattaaaac gtgtttacct tgatgctgaa aaagaggatg
    16081 gctatagaat actcgtggat agattctggc cacgaggaat ttcaaaagaa aaagcgcagt
    16141 tagatctgtg gttgaaagaa attgcaccta gtaatgaagc acgcaaaact tttgaccatg
    16201 taccagaacg atttgcttca tttgcaaaga aataccagca agaattgatt ttcgaagaag
    16261 aaaagaagca agctattttt aaactcagtc aacttatgaa agaacatcca gtcattactt
    16321 ttgtttatgg tgcaaaaaat gaacatcaga accatgctgt tttattgaaa aaatttatcg
    16381 aaatggaggc atgcaaatga aaatagggat cattggtgcc ggacctagag gattaagtgt
    16441 agcagaaagg attctccata ataatcagga cagacattct cttgaacttt ttcttttcga
    16501 tcccaatggt cctggaggtc gagtttggcg gttgaatcag ccaccggagt tattaatgaa
    16561 ttctgtttct caacaagtga cgctttttac agatgaaaca ttgtccagtg gaggattggt
    16621 aacacaggga cccaacttgt ttcaatggag taaaggacct gctacagatt atatcgaaca
    16681 gacggtaacc aaaaataagc aactaattat agaagaaatc aatcgtctgg aaaaagatca
    16741 gcaatctact cgatgtttat acggactcta tcaacgctgg tttttctcaa agttgcaaga
    16801 agaatttcca gcttctattc agtttgttta ttctttagta aaaaaagtaa gcaaaagaaa
    16861 agatggttat cttttacaga cagatcagca aagctattct atcgatcagc ttgttttagc
    16921 aagcggtcac tgggaaaatg atgagacaga agaagaaaga gtgtgggtag actacgcaaa
    16981 gaaaaatgtt ttactgtatc agcttccttc taatcctgca gatgtagatc tttcgaagat
    17041 accgcctaaa gaaaatgtct ttttaagagg tctaggctta agtttttttg attatgtcgg
    17101 attgtttaca gtatcaagag gagggcgctt cgagaacgaa aagggaaaac tggtctatca
    17161 tccatcaggc aaggaaccga ttgtatacag tggatcaaga agggggctcc cttattaccc
    17221 tcgaggaaga aatcaaaagc aaggcggagc aatggcatgg ccacggttac taacaaaaga
    17281 aaacctggag caatggcatc agtcgggatt tttgactggc gaaacatttt ttgactatct
    17341 gaaaaaagac gttgagttgt tttattacaa gaaaatcatc gaagaatatc acttgccgat
    17401 tccaaagaaa aattttgagc atgattttct ctccctctct tcagaggagt gtctcggaaa
    17461 gcatccagca ctaatccctt atagatggga ttggtcgtat ttagaaactc ctcttgccta
    17521 tcagaatgag cccttttcag aagctagccg aatatttatt gaagggcaga taaaagaagc
    17581 ggaaaaaggc aattgcacag gagcatttgc ttcaacattt gatgcattaa aagactggcg
    17641 tgatccaatc cggcaggcta ttgaatggca cgttttttct gctaaggaat acaaagaaat
    17701 actatgggga tggtttactc atctaaatag ctttttaacg atcggtccgc caatcattcg
    17761 gacgaaagaa ttagcagcac tgatagatgc gggtattttt catttgatcg aaccgccatt
    17821 tgatattcag caaaagcaca accgctatgt tatttctcta caagataaag aaatcagcag
    17881 tcgctatttg attgaagctc gattgccaca aacaagcttt tctcgttcaa gtaatcctgt
    17941 cataaaaaat ttgaaggaaa acaaacttgt tcgccctttt tcattttcag ataatacagg
    18001 aagttatcat tcagaagcta tagatgttga gcgaggtacg aatcgcgtga ttgatgcttc
    18061 aggggaaatc cagtctgact tttattgcta tggaatacct gttgaaggtg tggattggct
    18121 aactgcagca gtagctagac cttatacaga tccatggaat ctgagacagg cagataaaat
    18181 agcacaactt atattgactg acaaataaaa atacgcatga tgacttatct gttttttaga
    18241 aagtcttcat gcgtattttt aaataattat taacgagaaa cgcgtttacg cattgctttt
    18301 ttacggtttt cttcgatcat tgcttctttt tcgtcaattg gatcgatcac tgtttttttc
    18361 acagaagcaa ccaaaccagc aacggcagcg gctgttgcca gacttcctac taatattcca
    18421 gatacaaatt ttttcattga atccacctca tttattattt gttatatcta ttatggaaca
    18481 aaagagaaaa aaaggctagt tttacgtttg tttgtaaacc tttgcaaaaa atccttgaaa
    18541 atgtttacta aatgttttat tataaattta ccatatgaat ttacgaaatt ttactttgtt
    18601 tgttttcacc ataaaagtaa acttcgtttt ttaaattata tagaatcaac aaacacaatt
    18661 ttactaatca aaggagtgtt ttttatgaca attttagtac taggcggagc cggttatatc
    18721 ggttcgcacg ctgtagacca gctagttcaa aaggggtatc aagtagctgt ggtagataat
    18781 ttgctcacag gtcacaaaca agcagtacat ccagatgctc atttttatga aggagacatc
    18841 cgggataaag aatttctacg ttccgtattt gaaaaggaac cgattgaagg agtaatccat
    18901 tttgctgcaa gctctttagt aggagaatct gtcgaaaaac cattgatgta tttcaacaac
    18961 aacgtatacg gtatgcaaat cttacttgaa gtcatgcacg agttcaacgt gaataaaatc
    19021 gtattctctt ctactgcagc aacttatgga gagccgaaag agtctccaat cacagaagat
    19081 acaccagcta atcctaaaaa tccgtatggt gaaagtaaat tgatgatgga aaaaatgatg
    19141 aagtggtgtg accaagcata tggcatgcgc tatgtcgctt tgcgctactt caatgtagcc
    19201 ggagcaaaag cagatgcatc tatcggagaa gatcatacac cagaaacgca tcttgtccca
    19261 atcattttac aagtagctct tggtcaaaga aaagccttgg ctgtttatgg agacgattat
    19321 gatacaccag atggaacatg tatcagagat tatgttcaag tagaagattt gattgctgca
    19381 catattttag ctttggaata cttgaaagaa ggaaatgaaa gcaacttctt caatttaggc
    19441 agcagcaaag gatactcagt caaggaaatg ctagaagcag ctagagaagt gacaggaaaa
    19501 gaaattccag cagaaatagc accaagaaga gctggagatc ctagccgatt agtcgcttca
    19561 agtgaaaaag cgagagagat tctgggctgg aaacctgaat acacagatat caaagcgatt
    19621 atcaaaacag catgggattg gcatgtcagc catccaaatg gttatgaaga ataggggaat
    19681 gagatatgtc aatcagtcaa acgatttgtg attttgccac acttgcgatc gaagctggcg
    19741 gatggatgga aatggaccgc ttatatttac agaatcgtct tttagggatg gtaggagaag
    19801 atgctctaga aagcattgaa gtaagaccag ttaaggaaga atctgtagac ttattggatc
    19861 agcttgtcgc taaggcaaga gaaaatggtg ttctttcaga attgccagca gaacaagaga
    19921 tttttgaagc gcaattaatg gattttctca caccgccacc ttcagtcgtc aatgcattct
    19981 ttgcacagca ctattcgaaa agcccagagg aagcaactga gtatttcttt aatttaagta
    20041 agaaaaatga ctacatcaaa acaagagcca tcgcaaaaaa catcaaattt ccggcagagt
    20101 cggagtatgg tgaactggaa atcacaatca atttatctaa gccagaaaaa gatccaaaac
    20161 aaatcgcagc agaacgcgag gcggtaaaag tagactatcc tacctgcatg ctttgcatgg
    20221 aaaacgaagg atatagaggt cgcttgaact atccagcccg caccaatcac cggattattc
    20281 gaatgaatct agacggtgaa agctggggat tccaatattc cccttatgct tattacaatg
    20341 aacattcgat cattttatca gaacaacacc gcccgatgaa aatcacaaag gaaacatttg
    20401 ctagactgct tcggattact gaagtcttgc ctcattactt tgttggttcg aatgctgact
    20461 taccaattgt tggaggatcg attctttctc atgatcatta tcaggcagga cgtcatgaat
    20521 ttcctatggc aaaagcaccg atagaaaaac ttatcaaact agaagattat ccgcaagtca
    20581 tcgcaggagt cgtgaaatgg ccgatgtctg tgatccgttt gcaatcaaca gagaaaaact
    20641 tgcttattga agcagctaac tcagtattgg aaaaatggaa agcatattcg gatgaaacag
    20701 tatctatcag agctttttca gcagatggta caccacacca tacgattacg ccaattgcac
    20761 gaagaaggga caattacttt gagttggacc ttgtccttcg agacaacaat gtttcagaag
    20821 aacatcctga tgggattttt catccacata aagatgtcca acatatcaaa aaggagaaca
    20881 ttgggttgat cgaagtaatg gggcttgctg ttttaccacc tcgtttgaaa ccagaactag
    20941 tagaagtaga gcatttctta ttaggagaag aaaaccagat ggctgaatat catcgtccgt
    21001 gggcagaaca attaaaaaaa gaacatcctg atttgacgaa agatacggtc accgatgtcg
    21061 tacaaaaatc tgtaggtcag gtttttgcac gtgtactgga agacgctgga gtattcaagc
    21121 gagatgaaaa aggacaggca gcgtttgaac gatttactgc gattttataa acgtaaaaaa
    21181 ggaggagaga caaatggcaa caattaaaga cattgcgcag ttggcaggag tttctcctgc
    21241 tactgtttca agagttctca actatgatcc tgatctttcc gttggcttag ccacaaagca
    21301 aaaaattttt gaagcagcag aacgcttaaa ttatacgaaa catcgtaaaa atgcagcaaa
    21361 tactaagcaa acgcttcgcc tgatccagtg gtacgacgat acggaagagc ttgaagatct
    21421 ttattattta tctattcgcc taggaatcga aaaaaaggca gaagaagcaa acgttacttt
    21481 attgaaagaa acgtgggatt ccattagtga tcttccggca gatggaacga tcgcactagg
    21541 aaaattcgac gaagctcagt tattagaaat gaaaggatcc caaaatgcct tgcttttggt
    21601 agattctgac ggcacttctc aaggaatcga ctctctagtt gtcgacttta agtcaagtgt
    21661 tcaaaaagtc attgaacact ttgtctccca taaagcgcaa catatcgcta tgcttgctgg
    21721 aacagaatat acgaagaaaa accatcagcg gctaaaagat cccagaatta tggcatttca
    21781 acaagttttg gcagaaaaag gctacgacga aggtccaatt atcgaagcag atttttctgt
    21841 cgagtcagga tatcaagcag tgaagcagta tttaaaaacg aatccgcatg ttcctgatgc
    21901 gctttttgca gctaatgatg cattagcgat tggcgcactg aaagcgattc aagaaaaagg
    21961 tttagtggta ccagaagata tttctgtgat gggcttcaat gatgtcagtg tagcgaaata
    22021 tgtaacgccc tcgctttcta ctgtaaaagt ttataccgaa tggatgggag agctagcagt
    22081 ggagacgatt cttcaattaa gtaattccaa agcaccggtt tcaagaaaga ttattgtgga
    22141 aacagagttg attattcgag aatcaacgaa ataaaagatg gaaaagctgt gggaaaatgg
    22201 agtgataccg cagctttttt gtgtttcagg aaggggcaaa atttgcccgc cagcagataa
    22261 tcatgtatta ttgtactagt tttgcctttg gtattttcat cctcagaata aaaaagtatg
    22321 ctacaatgga aggcgagaat gtcatagcag aaaggatcaa atatatgatt acattaggaa
    22381 tagatactgc aaaccaaact ttggcgatcg gtgtggtaga agacgaacaa attcttggac
    22441 aaatacaaac aaatatcaaa cgcaaccaca gtgtaacact gatgcctgca atcgaccaat
    22501 tgtttgcaga tcttcaaata agtccaaaag acattgaccg aatcgcggtt tctgatggtc
    22561 ccggttctta tacagggctt cgtataggtg taacgacagc aaaaacgatt gcttatacat
    22621 tagataaaga gctagtagga gtatctagtc tgaaaaccat cgcggctaat tgcatcggtg
    22681 tggataatat tattgtgccc atgtttgatg ctcgaagaaa aaatgtatac gctggggcat
    22741 accgctggaa agaaaataga ttagaaactg tacttgaaga tgtacatatt tctgcttctg
    22801 atttgttcac acaactacaa aagctgaatg aagctattta tttcgtcggg agtgattgtc
    22861 acaaattctt ctctgaaata aaggaaatat tgcctagtgc gatgattaat acagttccag
    22921 catgggatat tccaagtggt gtaactgtgg ctcaattagg tgctttagtt gaaccagttg
    22981 cagagaaaca agcttttctt cctcgctatt taaaacgagt agaagcagaa gaaaaatggt
    23041 tggagacgca cacacctgga gacgaaagtt atgttgaaaa aatttagagc gtatgccaga
    23101 agcttttttc aagataaaat gatttataca gaaaaaacag tcgaacaaat cgatcgtcgt
    23161 tacgtactaa gagaattgac tacagaagat atcaaagagc tgctggatgt cgaacgagaa
    23221 gtctataatg gcgaattgcc atggacaaaa agtgccttta tatcagaatt gaagtcaccg
    23281 cttcctcatc tatatctagg tatctttgat aatggaagaa tgattggttt tatcggttca
    23341 agagcgttcg gtttagattg ccatatcacg aatattgccg ttcgaccggc atatcagcgt
    23401 aaacgaatcg gttcgctgct tattgacgaa atcgagaact ttgctataat gaatcgctgt
    23461 gagacgatgt cattagaagt gcgtatgagt aatcaagatg cacaaagact ttatcggaaa
    23521 ttggggtttc aagcaacaac gatcaaaaaa agatattaca ctgaaacaaa agaagatgcg
    23581 ttggatatga taaaactttt agaaaatgag tgagattagt tgatttgcag aaaaaaagat
    23641 tttgatgaag cgtacttggc agaatgcgta tggatgatta gcgaaaatgc ttatccacat
    23701 ggttcacctt ggacgaaaat gcagtttttg gcagacatcc aacagcctca ctctgattat
    23761 ctgcttttag ctgaagataa ccagatctgt ggctttattg gatactcgaa agtaatagat
    23821 gaagtcgaga tcacaaatat tgctgttgca gtttcagaac aaggaaaagg gcatgcacgg
    23881 catttgttac aattactgat tacggaacaa ataaaagatt cgctgcatgt ttttttagaa
    23941 gtacgtctat ctaatgaagc agcaagaaaa ctttatgaat cagaaaagtt tcgtatatta
    24001 ggtaaacgga aatcatatta tcgcaatccg acggaagatg cgatcattat gagcagaaag
    24061 ttaaaaacgg agacgatgaa atgaatgaag aattgattct ggcgattgaa tcaagttgtg
    24121 atgaaacgag tgtagcggtc gttagaaatg gaacagagat cttatctaac atcgttgctt
    24181 ctcaaataaa cagtcataaa cgttttggtg gcgtagtacc tgaagtagct agccgccatc
    24241 acgtagaaca aatcacctta tgcttggaag atgcactggt agaagctggt gtgtcggcag
    24301 aagatttatc ggcagtcgct gtcacttatg gaccaggact tgtcggctcg ttgctgattg
    24361 gtatttctgc agctaaggct tttgcttggg cacaccaatt gccgcttatt cctgtaaacc
    24421 atatggcagg gcatatctat gcagcccgtc tggttaaacc attccagttt ccattgatgg
    24481 cacttcttgt tagcggagga catacagaat tagtctatat gcaagaagat ggatcatatg
    24541 aaatcattgg ggagacaaga gatgacgcag caggagaagc ttatgacaaa gttggaagag
    24601 tattaggtct ttcttaccca agcggaaaag aaatcgatca gctagctcat cagggaaaag
    24661 ataattacca ttttccgcga gcgatgatcc atgaagataa ttatgatttc agttttagcg
    24721 gattaaaaag tgcatttatc aatttggtgc ataatgcaca acagcgtgga gaagatctag
    24781 acaaaaatga tttagcagct agctttcaag caagtgtgat cgatgtattg attactaaaa
    24841 cacttcgagc ttgtcaaaat tatccagtca agcaactgat tatagctgga ggtgtagcgg
    24901 ccaatcaagg gttgcgtgaa ggattgcagg atgctttggc aactaaactc cctgaggtag
    24961 aactagtgat tccccctctt cgactttgtg gagataatgc tgcaatgatt ggagcagcag
    25021 cacatgtgga aatgcaaaaa agaaattttg ctagctatca gttgaatgct gatccaagct
    25081 tggttttatc tgaataaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
    25141 cccaggaaaa acggcttctc atgtttttga cctggctgtt cttattaccg cgtatgcaag
    25201 cttttgaacg ccgtttaatc aagagttcgt aagcctgtcg tttaactctg attcacaagg
    25261 aacaatttca aaaaacagct cctcatgttt atgaacatta tgacttgtga ccgaagagtt
    25321 gacaggtaca caccgtttaa tcgaaatagg gctgtgacac gtttttgtca aagccctatt
    25381 ttttacatac ttttaatcat tattgttatt ttgctatttt ttacagctta tttatcatta
    25441 tccgttcctc tgattgccct cactgagtaa tcgtttattg tcgaggaata tcgaataatc
    25501 tagatcggat gaggacaaga cgcttcatct agttaatcta acagtatttt ttgcaaacag
    25561 tgaatattac ataactgaaa cacacataga aaatctttga gtcttgtcca gtgatctaaa
    25621 actgccggat ctttcagaag ttttagggag gaaaataagc agtgaccctg at
//
LOCUS       DAZKPE010000039        24347 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000039 DAZKPE010000000
VERSION     DAZKPE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.039"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..2059)
                     /gene="tkt"
                     /locus_tag="ACG930_001750"
     CDS             complement(62..2059)
                     /gene="tkt"
                     /locus_tag="ACG930_001750"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFQ0518908.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2161..2412)
                     /locus_tag="ACG930_001751"
     CDS             complement(2161..2412)
                     /locus_tag="ACG930_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFQ0518909.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2559..3182
                     /gene="lexA"
                     /locus_tag="ACG930_001752"
     CDS             2559..3182
                     /gene="lexA"
                     /locus_tag="ACG930_001752"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFQ0518910.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3361..3579
                     /locus_tag="ACG930_001753"
     CDS             3361..3579
                     /locus_tag="ACG930_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518911.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3867..4379)
                     /locus_tag="ACG930_001754"
     CDS             complement(3867..4379)
                     /locus_tag="ACG930_001754"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFQ0518912.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4393..6690)
                     /gene="recJ"
                     /locus_tag="ACG930_001755"
     CDS             complement(4393..6690)
                     /gene="recJ"
                     /locus_tag="ACG930_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFQ0518913.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6832..7275)
                     /locus_tag="ACG930_001756"
     CDS             complement(6832..7275)
                     /locus_tag="ACG930_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFQ0518914.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7276..8064)
                     /locus_tag="ACG930_001757"
     CDS             complement(7276..8064)
                     /locus_tag="ACG930_001757"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0518915.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8061..9002)
                     /gene="rnz"
                     /locus_tag="ACG930_001758"
     CDS             complement(8061..9002)
                     /gene="rnz"
                     /locus_tag="ACG930_001758"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFQ0518916.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9179..9766)
                     /locus_tag="ACG930_001759"
     CDS             complement(9179..9766)
                     /locus_tag="ACG930_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFQ0518917.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(9987..11300)
                     /gene="obgE"
                     /locus_tag="ACG930_001760"
     CDS             complement(9987..11300)
                     /gene="obgE"
                     /locus_tag="ACG930_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFQ0518918.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11588..12598
                     /gene="gap"
                     /locus_tag="ACG930_001761"
     CDS             11588..12598
                     /gene="gap"
                     /locus_tag="ACG930_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFQ0518919.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12683..13618)
                     /locus_tag="ACG930_001762"
     CDS             complement(12683..13618)
                     /locus_tag="ACG930_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0518920.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13804..14763
                     /locus_tag="ACG930_001763"
     CDS             13804..14763
                     /locus_tag="ACG930_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFQ0518921.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14849..15943)
                     /locus_tag="ACG930_001764"
     CDS             complement(14849..15943)
                     /locus_tag="ACG930_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFQ0518922.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16132..16893
                     /locus_tag="ACG930_001765"
     CDS             16132..16893
                     /locus_tag="ACG930_001765"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0518923.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17008..17448)
                     /gene="fabZ"
                     /locus_tag="ACG930_001766"
     CDS             complement(17008..17448)
                     /gene="fabZ"
                     /locus_tag="ACG930_001766"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFQ0518924.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17668..18423
                     /gene="fabI"
                     /locus_tag="ACG930_001767"
     CDS             17668..18423
                     /gene="fabI"
                     /locus_tag="ACG930_001767"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFQ0518925.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18533..19585)
                     /locus_tag="ACG930_001768"
     CDS             complement(18533..19585)
                     /locus_tag="ACG930_001768"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFQ0518926.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            19711..20631
                     /locus_tag="ACG930_001769"
     CDS             19711..20631
                     /locus_tag="ACG930_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFQ0518927.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(20911..21411)
                     /gene="cbpB"
                     /locus_tag="ACG930_001770"
     CDS             complement(20911..21411)
                     /gene="cbpB"
                     /locus_tag="ACG930_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFQ0518928.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21518..22036)
                     /locus_tag="ACG930_001771"
     CDS             complement(21518..22036)
                     /locus_tag="ACG930_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0518929.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22037..23392)
                     /gene="rph"
                     /locus_tag="ACG930_001772"
     CDS             complement(22037..23392)
                     /gene="rph"
                     /locus_tag="ACG930_001772"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFQ0518930.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23395..24216)
                     /gene="racE"
                     /locus_tag="ACG930_001773"
     CDS             complement(23395..24216)
                     /gene="racE"
                     /locus_tag="ACG930_001773"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFQ0518931.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
BASE COUNT         6930 a         5281 c         4291 g         7845 t
ORIGIN      
        1 aaagaacagc tgtctccaac ttgcagacag ctgttcttat cagtcaaaca attgcttgga
       61 tctatgatag ttgattgtac gtattcacga cattttctac tgtaaatcca aattcttcta
      121 aaattttagt gccaggggca gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg
      181 ttcctacgta gcgttcccaa ccaaatgatg cagcagcttc gatagccaca cgtttcttca
      241 ctgatttagg aagtacactt tctttatatt cagaagattg tttttcaaag aggtcaaagc
      301 ttggcataga aacaacagaa acatctttgc ctttttcagc caattctttt tgagctttca
      361 cagccaaatc aacttcagaa cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg
      421 atggagaaag aacatacgcg ccttttttca ccatttcatc tgctacttct tttgtagaag
      481 gcaatactgg aaggttttga cgactcaata caaggatagt aggcgcatct gttgtctcca
      541 tcgctacttt ccaagcagca cgtgtttcat ttccgtctgc cggacgaatc acttgaacac
      601 caggcatgca gcgaacagat gctagttgtt caatcggttc gtgcgttggt ccgtcttctc
      661 cgacagcaac cgagtcatgt gttaagacgt aaacaacagg agtatgttgg attgctgcta
      721 aacgaactgc tggtcttaga taatcgacaa agacaaagaa tgttccaccg tagatacgag
      781 ttccgccatg aagttggata ccattcatag ccgaagccat tgcaaattcg cggacaccga
      841 accagatgtt gcgtccttca taatgttcag gagtgaaatc tttatctgca gccaccattg
      901 tattattgga acctgacaag tccgctgaac caccccagaa gcttggtata gctttcgata
      961 attcttggat gacttcttta cttgaaacac ggcttgcttg actgcttcca acttcataag
     1021 ttggcaattc tgcatcccag ttttctggta gtttgccatc aaaagcatct tcaaattgtt
     1081 gtgctaattc aggataagct tttttataat tggcaaacat ttcattccat gcatcttcag
     1141 ctttttgtcc ttcttctatc atcgtttgat ggaagcgggc agctacttct tctggaacag
     1201 tgaaatctgg atactcccaa ccataaactt ctttagccat cttgatgcca tcttcaccaa
     1261 taggagcacc atgaacagca gatgttcctt ctttaggagc accatagccg atgactgttt
     1321 ttacttcgat caatgttggt ttgtctgttt cagcttttgc ttcttcaatc gctttagaga
     1381 ttgcttctag gtcatttccg tctttcacta agatatgttg ccagccatat gcttcatagc
     1441 gagcaccaac gttttctgtg aaagcttttg aagttggacc gtctagtgaa atatcgtttg
     1501 aatcgtataa aacgatcaat ttccctagtt tcatatgacc tgccatcgaa cttgcttctt
     1561 gagatacccc ttccatcaag tctccgtcac cgcatattgc atacgtatag tgatccatca
     1621 cattaaagtt ttctttgtta tacgttgctg caaggtgcgc ttctgccatt gccataccga
     1681 cagccattgc aatcccttgt cctaatggcc ctgtagtggc ttctacacca tctgtgtgat
     1741 gtacttcagg atgtcctggt gttttagaat cccattgacg gaattgtttc aaatcatcga
     1801 ttgtcacttg atagccagct aaatgaagca agctatacaa cattgctgac ccatgtcctg
     1861 ccgaaagaac gaaacggtcg cggtcagccc agttttttga tgtcgttgga tttactttca
     1921 ggtgttttgt ccataacgca tatgccatag gtgctgcgcc catcggcaat ccaggatgtc
     1981 ctgagtttgc tttttggact gcttcaatac ttaatgtacg aattgtgtta acgccaagtt
     2041 ggtcaatttt gtcaaacaaa ataacccctc ctattaattt aggttttttt tacctttatt
     2101 tcttacactt tcattctata agatgtcaca cgaaaaagca atctttttca gtatttttta
     2161 ctaaaagttg tcatttcggt tgtgtaagcc ttttttcttt tggatttctt ttaatttttc
     2221 cggggtcacg tcattgccct caggatcgac gactttcatt ccttcgatat gatgacgcat
     2281 accggaacga aaagcttcca aatactcttt gcgtaagttg atttgttctt gttcttcggc
     2341 ttttgagaga ccattttcct tctttttacg tgcaagttca ttgatcctct ctattttttc
     2401 aggtgacagc atgctcagcc ctccttttac tctccttcat attatataaa aactgaaaaa
     2461 aaaacaacta gataaactaa ataaaatacg aacattcgtt tgatttagcg ctttttatat
     2521 ggtactattt atttatcaag tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa
     2581 gacaaatcga agtcttacga tatatccatg aacaagtaac ccaaaaagga tacccgccga
     2641 ctgtccgtga aatcggggaa gctgttcagc tttcttctac ttctactgtt cacggtcatc
     2701 ttgcacggct tgaaaaaaaa gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg
     2761 agttgacaaa acaaggttta gaaaagattg ggattcgtcc aacaactatt ccagtacttg
     2821 gcgtcgtaac agctggagaa cccattttag cagtagagga tgcttcagac ttctttccaa
     2881 tccctcctaa tctttcttcc gaagaaggca gtctctttat gctgacaatt cgtggagata
     2941 gtatgatcaa tgctgggatc ttggatggtg acaacgtgat cgttcggaag caagaaactg
     3001 ctcaaaatgg cgatattgtc attgcaatga ctgccgagga cgaagcgact tgcaaacgat
     3061 tctataaaga aaaaaacttt ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca
     3121 tcttagatca agtatctata ttaggacgag tagtaggact ttatcgtagt catatctatt
     3181 aattgctact aataaaagaa aactttttaa aaagagtttg agacgatggt ctcaaactct
     3241 tttttcgccc gggttcttct tctttcaaat ttttatcact tccctcttta caaaccgaac
     3301 aaatattcgt atactaaata tacgaacaat tgttcgcata aattaacgag gtgagaattc
     3361 atgaaatcaa tgagacgtct tggcttagta ttaactgttt tgtttttagg tattattatt
     3421 ggtaatttcg gcatacgtcc agctttactt gtgtttgttc cgttatttac tttgtggttc
     3481 atgttgtggg atgaaaagaa gtaccgtcaa tctgagcggc gcagaattca tgaagatcat
     3541 ttctatcatg agccctacta cagatccagg caatcataat aaggattgac tgctaattat
     3601 tcaaaagaca agaagttaaa cttttacggg ggtgtgacaa aaatcggtca catccttttt
     3661 tcgaataaac ggtgttctaa agccagtttt tcggtattaa gtcaaattgc ggaaaaagtg
     3721 attttttaaa cttctactgg tctttgcttg tttccattta taaaaaaata gcgaccctca
     3781 aaagtcagat agagaatctg acttttgagg gtcgctttaa aatcgcttct ttaagaataa
     3841 catcaagaat agcttctttt ttctgcttaa tattccatta atgtaatgat gtcatatcct
     3901 ttgattttgt cgcgtccatg gagatccatc aattcgatca aaaatgcgca gcctacgact
     3961 acaccgccta attgttcgat cagttcgatc gtcgctttga ttgttcctcc agtagctagc
     4021 aaatcgtcac aaatcagcac acgttgacct ggtttaatgg catccttatg caatgtcaat
     4081 gtatctgttc catattctaa tccataagtc acttcgatgg tttctcgagg taacttccct
     4141 tttttgcgga ctggggcaaa accgactcct aactcataag caacaggaca tcctacgatg
     4201 aatccacggg cttctggccc aactaccata tcaattcgtt tttcttttgc ataatttacg
     4261 atttgcttcg tagcttcccg ataagcgtca ccatctgcca tcagtgggga aatatctcga
     4321 aacacaattc cttttgacgg atagtcggga atactggcaa tataatcttt taaatccact
     4381 ctttgtttcc tcctaggttg ttaaccattt ctttatggta ggaatatcgc tcaaaagcaa
     4441 aaattcctca actttgattt tattgagccg ccgctggtat aatctgctct cagtcaaagg
     4501 atgactttct gggctagcga ctttttgtaa aacaccgttc tctattgtaa caaatttcaa
     4561 ttcaaaaaac acctgtatca taaaaattaa taatttttca gggatacgca aatattgagc
     4621 tattgctttt attttatgac gtatatcaat tcgttcttga gaatggatca gtttaaacaa
     4681 ttttgcgtac tgttctcttg tgcctacccc attcaaatag gcctcatcag gcgaaatccc
     4741 catcagataa acacgattga atgaataaga ccgaaaaact tctttcagat ccgctaaatc
     4801 atctggacaa tccataataa ctagagagtt cggttttctt ttttcaatta ttgcctttac
     4861 agaatctagt ccttcgaaaa caatcgcagc ttcctggata atctcaggca cgaatttcaa
     4921 cgtagaagaa tcaaatgcta aataaaggct accttccgac gttcggctct gttcacggaa
     4981 acgttttgcc cgccaatcaa atacttgcag accacccaca gaaaaatcag ataccatcag
     5041 ctgcggtttc ttacgcccgt tccattcatt gatcgaaagc tttcctacca catctacctg
     5101 attattcagc agttcttctt cttgagtacc aaaaccaaaa gcgaccgcat caagctgact
     5161 cgatgcattg gaaaggacaa atttcagatg ctgttggttt gctccgattc ttttgatatt
     5221 ttctgcttgg acttgtcgaa ataaaaactg aggcaaagga ttatccgtac caaatggcgc
     5281 caatagtttc agctcatcaa ttcgctctac tgttacttca tttggcagca atacttcatc
     5341 aattctcaac tcaggccctc tcatcaagtc aatttgatga tcgactatat attggttcat
     5401 cttctcctgt agtatagtga cattttcact tggcatcgtt aaaccgactg ctgcatgatg
     5461 tcctccgaag taagtaaata aatctcgcat ctggtcaagc atttcaaaaa gattcaaggc
     5521 ttcaatacta cgtccagatc ctttagctga tccatcttct tttaaagtaa ggacaagcgt
     5581 tggtttaccc gtttcattca ttattttccc agcaacaatg cccaaaacgc cttcatgcca
     5641 tcctcggttt accaatagat ggatatgatt ctccttattg accatcgcta atgcttcttg
     5701 tgttatctgc tctacgattg cttttctttc ttcattgatc tcattcaatt tttttgcttg
     5761 aacggatgct tcctcttcat caaacgtcgc aagtaacgag acggcaggac gtggatcgcc
     5821 catccgaccg attgcattta gtctgggagc aatcgaaaaa ccgatcgttg tttcgtctgc
     5881 gtccctcatt tttacgccgc tttcttcaaa tagcgcctga agtcctatcc gttctgaatg
     5941 atgaatggca ttgattccta atgaaacaag gattcgattc tcatcagtca atgaaactaa
     6001 atcggcgatc gttcctatcg ctactaaatc caaaaattct acaggcggtt cttccaataa
     6061 tgcagaagct actttgaatg ctactccgac tcctgccaaa tctggaaatg gatagtgccc
     6121 cgctggatga cgagggtgaa caatcgcata agcgtctggt aaattctcag gtagttcgtg
     6181 atgatctgta atgatcacgt ctacaccagc ttgctgagcg tatgctaccg catcatttcc
     6241 tgctaccccg ttatcaacag tgatgatcaa ctggattcct tcttcgatct tttcttggta
     6301 tacagattgg tttggtccat acccatgctc aaatcgattt ggcaggaata cttctacttc
     6361 tgcaccaagt aattccagtg tttctttcat taccgttgca ctggtgatcc catctgcgtc
     6421 ataatcaccg taaacgagga ttttttctcc actgattaca gcttcttgga ttcggctgat
     6481 tgctttatcc atatcgtgca tcagatacgg atcatgtaat tcttgttcct ttggatgtaa
     6541 aaatcggttg atatcctttt cctcatggta acctctttgc cacagtaact taccgacaaa
     6601 tggagataat ttcagttcac ggatcatttg gagaaaggat tcagaaggct ctgtctcgct
     6661 taacttccaa tcaaaatttg cttgtctcac tttctcactc ctaacttagt tattatagca
     6721 aaggaaatca gcaaaaaaaa gcagaaagaa agaataaaaa cagatcagat ccgctagaca
     6781 gatgttcagc aggacctgat cttttgtacg accatttatg aaatatccct attagtcaaa
     6841 ataattgaag ctttgtttgg gcgattgagt tttttgttct tccggcgctt tcaattgact
     6901 gatttgtgcg gttttcgctt gtaactccgc ctgataagca gcttccaact ccgcacgttc
     6961 gtttctaaac tcgcgttgct gttcttcttt tgcttcttca attttctttt gaagttctgt
     7021 ttgatattct gacatttcct gagtcagctg tttgatttgc tttttttgct gccatagtgt
     7081 tgccgaagca gtcaaaaata caatcagtgc accaatcagc gcagaaccga tgatcactaa
     7141 gatcaatggc gcagaaaagg aagtgaagcc aaaacttaca ggaacatttt tattgttcaa
     7201 tacagcaaaa agaacaataa tcaaaactaa aacaaatcca agaatcacat tgctttgctt
     7261 tttcaattcc ttcacctact ttttgttaaa aattccgctg gctaaataat caccaatcgt
     7321 tggaaacagc gtataaaatt ttgatgcaac ttctaaaata aacggttgat tgatttcccg
     7381 ttttggatgt ctcatattgc ggacgatcat ttttgccaac ttggcaggtt ctaaaacgat
     7441 ttgtccgact ttttccaaat agcttccgct tggatcagcc ttatcgaaga aatctgtctc
     7501 gattggacct ggattcactg tcgtaacagc tacgccaagt ggtttcaatt ctaatcgcaa
     7561 agcgttggag aagccaagga ctgcaaattt cgtggcagaa taaaccgttg attttgcagt
     7621 tgccattttt ccagccatag acgcgatatt aatgatatga ccttgtcttc tttctgccat
     7681 atcgatcgca aatttttgtg tcaaaaccat cattcctaag atgttgactt caaacatatc
     7741 gtatgctttt ccaaggtcga atgtaaggaa gtcttcgaaa atcccaaaac ccgcattgtt
     7801 taccagaata tcgacgcgcc cgacttcttc catcaccttt tcatataatt cgtccacgct
     7861 ttcaggattg ctgacgtcta ccttgaaagc ataagcctct ttgccgctca agcgtctgca
     7921 ctcgtctctg acaccttcta caaatgccat tcttcgtgcg caacttataa cgattgctcc
     7981 ttgctttgct gcttcataac agatttgtgc gcccagaccg cctgaactac ctgttactaa
     8041 aacaacttta tcttctaaat tcatgcctct tcctcctcgc gaaatggaat ctcaatgcta
     8101 tcaaaatctt tcatgatcgt cgtgttttca aacacttctt gtgcttcttt ttcaagctct
     8161 aaagctgctt ttcctaaata tctcgcactg atatgagtaa gtagcagccg ttttgcctgc
     8221 gcttcttttg caacttcagc agcttgatga gtcgtggaat ggaaatagtt gtgcgccatt
     8281 cttgcttcat ctttattaaa tgtgctttca tgtaccagaa tatcgctatt ttccgcaagc
     8341 acaacggaat tatgtgtttt tctcgtatcg cctaaaatag tcacgattcg tcctttttta
     8401 tctggaccta cgaaatcttt tccattgatc gtccgcccat cttctagttg gatcgtttca
     8461 ccttgcttca gtttgccgta cagtggtcca gctggaatac ctaattcttt tagacgatcc
     8521 acctgcaatt ctcctttatg atcatgttca accacacgat aaccaaaact gtcgatccca
     8581 tgatttagtt tttttgtata aacagaaaat tgctgatcag taaaaatcgg ggctgtttca
     8641 tttagctcaa tgaatttcag cggataactt aaacgcgttt gcgaaatacc taaagagact
     8701 tttatgtatt cctctatccc ttttggcccg taaatctcta atggcgtatc cccaccttga
     8761 aatgaccggc tgctgatgag cccgggaagt ccaaaaatat gatcgccgtg taaatgtgta
     8821 ataaaaattt taccgatttt tctcggacga atagtcgttc gcaaaatctg catttgcgtg
     8881 ccttcgccac agtcgaacaa ccaaacttca ttgcgctcgt ctaaaagttt caatgctata
     8941 cttgtcacat ttctatgttt tgcaggaaca cctgcacctg ttcctaaaaa ttgtaattcc
     9001 ataatctacc tgactttctt taagttcctc tttaatttta gggtaaaaag aagggataat
     9061 caaccgtaag tcgagaatgg gttcaaatta aaaataacgt tctaaagcga tagcgttttc
     9121 tttgaaaatt actataaaaa cagcagcgaa cccgtttgag atcctctgct gttttttatt
     9181 aatttgaaga tccagaactt tcattgtcgt tggaagtttg cggatgtttg tccttccaag
     9241 tcttttgtgc agcttctttc gcatgatttt cagcttcttt cgcatcatgc acatcttttt
     9301 cgacatcttc ataatccaag cgggtaattt ctccgcctaa ttccatcatt accaattgat
     9361 tcagtgggcg attgtcctct tcatcagcaa tcaagatcag tcctgtagct ccttcaccga
     9421 ttttatttcc tacaaagtcg aacacggtct gggcatcttt tatttctttg gcatcttgtg
     9481 tcgcaccgat cattcctccg gcaaaccatc ctaataaaat ccctagcgga ccacctaata
     9541 caccaaccaa cattccgatt aatccacccg tagaagattt gttattaccg gtaaagtcga
     9601 taaaatcttc tattttgaat tgatgtgtcc cattaggatc atggctgaca actgccatct
     9661 gttctccttt aatcgaacga acagcatgta actttttgat ttctgaaaat gcctgatatg
     9721 cctggctttc tacttgaaaa tttaaaatga ttactcgttt gctcattaaa aacgcccctt
     9781 tcataccttc ttgttattta ttttaccttt aattgtaaaa taagaaaaga aaagcactct
     9841 ttttttccaa taaaataggg ctgtgacaaa agtcgtatca cagctccttt ttccgaataa
     9901 acggcgttct tgaagctgat cacttctgtc acaacctccc ttaaatctga atctatattt
     9961 tttggtattt gtttttattt gcttgcctat tcgacaaatt caaattcaaa ctcaccgata
    10021 cgtacaaggt cgccatcttt cgcaccgcgt gcccgaagag cttcatccac acccatacca
    10081 cgtaattgac gagcaaaacg catcactgtt tcatcatgat cgaaattcgt catttggaat
    10141 aatttttcga tcttctcacc agataagatc cacgttgcat ctgaatcacg atcgatttgg
    10201 aactcaggac cttctggatt gaatccatag tgtacagttt cttcttccag ttcttcttcg
    10261 tacaatggga attctggcgt tacttctaac aaatctgctg tagcattcaa taacgcgtcc
    10321 aatccttgtc gagtcactcc agaaattgga aatactggga tgtcatcagc aaattcatct
    10381 tctttttcct tgttcagctg ttctttgaat ttcactagat tttccggtgc atccggcata
    10441 tccattttgt ttgccacgat gatttgcgga cgctctagca agcgtaagtt ataagtagat
    10501 aattctttgt tgatggcaag atagtcttca taaggatctc gtccttccat cccactcata
    10561 tcgatcacat gtaaaattac tcgtgttctt tcgatatgac gaaggaattg tgtacccagc
    10621 ccaacacctt gcgaagctcc ttcaatcaag cctggcaagt ctgctgcggc aaaacttctg
    10681 ccatcacttg tagtaaccat tcctagatta gggacgagcg tcgtgaaatg ataagcgccg
    10741 atttttggac gagcagatga aataacggat agtaaagtcg atttcccgac agatggaaaa
    10801 cctacaagtc caacgtctgc caatactttc aattctagtt cgatttttcg ctcttgtcct
    10861 ggttcgccgt tttcagcaat ttccggtgca ggattccgag gagaggcaaa acggatattc
    10921 cctcgtccac cgcgtccacc ttttgccaca actagtgttt gaccattttc aattaaatct
    10981 cctaaaagag caccagtctc cgcatctcgg acagtggttc cttgtggtac tttaacatag
    11041 gtatcttctg aaccacgacc gtgcatccct ttactcatcc cattttcacc tggctgcgct
    11101 ttgaaatggc gattgaaccg aaaatccatc aatgtacgta acccttcatc gacgatcaag
    11161 atgacatcgc cgccacgacc accgtctccg ccagccggtc cgccgtcagg aacgtatttt
    11221 tcgcgacgaa atgcaaccat tccgtctccg cccttgccag ctttcacatc gatcgttact
    11281 tgatctaaaa acatggacat aattaagtcc tcctattatt catttattta tttgactgcc
    11341 tgaatttcca caataaacaa aagtcttact tattttatcg gtgaaatctg attttgtcta
    11401 tcatttcagc aaaaagattg tttaccttct tcttttttta tcatttggta aggtttccaa
    11461 ccttttttct gctaccaagt ataatttttt gacaaaatat tctttgcgta gcagaataac
    11521 agtgtattaa ttgtattaat tgaggatgcc gtttcacagc acccctaata aaggaggaac
    11581 ttttgatatg acagtaaaag taggtattaa cggatttggg cgtattggcc gtctggcttt
    11641 ccgccgcatc aaagaagtct cagatgatat tgaagtagta gcaatcaacg acttaacaag
    11701 tccaactatg ttagcacaat tattgcaatt tgactctact catggtactt atcctggcac
    11761 agttactgca acagaagact caatcgtagt ggatggcgaa gcaactcgtg tttatgcaga
    11821 acccgacgca agcaaaatcc cttgggcaaa agaaaacggt gtagatatcg tactagaatg
    11881 tactggtttt tatacatctg aagaaaaagc aaaagcgcat ttagatgctg gtgtcaaacg
    11941 agtagttatt tctgccccag ctggtgctat gaaaaccatc gtctataacg tcaatgatga
    12001 tacattagat gaaaacgaca aaatcatctc agcaggttca tgtacaacaa actgtttagc
    12061 acctatggct tatttcttaa ataatgaatt tgggatcgaa gttggtacaa tgacaacagt
    12121 tcatgcctac acttccacac aaatgctctt agatggacct gtaaaaggcg gtaatttgcg
    12181 tgctgctcgt tcagctgctg acaatactat cccacattct actggtgctg cgaaagcaat
    12241 cggcttagtt atccctgagc tacaaggaaa attacaagga cacgcacaac gtgttccagt
    12301 cgttgatggt tcattaactg aattggtttc agtattgaaa acaaaagtaa ctgctgatca
    12361 agtaaacgaa gcaatcaaaa aacacacagt tgacaatcct tcattcgggt atgatgaccg
    12421 tcaaatcgtt tctagcgatg tcattggaac aactcaaggt tcgatctttg acccaacgca
    12481 aacagaagta acaactgctg gtgatttcca acttgttaaa actgttgcat ggtatgacaa
    12541 tgagtatgga tttacttgcc aaatgattcg cttactagaa aaattcgcta acttgtaatt
    12601 tgatagatca atcgataaaa gaagcctttg actggatcca gtcaaaggct tctttctttt
    12661 catcccctac ttttaaactc gttcaatgaa catattggct taaaaattgt tggactactt
    12721 gctgatattt ttcaggatct gtcttgtatg cttccgcatg ctcggctcct tttacaacat
    12781 acttttcttt tggtcccttc gttgcacgat agaccttatc taacatttca aatggtacaa
    12841 atgtatcttc gtctccatgt ataaagagca ttgggcgctg gtttttcttc aattgttcca
    12901 ctgcatttgc ttcaccgaaa aagtagccag cacggacttt tgtcactaga ctcgttactt
    12961 gcataagcgg aaatgctgga agactaaaca tatcgtctag ctgataagca agctcatcat
    13021 gaacggaaga ataaccgcaa tcttcaatga ttgctttcac attatctggt agtttttctc
    13081 cgctagtcat cataactgtt gctgctccca tgctgacacc gtatagaacg atttcttgcg
    13141 attttccatt gttttctagc actttgttta tccactgtac atagtcttta cgctctggcc
    13201 atccaaatcc aatgtaatcc ccttcgcttt ttccatgtcc tcttgcatca ggaacaagga
    13261 cattgtaacc catatcatga aacatctttg cgtaattggt catcgtttca gcgtttccca
    13321 tatagccatg agccacaaga gctgtttttt cacttttcgt ttcagcagga agataaatcg
    13381 ctgataattt cagaccgtct tttgaagtga tggtccaatc gcttcggttt tcttttgaac
    13441 taaaccattt atgtgcatcc gtttctttgg atgtctgtgt tgtaccaggt gtatcttcgt
    13501 ctaaaaagtc tttctcagaa ggcacaacag cataattata aaaataattc cctgcaaaca
    13561 ctaacgcaac aatcagagct aaagcgacgc ctaaaaggat tttcatccaa agtttcataa
    13621 atcatccatc tcatttctct tttttcatat aaccttgaat tagtataatc aaagaatctc
    13681 tactatgcaa tgttcatttt tataacccgc gaattgtaaa attaagttag aaaaataaaa
    13741 aggcatttat ggtacactca aattgtattt ccgacgaaag aaaacaaagg agtgtaacca
    13801 taaatgacct acaaacatct taccatagac gaactgacaa tgatagaatc atattatctt
    13861 caacataata agccggttga aatcgctaac cgaatgggac gtgctataca aactatttat
    13921 aatgtagtca ataagttcaa gcaaggcaag actgctcttg attattggca ccagtataaa
    13981 gaaaataaga aaaaatgtgg tagaaaagtc attcaattac ctgctcatga agtagattac
    14041 attaaagaga aagtcactct tggttggacg cctgacgtca ttatcgggcg aaaagaaagg
    14101 tctgtttcat gcggtatgag aacactttat cgtttatttt ctaaaggaat atttgatatt
    14161 gacacactac cgatgaaagg taaaagaaaa cccaatggcc atcaggaaaa acggggaaaa
    14221 caacagtatc agcgctcaat ccatgatcga cctgataatt atcctgattt caattctgag
    14281 tttggtcacc ttgaaggtga tacgatcgtt ggcattcatc ataaaagtgc cgtcattact
    14341 ttagttgaaa gattatctaa agtcattatc acgattaaac ccaacggccg taaggcatta
    14401 gatattgaaa ctgcccttaa tcaatggttt tctcgcttcc ctaaaaactt ctttaaatct
    14461 attacgtttg actgtggaaa agaattttct aactggaaag ccattagtaa ccaacatgat
    14521 attgatatat attttgcgga ccctggaaca ccttctcaac gcccattaaa cgagaattct
    14581 aacgggattc tgcgtcgtaa tggactgccg aaatcaatgg attttagaaa agtgaatcag
    14641 acatttattt ccagtgtcag caatcaacgt aatcatattc caagaaaatc attgaattac
    14701 agaacaccaa tcgaaatatt tttgagctat gtacaagaag cattttattc tagcttaatt
    14761 tgacaaatca taacctataa aaaaacaaaa taaaaaagca gaaataactg gctatttcta
    14821 gcggattatt tctgcaataa ctaattatct attttttatt ttcaattaat ttaaagcttg
    14881 accatggttt caaaaagtca aggaggaata attcgtcatc ggagattctt cctacaacat
    14941 tgacacgtcc gtcgtttttc atatccttca aggcgatttg tgtttctcct ttgtattgac
    15001 cgtacccttc attgtcaatc agtacatccc catgatgcat atctcgcgta ttatgaggcg
    15061 ggaaatcttt atctttgtag tatacacgag tcatcgttga acgaaggata tattctgagc
    15121 gatcccctcg ataactatga aggttatcaa acaagcagat tcgttcgttt tctgtaatac
    15181 cttcttccgt atctactttc aatgttggat aatccgcgtt aaatgcttct gccatttctt
    15241 tcaattcttc ttcacttgcg tacgcatttc caatagaaat atcatcaatc aatcctgtaa
    15301 ggattaaatg cttcacttgt gtcgcaattt caagatctcg gtggtcttcc agcgtgcaca
    15361 agccatcttg cgtaggccaa gggccaaact cagcagattg cgaattgacg aatgccatcg
    15421 tattcaaatt atattttctg aatttttctg aacaaaaaac aaagtgttcg tatcctaaac
    15481 cagagtatcg atgaggataa aaattatgag aacctaataa attatccgtg tttggcgaat
    15541 aactcatgat gttgtcaacg taattcgtgc ccgaactcat attgatctcg attttgatac
    15601 caaaaggatt gcgcgtcatt tttgcttctt ctgctcctgt gaatccgata tctaagcgga
    15661 ccccgtaggc acccatctta tggaaaaaag ataagtcatc gtaagaaatc tccaactgtt
    15721 caaataacgc tggattgata tcaaccatta cttccatgcc taggctattc gcgtaatcaa
    15781 ctacttcttt aaattctgaa agaacttttt ctttatcatc attgatctgc agcaaactgg
    15841 taaaaacccg tttataccca tacttatgag ctaaatccaa gtacgctttg tccttttcaa
    15901 atgttgaccg ttctggataa atcgagattc ctaattttcc catattacca tttcctcctg
    15961 catcttttcg tttttgtatc cacttacatt atagcaaaca caaagtaaat ggtctacacc
    16021 ttttcttttt cttttaaaat aaatgataaa ttccaataat ttaagtaggt attttccctc
    16081 tattttgtta tcattaaaga taacaaaata gtaaattgga aaggaacagt tatgaagaaa
    16141 aataaagtta ttttaagtat tagtttagca gcagcattgc tgtttgctgc tggttgttct
    16201 gcaaacaaca cgacttcttc tagttcgtct acagaaagtt caaaaagtac atctactgcg
    16261 gaaagcacga ctgccagtag cgtcgatttg aacgcattgg aattaccaca attgacgaaa
    16321 gatgtcgccg aaaatgaaga tctggtcgaa atggtgacga ataaaggcac aatcaaaatc
    16381 aaattatttc ccgaacacgc accaaaagcg gttgaaaact ttatgacaca tgcaaaagac
    16441 ggttactaca acggactgac tttccatcgc gtcatcaaag atttcatgat ccaaggtggc
    16501 gatcctaaag gcgatggcac tggaggggaa agcatttggg gagaaggatt tgaaacagag
    16561 atcaacaacc acctttataa tataagaggt gcgttatcta tggctcgctc acaagatcct
    16621 aacagtaacg gcagccagtt ctttatcgtt caaaatacag atgatatgca tgatggtctt
    16681 ttaaaagacg actatcctca agcaatcatc gacgcttata aaaacggcgg ttatccttca
    16741 ctagatggcc attatactgt cttcggccaa gtgattgaag gaatggatgt cgtggatgct
    16801 attgcaaata tcgaaacaga tagttcagac aaaccaaaag aagaagtaaa aatcgataaa
    16861 atcaatatac tgcaagaagc aaaacaaaaa taaaaaaata acgtctgaat cctgcataga
    16921 tgacaacgta tgctaggatt caggcgtctt ctttttacat aaaaagcaag taagcttcct
    16981 tttgttttgc tatatcaggt tttatagtca agcattttgg ttgacgatga acgtgaactc
    17041 gcactcacag acttttttat catctacata tgctgcagat aacgctgtac cgactgatcc
    17101 cttcattttg gtgatttcaa aatgacattt cagcacatct cctggaacaa ctttttgacg
    17161 gaatttggcc ttattgatcc caccgatata agctcttttt cctagaaact cttctgattt
    17221 taggataagt atcgaacctg cttgtgccag tgtttctaga atcaacgcac ccggcatcac
    17281 tggattgtca ggaaagtgac cttggaaaaa atcttcattg attgttacat tttttgtcgc
    17341 aacgatcttt tttcctggtt ctaaagtatc tacataatca atataacaaa taggataacg
    17401 attaggaatc aattccatta cttcagtagc agataatacg taagacataa ttaaactcct
    17461 tctttcaggc aattgccatt ttcattactt tgactatcaa agtatcatat tcctaaatat
    17521 ttagcaatct ttttttaatt taagaaaaaa tagtttgaca atcaaaacat tttgactaat
    17581 aattaagaaa tcaagaagtt attttagcta ttattctcta tttttttacg actatcaaat
    17641 ttttatcaga aacaaaggag agtcattatg tcatttctag aaggaaaaaa aatcgtcatt
    17701 atgggcgtcg ctaacaaaaa aagcattgct tggggttgtg ctgaagcaat gttgaaacaa
    17761 ggggcagaaa ttatctatac ttaccaaaat gaacgaatga aaaaatcatt agtcaaattg
    17821 gtcggcgaag aagcattcac tgtagaatgt gatgtttcta gcgacgaaag catcgaaaaa
    17881 gcaatgaatg ccatcggtga atatgctggg gagatccacg gccttgtcca tgcagttgct
    17941 tacgccaaca aagaagaatt gtccggaaat gtgtctgata tttccagaga cggctatcaa
    18001 ttagctcaag atatcagcag ctactcttta attgctgtat caaaatacgc acaaccgttt
    18061 cttgcaccaa acagcgggat cgttagcatg acttatctag gttcagaacg cgcaatcccg
    18121 aattataaca tgatgggtat tgcgaaagct tctcttgaag ctgctatccg ttatttggca
    18181 gctgagttct cgcctaaagg aattcgggtc aatggaatct cagctggggc aatcaaaaca
    18241 ttagctgtca caggtgttaa agactatcaa aaactgatcc agttatctga atctcgtacg
    18301 cctgatcagc aaggtgtgac gatcgaagaa gtcggtaatg cttgtgcttt cttaatcagc
    18361 ccactttcca gcggaatcat cggtgatatt atctacgttg acaaaggtgt ccatctttca
    18421 taaacttttg ttgcattctt taaagtaaaa catataaaaa tcaggaaaaa actttttaaa
    18481 gtctcttcct gattttttct ttttacgttt ttttcaactc attactttga aattattcca
    18541 cgacttcaat ccagccttct ggtgcttcta tgtctccaaa ttgaatacct gtcaattcat
    18601 catacaaccg ttttgttact ggtcctactt ccgtttcact ataaaataca tgaagattgt
    18661 tattgtgata aatcccaccg attggagaaa taacagccgc tgtaccacat gcaccagctt
    18721 ctgcaaattg atctagatca tcaatgaaaa tatctccttc aattgcttgc agtcctagtc
    18781 gttcttcagc taactgcaac aaggaatatt tcgtgatact tggtaagata gagggcgatt
    18841 gcggagtgat gaattttccg tcttttgtaa ttccaaagaa atttgctgca cctacttctt
    18901 cgattttcgt atgtgtggct ggatcaagat aaacacaatc tgagtaatcc agttcttttg
    18961 cttctgttcc tggaagtaaa ctcgctgcgt aatttccgcc gacttttgct gcaccagtcc
    19021 ccttaggagc agcacgatcg taatcagata caataaaatt cgttggtttt agtccacctt
    19081 tgaaatacgc tcctactggc gtacagaaga cgacaaataa atattctgga gctggatgga
    19141 caccaatgtt ttcaccgacc ccaatcagta aagggcgcaa gtataatgta gcgcctgttc
    19201 catagggcgg cacaaaatct tcatttgctt ttaccacttg cttgacagca tcaacgaaca
    19261 tcttttcagg gaccattggc atcagcaatc gtctagcact ttgattcatc cgtcgactat
    19321 tttgttcagg tcgaaagaga ttgaccttgc cgtcttttcg acgataagct tttagacctt
    19381 caaaacattg ctgaccataa tgaagcgctg gagagccttc atgaatcgtc aggtaattat
    19441 cttctgtcaa ttctccttct tcccattgtc cgtctttcca tttggcaata aaacgccaag
    19501 gagttttgat ataagaaaaa cctagattgt tccaatcgat ttgcatatac ttaccacctt
    19561 cgttattttc tccacatttt atcattatcc atattatttg tcattttatt ttcagctttt
    19621 ttccttcatt atagttattt ttgctatttc cttttttgaa aacttcttgg tacaatacag
    19681 aaagaatcaa attttagaaa agaggatttt atgttttcat tattagcaac tgccggtacg
    19741 acagactctt ctggcgagac attgacagat caagctgtca gcaaagtaaa tgcgtttcag
    19801 cggttttggg acgggattga ttgggacgcc attttggctg cctttatcca aaaaagttta
    19861 tatctgattt ttttgatcgt ccttttttgg attcttcacc gtgtgggaaa atatctgatt
    19921 gataagtctt ttaatcagta ttctaaaaaa gccattctaa acgagagccg cttaaagact
    19981 ttacatagtc ttttaaatac tatttttcat tatacccttg gtttcttttt tatctatgca
    20041 attttatctg ctatcggtgt gccgatcgga tcacttttgg ctggtgccgg aattgcaggt
    20101 gtggcaatcg gtcttggtgc ccaagggttc atgagtgatg ttattaccgg attttttatt
    20161 atcatggaac aacagatgga tgttggggac tacatcaagc tagcaaactt aacgattgaa
    20221 ggaaccgtcg tatctgttgg tatccgtacc cttcagctga aagcaacgga tggtactgtc
    20281 catttcatcc cgaatcgaaa catcaccacg atcagcaatc tctctcgtgc aaatatgcaa
    20341 gtacttttag atattcggat tgttcctgaa gaaggatatg acaaaatcta tgagatcatt
    20401 gatcgagtaa atcgtacatt agctgaaaaa taccaagaag agctccaaac tgaaccttct
    20461 atctttggat tagtggatct tggaaacagc aattttgcga ttcgtacggt ctgctacgca
    20521 ttgaacggaa aacaatatgc cttaaaagaa gagttcttga gctcctatgt caaagaattg
    20581 acagcttctg gtttcacgat tccgaacagt ccaattgctg tcggaaaata atttggacaa
    20641 acgatgcaac gaatctcact aaaaagagcg tgggacaaaa gtaaagaaca cttttgtccc
    20701 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    20761 ttcacaaaaa tttgaaaagc aattttcgtg aattccttct tatttcttgg agttaaacgc
    20821 ttttgtccca gcctcttttt caagataaag tcaaaactgg tacgctgttt tttctactta
    20881 ttttttgatt atcttttagt ttctcgttct ttagctcacg atatcgattt gttcttttaa
    20941 ttcttcgatt ttcggagaca atatattacg acgttctaat tcatgcacca tgaagtttac
    21001 ggctttaagc agctcttttc ttgtaatgat tcctttgaaa atccgatctt ctgtgacaac
    21061 cggtaaaaaa ggcgaatcga ctaacaaatg gagtacttct tctagttccc aattttcatc
    21121 aattgtcgga acatctgttt ctgtcacatc agcaaccgtt agtccttcta acgggtccat
    21181 gctgattgtt tgcaagtcaa tcattttatt gaccacatct gataaactta ctagtcctac
    21241 aaagtgatca tcttttccta atacaggaat tttggaataa ccgaccttcg ataacacaag
    21301 taaaccatgg gacaatggat gatgatacat aacatttgcc acattttctg caggaatcaa
    21361 aaacgtttcc tgattttcca gcagcatttc tcttactata ggtccaatca tctgatggcc
    21421 tccatttcta tttcattcaa cactactatt ttaccgaaac cggatgcaaa attcataaaa
    21481 taaagcttat ttttattaaa aattagagtt tttttattca gcgctctctc gaaaaagaaa
    21541 aggccaactc ttcaactgcc tgatgggcac ggttatagta ttgaacagaa atttggtcat
    21601 ctaaactttc gataagagca tatgatggga tttggatcgg gcctctaggc tgagaaatgc
    21661 taccaggatt caaaaacagg attttctgat ccatctcaca gcctatttga tgggtatgac
    21721 caaaaaacac catatcggca gttgcagctc gagcttcgat tgctaactgt gtcaaaccaa
    21781 atcggacatt cgataaatga ccgtgagtca tgaatactgt atcctgacca gtttggatca
    21841 cttttttctg ttcgaatcct ggtccataat cacaattacc ttgaaccact tggaatgtat
    21901 cccataatgg gtcagaagct tctaattccg aatcaccaca atggaaaaag atatccactt
    21961 cagaacgata acgatctact aagtcaacga ggatatctct gtctccatga ttatcactta
    22021 ctactaaata ccgcatctat ctctctcctt ccagccattg tttccactcg gcactcaatt
    22081 ttttcattgc ttgagcccga tgactgatct tgtttttttc ttcgctcgat aattctgctg
    22141 ctgtttgttt cttaccttct gggataaata aaggatcata cccaaagcca ttttcgccag
    22201 atggtatacg ggctactcga ccgggccatt ccgcttctac tacaaggctg tcttttttgg
    22261 gtgccgcgaa tactaacgta caatggaatt gtgctgttct tttttcatcc ggcacatctg
    22321 tcaattcata taataatttg gcgttattcc ccgcatcact tttttgttcc cctgcaaaac
    22381 gtgcagaata gattcctggc ataccgccta aagcatccac tttcaaacct gaatcatctg
    22441 ctaagactgg ctgatcaagc aattgtgcaa tcgtttctgc ttttaatcgg gcattttctt
    22501 caaatgtgct gccagtttct tccacatctg gcaattcagg atagtcaagt aatgttttta
    22561 catgatatcc cgcttctttg aacatatttc gaaactcttc tgcttttcct ggatttcttg
    22621 tcgcaatgat gattgttttt gtttcttcta tccgctcatc attttgagca aactctgtta
    22681 gcaaagcatg tttttgctct ttgatcaaat cttcaatcgc gttttttcca aaaaagagca
    22741 tttcattcaa ctgttcacca tcaaacgttg cttcttctcc agttccttga atctccacga
    22801 attttccaga ttctgtcatt acaagattca tgtctacaag tgctgcggaa tcttcttggt
    22861 aatccaaatc tgtgacgcaa gtcccatctg gtaagattcc tacgctaact gcagcaagat
    22921 gttcttttat tggatcttct gacaattctt tttctcttaa aagtttttca atggctaatt
    22981 tcaatgccac aaatgcccca gtgatacttg ctgttctagt accgccatcc gcttggatca
    23041 catcgcagtc tacgatgata ctacgttctc ctaatttttc caagtctact actgcacgca
    23101 aggaacgacc aataagacgc tggatttcca ttgttctacc agaaagtttc cctttgctgc
    23161 tttctctacg atttctcgta ctcgttgctc gaggcagcat actatattct gctgtcaccc
    23221 atcctgttcc tgtttctctc aaaaaagggg gaacagaatt ttctattgtt gcagaacaaa
    23281 taactgttgt atcaccaaaa cggatcacta ccgatccttc tggatatttg aaaacatttg
    23341 tttgaagctc cagtttgcga agctcttggg cttttctccc gtcatgacgc atccttattt
    23401 tcctcccaat tcgatatgtt ctacatttaa gtgtccgatt ccaagccagt cttcagctat
    23461 ttcctcgaaa agtttggcag agccagttgt ataaaactgg cataatgtcc gaccattttg
    23521 cggtgaattg ctcaaattga aataatctaa cagcatagat acttcaccta ctgtttctgc
    23581 tccagaatcg atcagttgaa cattttctcc cattacattt tgaatgatgg ggcgtaataa
    23641 tggataatgg gtgcatccca aaatcaatgt atcgattttt ttagtggtta aaggagctaa
    23701 tgtttctgcc acaatttttt tcgccaccga tgaatggtat tcattacttt cgacaactga
    23761 aacaaatttg ggacaagcaa gacttgtcac agtcaattct ggtactttct ctttcagtgc
    23821 tttttcataa gcttgacttt ttaccgtacc aatcgtaccg ataatgccaa cttgtttatt
    23881 ttgtgttttt tttactgccg ctctagtacc gggaaggatc acaccgatga ctggaataga
    23941 aagagcagct ttgatttctt ctaaagccac cgcagttgcg gtattgcagg cgatcaccag
    24001 catcttgatt ccttgctcca ccagataatc cgtcatttcc caagtatact ggattacctg
    24061 ttccgcgggt ctagggccat atgggcagcg tgctgtgtct cctacaaata aaatattttc
    24121 attcggtaat tgtttcaggg cttcttttac tacagtcaag ccgccgacac ctgaatcaat
    24181 aaatccgata gggcgattat ctgtcaatcg tatcatcctt tttttcaata aattctatcc
    24241 tccctattgt gtacttttta gcgtgaattt tcaagtgctc ttacttgctt aaaacaatcg
    24301 aaatctcttt ttttcgaatg gaaagaggaa aagcggttgt gacttta
//
LOCUS       DAZKPE010000040        24342 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000040 DAZKPE010000000
VERSION     DAZKPE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.040"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..787)
                     /locus_tag="ACG930_001774"
     CDS             complement(53..787)
                     /locus_tag="ACG930_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFQ0518932.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ACG930_001775"
     CDS             1114..1524
                     /locus_tag="ACG930_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFQ0518933.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="ACG930_001776"
     CDS             1517..2218
                     /locus_tag="ACG930_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFQ0518934.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="ACG930_001777"
     CDS             2218..3804
                     /locus_tag="ACG930_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0518935.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="ACG930_001778"
     CDS             3823..4044
                     /locus_tag="ACG930_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFQ0518936.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="ACG930_001779"
     CDS             4041..4802
                     /locus_tag="ACG930_001779"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFQ0518937.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="ACG930_001780"
     CDS             5182..5691
                     /locus_tag="ACG930_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFQ0518938.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="ACG930_001781"
     CDS             complement(5766..6305)
                     /locus_tag="ACG930_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFQ0518939.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACG930_001782"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACG930_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFQ0518940.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="ACG930_001783"
     CDS             7318..8169
                     /locus_tag="ACG930_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFQ0518941.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="ACG930_001784"
     CDS             8197..8832
                     /locus_tag="ACG930_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFQ0518942.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="ACG930_001785"
     CDS             8852..9625
                     /locus_tag="ACG930_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0518943.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="ACG930_001786"
     CDS             10033..10830
                     /locus_tag="ACG930_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFQ0518944.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="ACG930_001787"
     CDS             10808..11221
                     /locus_tag="ACG930_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFQ0518945.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="ACG930_001788"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="ACG930_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFQ0518946.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="ACG930_001789"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="ACG930_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFQ0518947.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="ACG930_001790"
     CDS             15998..16558
                     /locus_tag="ACG930_001790"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFQ0518948.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACG930_001791"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACG930_001791"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFQ0518949.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="ACG930_001792"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="ACG930_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFQ0518950.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="ACG930_001793"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="ACG930_001793"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFQ0518951.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="ACG930_001794"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="ACG930_001794"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFQ0518952.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="ACG930_001795"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="ACG930_001795"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFQ0518953.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="ACG930_001796"
     CDS             21905..22483
                     /locus_tag="ACG930_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0518954.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="ACG930_001797"
     CDS             22535..23017
                     /locus_tag="ACG930_001797"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFQ0518955.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="ACG930_001798"
     CDS             23134..23508
                     /locus_tag="ACG930_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518956.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            23938..>24342
                     /locus_tag="ACG930_001799"
     CDS             23938..>24342
                     /locus_tag="ACG930_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFQ0518957.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMS"
BASE COUNT         7978 a         4375 c         5198 g         6791 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa catttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tattaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttttt gagagtataa aatattttgt gtaaatgaaa aaatccatac aaaaaaggaa
    23881 gtcccttctg tagaataaag ttaacgacaa ccaattcaca gaaaagagga cttccctatg
    23941 aatgatttta ctacagaaat tgtgcaaact ctagtcacta aaggcgattt aaatgaatta
    24001 ttccgttcgc acttagaaaa agcgataaac acactcctac ggactgaatt aacggctttt
    24061 ttagattacg aaaaatatga tcgcactggt tttaattcag gtaattcgag aaacggttct
    24121 tactttcgat caatcaaaac cgaatatggt gaattaacat tggaaatacc tagagatcgt
    24181 aatggtgagt ttaaacaaca aactttacca gcctacaaaa gaacaaacga tacattggaa
    24241 accactatta tccatttatt cgaaaaaggt gttacgatgt ctgaaattgc tgatttgatc
    24301 gaaaaaatgt acggtcatca ctatactcca caaaccatgt cc
//
LOCUS       DAZKPE010000041        24267 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000041 DAZKPE010000000
VERSION     DAZKPE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.041"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..2404)
                     /locus_tag="ACG930_001800"
     CDS             complement(59..2404)
                     /locus_tag="ACG930_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFQ0518958.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            2683..3585
                     /locus_tag="ACG930_001801"
     CDS             2683..3585
                     /locus_tag="ACG930_001801"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFQ0518959.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            3798..5573
                     /locus_tag="ACG930_001802"
     CDS             3798..5573
                     /locus_tag="ACG930_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFQ0518960.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5639..7225)
                     /locus_tag="ACG930_001803"
     CDS             complement(5639..7225)
                     /locus_tag="ACG930_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFQ0518961.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            7476..7700
                     /locus_tag="ACG930_001804"
     CDS             7476..7700
                     /locus_tag="ACG930_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFQ0518962.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7841..9592
                     /locus_tag="ACG930_001805"
     CDS             7841..9592
                     /locus_tag="ACG930_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFQ0518963.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            9592..11376
                     /locus_tag="ACG930_001806"
     CDS             9592..11376
                     /locus_tag="ACG930_001806"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518964.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            11702..12553
                     /gene="licT"
                     /locus_tag="ACG930_001807"
     CDS             11702..12553
                     /gene="licT"
                     /locus_tag="ACG930_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFQ0518965.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            12650..14530
                     /locus_tag="ACG930_001808"
     CDS             12650..14530
                     /locus_tag="ACG930_001808"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFQ0518966.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTETAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(14570..15472)
                     /locus_tag="ACG930_001809"
     CDS             complement(14570..15472)
                     /locus_tag="ACG930_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0518967.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDDWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            15703..17106
                     /locus_tag="ACG930_001810"
     CDS             15703..17106
                     /locus_tag="ACG930_001810"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFQ0518968.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            17106..18539
                     /locus_tag="ACG930_001811"
     CDS             17106..18539
                     /locus_tag="ACG930_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFQ0518969.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            18684..19610
                     /gene="trxB"
                     /locus_tag="ACG930_001812"
     CDS             18684..19610
                     /gene="trxB"
                     /locus_tag="ACG930_001812"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFQ0518970.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            19824..21551
                     /locus_tag="ACG930_001813"
     CDS             19824..21551
                     /locus_tag="ACG930_001813"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFQ0518971.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            21566..21916
                     /locus_tag="ACG930_001814"
     CDS             21566..21916
                     /locus_tag="ACG930_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFQ0518972.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(22008..22868)
                     /locus_tag="ACG930_001815"
     CDS             complement(22008..22868)
                     /locus_tag="ACG930_001815"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFQ0518973.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            22960..23388
                     /locus_tag="ACG930_001816"
     CDS             22960..23388
                     /locus_tag="ACG930_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0518974.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            23550..23726
                     /gene="rpsU"
                     /locus_tag="ACG930_001817"
     CDS             23550..23726
                     /gene="rpsU"
                     /locus_tag="ACG930_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFQ0518975.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            23753..24199
                     /locus_tag="ACG930_001818"
     CDS             23753..24199
                     /locus_tag="ACG930_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFQ0518976.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7691 a         4297 c         5199 g         7080 t
ORIGIN      
        1 ataagggact gtgacaatac tattgtcaca atctcttatt actgtgtatt ctattaaatc
       61 aatcatcttt ctcatctgat tctttggttg cttgattcgc tcttgcataa gctgaagcgg
      121 tgttccagta atctgtatag ttttcatcgg taccgccaac gccaaattta aaggcgcttt
      181 tcttcggtcc atttttcgcc catagcgatt caactgtttt tccaggtgtt tggatggatt
      241 ttttattgac agtaactttt ccaggtgttt gaccagtaaa tccagatact tttttcttca
      301 tcacatcaga tgataattcg aatttctcat cagtgccaaa aatgtcaggt tttgcttggt
      361 aagcttgatt gatcagattg gcaagataat tagccgaacg tatccttgct ttgctgtcca
      421 ttccagtatt gtcatcgtgc cctgcccagc tactgatggt aatagacgga gtagagacaa
      481 ttagccatga atctcggtat tcattggtag aaccagtttt tccgacccaa tctgcttttc
      541 ctagatttcc gtttaagctt gagatggcat ctttgaatgg tgtagtgatt tttgcattga
      601 tcacactgcg catcatgtca ttcatgatcg atgccgttgc ttccgaatag atccggacag
      661 agttgctttc gtgtttataa attacatttc ctgcgttatc tgtgatggaa tcgatgatat
      721 agccttcttc atagacgccg ccgtttgcta aagcctgaaa tccattggtc tgttgaagcg
      781 tcgtgacatc tactgtacct aaaggagcag attcaacgcc ccaattgtca tttgccgggt
      841 agttcatctt tgccaagtag tgctcgtaag catattgttt cgatccaccg gaattcaaca
      901 catcttgata taagtgataa gccgggatat tgttggacca ttctagtgac tcacggacgg
      961 tttggaaggt gttcgatcct tcgttagtag cattgacgat tttctcgcca gcattttctc
     1021 cttcttgcca agttgttgca taatctgata cacgggattc tgatccgata agccccatgt
     1081 cgattgcagg tccataaaca agaactggtt tgattgatga gccagcttga cgttctgtat
     1141 cgaaggcatg gttattttga ttctgactgt aattccgtcc gccaacgaat ccgtagatgc
     1201 ggccagttct gttatccatc aatacatttc cggtttctac ttgactgcca gcaccatcat
     1261 ctaacatgta tccataattt tctacgccat tttgcaatgc agcatagaca tctttatcga
     1321 ttgtcgaatg gattgtatat cctttatttt ggattgtttg ctgtgccttt tgataataag
     1381 cgtcactgac cgatgaatca gacatatcag cgttgtcttt ttcagccaat tgttgtgcaa
     1441 tgattcttgt tgcttcattc atcacagtat aatacaagaa ttctctgtca gtctgttctg
     1501 cgatttgttg tggtagaaag tcttttgtaa ggtcataggc ttttgcttct tcgtattgtt
     1561 ctttcgtaat ttggccttca cgatacatac tgaataaaac aaaatctttt ctggcaaggc
     1621 cggcagaaag atcttctttt agcgcacctg tgttcgtgta tggactatac gtgatcgggc
     1681 tttggggtaa tccagcgata taagcagctt gcggcagcgt cacatctttt gcatctacac
     1741 caaagattcc tcttgcagct tcctggactc cagcaatgtt ttgtccctta ttattacgac
     1801 caaatggtga gacattcaaa tacgtagcaa tgatctcatc ttttgaaaag tatttttcta
     1861 cttgtgcaga aagaatgatc tcgtttgctt tacgtttgaa tgttgtttca tctgtaagga
     1921 tctgctgttt gactaattgc tgtgtcaaag ttgatccacc agaagagcca ataccagtag
     1981 cttcagatac taacgctcgt aaaacagctt taggaacgta accttggtgt ttatcgaagt
     2041 attcatcctc tgtgctgata attgcagttt tcaataaagg tgaaatttta tcagatgaaa
     2101 tagtcgtgcg catcagatct gtctggattt ttgatatctc tgtattatct gcataaacaa
     2161 tctttgacgt ttctgtaatg tttcctagtt ctgtctgcag tgctttttta gtcggcaatt
     2221 gtgtgtcttc gacgagatag gcaaaatagc cagcgcctat tccaatacct agagctgcga
     2281 acatcaaaag aagaacagta ataaaaacag tcaatgattg aaaaactcta aaaataatct
     2341 taggaacaaa ccatttttct ttttttcttc tattctgttt ttttcgagta tttttgcgtg
     2401 gcaaaagggt cacctcaact aatggtttta tttcgctaat tatagcaaat aatagaacaa
     2461 aaaaacagac aaggctgttt ttggcaggaa tttctttttt aaaggagtta aaacgtgaga
     2521 aaatgatctt ttttataaaa gagttcttaa gcttttcttt agagaaaatt tcagttacta
     2581 tggagaacag ggcaaagaaa aatcaatcat tttctttgta tatcatctta ccaatatata
     2641 ggaattgtta gtaacaattg cctttcaagg aggaatccat ccatgttatt aggctcacac
     2701 gtcagcatga gcggaaagaa aatgctgtta ggagcagcag aagaagcagc cagttatgga
     2761 tcttcgactt ttatgatcta tacaggcgcc cctcaaaaca ctagaagaaa agccatcgaa
     2821 gagatgaata ttgatgccgg aaaagcgtac atggcagaaa acggtctaac aaatatcgtc
     2881 gttcatgccc cttatatcat taatttgggg aatacgatca aaccagaaat gtttcctttt
     2941 gccgtccaat ttctgagaga agagattgtt cgtgcggaag ctttaggcgc tactcaaatt
     3001 acacttcacc caggtgctca tgtaggggca ggaacagaag ccggaattgc tagaattatt
     3061 gaaggcttga atgaagtttt gacaaaagaa cagacggcac aaatcgcttt ggagacaatg
     3121 gcaggtaaag gtacggaaat cggtcgaaca tttgaggaat tagcgcaaat catcgatgga
     3181 gtaaaattga atgaaaaatt atccgttact tttgacacct gtcatacgaa tgatgccggt
     3241 tataatatta aagaagactt ttcaggtgta atggaagagt ttgataagat catcgggtta
     3301 gatcggctta aagtactcca tatcaatgat tctaaaaatc cgcaaggttc gcataaagac
     3361 cgacacgcca atattggttt tggaacaatc ggattcgaca cgctgaataa gatcgtccat
     3421 gatccaatgt ttgacaatat ttcgaaaatc ttggaaactc cctatgtcgg caaagataaa
     3481 aagaaagctt acgcaccata tggaaaagaa atcgccatgt tcaaagcaca aatattcgat
     3541 ccagaagtgt ttcctgagtt attagcagaa gaagtgatac tctaagattt tctatctgac
     3601 agcagcaaaa aaggaccagg cacattgcct tgtccttttt tgtttaagaa acaaaggagt
     3661 gctttttgca gtctttttca tcatgcatct tctcccccct ctttttaaat ttagacaaac
     3721 agggtatact ggtagaaaag taaaaaaacg aaaagtttca caagcaagtg gcaaaacgtg
     3781 attggaagga cgaaaagatg ctgaacactt taaaaccctt gatcaaccaa ctaaaaaaga
     3841 aacatacata ctttattctt ggcatagccc tattatttac aattattcgt ttgtatttat
     3901 atagtaaagc aatctatgga acagacatgt cggcaaccta tgatgaccag ctgctgattc
     3961 gctatgctca aaatattttg gacggtaaat ggctagggga gtatacgact acaacacttt
     4021 ccaaaggaat ctcctacagc ttatttttag tacttgcaca taaactgcat ctttcttatg
     4081 cagttttgtt cggcatgttc agtatttttg ccagtatatt ggttgcactc gcgtttaaac
     4141 cgatcgtgaa gaacaagtat cttcttttaa gtttctattt ttattttttg ttttctccga
     4201 ttagttttac acatgaatat tccactcgaa cgtatcgtaa tgccctcgtg attccggctg
     4261 ttgagatcat tatcgcttgt ttactagcta tttattaccg caaatacggt tctagcagaa
     4321 aattgctgcc atggttttta gggctttctg tcgcttttcc tttcttttgg ttcattcgcg
     4381 aagattctat ctggcttctt ccttttactg tagtagcttt gggtatcagt ttcgtccaga
     4441 tcttgctagg gcaagacttt tctttcaaag aagtaaagaa gttaaaaaaa cgactctttc
     4501 ttctctcgaa acgggaatgg ctgaaacttt cattgttttt acttcctata gttggctttt
     4561 ccatcgtcta tcagtggatc gaatataaaa atgagacaac atacggtatt gcaaccatca
     4621 atgaccgttc cagtggagaa tttggacgtt tgatgaaaca actgatccga atagatgatg
     4681 aaacgaactt gaataaagaa aacagtgaga tatgggtctc acatgctgca ctaaataaag
     4741 cattagccgc atctcctaca ttccatactg tttctacccg tattgacgaa ttatatacga
     4801 ctcacgcgtg gactcaaggt ggaaaagtaa aagaattacc cggagatatc atcttttggg
     4861 cattgcgaga tgtggtaagc gaatctggtt attaccaaaa caatgcaaaa gaaaccaatg
     4921 atttttggaa aaaagtcaac caagaattag aagaagccta tcacaaggga accatcaaaa
     4981 agaaaaaaga gttctatctg atgggatcag gagatggaaa gacgatgagt gatctaccaa
     5041 tcgtattcga tttccttcaa tcaggatacg cttatgcatg gcgatataaa gatttccatc
     5101 aaggaggaaa ttatagtttc ggaacgcaag aacaagtcaa acaggctcaa gaattattaa
     5161 accttccgct aatggagaat tggatcgata gtaatgaacc gagaacacct aatttccaat
     5221 taacaaaatc agcaaaagtc gcgaatgtca tcataaaaat ttaccaagtt ctggctattc
     5281 ccgtgctgat tgcttcaata gcagggatat tacttatgat actaggaacc gtatttgcaa
     5341 aagctgatcg tgcctattat agttcctctt tgattgtggt caccggatta atactgacac
     5401 aattggtttt tcttttcggt gtctcgtggt tttgttctta tgcgccagaa aaaaaggatt
     5461 attttttaag tgtctacact ggcgcaggcg tgccgttaac gcaattcatc gtagtaacaa
     5521 gcatgctagt tttcagtaaa ttaaatctga aaaaagcttt atcttctaaa taaaaagacc
     5581 cttggtagct agatttttaa cctaactatc aagggtcttt gtgtggaaaa atcagttttt
     5641 attcgatttc ttctaccatt tcctgcaaac gctgttcata ttttttgttt cctttatata
     5701 aatcaccaat cgtccatgcc aacaggagga ggacaagaac aatgattaca taagcgatgt
     5761 gatcagccaa tgctagttga gcggaagtgg cttgctcgcc gaagaaactt tcgatctgtc
     5821 ctggtaatcc tcgtaagttc aagtaagtta gactaatcac agagaaccag ccaagaagtt
     5881 ttacgatgaa tgaattttta aatcggctac ccatctccgc ttggctgttg gtcatcatca
     5941 gtaaagggat catcgaaaac ggcaacgcaa aagccaagaa cacctgggat tcattcatta
     6001 agttattcaa agcggtatgt tcttcgatcg ttccttttgt acttgtaaac aaaacacaaa
     6061 tcaatacagg aatcacagaa agcaatcgtg tgaccagtct tcttagccaa atcgggatac
     6121 gcatatggat gaatccttcc atgatgactt gaccggtcaa cgtaccagta atagtagagt
     6181 tctggccaga agcaagaagt gctacagcaa ataaagtgga caagatacca gattttgcta
     6241 cagcaatcaa gataccattg ctcatagctg atggatcaga taaagcttca tacagaccaa
     6301 aaaaggaagg atcttgaaca gaaccggttt tgaagacagc gacacccata atcaatagca
     6361 gcgcattgac tagaaaagcc atcgacaatt ggatattaga gtcccaagta gaaaaacgta
     6421 cagcttgtgc tacatcttct tcgtcttggt gatcgatctt ccgagtttgt gaaactgctg
     6481 aatgtagata taagttatgt ggcatgactg ttgcgccaat aatccctaat gctccagtta
     6541 gcggagtttc gccaccaatg acaggtgagt cggagaatgt atggctgtta gggataaagc
     6601 cagcaaataa actgtgccaa tctgggttag acaagccaac ttgatagaca aaaacgaata
     6661 aaatgacgaa aatcaagcag acaaccagtg cttcgatctt acgaaacccg acttttgtca
     6721 gtagtaagag aacgaaaaca tctaatacag taataaagac ggcaatcacc aatggaatat
     6781 caaaaagtaa gtagagggcg attgctgcac caatgacttc tgcaatatct gttgccataa
     6841 tggctaattc agtcaagatc cataaaatga cacccaatgt cttacttgtg cgtgctcgga
     6901 ttgcttgggc caaatccatt tgggtcacga ttcctaattt tgctgccata tactgtaaaa
     6961 gcatagcaat cagactagac atcaaaataa ctgacatcaa taaatattgg aaattttgtc
     7021 ctccggtgat cgaagtagac cagttacccg ggtccatata cccaactgct actaacgcac
     7081 caggtccaga gtaagcaaga agtgttttaa aaaaactttt cccctttggt acatccactg
     7141 ttccatttac ttcagctaaa gataaaccat ttgtatgttc aataagtcga tgcttatgaa
     7201 attgtttgtt ggattgatta ttcaagaaaa aaccaccttt cctatttatc tacgattaca
     7261 ttctacacct caaaaagaaa aaattaaaga aaaagattcg gtatgcctaa ttttttttcg
     7321 tggcgtgtct tgctagatga cgaaagaaat tttgttctcc tctaaaaaaa ccactatttt
     7381 ttgcatgaaa ctaaagaata cgcctttctt ttttcaataa actttagtaa aataagtcat
     7441 tgagagcaat tcggaaatag aaaggagaga tttatatgtt atcaacaggt attgtcgtac
     7501 ttattgctat tattgctttg ctaatcggcg cagtaggtgg ctttttccta gcgcgtaaat
     7561 atatgaaaga ctatttagaa aaaaatcctc ccgttaatga ggacatgttg cgatcaatga
     7621 tgatgtcaat ggggcaaaaa ccatctgaga agaaaattcg ccagatgatg cagcaaatga
     7681 agaaccaagg gaaaaaatag gttctgaccc aacgactttt tacgggctga ttttttcagt
     7741 ccgtttttta tttcgtaatt tgttagacta ttcagattat tcagcaaaaa gacaagcaca
     7801 gacaatccta ggctcttgat aaagacaaag gaggagtaaa atgtcgattt ttagaaagtt
     7861 aggctggttt tttcgtcagg aaaagaaaca ttatttaatt ggggttttct cgctattcgc
     7921 agtggccttg gtacagttag ttcctccaaa agtgattggg atcatcattg atgagattgc
     7981 cgataaaaat ttatcagtaa agatcatttt cgggtggatc ttcctattga ttatcgctgc
     8041 ttttttacaa tatctttttc gttatatctg gcggacgaat atttggggaa gtgcagctcg
     8101 gttggagaaa gaacttcggc agcagttatt caaacatttt acagaaatgg acaatctctt
     8161 ttaccaaaaa tatcggactg gggatttgat ggctcatgca acgaatgatt tgaatgcgat
     8221 ccagaatgta gcaggagctg gtatcttgac ctttgcagat tcagtgatta cgggcggaac
     8281 aacgatcatt gcgatgattt tgtttattga ttggcgctta acactgattg cgctgattcc
     8341 tctgcctttg ctggccgtca cttcacgagt gctggggtcg aaactccatg atgcttttcg
     8401 tgattcgcaa gaagcttttt ctagtatcaa tgataagaca caagaaagta tcactgggat
     8461 caaagtcatt aaaacatttg gacaagaaaa agaagatcta gcggattttg aagaaaagat
     8521 tgaagatgca attattaaaa acaaacgagt caatttttta gactccttat ttgatccatt
     8581 cattaccttg attatcggtc tgtcttatgt tgcaacaatt attttaggtg gaaagtatgt
     8641 cttggaaggc acgatctcga tcgggcagat ggtctcattt attagttata tcggtatgct
     8701 tgtttggccg atgtttgcga ttggtcgatt gttcaacgta ttggaaagag gaaatgcttc
     8761 ttatgatcgc gtcaatgaac ttttgcatga aaaaacgcat atcgtggaac aactgggtgc
     8821 agtgcagacc ccggcaaaag gcgagctgaa tgtagctatt tcctctttta attatccgaa
     8881 agaagaatca ccagcattag aacaaatcaa gtttgcaatc caagaaggag aaacattagg
     8941 tattgttggg aaaactggtg cgggaaaaac gacgatcatc aaattactga tgcgtgaata
     9001 cgatgattat caagggaaaa tccaatttgg cggacgttcg atcaaagaat attcattgaa
     9061 tgctttatta ggatcaatcg gctatgtgcc tcaggatcac ttcttgtttt cgatgaccat
     9121 tcgagataat atccgttttt ctaatccaaa actttcagaa gaagaagtag agcatgcggc
     9181 ttctttagca tttatcaaca atgaaatcaa ggaattacca aaaggttatg ataccttagt
     9241 tggagaacgt ggagtctctt tatctggcgg acagaaacaa aggatttcga ttgctcgagc
     9301 attgatcaaa aatcctgaat tattaatatt agatgatgca ctttctgcag tagatgccaa
     9361 aacagaagaa gctatcttgc ataatttaaa agaaataaga aaagagaaaa caactatcat
     9421 ttcagctcac cgtttaagta gcgtgatgca tgcaaaagaa atcattgttg tcgatcaagg
     9481 gaaaatcatt gaacgaggaa cccatcatga gctgcttgca ctaggcggct ggtatgaaca
     9541 aatgtgggag aaacagcaat tagaagcgaa gatagaagga ggcgaggcct gatggatgaa
     9601 aattatcaat cggaatggac aaaatcgatt ccacttaaag aacagaaaaa gatcatcaaa
     9661 cgactgatga agttcgccaa accttttaga agaacgttca tcgttgctat cttatttgcg
     9721 tttgctctgt ctgtgatcaa tgtcctattg ccaaggatca tccaaacttt tatggatgat
     9781 catctggcta aacagtcggc tacgacacaa gttattttgt tttttgctgg tatgtactta
     9841 tttggagtca tagtaaaaag tatcatttgg tttttccaat ggtatttgta ttccatggct
     9901 tcattgaaga cctatcagta tattagggta aaattatttg aaaagctgca tacactaggt
     9961 atgcgttatt ttgatcagac accggcagga tcaaccgttt ctcgagtgac gaatgacaca
    10021 gaaacgctat ttgaattttg gtacgtcttt ttgatggtat tgactgggat ctttgcagtc
    10081 gtttcttcat tcattgccat gtttcaaatc aatggagaaa ttgccttgtg gactttggtg
    10141 ttcttgccaa ttttaggaat agtcatctgg tattaccaga aatttagttc tcgtatttac
    10201 cggaatatgc gggaaaaatt aagtcagctg aatacgaaat tgaatgaatc gatttccggc
    10261 atgcgtatta tccagcagtt tcgccaagaa gctcgtttag ctaaagaatt tgaacaagtg
    10321 aacaatgagt atttagacac gcgttatgcg atgatcaaaa caaattcgat tctgttaagt
    10381 ccgatcatca attttctata tgcattggcg attgcgttgg tgttgacttt gtttgggatc
    10441 gatgcgttgc attctcccgt agaagttgga ctgatctatg catttacgac ctatgtccag
    10501 ggatttttta atccaatgtc tcaaatgatg gactttttga gcatcttcac agatgggatg
    10561 gttgctggta gtcgtatctt gaagattatg gatacagaag aatatgcacc acaacaaaac
    10621 cctggagcag atcaaatgat tacttcaggt aagattgagt ttcgcaatgt aagcttttct
    10681 tatgatggag agcacaatgt attaaacaat atctcttttg ttgctaatcc gggagagacc
    10741 gttgcattag tgggacacac cggaagtggg aaaagctcga tcatcaatgt gttgatgcgg
    10801 ttttacgaat tttatgaagg tcagatattg attgatgatc atgacattcg agaatatcca
    10861 atggaagagt tacgtaagaa aatggggctg gtcttgcaag atgctttctt gttttatggg
    10921 gatatcgcag gaaatattcg gatgatgaat ccagctatca cagacgaaca gatacgccat
    10981 gcggctgagt ttgttcaagc aaacaaattc atcgatgaat taccaaaagg atatcactca
    11041 aaagtgatcg aacatggtgc cagctattct agtggacaac gacagctgat cacttttgcg
    11101 cgaacaatcg tgactgatcc taaaattcta gtattggatg aagcaacagc aaatatcgat
    11161 actgaaacag aaggattgat ccaagaagga ttggcgaaaa tgcgacaagg acggacaacg
    11221 attgcgattg cccatcggct gtcaacgatt cgagatgcag aattgatttt agttttagac
    11281 aaaggtcata tagtagaacg cgggaatcat gaaacacttc tagcgcaaaa tggtttgtat
    11341 gcagatatgt acaaactgca aagcagtggt atataaaaga tgttgtgaca gtagcatttt
    11401 gacctaagca ctagagtgaa aataaaacat agcttcccat atttttcatc tgtgagagtt
    11461 agtgtcgtag ttaccagatt taaaaaagac gacgtcagct agtcagaagt gcctaatagc
    11521 ccctaagaaa gcgttgacaa aatcgtttgc tttcgataat ataaagaaaa cgatacaact
    11581 tggatagtga ttgcctgatg caagctaaac ctaatgagtc tcccatggtt tcatggacgg
    11641 ctttttgggt ttttcttttt gttttggata cagccctata tatcatggaa aggagcaaaa
    11701 catgctgatt gagaaagtac tgaataacaa cgtcgtaata acaagggatg aaagagatcg
    11761 ggaaatgatt gtgatgggaa aaggattggc attcaaaaag aaggtgggtg acccgattct
    11821 tgattcatgc atcgacaaaa aatttcagtt gacaaatgac ggactttcac aacagttcca
    11881 agaattggca caagcgattc ctcttgagta cttagaaatt tcttgtgaaa tcattgaata
    11941 tacaaaagag gctctgcaag tccatttaaa tgattctgtg tatatttcat tgacggatca
    12001 cttgtataca gctatcgaac gtcaaaaaat ggggatcttt gtgccaaatg tattgctgta
    12061 tgatatcaaa caactgtttc ctaaagagta tgccattggg aaaaaaacag tgaagaaaat
    12121 ctcggataaa taccacatca agttatcaga agacgaagcc ggatttatcg cattgcattt
    12181 agtcaatgca caaggcattc aaagccagca agacaatacc tacctgttta ccacaacaat
    12241 acaggatatt ttaaatatcg tccgctatta ctataagatt acatttgatg aagattcagt
    12301 ccactttttt cgattcgtca cacacctgcg tttttttctg acacgtgttc tagatggagc
    12361 gaaatcagaa gatggagaag tttctgagga attgttccaa gttgttcaaa aaaaatataa
    12421 ggatacgttt ggttgcgttg agaaaatagc agacttttta accggggctt tcgactacca
    12481 gatgtccacg gatgaaaaaa tgtatttaac gatccatact gcgcgtttag tgcatgagaa
    12541 tcgttgtaaa taaataaaaa aggaggacaa attaacaaga acgtatgaaa ataagggtag
    12601 tgacattcag ttggctaaac cttccactaa ttaattggag ggaatagaaa tgggaaaata
    12661 ccaggaatta gcagaaaaca tcgtaaagaa tatcggagga aaagaaaata tccgtagctt
    12721 gacacactgt gtgacgcgac ttcgtttcaa actaaaggag gaaaataaag caaaggatga
    12781 tgttttgaaa aagatggaag ggatagtcac catcatgaaa agcggcgggc aatatcaagt
    12841 tgtaatcggg aatcatgtgc cagatgtcta tgcagaagta ctgacagtag ccgggatttc
    12901 cgatgaagta gaagaagagg tttcttcaag tagtaatctg ttcaatcgat taatcgacat
    12961 attaagtggc tgtttccagc cttttttagg tgctttagct gcagcgggaa tggtcaaagg
    13021 attaaatgct ttgttcttgt ttctcaaatt ttatactgaa ggatcgggta cgtacatcat
    13081 gctgaatggg ataggggatg caatttttta tttcatgcca gtgatcttag ggtacacagc
    13141 agcgaaaaaa tttcatctga atccgatggt ggggctcgtg attggtgcag cactttgtta
    13201 tccgactgta caaggagcag cactacaaag tggtttccct gatggcagtc ctgcgcctta
    13261 tagcttgctg gggcttccgg cttatgaaac atttttgggt atcccatggg tgggcagcag
    13321 ttataccagt agcgtcgtac ctgttatctt cattatcgca tttgccggac aagtccaaaa
    13381 aattgccaag aaatggattc ctgcagtcgt ccagaccttt ttggttcctt tttctgtgtt
    13441 attaatcgca cttcctgctg gttttttgat tatcggtccg attgtcagta tactgacaga
    13501 tctattaagc acgggattcc aagcattgat ggacttttct ccagctgtgt atggtgcagt
    13561 tctagggttt ctttggcaag tactggtgat tttcggactt cattggagta ttatccctct
    13621 tgcgattatg cagctagcgc aaaatgggtg gagtcagatg ttagtaggcg tttatggcgc
    13681 gagttttgca cagacagcag tggtattggc gatgtatttc aagttcaagg atcaaaaaat
    13741 gaaggcgctt tgcatgccag ctgtgatttc aggaatcttc ggcgtaacag aaacggctat
    13801 ttatggaatc accttaccaa agaagaagcc atttatttac tcgatgattg gtggtgctgt
    13861 ttcaggaatc tatttgatgg catctggaac aatcagctac acaatgggcg ggttagggat
    13921 ttttggggtg gtaaactaca tcacggaaac agacgccagt ggtatgtttc aagcgtttat
    13981 cggcattgct attgcttcgg taatcgggtt ttcgctgact tttttctttt ggaaggatga
    14041 agcaggtgaa acagatgata tacagaaaaa atcaggtaaa gaaattgtaa aaacaccgat
    14101 acaaggacaa atcgctccac taaatgcagc aaaggatgca gcttttgcac aaggaacact
    14161 aggtcgagga atcttgatct accctgaaaa aggagaagta cgtgcccctt ttgacggaac
    14221 agtcatgacc ctgttcccga cgaaacatgc aattggaatg gtttctgaaa cagggctgga
    14281 attgctgatt catgtcggat tggatactgt gcagttggaa gggaaatatt ttgaaagctt
    14341 agtgcagcaa ggagaaagag tgaaacaagg cgatctgttg ctacgcttcg acaaaaagaa
    14401 aatcgaaaag gaaggataca gtttagaaac acctgtgatc gtcaccaatt acacggatta
    14461 tttggatatt ttggaaaacc aaggggagac ggtcgggcca gacgatgcac ttatcaccgc
    14521 actgacctga acggttaggt gaagaatgga ctaggcttaa ctattctttt tattccactt
    14581 ctttattttc aaaattgaaa ggctctttca tgatggctga gctgataggg cgtttatcga
    14641 atttttgacc gacagaaatt agatggacta aattctgttg ataattttct gcaaaaacac
    14701 aactatataa cacgtctaga agataacaaa ttgatgtatt gatcgtaaaa ttaccaattt
    14761 ttgaatacag tcgctcgcgt gtcgtaagtc gcaaagcggc tgtactcatt gcagatagcg
    14821 ttgaatcacc gatactggtc aaagctaaaa ttggaacatc attttgtttc aatatttctg
    14881 cggtacgaag gatcacattg ttttcacccg tataagaaat cagaatcccg cacatatcac
    14941 tcgtgcaatt gtacgcttca tagaacgatt caccaaaagt ggtgacaatc gtgacatcca
    15001 ttttgatgcg cttcattttc agcatgaaat cttgagaaat caaagtattc gagttactgg
    15061 cgaaaatcac gatttttttt gcttgaagca ttagttgttt ggctttttgc agttggtcat
    15121 gatgaatgag agaaagtgta tcatgaatcg tcatctgttc taaagaagcc attttatttg
    15181 cgatcgtcat aataccgtct gtggtggaaa aaggaagatt cgcatctacg tcttgaaaat
    15241 tcccttcaag ataggctgtt tcagctaaaa aagcattacg aaaactgacc cagtcatcaa
    15301 aacccatttt ttttgctaca cggatgagtg tagacgggtg gacatagcat cgctcagcga
    15361 tctcttggat ggtcatttcg ccaagtgctg gagaatcgct taagagaaac tggatcactt
    15421 cattttctga aggagaaaag gagatttctt tgattttttc acgtaataac atgtagttac
    15481 cttcttctta tttttttacg taaattataa cttttttgaa aatgttttgt aaacggattt
    15541 atactatata acttaaaata gacttttttt gacaagatat ttacaaaaat ccactagaaa
    15601 acagtaactt ttgtaaatgt tactggaaag aaacggattt ctattgtttg ttttgtttac
    15661 aaaaaagata atgaaagtgt aaaaaagtaa aggagtgaga acatggcaaa aggaatcaaa
    15721 atcgctacga ttggtggagg cagcagttac acccctgagt tgatggaagg atttatcaaa
    15781 agatatgagg aattaccgat acgagaaatc tggctcgtag atgtagaaga aggaaaagaa
    15841 aagcttgaga tcgttagtca gatgtctcag cgtatgtggg atgcttctcc gtatgaagtc
    15901 aaaatctatg caactctgga tcgggaagaa gcattgaatg atgcggattt tgttacgact
    15961 cagtttcgtg tcggtcaatt agatgcacga atcaaagacg agcggatccc tagttattat
    16021 gggatgattg ggcaagaaac aaatggtgct ggcgggatat tcaaagcttt tcgtaccgtt
    16081 ccagtggtct tggcaatcgt tgaagacatg aagcgtttat gtccaaatgc ttggctgatc
    16141 aatttcgcga acccaagtgg gatggtgaca gaagcagtta tcagatatgg caaatgggat
    16201 aaagtgattg gattatgcaa tgtgccagta atggcgatga tgacagaacc agcaatgctt
    16261 ggcaagaaaa aagaagagct gatctacaag tttgccggtc taaatcattt ccattggcac
    16321 aaagtagcag ataataaagg aaatgaccgc acggcagaat tgattgatcg tttatacgat
    16381 gaagacaatg gattgccgaa aaatatcttt gatatcccgt ttttcaaaga acaattaaaa
    16441 caaatgaata tgatcccttg tggctaccac cgctattact accgtgaaga agaaatgctg
    16501 gaacatgctt tagaagaata tcaaacgatt ggtacaagag cgcagcaagt gaaagaaaca
    16561 gaagcagagc tatttgaatt atacaaagat ccagaattag accataaacc tgaacaattg
    16621 caaaaacgag gtggcgctta ttattcagac gctgcctgtg aaacgattgc ttcaatctat
    16681 ggaaataaag aaacacagat cgtggtatct acaaagaatg atggagctgt tcctgacctg
    16741 ccggcagatt gtgtagtaga agtcactgcc tatgttggcg cacaaggagc gagaaatgta
    16801 gcgtttggtt ctcttcctgc tgctgaaaga ggctggttgc aagtaatgaa gaatatggaa
    16861 ttgctgacga tcgaagcagc tgtgactggt gattatggga cagctttaca ggcgtttacg
    16921 atcaatccgc ttatacgatc aggaaagaca gcaaaacgga tcatggatga gttgtttatt
    16981 gcacaccagc agtatttacc gcaattcaag gaaacaatca gccgattaaa agaagaagga
    17041 atcgaagttc aagatgaact ggcaagagaa ttatcaggta atacacatat aatggaggaa
    17101 gtataatggg attcagaaaa gattttttat ggggcggtgc tacagcagcc aatcaatgtg
    17161 agggcggtta tgatgaaggt ggacgcggac tagcaaacgt agatgttgtg ccaatcggaa
    17221 aagaccgttt tcctgttatc accggaaaga aaaaaatgtt tgaatttgat gaggatcatt
    17281 tttatccagc aaaaattgca atcgatatgt atcatcgtta taaagaagat attgctttgt
    17341 ttgcagaaat ggggttcaag acttatcgaa tgtccatcgc ctggagtcgt atttttccaa
    17401 tgggggatga aaaagagccg aatgaagctg gcttgaaatt ttatgaggat gtctttaaag
    17461 aatgccaaaa gcacggaatc gagccacttg tgacgattac gcattttgat tgtccaatgc
    17521 atttgatcaa agaatacggt gcgtggcgtt ccagagaact cgttggtttt tatgaaaatc
    17581 tgtgtcgagt catcttcaat cgatataaag gacttgtcaa atactggctg acattcaatg
    17641 agatcaatat gatccttcat gcaccattca tgggagcagg actgtacttt gaagaaggag
    17701 aaaacgaaga acaagtcaaa tatcaagcgg cacatcatga gttggttgca agtgccatcg
    17761 caacgaagat tgctcatgaa gtagatccgg agaacaaagt aggctgtatg ctggcagcag
    17821 gagcatatta tccatacact tgcaatcctg aagatgtttg ggcttctaga aaatcagatc
    17881 gagaaaatta tttcttcatt gatgttcagt cacgaggaga atacccagct tatgcattga
    17941 aagaaatgga acgaaatggc attcagatcg aaatggaacc aggggatgcc gcattgctga
    18001 aagaacatac tgttgatttt atctcttttt cttattattc ttcccgagtt tcgactaccg
    18061 acaacgaact cttggaacag actgcaggaa atatctttgc ttctgtcaaa aatccatatc
    18121 tgcaagcaag tgaatggggg tggcaaattg atccattagg cttgagaata acgatgaatg
    18181 atatttatga tcgttatcaa aaaccattat ttattgtaga aaacggctta ggtgcagtcg
    18241 atacgccaga tgagaatggt tatgtggaag atgattaccg aatcgattac ctggcagcgc
    18301 atatccaggc gatgaaggat gcagtagaac tagacggagt cgatctatta ggctatacga
    18361 cttggggatg tattgattta gtatcagctg gtaccggtga gatgaagaaa agatacggat
    18421 tcatttatgt cgatcgtgat aaccaaggaa atggcacatt agcccgttca aagaaaaaat
    18481 cattcaactg gtataaaaaa gtaattgatt caaatggaga aaatctttcg aacgattgat
    18541 caatgattta taaaagtcta ttgtttttca gcggattttt cgagtataat aaagctattc
    18601 gagaaacgca agcagaacaa tagacttttt ttcgcattgg ctgtaaagta tgcttacttg
    18661 attaagtaaa ggagaatcta catatgtatg atgtaatcgt tattggcgca ggtcctgctg
    18721 ggatgactgc tgctttatat gcttcacgtt caaacttatc cgtattgatg atcgaacaag
    18781 gtgcccctgg cggccaaatg aacaatacgg cagaaatcga aaattatcct ggattcgatt
    18841 cgatcatggg ccccgatcta gcttataaga tgtatgaaag tgtctcaaga tttgggacag
    18901 aaaatgctta tggaatcgtt caagatatca aggatcacgg cagccataaa gaagtcatct
    18961 gtgaagataa aagttacgaa ggaaaaacag tcattatcgc aacaggctgt atccaccgta
    19021 aattaggcgt acctggcgag gaagaatttg ctggacgagg cgtttcttac tgtgcagtct
    19081 gtgatggtgc gtttttccgt aacaaacgtc tagtagtcat cgggggtggg gactcagcag
    19141 tagaagaagc catctatttg acacaatttg cttctgaagt agtgatcgtc caccgtagag
    19201 atgaattacg tgcacaaaag atcatccaag accgtgcatt tgcaaatgaa aaaatttcct
    19261 ttatgtggga tacagtcgtt gacgaaatcg ttggaaacga aatggtagtg acaggtgtga
    19321 aagcacgtaa tgtcaaaacc ggcaatgaat ttgatttagc agcagacgga gtattcatct
    19381 atgttggact ggatccatta actgcacctt ttagagaagc aggtttgacg aacgaagctg
    19441 gctggattcc aacagacaac gaaatgaaaa cgaatatgcc aggcgttttt gccatcggag
    19501 atgttcgtga aaaagatttg cgacaaatca ctacagctgt tggtgacggc ggtattgctg
    19561 gacaacaagt gtataaatac ttggaatctt tagaagaaac aactgcataa gtttaaaaag
    19621 agtagaagaa cgggttcaat tgttctttta ctcttttttt tcgcgtgaaa tttactgaat
    19681 ctgatttatg cgaacacgtc caacaccttt tgataaaaga atcctttctt gatttaagcg
    19741 ttttttggtc ctcatacttt catatctaat aagtgaatgc tatacttatt aagaaccata
    19801 tttcagaaag aggtgttatt ttcatgtctt gggaacaagt gtatgaacaa tgggtacatg
    19861 aagaaaattt agaagaaaac ttaaaaaaac aattaaatga tctgggtgaa gatcctgaaa
    19921 aacttgaaga tgctttttat gcaccgttgg aattcggtac tgcaggcatg cggggaatct
    19981 taggacctgg gatcaatcga atgaacatct atacggtaag acaagcaaca gaaggactag
    20041 cacgtttcat ggatacacaa ggtgaagaag caaaacgccg aggtgtcgct attgcttatg
    20101 actcacgcca tcagtcacca gaatttgcaa tggaagcagc caaaacactg gcacatcaca
    20161 atatcccgtc ttatgtattc gaaagtctgc gtccaacacc agagctttct tttgcagttc
    20221 gtcatttgaa gacgtttgcg ggaatcatgg taactgcatc tcacaaccca gcggcttaca
    20281 atggatataa agtctacgga gaagatggcg gacaaatgcc tcctgcagac gcagatgcat
    20341 tgacgaaata tgtccgtgaa gtcagcaatc cgctaaaagt cgaagtatta tctgacgaag
    20401 aagctaaaca tagcgggttg atcacgatca tcggagaaga agtggacgct gcttatctag
    20461 aagaaatcaa agcagtgacg attgatcgtg aattggtaga aacaatgggg aaagatttga
    20521 aacttgtgta cacgccactt catggaacag ggaaaatgtt gggcgaacgt gcgttgaaac
    20581 aagctggatt cgaacaattc gtactagttc ccgaacaagc tgtggcagat ccagatttca
    20641 ctacggtcaa atcgccaaat ccagaagaac attcagcttt tgaatatgct atacgacttg
    20701 gagaaaaaga aggagctgac ttgctgattg caacagatcc tgatgcagac cgtttaggcg
    20761 cagcggttcg tttgccagat ggttcttatg aagtattgac tgggaaccaa atcggggcat
    20821 tgtttgctca atatattttg gaagcacatc aatcaagagg cactttacca gaaaacgcag
    20881 cggtattgaa atcaatcgtt tccagcgaat tgcctacagc aattgcggaa cactacggtg
    20941 ctaccatgtt caatgtgttg acagggttta aattcattgc tgaaaaaatc caacaattcg
    21001 aagaagacca ttcacatact tttatgtttg gattcgaaga aagttatggt tatttagtta
    21061 aaccttttgt tcgcgataaa gacgcgatcc aagcattgct tttattagca gaagtagcag
    21121 cttactataa aaaacaaggc aaaacgttgt atgacggctt gcaaacgatt tttgaaacct
    21181 atggctattt tgcagaaaaa acgatttctg tgacaatgag cggacaagaa ggttctgcga
    21241 aaatctctgc tttgatggaa aaattccgta aagaagcacc gacagaattt gccggagcaa
    21301 aagttattca aacagaagac tttaaagaat tgacgagaac agaccgtgaa ggaaacgtag
    21361 aaaaactaac aacaccgcca tccgacgtat tgaaatatac attggaagaa aatggctgga
    21421 ttgctatccg cccttcagga actgagccga aaatcaagtt ttatattggt gtaaaaggaa
    21481 gctctacaga agacgcagcc gaaaaagtag cctcttatga agcgattatc aaaaagatga
    21541 cagaagaata aaaaacttga gactgatgga aaaagtggta aactttagaa gtcagtcttt
    21601 tttcaagttg gaggtgaatg gattgccaga cacgcaaaaa tcaaaagtag agaaagtcag
    21661 tcaattattc aaaatgttga gtgatcccac tcgtcttaaa attctgctat atctgaaaga
    21721 cggggaacaa aatgtgacag caatcaccca agcagtggaa atggagcagt ctgctgtatc
    21781 gcatcaacta cgtttattaa gagaaaatca tgtcgtcaag tctcatcgcg agggaaaagc
    21841 gattttgtat agtcttgatg attctcatgt actggatatt ttgaaccaga cactcaaaca
    21901 tgtggaacat caataacgat aggtgcaaat agataaacac tggagtgtga caacgaaatt
    21961 tcttcgttgt cacactccag tgttttttaa gaaaaagaca aaaatgatta atcgcttttt
    22021 tctgttgttt cagttccata ataactatga tcttctaggt ctaaagcatt caaaataagc
    22081 gaagccgttt cttcaataga taaagatgcc acattgatca ctacacatcc tagtttttca
    22141 taaagatcat tcgcaaaatc gagttcagct ctaatttttt cgatatcgga ataagcagta
    22201 tcagggttta atccgtaaga gcgcatccgt tctttacgga tattatttaa aatatctggg
    22261 ttattcgtta gtcccacgat ttttttagga tcgatctccc aaagctgttt gggaatatgt
    22321 gcttgtggga tcaaaggtaa attggcaact tttaaatttt tgttagctaa aaacaagctc
    22381 aaaggcgttt tggaagttcg ggatacgcct agcaaaacga catctgcttc taaaaaacca
    22441 cgaggatctt tcccatcatc gtattttaca gcaaattcca ttgctttgat ccgtttgaaa
    22501 tagttctcat tcaataaatg gagggcacca ggttgccgaa ttggcttgat accggttaaa
    22561 cgttcaattt ctgatatcgg tggcgtcatc acatcaaaac taaataattg atgttcttca
    22621 caaaaagaac gtgttatctc gatcagttct tgattgatta atgtatgcag gacaagtgct
    22681 ttttcttcta atgcatcttg caatgcctgc tttaatgttt tttcatctgt cacgaacgtt
    22741 ctgcggaata ggttgaactc aacggtagga tactgagcca tagtagcttg cgctagtttt
    22801 gtcgcagttt ctccagcaga gtcggagatg acaaaaaaag taacgatttc tgtagaatcg
    22861 gaagacatgg ataaaacctc acttgcattt tttttatgtt tattatacca tactctagaa
    22921 tgcgtacttc gtaatcattt tgatttggag gaataagtca tgaaaaaaca gacattgatc
    22981 gaacaatcat tagaaacatt gaaaaataac ggttttaaat atactaaaaa aagagaagca
    23041 ttgttaactt atttagtgaa gcgtaaccgc tacgtatctg ctaaagaagt ttttgactat
    23101 atgaatcagg aattcaaagg ggtaagttat gatacgattt atcggaatct ccatgatttt
    23161 gcagagatcg atttactgga agaaaccgat ttaaatggag aaatgaagtt tcgttttcat
    23221 tgctgtcagg gggaaatcgg ccatcaccat cattttatct gtacagtgtg cggaacaacg
    23281 aaagaaatcc atatgtgtcc gatgaattat ttcgaagaac agctaggtgg atgcacgatc
    23341 gaagggcata gattcgagat tttcggaaga tgtgaaaatt gtcaataagg gtttaaataa
    23401 aataacattt gataatttta aaaaaaagca agatttcctt gacggtcaaa acagcattag
    23461 atataatatt tacaggacag tcttgttttt tgagatatat ttcaataaca attacggtta
    23521 ctttttaagc tcggagggag ggaattaaca tgtcaaaaac agtcgttcgc aaaaacgaat
    23581 cacttgacga tgctcttcgt cgcttcaaac gttccgtgtc aaaagcgggt actttacaag
    23641 aatctcgtaa acgtgaattc tacgaaaaac caagtgtaag acgcaagaaa aaatctgaag
    23701 cagctagaaa acgcaaaaaa ttctagttct gtgatgaatt ggagttggta gtgtgtcact
    23761 actaagtaga ttaaacgatg acatgaaagc agcgatgaaa gcgaaagata aggaatcttt
    23821 acaagtcatc cgaatgatca agtcatctat acaaaacgag cagattaaag aaggtcacga
    23881 cttgacagaa gaagaagaac taacggtgtt gtctcgcgaa atgaaacagc gacgtgattc
    23941 tttgcatgag tttgaagaag caggacgtga cgatttagct gaaaaagtaa aaagtgaaat
    24001 tgtaatagtc gaaaaatata tgccggaaca actttccgat gaagaaattc gacaacttgt
    24061 tcaagaagca atcactcaaa ctggtgcttc atcaatgaaa gaatttggca aagttatggg
    24121 tgcaattatg cctaaagtca aaggaaaagc agatggaaac caagtgaatg cgattgtgaa
    24181 agaactatta caatcttaat tttatcattt aaactgcgga cagtgattgt ccgcagtttt
    24241 ttgtgttcgt aaaaaaagaa ctaaaaa
//
LOCUS       DAZKPE010000042        23710 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000042 DAZKPE010000000
VERSION     DAZKPE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.042"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            111..1253
                     /locus_tag="ACG930_001819"
     CDS             111..1253
                     /locus_tag="ACG930_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0518977.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            1246..1452
                     /locus_tag="ACG930_001820"
     CDS             1246..1452
                     /locus_tag="ACG930_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFQ0518978.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            1531..2724
                     /locus_tag="ACG930_001821"
     CDS             1531..2724
                     /locus_tag="ACG930_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0518979.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            2929..4068
                     /locus_tag="ACG930_001822"
     CDS             2929..4068
                     /locus_tag="ACG930_001822"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFQ0518980.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            4061..4861
                     /locus_tag="ACG930_001823"
     CDS             4061..4861
                     /locus_tag="ACG930_001823"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0518981.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            4861..5688
                     /locus_tag="ACG930_001824"
     CDS             4861..5688
                     /locus_tag="ACG930_001824"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0518982.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            5693..6400
                     /locus_tag="ACG930_001825"
     CDS             5693..6400
                     /locus_tag="ACG930_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0518983.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            6500..7366
                     /gene="rfbA"
                     /locus_tag="ACG930_001826"
     CDS             6500..7366
                     /gene="rfbA"
                     /locus_tag="ACG930_001826"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFQ0518984.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            7380..7952
                     /gene="rfbC"
                     /locus_tag="ACG930_001827"
     CDS             7380..7952
                     /gene="rfbC"
                     /locus_tag="ACG930_001827"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFQ0518985.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            7974..9002
                     /gene="rfbB"
                     /locus_tag="ACG930_001828"
     CDS             7974..9002
                     /gene="rfbB"
                     /locus_tag="ACG930_001828"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFQ0518986.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            9100..9951
                     /gene="rfbD"
                     /locus_tag="ACG930_001829"
     CDS             9100..9951
                     /gene="rfbD"
                     /locus_tag="ACG930_001829"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFQ0518987.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            9985..12018
                     /locus_tag="ACG930_001830"
     CDS             9985..12018
                     /locus_tag="ACG930_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0518988.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            12062..13342
                     /locus_tag="ACG930_001831"
     CDS             12062..13342
                     /locus_tag="ACG930_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFQ0518989.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            13552..14358
                     /locus_tag="ACG930_001832"
     CDS             13552..14358
                     /locus_tag="ACG930_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0518990.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            14370..15590
                     /locus_tag="ACG930_001833"
     CDS             14370..15590
                     /locus_tag="ACG930_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0518991.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            15580..17166
                     /locus_tag="ACG930_001834"
     CDS             15580..17166
                     /locus_tag="ACG930_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0518992.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            17205..19343
                     /locus_tag="ACG930_001835"
     CDS             17205..19343
                     /locus_tag="ACG930_001835"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0518993.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(19711..20694)
                     /locus_tag="ACG930_001836"
     CDS             complement(19711..20694)
                     /locus_tag="ACG930_001836"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0518994.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            21072..22463
                     /locus_tag="ACG930_001837"
     CDS             21072..22463
                     /locus_tag="ACG930_001837"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0518995.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            22479..23519
                     /locus_tag="ACG930_001838"
     CDS             22479..23519
                     /locus_tag="ACG930_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0518996.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            23538..>23710
                     /locus_tag="ACG930_001839"
     CDS             23538..>23710
                     /locus_tag="ACG930_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFQ0518997.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGR"
BASE COUNT         7685 a         3984 c         4928 g         7113 t
ORIGIN      
        1 ccccaaacct gtgagtagta atgagaggtt ttaagaagat agtacatatc acactttttg
       61 aaaggtggtt tacaggtatt tcaaggctat tgtgggattg gaggaataca atgaacaatt
      121 tagaatttgc acttgaaatg aagaacaaac gtcttgccag cggtctttca caaggagaac
      181 ttgcaagtct tacccatgta tcaagatata gtatcaaccg ctttgagaac ggaaaagcta
      241 acgccagcaa ggaaacacag aacattatcc tgcgttgtct gaattactat atctgcgata
      301 agccttttta tctgctcgtt gattatctgt ctgtccgttt tccaacgact gacgcattgg
      361 aagttatccg aaaggtgctt ggcatgaaag cagattattt tatccattat gactatgggt
      421 attatggcta taaggagcat tatgcttacg gggaaatcaa ggtcatggct tctgatgatg
      481 aacacatggg cgtattttta gaattaaaag gggcaggctc acgcaacatg gaatatgtct
      541 tacaggcaca gaacagggac tggtattcat tcttaaaccg ctgtcttgac tgtggcggtg
      601 ttatccgacg ttttgacttg gcaatcaatg atatgtgcgg tctgctggat attcctgtgc
      661 tatctgaaaa atacagaaat ggtggtgcgg aatgtcgctg taaaaactat gaaaatgtac
      721 aaggtggaaa attaagcgga aaaaaccgta atttagcaag taccctttat atcggctcaa
      781 aggcaagcac aaaatatttc tgcctgtatg aaaaacaaaa ggaacaggca acgaaaaaga
      841 aacataccga tattatcaac cgttttgaaa ttcgtctgcg tgacaaaaag gcggtacagg
      901 cagttgaaga actgttattg acgtataacc ctcatgggct ggtgttttat ctcattaccg
      961 attttgtgga atttcctgac tatccattgt gggagatatt catttcccat gacagtttac
     1021 cttttgaaat gaaccctgta cctgtcaata tggaacgcac tctgcaatgg ctggaaagac
     1081 aggtcatgcc gtcaatcgtg atgatagagg aaatcgacag gctgacaggt tcaaactaca
     1141 tgaaaatgat tgatgaatgt acccaccttt ctgaaaaaca ggaaatgctt gtggaacaga
     1201 tgtgtacgga catatcagac gtaatcgaaa gtgagggggt gttttatgag taatacacag
     1261 gatattcccg tatgggaaaa atacaccctt accattgaag aagcgtcaaa gtatttccgc
     1321 attggagaaa acaagttaag acgattggca gaggaaaaca aggacgctgg ctggctcatt
     1381 atgaatggca accgcataca gattaaacgc cgacagtttg aaaaggttat tgataaattg
     1441 gacgcaatct aatgcaaatg agccttgtat gtgttatgat gaacacaagt catatcaagg
     1501 ctctttccaa caaggaaagg agcagacacc atgaaagaaa aaagacggga taacaaaggt
     1561 cgtatcctgc atactggaga gagccaacga acagacggaa aatacttata taaatatgta
     1621 gacgcattgg gaaacacaaa atatgtgtat gcttggagat tgacacccac agacccgaca
     1681 ccaaagggaa aacgggaaaa accctcactt cgagaactgg aacagcagat aagacgggat
     1741 attgaggacg gtatcgacag cacaggcaag aaaatgacgc tttgccaact ctatgccaaa
     1801 cagaacgcac agaggacaaa tgtgaagaaa agcacacaga aacaacggga acaactcatg
     1861 cggttattaa aagaggacaa gttaggtgct aggagcattg atacgataaa accctctgac
     1921 gctaaagaat gggcgttacg catgaaagac aaaggctttt cctacaatac cattaacaac
     1981 cataaacgct cgttaaaagc gtcattctac atagccatac aagatgatta tgtgaggaaa
     2041 aacccttttg atttcaagct aagtgaagtc atagaaaatg ataccaaaga gaaagtcgca
     2101 ttgacagagg aacaggagca agccttattg tcatttatta agacggacaa cgtgtatcac
     2161 aagcattatg atgatgtgct gatactgtta aagacaggac ttcgtatctc ggaactgtgc
     2221 ggactgacag tagccgacat tgatttcaag aatgaagttg tgattatcga ccaccagtta
     2281 ctaaagagta aggaacaggg ctattatatt gaaacgccta agacgaaaag cgggataagg
     2341 caagtgccat taagcaaaga aacgatacag gcatttcaac gggttatcaa cagccgacca
     2401 aagataaagt cgatagaggt agacggacac agcggttttg tgtttatcaa tccgaaaggt
     2461 aatccaaaag ttgccattga ttataacgcc ttatttatcc gtatggtaaa gaaatacaac
     2521 aagcaccaca aggacaatcc cttgccacat attacaccgc atacgctacg ccatacattc
     2581 tgcacaaggc tggcaagcaa gaacatgaac ccgaaagatt tacagtatat catggggcat
     2641 tcaaacatca gtatcacaat gaactggtac gctcatgcgt ccatagatac cgcaaaatca
     2701 gaggttcagc gtctaatcgc atagaagtat ttaccacgat tttaaccacg attgacaggg
     2761 aaaatataag aagatagacc tagatatgcg aggtttacca caaaagcaaa atgcccgtag
     2821 agccgataaa ataaggcttt gcggacattt gagaagatat aaaaagatag tcaaaaagac
     2881 atatataatt tataataatt atgactctta attaaagtag gtgcccatat gcttgtttct
     2941 tttagtatgg ttataagatt ttttctgaca attttattat cactgatatt aacacctgta
     3001 ttcaaaatca tttcagtaca aacaggtatg gtcgacaaac caaatgaaag aagaataaat
     3061 aaagttccaa tgccttcagc gggcggactg cctatcttta tttcatttgt tatatcgact
     3121 ttattcttat tccgtaaaat tatccctcaa tcgtatattg taccgatctt gattgcttct
     3181 ttagtaatca tagtcacagg agtgctcgat gataaatatg agctgacacc taaacaaaaa
     3241 agtataggga tcttgattgc ttctcttatt atttattttg tagcagatat acgtattgat
     3301 tccttcacgc ttccttttat tggatatatc caactaggct ggcttagttt tcccgtaacg
     3361 attttttgga tcttcggtat cacgaatgcg gtcaatctga ttgacggttt ggatgggctg
     3421 gcggcaggga tttcattgat cggtttaatt acgataggaa tcattggata ttttttcctc
     3481 catgcttcta cagtgtatat tccagttgtt attttctgtc ttgtagcaag tattatcggt
     3541 ttttttcctt acaattttta tccggcaaag atttatttag gcgatacagg agctctattc
     3601 ctagggttta tgatggccgt cctttcacta caagggctga agaacgtgac ttttgtttca
     3661 tcgatttctt tgctgatcgt catgggagtg ccggtaacag acacgttttt tgctatcatt
     3721 aggagaaaag caaaccgtgt ttctttttct acagcagata aaaaacatct tcatcaccga
     3781 ctaatcagtt taggctttac tcataaaggt gctgtcctga cgatttatgc gatggctttg
     3841 atgttttctt tcacagctat ggtcatgaat tatactggaa gaatcggaac gatcatattg
     3901 attattgcca tgttgtttgc tgcaatttta ttatttgaat tgattggtct gatcaatgag
     3961 aaacatcagt ttattttaaa aacattgcga tttttaggga ataaagagta ccgtacgcaa
     4021 gtaaaacaga aatatttgaa gaaatggaac cgtcatatag atgaataaca aattaaacca
     4081 gccgatcctt attagtattg tgacggcaaa cagtgataaa atttttcgga cactagataa
     4141 ttttatttca actgtaaaag atgaaacagc agtaaaaatc cgaatttttg acaacaattc
     4201 acttcccgag tacaaaaaaa gactaacaga gtataggaaa tatccctaca tcgatatcta
     4261 ttttcatgat gaaaattccg gatttggtta tggacataat cacaatctga tagctagcga
     4321 ttctcgctat ggcattattt gtaacccaga tattttagtg gatgaagaga cagttacagc
     4381 attggtcttg ttattgaaag aacatccgga atgtgcgatg ttagcaccta agattcttaa
     4441 tgaagatgga acaactcagc acctcatccg tgagcagctg gctgtttttg attacgtttt
     4501 gcgctttgtg cctttcaaat gggtcaaaaa aaagtttgac aaacgactgg ctgtgtttga
     4561 atgccgagga ttgcctactg atgctaatag ttatgtacgg atgatctcag gtagttttat
     4621 ggtagctgat attgataaat ttaaagagat aaaggggttt gatgagcgtt tcttcatgta
     4681 ctttgaagac aacgacttgt gtttgagttt tgaaaaagca ggttacaagt tattgtacac
     4741 acccttttat gcagttatcc atttttacgg gaagggtgcg catcgaaatg caaaactgtt
     4801 tcgcgtgttt ttgacttcta tgatgaaatt tttcaataag tgggggtggc gttttttctg
     4861 atgaaaccag aaatattagt agtcgttgtg ctttatcagc aactattcag tcaatctcca
     4921 gcttatggac cattaagcaa agcacttagc gaaaagcaaa ttcagcttat tatttacgat
     4981 aatagtcctc aaaggcagca aaatgagctg tttgaaaaag aaaatatcgt ttatcatcat
     5041 gatccgcaaa atcctggttt agcggtggct tataattttg cgttgtctca agcagatgaa
     5101 ggaacacgtt gtctcgtcac tctggatcag gatacgaggc tagtcgacga ttattttgaa
     5161 ctattgcgta aagtaacctt tacagatgaa tgtgttgctg cagttccgat gattttttct
     5221 gggagccgac aagtttctcc cctatattca gatcgttata tcaatcgtac agctcaagca
     5281 gtagaagttg aaggcccaac agctgaacga atcatggcaa tcaattcagg tgttgcctgg
     5341 tctgtcaaat ttctaaaaaa gattggcggg tttaatcctg ctttttcttt agattttttg
     5401 gatcattggc tgttttggaa agtggatcag ttggaaaaaa ctgtggagat ccttcctgta
     5461 cgaatggaac atgatctttc ggttttagac tatgaaaaag tttcaagtaa tcgataccgt
     5521 tctattttac aagcagaaaa tcgattttat catgaatatg atcaaaggca tttatccagt
     5581 caccgacgac aattattgtt aagaacagct aaacagttct tgaccgtcaa aaaccggcat
     5641 atctggcgga tgactttgcg ctcatatgtt aagaattgga aggtgtgaat tcgtgcgttc
     5701 ggtttgtata gctaccttta atggaggcag atatttaaga gagcagttag atagtatttt
     5761 atctcagctt tcagcagaag atgaagtagt catttctgat gatgggtcag tagatgatac
     5821 atgggatata ttaactgaat acgcagaaaa agataagcga atccagcttt tttcggggcc
     5881 tcgtcaagga ttgatcgcta attttggtta tgcgatccag cagacgaaag gagatctaat
     5941 ctttttggca gaccaagatg atgtttggtt ggagacaaaa gtgaaaaaga tcactgacta
     6001 ttttgagcag aatccggatc agctagtagt agtttctgat ttaatcattg tggacagcga
     6061 gctgcaagag atccatgatt cgtatttttc gtttcgaaat tccaaagaag gatggcttaa
     6121 taatgtgata agaagtcact atattggtgc tggtatggct ttccggtctt ctttaaaacc
     6181 cgatattttg ccgatcccgt cagaagtgcc gatgcatgat atgtggattg gtttgctggg
     6241 aggaaagaag actgggttcc taagagaacc gttaactctg taccgaagac atgatttaaa
     6301 cgcgagtgag attgaaacac attctaaatt acggcaaaaa atttcttggc gtgttcatct
     6361 gattacggcg ttgatcaaac gaaaatggtt taaacgttga taaaagatgt ttaaatcctt
     6421 aatatttcca tgacaaatat aacaattgat gagataataa caaagtgaaa tttgaaatca
     6481 aaaaggagag cagatatcca tgaagggaat cattcttgct gggggcagcg gaacacgtct
     6541 gtacccttta acaaaggcaa catcgaaaca attgatgccg atttatgaca aaccaatgat
     6601 ttattatcca atgtctactc tgatgttggc gggaatcaaa gaaattctga ttatttcaac
     6661 gccacaagat acaccacgtt tcaaggaatt atttggaaac ggaaatgatt taggactgca
     6721 gatcgaatat gcagtacaag aaagtccaga tggattggca caagcgttta tcattggaga
     6781 agaatttatt ggagatgata gtgtctgctt ggtattaggg gacaatattt actatggtgg
     6841 cggtctgtct aaaatgttgc aacgagcagc ttcaaaagat acaggcgcga cagtatttgg
     6901 ctatcatgtc aatgatccag aacgctttgg tgtagtagaa tttgatgaga atatgcaagc
     6961 tttgtcgatt gaagaaaagc ctgctcagcc aaaatcaaat tacgctgtaa ctggccttta
     7021 tttttatgac aatgaggtaa tttctatcgc taaaggtatc aaaccttcag aacgtggaga
     7081 actagagatt acggatgtca ataaagcata tttggataaa ggaaaactat ccgtagaact
     7141 tatgggacgc ggatttgctt ggcttgatac aggaacacat gaatcattgc ttgaagcatc
     7201 tacctttatc gaaacaattg aaaaacgtca gaacttaaaa gtggcttgtt tggaagaaat
     7261 tgcttaccgt atgggctaca tcgataagga acaattgctg gcccttgcac agccattgaa
     7321 aaaaaatcaa tacggtcaat atttattgaa tttggccgct gaataaggag tccttacaga
     7381 tgaaagtaac agatacaaaa ttaacagatg tcaaaatcgt agaaatggac gtctttggcg
     7441 atcatcgcgg tttcttcaca gaaagttatt caaaagcaaa atttgcagaa catggattga
     7501 aatatgactt tgttcaagac aaccattcac tatcagctga agctggtgtc cttcgggggc
     7561 ttcatttcca aaaaggagaa gctgcacaga caaaattgat tcgggtagtc actggagcag
     7621 ttttagatgt agtagtggat atccgcaaag gtagcccgac ttatggtcaa tgggacggat
     7681 ttatcttatc tgaacataat catcgacagt tgcttgtacc taaaggatat gcccatggat
     7741 tcgttacttt gacaccaaat gtgaacttcc tttataagtg tgataattac tataatgcag
     7801 aagcagatgg gggcatcgca tttgatgatc cagatttagc gattgattgg ccaattgatc
     7861 catcaagagc gattatgtcg gaaaaagatc accgtcatcc gacattaaaa gaatttgaag
     7921 cagaaaatcc atttgtttac ggagaaatct aagaattaag gagaaatttt cttatgaaaa
     7981 acatcattgt taccggaggt gccggattca tcggctctaa tttcgttcat tacgtggtaa
     8041 acaatcatcc agaagtgcat gtcactgttt tggataaact gacttatgca ggaaacaaag
     8101 agaacttggc tggacttcct agcgatcgcg tagaattggt cgtaggagat gttgcagatg
     8161 cagaattagt ggaccgtcta gtaaaagaag cggacgcagt tgttcattac gcggcagaat
     8221 cccataacga taattcatta aaagatcctt tcccatttgt acaaacgaat atcattggta
     8281 cgtatacact tttagaagct tgccgcaagt atgatgtacg ctatcatcac gtatctactg
     8341 acgaggttta cggcgatctt ccattacgtg aagacctgcc aggacatggg gaaggcgaag
     8401 gagaaaaatt cactgcggaa acaccatata atccttcaag tccatattct tctacaaaag
     8461 ctggttcaga tctgttagta aaagcatggg tgcgttcttt tggcttacgt gcaaccattt
     8521 caaactgttc aaacaactat ggtccttatc agcatattga aaaatttatt cctcgccaag
     8581 taacgaatat cttaagcggt attcgtccaa aattatatgg cgaaggaaag aatgttcgtg
     8641 actggatcca tacgaatgat cattcttcag cagtgtggct gattttgacg aaaggcagaa
     8701 ttggcgaaac ctatctgatc ggtgcagacg gtgaagaaga taataagacc gtgatggaat
     8761 tgatcttaga aatgatgggt caaccaaaag atgcgtacga ccatgtaaac gaccgtgcag
     8821 gacacgactt gcgttatgca atcgattcga caaaattacg ggaagagtta ggatggaagc
     8881 ctgagtttac gaacttccgt gatgggttgg ctgacacgat caaatggtac gaagaacatg
     8941 aagactggtg gaaaaaagaa aaagaggccg ttgaagcagc atatgccaaa aatggacaat
     9001 aatacagaga aaatgtcact gtattaatgg aaaaacacat gtgaggcagg cgctcgcctg
     9061 tctctttttt aaaataaaaa tcaaggagcg gataatcata tgtttttatt aactggagga
     9121 aatgggcaac taggtacaga attgcgccat ttattagatg aaaaaaatct gcaatatgtt
     9181 tcaacagatg caaaagactt ggatatcaca gatgccgaga aaacaatggc ttacatcaca
     9241 gaattaaaac ctgatgttat tttccattgt gcagcttaca cagcagtaga taaagcagaa
     9301 gaagaagcaa aagaattaga tgagaagatc aatgttgatg gtacaagaaa tgtagcactt
     9361 gcagcaaaag ctgtgaatgc tcaattcgtc tatatcagta cagactatgt tttcgatgga
     9421 aaaaacaaaa atgtagaata cgaagtagac gaccaaacga atccactaaa tgaatatggt
     9481 cgtacgaaat tattaggcga aaaagcagta gaagagattt tagaagacta ttatatcata
     9541 cgaacttctt gggttttcgg gatctatgga cacaatttcg tcttcacgat gcaacgccta
     9601 gcggaaaccc gcgacaaact gactgtagta aatgaccagt ttgggcgacc aacttggaca
     9661 cgtactttgg cagaatttat ggtatatgtc atcgaagaaa aagcaccatt tggtatttat
     9721 catttgtcga acgaaaatag ctgttcttgg tatgaattcg caaaagaaat attgaaagat
     9781 acagatgtag aagttgcacc tgttacgtca gaagaatttc cgcaaaaagc aacacgtccg
     9841 cagtattcag tcatgagcct gaaaaagaca gaagagttag gatttgtcat accaacttgg
     9901 caagaagcac ttgcgcaaat gctggaagct gccaaaaaaa tgaataagta atttcctttt
     9961 atcaaataga atttggagca tgatatggaa aaacaaacaa gaagtgcacg acgaaaagaa
    10021 aagccaaaag cgaaccaggc agattcgaat ttggtgcttg acctgtttct aaaactccgc
    10081 tatcttattg gcgttttagt catcgtggtc atcgttactt ttaatttaaa cggaagttca
    10141 cttggtgttt gggataaata tgtgtcgcaa agagacgatg ggaaaaaaac tgatgtgatt
    10201 tttggacaga atcgggaagt gcggtcagac gaatggctgg tgcagacacc tttttacctc
    10261 tcacaagctg aagaggactt tccgttggtg aacgaggatt attcattaaa cggacaaaac
    10321 atgatcattg cgtataattc tcctgtaaag gatattacgg ttatcggaaa accattcaac
    10381 tggggattct ttttcctcgg aagagatcga ggactttcct tttattgggc gatgaaatta
    10441 gtcgtcatgg tcttgcttgg attcgaagta ctgatgatat taacgaagag aaaaaaagct
    10501 ctatcgctaa tcggtgcatt tgcgctgaca ttttctccag cagtccagtg gtggttcatg
    10561 caacatgtgg gcgatttgat tttctttact ttgggactga tgactgcttt ttatcattat
    10621 ttctacaatc atgataaaaa atggctacga acgttgatga tgcttttggt ggttattttc
    10681 ggtattgggt ttattttagt gatttaccca gcccatcaag tgatgctggc gtacttgctg
    10741 attttttatt ttgttggcct gcttatttac tatagcaaga aagtttcatg ggatctgttg
    10801 gatgtagtgt tgattggagg ggcagtttta tttattggcg gagtcatggt tcatttctgg
    10861 ctaacgtcaa aagacgcatt gttagcttct ttgaatacct tatatccagg aaaacgggta
    10921 agtactggag gaaagtggac gattggcgaa tttttttctt tccttacaaa ttggaaaatt
    10981 ccttttgaag atatcaacta ttcgaataac tctgaagtgg ccctgttcta tcactttttt
    11041 ccaactgtat tcctagcaag tccatttgtg ttatttggca aaaaagatag cgaacaaaag
    11101 ttactgggac gtattttgat gattttttgt ctgttttcta tcttttggat taccgttggg
    11161 ttgccaaaat ggctagcaga aatcactctg ctgtcttatg ttcctccatt aagagccatc
    11221 cttactttta gttttgcggc ttgtttatta tcgatctggt ttatcgctta tatttggaga
    11281 gaagatgtta ttcctatttg gtataaattc attttgttgg cagtaaatgc atggtcttat
    11341 ttctatgcga ttacgcattc gaaaatggat aattattttt cggattttga aaccatcgca
    11401 gttgctgtgt tgggaacagt gattttagct tttgcattat ttggctggag acgcttgttt
    11461 tacctcgctt ttgccgcctt agttatcgta tctggctttt tcgtcaatcc agtcgtagaa
    11521 ggtacaggag cgatttttga aaaaacactg gcaaaagaaa tccaaaaaat cgatcaacaa
    11581 gatcctggta aagtttggtt gtctgaagat gaattatata acttcacccc aacattggga
    11641 gtgaaatcct tcaatacagt acgcttttat ccagatatag ctgcatggaa gaaaatcgat
    11701 ccgaaagaag aatacgagaa gtattataat cggtatgctc atacaagagc ttttatcgct
    11761 aaggaagata caaagttcat tttagatcgt ccagatatgt tttcggtcac gttgaatttt
    11821 gaagacgcag aaaaattagg gatcgactat gtgatcagta aacgaccatt aactgattac
    11881 aaccaattat atgaagcgca gttcacgcag ctatatggac cggataaaga cggttatatg
    11941 atttttaaag tagaatatcc ggattatcca gatgtaccac aaacacaaac tcaggaaaat
    12001 cagctagtcg tacagtaata ggctagctga gaataatcct gaaatgttag tagaaaggag
    12061 agtggagata attcaagcaa tcgtacaaaa atttgtcaac aaaatgagtg tcggtttctt
    12121 gcttttgtta ctgacgctag tcttttttgt ttggacagca gggttaggtt ttccagcaac
    12181 tttgtttata tataacaata gttcattact tatcgctttt agtgtggcta ttttgctcat
    12241 tttaaatgtt tataaagcaa aaggcgtcga ttttctttat ctaggtgttg cgcttgccct
    12301 tttcattttc ttttcttact ttcgggaatt aagaaatgag tctttatttg gagacttact
    12361 gtttcctttg attattttat tttgtttagt aattaaatgg atcgagtgga caaaatggga
    12421 tcgcggtatt tatctgattg tcttttcggt cttcctcgga atcacgttat atcgtgtatt
    12481 tacagagatc caagtaccag aaggacaaag catctgggct ccaggcaatt cgctttctga
    12541 tatttggatc aatacgaata taatcggaag ttctttgatg actcttgctt tattgatcag
    12601 tggatttgcc agttcttttg aacgatggta tgtacgaatc atcggtgcag tagcagttgt
    12661 tgcagctttt ctcgggattt gggtctgcca atctagaggt gcattagtcg cgttgattgt
    12721 ttttgcgata ttggatcttt tacctaaatc gttgatgcgt gtcattcgtg cgccatttat
    12781 tgcttacacg gttacgattc ttttagcttt gccgatttct tatctggcgg ctgtctctga
    12841 aaaagtcaat ttgtttaccg gtcgagaaga tatttggcat aaattctatc agacgctagg
    12901 agaaaaatct gaacaaattt tactaggaat gaaaacattt atcttccaac gaggaaacca
    12961 atttttagga aaccacaata gttataattc tattttgaat atctatggat tgataggatt
    13021 tgggattgct gctttgctgc ttatcctttt tattggtcgc ttaacgttga aagcagattt
    13081 atccaacggg cagatgactt ttatctgggc cttttttgcg gtgatgatgc agtcatttat
    13141 ggaggataca ttgacttcat acccatgggt tccgattatt tatatcctgt tggctatggc
    13201 cgttcatcga tatgatgaac cagaagttgc ggaggaattc tatgttatgg aagaggcata
    13261 tgacgatatg acttatgatg atacatctta tgaggaacaa ccagatagcg ctcattcttc
    13321 caggatccaa cgctatcatt gataggcaca aaatacgaga gaggctgtga caaccgtcgc
    13381 agcctttttt ggtttattgc aattgtctag catcttctgt aaaatagaaa cgttagagaa
    13441 aatcttgtat catagaaaat taagaaagaa ataagaacgc agctcggtac caaaaatatg
    13501 gtaaaatggc acttgactgt aattcactga aaatcgcttg gaggaacaca aatgtttaaa
    13561 gatttgtatt tatttatgaa ggacatttat cagaacagaa aattattgct acagttttcg
    13621 atcaatgact tcaaatcaag atatgcagga tcgtttttag gaatcttatg ggcgtttatc
    13681 aatccgctat ttactgtatt gatttattgg ctggtatttg gtgttggact gaaagcacaa
    13741 atgatcgatg caaaataccc atttatcgta tatttagtta ccgggatgat tccctggttc
    13801 ttcttctcag atgcatttgc atcaactacg gttgtttttc gggaatatac ttatttagta
    13861 aagaaagtcg tattcaatat tcgtatcttg cccacgacga aaatcctatc caatctgtac
    13921 acccatttat tcttcattct gattggcata gctgtcgcgc ttataaatgg tatatatcct
    13981 tcagcaatgt ctttacagct gatttattat ttattttgca tgtgtgcttt cttgacagga
    14041 ttgacttggc tgacggcatc gatccaacca tttttacctg atatcatgca attaattacg
    14101 atcgtgctgc agttgatcat gtggacatta ccgatattat ggagccctaa tcagtttgat
    14161 tcaggtcttg taagcatatt gaaattaaat ccgctgtact atgttgttca aggttatcgt
    14221 gagtcatttt taagtgaagc ttggttctgg gagcatggaa catatacttt gtatttctgg
    14281 gttttcacgt tagtaatgtt cgtaatcggc tctgcagtgt tccgtagatt gaaaccacat
    14341 ttttcagatg tgctgtaagg agaatagcta tgacagaata tgcaattaga ctaaaagata
    14401 tcacaaaatc ttataatatg tacgcaaaac cttcggatcg atttcgtgaa gccctcaatc
    14461 cttttaagaa atcctatcat gatgtatttt atgcgttgaa aaacgtgaat gtagaaataa
    14521 aaaaaggtga gatgatcggt ttcgtgggag aaaacggatc gggaaaatct acaatgttga
    14581 aaatcattac gggagtactg acaccaacat ccggcacgat ggaaatcgaa ggaaaaatct
    14641 cagctttgct agaactagga tcaggattca atcctgagta ttctggctat gaaaatatct
    14701 atttaaatgg aatggttcta ggattttcaa gagaagaagt cgatgaaatg gtcgatgata
    14761 tcattgaatt tgctgacatc ggagaccata tttatcaacc tgtaaaaact tattcaagcg
    14821 ggatgttcgt tcgtctagct tttgctgtag caatcaatgt gaatcccgat attttgattg
    14881 tggatgaagc attggcagta ggcgatcttg aatttcaact aaaatgtatg gaaaaattta
    14941 cagaaatcaa gaactcggga aagacgattt tattcgtttc tcatgatatc agttcgattc
    15001 gtcgtttttg tgatcgttcc tattggttga aaaacggaga agtcgtcgaa tatggcgata
    15061 cgatggaagt aacgacgaat tatgaaaact ttttaaagaa aaaatcagtt aaaacagtgg
    15121 atcggaataa aaaccaagta gaacggttcg ccgctccaga tatcgtcgac gtgacgaaag
    15181 cggaattgtt ggataaagac aaaaatccgg tggatatgct ggaacaagga gaaaaactat
    15241 acgttaaagt aacttatgaa gtaaaagatg atacaatcaa aaatccggtt ttaggaattg
    15301 cgctacgaac agtcgacaat ttttatgtat gcggacttaa tactctacta gatggtatca
    15361 agattccttg gaaaaaagga gagaatatct tttatctgga gtatgaaaag ttaggtttgt
    15421 tagctggtga atattatttt gacgttgcgg tctttgaaga aaatgcaacg gttcctttgg
    15481 tatataagac aaagtacatg aacttgtttg tcagcggttc ttatatcgga gaaggcatcg
    15541 tggtcttaga ccataaatgg gaagaaggga ctcatagcaa tgaaatatga ttttgaaatg
    15601 gacctagatg aacaaagcag tgtgggaaaa attgccgcac agatcaaacc aggaagtaaa
    15661 gttttagagt ttggtcccgg aaacggccga ttaacgaaac atttaatcgg agcaaaacaa
    15721 tgtgaagtga gcattgttga gttagataag gaattgttcg attttgtcag cgaatttgct
    15781 caagatggat tttatggtga tatcgaaagt tttgagtggg caaactatta tgctggacag
    15841 acatttgatt acgtcttgtt tgcggatgtt ttagaacatt tggtagatcc tggaaaaaca
    15901 ttgaagaaag tcagagaatt tttgaatgaa gaaggagaga tcctgattac attccctaac
    15961 ttggcgcata attctgtcat gatcgatttg ttcaataacc aattgccgtg ggcttcttat
    16021 ggtctcctag atgaaaccca taattctttt tatactcatg atggcttcca aaaagttttt
    16081 gaaaaagcgg gattattcat taatattgaa gattatttgt acttagctgt aggtgataca
    16141 gaattaaaat caacttatga agaattgccg gaagctgtac gctatgattt caaaatgcga
    16201 ccatttggtg aagtctacca atactttttc tcattgatga aacatccagt agcacaaagt
    16261 tccattgcag agccacaaaa ttctaattat gtaaaagtgt tagaagtaac ccagcaaacg
    16321 aaacaagatg aaacaatcca acaaatacca ttcaataatt tcacagggga aaatgagaca
    16381 ctaagtttcc ccgtatcaga aacaacagaa agaatggtgt ttcgcttcgc gcaacaacct
    16441 agctttatcg aattcagcgc agaagctgcc ggagaaaaac taacatttat cgattcgaat
    16501 gctgtagtca aaacagtaaa tgattgttat ttgtttgatg ggaaagaatt accagagttc
    16561 gttctaacgg atatttctgg gaaagaagtg actatccatt gtcactatcg ctttatcggg
    16621 gaattgacac caacaatgaa agaattgttg gaaacgattc gtcccatggc tgaagtcaca
    16681 aagcagcttt ctgagaaaaa tgacgaatta gaaagagaaa atcatcatct tcttgaggaa
    16741 aatacaagac tagaccatac gttaaaaaca accacaaatc gctattgcac attgttggaa
    16801 agtgatgaat ggacaataaa acatagacta ggacgacgta agaaagaaac ttcgaaaaaa
    16861 atccaagaaa aagaactttc tatatgtatt gacgagaaaa tctgggatgc agaaacaaaa
    16921 atattaaaaa tcatcggatg gggaatcgct aattcggatc gccagccctt gtcctataag
    16981 ttatcagctg accaatcgcc atttttcgaa gcaattcctg tttcacgaga agaagtcaat
    17041 caagcagaac agctcgcaaa aggaacagaa gcgggatttg agttacgaat cctttgcgag
    17101 caagaacgtt cattcttagt ggaagcagta gctcaaaatg gccaatcatg gatcattgaa
    17161 atgtaaataa tgattaactt ataaagataa ggagtaaacg aatcgtgcaa aaaaaagaaa
    17221 ttgccgtatt tatcgatcaa atcactcgtg aacgggccac tggcgatttg cttattgtgg
    17281 gctgggcaat tgatgaagtg accaaagaaa tccctacgat aaaggtagaa aaagaaaatg
    17341 tgattgctga agcaacacat gtcgtaagat tggatatcaa tcatttatat aatcttgatg
    17401 ttaagaccca aagcggtttt aaggtacgtt tatcagggaa aatgagagga aaagccatct
    17461 tagacttcca aacagcgaga catcaaaatg gcatagctgt gaaattaaac ggtaaatacc
    17521 cttatgatga cggcattgaa tcttcatggg aaagaaaaaa aagattactg aaaaaaggga
    17581 taaattatgc aaggactcat ggcgtaaaaa aagcgatccg tcgggtcaaa ttggaattga
    17641 agccaggatc gatcgactat gcagagtgga tcagtcgtca tgagaaacca gatttgaaag
    17701 agcaaaggaa agaagcacaa ggatttgcgt accgtccatt gatttccata cttatgcctg
    17761 tctataacgt tgaaatcaaa tggctcgaaa aatgcattga ttcggtactg gatcaaacgt
    17821 atgatcattg ggaactatgt atcagtgatg atgcttctac tgatccagct atccgaaagt
    17881 gtctggaatc ctatcaagca aaagatgata gaatcaaagt cgttttccga aaagaaaatg
    17941 gacacatcag tctggcaact aattctgcat tggaaatagc agaaggagaa tttatagcac
    18001 tcttagataa tgatgatgaa ttaccgccat ttgcattata tgaagtggca aaagtgctaa
    18061 acgtacatcc agaactggat gtgatctaca gtgacgaaga taaaatcgat gcagatggca
    18121 atcgctttga tccgcatttc aaagcagact ggtcgcctga tacattgatg ggaaataatt
    18181 atatctctca cttaggcgta tatcgaacaa gcattgttaa agaacttggc ggtttccgta
    18241 aaggctatga aggttctcaa gattatgatt tggtccttcg tgtgacagaa caaatccctg
    18301 cagatcatat ttaccacatt gaccgagtct tgtatcattg gcggacgatc ccaggatcaa
    18361 ctgcaagtaa tggcgaagcc aaaagttata tctatgattc cggagtgaaa gcattgacag
    18421 atgccctgtc tagaagaaac atcaaaggaa gcgtacgtcc tggcagaatt tctggatttt
    18481 atgagattgc ttatgacgtc ttgcaagagg atttggtcag tgtgatcatt ccaacgaaga
    18541 atggctatga agatctaaaa acttgtgtgg attcgatcat cgaaaaaacg tcttattcaa
    18601 attatgaaat cattattgcg gataacggaa gtacagatcc aaaaatgcaa gaattatttg
    18661 cagaatacaa gcatcagctg aaagaccgct ttatcgtaga attgattgac attccattca
    18721 attattctcg aattaacaat ttagcagcag aaaaagcaaa cggcaaatac tttttattct
    18781 tgaataacga tacagaagtg attgagccag attggatgac ggtgatggtt tcttatgcac
    18841 agtttgatcg aatcggctgt gtaggagcaa aactgtttta tccagatgat acaacgcagc
    18901 atgcaggagt attattagga atcggtggtg ttgcagggca tgcattgaat aactatgatc
    18961 gaacacattg tggttatttc ggccgattgg tcattgacgt caattactta gcagtcactg
    19021 cagcttgtat gatggtcaag gcagctgact tcaatgctgt taacgggttt gatgaaacat
    19081 tagaagtagc attcaacgat gttgacttgt gcttgaaagt ttatgaactg ggtcgttaca
    19141 atgtctatgc acatcaagca gaattgtacc atttcgaatc taaatcaaga ggttatgaag
    19201 atactccaga aaaacaaaga cgttttgctg gtgaaatcaa aaaaatgcaa gataaatggc
    19261 cagcatatat tgcgcatgat ccattttaca atgataattt aacaaaagaa ggaatcggcg
    19321 acttttcgtt gagaccagat taaactataa taaaaagctg ttatgttgtg attcgctcgc
    19381 acataacggc tttttatagt tttttgtcaa aaaaaggcag aaggtgccga ctcaaaaaaa
    19441 taagtcgagg ttgggacaga agtgtttaac tccgagaaat aagaagaaat tcacgaaaat
    19501 tgcttttcaa atttttgtga atttcggctt atttaagaag aagttgcttc tgctcccacc
    19561 gtttattcgt ttttaaagaa tgagacaaaa gtgtttctta cttttgtccc acgctcttat
    19621 tcatgctcag agcgccaata gatacaaaat catagccaaa gtttcacgaa ccctagctgt
    19681 caaagaatcg atattttatt ttaatatagg ctattttaaa ataaatggtt taaggtattc
    19741 ctctacaaaa gccactctat caattatcat gggtttaaaa taagaagtga tggagataac
    19801 cagattgttc ttagcgtcaa tataaagaac atttccacta ttaccaattg ctgaatatat
    19861 ttcgttctca gaatctaata cccaccataa atagccatat ctcatatttt gtaagtcttc
    19921 taaagcactg gttctaggtt tgaacatctc gtttatccac atgggtggta cgatttgttt
    19981 tcctttatac atccctttat ttaggcataa tacaccaatt tttgccagat cacttgccga
    20041 taaacacaaa ccatatcctg ccgtcccgat atttagtgga tcacaaaacc agacattggt
    20101 tttaggagac ttatccattg taaactgctt atgttcttca gctgtttcag cataataatt
    20161 gacatggttt ggtatcccta taggatcaaa tagatactta ttggcaaaat caacagttgt
    20221 tagcttactt gtctgataca acaagccagt taatatgtgt aaacagacag tttgatagtt
    20281 gaattcgccg gttatacctt ttcttcctcc caataaatct agtgatgttt ttgtccaatc
    20341 ttcacttgaa cagacttttg tccatggatc gcctttacat ttgtagggtg ctttcattgt
    20401 tagcaagtgc ttgattgtaa tagcgtaaat agttttctcc ccgcgtttca ctttatactc
    20461 tggaaaataa tctaatactt tatcatcgat acttttgatt aatccttgct ctaaagcaat
    20521 gccaatcagc aaagatacaa tacttttcgt tgctgacatg atatgacaag tatcgtcttt
    20581 tttataacca ttccattcat ctgtataaac ttctacccca tccttatatg cgacaatttg
    20641 acatatattt ggttgtcgaa aaccaataaa atcatgcaac tcttgtttat tcataagata
    20701 ttacctcact ttcttctata agcataatgt cattaaaaat cgatttcaat tttttcgatt
    20761 cttcacgtaa tacaggtatt cttatggact agacagcgct ttgggaagat ggattctctg
    20821 aaaaatataa aggttcactt tatgagtgga taaaaaaagc agcaaatact tcgacttctt
    20881 taatttacca acattagtga aaatcgattc atctggagat ttgtaattta gagtccttgt
    20941 cttgattaga ggtgtataaa gctttttatt agacattttt aaattccatt acaatttgct
    21001 tataaactag gtttttaaag gtgactatgg taagataata gagatattat tttgtgatta
    21061 ggagtgtata tatgaataaa aatggagaat ggagtgctgc acgacggata ttcattatat
    21121 taatggatgt tattgtatac aatgcagcaa tatatagtag tttcttactg aagtttcgtg
    21181 gagagatccc attacgaaat ttagaaactt tccaacactc agcaattatt atttcagtga
    21241 tttttattgc gttgaacatt ttgttgggtg catatgtttt ttataatcga atgatcagtg
    21301 acatcgtgtt tgtcacagtc atcggtcagg tattgatgac actagggatc atggtagtga
    21361 cttttgcggg ccgctggttt gcttttccac gtcttgttat cttactttca tttgttctcg
    21421 gtacgctttt cttaagtatc tatcgtattc tcgtatataa actttattta cgcgtaagtc
    21481 gagataaaaa ggtcgtcatt attgggttag aaaaggatgt cgcaccagca atccaaaatt
    21541 ttggttcaaa gaaaaacaac aaacataaag tcgaagcagt cattcttgat aactattatg
    21601 caaacatcaa aaatatgatt aaagacatcg atattgtcta tcttgcttct catatcgaag
    21661 aaactgaaaa aatcaaaatc tatcaattag ttactaaaaa tgaaaaaaaa ttgtttttga
    21721 atacaacatt tgaaaacttg acattgatca atccaaatat tatgaatttc gaagatgaaa
    21781 gtattattga agcatctgga tttagaatcc aacctgaata tgaactattc aaacgtttgt
    21841 ttgatatcat cgtttcactt gttttattag ttattgcttc accatttatg ttattcacag
    21901 caattttagt caaagtgaca tcaccgggac caatcatcta taaacaagtg cggatcacaa
    21961 aaaatcaaaa ggaattttca atctataaat tccgctcgat gaccgccaca gccgaagcaa
    22021 aatctggacc agttttagct aagagcaatg atgcacgagt aacgcctgta ggtaaattta
    22081 ttcgagctgt ccgctttgat gaattaccac aaatcttcaa tgtgctgaaa ggcgatatgt
    22141 cgatcgtagg accacgtcct gaacgtcctt tcttcgtcga tcagttcaat gcagaaaacc
    22201 cttattacta cttacggcat aatgttcgtg ctggtatcac tgggtatgca caagtctatg
    22261 gaaaatatgt ctctgattac aacagtaaat tacgttttga tttactttat atcaaaaaat
    22321 attcattgat gcttgattta aagatcttgc tgcaaaccat caagatccta tttgataaaa
    22381 tgtcctctca aggacttgaa gaagacgaaa atgtgatctc attggcagaa attgcttttc
    22441 cgaatgaaaa aatctttcgc tagttgggag gcgtaaaaat gaacaatccg aaattcagca
    22501 taatcgtacc agtatacaat gcagaagcaa ctattggtcg aacgattgat attctaaaag
    22561 aattggatta tgaagagtac gaagtcgttt tagtaaatga tggatcaaca gatcaaacac
    22621 aggaaatcat tcaagaactg attgaaaatg atgaacgttt tgaattgatt actacgacca
    22681 atcaagggcc cggattagca agaaacgaag gaataagaca gtcaaaagga gaatatctct
    22741 tattcttcga tgcagatgac acgccagtaa aaacgatctt gtcagattat gatcatttgc
    22801 tagaaaagag tccaaaagcg gatcttgttg ttagttcgtt tgtttttcgt acaatggacg
    22861 agggaagaat cgtttccgaa aaagaaaact tagttacaga atgtcactat ctaactcacg
    22921 aagagtttat aaaagacatg tatcagttaa tgaatgaaca gttgatgtat gttgtatgga
    22981 acaaatgcta tcgtagcgat attctgaaaa ataaccaaat tctatttaaa acttataata
    23041 gttgtgagga tcgaatattt aacttacatt attatgaata ctgtcatcaa gtgatcatga
    23101 acccaaaagt agaatatatt tatgaatttg aaggtgggaa ggggatcact aatcaatacc
    23161 gacctaacaa gttcgaaaca tttaaagaat tctattcatt agcaaatact gtaacagacg
    23221 atattaataa agacggtatg gcggcgcttc ttttaaaagg gacaacttca gttatttttt
    23281 ctatttatag tacctctgca agaacttcaa aagagaagaa agacgaagca aagcagatat
    23341 tgagtgatcc agtgatccga gaagccaagc aaattgctaa gacggattct tcagcaaaaa
    23401 aaataacaaa gttgctttac aatatgccag ctccactatt tttatctgct gtaaaagttg
    23461 gaagcttcgt tgaagtgaaa atgccagggt taatggctgc tttgaagcga gtatattagt
    23521 taatggagga aaatataatg aaaagaattt tgcattttca gggacgaatg ggtttaggtg
    23581 gagcagagtc tttcatgatg aatttatatc gtaaaattga tcgtacaaac tatcaatttg
    23641 attttttgat ttatgaagat tatgcagatg ttcaagacta tcattcagag attgaaagat
    23701 taggaggccg
//
LOCUS       DAZKPE010000043        22711 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000043 DAZKPE010000000
VERSION     DAZKPE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.043"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1805
                     /locus_tag="ACG930_001840"
     CDS             <1..1805
                     /locus_tag="ACG930_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HFQ0518998.1"
                     /translation="AKRKVISKEDERKKITESKAYKDREKNKFEESQRFTDEQEEAYE
                     EAVETVDIDKYKELSNQLLLGTSEFGLPYIINFSEFNQHVLVPATTGSGKTTLLQLLV
                     QHAVKFNFPVILIDGKGARDTLESMREIAKFYDKEVHAFTDDGDMRYNPVEHGNDISI
                     RDKLVSLAETESVFYSGAAKALLQVTIQLLDEFKGAKVTLSGDTRTTETVERSLPFVQ
                     RFLLPRNVLHLFADAILPNNPKLFEIEVEKKIQKPKKKSVKEGSEILPDSDLDKEEKE
                     EDSQIKNSKFRNISQLGIAQKETETIVLNPETLDLDSYYLLLKRNLRYLPTDKETGEN
                     IKQKLFERLFIRYEHKDSPFYLYATSEALQTNINMLLDSELGKLFDTKNAKNVLDVQE
                     IVNQRKLVYVSFNGLIYKEYIRTLAQMLVGDVNYFASEMYRKNVKREVLVIFDEPASY
                     LNETFIDMVNKGRGAGVYGIFTPQTMADIAKLGDKLMEQLVGNVNTLFIGKTNEKGEA
                     EYWSETMGTYQDIDVTSVTEQEDGYSDVGKSDWSGDRGTKRNVDRFKISPNKIKELRT
                     GEFIIYRTAENVNLPPQKVYVRNALNWLKNNSKI"
     gene            2327..3112
                     /locus_tag="ACG930_001841"
     CDS             2327..3112
                     /locus_tag="ACG930_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFQ0518999.1"
                     /translation="MKPLLYNYYIDYTKKDKTRLIILCLLHELRVISVQQLIDFFQIE
                     RLSAESTVYKHLNLLKTDGLIARSKNGMHTFYYLTKEGHNYIGGYYTLPKVPEYNLQH
                     HLQINDYLIKMLELCNKHPHLKAVVSERRKVYEVKDEKKNQKGVKYFVPDFIFMFLDS
                     IGREVEWQFEIELTLKTKRRYSQGVFPKYIKHLKNYEDARLIYVTPSSIIKEELDMFK
                     EYFIDKEGDEYKEVFDRLHVFSAEEFESELKRLLEKDKFINWE"
     gene            3118..3606
                     /locus_tag="ACG930_001842"
     CDS             3118..3606
                     /locus_tag="ACG930_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519000.1"
                     /translation="MRRIEKEFNKKLAGYERELKKLGCLDDETGLIPISKRRWHVIWW
                     QPVTLAKTIVRSYRLTLDNQNLCILGDVEITIYHDGTYGISKEAVPIFINDLLSLKKL
                     ITIFYGTPFNLNFEKIRCVNFNRYCVSIPEIYVEKFEVLINYLIILSSCLHEVKKHVE
                     YD"
     gene            4198..4464
                     /locus_tag="ACG930_001843"
     CDS             4198..4464
                     /locus_tag="ACG930_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519001.1"
                     /translation="MLTTKEKNRFKKMVEGNKTFHYSYVDRLRQDVRYYVNQCESAVK
                     ARESMEILEFIYSLFSDKELPAWYTKADLENDKKSIEKLERWAA"
     gene            4497..4991
                     /locus_tag="ACG930_001844"
     CDS             4497..4991
                     /locus_tag="ACG930_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002365976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFQ0519002.1"
                     /translation="MKFIKDVTTLEELKRVYKKLALKYHPDMGGTDKEMAQINNEYEA
                     LFDKLKNTHKNKEGEYYQKETTETPQEWQEIIHKLLTLKMENVSIEVIGAFLWVSGNT
                     KPYKEELKALNMKWSNNKKSWYLAPDGYKKRSKKKYDMSDIRNMYGSQVVKEEQVKQK
                     TLTA"
     gene            5089..5505
                     /locus_tag="ACG930_001845"
     CDS             5089..5505
                     /locus_tag="ACG930_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010710134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0519003.1"
                     /translation="MIKTSAVGRLTKSSELRVTSTGKAVANFALACKRERLDKDGNAQ
                     TTFIQCVIWGKPAEVLAKYTQKGSLIAVNGELQSRSYDDQQGQTHYVTELVVAGFEFL
                     ESKETVQNREQKQQMPEMANAEPFYGMDDMEPPAYH"
     gene            5529..6113
                     /locus_tag="ACG930_001846"
     CDS             5529..6113
                     /locus_tag="ACG930_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HFQ0519004.1"
                     /translation="MKKLIGKKWLLLTAVATFLLSGCASLEQKAQDSVKEVTENVTQT
                     ISNDQRIPADFVRHVDGDTTVLKIDGKEQKVRFLLIDTPETVKPKTKVQPFGLEASKR
                     TKELLSNASEITFEYDQGDKTDRYGRALGYIFVDGTLLQKTLVSEGLARVAYIKEPNT
                     KYLSELEQAQEQAKNESLGIWSIPGYVTQRGFSK"
     gene            6224..6490
                     /locus_tag="ACG930_001847"
     CDS             6224..6490
                     /locus_tag="ACG930_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016614869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFQ0519005.1"
                     /translation="MATTKKKPIHVNVDENLKEEAEQLFDDLGLNMTSAITIFLKQSI
                     NEQAIPFMINKGNKETLQALKDIKEGNVHGGFSSVEDLMEDLNA"
     gene            6483..6758
                     /locus_tag="ACG930_001848"
     CDS             6483..6758
                     /locus_tag="ACG930_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HFQ0519006.1"
                     /translation="MLEIFYTNQFKKDFKKAKKQGKNLEKLKEVLVLLQEQQTLPPKY
                     KDHALTGNYIGTRECHIEPDWLLIYKIDGDKLILTLARIGSHSELFR"
     gene            7561..7746
                     /locus_tag="ACG930_001849"
     CDS             7561..7746
                     /locus_tag="ACG930_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519007.1"
                     /translation="MNELQLKLDLEKAQLEYQKLSQAINENDTVTLLLNYGCLKNAND
                     RLNQLSFLLNHIEWKDV"
     gene            7768..7914
                     /locus_tag="ACG930_001850"
     CDS             7768..7914
                     /locus_tag="ACG930_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HFQ0519008.1"
                     /translation="MTIVETLEVAVYVYAESEEQAHELVSNMYYDQEIILTEENHETT
                     EFII"
     gene            8145..8924
                     /locus_tag="ACG930_001851"
     CDS             8145..8924
                     /locus_tag="ACG930_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cas9 inhibitor AcrIIA9 family protein"
                     /protein_id="HFQ0519009.1"
                     /translation="MDFQNIQTVKELTHALKQYNQNLATTIFDDTQGYISVAFKKDKI
                     EKNGNDFQFLCFYPNYEVALYPVVTLLSYLEKLPEQATVAIKDPDGNYSSLYLTIDET
                     IDKGTKYKWLVISDRLSYERFYLTSQLTIQEQALEKMLKELETEPNNRLEAIHDWLCQ
                     QTDKDLLVGILKENRTLKGAEAYCTQKAYEIRNGNGAMASHITVFNWVREYYTLDELP
                     TDKPKIQATIKSDYINQKIQRPTPVETKNNNEIDLFEGEDF"
     gene            8924..10183
                     /locus_tag="ACG930_001852"
     CDS             8924..10183
                     /locus_tag="ACG930_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002365986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HFQ0519010.1"
                     /translation="MNTTDYVENKLQPPRAFFEWCYSSFRTYVWKNKNETIVSSTRKH
                     DWIIEKKLRKNSRLTFYDSSSCFQIILSTSKRIEVQTYKVISEYENGVQCFREQLECI
                     EIFSNNQHIKIGKICLPVYYGYNMGIALYPNEWKKRLERVSELKYLNLERLNVDNLAT
                     TYKYRTLIEFAQKINAHKLAYDVMSGAVDMRILTKNCLRKYKTFLKNTDNSLKEIQLK
                     QTFESLNIPMVKGIEKYVLKSDISDFPNEIGAVKFQNWLVKQGKSFKYYQDYLNMLTL
                     LKIEINKRNQLPPDLEVAHDCAVDRINQLNYEKRDKEINERLKQLRKYERDIDGYTFV
                     LPKRANDIKKEGKALNHCVASYISRHAKGETTIIFVREKKNPQKSYFTLEYNYNRVVQ
                     LQGKKNRQKVPDELKQAVDKWVKVIKD"
     gene            10833..11561
                     /locus_tag="ACG930_001853"
     CDS             10833..11561
                     /locus_tag="ACG930_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519011.1"
                     /translation="MTRLEQAQGKLQRLKRESEEMHHLIRAEHDRIPFGQPNIIGRGD
                     IYKKVNGYHDRAIKLLKEQEKQEKRVEMLEKVEDFKEKNELIKDVHVVGKSSYATVGA
                     KTSVNNIDYFKNELKELEKANEKAKAYNKTKPAIKARTFGAVITKLKNKIATLEQMKE
                     ADENKVVSERTKELIESGAVTQWKKKPIFYFVKGLRKVALEIDENGEFFISNYYPACT
                     DADKEFISKLLDPAAESRKKETFC"
     gene            11748..12182
                     /locus_tag="ACG930_001854"
     CDS             11748..12182
                     /locus_tag="ACG930_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002393005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519012.1"
                     /translation="MRRLSNTTMANETLKKEAWYRMMLTDLSSSVIDEFMETGKCHYT
                     SNYFQGENILVTEEIEAIIKTVEKKYGFLVYYVTENKTADGQRFLSLFYVGRDTSDWL
                     YCHRDLESYRQYVYVVNTTNPAFSEFGMIQFDPILGSLLRTA"
     gene            12268..12606
                     /locus_tag="ACG930_001855"
     CDS             12268..12606
                     /locus_tag="ACG930_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519013.1"
                     /translation="MSMEIRELIIIEDPCFYQYTTIKELESFNTSELTIALSVLRKEQ
                     RRLKEKVYHSGSGDQVDKNNVKLINKYRANLEKLLFIKQGYIPDAITQNMIDTLIKNN
                     KKSIQKIQKG"
     gene            12655..12828
                     /locus_tag="ACG930_001856"
     CDS             12655..12828
                     /locus_tag="ACG930_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002393256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519014.1"
                     /translation="MAEKIDLNKLYHESKKERTEKQTKMERALEGVVCGFPRNTDDDP
                     ILKNSKTQENTNG"
     gene            12821..13480
                     /locus_tag="ACG930_001857"
     CDS             12821..13480
                     /locus_tag="ACG930_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002393257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HFQ0519015.1"
                     /translation="MDEKRKDKIQRLLALANDANDEESMTALAKAQELMLAYGIDEEE
                     VFHYQQHQRQEKVIDKVIYKGRPHKWVYRLAGIIAKNFRVKNYYQSSSDIELHYVGLT
                     TDVEIAEITFLYAKGSVAFCSKEFMKQPEIKRKYKRKWQLKQDYIEGYLTALSSVFEA
                     QVLTNGYELALQLPVAVHEEVSKLGLVKGKDTSHHVENFDAFHSGYQEGLQFKSKELI
                     N"
     gene            13609..13767
                     /locus_tag="ACG930_001858"
     CDS             13609..13767
                     /locus_tag="ACG930_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519016.1"
                     /translation="MDVLNLMHAQGVVIGLKKTYAVNVYRKRTKKADKKLFAFFTYIF
                     YTIKKRGF"
     gene            13871..15331
                     /locus_tag="ACG930_001859"
     CDS             13871..15331
                     /locus_tag="ACG930_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase domain-containing protein"
                     /protein_id="HFQ0519017.1"
                     /translation="MNKFQSWLMANKNLLITSVVMCQVLVLSIGIINFPYIDDTGRQI
                     DGNTDFARSYSRWGSEIGSWLVQGSRHLTDMGLWTHILSGFIVSVTGIIIVYSFHKKL
                     SLLALTAAMLVGFNPWFLQNLSFRFDSPYMSLSLLFSVLPFLFWNKNKVLFLVVSILS
                     IFLMCNTYQASSGIYVVMVLALSLKQLLDNQSFIAVLKKAIVAMISYISAMFLYLIET
                     KFNPEIATRGGMTTIASVKDIPKTILVNSQMYLSKITEQSTKLWILLFFILVIFFVLS
                     TVLNAKVSPVKSFLYAVLFLFLGSILSYGVFLIFPEKLLLISPRYGYGFSFFVVSIIM
                     LTLSNTSKNVLGYVSKTAVCLFCVYLLSFTFVYASALSHQKESFERQSMILADDLKDL
                     VNRDTVTVHSTSLFKDSPVFANSSKNYPILKELVPPNEALYWPNQFLFRTYTGLNVNM
                     EIFDINALNKEESELMKSNYYHDIYVKDSEVFVHVK"
     gene            15711..16085
                     /locus_tag="ACG930_001860"
     CDS             15711..16085
                     /locus_tag="ACG930_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HFQ0519018.1"
                     /translation="MENIFDLNKGLSRRKYWYYQCILFVFGLGIETFSMFVYKKSLIE
                     NNYLKYFVINGPFDFYNFLRIVFFIMIIIGFLFQARRFVDIGWSKFVALLSLLPLVGI
                     ITTGICLFKKGKDNKTDSSQVS"
     gene            complement(16105..16341)
                     /locus_tag="ACG930_001861"
                     /pseudo
     CDS             complement(16105..16341)
                     /locus_tag="ACG930_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002399458.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16584..17243
                     /locus_tag="ACG930_001862"
     CDS             16584..17243
                     /locus_tag="ACG930_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfX family protein"
                     /protein_id="HFQ0519019.1"
                     /translation="MEENNIESKDNLFKEIGEKMYPLFFNRNFGLATKSEIESMLFYS
                     YLKHKINSNSDYSDRTLSRELGISEVKVRNLKRTCYARYEDAIDFPKLLTSLSKEGSN
                     LMFFKIYTDNNDVLCRISISEVVYYDELRTQLNNSGILFKKNPGSNYVELSMADAIIF
                     FDQDSISKESLDLKNLIDKMKQLNFKTNTKMDIDKILEGTKAGRMKNVVEAMMKLSNS
                     I"
     gene            complement(17502..17825)
                     /locus_tag="ACG930_001863"
     CDS             complement(17502..17825)
                     /locus_tag="ACG930_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519020.1"
                     /translation="MKKIVWIYSVNLKGMGLYGNSTTMPLRQAQKFQETIKTNLPSDV
                     TVDFISYDTSSTEIPKADLIVYNDIDSRYLSDDLKNNGIVIPFKDMISNNTREIEKKI
                     LLAIK"
     gene            18061..18255
                     /locus_tag="ACG930_001864"
     CDS             18061..18255
                     /locus_tag="ACG930_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519021.1"
                     /translation="MSKLLRELTDKEIQSSLSNGGSTCSMYKALLPGHIAACAASAYF
                     YGSSGCTAMRYVSEYIRKNC"
     gene            18334..19479
                     /locus_tag="ACG930_001865"
     CDS             18334..19479
                     /locus_tag="ACG930_001865"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0519022.1"
                     /translation="MLRNFSVIIICKNEERVIKRCIESIQKNLKKNDEIIVVDTGSTD
                     NTIKIISSIENVKLFNYEWKDDFADARNFGISKAKKDWIFFIDSDEIMSKGCLEQLNA
                     SINEAMAYSENNEKLVFSPKAVNTDDSVFYNAGRIFANDGNIKYEGCVHEYPVVTDKS
                     LTLVSLKLPRVIVRHDGYEKEVRADKNKTVRNITLIKKILQEEPNNSQYYYYYYRDSK
                     PLITIEEYEQGMLNFFEKFPDSPYIDQVVRDLAYHYIQVGKNELAEEYINMLFESAEN
                     GAKENYHLAILYTGMNEMGKIKAQQKDILKLLVYAHDNVLQQEEELFDKGYIFDDLIS
                     ILFFQIEEYETAYKICEKLDSCGYASNISKMISKLKVVLSPNSKNFR"
     gene            19571..20725
                     /locus_tag="ACG930_001866"
     CDS             19571..20725
                     /locus_tag="ACG930_001866"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HFQ0519023.1"
                     /translation="MKYKVIPQIGEEDCGAACVAMIVENYFKKKISICEIRPLIKNTK
                     MGTSFFDLKRGLKRLGVDCKISQAVKQKDVFEEITYPFITQIYNETGIHYITVFEKKR
                     NKLIVGDSSKNRQLSISISKFLKKWIPYVLEMDFKRSNIVYQIEQKAKEISIWKIMNS
                     LKLQLFLSLCLSIIVYVASVIIANIYTLYFNILIPQNLGELALQLMFIYILINFFSFS
                     LTFINNFIYNSMSKKIDEKIIGKYFNGLLNKPNMAIESYEIGELLTNLSNVILIRQRF
                     LTYLQLLPISVLTITGSFYLLYLSDEKLSFFVILLVIVLSLIIYLSDSHYEKLSKELI
                     ETGQDFNDSVIDTFTNVSIIKQLGLEKEFGNRGKKKAYQLYYFSNKNVEF"
     gene            20799..21635
                     /locus_tag="ACG930_001867"
     CDS             20799..21635
                     /locus_tag="ACG930_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFQ0519024.1"
                     /translation="MITLNQLSSGVLLTFNALLAYVTNPILNLANLQSVLVQGKVAQE
                     KLYNILESQIVLYGNKSLVIENDDIFINFDLVSYDYDSNSKILKDISINICGNNIALS
                     GTNGVGKSTIGKLIARLYIPDSGSIEINGQNLIDISEESVSKNIIYVDGRESLFSSSV
                     SDNIKLGRNIKDKDIYDTLSKLKANSIFQNLDFENISDKQLSLGQMQIIKVLRATLSA
                     KNIYIFDEITNGLDECVKQNVVDYLFGLKGMKIFITHDKEVISKCEKEYTVKDMKIVR
                     RR"
     gene            21637..22047
                     /locus_tag="ACG930_001868"
     CDS             21637..22047
                     /locus_tag="ACG930_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0061077 - chaperone-mediated protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFQ0519025.1"
                     /translation="MKKIFISISILVITGILGMLMYNNITSEKTYYTETKFGKISELV
                     KKNDRIILFVEQDGCSSCKLVKPIINNYAKENKGIVYSVTANKEKDYNVQSEKYHIEG
                     TPTLIYFKEGKEVYRTNTGFTEDEFQNTIKKVEF"
     gene            22049..22573
                     /locus_tag="ACG930_001869"
     CDS             22049..22573
                     /locus_tag="ACG930_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFQ0519026.1"
                     /translation="MNKKEYLGIILIALASISIILFLYSNNRELKKANTMLQLEKQVL
                     IDNTDSFEYLNSITVDTFENRIKNKEDIFVYIGNSECADCSTFSKNLKNEVNNFPLKN
                     SLYLVEISRLHRNKKKWTEFKLKYGFDQTPAFILFKNGKVNSMIQWDEKKGLSSDSFH
                     RWLEENRNDIENLS"
BASE COUNT         8545 a         3312 c         4198 g         6656 t
ORIGIN      
        1 tggcaaaacg aaaagtgatt tcaaaggaag acgaacggaa gaaaataacc gaatcaaaag
       61 cctacaaaga ccgagaaaaa aataaatttg aagagtcgca acgcttcaca gatgaacaag
      121 aagaagcgta tgaagaagca gtagaaacgg ttgatattga caagtataaa gaactatcca
      181 atcaattatt gcttggtaca agtgagttcg ggttgccgta tatcatcaac ttttcagagt
      241 tcaatcagca tgttcttgtt cccgcaacga caggttcagg gaaaacaacg ttacttcaat
      301 tacttgtcca acacgcagtc aaatttaatt ttccggtgat attgattgat ggaaaaggcg
      361 ctcgagatac attagaaagt atgcgagaaa ttgccaaatt ttatgacaaa gaagtgcatg
      421 cttttacgga tgatggcgat atgagataca acccagtaga gcatggaaat gacatatcta
      481 ttcgagataa gttagtgtct ttagccgaaa cagaaagtgt cttttattca ggcgcagcga
      541 aagctctttt gcaagtaaca attcaattgt tagacgagtt taaaggagcc aaggttactt
      601 tatctggaga cactcgtacg acagaaaccg ttgaacgaag tctaccattt gttcaacgat
      661 ttttacttcc gagaaatgtt ttacacttat ttgcggatgc gattttacca aacaatccca
      721 aactatttga gattgaagta gaaaagaaaa tacaaaaacc taagaaaaaa tcagtgaaag
      781 aaggaagcga gatactgcct gattcagacc ttgataaaga agaaaaagag gaagattcac
      841 aaattaagaa cagtaaattt agaaacattt cccaactagg aatagcacaa aaagaaacgg
      901 aaacgattgt ccttaatcca gaaacattag atttagactc gtactattta ttactaaaac
      961 gaaacctaag atatttgcca acagacaaag aaacaggaga aaatatcaaa caaaaattgt
     1021 tcgaacgatt atttattcgt tatgaacata aagattcacc gttttatttg tatgccacat
     1081 cagaagcatt acagacaaac attaacatgt tattggacag tgagttagga aaattatttg
     1141 atactaaaaa cgcaaaaaat gttctcgatg tgcaagaaat tgtcaatcaa cgaaagttag
     1201 tttacgtatc gttcaatgga ttgatttaca aagaatatat ccgcacttta gcgcaaatgt
     1261 tagtcggaga cgtaaattat tttgcttctg aaatgtatcg aaaaaatgtg aaacgtgaag
     1321 tccttgtgat ttttgatgaa cctgcttctt atctaaatga aacgtttatt gatatggtaa
     1381 ataaaggtag aggtgcaggt gtttacggta ttttcacccc tcaaacgatg gcagatattg
     1441 caaaattagg cgataaatta atggaacaac ttgtcggaaa tgttaatact ttgttcattg
     1501 gaaagaccaa cgaaaaaggt gaagccgagt attggagtga aacaatggga acgtaccaag
     1561 acattgatgt aacttcagtt acggaacaag aagatggcta ttcagatgtt ggaaaatctg
     1621 attggtcagg agatagagga accaaacgta atgtagatcg cttcaaaatt agtccaaaca
     1681 agataaaaga attgcgtaca ggggagttta ttatttatcg tacagcagaa aatgtaaacc
     1741 ttccaccaca gaaagtttac gtgcgaaacg cattaaattg gcttaaaaat aatagtaaga
     1801 tttagaagaa atagcaaatg aaaaacgaga gtagccatag agtaagcgta gagtaagtat
     1861 agagtaggta tagaataaaa aatctaggag agcggtcctc ggcgcttggt ataaaaggct
     1921 ttctccgcct gcaaaattcc tgaccatttt cgctcaacgt gggttaaaac ccccattaag
     1981 cgaaaatggt caggaatttt gcaactacga aaaaaatacc aagcgccgag gacaaacaga
     2041 atagagtaaa aaaatagaat gagtaaggtg atagaagtaa taaaaattaa agaaaaaagt
     2101 tcaaaagata aagttcaaaa gattaacaac taccccttgc gatagacgcc ccttcaccaa
     2161 accttgaagg gactatcgcc caaagcaaca acctcctaaa tcctccacca aaacttggag
     2221 gacttaaaag ctgaaaaaga atttctacac gttgttccga aactcttttt caatgaaaca
     2281 aataggcttt gcctatttgt actttttata gaaatgcggt gatattttga aaccattact
     2341 atataactat tacattgatt acactaagaa agataaaaca aggctaatta ttttatgtct
     2401 actccatgaa ttaagagtta tctcagttca acaattaatt gactttttcc aaattgaacg
     2461 gttatcagca gaaagcacag tttataagca cttaaattta ttaaaaacag atggattaat
     2521 tgcccgatca aaaaatggaa tgcacacgtt ctattaccta acaaaagaag ggcataatta
     2581 cattggtggg tactacacct tgccaaaagt tcctgaatac aatttacaac accacttaca
     2641 aattaatgat tatctgataa aaatgttgga actttgtaat aagcacccgc accttaaggc
     2701 ggtagtatca gaacgtcgaa aagtatatga agtaaaggac gagaagaaaa atcaaaaagg
     2761 cgtaaaatac tttgttcctg acttcatttt tatgtttttg gatagtattg gacgagaagt
     2821 agagtggcaa tttgaaatag aattaacact aaaaacaaaa cgacgttata gtcagggtgt
     2881 gtttccgaaa tacattaaac atttaaaaaa ttatgaagat gcacgcttaa tttatgtaac
     2941 acctagttca atcattaaag aagaacttga tatgtttaaa gaatatttta ttgacaaaga
     3001 aggggacgag tacaaagaag tgtttgatcg attgcatgtt ttttcagctg aagaatttga
     3061 aagtgaactg aaacgattac tagaaaaaga taaattcatt aattgggagt gagtttcatg
     3121 agaagaatag agaaagaatt caacaagaag ctagccggtt acgaaagaga gttaaaaaaa
     3181 ttaggatgtc tggatgatga aacaggactt attcccataa gcaaaagacg atggcatgtc
     3241 atttggtggc aacctgttac acttgcaaaa acaatcgtga gatcttatcg attaacgcta
     3301 gataatcaaa acttatgtat tttaggagat gtagaaatca ctatttatca tgatggaaca
     3361 tatggtattt ctaaagaagc tgtcccaatt tttattaatg acttattgtc tttaaaaaag
     3421 ttaattacta ttttctatgg aacacctttt aacttaaatt ttgaaaaaat tcgctgcgtt
     3481 aattttaaca ggtattgtgt ctctattcct gaaatttatg tcgagaaatt tgaagtatta
     3541 ataaactact tgataatttt aagtagctgc ttacatgaag taaaaaagca cgtagaatat
     3601 gattaacaag cttttcttct ttcagaagaa caccaataga ttggttgagt tcgtatacgc
     3661 tcacctaaga gaggaaaaga acgaagtcaa gcttcgttct tttttctacg tcggagaacc
     3721 gacgtagtga ttcagacgca aaaaccatgc gtctgaatca ggcccgtttt taggaagggc
     3781 tagtgtgttt gatttatcag ttctcacagc cgtgtaattt ctaatattcc ctaatcgtat
     3841 atcagtcact cggcgagtat aacctaaaac ataacctgtc ggaggtcaag ggcaagtggc
     3901 atcggcaagc cgacccttgt cctccgacag aacatgtttt ctagtcggtt atgccgaacg
     3961 accgatatac gaaaagggaa tctaaccaga atttcccctc tgacctttga aaactgaaaa
     4021 gcgaaatcaa acaaacaggc cttcgtctaa aaacgagcct aatcaaacct taggggttgc
     4081 acccctaaca cccggcgcct cactctctca accgaaaagg ttggttggaa aagcgttgac
     4141 aaaaacatat ttatttattg gttgtttgaa tataaaaaat gaaagaagga aagcaaaatg
     4201 ctaacaacaa aagaaaaaaa cagatttaaa aaaatggtag aaggaaacaa aacgtttcat
     4261 tattcttatg tcgatagact tagacaagat gtaagatatt acgttaatca atgtgaatca
     4321 gctgttaaag ctagagaaag catggaaatc ttagaattta tctacagtct attttctgat
     4381 aaagagttac cagcatggta cacaaaagcc gaccttgaaa atgataaaaa atcaattgaa
     4441 aaattggaac gctgggcagc ttagctgttc agcaacaatc agaaagggcg attagcatga
     4501 aatttatcaa agatgtaacg acattagaag aattgaaacg cgtatataaa aagctagctt
     4561 taaagtacca ccctgacatg ggcggtactg ataaagaaat ggcgcaaata aataacgagt
     4621 atgaagcgtt gttcgataag cttaaaaata cacacaaaaa taaagaaggt gagtactacc
     4681 aaaaagaaac gacagaaaca ccgcaagaat ggcaagaaat catacacaag ttgttaacgc
     4741 taaaaatgga aaatgtttca attgaagtga taggcgcatt cttatgggta tcagggaaca
     4801 caaagcctta taaagaagag ttaaaagctt taaatatgaa atggagcaac aacaaaaagt
     4861 cctggtattt agcccctgat ggatataaaa aacgtagtaa gaaaaaatac gatatgagcg
     4921 atattcgcaa tatgtatggt tcgcaggtag tgaaagaaga acaagtcaaa caaaagacat
     4981 taacagcgta aataggaatt gaattacatt aggaaaaaat taggttctac gtccaaagag
     5041 gttttacctc tttggacgac caaataaaaa agaaagaagg aatcaaaaat gattaaaaca
     5101 agtgcagtag gaagattaac aaaaagttca gaactaagag taacgtcaac agggaaggcc
     5161 gttgctaatt ttgcattagc ttgcaaaaga gaaagacttg ataaagacgg gaatgcccaa
     5221 acgactttta ttcaatgtgt aatctggggg aaacctgcag aggtgttagc aaaatatacg
     5281 caaaaaggtt cattaattgc agtaaatggt gaattacaat cacgttctta tgatgatcaa
     5341 caaggacaaa cgcattatgt tacagaatta gtcgtagcag gctttgaatt tttagaatca
     5401 aaagaaactg tacaaaatag agaacaaaaa caacaaatgc cagaaatggc gaacgccgaa
     5461 ccgttttatg gtatggatga tatggaaccg cctgcttatc attaaaattt atctgaagga
     5521 gggagaaaat gaaaaagtta atcggtaaaa agtggctgct gcttacagca gtagccactt
     5581 ttttattatc aggatgcgca agtcttgaac aaaaagcaca ggatagtgta aaagaagtta
     5641 ctgaaaatgt tactcaaact atttcaaacg atcaacgtat accagctgat tttgttaggc
     5701 acgtggatgg cgataccaca gtattaaaaa ttgacggaaa agaacaaaaa gttcggtttt
     5761 tattaattga cacacccgag actgtgaaac cgaaaacaaa agttcagccg ttcggattgg
     5821 aagctagcaa acgtacaaaa gagcttttgt ctaatgcttc agaaattact tttgaatatg
     5881 atcaaggcga taaaacagat cgctacggcc gagcgttggg ttatattttt gtagatggaa
     5941 cattactaca aaaaacactt gtgagtgaag gtttagcacg tgtggcctat ataaaagaac
     6001 ctaacactaa atatttgtca gaactagagc aagcccaaga acaggctaaa aatgagtcac
     6061 tcggaatctg gagcatacca ggttatgtga cacaacgggg gtttagtaaa taaataagaa
     6121 atcgctatga attattgaaa gtttttggcg agaaattata acacattatg ttgttgttaa
     6181 caacataatg tgttataatt atatacataa aggaggggta aaggtggcta ctacaaaaaa
     6241 gaaacctata catgtaaatg ttgatgaaaa tttaaaagaa gaagcagaac aattatttga
     6301 tgatttaggg ttaaatatga caagtgcaat tacgattttc ttaaaacagt ctattaatga
     6361 gcaagcaatt ccttttatga ttaataaggg aaacaaagag actctacaag cattaaaaga
     6421 cattaaagaa ggaaatgttc atggtggatt ttcttccgtg gaggatttaa tggaggattt
     6481 aaatgcttga aatattttac acgaaccaat tcaaaaaaga ctttaagaaa gcaaagaaac
     6541 aaggaaagaa tttagagaaa ttaaaagaag tattagtact tttacaagaa cagcaaacat
     6601 tgccgccaaa gtataaagac catgcactaa caggaaatta tataggtaca cgagagtgcc
     6661 atattgaacc agattggtta ctgatttata aaattgacgg tgataaattg atcctaactt
     6721 tagcccgaat aggctcacat agtgaattat ttcgatgaat cggaaagata ttacaaatca
     6781 ataaaaaaca ctactaaacg accagacgaa tagtagtgtt ttttgattat gcgattgtac
     6841 taagcaattt taacacaata aaaaataatc atgcaagact agggcgcaac aatctattat
     6901 agacgtgcgc cttttttagt tcgggaaaag ggaatgaatc cgttgttccg cggcggtgcg
     6961 gtagcccttg ctccaaaacc aacggattaa ctgctgcact caacacgagt caattaaacg
     7021 ttctctaccc attcgttccg attggggaac gtttcctttt cctactcgtt cctcgcttaa
     7081 cggaaaaggc cattgacacg agttgttcct tgtgggatca caaggaagcg ttccgcagtg
     7141 attaacattt ctagtaggta tttcatacct actagaaaac aaagtcaagg gcgttccggt
     7201 caaaaatccc ttttctgatg tcagaacagt gtcacgcgac ctttttcgtt ttcaggccgt
     7261 tcattttgca gtgtgtaacg cgctgctcac tgtttgctac agtaccacag ccagtcgaaa
     7321 aaacaagggt atataaacga gcaagctcgc ccttgttttt tctttatgtc tatggtcctt
     7381 ccacggcaca gcgagcgaca cgaacacact ggcgaaaatg aacaacctaa acaaaaacga
     7441 aaaagggggt agactacacc gtttgacgaa aaggaatttt tgaccgtcca gcttcacttc
     7501 ctcaaacgcc taacaaaaat ggttgttcaa aacccaaaaa cctgaaagga ggtggttaaa
     7561 atgaatgagc tacaattaaa acttgaccta gaaaaggcac aactggaata ccaaaaatta
     7621 agccaagcaa tcaatgaaaa tgatactgtc acgctgttat taaattatgg ttgtttaaaa
     7681 aatgccaatg accgtttaaa ccaactatca tttttgttga accacattga atggaaggac
     7741 gtgtaagaat ggctgaaaaa atactgtgtg acaattgttg aaaccttaga ggtagctgta
     7801 tatgtttatg cagaaagcga agaacaagca catgaattag tttctaacat gtattacgac
     7861 caagaaataa tcttaacaga agagaatcac gaaacaacag aatttatcat ttaaaacaac
     7921 gaaagaggtg aaaaagatat tttagaggta ttgaattata tccacgaaaa aagcacaaaa
     7981 aaagaaacct tttgccacta acaaaagatt tctaaagaat tggtagttat acctgaataa
     8041 atttgtaatt caagtataac gtatctcatg acctttgaca agtgaatttc ccccaacctc
     8101 ttattcataa gaggttggac taacaaaaga aacgagggaa cgttatggat tttcaaaata
     8161 tacaaactgt aaaagaatta acacacgcac tcaaacaata caatcaaaat ctagcaacca
     8221 ctatttttga cgacacacaa ggctatataa gtgtagcatt caaaaaggac aagatagaaa
     8281 agaacggaaa cgactttcaa tttttatgtt tctatcctaa ttatgaagta gccctttatc
     8341 cagtcgtgac attactttct tatcttgaaa agctaccaga acaagcaacc gttgcgatta
     8401 aagaccctga cggtaactac tcgtcccttt atctaaccat tgatgaaacg atagataaag
     8461 ggacgaaata caagtggcta gtaattagcg acagactttc ttatgaacgc ttttacttaa
     8521 ctagtcaatt gactatacaa gagcaagcac tggaaaagat gttaaaagaa ctagaaaccg
     8581 aacctaacaa tagactagaa gccattcacg actggctatg ccaacaaacc gataaagacc
     8641 ttttggttgg tattttaaag gaaaatagaa cattgaaagg ggcggaagct tactgcactc
     8701 aaaaggccta tgaaatacgt aatggcaacg gggcaatggc tagtcatatt actgttttta
     8761 actgggttag agaatattat acgcttgacg aactgccaac ggataagcca aaaatacaag
     8821 cgacaataaa aagcgattat atcaatcaaa aaatacagcg accaacacca gtagaaacca
     8881 agaataataa cgaaatagat ttgtttgagg gggaagattt ttaatgaata ctactgacta
     8941 tgtagagaat aaattacaac cgccaagagc gttctttgaa tggtgctact cttcttttcg
     9001 gacatatgta tggaaaaata aaaatgaaac cattgtttct tcaacaagaa aacacgattg
     9061 gataattgag aaaaaattga gaaagaactc tcgattgacc ttttatgatt caagcagttg
     9121 ttttcagatt atactaagta caagtaagcg aattgaagta cagacctaca aagttatttc
     9181 agagtatgaa aatggagtgc aatgttttcg tgaacagcta gaatgtattg aaatattttc
     9241 aaataatcaa catatcaaga ttggaaagat atgtttacct gtatattatg gttacaatat
     9301 gggcatagcc ttatatccta atgaatggaa aaagcgttta gaacgtgtgt cagagttgaa
     9361 atatctaaat ttagagcgat taaacgttga taatttagct accacgtaca aatatagaac
     9421 cttgatagaa tttgctcaga aaataaatgc tcataaatta gcatatgatg ttatgagtgg
     9481 tgcagtagac atgcgaatac ttacaaagaa ctgtttaagg aagtacaaaa catttttaaa
     9541 gaatacagac aatagtctaa aagagataca gctaaaacaa acatttgaaa gcttaaacat
     9601 accaatggta aaagggattg aaaaatacgt attaaagagc gacatatccg attttccaaa
     9661 tgagattggc gctgttaagt ttcagaattg gttagtaaag caaggaaagt catttaagta
     9721 ttatcaagac tacctcaata tgttaacgct cctaaaaata gaaataaaca aacgtaatca
     9781 gttaccgcca gatttagaag tcgcacacga ttgtgcagta gatagaatta atcagttgaa
     9841 ctatgaaaaa agggataaag aaataaatga acgtttgaaa caactaagga agtatgaacg
     9901 agatattgat gggtacacat ttgtgttacc taaacgagca aacgacataa aaaaagaagg
     9961 aaaagcacta aaccattgcg tagcaagcta tataagcaga cacgcaaagg gagaaacaac
    10021 gattatcttc gtaagagaga agaagaaccc tcaaaaatct tatttcacat tagagtacaa
    10081 ctacaatagg gttgttcagt tacaaggaaa gaagaatcga caaaaggtac cagatgaatt
    10141 gaaacaagcg gtagacaaat gggtcaaggt cattaaagat taaacgttag gaatgctaag
    10201 aaaagaccgt tcttagcatt cctaaccgaa atctaggaca aaatccattg ttccgcggcg
    10261 gtgcagtcgc ccttgctcca aaaccaatgg attttctgct gcactcaaca cgagtcaatt
    10321 aaacgttcta ttcccattcg ttccgactgg tgaacgtttc tcttttccta ctcgttcctc
    10381 gcttaacgga aaaggacatt gacacgagtt gttccttgtg agaccacaag gaagcgttcc
    10441 gcagatttaa gttttttctg aagcagtttc actgctacag aaaaaaggcg ttggttctat
    10501 ggcatttttc tgtcactcgg ccccttcttg cggttatcat ttcttcagtg agccggcctt
    10561 gtgtacttgc gaatcataca acagccagtc gaaaacacaa gggtaaaatg cacgagcaag
    10621 ctcgcccttg tgttttcttt gtgtctgatg tctgttctct gcgcacccaa aacctcaaac
    10681 tcactgaaga aatggatcat aacagcaaac aaagaaagga gaggaccaca gaaaaatacc
    10741 gaaccaacga agttcaaaag aagcacccct tcctaaatct tcaaaaaaaa tgagttttga
    10801 aaaaaataaa aaacagaaag aagcgaataa aaatgactag acttgaacaa gcacaaggaa
    10861 aattgcaacg actaaaaaga gaaagcgaag aaatgcacca cttaatcagg gcggaacatg
    10921 accgtatccc ttttggacag cctaacatta ttggccgtgg ggacatttat aagaaagtaa
    10981 atggctatca tgatcgtgca attaaattac tgaaggaaca agaaaaacaa gaaaaaagag
    11041 tggaaatgct ggaaaaggta gaagatttta aggaaaaaaa cgagctaatc aaagacgttc
    11101 atgtggtcgg taaatcaagt tatgcgacgg ttggcgcaaa aacaagtgtc aataacattg
    11161 attactttaa aaatgaacta aaagagcttg aaaaggctaa cgaaaaagca aaagcctata
    11221 acaagacaaa accagcaatc aaagcgagaa cgttcggcgc agtaatcacg aaactaaaaa
    11281 ataaaattgc gaccctggaa caaatgaagg aagctgatga aaacaaggtg gtgagtgaga
    11341 gaacaaaaga gctgatagaa agcggtgcag tgacgcagtg gaagaaaaaa ccaatattct
    11401 atttcgttaa agggttgcga aaagtagcac tagaaattga cgaaaatgga gaattcttca
    11461 tttctaacta ttatccggct tgtacagatg cagataagga atttatcagt aagttattag
    11521 atcctgcagc tgaaagcaga aaaaaagaaa ccttttgctg aagacaaaag atttctagga
    11581 cgttaactat ttatagtcat gaataagtat agcgtacctt agaaaaatat tcaatgggtt
    11641 cctgccataa caatggagtt atggcaagga ttcattgcca ctcatagaat agaacaatta
    11701 tctaacagta acgaattaaa aaaaatattg cttttggagg aatacaaatg agaagattaa
    11761 gtaatacgac aatggccaac gaaactctaa aaaaagaagc atggtataga atgatgctta
    11821 ccgacctatc aagttctgtc attgatgagt tcatggaaac ggggaaatgc cattacacca
    11881 gcaattattt tcaaggtgaa aatattttag tcactgaaga aatagaggca atcataaaga
    11941 cggtcgaaaa gaagtatggc ttcctggtgt actatgtaac tgaaaataaa acagcggatg
    12001 gccagagatt tttatcatta ttctacgttg gacgcgatac tagtgattgg ctttactgtc
    12061 acagggattt agaatcttat aggcaatatg tgtatgtagt taatacgacg aaccctgcat
    12121 tttcagaatt tggaatgatt caatttgatc caatactagg cagtctttta cgaactgcat
    12181 agataaaaaa atatacattt tatggtatca gttgggcttt ttggcccagc tgaagcctaa
    12241 cgtaaggaat tataagaaag gtgggaaatg agtatggaaa tacgggaatt aattataata
    12301 gaagatcctt gcttttatca atatacgacg ataaaagaac ttgaatcgtt taatacgtct
    12361 gaattaacga ttgctcttag tgtgcttaga aaagagcagc gtcgcttgaa agaaaaagtg
    12421 tatcattctg gatctggcga tcaagtggat aaaaataacg ttaaattaat caacaagtac
    12481 agagccaatc ttgaaaaact gctgtttatt aagcaagggt atattccgga tgcaatcacg
    12541 caaaacatga ttgatacatt gatcaaaaac aataaaaaat ccatacagaa gattcaaaaa
    12601 ggttgagttt agcaaggcaa caaaaaacat ttaataaaag agaggatgta aaacatggcc
    12661 gaaaaaattg atttgaataa gttatatcat gaaagtaaaa aggaaagaac cgaaaaacaa
    12721 acaaaaatgg aacgagcgtt agaaggagtt gtgtgtgggt ttccaagaaa cacagatgat
    12781 gatccaattt taaagaatag taagacccag gagaatacca atggatgaaa aaaggaaaga
    12841 taaaattcaa cggttgttag cactagcgaa cgatgcgaac gatgaagaat caatgacagc
    12901 tttagcaaag gcccaggaat tgatgctagc ctatggaatt gatgaagaag aagtgtttca
    12961 ttatcagcaa caccaaaggc aagaaaaggt tatagataaa gtgatttaca aaggaagacc
    13021 gcataaatgg gtctacagac tagctgggat cattgcaaag aattttcgtg tgaagaatta
    13081 ctatcaaagt tcttcagata tagaattaca ctacgtaggt ttaacaacag atgtagagat
    13141 tgcagaaatt acatttttat atgcaaaagg tagtgttgcc ttttgctcaa aagagtttat
    13201 gaaacaaccg gaaatcaagc gaaaatataa acgaaaatgg caattaaaac aagactatat
    13261 cgaagggtat ttgacggctc ttagttcagt atttgaagcc caggtactta cgaatggtta
    13321 cgaacttgca ttgcagttgc ctgtcgcagt ccatgaagaa gtctcaaagc taggcttggt
    13381 taaaggaaaa gacacctcac accatgttga aaacttcgat gcttttcatt ctggttacca
    13441 ggaaggctta cagtttaaga gtaaagagtt aatcaactaa taaaattatt aatggaggaa
    13501 agagtatgcc taatttggat tcctacttag aaagatttga aaactatcag aaggaacaag
    13561 aagaattaaa tgaaattttt gatccggacg ataggaggtg cagagtttgt ggatgtactc
    13621 aatttaatgc atgcccaggg ggttgttatt ggattgaaga agacttatgc agtaaatgtg
    13681 tatagaaaga gaacaaaaaa agcagataaa aaattatttg ctttttttac ttatatattt
    13741 tatacgataa aaaaacgtgg tttttagttt gaaaaccctg taagattaat atatggaccc
    13801 atttaatgta aacataaaag gtgttcgttt tcttaggggg gtattttaat aaaaattgag
    13861 gagtgaaaaa atgaataagt ttcaaagttg gcttatggcc aataaaaatc tgttaattac
    13921 aagtgtagta atgtgtcaag tgttagtctt aagcataggg ataatcaact ttccttatat
    13981 tgatgacacc ggcaggcaaa ttgatggcaa tacggacttt gctagaagtt attctcgctg
    14041 gggtagcgaa attggttctt ggttagttca agggagtaga caccttacgg atatggggtt
    14101 gtggacgcat attctttctg gattcattgt atcagtaaca gggattatca ttgtttactc
    14161 ttttcataag aagctatctc ttttagcttt aacagcagcc atgttggttg gctttaatcc
    14221 ttggttttta caaaatttaa gtttcaggtt cgatagtcct tacatgtctt tgagcctttt
    14281 attttcagtt cttccatttc tattttggaa taaaaataaa gtcttatttt tagttgtttc
    14341 tattttaagc atttttttga tgtgtaatac ttatcaggcg tcttcgggga tctacgtcgt
    14401 gatggtgtta gcattatcac tgaagcagct gttagacaat caatcgttta ttgctgtgct
    14461 taaaaaagcg attgtagcta tgattagcta tataagcgcc atgtttcttt atcttattga
    14521 aacaaaattt aatcctgaaa tagcaacgcg aggcggtatg acaacaatcg cgagcgttaa
    14581 ggatataccc aaaacaatcc tggtaaatag tcaaatgtat ctgtcaaaaa taaccgagca
    14641 gagtacaaag ctatggatac ttttgttttt tattctagta attttctttg ttttaagtac
    14701 ggttcttaat gcgaaagtat cgcctgttaa aagcttttta tacgcagtat tatttctatt
    14761 tttaggctct attttgagtt acggcgtctt tctaatcttt ccggaaaagc ttttgttaat
    14821 ttcgcctaga tacggctatg gatttagttt ttttgtagtt tcaattatca tgcttacttt
    14881 gtcaaatact tctaaaaacg tgctaggata tgtgtcaaaa acagcggttt gtcttttctg
    14941 tgtctacctt ttatctttta catttgttta tgctagtgcg ttaagccacc aaaaggaatc
    15001 ttttgaacga caaagtatga tattagccga tgatttaaaa gacctagtga accgtgacac
    15061 ggtgaccgtg catagtacgt ctttatttaa agattcgcca gtatttgcta atagttcgaa
    15121 gaattatcct atattaaaag aactggttcc accaaatgaa gccctttatt ggccaaatca
    15181 gtttttattt agaacgtaca ctggtttaaa tgtgaacatg gagatctttg atattaacgc
    15241 gttgaataaa gaagaaagtg agttaatgaa atctaattat taccatgaca tttatgtaaa
    15301 agattcagaa gtatttgttc atgttaaata atcctgaaat aaaagtaata tcaaggcaat
    15361 tgaaaggccg gggtagatac tgtaaaataa aaatagctat ttcagattta actatttact
    15421 tacagactga ataaattgag cgttcagttc tatgagtact tgttagaaac gaaaggctaa
    15481 aataagttat aaccttagag actgtctccc cccaagagac agtcttatat attgtttaat
    15541 agataattac tttactaaaa taggataaat tcaatcagaa atgtatactt tgtaaggaaa
    15601 aaatcatagc tgttttagga tattatttgc tattttatgt atttgccaat tacaatggta
    15661 ttgtaaataa atacataaag tagcattagt aggttttggg ggatatagat ttggaaaata
    15721 tttttgattt aaacaaggga ttatcaagaa gaaaatattg gtattatcag tgtatactgt
    15781 ttgtgtttgg attagggata gaaacttttt caatgtttgt atacaaaaag tctctgattg
    15841 aaaacaatta tttaaaatat ttcgtgataa atggtccatt tgatttttat aattttctta
    15901 ggatcgtgtt ctttataatg attattatag gttttctgtt ccaagcaaga aggtttgttg
    15961 atattgggtg gtcgaaattt gtagctttac taagtctgtt accgttagtt ggtattatca
    16021 caacagggat ttgtttattt aaaaagggaa aagacaataa aacagatagc agtcaagttt
    16081 cttgattgct atctgtttta tttattaaga gtattgtcta ttaaatgaat gacaagaact
    16141 tgcattgtaa gcagcttgaa tcgcagctga ccatgagagt ttatggaatg ctactgcaga
    16201 ccaaattcct ttcataatac aagcaccttg ttttgcttta gcttgttgat atttattcca
    16261 taaatgttta gggactttac tttttgcaaa gttgtcctaa taaccatcgt cactttgggc
    16321 atatgcagta gtaaagttta ctaacggata atacatgata aatttaaaag gtagggtact
    16381 ttttcgtaca agaatgattt tgtaagtatg aaacaagcta gttatatttc actagctatt
    16441 caatgaaata agtttttaaa gtagattgtt gatagatata ttaaaatttt ttttcatgta
    16501 agagtatgct aaaattgatg ttaagaatgg ttttccctag taataggtaa catcaaaata
    16561 aaggaaggtg taattctata cctatggaag aaaataatat agaaagcaaa gacaatctgt
    16621 ttaaagagat tggggaaaaa atgtatccgc ttttttttaa tcgtaatttt ggattagcaa
    16681 caaaaagtga aattgaaagc atgctctttt actcgtatct aaaacataag ataaatagta
    16741 atagtgatta ctcagataga accttgtcta gagagctagg aatatcggaa gttaaagtaa
    16801 ggaatcttaa gagaacatgt tatgcaagat atgaagatgc aattgatttt cctaaattac
    16861 taacctcgct gtccaaagaa ggctcaaatc taatgttttt taaaatctat actgacaata
    16921 atgatgtatt atgtaggata tctatttccg aggtagttta ttatgatgaa cttcgaacac
    16981 aattaaacaa tagtggtatt ctttttaaaa aaaatccagg atcaaattat gtagagttat
    17041 caatggcaga tgcaataatt ttctttgatc aggattctat cagcaaagaa agcttagatt
    17101 tgaaaaattt aatagataag atgaaacagt tgaattttaa aactaatact aaaatggata
    17161 ttgataaaat attagaagga actaaagctg gtagaatgaa aaatgtcgtt gaggctatga
    17221 tgaagctttc caactcaata taaacaaaga ggtcagaaac ttctaagttt tttgacctat
    17281 tgctttttcg tgtgtaactt ttttatttaa atggcataag tttttatcga tgaatggcaa
    17341 aagctaccaa aacaaatgga aaaaaccagt tgtatattac aactggtttt tttgaacgaa
    17401 atctcgttca atggatagct taactataat ataagtatac aaaatatgca agcgtttaca
    17461 ttaaataaaa aattgaattt ggtagtaggg tacatatgat tctatttaat agctaacaaa
    17521 atttttttct ctatttcacg tgtattatta gaaatcatat ctttaaacgg gataactata
    17581 ccattatttt ttaagtcatc acttagatat ctggagtcta tgtcattata tacaatcaag
    17641 tctgccttgg gtatttcagt acttgaagta tcatagctta taaaatcaac agtaacatca
    17701 gacggcaaat tcgttttaat tgtttcttga aatttttgtg cttgtctcaa aggcatagtt
    17761 gtactatttc cataaagacc catacccttt aaatttacag aatatatcca tactatcttt
    17821 ttcatttgta ttcccccttc taacatatta tttactttaa atatatcact ttgtaaaatt
    17881 aatacaagaa atatctacaa cgattttaag caatgtgata taatgatcaa tgaaagcgct
    17941 tacttgactt tgttccgtat acttaactat acatattttt taatacctac ttaatatgta
    18001 acaattactc tgtacataag gtagttaaac aactagaaaa ttattttgga ggagatattt
    18061 atgagtaaat tattacgtga attaacagac aaggaaatac aatcttcgtt atctaatggt
    18121 ggatctacat gcagtatgta taaagcgcta ttacctggac atattgctgc atgtgcagct
    18181 agtgcatatt tttatggttc aagtggctgt accgcaatga gatatgtttc agaatatata
    18241 agaaagaatt gttaaccatt caattttttt aatgtagttt atatagcatg ttaatttgtt
    18301 gtttaactat cttattctta ggaggatata tctatgctta gaaatttttc agtaataatt
    18361 atatgtaaaa atgaagaaag agtaatcaag cgatgcatag aatctataca aaaaaatttg
    18421 aaaaagaatg atgaaatcat agtagtggat accgggtcta cagataatac tataaaaatt
    18481 atatctagta tagaaaatgt aaaactattc aattatgaat ggaaagatga ctttgcagat
    18541 gcaagaaact ttggtatttc aaaggcaaaa aaagattgga ttttttttat tgattccgat
    18601 gagataatgt caaaaggatg tttagagcaa ttaaatgcta gtataaatga agcaatggcc
    18661 tactctgaaa ataatgaaaa gcttgttttt tcgcctaaag cagttaatac ggatgattct
    18721 gtattctaca atgcaggaag aatatttgct aatgatggaa acattaaata cgaagggtgt
    18781 gtacacgaat atcctgtcgt gactgataaa agtttaacgc ttgtttcttt aaaacttcct
    18841 agagttatag taagacatga tggttatgaa aaagaggtac gagcagacaa aaataaaaca
    18901 gtaagaaata taactttaat taaaaaaatc cttcaggaag aacctaacaa ctctcagtat
    18961 tattattatt actacagaga ttcaaaaccc ttgattacga ttgaagaata cgaacaaggg
    19021 atgctaaatt tttttgaaaa atttcccgat agtccttaca ttgatcaagt agtaagagat
    19081 ctagcttatc attatataca agttggtaaa aatgaattag cagaggaata tattaatatg
    19141 ttatttgaga gcgcagaaaa tggagcgaaa gaaaattatc atttagcaat attatacaca
    19201 gggatgaatg aaatgggtaa gataaaagcc caacaaaaag acatattaaa gttacttgta
    19261 tatgcacatg ataatgtttt acagcaagag gaagagttgt ttgataaggg atatatattc
    19321 gatgatttaa taagtatact gttttttcag attgaggaat acgaaaccgc atataaaata
    19381 tgtgaaaaac ttgattcttg tggctatgct tctaacattt caaaaatgat tagtaaactt
    19441 aaagtggttc taagtcctaa ttctaaaaat tttaggtaaa aggagtcaat tcttagatac
    19501 cataacttaa ttttattata agtaaatatc aacttaaatt aataatgctt tttagataag
    19561 gaagataaaa atgaaatata aagttatacc acaaataggt gaagaagatt gcggtgctgc
    19621 atgtgtagca atgatagtag aaaactattt caaaaaaaaa atatcaattt gtgaaataag
    19681 accgttaatt aagaatacaa aaatggggac ttctttcttt gacttaaaaa gaggactaaa
    19741 gcgtttggga gttgattgca aaatttcgca ggcagtaaag cagaaagacg tttttgaaga
    19801 aattacatac ccatttatta cacaaattta caatgagaca ggtattcatt acattacagt
    19861 attcgaaaaa aaaagaaata aattaattgt tggagactct agtaaaaata gacagctttc
    19921 aatttcaatt agtaagtttc taaaaaaatg gattccatat gttttagaaa tggattttaa
    19981 aagatcaaat atagtctatc aaattgaaca aaaagctaag gaaataagta tttggaaaat
    20041 catgaatagt ctaaaactcc aactttttct atcattatgt ctatctatta tagtgtatgt
    20101 agctagtgta ataatagcaa atatatatac tttgtatttt aacattttga taccacaaaa
    20161 ccttggagag ttagctttac agttaatgtt tatatatata ttaataaact tttttagctt
    20221 ttctttaaca tttattaata attttattta taactcaatg agtaagaaaa ttgatgaaaa
    20281 aattatagga aaatatttta acggtttact aaacaaacct aacatggcta tagaatctta
    20341 tgaaatagga gaattgctta ctaatctttc taacgttatt ttgatcaggc aaagatttct
    20401 gacatatctg caattacttc caatcagtgt tttgactatt actggtagct tttatttatt
    20461 atacctatct gatgaaaaat tatctttttt tgttatattg ctagtaattg ttcttagtct
    20521 aattatatat ttatctgata gtcactatga aaagctaagc aaggaattaa tagaaacagg
    20581 tcaagatttt aacgattctg taattgatac atttactaat gtaagtatta taaaacaact
    20641 gggacttgaa aaagaatttg gtaatagagg taaaaaaaaa gcttaccaat tatattattt
    20701 ctcgaacaaa aatgttgaat tttgactcga ttctaaatca aataaagtct tttgtactat
    20761 cgtcattcaa tattatttta ttttcaactg gtgtatattt gattacttta aatcagttat
    20821 cttcaggtgt cctgcttaca ttcaatgctc tactagcata cgtaactaat cctattttga
    20881 atcttgctaa cttacagtcg gtgttagtac aaggaaaagt agcacaagag aagctttata
    20941 atattctaga atcacaaata gttttatatg gaaataagtc attggtaata gaaaatgacg
    21001 atatttttat caactttgat ttagtatcat atgattatga ttccaactct aaaattttaa
    21061 aagatatctc aattaatata tgcggaaaca acatcgcatt aagcggaact aatggagttg
    21121 gtaagtctac aataggaaag cttattgctc gtctctatat tccagatagt ggaagtatag
    21181 aaatcaatgg gcaaaacttg attgacatat cagaagagtc tgtttctaaa aatattattt
    21241 atgtagatgg tagagaaagt ctcttttctt cttctgtatc agataatatt aagcttgggc
    21301 gaaatattaa ggataaagat atatacgaca cgttaagtaa actaaaagct aattcaattt
    21361 ttcaaaatct tgattttgaa aatattagtg ataagcaatt aagtttaggg caaatgcaaa
    21421 taataaaggt tttaagagca actctttctg caaaaaatat atatattttt gatgaaatca
    21481 ctaatgggct tgatgaatgt gtaaagcaaa atgttgtaga ttatttattt gggttaaaag
    21541 ggatgaagat ttttataaca catgataaag aggttatttc aaagtgcgag aaagaatata
    21601 ccgtaaaaga catgaaaatt gtgaggaggc gataacatga aaaaaatttt tattagtatc
    21661 tctatacttg taataacagg aattctagga atgcttatgt ataacaacat tactagtgaa
    21721 aaaacatatt atacagaaac taagtttggc aagatttctg aattagttaa aaaaaatgat
    21781 agaataatac tatttgtcga acaagatgga tgttcatcgt gtaaacttgt gaagccaatt
    21841 ataaataact atgcaaaaga aaataaagga atagtttatt ccgttacagc taataaagaa
    21901 aaagactaca acgtgcaatc agaaaaatat catatagaag gtactccaac attaatatac
    21961 ttcaaagaag gcaaagaagt ttatcgtaca aacaccggtt ttaccgagga tgagtttcag
    22021 aatactataa agaaagtgga attttaatat gaataagaag gaatatctag gtatcatact
    22081 aattgcctta gcaagtataa gtattattct ttttctatac agtaataaca gagaacttaa
    22141 aaaagctaat acaatgctac agctcgaaaa acaagtctta atagacaaca cagattcttt
    22201 tgaatatcta aattcgatta ctgtagatac ttttgaaaat agaattaaaa ataaggaaga
    22261 tatttttgtc tatataggaa atagtgagtg tgcggactgc tcaacttttt caaaaaacct
    22321 aaagaatgaa gtgaataatt tccctcttaa gaattcattg tatttagtag agataagtag
    22381 acttcataga aataagaaga aatggacaga atttaagtta aaatatggat ttgatcagac
    22441 tcctgcattt atattgttta aaaatggaaa agtgaatagt atgattcagt gggatgaaaa
    22501 aaagggttta agttctgatt cattccatag gtggttagaa gaaaatagaa atgatataga
    22561 aaatcttagt taataattca gaagagttag atcatatgta ttgaataaat tcagaaacaa
    22621 tttagtgcat agttaaaaag catgtaagct attccttgga aggtcagaaa cttaaaagtt
    22681 tttgaccctt tttttattcc tcatttcaca a
//
LOCUS       DAZKPE010000044        20937 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000044 DAZKPE010000000
VERSION     DAZKPE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.044"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            591..1280
                     /locus_tag="ACG930_001870"
     CDS             591..1280
                     /locus_tag="ACG930_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFQ0519027.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACG930_001871"
     CDS             1267..2475
                     /locus_tag="ACG930_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0519028.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACG930_001872"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACG930_001872"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFQ0519029.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG930_001873"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG930_001873"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFQ0519030.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACG930_001874"
     CDS             complement(6578..7273)
                     /locus_tag="ACG930_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFQ0519031.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG930_001875"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG930_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFQ0519032.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACG930_001876"
     CDS             complement(8472..8663)
                     /locus_tag="ACG930_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFQ0519033.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACG930_001877"
     CDS             complement(8684..9574)
                     /locus_tag="ACG930_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFQ0519034.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACG930_001878"
     CDS             complement(9561..10328)
                     /locus_tag="ACG930_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0519035.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG930_001879"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG930_001879"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFQ0519036.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG930_001880"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG930_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFQ0519037.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG930_001881"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG930_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFQ0519038.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACG930_001882"
     CDS             14899..15282
                     /locus_tag="ACG930_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519039.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG930_001883"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG930_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFQ0519040.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACG930_001884"
     CDS             complement(16226..17044)
                     /locus_tag="ACG930_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFQ0519041.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG930_001885"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG930_001885"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFQ0519042.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG930_001886"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG930_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFQ0519043.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="ACG930_001887"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="ACG930_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFQ0519044.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="ACG930_001888"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="ACG930_001888"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFQ0519045.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         5983 a         4258 c         3838 g         6858 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt atatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttatt
//
LOCUS       DAZKPE010000045        20455 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000045 DAZKPE010000000
VERSION     DAZKPE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.045"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..142
                     /locus_tag="ACG930_001889"
     CDS             <1..142
                     /locus_tag="ACG930_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0519046.1"
                     /translation="MDFNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFC
                     LA"
     gene            214..987
                     /locus_tag="ACG930_001890"
     CDS             214..987
                     /locus_tag="ACG930_001890"
                     /inference="COORDINATES: protein motif:HMM:NF014368.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519047.1"
                     /translation="MNEPLLFGTPMILNPYMLIPFVVAPIVNAWICKFFVDNLMMNGF
                     IYVLPWATPAPIGIFLDTNFQLISIVLIVLLLTLDAFIYMPFLKAYDKVLLKQEAART
                     EGEAISGGIVAEKPIEEMKSADPDPEISLQINKLSDRENSLKVLVLCAGGGTSEQLAN
                     ALKIGAEETKFNLVSKAAAYGNHYSLLPNYDVVVLAPQIKSFYKDIKQDTDKHGILLI
                     PTKGFEYIELTREPAGAIKFITEKLTDSKLKDELASYLS"
     gene            1048..2196
                     /gene="dgoD"
                     /locus_tag="ACG930_001891"
                     /pseudo
     CDS             1048..2196
                     /gene="dgoD"
                     /locus_tag="ACG930_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018926188.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008869 - galactonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
     gene            2190..3200
                     /locus_tag="ACG930_001892"
     CDS             2190..3200
                     /locus_tag="ACG930_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008671 - 2-dehydro-3-deoxygalactonokinase
                     activity [Evidence IEA];
                     GO_process: GO:0034194 - D-galactonate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HFQ0519048.1"
                     /translation="MVDEYMIKDIITIDVGTTNTRVSLWRDEELQEVFVYSQGVQKAS
                     LAGNNDTVKKILECSIKKLFKKYNILAEKTVIIASGMITSAFGLVEIPHLNAPVGIQE
                     LAISMKQFSFPEVCPQPIWFIPGVKTQCQDKSRLSSIQYDVMRGEETEAMAVFSLLKP
                     TISDEHIFVMPGTHTKFIKLDKNGRIVKSKTATTGEILSLLTKKSLIATDVHHRFYDE
                     LDESYLLSGFHSARSNGIGSAVFDVRILGQTHNASRNQRANYLLGAVLSSDIQLLENF
                     LEPNETVVLTGKKELREAIHVILNDLDNFSHPIIIIEANDLAGRGALLAGKKRGLLRK
                     EG"
     gene            3205..3831
                     /locus_tag="ACG930_001893"
     CDS             3205..3831
                     /locus_tag="ACG930_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFQ0519049.1"
                     /translation="MELENYPKATAILRGYTYEEAMLVIRVLSEFKHFIGVEVTTNNS
                     DHLKIIHDGKNRFGDKISIGVGTVVTVEQAEEAIEAGAEFMLGPQKFNDKIFKLAKRK
                     GVLTIPGAMSPTEIFKMFEMGADIVKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQ
                     TNAQNYLNNGASYVGIGSKFFEKSAVHQLNYERLMELAESFIDSLRVE"
     gene            complement(4225..5232)
                     /locus_tag="ACG930_001894"
     CDS             complement(4225..5232)
                     /locus_tag="ACG930_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0519050.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLIVRKSFIPKEE
                     V"
     gene            5699..7105
                     /gene="lacG"
                     /locus_tag="ACG930_001895"
     CDS             5699..7105
                     /gene="lacG"
                     /locus_tag="ACG930_001895"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFQ0519051.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            7128..7451
                     /locus_tag="ACG930_001896"
     CDS             7128..7451
                     /locus_tag="ACG930_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0519052.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVRKGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            7462..9144
                     /locus_tag="ACG930_001897"
     CDS             7462..9144
                     /locus_tag="ACG930_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFQ0519053.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVAATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFG
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            9351..10310
                     /locus_tag="ACG930_001898"
     CDS             9351..10310
                     /locus_tag="ACG930_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0519054.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEGDTIVGVKHKSAVITLIECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            10329..10556
                     /locus_tag="ACG930_001899"
     CDS             10329..10556
                     /locus_tag="ACG930_001899"
                     /inference="COORDINATES: protein motif:HMM:NF019322.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HFQ0519055.1"
                     /translation="MYQVFEEMGYPIKTVTRKLEVIKADDTISDLLDVEEGDPMFYFH
                     TQGFSLERLPVEYSISKYRGDINYFVFELAQ"
     gene            10771..11523
                     /locus_tag="ACG930_001900"
     CDS             10771..11523
                     /locus_tag="ACG930_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0519056.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(12116..13573)
                     /locus_tag="ACG930_001901"
     CDS             complement(12116..13573)
                     /locus_tag="ACG930_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFQ0519057.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(13595..13897)
                     /locus_tag="ACG930_001902"
     CDS             complement(13595..13897)
                     /locus_tag="ACG930_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFQ0519058.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            complement(13954..14433)
                     /locus_tag="ACG930_001903"
     CDS             complement(13954..14433)
                     /locus_tag="ACG930_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519059.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            14598..15371
                     /locus_tag="ACG930_001904"
     CDS             14598..15371
                     /locus_tag="ACG930_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0519060.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            15391..15819
                     /gene="lacA"
                     /locus_tag="ACG930_001905"
     CDS             15391..15819
                     /gene="lacA"
                     /locus_tag="ACG930_001905"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFQ0519061.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTREHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            15838..16353
                     /gene="lacB"
                     /locus_tag="ACG930_001906"
     CDS             15838..16353
                     /gene="lacB"
                     /locus_tag="ACG930_001906"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFQ0519062.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            16366..17292
                     /gene="lacC"
                     /locus_tag="ACG930_001907"
     CDS             16366..17292
                     /gene="lacC"
                     /locus_tag="ACG930_001907"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFQ0519063.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            17305..18291
                     /gene="lacD"
                     /locus_tag="ACG930_001908"
     CDS             17305..18291
                     /gene="lacD"
                     /locus_tag="ACG930_001908"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFQ0519064.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            18747..19415
                     /locus_tag="ACG930_001909"
     CDS             18747..19415
                     /locus_tag="ACG930_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0519065.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            19406..>20455
                     /locus_tag="ACG930_001910"
     CDS             19406..>20455
                     /locus_tag="ACG930_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0519066.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHI"
BASE COUNT         6637 a         3347 c         4392 g         6079 t
ORIGIN      
        1 aatggacttc aaccaagtca atcaaggatt catctcatcc gttgcgtcca aaagaaacca
       61 tatccctaga aaatcactaa attaccaaac accattagaa gtttttttga gttacgtaaa
      121 tggaaagttt tgtctcgctt aatttgacaa ataataaaat caaaacagct gagaacgatt
      181 ggtaaaactt cggttattcc ttgtattttt gcagtgaatg aaccactatt atttggaaca
      241 ccaatgattt taaatccata tatgctaata ccatttgtgg tggcgccaat cgtaaatgca
      301 tggatctgta aattttttgt ggacaatttg atgatgaatg gatttatcta cgtacttcct
      361 tgggcaacac ctgcgccaat cggaattttc ttagatacta atttccagct gatatcaatc
      421 gtattgatcg tgttgttgct aacattggat gctttcatct atatgccatt tttgaaagct
      481 tatgacaaag tattgctaaa acaagaagca gcacgtactg aaggtgaggc tatttctggt
      541 gggatagtag cagagaaacc tattgaggaa atgaaatcag ctgatcctga cccagagatt
      601 agcttacaaa taaacaaact ttcagatagg gaaaattctt taaaagtatt agttttatgt
      661 gcaggaggag ggaccagtga acaactagct aatgcgttga aaattggagc ggaggaaacg
      721 aaattcaatt tagtttcaaa agctgcagct tatgggaatc actattcatt attgccgaat
      781 tacgatgtgg ttgttttagc ccctcaaatt aagtctttct acaaagatat aaaacaagac
      841 acagataaac atggcatttt attgattccg acaaaaggtt ttgaatatat tgaattgacg
      901 agggaacctg caggggctat taaattcatt acggaaaaat taacagattc aaaattgaag
      961 gacgagctag cgtcgtatct ttcataatgg aatcattatc gatcaattgt cagattacga
     1021 aaatttcaaa agatagaagg agttcaaatg aagattacgg gatataaaac gtatatggtg
     1081 cctcctagat ggctattctt aaaaatcgaa acggatgaag gtattgccgg ttggggcgaa
     1141 cccgttattg aaggaaaagc ggcaagtgtc gaaacagcag ttcatgagtt tatggatcag
     1201 ttgctaggtg atgatccatc tgctattgaa ggctgatggt caaaaatgta ccgcagcagt
     1261 ttttaccgag gtggtcccat attgatgagt gctattgcgg gtattgacca agcgctttgg
     1321 gatatcaaag ggaaaacaat gggacagccg gtctttcaat tactgggtgg tgcagtccga
     1381 aataaaatca aagtgtattc ttgggtagga ggtgatcgtc ctcacgatgt aggggcagcg
     1441 gcactagaaa gaaaaaattc aggattcaaa gcaattaaaa tgaatgcaac agaagaaatg
     1501 cagattatag acagctatga aaaaatcgat gaagtagtgc atcgcattga ggcggtccgg
     1561 gatgcttgtg gtccgtattt cggtatagca gttgactttc atggtcgaat ccacaaaccg
     1621 atggcaaaag tgttagcgaa agctatagca cgctttaatc tgttgttcat tgaagaaccg
     1681 gtattgtcag aaaacaataa agcactaagt gcgattacac aactggtgga gaccccaatt
     1741 gcgactggcg aacggatgtt tagccgctgg gattttaaaa atattttaga gagcaacaat
     1801 gttgatatta ttcaaccgga tttatcacat gctggaggga ttactgagtg taaaaagatc
     1861 gcaaacatgg cagaagcgta tgatgttgct gtagccttcc attgtccgct aggcccgatc
     1921 gctttagctg cgtgtctgca gctagatgct gttgttcaaa atgcatttat tcaagaacaa
     1981 agtcttggaa tccattacaa tgatggcaat gatctgatgg actacattaa gaatccagaa
     2041 attttcgagt atgaagacgg ttatgtaaaa atcccacagt taccaggatt gggtgttatc
     2101 gtggatgagg agttggtgat tgaaaaatca aaaatcccta ataattggca taaccccgtt
     2161 tggcgacatg aagacggaag tatcgcggag tggtagatga atatatgata aaagatatta
     2221 ttactattga tgtaggaaca acaaatacta gagttagctt gtggcgagat gaagaattac
     2281 aggaagtttt tgtctattca caaggtgttc agaaagcatc attggcgggg aataatgata
     2341 cggtgaaaaa aattttggag tgttcaatca aaaaattgtt caaaaaatat aatattttgg
     2401 cggagaaaac agtgattatc gcttcaggaa tgataacttc tgcttttgga cttgttgaga
     2461 ttcctcattt gaatgcacca gtaggaattc aagaattagc aatatcgatg aagcaatttt
     2521 catttcccga ggtttgcccg cagcctatct ggttcattcc tggtgtaaaa actcaatgtc
     2581 aagacaagtc acggctttct tcgattcaat atgatgtgat gcggggagaa gaaacagagg
     2641 cgatggcagt attttcattg ctgaaaccga cgatttctga tgagcatatc tttgtaatgc
     2701 ctggaacaca taccaagttt atcaaactgg ataagaacgg taggattgtt aaatcaaaaa
     2761 ctgctaccac aggggagata ctttcattat tgaccaagaa atcgttgata gctacagatg
     2821 ttcatcatcg tttctatgat gaattagatg agtcatattt gttatcagga tttcattctg
     2881 ctaggagtaa cggtattggc agtgctgtat ttgatgtacg catattgggg caaactcata
     2941 atgcttcgcg gaatcagcga gcaaattatt tgttgggggc cgtactttct tcggatatcc
     3001 aactattaga aaatttttta gaacccaatg aaacagtagt actgactggc aaaaaggagc
     3061 ttagagaggc gatacatgtc attctcaatg acttagataa ttttagccat cctatcataa
     3121 tcattgaagc taacgattta gctggtcgag gtgcattatt ggctggaaaa aaaaggggat
     3181 tgttaagaaa agagggataa attaatggaa ttggaaaatt acccaaaagc gaccgctatc
     3241 ctgcgtggat atacttatga agaggcaatg ctagttattc gtgttctaag tgagtttaag
     3301 cattttatag gagtcgaagt tacaacaaat aatagtgacc acttaaaaat tatccatgat
     3361 ggaaaaaata gatttgggga taaaatttcg attggtgttg gaacagtcgt aactgtcgaa
     3421 caagcagagg aagcaataga agcgggtgct gagtttatgt taggcccgca aaaatttaat
     3481 gacaaaattt ttaaactagc taaaagaaag ggtgttctaa caattcctgg ggccatgtcg
     3541 cccacagaga tattcaaaat gtttgagatg ggtgctgata ttgttaaggt gttccccgcc
     3601 aactgtcttg gaccggaata tttcaatcaa gtgcaagccc ctttaggaag tttacctttg
     3661 atggctgtag gaggggtaga tcagactaat gcacaaaact atttgaacaa tggagcctct
     3721 tatgtaggaa ttggttcaaa attttttgaa aaaagtgctg ttcaccaact aaattacgag
     3781 aggctaatgg agttggctga atcttttata gatagtttaa gagttgaata gaacccattt
     3841 gcggaataca acttgtttta taatatggcg ttatctgtat aaaacatagt atcacagtga
     3901 atgagattga actggtagat tgatttttcg accagttctt tttgcgcgct ctgatgcttg
     3961 atatattccc aacgagataa aaaatccccc aagatactaa gatgaagcgt ttatccaacc
     4021 tcatacttag ataaaaagga ggaaatgttc tgaatgataa acaaaaatta gcgcgcacaa
     4081 tttggcgatg aaaaaatcat attgtattta cgtcaaaata tcaccatcaa attatttatg
     4141 gaaaacataa taggcataaa cccgattgct cggctactat gtggacacaa ttatagtttt
     4201 aaagataagt ttcaattact tattttacac ctcttcttta gggataaaac ttttcctaac
     4261 gatcaatttt gcgccgatta atgttttctt tgatatgtcc cgcgaatata ccagttgatc
     4321 acttaataaa tctacacagg ttttagctat ctcttcgata tctatcttaa aagttgtaag
     4381 tggtggtgca acgaattttg cgatgtcgtc atcattaata cttattactg ccatatcttt
     4441 agggatgtta atacccaatt catggcagcc ctgaagaacg ccggcagcta tagtgtcaga
     4501 tggtatgaaa catgcctcgg gcatatcttc atttaactca gctttcattt taagagttaa
     4561 ttgataccct tcgtcaacag taaatgatcc ttgggagaaa atatactttt cattgagtag
     4621 tccgctcttt tctaaatgat atcggaaggc atattcacgg ctatcaatct cttctttacc
     4681 cgtttctagg ttaaagaaat ttcctccaat aaatccaatt tttgtgaaac cttcattaat
     4741 aaagtagtta attgcttgtc tggccatttc gtggaaatca ggttctacag tatcgaagtg
     4801 ttcaggtaat gggtttattc ctcggattac ccccttatac cctttttgat ttaagtagta
     4861 caattccttt tttgtcaatt gtcctattgc gataaatcca gtaatatcgt caggaatgct
     4921 ttttacacca tcgtttttag agatgaaaat caaatctaga ttagcttttt tactataatt
     4981 tttcaaatca tctttgacat gttgatagta gacatccttt tttaactgtt cctctgagat
     5041 ccaaaaaaga atggcaatct tgtacagagt agtcttaatt tttgtcagat catatcctaa
     5101 agatttggct gtaacgatta ttttgttttt agtatcagat gtaatagaga gtgactcatc
     5161 acctttaaaa agtcttgata tagtagccgt tgagtaacca gatttttttg caatatctct
     5221 aatagtaacc attgttcatc ctcctaggga tataataatc cttttctttg ttaaagtaaa
     5281 tcgaaactgc tcttttagta acttaaatta ctttttctag caggaaacga aactctgata
     5341 tcagcagaga gcctaatcca ttaacagaga agattgaatc gataatggat agccacttgg
     5401 agaatgatta gtaggtggga ttgattttag tgggaatcag tccgttttct tgtttcgtgt
     5461 aaattaaatt agtaaaaaga taaatttatt ttacgaaaaa acgtttacaa aacggttttt
     5521 gaatggtata tttattttac atcaagggat ataagtgctt gtatatcgca ataaaataga
     5581 tattcgaggt cggtttttcg ttgtgtaaaa aaatttactt atacatgtta aaattatgct
     5641 gaggtgattt atggattatt ggcatattga tcaaactaat tttcaaggag agattaaaat
     5701 gaattataaa actttaccag aagactttat tatgggagga gctacggcag cttatcaagc
     5761 agaaggctct acaaaagaag gtggaaaagg gcaagtagcg tgggatactt tccttgtaga
     5821 aaagggacgc tatactgctg atccagctag tgatttttat aatcaatatc cagttgatgc
     5881 tgaattatgc aaaaaattta aaattgatag tattaggatg tctattgcat ggagccgtat
     5941 ttttccaaaa ggctatgggg aagtgaacca aacaggagtg gaatattatc ataaggtatt
     6001 tgctgaattg aataagcatg gtattattcc ttttgtaact cttcatcatt ttgatacccc
     6061 taaagaacta tttgataatg gagatttttt aaatcgagaa aatgttgaac atttcgtaaa
     6121 ctatgcacag ttctgtttcg atgaattttc tgaggttcat tattggagta catttaatga
     6181 gatttatcca gttgcttcaa atcaatattt gatcggatcg ttccctccag aagttcaatt
     6241 tgatatagag aagactgtaa cttgtttaca caacatgatg tatgcgcacg caaagacagt
     6301 aaacattttt aaagatggtg gatataaagg ggaaattggt gttgttcact cgctagagac
     6361 aaaatatcca gcaagtgaca aagaagaaga taagcatgct gcgaaattag atgatgcgtt
     6421 atcaattaag ttcttattag atgctactta tttagggtat tactcagatg aaacaatggc
     6481 acatattaat gagattttag cagcaaatgg gcaatctgca gatattgatt ctaatgattt
     6541 tagagagatg aaaaaagcag caaatcgaaa tgattttctt ggtatcaata actatggtag
     6601 ccattgggtt aaagagtaca aaggagaaag cacacttcac tacaacacta ccggagaaaa
     6661 aggtagccaa gtctattgca ttaaagggat tggcgagaga atcgtgcgtg aggatcttcc
     6721 gaaaaccgat tgggattgga tcatttatcc aaaagggtta tatgatttac ttgtacgaat
     6781 ccaagacgaa tatccaaatt ataataaaat atacattact gaaaacgggc tagggtataa
     6841 ggataatttt gaagatggga ttattctaga tgatgatcga atcgattatt tacgccagca
     6901 ttttaatgcg atttccgatg ctatcaaaat gggagttaat gtaaaggggt atttcatttg
     6961 gtcattaatg gatgttttct cttgggttaa tggatacact aagcgttatg gactattcta
     7021 tgtagatttc gatacacaaa aaagatatcc gaaagagtct gcatattggt ataaatttgt
     7081 tagcgaaaca aaaacgataa tataaaaata gttaggaggg caaggaaatg gataggaaag
     7141 aattgcaatt attaggattt gaaattgttg cttatgcagg agatgccaga agttcattat
     7201 taacagtgtt gaaggaagtg agaaaaggta attttgataa tgttgaacga ttattagcgg
     7261 atgctgatga aaatttaacc ttagcgcata actcacaaac gaaatgttta gctgaagaag
     7321 cgtcagggaa cgaaatggaa gtaggcgtaa tttttattca tgggcaagac catttaatga
     7381 caacgattct attaagagaa cttatcaatg attttgttga attgtacaaa gaaaaatttg
     7441 ctaaagcata ggagaagaaa aatgaatacg attattaagc aaattgagaa gggaaaaccg
     7501 ttttttgaaa aaatctcacg taatatttat ttaggggcaa ttcgcgatgg ctttttaact
     7561 gctatgccag ctattctatt ttcaagtatt tttattatga ttgcggctgt tccagaagta
     7621 tttaacgtga cgttaccaga ggcattctcg acgtggcttt ggaaagttta tggttattca
     7681 atgggattag ttggtctttt ggttgctgct acaacagctc gatgtttagc taattcaatg
     7741 aaccgtcaat tatctgattc aggtaagcag attaatgaag tttctgttat gttagcgtca
     7801 atttgtggtt ttgtaatgat ggcagctgat caaattgatg gtgggatagc tactgattat
     7861 ttagggacaa agggattatt agcagctttc gtttctgcgt ttgttactgt aaatgtgtat
     7921 aaattctgtg ttaaaagaga tttgacgatc cgtatgccaa aagaagttcc cggaacaatc
     7981 acacagatgt ttagagatat tatccccttt tcaattgcag tatttattgc cgttttgatt
     8041 gatacgggag ttcgtcaatt ttttggaaca tcatttgcag caggtgtaat tcaattattg
     8101 cagccattat ttggtgctgc tgatggatat gtcggtattg caatcatttg gggagccatg
     8161 gcaatgttct ggtttgttgg tgttcatgga ccatcgattg ttgaaccagc gattgctgca
     8221 attatttatg cgaacgtaga aactaacttt gaattattta aaaacggtgc acaagcctca
     8281 aaagtattaa cagttggtct aggaaacttt gttggaacga tgggtggtac tggagcgaca
     8341 ctagttgttc cttttctgtt catgttgttc gctaaatcaa aacaattgaa agcagttggt
     8401 aaagcttcat ttattccagt ttcgtttgcg gtaaatgaac cgttactatt tgctactcct
     8461 attattttga atccgtactt tctaattcca tttttattag caccaatcgc taacgtatgg
     8521 atattcaaac tttttgtcga tgtcttgggg atgaatagct ttatatccgt attgccttgg
     8581 gcgacgcccg caccgattgg cttggtttta ggaaccgggt ttagtgtgtt ggcgattgta
     8641 ttagcggtag tattgattgt tgtcgatgcg attatttatt taccttttgt taaggcctat
     8701 gattctgaat tagtagaaca agagttaaaa aacattgctg cagaagaagt aaaagaagaa
     8761 ttggtcgaag aaatccaaga agttggtgca actgcggcag ttatagttga tgaagcaaaa
     8821 gcatcggttg gtgaaggaaa gcgcgtttta gtactttgtg ctggtgccgg aacgagtgca
     8881 atgttggcta atgcattaga agagggcgca aaagagacag gtgttaatct ttctgctaaa
     8941 gcaggagctt atggttctca ttatgatatg atgaaaaatt ttgatttaat cgttctagca
     9001 cctcaagtga attcctattt ggatgatctc cgtaaagatg cagacaaatt agggataaaa
     9061 gtaattgcaa ctaaaggtgc agaatatatc aatttaacac gtgatcctaa aggagcagtt
     9121 gattttgtat tgaagcaatt ttagagcttg cttagattaa taaagcgcta gccaacttag
     9181 ctagcgtttt atcttaaaca caatggtaag cgctatcttt ttttgctgtt taaatttcgg
     9241 gtattctttt tgaggacgtc gattgtaaaa ttaagctaga caactaaaaa gatcatttgt
     9301 gctacactca aaatagttcc gaccaaagaa ttaataagga gtgagtacaa atgacctaca
     9361 cccatcttac aacagacgaa ctagtaatca tagagtctta tttcaatatc gagaaacctg
     9421 tcgctcttgt cgcacaaagt ttaaatcgct ctagacaaac catttataat gtttattcgt
     9481 ttctcaaaca aggaaaaaaa gtgctagatt attaccgtca atacaaacaa aataaatctc
     9541 gttgtggacg acgttcaacc gttttatctg atgaacaatc aacatatgtt caagaaaagg
     9601 tagctcaagg gtggtcaccc gatgtgatta tcggccgtgg cgagtttcca attgattgtt
     9661 ctgttcgtac actctatcgg atgtttaaaa aaggcctttt tgacacacag tcgttaccta
     9721 tgaaggggaa acgtaaaccg aataatcatc aagaaaagcg tggaaaacag gcctttcgca
     9781 gaacgattca tgaacggaac agtctctatc cacacctgac taaagaattt ggtcatctcg
     9841 aaggcgacac cattgtggga gttaaacaca agagcgctgt tattacatta attgagtgtt
     9901 tatccaaggt tattattact ttgaaaccga caggcagacg agccgaagat atcgaaaaca
     9961 ggttaaatga ttggttcaaa tccatgccta aacacttgtt taaatccatg acatttgatt
    10021 gtggaaaaga attttccaac tggcgatcta taagtaactc gaacgatatt gccatctttt
    10081 tcgcagatcc aggaacacct tcgcaaagag ggctaaatga gcactcaaac ggcttgctta
    10141 gacgagatgg cttacctaaa acaatggact ttagggacac ggatgaaacc tttattcaat
    10201 ccgttgcctc gaaaagaaac catattccaa gaaaatcatt aaattatcga acaccattgg
    10261 aagtattttt gagctgcata gataaagaca tattgtctag cttaatttga caaatcagaa
    10321 aagaaaaaat gtatcaagtt tttgaagaaa tgggttatcc aattaaaacg gtcaccagaa
    10381 aactagaagt aatcaaagcg gatgatacga tcagcgattt gttagatgtg gaagaaggag
    10441 atccaatgtt ctatttccat acgcagggtt tttcgctaga acgtctgccc gttgagtatt
    10501 cgatttcgaa atatcgagga gacattaact actttgtttt tgaacttgca caataacttc
    10561 agattaaata aaatgattta ttaaagataa aagtcgaatg aacaaggctg tcactatgac
    10621 agtcatgctc gttcggtttt attttttaga atagcagctt gcaaattctg aaaaattttg
    10681 ctttccttcc tgcagaaggc ttcttaagaa aacttgttct agcacttttc ttaagaattt
    10741 gatagtctta aaaagaaaag aggcgatgaa atgttaaaaa cggatcgatt ccaagcgatc
    10801 atgtcgttat tagaggttaa cggtacagta cgagtcagcg atattatgga gaagttttcg
    10861 gtttcggata tgacagtccg acgtgatttg gacgaaatgg agaaacaagg attattagaa
    10921 cgcgtccatg gcggagcgaa attgaaggat ttttatcggc atgtggagct ttctcataga
    10981 gaaaaacaga ttatgctgca agaagaaaag cagcggattg tggaaaaggc gaatgaaatg
    11041 atcaatgatg gtgatacgat atttcttgga ccaggaacta caatcgagct catgtcaaaa
    11101 atcattcaag gggattcact gcggattgtt acaaactgtt tgcctgtttt tgaagaatta
    11161 aataagcgaa aagggaatcg aaaaatctat ctattaggtg gcgagatgcg ggaaacgact
    11221 caatgctttg ttggtgaaat cacgaataaa tcgctacagg atatgaattt tcataaagca
    11281 tttttcagct gtaatgcttt aaatgaacag aaaattatga cttcgacttt tgaagagggc
    11341 caaactcaac agatcgctct gaataattct gttgaacgct ttttattgat tgatcattcg
    11401 aaaattggga aaagagattt ttcagtatat tataatctga atgatgtaac agtagttata
    11461 acggatgatg atgaacaaaa gcactatgaa aaaatcgaaa aagaagaaaa atatgttgtg
    11521 taaatgagaa actgccaaac tctagataat tagaacttgg tagttttttg gtagccttga
    11581 atttaagcga attatgttat ttttagggtg catcattact aattcctccg aatacttgaa
    11641 tacaccattt gaaaaaagat agtcgatttt tttgggatgt tatgtttatg tgaaggaaaa
    11701 aatagcagta tcaatcaccg ctttattaag gaggaaaagg gatatcaaaa caaccatgga
    11761 cactaagtca gctgaagctc tttgacatga aacgagttag atcagaaaaa gcaatgatga
    11821 aatcgcacgc ataaccgcgg gatgcgaagc gattcaggaa aaaagaaatc aaggaattcg
    11881 caattaaaca acaaaaagtc aaaaagcaca aaacaaacaa gaacacaaaa agaatcgttg
    11941 aggaatacca acaaaggcaa gcttaaagga gttaaaaaaa gcataaacgt tgataatttc
    12001 tttattgggt gtggcaagag atgggctatg ctttttgaaa tggattttac atctatttat
    12061 tttttatagg taaaataata ccccgaagtc taaagacatt cggggtgttt ttagcttatt
    12121 tagcttcggc tgcataagtc atattatgcg ccgttgccgg agatgcattc tcttcttttt
    12181 cagctgcgta tgcagcgttg cgttttttca tttgacgagc gtaccaaatg aagattaaaa
    12241 ggtatgcacc taatgctaag gcagcgtata tcacaaattc gatttgtcct tgagaagcat
    12301 taccgactaa ataacctagg aatttttcaa tcgggccttc catcgttgta tgagagatca
    12361 tggcggaccc gttcaagccg gctggaaagg ctccgactgc tttagctgtt tgagtaacga
    12421 acggggcgat caaggtgccg gaccataaga ataatggtaa ttcgatcgcg ccgattacga
    12481 tcatacggat taattttcca cgagttacga ccaatagtgc tggggtaaca cccattgcga
    12541 tgattccgcc tagtggcaat aatttatttc ctggtaagat gatggcttct agcaacatga
    12601 ttggtgctaa tacgttagcg gcagcccaga tttcagcgcg gcctgctatg aaaggccagt
    12661 ctaaacctat gttgatggta cgtcctttta gtcgtttatt ggcaaaatcg gtaatccctt
    12721 gtgataacgg ttctacggct gcgatgaacc aagcgcctat caaagagaac aattccaaac
    12781 agacggcagc ggtaaaggct agcgagaaaa tttgcgttgg tgtttgtcct gctagtaatc
    12841 caacaaaaat ccccaaataa attccaatcg cgaattttga tccccagaag ccaattttac
    12901 tattcaattt ggcagcatcg aaatcatatt tatccaacca agggaagatt ttgtcgaaaa
    12961 ttttatcgaa aaccataata atcggattca tcatgtagtt catatgagtc gtggtcatcg
    13021 ggttgctgtc tggcgcattt aacaagtcat tgaaggttgg tttcattaag tcggagttcc
    13081 aaatttttaa tacaccaatg aaaataacta atgcagaagc aataaacaga ttagcaccgc
    13141 agaagatcgc gaacaaacca acaattgcta aatgccaaat atcgaaaata tccacatcta
    13201 atgtgttggt ttttttcatt gctaacatga caatattgac gatcaccata attagtaaaa
    13261 aataaagcgt gtatggcgac ccccatgtga tggttgctag tggggcccaa ccgacatctg
    13321 taatgtttaa tgaaatacct gtgcgttcaa caaaagctgt catagcgtct gaaaaagcag
    13381 tagttaaaat tccaataata gctccgatcc cagtcagggc gatccctaat ttgagcccgc
    13441 cttcaagagc gcgtgacggt tttactttaa aaaataaagc aataacagtt aatacgatgg
    13501 tcattaacgg tgccgcacct aaattaatta ggggggtaaa tactttattg gcaatatcaa
    13561 taattgtatt catatgcttt tcctttcttt agtcctattt gtttaatgat tggattgcgc
    13621 tttccatact ttggtaaaca ggctcagcca tagcaggaat acgataaaga atagcacctg
    13681 catcaacgac agggatgtta atgtcaaaac ccaagtcggt gttggcaatt tgtgcgaaaa
    13741 tgtcataatg agacagcatt tcttcattga tatctttgat cataacggcg tcacaggtga
    13801 cttgatagcc acgatttttc aattcagttt ccaaagcgct tttgatttga tggcttgaat
    13861 taacgcctgc tccacatgct gctaaaattt tgatcataat aattctcccc ttaaaataag
    13921 tttatttttt atcctgcggt taggcagaga cttctatata taaaaatgtt cttctaaaaa
    13981 atgataaatc gcttctgtgt cctctaattt gaaaaacgaa aacagttttt cttcgtcaac
    14041 agaattaatg aaatccatga tattagccaa catgccagcc tgtgcttcac cattttcgtt
    14101 caagatcatg aaaagaaatg aagcggaaat ctgatcgctt ggcgagatca tgttgtagaa
    14161 agggatttca ttttttactt tgattggaat gatacgggtg gttcgcacaa actcactttc
    14221 ggtatgaggg atagcgatat ctggcaatat tttagagaca ggtgagagat ctaatcccgt
    14281 cggataatta cgctcccgtt ctaaaaggtt ctccaaaaaa tcttcggtta ccaattcttt
    14341 ctttaacaga tcttgataga cttcctcgaa cacttcttcc tgcgactgct tgtcagaaac
    14401 atagacagtg tctttgaaaa agaattcatt cacacaaaac agctccttta ttagttcgtt
    14461 tatgtttatt tatctgttta caagttgagt ataaccgctt acaaaattat tgtcaacgca
    14521 taaacgaaaa taaacgaaca atatgtgttg aaaaatgttc gtaaatgttt tattataagg
    14581 tcgtggaggt acagaatatg ctgaaaacag aacgacagcg ttcgatctta gcgatgtgtg
    14641 atcgctatgg gacgataaca gtcaaattta ttcaggaagt actgaatgtt tcagatatga
    14701 cgatccgccg agatctagag gaactcgcgc agaagaaaaa gcttttacgc gttcatggcg
    14761 gtgcacaaaa aatcgattat ctggaaatgt cgacttctat agaagcaaat gagctttctc
    14821 atactgaaaa aaagaagctg catacaaaag agaaggaata catcgctaaa aatgcggcag
    14881 ctcatatcaa tcaagaagac gacacgattt ttcttggatc gggtacaacg atcgaattaa
    14941 tgacacgata catcaagccg tcatctctcc gaatcgttac caatagtctg ccggttttca
    15001 atctattaag tgaaataaaa agatttgaac tgtatttgat cggtgggcta tatcgggaaa
    15061 agactggagc ctttgtcggt tcaattgcca atgaagctgt tcaaaaaatc ggtattaaga
    15121 aggcttttgt cggagtgaat ggattgaagg gttcggaggt ttcgaatttc agtattgaag
    15181 aaggtacctt gcaaaaaatt gttttagata atgcggcaga aaaatgtttg gtttcagatg
    15241 caaacaaatt cgaccatagc gatttttata atttctatga tttgcgcaag atcgacaaat
    15301 tatttacgga ttctactctt tcagccgagc tgaagagtta ttatcagcaa ttcactaaaa
    15361 tcattcagta aaaaatagga ggaaacaaaa atgcgtgtag taattggttc agacagtgac
    15421 ggcatggaat taaaggaatt aatcaagaaa aaattgatca aagaaggtat tacagtagta
    15481 gataagagtg aaacggcttc agaagatttt gtggaatcaa ctttggcgat cgcaaatgat
    15541 ctgaatgaaa acgaaggtag tttaggaatc gcggttgatg gctacggcgc tggcagcttt
    15601 atcacggcaa caaaggttaa aggaatggta gcagcagaag tttcggatga gcgcagtgcg
    15661 tatatgaccc gtgaacataa taattctcgg atgatcacac ttggatcaaa aattgttggc
    15721 gatgagttgg cgttgaatat tgttaaggaa tttctacaag caaattatga tggcggtcgt
    15781 catcaagtac gtgtcgacat gttaaataaa atggcgtaat taggaaggat gaatgaaatg
    15841 aaaatcgcaa ttggctgtga ccacatcgtc acagatacaa aaatggcagt atcagatttc
    15901 ttaaaatcaa aaggacatga agtgttggat atggggacct atgactttac cagaacccat
    15961 tatccgatct acggaaaaaa agtcggagag gccgtgacta gcggagaagc agatctagga
    16021 gtttgtttgt gtggaacagg tgttgggatt aacaacgctg tcaataaagt acctggtatc
    16081 cgcagtgcgc tggttcgcga tatgacgact gctatctatg cgaaggaaca actaaatgcc
    16141 aatgtgatcg gctttggcgc tcggattacg ggagaatttt tgatctgtga catattagag
    16201 gccttcatca atgccgatta tcaagaaact gaagaaaaca aaaaattgat cgccaaaatc
    16261 gatcacgtcg aaaaagccag tgacaagcag tctgatccgc atttcttcga tgaatttatc
    16321 gagaaatggg atcgtggcga ataccacgat taagcgggtg gacaaatgat tttaacaata
    16381 acgatgaatc catcgattga tatttcttat ccattagaaa ccttcaagct cgacacagtc
    16441 aatcgagtaa gaaatgttcg caaaacagct ggcggtaagg gcctaaatgt gacacgtatc
    16501 ttgaagcaat tagatacgga ggtgattgct agtggtttaa tcggcggttt tttaggtgaa
    16561 gagattaaaa aggacctgac tcaaaatgag attgctcatg actttttacc tatcagcgga
    16621 gagacacgta attgcatcgc tgttttacat gacggaaaac agacggaaat cctagaaaac
    16681 ggacctgtta ttactgaaca agaagcaagg gcgttcttgc aacatttcga aaaattagct
    16741 gttaaagccg aaatcatttc tttttcagga agcttgccag aaggattgcc tgctgatttt
    16801 tatcgacaaa tgctgcaagt ttgtcagcca aagcctgtcg ttttagattg ttcaggtaca
    16861 gcattaaggg aagtgttgcg aggcagtgta aagcctaagc taataaaacc caataccgaa
    16921 gagctggctg gtctgctagg acgagaaatc tcaacagaat tatcagattt aaaagccgcc
    16981 ttgtcagatt cgatgtttga tgaaattgaa tggatagtgg tttcaatggg gggcgacgga
    17041 gcctttgcca aacatcacga gactttttat tgcgtgacaa ttccaaagat tgatgtcgtc
    17101 aatccagttg gctctggtga tgcgaccgtt gccggattga ccgctgcgat tcaacaaggt
    17161 ctttcggatg aagccgtgtt aaaacagggt aatgttttag gaatgctgaa tgctcaggaa
    17221 gcgacgactg gctatgtcca attagccaat tatcaaaaac tatatgatca aatcttagtg
    17281 gagaaagtgt aggaggatac ggaaatgaac gaagaaaaac gtcaatatat caagcaacta
    17341 tgcaatgaag atggagtgat tggggcctta gcaattgatc aacgcggggc tttgaagaag
    17401 atgatcacaa aattcaaggg cagcgaagca gaagaatcag aaatcgttga atttaaagaa
    17461 attgtttctt cacaattaac gaaatatgcc tcatcgattt tattagatcc cgaatatggc
    17521 ttgccagcag ctgacgttag agcaaaaaat gccggcttgc tgttagctta tgaaaaaact
    17581 ggttacgatg cgtcaactcc cggccgttta ccagatttat tatcgatctg gtcagttaaa
    17641 cgtttaaaag aagcaggcgc cgatgcttgt aagttcctac tttactatga tgtcgatgaa
    17701 gcagaagaaa tcaataatca aaaacatgcc tttattgaac gaatcggctc agaatgtcag
    17761 gctgaaaact tacccttctt cttggagctt gtttcttatg acgcgaacat ctctgatgcg
    17821 acttcgaaag aatacgccat taagaaacct cataaagtca acgatatgat gaaggaattt
    17881 tctgatccac gttatggcgt agatgtgtta aaggtggaag tacccgtcaa tatgaattat
    17941 gtggaaggct atgggacaga cgaagtcgtg tacacaaagg cacaagcggc taacttcttc
    18001 aaggaacagg ctgaagccac taacctgcca tttattttcc taagcgccgg tgtaaaagca
    18061 gagttgttcc aagaaacact gcgcttcgcg aaaaatgccg gctcaacctt caatggtgta
    18121 ctttgcggcc gtgcgacttg ggcagatggt gtagaaagct atatcgttga tggaaaagaa
    18181 gcagcgatgg agtggatgaa tacgcaaggg cgtaaaaata ttgaagaatt aaatgccgta
    18241 ttgaaagaaa ctgctacacc ggtggaagtg ttaacaagct cactatcata agaaatcaga
    18301 ctgtgaagca caattgcttg cagtcttttt ttatacataa agcgtaaaat catgctgcat
    18361 tattagggga acgaattcta aaatagtaag tgagttaaaa cgaaggggtt tttctttaga
    18421 gagattttct tacatgtggt acttaatgac ttgatggcaa ttttcagtat tctaacgagg
    18481 cttattggtc ataaaccaac gaactttgaa aagtatatac aagaaaacca agcaaataga
    18541 aagtagtgag actggaggaa aggttccagt ctttttctat tctaggtatt ttcaaacagt
    18601 aaaatcattc ttaattatgt gttttttaac agaatgtatg aatttcttca aatcttcaca
    18661 aaaagaacgt ggactttgaa gaagagcgtg tactatgcta aaaagcataa gtgtaattac
    18721 taaatccgta tgaggagtga atatacatgc gtgtactggt ggttgaggac aatcgtgagc
    18781 tggttttatc cgtaaaaaag ggcctagagc aggagaatat ttctgtagat gtagcttatg
    18841 atggcgagtc aggagaagag aaggccttca tcaattcata cgatgggata ctactagatt
    18901 taaatctgcc taaaaaagat ggattatctg ttttacaaag tctccgtgct gaagaagtcg
    18961 aaagtccagt tatcattatt actgcacgtg atgagattga agaacgagca aaaggcttgg
    19021 attttggagc agatgattat ttagtcaaac cctttgagtt actagaatta aaagcacgaa
    19081 tacgcgcggt tattcgtcgt tatcatggac gtgcgctgcc gcagatttca attggtgctt
    19141 tgaagattga tccattaggt cgaagggtca gctatcaaaa gacagaggtg gtcctgaaac
    19201 ccaaggaatt tgatatctta ctgtgcatcg ctcagcgtca tccagcggtt gtttcgtctg
    19261 aggaaatttc tgaacatgtc tacgatgaag attttgatcc tttttcgtcg gttctgcgag
    19321 tgcatctggc tcgtctaaaa aagaaactgg ctgaagcagc tgaaaaagag gtcttaaaaa
    19381 ccattcgagc aaaggggtac cagctatgct attaaatttt aaaatgacgt taacgatgct
    19441 ggctttttca ctgttggtga caggcgtgat tttagtgagt ttcttctttc tgagaaataa
    19501 tttggaggga atcagtatcg catctacctt aggtgaagat gtttatttta tggaagaggg
    19561 taagacggtt caagcagaga cgcagatgga agcttcgaaa tcttccaaca atcaatttat
    19621 gactatttcg atgatagata aagcttacca ggacgaacta tttaaatatt taccagcgat
    19681 ggtgctggtt atttgttctg ccgtcatgtt attaacgttt attctttggt tggttttacg
    19741 caaaatttac agtaatcaaa tcttagcgat tacgcgtgat ttaacgttta ttgatcaagt
    19801 tcctaaaaat actgtgaagg acgaggcatt aaatgcggct tttaataagc taaaggataa
    19861 gttcgatggt catttggagg attatcgacg attaaatagt tatctgaccc acgagcagaa
    19921 aaatgccatc gctattttgc gtacgaatct ggaaatagaa cggcaacatg ccgatcaagg
    19981 aaatttaatg cttttagatc ggatgaccga cagtattgac gatattttga cattatccaa
    20041 taactcagag gatcttagca cggaagtcgt agacgtttca ctgatctgtg cggaagtttg
    20101 tgatgcctac aaaatgaatt atccgaatct tttgtttgcg tttactgaag atcaaccaac
    20161 cctgattcat ggacgagatc gttggattta tcgggcggtt tcgaatttag ttgacaatgc
    20221 aatcaaatat ggtgaaggaa aactggtaat tgtcaccatt tcaaaccaaa agggtagcgt
    20281 gattattgaa gtaaaagatc agggaattgg cattcctcag gagaaacagg catcaatttt
    20341 ttctcatcag taccgagtgc atgggctcaa gcaggatggc ttacctaaaa caatggactt
    20401 tagggacacg gatgaaacct ttattcaatc cgttgcctcg aaaagaaacc atatt
//
LOCUS       DAZKPE010000046        20285 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000046 DAZKPE010000000
VERSION     DAZKPE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.046"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            140..460
                     /locus_tag="ACG930_001911"
     CDS             140..460
                     /locus_tag="ACG930_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519067.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="ACG930_001912"
     CDS             912..1112
                     /locus_tag="ACG930_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0519068.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="ACG930_001913"
     CDS             1259..4048
                     /locus_tag="ACG930_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFQ0519069.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="ACG930_001914"
     CDS             4095..4622
                     /locus_tag="ACG930_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFQ0519070.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="ACG930_001915"
     CDS             4643..5833
                     /locus_tag="ACG930_001915"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0519071.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="ACG930_001916"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="ACG930_001916"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFQ0519072.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8224..8898
                     /locus_tag="ACG930_001917"
     CDS             8224..8898
                     /locus_tag="ACG930_001917"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFQ0519073.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8895..9236
                     /locus_tag="ACG930_001918"
     CDS             8895..9236
                     /locus_tag="ACG930_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519074.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9266..9625
                     /locus_tag="ACG930_001919"
     CDS             9266..9625
                     /locus_tag="ACG930_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFQ0519075.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9885..10007
                     /locus_tag="ACG930_001920"
     CDS             9885..10007
                     /locus_tag="ACG930_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519076.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEKKKKE"
     gene            10149..12230
                     /locus_tag="ACG930_001921"
     CDS             10149..12230
                     /locus_tag="ACG930_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0519077.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12541..14007
                     /locus_tag="ACG930_001922"
     CDS             12541..14007
                     /locus_tag="ACG930_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFQ0519078.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14622..15161
                     /locus_tag="ACG930_001923"
     CDS             14622..15161
                     /locus_tag="ACG930_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFQ0519079.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15235..15675
                     /locus_tag="ACG930_001924"
     CDS             15235..15675
                     /locus_tag="ACG930_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFQ0519080.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15688..15897
                     /gene="copZ"
                     /locus_tag="ACG930_001925"
     CDS             15688..15897
                     /gene="copZ"
                     /locus_tag="ACG930_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFQ0519081.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15897..18083
                     /locus_tag="ACG930_001926"
     CDS             15897..18083
                     /locus_tag="ACG930_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0519082.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18103..20274
                     /gene="copB"
                     /locus_tag="ACG930_001927"
     CDS             18103..20274
                     /gene="copB"
                     /locus_tag="ACG930_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFQ0519083.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6777 a         3528 c         4407 g         5573 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaacggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactg caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ctatcatcat
     5341 caacggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtgggaaa
     5401 tcctgtgatc atcaatggaa tgatcgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggcgag caagatacag tggaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatattcg cttgtggcag aactgccggg
     5581 tgtttctctt gaaaagccac aaggagcttt ttatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctaaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcgc atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatat gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttatgatga
     6721 tgcgatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtgat
     6901 ctgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacagactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggtgatg aaaaagctgt tctgcatcaa
     7201 gtaattagaa cagccaagca aaaacagctg ttcatgtttt tgaattggcg ggacttatta
     7261 ccgcagatgt aagcttttga ataccgttta gtggagaggt tgtgaaaaag ctgtttagtt
     7321 tcgagtatta agaaaaattt tgtggaaatg gctttccaca tttttgcata aatttggctt
     7381 aataccgaga aactggcttt tgaacaccgt ttaaggaaga ggttgtgcgc ctgccgttca
     7441 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatg actattgtga
     7501 cttgtgaccg aggagttggc cggagagcac cgtttattct aaaaaagaac tgcgaactct
     7561 cgcagttctt tttttaaaat acgggataaa ggaagtttcc agcagacaag agaagaaagc
     7621 aaaagaaatt gctatttgat tcacaaggtt ctataacgaa atcgcaatca atcaaacatt
     7681 tacaaagaag gtaattcaaa tggaaatctg atttgatgat gcttctgctg ttgaaataaa
     7741 gcagcatcta gcacctgaaa acaaactaat agtaacattc gaagatggag taggtccgta
     7801 ttttcagcat gcaataatcc atatgtaagt tcaattcacc cttgaaatca tcggaccaga
     7861 taaagttatg accaatctat cccaagcaat ctagaagaga tattagtaaa gggacattta
     7921 ctagaagtct tagatgagcc tataaatata tgttctgatg gcgtcatcag tggtctgatt
     7981 gacggaagct taggtgtgat cgatctctct ggaccaaaca acgaaggaat caaggggaat
     8041 ccggcacgtt aagaaaaaaa tagcataaaa aactagacac ttgatgagcg ttcattcaat
     8101 tgtttgaagg gactaggctg gtgtcatttt ttatacatat attttctctt tcgtcttgat
     8161 agggcttatg ggataatata aggaagaaaa tcatcgtttt attcaaaaag gagtttttga
     8221 caaatgaaaa aacgtatatt atttatcggt gatagcatta cagacgcagg aagagaccga
     8281 gcagaagcaa ctgatctagg taaaggttat ccacttttga ttgccggaaa actaatctcc
     8341 caatatccaa cgatggaatt tgaatgcatg aaccgtggga taggaggaga caaaattgca
     8401 gatctgcaag tacgctggca agaagattgt ttagctttac aacctgacta tgtatcgatt
     8461 ttgatcggaa tcaatgatac ctggcataat actagcgatc aggctatatt cggaactgag
     8521 aaatctgctc agcaatttga atccgtttat cgaaaattac taaatgaact tcaaacagtg
     8581 ggaatctgca acatcatctt gatggagccg tttgtacttc ctataaccga cgaccgtcat
     8641 ggctggcgta aagacttaga ccctaaaatc caaattgttc gtaaacttgc taaggaatat
     8701 ggcgcattgc tggttccttt agatggtata ttcaatgctt tagggattgt ttatggtttt
     8761 tcgaaatata caagagaaga tggggtccac ccaacgattg gcggacatga gatcattgca
     8821 caaagctgga tagatgcaat tgccgcagtc gattttttta gtggagataa aaatgagcga
     8881 aagaaaagtg agaaatgatg gaaatacggt gggcagtaaa agaagatcta cctcaaatca
     8941 atcagctgat tactgatcat ccagaatcat tcgtaaaagc aaaaacggca gctgacctaa
     9001 atgataagaa taaactattg ctcgttgctg taacaaaaga aaaacggatt atcggatttg
     9061 cgcaagcgga cgtgcaacag tcagaagaac gattggatca gcgaccatca ggaaaactaa
     9121 tccaacacac attagtaaca aaagaaaata cggaagaaat ccaaaaaaaa tttgcagaat
     9181 atttgatact ggaagctaaa aaaagaagaa taaaatcatt ttttgcccag ttttaatcaa
     9241 aaacagtaat agaaggagaa atacaatgag ttgtttagga aatgtcatct ggtttatatt
     9301 cggcggacta atcggtggtc ttagctggtt agcagcgggg atactttggt gtatcacgat
     9361 cataggtatc ccaatcggta tgcaatgttt taagatcgcc tccctttctt ttgcgccttt
     9421 tggcaaagaa gtaatttatc accagtctgg catgtcattg attgttaata tcatctggct
     9481 gatcgtttca ggcctaccaa ttgctctcgc acatgtcgtc agcggcatcc ttctatgtat
     9541 cacgatcata gggatacctt ttgccaagca atctttcaaa cttgctcgat tggcgttgat
     9601 gccattcggt gcagaaattg tataaaagag aataataaag gttagataaa gcatagagtc
     9661 aggtgggata catgtatttc acctgactct atgcgttctc ctgtataagt tcttccatgt
     9721 gacttttacg tcttttattt atatggggtt actgtttatg gaaagttgaa ataattttca
     9781 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9841 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
     9901 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
     9961 gttggataag agcagtggca atgatcgaaa agaaaaagaa agaataagcc aaaacatctg
    10021 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10081 tgaataaccg ttcatttata attagttatg aagagatatt catatgttga ggcgaggagg
    10141 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10201 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10261 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaataaaaa
    10321 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10381 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10441 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10501 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10561 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10621 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10681 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10741 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10801 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10861 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    10921 ttggtgaaac agtattaagt ggatttatca ataaaaataa accattttta gttcaagtag
    10981 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11041 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11101 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11161 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11221 tgatctccgt accccttagt ttctttggcg gtatcggagg agcaagtaaa atcggtgtat
    11281 tagtaaaagg ttcaaattac ttggagttgc ttgcacaaac tgagacagtg gtattcgata
    11341 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11401 caaagatatt catgcaatat gttgcgagtg cagaacagtt ttctacacat ccgattgctc
    11461 aatctgtttt agaaggctac gcaggtccgc ttttaccaac agctaatatc caagaatttg
    11521 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11581 tgatggaaag atttgaaatc tcttttcctt caagtcaaga aatcggtaca ttgctttatc
    11641 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11701 ccgtagacgc attggttcaa ttaaaaaagg ctggtgtgaa gaacacagtc atgttgacgg
    11761 gcgattcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11821 gcgaattgct tccagaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    11881 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    11941 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12001 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12061 aaatcgtcaa acagaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12121 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12181 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga
    12241 ggacgaatga acgtcctctt ttttttatat ccttttctta atgaaaaatg taaagaaaat
    12301 agataggatt ataaaataac taatgttttt aattttgcag aaaattcaaa atagcttgaa
    12361 attcaataag gtaaatgaaa taaaagaaaa taacttattt ttttgatgga aaaaatatga
    12421 aaaaacgatg tgtattaaat aaaagaatac acacataaaa taacactgtc ttgtaagttt
    12481 gttaaaaatt gaatatgatt acatctggat aacaaatttt tatcataaag gagagaacga
    12541 atgaacaaca aacaattacg ctggtttact gttgcgttaa ttgcatttaa catggtttgg
    12601 ggcatgggga atgtagttaa taactatgct cagcaaggag tatcagttgt cacctcttgg
    12661 ctattgattt tggccattta ttttattcca tacgcattga tcgttggaca attagggtca
    12721 gccttcaagg atagtaaagg aggcgtcagt tcatgggtcg aaaatacgac atctaataaa
    12781 cgactggcat actatgccgc ttggacttac tgggtcgtcc atattcctta tttggcacaa
    12841 aagcctcaag caatcctgat tgctggcggt tgggcagtcc aaggaaatgg aaatatcgta
    12901 aatacgatgt cagtacaaat ggtagcagtt atttcactta ttatatttct tgccttttta
    12961 tatttatcaa caaaaggact ttctactttg aaagtgattg gcggactggc cggaacagcg
    13021 atgttcgtca tgtcgatctt atttattctt ttagctgtaa cggcaccgtt catcaatcca
    13081 acgatggaat ttgccacacc acatatgaat caagtgaaaa catatattcc aacatttgat
    13141 ttcagttatt tcacaaccgt ttcgatgcta gtatttgcag ttggaggagc ggaaaaaata
    13201 tccccttatg tcaactctac aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc
    13261 ttagcagcaa tggtagggat ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt
    13321 gctagcgata atattcctaa agacttgatg gcaaatgggg catacagtgc ttttcaaatt
    13381 ttaggtaatt actatggtat cggtaactca ttgatgatca tttacgcatt gacaaacatg
    13441 attggacaaa tctccgcatt agccttttca attgatgcac cactaaaaat cttgttagca
    13501 gatgcggatc cagaatttgt accaaactgg ctacgtaaac gtaatcgtaa aggtacattg
    13561 gtgaatggtt atcttctgac aggtatacta gtaggaatca ttattttgtt gccgatcttt
    13621 ggtatcaaag atatgaatga attagtaaaa tggttgacga acttgaactc agttgtcatg
    13681 ccaatgcgtt acctatgggt gttcttggca tatatgatgt tgaataaagc ttataagaaa
    13741 ttcaattctg aatataaatt tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg
    13801 tgctttgcct tcactgcgtt tgcatgtatc ctaggaatgg tgccaaaagt agattatact
    13861 gctgatccta aagcatggtg gttccaatta ttcacgaata tcatcacacc aattgtcttg
    13921 atcttattag gtatgatctt gccagcaatt gctcgtcgag acaaaaacaa agaaatcact
    13981 gaaccagaaa cagtggttca gccttaaaat agaaatactt gttacaagag gttgtgacag
    14041 aagtggtcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    14101 aagtttcggc ttgtttttcg cagaagctac ttctggaaca ccgtgaatca gaggttgtga
    14161 aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagcccc tcatattttt
    14221 cgttttgctg ggcttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggta
    14281 gtgagcctgc cgtttaactc cgagtcacaa ggagcaattt caaaaaacaa cttctcatgt
    14341 ttgttgacta ttgtgccttg tgaccgaggt gttggcagga gaacaccgtt taaggaagag
    14401 gttgtaaaat cagcgatttg acctgagtat tagaggaaca aacgaaaaaa tagctcctca
    14461 tattttgccg ttttttgagt taatgctgaa ggtcagctga ttgaacacca tttattcgaa
    14521 acaagggact ttgacacgac ttttgtcaca gtcccttgtt tttttgcggc gttataagtg
    14581 gtatgatcga accaaattcc aaagagaagt gagggagaag aatgaagatc atcgtgattg
    14641 gacaaagtgg gtcgggaaaa tcgaccctcg caaggaagat caaagaaatc accgactttc
    14701 cgctactgcc gctagacctt ttatggcata caacagacta cagtattcag gcaaaaaagt
    14761 ggtttttgca agaacagcaa tcgtttatgg tatctaatcc gtcatggatt gttgaaggaa
    14821 attatacttc tacattagag gaaaggatta aagaagcaga taagatcatt tggcttaaag
    14881 tgccgcgtta tctcgccatc taccgagtag tttggcgttc tctaaaaaga aagataaaca
    14941 aaaaatctcg gccagatatg cctgaatcat tttcagagaa actaaacagg gaatacttag
    15001 aatttttatc ttttatctgg cattttgaag aaaacaatga accgaaaata cagcagctga
    15061 tccaagtagc taatgcaaga aataaactga tcatccttaa aacaagacga gagaaacaag
    15121 aatttttaac taaattgaaa atagagagca aaaataattg acagtttttg tttacaagcg
    15181 taatctgtat tcataagcta atgattacat ttgtaaacga aaggtgtgaa ataaatggaa
    15241 aaagtcaaaa cgccagtaaa gatcagtgat tcagagtggg agatcatgcg tgttatttgg
    15301 acacttggac agacgacagc ccaagaaatc acgcagatct tagctgattc gatggattgg
    15361 aaaccagcaa cgatcaaaac tttgctggga cgtttggtaa aaaaagaagt gatctggaca
    15421 gaacaagaag gaaaaaaatt catttatcat ccagctgtct cggagatgga aacagttcgc
    15481 agtgcgacgg aaaatctttt ttcccatatc tgtgcaaaaa ggattggaga gacgattgcg
    15541 gatctagtag aagaagccac tttgactcaa gaagatatca atgagatttt gaaacaactg
    15601 gaacaaaagc aaccagtaga tacgatcgaa tgtaactgta tcccaggtca atgtgaatgt
    15661 aaacaacatc aataggagga agaaaaaatg aaacaacaat tttcaatcga aggtatgagc
    15721 tgcaatcatt gtgcagcaag agtagaagaa acagtaagcg cacttgacgg cgtgcaaaaa
    15781 gtgaaagtaa atttgaaaaa agcaaacggt acggtcaagt ttgatgaaac aaaagttcaa
    15841 tccgaaaaga tttgtcaagc aatcaatgga ttgggttata aagcagaggt gatttgatgg
    15901 caacagcaga aaccaaaatg gatacgttcg tcattacagg tatgacttgt gcaaattgtt
    15961 ctgctaggat cgaaaaagag ctgaacggac aacctggtgt ggtcaatgcc acagtcaact
    16021 tggccactga aaaagcaagt gtcaaatatg aagggacgac cactgaaaaa ttaatccaaa
    16081 gcgtagaaaa catcggttat ggtgcaattt tgtacgatga agcccacaaa caaaaaattg
    16141 cagaagaaaa gcaagcgtat ttgaaaaaaa tgctattcga tcttatattg agtacggttt
    16201 tgactttgcc gttgatgttg tcaatgattg ctatgatgtt aggaagccat gcggcgattg
    16261 ttcacttttt tcattttcca atcgtccagt tagtgctgtc tgctcctgtc caattttatg
    16321 tcggtgctcg tttttataaa ggtgcgtacc atgcaatcaa gacgaaagca ccaaatatgg
    16381 atgtattggt agcaattgga acatcggctg cctttgcatt gagcatttac aacggatttt
    16441 tccgtggaca cccccaagat ctttattttg aaagcagcag tatgatcatc acgctgattt
    16501 tgctcggcaa atatttggaa catacagcaa aaacgaaaac aggtaatgca atcaaacaat
    16561 tgatgtctct tcaaacaaaa accgcccaag tgataagaaa cgggaaagaa gaaacgttag
    16621 cgattgaaga agtagtcgtt ggtgatcaac tagtcatccg tcctggtgag cagattccag
    16681 cagatggtcg aattatttca ggaagcagtg cgatagatga aagtatgctt actggtgaaa
    16741 atcttcctgt agaaaagaat ccggatgaca cgctttttgg cgggacaatc aatacgaatg
    16801 gtctgctaca catggaagtc acacaagtcg gcaagcagac agtattagcg caaatcattc
    16861 aaatggtgga agatgctcaa gggagcaaag ccccaatcca aaaaatcgca gatcggatct
    16921 cagggatttt tgttccgatc gtattagtca tcgcgtttat cacgctcata gctacaggtt
    16981 tgatcactgg tgattggcaa ctcgcattga tccatagtgt ctctgtatta gtcattgcgt
    17041 gtccatgtgc attaggttta gcgaccccaa cagctattat ggtaggaacg ggtgttggtg
    17101 cacgaaatgg aattttaatt aaaggcggag aagcattaga agcagctgct cacttagaca
    17161 gcattgtttt ggataaaact ggaacgatta cagaaggaaa gcccaaagtt acagatctag
    17221 tcggttcaaa agaagtccta tctatttttt atactttaga acaagcttct gaacatccac
    17281 taggtaaagc aatcgtggaa tacggaaaac tgcaagaagc agcaacatac gatatgattg
    17341 attttacagc ccacccaggt gctgggatca gcggtacgat taatggagta cgctattttg
    17401 cgggtacacg taaacgatta attgaattga acctatcatt tgatgaatac caagaacacg
    17461 cgttagaatt agaacagcag ggaaaaacag tcatgttttt agctgatgaa aagcaagtga
    17521 tcgggtggat tgccgtggct gatcaaatca aactagaagc caaacaagca atcaagcagc
    17581 tccagaataa aggattagat gtttttatgc tgacaggaga caacaaactg gcagccgaaa
    17641 cgattggtaa acaagttggt attgatccaa agcatatctt tgctgaagta cttccagagg
    17701 ataaagcagc ctacgtagaa aaacttcaga aagatggcaa aaaagtcggt atggcaggcg
    17761 atggaatcaa tgatgcaccg gccttagcat tagctgatgt cggtatggca atgggaagtg
    17821 gaacggacat tgcgatggaa acagccgatg tgacgctgat gaatagcagt ttggcatcca
    17881 ttgcacaaac aatcgagttg tctaggttga cattgagaaa aatcaaacaa aatcttttct
    17941 gggcttttgt ctataatacg attggtattc cttttgccgc actaggcttt ttgaatccaa
    18001 tcattgcagg aggagcgatg gcgtttagtt ccgtcagtgt attgttgaac tccctgagct
    18061 taaatcgaca catgaaaaag taagagaagg gatggagtaa aaatgaatgg gaacgatatg
    18121 gagaaaaaac atgagcataa aaaagaagta gtaaacaaag aaagtacaga atctcatgaa
    18181 aaacagatgg agatgaaaca tgaccatagt cagatggatc attccatgca catgggacat
    18241 aaccatggag atatagcaaa cagcaaacaa atggaccatt cgatgcacat ggatcacgaa
    18301 cacggcggca tggatcattc catgcacatg gggaatttca aacaaaaatt ttggctatcg
    18361 cttatcctag ctatcccaat cattcttttt tcaccaatga tgggaatgga atttccattt
    18421 caagtaacgt ttcctggttc tgattggctc gtattgatct tagcaactat actatttatc
    18481 tatggcggtc agccattttt aagtggagct aagatggaat tgaaacaaaa aagtcctgct
    18541 atgatgacac tgatcgcgat ggggattaca gttgcatata tttatagtgt ctattcgttt
    18601 atcgcaaatc tgctcaatcc acatacacac gtcatggatt tcttctggga attggctact
    18661 ttgatcgtta ttatgctact aggtcactgg attgaaatga atgctgtgtc gaatgccagc
    18721 aatgctttac aaaaactagc agaattactg ccagaatcag tgaaacgctt gacgaaagat
    18781 ggaaaagaag agacagtttc attgaaagaa gtaaacgaag gtgatcgttt gatcgtccgg
    18841 tctggtgata aaatgccaac agacggtgta atcttgaaag gtgaaacaat tgttgacgaa
    18901 tcagctgtga ctggcgaatc aagaggaatc aaaaaacaag ccaatgacaa agtgattggc
    18961 ggttctatca atggggatgg aacgatcgaa atcgaagtaa ctggaactgg tgaaaatggt
    19021 tatctagcga aggttatgga aatggtgcga aaagcacaag gagaaaaatc caagctagag
    19081 tcattatctg acaaagtggc aaaatggctg ttttatgtcg cattaattgt gggtatcctg
    19141 gcattcatcg cctggttgtt cttgacagat cttcctaatg cattagaacg tatggtaaca
    19201 gtctttatca tcgcctgtcc tcatgctcta ggtttagcta tcccattagt tgttgctcgc
    19261 tccacatcaa tagcagctaa aaacggatta cttttgaaaa accgcaatgc actggagcaa
    19321 gccaatgatc tagatgtgat catgctggac aaaacaggaa cactaacaga aggaaaattt
    19381 actgtaacgg gtgtcgaagt acttgatgat gcgttcaata aaaatgaaat ccttcaatat
    19441 ctaggagcct tggaagcgaa tgccaatcat ccattggctg ttggcattat gaattatttg
    19501 aaagaacatg aaatcaagcc ttatcaagct gaaaatctaa aaaatctttc aggagtcggg
    19561 ctagaggcaa cagtcaaaaa acaacaagtg aaaatagtta atgaaaaaga agttgagcgt
    19621 ctcggattaa acgtagaaca agcattattg aaaccttacc aagaacaagg aaataccatc
    19681 agcttcctga ttttagaaaa tcatctagct gcaatcgttg ctttaggtga cgtagtaaaa
    19741 acagaagcaa aagaatttat ccgaacattg aaagaaagaa aaatcactcc tgtcatgctt
    19801 actggtgaca ataaaaacgc tgcccaagca gtagcagatt atttagggat cgaagaatat
    19861 tatggcggtt tattaccaga tgataaagaa gctgttgtcc agaaatacct tgaccaaggg
    19921 aaaaaagtaa tcatggtggg tgatgggatc aatgatgcgc caagtttagc ccgtgcttca
    19981 atcgggatgg caatcggtgc agggacagat atcgcaatcg attctgcgga tgtcgtattg
    20041 acaaacagcg atccaaaaga tattttgcat tttcttgatc tagccaagca aacgcgaaag
    20101 aaaatgatcc agaacctctg gtggggggca ggttacaata ttcttgcaat tccgctagca
    20161 gccggaattc ttgcgccaat tggtatcata ttaagtccag cagttggtgc tgtcttgatg
    20221 tcgttaagta cggtagttgt agctctaaat gctttgacat tgaaaatcaa ataataatga
    20281 aaaaa
//
LOCUS       DAZKPE010000047        19507 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000047 DAZKPE010000000
VERSION     DAZKPE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.047"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACG930_001928"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACG930_001928"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFQ0519084.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="ACG930_001929"
     CDS             complement(1173..1868)
                     /locus_tag="ACG930_001929"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFQ0519085.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="ACG930_001930"
     CDS             complement(1881..2597)
                     /locus_tag="ACG930_001930"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFQ0519086.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="ACG930_001931"
     CDS             2927..3532
                     /locus_tag="ACG930_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFQ0519087.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="ACG930_001932"
     CDS             3857..4180
                     /locus_tag="ACG930_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFQ0519088.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="ACG930_001933"
     CDS             4362..5732
                     /locus_tag="ACG930_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFQ0519089.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="ACG930_001934"
     CDS             complement(5862..7163)
                     /locus_tag="ACG930_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFQ0519090.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="ACG930_001935"
     CDS             complement(7393..9384)
                     /locus_tag="ACG930_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFQ0519091.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="ACG930_001936"
     CDS             complement(9528..9794)
                     /locus_tag="ACG930_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0519092.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACG930_001937"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACG930_001937"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFQ0519093.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACG930_001938"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACG930_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFQ0519094.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /gene="def"
                     /locus_tag="ACG930_001939"
     CDS             13138..13701
                     /gene="def"
                     /locus_tag="ACG930_001939"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFQ0519095.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="ACG930_001940"
     CDS             complement(13954..14475)
                     /locus_tag="ACG930_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFQ0519096.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="ACG930_001941"
     CDS             complement(14478..15320)
                     /locus_tag="ACG930_001941"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFQ0519097.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="ACG930_001942"
     CDS             complement(15313..16038)
                     /locus_tag="ACG930_001942"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFQ0519098.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="ACG930_001943"
     CDS             16214..16510
                     /locus_tag="ACG930_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519099.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16766..16940
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17078..18670
                     /locus_tag="ACG930_001944"
     CDS             17078..18670
                     /locus_tag="ACG930_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0519100.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="ACG930_001945"
     CDS             18683..19423
                     /locus_tag="ACG930_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519101.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DAZKPE010000048        19290 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000048 DAZKPE010000000
VERSION     DAZKPE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.048"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            188..967
                     /locus_tag="ACG930_001946"
     CDS             188..967
                     /locus_tag="ACG930_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519102.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1013..1957
                     /locus_tag="ACG930_001947"
     CDS             1013..1957
                     /locus_tag="ACG930_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFQ0519103.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1973..2752
                     /locus_tag="ACG930_001948"
     CDS             1973..2752
                     /locus_tag="ACG930_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFQ0519104.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2764..3462
                     /locus_tag="ACG930_001949"
     CDS             2764..3462
                     /locus_tag="ACG930_001949"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFQ0519105.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3490..4254
                     /locus_tag="ACG930_001950"
     CDS             3490..4254
                     /locus_tag="ACG930_001950"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFQ0519106.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4299..4988
                     /locus_tag="ACG930_001951"
     CDS             4299..4988
                     /locus_tag="ACG930_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0519107.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6215..6895
                     /locus_tag="ACG930_001952"
     CDS             6215..6895
                     /locus_tag="ACG930_001952"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFQ0519108.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            6924..8237
                     /locus_tag="ACG930_001953"
     CDS             6924..8237
                     /locus_tag="ACG930_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HFQ0519109.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9067..9810
                     /locus_tag="ACG930_001954"
     CDS             9067..9810
                     /locus_tag="ACG930_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HFQ0519110.1"
                     /translation="MSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVVTPNVDHIV
                     QLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLCKMAAEKGY
                     TMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDSQIKRANPD
                     MLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSDYGFEWLFR
                     ITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9837..10838
                     /locus_tag="ACG930_001955"
     CDS             9837..10838
                     /locus_tag="ACG930_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HFQ0519111.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10861..12147
                     /locus_tag="ACG930_001956"
     CDS             10861..12147
                     /locus_tag="ACG930_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HFQ0519112.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12181..12834
                     /locus_tag="ACG930_001957"
     CDS             12181..12834
                     /locus_tag="ACG930_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0519113.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12867..14072
                     /locus_tag="ACG930_001958"
     CDS             12867..14072
                     /locus_tag="ACG930_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0519114.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14148..15527
                     /locus_tag="ACG930_001959"
     CDS             14148..15527
                     /locus_tag="ACG930_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519115.1"
                     /translation="MEIRISYYFRKLLLFYVCVIVAAMSYHLTGNSNVASLIAVVGVV
                     YAIVKACNNEYLAIWVMFVLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKV
                     KARSRYGIVYSVMLIFILIACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSE
                     RITKNEFIDLVCKFTRWTMCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILY
                     FFINLYAVIYKREGYNSTNKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLK
                     PSKIIRFGILGIALIACLVSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLE
                     GHELFGVGIPNNHDARAVEYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYI
                     VALAISIIDAGFRRDKSVAAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISA
                     FNDEFIYIE"
     gene            15544..16674
                     /locus_tag="ACG930_001960"
     CDS             15544..16674
                     /locus_tag="ACG930_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WavE lipopolysaccharide synthesis family
                     protein"
                     /protein_id="HFQ0519116.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16700..17785
                     /locus_tag="ACG930_001961"
     CDS             16700..17785
                     /locus_tag="ACG930_001961"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HFQ0519117.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17808..18623
                     /locus_tag="ACG930_001962"
     CDS             17808..18623
                     /locus_tag="ACG930_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519118.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18607..>19290
                     /locus_tag="ACG930_001963"
     CDS             18607..>19290
                     /locus_tag="ACG930_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HFQ0519119.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALL"
BASE COUNT         6475 a         2852 c         4239 g         5724 t
ORIGIN      
        1 acttttaaat cataaattgc cctagtcaag aaaacagttt gtggtatgat tatataggga
       61 aaacttgttt acaaatattt ctgtgaatat attagtttaa ttatgttttt taaaataaaa
      121 agctgtcatt tttatgtaag tgaattatat cttaatttat ctatcatcaa tacttaggag
      181 tgaatctatg gaaaagccat tcgtcaagtc attgactgct gtggcggtag gtgcaggtgc
      241 tattgcgatc tgtttgtttg gttaccatat caataatcag cggcaacatc agcaacggat
      301 caattatgca gaatctgcca tcaccaatca aaaagacacc ttgacttctt tatcaaaaga
      361 agtagacaag ctgtatagta caaaagaaaa aatttttcta aaccctgaaa taacagaaga
      421 aacaatcaca agtttgtcaa ataagctatc ctatgtcaaa ctttcagcag atgattacga
      481 catcaaagaa tcagaattgc ctaaagaagc tgttgcaatc caagatgaga agaaagcaat
      541 cgtgacacag ttagatagtg cagaatcaaa actgaagatc cagacagctg tcaacgattt
      601 gtttactaaa aatgtatcaa actggcagca agctgtagac gatgtcatca tcaaagaaaa
      661 ggtgacaagt gcagatgtcg ctcgtgtacg tgaaaatatg agctttttta aagatagtcc
      721 ttggaaaacg gttgttatgc aatatttagg attcgctgat actcagatcg cgcaagtcac
      781 gcaactagat cagttattcg atacgatgtt gaaggatggt caagtgactg ccaccgctac
      841 ttacgatcaa tatttgacgg cgctcagtca aatagagcag atccggaatg aaaaaataag
      901 cgcagcatac gcaacaaaag cacaaactgt tgctcagcaa atgggctata gcaatataag
      961 ttattgacag ttaaaacgtt gattcaagca aggttagcaa acggaggaaa ctatggcaag
     1021 acgaagaaga aaatcaagag ggaaaaaaat atttctgatt attttagcag ttcttatcgt
     1081 attagtatta gcaattgtag gagtaggagc aaaattatat ctggatctct cacattctat
     1141 tgagaaaact tacgaatcag tggaacgaac ccaaggagaa cgaacgaaac cagttgatct
     1201 ggacaaacaa gaatctttct ctgttctatt gatggggatt gatactggag atttaggtcg
     1261 ggtcgatcaa ggaagatcag atacgatgat ggttgccata gtcagtcctg aagacaaaca
     1321 gacaacgatc gtcagcattc ctcgtgatac gtatgtcgac atcgtaggtc gtgacacaaa
     1381 agacaagatc aaccacgctt acgcattcgg cggagctgcc atggcgatgg ataccgtaca
     1441 aaaatatgta gacatcccaa tcgatcacta tgtctctatc aatatgaaag ggctaaagga
     1501 acttgttgat gcagttggtg gtatcgaagt caataatgac ctcactttct cacaagatgg
     1561 ctatgacttt acaatcggta aaatcacatt gaacggggat caggcattat cttattctcg
     1621 tatgcgttat gaagatccaa atggtgacta tggtagacaa gagcgtcaaa gaaagatcgt
     1681 agaaggtgta gcaaaaaaag tattgagttt aaacggtgtc agcaactatc aatccgtttt
     1741 gaatgctcta gagtcgaata tgaaaacaga catgagcttt gatgaaatga aaaaaatcgc
     1801 tttagattat cgggaggcat ttggtacgat caagcaagat cagctgcaag gagaaggctt
     1861 tatgcaagat aatatctcct atcaaaaagt cagtgatcaa gaacttgatc gtgtaaaaaa
     1921 agaattaaaa gatcaaatga atctagagaa taaataggaa agtggagaaa aaatggaaga
     1981 gacaatcaac ttggaagaaa tttttgaaac attacgcaaa cacttggtaa caatcatcat
     2041 ctcaatgttt gctggcttgg ccatctcagg aatcgtaaca tttttcatct tgacaccaaa
     2101 atacagttca caagcacaat tgatcgtgac actgccacaa tcagacacag caaatgtcaa
     2161 tgatgtcaat acgaacctgc aaatgatcaa tacgtataaa gatatgatcg tcagtgattt
     2221 agtactaaat gaagtcaaag atcgtttaga aacagaagac aatgtgaaaa tgactgctgg
     2281 acaaatcaaa gatgcgatct ccgtcaatca gtcacaaaat tcacaaatgt tctcgatcca
     2341 ggcaataagc acgaatgcag tgactgctca acagatcgct aacacaactt cacaagtttt
     2401 ccaagagaac gcaaaagacg tgatgaatgt cgataaaatc tcgattattt caggtgcagt
     2461 tgccaatacg acacctgttt cgccaaataa taaattgaat ctagtgattg gcttagtatt
     2521 aggaatgatg gtaggcgtag gtctggcatt cttattcgaa ttacttgatc ggacagtgaa
     2581 agatgaaaaa tatgtgacgg atgcattagg attcccaatc ttaggaacag ttccagaaat
     2641 gtcagcgaaa gaattgaacg ctggtatccg taaaaaagga acagctcctg cacgaccaaa
     2701 agctacaaac gataaaacag ccccatcacg cagaagccgc tcaagagtct aggaggaaga
     2761 aaaatggcac gaacacagaa acaaaaagca gcacaaactc atgcagtcag tttgatcaca
     2821 ttaacaaacc catcttcacc aatcgccgaa caatatcgta cgatccggac gaatatccag
     2881 tttgcctccg cagctggtca gcaaatcaaa acgattgtcg tgacttcatc aggtcctgga
     2941 gaaggaaaat ccaccactgc agcaaacatt gcagtcgttt ttgctaaatc cggtcaacga
     3001 gttctactag tcgatgcaga tttacgtaaa cccgtcgtct ataagacatt ccagctgaac
     3061 aatgccaggg gattaagtac agcacttagt tcatcaggaa gtgtagcaga tgtaatccaa
     3121 cgaacgccag tcgagaactt gtcgattttg cctagtggac ctaagccacc caacccatca
     3181 gaattgttaa gttcgccaag aatggatcag atcctagacg aagcaagaca gttatttgac
     3241 gtggtgatat tcgatatgcc accagtagta gccgtaacag atgcacagat catgtcttca
     3301 aaaacggatg gcactttatt ggtcgtacgt gaaaatacat cacgtaaaga atcattgaat
     3361 aaagcaaaag aactgctaga gatggtacaa gcacgagttt taggtgttgt atacaacgga
     3421 gcagaacata gcaaagatgc tggttattac tacggaaatt aaggaataag aagagaggag
     3481 acaagagaaa tgatcgatct acattgccat atcctaccag gaatcgatga cggggcagaa
     3541 aacttagaag caagtattgc aatggctgaa aaagcgattc agcaaggcat cacgcatatt
     3601 ttatgcacac cacaccacaa taatggaaaa tacagcaatg aaaaatcaca agtcatttct
     3661 ctagtcgctt cgttacaagc cgaattagag aaaagacagt tgcctttgac gttattggaa
     3721 ggacaagaag tacgtattac cggaacgctc atcgaagaca tccaccgaga tgaaatttta
     3781 tttacagatt tagatgatac atatcttctg atcgaatttc cgacactgga agtgccgtta
     3841 tatgcagaat ggcttttttt tgagttgtta gaactaggaa agacaccagt gatcgtccat
     3901 ccagaacgca acgcgcattt tcgagaagac ccaaatcatt tgcttccgtt cctagatatg
     3961 ggatgtttgg cccaaattac tgcgccaagt tatgttggtg tatttggcaa agacattcag
     4021 aaaacagcca aaacaatggt caaacataat ctcgtgcaga tggctgcttc tgatgcccat
     4081 ggggtctcta agcgtacctt ttacttaaaa gagtgctatg agcagattgc taaggacttt
     4141 ggtaaggaaa aagtagtaca gatgaaacaa gtcgcaaagg atctgatcaa cggggatgaa
     4201 atcagttatc cagtctatga agaggtaaaa aagaagaagt ttggtttatt ttagttcttt
     4261 attcgtagat aaaaaggaaa tgaggagaga gggaaagtat ggaaagtgaa gatttattat
     4321 ctcgtattag tgaagtacat cctaatcaag tttggttgga taaagaaaaa gttgaaaaac
     4381 gatatatcta tttatttttt aaaagaatga ttgatattgt aggaagcatt attggtttga
     4441 ttttagcttc tcctttgatg ttctatgtag cttatcgaat cagaaaagaa gagccaggaa
     4501 gtccgatatt tttttgccat acacgtgttg gtaaaaatgg aaaaacattc aaaatgtata
     4561 aattccgttc gatgtgttta gatgctgaag aaaaattgga agaattactt gatcaaaatg
     4621 aaatagaagg tgcaatgttc aagatgaaag aagatccccg tgtcactaaa ataggtaaaa
     4681 ttatccgtgc caaaagcatt gatgaattgc cacagctatg gaatgtttta aaaggcgata
     4741 tgagtctaat tggtccacgg ccacctttgg agagggaagt agctgagtac acgagatatg
     4801 atcttcaacg cttgtatgta aaacctggtt gttcaggttt gtggcaagtt agtgatagaa
     4861 ataatgttag tttccataaa atggttgagt tggatttaga gtatattagt catcgaagtt
     4921 taatgtacga cttgaggttg attttaaaaa cgttttatgt tattgtcaag cccaatggag
     4981 catattagtt agggatagaa tgatggattg ttaataaaaa agattacaca tgttcatatt
     5041 atcgtttcaa aagtaataac tgtaattatg gagggtttga atcacttgta gaaaatctaa
     5101 aaaaagaaag gtgaatgggg caattcagta tcattattct tatataaaag aaaatattcg
     5161 aaattttggg atgataccac tcttaaatat aatgatctaa atgctttaat attggtatat
     5221 ccgatatagg aactgacgag ctatttagta tgatacaaaa gtatattgat agccattaat
     5281 aaattttcca aaaaataatg acagcacacc aatttttata atttagcttg ttgaatcggt
     5341 atgttcatgg gacggttcaa aaaaagaatc gaaaaaataa acggtaaaat tttagtgaat
     5401 cctatgtaat aaaatttgga tagatggaaa aacagcacat aaggaggctg agtttgttgt
     5461 catttctgct cctacaaact atggtagtga atgtgttatt gaattagtga tgtctgttac
     5521 ttcagagaca ttggggataa ttaacttcac tatacctgta gggtatacaa aaaatggaag
     5581 aaaaaatatt atcaatagat tttatttagt tcagaatttt tacgtggaag taaattattg
     5641 atgataatct ttatccaatt agaattatta tcgtaggatg tgatgatgat agccgtgaag
     5701 ttgttcaagt atttaccaat gtctacaacg cagaaaatta gtttgggttt ttcggattgg
     5761 aaaatttcaa tgtataaaat cataaatttg ctgtaaatag acagtttggg gtagtaatag
     5821 cccaataaat tgttcgataa actcatcttt ggggtgagaa tagctcaatc attgaatttc
     5881 aaacctgcct ttggggtggg attagaggtc aatatgtacc tacataatac tttttggaaa
     5941 atgatggtgt tgagaatgta agtacatttc aatgtgaaat tctaatatag ccccaaacga
     6001 ggtcaataaa aatgacctaa actcgtattt ctcccctaaa cgaggaggag atagatatga
     6061 aaattgaatg tgccggcgtt ggagttggct gcttttagta ggaatgaaca tggttcgatg
     6121 agaactgttt cagatagagt ggtcgatgat cacaggcctt taagtcgttt acagatgatg
     6181 agacttgtaa aaatagaggg acgaatggaa aaagatgatt ggtatagaag aaaagaaagg
     6241 tgttcagaaa gacgtaacaa ttgataggga agagaatctt aggggacata gattctattg
     6301 gattggacgc agagcacaag atatcttctt ctcggctcta gctttgattg cattgagccc
     6361 tgtgatgcta attacagcgc tcgccattgt gattgacgat cccggtggca gcccgatttt
     6421 tgtgcaggat agagttggaa gaaatggaaa gctgttcaag ttttataaat tccgatctat
     6481 gtgtgtagat gctgaagcaa aattagaagc cttgttggca caaaacgaga tggatggtcc
     6541 ggtcttcaag attaaagatg acccaagaat cacgagagtt ggtaaattta ttcgaaagac
     6601 aagtatcgat gagttacctc agctctggaa cattcttaaa ggtgatatga gtattattgg
     6661 acccagacct gctttaccga gagaggtgga acaatacggt gactacgaaa ggcagcggtt
     6721 gttcgtacag cctggtctta gttgctattg gcagattgct ccacatcgta atgaactgtc
     6781 ctttgaagaa tgggtggaac ttgatgtgaa gtacatcaat gaaagaagct ttatcacgga
     6841 ctggaagatt atcttcttga ctttacaggc tgtattattt ggatatggtg aatgattata
     6901 tatagtatta ggagttgaaa tatgtgaata ttattttatt atcgggtggt agcggtaggc
     6961 ggttatggcc gctgtccaac gatattcgta gcaaacaatt catcaaactg tttaaggatg
     7021 aaaatggcga atatgaatct atgattcaaa gagtttatcg ccagattaca actgttgacc
     7081 cagatgcaaa ggtcactatt gcaacaagta agtctcaggc tagtgcaatc cataatcagt
     7141 tgggagataa ggcttcgatt tgtgtagaac cttgtcgtag agatactttc cctgcaattt
     7201 tgttagctgc agcatatctt cacgatgaac ttggcgtagg tgatgatgaa agtgttgcgg
     7261 tttgtcctgt tgatccttat gtagataatt cctattacga aggcgttgaa gcccttgaga
     7321 agttggtgca gcagaatacg gctaatttga ctttgatggg tattgcacct acatatccta
     7381 gtgaaaagta cggttatatc atccctgaaa gttctaacga agtaagtact gttaaggagt
     7441 ttaaggaaaa acctgacaaa gcaacggcag agaaatattt agctcagaat gctgtttgga
     7501 atgccggtgt atttgcgttc aaacttggtt acctgttgga aaaagctcac gcaatggtgg
     7561 attttgaaga ttatcgtgat ttgtattcca agtatgagac tttaaccaag atcagctttg
     7621 actatgctgt ggtcgaaaaa gaaacgagca ttcaagtgat gcgttataac ggggattgga
     7681 aagatgtcgg aacttggaac atgatggctg aagttatggc tgataatatt aaggggaaag
     7741 ctgtaatgga tgatacctgt gttaatactc agattgtgaa tgagttgaat attcctattc
     7801 ttgctatggg ctgcaaagat atggtaattg cagcaagtgg cgatggaatt ctgatttctg
     7861 ataaagagcg cagtggctat atgaagccgt atgttgagaa aatcagtacg gaagtaatgt
     7921 ttgcagaaaa atcctggggt acatataccg ttatggacgt tcaggaaggc tccatgactg
     7981 ttaaagtttc tatgcaggcc ggacagaagt tgagctacca ctaccacaat tctcgcgatg
     8041 aagtttggac tgttgtagca ggacagggta aagcgattgt agatggtatg aagcagattc
     8101 ttcgtgcggg tgatgtggtg actattgccg caggatgtaa acatacaatc gaagccgtga
     8161 caaatctgga tattatcgaa gttcagattg gtgaaactat tagcgtcgct gacaagtata
     8221 agagttcttt gaactaaaag ttcgcgaggt agttattatg gagatactaa aatttcaacc
     8281 cgtgggtaaa gattatcttt ggggtggaga acggtttaag acggaatttg gaaaaaattg
     8341 acttaacacc attaagctta tacgtgggaa tgcttagttc atctagacga taactacgta
     8401 cggaaatatc aaatatgaag gacagaatgg taaaaccgag ttgtggtatg tattggaagc
     8461 tacaccgggg ggtgatttat gcttttgagt acgatgtaac agaagaaatg ttacgaaatg
     8521 ctgtgatgga cagatcactt gggaaacatt tatataaaga agaagtacac aagggagatc
     8581 ttttttatgt cagttcatgg tattggcgct ggagtattag tggctgaaat acaggaaagc
     8641 tcaaatgtta cctatcgagt ttacgattat gatcgagtag ataagaatga taataagtga
     8701 gaattgtact ttgaaaaagc gattcaggta atgaatatgg aagccacttt gaaattggag
     8761 aaaagaaata agctcattca tttttatcct ggtggctctc gtgaaatact gtgtagatgt
     8821 aaatactgtg agcccgaaag aatccaagta aagacggggt tttcgttctc ggtaaaagag
     8881 gaatcttttc aagttctttt atgtatatcg ggggacggac aagttgagtc ggcaaatggt
     8941 gttatgaaac tcattagatt tgtaaaaaag atattgtatg tttttgccaa cgaatattgg
     9001 aagatgttaa gtgttgagcg atgcggactt actgaaaatt agatggggat agagggagga
     9061 tatctaatgt cacgaatgag atttatgaac acagaaattg acaatcttac aatgggtgaa
     9121 gtattggtag aggttgaaaa aatgattcaa gataggagat gcggatatgt tgtaactccg
     9181 aatgtggatc acattgttca gttggaaaca ggaaaagagt tgcaagatgt ttataaaaac
     9241 gcatctttaa ttttgacgga tggtaaacca ttgatttgga tttcaaagtt ttataagaca
     9301 ccaataaaag aaaaaatatc gggatccgat atattttctt tactgtgcaa gatggctgca
     9361 gaaaagggat acacaatgta ttttttaggt gcggcagagg gcgttgcggc taaagcggca
     9421 gataacctga tgaaaagatt tccgggatta aatgttgtag gaacatactc tcctccttat
     9481 gggttcgaaa aagacgaaga tgaaatgttt aaaattgatt cccaaattaa acgagcaaat
     9541 ccagatatgc ttattgtggg tttgggttgc cctaaacagg aaaaatttat gttttataac
     9601 tgtgatagat tgggagtacc tgtgtctttt ggtctaggag ctagtttgga ctttgaggca
     9661 gggaatgtta aaagagcacc aaaatggatg tcagattatg gatttgagtg gctgtttaga
     9721 attactcagg accctaaaag aatggcaaaa cgatatttgg ttgatgattt aaaaatcttt
     9781 aaattagcac taaaatatcg gaaaaaataa actatattca atgaggacaa tgaagtatga
     9841 ttattacaaa aacacctttt cgcatgtctt tttttggcgg cggaacggat atggaagatt
     9901 attttcgaga aaatggcggt gcagtgcttt ccactacttt tgataagtac tgttatgtga
     9961 atgtgcgtca tttgcctaga ttttttgatt acagcacaga gttatcatat tctcgtactg
    10021 agagagtaac aaatattgaa gatatcgagc atcctgcaat tcgtaatgcg atgaaaatgc
    10081 tagatatgca tgaaattcgc cttacatatg aagcagatct tcctgcacgt tctggtctgg
    10141 gtacatctag ttcttttgcc gtaggtatgt tgaatgcttt ctatgctttg aagggcaagt
    10201 acgctgacaa gaagaaactc gttgataaag caatttatct tgaaagagtc ctttgtaatg
    10261 aagcaggcgg atggcaagat cagattgcag cagcttatgg tggctttaac cgaatcaatt
    10321 tcaactcaga tggctatgaa gtattgccta ttattattac gcctgagcgt aaaaagcagc
    10381 ttaacaacaa cttgatgatg ttctttactg gattcaccag attttcctct gatgttcaga
    10441 aggcaaataa tgtcagcggc acagaggaca aaagagtaag actgaaaaaa atgtatgagc
    10501 ttgtggatga agcagaagcg gttctgactg ataagaacag agatctagat gatttcggca
    10561 gactgcttga tctcacttgg agattgaaaa aggctaccgg tggtgcgatt agcactggaa
    10621 gtatcgatga actttatgaa aagggcatgg ctgctggtgc attgggcggt aaacttctcg
    10681 gagcaggtgg cggcggtttc ttggtttttt atgttcagcc tgaaaaacaa aatgctgtgc
    10741 gttcggcaat gagtaatttg atgtatattc cgtttgaatt tgaaaacggt ggaacacagg
    10801 ttattcatta cacaccggaa atgtatattc caaaataaag aaatcagcga ggataagaat
    10861 atgaaagttg ttattatggc aggcggtaag ggaactcgca tctcatcggt tgcaagcgat
    10921 attccaaagc ccatgattaa aattgaaaac aaaccggtat tggagcacga aatcgaatgt
    10981 ctgagagacc agggattcac agatattatt cttaccgtta gccatcttgg cgatatcatt
    11041 atgaactatt ttggcgatgg ttctggaatt tcaccagtta ctggtcagcc ctttgacgtt
    11101 aaaattgaat actttttgga gaaagagcca ttaggaaatg ccggtgcatt gtttcgttta
    11161 aaggataatt tgaccgaaga cttcctcctg ctgaatgcag atgcgatgtt tgacgttgat
    11221 ttcaaccgat ttgtagcata tcaccgtgaa aagggtggct tggtgacatt gtttactcac
    11281 cctaacagtc atccatatga cagcggtcta atcattgcag ataaggatgg ctctgtagac
    11341 agatggcttg taaaggaaga ttcccgtcca acttattacc gtaacagagt aaatgcggga
    11401 ctccatgtga ttagtcctgc tgttcttgat gtcgagataa acacacctaa gattgacttg
    11461 gaccgtcagt tattaaagcc gttggcagga accggaaaaa tgttctgcta tgatagtcca
    11521 gaatacgtaa aagacatggg tacccctgat cgttattatg ctgtctgtga agattttaag
    11581 gctggaagag tgaagggcaa aaatcttcag aataagcaga aagctgtttt ccttgatcgt
    11641 gatggaacga ttaatcaata tgttggcttt ctgcgtcata ttgatgagtt cgaactaatc
    11701 aagggtactg aagatgcagt gaaaaagatc aatgccgctg gatatctggc tattgtaata
    11761 acgaatcagc cagtaattgc aagaggtgaa gtttcttttg aagaattgga agagatccat
    11821 aacaaaatgg agacacttct tggatataag ggcgcttatt tggatgcagt ttattattgc
    11881 ccgcatcatc cacataaggg atatgaggaa gagcgcccag agctaaaatt cgattgtgaa
    11941 tgcagaaagc caaagcccgg aatgttaatt caggcagcta cggacttcaa catagatttg
    12001 agtcagtctt ggatgattgg cgatggcgag aatgatatta aagcgggcca agccgccggc
    12061 tgtaagactg cattggttgg cgagagtgag tatggacagg atatgaccat agcaaccctg
    12121 agtgaatttg cagataagat ctgctaaggg atgttttatc acgaaaggag agtataaaca
    12181 atgatagaca atagattaca gaaacacatt gatttgctga ttaaacgcta tcccactctt
    12241 gaagtaatca agcaggatat tgttgacgga tacctgatta tggaggaatg ctatttaaat
    12301 gatggcaagc tgctgatagc aggaaatggc ggatctgctg ctgattccga gcatattgcg
    12361 ggtgagctga tgaaaagctt taagacgcct cgccctgtta gtagggaatt tgcagataaa
    12421 ttgattgcgg ttgatcctgt aaagggttct gaattagcta agaatcttga atatggtttg
    12481 atggcgattc ctctcgttgc tcatgaagcg ctttccactg cgtatattaa tgatgttgat
    12541 ggcctaggtg ttttcgcaca gcagttgttt ggatttggaa gacctggcga tgtattcctt
    12601 ggtatttcga catccggcaa tagcaaaaat gtgataaatg caactgttgt tgctagagct
    12661 cttggtatga aagtaattgg cttaactgga gccaaaggtg gagaacttgc aagggtagca
    12721 gatgtttgtg ttaaagctcc tgaaacagaa acatatatga ttcaggagta ccatttgcca
    12781 atttaccact gttggtgtct aatgttggaa gataaatttt ttgggaatag ataaaatatc
    12841 taagcccata ttgaaaggat aaaattatga atgtactatt tataacaact caatttccat
    12901 atcctctaga taatggcgga aaaattggtg cgtacaacgg tatcagtgtt ttatctagag
    12961 actacgatgt gacggtattg tctttcaccg aagaaccgca gtatgttgaa gaaggtgtca
    13021 gtttttttcg agagaaattt aatagtgtaa aatttgaaaa tcctgtgata catgatgtac
    13081 acataagaaa taatccaatg aaattggtag aagctttagc aatagggtat tgtctacgcc
    13141 aaccttatat agtttcaaag ttttatgatt caaaaatgct gcagttaata gatgaaaaat
    13201 tttctaacaa tgcatattgg gatatcattt ttattgacta tctgaatatg caaagttatg
    13261 gtcaatacat acgggagaag tataaaacac aatttggtaa gtatatctta aaagaccaca
    13321 acatagaata tgatttagtc ctacaggaag ctgaatcaag tcgaggttta aaaaagaagt
    13381 tgcttcagtt agagtataag cgtactcgaa agtatgaaga ggccgcagta aatagggccg
    13441 attattgctt tagtgtgtgt gatgcaaata cggaagtact gaaaaagatt aatgacaaca
    13501 gttatacgat gcttccaact tatgaaatgc ttacaggggt gaaaaaaaat atagagaaga
    13561 acacgatcct atatttgggt aacctttctt ggaaatccaa tatgcaagga ttagtttggt
    13621 ttttagagtc aatttatcca aatattcaac aaagaattcc ggatgtaaaa atcacaattg
    13681 tcggtagcgg gccagttgga acagatttta gtaaatattc aggcgtggat tatcgtgggt
    13741 atgtaaaaga tatttcacac atttatgacg atcaagcggt gctaattgta cctttgttag
    13801 aaggtagtgg tataagaata aaaatattag aagcgttcaa taatgaaatt gcagttgtat
    13861 ctacattagt tgggtgtgat acgattggcg caaaagatgg aagtgagtta tttatagcag
    13921 ataacgaaaa agattttgca acggctgtag ttagactgct tgaagacatg aatttgaatg
    13981 aaaaagtaag aaagaatgca aaattattct taaaagaaaa atactcctta acggctagac
    14041 aagatgagtt tagtgcgata attaacagct aatatatata taagcttatc tgatgatgat
    14101 ttataggagg aaatatatgg agatggctga gagaaaggaa aagaaacttg gaaataagaa
    14161 tatcatatta ttttagaaaa ctcctgttat tttatgtttg tgtgattgtt gcggctatga
    14221 gttaccacct tacaggcaat tccaatgtag cgtcattaat tgctgtagta ggagtagttt
    14281 atgctattgt aaaggcgtgt aataacgagt atctggctat atgggttatg tttgtattag
    14341 gttctgatat atgggggata gtgccatata ttaacattgg tagtggtgtg ttgcattggt
    14401 cagattttaa tgttatagta gcgatatttc tctgcttgag attcatcaaa gttaaagcta
    14461 ggagtagata cgggattgtc tatagtgtaa tgcttatatt tattttgatt gcatgtgtgc
    14521 aatcgcattc aatctatgga caagatgtac atacaacgct cttaacagct agagaattgc
    14581 tagttgtaat atccttttgg ccgatagtaa aaatagtata ttcagaaaga ataactaaaa
    14641 atgaattcat tgatttagtg tgtaaattca caagatggac aatgtgtata tattggtttg
    14701 aatggattct tgttaatatg ggattcaata taaccttttt acagacaggt gcacgctggg
    14761 gtactagaat ctatatagat ccgatattta tcattttata tttctttata aatctatatg
    14821 cggttatata taaaagagag ggctataata gtacaaataa aagtatatgg aattgcattt
    14881 ttagtttact gacatttgtt ataatctcgc aaggcagaag tggtatatta tatgtagtaa
    14941 taacctcggt tattatgctt ttaatttcgc ttaaaccatc caagattatt agatttggta
    15001 tattaggaat tgccttaatt gcatgtctag tgtctgtgac ccaaattaga gaggtcgtta
    15061 tatcttcgtt tgtagagtct cagagcagtg acacaggtaa tatcgcatat agaattgctg
    15121 aacaagatta ttttgaaaat aaattagaag gtcatgaact atttggagtt ggtataccaa
    15181 acaatcatga tgccagagct gtagaatatt caggcaaaac aatagatttt gagtctaaaa
    15241 aatataatcc ctattatctt gaggacttag gcgcttttga aattcgttat agatttggta
    15301 taattgcata tgcgttatat atagttgctt tagctataag tattatagat gccggatttc
    15361 gaagagacaa atcggtcgcc gcatttgcgg gtatggcatt catggtgttt atggcgctta
    15421 attttaattt gctagcgtat attacagcaa gaccgttcgg atttatgatt tctttaattt
    15481 tgatagaaat atcggcattc aatgatgaat tcatatatat tgaataggta agggagagca
    15541 cagatgaatt tagatcgatt aaagaaaata gcaaatatga tttcaccaat cataaaagtg
    15601 ataaatgcgc cgttagcgta ttttagtggg aaatcagatt atatggagaa gggaatattg
    15661 tggcctactg taacaaccta ctccaataac agtagaaaag tgattcaata tacaacttta
    15721 cctaaaaacg tagacaacat ggctcaaatg caatgggctg gggaaagttt tgaggacata
    15781 tgtatagttc ttcaaggtcc agtattagaa gacggtgatt ttacactaaa taccgttaaa
    15841 atgtataata aatactatcc taaagtaaaa cttgtagtgt ctacttggat aggattatct
    15901 gaagagacag aatgcaagtt gcgtgaagct ggtgcagatg ttgtattatg caagaaacct
    15961 gaaaaaacag gtgcgtacaa tattaatcta caacttactt ctgcatacga aggcgtaaaa
    16021 atggcgcaaa aactggggtg tagttatgcg ctgaaaacgc gaactgatca aagactatat
    16081 gcaaatgatg tactaaagta tttccaaaca ttattgaata tttttccatc ttcggactgt
    16141 aaagtagtga atcagcgatt aatatttacg acttatggaa aatcatttag atatcttccg
    16201 tttaatttat gtgatttttt ggtatacgga gaaactagtg aattattaaa attatatggt
    16261 attcaaagag ataaccgagc atcagacttt gggaaaatta tttatactga ggaaaaagag
    16321 tttaataaaa agatatttac actactagaa ggaaaacaag gtgtatctcc atatgatgtt
    16381 tttccagatt ttgatgcact atataaaaaa tatatgtttg cagaatacta tattgtgtat
    16441 aattatttcc tggaaaatat tgcaagtaat gaatcttatg gtgacttaat ggatgcctat
    16501 tatagttatt taaagaaata tgcagttgtt gctgattcag aaaaattgtt actatattgg
    16561 ccgaaatatg ttcaatataa tgttaagttc gaaaatgaac ttgatttcta tgcgaagttg
    16621 gattcaaaaa aatggatgga tatttatgct aattatacac cttttagtca gtgattatat
    16681 ggaaaggatg aggtgaataa tgaaaatcgg aatagtgact attgttaatg gggcaagttt
    16741 tggtaacaga ttacaaaatt atgcgactca aaaagtgttg gaaaataacg gctatacagt
    16801 tgagacaatt aataattgtt ttgacaaaga aagtacccta tccattgtta tcaaaaacgc
    16861 tatttataca ttatttaagt ttataccgca tttcaaaaag tcaaaaagta tctggaaaag
    16921 aatgtataca ttttatcaat gggacaagca gtatatagat tattctcatc gtaaaattga
    16981 tgcatctaaa aaaaacagct ttgtgagtat aaagaatgat tatgactatt tcttggttgg
    17041 tagcgatcaa atttggaatc caaaatatgc agccaataag ggatttgaac ttttatcatt
    17101 tgttccaaat gaaaaaagag tttcattatc aaccagtttg ggagttccat ctataccaag
    17161 tgatttagaa aaattatatg tgacagagtg gaataagttt aaatcaatat cggtacgtga
    17221 aaatcaagcg gcaaaaataa ttgaggactt gacaggcaca actgcggctg ttcacattga
    17281 cccaacttta atgttggagc gttcggaatg ggaagccttt caaaaaaaac cagacaatat
    17341 tgatgaaaat tacatcttgt cgtttttctt aactaatccg cctaaggata ctgttgatgt
    17401 attagataag gtcgctaaag atttgaaaat aggtgttctc accttagatg cgtcttggga
    17461 atattttcaa gatattactc cgaatcattt tgtttatttg atttcacatg caagaatgat
    17521 ttatacagat tcattccact gcacagtttt ttcattgcta tttggaaaac cggttgtggt
    17581 atttgaccgt tttgatagtg aaaaaatgaa ttctaggtta agtacattgt taaataaagt
    17641 aaataaagca catttttggg taggaaaaaa agctgatgaa gcaatgattc gtgcaatagc
    17701 atctgaacct gaatatgaca tagataagct gatggtatca gagagggaat gtgtaaaagc
    17761 ttatcttaaa gagtatttac agtaaaattt tgaaatggga tgaaaatatg gagcatttaa
    17821 gtgattgttt tggtaaaatg aagattgtta cgacttcatg cgcaagagaa tattttaagg
    17881 atgatttgga taaatcagag tattcatgtt ttgttgattc tcgagcagct atgtttttcg
    17941 caatgggaca agctttagct aaaagaagga atgtagttgt aatgcttgct gatgaattga
    18001 catcgtgtta tacggcacta acagaatgtg catttcaaca agttgattta attgtgtttg
    18061 cttttcagac agtcagacat gaaattgatt tagcatcttt gaagaattgt ggttgcaatc
    18121 taattaactg tagcgcccaa gacgatattg atagagttgt gtccaacact aaggggttaa
    18181 atcagacaac agtaattaaa atcaatatga attgtgagtc ggataaagat catatatgtg
    18241 agtatataga cctgccagac atacctgttt ttttccacgg tagcttatac tcacctgcaa
    18301 gtaaaaagaa atatgagcag tatggacagg tatcgaagta tttaggctat ctcgtggggg
    18361 gaaaagatgc aatactcata atttctcaca atgagttttt aaacgatatc agtgtatgga
    18421 ttaattatta ttcttttgga gaaattcaac ccaaaattat tatatttgac agtccgaatg
    18481 actatcaata taaatggctg tgtgacttag aatgcagtgt agctcattca accaaccgat
    18541 ttttgtctga ggatttagcc ttattgcaaa ataacggaat ttccattgtg ttaagaggtg
    18601 ataattatga tatcgtcagt taaaaatgtt caaattttag tatctttatt aaaacagcat
    18661 aatattaaag atatagttat ctcgccaggt agtagagatt ttcaattggt gcatagtgta
    18721 gaaacagaca gtttttttag aacctatacg gttgtagatg agcgcagtgc tgcctttttt
    18781 gctaatggac tttctatggc gattgataag cccgtgtgtg tatgttgtac ttcttcaact
    18841 gcctcttcaa attatatggc ggcagctaaa gatgcttttg ctaatggcat ccaacttgta
    18901 cttcttactg ctgatagaga ttaccgccgc ttatatcaga tggaagatca gatgattgat
    18961 caggtagata tgtatggggc ttatgtgcgt tctaacgttg atattcctat tgttaaggat
    19021 tctgatgatg aatggtatgc taccagaaaa ataaatgaag caatattgga gttaaatcat
    19081 ggcgttaagg gtcccgtgca gattaattat caattaatgg atttaagtgc gccgtttgtt
    19141 gagaccatgc cagagtatcg taaaattaca agatatcaag aggatgattt actgtcatca
    19201 gtagagattt ttaaacagaa actattatca aaaaagagaa taatggtttt atgtggacag
    19261 caggaagaaa ataatttaag tgccttattg
//
LOCUS       DAZKPE010000049        18806 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000049 DAZKPE010000000
VERSION     DAZKPE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.049"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            45..1412
                     /gene="nhaC"
                     /locus_tag="ACG930_001964"
     CDS             45..1412
                     /gene="nhaC"
                     /locus_tag="ACG930_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFQ0519120.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1693..2712)
                     /locus_tag="ACG930_001965"
     CDS             complement(1693..2712)
                     /locus_tag="ACG930_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0519121.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2734..3741)
                     /locus_tag="ACG930_001966"
     CDS             complement(2734..3741)
                     /locus_tag="ACG930_001966"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0519122.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3734..4399)
                     /gene="pgmB"
                     /locus_tag="ACG930_001967"
     CDS             complement(3734..4399)
                     /gene="pgmB"
                     /locus_tag="ACG930_001967"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFQ0519123.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4392..6686)
                     /locus_tag="ACG930_001968"
     CDS             complement(4392..6686)
                     /locus_tag="ACG930_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFQ0519124.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6946..9111
                     /locus_tag="ACG930_001969"
     CDS             6946..9111
                     /locus_tag="ACG930_001969"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFQ0519125.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9415..10248
                     /locus_tag="ACG930_001970"
     CDS             9415..10248
                     /locus_tag="ACG930_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFQ0519126.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10350..12050)
                     /locus_tag="ACG930_001971"
     CDS             complement(10350..12050)
                     /locus_tag="ACG930_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519127.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12557..13717
                     /locus_tag="ACG930_001972"
     CDS             12557..13717
                     /locus_tag="ACG930_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0519128.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13733..14176
                     /locus_tag="ACG930_001973"
     CDS             13733..14176
                     /locus_tag="ACG930_001973"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0519129.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14659..15189)
                     /locus_tag="ACG930_001974"
     CDS             complement(14659..15189)
                     /locus_tag="ACG930_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFQ0519130.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15294..15845
                     /locus_tag="ACG930_001975"
     CDS             15294..15845
                     /locus_tag="ACG930_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0519131.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15998..16471)
                     /locus_tag="ACG930_001976"
     CDS             complement(15998..16471)
                     /locus_tag="ACG930_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0519132.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16609..18081
                     /locus_tag="ACG930_001977"
     CDS             16609..18081
                     /locus_tag="ACG930_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFQ0519133.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVPMKAGDNA"
     gene            18078..18788
                     /locus_tag="ACG930_001978"
     CDS             18078..18788
                     /locus_tag="ACG930_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFQ0519134.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5760 a         3400 c         3884 g         5762 t
ORIGIN      
        1 ttttttcatg gcagggcctt ttcatttgaa ataggagatc gacgatgaat aaaaatattt
       61 ctttaaaaga aagtatcgct gtattgatcg tgttgttggc actcctagga gtactgatca
      121 tcggattcca gctctcgcca catatcccga tccttgcagc tttcatgtgt ttgttgtttt
      181 atggcagatt taaaaagttc acatgggatg agatccatga cgggatcatc aaaggaatca
      241 ctccagggat cattccaatc ctgatttttc ttttgattgg tgtcttagtt gcttcatgga
      301 ttttatctgg aaccatccct acgattatgg tttatggatt taaacttgtt tctgtgcgtt
      361 tctttttacc gacagcattt cttgtttgtg caattgtcgg agtgactgtc ggcagttcat
      421 ttacaacgat ttcgacgatt ggaattgctt ttttggggat cggtcattta cttggattca
      481 atgatgcaat gactacaggc gcagtcgttt ccggtgcctt tttagggaat aactgctcgc
      541 ctttatcaga tacgaccaac ttggcagcgg gtattggagg agttaatcta ttcgaacata
      601 tcgctggtat gcgttatacg gatttcccag cattcgtcct ttcgttgatt ttttatacga
      661 tattaggaca taacagtcat tcagccgatc tagctagtat caatgaaatg atccaaaaca
      721 tgaaagcgag cttttggatc tctccttgga cattgattcc actagttatt ttatttgggg
      781 gggcaatcaa aaaaattccg gctatcccta cattactagc gggatcgaca gctgctctcg
      841 ttctttcttt tatccatgag aaaagtttga cggtcggaaa agcagcagac atcttgatga
      901 atggttatgt cgcaaataca cctgatccaa agctagatga actgctttct cgaggcggga
      961 tcatgagtat gttaggttct gctagtttga ttttacttgc attggcatta ggtgggttac
     1021 tgatcaaata tctgatcgtt gataccatcg ttcaagaatt aaaagaaaag atggaccgac
     1081 cttctcgttt agtcgggttt actgccttga gctgtatcgg aatcaatctg atcgttggag
     1141 aacagtatct gtccatcatt cttccaggag aaacattcaa gcgttctttt gatgacgttg
     1201 gcttatcaaa aacctatttg acacgaacac tagcggattc aggtgcgacc gtcaattctc
     1261 tcgtaccgtg gggagtcagc ggcacattca ttatgggaac gatgaaagtt agcgcgttgc
     1321 attacttgcc attcgccttt ttctcgattc ttgcacctgt ctttacaata ttaggcggtt
     1381 ttttattgaa tcgtcgacgt gtaaaaaatt gaaggaagga aaaaagaggc tgggacagaa
     1441 gcgtttaact ccaagaaata agaagaaact caagaaaatt gctttttaaa tttttgtgaa
     1501 tttcagctta tttccgaagg agttgcttct gcttccgccg tttatacgtg tttagagcgt
     1561 gagacaaaag tgttctttac ttttgtccca cgctcttttt tacagataaa caatgtgtta
     1621 gaagtagtat cttcttttac ataaaaagct gaccatagga taaatggtca gcgtatttag
     1681 tgagtcagct atttagtatg ggttttctaa aggaacgact gtctctcttt tgatcaagcg
     1741 atgagggatg accaaacgta cgccactgct caattcttca tggatcaatt cgcgcagctt
     1801 ttgcatagcg acacgtccta attcggagat atcgatatcg atacttgtaa ggtaagggtg
     1861 tgttaatgtt gagaagatcg agttgttgaa gctaatgacg gagagtgtct ctggaatgac
     1921 atagccatac atttgcgcca actgcatcgt gcgaagggcg aagatatcgt caatgaccac
     1981 caatgctgtg gcttcgtttt ctttcaacgt tttctcaaag gacagataat cctccggatg
     2041 ctctagtact acactggata acgcaggaag accagccatc atcattgctt tttgataacc
     2101 gaaatatcgt tcgaaataca aactttcatg agtcgtgttt gtcacaaaca ggatattctt
     2161 atgtccattc tggatcaaaa attctgttgc ttgtttacct agaagctggt tatcattatc
     2221 tacataaacg atttcgttct catgatgata aggctgtccg atcaaagtga aagggatgtg
     2281 gttttggtat aaataatcaa tgacagtatc ttgactatct gaatacacta gaataaaacc
     2341 atctacttgt ttttgtaaat gcatacgctg gacgttctct aacagcaatt caaaattttt
     2401 agcagtagcg attgctgtag tcatatcata attccgcgct tcttcgttga ttgcttccat
     2461 gatctcaaga taaaatgggt taccgatccg ctcttttgaa tcaagagggg gtaagattac
     2521 gccgatggca ctggaaatgc gttttcctag attgcgggca gtcatgttag gaacataacc
     2581 tagttcatcc ataatttttc ggactttctt ctttgttgtc tcggaaatac taggatgatc
     2641 gttgatgaca cgagagacgg tcgaggtggc aacaccggct tttttcgcca catcttttac
     2701 ggtaatagcc atgataaaaa cacctttctc ttgttattgt gcagagaacc gataaatcgt
     2761 ctgactgatc cgttcttgac caggatggag gttgatcgat ccaaatttgg ggaaatgaac
     2821 gatatcaggg atttcttgcg gttcgattgc taatccgtag tttgaatgca tctgttttcc
     2881 attgacagag aaatcagctt cgaatccagt cgtagaaaat aataccatac ttttattaga
     2941 agttgctata gtcatttggc gaccagaatg cttctcgaat aattgtaagg aagttttgga
     3001 aagcctagga tgatgcaaaa gaaatacatc atctagtcca tctggataac atgcaaggat
     3061 ctcttgcagt gttggggatt ttctaaagtc gattggcagt ttttcttttt ttgtccaatt
     3121 tccagtaggc agtttttctt gatctaattc aagcacacca tctaaaaaga ccgttaactg
     3181 atgttcatag atgtctcttg ttccatttcc tgaaaggttg aagtaggcat ggttggtcgg
     3241 attgcagatg gtttcaacaa ggctactagc agaggttgtc atctctaatt cgttttttgt
     3301 taaacggtaa gtgatcgtag cagtgattgg tcctggatag gtagaaaatt catcttttaa
     3361 gtaaaagacc acacctattg atgatggagt tttgaaaact tctacttccc aaaattggaa
     3421 agaccagcct ttcgtgccac cgtggatatg gtgtgatccg cagtttttct ccaatctatg
     3481 ctcaccccaa gaagcatccc ggatccttcc ggctacaggt ccgacagttg ctccaaaaaa
     3541 gcttttgtct gttagaacat cttcgaaacg atcgtaagac aataaaacat tttctgattt
     3601 tccttctttg tctggtgcga agatttggtg caggcgggca ccgtaattga gaagaacgac
     3661 ttctaagtag tcgttcttca atgtgatttt ctttatttca gtctctggaa ctggtacgac
     3721 ggagatctct ggattatcca tggtcatgcc acttttcttt caagtaatcg atcgtaagaa
     3781 aagtcgtatc agggacaagc gggatctcct ctccaaggtc ttcagcacgt cccacgccaa
     3841 ttggttgagc gccacttgag aggatggctt ggataccggc ttgcgcgtct tcgatcccga
     3901 tacattcttc tgcttttagt ccgacagctt ttgctgcaag gaggaagata tctggcgcag
     3961 gttttccgtt tgttgcttct gccgggtcgg caatagcatc aaagtaaggt gtaagaccca
     4021 ttttttcaag taggaatggc ccgtttttac ttgcagaagc aagagcaatc ttgatttttt
     4081 cttcttttaa agaatccagt aaaggcacga ccccggggaa gacatctttt ggttcgatcg
     4141 tctggatcat ctctaaataa taatcgtttt ttcttttcgc taattctgca aattcttcct
     4201 ttgaaaaaga gtgttctttt ccgccataag ctaaaagcaa agagagtgag tcttctcggc
     4261 tgacgccttt tagctgttcg ttgaatgtgt ggtcgatcgt aatgccgatt tcctgaccaa
     4321 gctttcgcca agcacgataa tggaattcag cagtatcggt aatgacaccg tctaaatcaa
     4381 acaatacccc tttaaacatt tgcttcctcc tttcttagcg ttatttctag acgatccgct
     4441 aaagaataag actgttcata gacgtaaatt tctagaggag aaccttctaa taactcgaaa
     4501 gtaacttgtt catctgtgac tgagatgaac aataaacgtc cgcgataatt gatatggaaa
     4561 gaataagctt tccaagtttt tggcagaaat ggtgcgaatc tcaactgatc atgggcagtt
     4621 ttcatttgag caaatccttg gacaatcgac aaccagctac cagtcatgga agtgatgtgc
     4681 aagccgtctt ctgtgtcgtt attgtaatta tccaaatcca agcgagctgt tcgctggtac
     4741 atttctacag ctttgctttc cattcctaat tctgctgcta aaatcgaatg gatacttggc
     4801 gaaagggaag actcatggac agtcattggt tcatagaaat caaagttttt ttgcttttct
     4861 tcttttgtaa aagtatcatt gaagaaataa atcccctgta gtacatctgc ctgcttgatg
     4921 aagcaagatc taaggatttt gtcccaagac caatgctgat tcagaggaag atcgcttgtg
     4981 ggaatatcgg atacaggcat gagatcttta tctaagaatg tgtcatgctg gacaaagatt
     5041 cctaattctt cgtcaactgg gaagtacatg ttctctgcga tatctttcca tttggctagt
     5101 tcttcttcgc tgatagtgat agcagcttct ttttgataag ttaaataatt ttctcgcgtg
     5161 taacgcaaga cccaagctgc gatcgtattt gtataccaat tgttattgat attgttctca
     5221 tattcgtttg ggccggtcac accgtggatc atgtatttat ttgctcgttt tgaaaaatgg
     5281 acacggtctg cccagaagcg tgcgatttct gctaaaactt ccagtccttc atttttcaaa
     5341 tattccgtat cgccggtgta attcgtataa ttgtagattg cataggcaat cgcgccattt
     5401 cggtgaatct cctcgaatgt gatttcccac tcgttatggc attcgacacc agtgaaggtg
     5461 accataggat aaagcgcgcc ttttaatcct tgttgctgag cgttgtggat tgcttgcggc
     5521 agttgattat gccgatattt cagcagattc ttagttactt caggtttggc taaagcaaga
     5581 taaagaggga cagcatacgc ttctgtatcc cagtaagtgg ctccgccgta tttttctcct
     5641 gtgaatcctt tggggccgat attcaatcgt tcatcttcgc cgtagtaagt agagaatagt
     5701 tggaacaaat tgaatcgaat accttgttgt gcttcttcgt ctccttcgat gaccacatcg
     5761 gcaagcttcc atcgttctgc ccaagccgct gtttgctctt cttttgcttg gatataattg
     5821 tttgtctggt tcgttaattc tgagacagct ttttctgctt gctgcgcttc tggaatatct
     5881 ctactagtaa gaacgataat ttctttttcc actgaccatg tctcaccttg agataattct
     5941 gcagacaagc aaccatgtaa tgctaaagta tcttcgtgat agtcagggat gactgatttt
     6001 ccattaacga aatggcgcat tgctgcagta acagtaaatt gttcaatccc aaagttgttt
     6061 ggaatagttt tagtcgtcaa atagccgatt tcttctatag ttccacgatc aatctcattc
     6121 caaaaatgtt catcatagtt gctgtcttcg ttttgaacat ttccatccaa ttttgatacg
     6181 agtttgactg ttccgctacc ttcaagcatt tctatagtta aatagatata agctgattct
     6241 tttttgacaa tgctcagaaa acgttcgaag gaaatgcgta ctttattagt agaagtagtg
     6301 attgtgaatg tacgagataa tacaccattt ttcatatcta attcccagta aaagtcttct
     6361 ggttccaaag aagccaagtc gatcagctga tcgttgatcg aaatatctat cgcgataaag
     6421 ttcaaggcgt tgatcacttt tccaaagtat tctggataac catttttcca ccagccgaca
     6481 cgtgtcttat cgggatacca gacacccgcc aaataagtac cttgatggtg gtcccctgag
     6541 taagtttctt caaagttccc gcgcatcccc atataaccgt ttccaatact tgttaaagat
     6601 tcttgcagtc gaagattttt tttatctaat tgtgtcgtgc tgattttcca tggatcaata
     6661 gcaaatagtc gtttgatctg tttcattttt ctcctcctaa tgagctgttt tatacgttca
     6721 taataaacgc aaccgattgc acaagtcaat agacaaaaga aaatatttca tagaaaaaag
     6781 cttaaaaaaa taaattttta ggagaaaatt atagaaggga acacacgtat tataggtttt
     6841 atagaatggt atagacagaa aaataaaaaa taaagcattt acaaaaaaga aaacgcacgc
     6901 tataatacgt ttaacgaaac cgattgcgta aaggagctaa acggaatgaa aaagatattt
     6961 agttttgagt tttggcaaaa atttggaaag gctttaatgg ttgtggtagc agttatgccg
     7021 gcagctgggt tgatgatcag tatagggaaa tcaattccct tgatcaatcc tgattggacg
     7081 ccgcttgtca caacgggcgg agtaattgaa aatattggtt gggcaattat tggtaatctt
     7141 catattttat ttgctttagc aataggagga agttgggcaa aagaaagagc aggcggagca
     7201 tttgcagctg ggatctcatt tattttaatc aatcggatca ctggggctat ctttggtgtc
     7261 acaagtgaca tgcttgcgaa tgaagatgca tttacccaca ctctgttcgg tacgaagatc
     7321 atggttaaag gattttttac aagtgtattg gaagcaccag ctttgaatat gggagtattc
     7381 gtagggatca tcgctggatt tgtcggggca atggcttata ataagtacta taattataga
     7441 aaattgccgg atgctttgtc atttttcaat ggaaagcgct ttgttccgtt tgttgttatc
     7501 ttatggtcaa caatcgtggc attgattctt gctgtggtgt ggccaaacgt acaggctgga
     7561 atcaataatt ttggtttatg gattgcagaa tcacaagaaa gcgcaccgat tctagcaccg
     7621 tttttatttg gaacattaga acgtttacta ttgccatttg gattgcatca tatgctgacg
     7681 attcctatca actatacaca gcttggcgga tcgtatgaga ttttatcagg cgcacaggcg
     7741 gggacacaag tatttgggca agatccgtta tggttggctt gggccactga tttagtgaat
     7801 cttaaaggtg caggggatat gtcgcaatat gagtttgtgt tgcataactg gacgccggct
     7861 cgtttcaaag taggacaaat gattggttct tcaggtatct tgatgggaat ggcttttgcg
     7921 atgtatcgta atgtcgatcc tgataagaaa gcaagatata aatcaatgta tttttcagca
     7981 gcgttggctg tctttctaac aggtgtaaca gaaccattgg agttcatgtt tatgtttgct
     8041 gctgtgccat tatatgtcat ttattcagtg atccaagggg ctgcatttgc gatggcagat
     8101 atcttgccat tgcgggtcca ttcatttggg aatatcgaat tgctgactcg gacaccgtta
     8161 gctatcaaag cgggtctagg tggagatctt atcaacttcg tgttgtgtgt gatcgctttt
     8221 ggtgttgtta cgtatttctt agcaaatttc ttgatcaaaa aattcaactt tgctacaccg
     8281 ggacgtaacg gaaattacga caatgacagt gaagaaaccg ttgtatctaa cagcggaaca
     8341 ggaacagcag atcagcaagt ggtccagatc attcatttgc tgggaggaaa agaaaatatc
     8401 aaagatgtcg atgcttgtat gactcggtta cgcgtaagtg taaatgatcg agaaaaagta
     8461 gggactgaag aagcctggaa acgagcaggg gcgatgggat tgatcgtcaa agacaatgga
     8521 gtccaagcag tttatggacc aaaagcagat gtcttgaaat cagatatcga agatctgctg
     8581 caatcaggag cagagattcc agagccagaa atggtttcta caggaaatgg acaagcaggt
     8641 agtaagcaat acttaggtat agaacaagaa ctagtttccg cagcttctgg agaagtgatt
     8701 cctttatctg aagtaaaaga tccggtattc tcacaaaaaa tgatgggtga cggctttgct
     8761 gttattccaa catcaagaga agttgttgcg ccgatcgctg gaaaagtgac aagtattttc
     8821 cctagcaaac atgcaattgg gctggaaacg aaagatggta tcgaagtttt gatccatatg
     8881 ggaatcgata cagtccaaat gaatcagcca gcttttgaga ttgctgtcaa agaaggccaa
     8941 gaagtaggaa caggaacgaa attagctgag atggatcttg atgtgatcca aaacgaagaa
     9001 aaagatccaa cgatcatgat cgtatttaca aacgataaag tagaagaagt agtgatcaag
     9061 caattaggta cagtgacagc tggtaaagtg atcggctcca ttaaaatgta aggagaggtt
     9121 gtgaaaaagc tgtcctgcat caagtcataa gaacagccaa acaaaaatag ctcctcctat
     9181 ttttcgtttg gttgggctta ttaccgagaa gcagcagttt gaatactgtt tagtggagag
     9241 gtcgtgaaaa agctgccctg caccaagtga taaaaacagc caaacaaaaa atagctcctg
     9301 gtccattgag cttattactg aggagttagc aggagaacac tatttgctgg agaggttgtg
     9361 acaaaaattt tgtcacaacc cttttgtttc gaaatgaaga caaggagaaa accaatgaaa
     9421 ttcatgacac tcaacacgca tagctggctt gagccagaac cagagaaaaa attgcaagaa
     9481 ttagcagata agatcctgtt agaagattat gaagtgattg ctttacaaga aatcaaccaa
     9541 ttactggaat ctgaagaagt agaacctgcg aagctaatga agttctgtcc ggtaaagaat
     9601 caagtaccta tccgtaaaga taattttgcc taccgtttag ttcagctttt aaaggaacac
     9661 ggaaaagagt atttttggag ttgggaaatg agccacatcg gttatgataa atatgaagaa
     9721 ggaaatgcac tgcttacgaa aaaaacattg gaaagtcagg tccttaccgt ctcccaattt
     9781 caaaagaaag aagattatca gacacgcaag atcttgattg ggaaaacaaa gatagatgat
     9841 caggacattt ttgtctcgag ctgccacttt tcttggtgga cagataaaaa aagtggcttt
     9901 tattttgagt ggaaaaactt ggaaaactac tttttggaaa ctcgcgtacc actttttttc
     9961 ctaggtgatt tcaataatcc agtagactct caaggttatt atactgtaag agaaagttgc
    10021 cttcttcttc aagattcgta tgttgtcgcg aatgaaaaag gaaaagcagc tactgtggaa
    10081 aagaaaatag atggttggga acaaaataca gaaaaattgc gtatagattt tattttcgtc
    10141 cctgaaggaa tgcaggttaa aaaatatcaa cggatttttg atgggatcga tagtccaatc
    10201 atcagtgatc actacggggt ggaaatcgaa ttagatgtga acgaataaaa aatataacat
    10261 ataacataaa aaaactgatt aaaataaaac tctccaaacg attataccgt ttggagagtt
    10321 ttttgatcgg atgtatttat cccttttgcc taagcacgta aaagcttgta tctatgataa
    10381 ataaataaac atagcaaggt aaaccagcca atcaaagtaa gagaaagaat gaaatagaaa
    10441 tagattggcg tttgataatg aagcgtgagc tcgttgattc ctttttgctg cttcacgatt
    10501 ggggtcccga tatctgttac ttcataatca gtcaatgttt ttccattttg ctgtagcaca
    10561 gtccgatcgt agacgataac agggatatga acagttttgt ccccagtgtt tttccacttg
    10621 attgtcaaaa gaccgcctgg atgtgttttt ataaaagttg tttcgttttc tagtatttct
    10681 tcgttatacc ggtcgtattt attgtctttt gtctccttat agattggcag atagtcaggt
    10741 gtggtttttt ggaaaacgaa caagctggta gacatatctt tgctgaagaa tgttttcctt
    10801 gcttcttccg gcgtatcgaa tagataagta tgtcgactga caaatgtttc attttcccac
    10861 ttttccagat gctggtataa gttctggatc gtctgtgctg aaaaaataag aatgccaaat
    10921 atacttaaaa gacggaacca cttttgttca gaccactggt tcagtgaaag ggcaaggtaa
    10981 agtagaagca atagcgtaaa tggcacgaaa aatcgaaatg gaaactggat caaactaata
    11041 aaaggcacat ttttttcgat caatgtcgtc catggaatca agctagtaga aagaaaaaag
    11101 aaaacaagac ttgtgtacaa cacgattttt tggaataagg tgttcttttg ttgaaagaaa
    11161 ataaaaagca aaaaacctga taatatcaat ataggaaagg ccttagggta atggagccaa
    11221 taactgccat ccagatctat cgccttttga ctcatttctc tgttaacaaa gggaggaaga
    11281 atcttattcc cactgtaaac aatagctaat cctgcccaaa tatttgctgt cagaacaaaa
    11341 taaagcaaga ccgacttaat cagttgaagc agtgcttttc ctttttcagt ctggttaaaa
    11401 aagtaataaa gataaaaagg gatatacatc aaagctaaca tgatcgaaga cagtaaatgg
    11461 atctgtgtca taagtcccac tgagacagcg actttgataa cagggaactt tttatgaagg
    11521 acgaaatcag caatagggat catacataaa ggataaaaac aagtccccca gctagtgaat
    11581 ccttggttga tagaccagta ttgaatagaa tacgtactca tgaataaaac ggctactggt
    11641 acacttaccc aatttcgaac attgacatat ctcagtaaaa tcagcataga aaatcctgaa
    11701 ataagataaa gaatgaaatt tgaaagaatc tgataatgaa accagctacc tgcaagcaac
    11761 acgatcaatc cttgtaaata agcgaaaaat gggccgtaaa cggcattcac gatcctgcca
    11821 ctttgctgga atccataaag ggaaggaaaa taatggaaat ccccatattt aatttgttgc
    11881 gcggcatcat agaaccgatt gtaatggaat ggggcatcag cacccaaaat tagtttatgt
    11941 gtgaataaat gaggcatgag aaatgccaaa gcaatgaaaa aaattgctaa aaatgggcca
    12001 tattttttca attgtcgaac tcctttgcaa actttagata aattcatcat atatcctatg
    12061 cgagaggtag gcaagaaatt agaaaattca tgaaaatatt tatgaatttt acaagaaaaa
    12121 cataagtgaa agttctaagg agagaggatg cgacataagt tttgttgcat ctccttgttt
    12181 tgaaacagaa tttttcttaa tactcgaaac aaagtagctt tttcatgacc tctcggtaaa
    12241 cggtgttcaa tcagctgctt ctcggtaata agctcactag cctagaaaat atgagaagct
    12301 attttctgac tagcgctctt attactcaaa gcataacgca gttttcacaa cctcttcctt
    12361 aaacggtgtt caaaagcttg catctgcggt aataagccca acccaacaaa aaatatgagt
    12421 agctattttt ttgggctgta cttattactt gatgcaggac agctttttca caacctcatc
    12481 ggctttcatt ttctattttt ttcctgaacc catataataa aagaaagaac aaaaaaactt
    12541 gcaagggagg acacatgtga agcagagtaa gcaaaaacag tctcgtcgac ttttgtttcg
    12601 tttgttttta ttaatatgta tcgtcgtagg gttactgatc gctttatatc cattttatgt
    12661 ggattcttta aatagtttta ttgatcaaaa acgtatcgaa caagtacaaa aacggaccgc
    12721 agctgaaatt gaagtgcagc gaaagaaaat ggaggagaaa aaccaacgat taactgacca
    12781 aggattcaat cctggtactg atcctttcaa tgaaaagaac agaaatgaaa gtacaacatc
    12841 cagccaatta gaggaatggc tgatcggaag tatcaatata cctaagatcc aattaaatat
    12901 ttcactttat gatcggctca atggtaggat ccttgaaaat ggagcaggcg tcttgcaagg
    12961 aacctctttc ccgcttggtg gaaattcgac gcattcagtg atctctgctc acagcggttt
    13021 acctaatcga cggttattta ccgaattaga tcgtttagaa aacggagaca cgtttatttt
    13081 gactgttttg ggggagaaat tggcttatca agttaaaaat atacaagtgg tactgccaga
    13141 tgacacgtct gttctaacga tttcagaagg agaagactta gttaccttgc ttacatgtac
    13201 gccgtatatg atcaacacgc atcgtttgct agtgacagga catcggattc cttataacga
    13261 atcggtaaaa aaagaagaag gaaaaggaaa tcaggaaaga accatgcggc aatggtttat
    13321 tcttgcagga acgataatag ctgtagtcat actgttagtg tttatcggac gactaatcta
    13381 tcagtataga ttaagtaaaa aagtgcttga tttttcattt attattagtg attcgtcagg
    13441 gaaaccggta aatggtagtt cattcatttt gaaacataag aaaaaaacac ttactagaaa
    13501 tggtgtgccg ttttcagtac aaagcgacca tcatgggaaa gtcaagctgg atcaattgcc
    13561 tggtggaact tatcgaatcg tttcagctga tgatcctaaa gttgctgttt cttttggtat
    13621 tagaaaagta aaacaagaga agatatactt ttttgagggg cgaaaacttg taaaagagct
    13681 tcaaaaaaat ggtttttatt ttaaaatcaa tgaataagta aggagagaaa aaatgatccg
    13741 cacaacaaca aaattgtctg ccaaagaact ggaatctgtt ctatcgattt ggctgcatgc
    13801 taacttggat tctcatgaat tcattccatc aacttattgg gagaatcaag tagaatctgt
    13861 taggaaagct ttaccagatg cagtgattta cttagcagaa atagatcaag aaattattgg
    13921 ttttgctggg gtgattgatc agtttatcgc aggaatcttt gtgaaaaggg aataccggca
    13981 acaaagaatc ggtacgcaac taatgaaaaa aataaaagaa accaataaaa cactgacttt
    14041 gacagtctat caaaaaaatc aatcagctat tcatttctat ctttcacaag gttttacaat
    14101 tcaaacacag caaaaagatg aagcagtaaa tgaggaggaa cttgtgatga aatggaatca
    14161 aaacgctgat ttttgatgaa cagaataacg aaataatgct cccagcctaa ttttttgctg
    14221 ggagcattat ttcattttga agtcactaat ttaactgtgt gaatatgcag ttgttacaat
    14281 ctttgataaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
    14341 tgaggaacta tttttccatt tgtttctcta atactcaggt caaaacgctg atttcacaac
    14401 ctcttgataa acggtgttca aacggctgct tctcggtaat aagcccacta gcctagaaaa
    14461 tatgaaaagc tattttctaa ctagcgttct tattactcaa agcataacgc tgatttcaca
    14521 acctcttgat aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa
    14581 acatgaggaa ctatttttcc gtttctttct ctaatactca ggtcagaacg ctgatttcac
    14641 aacctctctt tcacaacctt attttactcg tttataattt tcatcgaagt attttccgct
    14701 acggatatca tctggcattc catcgtatgg ttcttcgcta ataacatctt cattgtctat
    14761 acctgcatca cccatataag tgatcgtagc aaattcagga acaagtaatt ttggataagt
    14821 ttcatatttt tcacgagctg cttccatttc tgcgatatgt tcgttttgga aagtaacagt
    14881 gatttctgga tgttcttcaa cccatttagg gaaaaagatc attccgtgaa gtttcttttc
    14941 atttggcata aagtccaatg ccacgtctgt ccctgttggc tctgtccaag tgattttgaa
    15001 tacgccgtcc gtcaatttaa cgatatcagc ttcttggtct tttacccaac ggcctttgac
    15061 cattccgcca tggatacggt aatcaacagt atggtcattt ttggcatacc attcatattc
    15121 ccaaccattg tcatacgtat agataaagtg agttccaata aaatcttcca attctttaaa
    15181 ttctttcatg tttaagcatc tccttataaa ttaaaacatg taataaacta catgttttcg
    15241 attactcatt tatgatagaa tggatttaaa gatttgtcaa ggagggaaaa ctgatggcaa
    15301 gaaaaaatac acttcgatat attttgttag ggttattaag taagaagaag atgacaggat
    15361 atgaattgaa tcaatcgttc aaaaatgaaa taggagaatt ttggcaagca aaacatagtc
    15421 agatttatcc tgaacttgca aaaatggaag agcaaggaat cattcagcat caagtagaga
    15481 tcacaggtga aaaattggaa aagaaagttt atgaattaac agaagaaggg aaggaacaat
    15541 tggcagagtg gattcataca cccaccaatg aactaccggt taatcgagac gaatttgttc
    15601 tgaaattgta tttcgtcaaa gacgtgaatg atccggcatt agtagaaatt attcagcagc
    15661 agcgtgacct tcatgaagaa aaacgacttc atctattaga gcgaaaaaaa acgatctttc
    15721 ctactgaaaa agaaaaacat gaaaattacg gacactacct gattttagcg catgcgatca
    15781 atcgggaaac agaatatgca aattggctaa cagatgtatt agaagaaagt aaccgaaaaa
    15841 aataaaaaaa tatccgaaca gtgatggaga attcctttct atatgaaaga aacgcagatc
    15901 accgttcgga tattcttatg ttcaaacagg ccttttttca agtatttatg tagcatctac
    15961 ttattaaaaa gcttggtact taggagatta gtggcgttta gagttctttt aacaactgtt
    16021 cgtagtcagc tttttcatcg acaggaagga gcttgtaagt taattcgtct gtctcgttgt
    16081 catgaatgat gtacatctta gcattctctt ctttgaagtt accgatttgt aaaatcgtat
    16141 agcgttcgtc gatcaattcg atatctttga ttgcttttga aaaaacttta cggacatggt
    16201 gcattttctt ttggcggatt tctgcctttt ctgcagcttt tgacaaagta aatccgtcat
    16261 ctaaatattt tttgatcagt tctactttta tgactgtagg taaacgatat tttctaggac
    16321 aattcgcatc agcttcgatc gaacgaatga atcccttttg ttcccaatac cttaattgac
    16381 gtggagacac acctacgata tcacttaatt cactgatgcc aacaaccaat tgatcatttt
    16441 ccaacaaacg tttaagggaa gccccaacca tttttgtcac tccttttgtc ctcttgcttc
    16501 ccttaattat atccgtatta acttatgtgt caagtaggtt gacaaatagc gaatttagga
    16561 ctaaagtatt ctagtagttt cagaaaaaat tcagaaagaa ggagaaatat gagtaacaac
    16621 caacccgtag atatttacgg aaaaccatat aatcggacac ttttagttgt tgtcttatta
    16681 attggtacat tttgtaccgt tttgaatcag accttattga cgacagcttt tcctacattg
    16741 atgaaagctt tcgatatttc agcgtctgat gtgcaatggt taacgactgg tttcttgcta
    16801 gtcaacggga tcatgatccc aataacagca tggctgatca ataaattcag ttcaagaaat
    16861 ttatatcttt ctgccatgac gatctttttg atcggaacga ttacttgctt tacagcacct
    16921 aattttagta cattactaat cggtcgtttg atccaagctt gcggtgtggg agtatcgatg
    16981 ccattattgc aaaatatcat gctatctatt ttcccgccag aaaaaagagg atcagcaatg
    17041 gggatgtcag ggatcgttat tggacttgct cctgctttag gccctacatt atctggttat
    17101 atcattgata actaccattg gcgtgacttg tttggtatgg tactgccaat cgttgttctt
    17161 gtcttggttt tagcattctt cctaatgaaa agtgttattc cattgtcaaa tcctagcatt
    17221 gatattttat ccgctatttt atcaacgatt ggattcggta gtttacttta cggattttct
    17281 agtgtaggag atgacggctg gggaagcttg aaagtaattg gtttcttagt tgttggtgtg
    17341 attttcatcg ccttgttctc atggcgtcaa ttacatttgg aacatccatt cttggaactt
    17401 cgtgtattca aatcatctac attcacgatt gcagctgttt tagctggtgt aacaaatatg
    17461 gcgatggtag gggcagaaat ggtcgtacca ttgtatattc aaaatattcg tggagaatca
    17521 gcattccatt ctggcttgat gttgttgccg ggtgcattga tcatgggggc tatgatgcct
    17581 gtgacgggtg cgattttcga taaatacggc gcgaaacgtt tagccatcac agggatgttc
    17641 attttgacag cggcaactgc accatttgct ttcttgacaa aaacgactcc agttttatat
    17701 atcgtgatcc tttatgcgat ccgtatgttt gggatctcca tggtcatgat gccggtaacg
    17761 acttctggta tgaatgcatt gccaaataac ttgatcagtc atgggacagc ggtaaataat
    17821 acattccgtc aaatcgcaag ctcgattggt acagctattt tgatcagtgt gttgacgaat
    17881 gtgacaaaag caaatatccc aagcaaatct gtattggata atacgccatt agcttataaa
    17941 gatcaggcaa tcaatgccac actgtcaggt taccatgccg cgtttatcgt agcgatcatc
    18001 tttgggattc ttggctttat tattgccttt ttattgaaga aaaaagaacc tgttccaatg
    18061 aaagcggggg ataatgcatg attattggag ttttgattgt cagcttgctt gcttttgctt
    18121 taacgaacgt gttcgctaaa aaaacatggc aaaccttttt atctttgatt ttcggactaa
    18181 tcttcgtcgc ttcactaagt ttgatcgtcg ctaatttgtc caatcacttt ggaatggaaa
    18241 aagtaacgga aacaaaaaca gaaaaaattg tttccagtgc tgattcccaa ggagcagata
    18301 tgcttttgta taaagcttta gggaatggaa aagaaaaagt gtatctttac cgaacaaatg
    18361 aaaaacaaga aaaaccaaaa gcaactggta cggataacga aacaaataaa gtagaaaaga
    18421 cagacggcga tgctgaaaaa gtgacgaaaa ctacttattg ggaatacaaa aacgacatgt
    18481 ataaattctg gttcaatatt gctgataaca atcacgaata tgacagccga gtgaatacat
    18541 tcaaaatccc agagacatgg gtagaattaa gtacggacca agcagccaag ttagctgaat
    18601 tagtgaagaa acagcaaagt acgatggaaa gtgaagcaaa agcttatgtt caagacggta
    18661 tggtaaaagc aatgactgaa aatccaaaaa tgagcaaagc agagcaagaa caacgtacga
    18721 aagccttagc tgctgaattc caacaacaag cattcgcaaa attagtgaaa gaagcaaaag
    18781 gcgaataata ttttgaacac catgta
//
LOCUS       DAZKPE010000050        18701 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000050 DAZKPE010000000
VERSION     DAZKPE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.050"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            393..557
                     /locus_tag="ACG930_001979"
     CDS             393..557
                     /locus_tag="ACG930_001979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519135.1"
                     /translation="MPATLNAYDGYDYRKKIVKKLYGATYGNVVSVLSVHHQASVTVA
                     EVEDAAVNGE"
     gene            753..920
                     /locus_tag="ACG930_001980"
     CDS             753..920
                     /locus_tag="ACG930_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFQ0519136.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            946..1290
                     /locus_tag="ACG930_001981"
     CDS             946..1290
                     /locus_tag="ACG930_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFQ0519137.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            1295..1576
                     /locus_tag="ACG930_001982"
     CDS             1295..1576
                     /locus_tag="ACG930_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519138.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            1679..1993
                     /locus_tag="ACG930_001983"
     CDS             1679..1993
                     /locus_tag="ACG930_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFQ0519139.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            1971..3665
                     /locus_tag="ACG930_001984"
     CDS             1971..3665
                     /locus_tag="ACG930_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFQ0519140.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            3685..4863
                     /locus_tag="ACG930_001985"
     CDS             3685..4863
                     /locus_tag="ACG930_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFQ0519141.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            4826..5512
                     /locus_tag="ACG930_001986"
     CDS             4826..5512
                     /locus_tag="ACG930_001986"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFQ0519142.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            5512..6672
                     /locus_tag="ACG930_001987"
     CDS             5512..6672
                     /locus_tag="ACG930_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFQ0519143.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            6682..7557
                     /locus_tag="ACG930_001988"
     CDS             6682..7557
                     /locus_tag="ACG930_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519144.1"
                     /translation="MKYILCQLAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            7554..7865
                     /locus_tag="ACG930_001989"
     CDS             7554..7865
                     /locus_tag="ACG930_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519145.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            7855..8208
                     /locus_tag="ACG930_001990"
     CDS             7855..8208
                     /locus_tag="ACG930_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFQ0519146.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            8198..8599
                     /locus_tag="ACG930_001991"
     CDS             8198..8599
                     /locus_tag="ACG930_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519147.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            8592..8996
                     /locus_tag="ACG930_001992"
     CDS             8592..8996
                     /locus_tag="ACG930_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519148.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            9008..9616
                     /locus_tag="ACG930_001993"
     CDS             9008..9616
                     /locus_tag="ACG930_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0519149.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            9636..9998
                     /locus_tag="ACG930_001994"
     CDS             9636..9998
                     /locus_tag="ACG930_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519150.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            10001..10183
                     /locus_tag="ACG930_001995"
     CDS             10001..10183
                     /locus_tag="ACG930_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519151.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            10200..13619
                     /locus_tag="ACG930_001996"
     CDS             10200..13619
                     /locus_tag="ACG930_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFQ0519152.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFERNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNSLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTVSNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SGIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            13670..14407
                     /locus_tag="ACG930_001997"
     CDS             13670..14407
                     /locus_tag="ACG930_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFQ0519153.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            14417..16708
                     /locus_tag="ACG930_001998"
     CDS             14417..16708
                     /locus_tag="ACG930_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFQ0519154.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            16732..>18701
                     /locus_tag="ACG930_001999"
     CDS             16732..>18701
                     /locus_tag="ACG930_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519155.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGNYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFVD
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDGPYWLGKVPLGENIADPTVVFPHKTSEY
                     MVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMKPTEGLANTWELT
                     FTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNISEYKYRGTGMRD
                     SNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTT
                     AKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFV
                     ALNGKSSGGNDSTILTIPEGYRPPISFEQLVGS"
BASE COUNT         6609 a         2788 c         3942 g         5362 t
ORIGIN      
        1 ttttgagtaa atagaacaaa aaacctgcac tagtttccgc tagtacaggc agtgactata
       61 tcggttgata atctagcata tattaaaaat aattgcaaga aaagaaattt atagtggttt
      121 ataccaaatt atcaaagcaa tgttattttg ttgctgtcta ttgtttttta attattcaca
      181 cgataactaa aggtgggtga agagaaatga ttccattaat aatttcaatt tttgcgctct
      241 gtcttaatgt ctatatgatt ggatttaaaa atgggcaaaa taaaaaatag tagcagccaa
      301 gaataatttt atagtgtcac tgtggcggaa agggtagacg ctaagcatgt gtgctaggtc
      361 aatgcttcgg caaccatgca aggttcgatt ccttgccagc gacattaaat gcctatgacg
      421 gttacgacta ccgaaaaaag atcgttaaga agctatacgg tgctacgtac ggcaatgtag
      481 taagtgtgct atctgtacac caccaagctt cggtcactgt ggcggaagta gaagacgcag
      541 cggtaaatgg cgagtagcct cgtgagagcc tggtaagttc tcgtgagtgg tgcaatccca
      601 ctccagcgac tttaagcaac cgaggcatcg gcggtttaaa aatatagggg tgcgcaattt
      661 cgtacgcgtt ttgtgcatcg tgcaagttac tattacatat tagatcactc tttgagtggt
      721 ctttttattt ttgcacaaag gaggaaacaa caatgtatag accacaatac ttagaacaga
      781 agtatgaagt aatcactgtt cataaaggta atggcgaaaa agtatatgag tatagaagac
      841 caataaagag cgatacatat aaacgaaagg aaaacaatga agttattcca ttgtatggca
      901 aaagaatagc taagcattaa ataagattgc gaaaggagac ggaacatgac cgaggaattc
      961 tatagatggc tattacagtt gacaagagaa gatcgtttgg ttaagttcta tcagtctcct
     1021 aaatggcgca ggcttagaga gaaagcgatg aaacgagatc actatgaatg ccaagagtgt
     1081 agaagactag gtaagtatca tagagtagag aacgttcatc atataaagga agtcaaggat
     1141 agacctgact tagctttaga tttagataat cttatttgtt tatgtgttga acatcataat
     1201 gaagttcatg gcagatatct tacagcatta gataaacaag agaagaagat agaaagcttt
     1261 gctaacttcg atgcaagtga aaggtggtaa gtgcatgatc atcaatgata atggcagaga
     1321 gtatgataca gaaaagattg aagagtattc atcttatact cagggattaa ttaaacgttt
     1381 gatatacgtt cgctatgtag gtattaggga tctgttatca gataactgtt gtagtaaata
     1441 caaagtgaat caagtaagag aagcgttgaa taaagataat aacgtcgaaa gaataaaaaa
     1501 tgtttttgga tatagtattg aagagattaa ttattacatt gacttcgctg aagctttcat
     1561 tccgatggtg agataacccc cccttaaaat aaatcgcaaa ttttttgggg gtgatgaaac
     1621 ggagggggct gtcaggaaaa gagatttttt cgaactttat catgaaagga gggctaaaat
     1681 gtttaaaaac gaattgtctc aaaatcgcta cagagaaaaa ttacgccgct ctttaataag
     1741 ccaattggaa agtcagaaaa caaatattga gccattctta gataatgttg atcgttatat
     1801 cagtttatgg gaaacggcga tatcactgga agaagatata tccgagaacg gcattagact
     1861 ggagaatggt aaaaagaatg aatcagtagc gttgcttgtt tctgtcaaca aacaaatggg
     1921 attgatgttg gataaacttg ccattactcc tgaattggta ggtgaagcaa atgaatcaat
     1981 tcctgagtta taagcatatt gaaaattggt tcaaagctat agaagaaggc actatcaagg
     2041 tatgcaaaga gcaattattg ctaaaaaatt atctagaaga aagagtcttt actagagaag
     2101 atatttactt cgataagcag atggtagagg attcaatcaa tataccagca caatactttc
     2161 cattcgaatt aattccgtgg gaaaaatttc tacaatgttt tatttatggt gttcgatgga
     2221 aaaaagataa aacactagtg ttcaatagat atctttcatt aatgggacgt ggtaatggta
     2281 aaactggttt tgcttcttgg aacaacttct ttctactaac cgctaaacac ggtattaaaa
     2341 attatgatat tgatatctat gccaataatg aaagccaagc aaagactagt tttgatgatg
     2401 tatttaaagt aattaaagat catcctgatt tagataaaaa agtatttaaa gctacgaagg
     2461 aagttattca aaatatcgct acaaacagca aacttcgtta taacacggca aatgctagaa
     2521 caaaagatgg gaagcgacca ggtgcaaacc gctttgatga aattcacgaa aatgaagatt
     2581 attcaatgat aaatgtggct acttctggtg gtggtaaaat tcgagattat agagaatttt
     2641 atgatacaac taatggtcat gttcgtggtg gtccgcttga tgacattata gaagaatcaa
     2701 aaatgattct ttctggagaa cttggaattg acaaggatgg agcagaattt tctagtttgt
     2761 ttccatttat ttgtcgcttg gataacgata atgaagttga tgatcccgac atgtgggaaa
     2821 aagcttgtcc aactattaat tacaatgcag atttaaaacg gaaaatgttt caagaatact
     2881 ctcaaatgca acgtaatgct ggtttaagac ttacgttcat gaccaaacga atgaacagac
     2941 ctatggaaga tacacgattt gctgttgctt catatgatga tgttctgcat acgaaagaaa
     3001 aagaatttcc tgaaaaaatg gatgaagtga taggaacagt cgattttgct gatagacgag
     3061 attttgccag cgttgggttg ctaggaaaat acgataaaga tgtttatttt acacaacata
     3121 cttttatcca cgaatcagcc cttcgattac aaaacatcaa acgagaggtt atagatattt
     3181 ctatagatca aggaaaatca cagatcgttc atggaaaaaa tatagaagct gattatattg
     3241 taggttggtt tcttgaaatg agtaataaat attatattaa aaaaatcgct atggatatgt
     3301 accgtgcaaa aatattgaag cccgctttag aagaagcagg ttttactgtg gaaattgttc
     3361 gaagcggatc tgttacacat ggtatgttaa aagatctggt tgatgacctt tttattaatc
     3421 aacgtttatt ttttggtgac gatgcgatta tgcgttggta ttgcatgaat gtatatgaag
     3481 agcatatttc taatggaaat atacgctatg aaaaaataga acctgaaact agaaaaacgg
     3541 atggcttttt ttcattcctt catggtttga attttttaga tgatatttat gattctgctc
     3601 ctgtaacagt cacaaatagc tcagtagaaa atacaggaac tggatttact cctctagtat
     3661 tctaacttga aaggaggtga gaaagtgggg atttttcaaa aggcggtagg atacttcaca
     3721 aaaaaagcaa cggttccttt agaagaatac ttttgtaaat tgcaagttga ttttgtgtat
     3781 cgaaaatttg cgattgaaac ttgtattgat ttgattgcaa atgcgatgag taaagcggaa
     3841 ttcaagtcat atgaagatgg aaaaaataaa aagaatgatc tttactatag gctgaatgta
     3901 gctcctaata agaaaaataa tgcaacagaa tttagaaaaa aactgatcag gagattaata
     3961 ttctacaatg aagtattgat cgtttctccg tctaataatt ctagcgaaat atttattgcg
     4021 gatagttggg atgtcacaga atatgcattg aaagatgatg tgttttctca agtgcaaatt
     4081 aacaacatag tccttgatag agaatttcta gaaagtgatg ttatctatat aaaatacgca
     4141 gatcaacaaa ttaggcaact agtcgatgcg tattatcaag cgtatgggaa actcatttct
     4201 agtgccatga atgtttacaa gcgctctaac gctcgtagat acgtactgaa agggaattta
     4261 ttccgaccgc aagacaatac aacacaagat caaatcaata aaatgatgac atcacaattt
     4321 aaggctttta tggaagctga taatgcaggt gcggtatttc aattacaaaa tgagtacaca
     4381 ttagaagatt tcagcggaaa cttccaaagc aattcaagag atataaaaaa cttaatagac
     4441 gacatctttg agatgacagc agcagcgttt cacgttccga aaaacctact aaagggagac
     4501 atgagtgggt tatcggatca agtggacgct tttttaatgt tcgaaatcat accgattgct
     4561 gaacttattc aggatgcgtt taacgctagt ctctatgaag tagaagaata cttgtcaggg
     4621 aattttgtac gtgtggatac aactatgatc aagattacta gcttcaaaga tttggttgac
     4681 gctattgatg taggcattag aaatggagta tttacaatca acgaaggaag agaacgcgtt
     4741 ggaaatgatc gctctgataa ggcgatggca gatgaaatat ttataactaa aaacaatcaa
     4801 caagtatcga aaggaggtga ggcgaatgac gacaatgaaa acatttctag cagtaaagaa
     4861 tgaaggcgca gtaccgcaaa tttttattca gggatttatt ggttctagtt ggttctttga
     4921 agggaatact gacaagggaa tcaaaaatat tttggatagt ctaggtgatc aagaagaaat
     4981 tgaagtagta attaattcaa acggtggaga cgtatttcaa gggattgcta ttgggaactt
     5041 acttaagtca aataaagcaa aagttaacgt tgtgattaac ggcttagccg ctagtgctgc
     5101 ttcaattatc gcaatggctg gcgatactat aaaaatctac aacaatgcac aattgatgat
     5161 tcaccgcgct tccacatacg gagaaggaaa tgtcgatgac ttccgtacga ttgctgacca
     5221 actggaatca attgataaat cggtaaaggc ttcatataaa acacgattca atggcacaga
     5281 tgaagcattg caagaacttc ttgaaaaaga atcgtttatg gatgcagaaa cagctttgag
     5341 ttatggattg gtcgatgaaa ttatcgatgc agaaaatagc tcaggtactg aagctaaaaa
     5401 agaacaaagc gttgaagaaa ttttgaatga cgttaaagaa aaaagagcag aaaaaattgc
     5461 tgcatttaca gcagcattaa ataaaacatt tggacaagga gatgtaaaat aatgacagtt
     5521 aaaaatttaa aaggtgtaac agctgcaagc gaccaattga tgaaagcttt taaagatggt
     5581 aacgaagaat cttttagcgc agctatggta agcttatcta aggaaattca ggataaaatt
     5641 ttagaagaag caacagcaaa aaatcaagat caattagtat taatgaaccg tggtcagcgt
     5701 gtattaacta cacaagaaac aaaattctat aacgaagtag tgaaaaacga aggttttgca
     5761 ggggtcgaag aattagtgcc agctactgta tttgaacgtg tatttgaaga tttagaacaa
     5821 tctcatccac tattgcaaaa aattactttt gttaacacaa ctggtgtaac agaatggatt
     5881 gtgtcacgtg gagtcaatcc agcatggtgg ggtaaacttt gcgaagctgt taaaaaagtt
     5941 ttagataatg gctttgatgt aattaacatg aagcagttca agctatcagg ttatattcct
     6001 gtatgtaagg caatgcttga tttaggtcca gtatggttag atcgttatgt ccgtactgtt
     6061 ttagtagaat cattgagaat tgcattagaa caagcaattg ttgatggtac tggtaaagat
     6121 atgccagtcg gaatgatgcg tgacatgagc aaacaaacta gcggagaata tgctgaaaaa
     6181 aaagcagaac ctattacagc tttagatgct gtaactatgg gcggtttgat ggcgcgacta
     6241 tcaaaattca atatcgaagg tgtgaatgat ccgatttatc gtaatgtgaa tccttctgat
     6301 gtggtcctaa ttgtgaatcc aactgattac tggtctaaag tattcccagc taagactgta
     6361 ctaactgcta atggagaata cgtacaagta ttgccagtac cagtttcaga tttgcagtca
     6421 acggctgtgc cagaaggaaa agcagttatt ggggtagcct cagattactt catgggtgta
     6481 ggatctacac taaaaattga agcttcagat gaataccatt ttgttgaaga cgaacgcatt
     6541 tatctagcta aacaatatgc aaacggtcaa cctaaacgta acgatagttt cattgtatta
     6601 gatattagcg ctttgggaac tactactaca actacaaaac caacaaccac aacaactaca
     6661 acacaagcgt aggtgatcag aatgaagtat attctttgtc agctggcaat caatcggttt
     6721 aaatgggagc ttgaagtttg tttaactaat ctgaagaaac taggaatcaa agatatcgta
     6781 ttgcttttca gcagacacga tgatcagatt cctatttttt ttgagaagga atatggtgtt
     6841 gaagttcatg tgtacgatga tctgcgggac gacaaagagt atattccttc gattaaacca
     6901 tatttatggt ggaaatattt agaagaagat cattcgcgtg aggacgaccg atatttctat
     6961 atcgattcgg atgtcatttt caataaaaga attaatttgc gcaaattgcc ttctaaagat
     7021 gatgtttggt attgtagcga ctgctgtagt tatctaagtc ttgattatat tagaagctgt
     7081 gaaaacggag aaaatattct aaaagatatg gcaaacattg taaatgttac agtagaatct
     7141 ttggaaacta taaacactaa ttcaggaggc gcacagtggg ttattaaccg tcctaaagcg
     7201 aattattgga aaaaggttta tctggattct aatcggctat atcgctacct tagagggcaa
     7261 aaaacaaata tacaaatctg gacagccgag atgtgggcac agctttggaa catgatgtat
     7321 ttcaatattg gtcctaaagt tcacgaggaa ttagactttt gttttgctac tgatccaata
     7381 gaaaaagtta aagaagtaaa aatcttacac aatgctggag taacaacaaa cgatgaagat
     7441 ttatttttca aagggagata cgtgacttct acgccttttg atgaagattt atcatttgta
     7501 aacaagaaaa aatgctctta cgcatatgtt aaagcaatta aggcggtggt tagatgacgc
     7561 ctgaacaagt gactgaagaa ttgctaatag ctgtgaagga taatatttac gttacctgga
     7621 acgaagaaga tgagtcaatt aaaaagatga tagctaaaaa tgctgtttat cttcaaagta
     7681 aagtgagtac aacactttct ttttctcctg aaagcttaga atacggattg ctaatcgaaa
     7741 gatgtagata cgactggaat cgtgctttag atgagtttga acaaaatttc gctagtgagt
     7801 tattaggttt cattcaacat tatgcgctac aagaatatat tgcaggtgat gtgaatggcg
     7861 aataatcgta gactcgaaga aacattcaac gatggttggt taaagatttt gacgcaaact
     7921 accaaaagaa atgaactagg aaaaaagatt ggtgtagaag atacagaaat cacttcttta
     7981 aaatttagaa atctttccat gagagatagt gatataacag ctatggatgc gatgggatcg
     8041 aaattaacta agaaagtaaa gactccattt catccaatcg ccaagaaatt taataaagat
     8101 caatatttta tcgtaatcga tagtatgcgt tacaacgtta tctatgccga ttacgataat
     8161 ttttatatct atttttatct tgaaagtgtg ggtgaatatg gtgattgata attctaaaga
     8221 aaaagaacgt ttaaataagc aaatttctgc tatcaaaact tccttagaag agcattttgg
     8281 cctcaaactc tttcaagact ccgtaggcga ggatgagcta cctgatgatt ttaattactt
     8341 cattctcgaa acaggagaaa tagaaatgat cactgagcca aaatatagcg tgggtcaaaa
     8401 tctatatcta actttctatt cagaaaatag agaagattta acaggagact cactagatat
     8461 tatttcattg attcaaaatc gttcgattcg ttttcagaga atggatccca atcatttaaa
     8521 actagagaac caagatcgct atatcgatca attggtattt acgtttagac gattattgaa
     8581 gagtgattgt catggctaaa aatagttggg agctaaaaat aaatggacat gatgaacttc
     8641 ttgtgcggat ggaacgctat tcaagcgaga gcgaacgact gattaacgaa gcattgaaat
     8701 caaaaggttc ggctattgca gtggatagga ttacagaaaa aattcctgtt tctgaagcag
     8761 atttaagaag agggcaccaa cacgcaaaaa atagtcgtcc acttaagact caatacatta
     8821 atttgggttt catcattaga cctacaagaa aatttgagta tttaaaatat cctgatttgg
     8881 ggataggtac ttctaaaaga aatcagccgg acgaatttat gagaagagga ttaggtcttg
     8941 cacttgatcc aattacagaa cttctgattc gtcaattcga taaattaaat aaataggggg
     9001 aacaacaatg gctaaaacaa aaactgtagt aacaacgttc gataacataa gtatcaaacg
     9061 aattgctttt aattttaaga acgcaggaaa tgcaatcgca acgaattgta atggacaatt
     9121 agatggcgaa acagaaatgc aaacggtggt taaaaaatgt ggagcgacag aagtaaaatc
     9181 aaaatctaaa ccaatcaata tgacggtaac aattactgca catgtaccga tggaagttta
     9241 tcgacgtttc aatgggttga aacaagatgg acgtattaaa ccaggcattt actcttacgg
     9301 tcctgattcc gtaggcgaag atttctcact tgctgcagag atcgtggatg acttcgaaga
     9361 aaatagaaag ttagttggta tgttagcatg cacttcgaat acaggattaa cattctctat
     9421 tgaaaatggt gcggatgaag tagctgcgtt agaactagaa acaaaagtta tgcaagatga
     9481 atttggtaaa ttttatcatg aagcaattgt tgcagaactt gaagaagact taacagatca
     9541 atggatgacg aatctatctg ctgatgtgat taaaaaaact tcagttgtga caactacggc
     9601 cactcaatca cagtaaaaaa aacggaggta gcgaaatgaa cgaagattac tcaaaaattg
     9661 aactaaacga tggaacaatt ttgaatttag aacctaaact gaatatcaag aaattattga
     9721 tgatcaatag agattttaac acagacgagt ttgcaaaaat gactgtggga aaaggatcca
     9781 tggatatttc tgttattcaa ggtgcaaagg ctgtgtatat tgcttaccgc caagcgaaca
     9841 tgactgatta tatttcattc gatgaattta tcgataaatg ggattttgat atggctactg
     9901 ccagctatat ttatcaattg atgatgttca aacaagcacg cgatgcttat caaaaagaat
     9961 ttgaaaaagc aaataaggaa aaaaagcttc aaaagtaaaa attccaaagc tcttagttga
    10021 aacgtgggtc gatgtctatt cgatgttgac cgacgttttt tctatgcctt cagatttggt
    10081 tttaagcgat atctgtttag atgacatttt gcaaatggct tacaacaaga gtgcttatga
    10141 aggatggaaa aactatgcaa taaaccaatc ccagaaaaac taaagaaagg aggtaaaaaa
    10201 tggctaaaaa gagaacagaa gcagaagtaa ctttcatagc taacgatgac ggattgaaat
    10261 ctacgttaaa agaaatcagt gctgaattaa ctaaaaatag agcagaatta aaactagaac
    10321 aagctcaatt acaacagact ggttctgaat cagacaagtt aggaagtaaa ttatcttctt
    10381 tagaaaagca gtatgaatta caaagtcaaa aagttgaagt aactagccaa cgtttagcca
    10441 atgcgaaaaa atattatgga gaaaattcca ccgaagttca gaaacttgaa agagaactga
    10501 ttaatcaaca aacagcgcaa caacgtttgt caaacgaaat tgataaaacg agtaatgcac
    10561 tagctcaagc aaaaggcgaa atacagacgt acgagtctac aatgcaacag ttggatagcg
    10621 aacaaaaaaa tgttcaagct agtgcttctc tgattgaatc cgaatacaaa aaatggcaag
    10681 caactgctgg tcaatcagct tctgaagccg agaaattagc gaaagcccaa gaatatgttt
    10741 ctcaacaatc tgaaaatgcg gagaaaacga tagatatcct aagacgacag ttagaagcta
    10801 cacagtctga atttggcgct acatccacag aagcaatgca gatggaagcg aagcttaatg
    10861 atgctgaacg tgaatttgaa gagttaggac aagctgctaa aaatgtagat acaactaact
    10921 tggacgatat cggaagcaaa atagatatga ataatttaat ggaagcttct gacgttttaa
    10981 gcgacattgg cgataagctt acagaattag ggaaacaagc agtggactct gctaacagtg
    11041 taggtagttc ccagagtaag atacaagcta attttggttt gtctaaacaa gaggctgaag
    11101 aattaacgaa tgtagccaga gacatttatt ataaaggttt tggagaatcg ttagatcagt
    11161 ccacagatgc attgattttg gtaaagcgta atttaggaga tttaaataat caagatttac
    11221 aaaatatcac ggaacaagct atggtcctag aaaacaccat gggcgctgat atggatgaaa
    11281 cgttacgtgg tgtaaatggc ttaatggtca atttcggctt gagtgctcaa gatgcaatgg
    11341 atttaatggt ttcgggtact caaaacggtt tagataaaac gcacgaatta ggcgacaata
    11401 tggcagaata tagccaatta tggagtcaaa tgggatattc agctgatgaa acgttcggaa
    11461 tgcttcaaaa tggtttagat gcgggtgctt ataaccttga taaagtcaat gacttagtta
    11521 aggaaatggg aatatcgtta acagatggtc gatttgagcg aaacatggat atgtttagtg
    11581 aaagtactag aaaagctttt gaagagtgga aaaatggcgg aggaacacaa aaagacgtta
    11641 ttaattccat gattcaagat tttagcaata tggatggtca atacgaccaa ttaaataaag
    11701 cttctacaat ttggtctgca cttggcgaag ataacgcgat gaaagttgtc caatctttga
    11761 ctgatgttaa ccatacattt gatgatgtta gtggatctgc acaaaaaatg aatgaagatt
    11821 ctactactcc gttacaagag ttgaacggga aaatagctga attaaaggat tcattagctc
    11881 ctataggcaa cacaatcata gatgcactcg aaccagtaat tgattttcta ggaaagatgg
    11941 ctgatgcgtt taatagtctt ccacaaccag tacaggatta tgccgtagcg attggcggat
    12001 tgactgctgc atttacttta ttaatgccaa taatagttgg cttcatggct ctaggtggtc
    12061 ctactacatt aataatagga gcagttatta ctgctattgc tggagttata gcaattataa
    12121 aaaactgggg cgcaattact gactggttta agggaatatg gagtaaattc actgattggt
    12181 tgggtggtac ttgggaaagc ataaaagaag gtgcctcatc agtttgggat ggagtcaaag
    12241 aaacctggtc tggatttgta gattgggttc aagaaatttg gcaaggagtt tctgattggt
    12301 ttggagagtt atggagcgga ttagttgaag gagcttccaa catctggcaa ggagtccaag
    12361 agacttggca agcattcgtt gattgggttt caaatatttg gaacggagtc aaagaagtat
    12421 ggtcgattat ttgggcagac attgtaggaa ttgttcaaat accatggaca ttaataacgt
    12481 cattgattca agctggtatt aatattatcg tgggtatctt tgatgtagct ggacagttat
    12541 taggcgcagc ttggcaagct gtttggacac ctatttctga tttccttaaa aatacttggg
    12601 atactatgac acaatggata agcatcgctt ggaatggaat tgtaactaca ttccatacta
    12661 tatttgatcc agtagtggca tggtggaatg gtatatggac atctattagt actacggttt
    12721 caaatatttg gaattcaatt agtgcaacag cttctagtat ttggaacagt atcaagaata
    12781 caatcactag cttggtacaa gcagctgcta cagtaattca aaatatttgg tcaactgtat
    12841 ctagttggtt aggtggaatt tggaattcaa tcagctctac agcatcaaat atctggaata
    12901 gtgtgactag tagtataagc aatgctataa acgcagctaa aagtgccatt caaagtgttt
    12961 ggaatagtat atcttcgtgg atcagcggaa tttggaacgg tatcaaaaac actgctttga
    13021 atctttggaa tggaattaca agcactatta gctctaaagt aaacgatgga aaaaatgcaa
    13081 tttcaagcgg ttggtcaaac ctaacaggta ttgtttccgg catattcaat aatgttaaaa
    13141 gtacgattgc taatatatgg gaaggtatca aaaagactgt tagcgctccg attgattgga
    13201 ttagagataa aatcagtagt gtctttgata atttgaatat ttcgatacca catattccgt
    13261 taccacattt taaattgagc ggagaattca atccattgaa ggggaaaatc ccaacattgg
    13321 gtgttgattg gtatgcgaaa ggtagtgtgt ttaattctcc aaatattatc ggtgtcggtg
    13381 aagcaggacc tgaagcagtt ttacctttga aaagatctgt gctgcaagaa attggggatc
    13441 gtatcttgag tagcacctca gtttcatcta gggcacaaac gattcaacct gtgaacaatt
    13501 acgaattcaa tttcacaatt gatggtaacg cagatgaggt tactatgaag caaacaactc
    13561 aacaaatcat tgatagcatt acaaaaattc aaaatgataa tgcttcggca tggcgttaaa
    13621 caggagagta tttctcctgt ttttttagta ttaaaaagga tgtgaaaaaa tgactgattg
    13681 tatacattct ataatcgatg gatttcctga ttatttgcat aaattggctt tagctgaaag
    13741 accaaccata ccttctccaa aaagacagag agttgaaact tctgttttag gtaggttagg
    13801 tggcttagta caagattact cgtttgaaga tatgtcgttt acattgcact ataactattt
    13861 agaggatgtg gaagaccatc aagcgttcaa gcaatcgttt tatatcatgc gtcattggtt
    13921 aaactatgca aagaaattag aattctctga cgatcccaac gtctattacg ttatccagac
    13981 tatcgatatt ggggatgcag aaaacgatat tgttgaatgg ggagagttcg atgtaaatat
    14041 tactgcgaaa ccattcgcaa gagttcaaga agatgtacct ataaccgtag ataaaccaca
    14101 gtcatttaac ttgctgaata atagtttaga agaaagtttt ccaaagatta tcatcactcc
    14161 ttcagctact tcatgccagt tcatcttaaa tgattatgtg tttagtttcg aaggcttagt
    14221 agcaggaact gatgtagtca ttgatagtga tttgatgctt tgctacgaag agcaatcgga
    14281 cggagatatt ttagatcggt ccaacaaaat gaagaccatg caatatccga cattgcaagt
    14341 ggatatcaat cattttaatt gcactggttt gagcaaaata caaatttatc gtaacgggtt
    14401 aaggtaggtg aaatagatga tcgataattt aataactatt tacgataaaa atgacgcgaa
    14461 taatttagct gaacatttat atgatacgca aggtttaggc gctttgtcag actggttaac
    14521 agctactgtt agcaataaac taaacggagc cgagatattt cagggtactt attcaataaa
    14581 cggaactaat gcagatttga ttgtagaagg acgtattatt cagtgttatg tagatgaaaa
    14641 tcgagcaaaa cagcgtctac ggatttatta tgcaaaaact tctgtaatag gcaatacgat
    14701 agaagtaaaa gctgaaccta ttttcaatga tataagaaaa tcggtgttga ataaatatga
    14761 cagcggaaca gaaaagatca ctgctactca ggcatggcaa aacgcaaaag ttttagcgaa
    14821 accagctatc ccttcgcagt tttctttctc gtcattagta gatacgcttg ctaatgtgaa
    14881 gatagaaaag gcgaattttt tagaattctt tggtggaaaa gagggatcta ttctagatcg
    14941 atttcatggt gagtttctaa aagataataa cacattacgt catgaaaaaa gtctaggtac
    15001 ggatcataaa atcaaagcga tttatactaa aaacttaact ggtcttgact tagagattga
    15061 tgctcaaagt gttttagttg gagtttatcc attcattagc agctcttcag aaggagaaga
    15121 cgagatcact ctaccagaag aagttatttt cacggattac gtggatgatt atcctgctgg
    15181 atatgtttct tttgttgatt ttaaagacaa agcgactgat gtagccacat taagggaagc
    15241 tgctaaagac tggttgaaaa caaacataga taaacaaaaa ccacaagtga gtggttcgat
    15301 tgaattagta ccattgaggc atcaaagagg ctatgaaaaa tttgttgatc tagaaaaagt
    15361 ttcgatgggt gacggagtag atgtgtatca tccacagtta aaagtgaata tgtcagcgag
    15421 aattgtggaa tatacgttta atgttctaac caattcatac gataaattag ttgtaggaaa
    15481 cgtcaaaaca aacttcttag aaaacacaga gaataatgtc agcaatttga ttaatgatgc
    15541 cattgatcaa ttgaaaaacg gtggcgaaat cagtgattta ctcaatgata ttgtagatca
    15601 tcaaactgat atgattactg gtcaaaatgg tggttatgtt ttattagatc ctaaagaagc
    15661 gcctagtcgt attttgatta tggacacacc agataagaat accgcaagga atgttttaca
    15721 aatcaacaat gctggtattg gtttttctaa aactggcatt aatggaacat atgaaacggc
    15781 atggacgtta gatggcggat tcaatgcctc gtttattacg gctggtgaaa tagtaggaat
    15841 tactattaga ggtactacat taattagtga tggtgctgat tatagaacaa gtattgctaa
    15901 tggcaaaatg acttggtact caaaaaaagt taacaaagat attatggagc tagaagcacg
    15961 tgattatgta agtgctgatg ccggtattgt atcatacacc atgaaaactg gtggtggttt
    16021 catgattaga aatccacagg gtaacttggt ttttagtacg tgggataatg gtaataacag
    16081 accgtttcta tcttttggtg cgcccaattt caggtatagc aatgctagtt atgtaacttc
    16141 tggcgacggt agttctttaa gcattaatgg tagtgcgggt aactcatggg aatttaaggt
    16201 agctggtagg actatgaaat ttactagtga tggtatgcta acgttaccag gttgtttttt
    16261 tggttcatgg gaagatggga aacttgctag gtttgaacaa tcaacggtac aagtatataa
    16321 agattttact gttagaggta ctaaaaactc aactgtacca acagaacatt atggacaacg
    16381 actattgaac gcttatgaaa ctccagaata ttatttcgct gattatgggg aagccgttac
    16441 aggtgacaat ggtaaagttc gtgttgatat tgaccccatg tttgctgaaa cagtaaatct
    16501 aagtcggtat atgacacatg tgacacctac agaactagtt ttgtgtgctg ttactcatga
    16561 agatattgac catttcatca ttgaaactag taagccaaac gtattagtta gatggaattt
    16621 agtggcacac cgtctagggt atgaagatat tagattaaaa gaggatacag catatgatag
    16681 cacagtgctt gaccaaaaac gtttttaaaa cgaagacaag gaggtatata aatggctagc
    16741 agtttatata atttggcttt agatttcagc aaagaattaa actacaccaa agctattatg
    16801 gctcgtcaag gtgataaagg gattacggtg acggttaaac cgtttctaaa tggcttgcag
    16861 atggatacga gtggcggaac atttacttta aaaggaacaa caccatctaa ccgttacgta
    16921 gataatgttg caactagtgt aactagtgaa gaagtcacgt tttctcttga tggcacattt
    16981 atgagtgaag caggatatta taaacactgc tacgtagaat atagaaaaga caatcaaatt
    17041 ttaacaacgc aagatatcat ttttttctca ctaggagtgt ctgacatttc gcaaggccaa
    17101 gccgatgaat atgtttcgca attagaagag ttgattcgaa agtacaacga aacttttgat
    17161 gcttttatgg ctgaaatcaa aggtagagtg gatagcttaa atcaacagat tactgattta
    17221 actggtcaag ctaaaacgct acaagacaag ttagatgctc tgaaagaaga aatttctaag
    17281 ttaggtaact tacaagtgat gtacagtaac agcatcgact tcgggaatta tgattatagt
    17341 gggaatccga atttaatgtc caaactaaaa tcgagcgatt ttaacgttgg ttaccacggg
    17401 tcactaactt cggataacga aaagctacat tttacttctg atggtacagg aagcattatt
    17461 atgtttacgc gtattaatac acctcagctt gctagtggga aaacctatac tctgagtgcg
    17521 aaagttcgat ttgatgaagg aactacagga gctattgata aattacgttt ggtgtatcgt
    17581 acatcaccag gagaaaagat attattggaa gcaaatagta caaatattac aacagatgat
    17641 gtagggaaag aaataacaat caaaggtaca gctaacgtta attatcaaat cacaaattta
    17701 gatcgatttt atatgagtat tagctttgtt gacagggata aaataaatgg cggatttaag
    17761 ttgtacgaca tcaaaatcga agaaggctca acagccaccc catatcagcc aaacttacta
    17821 gatggccctt actggttagg taaagttcct ttaggcgaga atattgctga ccctacagtt
    17881 gtctttccac acaaaactag tgaatatatg gtttatggta gacgcaatac agaaaactat
    17941 atcgctgacc aaacatatac catatcaatg aaagcaacta aactaacagt tcaatcgttt
    18001 gccgtgtata ttgctgctgg ccgcgttaaa gtaggagaca tgaagcctac tgaggggtta
    18061 gctaatacat gggagttaac ttttactgta actaagcaac atatagatag tggggtaact
    18121 aattatctgg aaatatacca atacccgtca gctacaaaag gagctgttca aattgagtgg
    18181 ctcaaactag aaaaaggcaa tactcgaacc ccgaatatta gtgagtataa atatcgtggt
    18241 actggtatgc gtgattcaaa caatccaaaa gattatgttt gggatctagc accagaatat
    18301 gtcgaagata atttggccac agatattaaa atttctgaaa ttactggtaa agcaaacaat
    18361 tataccgatg ggaaagtatc ggagattaat tcgcagttga ctgcttcaat taatgaagta
    18421 gacaccacag ctaaggatgc tcaaacaaaa gcgaatgcta atgcgactgc tatagatgaa
    18481 ttagacaata agatcgatga acgcattaat gatacagcta ctaccacatt aacagttaca
    18541 aacgggaata ccggatcagc aaagctttat cgtgaaggaa aaacagtttc tatatatttt
    18601 gtggctttaa acggaaaaag cagtggtgga aatgattcaa cgatactaac aattccagaa
    18661 ggctatcggc caccaattag ttttgagcaa ctggttggct c
//
LOCUS       DAZKPE010000051        18000 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000051 DAZKPE010000000
VERSION     DAZKPE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.051"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..327)
                     /locus_tag="ACG930_002000"
     CDS             complement(52..327)
                     /locus_tag="ACG930_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFQ0519156.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(570..1880)
                     /gene="der"
                     /locus_tag="ACG930_002001"
     CDS             complement(570..1880)
                     /gene="der"
                     /locus_tag="ACG930_002001"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFQ0519157.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2062..3291)
                     /gene="rpsA"
                     /locus_tag="ACG930_002002"
     CDS             complement(2062..3291)
                     /gene="rpsA"
                     /locus_tag="ACG930_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFQ0519158.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3426..4106)
                     /gene="cmk"
                     /locus_tag="ACG930_002003"
     CDS             complement(3426..4106)
                     /gene="cmk"
                     /locus_tag="ACG930_002003"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFQ0519159.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTREVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4155..4790)
                     /locus_tag="ACG930_002004"
     CDS             complement(4155..4790)
                     /locus_tag="ACG930_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFQ0519160.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4856..6259)
                     /locus_tag="ACG930_002005"
     CDS             complement(4856..6259)
                     /locus_tag="ACG930_002005"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFQ0519161.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6246..7277)
                     /locus_tag="ACG930_002006"
     CDS             complement(6246..7277)
                     /locus_tag="ACG930_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519162.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7308..7529
                     /locus_tag="ACG930_002007"
     CDS             7308..7529
                     /locus_tag="ACG930_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFQ0519163.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7694..8431)
                     /locus_tag="ACG930_002008"
     CDS             complement(7694..8431)
                     /locus_tag="ACG930_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFQ0519164.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8584..9924)
                     /locus_tag="ACG930_002009"
     CDS             complement(8584..9924)
                     /locus_tag="ACG930_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0519165.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10161..11684)
                     /locus_tag="ACG930_002010"
     CDS             complement(10161..11684)
                     /locus_tag="ACG930_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFQ0519166.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFELLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12062..12673)
                     /locus_tag="ACG930_002011"
     CDS             complement(12062..12673)
                     /locus_tag="ACG930_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0519167.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12796..12921)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13003..13719)
                     /locus_tag="ACG930_002012"
     CDS             complement(13003..13719)
                     /locus_tag="ACG930_002012"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFQ0519168.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13725..14294)
                     /gene="scpB"
                     /locus_tag="ACG930_002013"
     CDS             complement(13725..14294)
                     /gene="scpB"
                     /locus_tag="ACG930_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFQ0519169.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14278..15048)
                     /locus_tag="ACG930_002014"
     CDS             complement(14278..15048)
                     /locus_tag="ACG930_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFQ0519170.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15045..15416)
                     /locus_tag="ACG930_002015"
     CDS             complement(15045..15416)
                     /locus_tag="ACG930_002015"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0519171.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15435..16322)
                     /gene="xerD"
                     /locus_tag="ACG930_002016"
     CDS             complement(15435..16322)
                     /gene="xerD"
                     /locus_tag="ACG930_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFQ0519172.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(16418..16891)
                     /locus_tag="ACG930_002017"
     CDS             complement(16418..16891)
                     /locus_tag="ACG930_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0519173.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHNHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(16996..17859)
                     /locus_tag="ACG930_002018"
     CDS             complement(16996..17859)
                     /locus_tag="ACG930_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFQ0519174.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
BASE COUNT         5065 a         3879 c         3028 g         6028 t
ORIGIN      
        1 aaaaagaaaa gcacttgtag ccctagagcc acaagcgctt tttcaactgt cttatttaac
       61 agcgtctttt aatgctttac ctggtttgaa tgcaggtact ttgctagctg gaatttcgat
      121 ttcttcacca gtttgtgggt tacgaccttt gcgagctgcg cgttcgcgaa cttcaaagtt
      181 accaaaaccg attaattgaa ctttttcgcc gttagctaaa gcatcttgaa tagttgaaaa
      241 tacagcatct actgctgcag ttgcatcttt tttagttaaa tcagtagctg aagcaacttt
      301 ttcgattaat tctgctttgt ttgccatgga tagattcacc tcctccacaa gagatatgat
      361 agaaatatca tttagttaaa actttctgag tggtccagaa gtttaaaaag aaatattgat
      421 taacttcaat attctgttat cacgatatca tatgaaccgc ttaatagcaa ggtttttacc
      481 aattttcaca tgcttttttt agtcatagaa acgtaacaaa cgaaactgtc tttttctttt
      541 gaaaaaaaaa cgtcgatatg gtaaaatgcc tattttctcc tacgagggat aattcggatg
      601 gacgtccctt caaaagtaaa tgcttttctg atttgatttt ctaagaaacg ttcataagaa
      661 aaatgcatca attcctcttc attgacaaaa acgacaaatg taggtggttt gacagcgact
      721 tgtgtagcat aaaaaatctt caggcgtttt cctttatctg ttggtgttgg attgattgct
      781 acagcatcca taatgatatc attcaacaca gccgaagaga tacgaagatt ctggttcata
      841 cttacttgtt cgatcatttc aggcagacgt tccaaccgtt gtttagtcac tgcagaaaca
      901 aaaacgattg gagcgtaatc aagataccgg aattcatcac gaatctcttg ttcgaaatca
      961 cgcattgtat tggtttcttt ctttacaaga tcccatttat tcacgacgat aataattcca
     1021 cgaccagctt catgggcgta acccgctact cgcttgtctt gttcccgaat cccttcttca
     1081 gcattcagta ccatcaaaac gatatcagaa cggtcaatgg cacgcattgc acgcatcacg
     1141 ctgtattttt cagtattttc gtatactttt ccgcgtttac gcataccagc tgtatctatc
     1201 attaagaatt tctgaccact ttcagaaacg aagtgggtgt cgattgcgtc tcgggtcgtt
     1261 ccttcaatat ccgaaacaat tacacgttct tctcctaaaa tcgcattgat caaagaggat
     1321 ttaccaacat ttgggcgacc aatcaaacta aacttaatcg tgtcgtcgtc ctcttcttca
     1381 gtctcttcag agaaatactt cactgcttca tctaaaatat caccaatccc tagtccatgg
     1441 cttcctgaaa caggataagg atcgcctagc cctaaggaat aaaattcata gatatcgttt
     1501 ctcatttctg gattatctac tttattgact gctaaaatca ctggtttatt acttctgtat
     1561 aaaattttcg caaccatctc atctgcgtct gtcacgcctt cgcgtccgct gactacacaa
     1621 atgattacat ctgcttcttc aatcgcgatt tctgcttgat gcttgatctg atccataaaa
     1681 ggttcatcgc caagatcaat tccgcctgtg tcgatcacgc tgaattctcg acctaaccat
     1741 tcaccttttg cataaatacg atcacgagtt actccaggag tatcttcgac aatcgagata
     1801 cgctcaccag cgatgcggtt aaaaatcgta gacttaccga cgttcgggcg gccaacgatt
     1861 gcaattgttg gatttgccat attatttcct cctcacaagt ttccaatctc acttagttta
     1921 acgaatgcat tgccaacttt caagcataga ttgtcaatta aacgaagtat ttttattcct
     1981 tattgaaata ctaatcgctt ttcaaaagaa aaactgagac aaaagcagct gctttcatct
     2041 cagtcacaga tacaaaatca attatttttc agaatcatcg gttgcttttt cttctacttc
     2101 ttctttcaac gcatcaccta aaatgtctcc catagtaaat ccagtatttt cttctggtaa
     2161 ttcataagac tcaacatttt ttggttcttc ttctgaagct ggtttttctt ctaaagcttt
     2221 gatactcaat gcaatacgat gttcttctgg atggatctct aatactttca ctttcacttc
     2281 gtcaccttca tgaagcactt catgtggtgt cgcaatatgt ttatgtgaaa tttgagagat
     2341 atggactagc ccttctactc cagggaacac ttcaacaaag gcaccgaagc ttgtcaaacg
     2401 tttaactgtt ccgtctaata ctgtgccaac tggagctttt gtatcgattt ctgaccaagg
     2461 tccaggctgt gtgtctttga ttgacaagga aacacgttct tgttcaggat tgatagacaa
     2521 cactttgaca tttacatcat cattgacagc caatacatca cttggttttg ctacatgact
     2581 atgtgaaatc tctgagacat ggactagacc gtcaattccg cctaggtcga caaatgcgcc
     2641 aaaatcagta agacgtgcaa cacgtccact gagaacatct ccctcatgga tagttgaaag
     2701 aatttctttt ttcttttctt ctctttcgtt ttccactacc gctttatgcg ataagatcaa
     2761 acgattttct gatggttcga tttcgatgat tttaaagctc aatgttttgc ctttatagtc
     2821 tgaaaagtct gcaacaaaat gatcttccac cattgatgca gggacaaaac cacgtacacc
     2881 gacgtcaacg actaaaccgc ctttgacaac atttgtaaca ggtgcttcga tgaccttgcc
     2941 ctcttggaaa tctctttcga tatcttccca aactttttta gcatctaaac ggcgttttga
     3001 aagtagatag ctgccgtttt ctttatcttt gccgatcgta ctgataacga ctaaatctaa
     3061 tacatcaccg acttttacta cttcgctgat atcttctacc ggcaaagttg ataattcttt
     3121 tgccggaacg actccttcaa ctccagcccc ttcgattccg acaatcactt gtttgtcttc
     3181 aatgactaaa acttcgccct taacaacatc gccaactttt acttcttgta cgcttttcat
     3241 tgcgtcttcc attgactggt tgttctcttg attttgatca aattctgtca taacacttgt
     3301 cctcctaacc aacattctgc cgtaagtacg gtactgtttt tagtttaatt gattattcaa
     3361 aaaaaataaa gcgatttcgt tcgttttcct tgaaaaaaca attgtttttc attttttttc
     3421 ttaatttaaa aaagaagata accttttttc aaaacaacag cttttattgc tgcaacgact
     3481 tctggaatcg atttgccagt cgtatcgata cgaacagcat cctctgcttg cttcagcgga
     3541 gagacttccc ttgttgaatc ataatggtct ctttcctgta tctctttcgt cagtgtttca
     3601 agatcagtcg gaattccttt ttcttggttc tctttgaaac gtctttctgc acgctcactt
     3661 acgcttgcta ctaaaaagat tttcacttct gcattcggta atacagctgt cccgatgtct
     3721 cttccgtcca tgacaacgcc accgcgttcc cctatttttc gttggacagc aactaattct
     3781 tctctgactt ttccatgtgc agagacttca gaaacagctt ttgtgacatc tggttgacgg
     3841 atttctaaag tcacatcttt tgatgctatg aatacatgct gtccatcttc ttgttgcgaa
     3901 aaagagatag gatacttttt gatcagcgaa actagccctt cttcatctga aaaagataca
     3961 ttgttcgtaa tagctaaata agttactgcg cgatacatgg caccggtatc tgtataaata
     4021 taattcaatt cttttgctaa tatcttggca acggtacttt tcccagatga agcaggcccg
     4081 tcgattgcaa tactgatttg tgtcatgata taactccttt ttctcagaaa aaaagccgca
     4141 aagcgcggct attattattt aattcttaat tcttgaccag ggtaaagcat aaagttgttt
     4201 ggatctaagc cattcaattc aaacaattga tcagtggtga tccctgcacg ctcagccact
     4261 tgttttggac cttcgcctgc ttgaacagtc gttgttgaac cggctgcagc tgatgaagaa
     4321 ggtgttgttt ctgctgcatt gctgcttgaa tcccctgctt gataagttgc ctcacttgag
     4381 gaagtcggtg ttgtctctgc tgcaatactg ctttctgacg ttacacctgt atcttgagac
     4441 acagtagatt cttccgcgat tgtactagat tctactgttg aagtctcagt tgactcctct
     4501 tttgttgtac ttgtagaact ttctactact gatgtcgaag tttcagaaga agttgctgct
     4561 gttgcattgt tgcttgatcc atttctgatc cagaaataag cacctgctgg aatagcgata
     4621 cataagacca gtaaaatcaa aaatagcgaa agaaataatg tatttccttt cttttgttgt
     4681 ctctgagaac ttcttgatga aacttcatca tctgtatcgt agattggttg ttcccatggt
     4741 tcttgtgttt cgttattttc tgtagattga tgtctatctt ttctgctcac tgttttacct
     4801 cctaaactct atcgtgtgta ttataccata ggaaaaagtg tcttgtccta aaaaatcaat
     4861 gttccatgtt ttttttaaat aaatttagta aaatcgtttc ccaatgaagt tgttcagtct
     4921 tagaaaaaag cttcctcttt ggcagaagtt ctgcttttgc tccatcaata tcacaacaat
     4981 tctgcggctt ttcggagagt ttttcgccaa aataagctaa gatgaatttt ctgcggcagt
     5041 tttcttcatt aatatagcga agcatctgct gcaggcggaa ttctttttct ttttcctgac
     5101 gtttgagccg ttccacccaa ttttctggtt tttcagactg ctggatcagc tccatccatt
     5161 ttttttgcag ctcatcaaag ggagcttgct ctgtggcata ttccaaataa agctcaaaac
     5221 tttgtcgctg ttctctagaa agttgattaa agaaataatg gatacgttca tccccacttt
     5281 gataaaaaag aattgctgca ctttcttcct gatctctgcc tgctcgaccg atttcttgta
     5341 catagttttc tagactgtct ggcaaatcat aatggaccac ataacggata tcagatttat
     5401 cgatccccat accaaatgca ttcgtagcaa tgagaaactg cagctgattt tttacaaact
     5461 gctgttgaag ttgtcttctt tgagctgcat caagaccacc gtgatagtat ccaactgtaa
     5521 aacgttccct gaataaatga tacaatcgtt cgacttcttt ttttgttgca caataaatga
     5581 ttgccgctcc ttgtgctctt tccatgaagt gttcaagttc ttgttctttt tgctgcgttt
     5641 tccgaacaaa aagcgagata ttttgccgat tgactgattg tctgatctct tttggtggtc
     5701 gatcaaatag tacatgacgt atatctcttg ctactaaatc tgttgctgtc gccgttagtg
     5761 ccagtgtgac cgggtttcct aaaagctttc ggatttttcc taactgttga tattctggac
     5821 ggaaatcaac tccccattga gacacgcaat gagcctcatc tactacatat aacgcaatat
     5881 tttgtttttt cagatgctct aaaagagaag gattagtcaa catttcggga ctcaaaaaca
     5941 aaaatttata ttgcgataga tgacggagga cgtatcttct ttcagattgc gaaagtaaac
     6001 tattgaaagc agctactcgt ttctcccctc gtttttgtaa ttgcgtcact tgatcttcca
     6061 ttagagaaag cagcggtgac acgatgatga ccagaccttc cattaaatac cccgtcaatt
     6121 gatagcaaag gctttttccc gttcctgtag gcaaaatagc gagagtatct tctccatcaa
     6181 gcaacgcctg aataatttct tcttggccgg gacgaaatga atcaaatcca aaatattttt
     6241 ttaattcatt tattaacatt ctgtatcgct tcctttctca atagatagat ttgatacaaa
     6301 cgaaattctc cataatctaa ttgtccatct acattccatt cgctaaagcg ccactctcgc
     6361 acggaatcct tatttggttc caaacgttcg attgtttctg cagagagaat ccactcgtat
     6421 ggaaaatcat caaaaaacaa ggcccactca ataagatgat ctgttactgt tcctcttttt
     6481 aaatgacgga ttgccatgat ctggtcaatt gtctgaccat tcataaacat ctgcttggtg
     6541 atcatcatgc tttgattgaa attttgctgt aataatgaat cgatcaaagc gtgccaaagc
     6601 gaatctggcc gtttttcgat ttgtgctaac aaaaggtgga tacatctgct ttgttgcaga
     6661 taaaccgctg actcatcatt gttttttgcc agctgataag gaagcagccc tgttcgctca
     6721 tttccagata attggttagc taaaaaatct gctgcttctt ctggtatctc cgaaaacagc
     6781 tgcaccaaac tctcatacgc agtatcaatc aaaatttcac gtggcaattg gctttcacta
     6841 agccattttt ttagttggaa agtataaaaa ggacttgtct ctgctggaag atagtcttga
     6901 atacccgttg ccagattaga aattacttga acagcaaatt taatgagccg ccaactagtt
     6961 tcccctgttc tgccatagcg gtcaaaacgc aaaccagtat gttctatttg atgttcggac
     7021 aacatatcag cccctgcagg cgttagcttt gcttcatttt catttatttc gatccaacct
     7081 tgctgcgcaa ttttttgcaa aatttgataa aacttatcct gcttcaattc tggaaaactg
     7141 ttatggataa acaaaagttc gtgggtaaat ccataaataa gtactgaagt cgttcgtttt
     7201 cccacaagga gttggtaaag agaactaatc cgcagcttgt gtcctgatga aaatagcgat
     7261 aaaataaaaa caatcatatt attctcctta agttaggatg gttagaaatg tcactactat
     7321 gtaaacttgt acctgaacgc tgtattgcat gcggtctttg tcaaatcgaa gcgccagata
     7381 ttttcgatta tgatgaagaa ggaatcgttt tatttgccca agaaccagag gctcatcaac
     7441 agttcgtgat gccggaagaa gaaacatatg taaaaaaagc gtatcaaaaa tgtccagttc
     7501 gagcgatttt attagaaaat aaaatataaa tataaacgaa actttaaaaa cgtacactaa
     7561 gttctctaaa cttgaaaata agccgggatc tgtttctctt gttccgtgaa atcccgactt
     7621 attttgaaag attcatttgc tatctatagt taattgacta gttttttcac ggaccctata
     7681 ggacccattt atattatttc aactttttca gccagttttc caatgtattg acgatcacag
     7741 tttgctggtc tgcgttagaa atttctgcct ctccatctcc tttttgctca ccatagctgc
     7801 caaaacctcc atgatttccg ccattgattg atacatactc tgttctttcc ggtaaatact
     7861 gcttagcttc ttgataagct tcctgattca atactttatc ttttgtcgcc gtgatcgata
     7921 aaacaggaac agctgattct gtcaatgttc cttttttgtc gggataactt gccatgaaga
     7981 ataccccttt taaatgtttg tctgaatgat tcttattgac ataacgactt gccattacgc
     8041 cacctaatga atggccaccg atcacataat cggaatttgg aaaatcttct ttgaccttat
     8101 ccgctttgtt tccgcccatc actgctagat caagtggcat tttgacaata gcgactgaaa
     8161 agccgttttt tgctaaatct tgcgcccaaa tactataact ttctggctct acgagagcac
     8221 caggataaaa aataagtaat ggagactttc catgattctt tttctctcct tcaaaaaata
     8281 agtaatcttc tttgtttttt ccttctttta ccaacacttg cgcttctgac gatggttcgt
     8341 acgtattttg ctgtatatag taataaccgg ctccaccgag taatcctaaa atgatgacta
     8401 agccaattag tattcgtcta aatattttca ctttctccca ccttttctat ctgagtgacc
     8461 cctttttctt aatcaagtat gattatacct taaaaaaata agagagaaat gcaaactttc
     8521 cagcatcaaa taaaaaaaga cggaatatcc atttgaatat ccgccctttt tgtatgttta
     8581 tttttattta gcacataaac gatacacagc ttctgcataa atttccattg ctttatacat
     8641 actacttaat tcccatcgtt cattcgcctg gtgcataaag tcaggagtat cagggaacat
     8701 cgcaccgaat gccacacact ggttcatcgt acgagcaaaa gtagcgccgc ctgatacaaa
     8761 cggttcagtc atgtctccag taatatcgcg atatgtcccc aatagatttt tcactaactc
     8821 actgtctagt ggcacgtata atgaatcaag gaagtcaaat tcttcataag tcaacccata
     8881 tttttctgct gttttagtta atttagctac taaatcatct ttcttgaatg taacagggat
     8941 tctcatatct acaccgattt ttgtttgttc tggtgtgatt tccaaacttg caaagttcat
     9001 cgttagctcg ccggattgtt catcttctgt tttgcccacg acagcttcac cagttgcatt
     9061 ttcttgaact aattttccta agaaattgat tgggccaaaa tcaaatactt ctgaaagagc
     9121 aattgccaga cgagaaatag cattcactcc ttgtgctgca tctttcgcgt ggatactttt
     9181 accaagaacg acgatgcctt caccttgttc ttcgaaatcg aattcgtgtt ttttcaatgc
     9241 ttcttttact tcagaaagct tttctccaga gtaaggagct gcatcaggaa caacattcaa
     9301 cgctcctcca gcttttacag aaaactcgtt cgttcctggt cctgtcaagt aagcttgcaa
     9361 taagcctttt tctgcataaa ttaaaggaaa ttcagcatct ggcgcaaatc cttgcgtaat
     9421 tccttcttct ttttcgttat atttttctaa acaacgccat aaattttctt catctgtacc
     9481 aaagataaaa cgaatacgtg tcttgaattc cacgccagca tcaatcaaag ctttgacggc
     9541 atacattgcc gcaatagaag gacctttgtc atcttgggat ccgcgaccaa ctaaccagcc
     9601 gtcttttata gttggatcga atggttttgt ttcccaatta ttttcgtccc ctgctggaac
     9661 aacgtccata tgacacaaga taccgaataa ttcatctcca gagccaatct ctgaataacc
     9721 gtaatagcct tctggatctt taaatgttct aaatcctagc ttttcactga tttccaatac
     9781 tttatccaaa gcttcaatca cttttttacc gaagggatgt ccttgtcctg aatctgcttc
     9841 atctagtacg gaaggaattc ggatcaattc gctcaatgat tctaatgctt gttcatgatg
     9901 ttgttctgtc acaaattttt tcatgatatt atcctcctaa tatgttaaaa agggtcatgt
     9961 caaattcctc cgacacaacc tcttcttctc aaataatgac gttttaagcc tgctccatca
    10021 gcaagcagag tgttcttaac aaatgatgaa agaaaaaaca ctcactgaat ggagctattg
    10081 acttatccac gtgcttatcg atagccgttt atcggtttct tcattcttat gatagacctt
    10141 gtacctgtat ttgtctaggt ttagaacatt gctgctacac ctaggatcac acagatggct
    10201 acaaataata tcgcaattaa tttaccggta aatttccacc acactgaaac atcgaaacga
    10261 gcaattgcta cagcacccat tacgatagca gatgttggtg taattaagtt tactaaacca
    10321 gatgcagatt gataagcagt gattactaaa tccttaccga cgccggcaaa ttcacccata
    10381 ggtcccatga ttcccattgt tgcagcagct aagccggaag ttgaaggaat caagaatgac
    10441 atagggatat agaaaataaa tgtaataatg atgaatacac ttgaagataa tgaacttaat
    10501 ccttgttcgc cccaatgtaa gatggtgtct gtgattaatc cattgttcat aaccacttgg
    10561 ataccacgag caacagctac tacgattgct acaccgatca aatcagaagc accagctaaa
    10621 aattcagaga caaattcaga ctctttcatg ccataagtga ttgctactac gatggacatt
    10681 actaagaata acatagtaat ttctgggaag taccagtcac ctaatggaag catgctttta
    10741 cctagaaccg tacctagtac cggaaggttt gttaaccagt ttgtcaataa ttcaaaaatc
    10801 gtgaaattcg cattcaaggt tgtccaagga atcaaactga tgatcatgat accaaaagta
    10861 ataaagaaca atacattaac atgtttttgt tttttcgtga ttacttcttg acgaccgatt
    10921 gcttcaatat cgaaatgctt catatcttct ttacgttggt tgtatactaa tgattttgtt
    10981 ggatcttttt cgatctttga tgcataacga tacacatata caatagaaat agctaacaaa
    11041 ataacgaaca tcaagaatcg aagaccaata ccttcaccca tcgaaatccc aacagcttgt
    11101 gaagctacgc ctgttgcaaa aggatttacc gttgaagcta gacagcctac ttgagaccct
    11161 actaatacga ttgctacagc tactactgta tcaaagccta cagccatcat gactgggatc
    11221 agtaaagcat agaatggaat cgtttcttct gccattccgt aagtagagcc gcctaatgca
    11281 aataacagca tcaatactgg aataagcatt ttttcttttc ctttgaattt cttcacaact
    11341 gaagcaatcc cggcatctag tgcccctgtt ttgttgataa tacctaaaaa tccaccaaca
    11401 accaaaatga agaaagagat tgggattgca gcaggtgttt ctttagttag ctcccccgct
    11461 ggtacaccta gcatcccatt gattggcgcc atgaaaatat cccacagccc ttgaggattt
    11521 tgttgtactc gttcatatga tccagcgacg atgttgcctg catcgtctac actatagtgc
    11581 ccagctggta taaaccaagt aagtacagcg attactgcaa taataataaa taagaccgta
    11641 tacgctgaag gcatttgaaa ttttttcttt tttgtttgtt ccatcttctt cttcctttct
    11701 tttccgttag agacaacaat tttggctcta atgttatttt atcaaaaaga gtatcagaac
    11761 aaaaataata acacgcattt tgtaaaactt ttgttcaaaa agttcgtttt tccctattcc
    11821 ctcctctttt ttcaggtttt taaagctttc ttctttttca ttgtagcgtt tccttttttt
    11881 tataaacaaa cattttcgtc ttttaaaagg agaagaattt cacatttgca aagaattgat
    11941 tgatttttat gcataaatca aaaaaatact caaaacaaac aaataaaacg tttacattat
    12001 tgcatgtctt gtattttttt ccaaaaaaaa agaccaagaa atttcttgat ctttttgata
    12061 tttatttgac tgctgtatga cgttgttcga actgatgttg ttttcgactt aaccatggaa
    12121 gaagttgcgc atgcagcact aaaaagacag cactcacgat gaatcctttg atcaagttga
    12181 aaggaacgat cccaatcagt acatagtttg ctaaagacat gcccagcatc tgtgttgcgt
    12241 tcagccctaa aaacattaag taaagaggcg taataacgaa ataatttgcg atactcataa
    12301 aaatagttag agcgatggtt cctgtaatga cacctaaaaa tttgtttctt cctttatgct
    12361 gtttctttac actaaagaaa taataaatcg ggaatgtaaa gatcgttgtt gataagaaac
    12421 tagcagtgtc tcctaccaaa ttatccggag aaaaacctgt agtcagcaga tgtaatactg
    12481 aacgcaagaa cgctgttgca actccggccg ctggaccgaa taagaacatg ctgatcaata
    12541 ccgagatatc actaaaatcg atcttcaaaa aactaaaagc cggcatgatc ggaaaagcaa
    12601 aatactgtaa aactaatgcg atcgcagcaa acatcgctac tgcaaccatt ttctgtacac
    12661 gggtgttctt catttgaaat cctcctgtta ggactcctct tcagcgaact ttttgacgtt
    12721 tctctccaaa tgaaaaaact ctattttcca gggaaaatag agttagagtt atttgatcaa
    12781 gcgtcgtcaa ataagctcta tcttctttat ccagactata ctgtcggtat cggaatttca
    12841 ccgattcagc tatttttttg caaaataggt cgtggactat aaccaccggt cgggaatttc
    12901 accctgcccc tgaagacgaa ccttatataa tttttgttta catattcatt atacatatct
    12961 attcaaaaaa cgcaacatct aacacttata aaaagtaagt gttcattttg agtggttcag
    13021 caaactgctg acttcttttt tgttcagttc acggtaatcc ccaggacgta ggccttgtaa
    13081 agtcagatct ccgtattttt cacgttttag tttttgcaca ggaagaccaa ctgcttgaag
    13141 catatttttc acttgatgat tacgtccttc gtggatcgtc aattccacga tactgtggtt
    13201 tgtcttagga tccactgata aaatttggaa tttagctgga gatgtttttc gtccttcgat
    13261 ctttattcct tttgtcaaag gtgcaagcat cgattttgta gcgatccctt ttacctttgc
    13321 aacgtaaact ttatccactt catgttttgg atgtgtcagg cgctgagcaa aatctccatc
    13381 atttgtcagt agcaagatcc ccgaagtatc gtaatccagt cgacctacag gatagatacg
    13441 ttcttttacc atcggcaaaa gatccgtaac aacttttctt cctttgtcat ctgcaacagc
    13501 agaaataact cctttaggtt tgtacaataa atagtaaccg tattcttctt gataaattgg
    13561 gacttcatcc acttccacag tgtcatgttt cccaactttt atccctaatt cccttacaac
    13621 ttgtccgttt acttttacac gtcctgcaag gatgaattct tctgcttttc gacgagaagt
    13681 gatgccagcg tgggcaatta ctttctgcaa tctctccatt acaattattc tcctttattc
    13741 attccatcaa agaatagatc tggtgacacg tcttcttcaa gtgaaatttc catttcttgt
    13801 gtatcaggca gttcttctaa tgatttcaaa ccaaaataat ctaagaagta gccagttgtt
    13861 ccatataata tcggccgacc tggtccttct actctacctt tttcttcaat cagtttatgg
    13921 gcagctagac gctgtaccgc tcctgaaacc tgaactcctc gaatctgctc gatttcagct
    13981 cttgtgattg gctgtttata agcgatgatt gctaaggttt cgacggcggc ttgagataat
    14041 gtgtttgatg tcccttgcgc atatcgctta agtaagggag ccagctcttt tttagtcgtt
    14101 aatacataat ggctttccgt ttcaaaaata tgcaaagctg agtgcgagtt ttgagtgtaa
    14161 gattctttta attctttcac taaacttgtg acttctgctt cgctgagatt taacagtccg
    14221 cttaattctt cattactgat cccttcctcg ccaacaataa aaagaagggc ttcaagttca
    14281 cttaatttcg tcatgttcgg tatctcctac tgctggataa agcataattg attcatagtt
    14341 ttctttttgt tgcgcaatga tctgcccttt tttcatcaat tctagcaaag ccataaaagt
    14401 agtgacaact tcacttttag aaggtgactc aaaaaaagaa tcgaaagtac agccatgcgc
    14461 atttcttttt atacgctctt cgataaatac cattcgttct tcgatcgttg tgtcatcggg
    14521 cgtgatcgtt ttttccactt tttgagaaaa tttcttacgt tctaagattt tctgcatggc
    14581 acggatcaaa tcgatttttt tgacttgtcc tcgcttcaac ggcttttcag catccgctaa
    14641 cccatcgatg ttcataggtt cttttgtgta ataaagactt cgttcctctg ctttttctgt
    14701 cagtctttca gctgcatatt tatatttacg gtattctaaa agctgagtga ccaattcttc
    14761 tcgaggatct tcttcccata attcttcatc gtctgtgacg aattcttgga caggaagcaa
    14821 tgtcttgctt ttgattgcca tcaatgtagc agccatcact aagtattctc ctgcaacagc
    14881 tagctcgagt gttttcattg tatggatata attcatatat tgctccgtga tcgtagcgat
    14941 cggtatatca tatatatcga tttccatttg ctgaatcaga tgaagcagca gatcgagagg
    15001 accctcgaat acatctaatt taatattgat ctccgtcaac tcattcactc tttcttcttt
    15061 ttctttgcta gccattttcc aatgtaaggc tctgtgattt cagttgcacg gatggagaca
    15121 tccgggtact tttcctgtaa ttcatctaac atttgaaagc ccatattctc accgcgataa
    15181 gacggattca aagaaatgtc atggatgatc agctgatcgt tcgttgccca gtaaatacca
    15241 ataatccctt gaatgttggt tgaaccttct ggcgtaaaga aaaaaagttc ataatcgtct
    15301 tcagattcgt acgtatcaat ctccttcaac aaagaagttt tacctgtcag tttcttatgg
    15361 aaactcaata gtcccatagc aattttacgg ttttctttcc ggtaatgtgt taacatcttc
    15421 tcaccttcct atgactaagc ccttggaaaa tgctgcttat aaacatccgt cattcttttc
    15481 ttcgtgatat gtgtataaat ctgagtcgta gagatatccg cgtgacctaa caattcctgt
    15541 actgtccgca aatcagctcc attttctagc agatgtgtgg caaagctatg ccgcagcgta
    15601 tgtggtgtta cttctttgta aatcccagcc tctcgtacta actgcttcag atttttccag
    15661 attccttgcc gagaaagacc tttcccatga ttattgacaa atacatgcat ttcagatgcg
    15721 tcctttacaa gtaatggacg tgcttcgtct aagtagcgtt ccagccattg gatcgcataa
    15781 tcacctaaag gaatgatccg ctctttatct ccttttccaa ctgtctgtac cagtccaaga
    15841 gaaagatgaa gatctcccaa tttcaatcca atcaattcac tgacgcgcat cccagtagca
    15901 tacatgactt ccaagattgc acgatctctt atccctaacg tttttgtcgt atcaggtgct
    15961 tcaatcagct tttctacttc tgtcagagtc aatgtacttg gtaatttctg tgctttcttc
    16021 ggcgtatcga tatgttgcat cggatcatga tcagtgatac gctcttgccg taaaaactga
    16081 tggaatcttc tgagacttga gatcatccga gtaacagttg ctgtcgcttt tttttcttca
    16141 tgcaacttct ccagaaaacg gatgactaaa aagcgatcga catcctgcca tgaagcaatt
    16201 ttctgctcct gtagaaaatg caagtactgt tccaaatcac gttcatagct ttgtcgtgta
    16261 ttggcggaca atccccgttc aatattcaag tagtggagat aatcgttgat ttgctctttc
    16321 ataataatcc ccctcatgcc tctctatcat atcagatacc gcttcattct gatagtcttt
    16381 ttccataatc tgagcaaaga aaaagccgtc tagacactca gacggactgg tttctttttt
    16441 ctttttcata gcattcctga cagattccat ggaacgttag ccgatgatct tttactaaaa
    16501 aatgataacg ttcttctact acttgctcca cttcaagtaa aagatcctct tctacttcct
    16561 cgatcgtgcc gcagttcaag catagtaaat gattatggaa atgtttggcg ccttcttttc
    16621 tcaaatcata acgggctaat ccatcattaa aacttacttt atcgacaatt ttcaattctg
    16681 tcaagatttc aagggttcga taaacagtag caagtccaat ttccggactc ttttttttca
    16741 ctaaaaagaa gatttcttct gcagataaat gctctttctc attttccaaa agcacaagca
    16801 gagtagcttc tctttgcggt gtcagcttaa accccgcttc atgtagctgc tgttttgttt
    16861 ttttcatcgc cgaaatagca ttcatgacca tttactcaac cccaacaatt tataataatt
    16921 acaaataaaa aaagatataa cactatgtta attaaaatta ttataagcta gttaagaaaa
    16981 acatgcaagg gattctcaat tagatttttt gactagtttt gtcacaccgt tttcttgtgt
    17041 aatcaatcct tgtttcaaaa gattacctaa tgcgcgctta aatgctcctt tgctgatacc
    17101 aaaagctttc atgatttctt ctggatccga tttatctgta aagttgattt gctgatctgc
    17161 agaacgttct aaaatggtta aaatcatttg tgcatcatct gatatagctt catatgctct
    17221 tggcttcaat gaaagattca gtacaccgtc tggtcggaca ccaatcactc gaccttttat
    17281 ctgctcgcct agacgaggtt cattatatcg ttcagaagga tggataaacc caagatagaa
    17341 atcttccgtt aaaacgtacg tacctgttaa tttcaagcgg tatgctgttc ctatcacatc
    17401 tttgtttttc atttcttctg ttccatattt gcttaaagat ttgaatattt tttcatctgc
    17461 taaactgccc caaatacggt cttttgcatc aactctaagg gaaatcatca agcgatcccc
    17521 ttttttaggc catagctctg tcattgtcgg caattcatca agagatacga caaagtcttt
    17581 atctggaaga ccgatatcga caaacgcacc taaatctttt cgtgtagcag taacgattcc
    17641 aaaagcgtaa tgaccgatac ggcttttagg aatttgtgta gtgatccgat tttcatgttt
    17701 ttgattttgg taaccgaatc cttcaactgc ttcaccgatt ttgtgttcac cttctgattt
    17761 gcttaagcca aaggtttgtc cgtttttttg gacaaagtag tttttttcat tttcatcaat
    17821 aataatacct gtaaatatag ttgctaataa atcgttcatt tttttctccc tctatagtga
    17881 aaggttttct taatacattt ctttgctatc ataacataat gttatctact tgaatagctg
    17941 agccttggtt tggaaaggtg aaaaaaggag tatgacaaca gttgtgtcat actccccttt
//
LOCUS       DAZKPE010000052        17936 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000052 DAZKPE010000000
VERSION     DAZKPE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.052"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(49..354)
                     /locus_tag="ACG930_002019"
     CDS             complement(49..354)
                     /locus_tag="ACG930_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFQ0519175.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(443..1474)
                     /locus_tag="ACG930_002020"
     CDS             complement(443..1474)
                     /locus_tag="ACG930_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0519176.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            1681..2556
                     /locus_tag="ACG930_002021"
     CDS             1681..2556
                     /locus_tag="ACG930_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0519177.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(2708..3550)
                     /locus_tag="ACG930_002022"
     CDS             complement(2708..3550)
                     /locus_tag="ACG930_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0519178.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(3642..5519)
                     /locus_tag="ACG930_002023"
     CDS             complement(3642..5519)
                     /locus_tag="ACG930_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0519179.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(5516..6937)
                     /locus_tag="ACG930_002024"
     CDS             complement(5516..6937)
                     /locus_tag="ACG930_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0519180.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(6940..10329)
                     /locus_tag="ACG930_002025"
     CDS             complement(6940..10329)
                     /locus_tag="ACG930_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0519181.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            10586..11977
                     /locus_tag="ACG930_002026"
     CDS             10586..11977
                     /locus_tag="ACG930_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519182.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYKLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(12050..12697)
                     /locus_tag="ACG930_002027"
     CDS             complement(12050..12697)
                     /locus_tag="ACG930_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0519183.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(12705..13391)
                     /locus_tag="ACG930_002028"
     CDS             complement(12705..13391)
                     /locus_tag="ACG930_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519184.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(13397..14470)
                     /locus_tag="ACG930_002029"
     CDS             complement(13397..14470)
                     /locus_tag="ACG930_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519185.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            14692..15366
                     /locus_tag="ACG930_002030"
     CDS             14692..15366
                     /locus_tag="ACG930_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0519186.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            15371..16711
                     /locus_tag="ACG930_002031"
     CDS             15371..16711
                     /locus_tag="ACG930_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFQ0519187.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(16860..17846)
                     /locus_tag="ACG930_002032"
     CDS             complement(16860..17846)
                     /locus_tag="ACG930_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFQ0519188.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         5086 a         3376 c         3258 g         6216 t
ORIGIN      
        1 aagcaggtga ccaaatgtct cctgctttta tgaattgatt tcgtccgatc aatgatgatc
       61 atgtttattt tttgaggtca gttcttcaaa tttttctttg acatcttcaa ccgctttttc
      121 gatatctttt tcaaagtgat tgggctcatt aggctttgtt tcctcttcta cagaatttga
      181 accagataaa gctgtttctt tattttctgt ttcaccagag tttgtgccag ctaatgattc
      241 ttctttgtct tctgtttcac cagaattagt tcctgctaaa gccacttctt cttctgtttt
      301 aggggccatt gaacctctta atcgtttgtg tttttcaccg tcataatttg tcatgttggt
      361 tcctcctagt agttctatac tttttcatcg tacaataaga cagtttatgc gtcaaaaaac
      421 aaacccgatt cttacaaata tgtcatattt ttccttctga ttcttgaatg cttttgattc
      481 cttcttccaa aattttcatt tgtaagattg tttcttcatc tttgatgact ttttctgcgc
      541 cattaactaa tgtctcgtaa atcccttcgt agacacggct gtaatcacca acctcggaaa
      601 ttactttttc ttcatgataa ctcccttgtt catctatata ggtcaataca ccataatgtt
      661 cgggcaaatc gataccaaag tcttcatgat caggcatgta aaacattttc agatgttctt
      721 cttgtcgatc ttttgtttgt ttcacgaaca tccctttttt tccgtaaacg acgaaacttg
      781 gacgttcttt gatgcggaaa taactggatt ttatcgaaat tttcatattt ccatagaaaa
      841 aatccagatc gaagtaatca ttcattcgtc ctttccctaa aagttgacgt acatcatagc
      901 tgatatcatc tggttcgccg aaataagaaa gaacttgatc tactgtatga caagcatgtc
      961 catataaata gctgttcgca gtagaaaatt catgcgtatt ttctggtact tccggtctga
     1021 aataatcata atgcatttct acttctaaaa tatcccctaa ttttccgctt tcgattactt
     1081 tttggactgt caagaagtca gaatcgaacc gtctgttttg gtaacattgg ataaatagac
     1141 ctttttcttt tgctaatgca aataactctt ctgcttcctt tgacgtttct gcaaaaggtt
     1201 tctctactag tacattctta ccatgttcga gtgccatttt tccatattca taatgaaatt
     1261 gactaggtgt agtgatgaca actaattgga tctcaggatc atcccaaaga tcagacagct
     1321 gatcagtata ttcgatgtct tcgaatgttt tccacactgg ttcagatggg gaaaaaattt
     1381 ttttgatatt gattttgttc gtaagttttc ttgaaaaagg caaatgatag cgatttgtac
     1441 tctttccatt gccaagataa gcgattgtaa gcatgagtgg tgcctccttt tattgatgtt
     1501 ttcagtatat cctagaaaag cgcagaaagt atttataata gctattctgg taaaaaagtt
     1561 cagaaaaaca cttgttatca ttcggtttgg tgaaattaat gttcaaagta aggataaaaa
     1621 tcaaaaagat agtagcggaa ccaagtgttt atcagtaaga tagaatttgg aggtcagatc
     1681 atgcttattg aagaaaaact aacaaaacaa gagttgttta ccacgacaga gaaacggatt
     1741 gtcgattaca tccgtaggaa tatcgaagct gcagtctaca tgacgattga agaattagca
     1801 aaagctacgt atacttccca ttcagctatc attcgtttat gcaaaaaaat gggattcagc
     1861 ggatttaaag aattccgttt cgagctgggg cgggaagttc atcaattgat tgctcagttc
     1921 aatcaaacga ttgatcctaa ttttcctttt tcaagtgaag atagcactca gcaaattgca
     1981 aagaaaatgg cggatttatc gatccagtca ataaaaaaag cacaattgca gattgaacat
     2041 gaagatttag atcaaatcgg taaagtattg aacaaggcac agcgaatctt tctttttgca
     2101 aaaggtgatt ctcaaatcac ggcaaggaaa ttccagaata aaatggtcaa gttgaataag
     2161 tttttgatca tggctgaaga atacagtgat tcttcttgga atgcagccaa tttgactagc
     2221 gaggattgcg ccatttttat tagctacagc ggtcgcatcc atcattatga acgaataatg
     2281 acctatttga agcatgtaga ggcccctacc ttgctgatta ccggaaatca gcattcagaa
     2341 atggccaaac aggctgatat gtgtcttgtt atatcgcagg aggaatatga ttttgctaaa
     2401 gtagcgactt tctcctctca aattgccttc gattacgtat taaatacgtt attctcagtg
     2461 atatattctc aaaattttga agagaatatc cgcaacttga aaaacaaaca agaattgatg
     2521 caaaaaggcc ttcttaaaga atatcggaaa acttaagaaa agatcctcat ttagtaataa
     2581 gaaagatagt gtttgatagg ctctctttga tatcatcata aaaacaggct gaagttttct
     2641 ttttcaaacc tcagcctgtt tgtttacgga acgattcgaa tagatatatt atagaaatga
     2701 ggaatagcta acttctgttt cttattttga acgattgacg aaaaagatat ataagaagga
     2761 ggaaaatcag tatacatgca gctaacaatc catacaggaa aaatcgtttg ttctcggata
     2821 ctttctgtac ttctttttga acttcttttg catgataagg aacccggtgc cctctgacaa
     2881 gtaagcgatg actgttgacc atataaggtg tacaagttag gagtgtcacg aaatcctgcc
     2941 ctttttcgat tctcagatct tttgtatcag tcggttctac cgtcttgatc tgatcgactt
     3001 gataagcgag tgtccgtcca ttgatttcga tatagaaaga atcacctaaa gtcagtttcg
     3061 gtaagtctgt gaacaacttt gcttgaggca gtcctcgatg gctggaaata acggcatgtg
     3121 tattttctcc ccccgtagga taagacgttc cttccaataa tgaggcacct ttttctagca
     3181 gcacagtatt cgtttcatca aaaattggca aatggacatt gatctcaggg atcgtcaaaa
     3241 taccgatcgt atgtttctca aaataggttc tatccttttt cgcaggttct tttttcttag
     3301 taaagggatc tgcacctgga tttccacctt cttttgctaa ttgctggttt ttctttgtca
     3361 tgttttcttg gattttagcc atgacttctt cattttcttt gaccgcttgt tgctgataat
     3421 gagagatgat ctgctgatcc agataattat tcagcgcgtc gctaacaaat ggataagcta
     3481 gtatccctat tcctgagaga agcaagaaaa gcatcagcag atctagaagt ttccttttct
     3541 ttggtttcat ttgtgttctc cttgtgatga ctgtttgata ataaaagaaa aaggagcatt
     3601 tgcgtaatcc gctgctcctt tttccaattc ttgcaaaaag actaaatctg actgtgcttg
     3661 cgtctagcaa agtacagtcc agcaatcagt agaaggacta ctcctgcacc gatatacaca
     3721 tagattccct taccgcctgt tgaaggaagt gtacctttgt gtttatttgg tattttttca
     3781 ggagaaatca actgtcctgc tgttacataa gattgttcat cgatagtaaa tgctacacgg
     3841 tttgttaatg gaacatattt ttctggcgct ttcgtttctt ccagatagta cgtgccatat
     3901 tttagacctg tcacatcgat taaaccgtta cttgtggttg taaaaaccgt tgctgattct
     3961 ttcgccgata cccagctgac ggcttttgtg gatgggtcga tcgataaata tttcgctgtg
     4021 tcactatctt gatcacgaac gacgaattct gctccagcaa gtgtttggtc tgatgtaacg
     4081 tcaccatcta ctttaacaaa tcgtttgccc ccagtaacga catcgactga cggtggtgtt
     4141 tgatcatttg tatgcccgtt atcgacattt gcttggttag aaaatccttt ggttggatct
     4201 gctttttcgt tcaaatgcat atagtaaacg aatttcaatg taccgccagg agttaatgaa
     4261 ggaatataat tcggatcaac tgaaaccgtg aatccgtctg tttgctcagt gacagaataa
     4321 tttactgggt cgatttcttt atttccatca tataaggcat aagcatacgt tcctgaagaa
     4381 tcattatcaa atgttaaagc agcgtcatga gtatcgataa gtttgaatgt tgtgtacttg
     4441 ttttgcgttc cttctttatc agcgatacct aatgggatat tgacagaaat ctcatattga
     4501 attttttcac cgattgcgac atcttttcca ttcaattgag gtgttgtttt atcaacttta
     4561 gacgtatcat ttttgatggt cttttctact ggtgtttggc tatttgccag gatctcaaaa
     4621 ggcgtgattg tttgcttttc aatcatttcc gcattatcag gagcttttac ttcttctaaa
     4681 ttatattttc caacttctaa atgattaacg atcaactggc ctttttcaat agatgcctcg
     4741 gcaaagtcat tgttgccgat gtcataagaa tgaccagtaa tgaaatgttt ggctttggtt
     4801 tgatcagttg tccaagtgta caatccatct gtgacacttt ggatgtattt tttgacgctt
     4861 ggtgttcctt cttctttaga aataataaat tctgctccat ttagtgcttc gttttcggca
     4921 gtaccgattt ttgtaacttt caacgttcca tcattaccga ctgtattttt agggtagaga
     4981 tggatagtat ctagttcttc tgtcccgtat ttataagagc catctgcttg tttgatcatc
     5041 tcatatacag ggaaagctaa aaccatgttt gcggcagctg acactccgtc ttttggttct
     5101 tctttgatcg tgtagactgc atctttccca ttttgttttt taggtaaaga taaagtgaca
     5161 tttccatcag catctgtcgt tcctgaagca actggtgtac caggagtcaa agactggact
     5221 gcttgttttg ctgcatccac ggacgctcct ttatctcgtt gcgcataaaa ttcttgagtg
     5281 acgttataaa ctgaaaatga aatatcggct aatccttggt attgatcgaa ttcgctcatt
     5341 tctttcccgc tgttttggat taaaggatcg ggtaaatcag tcattttctt tttatgaagg
     5401 atgacttgag ctgctgtctc ctctgcaaac actttttttg cgccgaagct gtttgtgagt
     5461 aatggtaaaa taaggaaaag gactcctaac ataacgttta tttttttatg atttttcatt
     5521 ttttcactcc tgttcttttt ttgataaaca accagattgc aaagcttgcg aataccatac
     5581 caacaacgcc taaaagtgta tttttcgttt cgtttgtttt tggaagaaat ggacggctat
     5641 tttctttttt attgactact ttcaatatac tgtccgcctc tttatcctca gaaagaaaag
     5701 ttgaaatggt aaacggaatt tctgtttcac ttaaaatata accagaaggt gcttcgatct
     5761 cttttaatcg ataacttcct gttttcaacc cggaaattga aaaagcgcca tttttatcgg
     5821 aaatcaggtg aagcgcatct gattcgttct ttgtccactt gtatccgttg gctgtttgct
     5881 ggaggtaatt tcctgctttg tttttaataa ggaatactgc gccagctaat cgtttatctg
     5941 gtttatttgt ctcgattttg acaaattgct tactccctgt atatacagag actttctttg
     6001 tactgacacc aaaaccaaaa tccagtgttc cgttgttgtt gatttccttg ttcgcctgtg
     6061 ctgtactgct tagctgcatc tgataagaaa tggtcagttt ttttccagca tatttttcca
     6121 acgaagggat cgaaaataaa acatcaaatc cgtgaggttt cttgtgtatg acaaagcctt
     6181 ctgtcagctt ttctccattc gatgaaatcg ttaaactatt aggtaaaaac gttaatgctt
     6241 catccgcact atctgacaat tcgaactttt gatagtcaag gatatttaca ggaattgtcg
     6301 tatgcaagga ataagtgatt ttttcaccaa tcgtaaaatc atttctaggc tcttctaata
     6361 ccttctcaaa aggtggatca gggtagtcgt tttcttcatt tttaggatac aaatggatag
     6421 ttgaaagttt ttgattgttt tgtccatgta caggaagaac aactaccata ttctctgcct
     6481 tttctttgac gacttctggt actttggatt caatgaaaag atacgcttta tctctttttt
     6541 cttgatcttt agcggccaga gaaaaagaag cgataccatc ttcgttgtta agagttgtag
     6601 ttgttgcttc tgcggtaaac ataccggaag acgcaccgtt ttttgcgatc tctgcttgtg
     6661 cttcttctac cgttttgccc ttttcccgta gatggtaaaa agaatctgtg acatcataaa
     6721 cttggaatgt gacaccattt aatcctcgat acgtttgtaa taaagctttt tcttgtccgt
     6781 catttggatg atttttcggc agttgcccgt ttgggaaaag caatttgtgt aaagtaatct
     6841 gaaccatttc tgtttctgtt tctgttgcta cctgagtaaa agctggttta aatagtaaca
     6901 agaagagaca catactaagc caaccaagtt ttttcatatt tagctgcccc ctctttcttt
     6961 tttcaaaaaa agataccaaa tagaaaacgc acaaccaatc atccctacta gatagattcc
     7021 taaacggcca attcctcccg tttcaggtaa tggtactttt gcctgattcg tgatgtctaa
     7081 agaaatctgg ttgtttttgg ctcctggtga cagaacagat tcatgatctt gtccatccac
     7141 ttgaattgac ccatcttcgt gtataactat agtaactggc tcttttagac cttggtatcc
     7201 ttctggtgta aaagtttcgg tcagcgtata agttccaggt tttaaatttt cgaatagaaa
     7261 ggtatctgtt tcttgtccat cttttggcga ttctaagtcc atttctggtc cctgcagtct
     7321 gaattttgct ccttttaatg tctgtccgtt gtcttctttt ttgtgtaccg ttagatcaaa
     7381 cgcttttagt cgattttgat gagtgagcgt ccatacatta tttgtcatct cggtattttt
     7441 tcccgtgtaa atgatttttc catatttatc gatttggaat tcataatttc ccggcgaagt
     7501 atcatatccg gcaggaccag ctgtttcaac gactcgatat ttaccaggtg tgagtgaatc
     7561 aaaactggca agaccttttt cattcgttgt ttggctgtca attggctgat aagtaccatt
     7621 tgcttctttt ttctgtaggg aaaatgctgc tcctttaaga tttatctctt tgtccgtccc
     7681 ttgcatcgca tacttacgta ctgctacagg aacttcaaca aaaggatttt caatagtcaa
     7741 ctggatcgta tcatcggaag tagtgactgt ttttccatca atggttaccg taccatcaga
     7801 agcgatcttg atttcccaag tagtcttttt gcttaatcca tgcccttctg gagcttttgt
     7861 ttctgtcagc gtataggtca tttctttttg caatttgaca ttttctggaa gagaataggt
     7921 tccgtcgcca tgatctgtta gtaaagtatc aatagaatct cctgttaatt tgaaaacagc
     7981 gccaataaga tccttttcac ctgtagagga atttttcgtt attttcaagt ttaacggtgt
     8041 gaattgttta gtatttttcc atgtcattgc atctatttgt tgagaatcgt atcctggtac
     8101 aggtaattct ttgattgttt ggtaactgaa tgcttgacct tgattattgt attgaggtag
     8161 tgataatatc tcttgataac tttctccgct atttgcagat aatttgtcaa tgtctgcacg
     8221 ttcccacgta tttgttgtat ctttagctgg tttaatgatt cgaatatatc cgtttttcca
     8281 agctgcagca tttgtcgtat gttcccgttg aatctcaaaa gtaacttgat ctggacgatc
     8341 agctagattg ttgtcaaatt cttcccataa ctttttgatg tgaagactga ctccgggagc
     8401 tttagcagat ggtataccga attcagctaa ttcattggta tcaatgtttg gctggaaagt
     8461 tgtcctgccg ttcatttgat accagaaatt tggatggaag tcctcatttt ctgtttggat
     8521 tctcacttgg taatggattt ggatttcttg gtcttttcct aaatagatct gattgctctt
     8581 gatggtattt ccttctatgg aaatagatgg agtgaccgtt gtaggacttg tccccacact
     8641 cttgactgaa agtgtaccag gctgataaat gaatggttct gcgattggat catttatttg
     8701 tccattgctt acagttgctg agatctgtac agcttttttg gctaggtatt cagagatatc
     8761 tgttgcatga tcagctgatt catagtaaag atcgcctttt tcatctgatg aaaccatttg
     8821 tcgcatacga gactctactt ctgcttttga gagaccagct gccggatcgc tttgaagttg
     8881 gatgccaaga ccatgtattt cgattcctcg ttctttgagt gccatcgctt ctccgatggt
     8941 tgcgataaac gtactgtcga ttcttctgga tagattgttt tggtcaggtg catcatagat
     9001 tcttgagatt agagaagtat ttcccggccg atcttgcgta ttagaaaact gagttccgta
     9061 ataattgctg cttgattgtg cgtgtacccg ctgtacttta taggaaaatg ttggtacacc
     9121 atccgtcagc aaaacgatca cttttttatg tccatttgga acggatagca tgcttcctgc
     9181 atctcttagt gctttttgtg taaaagtacc accatttgtc cgtgaaggtg taatggattt
     9241 tacttgattt ttcactgaat caaatgaacc catctgtact gcaccgttac tgtagctata
     9301 tccttcgctt gagtagccga catatcccat attgattttg tctgtgatac cgctatctgc
     9361 taaagtatcg acaaaacgat cgacaccaat ctttacttca ccgatccgat tattgtcgtt
     9421 catacttcct gaccagtcta cgaccaatac gagatcaaga ggcgtgatat ctttttgtac
     9481 atttccacga gcattcaaat aaacatcaaa caatccgggt gtacttgttt cctttgcata
     9541 ctttcgtatc gcatagtctg cttgattacc ggttcctcca tattcgatat acgaatgggt
     9601 ccgatcatta ggatctccat tccaagaatt tataccatcc cattgatttg ttccgttttt
     9661 attgccttga tgatcaagaa catttgtatt tcctgtaggt tgccaactgg ctttaggata
     9721 agtgccctga tcatctgttg tatattctgt aggaatcgtt tgattagatg gcacactcac
     9781 agctggcaag gataatgtag gcaatgtaaa tgggctgaca gaattttcgt tttcttttga
     9841 tgattcttct tctatttcgt ctggctttgg tactgacaca tctgtatctt tcttattttc
     9901 tgtctcatca ataatgtcat attctttatt atcgacgatc agcttgtttg cctggctgtg
     9961 gtaaagtgct ggatcgattg gaaaactcag atcgatagtt tgtttagtgt ttgatgagat
    10021 ttccaacgta attttcccgc tatttacctg ataagcatag ccatctcctt cttttctttc
    10081 cacatcactt aagtaatttt cgactagacc aatttctttt tctatctttt cagcactggt
    10141 gttattcgca tttagcttga tgttcagtgc tttttttcca gactgatccg aaatgacttc
    10201 agctgaaatt gtttctaaaa ctgttggatc atctgtagtg tctgctattg cagataatgg
    10261 cacaaagttt gataaactca atattatcag catgaaaata actttcagtt tcttccctgt
    10321 ggtcgtcatt tttcccctcc tttttctttt tttctgtttt gacgtgaata gtgaaaatta
    10381 ttaaaataaa caggcgttac ataattttat ttattttaat atgataatta ttatacgaag
    10441 ggcgctaaag ggaatcacac caattttcat accaattggt ttcatttatg aagttgattc
    10501 cttcgattaa tgagcgtttc attgaaagaa aagggttgag ggagaaaaac atatgatcag
    10561 gttgttggaa ggaaactata gaaagatgga aaaaatcatt cgaattctgt ccatttctga
    10621 caagtggatg actaaaaaag aacttgccaa acgaattggt agttcagaat ctacatttgt
    10681 aaggtatatc gaagagatca aaatccgctg gggaacggat gtaacgattc aatcttcaca
    10741 aaaattgggg tatcgtcttg aacatttgaa tgtaccagct tatttaaatg ttctgatgga
    10801 aatgtcgcaa agttctacaa acagtcgttt attaaatgag attattgtca atccgggtaa
    10861 aacgattgag tattattgtg aaaaaatttc catcagccgg tcttctttta cacgtaagtt
    10921 gaaacaatgc aatcaaattt tagaaagcta tttattaaaa gtgatcgttg accaaggttt
    10981 tcagttaact agccttaaaa gtgagctcca gttgcgtatc tttgttacct ttttcttttt
    11041 aagttactac ggaagacgca cgttgccatt tccaatcgaa aaaaagaaga tcaaagaaat
    11101 tatggtcaag aataattgtc agatgaattt gtttcaggaa gaaagcccat atgagcaatc
    11161 tttctttatt atgtattttg ttgtgcatct catgagagaa tcccaaggaa ctccatttga
    11221 atggaaagct ggagactctt atgtacagtt gataaatatc gataaaaaag acttcttaat
    11281 cttgaaaaat ctcttaggaa aattgaagta cagcagctat ataaaagtag tgaactattt
    11341 tgtcaatacg attttttcag aattttcgga gaaagaaaaa aatgaaatca gtgagcagat
    11401 acgaaaaaat atgtcctact gttcgttttc atccgctgat tgcaaagaaa aaaacgaaga
    11461 atatgttgtt caattattaa cgcaaattta ttttttctcc cgtattttcc catacgatac
    11521 gactcatttg acgatccgtg caacttactt tgcacagcag atgcaacacc gccagatacg
    11581 tctatatgct ggatttcgtg cagaacttca attttattcc actctactga atcagaatct
    11641 gatttattat ttatctagct atatcttttg gatgcttatc ggtaatcctg aaattcacca
    11701 ttatacttct gataaaaaaa tactgattat cagcgactta agtcttcgac atagtcaata
    11761 tattgaagaa tatatcagtg atattcttgc tgtgcataaa attcactctg agacaactgc
    11821 tattactgaa gatcagctgt cgaaatacaa acttctcgag tatgatctga tcgttacgaa
    11881 tcaacccatt ttgaatgccc atgttcctca tatattgatt gatgatagtg tgtcattcgc
    11941 aaatgaagaa gaactcatcc gcttattcga gttatgaata atcaaaaaac agctatgtat
    12001 aaaccaccct gataaaaatt tcaggacaaa tacacatagc tgtttctttt tattgtattc
    12061 cttcagcaat ccaacgagat ttatagcgaa agtcttttaa caactcttct tttgtccaat
    12121 tatttgcaat gagatccgtc aaagtgttca ttacgagggt catggaaaag tataggaaac
    12181 taactgcttc ttccgacgat tgaatggaga aatgattgat tcttaataat tccagccatt
    12241 tttcgttcat tggagaatca gccgatagtt ctctacgttt ggttgtctgc tgatcatttc
    12301 gctgggttaa caagtataac ctttgccaat agatactttc gtgatctaag tcgcagcacc
    12361 actctaaata tttttcgatc cccaaaaaga aatgttgttt gttttcgcta atgaatttta
    12421 agatatcttg atggactatg tgagaactgc ttttgatcgt atacaaataa gcatcttcca
    12481 aatcttgaaa atatttataa aaagcaccgc gcgacatccc catcttgtca acgatttctg
    12541 agactttgac ttggctgatg tgctgtgagc aaaatatctc cagtaatagg tcatcgattc
    12601 tctgtttctt tgcgttcgat aaattgaaaa aagtttcttt tggcatccac atctctcctt
    12661 tatctctgat tatacgtgga tagcccttca ttgtcatgaa ggattcattc cttctttttc
    12721 tcttcttctg tcaagtaccc atcttccatt cgataaacgc gatcactcca ttgaatcata
    12781 cggacatcat gagtaaccat aatagtcgct ttttgtttct catgagcttc tttaactagt
    12841 aatttgacga cttcatatgc atgatctgta tccaaactag ctgttggttc gtctgctaag
    12901 atcaagcttg gctcattata taaagcgcga gcaattgcca ctctctgtct ttctccacca
    12961 gaaaggtctt taggataact atttttaagt gactggatat ctaaagattg cagcaaggaa
    13021 tcgatttttg ttgaatcttc tttttttgaa gtaacttggt caactagttc aaattgttcc
    13081 tttaccgtta aaaaaggaat caaattagag ctttggagaa taaatcctat ttctttaaag
    13141 cgtaaatctg ctcgtttttt ttctggaagc tcagttagtg agtgaccgtt gatcactatt
    13201 tctccggaag tcggtgtttg caatcctcct gaaatggtaa ggaaagtact tttacctgaa
    13261 ccagaaggac caatgatgct gacgaattct ccttccttta cataaaaatc aattgctttc
    13321 aaagctgaga cctttgtatg accagaacca aatgttttgg taactttttt catcgttaat
    13381 atttttttca tttttattaa cctcctattg ctgtaattgg gtctactttg gttatcgtac
    13441 gtatcgaaaa caatccgcct agcattgcga caatgatcaa aatcccacta tatagcaacc
    13501 attgtgacca aaaaacagca aaaggcatcg cgcttggtaa aatcagacta gtcaaataag
    13561 caaacaaaag agcaagcaga acgcctacca ccccaacaat aaaggactgt gctactaaag
    13621 atttagcgat gaagaaattt ttgatccctt gtgctttcat tactccaaaa atagcagtct
    13681 tctgaagtgt catcacgtac atgaaaatac cgaccacggc agcaaccact aagaacaaaa
    13741 agtatatcat cgcatttaag gtcatatttt gggcagaata gccaggaata ctttcaatga
    13801 atgtcccaat agttaataac tgtagaccct tcgatgcttt ttctttcgaa attttagctg
    13861 aatcctttat tacgatccca ttgatcggct gttcttcttc agaagcaaac ggctgttgtc
    13921 catacttcaa agcagtccac gtatctaggg acgcatagat gacgggagaa actgtgtaat
    13981 aagtttcagg aaagataccg acaatcgtca aaggatcgtc gtaactgcca attttgatcg
    14041 tatctccaat tttatagcct gaatcagcca gattttgaga gatgatgatt tcattctttg
    14101 ttttaaattc atgccctttc gtgagttttg gtaataaaaa tgcttctttc gttgtgccga
    14161 aaactgtaac attttctttg ttttttcctt tgattgctcc gctgtacaat ccgattggtg
    14221 ctttctctcc tccttcaatg tatttcagat ctcctcttgt taattgtgaa gctgcaaata
    14281 cttgatttgc atcctccgac aaaacaatct cttgtgcgtc ccaatcatcg attgcttttt
    14341 taaactcttc tgaaagtcca ttcgctagtc ctgacaacat gaatacgaca tacgcaatca
    14401 agaacataat accgacgatc aagccatatc gtaatttaga atagcgaatt tctttgatag
    14461 ctagaaacat ttgtttttcc tccctatgat agattgatag tgacaaaatg tcacttgttg
    14521 aatagtgtaa ctctaaagtg acaatttgtc acttgtgttg tttttttctt atcaataaat
    14581 tgtctaagac atctttcgat aaaaccttaa catgagtcat aaaaaattta tttaagcctt
    14641 atttatgctt tccatgataa actaaagtga ccaaatcaat gaggtgggaa aatgattaaa
    14701 ctattagtag tagaagacga taaagtatta tccaataata taaaagaaat actcgctgca
    14761 atcggcgaga taacacaagt ttatgatggt agtgaaggac tgttcgagtt ggaaagtgga
    14821 gtttatgatc ttgcaatctt ggatttgatg atgccggaaa tgaatggata tgaagtgtta
    14881 gcaaaaatac ggaaagaaaa aatacagact ccagtattga ttttgactgc aaaagatagt
    14941 ttggaagata agattgaagg atttgaacga ggtgcagatg attatctaac aaaacctttc
    15001 tatcgagaag aactgatcat gcgcgtgaaa gcattattga aacgctcgct aggtctcttt
    15061 gatgaaaatg ttctgaagta taaggatatc agttgtgatt taaaaagcaa tgaagtcttg
    15121 tataaagaac aagttttgcc catacaagga aaagagtttg aattgctcgt ttatttttta
    15181 caaaataagg gaatcatttt gacaaaagag cagatatttg accggatctg gggatttgat
    15241 tctgatacga cgattacagt tattgaagtt tatatgagca acttacgaaa acatctgcga
    15301 agtactggat tggataaaga aatcaaaacc ttacgtaatg tcggttatat actgcaaagg
    15361 gtgtgatgca atgaatggag atattacacg aaagcaacgt agtcgctttt ttgcgacaaa
    15421 tgtagcagca tttgctttta tcttttttct tttgggattc attactttac agatattaaa
    15481 ccaatctgca tacagagaaa cagatctgtc attagagaaa ataaattttg attctcgaac
    15541 agtacaatta gagatacaaa gatatcagca aggcgatccc tttttaaacc cgactcaaac
    15601 ggaacaaaac agaacaaaca tggaacagcc attaatggaa ccatcaaatg accgttttaa
    15661 cactcaagtg atcttgtggt ctaaaaatgg tgagatattg aataaagcag ctattggtgg
    15721 gcgtttcaac caaatcaaag aattaaaaat ggatacgaaa aatctgaata ccatccaaaa
    15781 tattgaatta aatgaagaca gtggctcatc tgccctctct ttccgttcga ttacgaaaaa
    15841 agcggagacg aatcaagatg gcgttgccta catccaaatt ttagaaaata caaatcaaat
    15901 caagaattca ttagcgactt ttcgcacgat tatgattttg tgtatgattg ttttttggat
    15961 tctctctatt ggtatcagtt attacttgtc tagtctaagc atgcgcccta ttattctttc
    16021 ttggagaaga caaaaagaat ttgttgagaa tgcttctcat gaattgcgca caccgttaac
    16081 gattattcaa aatagtttgg aacatctttt taccaagcct aatcatacta ttattgaaga
    16141 atccgaaagc atcgctcaag cattgtcaga gacgaggcgc ctcactggat tgacttcgga
    16201 tttgctgaca atcgctcgga atgattctga tcagcagctg ctttcaaagc aaatgatcaa
    16261 tacacaagaa tatatcgaac aacttgttaa accatttcaa gagatggcca tcatagatgg
    16321 aaaagagttt attctccata acgatgcaac attagaagta ccaattgatg aaaaaaaaat
    16381 ccatcaagtt ttggttattt tgctggataa tgcattaaaa tatacgaatc cagaagataa
    16441 gatcattttg gattcatctg ttaaccataa agaatggctg attcacgtaa agaatactgg
    16501 cccttctatc agtgaagaag atcaagcaag gatttttgat cgattttatc gggaagatca
    16561 atctcgggcg aaagagactg gcggatacgg gcttggcttg gcaattgcaa aacaggtaat
    16621 cgaacagcat catggacaga tttctgtatc caattatctt ccacaaggag tcgattttaa
    16681 agtccaattg ccgttgaagc ctaaaaaata atgcttatcc ctaaaaaagg gctgtgacaa
    16741 aaatcttgtc acagcccttt tttgttgcga ataaacggtg ttccagaagt agcttcttcg
    16801 gaaataagcc gaaatttctt taagctgacc acttctgtca caacctcttt agcttacgct
    16861 tacgattttt tattgcggtc ttcaatgtgt acatcaccgc ttgtgtcaat atccaattct
    16921 tctcggctaa catcttctgt cactttttca acatcttcat gttcttcttt atgaatccca
    16981 acttcttcac gaataactgt atgtttgctt acatctactt gctcttcttt gattgggata
    17041 gtaatcgtgt catcttccaa tttttcgtct gttccctgtg aagattgatc tgttactggt
    17101 ttgcgttcga tgacgatttc ttcacgtttg accggtactt ctaccgtttc agtatcgttg
    17161 accacatgtt tgtggatgtc gacttctcca gttgtcacat catgtgtatt tacatctaat
    17221 ttttcttctt ttagttgaat tgtatcatca tctagatttg gtttgcgatc gatgtcttca
    17281 gtcttgcttg tacccattgt atcagtctcg ccaggtacgt ccatcggatc agttcctggt
    17341 gtcatattca atggatccgt tgtattttga aagcctgtcg tgccacctac gtccattgga
    17401 tctgttccag tgccagtttc taatccagtc cccattgtgc ttgctgggct aacagtatct
    17461 tgtgtatcca ttgtatcttc tgttgtttct ggctgacgat agccttttac tgtgatgaca
    17521 aattttccat cagaaatatc tcctctatat tgatataaag gatcattttc tggtgtagcc
    17581 gtctcagaat cataggtatc aaaagaaaaa gtatctttta ttttttccca taaagaacgg
    17641 tcttcttcac catccatccg attttcatct gtttcaacat ctataccaga caatccgtca
    17701 aatcctagtc tagatgctgc ttcatcagta gtataaataa cgatatcatc tcgttcatac
    17761 ccttcgttac gcaaccgttc aattactgat aatgcttctt ccctcgtact atagcttccg
    17821 atgaccgtta aatttttctc ttccatgtaa attcctccta gcaaatagat ttatgattgg
    17881 tatattgtta cttataaatt tattctatag gagacgattg ttttctacaa atattt
//
LOCUS       DAZKPE010000053        17812 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000053 DAZKPE010000000
VERSION     DAZKPE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.053"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            289..1146
                     /locus_tag="ACG930_002033"
     CDS             289..1146
                     /locus_tag="ACG930_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFQ0519189.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1261..2181
                     /gene="pstC"
                     /locus_tag="ACG930_002034"
     CDS             1261..2181
                     /gene="pstC"
                     /locus_tag="ACG930_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFQ0519190.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2181..3065
                     /gene="pstA"
                     /locus_tag="ACG930_002035"
     CDS             2181..3065
                     /gene="pstA"
                     /locus_tag="ACG930_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFQ0519191.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            3080..3886
                     /gene="pstB"
                     /locus_tag="ACG930_002036"
     CDS             3080..3886
                     /gene="pstB"
                     /locus_tag="ACG930_002036"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFQ0519192.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3902..4660
                     /gene="pstB"
                     /locus_tag="ACG930_002037"
     CDS             3902..4660
                     /gene="pstB"
                     /locus_tag="ACG930_002037"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFQ0519193.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4673..5350
                     /gene="phoU"
                     /locus_tag="ACG930_002038"
     CDS             4673..5350
                     /gene="phoU"
                     /locus_tag="ACG930_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFQ0519194.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5496..6617
                     /locus_tag="ACG930_002039"
     CDS             5496..6617
                     /locus_tag="ACG930_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFQ0519195.1"
                     /translation="MQAFEHCLFGKGFVTKYVTNPFHHFIERIKNAKKISIITIFFIC
                     VLTSWVIQHQAALYEVPVIEIEKVRIKEDHQLITGRLMNTNQKGESIYLSVPYQKNQI
                     ETANIKARQMYLVQMHGDEWQLVAKKNDGWLFFFTSIFIGAMLLIGGKHGLFALGSLI
                     INIVLLLLLLLIFTKIEGISLLNISILFVVIGMIISILALDGWNRSSIIKISAAVTSV
                     FLAFFICLLTMNLWKDQGLRYEELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATL
                     EELTKRQPEITAKQLWLSGRQVGRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKE
                     TIEQHLSLEFLRVIAGSLGIVLSIPISVLFFLTVRRLKR"
     gene            6614..7381
                     /locus_tag="ACG930_002040"
     CDS             6614..7381
                     /locus_tag="ACG930_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFQ0519196.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7481..9049
                     /gene="liaX"
                     /locus_tag="ACG930_002041"
     CDS             7481..9049
                     /gene="liaX"
                     /locus_tag="ACG930_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFQ0519197.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            9346..9666
                     /locus_tag="ACG930_002042"
     CDS             9346..9666
                     /locus_tag="ACG930_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFQ0519198.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9666..10016
                     /locus_tag="ACG930_002043"
     CDS             9666..10016
                     /locus_tag="ACG930_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFQ0519199.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10183..11121
                     /gene="hprK"
                     /locus_tag="ACG930_002044"
     CDS             10183..11121
                     /gene="hprK"
                     /locus_tag="ACG930_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFQ0519200.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            11136..11966
                     /gene="lgt"
                     /locus_tag="ACG930_002045"
     CDS             11136..11966
                     /gene="lgt"
                     /locus_tag="ACG930_002045"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFQ0519201.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            12010..13035
                     /locus_tag="ACG930_002046"
     CDS             12010..13035
                     /locus_tag="ACG930_002046"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFQ0519202.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            13050..13988
                     /gene="galU"
                     /locus_tag="ACG930_002047"
     CDS             13050..13988
                     /gene="galU"
                     /locus_tag="ACG930_002047"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFQ0519203.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            14113..14553
                     /locus_tag="ACG930_002048"
     CDS             14113..14553
                     /locus_tag="ACG930_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFQ0519204.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14556..15158
                     /locus_tag="ACG930_002049"
     CDS             14556..15158
                     /locus_tag="ACG930_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFQ0519205.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15217..16323)
                     /locus_tag="ACG930_002050"
     CDS             complement(15217..16323)
                     /locus_tag="ACG930_002050"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFQ0519206.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16533..17534
                     /gene="ccpA"
                     /locus_tag="ACG930_002051"
     CDS             16533..17534
                     /gene="ccpA"
                     /locus_tag="ACG930_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFQ0519207.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
BASE COUNT         5816 a         3078 c         3836 g         5082 t
ORIGIN      
        1 ttttctaacg gggccatttc tgagagtacg tcagaaatgg agaaagcgtc tcgcatgagc
       61 gaaattaact ttggggtatc tcttgttttt tggggaaagc aagaaataag ctaatatatg
      121 ctattaaaag agacacattt caaagccagt atagcataga aacttttaat gagatagttt
      181 tttttacaat tatgaggatt tattttgtta tttaatgatt ttgattcgtt ttcatcaagt
      241 aatgaaaatg ataaaataaa catactttag gattaaagga gatttctaat gaaaaaactt
      301 aaattattct taccaataat aggattagct attcttttat caggctgttc aaagtggatt
      361 gatcgaggag aatccattac ggctgttggc tcttctgctt tacagccttt agtagaaaca
      421 gttgctgaaa cttaccagac agaaaatcct ggaaaattca tcaatgtaca agggggcgga
      481 agcggaactg gtttgtctca agtacagtca ggagcagtcg acatcggaaa ctctgatttg
      541 tttgcggaag aaaaatcggg gatcgatgcc tcagcattag tcgatcatcg agtagcagtt
      601 gttgggatca ctcctattgt gaacaaggat attggcgtaa aagacatcag tatggaaaac
      661 ctgaaaaaac tatttacagg cgagatcaaa aactggagtg aagtcggtgg aaaagatcag
      721 ccagtagtta tattgaaccg tgcttcagga agcggaaccc gtagcacgtt tgaaaaatgg
      781 gtattggacg gagaaacagc tgttcaggca caagaacaag attcaagcgg aatggtgcgc
      841 cagatcgttg ccgacacacc cggtgcaatc agctatgttg ctttttctta tgtttccgat
      901 gatgtagata cgttgaatgt taacggtgta gaaccgacag atgaaaatgt gacaacgaac
      961 aaatggacga tttgggcata tgagcatatg tacacaagag atcatccaaa aaaactgaca
     1021 aaagaatttt tagactatat cttatctgat gaagtacaag ataacatcgt tggagaacta
     1081 ggttatatcc ctgtttctca tatgaaagtc gaacgtgatt ggcaaggaaa tatcgttaaa
     1141 gagtaatctt tacacaaaat ttacaaactt agctaaactt ttacatgtta ttaaaaccaa
     1201 attgatgttc aatttgtaca ctgagtgagt atgttaaacc tgattaaggg ggagtcatct
     1261 gtggaagatg tgaaaaaagt attattaaca aaatcaaaac gttcaaaaat ggaacagcgt
     1321 ggaaaattca tcagtttttt atgtatcgcg ctgatcgtgt tggttgtatt atctattttt
     1381 tattttgtag ctagtaaagg attggccacc ttttttactg ataagatcaa tgtatttgat
     1441 tttctgtttg gtacagattg gaatccaagc caaatcggag caaatgggaa accaatggta
     1501 ggggcattgc ctatgatcac aggttcgttt attgtgacct ttttatctgc tattgttgcc
     1561 acaccatttg ccattggtgc agcagtattc atgacggaga tctctcctaa aaacggaacg
     1621 aagatcttac agccggtcat cgagctgctt gtaggtattc cttctgtcgt ttatggtttt
     1681 atcggtttat cagttatcgt gccttttgtc agaagtattt ttggcgggac agggtttggt
     1741 atcttagctg gtacatttgt gttgttcgtt atgatcttgc cgactgtcac aacgatgact
     1801 gttgatgcat taaaggcagt accacggcac tatcgggaag cttcattagc gcttggtgcc
     1861 acaagatggc aaacaatcta caaagtcgtg ctacgagcag ccgtgcccgg gattttaaca
     1921 gcagtcgttt ttggtatggc tcgtgcgttt ggtgaagcct tagctatcca aatggtcatc
     1981 ggtaatgcag cattgatgcc aacaggactt actactcctg cttctacatt gacgtccatc
     2041 ttaacaatgg gaatcggaaa tacaatcatg ggaacagttg aaaataatgt gttatggtca
     2101 ttagcgctga tcttgctatt gatgtcatta ttctttaata tcgtgatccg tatgattggg
     2161 aagaaaggag agctgaaata atgaacgcaa aacgctcaga taaaattgct acaggtgttt
     2221 tatatgtagt ttcggggatc atcgtattga ttttagcagc tttactactt tatatcttag
     2281 ttcggggaat accgcacatt tcatggtcct tcttgaccga accttccaaa gcctaccaag
     2341 aaggcggtgg aatcgggatc cagctattta actcgattta tttgcttttg atcacgatga
     2401 tcatcagttt tcctatttct ttaggtgcgg gtatctatct ttcagaatat gctggaaaaa
     2461 actggctgac agatgtgatt cgcacgtcga ttgaaatctt gagctcattg ccttctgtcg
     2521 ttgtcggttt attcggtttc ttggttttcg ttattcaatt ccagtatggt ttctcgatta
     2581 tttctggtgc attggctttg actgtattca acttgcctct tttgactaga acagttgagg
     2641 agtctttaca agcggtccat tacacacaac gagaagcagg attggcttta ggtttgtcac
     2701 gctgggaaac agtgataaaa gtggtggttc cagaagcgac accagggatt ttgactggtg
     2761 tgatcctaag ttctggaaga atttttggtg aagcagctgc attgatctat acggctggac
     2821 aaagtgcacc tgcgttagat tttacgaact ggaatccatt aagtgtttca agcccgatca
     2881 gcattttccg tcaagctgaa acattagctg tccatatttg gaagatcaat acagaaggca
     2941 cgatgcctga tggtgtttct gtttcggctg gcgcttctgc cgtgttgatc attgctgttt
     3001 tactgttcaa cttcggcgct cgtgcgattg gcaaacgatt ataccgaaaa atgacttcag
     3061 cctaaggaga agaagcaaaa tgaaaaaata taactggaat gaaacaaatg tcatcaccat
     3121 gccaaaagag aaagaagtag cactatatac ggatgatcta catgtctggt atggcgacaa
     3181 tgaagcaatc aaaggagtgg atctggaatt tgaaaaaaat aagatcactg cactgattgg
     3241 tccttccggc tgcggaaaat ctacgtatct tcgttcgttg aatcgaatga atgatgggat
     3301 cgctaatacg aaaatcactg ggaaaatcat gtatcaaggc gtagatatta atgcgcctca
     3361 agtggatgtt tatgagatgc gcaaacggat tggcatggtt tttcaacgtc ctaatccgtt
     3421 cagcaagtcg atttatgaca atattacatt tgctttgaaa cagcacggcg aaaaaaacaa
     3481 aaagaaatta gatgaaatcg ttgaaacaag cttgaaacaa gctgccttgt gggaccaagt
     3541 aaaagacagc ttggacaaaa gtgccttggc tttatctggc gggcaacagc aacgtttatg
     3601 tattgctcgt gcgatcgcga tgaaacctga tatcttgctg ctagacgagc cggcaagtgc
     3661 tttggaccct atttcgacag gaacggttga agaaacactt gtaaacttga aagaagacta
     3721 tacgatcatc atcgtgacgc ataacatgca acaagcggct cgtatcagcg actatactgc
     3781 ctttttctat ctaggaaaag taatggaata tgacaaaact aacaagatat ttaccagacc
     3841 aaaaattcag gcaaccgaag attatgtgtc cggtcatttt ggttaagacg gaggcctcaa
     3901 catgacaaaa gaaattattt catctaaaga tcttcatctg tattatggaa agaaagaagc
     3961 actaaaaggg atcgatctaa gtttcaatca aggggaaatc actgcgatga tcggtccttc
     4021 tggttgcggg aaatccactt atctgcgttc tttgaaccgg atgaatgacc tgattccgaa
     4081 tgtaacgatc accgggagtg ttttatataa agacaaagac atctatggtc caaaaacaga
     4141 tgttgttgaa ctaagaaaag aaatcggcat ggtattccag cagccaaacc catttccttt
     4201 ttctatctat gaaaatgtca tctatggatt gaaattaaaa ggggaaaaag ataaaaaagt
     4261 ccttgatcaa gtagttgaag aaagcctgaa ggcagcgtct gtttgggatg atgtgaaaga
     4321 caaattgcat aaaagtgctt tatctttatc cggtgggcag cagcagcgtg tatgtatcgc
     4381 acgtgttttg gcagttaatc cggaaatcat cttattggat gaaccaacaa gtgcgcttga
     4441 tcctgtttct actgggaaaa tcgaaagtat gctgttagaa ttaagagagc ggtatacgat
     4501 gatcatcgtg acccataata tgtctcaagc ttcacgtatt tcagataaga cggcattctt
     4561 tttagatggt cacttgatcg aatacaatga tacgaagaag atattcatga atccagaaaa
     4621 acaagagaca gaagattata tttcaggtcg atttggataa ggaggaaacg gaatgctacg
     4681 tacacaattt gaagaagaat tgctgaatct ccataatcag ttctacgaaa tggggatgat
     4741 ggtgagcagc gccgtgcaca agtcagttcg tgcatacatc aaacacgata aaatcttagc
     4801 ccaagaagtt atcgaaaacg atataaatat caataacatg gaaacacgct tggagaagaa
     4861 aagttttgaa atgatcgcat tgcaacagcc agttacaact gatttgcgta tgatcattac
     4921 ggtcatgaaa gctagctcgg atttagaacg tatggccgat catgcggtgt ctgttgctaa
     4981 atccacgatt cgcgtaaaag ggcagacgag aataccggaa atcgaaaaag agatctccga
     5041 tatgtccgat tatgtgaaaa aaatggtgga caacgtccta gttgcttatg tcaaaacaga
     5101 cgaaaaagac gcacgtacga tcgccaatat ggatcaaaga gtcaatgact atttcaatcg
     5161 aatctataat gcaacaatca aaaatatgca ggaaaatcct gagacagtca tcagtggaac
     5221 agactacttg aatgttgcca gttatctaga acggatcgga gactatgtga caaacatctg
     5281 tgaatggatc gtctacttgg ctacagggaa aatcactgag ttaaatacga accacaatga
     5341 gattttctaa actaaagcgg tgattctgcc gtttgtttag gaaaagaggt tgtgaaatca
     5401 gcggttgtga aaaagctgtt ctgcatcaag taataagaac agtcaaacaa aaatagctcc
     5461 tcatattttt catttggctg gacttattac cgcagatgca agcttttgaa cactgtttat
     5521 tcgggaaagg gtttgtgaca aaatatgtca caaacccttt tcatcatttc atagaaagga
     5581 taaagaatgc aaaaaaaatt agcatcatca ctatattttt tatttgtgtg cttacttcat
     5641 gggttattca gcatcaagct gctttatatg aagtacctgt catcgagatc gaaaaagtac
     5701 gaataaaaga ggatcatcaa ttgattacag gaagactgat gaacacgaat caaaaaggag
     5761 aatcgattta tttatcggtt ccttatcaaa aaaatcaaat agaaacagca aatataaaag
     5821 cgagacaaat gtatctagtc caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa
     5881 atgatggctg gcttttcttc ttcacaagta tcttcattgg cgccatgttg cttattggcg
     5941 gaaaacatgg tctatttgct ttaggaagtc tcatcatcaa tatcgtttta cttttacttt
     6001 tgttgctcat ctttactaaa atagaaggga tttctctatt aaatatatct atcctgttcg
     6061 tcgttatagg gatgattatt agcatattgg ctttagatgg atggaataga agcagtataa
     6121 tcaaaatttc agctgcagtt acgagtgttt ttttagcatt ttttatttgt cttttgacaa
     6181 tgaatctttg gaaagaccaa ggactgcgct atgaggaact gaattatctg acacgaccgt
     6241 atcgttctgt ttttctttct agcgtactga ttggaacagc tggaggaaca ctcgataccg
     6301 ttatcacagt cattgcgaca ttagaagaat tgactaagcg acaaccagaa ataacagcga
     6361 aacagttatg gctttcggga aggcaagtgg gtcgagatgt gattggctcg atgaccaata
     6421 tccttttgtt cgtctatatc agtgggtcag ttccatcgct tcttttatat ttaggaaatc
     6481 aatggtcgtt caaagaaacg atagaacagc atttatcatt ggaattttta cgcgtcattg
     6541 ctggcagctt aggaatagta ttatcgatcc ctatctcggt cctctttttt ctgactgtaa
     6601 ggaggctgaa acgatgaatg tacttattat acttgttggg attttagcaa tcagcgtgct
     6661 acttattggc ggtacgcaag gtatgtatat tcttttaggc ttattcatca atttagggat
     6721 ctttttcttg ttgttattcg gttatcatca gaagtggccg atactggcat tgtcggtcat
     6781 aggattttta ttgattgctg tggttatctt attttttatc aacggttata atctaaaaat
     6841 gcgtgcagct tttgtgagta tactgatctt tttattttgt ttcctactat tgcttcctat
     6901 cactgatttt ttagcaatcc aaggttttac aacgatagaa ctagaagaat tatctggctt
     6961 agataagact ttagcgattg attttagatt acttacgaga tcgttgcttc tgattagtct
     7021 tagtggtgct gttttagatg cgagtgtagc aatttctagt gggacattcg aagtatatca
     7081 ggcaaatccg caattatctt tttaccaatt gcgccattct agtttcgcta ttgctaaaaa
     7141 aatattggcg tcaacagtaa tgacacttct ttttgcattc atgggaagtt ctttagcgtt
     7201 gatcctctgg tttattgatt tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt
     7261 tgttctagaa tatacgatgg ctattcttac cacattgtcc gcactacttg ttcttccttt
     7321 aacctgcgtg actacagcat atctctttac aaaaaagaaa gaacaactca agatggagta
     7381 aaagttacaa cttaagtcct atgacatttt tactgaatca gtgcataata tggatgtaag
     7441 gaaaagcttg caaacaattt tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat
     7501 tttagattta gtgaaaaaag gaatcctttc gactgaagaa ggcttagatt tattagaaag
     7561 catggcaact gaaaaagacg aaaagcaaat caaaaaagaa gcagacaagg taactgctag
     7621 tcataaagaa aaagatcagg caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga
     7681 aatttctgag ccagttgatc caaaggaaag agaaagacaa gatcaagaaa acttagaaaa
     7741 gatcttagat gaactagcaa ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa
     7801 tgctcaattc gctgacaata aggcagcacg caatgagaaa caggaagcat tgatgcagct
     7861 gaatacaaaa gaagaattag gcgagttgac agaagaagaa ttagcacagc gtcagacgtt
     7921 agaagcagaa atcaaagagt tagaagctag tggcgataca ctgttagaag aacaattgaa
     7981 attagaagca gaattaaaag atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt
     8041 tactgataag tttgaattgc cagatgattg gaaagatcaa gcaacagata cactgaatca
     8101 agtaggcgaa aaaatgtcag aagctggatc acagttagga aaattcttga agaaaacatt
     8161 ccaaactgtt tcagaaacag tgaatgacaa catggaatgg aaagatgtca gcttgcgtgt
     8221 ccctgggatt gcgacaacga aatttgagca tgaattttac tatgaagctc ctgcagcaag
     8281 tatccttgat atcaaggcag caaacggaaa cgtgacgtta aaaacgtggg acagcaacga
     8341 tgtgaaagtt gaagctaaga tcaaacttta cggaaaaatg ggtgctgaac catttgaagc
     8401 attctctgaa cggagccaga ttgaggttaa tgaagatcat atctccttcc aaattccaaa
     8461 taaacgtgtg cgtgcagacc ttgttttcta cttacctaaa cgagtatacg accacgcagc
     8521 tattaaactt ctaaatggca acatcatgat tgaaacattg gaagctaaag atatttatac
     8581 aaaatctacg aatggtaaca tcatcgtgga ccaattaact gcaacgatgc tggaagtaga
     8641 aggtgtaaac ggcaatatcg atattcgaaa cgggaacatc ttagattcta ttatcgaaac
     8701 agtaaatggt acagtgacat ttggtgcgac agcagaaaac ctttctgtgt ctttggtaaa
     8761 tggtgatgta cgtcttacga ttaaagaaga taatttgaaa aaagtagaag caagttcagt
     8821 gaacggaaat gtcaaagtcg ctttaccaga tggcatcggt ttggaaggac atgctaaaac
     8881 aagtcttgga agtatcaaca gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga
     8941 acggacaaac caaatgttgc aattccgtcg tgtttcagat ggtgaaatcg cgcaagtgca
     9001 actttcaacg acaacaggaa gtatctattt aaaagataca gataaataaa gaggttgtga
     9061 aagagatgtt cagccttgag caataagaag cgattttgta aaatagcttc ccctatttta
     9121 caaaattgtg ccttattgcc gataggctat ctcttgaaca ccgtttacca agagattatg
     9181 aacttgccaa ttatcgccga gtcacaagga ataatttcaa aaaaagctcg tcacgtttta
     9241 tgaatatggt aatttgtgac cgagaatttt gcaaaaagac accgattaag aagaaggttg
     9301 tcacaacgat tttcttcatt taaaatagta gaacagaggt gagacatgat gaaaaaaaag
     9361 ttgacaaaat ccaataaaaa tgttgttttg acagggactt tagcaggaat aggagaatac
     9421 atcgggattg atccgactgt tatccgtgtg ctttatgtat tcctgagctt agttgctttt
     9481 ggaagtccaa tcattttata cattttatta gctttgatta tcccatctgc gcgttctgca
     9541 cgaacaaact atggacataa caatgcatat tatgaaaaaa acaattatcg tgaacaaact
     9601 cgtgaacaaa caaaaaaacg caaagaagcg gaaaaaatcg atgatgacga atggagtgac
     9661 ttttaatgtc gtactttcaa cgtattttag ttaatacgtt aacattcata tcattggctg
     9721 ttctttttcc tgcgatggtc catgtgagca gtatttggac ggccgttctt gccagcttcg
     9781 tattgtctgt gttgaatatg tttgtcaaac cgattttgac gatactgtcc ctgcccttta
     9841 cattagtcac attgggattg tttacgtttg ttatcaatgc agcgattctt aaaatgacct
     9901 ccttttttgt gggagcagaa cattttagtt tttcttcatt cggtgcagcg ttgttagtag
     9961 ctatcttgat gtcgcttgtc aatgtaattg tcagcgaaca taacagtaga aaataaaaga
    10021 aagctgtgcc gaactatcgg cgcagttttt ttatttagaa tcaggaatgc gttttctatt
    10081 acattggtaa ttaaataaaa acgttttttt taattggtag tacttttggc tagacaatga
    10141 taaaatgata gagaacactc taatagaaat gaggtagcat gaatgtcaga agttgtaaaa
    10201 gttagccaat tagtgaaaaa attatctttg gaaatcgtga caggcgacga gaaaagctta
    10261 gaccgtgtca tcgtaactgg ggacatctca cgcccaggac tagagttgac tggttatttt
    10321 aattattatt cccataatcg tttacagcta tttggcagta aagaaatcag ttttgcggaa
    10381 cggatgatcc cagaagagcg tttgatcatc atgagaagat tatgtagtga agatatgccc
    10441 gcatttatta tttcaagagg attaccagct ccagaagaaa tgatccaggc agcaaatgaa
    10501 aatgggatag ctgtactgcg ttctcccatc tcaacttctc gcttattagg agaattatcc
    10561 agttatttag atggtcgcct tgcccctcga acaagtgtcc acggtgtttt agtggatgtt
    10621 tacggattag gtgtactgat tcaaggtgac agtgggatag gaaaaagtga aacagcgttg
    10681 gagttgatca aacgcggtca tcgattgatc gcagacgatc gagtagatgt ttatcagcaa
    10741 gatgaattaa cggtgatcgg agaaccgcct aaaatcctgg aacatctgat tgaaatccga
    10801 ggaatcggga tcattgatgt aatgaatctt tttggtgcga gtgcggtacg tggctctatg
    10861 caagtccagt tggctgttta tctggaagca tgggcaaaag ataagaaata cgaccgtctg
    10921 ggctctgaag acacgaccgt tgaaatcgcg gaagtaggca ttccacaaat aaaaatccct
    10981 gtcaaaacag gacgaaacgt tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca
    11041 cgtacaatgg gctttgacgc aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa
    11101 gaaaactcag gcaacgacta gcaaggagtg acaatatgtt agcacaaatc aatcgagttg
    11161 cttttgagct tgtagggatt cctatctact ggtatgcatt gatcatcgta tcaggtatca
    11221 ttatcgccat gtggcttagc agcagagagg ctgttcgggt aggattaaaa gcagatgatg
    11281 tgacagattt tatgttgtgg ggattgccta tctccattat tggcgctcgc ttatattatg
    11341 ttttatttga tcttccccag tatatagctg atccaatcca aatattcaat atccgttcag
    11401 gaggcttagc tatttatggc ggactgattg caggcgcgat cacgctgtat ttttttacta
    11461 aatatcattt tatttctttg tggacttttt tagatatcgc tgcaccaagt gtattattag
    11521 cacaagcaat cggtcgttgg ggaaatttca tgaaccacga agcatatgga ccagacacga
    11581 cgcgaagctt cttagaaagt ctgcatttac cgcaattcat cattgataat atgtatatcg
    11641 aagggatcta tcgtcaacca acatttcttt atgaatcact ttggagtttg attggattta
    11701 ttttgctttt gtttttacga aagaaaccac accttttgaa aaaaggtgaa gtccttttat
    11761 gttatctaat gtggtatagt ttcgggcgtt tctttattga aggattacgt acagacagtc
    11821 tttacttttt aggtgtgatc cgtatttctc aattattatc tgctgtgtta tttgtcggta
    11881 cattgattct atttatttgg cgcagaaaaa aaggaaattt accggattat gaccgctcat
    11941 taggaaaaaa tcaacaaatt atctgatttt tagagcgtta aaaatgaaaa aaatttcagg
    12001 agtggtaaaa tgaattatag agtagcggtt ttaggaccag gctcttgggg tactgctttg
    12061 gcacaagtcc tcgccgaaaa cggacatgac gttcggattt ggggacatcg tgcttcacaa
    12121 gtagaagaaa tcaacaccca acacacgaat caacgttatt taccagatca ttgtctaccc
    12181 gattccatcc aagcattcac caatatggaa gatgcagtaa aagacgcaga tgcggtgcta
    12241 ttcgtcattc caacgaaagc aatacgttct gttgcaaaag aactagtgcc taaattgaat
    12301 acaaagccag tgatcatcca tgcaagtaaa ggattagaac aggggacaca taaaaggatc
    12361 tctgacatct tgttagagga aatcccagta gaaaaaagaa aagctgttgt tgttctttct
    12421 ggaccaagcc atgcagaaga agtagcgaaa catgacatca ctacgatcac agctgcaagt
    12481 acagatgcaa aagcagcaaa atatgtacaa gagctgttca tgaataatta ttttcggatc
    12541 tataccaatc ctgatgtgat cggtgtagag atgggggcag ctttgaaaaa tattattgct
    12601 attggtgctg gcgctattca cggcttaggg tttggcgata atgcaaaggc agcaatcatg
    12661 acgcgcggat tagctgagat cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc
    12721 tttatcggat taagcggagt aggcgatcta gtcgttactt gcacaagtgt tcattctagg
    12781 aactggcgcg caggcaactt gttaggacaa gggcagcccc tagaagaggt gctagccaat
    12841 atgggaatgg tcgttgaagg tgtgaatact acccaagcag cgatggaact agcccaaata
    12901 atggaaatcg aaatgcccat cactcaaaca atctatgaag tgctgtatga acaaaaagaa
    12961 atcaaaacag ccgcaaaaga aatcatgtta cgtgatggga aaaaagaaaa tgaattctca
    13021 ttaacaattt tttgaaggag cgaatgtata tgaaagtcaa aaaagcagtt attccagcag
    13081 caggattagg aacaagattt ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa
    13141 ttgttgataa accaacaatc cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag
    13201 acatcttgat cgttacagga aaagctaaac gaccaatcga agatcacttt gattcaaata
    13261 ttgaattaga aacaaaccta agtgaaaaag gaaagaccga attattgaaa ttagtagaag
    13321 aaacgacaga tgtcaacttg catttcatcc gtcaatctca tccaaagggt ttaggacatg
    13381 ccgttcttca agcaagagcc tttattggaa atgaaccatt tgtcgttatg ctaggcgatg
    13441 atataatgga agacgaagta ccattgacac agcaattaat cgatgattac gaacgtactc
    13501 atgcttctac gatcgccgtt atgcaagttc ctcatgatga aacttcaaaa tacggaatta
    13561 tcaatccagg agaagtattg gaagatgggt tatacaatgt caaaaacttt gttgaaaaac
    13621 cagatccaag caaagcacca agtgatttag ctattattgg acgttactta ttgactccag
    13681 aaatttttga tgtattgtcc gagcaacaac caggagccgg aaatgaaatc caactaactg
    13741 acgcaatcga tacattgaat aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac
    13801 gttacgatgt cggtgacaaa tttggtttta tgaaaacaag tattgaatat ggtctaacac
    13861 atccagaagt aggtgcacct ttacgtgagt acatcctgtc tttaggtaaa acattagaag
    13921 cagaaggaag caagatcgat cataatccaa aaggaataac agaaatcaaa gaagaaaaga
    13981 aaaaataacc cttttttcta acgagcttca gctgctaatt gaataaaaag tagttgaagc
    14041 tcgtttttat ttgtttaaaa aacacgaaaa tgctatcctt atagaaaaga gagacaagaa
    14101 gggagtttga tcatgtcagg aggagaaatt gcaggattga tcgcagcaat cgcctttgcg
    14161 atacttgtcg tttttatcgt tcgtgtgttg ttgcaagttt ctaaaacttt agaaaaagta
    14221 gatcagactg tagcagaagc aaatacgacg atcgaaatcg tcacaaaaga cgtagatctt
    14281 ttgtctagac aagtagaagg cttactggtc aaaagtaatg aactgctctt ggatatcaat
    14341 ggaaaagtcg caacgatcga tccattgttc acagcagttg ctgatttaag tgaaagtgta
    14401 tcagaactta atcattctag taaaaacatc gcgacgaaag tcggcggaat cggtaaaacg
    14461 acagctaaag cgacggttgc cggaaaagtc ggtgggacag cgatgaaatt ttttaaaaac
    14521 aaaaaacata ctgaaacgac aggaggaaaa taaaaatggc taaaaaaggt ggatttttat
    14581 taggtgcagt agtcggaggc acagccgcag caatcgccgc gttattgtta gcaccaaaat
    14641 ctggtaaaga acttcgggat gaattagctg cccaagcgga tgatttgatg gatatggctt
    14701 cagattacac agatatggcg aaagaaaaat cgactgagtt aacaggtatt gcaaaagaaa
    14761 aagcgcaaga tctttctcaa caagcaggtg atctagcagg tagtgtcaaa caaaaagtaa
    14821 gtgaatcagc agatgaagca ggaagtgaat ctgacgatat cttgttaaat cttaaagaac
    14881 aatcagctga cttatctaat cgtttcaaaa aaacggcaga agatatgaaa aaacctgcag
    14941 atgaattagg aagtattgct aaagatactt cagaagatat cataattgat gtaaaagacg
    15001 ctgctggtaa agcaggagat actgtcaatg aaggaatgtc agaagcaaaa ccagttgcag
    15061 atgactcaaa agaaatgatg aaaatggcaa aagaagatgc gaaagaagct aaaaaagaaa
    15121 taaaagatac aatgacagat tcatctacaa atcactaaaa tcacaaattt atagaataaa
    15181 aaggtgggag cggactagct ctcacctttt ttactcttat ttttctaaaa caagtaattc
    15241 ttttggtgta gtcgtgaatg gcacacagcc atcgcttgtc acatatacac agtcttcgat
    15301 acgtacccct actttttcag gaatatagat tcctggttca agagagaagc acatcccttc
    15361 ttcgattact aagtcatttc cttctacaag ggaagggaat tcgtggacgg ttgttccgat
    15421 cccgtgacct aaacggtgat tgaaatattc gccgtagcca tagctgttga tcacgtttcg
    15481 tgcgatttga tcaagttcac ctgctgtcac acctggacgg acggcttctt gtgcggcaag
    15541 ctgtgcttca agagtgatgt tgtagatttt ttcttggaag tcggttggtt tttgataagc
    15601 aattgtacga gtagcatcac tgcaatagcc attccaaaca acgccaagat cgaataacac
    15661 aagttcattc ggtgaaatct tcgtatttcc tggtgtacca tgagggcttg cagcatttgc
    15721 tcctgcaagg actaatgtgt cgaaagacat ttgtgaaaca ccttgttttt tcaattggta
    15781 ttcaatttct gcaatgatcg cttgttcagt cacgccttct ttcactgctt taaagccaat
    15841 ctcaaatgca acatcggccc atttaccagc ttcgatcagt ttgtcttttt cctctagagt
    15901 tttgatcagt tgtagacgtt ggatgatgga agttagatca gtgtaagaat ccgttcccgt
    15961 caagatatca gagatagcat cgaagcgctc gacagtcaag gcgttctttt caatccctac
    16021 attgccaggc tgaccatagc gagtacgaag ttcttttccg atgatctccc aagggttttc
    16081 gctgtctaaa tagccgcgga catcatacgc ccaactactg ttttgagcat cttcaacttc
    16141 caaagcagga gtgaaaagga aaggatcttg ttcaagaggg ataaaaagag ctagtacacg
    16201 ctcatgagga tcactttcgt atccggaaaa gtaagcgatg tggccagggt cgctgatata
    16261 agccaattcg acttggtgtt gtgccatcca ttgacgtagt tcattgattt ttacgttatt
    16321 catttggcaa cctactttct aaattaattt tgtattcaat aattgtacca ctgatttatt
    16381 aaaagaccaa cgttctaaaa actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa
    16441 cggttgcaat tcttgagatt atttgatatt ctattttaga aatgtaagac gtattttcag
    16501 aaaacatata aaatatgaat gggagaacac aaatggaaaa gcaaacaatc actatctatg
    16561 atgtagcgag agaggcaaat gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc
    16621 caaacgttaa accagcaaca agaaaaaaag tcttggaagt catcgatcgc ttggattatc
    16681 gtccaaacgc agttgcgcgt ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca
    16741 tccctgatgt cagcaatatg ttctttgctt ctttagcacg tggtatcgat gatgtggcaa
    16801 caatgtacaa atacaatatt atcttagcaa attcagatgg caacgaccaa aaagaagtca
    16861 atgtattgaa taacttactg gctaagcaag tggacggcgt gatcttcatg ggtcaccata
    16921 tcacagacga aatccgtgga gaattttcac gttcaaaaac tcctgttgta ttagctggct
    16981 ctattgatcc agatgaacaa gtaggtagcg taaacattga ttatgtatcc gcaacaaaag
    17041 atgcagtaaa taaattggca aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt
    17101 tgatcgatcc tatcaatgga caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa
    17161 ataacctacc atatagcgaa ggattgatct ttgaagcaca atacaacttc aaagatggtc
    17221 tatctctagc cgatcggatc cataatagcg gtgcaacagc tgtctatgtt tcagatgatg
    17281 aattagccat cggtattttg gatggtttat tagatcgtgg cgtgaaagta ccggaaggat
    17341 tcgaaatcat cacaagtaac aattcactac tgacagaagt agctcgtcct cgtttaacaa
    17401 gtatcacaca accattatac gatttagggg cggtatctat gcgcctattg acgaaaatga
    17461 tgaataaaga agaagtcgaa gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag
    17521 gatctacaaa ataataaaag gacaaccatt cagaggttgt gagcctgccg tttaactctg
    17581 cgttacaagg agcaatttca aaaaacagca tttcatgttt gatgaatatt gtgactcgtg
    17641 attcggagtt ggcaggagaa caccgtttat tcgggaaaag gggttatgac aaaattttgt
    17701 tataatcctt tttttgtgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta
    17761 tataaaacaa tccgtgtata gatgctgcat tttgttcacc accatcaaaa aa
//
LOCUS       DAZKPE010000054        17403 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000054 DAZKPE010000000
VERSION     DAZKPE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.054"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..563)
                     /locus_tag="ACG930_002052"
     CDS             complement(<1..563)
                     /locus_tag="ACG930_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HFQ0519208.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="ACG930_002053"
     CDS             complement(750..1400)
                     /locus_tag="ACG930_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519209.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="ACG930_002054"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="ACG930_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFQ0519210.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /gene="yvcK"
                     /locus_tag="ACG930_002055"
     CDS             complement(2912..3910)
                     /gene="yvcK"
                     /locus_tag="ACG930_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFQ0519211.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="ACG930_002056"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="ACG930_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFQ0519212.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="ACG930_002057"
     CDS             complement(4926..5657)
                     /locus_tag="ACG930_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFQ0519213.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="ACG930_002058"
     CDS             complement(5661..6926)
                     /locus_tag="ACG930_002058"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFQ0519214.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="ACG930_002059"
     CDS             complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="ACG930_002059"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFQ0519215.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="ACG930_002060"
     CDS             complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="ACG930_002060"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFQ0519216.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12268..13770
                     /locus_tag="ACG930_002061"
     CDS             12268..13770
                     /locus_tag="ACG930_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFQ0519217.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13772..14509
                     /locus_tag="ACG930_002062"
     CDS             13772..14509
                     /locus_tag="ACG930_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519218.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14680..15873)
                     /locus_tag="ACG930_002063"
     CDS             complement(14680..15873)
                     /locus_tag="ACG930_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0519219.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(15952..16158)
                     /locus_tag="ACG930_002064"
     CDS             complement(15952..16158)
                     /locus_tag="ACG930_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFQ0519220.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(16151..17293)
                     /locus_tag="ACG930_002065"
     CDS             complement(16151..17293)
                     /locus_tag="ACG930_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0519221.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
BASE COUNT         4965 a         3742 c         2988 g         5708 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
     7141 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
     7201 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
     7261 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
     7321 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
     7381 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
     7441 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
     7501 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
     7561 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
     7621 ttctacagca tcctctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
     7681 cacttctaat gtttcagaat tatatcgttt accatgacat acttcacaag gaacatagac
     7741 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
     7801 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
     7861 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
     7921 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
     7981 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
     8041 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
     8101 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
     8161 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
     8221 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
     8281 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcaa
     8341 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
     8401 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
     8461 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
     8521 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
     8581 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
     8641 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
     8701 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
     8761 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
     8821 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
     8881 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
     8941 gaaaagatca tctgtcccat tcaagatgat ctcctgatgc tcttccggta attcttcgaa
     9001 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
     9061 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
     9121 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
     9181 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
     9241 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
     9301 cagagcatag ccgtctgcta atcgcagggc cgcctctaaa gaatcaaata ggcgagaacg
     9361 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
     9421 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
     9481 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
     9541 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
     9601 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
     9661 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
     9721 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
     9781 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
     9841 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
     9901 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
     9961 gttatgggca cgtgcaccat gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    10021 tgaagctttt aattctaaaa tcatatctcg cacattcgcg gctgtttcaa aatccaaagc
    10081 ttttgccgca tctttcattt ctttttctaa tttcatcaat aacgtgtctt tttcttcctt
    10141 cgtcatttct tcgtacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    10201 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    10261 attgtacttc tgctgaatcg tacgacgtct tgacgtttca tccatcgcta gacgcataga
    10321 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    10381 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    10441 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    10501 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    10561 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    10621 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    10681 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    10741 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    10801 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    10861 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    10921 ttttctcgct cggtcaccat tatacattcc tctgatttga ggcatggtta cgtgcgattc
    10981 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    11041 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    11101 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    11161 gttttcattt cgcaagacag ttaaacgctg ttctaattcc tctttgatat tcgctacggc
    11221 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ctacgtgttc
    11281 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    11341 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    11401 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    11461 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    11521 tacttgtttt tggtactcaa aaggcgagcc taatccaaaa atacatgaaa cggatgcaat
    11581 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    11641 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    11701 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    11761 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa tcagtgttgg
    11821 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    11881 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    11941 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    12001 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    12061 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    12121 acttttttat cttattatac atgttatgtt ttataacata aaatgttaga aactcgcatt
    12181 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    12241 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    12301 ttcttaatga caggacttgt gacacttgcg tttggtcatg ttgcacaagc tgacaacact
    12361 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    12421 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    12481 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    12541 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    12601 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    12661 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    12721 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    12781 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    12841 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    12901 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    12961 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    13021 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    13081 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    13141 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    13201 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    13261 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    13321 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    13381 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    13441 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    13501 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    13561 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    13621 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    13681 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    13741 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    13801 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtatcca tcaacgaagg
    13861 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacattct tgcgttgctt
    13921 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    13981 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc aacactttaa
    14041 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    14101 agaatctaga gaagaagcag agaaaaaagc aatcaaatta ctgcagacag ttggtctaga
    14161 agataaaaaa gatatgtatc ctgaaatgct ttctggtgga caaaaacagc gtgtggctat
    14221 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta cttctgcact
    14281 cgatcctgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    14341 gacgatggtt atcgttacgc acgaaatggg gttcgctaaa gaagtggcca atcgcgtcat
    14401 gttcattgac gacggaaact ttttagaaga tggaacgcct caacaaatct ttgaaaatcc
    14461 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaaa ataaattata
    14521 tatgtctttt tgactatctt tttatatctt cttaaatgtc cgcaaagcct tattttatag
    14581 gctctacggg cattttgctt ttgtggtaaa cctcacatat ctaggtctat cttcttatat
    14641 tttcactatc aagcgtggtt aaaatcgtgg taaatacttc tatgcaatta gacgctgaac
    14701 ctctgatttt gcggtatcta tggacgcatg agcataccag ttcattgtga tactgatatt
    14761 tgaatgcccc atgatatact gtaaatcttt tgggttcatg ttcttgcttg ccagtcttgt
    14821 gcagaatgta tggcgtagcg tatgcggtgt gatatgtggc aatggattgt ccttgtggtg
    14881 cttgttgtat ttctttacca tacggataaa taaggcgtta taatcaatcg caactttggg
    14941 cttgccctta tgattgacaa ataggaagtt gccccgtccg tctatcacaa atggttctgc
    15001 ctttggacgt tttttcataa cctgttgaaa tgcctgtatc gtttctttgc ttaatggtac
    15061 ttgccttatt ccgctttttg ttttaggcgt ttcaatataa tagccctgtt ccttgctctt
    15121 tagtaactgg tggtcgataa tcacaacttc attcttgaaa tcaatgtcgg ctactgtcag
    15181 tccgcacagt tccgaaatac gaagtcctgt ctttaacagt atcagcacat catcataatg
    15241 cttgtgatac acattgtccg tcttgatgaa tgagagtaag gcttgttcct gttcctctgt
    15301 caatgcgact ttctttttgg tatcattttc taggacttca ctcaacttga aatcaaaggg
    15361 atttttcctc acataatcat cttgaatggc tatgtagaat gacgctttta acgagcgttt
    15421 atggttgtta atggtattgt aggaaaagcc tttgtctttc atgcgtaacg cccattcctt
    15481 agcgtcagag ggtttgattg tatcaatgct cctagcacct aacttgtcct ctttcaataa
    15541 ccgcatgagt tgttcccgtt gtttctgtgt gcttttcttc acatttgccc tctgtgcgtt
    15601 ctgtttggca taaagttggc aaagcgtcat tttcttgcca gtgctgtcga taccgtcctc
    15661 aatatcccgt cttatctgct gttccagttc tcgaagtgag ggtttttccc gttttccctt
    15721 tggtgtcggg tctgtgggtg tcaatctcca agcatacaca tattttgtgt ttccaaatgc
    15781 gtctacatat ttatataagt attttctgtc tgttcgttgg ctctctccag tatgcaggat
    15841 acgacctttg ttatcccgtc ttttttcttt catggtgtct gctcctttcc ttgttggaaa
    15901 gagccttgat atgacttgtg ttcatcataa cacatacaag gctcatttgc attagatagc
    15961 gtccaattta tcaatgacct gttcaaactg tcggcgttta atctgtatgc ggttgccatt
    16021 cataatgagc cagccagcgt ccttgttttc ctctgccaat cgtcttaact tgttttctcc
    16081 gatacggaaa tactttgacg cttcttcaat ggtaagggtg tatttttccc atacgggaat
    16141 atcctgtgca ttactcataa aacaccccct cactttcgat tacgtctgct atgtccgtac
    16201 acatctgttc cacaagcatt tcctgctttt cagagaggtg ggtacattca tcaatcattt
    16261 tcatgtagtt tgagcctgtc agcctgtcga tttcctctat catcacgatt gacggcatga
    16321 cctgtctttc cagccattgc agagtgcgtt ccatattgac aggtacgggg ttcatttcaa
    16381 aaggtaaact gtcatgggaa atgaatatct cccacagcgg atagtcggga aattgcacaa
    16441 aatcagtaat aaggtaaaac accagcccat gagggttata tgtcaataac aattcctcaa
    16501 ctgcctgtac tgcttttgta ccacgcagac gaatttcaaa acgattgata atatccgtat
    16561 gtttcttttt ggttgcctgt tccttttgtt tttcatacag gcagaagtat tttgtgcttg
    16621 cctttgaacc gatataaagg gtgcttgcta aattacggtt ttttccgctt agttttccac
    16681 cctgcacatt ttcataattt ttacagcgac aatccgcacc gccatttctg tatttttcag
    16741 acaaaacggg aatatccaac agaccacaca tatcattgat tgccaagtca aaacgtcgga
    16801 taacaccgtc acagtcaaga cagcggttta aaaatgaata ccaatctctg ttctgtgcct
    16861 gcaagacata ttccatgttg cgtgagcctg ccccttttaa ttccaagaat acgcccatgt
    16921 gttcgtcatc agaagccatg accttgattt ctccgtaggc gtaatgctct ttatagccat
    16981 aatacccata gtcataatgg ataaaataat ctgctttcat gccaagcacc tttcggataa
    17041 tttccaatgc gtcagtcgtt ggataacgga cagacagata atcaacgagc agataaaaag
    17101 gcttatcgca gatataataa ttcagacaac gcaggataat attttgtgtt tccttgctgg
    17161 cgttggcttt tccgttctca aagcggttga tactatatct tgatacatgg gtaagacttg
    17221 caagttctcc ttgtgaaaga ccgcttgcaa gacgtttgtt cttcatttca agtgcaaatt
    17281 ctaaattgtt cattgtattc ctccaatccc acaatagcct tgaaatacct gtaaacctct
    17341 attcaaaaag tgtgatatgc actatcttct taaaacttct cattactact cacaactttg
    17401 gga
//
LOCUS       DAZKPE010000055        17168 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000055 DAZKPE010000000
VERSION     DAZKPE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.055"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(543..2048)
                     /locus_tag="ACG930_002066"
     CDS             complement(543..2048)
                     /locus_tag="ACG930_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0519222.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ACG930_002067"
     CDS             complement(2045..2731)
                     /locus_tag="ACG930_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0519223.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACG930_002068"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACG930_002068"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFQ0519224.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4515..4694)
                     /gene="rpmF"
                     /locus_tag="ACG930_002069"
     CDS             complement(4515..4694)
                     /gene="rpmF"
                     /locus_tag="ACG930_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFQ0519225.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4752..5321)
                     /locus_tag="ACG930_002070"
     CDS             complement(4752..5321)
                     /locus_tag="ACG930_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFQ0519226.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5507..6409
                     /locus_tag="ACG930_002071"
     CDS             5507..6409
                     /locus_tag="ACG930_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0519227.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6444..8228)
                     /gene="pyk"
                     /locus_tag="ACG930_002072"
     CDS             complement(6444..8228)
                     /gene="pyk"
                     /locus_tag="ACG930_002072"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFQ0519228.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(8302..9264)
                     /gene="pfkA"
                     /locus_tag="ACG930_002073"
     CDS             complement(8302..9264)
                     /gene="pfkA"
                     /locus_tag="ACG930_002073"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFQ0519229.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9432..12746)
                     /gene="dnaE"
                     /locus_tag="ACG930_002074"
     CDS             complement(9432..12746)
                     /gene="dnaE"
                     /locus_tag="ACG930_002074"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFQ0519230.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            12977..13162
                     /locus_tag="ACG930_002075"
     CDS             12977..13162
                     /locus_tag="ACG930_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFQ0519231.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(13224..14420)
                     /locus_tag="ACG930_002076"
     CDS             complement(13224..14420)
                     /locus_tag="ACG930_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFQ0519232.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14590..16026)
                     /locus_tag="ACG930_002077"
     CDS             complement(14590..16026)
                     /locus_tag="ACG930_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFQ0519233.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            16319..17128
                     /locus_tag="ACG930_002078"
     CDS             16319..17128
                     /locus_tag="ACG930_002078"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0519234.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         5039 a         3591 c         2982 g         5556 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attttttatt
     4441 taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt tttacatttt
     4501 ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata gtaaccacaa
     4561 tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc gtttaaccct
     4621 ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga tgttcttcta
     4681 gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat tagacacaat
     4741 atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag ttcagatagt
     4801 tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg ctggtattct
     4861 tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc ttcctcttct
     4921 tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga ctctgctaaa
     4981 ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc atctctactt
     5041 tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg cagttcaaca
     5101 ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta atgaacgata
     5161 tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac atcaagtatt
     5221 aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa agttaacggt
     5281 gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca ctcctaagca
     5341 acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt gacaccttgc
     5401 agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat catcctcaga
     5461 atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga acacgaaaga
     5521 tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg ctaattattt
     5581 ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag agtttgacac
     5641 cgtacttatt acaagagatc gatcgcatca cgaattgatc gtcacgcctt ctggaaagca
     5701 gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag ctgaaatcac
     5761 tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca atgaatactt
     5821 tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg agattaccga
     5881 tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt tagctgtatt
     5941 aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt tggacaaacg
     6001 tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg tctctttcaa
     6061 agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc ccgcagcatt
     6121 cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa gcaatgactt
     6181 gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg cagagattgc
     6241 tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc agcctcgctt
     6301 cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag aacaagtagt
     6361 ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa agaagagctg
     6421 tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta aacgatgccg
     6481 cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc gcctttagca
     6541 ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga agtcaatccg
     6601 ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc tttgtcagtt
     6661 gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc agcagatgaa
     6721 gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc taataattta
     6781 gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac tggtacacca
     6841 gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc ttttttagct
     6901 gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg gtaaacgccc
     6961 cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa gatatctgca
     7021 tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc agcaacgatt
     7081 gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt ttcagttaca
     7141 tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc attttcagct
     7201 tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc gtttgcagat
     7261 tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac gtcagaagct
     7321 tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt agcagtgata
     7381 actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat tggtactagt
     7441 tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc agaaactttg
     7501 atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa gatttgaaca
     7561 tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg tgctttacgt
     7621 acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat atcgtcagca
     7681 tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac ccctttacgt
     7741 gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc ttcgtctttt
     7801 tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc aacgtgaaca
     7861 tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac atgttcagga
     7921 tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc acgaccaaaa
     7981 tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt atctaaaaga
     8041 ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat acgtgataat
     8101 tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc agattcaatc
     8161 aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac gattttggtt
     8221 tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta cacagcttaa
     8281 atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat atagtgataa
     8341 gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa cgatttcgtt
     8401 gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga cagcgtaagc
     8461 accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac ggacaacgtg
     8521 tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct cagcgaattc
     8581 atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc cgcgatcgcg
     8641 gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg ggatgatgat
     8701 ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat tgcgtcccat
     8761 tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac ggtcaattga
     8821 ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc caggaatatc
     8881 attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca aagccattgc
     8941 gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga attttttcaa
     9001 ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac gtgcagaata
     9061 caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa gacgacgaat
     9121 atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca gtccttcgta
     9181 aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt ctccgccact
     9241 ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac tttatcctaa
     9301 gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct aacattattt
     9361 ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca agtagtattt
     9421 tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat aagttgccgc
     9481 tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt tcgttgcgtt
     9541 ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat cacttgtaat
     9601 tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca agtttgtgaa
     9661 ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag ttgcagttcc
     9721 tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc aacggcaaac
     9781 aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc tccactactg
     9841 tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc tctaacttcc
     9901 ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat cagctgaact
     9961 tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa ataaatacct
    10021 aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac ttcttcttct
    10081 tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat attttggatt
    10141 tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc aaaaactcct
    10201 actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat ccgtatgagg
    10261 aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat atcttctaca
    10321 aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc cttattgacc
    10381 aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag tttattttta
    10441 cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga attcatcagg
    10501 ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa tcccacgaat
    10561 gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc gatatattca
    10621 tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga tacaaaatgc
    10681 gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg cagaatatct
    10741 gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg ttcctgatag
    10801 acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg gtagcgaatg
    10861 gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg gcctggtcga
    10921 tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct tcgtaaaacg
    10981 ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg ttgaaacaag
    11041 agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata cccttctact
    11101 cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc taaaaagtcc
    11161 attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag aaaagcttca
    11221 tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat aactacacct
    11281 gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt tttgaataaa
    11341 agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt tttataagct
    11401 tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt tgcttcactt
    11461 tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc cattgtgcca
    11521 aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata attcaatact
    11581 tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa gcgttcgggg
    11641 tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt gatttctaac
    11701 acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac gattttgttt
    11761 ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa tcccatttga
    11821 tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata gtcagtgatt
    11881 cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg ttttccatta
    11941 ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga aatcgattca
    12001 gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa tcgtttgatc
    12061 atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc agataaattt
    12121 tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc aaaaagttct
    12181 tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc ttttatcaca
    12241 tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat ataaaaattt
    12301 ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc ctctttattg
    12361 aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc ggtttctgtc
    12421 atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt catcagctgc
    12481 tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc ttcataagta
    12541 taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat acgatagaat
    12601 tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta gccttgtttt
    12661 tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga ataagaagta
    12721 attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt taaaattcac
    12781 tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg aagttgatta
    12841 ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa gaactcaaat
    12901 tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa attaagatag
    12961 aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg ttctaggtca
    13021 agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta ctttgacaac
    13081 aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg cgccaagaaa
    13141 agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc aagctctttt
    13201 ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg aaagttgaat
    13261 aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac agcactgtaa
    13321 ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc aaagttgcta
    13381 aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat cttactgatc
    13441 agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa gcgaagtata
    13501 cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa tgataaaatg
    13561 agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc tagtttcggt
    13621 gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac aaaaaggata
    13681 ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct gatcgtagtg
    13741 attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga gagatgatcc
    13801 atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg atggaaatct
    13861 tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc tgtgatcaag
    13921 aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg tccgatcaga
    13981 tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt ttctctaggt
    14041 gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat cccattccaa
    14101 aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc cattgttaat
    14161 gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc agctagattt
    14221 ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc tagtcccgaa
    14281 aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg tatgaatggc
    14341 ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat cactaaattt
    14401 tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat acctattttc
    14461 gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag gtcattttat
    14521 atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt tccaatccct
    14581 tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa tatcaacgat
    14641 ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa ttgtatagaa
    14701 aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa agatcgatgc
    14761 aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa aagaagccat
    14821 catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta caatggcgat
    14881 cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg aagtcaaacc
    14941 agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg tattcgatgt
    15001 accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt tatccatttt
    15061 tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga aaatacctgt
    15121 gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata aactgaatgc
    15181 gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag attgcatgcc
    15241 ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat tacctaacga
    15301 attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac caaggactgt
    15361 ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta aaatggctgt
    15421 cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg ctaacgcagg
    15481 gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga cagagctcga
    15541 aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc cgacatacgc
    15601 aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa tcgcccgaat
    15661 aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc aaataaacac
    15721 cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa aagtgaaaaa
    15781 tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca atcccattac
    15841 cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga agggcatacc
    15901 tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa agaatgtcgt
    15961 tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac cgaaaaactt
    16021 ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa taataaaaaa
    16081 taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt tcattcgctt
    16141 ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt ttagcttatg
    16201 tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat tgctcttgtt
    16261 aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag gacccttatt
    16321 gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag attcgatgat
    16381 tacatctaaa acaaaagaga ctctgaaaaa agcaatcaat gccggtcatc atgtcagtat
    16441 tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag aattaacaac
    16501 accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact gggatggtga
    16561 aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa aaaagcagct
    16621 aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca gttttgattt
    16681 ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc tttctcctaa
    16741 aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt ttgcaggagc
    16801 tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga catggggtgg
    16861 acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag gcgtgcaaga
    16921 gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg acgagcataa
    16981 tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg gtactgacca
    17041 actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg gtttagctgt
    17101 ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa aagaggttgt
    17161 gacaattt
//
LOCUS       DAZKPE010000056        17008 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000056 DAZKPE010000000
VERSION     DAZKPE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.056"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..127)
                     /locus_tag="ACG930_002079"
     CDS             complement(<1..127)
                     /locus_tag="ACG930_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFQ0519235.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(231..542)
                     /locus_tag="ACG930_002080"
     CDS             complement(231..542)
                     /locus_tag="ACG930_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0519236.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(544..741)
                     /locus_tag="ACG930_002081"
     CDS             complement(544..741)
                     /locus_tag="ACG930_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0519237.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1135..2862)
                     /locus_tag="ACG930_002082"
     CDS             complement(1135..2862)
                     /locus_tag="ACG930_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFQ0519238.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2855..4048)
                     /locus_tag="ACG930_002083"
     CDS             complement(2855..4048)
                     /locus_tag="ACG930_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFQ0519239.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4235..4879)
                     /locus_tag="ACG930_002084"
     CDS             complement(4235..4879)
                     /locus_tag="ACG930_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0519240.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4973..5107)
                     /locus_tag="ACG930_002085"
     CDS             complement(4973..5107)
                     /locus_tag="ACG930_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFQ0519241.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="ACG930_002086"
     CDS             complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="ACG930_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFQ0519242.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7238..7711)
                     /locus_tag="ACG930_002087"
     CDS             complement(7238..7711)
                     /locus_tag="ACG930_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFQ0519243.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8112..8336
                     /gene="nrdH"
                     /locus_tag="ACG930_002088"
     CDS             8112..8336
                     /gene="nrdH"
                     /locus_tag="ACG930_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFQ0519244.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8495..10654
                     /gene="nrdE"
                     /locus_tag="ACG930_002089"
     CDS             8495..10654
                     /gene="nrdE"
                     /locus_tag="ACG930_002089"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFQ0519245.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10704..11669
                     /gene="nrdF"
                     /locus_tag="ACG930_002090"
     CDS             10704..11669
                     /gene="nrdF"
                     /locus_tag="ACG930_002090"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFQ0519246.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11758..12897)
                     /locus_tag="ACG930_002091"
     CDS             complement(11758..12897)
                     /locus_tag="ACG930_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFQ0519247.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13206..13919)
                     /locus_tag="ACG930_002092"
     CDS             complement(13206..13919)
                     /locus_tag="ACG930_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFQ0519248.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="ACG930_002093"
     CDS             complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="ACG930_002093"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFQ0519249.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15108..16640
                     /locus_tag="ACG930_002094"
     CDS             15108..16640
                     /locus_tag="ACG930_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFQ0519250.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16831..>17008)
                     /locus_tag="ACG930_002095"
     CDS             complement(16831..>17008)
                     /locus_tag="ACG930_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0519251.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3496 c         2910 g         5323 t
ORIGIN      
        1 atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt gttccagcac
       61 ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt ctattttttt
      121 cttccattac gattccccct acaaactata aatactttta tgtcactgat tcaatatacc
      181 tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca ttaaaattga
      241 gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct tccaatttca
      301 ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt agtataagca
      361 gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa ttcatatttt
      421 tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga
      481 tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc
      541 attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat
      601 acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt
      661 tccataatat tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga
      721 caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt agactattat
      781 tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct
      841 gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga
      901 gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc
      961 tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga
     1021 tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca
     1081 aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt
     1141 tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg
     1201 atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa
     1261 attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt
     1321 atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata
     1381 tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat
     1441 cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt
     1501 caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc
     1561 gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat
     1621 gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac
     1681 ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat
     1741 ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat
     1801 cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc
     1861 tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact
     1921 ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg
     1981 ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg
     2041 ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc
     2101 attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc
     2161 gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc
     2221 catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct
     2281 cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt
     2341 aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc
     2401 gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa
     2461 gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa
     2521 tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat
     2581 caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt
     2641 aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa
     2701 aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct gtccaatcgt
     2761 ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac
     2821 ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg
     2881 tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct
     2941 ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca
     3001 tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct
     3061 tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa
     3121 cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat
     3181 cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg
     3241 aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt
     3301 cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa
     3361 tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt
     3421 gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg
     3481 cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt
     3541 gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat
     3601 tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta
     3661 acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa
     3721 ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat
     3781 cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga
     3841 tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta
     3901 cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt
     3961 tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg
     4021 ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt
     4081 tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga
     4141 aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt
     4201 agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt
     4261 aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc
     4321 ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg
     4381 cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat
     4441 gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc
     4501 gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt
     4561 gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat
     4621 attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc
     4681 gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag
     4741 aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc
     4801 ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga
     4861 tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct catcttacta
     4921 tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct
     4981 tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt
     5041 ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg
     5101 tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt
     5161 ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct
     5221 aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa
     5281 taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc
     5341 cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat
     5401 gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt
     5461 tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg
     5521 accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa
     5581 acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga
     5641 gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt
     5701 cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat
     5761 tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa
     5821 cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca
     5881 gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc
     5941 aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg
     6001 ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata
     6061 ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg
     6121 atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat
     6181 tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc
     6241 tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat
     6301 gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc
     6361 agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt
     6421 gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag
     6481 agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg
     6541 tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact
     6601 gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag
     6661 cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa
     6721 cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc
     6781 ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca
     6841 ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc
     6901 atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa
     6961 agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga
     7021 accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg
     7081 ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact
     7141 gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta
     7201 gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta
     7261 tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt
     7321 cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc
     7381 ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag
     7441 tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat
     7501 tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta
     7561 aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga
     7621 tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga
     7681 aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat
     7741 gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa
     7801 tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg tgatactatg
     7861 agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca
     7921 caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt
     7981 tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt
     8041 ttgacttttt tactaagagt tttatactat ctattataga taataagaat gtgttagagg
     8101 aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg
     8161 tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc
     8221 ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg
     8281 atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg
     8341 actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg
     8401 tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc
     8461 atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt
     8521 cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa
     8581 taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac
     8641 ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga
     8701 attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca
     8761 acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa
     8821 aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct
     8881 ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca
     8941 acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt
     9001 ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa
     9061 ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg
     9121 tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat
     9181 gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg
     9241 cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga
     9301 aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa
     9361 attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga
     9421 aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt
     9481 tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc
     9541 aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga
     9601 gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca
     9661 aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg
     9721 taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt
     9781 gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc
     9841 accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca
     9901 cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa
     9961 tatttacttc atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga
    10021 aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga
    10081 aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg
    10141 catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg
    10201 actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga
    10261 tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat
    10321 cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt attacacttc
    10381 tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt
    10441 cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga
    10501 atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt
    10561 ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat
    10621 cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat
    10681 attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg
    10741 aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag
    10801 atacacgtat cccactttca aatgacctag atgattggcg tacattgtct caattggaaa
    10861 aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa
    10921 gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca
    10981 atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga
    11041 atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa
    11101 aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg
    11161 ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt
    11221 taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat
    11281 ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag
    11341 cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg
    11401 aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat
    11461 tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag
    11521 atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc
    11581 atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag
    11641 acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa
    11701 aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta
    11761 ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct
    11821 tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg
    11881 tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat
    11941 gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc
    12001 atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat
    12061 aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat
    12121 attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat
    12181 tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc
    12241 agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg
    12301 aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat
    12361 aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac
    12421 acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga
    12481 tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa
    12541 ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc
    12601 cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa
    12661 cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg
    12721 atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat
    12781 tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt
    12841 gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca
    12901 tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag
    12961 attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac
    13021 ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa
    13081 taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg
    13141 aactattttt atttggctgg gcttattact tgatgtagga catctatttt acaacctcag
    13201 atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac
    13261 tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata gatatttttg
    13321 tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt
    13381 ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt
    13441 tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca
    13501 atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat
    13561 ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg
    13621 atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct
    13681 tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca
    13741 ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc
    13801 gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat
    13861 agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc
    13921 taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt
    13981 ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa
    14041 acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta
    14101 tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc
    14161 tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc
    14221 gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt
    14281 gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat
    14341 tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg
    14401 tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga
    14461 agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc
    14521 gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc
    14581 ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat
    14641 gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac
    14701 agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg
    14761 tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat
    14821 ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat
    14881 tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat
    14941 tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa tccgtgttag
    15001 gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc aagtgattca
    15061 ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg agtatactga
    15121 cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt gtcgatctgc
    15181 aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt aaaagtacat
    15241 tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat tggcaaaaaa
    15301 atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta acaatcgaag
    15361 aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt
    15421 accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg aaactccaaa
    15481 cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag atgagcagcg
    15541 ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt ggtggacaac
    15601 gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg atcttagatg
    15661 aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt cttcaggatt
    15721 ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag atcaccaccc
    15781 atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta aaacaagcat
    15841 tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct caacaaaaac
    15901 aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga tcaacgatgg
    15961 caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca gcttcagcaa
    16021 gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca gtggaaacaa
    16081 ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg accatccgct
    16141 ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact ttattaaaaa
    16201 cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat aacacaaaaa
    16261 tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca ctacaatatt
    16321 taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta gctaaagcag
    16381 ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg gaacaaacta
    16441 aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc gatgaaccga
    16501 cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag aaatttccag
    16561 gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg caacgagtca
    16621 ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa
    16681 agttttgtca caactccttc ttctgaataa atggtggcca attagctgac cttcggtatt
    16741 agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt attacttgat
    16801 gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat ttctctttcc
    16861 tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc cgctaaccgt
    16921 tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac cagccgcacc
    16981 tccaataaag tacataaaca taaataca
//
LOCUS       DAZKPE010000057        16962 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000057 DAZKPE010000000
VERSION     DAZKPE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.057"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1087
                     /locus_tag="ACG930_002096"
     CDS             <1..1087
                     /locus_tag="ACG930_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0519252.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="ACG930_002097"
     CDS             complement(1305..2447)
                     /locus_tag="ACG930_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0519253.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="ACG930_002098"
     CDS             complement(2452..2637)
                     /locus_tag="ACG930_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0519254.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="ACG930_002099"
     CDS             complement(2991..3236)
                     /locus_tag="ACG930_002099"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519255.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="ACG930_002100"
     CDS             complement(3230..3631)
                     /locus_tag="ACG930_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0519256.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACG930_002101"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACG930_002101"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFQ0519257.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="ACG930_002102"
     CDS             complement(5649..7415)
                     /locus_tag="ACG930_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFQ0519258.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="ACG930_002103"
     CDS             complement(7428..8222)
                     /locus_tag="ACG930_002103"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0519259.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="ACG930_002104"
     CDS             complement(8232..9608)
                     /locus_tag="ACG930_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0519260.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /locus_tag="ACG930_002105"
     CDS             complement(9728..10375)
                     /locus_tag="ACG930_002105"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFQ0519261.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACG930_002106"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACG930_002106"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFQ0519262.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACG930_002107"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACG930_002107"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0519263.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="ACG930_002108"
     CDS             complement(13042..14673)
                     /locus_tag="ACG930_002108"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFQ0519264.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="ACG930_002109"
     CDS             14977..15648
                     /locus_tag="ACG930_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFQ0519265.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(15808..15999)
                     /locus_tag="ACG930_002110"
                     /pseudo
     CDS             complement(15808..15999)
                     /locus_tag="ACG930_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(16367..16708)
                     /locus_tag="ACG930_002111"
     CDS             complement(16367..16708)
                     /locus_tag="ACG930_002111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519266.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
BASE COUNT         5542 a         3272 c         2252 g         5896 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
    16561 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
    16621 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
    16681 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
    16741 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
    16801 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
    16861 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
    16921 tccagttaca tttaattttt aaacaaaatt ctccccaaaa ag
//
LOCUS       DAZKPE010000058        16682 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000058 DAZKPE010000000
VERSION     DAZKPE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.058"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            91..312
                     /gene="relB"
                     /locus_tag="ACG930_002112"
     CDS             91..312
                     /gene="relB"
                     /locus_tag="ACG930_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFQ0519267.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            314..580
                     /locus_tag="ACG930_002113"
     CDS             314..580
                     /locus_tag="ACG930_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0519268.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            747..1232
                     /locus_tag="ACG930_002114"
     CDS             747..1232
                     /locus_tag="ACG930_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519269.1"
                     /translation="MGWYGAYSSANEVIEEKKGYAKNGLEIVDTKVTKTYGIILFKDA
                     EGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFFVGDQEKMVKQQLDRIKEE
                     NNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQDGSLTRFTRLSAGDVKEV
                     A"
     gene            1726..2010
                     /locus_tag="ACG930_002115"
     CDS             1726..2010
                     /locus_tag="ACG930_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519270.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            2284..2538
                     /locus_tag="ACG930_002116"
     CDS             2284..2538
                     /locus_tag="ACG930_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519271.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            2620..2805
                     /locus_tag="ACG930_002117"
     CDS             2620..2805
                     /locus_tag="ACG930_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFQ0519272.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            2872..3267
                     /locus_tag="ACG930_002118"
     CDS             2872..3267
                     /locus_tag="ACG930_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0519273.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEDLLEK"
     gene            3284..3634
                     /locus_tag="ACG930_002119"
     CDS             3284..3634
                     /locus_tag="ACG930_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519274.1"
                     /translation="MKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDLIIFEDNNLR
                     IEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKKAKLLFEFQT
                     DYHNELLAQSEILD"
     gene            3656..4030
                     /locus_tag="ACG930_002120"
     CDS             3656..4030
                     /locus_tag="ACG930_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519275.1"
                     /translation="MKQTQTEPINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
     gene            complement(4336..4734)
                     /locus_tag="ACG930_002121"
     CDS             complement(4336..4734)
                     /locus_tag="ACG930_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0519276.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(4924..5691)
                     /locus_tag="ACG930_002122"
     CDS             complement(4924..5691)
                     /locus_tag="ACG930_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0519277.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(5726..6886)
                     /locus_tag="ACG930_002123"
     CDS             complement(5726..6886)
                     /locus_tag="ACG930_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0519278.1"
                     /translation="MKITEKNVNPKFETTESNLKKFDLTVTLSNQLVDSIVEMDAMPQ
                     KIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSSSSKHSRLKQVIEKLHQQSVIK
                     IQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSSIMPLLTNLEDHFTQYTFDQVV
                     NLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDRLKNPVFSIADLRKKFSIEKKY
                     KAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTYTNIKFLLTRTMSVPVPYKQEQ
                     RDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFLISSADLCDLKLMSRLQNKVYP
                     LYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYLEKSITSYLPYVNLYD"
     gene            7930..8733
                     /locus_tag="ACG930_002124"
     CDS             7930..8733
                     /locus_tag="ACG930_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0519279.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            9318..9773
                     /locus_tag="ACG930_002125"
     CDS             9318..9773
                     /locus_tag="ACG930_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519280.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            9892..10950
                     /locus_tag="ACG930_002126"
     CDS             9892..10950
                     /locus_tag="ACG930_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HFQ0519281.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            10992..12941
                     /locus_tag="ACG930_002127"
     CDS             10992..12941
                     /locus_tag="ACG930_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0519282.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            12944..16585
                     /locus_tag="ACG930_002128"
     CDS             12944..16585
                     /locus_tag="ACG930_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3659 domain-containing protein"
                     /protein_id="HFQ0519283.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
BASE COUNT         5867 a         2568 c         3101 g         5146 t
ORIGIN      
        1 tgtttatgtt tatgtatata ttcatatata taactattgc atttgtcata caatcgtagt
       61 acaatgtaat tgaaaaggag ttgataaact atgccagtaa taagtattcg tgtatctaaa
      121 gaagaaaaag attttcttga aaaagttgct gaattcaacg gagataacat ttctgaattt
      181 atgcgtagta attccctgca aacagcagaa acgttagtag actttgccac ctacaaggaa
      241 ctaatgaaag agcatgagga aaacgatcaa agtatttccc acgaagatat gctaaaagag
      301 ttaggcttat aagatgactt accaagtaag atatgaacgt gaagctcaaa aagcgctaaa
      361 aaaaatggat aagtttcagg caaaggttat cctaaactgg atcgagaaaa atcttgtagg
      421 cactgatgat ccaagaaaac atggtaaagg tctaacagct aataaatcag gctactggcg
      481 atatagggta ggtgcctacc gtataatagc tgatattagc gagcatgaag tgacaattct
      541 tatattgtct attggtcaca gaagtgaagt ttataagtaa cagacaagct gataaggctt
      601 gtctgttttt ttgttaaccc aacaaaatca ctgtttacga tcccacttta cctaaaaaag
      661 aacaataccc tcttgttatt atacacactg gtgtgtataa tataagtgta aacaagctaa
      721 ttaactttca aaaggagcga ttttttatgg gatggtatgg tgcttattca tcagcaaatg
      781 aagtgatcga agaaaagaaa gggtacgcca aaaatggttt ggaaatcgta gataccaaag
      841 taacgaagac ctatggtatt atccttttca aagatgcaga aggaacctac gatattgaca
      901 gcttcatctt tcgagatgaa atgtacaaac caatctactt cttaaatgac agtcctgctt
      961 actttaagaa aattccgaaa aaatggttga aattctttgt cggtgatcaa gaaaaaatgg
     1021 ttaagcaaca actagataga attaaagaag aaaacaataa accaaacctt gatgacttat
     1081 tagttgcagg taaaacttac tcaatctggg atggatcgta tgtcgctgtt tatcagtata
     1141 aactcaaacg tagctttatt tttagactac aagatggatc actcactcgg ttcactcgac
     1201 tatcagcagg agatgttaag gaagtagcct aaaacttaaa tacataaaca taaacgtgta
     1261 tacgtttatg tttatgttta tgtatatgta tatgaatata aacgtattag gtacgaacgt
     1321 ttttaaatgc ttttctgggc tttgatttta gggtagggct aaaacatcca ttgatccaaa
     1381 acagctcaga aacgcattta aacgtatctg ataccaatat tacagaagga gtgtatcgta
     1441 tgattaacct atttctttta gtgacagcta gtacattatt ctttactgga atatcactga
     1501 taatttccta tttgatctat aagaaagccg aaacttacac aagcaaagca accggactag
     1561 ccgtttcctc ctttttaact ttgctgactt tttttgttac tctatcgttt tcttttgttt
     1621 agcacagctg atccatcagc aaaaaacctc tctttacatt atacacacta gtgtgtataa
     1681 tgtaattgta aacaagctaa ttaactttta ggaaggagtg acaatatgct aacagctaca
     1741 ttacagcaac ctactcacgt tgctattgca gaaagctata caattaatgc aggggtcgtt
     1801 aaacagctga tcaaggatcg agaattcaaa aagtttaaca gtcgtcaagc gtataacaga
     1861 cagttaaaga aagctattct aaagcacaaa aattccttca tagggaaatt ggaaagtgtg
     1921 gatgttaaaa ctgtttcaac ggcattttca gttgttgaag tgactattga cggtcgcttg
     1981 atttctctat ttgcttttgg aattaattga tagggagtgt ggactttgga aggtaagact
     2041 tttgcagaaa tttggactga atttattgag gtaccaactc gcattgatcc gataacttct
     2101 gaaaaggtat tggatgcaga cttctacaat ctcaaagcag gtactagcct tgaatgcgtt
     2161 tagatgtatt tagaagagca tttcaaaggc gtaacgctcg gtcacgtctt ataccacaat
     2221 ggtgccgagt gggatgcaat tggaaatatc catttttctt aatacaagaa aggagaacac
     2281 aatatgaatt ataccgatga agaacaaatc actttggaat acgttttcac aaatgaaaaa
     2341 ggggaggaaa ttgaaaaagt cttgatcatt tcatcaaaag acttggagaa cgctttgact
     2401 tatgaaccat acgaatcaac cgtaactgtc aatgaattct tagataccta tacttctaat
     2461 gatacttggg aaattatgaa tatttgcaac gctaataaca ttcaatttgc tgaaaaaacc
     2521 aataaatcat tttattagtt ttgcaataaa acatcctctt tttctattga ttccatacac
     2581 aacaatgtgt ataatagatt ttgtaaaggg agggtagcta tgcctaagac agcaagagaa
     2641 attgtaaaaa ttctcaaatc taacggcttc aaaaagactg gacaaactgg cagtcatgca
     2701 aaattttata attccaagac taaaagaacg gtcgttgttc cgatccacaa tggtgatgta
     2761 ccactaggaa cagaagctaa tatctggaag caagcagggc tttaacagcc ttgccttcct
     2821 atttggtatt aggcatacta tcctctctta cactagaaaa ggagcgagga aatgaagaca
     2881 aaaaatattt tttatccggc aatcttcgag aaagaaggag aagcttataa catcgttttc
     2941 cctgacttac cggaaatatc tacctttgga aatagtcttg aagaagcata tttaaacgct
     3001 aaggatgctt taggattagc gctatatagt gtaccagatg cagaatttcc taaaccatca
     3061 gcagtggaag aattaacttt gaaagccaat caagtagtag taatcatcca actaaacatt
     3121 aaacttttcc gaagaagctt aaatacaaaa acaattagaa aaaatgttag tgttccggaa
     3181 tggttagttc ttttagggaa ggagaaaaac ataaacttct ctcaattact tcaaaaagca
     3241 ctagaagaag acttgcttga aaagtaaaaa ggagaccgaa cctatgaaat ctacacactt
     3301 aaactatttc tctcgaacgt taatcaataa tctattaaaa gatacaactg gcattagcgt
     3361 tagtaccaaa cactttgcca atgatctaat tatttttgag gataataact tgcgaattga
     3421 gatgtttatt gaacaggcaa ctcctaactc aatacctgaa ttctgctata cgcacactga
     3481 aaaaatgaaa catgcaaaat cagttaaaga tgttgaagca ttaagtgaat cactaacgaa
     3541 cgctttaaac ctcgttaaga aggctaaatt gttatttgaa tttcaaaccg actaccacaa
     3601 tgagttgctt gctcaatctg aaattttaga ttaattgaaa caggagaaga gaaagatgaa
     3661 acaaacacaa acagaaccca ttaacgatac gcttgctgat caattagcag gttattataa
     3721 attatttgag atgagtaaag cacagcgctt gatccactat ctttggaaat acaaaatttt
     3781 gtttcttttt tgggaagcaa cactaacatt ctcagttctt ttttataagt cagattttta
     3841 taatcaacac ttagttttag ggagtttttt gcttatctac accattttga tgcttaattt
     3901 atatacctac atcacacttg aagaacactt agtaattagc gatgcaggga tcgagagaaa
     3961 catcaaaagg gtatctttca agatcacgtt aaacaagcct accgataaaa agctctcaga
     4021 agcgttctga gagcttttga cattttcttg tataatttat cctaacacat tacaaagcac
     4081 ctaattcgag cttatatcaa gcaaatttgc tatttattcc tcaatacata tctaaaaatt
     4141 acttgatgga aaactagata catggtaagc atgaaaagaa aatcaatttg agcagatgca
     4201 gtataataca tagcaattta aaagctctca gaacgcttct gagagctttt aatatattct
     4261 ttgataattt gtctttctta aatccatacg tcctaaaaca agctgttttt gcttaatatg
     4321 atcatctgag agacatcaaa tcaacttttc tctcaacaaa tcattcaaag ctttcgacag
     4381 attaatattc tcttcagccg ctaaaacatt taaatagtgt tccacagtca ctgattttcg
     4441 atcataattt tgcttgtttc gagctttagc aactttcgta ttagctttta cgacaaataa
     4501 attaacattc tcagatcgct tgattcttgc atttaactct tgaacaggcg taggcgatgg
     4561 aatttctttt tcttgcaact ctaaaagcac caagtatcct tccaatactt cttgcgccat
     4621 ctcaaaagca tcttctaaag tttcaccatg cgtatataag tctggaaaat ctgggaattt
     4681 aactgcatat tcatttcctt tccattcgaa tactgcacaa aaaaagtatt tcatcgcatt
     4741 gcacctctct aattaaaaaa taatttttgc tttttggttt caaaaaaaga atcgcctacc
     4801 aaaaaattga taggcgatca caagctaatt aacctctaaa ggagattaat accttgctcc
     4861 caaggcacta catatcttaa catacgtctg aagcatcttc aaacgagtaa gatatatttt
     4921 gcattaacct aatttttttt ctctataagg tttttcatca aactcactag aaatattaaa
     4981 ctggacagca aaattgtaat ttctgccttt tctaacttta gcaaaatcaa tcttcagcat
     5041 tgatttttca ttaatttctt caactgattc ccttaaaaca cgtctatcaa aattcgatat
     5101 tgttttatac tcattttctg ttttcgtaat ctcacgaatt ttaactattt caatcagggg
     5161 attcttatat atttcagctt tctcaaaatc tcctttattt ttggcgataa gatatttttt
     5221 ataatacatc gccaaatatt tgtataacac gatgctatat tttttttgaa aagatgctaa
     5281 gtctttaaaa acaaagaacg gatacttctt tttgattgag acaattaagg gaattacatc
     5341 ttctgaaaaa ctgaaagata cactatgctc ttctaaatcc caatgaatcc gatcaatagc
     5401 agatacagta gtatacgtct tatatttctt gtctagattc gatatttcat aaactgcttg
     5461 tctttgcaaa gtgttaacta tggtttttag ttccgtttca agattttgat caacatccat
     5521 gtaattaata atcgctttaa caggtaaatc tactacgcct gttttcttta gctttgtggg
     5581 tgagatataa ctgaacagca attgataaag ttcatacgac tttaaatcca ttttcatatc
     5641 aattgttgct aagaactcct cattgtactt tgtcagttca tcttttttca aaagtttttc
     5701 cttccttcac gcattttttc agttgttaat cataaaggtt cacataaggc aaataactcg
     5761 taattgattt ttcgagatat ttaacagtat tttttattgt gtaatcctcc ttatgagtag
     5821 caacgtaaga taggtgattg acaactgatt caaatcctct atctttggat aaacgatcat
     5881 aaagcggata aactttattc tgaagtcggc tcataagttt aagatcgcat aagtcggcag
     5941 aactgatcaa aaagtttttg attagtaatt tagtgtattt gctattcata gctttcaagt
     6001 acgattgatt cattttctct gttttatctt ctgcgccttt taaataagca gggtctcttt
     6061 gttcttgctt ataaggtacc ggaactgaca tggtacgtgt aagcaagaac tttatgtttg
     6121 tataagtatg acccttcttg ataagctcat agtcaatttt aaaatcagtg tatttattca
     6181 gttgggcaat cggttcttta attacacgtc tttcaaagtc tcgaaaagct ttatattttt
     6241 tctcaatact aaatttcttt cgtaaatctg caatggagaa aacaggattt tttaatctat
     6301 caagtgattt tgtactccat gttaagttat ctctatttgc ttcatacaga ttaaaatctt
     6361 tagtgaataa ttgaaaaaaa ctgatcgcat acttgcttgt caagttaact acttgatcaa
     6421 atgtatattg cgtaaaatga tcttctaagt tcgttaataa aggcataatt gaactactaa
     6481 atttaataga tactgcatca gaaaaatcat tgaattcagt aatttctagc ggtgagatga
     6541 ctttgtattc agtcttaccg ttaggtttag ttctttgaat tttaatgaca gattgctgat
     6601 gcaatttttc aataacttgt tttaatcttg aatgttttga agaagatgaa ctagaagaca
     6661 tcaacgcaaa taaagccttt ttagatactt tgacggtatt attaaaaggc ggatttttag
     6721 ggtcaagatg tcctatagcg taaagataaa ttttttgtgg catagcatcc atttcaacaa
     6781 tgctatctac aagttgattc gataaagtaa cagttaaatc aaactttttt agattgcttt
     6841 cggtagtttc aaatttcggg tttacattct tttctgttat tttcatacga ttgcctcttc
     6901 tttctaagct tggtacgagc ttaaaaactt ggaactggta cgattccatt gaataagtat
     6961 agacctgttt tcgatacgtt acaataagaa atgtatcgta aatttataac ataactcaat
     7021 gtcagtaaaa cacattttat tttttccaat caaatttcat tgaaaataca gcagaaatcg
     7081 ctattttaga acattttcaa aataaaaatc cttttcaata aaatacgaaa ttataaaaat
     7141 taccaaaatt aaaaaacaaa tatttttcta gtttttagaa ataaattcac atactttttc
     7201 tttttttgga tatattcgga ataccacatc gctttttgtc cacgtttgca tcgctttttg
     7261 tccacattca catcgctttt tgtccatgtt cgcatcgctt tatgtccacc ctaaaatcta
     7321 tttaagattg atataaagcc tttttggagg ttgctaaagt tttaaagatt aaaatatata
     7381 ttataaatat aaataaaagg ggaagctgaa gcttcctcct tttccttttt ttcaattatt
     7441 caaagttaca caagcaaaat aaactcctag atagtgttag ttttttttaa gattttttat
     7501 ttttaagatt ttgaaataag agaggagtaa tcctccttta ttaaatatct gttaatatat
     7561 ctgttaaata tctgttaata tatctgttag gggaggctta atctcttggg agagtaagta
     7621 ttaaaggggt ataaaggtaa cacttttgga cagtaaaggt aacaaaagtg gacagtaagg
     7681 gtaacagttt tggacagcaa aggtaacaaa agtggacatt tgaggtatca cactaggata
     7741 agacgttacc ttcggttttc ttgatttgga aggcgaaaaa atagaaaatt agattagtaa
     7801 caaatctttg ttgactgtta cctttagttg tgatttaatt taggtaacaa gcagaaaaaa
     7861 ttgtttcctt taattagtac cagattaaca tgattaaagg agcgcaaaaa gaagattgga
     7921 gagtaatcaa tgtctcaaga agttaccgaa aagattattg atagtgatgt agatttagta
     7981 tcagaacaaa caaatgcaat tgtgcgttat aacaatggtc tgaatacaac agctttgcga
     8041 ggatttaagc ctgttgaaat ggatgtgttt tgggctattt tatcaaaaat gaaacgtcaa
     8101 ggaacagcag aagtaacttt tgatttcaac ctctttcgtt atttggtcaa atacgacaga
     8161 agagaaaagg acagttttta ttctgtgtta aaagatttga gtgacaaact aggtaattta
     8221 acctaccgtt ttgaagattc agacgtctat gaacagctgt ggctttttca aaaattccgg
     8281 atagataaac agaaggaaac agttacaatt aaggcaaatg aggaatttga atttatctta
     8341 aactcaattg gcaaaaactt tactcgtttt gaacttgata attttacaaa actaagaagt
     8401 agctacacaa aagaattgta tcgtcatctc atgcaataca gaaataaaga gtggcgaaat
     8461 ggttattggg tagtcaaagt tgaagatttt agaagagcat taagtatacc ttcaagttat
     8521 agaatgacaa atattgataa aagaatacta gagcaggcga aagaagaatt tttagctcct
     8581 gatgaaaacg gaatacaggt atttgaaact tttgattatg aaaaaatcta tgcaaagaaa
     8641 ggaagaagag ttgatcggct cagattcact tttagtgagc cagaatcaaa cttgccaacc
     8701 atttcaatgc ataattggtt agaagaagat tgagaagaag caggttgtaa ttttaataca
     8761 acctgcttct ttaaaaaagt atgggtaaca cttttggaca ataaatgcaa gaagtttttt
     8821 tgtaagcaag tttcagtcta aataatattt gaaagaatgg ctaatctata caaattttaa
     8881 caactatggg taacactttt ggacaagtca agaaaaaaaa caatttttct taatttgttg
     8941 atcgactaaa ggtaacactt ttggacaaca cagaataaaa agtccggtga tatcagtttt
     9001 ggtaggaaac atcttaatat ctttgtgaga ttgaaggtaa catttttgga caagtcaact
     9061 atttgttaaa agttaatata gagtaattag ataagttttt tcttttcgtc tgataaatgg
     9121 ataatattag ttattttatt gctaattagt ctttcatgat gactgaaata gctaaaataa
     9181 atatctcgtt ggataattgc tgatacttta agggatatct aaatttgctg attgatttat
     9241 ttatgttatt atgatattat aataacataa atgtgttacg cccgaacctc attttaaaaa
     9301 aatgaagggg tgagacaatg aatgctatta attggcatga atttgttaac tatatggaga
     9361 gcttactaga tgatctaaaa agttttagta ttgctgatgc agtaaagcat gggttaccag
     9421 ttagtacaac gatgaaatta cgaggattga aaattccaga tgaaattatt aagctgagaa
     9481 ctaaaacaat tattgaaacc gcaaaagtcg ttgacaatat gaaccatgaa ctaaaaggca
     9541 agaaaacaac ttacgagaaa gattttgaac gttttttaaa atctgttatt ggaaaatatc
     9601 taggtaaaaa atctttcagt gaattgagag atgaagagat tgtacctact ccaatggtta
     9661 gcaaaatccg aaaaaacaaa gccgagggga attactatct tggtacaata gcaaaaatca
     9721 ttgattattt ggaaaataaa gagcaaaaga aaggaacgaa gaaaggaaga taatttttgt
     9781 gttaaatatt aatggggaag aatataccga aatgattcaa aatcccgaac ctagaattac
     9841 cgaaaaaacg tctgattgtt tgctctttta tgaaaggggg cagacaaact aatggaaaaa
     9901 aacgtcaatt caacatctac caaagatcaa tacagtatta ttggagggtt gcttggtgat
     9961 aaggataaga gaacacgtca cggattacgc attatgcttg caacttttct aggagtgctt
    10021 tttttattaa caggcttggg tagctacatt tatcaattag gaaactataa ttattatctc
    10081 gtgaacaata caacacctat aggctcttca ttggagtttg ctcgatcagg agcagagatc
    10141 actatttcag atgtgtggac agatcaaaac agagatgtaa cagtagtaaa actcggttac
    10201 tcgcaaaacg ctagaaagtt gttatctacg caaggaaaaa actacaactt atatatggca
    10261 acgaaagaaa aagatcgtcc taaaaagctt gaaatgagct atgggatgtt aagtactgat
    10321 ggggatgctt tcttattcct aaaaggtaaa ttagatgaaa gagcttatca agtttttatt
    10381 gcaaaccaag tatcactaat ttctggtgat gatacagctg acgatgatac caaagtcaat
    10441 gtgaatgaag cagattcagt tacaaaagca ctttctcaat attctatgaa tgatgttaat
    10501 aatgaaggag taatttcttt tgggaaaaaa gcaaaacctg ttaatactcc tgataatatc
    10561 aatttcagaa taaatccata ttcagattca actaatgtct atcaaggaag ctttcttacc
    10621 aaagatggcg atattgatta ttcaaaagtt gtagcagtta caagtaagaa taatgttgta
    10681 agtaagttag aagatcagtt aaatgcttca aatactaaca tcaagaaaat tgaagctaca
    10741 aaagctgagt atctggaacg tttacaacaa aatcctgacg ataaagattc gcaagaaagt
    10801 attcgtcaac tagacagtcg aatggagacc gaaattaaag caatcaatga tacacaaaaa
    10861 ttgattgatc aatacaaaaa tgctgacttt aacaaagatt cttttggaga catgaagacg
    10921 acatttaagt acctaactct gactgactag aagtaaatta ttcttatttt agaggaagtg
    10981 aacacaaaca gatggaaaat agtaccgagt tttttaagaa tattcaaact gaatttaatc
    11041 atgctctcac accaatgaaa ccaccgaaac ataagttagt gggacgtgat gacgaactcc
    11101 atgagttgtc actgatcttg aatagaccgg aaacaccgca agctatcttg ttaggtgaag
    11161 ccggaacagg taaaacagca cttgcaagtg aatgggctga aagacagcga caagatggaa
    11221 agaaagtaca agtatacaaa ttatcaatcg gacaattgcg tgttggggga gatgatgtcc
    11281 tccaaacacg tttagaaaca ttaattccaa gattgaaaga atatgagcga attttaaaat
    11341 ctgaggacaa agaaaatgaa tttgtcctct tcattgacga gtttcataaa gttgttagct
    11401 cttttggtag tggcaataaa attgggggtg attcgctaaa agaaccgtta gcaaatgaat
    11461 cacttcaatt gattaccgct actacaagaa aagaatatga aaactatatc aaaagagatg
    11521 atgccttagg gagacggtta caaccgttag aattgaatga actaaaaagc gatgttgtcg
    11581 tcgatatttt gagacaatgg ctaaatacat cctctgttaa agatgatcct caggcttctt
    11641 ttaaattatc gcaaaggatt cctgatgaat tacttcaaga aatcgtacaa gcaaacaagc
    11701 tttatcgtga ggatttgtcc gaaccggcta aatcaattgc cgtaatggag gatttgattg
    11761 caaaagatcg agtagacgga aatgcttata atcgagaaag tctattgcaa atatttggta
    11821 agtataatat tcagctagat tctgattttg atatggaaaa acttcaagag gaattaaagt
    11881 ccataaaagg gcaaccgtta gcagtttata ctataacaat gttgtttaaa cgtatgaagc
    11941 ttggatttga tcgttttaaa ggtcgaaagc aaccaaaagc aactgctctg tttacaggat
    12001 caacaggggt cggtaaaact gcaatggcta aagccgtggc aagaggactt tatggcgatg
    12061 aaaataaagt tctcttagtt aatatgccgg actacaaaac aaaagatgat gcaatgcgtt
    12121 ttagacgact cataggtact catgtaaggc atgatccttc tgcgattatt gtgtgtgatg
    12181 aatatgagaa agctggtgta gaaacactcg atgccttttt atcaatttta gatgaaggta
    12241 ggataagttt tactgaaaga ggatgggatg atcgagaagt tcacgacact gtttcattgt
    12301 caaatacaat tttatttgcg acaacaaatg caggtgcgga gatgttcgat tcgttaaaca
    12361 gatatagctc actatctcgt gttacaaaca aggaaaattc taatgaatat agcactgaac
    12421 taaaaagaga ataccgaaaa gtcgcatcag ggatcaaaca agccttgatt ggtgaaggtc
    12481 taaagcctga agttattaac cgatttggac gaatagttcc attttgggct ttatccgaac
    12541 aaactcttct ggaaattgct tataatgaaa tgttgaagag tgctgaatta gtacgaaaac
    12601 atttaaatat agatttacgt cttccaccta ggaaagaaag agtatatggt caaaattttt
    12661 atgcagacga tctctccatg cacttagttt ttgacatggc ttcacaagag gattctaaat
    12721 cagggggtgc aaggaatatc ttgcatttag ttgaatctga gtttgaagaa gcgattactg
    12781 aagcaataat tacttatcca aacgcaaaaa tattcgatgt taagttgagt gaagccggag
    12841 cgtttgaagg aaaaggtgat tctaatgctg aaattattgc aaagccttcc gttgctgaaa
    12901 gtaaagaaaa caagattgta ttttcgattg gaggggcgta gctatgaaat tcaagaaata
    12961 tttactacaa aaccttagaa taaaacgatg ggtcgtaaga ggtctagtta ttggaggagt
    13021 attagcagtt actttaggcg ctccttttgg aatgaatgat ccaactcctg acaatcaaga
    13081 tagcaaacaa gaaacagtta taaataagaa cgttgcatat gcggaaagta aaccggcaga
    13141 acaaggaatg tggacactat atgctcgtat cctaatggga gataaagaag ttaatgatag
    13201 tgccgctaaa actggacaaa tgaatttgtt aggacaaggt ggtatcagtg ccgatttccc
    13261 ttattctgac atttctaaac aaggtaattc gattgcaggg ggtaatgcag gtactcaact
    13321 agcatctact ttagcaactt atagttacta cggatatatt gaaacagtct caggaaatgc
    13381 tattgccagt caagcatcat ccattctagg aagtattggt aggacgattg gtagttttat
    13441 cggatcaatt agtttaatcc tttctaatat tgctgaatcc ataaatgaac tccttggaaa
    13501 atttttcatg agtatgaata tattttctct tatggggtgg ggagaaggtg gatcggatgt
    13561 atctaatccg gtatctaaag cattaactag cttgcttaac aatttgggat taaataatga
    13621 attatttaaa gcgatagcaa gcttatctat gctctttttc acagcaatac taggttatca
    13681 aggaatgaaa ttattgtcga aagatggtgt taactcgaag ggattatcac cagtacttga
    13741 aaaatggatt gttcgtattt ttgtattgtt tatattctta ccagtggcag gatcgctatt
    13801 gggagtttat atcaacggca tccagtcagc aaaaaaagat ggagatatac caacaaatgt
    13861 tgtttctgac tacatcatta acacaagact ttgggcttct actcaaaatc ttgctccatc
    13921 atctgatact ggtggtgatg tacctgacgg aaagcctaca tccgaaatca agttcgttga
    13981 tacagattat gaaccatcta aaaaatctgc aatgataaga gcgatcaata ctagcagtta
    14041 tgccagacaa aataatgatc tagattctaa ttcagtcggt atggctctat taaaagaatg
    14101 gtcatcgaat gatactttca atattaatac ttatgccggt gatgttaatg tcgccgaaaa
    14161 tgatgcttat atgggaagag cgcctgctgt ttggacaggc tataatttag gggatggaaa
    14221 agaaggaagt gcaattaaga aaccaaccaa tttaaatgga tatatttggt cagcaaatca
    14281 aaatgtgaca gacgacaatc gcaagcctga tggaaaagga acagcgcata actttgatgc
    14341 tactcaacct tggggcgttg ctaacaatgc aacttttagc acacagtcgg tagctttatt
    14401 gctccaatcg gcacttgata catcgggagc taagttttat gcgtataata tcgctccttc
    14461 aggaattcaa ggcagtgcta agaatatgtc aacagtaaaa acagaatggc gtacagcatc
    14521 cttagttggt catggagcta tgggtaagtt tggctcgtgg ctagcgatga acgctgaatc
    14581 aatcgtttta gcagttcttt acttagcatg tgcttgggcg atgttcaatg tgaatatcgt
    14641 gaaagcattt aaacgtgaat ttattcggat ttgggaagta gttctaacag gatcacttgc
    14701 atcaggagca ggtgtgatgg caatttcatt aggtgttgtt acaacatctc tgatcggact
    14761 acaattacct atctttctga ttacttttat tcgtgcattt ggtgatactg ctgtgggatt
    14821 cattcctaat acattagttg gcgatggcgt agcaaatatt gttcgatctg ctatgatttt
    14881 aggtgtagga tatcttttag tctttaaaaa aggcgaaaaa gtaaataatt tgattaatat
    14941 gcttattggc ttaccacttg aagtagcgtt tgggtttgat gaacgtgcta agttattatt
    15001 tggtaataga aatgatgctg tgcgagttgt ggacggcgtt tctaaagcaa tcaagaaaag
    15061 ccaaggagct aaaaatccct attatgatgg tggcaacagc tcagtaaaag atatggttgc
    15121 aggaggtctt ggagcagttg gagcgcaaaa aatggctgaa cgtttgaaca atatgggaga
    15181 tagcaatgct gatgctaagt ccattgctga taaagtaatt cctgaaacac cagaaggaat
    15241 gtcattcaac ggtggcggag ttggttccac aatcaataat acctctttca aagatttagt
    15301 tcgtcaagat caactacgta ataactccca acaatatatt gatcatttag gacgtatggt
    15361 tgatgaaaac ggaaactttg tcgatgaaaa tggtgaaata ttaaaagata gtaaatacgg
    15421 taaagatgct aaaggcaact ttattgacga aaaagggcgt ttggtcgatg aagatggaaa
    15481 ccttatagat actaatggta aaccattgga agatagtgaa gatggtaata ttggtatgga
    15541 tagcgaagga cgtttaattg atgaaaaagg tcgcttagtc gatgaagatg gaaatcttgt
    15601 tgacgaaaat ggacgcaggt tgctaaatgg tgattttggt catgatagta acggacgttt
    15661 agttgacgaa aaaggtcgtt tagttgatga agatggaaat cttgttgatg agtttggtaa
    15721 taaacttggt aaacacagcg atggatataa tgtgaatgga gatttagtcg atgaggatgg
    15781 gaatatcatt gagacgagag atgcgcttgt ggcagatcga aatagagaac tcgaacaaca
    15841 acggcatacg ccaattgctg ttgcaattcc tgagaatgaa gaagacgaga ttactttaga
    15901 tcaaactcat caagaactga ggaatgaaat gagtggtgag gacgtgtcag acagagtgca
    15961 tcgagaatta ggagatggag catctggtga aagtcagtca agagagctta acagcaactt
    16021 tgataatagt gctattcgga atgacacagt acttaaagac agagaatcgc taacaaaaga
    16081 aacggataaa gaacaatcag atgtgaagaa aaagttcatt cctactccta atgttaatca
    16141 aacagataaa tatgaaacaa atattggatc aggaatgtcg aaagacaatc aatcaattag
    16201 agaacctgaa ctgacaaata aaaataatag aacaaataat tctaaatcta cttcagataa
    16261 ttcagggaaa tctaatcaat caaccaagaa aacatcaaca gctaaatcag ccgttgaata
    16321 tctatcaaaa actggtaaaa atgtttacac ctcagcagat aaagctttag caaaagctcc
    16381 aaaaggtagt ctagcaggga taacctatga agctaaaaac gaagctatta aaataggtaa
    16441 aggaacggct aaggttgcca aggctactgc tacaggagca tccaaaactg gtaaagtagt
    16501 gaagaaatct accatgtcag tcaaggacta tattgtaaaa tacggtaatc aaaaatcaac
    16561 tgaaaataag tctgaagacg agtaaaaaga aggagcattg atttgctcct tctttttact
    16621 ttgatttcta actgaagatg tcaaggaaaa tttctattta tgcaaaaaaa ttattttaaa
    16681 tt
//
LOCUS       DAZKPE010000059        16392 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000059 DAZKPE010000000
VERSION     DAZKPE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.059"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(296..1024)
                     /locus_tag="ACG930_002129"
     CDS             complement(296..1024)
                     /locus_tag="ACG930_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519284.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="ACG930_002130"
     CDS             complement(1002..2576)
                     /locus_tag="ACG930_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFQ0519285.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDLQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="ACG930_002131"
     CDS             2805..3743
                     /locus_tag="ACG930_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519286.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSAVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="ACG930_002132"
     CDS             3755..4666
                     /locus_tag="ACG930_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0519287.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="ACG930_002133"
     CDS             4690..6162
                     /locus_tag="ACG930_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFQ0519288.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="ACG930_002134"
     CDS             6213..6824
                     /locus_tag="ACG930_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0519289.1"
                     /translation="MNENKWIKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFQILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="ACG930_002135"
     CDS             6854..8767
                     /locus_tag="ACG930_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HFQ0519290.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLVLMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="ACG930_002136"
     CDS             8895..11876
                     /locus_tag="ACG930_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFQ0519291.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGNGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="ACG930_002137"
     CDS             11873..13534
                     /locus_tag="ACG930_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-GlcNAcase"
                     /protein_id="HFQ0519292.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="ACG930_002138"
     CDS             13574..14506
                     /locus_tag="ACG930_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFQ0519293.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(14865..16391)
                     /gene="guaA"
                     /locus_tag="ACG930_002139"
     CDS             complement(14865..16391)
                     /gene="guaA"
                     /locus_tag="ACG930_002139"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFQ0519294.1"
                     /translation="MVLDYGSQYNQLITRRIREFGVFSELMSHRITAEEVKAMNPKGI
                     ILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAE
                     LEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYG
                     IQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLS
                     GGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKER
                     FLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTET
                     AQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLG
                     IRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYD
                     YTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE
                     "
BASE COUNT         5235 a         2689 c         3303 g         5165 t
ORIGIN      
        1 atttaaataa ctacatccat ctattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggagatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcagc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg atcaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccaaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tctgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agtgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaaacgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa
    14821 aacgttgatt tatcggcatt ccccatccat attatattta cgtcttattc ccactccact
    14881 gttgcaggtg gtttgctggt aatatcatac acgatacggt taacgtgtgc gacttcattt
    14941 acgatacgga cactgatttt ttgcaagact tcccaaggga tacgggcaaa gtcagcggtc
    15001 atgccgtcaa tagaagtgac agcacggata cctacagtgt agtcatacgt acggccatct
    15061 cccataaccc caacagagcg aatgcctggt aggacggtga agtattgcca gatgtcgcga
    15121 tctaaaccgg cattggcgat ttcttcgcgc aagatagcgt ctgattcacg gacgatttct
    15181 aatttttctt ctgtcaattc accaaggaca cgaataccta agcctggtcc agggaatggt
    15241 tggcgccaaa cgatgctgtc aggcatgcct aattgggtac ctaattcacg tacttcgtct
    15301 ttgaacaatg tgttcaatgg ctcgatcagc ttgaattgca tgtcttcagg taatccacct
    15361 acattgtgat gtgatttgat ggtttgggca gtttcagttc ctgattcgat cacatcggta
    15421 taaagggttc cttgtgcaag gaaagaaacg ccttcttcac cggcaagttt ggttgcttca
    15481 tcatcgaaga catatacaaa ttcatttcca atgattttac gtttttcttc tggatcagac
    15541 acgccagcaa gttttgataa gaaacgttct ttggcatcga cttttataat gttcaagcca
    15601 aattttccgc caagactttc cataacttgt tctgcttcac ctttacgcaa caatacgtga
    15661 tcaacgaaga tacatgttaa ttgatcgccg atcgcttttt gtaaaagaac accaacaaca
    15721 gaggaatcta ctccgcctga aaggcctaat aaaacttttt tgtcaccgac ttgttcacga
    15781 atttttgcga tctccatgtc gatgaagtta tccattgtcc agtcaccagt acattggcag
    15841 acatctagtg taaaatggcg caacaagtca tttccatatt cggaatggcg aacttctgca
    15901 tggaattgga ttccgtacat tttgcgttct gcattttgga tcgatgcgat ggggcaatct
    15961 ttgctggtag caacgacatc gaaatcagtc ggtgcttggg taactaggtc accatgactc
    16021 atccaaacgg tttgtttttc aggagtgttt tggaaaaggg ccgcttctgc agaagtgatt
    16081 tccaattctg cttttccgta ttcacggttt ttggctggtt taacttttcc gcctaattta
    16141 taagtaatca actgcatacc gtaacagatt cctaaaactg ggatccccaa atcaaaaatc
    16201 ttttcatcaa taccaaaggc cttctcatca taaacactgt ttggtccgcc agaaaggatg
    16261 attcctttag ggttcattgc ctttacttct tctgcggtaa tgcggtggct catcaactct
    16321 gagaaaacac cgaactcacg aatacggcga gtgatcagtt ggttatactg actaccgtaa
    16381 tcaagtacga ta
//
LOCUS       DAZKPE010000060        16373 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000060 DAZKPE010000000
VERSION     DAZKPE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.060"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..2604
                     /locus_tag="ACG930_002140"
     CDS             133..2604
                     /locus_tag="ACG930_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0519295.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2707..4443)
                     /locus_tag="ACG930_002141"
     CDS             complement(2707..4443)
                     /locus_tag="ACG930_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0519296.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4440..5144)
                     /locus_tag="ACG930_002142"
     CDS             complement(4440..5144)
                     /locus_tag="ACG930_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0519297.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5275..5778
                     /locus_tag="ACG930_002143"
     CDS             5275..5778
                     /locus_tag="ACG930_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFQ0519298.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5738..6076
                     /locus_tag="ACG930_002144"
     CDS             5738..6076
                     /locus_tag="ACG930_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFQ0519299.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6097..7515
                     /gene="ffh"
                     /locus_tag="ACG930_002145"
     CDS             6097..7515
                     /gene="ffh"
                     /locus_tag="ACG930_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFQ0519300.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7627..8205
                     /locus_tag="ACG930_002146"
     CDS             7627..8205
                     /locus_tag="ACG930_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFQ0519301.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8209..8730
                     /locus_tag="ACG930_002147"
     CDS             8209..8730
                     /locus_tag="ACG930_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFQ0519302.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8809..9363)
                     /locus_tag="ACG930_002148"
     CDS             complement(8809..9363)
                     /locus_tag="ACG930_002148"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFQ0519303.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9616..9891
                     /gene="rpsP"
                     /locus_tag="ACG930_002149"
     CDS             9616..9891
                     /gene="rpsP"
                     /locus_tag="ACG930_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFQ0519304.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9903..10154
                     /locus_tag="ACG930_002150"
     CDS             9903..10154
                     /locus_tag="ACG930_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFQ0519305.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10279..11070
                     /locus_tag="ACG930_002151"
     CDS             10279..11070
                     /locus_tag="ACG930_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519306.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11240..11761
                     /gene="rimM"
                     /locus_tag="ACG930_002152"
     CDS             11240..11761
                     /gene="rimM"
                     /locus_tag="ACG930_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFQ0519307.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11751..12512
                     /gene="trmD"
                     /locus_tag="ACG930_002153"
     CDS             11751..12512
                     /gene="trmD"
                     /locus_tag="ACG930_002153"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFQ0519308.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12648..12995
                     /gene="rplS"
                     /locus_tag="ACG930_002154"
     CDS             12648..12995
                     /gene="rplS"
                     /locus_tag="ACG930_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFQ0519309.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13127..14263)
                     /locus_tag="ACG930_002155"
     CDS             complement(13127..14263)
                     /locus_tag="ACG930_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0519310.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVNFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(14379..15293)
                     /locus_tag="ACG930_002156"
     CDS             complement(14379..15293)
                     /locus_tag="ACG930_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFQ0519311.1"
                     /translation="MKKIVFGLLFLGLVLSGCSTSPNSASTKENTVSSTSEYETKKLT
                     SSDVHKIKVGDDLTQVYQTLGSPLRKWTNDFVYKELDNAITRDELIVSISKDAQGDYY
                     KEHSELIEHGNSAKDIKKLEMLQYTYSTDSDDETMLIWVSPKTEQVVYYNQRTFLDKD
                     GKSKDSSSTTTTTTTSSSEPQTASVAHSIGEAVPFTSENGNSINVTVQSVSKDYGDDF
                     YKPEGLFYAKVDFLVENTGTTPFDASSSYLEFYDSSDIKSDLASRDYFSETIQPGKSA
                     QGTAYFEVKNDGTTFEVFFADTSWKGSY"
     gene            complement(15384..15812)
                     /locus_tag="ACG930_002157"
     CDS             complement(15384..15812)
                     /locus_tag="ACG930_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFQ0519312.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKRIEELKNLYGLPESAYRFLI"
     gene            complement(15817..16191)
                     /locus_tag="ACG930_002158"
     CDS             complement(15817..16191)
                     /locus_tag="ACG930_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0519313.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
BASE COUNT         5280 a         2950 c         3219 g         4924 t
ORIGIN      
        1 tttttttttg ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt
       61 tccatatctg ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat
      121 cgaggtagcc acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa
      181 agatcatcag ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat
      241 caagtcaagg aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa
      301 acaaatcagc aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc
      361 ttagccattt tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc
      421 atagccaata caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa
      481 ctaaatgttt taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata
      541 gatatagaag accttgtaat agatgacatt gttattttag agactggata tcaaattcca
      601 gcagatgcag aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa
      661 gcagatgaaa taaccaaaga aataggtgat ccattaatgt ccggcagttt cattgtttcc
      721 ggaaaagctt acgcccgatt agacaaagtt ggagcagatt cgtatatttc ccagctgaca
      781 gtcaaagcca agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa
      841 ttgatcaaat ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt
      901 tactttttta atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc
      961 ggtatgatac ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact
     1021 aaactagcaa agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg
     1081 gtaaatgtcc tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa
     1141 aaaatgatcg tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc
     1201 attgctgact atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca
     1261 tattttacaa aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa
     1321 aaattcagca gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt
     1381 ttgcgcgatc aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat
     1441 cgcgtgttgg tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca
     1501 gtcacaccat taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca
     1561 tttgattact tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc
     1621 accgtatcca atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca
     1681 tctaaattat cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc
     1741 gtcaagccag aacaaaagaa aatcttcgtt caattgataa agcgtaacaa tacagtagct
     1801 atgacaggtg atggcgtgaa tgatattcta gccatgaaag aagcagactg cagtatagcg
     1861 atggcttccg gaaatgaagc cgccatgcag gcctcacaag tggtcttact tgattctgac
     1921 ttttcacgca tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa tattgagcga
     1981 tcagccagct tgtttttagt gaagaatatt ttctcctttt tgctctcact gttttcagtg
     2041 atctttgctc tgacctatcc tttagaacca tcacaaatca cattgattag tttgtttact
     2101 atcggacttc catctttctt gcttgctcta gaagaaaaca aaaagcgaat cagagggaaa
     2161 ttcatcatga atgtgatgga aaaagctgtg ccaggtggac taacagatat gatcgtagtc
     2221 ggtgcgttgg tgatctgcgg ggtgactttg aatctaaata aaacagatgt ttctacagca
     2281 tctaccatgc ttttgattgc agtagggttc ctcgttctct ataaaatctg ttcaccgctg
     2341 aataaattca gaagtcagat cattcttttc tgtgctagcg gtaacttttt ttcggtcatc
     2401 tttttgcata agctgttttc aatcaccggt atctcagctg tatcactttt gctgttgagc
     2461 attctatttt tctcggcaga ttcgattttt aggcatttga ccacattggt agaatatttg
     2521 tttgaacgta aaaatgaaaa agagcaaaag ccgtttagtc gcgtagctaa aaaatttcta
     2581 tcgatattta aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa aaagaacaac
     2641 cactcgtgta tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc
     2701 tcttttttac attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc
     2761 tacagtaatc gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc
     2821 ggtcccgcct gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg
     2881 ttcctgatcc tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc
     2941 tgttgcctga tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc
     3001 aatcagattt ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt
     3061 tccaatcaat cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat
     3121 ttgctggaaa taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt
     3181 tgacagctgg atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat
     3241 ctcaagaaaa gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt
     3301 aaaaccaatc agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc
     3361 cttttgtagc ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg
     3421 tccggtacct tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc
     3481 tgtaagggtg atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg
     3541 aatgagtttt ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac
     3601 gtttaaatgt agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat
     3661 caggaatacg ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt
     3721 acacgcccga tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc
     3781 ttcccattga tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt
     3841 ttttagtacg ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat
     3901 cattcctgca agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact
     3961 ctcagttctc ggtaaaaaaa cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg
     4021 gccacttttt ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt
     4081 gcgcaaagcg ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt
     4141 tcgctgttca ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat
     4201 taaagtaatc cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc
     4261 tgcttggagg ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta
     4321 gctttcttgc tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc
     4381 aaaaaacaaa ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt
     4441 catcgtttgg gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg
     4501 tgttttggat ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg
     4561 ctttgtcctg cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca
     4621 cggtcttttc gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc
     4681 agatggtcgt ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat
     4741 agatattcag gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt
     4801 gctttcatac gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca
     4861 cctatttcta ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc
     4921 ggtgtttcat ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga
     4981 agcatcacat ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg
     5041 cctccatctg tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc
     5101 gttacaatag aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa
     5161 taggtttcat tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag
     5221 aaataaatgg tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt
     5281 ggaatcagtg catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta
     5341 ccagaattga tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc
     5401 ggcggattac caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg
     5461 tggaaagatc aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa
     5521 aatggcgcga tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg
     5581 aaggaaaaaa gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata
     5641 aaaaaaaatg gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc
     5701 tctgatgaag aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg
     5761 aatgaacgcg ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat
     5821 ggaattatat tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag
     5881 ccgacaagca gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa
     5941 aaaactccat cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc
     6001 atatattaca gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca
     6061 agcaatcgaa gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa
     6121 cgtctccagc aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta
     6181 aaagaaatga tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta
     6241 gtcaaagatt ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt
     6301 ttatcacctg cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt
     6361 tctgaaacag cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt
     6421 cttcaagggg caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat
     6481 gaaaatgctc gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa
     6541 ttgaaagtat taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc
     6601 ccggtagaga tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta
     6661 ttgatcgata cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa
     6721 atcaaagaat tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa
     6781 gatgccgtca acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc
     6841 actaaacttg atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc
     6901 gcaccaatca aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca
     6961 gatcgtatgg ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg
     7021 cagcaagact acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca
     7081 ttcgatttca atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa
     7141 gatctaatca aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta
     7201 gatccaaaag atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga
     7261 gcaaatcctg atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac
     7321 agtgttgttg aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag
     7381 caaatgtcca aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc
     7441 aaaggaaaac taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag
     7501 aaaaaacgga aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg
     7561 gagcttttct atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg
     7621 gcacagatga gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact
     7681 gtctggggtg ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt
     7741 aatcaagccg gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca
     7801 tatgatcgat tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta
     7861 atggaaaaca aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc
     7921 aaagcagtct tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt
     7981 tctaatggaa aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt
     8041 cctctttcag atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc
     8101 acaacaatct atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt
     8161 ttccgcaaag aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc
     8221 atattttatg gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa
     8281 tggctttttg acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc
     8341 gatacgacca tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa
     8401 gcaatttatc cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca
     8461 gatgctgagg tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa
     8521 ggaaaagata tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa
     8581 atgattgatg aatggtatat ccagattacc cctgtattat taggggacgg gattccttta
     8641 ttccaaaaag gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa
     8701 tttatcgaat tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat
     8761 gcagaaatgt cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa
     8821 tttgttagaa aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc
     8881 aacgatatta ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg
     8941 ctgcaaggtt ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa
     9001 gccgccgatc ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact
     9061 gtgtccataa ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg
     9121 gttgtattca ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg
     9181 agtccattca gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc
     9241 atcgattttt acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc
     9301 tacttttttg ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt
     9361 catacgattt ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga
     9421 gcaaataaaa acacttactg acaaaagcta catagaagat agattactta tttttaacaa
     9481 aaaagaagtc taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga
     9541 aaaaaagctt tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg
     9601 aggtggaaat aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt
     9661 ccgttttacc gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa
     9721 actgtaggta cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta
     9781 gttcttgact ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca
     9841 aaagaaggcg ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg
     9901 atatgaaaga tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg
     9961 atcaagtcaa gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg
    10021 ctcctgaaga tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca
    10081 caatcgttta cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg
    10141 ataaggaaaa gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt
    10201 tttattaatt gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga
    10261 ggagggagtg aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta
    10321 agcgcttgta gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct
    10381 gaaactgtta ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca
    10441 atggctacct caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca
    10501 aatgttccca tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca
    10561 catacaaagc aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat
    10621 gctgacgaat tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct
    10681 tctagtcaag aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa
    10741 gtggacttag gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt
    10801 gaatggcaag aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat
    10861 cccttactat tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct
    10921 gaacaatttg gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta
    10981 agctggcaag aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg
    11041 aagatggcag tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt
    11101 aactccaagt cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct
    11161 taatacctta aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa
    11221 aaagaaatgg ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca
    11281 aggtatcaaa ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa
    11341 aaaaggaacg gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa
    11401 aagtcatcgc aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa
    11461 tgatgtggaa aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct
    11521 agctgaaaat gaattctatt accatgagat catcggtctg catgtattag aagatggaac
    11581 tgagttaggt aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca
    11641 acgtccgaaa aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga
    11701 tttagaagct ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg
    11761 atgtattgac tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta
    11821 aggctgtaga taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata
    11881 acaaacatca gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag
    11941 tccagcccat ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa
    12001 gagtaattct tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt
    12061 cacaagaaga acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc
    12121 gcacattagt gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag
    12181 gtgcgatggt catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga
    12241 cttcagctca aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc
    12301 cggcagaata taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga
    12361 ttgaagaatg gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt
    12421 tggaaacact tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag
    12481 aacaagaaaa aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg
    12541 ttgataatat gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg
    12601 ctgtgagaaa agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa
    12661 tcgaagaatt aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca
    12721 ctgtgcgtgt tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag
    12781 gtgttgttat caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt
    12841 ctaacggagt gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg
    12901 aagtagttcg ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg
    12961 gaaaagctgc tcgtatcaaa gaaatccgtc gttaatcatc gttatcagac tgagaaagaa
    13021 cccttggtat tcaagggttc tttttttgtt ctctgttttt ttatattaac gatttctatt
    13081 tgggacattt ttgattaata aaaaggggca aaaaaggggc aacaagttac agtttttcta
    13141 tatcttcttt caatttttct tttactccct ttgtcacatg caaataaatc ttttcagtga
    13201 tatcactatt ttcgtgccca acgcgatcct gaatagcata cagaggagtt cctagttccg
    13261 ctaattttga aatatgggta tgtctaaaaa tatgtgaact aagtttttta tcaatcttca
    13321 tgtcagcttt atgatttctc aaataggtgt taattgctgt tagttggaaa ggagttcctt
    13381 tcgttgtttg aaatagaaat tgaccattcg gatttaattc tagaagctca ttgtaaatag
    13441 ctatcgcttt ttttggtaaa tcaatttctc gcattccagc agcagttttt gtagaatcag
    13501 attttttcat atcagctatt gaacgttctc tatacatcat cgtcccattt ataactactg
    13561 atgcattatt attggtaatg tgtacatcgt ctttacttaa tgcgattgct tctccaggcc
    13621 tcattccagt caaatatagc cactggaaaa ggagagaata tcttttattg tgtgaagttg
    13681 tgaaatttac tagtctttta tattcatcat cttctaaaaa cttatcttta atttttatcg
    13741 tttttgactc tcgtttataa tcaataacta cttcgttgat aggatttttt tctacatagc
    13801 cttttttcat agcgtatgaa aaaagaagat tcaatttgga tttaattaca ctgacgtact
    13861 tatttgacaa gtcatcttta tatatcatat cttcaaaaat attatttaaa tctactgtat
    13921 taataccaga aacgatgtaa gtctcaggta tctttttctt tatagtgttt aagatattat
    13981 tcgtaggata atatgtagac tccttaactt gtcttttgta aataactaac cattcttcga
    14041 caagctcatg aaatgttaga tcaggcttct gaagtgtttt ttcgtttaat tttatatcaa
    14101 tttttttatt taactctagc aatgccactt tctgagtttc tcgagattta tttttataag
    14161 taatgctcac tttttttctt tttctagttt ttggatcaat atatcgctca ttatatttat
    14221 atactttttt tccgttttta tcagttttgg tttcaatcca cattgttttc atctcctatt
    14281 tgttgctata ataggaatgg ataagtaagc caattatagc aggtttattt ttcatcacgt
    14341 ccacaaactt tggcgaggga gggggcgtgt ttttttgttt agtagctacc tttccatgaa
    14401 gtatctgcga agaacacttc aaatgttgtt ccatcatttt tcacttcaaa atatgctgtt
    14461 ccttgtgcgg atttacccgg ttggatggtt tccgaaaagt aatctctact agctaaatca
    14521 gatttaatat ctgatgaatc ataaaattct aaataacttg aacttgcatc aaaaggtgta
    14581 gtccctgtgt tttctacaag aaaatctacc tttgcgtaaa ataggccttc tggtttatag
    14641 aaatcatcac cgtaatcttt tgatacagac tggacagtta cgttaataga gttaccattt
    14701 tcagaagtaa aaggaactgc ttctcctata ctatgtgcaa ctgatgccgt ctggggttct
    14761 gaagacgaag ttgtagttgt agttgtagta gagcttgaat ctttggattt tccatcttta
    14821 tctaagaaag ttcgttgatt ataatataca acctgttcag tttttggact aacccaaatt
    14881 aacattgttt catcatcaga atcagttgaa taagtatatt ggagcatctc taattttttt
    14941 atatcttttg cactatttcc atgttcaatt aattcagagt gctctttata ataatctcct
    15001 tgtgcatcct ttgaaataga tacaattaat tcatcccgtg tgatagcatt gtctaattct
    15061 ttgtaaacaa aatcatttgt ccatttacgt aacggtgaac caagtgtctg ataaacttga
    15121 gttaaatcat caccaacttt tattttatga acgtctgatg aagttagttt ttttgtttca
    15181 tattcagatg ttgatgaaac agtattttct ttagtgctag cagaattagg actagtggag
    15241 catccgctta ataccaagcc taaaaaaagc aacccaaaaa caattttttt catttttaat
    15301 tcctcacttc tatgatatga tttttttgta ggatcttaga aataaggttt ttagtccgtg
    15361 ttgcagcacg gacttttttt acattatata agaaagcgat aagcgctttc tggaagtccg
    15421 taaagattct ttaattcctc aattcgttta ggatattgat cattgtcttc tttgtataga
    15481 gaaacaatga gattagcagc aaagcaatta gcttcgcttt cagatttgct tctagatgtt
    15541 cttgttgata catagtaact ggataagcca cgatgaaaaa tagcgtgacc taattcgtga
    15601 gcgcaaatgt agaatctttc ctcagagtct ctcagttcat catttaagaa gattattgca
    15661 cgacctctaa tttcttgaaa ctgtcctttg ggattctcga taaaaggaac gtattgaatt
    15721 ttaatgccca tcttttcaca aatataaaaa ggattagcgg actggtattt ccgcttcaac
    15781 tcctcgacta aattaatcgt atccatctcc ataagctcac atctttttgc ctttttcttt
    15841 gtcttctttc acaatatccc agaaggttcc aataaggata tcttttacgc gttggacctg
    15901 ttcaggcgtc agtgtttctc cgccataaga catattgaca tttgaatcta gtaatttatc
    15961 aagttcaact acttcatctt ttgttgccca gtcaggaact tggtttctac cgagtaaata
    16021 atcagtagtt acattaaaat aatctgctac aagttgtagt cttttagtac taggagttct
    16081 atttttccat tgataaatcg tgtttttagg tatatttaat tcttcttcca attgagttat
    16141 acttatgcct cttttatgag ctaattcctt tattctatct agtaaattca ttttcgcacc
    16201 tcacaagcta cgaaaacact aataaaaaaa ttagttaaag gtgttgacaa ctaataaaag
    16261 tgttagtata ctgttttcgt aagctaaaat attagctaaa aagacttgat aactaataaa
    16321 cacttcacgg tcggcaaact ctgaaatgta aattactagg catttctgtg tct
//
LOCUS       DAZKPE010000061        16270 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000061 DAZKPE010000000
VERSION     DAZKPE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.061"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(89..586)
                     /locus_tag="ACG930_002159"
     CDS             complement(89..586)
                     /locus_tag="ACG930_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFQ0519314.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(716..1426)
                     /gene="budA"
                     /locus_tag="ACG930_002160"
     CDS             complement(716..1426)
                     /gene="budA"
                     /locus_tag="ACG930_002160"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFQ0519315.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(1439..3103)
                     /gene="alsS"
                     /locus_tag="ACG930_002161"
     CDS             complement(1439..3103)
                     /gene="alsS"
                     /locus_tag="ACG930_002161"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFQ0519316.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(3308..3970)
                     /locus_tag="ACG930_002162"
     CDS             complement(3308..3970)
                     /locus_tag="ACG930_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFQ0519317.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(3980..4795)
                     /locus_tag="ACG930_002163"
     CDS             complement(3980..4795)
                     /locus_tag="ACG930_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0519318.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(5057..5500)
                     /locus_tag="ACG930_002164"
     CDS             complement(5057..5500)
                     /locus_tag="ACG930_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFQ0519319.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(5634..5972)
                     /locus_tag="ACG930_002165"
     CDS             complement(5634..5972)
                     /locus_tag="ACG930_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFQ0519320.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(5960..6337)
                     /locus_tag="ACG930_002166"
     CDS             complement(5960..6337)
                     /locus_tag="ACG930_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0519321.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            6561..7754
                     /locus_tag="ACG930_002167"
     CDS             6561..7754
                     /locus_tag="ACG930_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0519322.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(7920..8342)
                     /locus_tag="ACG930_002168"
     CDS             complement(7920..8342)
                     /locus_tag="ACG930_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519323.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            8713..9387
                     /locus_tag="ACG930_002169"
     CDS             8713..9387
                     /locus_tag="ACG930_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519324.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            complement(9549..10721)
                     /locus_tag="ACG930_002170"
     CDS             complement(9549..10721)
                     /locus_tag="ACG930_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFQ0519325.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(10927..12216)
                     /locus_tag="ACG930_002171"
     CDS             complement(10927..12216)
                     /locus_tag="ACG930_002171"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFQ0519326.1"
                     /translation="MKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKD
                     TAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLPF
                     YNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQFVT
                     GFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQKET
                     TFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHFIKQ
                     DVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKLISD
                     SEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQPKG
                     ILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(12353..12868)
                     /locus_tag="ACG930_002172"
     CDS             complement(12353..12868)
                     /locus_tag="ACG930_002172"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFQ0519327.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(12941..13855)
                     /locus_tag="ACG930_002173"
                     /pseudo
     CDS             complement(12941..13855)
                     /locus_tag="ACG930_002173"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(13852..16179)
                     /locus_tag="ACG930_002174"
     CDS             complement(13852..16179)
                     /locus_tag="ACG930_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFQ0519328.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         4647 a         3249 c         2875 g         5499 t
ORIGIN      
        1 ataaaaaaac cgaaaaacag aaatgcccac tgtctttccg gctcttttta ttcttgattt
       61 ctcttctttt ttgtttcaat agacgatttt agttattaat aaatgaaaaa gcatttatat
      121 taaaatttgc taataaaaga tctacatatt tttctagaaa tgcttgatcg atttcatcat
      181 accctttcgt tactccgcaa tcgatatcta aaacaccgat taaattacct tcttttacca
      241 ttggcactac gatttctgat tgtgcggctg aatcgcagga aatgtaattt gcatgggttt
      301 tgacatcatc aacgatcaat gtttcttgtt tttcagctga ttctccacaa actccttttc
      361 ccatcttgat acgtgtgcaa gaaactcgcc cttggaacgg tcctaaaatc aattcattac
      421 catcgaataa ataatatcct gcaaagacag tctcaggcaa agtctcattc aacaatgcag
      481 atgaatttgc taaatttgct aaccagttat cttctgcttc taataatcct tgttgctgta
      541 ataataaaat ttcgtatgca tcttttttct gtttttctgt ccacatgata aaaaccgctc
      601 ctttttgatc tatggagaag attatagctc agtttttttg taaacgctag gtttcctcct
      661 caaaaaaacg agatacgtca ggttaatcac cttgaacgca tctcgctgtc tttttctatt
      721 ctgcttgttg gatttctgct gctaaatcag cataatcaat cgtttcgtga acaaaagtcg
      781 gatcatcaac tggaaaatgc tgtacaaggg acgagatgcg gctaatctca acttttcctt
      841 cagccacttc aaaatccatt acatgtccgc caaatgtatg tgtatcatcg ataaaatgca
      901 agtgaaatcc cgctgcagca actccttgga ataattcagg cgtaaagaac ccgactaatg
      961 ttccttggac attgctttgt tggaattctg gttgagactc tgaaattttt gctagtcttc
     1021 tgtaaggttt ttcttgcttc ggcatgatac ggatgtgcat atttttgaat aatccagtta
     1081 tcttcactgc caaaaatagg ttttccccgg cttctcttac taatatgtct tttttcaatt
     1141 gttctccatc tgcagttttt gagacagaaa aactagtatc tggcgtaaaa tctgtaattg
     1201 ctgcataggg ggtaagttca cttccatcta attgggcaac tgagccatct gatcttcctt
     1261 gataagctac gccatctaaa aagatgactt caccatcaag cccatgcaat gttcccaatc
     1321 ccagagttcc tttttctaat atatgagcaa tcgtttctgt tccatccatc aagccagcca
     1381 tcaaagctcc taatgtcccg tgctggtata agattttttc agtcatgtcg acacttcctt
     1441 aatagaattg atctggtaag attgtttctc ccaatttctc attatcacgg taatcaatcg
     1501 gaatatcaat aattacgggt ccttctgtcg caaatccttc ttctaaagct ttttctaatt
     1561 cctctacact tgtagctcgg attcctttag cgccaaaagc ttctgcatat ttcacaaaat
     1621 caactggacc aaagtctaca cctgacgccc gctgatattt cattttttct tggaactcta
     1681 ccatattgta gtgtccatca ttccaaatca aatgaacgat attcaatttt ttacgtaccg
     1741 ccgtttctaa atcctgggca gagaataaaa atcccccatc gccggaaact gatacgattt
     1801 gtgtatttgg acgcaccaat gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt
     1861 gcataccatt actgaataac aaatgacgag gttcataact tctaaagtgg cgtgccatcc
     1921 aaatataatg actacctaca tctacggtaa cagtcatatc atctgttact tttgactgaa
     1981 gcgtgttaat aacttctaaa ggatgcaaga tacctgcttc tccttttgat tgaacaatgt
     2041 cccgctccgt taattctgct tgaagagatg ctaaatattc ttttgcatct tctgacactt
     2101 gttgaggctc taatgaacct gtcaataaat caagagtggc tgagatatca ccgatcaatt
     2161 ctctttcagg ctgcataaaa ggatcgattt cagctggcgc ttcatcgatc acaatgatcc
     2221 gcgcatcttt ttccgcattc cagtttcttg cttcatattc gattggatca tagccaatag
     2281 caataactag atcacttcgt ttcaaaagca tatctcctgg ttggtttcta aataaaccca
     2341 cacgaccaaa gaaatgcgct tctaattcac gtgagatcac tccagctgct tggaatgtct
     2401 ctacaacagg caatgctgtc tttccaacta attgcctgat ggctaacgtt tctttttcac
     2461 ttgatcctcg catacctact aatagtaccg gtagttttgc ttctctaatg cgttcagcta
     2521 ggtaacggat atcatctgca gaagcagaac ctaatttagg atcgctcaat ggcttgatga
     2581 cattcccttg gacaggtgca tccactacat cttgcgggat actgataaag ctcgcgcctt
     2641 tttttgaact cttagccata cgataagcat tggcaatcac ttctgaaatt gtttctggat
     2701 cttggatttc tgcactgtat tttgtgattg gctggaacag tgctgcatta tccatgcttt
     2761 gatgggtcaa cttcaataga tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt
     2821 caccttctgc tgtcgctgtt accaaacctg tagctaagtt actagcacca ggaccacttg
     2881 ttgcgataac tactcctggc tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag
     2941 cattttgttc gtgacgagtc acgattaatt caggaccttg atcctctaat tcattaaata
     3001 caccatcgat ttttgcacct ggtataccga atacataatc aacatgatga ttaatcaaac
     3061 tttctactac agatttcgaa ccttgtttca ttttttcgtc cattgaacat cgtccttttt
     3121 atgctttatt tttaattatt agttagaaat aatcacaaat aattgataca gtttctaaac
     3181 ctgtttcatt caaaagtata gcacgtttta tttcatttgt ttagccatat gtttcaaaaa
     3241 atgaaaaaga atgacagttt ttacataaaa actgtcattc ttaattgaaa gtttcaattt
     3301 ataaagtcta cagatccata gttctcatca atttacgatt gttgaagtaa atcaaaccaa
     3361 atacgataga aggacctagt agaatacacc attggggctt tacgaaaaag aagagaaaca
     3421 aacttgtcaa tagtaaaaaa tctagtaaac tcacatacca ttttttcaac gtatagtaga
     3481 acgctatccg tagaacttga tttggtttcg acgctggatt tctcacctga aaataccagt
     3541 agttgatgct aaaggaaact gataaacaag caagtaaaac aaacaacgga atcaaccatt
     3601 ttccataaga aaaacgtata aaaaagaaac aatcaaaaat cattatcaca ctaactatcc
     3661 aagcaaatag ccaataaaaa aatcccttta gccaaaattg gcgaaacgtc tttatgaaca
     3721 aacgtactgg tgaaaaactt ttttcttttg ctaattcttc tgtcatacct atcatcacga
     3781 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
     3841 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
     3901 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
     3961 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
     4021 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
     4081 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
     4141 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
     4201 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
     4261 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
     4321 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
     4381 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
     4441 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
     4501 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
     4561 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
     4621 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
     4681 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
     4741 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     4801 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     4861 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     4921 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     4981 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     5041 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     5101 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     5161 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     5221 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     5281 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     5341 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     5401 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     5461 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     5521 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     5581 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     5641 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     5701 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     5761 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     5821 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     5881 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     5941 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     6001 catatttctt gatttttcct tgtaaacgtt ccaaacattc ttgcatttca gcaatttttt
     6061 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     6121 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     6181 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     6241 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     6301 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     6361 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     6421 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     6481 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     6541 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa gttattatta tcgacatcgg
     6601 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     6661 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     6721 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     6781 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     6841 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     6901 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     6961 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     7021 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     7081 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     7141 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     7201 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     7261 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     7321 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     7381 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     7441 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     7501 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     7561 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     7621 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     7681 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     7741 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     7801 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     7861 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggctac
     7921 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     7981 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     8041 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     8101 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     8161 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     8221 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     8281 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     8341 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     8401 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     8461 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     8521 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     8581 ccgtgtatca aaacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     8641 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     8701 ggaggaaatt tagtgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     8761 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagctcaggc ttccagcagc
     8821 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     8881 aaaaaagaag aagagaaaca aaaagcggaa aaagctgcac tagaaaaaaa agtgacagaa
     8941 gcggaatctg ctttgtcaca agctgaagca aatcctacaa aagaaaacta tgcaactgct
     9001 tcagcagcta tccaagcgct acctgaaaac aaacaagagt tgacaagccg tcttgctgca
     9061 attgattcca caatcaaagc aaaagaagca gaagaagaac ggaaaaagca agaagaaatt
     9121 gcacgacaac aagcagaaca agcgcaacaa gaagcaatcg cacagcaaca agcagaacag
     9181 gcgcgacagc aagcagcagc tgaacaggcc tctcagcagg cacaagccgc agctcctgag
     9241 caaaataatg aacaaactgt ctatgtcaca ccgaccggtt caaaatacca tacacataaa
     9301 tgtggaaatg gtacgtatac ccctgccact ttaagcgaag ctcaagctcg tggtttaacc
     9361 ccttgctcca aatgttatgg aaactaattc aaaagttata ctataataat aaaattcttc
     9421 tgaaacataa aaaaatagaa gctggcgttc cagatagtaa accaaaaata gcagtttaca
     9481 cgtccatttc gtcagcttct ctcttttttc atttagtctg ttccctctgc ttttttggac
     9541 atcttcattc attctttctc aatcaaatag tacacctctt tttcttttcg cagtttatat
     9601 cttccttttt tcaatttcat tgaaaactgt ttcgaatgtt tatgttttac atggatttta
     9661 agcaggagct cctcatgttg caagcgatag ttcctgcctt ttaaatcaga aaatctcact
     9721 agtccgtatt catcagaagc tttcacaaat ggaacttttt ctctagtaat atagtgtttg
     9781 ccgttgagcg tttttacaga aaagaccatt ccttcgattg gtcgtccgtt tgtgttcttt
     9841 acataaaaag ataaaggata gtttcgctta gcgatggcca aagaatctaa ataagcgatg
     9901 agtagccaaa ctaagccgat tgatccaagt agtataccga taaaccaaat aaaaaatttc
     9961 cattttttcc attgatcaat tccttggatc gctttttttg cctcttttgc ttgataagga
    10021 atacgatgcc ccgtcacaag cagtcgatgt gtattgacca tataaggagt acaggtaagc
    10081 aaagtcacga gatctctgcc tttttggata cccaaagaat ctacttcatc aggtaagacc
    10141 acttggattt tttctacttg atacgccaat gtctttccat tgatctggat gaaaaactgg
    10201 tctccttttt tcaacttagg caaatctgta aataattttg cttctgggag tccacgatgc
    10261 ccagaaagaa cggcatgggt gtttttcccg ccagtcggat aagaactttc ttccaataat
    10321 gacgttcctt tttgcaaaaa tatttccgtt gtctgatcga atataggtaa gctgacattg
    10381 atttttggga tttcgatgac tccaagcata tgttccataa aaaaggcatt actaggtaaa
    10441 tcttttaatg cttttgcatc aactgcttgg ttgaaactgc ctatccctgg tgatacgttt
    10501 tgctctgcca actgttggtt tttctttgtc attttttcct gctgtttttt tatttcctct
    10561 gaattcttat tcgatgcttg cttttgataa tggatgatca tttgctgggc aagaaaatca
    10621 ttcagtgaat cttctacaaa aggataagaa aagatcccga tcccaacgac taaaatgatt
    10681 gccatgaaga tgtccagtat tcttattctg cttttattca tcatgtccac ctattttcta
    10741 atatgtatat gaagaggttg tgaaatcagc gccttgacct gagtattcgc tcaacaaacg
    10801 gcaaaatagt tcctcctatt ttgccgtttg ttgagcgaat accaagagac cgaccacttg
    10861 tcacaacctt tctccccatt tgaatcacta tcgtttattt atcgtatgat ttttgtttcc
    10921 aatagtttaa gcttctgttt cttgatggcg ttttttgaag tagatcactg ctcctccaac
    10981 taaagcagta cctaccaaga tgaatacgat gatccccata ccaccagttg aaggcaagat
    11041 tcctttaggt tggttatcga tcgttgtttc atcagaagtt gttggatcat catctactgt
    11101 aaattcagtg tacgcagctt cattcttagg taatgcgtag ccttctggtg cttttgtttc
    11161 ttgaaggcag tatgcccctt gtttcagccc ttcgattgaa aatttccctt ctgaatcaga
    11221 aatcaatttc acttcttccc agtcagaacc tgtgacttca tctgaccaag catatgggta
    11281 ttctcctgag gcaagatttg ctattttttt cattaattta acagttggat cttttgctct
    11341 tagaatagaa aattctgcat cggctaattt ttcttgcgtg ttcacatctt gtttgatgaa
    11401 gtggaaatca ccgtagtttt ggacattttc tacagtaatc gtgttatccg tagttgtatt
    11461 ttcccgattg actacaccgt ttggattccc aagattggct tcatctgcgc catggatgat
    11521 accggttgtt tgttgcaatt ttccgttttt tactataaaa gtagtttctt tttgtggatt
    11581 ggttaattga taaccatctg gtgcttttgt ttcaactaaa gtataattgc cgtctattaa
    11641 tccattgaca ctgatggatc cttcagtatc agttgtgaat gtcaacgctg actcagcagg
    11701 atcatagaga gcgacaccag tgttttcatc aaaaccggtc acgaattgat tctctgaatt
    11761 tttgatctgg aattgcgccc ctgctaactt atctacccct gaaaagttcc cagctttctg
    11821 gattttgata ttgctttctt tgatgacatt tttagcatat aggtgaatcg tgtctaaagg
    11881 tttgtcaggg tctgatgaat tcgggttata aaagggtaag cttaacacga tatttggcga
    11941 cgtttcgaca ccgggctttg gtgtttctac aaagacgtat acagcatctt tcccatcaga
    12001 tttacctgga agagtcaggt tagctaatcc ttcaccagaa gtcgttacac ttgcgaaggg
    12061 tgtagcgtct gctggaactg ctgtgtcttt acttggatag tacgtagcag tgatgtcata
    12121 tacgttgaat tcaacgccgt tcaacggttc gctattcgga aatgtcaatt ccgttccgtt
    12181 gtttatttga ttttctggtg ctgaagtgaa tttcaattta tgcaaattaa ccgtaacatt
    12241 ttctggtgta ggtgatacgg cctagaaacc tctgcagttc ctaggccgag aacgaaagga
    12301 agcagcatga tagcagttcc taaaaacgtc catatttttg ttttgatgtt tttcatttta
    12361 tttccctcct attgtttcct ttttgttgtt ttttataaaa ccaagctgtc cctgttgaaa
    12421 ggactagcaa caaccctaaa attgagaaac ctccaagcat ctcttcgctt gtttttggaa
    12481 agcttcctcc atttttttca tttgatggac catttgtctg catctgaact ggcgtttttc
    12541 cattattcgt cggatttgct tttggttcgt tgatgatttc caatggtata ggatgaagcg
    12601 gatcataact gcctttttca acttcaaaga gaatggttga ttgactcaat atatatcctt
    12661 taggcggttt aatctccact agttcgtaac ttccaaaaga caatccatgg acagaaaatg
    12721 ttccatcttt actggaagta aaaatcgttg ctcttgaatc atctttggct acccaatgat
    12781 ttatcccgtt ttcttgcgct aagtattggt catttttttt gactagaaat tgagcatctg
    12841 ctagtttttg tttcgtttgc cgatccactt tgacaaattg tttgcctcct gtttggatgg
    12901 caagatgtgt ttctactgtt tgattgtcag tcgtcaaacg tacatcgtta tcaaatgtcg
    12961 ttttttcact gttttctttc aatgtcattt ggtaacggat cgttaatttt ttcccagcaa
    13021 acgaactaag atcttttcca gaatctgata agacaaaacc atgttttgtt ttttgtgtgt
    13081 gaaatgtatg aatcttgtct ccaccaatca aaaaatcgat cgtttctggt tctagccata
    13141 actgaggatc agctgtatct ttgatcgtat aggttcctat ctcgttgatg ttctcaggaa
    13201 ttgttacggt gatgagataa ggaactttat ccccatctgc aaaatctgtc tgcttattct
    13261 ctactgtttt tgttaatgtg agtgcagcag gtattttttg ttcgctcttt ggatacaagt
    13321 ggatggtcgt caatttatga ttagatgaat ctgtcacagg aagcacaacg acaaatggtg
    13381 ctgatttttc ttttacttaa tctgaagtct ttatttccgc aaatcggtaa acagcgtcac
    13441 gaccttgctc atctttgtcc gatgcactaa aagaagcaat gccctcttcc tcgtctactg
    13501 tttttgtcac attttctgcc agtatttttt cactatcact tttttgtgct agttttcttt
    13561 gtgcgtcttc cacactactt ccttctgacc gcagcttgta aaattcatcc gagacatcat
    13621 atatagcgaa agtaacgccg ttcaaccctt ttactccttg aaagttatcc gggatattta
    13681 ttccgtcgtt ttgactgata cttggcatct tatcgctttc gaacattcga ttatgcaaag
    13741 taaatgtaat aggtgattct ctagctgaca cagtcggaga acctataaaa aagaccagta
    13801 ggataaaaaa gagaacagca aatatatcca cacgtacatt ttttgttttt ttcatcgctg
    13861 ttcacctgct tttttcttac gatggataaa ataaaagaag ccagaaaaaa taaagatcag
    13921 tcctaaaaag acaaagggca gtagacctat cccacctgtc gaaggaagca agagagtcgg
    13981 attgatcgtc aacttagcgg tatctgttgc gataatcgta taattattgt ttacacttcc
    14041 ttcgcctaaa ctaatcgtta ctatttgtga tccaatatct gtccggctgt taactgttag
    14101 ggtataatcc aatgattcgc ctaagacaac accggtaacg tggagatttc caaccgaaat
    14161 cgagtgactt tgggcatcat aattaaaggc agcgtcatcg acagtaatca ctgcgttagc
    14221 tttatagatg gtataagttc ctgatgtgtt ggctatatca gtaaatgaca acttgggatt
    14281 tgctgctttg actttgtcta ttccgctatt cgttagttta attgtatagc tgccagcatt
    14341 aaccatattt tttgctgatt gtgcatctgc tgtgtaatcc atactgctaa gtgccacttg
    14401 tactggagta agcgaactag tgacaccctc tgctagcttg acatggattg acgggacacc
    14461 tgcttttcca tcatatgtct tactgccact gagctctacc gcaccgctga tttgcttaat
    14521 cgtatagaca tcagatgtct gcacgatagt aaataaatag tttgttctgg cagctagttt
    14581 agctagtccg ctttttgtca attgccaaga cgtataggtt ccaatttcag taggcgcagt
    14641 tacttcaact cccttttcat tcatcgcttt gaaatcagtt ggattccatg tgatttgatc
    14701 aatactgaga tcattgttta aaagggatgt tgattctgtt ttatcattaa aggcatattt
    14761 aacgatcggt acaacagaaa gaccatcata gtacttactg ccatttgcat tgattgatac
    14821 tgttgcattt gtcttataat ataggatgac ttcagaaatc tgttttccat ttgcgtcctt
    14881 tacgattaca tttccatttg tatctaaact agctaaaaca ctcattgctg attggttctt
    14941 tgtttctgtc gctgaaacag ctgtaaaggt atatccgttg atagtaggcg tattagtcgt
    15001 caggtcttgt gcagcacttc cgtaagtaag attcattatt ttagaaggag caatcatctg
    15061 tccaaaatag tcttgatact taatagtgat tggtgtttgt ttgcctgtat aggtcaccgt
    15121 atcgacgtta ctttctaggg ctgtgaaaga accgtttgtt tgtgcaaaag aatagcccgt
    15181 tactgctgtt ggagtgataa ccactttgtc acccacatgg attccagata atgtagtccc
    15241 gtacgttccg atttttgctg ctccaccatt gactgtataa gaaaaagttc ctgtccgatt
    15301 cgcattgacc tgaaccgttg ctgcttgata ggttggaaaa tttgaaacat ttcccttacc
    15361 atcaacgatc tgcccatttt tgatcgagta ccccgtgaat ggaatatcat ttgctaactg
    15421 tataccgatt gaaaaagtac tcatacctcc tccggcagga agccctcccc atgttgaggg
    15481 tgtaaaagaa taacttttat ccgcattggg tgtaactgaa tcgatcgtat ttccagcggt
    15541 agccaccccc atatagatac tttttgggaa tgtgatagta gtaccattta ctgtggagcc
    15601 aataaacaga ttatggatat ctggacggtt atcaataaaa gcgattgctt tggttacgcc
    15661 ttgtaacgca gttttatccg cactcatcga tccgttaacc gcaacaatga ctccatcttt
    15721 ggcatatatc actgtatatc catctggtat ggtatgtccg ttgaaattcg cagtggccgc
    15781 aacagtacta aatgtctggc ttctacctgt ttctgaataa gctttctccc ctgctgcttt
    15841 tgctgctgtg atttcttttt ctgtcggatc aatcagttga gtcgaggatg tggttgaggt
    15901 tgtctcgttg ttgctagact gattggtgct ttctatggac tgtatttcag aatagggtgg
    15961 actatttgtc tcctctgtcg tttggttagc aaaatttgac gtttctgtat aaacgtttac
    16021 ataaatactt gataagctcc ctaagaaagt aaaaatcaag atgatcgaaa tcataatggg
    16081 atgtaagtat tttcttttag atacagcttt gagtctagaa acaaaatgtt tttgacatat
    16141 acgttggatt ttattttgag ttttcttaat cattttcatc cctcctctca ataaaaaatc
    16201 atcaaataat cctttacacg ttattctaaa tttaattttt attattttat tgatgtatag
    16261 aaagtttggg
//
LOCUS       DAZKPE010000062        16247 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000062 DAZKPE010000000
VERSION     DAZKPE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.062"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            226..894
                     /locus_tag="ACG930_002175"
     CDS             226..894
                     /locus_tag="ACG930_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFQ0519329.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1414)
                     /locus_tag="ACG930_002176"
     CDS             complement(1094..1414)
                     /locus_tag="ACG930_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519330.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(1451..2833)
                     /locus_tag="ACG930_002177"
     CDS             complement(1451..2833)
                     /locus_tag="ACG930_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFQ0519331.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="ACG930_002178"
     CDS             complement(2989..4176)
                     /locus_tag="ACG930_002178"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFQ0519332.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="ACG930_002179"
     CDS             complement(4183..5214)
                     /locus_tag="ACG930_002179"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFQ0519333.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="ACG930_002180"
     CDS             complement(5260..6684)
                     /locus_tag="ACG930_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFQ0519334.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="ACG930_002181"
     CDS             6859..7764
                     /locus_tag="ACG930_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFQ0519335.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="ACG930_002182"
     CDS             7855..8532
                     /locus_tag="ACG930_002182"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFQ0519336.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="ACG930_002183"
     CDS             8529..8699
                     /locus_tag="ACG930_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519337.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8813..9709
                     /locus_tag="ACG930_002184"
     CDS             8813..9709
                     /locus_tag="ACG930_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0519338.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="ACG930_002185"
     CDS             complement(9764..11134)
                     /locus_tag="ACG930_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0519339.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="ACG930_002186"
     CDS             11372..12118
                     /locus_tag="ACG930_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519340.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="ACG930_002187"
     CDS             12115..12954
                     /locus_tag="ACG930_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0519341.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="ACG930_002188"
     CDS             12955..13905
                     /locus_tag="ACG930_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFQ0519342.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="ACG930_002189"
     CDS             14046..14798
                     /locus_tag="ACG930_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519343.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="ACG930_002190"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="ACG930_002190"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFQ0519344.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5281 a         3019 c         3253 g         4694 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agtttttgtc cagtaattgt tgtaacaatt
    16021 actggttttt ttgtattttt tacatttttt taagagaatt tgataaaaat caaaaatttt
    16081 tttgcttttt tttatggatt attgcagtga atgttacaga atctgcgttt ttcattcaaa
    16141 aataaaaaaa catagaaaaa cgattacttt gcttatacaa caaggctttt atggttttgt
    16201 atcaaaaaaa tatttgttta aatgttacaa atattaaata attcgtt
//
LOCUS       DAZKPE010000063        15661 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000063 DAZKPE010000000
VERSION     DAZKPE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.063"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..197)
                     /locus_tag="ACG930_002191"
     CDS             complement(<1..197)
                     /locus_tag="ACG930_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0519345.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDV"
     gene            complement(417..783)
                     /gene="ssrA"
                     /locus_tag="ACG930_002192"
     tmRNA           complement(417..783)
                     /gene="ssrA"
                     /locus_tag="ACG930_002192"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(954..1727)
                     /locus_tag="ACG930_002193"
     CDS             complement(954..1727)
                     /locus_tag="ACG930_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0519346.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1871..2221
                     /locus_tag="ACG930_002194"
     CDS             1871..2221
                     /locus_tag="ACG930_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFQ0519347.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2202..2918
                     /locus_tag="ACG930_002195"
     CDS             2202..2918
                     /locus_tag="ACG930_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFQ0519348.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2918..4366
                     /locus_tag="ACG930_002196"
     CDS             2918..4366
                     /locus_tag="ACG930_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0519349.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4436..4945)
                     /locus_tag="ACG930_002197"
     CDS             complement(4436..4945)
                     /locus_tag="ACG930_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519350.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4935..5660)
                     /locus_tag="ACG930_002198"
     CDS             complement(4935..5660)
                     /locus_tag="ACG930_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519351.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(5883..8003)
                     /locus_tag="ACG930_002199"
     CDS             complement(5883..8003)
                     /locus_tag="ACG930_002199"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0519352.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8233..9411
                     /locus_tag="ACG930_002200"
     CDS             8233..9411
                     /locus_tag="ACG930_002200"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFQ0519353.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9427..10185
                     /gene="aroD"
                     /locus_tag="ACG930_002201"
     CDS             9427..10185
                     /gene="aroD"
                     /locus_tag="ACG930_002201"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFQ0519354.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10208..10693
                     /gene="ybaK"
                     /locus_tag="ACG930_002202"
     CDS             10208..10693
                     /gene="ybaK"
                     /locus_tag="ACG930_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFQ0519355.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(10764..12017)
                     /locus_tag="ACG930_002203"
     CDS             complement(10764..12017)
                     /locus_tag="ACG930_002203"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0519356.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12134..13483
                     /gene="gdhA"
                     /locus_tag="ACG930_002204"
     CDS             12134..13483
                     /gene="gdhA"
                     /locus_tag="ACG930_002204"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFQ0519357.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13595..14941
                     /locus_tag="ACG930_002205"
     CDS             13595..14941
                     /locus_tag="ACG930_002205"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFQ0519358.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15249..15635)
                     /locus_tag="ACG930_002206"
     CDS             complement(15249..15635)
                     /locus_tag="ACG930_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0519359.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5125 a         2794 c         3153 g         4589 t
ORIGIN      
        1 tatacgtctt tcttcattct agttttcgca gcagggattt taaagtagtt cttattagaa
       61 tagtagagat taattaataa gctatcttcg attgctaaaa agaaaacttc tgaatcccac
      121 accttataaa aatctttgac aaatctattc gaaggatcaa atttaaacca taattgtgtt
      181 tttccttcca tcaacataat gttcacctca aaaagagtat acgaactaat gttctttttg
      241 taaagtagga atatcattga taatatggat ggaacatata tattaaaaag tgttcttttt
      301 gaatgctatt ttgaatgcca ttttcattca tttaacgaaa atctgcgaaa ataaaaaatg
      361 ctcaaaccct tataaaataa ggatttaagc atctagcgaa atctgctgaa atctcacaat
      421 ggagacggcg ggagtcgaac ccgcgtccaa acacatcgcc acttaaaaat ctacgttcat
      481 agtcaactca tttaaggatt cactttacag cttgccgagt gacaggcatt ctgtatcgct
      541 agtctgatgt tctctttttc aacttacaga cggaaagttg aaacgtatcc cactaaagtt
      601 aggaccctta ctcgagcaca tgggcgatgc cgagaggatc tacgctaact gtttttaggc
      661 agctaaagcg taagagttgt tttcgttttt agcagttata tttaactgta acgtttttac
      721 gtagacgtaa cctacgaaac gcaattcaag ctcgactgtg cctgtcgaat ccgtaacgtc
      781 cccgttagct aacaagggtt acgtgtattt ttcatacaaa attagtatag catatattgg
      841 gataaattca ataaaaaagc gaatcatatc ccattattta tataataact gcccctttct
      901 taagaaaaaa taagcgattt tcttaagaaa agaggtagct tcaaaaaaag atcttaaatc
      961 agatcaaaat acttcaatgc gtggacaatt ccgccttctg tatttttctt tgtgataaag
     1021 gtagaaagtt cttttaatcc gtcataggcg ttgcccatag cgattttgtt gtcgcaagct
     1081 tccaacaagg caaaatcatt cggaccatcg ccaaatccaa aagtaggaac tttttccagc
     1141 tgaagttctt tttgcagacg tttgacacct gccccttttg agattccttt cttcactgta
     1201 tcgatcgagt aaggaccatt ccgataaaaa gttagctcag gaaaatgttc gtgatagtat
     1261 tcgtcacctg attgagataa gatcagcaac atatttactg tgttttcttt aaagcctaaa
     1321 ggatcaattt ccggaacatc tgaatgaatg aagtcgtaag cattgatcat tgtttggcta
     1381 tgaccggtac accagatttt ctgatcgtta tagtaagaaa gttcatgacc gttcaactgt
     1441 acatgatcat acattttttg acattcttct gaagaaaatg tttgagaata gatttcttcg
     1501 ccgtctactc gaatgaaaga accattcatg gtgaccgcag aagtaatgcc cgcatcttcc
     1561 atgatagagt ggatttctgc ttctgtacgt cctgtagcga tgacggggag aacattgttt
     1621 tcttttaatg cgttcatagc ttttgccact tcgggtgtga tttttgattt cgcatctagt
     1681 aatgttccat caagatcaaa gaaagtgatt gcacgataat ttgacacaaa taaaactcct
     1741 tttttattgg aataagttta tcttaacaaa gaatgaacaa aagacaaacc tttcgtgaag
     1801 aattcctgaa catattggtt cagtcaacaa tttagagtat actataagaa gagaatttag
     1861 gagggaaaga atgatttttt tcagtattgg tatcttattc ttaataattg gcagtctttt
     1921 tcggattctg ccctcaaaag gaaatctgcc tttttatggg tatcattcgc ctcttgccgc
     1981 aaaaacagac gctcattggc ggctggctca aaagacaagc ggaaactggt tttttcttat
     2041 gggcttactg atggcattga tcggctatta tttaaagaca tctgggcata cgaattattt
     2101 tctgattgaa atgcttctgc tagtatttcc aattatgcct atttttatta tgacagaaaa
     2161 gaaattacag aaatatgacc tggaaactgg agggaacgat aatgaatatt ttaatgattg
     2221 aagataatca atctgtttct gaaatgatgc agatgttttt cttaaatgaa ggttgggaag
     2281 caactttcaa gtatgatgga aaagaagggc tcgatgcctt tttagaaaac ccacaacatt
     2341 gggatatgat tacactagac ctgaatttgc ccacactgga cggtatgcta gtaggaagag
     2401 agatccgcaa agtttcaagt actgtgccga ttatcatgct gacagctaga gattctgaaa
     2461 gcgatcaggt gatcggctta gagatggggg cagatgatta tgtcacaaaa cctttcagtc
     2521 ctctgacgct tattgctcga atgaaagctt tgcatcgccg tagtgagttg gcagaagcaa
     2581 gagaagaagc agtagtttca gatgatcatt ttgatatcga gactagtcat ttcaagatga
     2641 atacgaaaac acgagaagcg tatctggaca accggccaat tgaaggactg acgcctaaag
     2701 agttcgatct attgtttact ttagcaaaaa aaccacgtca agtattctct cgggagcagt
     2761 tgcttgaatt agtctgggat tatcagtact ttggtgatga acggacagtg gacgcccata
     2821 tcaagaaatt acgacaaaaa atcgaaaagg tcggaccaca agtcatccaa actgtttggg
     2881 gagtcggcta caaattcgat gattctggtg ttgcctaatg cgttatttgt atcagcaact
     2941 cttagctttc tgcggaatgg tcgcgttgat cttattgatc gttggagttt cttttacaca
     3001 actgacaaaa caaacgattg aagaaaacaa ttaccagcaa ctgtttggat atgctgaatc
     3061 agttgaaaag acaacgcaaa cctatgccga tacgctcccg cagtttagtc aagatcaggc
     3121 gtttcaaaat gcattgctgc tgacagagca agtactgaca gaacaaaatg tgaactttat
     3181 atttatcgat aaaaacgaac gtgtcattta tccgactaat acagctttac tgaattttac
     3241 cttaacagct gatcaatgga aaaatctgag gaatggacgt caagaaaaat tcacatcgaa
     3301 taaaaatatt ttaggacaag cacaggcgac ctcttacgca cttgtgccat ttaatttgaa
     3361 tcatgaattc tatggagcac ttgtagttag tcaacctgcg cgaaatatcg ataacagcgt
     3421 tcgtccaatt acactgaacc tgttcaaagg atttattttt tccagtatcg ttgcagttat
     3481 tgccagctat gcttttgcag cattccaagt taagcgtatc aatcggttaa ggaatgcgac
     3541 gaaagaagtg acgaatggta attttgatgt acagctcccc gtacatgaca aagatgaatt
     3601 tgatgagtta gcagatgatt tcaataaaat gacgaattca ttgaaagaat ctcaagcaga
     3661 aattgaagaa caagaaaatc gtcgaagaca atttatggca gatgcttctc acgagatgag
     3721 aacacctctt acgacaatca acggacttct ggaagggtta gaatacaatg caatccctga
     3781 aaatcagcga gaaaacgcga ttaaattgat gaaaaatgaa acagagcgtc tgatccgttt
     3841 ggtgaatgaa aacttggatt atgaaaaaat ccgtacgaat caaatcagta tggtcattaa
     3901 aaaattcaat ggaacagaaa cattgaaaaa tattgttgca cagttagaag ctaaagcaga
     3961 agcagcagga gatacattga cattgaaagc cgttgatgat attgatgttt acgctgatta
     4021 tgaccgattt gtccaaatca tggtcaatat tattcaaaac gcgatacagt ttactgaaaa
     4081 cggccaaatc acgattactt tagaaaaagg ctatcttgaa acgatcatca cgattgaaga
     4141 tacgggaatt ggaatgtctg aacaacaaat gaaaagtatc tgggatcgtt attataaagt
     4201 agatccttca agaaaaaata caaaatatgg tgaatcagga ttaggtttac caatcgtgca
     4261 gcaacttgta cgcttgcata aaggaaaatt agaagtagaa agcgaactag gaaaaggaac
     4321 aaaattcgct gttcgtttgc ctgacgtaga aatcaaaaaa gagtaaaaaa caagcggtat
     4381 aaaagatcat gaatcgatct tctataccgc ttgtttttac tataaaatga ttgatttagc
     4441 ccgcgggctc taaacgatca atataaggac tttgagcaat agtagcatca tgagtaaaga
     4501 gtaagatacc ttgattttct tcatgagcta aataagaaag caagtggagt agctcttgga
     4561 tctccaatac actaagttca tcaaatgtat cttcaataac aatattgttt cgcttggaaa
     4621 gcaaggcatg aagtaattgc agctttactt tttcaaaaga cgtcaactca gctgccgcac
     4681 aattaagcaa ggaaggagag atatcaagtt tttcttgata ggccaaacga tcttgtttga
     4741 tttctttttc cggtacatcc aacaggacat ggtctttaag attcagataa ggaaacatcg
     4801 gccaattttt ttggatgatc gcaaaattat ccagttttgc aacaagaacc tcttttttca
     4861 agtgctccaa tattttatgc tgtttttcga gaggacacaa aataacggtc aagtgttcag
     4921 catgaatcaa atattcaggt ttcattacgt ccaggcctcc tactttgcaa atgatggata
     4981 aaaaaagtga aagggaatag actaagaatg agacagcatc cactgagccc aataagagtt
     5041 tgggcaaatc ccttaagtat atctgtgaaa aaaagatcat tttggaaatc gatggtaaaa
     5101 aaagtctgtt gatccatcgg aattgtaagt ccgcttaccg aagtcaagat atcacggata
     5161 tctggcagtt cagtagtctt taagacaaga aaattgatcc tttgaagaag cgcttcataa
     5221 actgactgga agcttacgat ccacaataaa accaagatac aacaaagaaa gagaggaaag
     5281 aacagctgcc agaaaataaa aaggaataat ttggttttag aaagaccagt caggtgccaa
     5341 ttgatcaatt cctgcttgtt ttgcctgact gaatagtaaa agaaaaagat aaaaaggaag
     5401 gcaaatagaa aaaataaact gaatatgcct tttatataaa atcggctagc taattctaaa
     5461 gccggaagaa gctctgtaga tgcagaagcg ccaataaatg aaagccgatc ttggacttga
     5521 ttggctaaag ccgattgcaa atggtaaaga gtcaggcatg ctatcaataa aaaagcagaa
     5581 aagcttgaaa ataaacaata gagtattgtc tgctttttgt aataaattaa tcgagcagta
     5641 gcatagcgga ttattttcat acttttcacc tctataaaaa gtatagaaaa tgaatatgaa
     5701 taaagtatga aattccttta gtgaaatcac gaattaaaac cagaaaatat tttgtaaaaa
     5761 gcaagaggtt gtgaagaagc tgccctattc tattaccgta gatgcaagct tttgaacact
     5821 gtttattcga aaagaggagc agcgacaata attttgtcgc tgctcctttt aaatttattt
     5881 tatcattcgg aagaacttgt ggtcgttccg tgaagttctt ggtacgtttg cgttttataa
     5941 agatcaacag ttgattgtcc gttgtgttca ctaaagacac tagttgactt gtcaccaaga
     6001 gatttttcag cttcttttaa tttctctaag ccattcttgt agtcataatc actggtatca
     6061 attgggtcta atccactatt cgtatagaac cgaagaagat caccattatt gatttggtca
     6121 gaaacagcta actgtttatc aactttttct ttcagtgaat caatttcatt ctgtacttcc
     6181 tcagtaggtt cagtaatagc ttcaccagtt tcgttactat agatcgtacc accgtagtaa
     6241 gtatattttg gtgtaacaaa atcaccatca cggaaagaaa caagctgttc atgatctttc
     6301 gagaatagat cttgtcctaa ctgaatataa ttttttgtat ctacacctag taagtgaagt
     6361 aatgtaggca aggcatcaac ttgtccgccg taagtgtgat tgattccgcc ctgtgtttgt
     6421 ccagggatat ggatcatata agggacacgc tgcatttgtg cattgtcgta gtttgtccaa
     6481 gtagaacttg tttttccaac taattcagct agatttttat ttcttgaatt cgagacaccg
     6541 taatggtcac cgtaaaggac gatgactgaa ttatcataca agccgctttc tttcaaataa
     6601 ttgaagaatt cttgtacggc ggtatctaaa taattggctg tcgcaaagta accgttgatc
     6661 gtttcatcat ttgtattggc taacgggaat cctgcttcgt cattggtgaa ttttgaataa
     6721 ggataatggt tagatacagc aatgaatttt gaataaaatg gttgttgcag acgttccaag
     6781 tattgtacgg attgttggaa aaatggttta tcatgcaacc cgtattggaa cgaattgtca
     6841 tcattaacat cataataaga agaatcaaag aaataatcat atcctaaatt cttgtatgtc
     6901 tcgtttcgat tccagaatgt accagcgttc ccatggaata ccgcactaat gtaaccttgt
     6961 gtttgactta aaatatcagg tgcagcttgg aaagtatttt ttccgcctaa ttgtgtgaac
     7021 aaggagcctt gattcaagcc aaacaatgaa ttttccatca gcgtttccgc atcgcttgtt
     7081 tttcctgctt ttacttgatg gaaaaagttg tcaaaactga acgtgctgtt gctgtggtaa
     7141 agactattga tgaaaggtgt aacttcatgc tggagaccat tctcatctgt caatttataa
     7201 tcgatcagga attgctggaa gctttctaaa tggatataaa tcacattttt tcctctagcg
     7261 agcccgaaca aatcgtcatt tggtgctgca taatgttctt ttacataatt ttctacttct
     7321 ttcatatcat tgggacttgc ttctgcccgc acttggtttg tctggtaagt ttgaacaccg
     7381 tcataaacca tgaaagcatt caagccaaga tatttgacca aataatcacg agagaatgtt
     7441 cgagtcagca attctggacg atcagcttcc gccataaaaa gatttcctga gaaaatcata
     7501 actgctaatg tagagatcgc aaaagccatt cttgctcgga tcgggcgagg gtccaacttg
     7561 attttttttg caatcagcag aacagtcaag ataataaaat cgatccaata gatcacatca
     7621 tatgggcgaa acagtcgaat ggcactttct cccagaccac tcgctacttt cccagcacct
     7681 aaaatcgtgt tgatcgtaat gaagtccgtg aattctcgat aataagtgac attcgaaaaa
     7741 acaagcaatg tcaaaagaaa ataaatgacc atcatcgtga tataagcaac tctagggcgt
     7801 ctgatataaa gagcaattcc aagtaataac aatgtagttg caatagggtt gataaacaag
     7861 ataaagtatt gaatgccact ttcgattccg agatggaaat caactaaata ggcaaaaatc
     7921 gttttcaacc aaagtaaaac gactagtaaa gaaaaaaatc cgagcctctt attcaaaaag
     7981 gcaggtgttt ttatacattt caagataatc ttcctttctg cacttcttaa tcacagaagt
     8041 gtcctgaaac catgttacac agctcactta ttctcattta ttttactagt atgacaatat
     8101 agtgtcaatt gaaaccagaa gtttatgctg tttcattaag gttttcttta agcttcatga
     8161 aaaaatgagc agtaagacaa gtcctatgtt ttttgttata cttgggaaga gaaagctaaa
     8221 gcaggtgaag gaatgaaagt aaaagtaaaa aaaagagcaa gcaatcgatt gaaaaaagga
     8281 tatccactga tccaaaaaga agaccttgct catccccaaa aagaaaccac gcaatgggtg
     8341 gaattagttg attcgcaaaa ccaatttatc gcaaaaggat atctaggaaa gcagaataag
     8401 ggaatcggtt gggtattgag ccagcagaac atcccatttg atcaatcttt ttttgaagaa
     8461 ttttttgtga agtcaaaaga aaaaagaact ttcttttttt cagatgattc tactaccgct
     8521 tttcgtatat tcaatggaga aggagacggg atcggcggtc tgattgttga ttattatgca
     8581 ggttatgctg ttttttcttg gtataacgaa acgttatatg cacatcgtga attattgatt
     8641 caagcttttc gtgaaatcta cccggaaatc ataggaggct atgagaaaat tcgatttgaa
     8701 tcagtaaatc tgcctgagag ccagttcatt tacggaaaag aggcaccgga acccttgatc
     8761 gtaaaagaaa acggagtaaa atttgccgtt tatttaaatg aaggattaat gactgggatc
     8821 tttttagacc aaaaagaagt acggggatca ttagcagaag gtttcgcttc tgggaaaaca
     8881 gttttgaaca tgtttagtta taccggcgcc ttttctgttg ctgccgcaat gggaggggca
     8941 atcgaaacaa caagtgtcga tctagcaaaa cgcagtttaa aaaaaacaca ggaacagttt
     9001 gaagtgaatg gtttggatgt cgatcagcaa aaaatcattg ttatggacgt attcgagtat
     9061 ttcaaatacg ccaaaagaaa acaattttta tatgacatga ttgtattgga tccaccaagt
     9121 tttgccagaa ataagaaaaa agtctttcgc gtagcaaaag attatgggga actggtcaag
     9181 gatagtctgg atattttagc agaagacggg atacttattg cgtctacaaa tgctgcgaat
     9241 gtctcgatag aacaattcca aacaatgatt gaagaggaat tccatgccaa aaatgtttct
     9301 tttgaacaac ttgctttata tcgtctgcca aaagatttcc agacgacgga taccttttta
     9361 gaaggcaatt atctgaaagt gtttgtttat caaattaaaa ataaccatta gaaggagcga
     9421 tgcagaatgg ttcgggtaaa gggattgaat ataggaagcg gtagaccaaa gatttgtgcg
     9481 cctcttatcg gggccgtccg agaggaagta ttacgtgaag cagttcttgc acgtgaagca
     9541 ggggccgatt tagtcgaatg gcgagtcgat cattatcgtg aagttttttc ttttgatgaa
     9601 gtagcagaaa cattggttct tatccatgag atgcttgatg gactgccgtt attatttacg
     9661 tttcgtacct tagctgaagg cggagaacaa gacatatcga tccgtcagta tcgcgacctt
     9721 tatgaacatg tgatacacac aggattagta gatatggtcg atatcgagtt gttcaaagta
     9781 gaaagtctag gaaaaagact gatagaggaa atcaagtctt taaacattcc tttaattatc
     9841 agtagtcatg attttaaaga aacaccagca gaccctgtct tgctttaccg attgaatgtt
     9901 atggaacatt ttggagccga tatcggaaaa ctggcagtaa ctcccaataa tgaacgagat
     9961 gttttgcggt tgatggagtt gactagacgg gcaaatgctt ttgtctccat gcctattatt
    10021 acgatgtcca tgggaaatct tggtaaaatt tctcgtctgg ttggcggaac gacgggttcc
    10081 gttatgacat ttggttcctt aagcagcgat tctacttctg ctccaggaca attaccggtc
    10141 aaagcattga agcaaattat tcaattatta aatgaaccgt tgtagaacaa gtttgaggtg
    10201 atattttttg gcaaagaaaa aaatagtaaa aacgaatgca atccgtatgg tcgaacaaaa
    10261 aaagattccc tatacagagc acgaatatga gtgggacgaa agccacctaa gtgcgtcatc
    10321 ggtcgctgaa cagcttccag aaagccaatc tcgtatattt aaaacactgg ttgctgtggg
    10381 caatgtgacg gggcctcttg ttgctgtgat accgggagaa gccgaattga atctaaaaaa
    10441 attagcaaaa gtttcaggga ataaaaaagt agaaatgctc catttaaaag atttggaagc
    10501 aacgaccgga tacatacgtg gtggctgctc gcctataggt atgaaaaaac tatttcctac
    10561 ttatttagat caaattgcag aaagctatga acaaatcatt gtctcggctg gcagaagagg
    10621 gctacagatg gagttagcac ctcaagatat ctgtgcatta acgagcggac aatttgcaga
    10681 tataaaacaa taaatcatac gtataaaaga aagaaggagg ccgggatgtt gtttgtccag
    10741 tctccttctt tcttttttat acattatgct ctttgcccgg cattcattcc tgctacatgc
    10801 cctgtagcga aagccgctgt gatattaaag ccgccagtat aaccattgac atccagtaat
    10861 tctcccgcaa aatacagacc atcaatgatt ttactctcca atgttttagg ataaatttcc
    10921 tttagagaaa cccctccgcc agttacaaat gatttctcaa taggaaaagt tttgttgatt
    10981 gatagcttaa actctttgca tagttgaaca aaatcttgaa tttgtttttg agaggcttgt
    11041 tgtcctgtca gatgatccat ttcaagccgc tcaagaaaga aaactaacaa tcgctcaggc
    11101 aatataccat gccaagcatt gaccaagttc tttttggttg ctttactttt ttctgtcaat
    11161 atatgaataa gctcttgttt ggtttgtgta gggaaacaat ccagagaaag tgtcactggt
    11221 tctcccgttt tctctaattc tttattgaca aaacttgaac aacgcagtgc agccggacca
    11281 gaaataccga aatgggtgaa aagtaaatcc atcgtatgtt cagtcaatac acgacctttt
    11341 ttatttaaaa cgcgtaaagt gatgtcttgt aaagaaagcc cttgaagtgt tttctcctga
    11401 atatacggtt catccgatat caagggggac tctgtcgcat aaagaggcgt caccgtgtga
    11461 cccactcgct tcacgatctt gtacccatct ccagtagaac cagtagatgg ataagtccgt
    11521 ccaccagttg ttaagataat ggcaggagca tggaactctt cgaattccgt gcgtataccg
    11581 taaattttat gttctttgtg gatcaatttc tctactcgag tagagaatag aagcgtcaca
    11641 tctagttctt tcagacgatt gagcaatgct tcgataatcg tttttgattt atttgttaca
    11701 ggaaacatcc gtccatgatc ctcttctttt aaatgtacgc cttgtgattc aaagaagttc
    11761 atgatatcga aattattcca ttgcgcaaac gtactatata aaaactttcc atttccagga
    11821 atatgtgcaa tcaaatcatc aacaggacga ttgttcgtaa cattgcaccg accaccacct
    11881 gtcatcagta gtttttttcc tgcttttttg tttttttcga tcaagagtac gcgtgcgcct
    11941 tgttcagctg cactgatcgc tgccatcatc ccgcttgttc cagcgccgac tacgatcaca
    12001 tcatacagtt tttccattcc ctcacctcaa ggaaagtgta gcatatctga agaaagaaaa
    12061 cagaaaaaaa tgttttgagc caaaagagaa aatgagctaa aatgagggaa gataagcaaa
    12121 ggagcgtgga acgatgacaa acgcaacaga atatgttcaa gcaattcaag aaaagctaca
    12181 tcaaaaggat caagggcaag aagaattttt acaagcaatc gatgaattca tgcccacggt
    12241 tatgtctttt ttggacactc atcccgaata tatcgaaaag aatatcttag aacttttaac
    12301 ggaaccagaa agagttattc aatttcgagt gccttggcaa gatgatgaag gaaactggcg
    12361 agtaaataga gggtaccgta tccaatacaa ctcagctatc ggcccttata aaggtggatt
    12421 gcgcttccat cctagtgtca atctaagtat cttgaaattt ttggcttttg aacagatttt
    12481 caagaatagt ttaaccggtc tgccaatcgg tggaggaaaa ggcggaagtg acttcgatcc
    12541 taaaggaaaa tctgataatg agatcatgcg tttttgtcaa agtttcatgc tggaattgtc
    12601 aaaacatatc ggcccatcga ttgatgttcc tgcgggagat atcggtgtag gagctagaga
    12661 aatcggctat ttgttcggcg aatataaacg attgaaaaaa tatgatactg gtgtgttgac
    12721 aggtaaacct ttggattttt ggggaagtaa gatacgtacg gaagctactg gttatggatt
    12781 agtgtattat gtcaaacatc tattgaacga agaaaaagat tcatttaatc aaaaaacagt
    12841 ttttgtttcc ggaagcggga atgtagccat ttatgcaatc gaaaaagtgc aagagctagg
    12901 cgggaaagtt gttacatgtt cagattctag cgggtacatc tatgatccag aaggaataga
    12961 tgtgaaacta ttgaaagaag tcaaagaaat caatagacaa cgtttgacgg aatacgcaaa
    13021 ccaacgtcct tctgctattt atcatgctgg agaatctgtt tggacattga aagaaaaagc
    13081 ggatatcgct ttgccatgtg ctactcaaaa tgaaatagac gaaagcttgg ccgaaatctt
    13141 agtagaaaat gggatcaaaa tcgtagcaga aggcgctaat atgccatgta cagtaaaagc
    13201 tgtttctgtt cttcatgaag caggcgtgtg gtattgtcca ggaaaagctg ctaatgctgg
    13261 aggagtagca gtatctgctt tagaaatgag tcagaacgtc cagcgattga cttgggaaag
    13321 agagcaagtg gatgagcagc tggatcaaat catggaaacg atttaccata cgtgtcgcca
    13381 aacagcagcc gagtacggcg acgaaaaaaa tctgcttctt ggagcaaatg ttgctggatt
    13441 tgaaaaagtt gccaaagcaa tggcagcaga aggtttagtt tgaaaaatga aactttcttg
    13501 gaaatattgt cagcattttg tttatttgct tgaaaaataa taaaaaaaaa cgtaaagtat
    13561 tacctgtaga gtaaacctat aaggaggaga acaaatggca cacattcatt ttgactattc
    13621 aaaagtagca ccgtttgtca acgaacaaga gttagggtac atgcaaagcc aagtaacagc
    13681 agcccacaac gaattacggg aaggtactgg cgcaggaagc gacttccgcg gctggatcga
    13741 tttaccaacg aactatgaca aagaagaatt tgcacgtatc aaagaagcag ctaaaaaaat
    13801 ccaatctgat tctgaagtat tagttgttat cggtatcggt ggttcttatt taggcgctcg
    13861 tgcagcgatc gacttcttga atcacacatt cttcaattta ttagatagca acacaagaaa
    13921 agcaccacaa atcttctttg ccggaaattc aatcagctca acatatattg ctgacttgat
    13981 cgaagtaatc ggtgatcgcg acttttcagt aaacgttatt tcaaaatctg gaacaactac
    14041 tgaaccagcg attgcgttcc gtgtattcaa agagcttctt gttaagaaat atggacaaga
    14101 agaagcaaac aaacgtatct acgctacaac agataaagca aaaggtgcag ttaaagtaga
    14161 agcagatgca gaaggttggg aaactttcgt gattcctgat gacatcggcg gacgtttctc
    14221 tgtattaact gctgttggtt tgttaccaat cgctgttagt ggtgcagata tcgatgcatt
    14281 gatgcaaggt gccgctgatg caagcaaagc atactcaagc gacaaactag aagaaaacga
    14341 agcttaccaa tacgcagcaa tgcgcaacat tctttaccgt aaaggcaaag taactgagtt
    14401 gttgatcaac tatgaaccag gaatgcaata cttctcagaa tggtggaaac aattgtatgg
    14461 tgaatctgaa ggaaaagacc aaaaaggcat ctatccttca agcgcaaact tctcaactga
    14521 tttgcactct ttaggacaat tcatccaaga aggacgtcgc aatatttttg aaacagttgt
    14581 gaaggttgaa aaacctcgta aatcaatcac aattcctgaa caagcagaag atttagacgg
    14641 tctaggctac ttgcaaggaa aagaagtgga cttcgtaaat acaaaagcat ttgaaggaac
    14701 attgcttgct catacagacg gtgacgtgcc taacttgcta gtcaaaattc cagaaatgga
    14761 tgcttataca ttgggttata caatgtactt ctttgaaatt gctgtaggta tttcaggtta
    14821 cttgaatgga atcaacccat tcgaccaacc aggtgtagaa gcttacaaga aaaacatgtt
    14881 cgcacttcta ggcaaaccag gctttgaaga tcttgctaaa gaattgaacg aacgcctgta
    14941 agataagggt ttttcgctag atttaaataa tcagtgatag aaacatgttc gctttaaaat
    15001 gaaaactggt acccatttag gtactcaaac atactgcatc gtttattcag aataaggggc
    15061 tgtgacaaga cgtttgtcac agtcccttgt ttgtatagaa atcgattgat tgccttgctc
    15121 tttagtttgt tttaggactt taagaacagt gaggctgact tcgaaggtta attctgtttt
    15181 tttgttttct agaatcagta agcaaaaaag cactcacttc gagtgctttt ttgcgatata
    15241 ttcttagctt aagataggcc taatttttct tttacagatg agggtacctt atcgctggta
    15301 attacttttt tctctatgat ccgcttttcg cttgctttca actgcaagat cgttccttcg
    15361 gggtaagcag aaccattggc agagtcacca gaagtaatga catcgaaatc taactgtctt
    15421 ttttcaccgt tttcagcata agcatctacg ttgtatttaa aacctcttcc aattacttcc
    15481 ccattatctg ctttgatatc agtttctgca ggcattggag ctttgactac cgcataataa
    15541 tctttaccta cataagtaga ctgatagtag tcccaacctt tccatcctat aaaagcaatc
    15601 aatatgataa cgatcaaccc taaaattttt ttcatgaaag atctcctttt ttatttttat
    15661 t
//
LOCUS       DAZKPE010000064        15567 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000064 DAZKPE010000000
VERSION     DAZKPE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.064"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(77..796)
                     /locus_tag="ACG930_002207"
     CDS             complement(77..796)
                     /locus_tag="ACG930_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0519360.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(927..2078)
                     /locus_tag="ACG930_002208"
     CDS             complement(927..2078)
                     /locus_tag="ACG930_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFQ0519361.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(2295..3035)
                     /locus_tag="ACG930_002209"
     CDS             complement(2295..3035)
                     /locus_tag="ACG930_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0519362.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(3039..3362)
                     /gene="rsfS"
                     /locus_tag="ACG930_002210"
     CDS             complement(3039..3362)
                     /gene="rsfS"
                     /locus_tag="ACG930_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFQ0519363.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(3419..4012)
                     /gene="yqeK"
                     /locus_tag="ACG930_002211"
     CDS             complement(3419..4012)
                     /gene="yqeK"
                     /locus_tag="ACG930_002211"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFQ0519364.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(3996..4646)
                     /locus_tag="ACG930_002212"
     CDS             complement(3996..4646)
                     /locus_tag="ACG930_002212"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFQ0519365.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(4656..4967)
                     /gene="yhbY"
                     /locus_tag="ACG930_002213"
     CDS             complement(4656..4967)
                     /gene="yhbY"
                     /locus_tag="ACG930_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFQ0519366.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(4983..6092)
                     /gene="yqeH"
                     /locus_tag="ACG930_002214"
     CDS             complement(4983..6092)
                     /gene="yqeH"
                     /locus_tag="ACG930_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFQ0519367.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(6089..6616)
                     /locus_tag="ACG930_002215"
     CDS             complement(6089..6616)
                     /locus_tag="ACG930_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFQ0519368.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(6796..7581)
                     /locus_tag="ACG930_002216"
     CDS             complement(6796..7581)
                     /locus_tag="ACG930_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFQ0519369.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(7574..8443)
                     /gene="accD"
                     /locus_tag="ACG930_002217"
     CDS             complement(7574..8443)
                     /gene="accD"
                     /locus_tag="ACG930_002217"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFQ0519370.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(8444..9823)
                     /locus_tag="ACG930_002218"
     CDS             complement(8444..9823)
                     /locus_tag="ACG930_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFQ0519371.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(9831..10250)
                     /gene="fabZ"
                     /locus_tag="ACG930_002219"
     CDS             complement(9831..10250)
                     /gene="fabZ"
                     /locus_tag="ACG930_002219"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFQ0519372.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(10275..10751)
                     /gene="accB"
                     /locus_tag="ACG930_002220"
     CDS             complement(10275..10751)
                     /gene="accB"
                     /locus_tag="ACG930_002220"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFQ0519373.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(10754..11989)
                     /gene="fabF"
                     /locus_tag="ACG930_002221"
     CDS             complement(10754..11989)
                     /gene="fabF"
                     /locus_tag="ACG930_002221"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFQ0519374.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(12008..12745)
                     /gene="fabG"
                     /locus_tag="ACG930_002222"
     CDS             complement(12008..12745)
                     /gene="fabG"
                     /locus_tag="ACG930_002222"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFQ0519375.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(12757..13674)
                     /gene="fabD"
                     /locus_tag="ACG930_002223"
     CDS             complement(12757..13674)
                     /gene="fabD"
                     /locus_tag="ACG930_002223"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFQ0519376.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(13781..14005)
                     /locus_tag="ACG930_002224"
     CDS             complement(13781..14005)
                     /locus_tag="ACG930_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFQ0519377.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(14058..15020)
                     /locus_tag="ACG930_002225"
     CDS             complement(14058..15020)
                     /locus_tag="ACG930_002225"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFQ0519378.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(15030..15470)
                     /locus_tag="ACG930_002226"
     CDS             complement(15030..15470)
                     /locus_tag="ACG930_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0519379.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         4079 a         3552 c         2674 g         5262 t
ORIGIN      
        1 aaaagcaaga caatctgtta gtgagattgt cttgcttttc gaaaaagact gaatactttt
       61 cgttaaaact ggttgcttag tcttctaatg ccacattatg gaacacatgc tgtacatctt
      121 ctagatcttc cagtgcatca atcatttttt caaatgtttc ttgatcttct ggagatagtg
      181 ttacctcgtt ttgagggatc atttggatct cagcgattga aaaatcagtg attccttttt
      241 cttttaatgc ttcttgtata ctatggaaat ccgctacttc accgtaaacg atgatttgtc
      301 cttcttcttc cattacatcg cgaacatcga tgtctttttc cattaggtat tcaaggatct
      361 cgtcagcgtc ttctcctgca aaagcaaaga ttgctgtatt gtcaaacatg taagaaaccg
      421 ctccggaaac acccatgttc ccgccatttt tcccaaatgc tgcccgtacg tctgctgctg
      481 ttcgattcac attgttcgtc aatgtatcaa caatcaccat tgagccgctt ggtccaaatc
      541 cttcatagcg caattcagag tatgtttcat ctcctgcacc ttttgctttt tcgattgctc
      601 ggtcaataat atgttttggt acattataag ttttagcgcg atcaatgacg aaacgtagtt
      661 tttggtttgc atgcggatca ggatcacctg attttgctgc cgcgtagatt tcaatcccaa
      721 attttgcata aatccggcta ttattagcat ctttagcagt tttctttgct acgatatttg
      781 cccatttacg tcccatattt tcacttcgct ttctgatttg atagtttcat aacgcaaaaa
      841 cgtcctgttc cattatactt gtgaatcacg attctgtgaa gctttttttc tttcttcctt
      901 cattcttctc atttttagtc aattatctat actcggattg ggatttgccc gaaattctgt
      961 tccggaatat tgcctcccaa ttgatagatt tgatcacttc taactaacag ttccgcttct
     1021 tgtgcctctt tttttccgat tcgggaataa atagaaatct cttttttttc ttttaagaat
     1081 cttcttccag catcggtaaa tccaagtagt cgaagataat ttttattttg ttggacagga
     1141 atctcttgct ttttgatatt cagcaagaca taacaagata atcgttggat ccgtgtccat
     1201 gtatatcttt ttgtttttac ctttgacaca aaatcctcaa aactatcagc agttgcagct
     1261 gctgttttca tgcgcgattc tattccttcg gtcatctgat agatatctgt cagttccagc
     1321 aaagtagaag ataacaaccg ataacgcaaa tacggccaat aagattccca agtctgcagc
     1381 gaacaagttg aaagatcttc ttctgtctga ggcggcacaa gtccagctat tctttttcct
     1441 tcttctaacg catggcgaat ggctgttgca ctggctatcc tctgatctgt gatgattttt
     1501 tcatgatagc ctgcactttt acgtcggatc ggatgtaatt ccatagggtg gacatacttg
     1561 gcattttcct ttgcataact taatcccaag atatgatttg gcgaagaaaa atcaagcgta
     1621 atatcgggat acagactgcg aaaaacctca gtcatttttt gcggataact atacgtttga
     1681 tcagacagtt cttgaaatgc ctcttctatc ctatcttgat tctcttggac aaagcgtccg
     1741 aaactgctgt aatcaaacga agtctcttct tctgttccaa aacacaaact gtcacagtcc
     1801 agtgtttgca agatttttac tgcaccttta gcaaaatagt cagctgactg aaccgcccat
     1861 tcgacgggaa gctccactac taaatccaca ccattttgta aagcttcatt cgcgcgatgc
     1921 catttatcga tgatagccgg ttcgcctctt tgcaaaaaat tcccgctcat tacagcaatg
     1981 acgacctctg ctcctgttat ttttcgtgcc atttccacat gatagcgatg tccattgtga
     2041 aaaggattgt actctacgat aatcccgcag cttttcatgc gcatcctcct tcatagttat
     2101 cgataaaaaa gaaatagaga caagtaaaaa aaggcaaaaa tcggaaaaaa tacccgaact
     2161 atataaacta ttctcgcaaa cacaatactt ctgcgacgaa aagctgcact gcaagagcaa
     2221 tgcctatatc gttcggatat ataatttatg ttgaagattt attcttttct tgttaactcg
     2281 agcaggcaaa accgctagtc tttgtatgct acaaagaacc agcgctttga tttctctgat
     2341 gctgcttcgt ctgtaaaatc agaaaatgct tcgactttcg aaaagccgct gttttccagc
     2401 attcttaaat aactttccaa tggataggta cgctcttgat gtagttcatc ttcacgaata
     2461 aatcgaccag acccttcttg ttcttcaacg aaaaaggtaa gaaaatgttc gatgctgtgt
     2521 ttctcgcttc ctggataact atcccacaaa aaagcaaaat tatccccttg ataatgatag
     2581 ctatattctg gaaaaacctc atctacttga taggtggagt gtacgtcaaa taaaaatcgg
     2641 ccattttctt ctaacgcttg atagacttca tcaaacactt gctgtacctc ttgtctattt
     2701 ttcatatagc acagcgaatc agaaaaacag gtaattgcct gatattgtcc gatttctgat
     2761 aaatcgagca tattgccttc cacaaattgg atcgatgcgt cttcttcata tgctcgctgg
     2821 ctggcaatca tcaacatctc ttctgaaagg tctaaccctg tcactttata tccatctttt
     2881 gcaaaggcaa ccgctaatgc tccagtaccg catgccagtt ccaaaatatt ttttgtgtct
     2941 tcttgtaaat gacgtttcga aaaagctaac cattgctgat aaagtgtttc gtccatcact
     3001 tcatcgtaaa tgaaagcaaa tgtttcataa gccatatgtt aatccaacca ttcactaaga
     3061 tcgactagcg gagcatctga ccatagtttt tccagattat agaaatttcg ttctggcgca
     3121 tggaaaacat gtacgatcac atctccaaga tcgatcaata cccattttcc gccttctttt
     3181 ccttcaatac gttttacttc atatttgttt tcttcttctt tatcaatgat ttcttctgta
     3241 attgcgttga tttgacgttc gctatttgct gaacagatca tgaaataatc tgccaacaag
     3301 gaaacatttc gaacgtctaa agcgataatg tcttctgccc gttttgaatc tgctgcttca
     3361 atcgcaattt ttaattgttc tttactatct atgatgattt cctcctaata tgagcagctt
     3421 atttttttgc tacccagtaa ttatatgttt cgattgtttt tggataaatc tgttgttctt
     3481 gcgcaagcaa atgggccaat gtatgttttg tttcaaatgc tacagcttcg tctagatcag
     3541 cccatgcaat ggctcgtgca tcttgtaccc caggaaaatc tcgacctggt tcaatatagt
     3601 ctgctacata aatgattttg tcaaggagac tcatcttagc agccccagtc gtatgcaccc
     3661 ggattgcatg aagaatctct gcatcggtga ttcctaattc ccgctctaca aacgaagcgc
     3721 caacaagacc atgccagatt gcattattat aattcaataa ctccggatca aaaccgtctc
     3781 ttacgattac cattttgaac tcctcatctg gtcgttcttt tgcataatca tgtgtcaatg
     3841 cagcaatact agctttttca ggagaagcac cgtatttttt ggcaagagcc acggctgttt
     3901 cttctactcc aagcacatgc ttgaagcgtt gttcgctcat tctcatctgt attttttgca
     3961 tcaggttttc tctagaataa gcagtatatt cattactata gtccatattc atacaaccct
     4021 tcattttgaa tataatcaat tactttatct ggaacaaggt agcggataga acagccttct
     4081 ttgatctttt gacgtatttt cgtggaactg atgtcgatct caggtacatc tacccaaatt
     4141 acaggatatg gagtatccgt tgtgtatcct ggtcgacgta tacccacaaa gttgaccata
     4201 gaagtcagct catcgatttt ataccatttt ggcaaatatt ctaccatatc cccaccgata
     4261 ataaagtaat aatctgtatc cggattgttt tgcgtcaatt ccttcatagt atcataggtg
     4321 taacttttcc caccacgagc taattcaatc gtttcaatct gcaaaaaagg attgtcttcc
     4381 accgctaatt ccaacatgtt gagtcgatgt tttgcatcaa tcgtctgttt ctcatcaaca
     4441 tgaggtggct gataagaagg catcaaaaat acgcggtcaa gacctaaatt ccggccagct
     4501 tgttcagcca tcactaaatg tgcaaggtga acgggattga atgttccgcc caagatccct
     4561 acttgctttt tcttctctaa gaattgaggc atttcttcag gaaataattg tgaacgaaca
     4621 aatgtcttag cttgcgtatt catcatggtc actccttata ttgcttttac ttcttttgat
     4681 agcctttgat acttttcttt tgtggaaggt ttgtataata caataacacg tccaatgatt
     4741 tggacgattt cgcaatctat ttctttttct aatacttgag ctgcttcttc tgcaatctca
     4801 tctgtatttt gaagtaacga tactttgatc agttctcttt tttctaaagc ttcttcaatt
     4861 tgaacgatca ttgctgaatt gatcccacct tttccgattt gaaaaatcgg ctgaagatga
     4921 tgcgctttgc tacgtaaaaa acgcttttgt tttcctctta aactcataat tttccttctt
     4981 ccttaaatca atgctttgcg tttcaataca tctacaccct ttggcgccca gcccgcaatt
     5041 actactggcg ctgttacagt gatccagcct agaccggcaa aaacgatgtc tgttttttct
     5101 ttcacagaaa actcaaaacg aacaagctcc ggaaatgcct cgacttcatc aggacgagga
     5161 ggctgtaata atccacctac atgtttttga taaaattcgt ctgctttttc cagtttcgtt
     5221 cgatgaatat ttacatcatt tgacacataa gcaataaatg aagcacgatt gccgctgata
     5281 aaatcaaatc ttgcaagtcc gcccaagaaa agtgtttgcc cttcattcag ctgataaact
     5341 ttaggtttga tttcttttaa cggtgcaatg atccgcaaat cttttttacc taagtagtgc
     5401 gccatttgat ggcgatggat aattcccggt gtatcaatca aaaaatgccc gtcatctaaa
     5461 ggaatctcga ttttatccaa ggtcgttcct ggaaactgcg aagttgtgat tacatcttgt
     5521 actcccgctg tatttttgat gatttgattg ataagcgtcg attttccgac atttgttact
     5581 ccgacgatat agacatcccg tccatcgcgg tattcttcga ttttttctaa tagttccgtc
     5641 atctcatgag atttcttagc actagttaat aatacatcta ctggacgaat tcctgcttcg
     5701 taagcacgtt ccttcatcca ttgtgttaat ttagtttttt tcaatgattt aggtaatata
     5761 tccactttgt tcccaactaa aagtactgga ttgtcaccga caaaacggtg tagtcctggg
     5821 attagtgaac cattgaagtc aaaaatatcc accacattga cgatcaatgc atctttttgc
     5881 cctaattcat tcagtaagcg caaaaagtcg tcatccgtca atgagacatc ttggatctca
     5941 ttataatggc gtaatctgaa acaacgctga caatagactt ccccggaagc taaacctttt
     6001 tccaaagccg tttgcggcgt gtatcctaat tcaccgggtt tgtttgtttg tataacggca
     6061 ccacagccga tacattgtaa ttcttctgtc attcgattcc acctcgccag cccatatcag
     6121 ggtgttttgc taatagatag gccataattc ttttttccca aaaacgatta aattgtgtct
     6181 tccaactatc tgttgcgata atgggtttta caaggatgct acgtatccct gcacgattgg
     6241 ctccacgtat atcagtcata atctgatcgc ctaccattac tatctcatca tctgctaaat
     6301 ccaattgttt ctttgctatg ttgatccctc ttgctaaagg tttcattgct cgtgcaacat
     6361 acaaaagatc aaatttttca atcgctcgcg cgacacgttt tgaattattg tttgaaacaa
     6421 caacaacagg gattcctgca tttttcattt ctaaaatcca agtaagcaac tcttctgttc
     6481 catctggatt attccatgca atcaacgtat tgtctaaatc ggtcaatact gctttgatgc
     6541 ctagattctt taattgggca ggtgtaatct gatagatggc ttctaccatc catgttggtt
     6601 tgtaatttga aaacatgctg tctcctcatc tgcaaaaaat gaaggagcac ataaagtact
     6661 cctcaacccc gtattatact gcatatcagc aaaaaaaact acctctatac tcgttcgtct
     6721 ttcagaaaaa gcatttcttt acaaaatgac caaaaataaa gattgatcac agaaaaattt
     6781 agaaacaaaa aacaactaat attggcggaa cctcttgtat cgtttttcca gtaatttatg
     6841 ctgatctaat cgaacaagtt ccgtcaatct ttcaatcaac gcttttttca taatgtgtgc
     6901 gactttatat cgtggcaact gctcgccgtt gaacgtttca ggaataactc gatcaacgat
     6961 tcctaactcg cgtagttctg gcgcagtaat tttcatcaac tcagctgctt ctgcggcgcg
     7021 actaccgtct ttccacaaaa tcgacgcaaa tccttctgga gaaagcacag cataaatcgt
     7081 ttcttccagc atccagactt catccgctaa acctagagca agggcaccgc cacttccacc
     7141 ttcaccaatg atgatggcga tgatcggtac ctttaaatca gacatttcga gcagatttct
     7201 ggcaatagcc tctccttcgc cgcgctcttc tgctcctaca ccgcaatatg cacctgctgt
     7261 attgatcaag gtaatcaccg gtctattgaa cttttccgct tgtttcatca gtcgtaaagc
     7321 ttttcgatag ccttcaggat ggggagaacc aaaatttctg cggatatttt cctgcagatc
     7381 ccgtcctttt tgaataccga tcactgttac cggtttgcca tctaatcgag cgattccacc
     7441 aacaatcgct tcgtcatctg caaataaacg atcaccatgg cattcctcga aagaatcgaa
     7501 gatctcttca aaaaaatcca agcttgtcca tcgttcttta gctcttgcta actgaacgac
     7561 atcatgtgct gtcttatcca cgatctatcc atcctttctg tgtatgcaat tcaagaagcg
     7621 tatggatttt ctgtttcaat tccatgcggg gaacaatctg atcgacaaaa ccatgagata
     7681 ataagaattc agccttttgg aaatcttctg gaagttcctg cttgatcgtc tgttcgatga
     7741 cgcgtcttcc agcaaaaccg atcaagcttt ggggttctgc tagaataata tcgccttcca
     7801 ttgcaaaact ggcagttact cctccggtcg tcgggtccgt taaaacagtt agataaaaaa
     7861 gaccttcatt gctatgccgt ttgacagcag cagagatttt tgccatctgc attagagaaa
     7921 agattccttc ttgcatccgt gcgccacctg aagctgtgaa caagacgact ggaagacttt
     7981 cctttgttgc tcgttcgaat aatctggtga tcttttctcc gacaatcgtt cccatacttc
     8041 ccatgataaa attaggatcc atcactccaa taatgaaggg aatcccctga atggttgctt
     8101 taccagtgag gactgcttca tgaagtcctg ttttatcttg cattttttta attttttccg
     8161 tatattcggg aaatgctagc ggatctttgg ttacaagatc cgtatcccat tcttcaaaac
     8221 ttttttcatc aataatcaaa gctagacgct gccatgcacc gattcgaaaa gcgtatccgc
     8281 aatgagggca tactttttct tcaccgatgt ctttcgtata aaggatatgt ttgcaatttg
     8341 gacactttgc ccacatgtta tcaggaacag atggcgagtt agcaggtttg ctctctctat
     8401 taggattgat ccgaatatat ttctttttct taaacagagc catctatgcg cctcctatct
     8461 ccgtttctgg tgtccaattc ggtaaaaatt cttcttgtaa aaatgctgtg ctgtaatcac
     8521 ctgctatgac tgcaggatga ctaatcaaat ccatctgaaa ttctgcgttc gtgatgattc
     8581 cttctgtgat aaattcactt aaggctcgct gcatcttcat taatgcttca aaacgcgtat
     8641 ttccatggac gattattttt gcaatcattg aatcataata tggcgggatc gtatatcccg
     8701 ggtaaactgc actgtctact cgcagtccca tcccacctgc tggaagcagt aagttttgga
     8761 tcttccctgg agaaggagca aaatggaaag caggattttc tgcattaatc cggcattcga
     8821 ttgcgtgtcc ttggaatact acttcttctt gacacacatt caaaggctca ccggctgcta
     8881 tctccacctg tttttttact aaatcgattc ctgtgaccat ttctgttact ggatgttcca
     8941 cttggattcg agtattcatt tccatgaaat aaaaatcgcc ttcttcatcc atcagaaact
     9001 cgatcgttcc ggcattttca taattgactg ctttagctgc tcgaacagca gcgtctccta
     9061 gtgcttctct ttttgtttgt gagatcacta cagaaggaga ttcttccagt actttttgat
     9121 tgttgcgttg taaagaacaa tctcgctcgc ctaaatgaat gacatgacca aatcgatcac
     9181 ctaagatctg aacttctata tggcgagcag gataaatgat tttttccaaa tacatatcat
     9241 catttccaaa tgccgctgct gcttcttgct gagctgaaga aaaatgctgt gggagctctt
     9301 cttttgattg aactttccga atgcctttcc cgccaccacc tgcagctgct ttcagcatca
     9361 ctggataacc aattctgtct gctatttcca atgcttcttc tactgtagat aatacaccag
     9421 tacttcctgg aatgactggg acatttgctt cttgcatcaa ttgacgcgca ttgatcttat
     9481 ttcccattgc atcgatcgtt gcacttttag gaccaataaa tgtgatattg cactcttcac
     9541 acatggaggc aaatcggcta ttttcagata aaaaaccaaa tcctggatga attgcttcgg
     9601 cttttgtcac gattgcagcg ctcagtactt cctgaacatt cagatatgaa tcaacggctt
     9661 ttgccgggcc aatgcagatt gcttcatctg ctaactgtgt atgaagtgct tcggcatctg
     9721 cttctgaata tatcgctacg gtttggatcc ctagttcgcg gcatgcacga atgatacgta
     9781 cagcgatttc accgcggtta gctatcaata ctttagaaaa catatttcac ctatccaatc
     9841 ataaaggtta attccgcttc ggctactttt ttaccgtcta ctttagcgat tcctttgcct
     9901 attccggctg aagctttcac tttcaatatc tcaacttcaa ggtataaggt atctcccggt
     9961 gtaactttct tacggaattt tgctttgtcc aatccgccga aataagccgt ctttcccttg
    10021 aattgttcaa gagaaagtaa tgcaactgct cctgcttgag ccattgcttc aacaatcaat
    10081 acccctggca taacaggttc ttctggaaaa tgtccttgaa aaaagggctc attgatcgtt
    10141 acatttttct tagcaacgat ccgttctcct tcaaccattt cttccactcg atcaatcaaa
    10201 agcattggat aacgatgtgg aatgatttct tttatttctt gtatgttcat tgttttccct
    10261 ctttcctgct ttgcttattt ttgctgaatc ctaaagagtg gctgtccata ttcgacaact
    10321 gactcgtttt ctacaaggat ttctgtgatc actccgtcgg cctcactagt tatctcattc
    10381 atcagtttca tcgcttcaat aatgcagata acttctcctt tggcaacttg atcacctact
    10441 tttttgaaag ctggtttgtc gggcgctggt tgcagataaa cgattcccac gattggcgaa
    10501 acaacctcga ttccatcaaa tactgccgat tctttttctt tcattatttc tggagcagtt
    10561 gttgcttgtt cagatatgac attgactggc tccgaaactg gcaacgtttc gtttgtttga
    10621 accatattca tgcctcgact tgttttattt ttattcatat acaattcaaa ttgaccttca
    10681 cgcaaatcga attccgttag cgaggattga tcaaattgac tgactaattc tctgatttca
    10741 ttgatatcca aaattattcc tcccagcgtt tcatgcacag aaccgcatta tgtccgccaa
    10801 accctaatga attactcatt gcataagtaa aacttgcagg tttgctttcg tttttgacaa
    10861 ctgtcaagtc aatctcagga tcttgttttt ctacattgat cgtaggtggg ataaattgat
    10921 gttctaatgc cagcaaagtt gccaaggctt cgatcccgcc ggctgctccc aataaatgtc
    10981 cagtcatcga tttcgtgctg ctgacgtaag tatctctgaa attttcacct aatgcgattt
    11041 ggattgcttt tgcttctgcc tggtcattgg ctggtgtact tgttccgtga gcattgatat
    11101 atccgacttg ttccggctgt acaccagctt cttccatcgc aagcttcatt gctttagatg
    11161 caccagaacc atctggagta ggagctgtca tatggtaagc gtcacagttt gcaccgtatc
    11221 caacgatttc tccatagatt ttggcaccgc gagcttgtgc atgttctaaa gattcaagaa
    11281 ctagaacgcc tgctccttca cccatcacaa aaccattccg attttcgtca aacggaatcg
    11341 aaccacgatt aggatcagtt gattctgaga gtgctgttaa agctgcaaat ccagcaatcc
    11401 ccatctcaca aatcgttgct tctgttcctc cagcaagaat gacatcagaa tagccatgtt
    11461 tgatgttacg gaatgcttcc ccaattgaat tcgttccgct agcacaagct gttacgatag
    11521 ctgtacaaat accttttgca cctacacgca aagcaatatt tccagctgcc atgttggcaa
    11581 tcgccattgg tacgaacatt ggagaaactc gttttgcacc tttttcatgt agacgaataa
    11641 cttggttttc gattgttgga agaccaccga tcccagatcc gatgatgacg ccaaaccggt
    11701 cttgattcat tttttcttta tctaaaccgc tcatctccat tgcttctaaa gcagcgtaga
    11761 ttccatagat cgaaaacata tccattcgtt tgctatcttt tttaataaaa tatttatcgt
    11821 aagggaaatc tttgacttca cccgctaagg taatccctgt ttctgaagca tcaaatttag
    11881 tgatcggtgc gatgccattc gtcccctctt ttaagctatt caaaaagctg tctgcgtcat
    11941 ttccaatagg tgaagtgact ccatagccag taattaccac tcgattcatt tgtttgctct
    12001 ccttttctta tccgtgcatg accaatccgc catcgacatt gatgacttgt ccggtgatat
    12061 atggattttg tgctaagaaa actgctgttt gtgcaatatc ttctacttgt ccgaaacgct
    12121 gcatcggaat ttgcttttcc gcttgttcct tgactttgtc tgctaaaact tccgtcatat
    12181 cagttgtgat gaatcctggc gcaatggcat tacatgtaat gcctctagtt gcagcttctc
    12241 gtgccacaga ttttgttaat cctactacgc cagctttact agctgcataa tttgcttgac
    12301 caatatttcc aatcaaccca gatacactag agagattaat gatggcccct tctcgctgct
    12361 tcatcatttt tttcaatacg tgctgcgtca tattgaaggt tccaatcaaa ttgatatcca
    12421 gacatttttt gaaatcttct gcatccattc gcatcacaag tttgtcattt gtgattccgg
    12481 cattgtttac taacacatgg atcgatccaa gcttttcttc tgcttctttg atcatttgtc
    12541 ccgctttctc ataatcagag atgtcaccgg aaactcctac gcattttaca ccgaatgctt
    12601 cgatttcttc tatcttttct tttggaatct ctccgcgacc attcaaaatg atatttgctc
    12661 cagcttttgc aaaagctaag gccatcgctt tgccgattcc tcttgtacta cctgtgataa
    12721 atacattttt tccttttaca tccataacgt tcctccttat agtattgcta ttgtttcatc
    12781 aaatgtctgc ttattctcaa cacgcagaac tggtattgtt ttatcgattt ttttcataaa
    12841 tccgcttaat acttttccgg ggccgacttc gatgacttgt tcgatgccga ttgtttttaa
    12901 cttatggata ctctcataga aacgaacagg ttgcatgact tgctgttcaa gtagtcccgc
    12961 gattgtttct ttcttcatta tttccgttgt tgtgttgctt atgataggaa aagaaggttc
    13021 agagaattga atctgactta ggtccttcgc cagttttttt gctgccggtt ctaaaatagc
    13081 tgtatgaaaa ggcccgctga catttagagg gatcattctt ttgaaccctt tttcttttaa
    13141 tagtaaaaca gcttcgtcta ctgctttttc ttcgccacca atcacgatct gctgaggtgt
    13201 attataattt gcaggagata cgatgccgta cttgctagct tcatgacagc tttcctcgat
    13261 cgtttcaatc ggcgcattca tcactgcaac cattttcccg cttccagctg gggtagcttc
    13321 tgtcatataa gcgcctcttt ttgctactaa cgcaactgct tcagtgaagg atagcgcatt
    13381 actagctact aatgccgaat attctcctaa actcagtcct aaagctgcat ctgggatgat
    13441 tccatgctcc ttcaataagc gataatacgc gatgctgact gttagaatag ctggctgtgt
    13501 atattgcgtc tgatccaaac gttcattttc tgtaaagcaa agttcagcca tatcgtagcc
    13561 gagaatctca cttgcttcat caaatgtctg ctttacaacg gcttcttcat ataaatcttt
    13621 tcccatacct tgatattgtg caccttggcc actaaataag aatgctgttt tcatgttttt
    13681 ctccaatata tccagaatat atgtttgatt cttcctattc aaaaaggccg agacattcct
    13741 atttcaggaa atgtcccagc ccccaaccta attttaatga ttatgcagtt tgtttttcta
    13801 cgtaagtcac taaatcttga accgttttga ttccgtcttc tgtttcgatt ttcacgtcaa
    13861 attcatcttc aatttcattg atgatttgga ataaatccaa gctgtcagct tctaagtctt
    13921 cttggatgtc agtagtcaat ttgatttctt cagtttcttt tcctaattct tctgcgatga
    13981 tttcttgaat tttttcgaat accataataa tatattcctc cgatattgtt tgctttttat
    14041 ttttataatt taacagtcta caactccatg agaatacttc cccatgttaa acctccgcca
    14101 tagcctgtaa atattacttt ctgctgtttt cctaaggtga tctttccact agaaactgct
    14161 tcatccaata agatagggat gcttgcagca gatgtattcc catatttatc catattggtc
    14221 aggaactttt cttgcggcat ctttactttt cgggcaattt tctcaataat tctgaggttt
    14281 gcctgatgca aaagcagata atcaactggt ttgtctttca tgacttcttg gatattgttt
    14341 gcaacgtctc gtacggcaaa atcaaaaata tctctgccag tcatttgcaa ataatacgaa
    14401 ccttctgaat cttctgaata gaacggattt ttattttgct ggtagccagc ggtcaatgag
    14461 ctacttctgg taccgtcagc tgctaatttt tctttcagca attttttctg tggattcgct
    14521 tctaagagaa tcccacctgc tccatcgcca aacaacacag cagtcgtacg atcagaccaa
    14581 tcgattagct tagatagtgt ttcaccacca atcaccagtc ccttagttga gccgcagcgg
    14641 atcatttttt cagccatgct taacgcataa acaaatcctg agcacgcagc actgatatca
    14701 aaagcgatag catgagttgc tcccaatttc ccttgtactt gtgctgctac agatggtgtc
    14761 gtgtaatcgg gcgacattgt tgctactaaa ataaaatcca aatctttagg gtttagattt
    14821 ttctgtttta tcaatttttc cgccactaaa atgcataaat cagaagtctc ctgatttgtt
    14881 acacatcttc gttcacgaat acccgtcctt gacgaaatcc attcatcaga ggtatccatc
    14941 atcttggaaa gatcattatt agtaataatc ttttcaggaa ggacgctggc tgttgcagta
    15001 atcattccaa attgttccat taaatatcct cacttatagt cttgcaagaa gtcgtgcaag
    15061 tttttcagtg catccagcaa ggcatgctgt tcctccgtag ccattccgtc taagatgttc
    15121 ttgaccattt cacgatgaaa atgctgatgg acccgaaata gtaactttcc ttttttcgtt
    15181 agtcccaact ttacaacgcg gcggtcatct tcactgcgga tacgttcgac atagcctttt
    15241 tttactaact tgttaatagc agtggtcaag gtcccaacag taattgatag ttctttggct
    15301 acttctgaag ttgttttttt cttgtacatc ccgattgcct cgatcgtgtg catctctgtg
    15361 attgacagat ctttgaattg agattttttc agctcagact cttcgattgt caaaatatca
    15421 ttgaagacac taacaagata atcatttact gtttttaaat ctggttccat gttccaccgt
    15481 ccactaatta gtttgattat caaatctttt gatgttcaaa ctatatctta acttttttca
    15541 aaatgcaacc ttaaaagatc atttttt
//
LOCUS       DAZKPE010000065        15439 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000065 DAZKPE010000000
VERSION     DAZKPE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.065"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            163..2223
                     /locus_tag="ACG930_002227"
     CDS             163..2223
                     /locus_tag="ACG930_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFQ0519380.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2306..2875
                     /locus_tag="ACG930_002228"
     CDS             2306..2875
                     /locus_tag="ACG930_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0519381.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3050..3856)
                     /locus_tag="ACG930_002229"
     CDS             complement(3050..3856)
                     /locus_tag="ACG930_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519382.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3994..5508
                     /locus_tag="ACG930_002230"
     CDS             3994..5508
                     /locus_tag="ACG930_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFQ0519383.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5911..6894)
                     /locus_tag="ACG930_002231"
     CDS             complement(5911..6894)
                     /locus_tag="ACG930_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFQ0519384.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6899..7546)
                     /locus_tag="ACG930_002232"
     CDS             complement(6899..7546)
                     /locus_tag="ACG930_002232"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFQ0519385.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7631..8263)
                     /locus_tag="ACG930_002233"
     CDS             complement(7631..8263)
                     /locus_tag="ACG930_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFQ0519386.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8279..8830)
                     /gene="coaC"
                     /locus_tag="ACG930_002234"
     CDS             complement(8279..8830)
                     /gene="coaC"
                     /locus_tag="ACG930_002234"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFQ0519387.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8827..9564)
                     /locus_tag="ACG930_002235"
     CDS             complement(8827..9564)
                     /locus_tag="ACG930_002235"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFQ0519388.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9561..10550)
                     /locus_tag="ACG930_002236"
     CDS             complement(9561..10550)
                     /locus_tag="ACG930_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFQ0519389.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10808..11350
                     /locus_tag="ACG930_002237"
     CDS             10808..11350
                     /locus_tag="ACG930_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFQ0519390.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11367..12452
                     /locus_tag="ACG930_002238"
     CDS             11367..12452
                     /locus_tag="ACG930_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519391.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12464..13270
                     /locus_tag="ACG930_002239"
     CDS             12464..13270
                     /locus_tag="ACG930_002239"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519392.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13271..14098
                     /locus_tag="ACG930_002240"
     CDS             13271..14098
                     /locus_tag="ACG930_002240"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519393.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14095..15168
                     /locus_tag="ACG930_002241"
     CDS             14095..15168
                     /locus_tag="ACG930_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0519394.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
BASE COUNT         4966 a         2788 c         3140 g         4545 t
ORIGIN      
        1 aaaagtacat aagttattat tccgattttc ttgaaacaat aaaaaatcaa aaaaaatact
       61 ctcctaatag tccatcttct tttgatttta tttatataat gaaatcatct tatgaaaatt
      121 actacttcat gtttagacaa gagtagggag gactaagaat aaatgtgttc aaaaagacgt
      181 tcaaaacaac taaataaaca cgcttgtcgt ttagataagg aacggtcgtg ttctgaaaaa
      241 cactacgtta agtttatgat gcgcacgatg ctgatcagtt tatctgtagg tgtctatatg
      301 catgtacccg ttcaggcaac gacacaaacc atcaaggtcg tacgtacctc tgtttctgag
      361 accactgatt cccctatcac tattactcat actttcactg atgcaaatgg aaaacagcta
      421 cttcctgcat tgacttccta taataaagtc agttatcctc caacgataaa ccactactgg
      481 ttaattccta acaaaacatt atggacatcg gaaaccggaa gcagtgtgcc gctttctatc
      541 ttttccgata tgactgatcc tacaaaaggt gatcagttaa aacagatcac tgatattttg
      601 aatcatgctt tgacagatat aaaggacggt ggaagcgcac aagtttctta tgtatatgaa
      661 aaagattatt cacagtttga aagaaagaaa atcgatgttc tggcagggac aaaagtttcg
      721 atatctgatc tggtagaaag gctgaagaac gcagatggaa cacaaggaga tatgtccaaa
      781 gtaatttcaa acaatgggaa tatcgtggat acgactaata caggaacatc tactatttcc
      841 ttgtcctatt ttgatccaat tgctttaaaa acaatgactg catctgctgt gatccatgtt
      901 cgtgctgatc aaacagctat caaaggaaaa gatcttcact taagaacagg agagagttac
      961 gcccctaaag atcttgttga atatgtaaca aaaagcgatg gaacttcagg aaataaagaa
     1021 gaaatcaaaa tgaacgggac agtagatact acaactccgg gagaatatcc cgttgtatta
     1081 acttatatag actcgaaaac atcaaatgtg gcagaaacaa cagctgtagt ttatgtagaa
     1141 gcatctgctg cttcatcgac tgtcatcact cattttatag atagtcaaac aaataaagaa
     1201 cttcaagcag aaacacatat gagtagtgta aatcgtattc ctgatttgcg cctacctgct
     1261 gaattttctg atcgagtgcc aaatatagat ttatcgactt atgaacaaaa tgggaaagtc
     1321 acttctattt ctgattggat gcaagcaaac ggattagaca gaaaaagtca ctggtcggag
     1381 atccttgaag tacttcactc agaactgatg aataatagga agcaatcagg aggggaaatt
     1441 acctttactt atgtttatat accagacaat cgttcattag aaggtcatga tcttattgtt
     1501 catccaaacg aaaaaataaa caaagaagag ttgatccaat cagcaacaaa ttccttaggt
     1561 aaacccgtac cgttaaagga tgtatcggtt acaatcaatg aagtaccatt ggaggatggt
     1621 tatttgacca aacaaacagg tgattttacg attatgtata gttatcatga cccgtattca
     1681 ctccaagaac tccatgctca gtcactatta catgttttac cattaaacaa acagatagat
     1741 caaaaagaac aaaaaagaca agaagaaagc ttgtcagaaa aaaaacaaca aatggctcat
     1801 gcagtttctc caacagggaa agtaaaacaa acaagaagcc tagagttagc aagaatatct
     1861 agaaaaatct cagaatctaa taaaacgata aggcaagaag ctcatttggc cccacaagtt
     1921 tctggattgg aaaatgaaat tttagagcct aaaataaaac aacaatcaga aaaagaattt
     1981 gttgctaaac agtcggaaga tcagaaggaa tcagatgacc agaaggaaac gaagaaaaaa
     2041 cgcttgtcaa ctattgattc caccgatgag catctgcagc cgcaagtacc acttcctagt
     2101 ccgggaacac ccgcacctgg tggaggtatt ccttcttctg ctttaggaga tttcatgcga
     2161 ggtatggcag gaacatgggt atacgctaat cgaaatgaat ttgacgcaga tgactggttc
     2221 tgatttatat ctctatctgt tatagtcaaa taagtagctg agtcatatgt tatttggcat
     2281 aatggagacg aggagggata gaaaaatgtt agataaaacg ttaccttacg cagaaatctg
     2341 gatgacaaga ccacttcaac aaaatgttcc aatcacgcct ttagcggaag gttttgaatt
     2401 tcgattttat caaaaagaag atgaatctgc ttgggcggag attgagactt ccgttgggga
     2461 atttcaaacg acagatgaag cacttgagta ttttcaacaa aactttgctc cttatcctga
     2521 agaacttgaa agaaggatgt tttttgtaga gacaaaaaaa ggagaaaaag tagcaacctg
     2581 taccgcttgg cgaaaaaaat caagagagca agtgtatccg gtttttcatt ggttagcagt
     2641 gaaaccagat taccaaggaa aagggctcgc aaaagcattg actgccagag tcttgcaaga
     2701 atttcctacc ctccatacgg acggaccaat ctatcttcac acacagacat ggagccatca
     2761 ggcgattgct ctttataaaa aaatgggttt tacttttatt gctgaaaatc tagacggcac
     2821 acctaatcca gattatgaaa aagttatgca ggttttaagt aaattagata aataacgaaa
     2881 tggtgaaata agtcctcagt attgggataa aaaacgaaat agtcattcct catatcttac
     2941 ttttttgagt taatactatc ggataactaa tggcatgcca tacattcaaa aaagaagggg
     3001 cagtgacaaa agtattgtca ctgccccttc tcttgttttt tagcatgttt tatcgtttga
     3061 tttttttagg aataaaattc ttgatgaacg taaatttttg gtaatcgttt cgactataga
     3121 ggtaaccaaa tacactgaaa acaactgctc caataaaatt aacaaataaa tccttcatag
     3181 tatccatgat tcccacgtct aagtaaccat tttggatgat tgttttatct gttttaccat
     3241 ctgcattttg actttcaatg attgtccgag tgatatctgg aacatgatag acagtgtttc
     3301 cgtctttact taactccaca ctattgattt gctggatgat cgtatctttt tgcatatcga
     3361 attgcagtaa tttatctgct gaaaattcca caaactccca cataacacca actgtcatcg
     3421 aaaaacagaa ggaaacaact gctagtaata aaggagtcaa gttcatggtt tttgtatttt
     3481 tattgagcaa ataaacaagg gaaaagccga cacccccagc taaaaatccg ctgaatgcat
     3541 gtagaaaagt atcccacatt gaaaaatagc cataaaaatc acttaactct cctaaaactg
     3601 ttgaactaaa aataaaagat aacaaaatga tttctagcat atttggaatc tgtatcttta
     3661 atatcttttc cagaaaataa gggatttcaa ataaaattaa tgtcagtaat aaaagcattg
     3721 tatttcccca gtgttggttc cagacctgat ccactagcat aataacgacg atgatacgta
     3781 ataaaatata gattccgttt gtgattctac ctgcagtttt tgtactgttc gtaaaaaagg
     3841 ttttcaaatg attcataaaa taactccttc atgtatatcc ttaattatac taagaagcgt
     3901 gtgtttacca aagctatatg acttaaagaa aaacagagtt gatattgtga aaaaaatcac
     3961 ttaatatagt ataaggagaa aagggggata caaatgaaaa aattagttgc tggtttatta
     4021 acagccgttg cacttcttgc tatgagcgca tgcggcgcag atcagaaaaa tacagcgcag
     4081 acaagttcta gtacgaagga atctgccgaa gtatcatcag gcgcttctga acaagtatat
     4141 acagatccaa aagaaatgaa agaatcttat gatgtcgtga ttattggagc tggtggtgca
     4201 gggatggcag cagctatcga agcaaaagat gctgggttga atccagtaat tttggaaaag
     4261 atgcctgttg ccggaggaaa cacatctaaa tcatcaagcg gtatgaatgc ttcagaaaca
     4321 aaatttcaaa aagaagaagg aatcaaagac tcgaatgatg ccttctatga agaaacgcta
     4381 aaaggtggtg gaggaacgaa tgataaagaa atgcttcgat actttgtcga tcactctgct
     4441 gatgcggtcg attggctaga tcaaaacggt atcaaactgg acaacttaac gatcactgga
     4501 gggatgagtg aaaagaggac acatcgtccg tctgatggct cggctattgg tggatactta
     4561 gtggaggggt tattgaataa cgtccatgag cgggaaatcc ctatttttgt caacgcagat
     4621 gtgacagaca ttaagaaaaa tggggaaacg gtcaatgaag tgactgtaca tgttcaagga
     4681 gaagaaccaa aagaggtcac cggaaaagca atcgtagtta ccacaggcgg ttttggtgcc
     4741 agcaaagaat ttattgaaaa atatcgtccc gatttagctg attatattac gacaaatcaa
     4801 gaaggatcaa ctggagatgg tatcaccatg attgaaaaat taggtggaca aaccgttgat
     4861 atggataaaa tacaaattca tccaactgtg cagcaggatg agggggtctt gattggtgag
     4921 gttgttcgcg gagaaggagc aatcttggtc gatcaagagg ggaaaagatt tgtcaatgaa
     4981 atggatacaa gggataaagt atctgcagca attacagcat tgcctgaaaa atcagcttat
     5041 ttgatttttg accaaggcgt gcgtgatcgt gccacagcta ttgaatttta tgaccaaaaa
     5101 ggatatgtca caactggaaa gacaatggaa gaattagcag aaaaaatcga tttaccaaaa
     5161 gaaacactag caaaaacagt tgatggatgg aatacggatg ttgcggagaa aaaagatgct
     5221 caattcaacc gtgccacagc catggaacat gacttatcgt ctccgaatta ttatgcgatc
     5281 aaaatcgcac caggaatcca ttacacgatg ggcggtgtga aaatcaatac gaacactgaa
     5341 gtattagata aagaaaacca gccaattagg gggttatatg ctgctggtga agtcacaggt
     5401 ggcttacatg gaaacaaccg gatcggtgga aattcagttg cggagatcat tatttttggg
     5461 cgacaagcgg gcatacaagc agctcgattt gcttcggaaa atgaatgaaa tagaacgtaa
     5521 ataaaaagag gttgtgaaat cagcgttttg agctaatacc gagggtcagc tgattgaaca
     5581 ctgtttagtg aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaagt
     5641 aaaaacagct tcttatgttt ttaacttggt tggacttatt accgcagatg caagcttttg
     5701 aacaccgttt attcggaaaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc
     5761 tctaaacacg tataaacggc ggaagcagaa gaaattcctt cggaaataag ctgaaattca
     5821 caaaaatttg aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct
     5881 gtcccagcct cttttttgat cagcatgatt ttattcagtt atcttcaaaa tgatttttcc
     5941 gatgtttttg tttgcttcca tatattcatg cgcttgtttg actgcgctga attggaatgt
     6001 acggtcaatg attggccgaa tcttgccatt ttctagaaaa ggcccagctt tttgcataaa
     6061 agtttgtgcg agctctgctt tatactgatc acttctaggt gtcaataatg taccaagcag
     6121 ttggacacgt ttcccaatca atacaccaag gtctatctca ggcacgatgg tcccacctag
     6181 cataccaatc aagacccaac gtccatcaac ggctatagaa gctaaattct tttcccagta
     6241 agaagcgccg atgaaatcca aaataacatc gactccccga ccttcagtga tttttcgtac
     6301 ctcttcttga aagtcttgtt ttttatagtt gatcaattca tctgcaccaa gttctttaca
     6361 aaaggcgagt ttttcttctg atcctgcagt aacgatgatt ttcgcgtgag aaagctgtct
     6421 agctaattgg atcgctgctg ttcccacacc acttgctcct gcatggatca agacagtttc
     6481 gccttcttgt aattttccaa gccagtaaag tgtttgataa gcagtcaaaa aaacttctga
     6541 gattccagca gcagaaacat agtctagcgt atcagggaga aggattgcac gatcggcagg
     6601 catcacagca tattcggcat aaccacctag attgactaat ccgtatactt ttgtcccagg
     6661 agtaaaagtg gagatatcac ttttattctc aactacctct ccagctactt cgactcccaa
     6721 aatagggtag ggaggtttca aagagactga ttctcttttc ataatatctg ttcgattgac
     6781 agctgctgta tggactttga tcagtaattc gccttgtttt ggtttaggaa caggcacttc
     6841 aatttgttct aatacatcta cagaaccagg atgcttgatt gaaatggcac gcatggatct
     6901 attcctcctt tgcccattct tggaatgctg tattcaactc tttgctacct tcagaaagta
     6961 ctagagtcgt acgagaaata tccgtttctt ccactagagc ggcaagtaca gcagcaactg
     7021 tagagcgagt gatcgttttt gatgccttct cattaggctt agttaattga atggaagtaa
     7081 cttcttcatc gttagtcaat gtgactggtt gaagaatgac aaaatctaag ttagttcgtt
     7141 tcagccattc atctgcataa tgtttagtaa tataataatc tgtcatggac tcaggccatt
     7201 ttgctggttc atctgcataa acagcactga ccatcagata gcgagagaca tgcgcatttt
     7261 cagctgcgat cactgttttg attgcgccat ccaagtctac ttgcagaaga ttctttcctt
     7321 gagagccggc agcaaaaatc aatacatcga tgcctttgaa tgcttcggtc attttttcca
     7381 cggaccaagt taaatcaaaa gagacatacg aaacattctc tttttttact aatgtttggg
     7441 aagcaacatc tctcacccct gcaaaaattt catgggaact tggagctaaa tcttttatca
     7501 ggtgtcggcc aatttgtccg tttgcaccta caacaaaaat tttcatttgg atcatccttt
     7561 cgacgtcaaa tctttccatt caatagtaac accaaaagag aaaaaaatca gagatcggct
     7621 acgatgacta tcagttagta agagaagggt gcttgaagta tcttaacaag acattgcata
     7681 ctgctgcagt cgcaagacct gcgacgattc cttcaggtat accacttgta aaaataaccg
     7741 ctagaatagc tgaataaaca gcatttaaat ttgttccgat gactttggca taatcttgct
     7801 ggaataaaaa gtagatcata ttcatcacta aaatcgtatt ggtcaatgaa ccggaaagtc
     7861 cagctaagaa taaagaaacg gaatctgctt tttgtttcat tagtttgcgc agacctttat
     7921 aaacgaaata aggaaccacc ccaatcaaga tgcgaggaat aaacgcgatc agcaaggctt
     7981 tccagcttcc atgttctgtt ccgatgactg ggataaacgg agaaaagaca aaagacaaag
     8041 gtgtttggat aactgtgcta cggatcatgc tgatcagtcc aaatgtaccg ccaagaaaag
     8101 cacctagtct tggtcctaaa acgatcgaag caatgattac aggaatatgc atggttgttg
     8161 cattgattgg accgataggg ataaaaccta aaggcgtaac agctaataaa atcaaaatag
     8221 ctaaaaacat cgcagttaat gtaaagtttt ttgtattttt cataagtact ccttttttct
     8281 aagcatttct ttcattaaga gtcagcatga cctgttcgat gatcgtctga atatcagcta
     8341 aggcaccttt tccaaaatct ccacaagcta aaagagattc tcttggttca atttcctgat
     8401 agccgacaga tctcaatgtt tccagattac gctgagtgat cgggttttga tacatattcg
     8461 tgttcatggc aggggcaatc aattttggtg ttcccactgg aagcgccatt gcgactgttg
     8521 aaagaagatc gtctgcaatg ccgtttgcta gcttgccgat aatgtttgct gtagcaggcg
     8581 cgatgagaaa caagtcagct tgttttgcta gttcgatatg attgattacc tgcggatttg
     8641 attcttgcat gacgtctgta tggactgcgc gcttcgacag agattgcaag gttaatggcg
     8701 tgataaaatg tgtgctgctt ttagacataa tcacatctac ctgggcacct aatttgacga
     8761 attgacttgt aagatcagcg cttttgtaag cagaaatact tccagtaacg cctagtaaga
     8821 tctttttcat tttgattcct ccagtctaat tttctcagta atcaatgcag caatctcaga
     8881 tttactttga gcttcttcca ctgttccatc tttagataag agatagccgt ggtgtgtctc
     8941 gccatggatt tccgtcaaat catttgcgaa aataaaatca gttttgttat ttatcagact
     9001 attttttgcg actgccagaa gagattcctt tggtacatct actaatagtt tgaaaccaat
     9061 gatttttgct tttggctgcc attcacgtag ataagaaatg atttttggtg ttttcttcaa
     9121 aacgagcaca agatgctcgg tgttagaaga gatctttgaa acagtggtat ctgtctgttc
     9181 attttccgca aaccaattgt ccagttcttc ttgcgttgaa gaagtgggta ggttttttgc
     9241 cagctgttct tctgaaaaac taaaagcagg agtaaaatca ctgactgcca tactgtggat
     9301 aatcgcatcg tagtgttctt ttttcgttag ttcttctaat tgtaaaaata agtccagtgc
     9361 agattcgatc gtataaatcg ttatattgga gtgtcttttc ggtttcagtg cttgtttcgt
     9421 agtcacgtaa tcgattgtgg tatccggatt ggcagctaaa taatcagcta atgcttgccc
     9481 taatcgtcct gtcgaatgat ttgtaatagc acgtacttga tcgatttttt cagtcgttcc
     9541 tccagctgtg attagaatct tcatttatgg tcacctacat ttactagtgt tcttccttgg
     9601 tgtgttccag caagtagttt agatgctgtt tcaggcaatt gatccagagt aatctcttgg
     9661 acgaccagtt catctgcaat ctgcaaatcc gccatctgtt gccataaaga aagacgttga
     9721 tctattggta cattgacaga atcaattcca atcaactgga tgtttcgcag aataaaaggc
     9781 aagacagtcg cgtttagttt gattccccca gcattgccac ataaagctac tgcaccgtta
     9841 taagagatca atggaagaag actgcttagc tgctcgccac ctactgtgtc gatgacatag
     9901 tcgatttgct gttttcctaa agcttttgtt gtctctggca gaaattcatc aggtcgtacg
     9961 acttgcaaag cacctagact ttttagccat gtgacagact cttcttttct ggaaaaggta
    10021 atgattgact ggaatcctag tttatgtaac agggctatcg ctgtactgcc tacaccgcca
    10081 gaagcaccag taacgacaac ttttttatcg gaggtcatac cttgacggat taaagcgttc
    10141 acacacaaca tagcagtaaa ccctgctgta ccaaggatca tcgcttgacg cagcgtcata
    10201 ttttttggta gaggaactaa ccagtctcct ggtacttttt gatattggct ataaccgcct
    10261 ggatgggtga cgccaagccc aaaaccagta gcaagtacaa gatcttcttt tgaaaaacgt
    10321 ggattgttac tttggacgac agttccggat aaatcaatcc ctggagtcat cggatatgtt
    10381 cgtatcacct gaccagactc gctcattgcc aatgcatctt tataattgac atcagaatag
    10441 gcaattttta ccaagacttc attttcagcc aactcagtaa atggcagatc actgattgct
    10501 gtatggaaaa caggttcctt tattacctga aaagatcgaa aagcgttcat tcgtgagaca
    10561 ctccttttaa aattttcttt tatcatacca taaagcctac tcttttattc ttgttcttcc
    10621 gtaaatttag acaaaaatta ggtgaaaaat aaagaatcaa acaactagaa tttattccaa
    10681 aagataaaga aatattcagc aaaaaaaatt ttacaaaggg ttgccttttt caataaattt
    10741 cgtatactaa tacgagtggt agtaaacagg aagtttacta ttagaaaact tcgattcgga
    10801 ggaaattatg gaaattggtg agaagttaag aaatttgcgc atccaaaaga atttgacaca
    10861 agaagaacta ggcgaacgca cagatttgtc aaaagggtat atttcccagt tggaacgaga
    10921 tttaagttca ccatcaatgg aaacattctt ttctattctt gaagtcttag gtgtgactcc
    10981 agaagaattt tttcatcaag aagcagcgaa tctgcaagtg gtttattcaa aagaagatca
    11041 tacggtttat ttcgatgaag aaaacgggta tgaattggaa tggctcgtgg ctgattcgaa
    11101 tgaaaaagaa atggagcctg tcttgctgac ttttgaaggt gcaggagaat ataagacgtt
    11161 tgaaccttca ttatctgaaa cgtttatttt tgtattagaa ggggaattag agttaagctt
    11221 aggagagacg gtctatgtgg caaaagcagg acagtcgatc tattatcaag cgacaaaaca
    11281 acatcaatta aggaatcatc tcaaaaaacg aacaaaagta ttgattgttg caacgcaatc
    11341 atatttgtaa tatagggggt aaaaacgtgg ggaaaccaat catttcattt gatcaagtag
    11401 tgaaacgcta tgatgatgaa acagtattaa aaaaagtaag ttttgagatc gaacaaggaa
    11461 aattttatac actgcttggt ccttccggct gtggtaaaac aacgatccta cgtattatag
    11521 ctggattcac cgaagctaca gaaggggaca tctattttga agggaaacgg ttgaatgatt
    11581 tgccagctaa taagcgacaa gtaaatacag tcttccaaga ttatgcactt tttcctcata
    11641 tgaatgtttt tgataacgtt gcttttggat tgaagatcaa gaaaatgtcc aaatcagata
    11701 tcgaaaagaa ggtaaaagat gctttgcgta tggtccagct tcctggatac gaaaaacggg
    11761 agattagtga aatgtctggt ggtcaaagac agcgtgtagc gattgcacga gcaattgtaa
    11821 atgaaccgaa agtattgcta ttagatgaac cgttatcggc gcttgatttg aaactacgta
    11881 cagatatgca gtatgaactg cgggatctgc aacaacgatt aggaatcacg tttatttttg
    11941 ttactcatga ccaagaagaa gcgttggcaa tgagtgatga gatttttgtc atgaataaag
    12001 ggaaaatcgt ccaaagtggt acacccgtag atatttatga tgagccaatc aatcatttcg
    12061 ttgctgattt tgttggggag agcaatatcg tggacggtgt aatgatcgaa gataatctag
    12121 ttgagtttgt tggtaagcaa tttgaatgtg tcgatggcgg gatgcgtcta aatgaaccag
    12181 ttgaagttgt tttacgccca gaggatttga cgatcacgac accagataaa ggaaaactag
    12241 tcgtaacggt cgatactcag ctgtttcgtg gtgtccatta tgaaatcatc tgttatgatg
    12301 aacagcaaaa tgaatggatg gtccattcaa cgaaaaaagc taaagaagga agcaaagtag
    12361 gattggcctt tgagccagaa gatatccatg tcatgcgttt caacgagtct gaagaagaat
    12421 tcgatgcacg tcttgacagc tacgaagaat aggggggaca agaatgaaaa caatgcgcag
    12481 gatctattcc gtcccttata ttttgtggct cggtttattc gtgatcgcgc ctgtattaat
    12541 gatcatttat caatcttttt ttgatatgaa tgggcaattc acgctgaata attatctatc
    12601 ttattttacg tcggggacat cgctttctat gacgatcaat tctgtatggt atgcattttt
    12661 gatcacgttt ttcacgctga tcatcagtta cccgactgct tattttttaa caaaactgaa
    12721 gcacaagcaa ttatggctga tgctgattat tttgcctaca tgggtgaatc tgctgcttaa
    12781 agcttacgca tttattggga ttttcagtgt gcacggcagc gtgaatcatt tctttgattt
    12841 tatcgggatc gggccgaaac agatattatt cacagacttc agttttctgt tcgtggcaac
    12901 gtatatcgag attccattta tgattatgcc aattttcaat gcattggaag agatgaatcc
    12961 ttctttgatc agtgctagta gagatttagg cgcgaatagc tttgagacct tccgacgagt
    13021 gatttttccg ttatcattaa atggtgtgaa aagtggtgtc caagcagtat ttattccttc
    13081 tctttcttta ttcatgctga ctcgtctgat tggcggaaat cgggtgatca ctttaggaac
    13141 ggctatcgaa cagcatttct tggttacaca aaactggggg atgggttcta caatcggtgt
    13201 gattttaatc attgctatgt tcatcgtgat gctcctgaca ggcgagaaga aaaaaggagg
    13261 tcgctcataa atgaaaaaat ttaaatggtc gtatctttat ttagggatcg tctttttatt
    13321 cttatatgca ccgatcttct atctgatttt ttattccttc aatgaaggag gaacgatgaa
    13381 cagctttaca ggatttactt gggaaaatta tgaagctgtt tttgaagata cacgtttgat
    13441 cattatcgta ttgaatacgt tcatgctggc tttcttatct gcattgatcg ccacgatcat
    13501 cgggacattt ggggctatgg gaatctatta cacgaaaaaa cgacgtgcac ggacagcgtt
    13561 gttgagcatg aataacatct tattagtctc tcctgatgtt attatcggtg ctagtttctt
    13621 gattttcttt acactactag gattcggatt aggttttcag agtgtattgc tttcccatat
    13681 tgctttcagc attccaatcg tcgtcttgat ggtcttgcca aaattgcagg aaatgaacga
    13741 ttcaatggtc gatgcggcta gagaccttgg tgctaataat ttccaagtag tcaaaaatat
    13801 cattttgcct tatctttctc caggaatcat agctggatat tttatggcat ttacctattc
    13861 tcttgatgat tttgcggtta catttttcgt cacaggaaat ggctttacga cgctctcagt
    13921 agagatctat tctcgtgcaa gacaaggaat cagtttagaa atcaatgcgc taagtgcgtt
    13981 agttttcttg ttctccatga tattggtcat tggatactac tttattagta aagaaaaccg
    14041 tccaaaacgg ctgaagaaaa acagaagagt acgcgagggg gtggcacggc tgcgatgaaa
    14101 aaattacaat ctctgttttt aggtattctc atcattattg cggtgctgct gcttggtgtt
    14161 cgtcaacttg aaaaaacaag tggcatgagt ggagcaaagg tacttaccat ctataactgg
    14221 ggagattata tcgatcctag tttgatcacg aaatttgaaa aagaatatgg atacaaagtg
    14281 aattatgaaa catttgattc taatgaagcg atgttcacaa aaatccagca aggtgggaca
    14341 aactacgaca tcgctatacc aagtgaatat atgatccaaa aaatgatcaa agaaaaacta
    14401 gtacttccat tagatcattc gaagatcaaa ggattaaata atattgatcc acgattttta
    14461 gacttggatt ttgatccaga taatcagtat tcgattccat atttttgggg aactttaggg
    14521 atcgtatata acgataaatt ctttgatgca aatcaaatta agcattggga tgatttgtgg
    14581 aagccggaat taaaagacag tttgatgctg attgacggtg cacgagaagt tatggggctt
    14641 tctttgaata gtttaggcta ttctttgaat agtaagaata tggcacagct gacagaagca
    14701 gcaaataaat tgaatcattt aacaccaaat gtcaaagcaa tcgtggcaga tgagatcaaa
    14761 atgtatatga tcaatgaaga agcctccgtg gcagtgacat tttctggcga agctgccgat
    14821 atgatgtggg aaaatgaaca tttacattat gtgatcccac cagaaggatc caatctttgg
    14881 tttgataata tcgttatgcc aaaaaccgtg aaaaataaag aaggtgccta tgatttcatc
    14941 aactttatgc tagaaccgga aaatgcggca caaaatgcag agtatattgg ttattctaca
    15001 ccaaatgaag aagcaaaagc gttattgcca aaagacattt cgtcggacga acaattctat
    15061 ccatctgatg acacgatctc ccatcttgaa gtctacaaag atctaggatc gaaataccta
    15121 ggcatctata atgacctatt cttagaattc aagatgtata ggagataatg gcaaaactca
    15181 gtaagaatgg ggacttatca acgttctaaa gagctaaaaa tcgtcctttt tctatctgag
    15241 ttttccaatc ttctaccaaa agcggatgaa acgccgcttt ttttgtgtta ttttattttt
    15301 tctaccacgt ttttctacca gagaaaagtg gacaaaacca ttgtaaaata gggcccgaga
    15361 cgggctagta aatctaagat tgaaaaagtt acagaaggat aaagtaattg gaaactatgc
    15421 aaatatactt aacccttct
//
LOCUS       DAZKPE010000066        15193 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000066 DAZKPE010000000
VERSION     DAZKPE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.066"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(797..1138)
                     /locus_tag="ACG930_002242"
     CDS             complement(797..1138)
                     /locus_tag="ACG930_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0519395.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1138..1368)
                     /locus_tag="ACG930_002243"
     CDS             complement(1138..1368)
                     /locus_tag="ACG930_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0519396.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1655..1993
                     /locus_tag="ACG930_002244"
     CDS             1655..1993
                     /locus_tag="ACG930_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519397.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(2198..2760)
                     /locus_tag="ACG930_002245"
                     /pseudo
     CDS             complement(2198..2760)
                     /locus_tag="ACG930_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(3492..4073)
                     /locus_tag="ACG930_002246"
     CDS             complement(3492..4073)
                     /locus_tag="ACG930_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0519398.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(4256..4882)
                     /locus_tag="ACG930_002247"
     CDS             complement(4256..4882)
                     /locus_tag="ACG930_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFQ0519399.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4904..6235)
                     /locus_tag="ACG930_002248"
     CDS             complement(4904..6235)
                     /locus_tag="ACG930_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFQ0519400.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(6390..6791)
                     /locus_tag="ACG930_002249"
     CDS             complement(6390..6791)
                     /locus_tag="ACG930_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFQ0519401.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(6877..7083)
                     /locus_tag="ACG930_002250"
     CDS             complement(6877..7083)
                     /locus_tag="ACG930_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519402.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(7178..8680)
                     /locus_tag="ACG930_002251"
     CDS             complement(7178..8680)
                     /locus_tag="ACG930_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFQ0519403.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(8698..9153)
                     /gene="argR"
                     /locus_tag="ACG930_002252"
     CDS             complement(8698..9153)
                     /gene="argR"
                     /locus_tag="ACG930_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0519404.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(9251..9868)
                     /locus_tag="ACG930_002253"
     CDS             complement(9251..9868)
                     /locus_tag="ACG930_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0519405.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            10089..11462
                     /locus_tag="ACG930_002254"
     CDS             10089..11462
                     /locus_tag="ACG930_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0519406.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFVGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            11537..12649
                     /locus_tag="ACG930_002255"
     CDS             11537..12649
                     /locus_tag="ACG930_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0519407.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(12721..14358)
                     /locus_tag="ACG930_002256"
     CDS             complement(12721..14358)
                     /locus_tag="ACG930_002256"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFQ0519408.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(14526..15134)
                     /locus_tag="ACG930_002257"
     CDS             complement(14526..15134)
                     /locus_tag="ACG930_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0519409.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         4168 a         3129 c         2664 g         5232 t
ORIGIN      
        1 tattgacaaa aagtgactca aaataaaaaa aaccttacat tatactggaa tgaactgtat
       61 tgatagtgta cctaaaagct ctactgacat aagatcgtgt aatcggtaaa gtaattttat
      121 taattatacg ggatgtaatc aattagagaa taaactaatc ataaaaggta cttttacatt
      181 cataattgtc gctttgagat tctactttgg ttcactatct gacccaattg cacattttcg
      241 atcattacaa gtattggtgt cgttagaaca actaaataaa aactagcggt agatttttca
      301 gaatctatgc taatttctgt atggatgttc cagtgatggc aaatttctct tttcattgtt
      361 tttcttgtcg catgatatgc ctttttgtgt tattcagtta aactatagaa attctttcct
      421 agacagatct tgatcccaaa ttttacgttt ttgagcatcg atatagttta aaatgacatt
      481 actcatatct aaagagttta gattttttag gactaaaact gtcagttgtt ctttttcttc
      541 tttctgttaa agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa
      601 gttttgtgac acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat
      661 gctatatatt ctttagttta agatacggaa attaatgcca tcgaccacac tagtagaatg
      721 aacgacattt acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag
      781 agtttactta caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt
      841 gcaatggtaa gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt
      901 gtgtaataat tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta
      961 aattctttat agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt
     1021 cataacgaga gacgactagt cctggtcgtc ttttttgaat ttcttttcct acggagggat
     1081 caaaatcaat ccatacaata tcaccttttt taggaatata aattctttct tctgacacta
     1141 taaaatttct ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc
     1201 ctcttcccca ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc
     1261 agaatacaca acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa
     1321 agttaccact acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc
     1381 cttaataaaa gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct
     1441 agaaaattgt tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca
     1501 gttcattttt tctttaacta aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa
     1561 gctacccaaa tactatagct aaccccccgc taccttcaat tttgcagata aaacgctttg
     1621 ggagaaaatt tcaaagacaa caggccatcc tatcatgccc gattataaac aaaaagctgg
     1681 ctattccttt tgctctgaca aatttcaatt gggaaagttc acgaaactag caggtgaaga
     1741 agtttcaact gttcggatca aagaatgccc gcttcaaata gaaacattgg ttcaacgaat
     1801 ttcaactaga caagactttg ctattgtaga acgtgagatc gtagctattt ttgtagaaga
     1861 agggatttta catgatccaa ctcatatcaa tgtggataaa tggcaacctc ttatctataa
     1921 attcagagaa tatacaactg ccaaccagtc gttaactttg aattttagat tccaagaatt
     1981 caaagagtca taatgataaa catcgttagg tataaataaa aaagactcgc agcacgagta
     2041 aaaaacaaat agaagctata cattagaaag gtcgactgtg accctataga tgcagtatat
     2101 gcagcttatg agcatttctt ctgttctctt tgtttttggg atctgtgctg aagtcttttt
     2161 cgttttttgc cgctctttct ttgaaaaatc gattatgtta taccttctcc attactaatt
     2221 caggcatctg ctgagtaatg atttttcgcg caaaagaaat atctgttacc caaggttcga
     2281 tttgttcttc agtcaagaca agcggcattc ggtcatggat tggtgcgact gtgcggttag
     2341 gttcagtagt cattatgatt gattctgcca ttttttcatc ctgatggcta cgataaaaac
     2401 cgccaatata cactattttt tccttatttg aaaacataaa tttgtctttt tcttcattcc
     2461 actcattggg aaaacacaac gattttgcaa aaatggttga tgaaaggtct ttttttcttc
     2521 tactgtctct gcacgggcat taatcatcaa ttgtcctttt ttaaatccgg taaatcccca
     2581 cttcatgatt tccggagtga ggatgttttc ttcctctttt cttaacgtca caacaagatt
     2641 tgacggaaaa acttctccag ctgctaattc tgctgcctgc ttcggttgtt tcgtctgggc
     2701 ttctcgataa taattctgaa ggagctctga ctctagatca aaaaaataac gaccacacat
     2761 cctaatccct cccaatcttt ttttctatca tacactgcaa caagaagttc gcaccaacaa
     2821 aacgctttca atttttgtag aactaaaaaa gttgtgacaa gtgacaaact ctccagtgaa
     2881 tggtattctc ctgccaactc ctcggtcaca agtcacaata ttcaacaaac atgagaagct
     2941 gctttttgaa attgttcctt gtgactcgga gtgaaacggc aggcttacga cctctgggta
     3001 aacggtgttc aaaagccagt ttctcggtat taagccaaat ttatgcaaaa atgtagaaag
     3061 ctattttcac aaaatttttc ttaatactcg aaactaagcg actttttcac aacctcttcc
     3121 ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga
     3181 gcagctattt ttatttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
     3241 tccactaaac ggtgttcaat cagctaacct tcggtattag ctcaaaaaac ggcaaaatat
     3301 gaggaactat tttgccgttt gtttctctaa tactcaggtc aaagcgctga tttcacaacc
     3361 tctaatacac ggtgttccag aagtagcttc ttcgaaaaat aagccgaaat ttcacaaaaa
     3421 tttgagaagc aattttcgta aattccttct tatttcttga agctgaccac ttctgtcaca
     3481 acctctaatt attaaagaac cttttgcgaa gttaacaatc tttctttgat caattgaaaa
     3541 ttctgcctaa gtagtgatag atcctgtgtg actttcaaca ataagatact tccctggatt
     3601 tcagcaatca acgctttggc ttgacggtct gcttcttcat cggacagttt ttcttcagaa
     3661 agtgccagga tattttgttt cgtatacttg acccattgat tgactaattc tagtagcaac
     3721 agacggtatt cttcatccac tgtactcaac tcaataatca aattacctac aggacagcca
     3781 tgataagtga tctgtgtctc atgatcagcg aaaatccagt ccaacatttc ttctaatgct
     3841 tcttctggct gttttccagc atttaagatg tcttcgaaca attctgtctg ccatacgtcc
     3901 atatgcgcat ggatcaccgc tagacaaact tctttttttg aagaaaagta ataataaaat
     3961 tgaccttttc ctgtatcaga agctgctaga atatctcgga ttgacgtttc atgatagcct
     4021 tttttataaa taagatcttt ggtcgcttcc aagatctttt cctttgtttt caatgatatt
     4081 ctcctttttc atttctcata gtcctatatt atacagtaaa ttcatcattt tttcttctta
     4141 atcgtttaaa aaagactgtg ccaaattatc tgacacagcc ctcactataa aactgttctc
     4201 atatagctag atgttcattg attcaagaac tgcgaggaca aaagcaattc ctatcttatg
     4261 atagttgctc taatacttcc tctgttgtca tcacttgatc tgcaataaag ccaaagttcg
     4321 tcaacgctgc atccattgct tcttggccag gagcaccaat tgcatctgtc gctaccacaa
     4381 cattgaatcc actctctacc aattcacgca tatgggaatc gctacacaag tttccgttca
     4441 ttccaccaag aattactgtg tcgattccat tttttctcaa ttggagcgcc aaatcattgc
     4501 tttctggtcc aaagatttta tgaggagagc tgatgatcgt attttcatcc aaataaggtt
     4561 tcaattcttc gataaaatcg gctcctgaac cttcttccac tgattcatat tgactttttc
     4621 tagcaaacat ctgctgctca agcatcatat gttctcctgc accgccaaat tgccatttat
     4681 ggtcatgtgg gtaaaaataa tgaggagaaa taaagagttt gtatcctttt tcttttgctt
     4741 gttttaccat ttcaatcata ttttcgatcg tattgtattt ttctaagata tcttttgtca
     4801 aaccaaagcc accgcctgct ggtttcaaga actcgacttg cgggtcagtg agaactactg
     4861 ctgtattttt attattgaac atggtggatt ctccattcgt tatttatttt aatacatcat
     4921 ttagagcttc actcattgtc ggatgagaat agatttgatc tctcaataac gtataaggaa
     4981 gttttccatt catagctagc gaaatcaagt tgatgacttc atgagaatct tccgcataga
     5041 tacttgcccc tagaatcaag tcagtttcag ggtcgactaa aactttgaat acacctttag
     5101 gatcttctaa tacttgtgct ttagggacac cgcttgtcat atacttgaat aatttgtaat
     5161 tgacgccttg tgctttggct tgtttttctg ttaaacctac attggataaa gtcggagtga
     5221 taaatacact gtaaggcaca gctttccggt tattcgttgt tcgtttattc tcgcccttca
     5281 actgatccat aatgattcga taatcatcta gagagatata agtgaactgc aatccgcctt
     5341 tgacgtctcc aatcgcccaa atgttgtctg catctgtacg aaggtattca tccacagcga
     5401 ttgctccgcg atctgttagt ttaacatctg tattttctaa tccaagtgat gctgtacttg
     5461 gttttcttcc agttgcagcc aaaacttttg acgcttggat tgttacttct tggccatctt
     5521 ctgtaaaggt gacggcagct gttgattctt ggtctgctac ttgatctaca gatacaccta
     5581 gatggaattc gattcccgca tttgtcatgt cttctaaaat catttgcgcg atatcttcat
     5641 cttcacgtgg aagaaattca gaatgggcat caagaacgac aactttagat ccgtattcat
     5701 tgaacattga tgcaaattcc aagccaatat atccagcccc gatgatcact aatttttccg
     5761 gtaattgttc ctgatccatc gcttgcgtag aatcaatcaa gtagcgactt gtattcaatc
     5821 ctttgattgg taaaatgatt ggttcagaac cagtattgat gaaaatccgt tcgccttcaa
     5881 caatcacttt ttcaccatta ttcgtcactt cgatttgatg gttagaaaga aaacgtgctg
     5941 taccgtccat cactgtccca gttgcctcat cgctgatcat atgataattt ttggcgcgaa
     6001 gcatgcccgt caatttttct ttccgagcaa cagcctctgt aaagtcgatt cctctttctc
     6061 cattgaaaat caatgattta gaaggaatac agccgatgtt gatacatgtt ccgccataca
     6121 tacgtgttga cttttcaacg actaaaaccg attcaccttt tgaagctaac gccttcgcta
     6181 aagtcttacc gccctttcca aaaccgatca caatattttg atatttttcc atcatttttc
     6241 cctcgcttct tttttaccta ccgattggta caaaaatatg ataaccgata attgtctatt
     6301 ctccaaatca tctgctttat ttgtcaaaaa aaaccagaca aaaagcggtc ctttcacgtt
     6361 tttagtctgg ttcgatttcc tttattcttc taaacaatcg ttacttctac atcgatattt
     6421 cctctagttg ctttggagta agggcagaat tcatgcgcat cttctgcaat tttttgggct
     6481 tcttcttcgc tgatgccatc gatatgcact tctaatacta caccgatctg atagccgcca
     6541 tcatctaaat tataaagaga gacacgtgct tttactgtgg actctgctgt cattcctgct
     6601 tctttgatca tatgttgtac cgccccattg aaacaagaag cataacctgc tgcaaataat
     6661 tgttctggat ttgttccttc tgcatggatt cctggaggag tgattttcat atgcatcgag
     6721 ccatttggtg cctcgacttc tccattgcgc ccgccatggt tgatcattgc tgtttcgtat
     6781 gcttttttca ttgtactgct cctttcgatt gaccatttgc tacttggcta taattatagt
     6841 gtatgacaag taaggcgctt tctacaaaaa ttctgcttat tcgaatacca gaatgccgtc
     6901 ttctactatt tttccaaaaa acaaaaaaat actactcgtg aacaacagcg tcatatttgt
     6961 tccaaaataa atagcaatct tttctacata atcttttata tgattgattt taagatacat
     7021 atataccaga aagttgaccc cataaaccaa tactgttaaa aaaataacca tattcgttac
     7081 cattttttcc tccttttgct ggtctcccta ccagcactcg atttaaccat accacttttt
     7141 ttgccgtcca agcaactagc ctttcaaaaa gactggttta ttctgctgtt aatgattcaa
     7201 gatcagaaaa atgtccgaat aattttgcta attttactaa cgccaacttg ttctttccga
     7261 attcatcatt ttctatctgt aatactagta acggctcatg taagcttaaa cggatcaaaa
     7321 accagccgtt tccgtatggc tcttctagat catatcgaat accttcttca ttttccgggt
     7381 cgaagttcat ccctttttct tcttccaaca gtcgcttcat ttcttctaat atcttgtttc
     7441 cttgttcgcg tggttcatcg ctgaacaatt ttaatcggat ttcttgtact tctacgggct
     7501 gtttcaactc tttgatttgt tcatctaatg tgataccttt tctttttaat tctggcaaaa
     7561 gcatcaggat ctttgcgatg acatatgcac catcatccag aaaatagttt tccttgaatg
     7621 cagcgtgtcc gcttgtttcg atggctagct gtgtatcttt cccaagacgg ttaagttcta
     7681 atgctttatt gattacattt cgatagccgg aaatataacg aacttggatg cctccttttt
     7741 cttcaatgaa tctttgtaga tgagaagaag taggggaatt cgtcacgatt cttgttcctg
     7801 gatgctcttt taatacgatt gtacttaata ctgcgatcaa attatttcga ttgatcactg
     7861 ttccagaagc actgacaact gcagaacgat ccacatctgt atcgaaaatg atcccaagat
     7921 ctgcttcatt tgctaaaaca gcctgcttga tactttccat cgcttcttta ttatcaggat
     7981 ttgggatatg attaggaaat cggccatctg gttccaaaaa ttgggaacct gttgaatccg
     8041 cacctaagct attcaatact ttttcagcaa agaatccacc agcaccattt ccggcatcaa
     8101 caatgatttt ccaaccattt agtggtttgc tttctagtgt tccaatcccc tttttaattt
     8161 ttgtgactaa atcttgcgca taaggtgtca aaaggtctgc tttttctacg cttccagttt
     8221 gttcgctttt tattttttgc tgctgtgata ggataaaagc aatatcttct ttttctgctc
     8281 ctccttctga ggtaaagaat tttattccat tataataata gggaagatgg ctagcagtca
     8341 gcataaccgc agcatcgcac gagaactgtt caaattgagt ggacataaac atagcaggcg
     8401 tagtagctaa ttcgaaatcg atgacatgta tcccttgttc tttcagactt tggatcaacg
     8461 cctctttcag tgctggtccg cttatcctac tgtcatgacc aatcccaatc gtccattttt
     8521 tatttggatc ggttgatttc ttctttttct ttatccagtt tgctagtccc cagccgatct
     8581 tttttaccat gtctgtcgtc aagtttactt catatccttc aactggtaat gcgattcctc
     8641 gaatatccga tccattttgc agcgctttca tatctttcat ataaaagtcc tcctcattta
     8701 ttccctcatt ttttccagct tttctgcaaa tcgctgtgct tcttcttctg agcggcaaat
     8761 aataatgaat gtatctacac cggccatcgt tccgacaact tcagggtaag ccacttcatc
     8821 tagccaattc gttaccacat cggcaccatt tcgttcagtc aatacgataa ccatgaactg
     8881 aacagactgg atacgcaaaa cctcgcgtct aattgctgta cgcaaacgtt cttcatttaa
     8941 agaaacagat ggctggttaa ataatgtata gcgtactatt ttgttttcat tttgactttt
     9001 tactaacttc atttctcgaa tgtctcgaga aatcgttgct tgagtcacat cggcgcctgc
     9061 ttcatgcagc cgcgcaagca gctcttcctg tgtcccaata ggttgttctg taatgatctg
     9121 gcggatcagt gcttgtcgct gtttcttttt catattagac acctctcaat gttgattata
     9181 gcaaaagata agtaatattt cttcatattt tggtattttt tacttttatt ttttgttttc
     9241 attcaggttg ctaacctttt tctattttaa cacgcaaaat cgtcttcatt ttttcaggtg
     9301 ctgattttct tggatcgctg atgtaaatct ctttgtgttc tttagaagct ctttcatagc
     9361 cttcttttgc gatgaatgct tctaatttct caaacgttgc tggttcttcg gcatagggcc
     9421 cgacgtgtaa gatttgggca caaagacctt cttccatctt tttgaatact acttgttctt
     9481 tcaagtcttc cggaagtttg ctagaacgct gaatggcttc ttgtgctatc gcttctgtaa
     9541 caaagtcagg ctgtcggatc atcaattgat aagaaaaatg ttcttttttc atcactggtt
     9601 catgcaaata cttttcttgc agtccccatt gtccttccag tggatagaca gtatacatct
     9661 gataatcagg aatcagccaa ttttttttag gcgacatgcg tattgcatag ctgactgcat
     9721 atagacaggc tactcttcgt ttaaagtctt cctgattcgg gtcgccgatc cctctgatgc
     9781 taaagaatga ttttttagga acctctagta tttgcgggct ttttttcata ctatagctct
     9841 tgtctttacg ccattcaatt ttttccattt ttcttcctcc gcgaaattcc atttagttat
     9901 ttattatcat acctcttttt gagtgacttg gctaatcgtg ttgacactat ttttcagttt
     9961 gtgctagaat aagtgaagta aataaatcgt acagataaca cgtttcggcg tgtcgagaga
    10021 gaggcggttt ctatttttat aatagaaatc actctctttt tttacgaaat tttttagagg
    10081 tgatgtaaat gacaaaacaa aaacagctgc ttttagtacc tgcagtaatt gcaacaggga
    10141 tgatgtcttt tgcgggcgta ttgatcgaga cggccatgaa tgtaactttc ccaactctta
    10201 tcagacagtt tgatttaacg actgcacaag tccaatgggt aacaacgatt tatcttttga
    10261 tgatttcgat cattgttccg ctgtctactt atttgaatcg caattttagt ctcaaaaaac
    10321 tctttttagc ttcaaatctg cttttcttgg caggtataat gatcgatttc ttctctccta
    10381 ccttcatggt cctattgttt ggtcgattgc tccaaggtgc agcgacaggt atcgctcttc
    10441 cgttgatgtt ccatattatc ttgacatttg cccccctcaa tcgacgaggc gcgatgatgg
    10501 gtgtcggtac tttgacaacg gccattgctc cagcaattgg ccccacttat ggaggcatta
    10561 tgacttcaca ttttacatgg aatcatatct tcctgtttct tgtgcccgtt ttgtttcttt
    10621 ctttgattat cggctggttt gctattcccg agatggcagt acaaaaaagt ggttatttgg
    10681 attggataag cgttttagga atttgtcttt tgtttagtgg aagtctaaca tttttgagta
    10741 cgttgggaac agtttccagc tggattgctt taatcatcgg cggtattggc tggttccttt
    10801 tttactatcg aagtaaaaaa gtggagcatc cactgatccg actgtctatt ctttcaaata
    10861 aaacattccg cttgtttttg attggcttct tagtttatca gtttttatta cttggtgtat
    10921 cttttgtctt gccgaatttc cttcagatcg ttcaaggaag tagtcctttt gtcgctggat
    10981 tagcgatgct tcccggcgca gcggttggtg ctttgctttc tcctttttcc gggaaaatgc
    11041 tggatcaata tggtccgaag aagccaattt ttgttgggct gattctttct ttgattggtt
    11101 ggctagcatt attcctactc ataggacacg cttcagtggg tgtattgatt gcttgtcatg
    11161 tgttttatat gatcggtatc ggattatctt acagcaatat gatgaccacc ggaatgaatg
    11221 cactgaatga agaactacaa ggagacggga acgcaatgtt caataccttg cagcagtttt
    11281 ctggcgctgt ggctacttca ttagtagcgg tcattatcaa ttacgtccag catcatactt
    11341 cccataacta tgaagtgtct actacattag gatcaaaagc agcattaggc gtcttgttgc
    11401 tgttgcttct cgtaagcttt gctcgattcg cctattatct gttctttgct aaaaaagcgt
    11461 agattccata tacggcaggt gttgcatctg ccgttttttt gtgtgaaaat ggttgtttgt
    11521 aaaaggaggc ttttttatgg aaaaaattgc cattatcggt ggcgggatca ttggtatgac
    11581 cctagccagt tacttagata catcaaaatt caatgttgct ttatttgatg aagggacagg
    11641 acaggcaact aaagctagcg ctgggattat ctccccttgg ttgtcgaaac gcagaaacaa
    11701 acaatggtat cgtctggcta aagacggcgc tgcttttttc cctaaactta taaaagattt
    11761 ccaacttgat caaacgattt acgcacaatc agggacactt ttgcttcgac ctgaaaaaga
    11821 tttagctgaa ttggctgttc ttgccgagaa acgaaaagaa gaagcgccag aaattggaaa
    11881 catcgaatgg ctttcacctg aacagacatc tcaagcactt ccgttattga aaccagcagt
    11941 ttcactgcgt atcagtggtg gtggtcgtct ggatggaaaa gcatatttag aacatcttgg
    12001 tcagcgttta gcacaaaaac aaatggagca gatccaggca aaagtcactt tgcataagaa
    12061 gagcgattct tggctcatca agggaccgtt tggagaatac acagctgatc gtgtaatttt
    12121 gacacctggc ccggcactta agcctttatt acaagaatta ggctatgctg cagatatacg
    12181 tccgcaaaaa gggcagctct tagcatttca gacatcttat aagatgagtc aagactggcc
    12241 tgttgctatg cttgacggag aagctgattt cattcctttc atggatggaa agatcctttt
    12301 aggtgctacc catgaaaacg atcaaggctg ggatttggct cctactagcg aagcttataa
    12361 gggattgact aagagtacag aacagttctt gactgatcca gatcagataa aaaactggcc
    12421 atacgagttc cgtgtaggta cccgtgctta tacgtcagat ttttccccat ttttcggcgt
    12481 actgccagat gatccaagct tactggctgc tagcggtcta ggctcttctg gcttgaccac
    12541 aggtccttat atcggctatc tattagccaa cttcttaaat actggtcatt ggcctacgga
    12601 agattatcaa aaggacatct ccacctatat tacgaaaaat ccatcataga aaaacagctt
    12661 tttcaagtaa ggatcccgag cgatattgcg catggattac ttcttgaaaa agctgttatt
    12721 ttagttcaat ttctgaatca aattctccaa actttctttt gcttcatctg gcaagagatc
    12781 ttttcctatc tgagcttcaa tgaatcgtaa acgaatatca agtcgttgtt tcaccagatt
    12841 tttataggac gtatcctcaa aagaaacagg aaaatctggt ataggtaaat agtggatgtc
    12901 ttcaaatgga ccaaacgact tgaattctgc cgtttgttgc acgattcttt caacgattga
    12961 caatgtcgtt tcaggtttga tttttttatc atcgaaatat ccagtattca ggacatagca
    13021 ggctgtttgc tgtttcaaaa acaactctcg aaaagcttga tagtcttccc taagaggata
    13081 gacacggaaa ggattagcaa atggttcaat gactagctca tctagctgtc tttttgtagt
    13141 gatattttcc gcgtctgatc gttttgttgc taatgttgca ccaaaagacg ctgctaaaac
    13201 tgggtcattg atcttgataa ttggcggaag cgaatcatct ttcatgatcc aaaaaacagc
    13261 atcgatcttt tcgctaagat gatcgactcg gtcgggtgtc gcataacgtg atttgactgt
    13321 ccgcccattt ccgtttcgta tatctcctgt tactaggact ttttctcctt tacttgtaca
    13381 tgtcacgccc acattctgac aagtaaggaa agaagaaatg gccggatcat cagacggata
    13441 gtcttgtgtt ttatcaaagt aagaaggttc caaggcagta gcaaaaccat tttttcgaga
    13501 aataacgaaa gcatcgtcat gcaagatcga aacagagtga ccttccgtat gttttgctaa
    13561 ggtaatcgtt gattttccag aaccggacaa cccaaataca gccatcgtat aggtctggtc
    13621 attactagca tattgtttca tcccaccgtg gcaggcaata aagccattgc gatttcccaa
    13681 tgcccaagca agcgtcaaag tcgctttttt taattctcca aagtaacgta atcctagcac
    13741 agccgctgta ttatggagag catcaaacaa aatgagtcca tttggaaatg tttcatgtgt
    13801 ccattcggga tcacaaaaga tataaagatc tccctcatca aaggaaacag acttttgata
    13861 agtctctaag atcttcgaat tcgctggctg aaaattcagc aaataagaat acaaattgtt
    13921 ctcaaatcct tctggaatca gcaaatgact ttgcacagaa aattcttcag ataggccaac
    13981 gattactttt gtatggtaaa actggcgctt gcgactttga tacacagctt ctcttaaaat
    14041 tttctcgtat ttgctttgtt ccttgtctaa gtcctcaaag atccgccgag cacttgctgt
    14101 tcttcccaca atgcttccat cattgaatac tagtgtccta acatcagctg gtaaatctag
    14161 ttcttcagca tgtgagattg ttaaatctgt gatgatcgtt cctggactcc cttttgctag
    14221 ttgataagct gtcttcctat caaaaacttc atgaacatta ttaccgtaaa atgtcgtttc
    14281 tacaatcgat cgaatactgg ataacagtgg atttccactt gtgatttcgt ttaattcgag
    14341 actctctttt gtactcatgg ctcctcctca ttccctaaac aaaaaaacgt tttctttatt
    14401 atacattatt cgagttttta tttgtactgc tgcgctgtgg gaagcaaacg agttattttt
    14461 cacacaaaaa aaccgagaac ttgaataaac aagtttctcg gtttcatcat tttcctttta
    14521 tcggcttagt accagccgtt tgctaaccag aatgttttag cagcatccca tgaaccataa
    14581 cgagatgtta catattgttc tgctacacgt tcttgattgg cagctgaata gtcgccgttt
    14641 aagtatgaag catctaattg ataacggccg atgtaacgtc cgttagtagc tgtgtatgaa
    14701 ccgcctgatt ctttttgtgc gatccattct tttgcagagc ttgaagttgg cgctgttgca
    14761 gcagctgggg cagcaggagc tacttcaact gtttcaacag gtgcaacgta tgtatgttct
    14821 tgcgttgctg tttcagttgt agatgctgta ttttctgttg ttttgttttc tgttgttgct
    14881 gaagaatcat ttgaagttgg gattgttaat tgttcaccaa cataaatgcg gttgatgttt
    14941 gcgatcgaat ttttttcagc aattgcatcg atcattgagt tgtctcctgc aaatttttgt
    15001 gagatcttag ataatgaatc acctgatttt actgtataaa cttcatcagc gtgagcattt
    15061 gtagttccta caaacattgc agtagcacca gcagcaaaag ttgtacctaa aacaattttc
    15121 ttaaatgaat tcatattaaa ctcctttttt tctccgtttt ttattctttc gacgctatta
    15181 actttatcat tta
//
LOCUS       DAZKPE010000067        15130 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000067 DAZKPE010000000
VERSION     DAZKPE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.067"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(523..1089)
                     /locus_tag="ACG930_002258"
     CDS             complement(523..1089)
                     /locus_tag="ACG930_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0519410.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1089..2045)
                     /locus_tag="ACG930_002259"
     CDS             complement(1089..2045)
                     /locus_tag="ACG930_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFQ0519411.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2045..2701)
                     /locus_tag="ACG930_002260"
     CDS             complement(2045..2701)
                     /locus_tag="ACG930_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFQ0519412.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3071..5089
                     /locus_tag="ACG930_002261"
     CDS             3071..5089
                     /locus_tag="ACG930_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0519413.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5159..5365
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5516..7930
                     /gene="leuS"
                     /locus_tag="ACG930_002262"
     CDS             5516..7930
                     /gene="leuS"
                     /locus_tag="ACG930_002262"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFQ0519414.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8278..9831
                     /locus_tag="ACG930_002263"
     CDS             8278..9831
                     /locus_tag="ACG930_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFQ0519415.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10212..11996)
                     /locus_tag="ACG930_002264"
     CDS             complement(10212..11996)
                     /locus_tag="ACG930_002264"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519416.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12011..13732)
                     /locus_tag="ACG930_002265"
     CDS             complement(12011..13732)
                     /locus_tag="ACG930_002265"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519417.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13832..14593
                     /locus_tag="ACG930_002266"
     CDS             13832..14593
                     /locus_tag="ACG930_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFQ0519418.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4925 a         2772 c         2980 g         4453 t
ORIGIN      
        1 catctggaat ttatcttttt tactgctttg atcataaaag tctgcatatt catcactgat
       61 attttttcta ataaattctt ccatcataaa aatcacctca aaacgattat acgaacttac
      121 gttcttgttg taaagcgata tttgaggggc aaaaaagggg cataatttga ctgatattaa
      181 gttagctatt gatatatgaa tgacatacaa aaatataaaa tcttttaaaa atgcttatat
      241 atcaatgttt ttgccattct tttatatatc tgttatatgt caaaaaaatg tgttcaattt
      301 caatttgtat ttgaataaag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca
      361 gccaatcaaa aacagcttct catgtttttg atttggttgg acttattacc gcagatataa
      421 gcttttgagc accgtgaata aagaggttat gaaatcaacg ctctaacctg agtattagag
      481 aaaaaaacgc aaaacatatc atttatgttt tgcgtttttt atttatcttt ttttctcaat
      541 acaatataaa ataggcggct ggttcttttg gttgataaac cgataattca gcacattata
      601 tgtttcctgt ggcagtttgg aacaaaaaga atcaaccata tccagttctt tttctccacc
      661 ttcatgacca tagtagacga caaggatcaa tcgtccgcga ggcacaagtc gtttcaatat
      721 ttcttccata gctgtgcgtg tagtctctgg catagtgatg attgctttat cactttttgg
      781 gagataccct agattgaaaa tccctgcttt gagattttgt tgttcagcta tcacttctcc
      841 taacgtttcg tggccttgta gaaacaatga gacacgttct tctaactgac gctgttctag
      901 cctttcacga gtagcatcga ttgcttgttg ctggatatca aaactataga catgaccagt
      961 ttttccgatg tgttctgcta ggaaaaccgt atcgtggcca ttgcccatcg ttgcatctac
     1021 gacgtgatcc cctggttgca agatttcttg cagtaatgta tggctgaaat gcaaagcagt
     1081 ttgcaacatc agacgctcac ctttttccgt acatcatatt ttccttggaa gctatctctg
     1141 cgaagaagtt cttcatcaat tgcattcaag acttcccatt ttttcaagct ccacattggt
     1201 ccaatcaagg aatcccacgg cgcatcccct gtcaaacgat ggatgatgat ctcttttggt
     1261 atcatttcca gctggtcgca aatgacattg acatagtcag gacggctcat taattgaagg
     1321 cgaccttcat gatagtcccg caacattctc gttttgcgca tcagatgcat caaatggagc
     1381 ttgattcctt ggatatctga atctaaaatg gtgcgtctga cattttcttt catcatttct
     1441 aaactttcgc ctggtaatcc gttgatcaaa tgcgtacaaa cacggatatt atgtttgcgt
     1501 aatttagcca cgccatctaa ataagtttga taatcatgtg ctcggttgat cagttttgaa
     1561 gtttcttcaa aagttgtttg caatccaagt tctacccata aatacatccg ctcgttcagt
     1621 tcagcaaggt aatcaactac ttcatctggc agacaatccg gtcgtgtacc gactgataat
     1681 cctacgacac ctggtaaatt gactacttgc tcaaatcgtt ctttgattat ttcaactggc
     1741 gcatgggtgt ttgtaaaatt ttggaaataa acgatgtatt gttggacatg aggccatttt
     1801 tgatgcatca tgtcgatttc tttctggaat tggattggaa gagggtcttc aggtgcaacg
     1861 atcatgtctc ccgaaccaga tacactgcaa aaagtacaac cgccatgggc aacagtccca
     1921 tctcgattcg gacagtcaaa tcctccatcg atcggcacct tgaaaatttt cccgccaaac
     1981 tcatttcgta aagcgtaatt ccaagaatga tatcttttat ttccttctga ataaggaaaa
     2041 gtcattaaaa gtccttcttt ctgtaagagt tatctatttg ttttcttttt tctctataca
     2101 ctggataagt caggcacagc caagaaagac tgagtaagta gccgccgatg atatcagtag
     2161 gaaaatgaac gcccagataa atgcggctta tcccgacact tactataata aacatcatca
     2221 gcaattgaag caatgtgcgt aaggttcttt tttgaacaaa agctggaagc agaaatagta
     2281 aagaaccgta aagaatcata ctgcctgctg catgtccact agggaaactg taacttgttt
     2341 caactactaa gtgcgccaat gaaggacgct ctcgcatgaa aaatagtttg atcaccgggt
     2401 tgatgattcc agcaattaca ataaatccag aaacgaacca aaatgtttct gccctttttt
     2461 tcttatacca catccataaa gccgcacaag caaataaaat gatgacggta agaggattac
     2521 cgaatttagt cataaagagt tggtagctgt tcagatcagg ataagaagct ctgacaatgc
     2581 ctgtaaacca ctgatcgaaa ccagaaagcc acgacagatg gaactttacg atccagccca
     2641 aaatgaaaaa caggacaaga aagaagctac cagccacctg aaatgatgtt ttatatttca
     2701 tacaattcct cctttgaagc aatgacttat tatagcattt ttggtccagc gaaaaaaacg
     2761 gtaaagagat aaaaccaatg tatgattcct ctttgaataa ccaatattct tataaaaaaa
     2821 ataactgtaa tcggaaagac attttttggt aatgcaaatg aaatgttagg gaaataaaat
     2881 cagtgttttt cgaaatcctt ttaaacaaga acgtagacgt aggaagaact tgaaaatgaa
     2941 cagaagttgt tcattacggt aaattacaat atgattacaa aaaacaacaa agctcttaaa
     3001 taacttttaa taaatattaa gagaagttat aattattaat aatagataaa ttgaagttgg
     3061 aggatagaag atggaaaaca ttgcaagaaa agaacggaga cgtttagaac agaccaaacg
     3121 ttttcgaaaa gcaaaacgag gggcagcaat cgtgggaact gcgatggtag gctgttctgt
     3181 cgctgcccca ttagtacagc cggttcctgt tcaagcggat gaaacacctg ttcagttcgg
     3241 cgcaagaatc aatacagcgg catttatcac agaaattgct acttatgctc aaccaatcgc
     3301 tcaagccaac gatctatatg catcagtgat gatcgcacaa gcagttgtag aaagcggttg
     3361 gggcagtagt gcgttatctc aagcacctta ttataatctt tttgggataa aaggcagcta
     3421 tcaaggacaa accgtctaca tggatacgct tgaattttta aataatcaat gggtaaataa
     3481 aaaggagcct ttccgacaat atccttcttt tgctgaatct ttcaatgaca atgcctatgt
     3541 acttagaaat acttcatttg gcaacggtta ttactatgcc ggtacttgga agagcaacac
     3601 gaaatcctat acagatgcga cagcttgttt gacagggcgt tatgcgactg atcctggtta
     3661 cgcaggcaaa ttaaataata tcatcgcaac ttacggattg acccaatatg atacaccagc
     3721 tagcggaaac gcaggcggtg gagcgactac aggtggcaat aatactggaa gtgcaggtag
     3781 tactggcggt tcaagcaatt ctggtaatac aaactcaggt tcagcaactt cgaccactta
     3841 tactgtccaa tctggtgatt ctgtttgggg aatctcaaat aaattcggta tcacaatgga
     3901 tcaattgatc caatggaaca acatccaaaa caatttcatt tatccaggac aaaaactgac
     3961 aatcaaaggt agccaggaaa atggctcttc gacgaataat tccggtaaca ataccaactc
     4021 ttcaggaaat gctggtacat caaacggagg acaaacaact ggtgcgaaat acactgttca
     4081 atctggtgat tctgtttgga agatctcaaa tgatcacgga attacgatgg ctcaattgat
     4141 tgaatggaac aatatcaaga acaatttcgt ttatccagga caacagctaa tcgtatcaaa
     4201 tggcggttct tctaatgctg gagcaaatac tggctcaaat actgggaata caagtggctc
     4261 tagttcgtcc agctcaagtt cttctaatac agcttcagga acgaaatata cagttaaagc
     4321 cggagactct gtttggagcg tctcaaataa atacggaatt acgatggctc agctaatcca
     4381 atggaacaat atccaaaata actttatcta cccaggacaa caactgactg tttcaaacag
     4441 tggatcaaca aacagcacgt caggtaatac aggttcgtca accaatacaa ataacagcag
     4501 ttcagttaat actggcagca gttcgtctca aggcacttat accgtgaaag caggtgaatc
     4561 tgtttggagc gtggcaaata aaaacggcat cacgatggat cagttaatcg aatggaataa
     4621 tatcaaaaac aacttcattt atccaggaca gcaattgatc gttaaaggtg gaacttcggc
     4681 aaatacaaat acaggttcaa ctacttctgc agcgaaacca aatacaccga atacgtctgc
     4741 tacgacaagt acatcatcca ctggtaatac gatgtatacc gtgaaagcgg gcgagtcagt
     4801 ttggagcgta gcgaacaaac atcatatcac gatggatcag ttaatcgaat ggaataatat
     4861 caaaaataat ttcatctatc caggacagca agtgattgtg aagaaaggtt catctcaatc
     4921 aacaaaccaa caatcagtta ctggttcgaa aacctatact gtgaaatctg gagaatctgt
     4981 ttggagtgtt gctgacagtc atggaattac aatggctcaa ctaatcgaat ggaacaatat
     5041 taagaacaac tttatttatc caggtcaaac gttgattgta gctaaataaa atagctgttc
     5101 gaagaaataa cgattgaatt ccacaaaaat atttgttact ataaggctac ttaaatatga
     5161 caacacttga aaaggaagta gtaaaaagac tgaagtttca gagagcgcat ggctggtgag
     5221 aatgtgcacg gatgcttttg aactcgcctt tgagttgccc ttgctgaata cccgagtaag
     5281 caagcggcgg tgacggccgt tacaacgttc gaggcctttt cactaaggta aaattaggtg
     5341 gtaccgcgta gattacgtcc tataaaaaga gcaatctttt tataggattt ttttatttct
     5401 tttgtgaagt ttgagaaaac aaagcaaaag gaaataaaaa taaacagatt ctgccggttt
     5461 tttcgttata tttataatag aaacaagtgt tttcaataga acaggaggac agcaaatgag
     5521 ttacaatcat aaagaaattg agaaaaaatg gcaaaaatac tgggcaaaaa cgaatacttt
     5581 caacacccat gatgatcctg aaaagccaaa attttacgca ctggatatgt ttccctatcc
     5641 atccggtcaa gggctacatg tagggcatcc tgaaggttat acggcaacgg atatcctttc
     5701 acgtgtgaaa agaagtcaag gatacaacgt gctgcatcca atggggtggg atgcattcgg
     5761 tctgcctgct gaacaatatg cgctagatac aggaaacgat ccagctgagt ttacccaaaa
     5821 aaatatcgaa acattccgac gccaaatcaa ttctttagga tttagttatg actggaatcg
     5881 cgaagtgaat acaactgatc cggagtatta taaatggaca caatggatct ttacgaagct
     5941 ttatgaaaaa ggtctagctt atgaagcaga agtagcggta aactgggtac ctgaattagg
     6001 aacagttatt tcaaatgaag aagtgatcga tgggaaaagt gaacgtggtg gctatgatgt
     6061 agtcagaaaa ccaatgcgcc aatggatgct gaaaatcact gcttatgctg atcgcttatt
     6121 ggatgatcta gaattagttg attggccaga aagcattaaa gaaatgcaaa gaaattggat
     6181 cggtcgttca gtaggagcaa atattgaatt taaagtggct ggtacggata aatcctatac
     6241 cgtatttacg acacgaccag atactctatt cggtgcaact tactcggttc ttgcacctga
     6301 actagatctt gttagagaaa ttacgacccc tgaacaaaaa gctgctgtag aagcttatat
     6361 cgaagagaca gctaaaaaat cagatctaaa gagaacggat cttgcaaaag aaaaaacagg
     6421 agtatttact ggtgcttatg caatcaatcc agttaatggc aaggaaatcc caatctggat
     6481 cgccgattat gtattatctt catacggcac aggagccatc atggctgttc cagcacatga
     6541 tgaacgtgac tttgaattcg ctcaaacttt cggactagaa attcttccag ttatcgaagg
     6601 tggagatgtt gaaaaagctg cttacacaga agatggtacg cacatcaact ctgaatttct
     6661 agacggcatg aacaaacaag aagcaatcga taaaatgaat gaatggctag aagaaaatgg
     6721 cgtagggaaa aaagaagtca gctatcgctt acgtgactgg ctattctccc gtcaacgtta
     6781 ctggggtgaa ccaatcccaa tcatccattg ggaggacgga acagtcacag ctgtcccaga
     6841 agaagagcta ccattacggt tgcctaagac aaaaaacatc aagccaagcg gtactggaga
     6901 atctccatta gcaaatatcg aggagtgggt caatgtcgtt gatcctgtaa caggtaaaaa
     6961 aggccgtcgc gaaacgaata caatgccaca atgggcagga agctcatggt attacctgcg
     7021 ttatatcgac cctcataaca aaaaagaact agcagattat gaaaagttga agcgttggct
     7081 accagttgac atctacattg gtggagcaga acatgcggta cttcatttac tatatgcacg
     7141 attctggcat aaattcttat acgatatcgg tgttgttcct acaaaagaac cattccaaaa
     7201 actatacaat caaggaatga tcttaggcga aaacaacgaa aaaatgtcaa aatctcgtgg
     7261 taatgtagtc aatcctgatg atgtggtcga aacttacggt gcagatacac tgcgcatgta
     7321 cgaaatgttc atggggccat tagatgcttc gattgcttgg agcgaaaatg gcttagaagg
     7381 aagccgtaaa ttcttggatc gtgtatggcg tttgatcgtt gatgagaaca ataaaatgcg
     7441 tgaccgtatc actacattga atgatggcaa gcttgataaa gtgtatcatc aaacagtgaa
     7501 aaaagtgaca gaagactatg aaaatcttca tttcaataca gcaatctccc aattgatggt
     7561 ctttatcaat gaagcctata aagtggacgc tctgccttat gaatatatcg aaggatttgt
     7621 tcaactactc gcaccgattg ctcctcacat gggtgaagaa ctatgggcaa tccttggaaa
     7681 tgatggtggt atttcttacg caccatggcc aacatacgat gaagcagcac ttgttgaaga
     7741 cgaagtagaa gttgttttcc aagtaaacgg taaagttcgt gcgaaaagca atgttccccg
     7801 agacttagga aaagatgagc tagaaaaagc agcattagcc aatgaaatag tgcaagaata
     7861 tattgaaggc aaaacagtca gaaaagttat tgcggtacca aacaagttag tcaatatcgt
     7921 tgctaattaa ttggctcttt gtcaataagg actgatgagt tgtgcaaaat caaatctggg
     7981 ccagaatgaa cttcattctg tctcagattt tttgttattt caaattgatt aattgattga
     8041 tcaaaaaggt tttgattttc atgttctcaa acacgttcaa tgtctttttc ttctgaatgg
     8101 tcttgtaaga gatctctgta atcatcaaat ttttgtctat taatcttagt attttttgat
     8161 gtataaacta cctgaaattg agagtacata ccaaattcat aaatttttta ttagtgggac
     8221 tagtgattgt atggattttg acgcataatg aatgaagtat gagaaaagga gagacaaatg
     8281 gatcaagaac tatttattat cgaagtatta tcagctaaac aaaaaattat cgagaaagcg
     8341 aaaaaaagag cgaaaagaat aatgttcaag cttttaagct tagtattttt ctctggtttg
     8401 ctttttttcg gagctgtatc gttcctatat cgccatatga gtgcagtagt ccgttcagct
     8461 gaagggatgc aaaaattaaa taatttgtat cacttttcgt ggggagttgg cggaataaca
     8521 attgttgtgc ttattgtttt tcttctactt atttggctcc gttaccatca attgtcgcgt
     8581 catttcgatc aatggcttag tcaaagagca caacagtttt tacataataa accaacttct
     8641 caagatgatg actatcttta ttttgagaag acttcgacga gtcaagcttt tcggatacaa
     8701 aaaagtgatt gccagttatt gctgagatca cttgatgatt tacctatcta cttaggcgaa
     8761 agcaaatcaa aattcggaat gaacacattc catatttttt tactagaaaa cgaacccaga
     8821 tgggaaaaaa gccagtcttc gcctggtgga tacctgacaa ctaagatgag tacattagtc
     8881 actggttttt tcctcattct tttagctgga acaatctatt atgggagata cactcagcca
     8941 aaaatgtctt ctcatataaa tgctgcttct cacatgacaa tgaactcaac taacgatacg
     9001 catatacaaa agacaaatga agggttgtta gctgatccta agcaaaaggt aaatttgaca
     9061 acacaaaaga taaatgatct caaacttgat acagagacgc actctctcta tatgacaaca
     9121 gatagtggtg ctaattgggt atttgtgccg attgattcgc aatggttgcg ttttggcgaa
     9181 tacaccctga caacggggct gattcctgaa ggttattgga tggacaacac atatgatatt
     9241 tccgccgatt tctcatggtt tatctattct tctggggatg atgtacgtct gctgacttca
     9301 agagataatg gtaaaacatg gcaaacgtct attatcaccc aatcagttca gccgatacgt
     9361 tatcgaaaag cggtatttta tggcaacgat ggtctattta tctgtacatc agccagtggg
     9421 atgtctgcag aaactttgta catttacact actatggatg gcggaatcac ttggataaaa
     9481 agtggaagta caatgatcaa tcagccagta caaaatgtca gcttcgttac aacttcttta
     9541 ggttttgttt cgacacgtga aagtttgttt tatacaaaca acggaggacg ctcattcaaa
     9601 gaatcagttc tgtcgattcc ggaaaactat cagacagggg ggatagatct ttttcaatca
     9661 ccaaatgaag ttactcaaat aagcgcgaat acgttagaga caaaatttta tttgttgaaa
     9721 aaaggaccaa tcgatgcagg gaaaatgttt gcctgcctct tccgttcaac tgataacggg
     9781 gaaacatggc aattcgttca gcaactatcg caagtagaac aaggagatta aagaagagag
     9841 attgtgagcc tgacgttcag caccgagtca caagaaacaa attcaaaaaa cagcttctca
     9901 tatttgttga atagtgtaac tcgtgattcg gagttgacaa gagcaacaag aagcgatttt
     9961 gaagtatagc ttctcgtatt ttacaagatc gtgtcttatt gccgataggt tgtctcttga
    10021 acaccgttta ttcgtaaaaa gggattgtga caagtctttt gtcactactt accgaacgaa
    10081 actgaaggag ctatccaaaa agtatcatta gtattattct ttgtgtttct agtggcacca
    10141 ctagtacatt taaaaaagct atcgatcatg gactaatcat acatgatcga tagcttttta
    10201 gataatgttt gttacgctat ctgaaattga ctattataaa gactggcata aagcgttggt
    10261 gattggagta gttcagaatg tgttcctttt tcgacgatat cgccattctt cattacaagg
    10321 atcatgtctg cattttcaat cgttgacaaa cggtgtgcaa tcacaaaact tgtcctatct
    10381 tttgtcacag cttccattgc ttgctgaatc aatgcttctg ttcgtgtatc tacgctagaa
    10441 gttgcttcat ctaaaataac gacaggagga ttcgctagaa tgactcgagc aattgtcaat
    10501 aattgttgct gtccttgaga taacgtgccg ttttcgctag aaatgatcgt atcatatccg
    10561 tctggcagtg ttcgaataaa gtgatcacat tgtgcgattt cagccgcttc gataatttgt
    10621 tctcttgtgg catccatttt cccgtaggcg atattatcag ctaccgttcc ttcaaacagc
    10681 caggtatttt gtaaaaccat cccaaaagaa cgacgtagtt ctccacgtga aagcttggta
    10741 atatcaagac cgtcgaattc gatctttcct ttattcagtt cataaaaacg catcagcaga
    10801 ttgactaaag tcgtttttcc tgcaccagtt ggaccaacga tcgctaccgt ttgttttggc
    10861 tttactgaaa aatcgacttg attcatcaat attttatctg atgtgtaacc aaactgtaca
    10921 tttttgaaag ctatttttcc tttcggttgt tctaaaagtc ttgcatctgg aaggtctgga
    10981 atttcatctg tttcatctaa tatctcaaat atcctatcga ttgctgccat tgcggattgg
    11041 atcgagttga tcacataaga agcggtagaa attggttcag aaatctgatt gatgtactga
    11101 agataagctt gtaagaagcc gatcgtcaca ccacctgata gaacaagcat agcaccgaat
    11161 accgcactta tgatgaaggc gagttgatta atgaaacgaa tggccggata gatagcacag
    11221 ttcataaatt gagcacgttt aaaagcgttg tattgctttt tatttacttc gtgtatagca
    11281 gcttctgcat gagcttgctg attgaatgtt ttgaccacta gattaccagc taagatttct
    11341 tccattcgat tatttaaaac acccagttca tactgattct gttcagaaat ctgtttgttt
    11401 ttgttcgcaa tcttagttgt aacaattgaa ctgccaacga tcagcaataa gacgagcaaa
    11461 gtaagcttgc tttcgatata aaacagcatc agaccagcag cagctattgt tacgacagaa
    11521 gtaaaaaatt gattgatacc tgtcaataac acttgagaaa gttgattgag accggtagtt
    11581 gtccgactaa tgatgtcacc tacttgatga ttgtcaaaaa acgacatcgg taatgttttg
    11641 aatttttttg tgatttcttt tcgcaccctc aatgtgatct tttcgcttaa cgctgccatt
    11701 gtccgttcct gaataaatga agtgatgctg cttaagactg aacagccgat cagcaataag
    11761 acagggaaca acaatgcttg tttgatatca ctgaaagaaa gctgtccaat acctgttttt
    11821 cttatttctg ataagagatc atcgatcccg attcccatga tcaagggcat ggctacgact
    11881 aataggttcc cgaataaact gcatagaaac aatccgtaaa aatatttatg ttcaggtttg
    11941 atcattttcc aaaaacgtat caaagcacgc gtgttcaacg tttttttctt ttccatcgta
    12001 tcccttcttt ctatattcct tgtgattttg caaactcctg ataagtttgg caattagaca
    12061 gtagttcttc atgagtacct tgtccaacga tttttccttc atctaaaaca atgatgttat
    12121 ctgcttgttg gattgtactg aggcgttgag caacaatcac gagagttttc tccgacatgt
    12181 gtttatgaag ggctgctctt aatgctgcat ctgttttata gtctaaagcg gagaaactat
    12241 catcgaatac atagatctct gctggtttga tcaacgctcg agcaatacat atccgctgtt
    12301 tctggccccc tgaataatta gaaccgcctt gagcaacaaa gctgtccaat ccgtcaggaa
    12361 gggtgtccac tagttcttct aattgagcga tcttgatcgc tttagacaac tcttctgttg
    12421 aggcatattc atttcccatc tgcaagttgc ttaaaattgt cccgctgaat aagaaagcct
    12481 tctgagggac ataactgatg tgggagcgga tctgttcttg agtcatttga gtaagaggaa
    12541 taccaccaag ggttactttt cctatcgtag ggtcactaag tctcaagaga agtttcgcca
    12601 aactactttt tccagatccg gtcccgccaa cgatcgctgt tgtttttcct ttaggtattg
    12661 tgaaatcaat atcttctaga actggatcag agatttcagt atatttaaat gtgacatgtt
    12721 caaaagcagc tgcatttgtc tgatcaaagg ttggttcagc tactgttttg atcgtctctt
    12781 cctcaatttc gatctctgct tgcagtattt cttctatccg tcgtaatgag gcaaacgatt
    12841 tagggataat gaccaatacc atagctgcga tcatcaagta agcaagtgtc agcatagagt
    12901 attcgactac agcagtcacg acaccgattt gtaatgctcc ttctgctaca agatttccgc
    12961 caaaccacaa aatagaagca taaacgattc ccatgagcaa aaaagcaatt ggagtgaccc
    13021 aagcaaatat tcggttcact ttgatcattt gattagcata gtcagcaaag ctcttattcg
    13081 ttcgcttttc ttcatatgat tgattatcaa aggcacggat catattaatc ccagtaaaga
    13141 attctctcaa tgtgatggtg atccgatcca tttttggctg gatactcaaa gataaaggtg
    13201 cccctcgttt catcagtcga taaacaatcc atacataaaa aacaacagag atcaatgtaa
    13261 cccatgttag taatagagaa taacgaaaca tcatgagaat ggtgaaaacg caaataaccg
    13321 gtgctggtaa gatcatttgg caaaataaaa caatcatttg ctggacatta tcgacatcat
    13381 tcgtcattct tgtcaaaaga gatccagaac taaaacgact gatatccttc attgacagct
    13441 gttggaattt acggaaatat ttctcccgcg tttggaatcc aaacctagcg gaagccaatg
    13501 ctgaaaagta actagaggca actgcagcga ttgttcctag aaacgctaca agcagcattt
    13561 caactccaat tttttttata actgaggctt cgccacttgc tatacctgtg tcgatcagct
    13621 ttgctactaa ttttggtaca cctaatgtac cggcgatttc taaacagatc atcacaaagg
    13681 taaggagagc gagtcctttg tttttctgta agaatgtttt taagatagac atattattcc
    13741 tccttttttc ctgatacttt tcgattctat accttcaagt aacttgaagg tcaatagaaa
    13801 aaagaataaa ctgaaaaaga ggtgagaaaa aatgaaaaaa atgtatacga ttggccaagt
    13861 atcggaacta tttgatttgc caaaatcaac gatccgctat tgggatgaac aaggattaat
    13921 ccgttcaagt agacaagaag agaatgatta tcgattgttt gatatcgatg atatttttat
    13981 gctttatgat atcgtttttt atagaaaatt agatataccg atcaaacaga tgaagaattt
    14041 atatggaaaa acattgacgg agttatatga gacacttgat gaaacagaaa gaagaatcca
    14101 taaagaactg gtggtgatga aacaaaaaca aaaagagata agggagcaaa aaaaacagtt
    14161 gaaattgatg atcgatacaa acgaggaaga atttcctgta gaagagatcc cttttgactg
    14221 tatgatctca acggagtttg aagatattgt ggaaatcaaa aaatttctac ctaactattc
    14281 aagctttggg atgatgagta tgccagcttc cagttcacag acgatgtatg gattttttat
    14341 cgaccctagt gaagtacatt tatttactca agacgtgatt tgggagaaaa aagatacggc
    14401 tgtttatcgt cgattcttat tgaaatccga gatgaaccat gcggaacgta ataatatttt
    14461 agaaatcaga gaaagaatgt atgaaaaagg atggaaaaca ggagaagtga tcggccagta
    14521 tctattgacg aatacggatg aaaacaatat cagaactgaa tattatcatg catggataga
    14581 aatgaaaaaa taggaaatat gtgtttaaga taactcgaaa atgatggttg ttttagttat
    14641 aaagaaaaat tttctggttc gattacgggt ttaatgtggg ggattattag tcgtggatag
    14701 atagaatttt agttttttag aggaaatatg tctttaaaaa tggaatggtt gcaattctta
    14761 gcgatatata cgatgtaatt gtcctcttaa aaaagtatgg aaaaataatt gtattgggtg
    14821 ttatgtataa ttcatggtga actgagacta atgagaagaa aaattcatat tgttatgagt
    14881 gagattgtat cagatgagaa tgataaatta aataggtgca taaaagcatt acacttaaaa
    14941 tacattgttg cttacattat tacaatatgt taataaggca aaaataaata gatggattga
    15001 ataaacatat tttttaatca aatagtccct actgtgactt tcctcagcta tcggtgatac
    15061 taccgatagc atttttttgc ttataaaata attataagta tttagagatt tttcttctaa
    15121 cattcttcaa
//
LOCUS       DAZKPE010000068        14744 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000068 DAZKPE010000000
VERSION     DAZKPE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.068"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            221..1960
                     /gene="yfcC"
                     /locus_tag="ACG930_002267"
     CDS             221..1960
                     /gene="yfcC"
                     /locus_tag="ACG930_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFQ0519419.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2117..3301
                     /gene="iadA"
                     /locus_tag="ACG930_002268"
     CDS             2117..3301
                     /gene="iadA"
                     /locus_tag="ACG930_002268"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFQ0519420.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3412..3615
                     /locus_tag="ACG930_002269"
     CDS             3412..3615
                     /locus_tag="ACG930_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFQ0519421.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3716..4378)
                     /locus_tag="ACG930_002270"
     CDS             complement(3716..4378)
                     /locus_tag="ACG930_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519422.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4391..5893)
                     /locus_tag="ACG930_002271"
     CDS             complement(4391..5893)
                     /locus_tag="ACG930_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519423.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6441..8120
                     /locus_tag="ACG930_002272"
     CDS             6441..8120
                     /locus_tag="ACG930_002272"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFQ0519424.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8247..8726
                     /locus_tag="ACG930_002273"
     CDS             8247..8726
                     /locus_tag="ACG930_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFQ0519425.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8945..9625
                     /locus_tag="ACG930_002274"
     CDS             8945..9625
                     /locus_tag="ACG930_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFQ0519426.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9633..10964
                     /locus_tag="ACG930_002275"
     CDS             9633..10964
                     /locus_tag="ACG930_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFQ0519427.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10979..11941
                     /locus_tag="ACG930_002276"
     CDS             10979..11941
                     /locus_tag="ACG930_002276"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFQ0519428.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12052..12390
                     /locus_tag="ACG930_002277"
     CDS             12052..12390
                     /locus_tag="ACG930_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFQ0519429.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12469..13176
                     /locus_tag="ACG930_002278"
     CDS             12469..13176
                     /locus_tag="ACG930_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFQ0519430.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13311..14651)
                     /locus_tag="ACG930_002279"
     CDS             complement(13311..14651)
                     /locus_tag="ACG930_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0519431.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT         4648 a         2614 c         3226 g         4256 t
ORIGIN      
        1 aaaataaaaa aagaatttta aggaaaaaca gagaaataaa atacttaata taaatggaaa
       61 gagaaaaaaa taatcataca taggagaaaa aaaacaaaat agaaaaaagt gattttctaa
      121 taaattattc atgtggaaat gtcattttta ctgtataatt catttgatta tccatttttt
      181 attcatcaaa attactgaaa aaagaaagga agaaataaat ttgaagaaaa caaattcttc
      241 aggaaaaccg aaacgcgact tcactaaatt atcgacaccc catacgtatg tcattatttt
      301 tggtgtagtc atctttgcat ggatactgac ttttgtcgtt ccagcaggaa agttcagcac
      361 gcaagatatt gaatacaaag atgcaaatgg cgaaacaagt actcgtactg ttttacgtca
      421 agattccttc cgttatgctt acgagctgga taagtcgtat gtgtttgatc aattagaaga
      481 actgcaagat catccagcag aacgtgaaaa actggatgtt ccggaaaaag gattggaaaa
      541 agtcattgct gacggagaaa aaaatcttac gcaggaaaaa ctagatgaaa tctccttgac
      601 agatgatgtg ctttacgatc agtacggcga aaatatctat gatacttcta aaaaattgca
      661 taaaacagcc aaaatatggg gaacagatga ttttggcggc tttggtttct taaattttgt
      721 ttttgaagga ctagtatctg gagataagta tggatctgct gtagggatcg ctgcattgat
      781 ccttgttgtt ggaggtgctt ttggtattat tatgcgtacc ggagcgatcg acgcaggtat
      841 ctatgcgttt atcagtaaaa ctaagggact ggagcgttta gctttaccgc tattattctt
      901 tgctttttca ttcggtggcg ctacattcgg gatggcagaa gaggtaattc cattctcaat
      961 ggtgatggtt ccatttgtca ttgcgttagg atatgactcg atcgtagcag taaccgtgac
     1021 ttatgtcgca tctcaagtcg gaaatgcgac ctcttggatg agcccgttta gcgtagcggt
     1081 ggctcaaggg attgctggaa tccccgtgtt gtctggtgcg acattccgat tgattatgtg
     1141 ggtagttgtt actgcattag ccgctggtta tatgatgata tatgcagaaa aaatccgtaa
     1201 aaaaccagaa agttcgttga cttacaaatc agatgattat ttccgttctc atatcaaaaa
     1261 gacatctgat gaaaataaaa aattcatgct tgggcataaa ttgatcttat tagagatgtt
     1321 agttgtcctt gtctggatcg tttggggcgt gactcaaaaa ggctattaca ttccagaaat
     1381 cgcttctcaa ttctttgtga tgggattagt tgctggaatc attgctgttc ttttcaaatt
     1441 agatggaatg aaagtcaatg acatcgcttc ttctttccaa tctggtgcag ctgatttagc
     1501 tggtacagca atcgtagtag gtatggccaa agggattctt cttgtcttgg gaggatctga
     1561 tgcatctgtt ccttcagctt tgaatacgat tttgcatggg atcgggacgg cgttgaccgg
     1621 tgttccagct gtcattggtg cttgggcgat gtacatcttc caaagtttgt tcaacttggt
     1681 tgttacatca aattcaggac aagcagcttt gactatgcca atcatggctc cactggcaga
     1741 tttagtaggt gtatccagac aagtagcagt tcttgcttat cagcttggtt caggttttat
     1801 ggacgctttt acacccgtat cagccagctt gattggtgtg ctaggtgttg cacggatcga
     1861 atgggcaaaa tgggcaagat tccaaatcaa gatgcaagga ttcctgtttg ttttaggaac
     1921 tattttcatc atgattgcca ttgcaatagg tctgcagtag tactggagac ctgtaaataa
     1981 aaaagtaatc caaacagtag ataaggactc caagaaccgt cattttacgg taaaatcaaa
     2041 ggagtaaaga tcctatcgtt tggattattt tttaagatcc tatcatcagt tatacttaaa
     2101 gaaagaggaa aaatgtatga aaatcattcg acaaattgaa gtgtttgcac cagattactt
     2161 aggaaaaatg gatgtactga ttgccggtgg gaagattttg gctgtagaag aacagctaga
     2221 aggcggctac gaaggagtgg aagtagaaga actttcaggt gagggaaaag tactaacccc
     2281 gggtttcatt gactgtcatt tccatatttt aggtggagga ggagaaggcg gttatcaaaa
     2341 tcgaacgcca gaagtcacat tgagccaatt gactacagct ggtgtaacga cagttgtcgg
     2401 ttgtttggga acagacggag aaggtagaga tatgactgcg ttgatcagca aagcgaaagg
     2461 tctggaagca gaaggaatct ccacttatgt atacgaaggt tcgtaccgat tgccggtaaa
     2521 aacagtaaca gattctatca tcaaagactt tttgacaatt gataaaatta tcggaatcgg
     2581 agaaatcgca gtatccgatc accgttcttc tcagccaagt tttgaagagt tcgctcgtgc
     2641 agtagcagat gctcgtgtag gaggcatgtt atccggaaaa gctgggatca tcaatgtcca
     2701 cttaggcgga ggaaaaagaa agctagagct attgacacga atcgtagaag aaacagaaat
     2761 tccgatcaca caatttttgc ctactcatgc aaatcgcaca ccagaattat ttgaagcttg
     2821 cgtggcattt gccaaacgtg gtggcacgat tgacttcact gctagcgaag atcctgattt
     2881 ttgggagaag acagatggtg aagttcgctt cagcaaagca ctgaaacgat tgatcgagga
     2941 agatgtttct ttagataatt tcacgatgac ctcagatgga caaggaagct tgccttattt
     3001 tgatgaaaac aatcatttcc tagggttagg agtaggaagt gccaaggcat tgctagtagg
     3061 gatcaaagaa gctgtgcaaa aagaaagtat ccctttggaa atcgccttac gagctataac
     3121 cagtaatcca gcacgtatat tgaaattgga taaaaaagga aaaatcgaaa ttggtgctga
     3181 tgcagatctg tgtatcttgg ataaagaaac gcttgatatt gatacagtta tcgctaaagg
     3241 agaaataatg gtccaagaaa aagaagtcaa agtatggggg actttcgaaa aaagttttta
     3301 atcaacagct ctaactatct tttttagaaa acgagcgttc tgtttgtctg tatctgttgt
     3361 tgatgttacc ctgaaggtag atcaataaac aaactaagag gaggaagcac aatggcagat
     3421 ttaaaaggac gttctaaaga tatgaaagat aaagtagtcg gtgaaggaaa agaagcatac
     3481 ggcaaagcaa cagacgacaa gagcaaagaa acagaaggga aagcacaatc actaggtgct
     3541 gacatcaaag aaaaagctcg aaatttaggc gacgaagtca aagacaagtt ttctcgaaaa
     3601 gacgaaaaaa aataaaaacc acttattact aattgaatca agcaaataaa aaatccgaac
     3661 catatctgcg agacagatat ggttcggatt ttttatttga tcattatcct gttttttaaa
     3721 cttcgatttt ttgaaatttt ttatttttta gttcaaagac ttcatcacag ctttttgcta
     3781 cttcaatctc atgagtcacg atgataatac agcgattttg ttcatgggcg atttcttgga
     3841 aaagtttgac gatatcttgt gaagttgttt catctagatt tccagtaggc tcatccgcta
     3901 cgattagttg atgttcacag cagatagcac gaacgatagc gactcgctgc tgctgacctc
     3961 ccgaaagttt ggtcacctgt ttttttgcta atatttcatc aattcctaca cgagccagtc
     4021 gatctaaagc aacttgtcga taattctctt gcttggtctt agtgatttcc attgctgcta
     4081 tgacgttgtc tagagccgat aaataaggaa gcaagttgta agcttggaaa ataatcgaga
     4141 catcattttt acgataactt cttaacccga ttttgttcag tgaacgatct tgatagtata
     4201 cctttccttc ttttggtgca tctagtccag aaataagcga aagaaaagtc gtttttccag
     4261 aaccacttgc tcctaaaata gcgtacattt ttccagcttc gaaattcagt tctacatctt
     4321 tataaagcgc atcttgcgga tcttgatacc aaaatcccaa ttgttctgtc cgtaacatca
     4381 aattcctcct ttagtttaat aggatttttc ttgggtttaa tcttaatatc cctatagaag
     4441 ctaaaaagac agaaaacaga ctgattccaa atgctactcc ggctaatagt cccaattgtg
     4501 caggtttgac attgatttcc aattcgctga cttgatcaga aacagcaaat ggattattcg
     4561 tggttccttg ttgaccatcg cgttgaccgc cttgttcttg tctgttacct ggcatttgtc
     4621 caccgccagg agcttgctgg ttttgtgtcg tggtttctgt ctgttggtca agtagctgct
     4681 gtcccacggc attcgcgacg acgtttccgc taagcgaagc aactcctaat gcaagaatca
     4741 tacaaatagc cacttcggta aacaattgga gaatgatttt acttctggat tctcctaaag
     4801 atagcaagac gcctaactca tgccgacgct cccgaatggt aatcataatg atcagagtaa
     4861 gtatgataat accggctaca gccactagta aaacaacatt tttagaaaaa cttgccacgt
     4921 tgtttaaagg ttccaacatt gactgataca tggaatcatt tgattgtaag ctaaatgtat
     4981 ctgtgtcgat cagcttctca gcttctttga gaaactcatc cattttatct ggatcagata
     5041 gagtgtaaat agcagaatct atcgtgttat cgtcagatgt cccatttagt tcatttgcaa
     5101 aagtgtaaga agtgtaaagt gtattcgacg gattcatgaa gttgaatttc atacccatac
     5161 tgccgcttgt ttcgctggat tcataaattc ctttgatcgt catttcataa gtggtatctt
     5221 catcttcagt actcgtgatt gtgaaagtat ctccgactgc caggtcattt gtttctgcta
     5281 gagtagaatc aatgactaca ttgtttgtgc ctttgtcgct gtcatctatt ccttcaccat
     5341 ccgtgatttt tgctgttcca tcagaaaaat tactattttg tgcagttgct gacacaccac
     5401 tgatttgaaa gtctgcttga gtcatttgcg gattcccgcc cattcctcca gcaggttcac
     5461 cgcctgcatc agtagtttct gaactgtctt cacttgaatc agaactagtg atggcagtta
     5521 ttccatcttt tgccatagct gaggcggaac tttcaaagga ataactcttt acattatcta
     5581 attcagctat tttttccgcg tccgttaagg aaactggtgt aagagaaaaa ctgcctggat
     5641 ctggacgttc ttcagtggta gaaccgcttg aagaagtttg ttcctgtttt ttaaatgaag
     5701 cttctcgatt ggcacttaaa gtcactgttg ctccaacttc tttttgtgct tgattcgctg
     5761 cttcttctgc agcgcttcga atcgtgaggc cagctagcac aaaaataaga atggctgtga
     5821 acacggcaaa caataacaat gaacgtcccc attttacttt tgtacttttc catgcacgtt
     5881 tcataaaatt catattttgc atccctccta gtagatgcat ttgataatag acaacctatc
     5941 ttaaagctag cttaaatctt atgctgtttg cacaccatca acatgaggtt ctgtatatat
     6001 aaaaagtcac tatagttatt gcaaaaaatg tggtaaaatg aaaaaagtat gtttcaaacc
     6061 gacgaagaag aaatgaaaga ggaatagcaa aagaaatcct agatgctaca gagggatttt
     6121 tacgtgcata gttgttctaa caattgctga tactagcgat ttagtttatt tgttgtataa
     6181 taatggggaa cagctgaata cttatataag tattctggct atagcgtttc gcaaaagatc
     6241 cattttgtta atgaagtata tccaaaataa aatgcccatc caactgtcag aacgcggatg
     6301 tgctggtaat tttcctgctg attctccata agttgagaaa tagtgatttt gcatatgctt
     6361 cattggaatg gctcatatat ttagataaag aagaaaatcg acatctttaa acttggatgt
     6421 cataagaaga ggtgaagttt gtgagtacca ttaaaattat cccattaggc ggcgttcgtg
     6481 aaaatggaaa aaacatgtat gtcgcagaag tgggcgagga tatttttatt ttagattgtg
     6541 ggctaaaata tcctgaaaat gagttgttgg ggatcgacgt cgtaatccct gattttacgt
     6601 atttagaaga aaacattgat cgtgtagctg gtgtcttttt aacacatgga catgcagatg
     6661 cgatcggggc acttccttac ttgttgtcaa aaatttctgt accagtattc gggacagagt
     6721 tgacgatcga gttagcaaaa ttgaatgtca gtcgtaatga agcagccaaa ggatttaagg
     6781 atttccatgt ggtagatgag catacagaaa tagactttgg tgaaacagta gtgagctttt
     6841 tccgtaccac tcatacgata ccagattcag tggggatcaa tctgaaaaca aaagaaggta
     6901 gtatcgttta tacgggagat tttaaatttg accaaacggc tatcccaatg tatcaaacag
     6961 attatgcacg attggcggaa atcggcaaag aaggagtctt agccttacta agtgaatcgg
     7021 caaatgcaga aaatcctcag cctgtagctt ctgaagccca aatagcagat gaagtatttg
     7081 atacgatcaa atattgggaa gggcgtatca tcgtcgcttg tgtagcaagt aatttgcaac
     7141 gagtgcaaca agtattggat gcagcagaaa aagcacaacg aaaagttgtc ttgactggtc
     7201 aagatttcga acgaattatt cgcacagcga tgcgtttaga aaaacttcaa ttaccaagtg
     7261 aagatctgct tgttacgttg aaagacatga aaaactatga tccagaagaa ctgatcattt
     7321 tagaaactgg ccgaatgggt gaacccatca agtctctgca aaaaatggca aacggtacac
     7381 accgtaatgt caagattgaa gaaggagatt tggtttatat cactactacg ccaagcatcg
     7441 cgatggaaac catcgtggcg aaaacggaag atatcattta tcgagctggt ggaacagtga
     7501 agttgatctc tgagaatatg cgcgtttctg gccatgccaa tcctaatgac ttgcaattaa
     7561 tgatcaattt gatgaaacca acatattttg tgccagttca aggagagtat cgtgaattag
     7621 ctgctcatgc agatttggct catgcagtag ggatgccata caaaaatatc tatattactg
     7681 gacgcggaga cgtgctggaa tataagaaca agcgtatgag tgttgcagga actacaagtg
     7741 cagaaaatgt aatgattgat ggattaggca taggtgatat cggaaacatt gttttacgtg
     7801 atcgaaaaat cttgtcagaa gacgggattt tcgtagcggt tgtcactatc agtcggcgag
     7861 aaaagaaaat catttcaaaa cctcaaatta cttcacgggg attcgtttac gtaaaagcta
     7921 gccgtgatct gatgaaagaa agcagcaata tgattgaaac aatcgttgag aaacatttag
     7981 aaagcaatga ttttgagtgg agcaaattaa agcaagacat ccgagatcaa ttaggccgtt
     8041 acttatttga acaaacaaaa cgccgcccag tgatcttgcc agtcattatg gaagctactc
     8101 aacgtcgaaa taaaaaataa acaaaaagag taagatgaac ctctctatag agtgctcgtc
     8161 ttgctctttt tttgcgaaaa acaaataatt tttgaataca gcatccctcg ctttataata
     8221 aacgatagaa taaagggagt gaatcaatga tgagtcaaac aaaagtcgaa cgttatttag
     8281 aagaacaaaa gatcagctat caaccacttg attttagtca tgtggtagaa gaatctttca
     8341 cagaagaact acaaaaaaga gggattgatc cagctttgat atgtaaaact ctcgtagtga
     8401 aaggaaacaa aactggggtg atcatcgcat tgattccttt gaacgatcac ttagattaca
     8461 aaaaaacgag acaagtgacg aaagatcgta aagttggttt tcctggaatg gattttgtat
     8521 taatgcatac aggatatccc cacggagcaa acacccctat tggaataaaa ctcgcacatc
     8581 ctgattattg ttttttagca gacagttctt taaaagaaaa agaagaagta attgtgtcaa
     8641 gcggtgaaat cgggagaagc cttcggataa aagtagccga tttagaaaag atcgtccatc
     8701 ctatttacgc tgatttaatt agttaaggga cgagaagaga agctaagcag agcagagacc
     8761 tcaaacttga gattatatct gcttggtact tggtgcatcc tgtattatct gttacaattg
     8821 ctttgtacat actgtactat caatccaatg aaaatatatt tagcagctat attttttcat
     8881 tgatgtgcaa gtgatgaaat cgtttttaat aaaaaagata cagagaaaac gcgaggtgta
     8941 aaatatgaaa attacgtatc atggacattc ctgtttaaca attgaaatgg aaaatggcca
     9001 acgcgtgatg attgacccgt ttattacagg aaatccattg acagacttaa ctgcagaaga
     9061 agtaaagaca gattggttgc tgattactca tggtcatagt gaccacatag gagatatgat
     9121 tcctattgca aaagaaaatc aagccacaat tatcagtatt gttgagattg ctgattatgc
     9181 gaacagcaga ggagtagatt cattcggtat gaatatcggt ggaaaacatg cgtttccatt
     9241 cggcgtggta aaattcgtac atgcacagca tagttcaagc tatgaagtag acggtatcgt
     9301 tcagtatatg ggcgagccta gcggaattat tattcaagca gaaggaaaaa cgatttatca
     9361 tgcaggggat actgcttatt tcagtgatct aggattgctt gcagaagaat tcgatattga
     9421 tgtcgctttc ttgccgattg gcgataacta tacgatgggg ccagaagatg cagcaaaggc
     9481 tgcgcaaaca attcgtgcca agaaagtagt tccaatccat tacaatactt tccctgtcat
     9541 tgaacaagat cccgaatctt ttgtagagtt actggaagat agtgaaggaa aaataatgag
     9601 cgtctcggaa acgctggaag tgtaggcaga aaatggcgac aaaacatgat ttgattttag
     9661 aatatattga aagtttacct gttggcaatc gaatttctgt aagaagcatc gcaaaagaat
     9721 tgaatgtcag tgaaggaaca gcgtaccgtg caatcaaaga tgcagaaaat gtcggactag
     9781 tttcaacaat tcaacgagta gggaccatcc gtatcgaacg caaattaaaa aaacatattg
     9841 aacgtttgac atttggcgag gtcgtcagga tcattgaagg ggacgtttta ggcggggcgg
     9901 caggattaga caaggtcttg aataaattcg tcatcggcgc gatgactaaa catgccatgg
     9961 aacgctatat tacgccagga tcactaatga tcgtcggcaa ccgggcggaa gtccaaaaat
    10021 tagcattgga agatggcgcc gcagtattga tcacaggagg attcaatacg actgctgaga
    10081 ttgcaaagct agctgatgat cttgaaatgc cgatcttacg cacctcttat gatacattta
    10141 cagtcgcaac catgatcaac cgagcgttaa gcgaccaatt gatcaaaaaa gatatcatgc
    10201 ttgtcagtga tatctatatg ccagctgaaa agactcatta tttgcagcag acagatacga
    10261 tttctgatta tcagcgtttg tcagaagaaa cgcagcattc gcgttttcca gtcgtcaacc
    10321 gccatcatcg tttgatgggg attgttacgg caaaagatgt tttagggaaa tcgccaaacc
    10381 agatcatcga tcgggtgatg acgaaagaac caatcagtgt aaagaaaaca atgagtattg
    10441 cctctgttag ccatcaaatg atctgggatg ggctagaagt catgccggtc gtttccgatg
    10501 acttgacatt ggaaggcttg attacccggc aagatgtaat gaaagcgatg cagcttgtcc
    10561 agcgacaacc gcagattgca gatacgattt cggatcagat atctggaaat atccatacga
    10621 ttgatactga ccgtgaagga aatcgtttgg aaaaccctaa gttcaaattc gtagtagcac
    10681 cacaaatggt caatggcgtt ggaaccattt cttttggcgt acttagcgaa atcatttctg
    10741 atgtcgcaca aaaaacaatg gtgatgaacc aaaaacgaaa tatcttgatt gaacaagtga
    10801 acctacatta tttgcggctg atccaattgg aaagcgaatt agacattcgt ccacgtgtat
    10861 tggaaatcgg cagacgttcc gctaaactgg atatcgaagt gtttattgaa aacaccatcg
    10921 tttccaaagc aatcgttgtt tgtcaagtaa tggaacgttc ttagaaagca ggagtgaaat
    10981 gacagtacag caagaaatag tagatacaat aaaaaaatac gataaaatca ttatccacag
    11041 gcatttgcgc cctgatcctg atgcattagg atcacaagta ggattagccg aactattacg
    11101 ggaaagtttc ccagaaaaag aaatacgtca agtaggtgaa acgattgaag ggcttcgctt
    11161 tttagcagaa atgcaagaag ttgaagatgt cttctaccaa ggagcgctag tcatcgtgac
    11221 tgatacagct aattcaccca gaatcagtga tcaaagatat cagttggcag aaaaactgat
    11281 caaaatcgac catcatccca atgatgaccc ttatggagat cttgtgtggg taaatacaaa
    11341 agcaagtagc tgtagtgaga tgattgcaga atttgctttg atgtttcctg aatctttaaa
    11401 gatgaacgtt aaggctgcac ggttacttta tgcaggaatc gtcggagata cagggcgctt
    11461 tttgtatccc tccacgacgt cccgtacatt agagattgct tcgatattga gaaattatcc
    11521 atttgatgca agtgctttga acagagagat tgaacaaatg ccgatgaaag tcgctaaact
    11581 ttccggttat ctttatcaaa atatccaggt ggatgaaaat ggtgcaggaa gaataatcct
    11641 tccgcaagaa attcttgata aatatggaat cgatgattca gagacagctt cgatcgtttc
    11701 acttcctgga gtgattgacg aagtgctggc ttgggggatt tttgttcagc agccttcagg
    11761 gtattaccgc gtacgtttac gttctaaggg gccgatcatc aatgaattgg ctaaacgcca
    11821 tcatggagga ggccatccat tagcaagtgg tgcgaatgca aaagatttag cagaagtaga
    11881 ggaaatctat aaagagatcc aagatatatg ccaatcgtat aagagcagaa aaacagaatg
    11941 atacttcgtt cgaaaacgtg ccttttgtag taaaaatcac aaatgtatct tttcaagatc
    12001 ttctttttcc gttacaatag tgctcactaa agattttaaa ggagaaagaa gatgacatta
    12061 ccaaattgcc cagaatgtgg ctcagagtac acatatgaag atcgaggctt gttgatttgc
    12121 ccagaatgcg ggaacgaatg gaacaaagaa gaacaagaaa ctgtcataga agacggatta
    12181 gtggtattag atgcaaatgg aaaccgtctg ttagagggcg atagcgtgac agtgattaaa
    12241 gacttgaaag taaaaggtgc gtcaggtgcc attaaacaag gaacaaaagt caagaacatc
    12301 cgtttagtag aaggcgatca taatatcgat tgcaaggtag aaggatttgg accgatgaaa
    12361 ctgaaatcgg aatttgtgaa aaagaattaa agaatattca aggtcttttc acattctttt
    12421 cctactacta atgataaaat aaagtaaacg aaaaggagtg aaacgaaaat gtatggttat
    12481 ggaatgtatg gttttttaga tccgacattt cttttggtca ttcttggatt agttatttcc
    12541 ggaattgcgt cagcgtacgt caatagtact ttccgaaaat acgatcaagt gagaagcaaa
    12601 aacaatgtga ctggtacaca agcagcacaa tatatattac aaagtcaaca gataaataat
    12661 gtcggtgttc aacaaattgc cggagatctc acagataact acaattcagg taataagatg
    12721 ttgagtttgt ctcaagcaac tgcacagtct acttcagttg ctgcgatagg tgtagcagct
    12781 catgaatgcg gacatgcggt acaagatgct tcgggttatg tcccattgaa gattcgtgca
    12841 gcacttgttc cagcagctaa ctttggttcg atgatttcgt tccccttgat tatggtaggt
    12901 gtattgctta gctggaactc tacgttaatc aatatcggga ttttcgcttt ttctttagca
    12961 ttacttttcc aattggtgac attaccagtc gaatttaacg cgtctcggcg agcaatccaa
    13021 attttgagtg aaggcggact actgacggaa gaagaagtac cgatggcaag acacgtatta
    13081 tttgcagcag cactgactta tgttgcagca gcgctttcga cattcctgca gctgttgcgc
    13141 ttgatcttat tgttcggcgg caaccgaaga gattaaaata aagaagttgt gaaatcagcg
    13201 ctttgatctg agctaatacc gagagttagc tgattgaata ccatttattg gctcttcgtc
    13261 aatgagtgtt ggtgaagaaa ttcaatagaa taatcgagat actcacacgg ctagacagct
    13321 atcttgtcta gccgtgttgt tgttctggct ttagtcagtt gggtagtgtt cttagttttc
    13381 ttgaaatatt ttcctcgata taaaaagatt cgttctcggt agttttgaaa gtttctaaag
    13441 ccataggcaa ttcgttttag tactttgata tggttgttca aacattctat agggccgttg
    13501 gaatagggaa ctcgcaacgc tcgtttgatt tctgttcgat atttcttgaa ggtcgtgaac
    13561 actggttgat agtgctctgg caactccttg tagtcttctt ttaggagcgc gacgaattca
    13621 ggaacatctt gtcttctgat agcggaaaga aaaacctggt agacttcgta gcctcgcttt
    13681 aaggagtcat cataatataa tagccgatcg actatctccg cttctgtcag atgatctcga
    13741 aatgacggac gccagtagcg atgctgacca ttcaattccc acgcattctt ttgaagtagt
    13801 ctccagtatt tctttaagtg cttcgaccga cgatcccctt ttttaaaggt cttcattact
    13861 tgaattcggt ggttggtaaa ggcccgaccg atgtgttggc taatatgaaa gcgatcggcg
    13921 acgattcggg cattcggaaa acactctttc accaatgtgc gatagggtgt atagaaatct
    13981 gaaaccacta gacgtacttg ttcacggact tttctagggt agcgcaagaa atagtcgcgt
    14041 aaaggattga gttgccgatt ttccacaata tcaatcagtt gatgggtctt gccgtccatc
    14101 atgacaaagc tcatggctcc cgagacgttt ttcaccgatt tgaattcatc gaaacacacc
    14161 acttctggta acggctggtt caaagaaacg gttttaggcc gaaggctgcg aagtattcga
    14221 atgacagtgg tcggagaaat gtgcttcata cgtgcaatca aagacataga aataggctca
    14281 cttaatagct caagaatggc ttgtttgact ctgcgggcaa tggagcagcg acgatcgcta
    14341 actgaatctt ctgctaaaaa agtctttcca cagtgtttac atttgaagcg ctgtttgtta
    14401 atccgcacaa tggtcttgta gttactgaca tcattcaata agatggatac ttttttccag
    14461 ccccatttaa tgatcgtttg cttattttga tagtggcaat ggaagcattc ctctggttga
    14521 taggtcaatg tgccatcaaa aacaaaacat gtttcgtcat taatgcgctc tttgcgaaag
    14581 gcatcttcat gaaaggtaag atttaggtct agaatatcta gtaactcttt ggtaaactct
    14641 gaataggaca tcttgaaaca ctcctttgaa tggttttcgt cgactttatt ctaaaggatt
    14701 tcaaggtgtc tgtttgcgtt tattagaaaa aagaaaaagt attg
//
LOCUS       DAZKPE010000069        14463 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000069 DAZKPE010000000
VERSION     DAZKPE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.069"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(287..649)
                     /locus_tag="ACG930_002280"
     CDS             complement(287..649)
                     /locus_tag="ACG930_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519432.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="ACG930_002281"
     CDS             complement(723..1103)
                     /locus_tag="ACG930_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFQ0519433.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="ACG930_002282"
     CDS             1185..2360
                     /locus_tag="ACG930_002282"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFQ0519434.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2437..3021)
                     /locus_tag="ACG930_002283"
     CDS             complement(2437..3021)
                     /locus_tag="ACG930_002283"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0519435.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3222..4220
                     /locus_tag="ACG930_002284"
     CDS             3222..4220
                     /locus_tag="ACG930_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0519436.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4332..4841
                     /locus_tag="ACG930_002285"
     CDS             4332..4841
                     /locus_tag="ACG930_002285"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFQ0519437.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4871..5530)
                     /locus_tag="ACG930_002286"
     CDS             complement(4871..5530)
                     /locus_tag="ACG930_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFQ0519438.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5532..6296)
                     /locus_tag="ACG930_002287"
     CDS             complement(5532..6296)
                     /locus_tag="ACG930_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFQ0519439.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6304..6981)
                     /locus_tag="ACG930_002288"
     CDS             complement(6304..6981)
                     /locus_tag="ACG930_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFQ0519440.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7018..8403)
                     /locus_tag="ACG930_002289"
     CDS             complement(7018..8403)
                     /locus_tag="ACG930_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFQ0519441.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8613..8697)
                     /gene="ffs"
                     /locus_tag="ACG930_002290"
     ncRNA           complement(8613..8697)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG930_002290"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="ACG930_002291"
     CDS             complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="ACG930_002291"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFQ0519442.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9342..10199
                     /locus_tag="ACG930_002292"
     CDS             9342..10199
                     /locus_tag="ACG930_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519443.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10280..10615)
                     /locus_tag="ACG930_002293"
     CDS             complement(10280..10615)
                     /locus_tag="ACG930_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519444.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10682..12052)
                     /locus_tag="ACG930_002294"
     CDS             complement(10682..12052)
                     /locus_tag="ACG930_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFQ0519445.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12130..12666)
                     /locus_tag="ACG930_002295"
     CDS             complement(12130..12666)
                     /locus_tag="ACG930_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0519446.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            12975..14456
                     /locus_tag="ACG930_002296"
     CDS             12975..14456
                     /locus_tag="ACG930_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519447.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4458 a         2877 c         2351 g         4777 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc ataataataa
     3061 taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat ttttcatcac
     3121 tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg agaagcattc
     3181 tcaattaaat tctgctatag tgtgaaaagg gaggaatttt tatggaaatc tatgacatta
     3241 caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga atgcgccaag
     3301 ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca actttgtatc
     3361 ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt gaattaatcg
     3421 atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa gaagaagttc
     3481 tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc atccattatt
     3541 ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa ttgaatttag
     3601 ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat ttgatgaagt
     3661 atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat tggacgttga
     3721 tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa tttcgtgcgc
     3781 acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact ccctatctca
     3841 tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa aaagtgaaaa
     3901 gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga ttctcttcta
     3961 atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt actgtaaaat
     4021 cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt acctatgaag
     4081 gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg aacaacgctt
     4141 tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc ttatacgata
     4201 aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa acccgaaagc
     4261 agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa aaataaaggg
     4321 ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga gaactattga
     4381 aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta caaaaagact
     4441 atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg ctaacaaagc
     4501 gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca gaaaagaaaa
     4561 aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac ggtatcgatg
     4621 agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg aattatggtt
     4681 atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat ggcgttcatg
     4741 tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc agtcgattag
     4801 cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa aaaagaaaga
     4861 aaacgtctat ttagacgagt tctttctttt ttgtttgttt caagctattt tttcctaaga
     4921 aaagaaaaac agcaaaaaat aattctaata atacaaaaaa taagataaag ctatgcatga
     4981 aaaattcttc tggaagtaca ttgatgattg gatcagtaac gggatcgaat aaccagtcat
     5041 cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg atcaaatcct atcatcatga
     5101 aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa cggacgaatc aaccgccaaa
     5161 gccgatcatt cttttgcaaa tatttgataa acaaaatact cgggatcaaa gtgatgaaaa
     5221 acacagcata atccactaaa aacaaaattt tcacttcata aaagtgatgg gctccgctag
     5281 cagaaactgg gaaatctggc aagctgagga tggttttgaa gggattattg agataattca
     5341 ttaggtgatc aaaatttttc agtaacgtct cttgatctaa agaagtataa tccaaaattt
     5401 gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt gatcgtcaca ccaactgcca
     5461 gactgatcag tgtcagaaat aggctgaaca atccagcata ttccatccac tgccatctcg
     5521 aatttttcat attagaagct ccattcatcc agtgattgtt tcacataggt agctgggata
     5581 ggcaacccag gtacatcttc ttcttttgta aaacctgata aaacgagcaa agtatctata
     5641 ttattgcgta tcccagcttg gatatctgtt tcatagttat ctccaaccat gattacttct
     5701 tctttttgca gccctaatac ttcaacggct ttatccataa tgatggcttc tggttttccg
     5761 atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag agatgactga ccctgctcca
     5821 ggaagaaggc cgcgttcagt aggtatattc ttatctgggt tcgttccaat gaaagtagca
     5881 cctttttgaa tagcaagtgt tgctttaact actttttcat aggtcagata attatctaag
     5941 cctaccacta catagtcagg agcctcttct tcccatgtaa atccggcagc taaaatcaag
     6001 tcaatcaatc ctgcttctcc gataacatag acttttttcc cttttccatc tgctttcata
     6061 aaatcgattg ttgccaaagt agctgtgtag actgtctctg gagctacatg aatgtcaaac
     6121 tcatctgcta gacgattagc tactgtttct ggtgacttag tcgtgttatt ggtaacaaac
     6181 aagaaaggta attttctttt ttgcaattct tccacaaatc gtttaccggc cggtatgggt
     6241 tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat atcctttata gtccattcat
     6301 ccactactct tccctttttc tgatcgtaaa tgctgttttt gttttttcta cttgtttagg
     6361 ttgttcttgt ttttttactt tttcagaggt ttttgctgac tctgtttttc gatttttaat
     6421 aaccggtttt ttgcgattag atgcgactgg tccttttttc tcatcgatat acgcacgatt
     6481 atggtttttt ttcttttttc ggcgctgagt tgtcttttct tttttaccgc cgattctctc
     6541 gatgacaaaa tacgcacaac caaaattgca atattcgtaa agatagtctt ccaaggaatc
     6601 gattcgctga tctggatgcg cccgtcgatt atccgcttgg aaaaatcctt ttaggcgtag
     6661 ttgttcataa ccccaatctc ctacgatata atcatatcgg gctagtacat cactgtaacg
     6721 ttctccaagc ttttctgcat taaatccttc acgataatcg gacacaagcc gataatgtct
     6781 ttcacctatc aaaaaattac tgtcatctaa cagtgtcact agctcgcctt tgactttttc
     6841 tgctttaggc tcctcaacga tttcttccaa agcagctgtc agttcttcgg tgactgttgt
     6901 ttcctgttca gctgatgatt ttttcttagc aatttctgtt ttatgctcaa cgttctgctg
     6961 ttcattttgt tttgcagaca tgcgttcacc acctatcttt tttattatac cttgttttta
     7021 tttgattggg tagtgagctt tcaagtaatc tcctaccaca cttcggataa attcagggaa
     7081 caaaaattca ttttttccag caatctcaat cgttggaaaa aatggaacaa acatcaaatg
     7141 atctacggta gtaaaagtat aatttttatt cagatcgatt ggcttgttct tccaaaagac
     7201 ttgatggtta atagaatcat atgtgattcc attatagacc atctgcccaa aaatcttacc
     7261 gcgaaatccc attcccttca taggatagtt acgtaaaaag ttacgatttt tttctatttc
     7321 taaaactaag cggatcagat catttccacc caatgtgaca tttaacaagt gcatcggatg
     7381 cggcaacgca gtgtgaagct gatcctgatt gacccgccct tttggaattt cagttaaaaa
     7441 cagaccactg tttaatattg ctgcttccgt ctttcctcgt tctttcaccg cctcaaaggc
     7501 tacttggata aacgaatgct cattgaagat atctagactc agagaaaatg gcaaatctgc
     7561 tacttctttt tcttttaata attcatgccc acgttctaga taactattta tttcttgttc
     7621 atcttctgta aaagctgtca ttgtttcggt agggatggct ttggctgaat gcttaaggat
     7681 ttttttctct tcatcgatgg ttaaatggac ttcaccgaca tactgcccgt actttccagc
     7741 ggctgctatt tggacatcat tgattacgtg accttctctg aataaatgat gggtgtgcga
     7801 tcctaaaata acatcaattg ctggtatttc ttttgcaatt tggaaatcat cctgaatccc
     7861 gagatgactc atcaaaacta aaacatccac ttgtgaacgt aaatcttcga ctaattctgg
     7921 caaaatatca taaggattcc gtatgtccca gccattcgga ttataagtaa gcggaaatgg
     7981 agcagtaaat gcaattagtc cgattttcgt ctggtgtttc gttgtaatga ttttatatgg
     8041 tttcgtccat gccggtggct ggagcgtatt tttatcgaat aagttatcca ggatgatatc
     8101 aaactcagca tgatcgtata aatgattcaa ctcttctttg gaatttccta cgccttcatt
     8161 gtttcctatc gtcgctgcat cataaccaac ttcattcatc agcaagatat tttcctgtcc
     8221 attcgttgct tctgacaatg gatgccaacg atccacaaaa tcacctagat ctactgcaat
     8281 cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt tgatccaaaa accttctgat
     8341 ccttggccaa ttttctaaat gagaatgcag atcattcgta tgtaaaatca ctattttttc
     8401 catgtaccct ctcgcctctc tttatcttta tcataccata ggcagctttt tcttccattg
     8461 aaacaagctc tatttcagag tttttcctgc cttgaagcaa attgtataag tacaatattc
     8521 gataaatcag tctggctaaa aaatcaggaa cattcatttt tacagtacta taaaaataaa
     8581 aaaaacagac ccgaaagtct gttgtcgttt cattataatc agacacatgg cggaacctgc
     8641 ttagtgctgc ttccttccag acctgacacg cttcacaagc ccaccattgt cctagccttt
     8701 cggcaaagaa tagtatacct tatttttcat tcgttgacca gtcttttttt aatttctttt
     8761 ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat cccacattcg tcttctaaaa
     8821 tgccaccttc tacatatgct tggtggttaa accgctcgtc ctccaaaaga ttcatcaagg
     8881 taccggctgt tccgcctttt ggatcatacg cgccgaaata aacttctgct acacgagaca
     8941 aaatcatcgc gccgctgcac ataggacaag gctctaaggt aacaaaaagt gcagcatctt
     9001 ccaagcgcca gcttcccact ttttcacagg cttccttgat tgcaagcatt tctgcatgtg
     9061 tagtagcatc ttgcgtggtt tctctaaggt tatatcctct tccaatcact tttccatcca
     9121 atacaaccac tgctccaatc ggaacttcat gaagcatttc tgctttcttt gcttctgcca
     9181 atgcaaggcg catccatttt tctttttcta ctgcatcaag atttgtattt accaattacc
     9241 cttccctgcc tttgtttttt cttgttttac tttagcatat gataaaaagg ctgtaactaa
     9301 cttttttttc tatggtaaaa taaatacaag aggtgaacaa gatgaaaatg gataaattac
     9361 ttgctcttta cccacaagca cagaaaaaaa actctccagc atcagaagcg gatatccttt
     9421 cttttgcaat tgatgatgct tttatctgga tcaaacaaga ttcattatct caacaagaaa
     9481 ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca aaaaaaacac ccatggtatc
     9541 actatctttt taaagatgct tcttgtgttc aagaaaaaag ctttcgtttg atccagcttc
     9601 acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca agatactatt ttggaattat
     9661 ttcgctattc tgctgatttc tttttttata cagacacaga tgcgctctta gtcgaacaaa
     9721 taaaccgtga ttatcttgat gctactgaaa tcaacggtat ttttctatct ttagatgctg
     9781 attttgatac gacaacgtct gtattcgttg gttctttcca ttcacctggc accgacctcg
     9841 tccctttgtt tgctgaagaa agaaaaattt ttttaacaga gcaaaacaat ctttatactc
     9901 acagccgtac tttttctatg caagatgtgg ctttacatta ctatacaaaa gatactgtaa
     9961 aagatagtaa gttgatcaaa agttacatag aactgatcaa acaaaatgaa atggaagtga
    10021 tcattcaaga attatggaat gaattaggca atgtcagctc tgctgcaaaa acactgtttc
    10081 ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca agaacagtct ggtttcaatc
    10141 taaaaaaagc caacgattta ctgttttgct atcttttatt gcttcatgaa cataattaaa
    10201 gatagattaa aggggttgtg acaataattt tgtcacaacc ccttatttcg aatgaatagt
    10261 gttcaaaagc tagtttctct tacatcattt tttcaacaaa atgcattagc cggtctttta
    10321 catcttcggt tgaatctttg attgaatcac cataaacaga gattttcttt tttcctgatt
    10381 tgatttttgc taacattccc atcaaagaat ccaagtcact atctgaaaga ccatctacga
    10441 tttctagtaa tttttcattt ccatcaaatt tgtcatagac gaattttttt actttcgtcc
    10501 gagtagtcat atgatggatc ttttccatta cttttcccga tacaacgact gctgtcgcta
    10561 cactggcagc ggctgctacg cttaatccga ttgttacttt tgttgatgtt ttcataagta
    10621 tcagctcctt tttatctatc tccatcatag catagacaaa aaaataaacg aactaatcca
    10681 ctcagtgaaa tctcaatcct ttagggaaaa agttctttac tgttcctttt acttgtttcc
    10741 caaatccgac aggtatctta tctaatacta gcaaaaccca tccttgattc ccatcacgtt
    10801 gaaatgtttc tcctgctgtg taagattgcc attccttttg agtgatcggc aagcaaggta
    10861 tattctctat cttttttgta gcaagcgcta atgcatagct aggttcaaat cgattctttt
    10921 tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa accatcgaga gaaggggcta
    10981 actcaggaac ttcccaaaga tggtcgttga acactaaaag tcttccagta gcttcataat
    11041 gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc ttttgtcatt tgcactttac
    11101 ttttttttcg tgtcttcttt tctttatgca tctgattttg tccatgaaaa gtcagctttg
    11161 caacaaaatg tccttcaccc tgatctttat gaggccatat acgtattgtt ttttccaaac
    11221 cagctacgct tccccattca gaacgtcctg aactaacgga ttgagtcaaa ggaatctcct
    11281 caatcgttac tggataattt tctacaagcc agctaatgat ctcttcattt tcttctggtg
    11341 caaacgtaca agtcgaataa atcagttgtc ctttattttt tagcattttt attgctgaag
    11401 acaaaatctc ttgctgacgt ttttgacagt atagcggaga ttcttctgtc cactctttta
    11461 ttgcatttgg atcttttcgg aacattcctt ctcctgaaca aggagcatca accacgatcc
    11521 gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg tgcatgattt gtcactattg
    11581 cgttcgaaac tccccatcgt tctatatttt ctgataaaat cttcgcacgt ttcggaaaga
    11641 tctcattcgt cactaataac cctttcccct tcatttgagc agctaattgg gttgatttac
    11701 caccgggagc cgcacacaaa tccaaaactt tttcaccggg ttttgctgca gcagctgttc
    11761 caacgatcat tgcacttggt tcttggctat attcataccc agcttgatgg aggaaagact
    11821 ttccattgac agtgccaaga aatccctcat tgctgtaggg agcgggttgt aattcttcgc
    11881 tatggtaagt ttggaccatg tccaatcctg ccggttttag tggattccac cgaaatcctt
    11941 ttttcacgct tccttgttca agcgcagaaa aaaaatcgga tgcttcttcg cctaaaagaa
    12001 gacgatattt tttgataaat tgctgtggta acgttgtcgc ttcctccttc attccaatgt
    12061 ttcgttagac attttacaat cttttttacg aaaaataaag gtggctgatc tactttttca
    12121 tgttgctgcc taaggtgact gttcctttaa gatattttcc aagtattcat ccgtcacctc
    12181 gtttttatcc caaacagcgt tcatcatttc aagaaaatct tgagaagaat catctgagcg
    12241 caaacttccc aatgcattaa gccataccaa ttcaagcgac ttttcttctt tgatcttcgt
    12301 gtgacctttg acatatgaga aaaatggccg cttaaatagc gaatccatgt ctaaatcaga
    12361 ttttgcaatg atttcacgaa tactttcatg gatagaaaaa aaatctttca ataagtagac
    12421 aatgcttaaa acatcatcgg aactgcattc agctaagtag ttttcaaaat aaacagtgat
    12481 ttcttctaat atcttctctt ttaacccgct gattgatttg aaatgtgtat aaatcgggta
    12541 tgtagaacaa ccgcagaact ctgctaactc tcttgcagta attgacttca ttccatattc
    12601 ttccacgtat accatacttt tgaacagcaa atattcttta ctataatttg ttactctccc
    12661 catcattctt acctccgtct cttttcatct acccataaat aaataacata aataattcta
    12721 aaaatattat tgataattat caaaacatat ttagttatat ccattaaaaa tcaatttttc
    12781 cgccttaaaa acaagaatat cttgacaaaa taccctagga aataaacaat agaataaaca
    12841 aggtaacaaa aaaattaaat aacgttatat aaaaaagaag gcgacactct gtgagaataa
    12901 cacagactga aatgactttc cactcacagt ttttgtctaa ctatatacaa aaacagaata
    12961 aaaaggaggt atttatgcta attgaagcaa gaaaaaaaga gttacttgtt ctacaaatgg
    13021 tcattcaaaa aaataattgt tctttacaag aattatccaa tgacttacat attccaaaac
    13081 ggacaatcaa agaactgatc cgaaaaataa atgtatcact caagcaattt ttattgattg
    13141 atgaatttat ttattctaat cataaaggag agatccaaac caaagaaacc gatcaaacta
    13201 aaaagttagc tgttttttct aagttaaaat tatgctacct aaaagaatcc aatcgtttta
    13261 actatttgat gttactaatc aattatccac aaactgctgt accaaaaaaa tatttacttg
    13321 aacaacttta tatatcgccc tcctatctcg aaaaactgac aaaacagctc aatcattcct
    13381 taataaaatt ccatttacgg atcctatctg taaaaaattg ctgtactctt gaaggaaatg
    13441 agttatctat ccgtctctat ctttactttt ttctttcaga tacatttgga ggtaacgatt
    13501 ggccattttc ctcacttgaa ttaaatgcac taaaaatgaa cagtacagat gagcaaatag
    13561 aaaaaatttc aaaacaagaa aaaaatatct acttgctgtt aactttattc atattacgaa
    13621 acaaacaaca ggcatatttt ccaaaaactt cttctgaaat cactgaattg atggacttat
    13681 tgcagcatac acatgattat tcagaatact ttacttcttt ttcagtgagt cgcccttgtg
    13741 aagagacaga aacagagaga gcctacttta attatttttt ctattgtttt tttccaaatc
    13801 aaatctcttt tcgacaaaaa caggagattg gttttttatt ttccacaagc aaaaacctta
    13861 tttgtcgaca agtcggtcaa ttgatgactt acttaactca acagtttcct ctcaaccatt
    13921 tagaaaataa aataccaatt tatttttatt ttcttgtgtt ggcagttgtt tttttcgaac
    13981 tgttgggtga atccagcagt agtttttcta cactttgctt tccagaagcc acgtccaatc
    14041 attctagttc ttttatacag gaaaagaaat taagagaaaa aatcgataca attttttcaa
    14101 aaaatgggga aagaaaccaa atcagtcaat accttagtca attgatccaa cacttactac
    14161 aaacagaaac gaaagagcag ttactcatcc atttgcagat aaccaaacag tttacaggaa
    14221 attatcatct tcaaagccat ttgcagcagt tatttcgcaa agatgctgtt aaaattaccg
    14281 catattcaga acatgctgat ttgatcatta cagatcagca tgagaaaatt tcagatgaaa
    14341 cggagacttt ctatctggat acaacgcaca atacagtgtt atttggcaag ttaataaaag
    14401 cggttcatga actgtatatg aaaaaaggtt atgagaacaa aacaaagagg atgtgacaaa
    14461 att
//
LOCUS       DAZKPE010000070        14389 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000070 DAZKPE010000000
VERSION     DAZKPE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.070"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..2377
                     /locus_tag="ACG930_002297"
     CDS             5..2377
                     /locus_tag="ACG930_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFQ0519448.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAESGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVTKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFSLGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="ACG930_002298"
     CDS             2438..3898
                     /locus_tag="ACG930_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFQ0519449.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERSNGTYDFDRFYQGKGDINAQILFSYKAEQYYKGYKKHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /locus_tag="ACG930_002299"
     CDS             3909..6113
                     /locus_tag="ACG930_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFQ0519450.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSLLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESYRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYHKAAACTSEACDFRLWTTIAKKKLTATQLKEII
                     QNGRTSQPVKGLKGQKGSFEATIVLKEDFTTSFEFSEKKKTNYKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="ACG930_002300"
     CDS             6129..6278
                     /locus_tag="ACG930_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519451.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6359..6955
                     /locus_tag="ACG930_002301"
     CDS             6359..6955
                     /locus_tag="ACG930_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFQ0519452.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYSKAEWYELGKIEIKSRYGNPVIAYDPERTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTIRSYIMALN"
     gene            6968..7867
                     /locus_tag="ACG930_002302"
     CDS             6968..7867
                     /locus_tag="ACG930_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFQ0519453.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFENRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYEETMDSISNLMEKVI
                     HVEEKERKIAYQRHQQMNREMER"
     gene            7870..8355
                     /gene="ssb"
                     /locus_tag="ACG930_002303"
     CDS             7870..8355
                     /gene="ssb"
                     /locus_tag="ACG930_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0519454.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGILIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8721..8981
                     /locus_tag="ACG930_002304"
     CDS             8721..8981
                     /locus_tag="ACG930_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519455.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="ACG930_002305"
     CDS             9428..9634
                     /locus_tag="ACG930_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFQ0519456.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9634..9858
                     /locus_tag="ACG930_002306"
     CDS             9634..9858
                     /locus_tag="ACG930_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519457.1"
                     /translation="MKTQHKLLNVKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFE
                     DLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            9873..10310
                     /locus_tag="ACG930_002307"
     CDS             9873..10310
                     /locus_tag="ACG930_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519458.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEAGVKPSTIKPSEYQALE
                     LTYGKFIETKKAKTVSSEWLDYFENVNKYGACYIMKKEDNENE"
     gene            10303..11010
                     /locus_tag="ACG930_002308"
     CDS             10303..11010
                     /locus_tag="ACG930_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519459.1"
                     /translation="MSNVVYQLTVEDVSHFLTNKEHLNEVVRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDCKRMPYQRFERKKGQ"
     gene            11175..11375
                     /locus_tag="ACG930_002309"
     CDS             11175..11375
                     /locus_tag="ACG930_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519460.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            11391..11570
                     /locus_tag="ACG930_002310"
     CDS             11391..11570
                     /locus_tag="ACG930_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519461.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQELKQKYGKSESRIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            11663..11848
                     /locus_tag="ACG930_002311"
     CDS             11663..11848
                     /locus_tag="ACG930_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFQ0519462.1"
                     /translation="MPLTGKEMLKLLKKNGWVERRQEGSHHHLYKDGVRITVPVHANQ
                     DLGRGLEQKILKDAGLK"
     gene            11882..12313
                     /locus_tag="ACG930_002312"
     CDS             11882..12313
                     /locus_tag="ACG930_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFQ0519463.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
     gene            13250..>14389
                     /locus_tag="ACG930_002313"
     CDS             13250..>14389
                     /locus_tag="ACG930_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide MFS transporter"
                     /protein_id="HFQ0519464.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGI"
BASE COUNT         5209 a         2383 c         2966 g         3831 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaag
      121 aaagaccaac ggtcaaccaa tgaacgataa gagaaatggg cattcttggt ttaggcaaca
      181 agagcgaatc gaaaataaag tgcatagtct gagagaagag atcaagcaac aagaaaaaca
      241 ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgc
      661 accaactgat tctctgaagg agaaagaaaa agatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tagagttgat
      781 cgatcaactt aaaacgttgg ataaccaata cgctgcagaa tcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgttacg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 ggacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcatgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat tgaagtgatc aaaaaacctt actacacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca attgaagcct gaagactatc cgaaaatctt
     1501 cccgaaccgc gtctttgatt ttcaattgga taaaacaggg cagacagaac ttcaagttgg
     1561 gattcaagcg gtagccaaaa atattggaat tcaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtacgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctgtagaaac ggcagaacaa aagaatattg ttcctgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtga ttttaaaagg
     2221 aaaaagttat ggaaaagaga ttcaaacggc gttaccttca gaagaatttt cgctaggaaa
     2281 tccattccga ttttcacttg aaacagtgtc agaagtggcc aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg tttgaaaatg accgaaaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ctctaagcaa caatttaaag cagccacaga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtagaa aatcttcatt ttgagacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaac atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaat gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagttaaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtttcga tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagttga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaagtcattt atgaagaagt cgcaaaagaa gaaaagatca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaat tggtttccgc
     3541 tcacaaagta aatgcgtctt ttggtcagca gctttctgtt aacgattcaa tagaagctat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagcttgtg aacgctcgaa
     3661 tggtacgtac gattttgatc gtttttatca aggaaaaggg gatattaatg ctcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aagcatgaac atgaatttgt
     3781 acctgaagtg aaaaaggatt ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 tagaaagcaa aaacgtgcga tgttgtttca acaaggcaga caacaagaaa gggagtgaga
     3901 tcgtcacgat gaaaactgtc attttagcag aaaaaccgtc acaagcgaag gcttatgccg
     3961 atagcttttc taaagccacc cgaaaagacg ggtattttga gatccaagat cgattgtttc
     4021 ctggtgaaac tgtgattacg tatggttttg gtcatttagt cgagttagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt acctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa cgtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg cgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagca ggcgccgatc atggaaagat atttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagat gcagaagaga
     4381 cctacccaaa atttgaagaa gcacaagcac gccagatcgc cgattggttg atcggcatga
     4441 acggtagcct actgtatagt ttactcttgc agcaaaaagg cataccagga agtttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attacaggaa aagattagaa
     4561 acttccaaaa agaaccatat tttgaaggaa aagcccaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggtac gatccaccaa gttgaaaccg
     4741 agaaaaaaag tgcggcaagt ccacgtcttt tttctctatc cagccttcaa tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagata ctttggaagc catgcaaggg ttgtatgaag
     4861 gaaaatatct aagctatccg cgaacggata ccccttatat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttaaa agccgaagcg attccgactc
     4981 ctattcatac accgaatagt cggtatgtga ataataagaa agtccaggaa cattacgcga
     5041 tcattcctac aaaaacggtt atgacagcag cggcttttga acaactaagt ccactgcagc
     5101 aggctattta tgaacaagtg ttaaaaacaa cggtggccat gtttgcggaa aagtatacct
     5161 atgaagaaac aacgatcttg acgcaagttc agcagcttca gctaaagaca gtcggaaaag
     5221 taccagtaga tctaggttgg aaaaagctgt ttggcaaaga gagctacaga aaagaaaagg
     5281 aagaagaacc gctacttcct aaagtgacaa aaggagaagc ggtgacggta gatctacaag
     5341 tccttgaaaa agaaacgaag ccaccacaac cttataccga aggtacgttg atcacagcga
     5401 tgaaaacagc tggaaaaacc gtggatagcg aagaagcaca atccatattg aaagaagtag
     5461 aaggaatcgg tacagaagca acacgagcaa atattattga aactttgaaa caaaaggaat
     5521 atatcaaggt agaaaaaaat aagcttgtgg tgacaaataa agggatttta ctttgccaag
     5581 ccgtggaaaa agagccgctg ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact
     5641 tattaaagat tggtgagcag aaaggaacac aagctacttt cttagctaat atccaaaaat
     5701 ttgtctctca cttgttggaa gtcgtaccag gacaaatcca atccactgat tttggatcga
     5761 cgttacaaga ggtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttagggattt
     5821 gtccaaaatg ccaggaacaa gaagttttac tctatcataa ggcggccgca tgtacgtctg
     5881 aagcttgtga ttttagatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggaaat cattcaaaat ggccgaacaa gccagccagt gaaaggatta aaaggtcaaa
     6001 agggttcgtt tgaagcaacg attgttctaa aagaagactt cacaacgagc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac tataagaaaa gaacacgccg cactacaaaa taatggaggg
     6121 gttatcttat gcgaaataca acacacaaac aacaagaaat cgaaaatcaa aaagcaaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa attgaattag atcgataaaa tcttcctggc tattgtatac
     6301 gcataaactt atgttatact atatttataa gtttatacgt atacaaagga gggagaaaat
     6361 gacaaaagca atggtttaca agctgctaga agaatttaac ggaactttgg ctttgaagga
     6421 tgccaaaaaa gcgggcattt ctcctgtaac gatcaaacgt atggtagatc gtggagagct
     6481 ggatcgtgag tatccaggtt ttttcacctt acctggtcaa tttcctgatg aattgtttat
     6541 ggcacaaaag aaatatgagc gcggcattat ttcgcatatc accgcgttgg atttatatga
     6601 tttaacggat atgatcccta gacagatcga tctaaccgta ccttacggtt atcacgtttc
     6661 tgaaaagggg ttgaaagaat tcgcagttga gttacactat tcaaaagcgg aatggtatga
     6721 attaggtaag atcgaaataa agagtcgtta tgggaatcct gttatagctt atgatccaga
     6781 aagaaccttg tgtgacattt ggaatccctg gtacaacgtt gaggatgaaa tcaaagtaaa
     6841 agcaatcaaa aactacatgg agtcggacag aaaaaatctt agaaaattga atgagtatcg
     6901 acgaattttg cctacagaca aaacgatacg ctcttatatt atggctttaa attaaaggag
     6961 aagacacatg acacctacgc aattaaaagc aaaagtgaag aatatttcca gagaaaaaga
     7021 agttgatccg cagcttgttt taagacattt tatgatggaa aaattcttgg aaaaaatctc
     7081 agagtctcct tatcgtgaaa attttgtgtt aaaaggcggc ttcttaattg gctcaaagta
     7141 tggcattgaa aatcgaacaa caaaagacat tgatacgact ttacgggaaa tgaaagtaac
     7201 caaagaaaca ttgacaacgg ttctaaacga tattttttca acgccgacga aagaaggcat
     7261 tcaatttgag attcaaggaa tgaaagaaac aagggaagct gattattatc cagggtttag
     7321 cttacgtgta ctggcacatt tggaaaacat gcggccagat tttaaggtag acgtgacgac
     7381 aggtgactcg atctatcctg caacgatcac tcacagtcat aaattgatgt ttgaaaatcg
     7441 aacgattcct ttggaatctt atcctacaga acaaattatt gccgaaaaat taagtgcaac
     7501 ctttgatttt ttaacagata attcgagagg aaaagatttt tatgatctct atactattcc
     7561 taaaatggaa aagatcgatg agaagacctt gaaagatagt gtgagaaata catttacacg
     7621 tcgaggaaaa actgatccgt taaagattta ttacgaaaag gatatggatg tactgaaaaa
     7681 tagtcatgag ctaaaagata cctggaagaa atatcaaaaa agcaatcctt atgctgcgtc
     7741 gatcacgtac gaagagacaa tggattcgat tagtaatttg atggaaaaag tgattcacgt
     7801 cgaagaaaaa gagcgaaaaa tagcttatca aagacaccaa cagatgaaca gagaaatgga
     7861 gagataaaaa tgatcaataa tgtaacttta gtaggacggt taaccaaaga tccagattta
     7921 cgttataccg caagtggcac agcagtggct acttttaccc tagccgttaa tcgtaatttc
     7981 acgaatcaaa acggcaatcg agaagctgat tttatcaatt gcgtgatttg gcgcaaacca
     8041 gcagaaacga tggcgacatt agctaaaaaa ggcatcttga tcggcgttgt cggacggatt
     8101 caaacacgga cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtagct
     8161 gataacttcc aactattaga aagcaaagca gcgacagaga gccgtgcgca cgctgatcaa
     8221 tcgtccacga gtccaagcac caccactttt gaacaacggg atacagcgac gcctaacaac
     8281 aatggattga acgcttcaca gaatccattt ggtggacaat caatcgatat tagcgatgat
     8341 gatctaccgt tttaagtagc attttctatt ggttgcattt gctacggttt atgttataat
     8401 ttagtcaaca aaaagaattt tcaatctata accaaaaacc actagctggc gggctagtgg
     8461 ttttctttta cgtttctatt ataagaatta acgagtaggc ttactgtctt tcttggcaaa
     8521 tttacaatca agccatttgc agatatagtg cgcggctact tctgccatga ttgcaaaaac
     8581 aaaatcaaaa agaattttca aacctataac ctcctcccct tgccagatta ggccggggta
     8641 gcagacagca agactattat agcataattg aaatatccaa atgattggat ttttgctata
     8701 attttagcga ggtgattgtg atgaacaaat atgttggttt gcttgataaa atccgagtaa
     8761 taaaaacgca accgttattg gttcgcttta ctttacaaac gattcatgaa tcgattaatt
     8821 gtgtagttgc agatattgaa attatcgata aattgctaat tatggatgat ggaaaataca
     8881 atattgccgt cacaggtcac ttcaataaac gaaatcagct ggttattgct agcatgtatg
     8941 ttagaaatcc cgatcatttt acacgatcga tgggcatata aataaaagaa gagttgtagt
     9001 cctaaatgag gattgcagct ctttttgttt tacatagaaa cgggaacagg aaaaggcctg
     9061 tttaggaagg cacaagcgcc ttctcaatta aaaaaccttt ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgctg cacgttcact aagatatggt gtcttgcaaa
     9181 gcaagacaaa ataggaaaag cttcctctca ccaaaaggtt cgttcctgtt cgctatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggagaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt atggcgatta
     9601 cattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cacaacacaa attattgaat
     9661 gtaaaagaag tcatttctga aaaagtagca gaagctttac ttattccgcg gtactggacg
     9721 atagaaaccc ctttagtaga ggacgcaccg actatgctat ttgaagacct agtgaagatt
     9781 gcaggatatg aactgcatta tcaagaaaac ttggaaactt atgaaaacga atattggtta
     9841 accaaattag agaactaaaa aggagaaaaa atatggctca gaattactat gacgaatttg
     9901 tcaaattacc tttggataaa atggcacaaa aaatggagga tatgacgttc ctataccatg
     9961 aaacacgtgt acccaaaaaa cattacaagg aaaaattgtc agtcgcagtg gaagaaatga
    10021 ttgaatcagg tgtcgaaatg aatctcattg cgacgtacta tcgaacattg gaagaactga
    10081 aaaaacaaaa tggaaaatgg tttttccaag ccttactatg cttggaagca ggcgtcaaac
    10141 caagcacaat caaaccttct gaataccaag ctttagaact aacgtatgga aaatttatcg
    10201 aaacgaaaaa agccaagact gtttcaagtg aatggttgga ctactttgaa aatgtcaaca
    10261 agtatggcgc atgttacatc atgaaaaagg aggacaacga aaatgagtaa tgtggtttat
    10321 caactaacag tggaagatgt ttctcacttt ttaacaaaca aagaacattt gaatgaagta
    10381 gtcagacgga ttcaaaaaga ctttagttgt atggaagaaa tgaagtactt tattcaaaga
    10441 gtggaagaac agttgtatat ggaaagcgaa acgagtcaaa cgaaggtcac agtcagccat
    10501 aatcatttag acgtgtataa acgtcgtcct gaaacggtaa aaaaaggaac agagcttcta
    10561 cgactagaaa cagaaaaata catcatgaat gtgtacctag aaaggagtga gctggtcgaa
    10621 aactttgtca gctacacgat ttgtaggaaa cactattact cagaatcaga atattattca
    10681 atttttgaga gcatggaatt aatggaagaa gaaatggaag agctaaacag caaaaatgcg
    10741 acggtagacg attattacct tgtatttact agatttctga cgtgtgggac ggaatctatc
    10801 gtgttaatgg gaatggatta tgaactcgct gtacccgaag catttttgag ggaatatgta
    10861 gaagaagtag ataacccagg cgacgactgg tacacgactt taactgattt tttagatacc
    10921 tacacttacg acgatacaga agaaatccaa aatgagcttg actgtaaacg aatgccatat
    10981 caacgatttg aaaggaaaaa aggtcaataa ccatttatac cgaaaagtga gaatgtgtga
    11041 aataagaaca aaaaaccttg aaattaaggg aatggttctt atttcgcacc aatcgctcca
    11101 accgcccccg ccgctcaggt ggtgcgaaat aagcgggcaa cgaccgataa cctaagagaa
    11161 agaaggaaat ccatatgaat aaaatcattc ctctgttgtt cgtactgttt gttggcgaga
    11221 tacttatgcg tcatgctgca gctgtacatt taaacttcgt agtattctta ggaatactgg
    11281 tattttgttt gatcttttgg cgatttgtat tagcccttgt gagtctacta ttcaagatga
    11341 ttgcagccat atttttcata gggttatttc gatgaaagga gagagtacta atgccaattg
    11401 caataggaaa taaacgttta cccgtgacgt tggatgaaaa gagacaaaaa gaattgcagg
    11461 aactcaaaca gaagtacggc aaaagtgaat ccaggattat gtgtattgcg ttagatttat
    11521 tgattgcaca agaaaaagca gggtttgatg taccagcact caaaaagtga cgtcactttt
    11581 catttgaaga aacaaaagtg atagcacttt acgcacgtgt cgatacgtgt tatgattatt
    11641 ttgtaaggag gtatagtgca caatgccact tacgggaaaa gaaatgctta agttattgaa
    11701 aaaaaatggc tgggttgagc gaaggcaaga gggatctcat catcatcttt ataaggatgg
    11761 tgttagaatc actgttcctg ttcatgccaa tcaagatctt ggccgaggac ttgagcaaaa
    11821 aattttaaag gatgcgggat tgaaataatc tcgcattcga ttaaagaaag gattgactga
    11881 aatgttaagt gagcctttag caaaaaccta tcctgctatt tttagcccag aagaaggtgg
    11941 tgggtacttt attgaatttc ctgatgttca aggtgcttac acaggaatta acgaagacga
    12001 tatatcttat ggaattgcta tggcacaaga ggtgttaggt atggttttag cagattatat
    12061 tgagcatgaa gatctacttc cagaaccaac accaatcaat aagatttctg ttgaagatga
    12121 ttcttttact actttaattc gtgtagatgt tgccaaatat ttgaaagaca cagaacttgt
    12181 caaaaaaacc ttaacaattc ctcaatgggc ggataagcta ggcaaaaggg ctggcataaa
    12241 tttttcagtc cttctaacag aatcaattgc agataaagca gataacattc ttcgttctgg
    12301 aagaaataat tagaactcaa aagagtcaga aacttaaaaa tctttggctt ctttttttac
    12361 tacaaagatg gcttctttaa attatttgcc tgattgattt aaaaaaattg cgcaaagact
    12421 acgagctaat taagttgctc gtggtctttc tttatgaaaa ctttttagat ctagataaaa
    12481 acattgagac actttgaaaa atttttttaa tagtaatggg cgcttctatg tcaagctgat
    12541 tcttctttcg gtaaattaat tttacttaga atatcactat cttgataaaa aatggtgtat
    12601 tcacaaattc tggcataaaa aatacctact ttctagttaa ggttcctgaa taagtcgcaa
    12661 tccaattatt tccagctgat ttataacttt ttaaatataa ttttccataa taccaataac
    12721 cattactttt ttctgtccaa tttcgttatt gagaagatct agaaggccag ccaactttat
    12781 caaaaatcat cattcctgtc actcgtatcg ttttagaagc tgctcgagta agtaatggag
    12841 aaactgttaa ataattttaa gtaacagtta agtcgttagt tgggttatca atggctattc
    12901 cgtccttatc tgaacctcga aacccaatca tagaaaaagt tttttgaaca agttttaaca
    12961 gataaatcaa gttatatact agaaaattcg taaaatatat ttttaatgtc ataatcgttt
    13021 gatttttctg gattgacatt tatttataaa aaatagtgcc attaaaaaag aaaagtgaca
    13081 caccaataaa agtcatatcc tgtgacatta tatggcatta tccaaataga ataaccggtt
    13141 gacatgtaag cggattcctt ttataatttt aggagtataa gtccttttct aaaaatatta
    13201 accggttatc atgaaagggg atacaaatat atcgttggag gataaaaata tgtcaaaggt
    13261 taacgtattt aaaaatcaat cctatttaca aagttcagct acattattac tattttttgc
    13321 ttcttggggt gtttggtggt cattttttca actttggcta acatctgaat caaatggttt
    13381 agggttatct ggcagtgctg taggaacagt attctcggca aattcgttag ttaccttaat
    13441 tttgatgttt atttatggaa cattacaaga taaattgtat attaaacgaa atttattaat
    13501 ttttgcttct gtattagcga cacttgttgg accatttttt atatggatat acgggccatt
    13561 gctagataac aattttaatt taggcattat tatgggagca ctatttttgt cagctggata
    13621 tttagcttct gtaggagttt ttgaagctgt gtcagaaagg tttagtcgtt tatttggctt
    13681 tgaatatgga caagcaaggg cgtggggatc atttggttat gccttggtag cgcttttggc
    13741 aggattttta tttgtaaaaa atcctcattt aaacttttgg gcgggatctt tctttggttc
    13801 tttactattg ttaaatttat tattttggaa ccctaaagtt gaacgggaag caaatcaaaa
    13861 ttttaatcaa gaacaagctg aatcaaatag tattccttct ttaaaagaaa tgtttgatct
    13921 aatgaaactg cctcaattat ggacgataat catctttatt gtttttacat ggacatttta
    13981 tacggtattc gatcaacaaa tgtttccggg attttatact ggtttgtttt caacatcagc
    14041 taatggtgaa aaaatatatg ggacattgaa tgctattcaa gtattttgtg aagcgttaat
    14101 gatgggaatt gttccaatca ttatgagaaa attaggggtt cgaaatactt tgttattagg
    14161 tgtaaccatt atgtgtgtac gaattggatt gtgcgggttt gcctcgacac cattatctgt
    14221 ttcatgcata aaaatgttgc atgctttaga agtaccatta tttacattac caatgtttcg
    14281 ctattttaca cttcattttg atacaaagct atcagcaacc ctctatatga taggatttca
    14341 gatagctgct caaattgggc aagtgatttt atcaacacca ttgggaata
//
LOCUS       DAZKPE010000071        14014 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000071 DAZKPE010000000
VERSION     DAZKPE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.071"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            273..2438
                     /gene="acm"
                     /locus_tag="ACG930_002314"
     CDS             273..2438
                     /gene="acm"
                     /locus_tag="ACG930_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFQ0519465.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2710..3195)
                     /locus_tag="ACG930_002315"
     CDS             complement(2710..3195)
                     /locus_tag="ACG930_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFQ0519466.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3285..3630
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3675..4316
                     /locus_tag="ACG930_002316"
     CDS             3675..4316
                     /locus_tag="ACG930_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0519467.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4335..4970
                     /locus_tag="ACG930_002317"
     CDS             4335..4970
                     /locus_tag="ACG930_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519468.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4988..5803
                     /locus_tag="ACG930_002318"
     CDS             4988..5803
                     /locus_tag="ACG930_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0519469.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6122..7558
                     /locus_tag="ACG930_002319"
     CDS             6122..7558
                     /locus_tag="ACG930_002319"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0519470.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7747..10194
                     /locus_tag="ACG930_002320"
     CDS             7747..10194
                     /locus_tag="ACG930_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFQ0519471.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10424..11491
                     /gene="rlmN"
                     /locus_tag="ACG930_002321"
     CDS             10424..11491
                     /gene="rlmN"
                     /locus_tag="ACG930_002321"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFQ0519472.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            11481..11687
                     /locus_tag="ACG930_002322"
     CDS             11481..11687
                     /locus_tag="ACG930_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519473.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(11684..12787)
                     /locus_tag="ACG930_002323"
     CDS             complement(11684..12787)
                     /locus_tag="ACG930_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0519474.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13340..13888
                     /gene="aac(6')"
                     /locus_tag="ACG930_002324"
     CDS             13340..13888
                     /gene="aac(6')"
                     /locus_tag="ACG930_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFQ0519475.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4820 a         2308 c         2959 g         3927 t
ORIGIN      
        1 gcatttttgt aagttaaaaa ttggaaatat agattgaaaa aatgaaagca ataagtaaaa
       61 taaaatgaat atatgcgaaa aaataattta cattaggaaa aaccttgtaa aaacagtttt
      121 ttggcatatt tattttttat aaatatttgt aaaataacta tcaatttttt agttaaaaga
      181 ttggaaatga gtgggggagg aattgaagaa aggatttttg agagatgata tagtaggttt
      241 tatttttagt taaaataggg gagatagaaa aaatgaaaaa gtgtagaaat attattttat
      301 caatgttatt tattattact aatataacat cactgattcc tgttcatgtc tatgcggatg
      361 caggcagaga tatcagcagt aatgtcactt cgttgaccgt ggacccaacg aatattacag
      421 atggaggaaa cataaaagta aaattctcgt ttgacgaaaa aaaacaaaat atccaaccag
      481 gtgattatct ttggatcaat tggccaagtg aaggaaatat tcgcggtgaa ggattccaaa
      541 aagaaatccc attaatgatt gaaaataaaa atgttggaac tttaacggtc agaaaagatt
      601 ctgcgcaggt tgtgtttaat gaaaatatta aaaacctaga ctcagtagaa ggttgggggc
      661 aatttgagat acaggccaga aacgtaaccg ataccggtga agaaaatacg ggaccattca
      721 ccgtgacgag cggtgataaa acagctactg taaatgtgac aaagccagct tctggttctt
      781 cttctagcgt tttttattat aaaacaggag acatgctacc tgaagatact aagcacattc
      841 gatggttttt gaatattaac aataacggca cttatgttga acaaccagtt aaaatcagtg
      901 atgaaatcca aagtggacaa agattagatc caagtacgtt tgaaattaat caaatacact
      961 taggtgaaca gaaggtttat agaggagaag agggaatcca acaattttta caagatttcc
     1021 ccagcgctac atttaatttt tcagtaactg ataattacat tgaaataact ataccaaaaa
     1081 actttgtcaa tcttaggaaa ataatggtga gttataagac gatcatagaa aacccagaac
     1141 aaataaattt tgagaatcat tcggaagctt ggtttaaaga atttaataaa cctgctgttg
     1201 atggagaaag tttcaatcat acagttaaaa atatttcagc ttctggtgga gtcaacggta
     1261 cagttagagg cgaattgaag attttcaaat atatcaatga cacagagatt ggtatcccaa
     1321 atgtgacttt cgaattaaga cgagcagatg aacagcctat tcaaggacag tctagtatcc
     1381 tgttgacttc gaatgaacag ggagaagcta gtatcaaagg cctgcaagta ggagactatg
     1441 ttgtaaaaga aaaagaagca cccaattgga ttgattttga tccactaagt tcaaatgaac
     1501 tcaaattctc cataaacgaa aatgatacag agggagtcag tttacctatt tataacaaga
     1561 aaaaggttac gaacatcaca gcaactaaaa tttggaacgg tggaaccact ccaagaccga
     1621 gtatttattt taaattattc agagcaagta caaacaattg ggaaccagtt cctgatgcag
     1681 aaacaaaacg attagacaat ggaataactt cagtgacttg ggaagatatc caacagtatg
     1741 atgatagtgg aaacgaatat acgtttaaag tgcaagaagt agatcaaaac ggaaatgatt
     1801 atgtcccttc aggttatcaa aaaattgaaa acgggctagt cgttacaaat gagaataaag
     1861 aagtcatttc agtctcagga caaaaaacat gggaagacaa tgagaaccaa gacggcaaac
     1921 gaccgacgac gatcacagta aatctattag ccgacggtca accgatccaa cacaaagaag
     1981 taagtgaaaa agatgattgg cgctatcgtt tcacaaatct gccaaaatac agagacgggc
     2041 aagaaatcat ctatactgta acggaagaca acgtgcccga atacagtacg acgattgacg
     2101 ggtataacat caaaaacagt tatacaccgg aaaaaacaaa tatatctata ccaggtagcc
     2161 atataacacc gtggaaaaat tttccagaga agacagagag agagaaaatt agaaatctat
     2221 tctctcaaaa attgcaaata tttgctcata caggagaatc cagcgaacaa agaagcaatt
     2281 atattagtaa gagagctgta cctaaacaga taacaaataa atcaaaaagc attcttccta
     2341 aaacaagtag taaaaaatct agttttgctg taatcattgg tttattgata gtaactatct
     2401 gtgctgggat attcttacaa aaatataaaa aagtttagtt agaatataat attttttgtt
     2461 aaatatgact gaaatcaaaa gaataaaatt ccgatttata atcgaaaaaa gaagcatttt
     2521 tatatatgct tcttttttcg tagaatcaat aaatatggat ttggctaact atggaagaat
     2581 actcgtatta gttttcagcg ttcatactag ttgttacatt gtttgattgg ccaaaagaat
     2641 ttctgatata ttttgtgcta aataaagaaa aagacgcttg aattgggaaa taagaaaact
     2701 actctatcat tacaaatttt cataaactgg cagatgttct aagtaaacaa gtatcttttc
     2761 aaagtcggaa aaatccataa tcaacgtagt ggtattgata tttggatgaa agcctacggt
     2821 atcttgacga tcaatagcag catcgatcac gacttggatt tttttctctt tgtcgtgcat
     2881 caatgctaat ggagtcactg tacctgctgg aacgcctagg aggtcaggaa gctgttcttc
     2941 agaaacaaaa gataagcgct tttcttttaa ttgttcagct agttgtttta aatcggcgtg
     3001 cttttcatca ggcaagatga caagatagat ttgttttcct tttcttgatt tcaataatag
     3061 attttttact tgcggaccag gtagggaaaa agggacattt ttgactgacg taatcgcagg
     3121 atgatcgact ttttgaaaag agatacccag tttttttagt agttcataag cttcttgttc
     3181 ggttgcacga ctcatcgcgc atcaccctcc tttttttatt agtgtatcat aaaaaagagt
     3241 tgacaaatga aaaataatca tgtaaattac acgtaaagtt aaaacaaatg acatcgaaaa
     3301 gaagagtagc cgttaggtgt ttttagagag tctctggttg gtggaaagag gcagcagtta
     3361 accgtgaaac acatcttgga gtcgattttc tgaagcgtat agtaggaaaa tccggggagc
     3421 ccgttacagc tgcggtcgtt gctagatgac cagataaggc tggcttttcc gtgaggagtc
     3481 ggtaaaaaaa ggtggaacca cgtgattaac gtcctttgat cttcggatca aaggactttt
     3541 tgttttcatc tgaacggcaa cgactgtgtg aggttttttc tgcaaggaaa aaataaacag
     3601 aggtggaacc acgtataata cgtcctcttg gcatttgcca agaggatttt tttattttaa
     3661 aggaggaaaa gaagatggag tatttgattg aagttatgcc gcaattatta gtaggagcac
     3721 tcacaacatt gaaattattt ttatttacct tgattggctc attaccatta gggattgttt
     3781 tagcattagg attgtctttg cattttaagc cgctacgcta cttgcttcaa acatatgtat
     3841 gggttatgcg gggaacaccg ctgttgttgc aactgatttt tattttttat gggttgccga
     3901 cgattgggat cgtttttgat cgtttcgaag cagcactcat tgcctttatc ttaaactatg
     3961 cagcttattt tgcagagatc tttcgtggag ggatacaatc gattcctcaa ggtcaatatg
     4021 aagcagcgca agttttgcaa ttaagtccct ttcaaacggt gacgaaaatc gtcatcccac
     4081 aagtgacaaa gattgtttta ccttctgtag ggaatgaagt tatcaacttg gtcaaagatt
     4141 cttccttgat ctatatatta ggtttaggtg acgtaatgcg tgctgggaaa atcgcgatgg
     4201 aacgcgacgc gactttactg cctttgctag gcgtggcaat catctatctt acattgactg
     4261 gtattctaac aatcgtaatg aaacaagttg aaggaaaatt aaattattac cgctaactga
     4321 taggaggaag aaatatgatt gaattgaaga aagtgaacaa agcatttggt gaaaaaaaaa
     4381 taatcaaaga tttgaatcta atcattccag atgggaaaac attagctatc gtaggtcctt
     4441 ccggtggcgg taaaaccacg cttttacgta tcttggctgg cttagaaagt tctgacagcg
     4501 gagaatttta tttagacggt gtaccgttca acccattcga gcttaaaatg aaagaacaag
     4561 ttgtaggagt cgtattccaa gacttccagc tatttccaca tctgaatatt tttgaaaaca
     4621 ttaccttagc accaaaaatg gtattgaaac agacaaaaga agaatacacc aaaaaagcag
     4681 aagaattagc ggcttcatta gggattagtg atttattgaa tatctatcct tatcagcttt
     4741 ctggcggaca aaaacagcgg gtagcgattg ccagagcatt ggctatgaat ccacgggtat
     4801 tggcttatga tgaaccaaca agtgctttag atcctgaatt acgccagcaa gtcgagcgtt
     4861 tgatcctatc attgaaagaa gatggggtaa cccaaattat tgtcacccat gatttagtat
     4921 ttgcagaaaa tgtcggtgat caattactaa aagtttcccc aattcattaa gaaaggagaa
     4981 gatagagatg aaaaaaacca gttttctatt cgctttgatc gcaggtcttc ttctttttgc
     5041 aggctgttcg aacaaaaaaa cttcagcaga taattgggcg actatcaacg aagagaaaaa
     5101 aatcgttata ggtttagacg atacatttgt tcctatggga tttagagata aagacgggaa
     5161 gctcacagga tttgatattg atttagccaa agcagtcttt gaacaatatg ggattacggt
     5221 agactttcag cccattgact ggtcaatgaa ggaatttgaa ctgaacaatg gaacgatcga
     5281 tttgatatgg aacggctatt ccaaaacgcc ggcaagagaa aagaaagtgc aatttacaaa
     5341 accttatatg gaaaacgatc aagtgctgat cacacctaaa gaatcaggaa tcacaaactt
     5401 tggacaaatg aataataaga gattaggtgc gcaaaatggg tcatctggtt atgatgtatt
     5461 tacgaaacaa ccagaagtat taaaagagat agtcaaaaac caagatgctg ttttgtatga
     5521 tagttttaat gaagcattga tcgatctgaa aagcagacgg gtcgatggtc tgctgatgga
     5581 taaagtatac gcagactatt atttgaaaca aagaaacgaa ctagaagact tcaacataac
     5641 aaaaggttct tatgagagtg aggattttgc agttggtgca cgcaagtcag atagtacatt
     5701 agtgaaaaaa atcaatgaag ccctagatca actagagaaa acaggtgaat tccaaaaaat
     5761 atccgataaa tggtttggcg aagatgttac gccgagaaat taacaaatag gggactgtga
     5821 caaaagacgt gtcacagtcc ctttttccga ataaacagtg ttctcctgcc aactccttgt
     5881 gactcggagc tgaatggcag gctcacaacc tcttggtaaa cggtgttcaa aagccagttt
     5941 ttcggtatta agccaaattt atgcaaaaat gtagaaagcc attttcacaa aatttttctt
     6001 actactcgaa actaagcgac tttttcacaa cctcctttac ataattttat tttgttgtgg
     6061 aaggggtttc gtgttattct aaaagaggaa cgattgaagg ttataggaaa ggaagagatg
     6121 aatggaacac aaagaactta cctcatttcc aaaagatttt ctgtggggct ctgcttctgc
     6181 agcgtatcaa gtagaaggag cttggcaaga agatgggaaa ggagaatcag tctgggatcg
     6241 atttgtacgg atacctggaa agacatttaa aggaacgaac ggtgatttgg cagtagacca
     6301 ctatcatcgt tataaagaag atattgcttt aatgaaagaa caaggtctga aagcttaccg
     6361 cttctctgta gcttggacac ggatttttcc taatggacga ggagaagtca atcaagctgg
     6421 gctcgctttt tatgagagat tgatcgacga attgattgaa aacgatattg aacctatgtt
     6481 gactttatat cattgggatc ttccacaagc attgcaagat gaatataatg gttgggaatc
     6541 acgtcagatc attgaagatt tcactcatta tgcagaaaca ttatttgagg cattccgcgg
     6601 gaaagtccat tactggatta gtttgaatga acaaaatatc ttcacttcat taggttattt
     6661 gttagcagca catccgccag gtgtgacaga cccgaaacga atgtatgaag ttaaccatat
     6721 tgctaattta gcaaatgcat ctgtcatcaa taaatttcac gagttagaaa tgcctggaaa
     6781 aatcggacca agctttgcgt atacgccaaa ttatccaatt gacagtaatc ctgaaaatgt
     6841 tctggctgct gaaaatgcag aagacctgat ggccaattat tggatggatg tctatatgtg
     6901 gggaaaatat ccgattgctg ccatgaggtt cttagaagaa aaaggatggg caccaacgat
     6961 tgaagctggc gatgcagaat tgctagaatc tgctaaacca gattttcttg ggatcaatta
     7021 ctatcaaacg gcgacgaatg cattcaatcc attaaacgga gttggtgctg gaaaaatgaa
     7081 tacgacagga aaaaaaggtt catcagaaga aactggagtt cctggaatgt ataaaaaagt
     7141 tgagaatcca tttgtcgaac gaacaaattg ggactgggag attgacccag aaggattaag
     7201 gatcggactg cgtcgtatca caagccgtta ccgcatgccg gtactgatta cggaaaatgg
     7261 cttaggagag tatgacaagt tgacagaaga taaacaaatc catgacgact atcgaatcaa
     7321 ttacttacaa agccacgtca aagccatcaa agaagcaatt tcggatggag cagaagtcct
     7381 aggctattgc acctggtctt atacagattt gcttagctgg ctgaacggtt atcaaaagcg
     7441 atatggattt gtatatgttg atcaagacga aacacaagaa ggatctttgg aacgatataa
     7501 gaaagacagt tattactggt accaaaaact gattgaagaa aatggagaga acctttagtt
     7561 cacatactta aaacaagaag gtacggctgg atatggccgt gccttttctt gataaaatca
     7621 tttagaaatt aagaaaaact gtaaaataag ctgaaaaatg aaagaaagcg tcagttcttt
     7681 caaacaaaac tttagttccc ttactttttt ttgtataatg aaacttgatg aaatgaggga
     7741 taataaatgg cacaaaagaa acggcctact aaaaaaagga aaaagacgaa aaaaacgaaa
     7801 aagcaaaaac agcagcagga acaaatgctg acgattggtg ttgggtttgc cttgatttta
     7861 tttgctgtct tcggcttttt aaaattaggt tttttaggaa tattgattgc aaacggcttt
     7921 cggatcattg caggaaatac ttaccaaatc ctctgtcttt tattagccgt attaggattt
     7981 tggattgtca ttaagaatac agagttttca attggtaaaa accgacgctg gtttggcggc
     8041 atactctttt atttcggtat cttattattg ttacatgccc atttatttgg caaactccat
     8101 actggggaac caaatatcat ggggacgaca tgggatttgt tagccagtga tataaaacaa
     8161 agtcaagtag acaataacgt tggtggtggg atgattggag caatccttta tcattttact
     8221 tacttcttga ttgcacagcc tggaagttat ttagcagcag tgctattact ggcaggagga
     8281 gcattcctgt tcagtaatct ggaaggctat cagctgttaa atggtatcca atcaattgga
     8341 gaacgagtac aggaattatt ggaaggtgat cctgccaagc aagctcgaaa gcaagcggca
     8401 aaggaagaga gaatgaaaca gcgcgcagaa gcgaaagaag caaggcgctt agctgcaaaa
     8461 gaagctgcag aaaaagaagc tgcagaatat gagaagaaaa aagcggtgag ccagcaaagg
     8521 gaaaatactg ctgatgaatg gcaggaacca gaaaatacag agccggagca gctaagtttt
     8581 gttccaatcg acagttttca agaaaatatc catcctgcga atctagagaa accagtacca
     8641 gatacaccaa aacagaccaa tacagcagaa ggtttttcag atgagttgcc agaggatgac
     8701 ggtacctcat tagaatttga gattgaagca gaacaggaaa atcaagacta tgaattaccg
     8761 acagttgatt tgcttgattc tataccaact gtggatcaaa gtgatgagta taaaaaaatt
     8821 gaaaaaaata tcggcgtatt agaacaaact ttccaaagtt tcggtgtcga tgccaaggtc
     8881 gtcaaagcca gcttaggacc atccgtcaca aaattcgaag tccagccggc tgtaggggta
     8941 aaagtaagta aaattgtgaa cttaacagat gatatcgcgc ttgctttagc ggcgaaagat
     9001 gtccggatgg aagcaccgat tccaggtaaa tcactgattg gtattgaagt accaaatgga
     9061 aagatcagta tggtttcctt tagagaaatc atcgaagcac aaccaaacca cccagataaa
     9121 ttactagaag tacctttagg acgtgatgtt tctggacggg tacaaacggc tgatctttcg
     9181 aagatgcctc acttactcgt ggctggttcg actggtagtg ggaagtcagt agcaattaat
     9241 gggattatca caagtatatt aatgcgtgct aagccccatg aagtaaaact gatgatgatc
     9301 gatccgaaaa tggttgaatt gaatatgtac aacggcatac ctcatctgtt gacgccggtc
     9361 gtgacgaacc ctagaaaagc agcgcaagcc ttacaaaaag tagtacaaga aatggaagaa
     9421 cgatatgaaa aattcgcggc aaccggagta agaaatattt ctggttacaa tgaatttgtt
     9481 caacagaaaa acttggaaaa cggaacgaaa catccaacct taccattcat cgtagtgatc
     9541 gtagatgaat tagctgattt gatgatggta gccagcaatg aagttgaaga tgcgattatt
     9601 cgtttagcgc aaatggctcg ggcagcgggg attcatatga tcctagctac tcaacgtcca
     9661 agtgtggatg ttatcacagg aatcatcaaa gcaaatgtac cttccagaat ggcatttgcg
     9721 gtatcaagcg gtacagattc tcggacgatc attgattcta atggggcaga aaagctctta
     9781 gggcgaggag atatgctatt cttgccaatg ggtgagaata aaccgatccg tgtgcaagga
     9841 gcattcattt ctgaccacga agtagaacgg gtcgttcaat ttgttacaga tcagcaagaa
     9901 gctcattatg aagagaaaat gatgccgaca gatgaagttg aaacgacagg tgctccagaa
     9961 cagccacaag atgagctgtt tgaagaagca aaagcacttg tcgttgaaat gcaaacggca
    10021 agtatttccc ttctccaaag aagatttcgg atcggttaca accgagcagc acgtttagta
    10081 gatgaactgg aagctcatgg agttgttggc ccgtcagaag gaagcaagcc tcggaaagta
    10141 ttcattgagc aggaagaaac atcagaaacg ttgccggacg ataatgacat gtaaaacttg
    10201 tgtgatgaag ggttgaaaaa cgaataacca ataaaaagac aaggcatgat gataccaaaa
    10261 gaaaaaatgg tttttttcca tcttttctaa tacggtatga tgtcttgtct ttttagtttt
    10321 tgtgagatta aagttctatt cgatttattt gtgaagtatt gcattaagga aatgaatcat
    10381 gtatagtatg tagcgaaact ttgagaaaaa gagggaaaat actttggaaa aacagtccat
    10441 ttatggcttg acgaatgaag aattaatcaa ttggtttata gaaaacggcg agaaaaaatt
    10501 ccgagctgcc caagtttggg aatggttgta tcaaaaacgt gtaagtaatt tcacagaaat
    10561 gacgaatcta tcgaaacaat tgatcgaaaa attatcggag cattttatca tcaatcctct
    10621 aaaacagatg gtcgtccaag aagcttcgga tggtacagta aaatatttgt ttgaactccc
    10681 tgataaaaac atgattgaga ctgtactgat gagacaagaa tatggcttgt cagtttgtgt
    10741 gacgacacaa gtaggatgta atatcggctg tacgttttgt gcaagcgggc tgctcaaaaa
    10801 gaaccgtgat ctgactgctg gagaaattgt tgcacagatc atgatggtcc aacattattt
    10861 tgatgagcgc aatcttggcg aacgcgtttc acatgtcgtt gtaatgggga tcggtgagcc
    10921 atttgataat tacgacaatg taatggactt tttgcatatc atcaatgatg ccaaaggatt
    10981 ggcaattggt gctcggcaca ttacagtttc cactagtgga ttagcacaca aaatcaagga
    11041 attcgctaat aacggcttgc aagtcaatct ggctatttcc ttgcacgcgc cgaataatga
    11101 ggtgcgaaca tcgatcatgc ggatcaaccg aagtttccca attgagaaat tgatggaagc
    11161 tgtggatgag tatttagaga aaacaaaccg tcgaatcacg tttgaatata tcatgttgaa
    11221 tcaagtaaat gatagaccag agcatgcgca acaattagca gatctattaa aagataagaa
    11281 aaaattagca tatgtcaact tgattccata taatccagtc agtgaacatg atcaatattc
    11341 tcgcagtcca aaagctgatg tattgagatt ttatgatgta ttgaagaaaa acggcgtaaa
    11401 ctgtgtgata cgtaaagaac atggtacaga tattgatgca gcttgcggac aattgcgaag
    11461 caagcaaatg aaaaaaacag ttgccaaata atcgtatcct actcgttttt tcaattacca
    11521 taaaaggagc agttttctta attaaggaac tgttcaactt aaataagaga aaagattcta
    11581 tagcgaaagc tataaagctt tttttgacaa gaaaaaccct catcaagcaa agaaatgtcc
    11641 tcaatttgat gacagcctgc ttgatggggg ttttagcaat tatttaactg attttcttat
    11701 atccttgctg gctttcttgt gtagcatgat aagtttctac gtcaagaatg gcctgtttaa
    11761 atttttctcg ggtgatttca taaggcacat gtttaatatc atttgttgcc atggctttat
    11821 ctaagattgc ttctaaatcg gtcgtgacat tgagattcat gtcggttaac gatactggaa
    11881 gttggttctt tttcataaac acatagattt tatcaaacaa atcgaactgc tgatccatca
    11941 tcaataaggt cagtacacca taactgacag atgctccgtg aaggtatccc tccatttttt
    12001 ctagaacagt cgtaccgtaa tagaatgagt gtgccatagc agaattatag ttattgttaa
    12061 ctaaaacaga aaccaatccg gtagtaacaa tgatatccga aacgacttgt tcaattgcat
    12121 atgagggacg atcgtcggca ctatctttca atgcttgcgt accataagtc aagagacgat
    12181 caatgcacat ttttccgatt tggattccta atctatccgt gtagcctaga tcatcgccac
    12241 gagcagaaaa agtagattcg acttctttgg ataaagcatc gccaatacct gcccataagt
    12301 atttatcagg tgcttcggca ataattgctg tatcaatgaa ggtgtgtaca ggtggttttg
    12361 aaggaaagaa gagtccgtcc attacgcctt cttcgttata gatgacacat accgcagtga
    12421 cgggcgaaca gttcgaacca atagtgggaa aggtgaagac tggtttagct agtttttcac
    12481 caatgacttt tacagtatcg caagcacggc caccaccgac tgcaaacagg acgtctgctt
    12541 tttggacact ttcatgctgg atcaactgtt caatatttcc ataagttgaa ttacccccgt
    12601 accagagact ggcgacaacc tctatttcct gtgtcaaagc tacttttatt ttgttttctg
    12661 cctttgaaag tgcagtcttc cctccaatca gcactacttt tgtcccatat tctttgacga
    12721 ttccatttgc tttttcatac gcatctgttc caatggtata atttggtaag aaaacacttt
    12781 gactcatatt catttccttc tttcttcgtt gaaacgggtt aaaattttaa agagtgatcg
    12841 atctgactgc ggctgtagat ggagtagagg tgaacctaag acaggataag tgatgaataa
    12901 ggtggcatga acaccttgaa atcatcaata agtatcctaa aaacgaacaa gtacaaaaac
    12961 attgaaaacg acaataatga atttttgttc ctcttagtat ttctaccgat tccctttgct
    13021 tttttgtaat tatctaaaaa ttctaaaaat taagattatt atatgaaaac aggttttatt
    13081 tgtcaattca taattggttt tttttaaagc aaaagataat ctatatcatg atgaacaaac
    13141 agagtttttt cctccaattg atggctttcc tgatctttcc tattttgaat aaagtgtttc
    13201 tgtataattt ttttatttta taagtaagat aaataatgaa agaatagaga tactgattgg
    13261 tagctaaaga tttttgagcg agaacatttc gttttttcaa aaggactgtt agaataagca
    13321 agaacaaggg ggaagacgta tgataatcag tgaatttgac cgtaataatc cagtattgaa
    13381 agatcagctt tctgatttac tgagactgac ttggccggaa gaatatggag acagctcggc
    13441 agaagaagta gaagaaatga tgaatccaga acgaatcgcg gtagcagcgg tagaccaaga
    13501 tgagttagta ggatttattg gtgcaatccc tcaatacggt atcacaggtt gggaattgca
    13561 tccattagtt gtagaaagct cccgacgaaa gaaccaaata ggtactcgat tagtcaatta
    13621 cttagaaaaa gaagtagctt ccagaggagg aatcacgatt tatttaggta cggatgattt
    13681 agaccatgga acaacgttaa gtcaaacgga cctgtatgag catacatttg ataaagtggc
    13741 ttccatccag aaccttcgtg aacatccgta tgaattctat gaaaaattag gttataaaat
    13801 cgtaggtgtc ttaccaaatg caaatggctg ggacaaaccg gatatttgga tggcaaaaac
    13861 gattattcct cgaccaaatt ctcaataata aaaagaggtt gtgacagaag taatcagctt
    13921 caagaaataa gaaggaattt acgaaaatta cttcttgaat ttttgtgaaa ttccaactta
    13981 tttccgaaga agctactttt ggaacaccgt gtac
//
LOCUS       DAZKPE010000072        13750 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000072 DAZKPE010000000
VERSION     DAZKPE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.072"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            153..1580
                     /locus_tag="ACG930_002325"
     CDS             153..1580
                     /locus_tag="ACG930_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519476.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1672..2037)
                     /locus_tag="ACG930_002326"
     CDS             complement(1672..2037)
                     /locus_tag="ACG930_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFQ0519477.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2034..2399)
                     /locus_tag="ACG930_002327"
     CDS             complement(2034..2399)
                     /locus_tag="ACG930_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFQ0519478.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2591..2839)
                     /locus_tag="ACG930_002328"
     CDS             complement(2591..2839)
                     /locus_tag="ACG930_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519479.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2838..2966
                     /locus_tag="ACG930_002329"
     CDS             2838..2966
                     /locus_tag="ACG930_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFQ0519480.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            3023..4717
                     /locus_tag="ACG930_002330"
     CDS             3023..4717
                     /locus_tag="ACG930_002330"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFQ0519481.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4817..5113
                     /locus_tag="ACG930_002331"
     CDS             4817..5113
                     /locus_tag="ACG930_002331"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519482.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            5491..6624
                     /locus_tag="ACG930_002332"
     CDS             5491..6624
                     /locus_tag="ACG930_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFQ0519483.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6655..6975
                     /locus_tag="ACG930_002333"
     CDS             6655..6975
                     /locus_tag="ACG930_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFQ0519484.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(7004..7468)
                     /locus_tag="ACG930_002334"
     CDS             complement(7004..7468)
                     /locus_tag="ACG930_002334"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0519485.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7599..8852)
                     /locus_tag="ACG930_002335"
     CDS             complement(7599..8852)
                     /locus_tag="ACG930_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0519486.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8881..9198)
                     /locus_tag="ACG930_002336"
     CDS             complement(8881..9198)
                     /locus_tag="ACG930_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFQ0519487.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9224..9544)
                     /locus_tag="ACG930_002337"
     CDS             complement(9224..9544)
                     /locus_tag="ACG930_002337"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0519488.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(10008..11423)
                     /locus_tag="ACG930_002338"
     CDS             complement(10008..11423)
                     /locus_tag="ACG930_002338"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFQ0519489.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11440..12756)
                     /locus_tag="ACG930_002339"
     CDS             complement(11440..12756)
                     /locus_tag="ACG930_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0519490.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYTVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12906..13604)
                     /locus_tag="ACG930_002340"
     CDS             complement(12906..13604)
                     /locus_tag="ACG930_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFQ0519491.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4368 a         2789 c         2361 g         4232 t
ORIGIN      
        1 tagaattatc tgttttccaa attttataac ataaaaaacc ttttttaacg gcatttatat
       61 gctttttcag aaattaactg atgatttcaa aaagaaaaca tgtcataata tttcccatat
      121 tgtgcaaaaa aatacaaggc ggaggctcta ctatgattga agaatatatt gagaaaaata
      181 ttttaagaca gctgttttta tgtgggcaat tctatgtaaa taaagaagtc aatctagaaa
      241 agctctccaa tctcctgcat gtttgcaaaa ccactttact caatgatatc aataacataa
      301 aaaaagaatt tgaagaacag atcgcttata cacatcggga aaaggaccgt tacactttat
      361 atttttcaga acatatacct cgatgcaaga tcatgcagca attgtctcaa aattcgttgt
      421 ttttaaaaac ttgtctgctt tatttggaag aagatgaacc tgattatctt caattaactg
      481 aatgtgaatt catctctgtc agcaaagctt attcattaaa aaaacaagta ttagcttatt
      541 ttaatgactg cgggatcgaa atcgaccgct actcccctcg attcactgaa atggaaagac
      601 gtctgctgct tcttaatgtg tcgtatcgtt taggcggttt taattcttgg gagctacctg
      661 aatcgttttt tgaacgtgcc gatcgtttca ttgaatccgt aacggaaaat agtggcagat
      721 tttatgataa agaaaataaa gaaatcttat cgattggttt tgctatcagt ttcctacgcc
      781 agcaagtgtg tgctgtgaca atagattcaa aatttatcga agaaatcaaa aaacgtccta
      841 tttacaatta tgtcgaatca gcatgggaaa acactgattt ccaaacctat tataaaaaag
      901 aagaattcgc ctttattttg acactattca atctttgtaa ttatggtttc cattcttatc
      961 agttgattgc ggaagacttt caacagctac accaagtgtt tattgacaat actcccgaaa
     1021 taaaagaact agttgctacc tttgaatctc acttcaatca agaattattc ggaaaccaac
     1081 cgttcgaacg tgcgctgatt catctgatgc gttcggcttg ggataactat caattattca
     1141 tgccagaaaa attttatctt ttaaatgagg aacagacaaa tttatataaa gaagtccaga
     1201 caattttttc cagctggtcc agccagttac cttatgatct acggttgaat cctaattgca
     1261 tgcgggcttt tgtgatcgaa ttgagcggaa ttctccgtct gacaaaagaa catctgacta
     1321 tctatatcgt cacaaattcg gatgttcatt atctgattta tcgggaagcc ttggaagctg
     1381 taactacttt cgattttcaa gttgcaccaa caatttattc aagtatatct gatataaaga
     1441 agtatgcgca gcagtcctca aaccgggtat tatgtgaacg tacattatat acaccagatg
     1501 cggtccaata tgaaaatatt attcctattt cgatcaatac gatcgatcga gctatcattt
     1561 cagctgtgca aaacaaataa ggggctgtga caaaaatcat gtcacagcct cttatttgtt
     1621 gaagatgccc atttctgtaa caatctcttg atacacgtca ggctcacaac ctcacttatt
     1681 ttggacatct acgggtccga tctctttatt taaaaaataa gaaatgatgg ttcggataac
     1741 taccaacgcc gctagttgga aaatatcctg caaggtaggt ttgataatcg attcgatgat
     1801 cccagctgaa acaagaattt ccaaacttag aagtatatag cctcccaaca tctttttaat
     1861 agcattgttc tcgctgactc ggtcgctttg cacttttgta tggacaaata aatatttcaa
     1921 aaaatccttg attgatagac aaacacccca aaccaataaa cagatagcaa agatatcaag
     1981 tcccagtaca agtttttcga aatatggaag aagaaactgc atcaactctg tcgtcatcct
     2041 acctctcctc ttctttgttt ttctttgtct tctatttcct gattcaagaa ataagaaatg
     2101 actgttcgaa tgataataat aagtgcaagc ttcaaaatat ctgtccaagt cggcttgata
     2161 actgactcga tgatatcagc aacgactagt acttccaagc ttaacaaaat ataacttgct
     2221 agcagttttc ttgtatctgc attacgagta ttacgttctg catagttttt cttgacatga
     2281 gaccaatcaa aaagtttgaa tagaacaaga acgatcccga caattaagat accgatagaa
     2341 caaatattta aaatagcaat gatccattct agaaattcaa ttaaatttga gcgaaacata
     2401 tacgctacct actttctttt aatttgttcc tattctttta ttgtaaaaga aagttacctt
     2461 gttcgtctat ttaaaagttg ttctaatgat aacggttcgc ttaaattttt ctttttcact
     2521 ctcccatttt tctccctcca tccataaatc gtggaagtat ccaaaacaac gtagcaagtt
     2581 aaaataaggc ttagtccgtc atcagctttt caaagaagca ctgtctcggt gctttttttg
     2641 tacccaaatt tctaaaaata gaaccataca cctcctcaaa tcttttcttc ttacctaccc
     2701 tatttttatt tacaggaaaa tcagacactt cttctttttt gtcaaaattt cctttttctt
     2761 ctcgtcctat catttggcat tctaataaaa acgaactatc cttggatata gaaagagaaa
     2821 acaaggaggc gtttttcatg agtaaaaaat taatcaaagt cggcatcggt ttaggtttgc
     2881 ttgcccttgg cgctgcatat ctaggaaaaa agacaggact attcgaagat gacagtcatt
     2941 tatatgatga attcgaatca atctagcatc ctatttagtt gaatcactac ggacatactt
     3001 ggaagacatt ggaggaatca caatgagaaa aagtaaagca ataatgattg gtgccggtat
     3061 tgccaatatg gcagcggctg tttatttgat tcaagaaggc aaatggaaag gggatcagat
     3121 caccttttat tcattggatg atcacggttc aaatgatggt gcaccgaccg acactgtagt
     3181 ggatgaatat tggaataaaa accatccatt agaaaaccaa aaaggctata ttgctcgagg
     3241 cggtcgcatg cttaattacc gtacctatgt agatttgatg gatctgttaa gtcgaatacc
     3301 ttctgttact gagccaggga tgactgctga agaagatacg agagattttg atgcaaaaca
     3361 ccgaaccttt gacaaagcac gtttgatgga aggtggcaaa ggaatcattg atggcggaaa
     3421 actgggattc aataataaag accgtattct tctgactaaa ctgattgcta tgcctgattc
     3481 agaagaagaa aaactagaca atatcactat cgaagaatat ttcaaagatg atccacactt
     3541 ttttgaaaca aacttctggt ttatgtggga aacaacattt gctttcagaa cacgtagttc
     3601 tgctcaagaa ttgcgtcgct atatgcatca aatgatttat gaattcactc aaatcgaaca
     3661 tctagtgggc gtcaatcgaa cacgttacaa tcaatacgaa agtattatgc ttcctttgat
     3721 cgagtacttg aaagaacaag gatgcaaaat cattttgaac cgccgtgtca ctgactggga
     3781 attcaaagaa acaccgatgc aagatgaaat cactgtgact ggtttgaaaa ttaccaatac
     3841 actgactcaa gaagaagaat acgttgtggt cgatgaagat acagcagtta ttttcactaa
     3901 tgggtccatt acagattcag ctactttagg agattacgaa acaccagctg tagaaaatat
     3961 ggattatggt gcagcttcta gtctctggaa aaaagccagt gaacgtttct acaacttggg
     4021 aaatcctgac aaattctttg ctgatcgaga tgcaagcgaa tgggtcagct ttaccctgac
     4081 gacgaaaaac catttgttgt tgaatgaaat cacccgtatc acgactcaag aaccaggaaa
     4141 tgccttgaat tcatttattt caaccacacc gatcacgccg ttaggccaaa aagatgtcaa
     4201 tatgtctatc gtcgtgcatc atcaaccgca ttttacgtct cagaaaccaa atgaaacagt
     4261 tatttggggt tatttccttt atccaagacg acgtggcgaa tttgtggata aacagtatat
     4321 taaaatgaat ggaaaagaaa tgctagaaga actgattgga caactttcaa aagtagatcc
     4381 tggaccagtg aatattcgtg aaaaagaaac agaaattttc gacagcgtaa taaataatat
     4441 ccctgtctat atgccttatg cttccgcgtt gttcaataat cgtgccaaaa gcgatcgacc
     4501 aaaagtcatt cctaaacatt cgaccaatct ggcctttaca ggagaatttg tcgagcagcc
     4561 ttatcagatg atctttactg aacaaagtgc tgtacgttct ggagaaatcg ctgctttcca
     4621 ttttgcgggt attcctatgt cccgtcttgt caaaacaccg cgttacgaca aagatattcc
     4681 tactctagct cgtgccgcaa aaaaaatgtt tgaataatca agaggttgtg aaaaagctgc
     4741 cctgcatcaa gtaataagaa caaccaggct aaaacagctt cttatgtttt tgatttggtt
     4801 ggacttatta ccgcagatgc aagcttttga acaccgttta ccaagaggtt gtgaaaaagc
     4861 tgccctgcat caagtaataa gaacacccaa gctaaaactg cttcttatgt ttttgacttg
     4921 gttggactta ttaccgcaga tgcaagcttt tgaacaccat ttaccaagag gttatgaaaa
     4981 agctgccctg catcaagtaa taagagcagc caagctaaaa cagcttctta tgtttttgac
     5041 ttggttagac ttattaccgc agatgcaagc ttttgaacac cgtttaccaa gaggttatga
     5101 aaaaggcgtt tagtttcgag tatgaagaaa aattttgtga aaatggttcc tcacgttttt
     5161 gcataaattt gacttaatac cgagaaactg atcccttctg tcataacctc tttttattta
     5221 tgtctgtttc tttttgaaaa caactatttt ttcaacgttt actctcttgc caatccaaca
     5281 tcatctaacg gatacaacta tttcaatgat taccattaca ctaaaaaatc ggaaacacac
     5341 ctctccgaac acaaatacat aagactatag aatgtttcat ttaagaaaaa aagcgtttca
     5401 ttatcaaaaa ggtaagatct cctttaaaat gaaattatct gtagtactaa taatgcagac
     5461 aattttatga atctgaaagg agcatctcca atgaaagcag tcacttggca aggaaaacag
     5521 aaaatggaaa tcagaaacgt agatgatcca aaaatattag aaccaacaga tgcaatcatc
     5581 cgtatcacag caacagccat ttgcggctcc gatctgcatc tttaccatca tggtgaagca
     5641 gttttggaaa aagggtatgt tgtaggacac gaaccaatgg gaatcgttga agaagtggga
     5701 tctcaagttc aaacattgaa aaaagggcaa cgtgtggtta tcccttttaa tattagttgt
     5761 ggtcattgtc atttctgcct gaatcacatg gaaagccaat gtgatgaatc aaatccagat
     5821 cagttatatg gcgggctttt cggatttggc aagttgaacg gtaatcattg gggtggtcaa
     5881 gcggaatatc taagagttcc ttatgcagac tctacttcat ttgttgtacc agataatgat
     5941 cttcctgatg aaaaagtttt atttctatca gatattttgc ccacagctta ttggagcgtt
     6001 gaaaacgcag gagtaaaaaa aggcgataca gttgtgattc taggttctgg tccagtcggt
     6061 ctattcgctc aaaaattcgc tgttatggct ggagcagagc gcgtaatcgc agtagatcca
     6121 gtacagcacc gtctagataa agcggctaat tacaatgggg ttgaaactta tttcttagaa
     6181 gacacggcac aagctggaac agaattgtat gaactggcta aaggtggcgc agatgtcatt
     6241 atcgattgtg taggaatgga cggattagag cctgtcaaag aaaaagcgaa aaatttagta
     6301 agcttacaaa gcggcacaat ctctccatta cagatggcat cgcaagctgt caaaaaattt
     6361 ggaacagtcc aagtaactgg tgtttatatg actccagctt cttcttaccc gctgcaagaa
     6421 ttttttatgc gggatatcgc tgtcaagcat ggacaggcac caattatcca tctaatgcca
     6481 aaaatttacg caatgattgc agaaggacta ttcgatccta cacaaatcat tactcattcg
     6541 ctgccactat cagaagcagc acaagcatat gagatctttg acaaaaaaga agataaaaat
     6601 ataaaagttg ttttgaaacc ttgaattcag taaaaaatac aggtgatttt ctttatgccc
     6661 aaaatcaaac gaaataccca tgagatcgaa ataggaaaag aagaagatat cgaaatacga
     6721 ggacgtcgct tccgcttcta tttccaaaat cgttacacat tgatctcact ggctgtcgat
     6781 ttattaaccg ggattttcta tatttttgga agccttgctt ccttaactaa aatccccgat
     6841 cgatatggca cctattttta tttggctggt gctattttct tgacgattcg tcctattctc
     6901 agaatcgtaa ggaacatttt tatttacgac gaaaaaaaag caatgaagag aacaagcaaa
     6961 aaaaaagagg catgagaatt tttcaaatct catgcctctt ttttcaccct atcgtatcac
     7021 tttgatacag acgagcggtc gtcccacttt cttccttgac cattgtcaaa aatgtccact
     7081 cgtatcgttc ataaaacgtg gtatgatctg taattaagta aagtttttcg tacccaagtt
     7141 gatgcatttc ttttctgatt tccgctaata tccgcttggc tatcccctgc ttacgctttt
     7201 ccggttcaac aaacagggca caaagatttg gtgtcagatc agggcggtta tggaagtcgt
     7261 tttcaatgac gcccgctcct ccgacgatgg tttctttttc atctaagacc acataccatt
     7321 gaggaatact ttccttatta gcgattccag tacgaatact ttcctcatac acaacagcag
     7381 gaactcccca ttttgatgaa aaccaattcg cgctttgttt tactaattct gggtgttctc
     7441 ttaatttgat ccagttatat gtaaccaatg tttaaacctc cgactaaaat aaaacgttta
     7501 caaaaattat acaagtcttt atgaaaatta gcaatgacaa caatagtgat gtaaaaaaaa
     7561 aacggaaaac aatcacttgt tctccgtttt ttgattaatc aagcatctaa agcttctttt
     7621 cttctttctt ggatcgtagc taccttgacg aacggtagat agatcaaaat agaaagaacc
     7681 aaattgacag cggctagtac accacctgca atactttttg ttgccaatac accgccaata
     7741 attggtggag ttacccatgg aggcataacg gtagctgctg gcactaaacc tgtagaagtc
     7801 gcaaagtaag caacactaac taagaccatt ggtgtcaaaa taaatggaat gaacatgatc
     7861 gggttcaaca cgataggtaa cccaaacatc gttggttcat taatattgaa gacacctggc
     7921 gcaatcgaca agtttgttac aaccatatat ggtttgtttt tacgtcctac taaataaata
     7981 gctaacagta aacctaaagt tgcacctgtt cctcctaagt tgacaaagct gtcaaagaaa
     8041 ggtttgttca cgataaacgg tgcgctatgc ccagctgcga ttgcattaac gtttgcttca
     8101 atggctggcg cattgattgt ttgcatcaaa ggatcgacca tattcgctcc gtgtaaacca
     8161 aagaaccata agaatggtgt gataaatgca agcagtaagg cagatggata agagtttgca
     8221 agtcccataa atggttcttg gaccactgta tagaaagaac ctacgatatc atcaacaccg
     8281 aatgcagcaa aaattgcagc aactaaagca aacgcagaga tagtgatcat tgctggtagt
     8341 aatgaagcaa atgcttttgc aactgccggt ggcacaccat caggcatttt gatgatcaat
     8401 ttttcatttc cgcttaaacg tacaaagatt tctgttgaaa taatcccaac aataatagca
     8461 ataaacaaac cgtttgagct catacctaat gctccgccta aagcgaagaa agagcctaaa
     8521 gaaatcacac ctgcggaaac accgtctttt cggtagccgt tagctaaatg ataagcaagc
     8581 aagaaagcaa tcaagacaga aagaatggca aatgtaccgt tccaagcagc agccccgaat
     8641 cctttccatg attcaccacc aaaaattgag ttcatcaatt cttggaaccc gggaatcggt
     8701 aagttattga tcattactgc taatgctcct aagatcatta acggcatact caccataaat
     8761 gagtcccgaa tcgcaactaa atgccgttgt gcaccaattt ttgatgctac aggtataaaa
     8821 tgtttctcca taaatgcaac aaatttatcc ataaatcttc cctcttttct ttactgtaga
     8881 ttacgcgttc aatcgacgat acagatcaat gatctctttt gctaaatctg taaaagctat
     8941 agatgtcatc agatgatctt gactgtggac cgtcaaaagc gtgacttcaa cgtgatttcc
     9001 ttgtgcttct tgtgtcagca tctctgtttg agagtgatgt gcttggacta aagattcctc
     9061 tgcatctttg attttttcat ctgctaaagt gaaatcacct tttttcgcag cagcaatcgc
     9121 ttccattgca tcgctttttg catttccgcc aaacatgatc agacccatga tggcttctag
     9181 atttttttga tcttccattt attgtatcct ccgataattt ttattatttg tttattagtt
     9241 tttctgcttg gtcgagtact ttttcaccat tcatcatgcc atagtcagcc atattgatta
     9301 catctaaagg aatgccttta ggtgctagct tttcagcaaa ttgattttgc ataaagcgta
     9361 cttgcggtcc taaaagtaaa acgtctacat ttttagattc tagttgatta tccgcatctg
     9421 aagcagatac agcaaagatg tctgcttcca ttccttttgc ttctgctgcc ttttgcattt
     9481 ttgtgactag gagacttgta ctcattccag ctgaacatac aagcatgatt gttttctttt
     9541 ccattttaaa cacgttcctt tctatactta cacttgtata taagcaagta gcgtgccaac
     9601 tttaaaagcg ctttaaaaag ttgatatcat cacatttaag gtctatacca agttgcatac
     9661 acactaaaaa agaaagcgca cactaaacac acaaattaat ttttattacc ttttttcttt
     9721 taacgtgcac aaaaaaagtt gtgacacaaa acttgtcaca acttttttca aataaacggt
     9781 attcaaaagc ttgcatctgc ggtaataagt ccaaccaagt taaaaacata agatgttgtt
     9841 tttactttgc tattcttatt acttgatgca ggacagcttt ttcacaacct ctcaataaac
     9901 ggtgttcaat cagctgaccc tgggtattag ctcaaaacgc tggattcaca acctctttta
     9961 tttcaaataa ccagtaaata caatgaacat ctacaaaaaa cttctattta tttatagatt
    10021 tcgtcaggca aatccaattc tctcttatca atcaaagtct gataccacga agcagatttt
    10081 ttcaatgttc tgcttcgttc atcgttcaat tcgattcgaa ctaatccata tcgattctta
    10141 aatgcattca ttggtgacac acagtcagtg aatgcccata acatatagcc ttcgcaattt
    10201 gcgccttctt ctgttgcttt gatcaagtaa tgcaaatgct gtccgataaa ttcgatacgg
    10261 taatcatctt gcacgattcc tttctcatcc atatactgtt cttcatattc tcttcccata
    10321 ccgttttctg ttatcagcca agggatatta tgataatttt cttttagata catggctata
    10381 tcatacatga ttttcggata gatttcccat cccctggaat tattcatttt cttcccaggt
    10441 aaatcaaaga cttcataata tcgttcagga tggaaaggtg tctcttcatt ccattgataa
    10501 cgaggggcgc gaacgcgttt aggataatat tgattgattc caaggaaatc tactgtatga
    10561 tgctgaatcg tttctaaatc ctctgttgca ggatcgaaat aaatcgattg tttttgacac
    10621 aactccagga actcttctgt gtagtatcct tttaccatcg gatcaaaaaa tactcgatta
    10681 taaaacaaat catacatata agcagctttt tggtcttctg gagaattgga tcgagcatag
    10741 accatttcag gatttaaaat acagccaatc cttccaccat aatttccgct gcggtaaatc
    10801 tctactgctt tagccgttgc taaaacttta tgataattcc acatcatcca cttttttgtg
    10861 ttttgttcat gcggccagcg aacagcatcc aaatagcaac gcgtttgggg aacgattggt
    10921 tcgttgaatg taaaccagtt ttttacccta tcaccgtaac gatcaaaggc aatttgagca
    10981 tacttagcat aaaaatcaac tacttttctt gaagaccagc catcatattt ttccaaaaga
    11041 aaagctggga cttcataatg ttccaaacaa atcatcggtt ctacgtctgc ttcgatcaaa
    11101 gagtcgatca tttcacttat atgctgagca tattcttcat ctactataca gttctcataa
    11161 tcagtaaaaa aacgagccca attgatagaa gtccgataat gtgtcagatg gatggatttc
    11221 atcagatcca catcctgctg gtattgttcc ataaaattag ttgctacggc tgggccatac
    11281 ccattatgcc aaacaaaatg ttcattttta taccagctat ctataaacga atcctgtcct
    11341 tctttttttc ctttccaacc ttccgtttgc caagcagaag atgcagcacc aagaataaaa
    11401 ttttttggaa tagtaatttt catgatttcc tcctgttttt tagatcccat cattttccac
    11461 acgatttgct acttttacaa atggcagata gatcaaaata gaaacaataa tacaaacaag
    11521 ttgcgtaata actgcaccga tatttcctgc tgttgccaga taagcattga cgatcggcgg
    11581 cattggccaa gggaccatta caactgcttt cgccgcaaat cctaaagcgg ttgcaaaata
    11641 accaatcgtt ccagtgataa gaggcgttaa gataaacgga atagctaaaa ttggattcag
    11701 catgatcggc ataccaaaaa taactggttc attgatgttg aagatcccag gagcaaggga
    11761 taacttggtg atttgtttca tatcttcccg ttttccaact aacaatactg caatcagtaa
    11821 accgatcgtg actccagacc cgcccatact catatacata tcccaaaatg gcatagtaat
    11881 aatgttcggt acttcttttc cagcttcaaa agcttccgta tttacagcaa ttgccgctaa
    11941 aagcaacggt tcccgtatcg gcttcaccat ttgatttcca tggataccaa tcacccaaaa
    12001 gacttgcgca ataaacatca atagcaaaat acccggtaac ccttgtacga caccttctaa
    12061 tgggcgttgt acgacattgt aaatgatatc ataaaggtac attcctgtaa gttctttgat
    12121 gataaatccc gcagccgcga tacccgatac agtcagaatc gtcgggaata aagcagaaaa
    12181 actagcagaa acattcgttg gcacggtatc aggcattctc agctgtagtt tcttctgttt
    12241 cctcaaccag caataaagtt caatagaaag gatggagacc aacattccca aaaataaccc
    12301 tttcgtatct gtatattgtt tagccaatac gttttctact ataacagtct gattttcatt
    12361 cactaattca taaacagttg gattaacaga taaataagac atcactgcga tgataccagg
    12421 gaatacacca tccactttat tcagcttggc taattcgatc cctatcagaa aaacagtata
    12481 gatggtcaag aaacttagtg tgacatagct gatggcagat gcgataggct ttaattcttc
    12541 taaaaaacgc aagaaactta tctgtgctaa gccattttcc gagtcaaaga ccattgctga
    12601 aaacaatgtg ccaaaagcac ccgtaataat taccggaatc aatgcagcaa atgcgttttt
    12661 tatcaccatg atatacctta aattattgat tctcgttgcc acgttcccta aaacattggc
    12721 taatttatcc ataaaactca ttccagatcc cctcattcct gcttcttctc cttgacgtca
    12781 tctctttttg tctattagtc agcgcttaca tttcgatgaa cagaaactat ttactcctct
    12841 tttttaccaa atataaaaca aaaattcatc tgatgtattt atcataaaat acatcagatg
    12901 aactgtcaat tagtttcttt ttctcctatt attttctgta attctctccg atttattgcc
    12961 atatggacag tcattgcatc aaacgcagca agtgcattcc gcctttcgat ggcctgaacg
    13021 atctctgtat gaatatcgat cgtctcgatt ttcagatgct ggatatcata atttttatta
    13081 aacaaagcaa ttgattcatt aatgattggg ataatatgca gcaaggctac gtttccgcta
    13141 gcttctgcaa tcatcgtatg aaaatcgatg tctaattgaa catgttcttg tgtgccttct
    13201 cgaaaagaag tttcaatctt ttgcgttaat tttttcattt ggacgatttg attcttcgtt
    13261 gcatattccg ctgccaaacc tgccatctta ggctccaata aatatctcag ttcaaataag
    13321 tctcgtatca tccgatcctg atcttcaatc aaagaaaaac cgagtgggtc attggcaatc
    13381 cctcgcttat cactgacaaa tgtccccgct ccttgccgaa cttcaaggat attcctggaa
    13441 gctagagccc gcacagcttc tcgcaccgtg cttcgcccca cctctaaata atcggacaat
    13501 tcatattcat tcggcagttt atctcctact tgcaactgca tttcctttaa atatctaagg
    13561 atcttgtcag tagttacttc tactagggtt ttattttctt ccaaaccaca tacctccttt
    13621 tcatctgatg tattttttcg taattattat aacacgtttg aatcatctga tgattttttg
    13681 tatacaaaat tgattaatcc gttcatagac atacaaacga agaagatatt taccataaaa
    13741 aagactagga
//
LOCUS       DAZKPE010000073        13677 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000073 DAZKPE010000000
VERSION     DAZKPE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.073"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            53..295
                     /gene="yaaA"
                     /locus_tag="ACG930_002341"
     CDS             53..295
                     /gene="yaaA"
                     /locus_tag="ACG930_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFQ0519492.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            282..1406
                     /gene="recF"
                     /locus_tag="ACG930_002342"
     CDS             282..1406
                     /gene="recF"
                     /locus_tag="ACG930_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFQ0519493.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1403..3349
                     /gene="gyrB"
                     /locus_tag="ACG930_002343"
     CDS             1403..3349
                     /gene="gyrB"
                     /locus_tag="ACG930_002343"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFQ0519494.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3369..5840
                     /gene="gyrA"
                     /locus_tag="ACG930_002344"
     CDS             3369..5840
                     /gene="gyrA"
                     /locus_tag="ACG930_002344"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFQ0519495.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6076..6375
                     /gene="rpsF"
                     /locus_tag="ACG930_002345"
     CDS             6076..6375
                     /gene="rpsF"
                     /locus_tag="ACG930_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFQ0519496.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6425..6937
                     /gene="ssb"
                     /locus_tag="ACG930_002346"
     CDS             6425..6937
                     /gene="ssb"
                     /locus_tag="ACG930_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0519497.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6963..7199
                     /gene="rpsR"
                     /locus_tag="ACG930_002347"
     CDS             6963..7199
                     /gene="rpsR"
                     /locus_tag="ACG930_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFQ0519498.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7342..9315
                     /locus_tag="ACG930_002348"
     CDS             7342..9315
                     /locus_tag="ACG930_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFQ0519499.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9321..9773
                     /gene="rplI"
                     /locus_tag="ACG930_002349"
     CDS             9321..9773
                     /gene="rplI"
                     /locus_tag="ACG930_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFQ0519500.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10047..11414
                     /gene="dnaB"
                     /locus_tag="ACG930_002350"
     CDS             10047..11414
                     /gene="dnaB"
                     /locus_tag="ACG930_002350"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFQ0519501.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12194..13486
                     /locus_tag="ACG930_002351"
     CDS             12194..13486
                     /locus_tag="ACG930_002351"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFQ0519502.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4556 a         2472 c         3013 g         3636 t
ORIGIN      
        1 aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg cattgaaaca
       61 acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag aagtcacagt
      121 tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt tagtcgatgg
      181 cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg aagttccaga
      241 agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg aataagctgt
      301 atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag aacctcgtca
      361 tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc tacgtattag
      421 ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg actgacgatc
      481 aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta gaaatcttat
      541 tatctaaaaa aggccgaaaa accaagatca accatatcga acaaaaaaag ttaagtactt
      601 acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta gtaaaaggca
      661 gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat ccaatctatc
      721 tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtat ttaaagcaat
      781 tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa caactagcag
      841 cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg gagttttggg
      901 ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc gagtatctca
      961 ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa tttctcgcac
     1021 ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt ggtcctcatc
     1081 gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga tcgcaaggac
     1141 agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt aaagaagaga
     1201 cgggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat gatagtcgtc
     1261 aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca acaacgacac
     1321 ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt caacaaggga
     1381 aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac gcgctaaaga
     1441 gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta aacgacctgg
     1501 catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg aaattgtcga
     1561 taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga ttattgaaaa
     1621 agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata tccaggcaaa
     1681 aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag gaaaattcgg
     1741 cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg ttgttaacgc
     1801 gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact atcaagaata
     1861 tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc gccatggaac
     1921 aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt ttgatttttc
     1981 aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc gtatatcgat
     2041 tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg gcgggattaa
     2101 aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac ctgtatattt
     2161 ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag acggctacca
     2221 ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa cacatgaatc
     2281 aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac aaaagctgat
     2341 gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga cagctgttat
     2401 ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat tgggcaattc
     2461 cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat tcttgctgga
     2521 aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca gagctcgtct
     2581 agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga ttagtaatct
     2641 gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat tgttcatcgt
     2701 cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt ttcaagccat
     2761 cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca agatcttggc
     2821 aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag aagattttga
     2881 tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg tcgacggcgc
     2941 gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta ttgttgaagc
     3001 tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga agaatattac
     3061 gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg cttcacttcc
     3121 tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg atgatcatca
     3181 actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca gtgtggacga
     3241 tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag aaccccgtcg
     3301 tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat catgaaggag
     3361 gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta accagcgaaa
     3421 tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca cttcctgatg
     3481 tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac gaattaggtg
     3541 taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc atgggtaaat
     3601 accatcctca tggagactat gcgatctatg agtcaatggt acggatggca cagccattca
     3661 gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac ggtgacggtg
     3721 ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa atgctgcgtg
     3781 atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa aaagaaccag
     3841 ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg atcgccgtag
     3901 gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct atcgatttgc
     3961 tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct ggaccagatt
     4021 ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat gaaacaggta
     4081 agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat ggtaaagaac
     4141 ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc gaacggattt
     4201 ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac gaatcttccc
     4261 gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct gttatcttga
     4321 ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg ttggcgatcg
     4381 aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat atcgaacatc
     4441 agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa gcaagggcac
     4501 acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt gcgattatcc
     4561 gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc gatttatccg
     4621 atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt ttggaacggg
     4681 aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta actgacattc
     4741 tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac ttgaatcaac
     4801 gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt ctggaagatg
     4861 aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt tacatcaaac
     4921 gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc caaggaatgg
     4981 gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat gatacattgt
     5041 tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt ccagaatacg
     5101 ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg agtgaaagca
     5161 tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc ttctttacga
     5221 cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc cgaagtaatg
     5281 gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta ctgacagatg
     5341 gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc aaagaagaag
     5401 cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg cgtgaggaag
     5461 attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg atcacagaaa
     5521 aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc ggaggtaaag
     5581 ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg accactgttt
     5641 ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt ttcaacgtat
     5701 cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag atggaagctg
     5761 atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa acagttgaag
     5821 aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag aatgaccgat
     5881 taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct taaaatattc
     5941 gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag agcttgtgag
     6001 tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg aaagtccaca
     6061 gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat tcgtccaaac
     6121 attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt gaaagataac
     6181 ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta tgaaatgaac
     6241 ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc agcaaatgct
     6301 gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca catgattgtt
     6361 aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag aggagatgac
     6421 tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag atttgcgtta
     6481 cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta attttacaaa
     6541 ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca aatcagcaga
     6601 aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac gtatccaaac
     6661 tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag tagctgacaa
     6721 cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg gcggattcca
     6781 aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc aaacatctca
     6841 atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg gctcaagttc
     6901 aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag gagggaaata
     6961 gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac attgctgcta
     7021 accatattga atatatcgat tataaagata tcgaattact aaaaagattt atttcagaac
     7081 gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa cgtaaaatta
     7141 ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc gaagactaat
     7201 aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct ttttttctgt
     7261 aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa aatcaaatta
     7321 gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc gaaacctctc
     7381 ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc atttcgtttt
     7441 gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg gttgaaaatg
     7501 aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac tgtagctgaa
     7561 accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta tcagccatca
     7621 agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca aagtggatta
     7681 acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa aaaccaagtc
     7741 tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt tgtttatttt
     7801 aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca gccggtgatt
     7861 ggtattttat ctattgataa ctatgcagat gccattgata aattggatga caaagagatt
     7921 tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga ataccatgtc
     7981 tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat cgatctgaaa
     8041 aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc tgaaaaacag
     8101 agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct cgatgaaatc
     8161 ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga ccaagttgtc
     8221 gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc tgctaagaat
     8281 gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg gatttttgat
     8341 gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc tttaggctct
     8401 gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat cgttatcaac
     8461 gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa gcatcctgaa
     8521 ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga agaggacctc
     8581 ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct atatgagcaa
     8641 tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc aagtaaacct
     8701 ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc tgagctgatc
     8761 caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt attgcttgca
     8821 gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac ttttgacgtt
     8881 gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt attgagctcg
     8941 gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta tgtgacttct
     9001 gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat agcagcaaaa
     9061 acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat tacaaagcgg
     9121 acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt ccaaatcatc
     9181 atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact ggaaaatacg
     9241 acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat gaatcaaata
     9301 tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa ggaaaaggta
     9361 aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta atcaaaaata
     9421 acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa aagaaagcac
     9481 aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa ttcttggaaa
     9541 aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt ttgtttggtt
     9601 cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc aaattagata
     9661 aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac gtacctgtta
     9721 agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa taacaaatct
     9781 tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac cgaaatttat
     9841 ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag attgatttcg
     9901 gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa aagagaacta
     9961 tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt gtaaaatgaa
    10021 gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga atcccaccgc
    10081 aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca gaaacgatca
    10141 ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat caaattattt
    10201 ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt actgtcaaag
    10261 accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat ctctcagact
    10321 tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc gttgaagaaa
    10381 aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa ggattcgagc
    10441 aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg gaggtttcgg
    10501 aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc acgattgaaa
    10561 atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact ggctatcaag
    10621 gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt gctgcacgtc
    10681 cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga acaaaaacag
    10741 atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta aatcggatgc
    10801 tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt tcggaagaag
    10861 aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt tttatcgatg
    10921 atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta gcgcaagaaa
    10981 aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt aacggtaaag
    11041 agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg gcgaaagagc
    11101 tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag cgacaagaca
    11161 aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat gcggacatcg
    11221 tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac gatgatggaa
    11281 acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga agcggtgcac
    11341 gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg ctttcgccaa
    11401 gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct ctcgtaagaa
    11461 gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat ctccaaaggg
    11521 attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc aatcagctga
    11581 cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg tttgtttctc
    11641 taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt gttctcctgc
    11701 caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt ttgaaattgc
    11761 tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg gtgttcaaaa
    11821 gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta tttttgtttg
    11881 gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca cggtgttcca
    11941 aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag caattttcgt
    12001 acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt ttaataacca
    12061 ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata aaaatcattc
    12121 gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa ataatataga
    12181 acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg atgaagggaa
    12241 aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt accaaggtgg
    12301 cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc atttgattcc
    12361 ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg tagtcaatcc
    12421 taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa caagtaattt
    12481 gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg accaattaca
    12541 agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg gacctgccta
    12601 tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata aagaaatttt
    12661 tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa aaatgtttga
    12721 ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg gacaacaaat
    12781 caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg caggcaaacg
    12841 cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa cttatccttt
    12901 tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg tagggccttc
    12961 aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg gtgatggacc
    13021 atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag gacgagaata
    13081 cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag ttatgcgcca
    13141 ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg tattaagtgg
    13201 attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa tctaccacta
    13261 tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat tgccaggctg
    13321 gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg cacgtaacta
    13381 tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg tcggacctga
    13441 tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat aaaaacgacg
    13501 actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg ataataataa
    13561 cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc tcttgaacac
    13621 tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt ttccgaa
//
LOCUS       DAZKPE010000074        13148 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000074 DAZKPE010000000
VERSION     DAZKPE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.074"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..150)
                     /locus_tag="ACG930_002352"
     tRNA            complement(78..150)
                     /locus_tag="ACG930_002352"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115..117),aa:Lys,seq:ctt)
     gene            531..1100
                     /locus_tag="ACG930_002353"
     CDS             531..1100
                     /locus_tag="ACG930_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFQ0519503.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1087..1947
                     /locus_tag="ACG930_002354"
     CDS             1087..1947
                     /locus_tag="ACG930_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFQ0519504.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2137..2841
                     /gene="yycF"
                     /locus_tag="ACG930_002355"
     CDS             2137..2841
                     /gene="yycF"
                     /locus_tag="ACG930_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFQ0519505.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2846..4681
                     /gene="walK"
                     /locus_tag="ACG930_002356"
     CDS             2846..4681
                     /gene="walK"
                     /locus_tag="ACG930_002356"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFQ0519506.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4678..5994
                     /locus_tag="ACG930_002357"
     CDS             4678..5994
                     /locus_tag="ACG930_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YycH family regulatory protein"
                     /protein_id="HFQ0519507.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQMPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5995..6864
                     /locus_tag="ACG930_002358"
     CDS             5995..6864
                     /locus_tag="ACG930_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFQ0519508.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6919..7728
                     /locus_tag="ACG930_002359"
     CDS             6919..7728
                     /locus_tag="ACG930_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFQ0519509.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7831..8460)
                     /locus_tag="ACG930_002360"
     CDS             complement(7831..8460)
                     /locus_tag="ACG930_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0519510.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8630..9922
                     /locus_tag="ACG930_002361"
     CDS             8630..9922
                     /locus_tag="ACG930_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0519511.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9998..10660)
                     /locus_tag="ACG930_002362"
     CDS             complement(9998..10660)
                     /locus_tag="ACG930_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFQ0519512.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10885..11169
                     /gene="groES"
                     /locus_tag="ACG930_002363"
     CDS             10885..11169
                     /gene="groES"
                     /locus_tag="ACG930_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFQ0519513.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11220..12845
                     /gene="groL"
                     /locus_tag="ACG930_002364"
     CDS             11220..12845
                     /gene="groL"
                     /locus_tag="ACG930_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFQ0519514.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4372 a         2265 c         2832 g         3679 t
ORIGIN      
        1 ataaaaaaag aacagcgtaa atgttttcga aatgctttcg caccaacatt tacctgttcc
       61 gtgggtttgg cacccaatgg gccgtgaggg gctcgaaccc gcgacccgct gattaagagt
      121 cagctgctct accaactgag ctaacggccc gtacaaaaag tacttaataa tagtagcact
      181 aagaatttta aaatgcaaga ctacatttaa agaaaatcag aaaaatcttt acttccttat
      241 aggaaatcat tcatagatta ttcacatttg ctcgctatta tataagcata ccaacaaaca
      301 aagttcttgc aagagaacaa accctaacac ttttttcatt ttttactcct ttcccgccgt
      361 ctccccggcg ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt
      421 tttgttttca tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt
      481 tatcataagt ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa
      541 tgcgtcagca attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg
      601 aagaactccc tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc
      661 tttcacctgt gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt
      721 acgttaaact aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag
      781 catttttact tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag
      841 ggatattgtt ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg
      901 aacaagaagc agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa
      961 aattcgacca ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg
     1021 caatgaaact tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga
     1081 aaacaaatga aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa
     1141 gaattgataa aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag
     1201 gtatatacag ataaaattga cattacctct gaagagatct atcaacgttt gccagaggaa
     1261 atccctggta catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa
     1321 aaagacggtt atgaaaaggt acttgcggta acaatttcca gtggattgag cgggacatat
     1381 aatgtggttc gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg
     1441 aaaaatattg gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa
     1501 ggagtagaat gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt
     1561 ttctttaatg ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct
     1621 tctattgtag gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt
     1681 tattacacag taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac
     1741 gtcaaagaaa aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg
     1801 aaagaagaag caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa
     1861 atctactttg gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt
     1921 gtcggtgtac aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag
     1981 tgttttcctt ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt
     2041 taattttctc ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga
     2101 gaaggtatga caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat
     2161 gatgagaagc cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt
     2221 tatactgcat atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg
     2281 attttacttg atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc
     2341 aaaacttatg atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc
     2401 ctaggcttag agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta
     2461 gttgcacgtg tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag
     2521 gcagcacctg cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg
     2581 acgaaacgag gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg
     2641 gcgaagcacc ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat
     2701 gattattttg gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc
     2761 gaagataatc caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg
     2821 cgtaacccag aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa
     2881 ttttaagatc gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc
     2941 ctactttata cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca
     3001 aacggtggaa tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga
     3061 tgatgaagag gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat
     3121 catcgaaata cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga
     3181 acaaagcgct gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg
     3241 ttatgttgct ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc
     3301 cccgaccggc gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata
     3361 ttcggaaatc aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat
     3421 ttcaatgatc gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag
     3481 agaacaagcc attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca
     3541 agatgaactt ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc
     3601 tcaagataca atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga
     3661 cggcgtcatt gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc
     3721 cttgctagat atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat
     3781 cgaagaagaa tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg
     3841 ttcaaccagt acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg
     3901 tcgcgaatca ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga
     3961 aaaaacagaa cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc
     4021 gttgacaagt atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga
     4081 agtagcacca aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat
     4141 caatgacctc ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata
     4201 tgtcaatttc aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa
     4261 tcaggaaaaa aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt
     4321 agatacagat aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc
     4381 accagatggg ggaacgatta cttgtcgctt attagaaacg cataataacg tggttttaag
     4441 tatcaccgat caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt
     4501 ctatcgagta gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat
     4561 ttctagagaa gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa
     4621 agggtcgact ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg
     4681 agaatctctg aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac
     4741 ttctcttatg caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca
     4801 aacactcaaa tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt
     4861 catgttacat ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac
     4921 cgattgcaat tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga
     4981 gacaaatcac agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat
     5041 gcgccttttt tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac
     5101 ttggcaaaag aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa
     5161 aaaatccgat ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat
     5221 tggacagata tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca
     5281 gaaccatcga cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat
     5341 agttatatcc tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca
     5401 gatagcgtga aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca
     5461 atgtctatcc attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa
     5521 gaaaatgcta gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta
     5581 gggaacctca gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa
     5641 ggcttcccgg tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa
     5701 acgaatggtt ctgtgcaagt gaatatccaa accagtttga atacgattca aatgccgata
     5761 ccttcagacg aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct
     5821 aagggagcag atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc
     5881 aaagaaacga atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac
     5941 tggtattcag ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat
     6001 ttcaaaaaaa tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc
     6061 agcagttatc atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa
     6121 tcaatccaac aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag
     6181 aacaagcaag gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat
     6241 tatcgcaagg ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt
     6301 ttgacgaaat ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt
     6361 agtagttcct tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat
     6421 gtgtacacga aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa
     6481 gagtatgaag gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa
     6541 aacgataatg attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag
     6601 ctgcgcgaaa agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat
     6661 aacaaaatac caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg
     6721 aaagtccggg aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat
     6781 aaagtggtcc aaattgagag tgtcaacgct ttcagcaata cgatcgtgac aaacaatact
     6841 gtaccaaaag tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag
     6901 aagggaagta ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca
     6961 agtggaagtt cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat
     7021 gcaggactta gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac
     7081 caattagatg gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc
     7141 ttggctcgta agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa
     7201 ccactgattg gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga
     7261 acattcggcg atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa
     7321 ttttatcgtt tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc
     7381 agtgattata tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat
     7441 gatcttgaga tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga
     7501 gatagaggac atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat
     7561 cggaccaaac gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct
     7621 catttaacaa tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa
     7681 atctatgata cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca
     7741 ataaaaatat aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta
     7801 tttttttagc atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt
     7861 ttcatgtttc tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat
     7921 cgtactgtcg ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt
     7981 acgtttgcca tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt
     8041 agattgtttc aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc
     8101 atttttaggt acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga
     8161 ggcaccccca acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga
     8221 caaagaagtt tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac
     8281 atcaaaagat gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac
     8341 atctgatggc aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa
     8401 tgcttcgtct aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat
     8461 aaaaaacctc cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa
     8521 tccgattttt gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt
     8581 taaattaaga aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg
     8641 gttagatcgt gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc
     8701 tttgcgtaat ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt
     8761 atttgctcat tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat
     8821 gtattttaca caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc
     8881 cattgcatac gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc
     8941 cttgtctgct tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac
     9001 aggtgctgaa gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc
     9061 acgtttagta agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg
     9121 gcagtctttt acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc
     9181 agcggttttt caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca
     9241 gcttcccatt caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt
     9301 tccgttttta tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc
     9361 cgtcttgcaa gcgaattcat tagcgaatgc agaaatctta gcctcaggac aagagttgac
     9421 ggtggcaaat ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac
     9481 gggtgctgga ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa
     9541 atacagagaa ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat
     9601 tattttttcc acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc
     9661 ggtcgtttca ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac
     9721 agcagtccaa gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt
     9781 gcctgcagcg attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt
     9841 tttgaaaaaa atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc
     9901 agcagaaaag atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat
     9961 caccaatcta ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag
    10021 ctaattgaac aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga
    10081 tccgaccagt tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca
    10141 gatgaccatc attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa
    10201 aatttgaata tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga
    10261 tgggtccagc aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga
    10321 tattttgtgt attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag
    10381 cgatgctttg cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg
    10441 gagcagaagc tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa
    10501 aaatagctag gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag
    10561 acgtagattt tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat
    10621 agcaaaaaat gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg
    10681 ataacaagca tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata
    10741 agcagctgtc agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga
    10801 atgagtatta ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa
    10861 aaagagttat cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa
    10921 gtcgcaaaag aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag
    10981 aaaccccaaa ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa
    11041 aaagttcctg ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca
    11101 gaagtaaaat acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt
    11161 gttgagtaaa tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca
    11221 tggcaaaaga attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata
    11281 aattagcaga tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa
    11341 aatcttacgg ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat
    11401 tagaagatca ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa
    11461 atgatattgc aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg
    11521 aaggtttaaa aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat
    11581 tggcaacaaa agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag
    11641 aagccattgc acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg
    11701 ctgatgcaat ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga
    11761 tcgaaacaga actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat
    11821 atatggtaac agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca
    11881 cagacaaaaa aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac
    11941 aatcacgtcc attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg
    12001 tattgaacaa aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg
    12061 atcgtcgtaa agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg
    12121 acgatctagg tttagaattg aaagatgtaa caatcgaaaa cttaggaaat gcttctaaag
    12181 ttgttgtaga taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg
    12241 aagctcgtgt gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg
    12301 aaaaattaca agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg
    12361 cagctactga aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta
    12421 cacgtgccgc agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta
    12481 tcagcaaagt ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg
    12541 ttcgtgcttt agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag
    12601 tgattgttga taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag
    12661 aatgggtaaa catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct
    12721 tgcaaaatgc cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata
    12781 aaccagaacc agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggtatga
    12841 tgtaagaaaa agcaacttgc ttatctacaa ctgatcatta gtgaaagaca gataaaaaga
    12901 ggctggaaca gaagcgttta actccaagaa ataagaagaa attcacggaa attgcttttc
    12961 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ctgtttatac
    13021 gtgtttagag cgtgagacaa aagtgttctt tacttttgtc ccacgctctt ttttgtgtgt
    13081 aattataatg aaaatagtta tttttaatag ttataatatt ttatctatta aaagtaaata
    13141 tccattca
//
LOCUS       DAZKPE010000075        12909 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000075 DAZKPE010000000
VERSION     DAZKPE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.075"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..3660
                     /locus_tag="ACG930_002365"
     CDS             133..3660
                     /locus_tag="ACG930_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFQ0519515.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACG930_002366"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACG930_002366"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFQ0519516.1"
                     /translation="MNQIPLKTQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACG930_002367"
     CDS             7448..7789
                     /locus_tag="ACG930_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFQ0519517.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACG930_002368"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACG930_002368"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFQ0519518.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACG930_002369"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACG930_002369"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFQ0519519.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG930_002370"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG930_002370"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFQ0519520.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4386 a         2241 c         2739 g         3543 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaacg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaa
//
LOCUS       DAZKPE010000076        12655 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000076 DAZKPE010000000
VERSION     DAZKPE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.076"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..875
                     /locus_tag="ACG930_002371"
     CDS             <1..875
                     /locus_tag="ACG930_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFQ0519521.1"
                     /translation="LNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTREKIIKIF
                     DKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIEEEKVRR
                     EIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKELEVIRE
                     NVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPFEFDVHA
                     MIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTVTFTKLA
                     KAEQYRRSLELSKD"
     gene            947..2068
                     /locus_tag="ACG930_002372"
     CDS             947..2068
                     /locus_tag="ACG930_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0519522.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(2150..3922)
                     /locus_tag="ACG930_002373"
     CDS             complement(2150..3922)
                     /locus_tag="ACG930_002373"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519523.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(3925..5637)
                     /locus_tag="ACG930_002374"
     CDS             complement(3925..5637)
                     /locus_tag="ACG930_002374"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519524.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            5752..6420
                     /locus_tag="ACG930_002375"
     CDS             5752..6420
                     /locus_tag="ACG930_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFQ0519525.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(6487..7275)
                     /locus_tag="ACG930_002376"
     CDS             complement(6487..7275)
                     /locus_tag="ACG930_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0519526.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(7358..8830)
                     /locus_tag="ACG930_002377"
     CDS             complement(7358..8830)
                     /locus_tag="ACG930_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFQ0519527.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(8960..10153)
                     /gene="metK"
                     /locus_tag="ACG930_002378"
     CDS             complement(8960..10153)
                     /gene="metK"
                     /locus_tag="ACG930_002378"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFQ0519528.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     regulatory      complement(10151..10230)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            complement(10419..10490)
                     /locus_tag="ACG930_002379"
     tRNA            complement(10419..10490)
                     /locus_tag="ACG930_002379"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10455..10457),aa:Glu,seq:ttc)
     gene            complement(10502..10575)
                     /locus_tag="ACG930_002380"
     tRNA            complement(10502..10575)
                     /locus_tag="ACG930_002380"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10539..10541),aa:Ile,seq:gat)
     gene            complement(10588..10658)
                     /locus_tag="ACG930_002381"
     tRNA            complement(10588..10658)
                     /locus_tag="ACG930_002381"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10624..10626),aa:Gly,seq:tcc)
     gene            complement(10663..10735)
                     /locus_tag="ACG930_002382"
     tRNA            complement(10663..10735)
                     /locus_tag="ACG930_002382"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10700..10702),aa:Phe,seq:gaa)
     gene            complement(10739..10811)
                     /locus_tag="ACG930_002383"
     tRNA            complement(10739..10811)
                     /locus_tag="ACG930_002383"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10776..10778),aa:Asp,seq:gtc)
     gene            complement(10830..10903)
                     /locus_tag="ACG930_002384"
     tRNA            complement(10830..10903)
                     /locus_tag="ACG930_002384"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10867..10869),aa:Met,seq:cat)
     gene            complement(10916..11005)
                     /locus_tag="ACG930_002385"
     tRNA            complement(10916..11005)
                     /locus_tag="ACG930_002385"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10967..10969),aa:Ser,seq:tga)
     gene            complement(11028..11099)
                     /locus_tag="ACG930_002386"
     tRNA            complement(11028..11099)
                     /locus_tag="ACG930_002386"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11064..11066),aa:Glu,seq:ttc)
     gene            complement(11121..11208)
                     /locus_tag="ACG930_002387"
     tRNA            complement(11121..11208)
                     /locus_tag="ACG930_002387"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11172..11174),aa:Ser,seq:gct)
     gene            complement(11233..11306)
                     /locus_tag="ACG930_002388"
     tRNA            complement(11233..11306)
                     /locus_tag="ACG930_002388"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11270..11272),aa:Ile,seq:gat)
     gene            complement(11320..11390)
                     /locus_tag="ACG930_002389"
     tRNA            complement(11320..11390)
                     /locus_tag="ACG930_002389"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11356..11358),aa:Gly,seq:tcc)
     gene            complement(11392..11467)
                     /locus_tag="ACG930_002390"
     tRNA            complement(11392..11467)
                     /locus_tag="ACG930_002390"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11432..11434),aa:Asp,seq:gtc)
     gene            complement(11486..11559)
                     /locus_tag="ACG930_002391"
     tRNA            complement(11486..11559)
                     /locus_tag="ACG930_002391"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11523..11525),aa:Met,seq:cat)
     gene            complement(11572..11661)
                     /locus_tag="ACG930_002392"
     tRNA            complement(11572..11661)
                     /locus_tag="ACG930_002392"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11623..11625),aa:Ser,seq:tga)
     gene            complement(11685..11758)
                     /locus_tag="ACG930_002393"
     tRNA            complement(11685..11758)
                     /locus_tag="ACG930_002393"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11722..11724),aa:Ile,seq:cat)
     gene            complement(11772..11845)
                     /locus_tag="ACG930_002394"
     tRNA            complement(11772..11845)
                     /locus_tag="ACG930_002394"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11809..11811),aa:Met,seq:cat)
     gene            complement(11873..11945)
                     /locus_tag="ACG930_002395"
     tRNA            complement(11873..11945)
                     /locus_tag="ACG930_002395"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11910..11912),aa:Ala,seq:tgc)
     gene            complement(11965..12038)
                     /locus_tag="ACG930_002396"
     tRNA            complement(11965..12038)
                     /locus_tag="ACG930_002396"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12002..12004),aa:Pro,seq:tgg)
     gene            complement(12048..12121)
                     /locus_tag="ACG930_002397"
     tRNA            complement(12048..12121)
                     /locus_tag="ACG930_002397"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12085..12087),aa:Arg,seq:acg)
     gene            complement(12132..12217)
                     /locus_tag="ACG930_002398"
     tRNA            complement(12132..12217)
                     /locus_tag="ACG930_002398"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12181..12183),aa:Leu,seq:taa)
     gene            complement(12234..12305)
                     /locus_tag="ACG930_002399"
     tRNA            complement(12234..12305)
                     /locus_tag="ACG930_002399"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12271..12273),aa:Gly,seq:gcc)
     gene            complement(12317..12389)
                     /locus_tag="ACG930_002400"
     tRNA            complement(12317..12389)
                     /locus_tag="ACG930_002400"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12354..12356),aa:Thr,seq:tgt)
     gene            complement(12407..12488)
                     /locus_tag="ACG930_002401"
     tRNA            complement(12407..12488)
                     /locus_tag="ACG930_002401"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12452..12454),aa:Leu,seq:tag)
     gene            complement(12496..12568)
                     /locus_tag="ACG930_002402"
     tRNA            complement(12496..12568)
                     /locus_tag="ACG930_002402"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12533..12535),aa:Lys,seq:ttt)
     gene            complement(12572..12644)
                     /locus_tag="ACG930_002403"
     tRNA            complement(12572..12644)
                     /locus_tag="ACG930_002403"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12609..12611),aa:Val,seq:tac)
BASE COUNT         4071 a         2709 c         2235 g         3640 t
ORIGIN      
        1 ttttaaataa acgagagaaa aataatttaa agaaaaaaat gctcattcca tttgattcag
       61 aagtgaaagg attactcaat aaactaacta tttctaatat agactcgact agggaaaaaa
      121 tcataaaaat atttgataaa attaataatt tattcaagaa tgacaatgct gaattaagga
      181 agggtctttt agagtttaaa cttcaagaac tagaacttca ttactcttat ttagtgaaaa
      241 ttaccgaaga aaaagaacaa caaaaagcaa taaaagaaca gatgatagaa gaggaaaaag
      301 ttcgtagaga aattgatcgt gaaaagaaac gtattgataa agaacaacgt caattcaatt
      361 ctgaaatttc caaattaatc gcatatatgc aaaaagctaa tgcagatgtg gaaaaagaat
      421 tatatgcaaa taaaattcaa gaactggaag aaaaattaaa agaattagaa gttatacgtg
      481 aaaatgtatt acaaagagaa ttaaatacta gagccggtta tgtgtatgta attagtaata
      541 ttgggtcttt tggtgaagac atatataaaa ttggtatgac tagaagatta gaacctatgg
      601 atagaataaa agaattgagt agtgcatcgg ttccatttga atttgacgtt catgcgatga
      661 ttttttcaga ggacgctccg tctttggaaa ctaaattgca taatcatttt agaaaacaag
      721 aagttaataa aattaatcaa agaaaagaat ttttcaaagt ttcactagac gaaatagaga
      781 aagttgtttt agaaaattat aatggaacag taacatttac aaaattagct aaagctgaac
      841 aatatagacg atctttagaa ttgtcaaaag attaaatata taaaaagcct tcgggctttt
      901 tcttttaaca attaatagga acgtatattc gaaaggaata gaaataatgt ggttagaaaa
      961 aataaatgac aaaaaattta agtacaccga acgttatacg gatcccttaa ctgaaaaaaa
     1021 gagaaaagtg tccgttactt tatctagcaa ttcacgccaa gcttggaatc aagctaactt
     1081 acttttgaat gaaaaaatcg cagaaaaaat aaaacgaaat gaagaattac cactaacttt
     1141 tggagaatta aaaactaaat gggatgaaaa atacaagcca actgtaaaag aaagttccta
     1201 tcgaacaact caggtttatc tatcattaat ttcaaaatat ataaaagatg atgtacttgt
     1261 aaaaaacgtt aatagtaatc ttatacaaga tatgctagat tactactatt ttgaaaaaaa
     1321 tttatcatat aattatgtaa tacatttaaa aacttttaca ggaatgattt ttaaattcgc
     1381 caaccgtcga tatggattaa aatataatcc cgtaaatggg gtttctttag caagaaaacc
     1441 taagacaaac gaagaaataa aaaaagaaaa agatggttat ttatcaaaag aagaagttca
     1501 aatgattgct agtaaacaaa aaagttcaca tcaacagtca cgttattctt taattactaa
     1561 atttttgttt ttaactggac tacgttatgg tgaattgata tctttgactg aatctgatta
     1621 tgatggtaat aaaattacgg tttctggtac ttatgattac gagttaaaaa ttaaaacaac
     1681 aactaaaaat acaggttctt atagaaccat tgaattatca agtaatgcta aagaaatcat
     1741 agatcaatta attgaagaaa acaaattaat taagaataat aaagataaat acattttcat
     1801 ctctaaaaat ggtaacccga tatctattca agcatataat caatctttaa gagcagtatc
     1861 caaagaatta aacctagata aaaaagtttc ttctcacatg ttaaggcatt cccacatttc
     1921 tctacttaca gaattaggaa tcccattaaa agccattatg gatcgtgtag gacatgaaga
     1981 ttcaaaaaca acattaaaga tttatactca tacaactaaa aatatgcaaa atcaactagt
     2041 agaaaaacta ggaaaaatag aaatttaaat tgcccctttt ctgcccctta taaaaacaaa
     2101 caacataaaa tatataaaaa gaaccccgtt ataacgaggt tcttttaatt taactttcaa
     2161 atacaaattg attatgataa agttccgcat aaaatccatt ttctgctaat aactcatgat
     2221 gactgccttc ttcaatgact tccccatcac gcaagacaac gattctatct gcattcaaga
     2281 ttgttttcag ccggtgagca atcacaaagc tggttcttcc tttgattgct tcatccattg
     2341 ctttttggat ccttgcttct gttaccgtgt ctacattact tgttgcttca tccaaaatca
     2401 ataaagatgg atttgtgatg atcgttcgag caatactgat caactgcttt tgacctgtac
     2461 tgaataagtt attttcttcg gatatctctg tatcataacc tttttctaac gtcatgatga
     2521 agtcatgaat attcgcttgt tttgctgcat tgatgacttc ttcatctgaa gcgtccggtt
     2581 tgccgaatgt gatattgtct ttgatcgttc cggagaacaa tacagattct tgcaaaacga
     2641 ttcctacatg tctacgtaat gcatcaagat cataatctcg gatatctatt ccatcgatga
     2701 ctactgaacc atcattgaca tcgtaaaaac ggtttagcag attcatgatc gtcgttttcc
     2761 ccgatcctgt tggaccaaca agagcaacca tttctccttt gtccacattg atcgagacat
     2821 ctttcaagac tagtttttct ggagaataac caaaatctac gtgctgcaac gcaagacctt
     2881 tttcaacacc atcaaatgct ttaccgtttt ctggtttgac ttcatctttt tcatcaaata
     2941 tttcattcaa tcgtcttgcc cctgtaatcg ctaattggat catgctgtat ccagatgaaa
     3001 tctgcatcag tggttggtaa tattgttgtg aatactggac gaatgtcaca actaagccta
     3061 atgccaccga acgttccaaa tcaccattta atgctaacca gccgccgaaa aagataacta
     3121 tcgctgtatt gaccagtgac attccttgca tcatcggaaa tagtagacca gaataagctt
     3181 gtcctttgaa ggttgcttcg cgaacacttt gattatgctc taagaatcct tcaatcgttt
     3241 cttcttgtaa gccatttgtg atgatgacac gttgtccgct gattttttca tccatataac
     3301 catttagttt ccccacttca tcttgctgaa gatccacata tttccgtgct ttgcggataa
     3361 tcaagacagc tatcaaaacg gctactggag tggaagcaat tgtagcccaa gctaactcta
     3421 cattttggcg gaacatcatg atcaagatcc cgacaagtaa aacagcattc gtgatgactt
     3481 gaagcaaagc ttggttcaaa ctattttgaa tattatctaa gtcactggta aaacgactta
     3541 aaatttcacc gtcttgatga gaatcaaaga aacggatcgt caatttttcc aatttgttga
     3601 atagaccgat acgcattcgg ttcgttgact tccctactac ttgtgtgaac aaaatactat
     3661 agataaagtt ggctgcacta gctagtacat aaaacagcaa gagtttccat attacagaaa
     3721 caaatttgct tttatcgtct acgccttgca tcaagcctcc tacgtaatta gctaattctt
     3781 gaaaagcttc cccgatgtat tgaggtgcct ttacttgtag ataggtagca atgatcactg
     3841 tgataaagat aaagaaaaag gagagtttgt accgcttcaa atagtgatag aaaaatttac
     3901 ttgcttttat tagatcagtc atacttactc ctccgttcct ttttgagttt caaagatttc
     3961 ctgatagaca cggtttccag ctaccaattc ctcatgggtt ccttcgccga ctaatctgcc
     4021 ttcatccaat actaagatgc ggtctgcttt gacaacagaa gcaatttttt gtgcgatgac
     4081 aatcgtcgtt gttcccttca aatctcgatc gagtgcttct cggaccagct tttcagagcg
     4141 agcatccagt gcactcgtac tgtcatctag gatcaagatc tttggattac cgataacgcc
     4201 acgagtaatg gataaacgtt gcttttgacc accagaaaag ttactgctac gttcttctat
     4261 tggtgcttcg taacgatcag ataacttttc gatgaattct tttgcttgag caatagaaga
     4321 agcatgttcc atctcttttt ctgttgcatt ctttttccct tggcgcaagt tttgagcaat
     4381 cgttcctgag aataaaattg ctttttgcaa aacaaaggaa accgtttgtc ttaaactctt
     4441 ttcatttact tgacgaagat ctacaccacc tacttcaact ttgccttctg tcggatcaaa
     4501 tagacgaggg atcaattgtg ctagtgttga cttcccggca ccagtcgccc cgacgatacc
     4561 aaccatttct ccaggtttga tagaaaagct gatatcttta agcgtatctg tatcctcacc
     4621 aggataacga aaagaaacat ggtcaaaagt gacagaaccc gtcaactctt gttctggaac
     4681 gtctaaataa gtaagatctg gttcagcatc taaaatttcc gcaatccgct tcagcgatac
     4741 ggctgctctt gaagtcatca tcatcatcat tccgccaata atgattgcca tcataatctg
     4801 catcaagtag ttcatgaatg aagcaattcc accaattaac gtaggatcat ctttaacaag
     4861 atcgctcaca aaaaagatcg ccccaaccac agccaaattg gcagccagca tgaaggacgg
     4921 gatcatcaca gaaaataatg taccgactat gatgttgtgt tttgttaagt cctcacttac
     4981 tttgctgaat gacttcaatt ggttttcttc ttgtacaaaa gatttcacta cacgaatccc
     5041 tagtaagttt tcttttgcaa tgctattcac acgatcaatc agtttttgaa tgatcatgaa
     5101 gtgcttgccc atccttgtaa atgaaagtgc cgtaatcaga aataccgtaa cgataagcgc
     5161 tacgatgatc caccataatt gcggcatcgt gatcatagct aaaatgaagg caccaataaa
     5221 taagaatgga attcgaaaaa gtgattgcaa agaaatcatc actaaatttt ggatttgcgt
     5281 gatatcattt gttagacgaa caacaagatt tccagcagag aactgttcga tatttccaaa
     5341 tgaaaatgtc tggatctttc gaaatgcttc ttctcggata tctgcactta cgccttgagc
     5401 tacttttgca gagaaaatcg tgttcgttac acctgcggct aatcctagca aagccagact
     5461 gatcaggtaa ataccaattg ttttcatttc atcattatct tctgtaataa tagcttccaa
     5521 tacttgctgt agtaacttag gttgccataa tgctgctgca accatgactg ctacggacag
     5581 caaggaaata aaaacagata ctttatattt tttcgcatgt cgtaagatta atttcattcg
     5641 ttgattacac ccctttgttt aaattgacag gactaattta acactgtaaa attagaccga
     5701 ctaacaattt accatgttta aaaagataat gcaatacacg aggttgataa aatggaaata
     5761 aagctttctc aagcaatcat cattcaggcc gcctttgata tcctggctga aacacaagct
     5821 ctttcgcagc tttccatgcg aaacatcgca aacagaattc atgttcaagc acctgcttta
     5881 tattggtatt tcaaaaacaa acaacagctc ttgcaaaaaa tggctgaaac aatggaagaa
     5941 gaattagcgc ttccagatcc aactttgcct tggaatgaac agttgctgca gtatatggaa
     6001 aattactatg acctttatac acgtttccct tgtggggcag aattagaaat caatactgtg
     6061 cccgcttttc cgagtcgatt agaacatttg gagcaaatga tccaattact tgttcgtgaa
     6121 ggattttcag tcacccaaag tcatcaggcc attgcctctc tccacaattt attgattgga
     6181 cagttaatgg atcagcagca tgaacagcag cttcgacaaa aaattatgga cggaaatgaa
     6241 tttttgaaag aaacagttct atttatgcgt aattatgtag ttgaaaatca attagaggga
     6301 tttaaagaaa gtatgcagtc ccatgcagaa ttgaatgaaa aagcactctt tctaacgagt
     6361 gcacaaacct atattgaagg cttatgccaa caaaataaaa gaagagaaaa cgagcagtaa
     6421 aaaagctcct atagagatca ctatgtttgt gatctctata ggagctatct ttttaagact
     6481 ctttttttat ttttcttcca ttagccacgc caatgcacgt tgaatccatt ggtcccagaa
     6541 gatccagtta tgatcgccag gtccttgttc aaaggtgacc gccaagcctt gttcctgcat
     6601 agcagatacc atttcctgat ttgcctgata aagaaaatca gattccccac aagccatata
     6661 aaatcttgga actggttttc cgctttttac tagttctttc aataagtatt gcggatcatt
     6721 ttttgaacct tcgatttgat ccaatggtcc aaagatccct tcccaaaaag atgctttacg
     6781 aaccatcaaa agatcatcca ttcgatttcc tacagaaaca gcgcctgaaa gagagattac
     6841 tgctgcgaaa ttttctgatt ttgcaaggcc tagttttaac gcgccatatc cgcccatcga
     6901 taatccagcg gcatatgttt tttctctttt tcttgttaat tgcgggaata attcatgaca
     6961 aatctcaggt agctcttctg caatgaatgt ccaatacttc atgtcataaa ctgtatctgt
     7021 gtaccagcca agatcagtag atggcatgat gacagctaat ccgtagtttg ctacataacg
     7081 ttcaatcgac gtacgtcttt cccatacact atgattgcca cccattccat gaagtaaata
     7141 taaaacaggt atatccgttg tctcttgctc tgaactggtg ccaatcacct tttttgttgt
     7201 ttgcggtagt atcacattta gattgacttc catttctaac acattcgaat aaatatttgc
     7261 ttgaataaat gccatatttt cgccttcctt agtaagaagt tatttttgaa taactttaaa
     7321 tttgaatgat tcggctacgt acatatctta accgaaacta ctgttttatt ttaccacttt
     7381 tttcatgaac gaaaagcgtt aagaccaaag caatgatcac gagtaacaag ccaactagat
     7441 aaacggaatg taacccatca taaagaattt ttcttaatgg taacaaaata tccgcatcaa
     7501 tatatttagc cgtttgtgga ttcaccagtt tattcatgat atctgcatca tttgttaaat
     7561 ttgctgctgc aagttctcgt ttagttaccc catttatcaa taaaccaaaa atagaaacca
     7621 tgactgtttg accaattgtt cgaactaacg tattaaaaga agttgctaca ccaagctggt
     7681 cacgagatac actattttgt gcactgacag tcgaggtagt catggtcaca cctaagccta
     7741 taccgatgac cgttgatata gcaaaaaacc ataaatagtt acttctgaaa ggcataagat
     7801 acaaccaagc gcccccaata gctgcgatta gtagtccaat tctcaagacc caatgagttt
     7861 tcatttgagt catccacttg cttgcaagga aagaaccgac catccagact agtgataatg
     7921 gtgctaatac cagcccacca attgctgcat tcagccctaa tacaccttgc atccacatag
     7981 ggatataaac atcgattccc atcaaaaaac cactagccaa tgctgcagcc aagttgacca
     8041 caacaaatag tggatttttg aataaatgca tcatgatgac aggatcttta gctctttttt
     8101 cggcaaaaac aaaaatacct aacattacga tactacctag cagcaaagca gaaacaagcg
     8161 gactcattcc ttcgtctcct aataattgga accctaacag caatgagaca agcatggcca
     8221 tcaaactaaa actaccaaaa atatccattg gtttagactc atgtatgatt tttggttcat
     8281 ttaaatatag ccaaatcaaa ataattaata gaattccgat cggcacattg ataaaaaaga
     8341 tccagtgcca gctgatcgtt tcaacgatga atcctcccgc aagcggtcca aaaacactgg
     8401 caatccccca ggctgaacta ttcaaaccta aaacttttgc tcgcttttca atagaataaa
     8461 gatcgccgat gatcgtcaaa gctactggca tcattgcccc agcacccatc ccttgaatcg
     8521 cacgagcagc aatcaaccca atcatgcttt gagataaacc gcaaaataac gaaccgataa
     8581 taaacaataa tgtcccaaaa ataaagattg gtttccgtcc cactttatcc gcaagttttc
     8641 cgtaaatcgg agtaagcata gcgtttgtca gcaaataaat cgaaaatacc cagttcatga
     8701 tttccattcc atgtaatgaa ccgacaatcg ttggcatagc ggttgttacg attgtacctt
     8761 caatagccgt catgaacgtt gcaatgaaaa tactcactgt gaccaaagta acatttgttt
     8821 cttttttcat cttattcctc cctttcatta tgacaggatc taaaaataga taaataatta
     8881 ctatcttttt caagaggtta actgccataa aaaaagctgg aacaaccacc acttggcgat
     8941 cgttccagct gaatataact tattttgcta aacttgcttt caacgcatct actttgtccg
     9001 tatgttccca aggcaaatct acatctgtac gaccaaaatg accgtaagca gctgtttgtt
     9061 tgtaaatcgg acgacgcaaa tcaagcatct cgatgattcc tgctggccga agatcgaagt
     9121 tttctctcac tgcagcaatc agttcttctt ccggaaccgt tccagtaccg aaagtattga
     9181 ttgagatcga aacaggttga gcaacaccaa tcgcataagc tagctgtact tctgctttgc
     9241 gagcaagccc tgctgcaaca atgtttttag caatataacg tgcagcatag ctggcagaac
     9301 ggtcaacttt tgtcgcatct ttaccagaaa aagcaccgcc accatgacga gcataaccgc
     9361 catacgtatc aacaatgatt tttcttcctg ttaatccggc atccccttga ggaccaccaa
     9421 tgacaaatcg gccagtcgga ttgatataat atttcgtttg atcatctaat aattcagctg
     9481 gaataacttc cttcactact ttttcgatga catcatgacg aattgtttca ttatctactg
     9541 catcatcatg ctgtgttgaa ataacgattg tatctacgcg ttccggttgt ccttgatcat
     9601 catattcaac cgttacttga gattttgcat ctggacgtaa atacgttaat tcatttgatt
     9661 tacgcaaatc tgccaagcgt cgtaccagac gatgactcaa agcgattggt aaaggcatca
     9721 attctggtgt ttcatctaca gcaaacccaa acattaaacc ttggtcacca gcaccaatct
     9781 catctaatac gtctttttta tcttcatccc ggatctcaag tgcttcatca actccttgag
     9841 caatatcagg agattgttca tcaatcgcaa ccaatacagc tgctgtatct ccatcaaatc
     9901 cgaattttgc acgtgtataa ccaatttctt ttattgtttc ccgtacgact ttttgaatat
     9961 ctacatatgc cgtcgtagat atttctccaa atactaaaac aagaccagtt gttacagacg
    10021 tttcacacgc tactcgtgct gttggatctt gttttaaaat tgcatccaag attgcatcac
    10081 tgatttggtc agcaatttta tctggatgtc cttcagaaac agattctgat gtaaataagt
    10141 gtctttctac cattataatg attcccccta gttaaattcg gttacaaggc atctccgtcc
    10201 tgcggatcct ttcgggaact tgcaacgaac caagtatagc agataaaaca gttttctgct
    10261 cgtatttttt catttttttg cttaaaaaat ataaaaatat tttacattag aactgtccaa
    10321 aaaagcttag cacaatcatc cataaagata actctgctaa gctttttaaa atcattcttt
    10381 cagataaaaa gaaaaagata ctcaaaaagt atcttccatg acccgtacgg gattcgaacc
    10441 cgtgttaccg ccgtgaaagg gcggtgtctt aaccgcttga ccaacgggcc aataaaataa
    10501 atgggcctaa atggactcga accatcgacc tcacgcttat caggcgtgcg ctctaaccag
    10561 ctgagctata ggcccataaa aactaaaagc gggtgacgag aatcgaactc gcgacaacag
    10621 cttggaaggc tgtggtttta ccactaaact acacccgcat aatggcgcgg gacagaatcg
    10681 aactgccgac acatggagct tcaatccatt gctctaccaa ctgagctacc gagccaaacg
    10741 gttccgacgg gaatcgaacc cgcgatctcc tgcgtgacag gcaggcatgt taacccctac
    10801 accacggaac caatgttttt agtttttaat tgcgggagca ggatttgaac ctacgacctt
    10861 cgggttatga gcccgacgag ctaccagact gctccatccc gcgataatat gaaaaaggag
    10921 gataagggat tcgaaccctt gcacggtttt acccgcctga cggttttcaa gaccgttccc
    10981 ttcagccgga cttgggtaat cctccatgta aaactatatt aaattaatga cccgtacggg
    11041 attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta accgcttgac caacgggcca
    11101 ggtaaaacaa aatattgaaa cggagaagga gggatttgaa ccctcgcgcc ggtttcccga
    11161 cctacaccct tagcaggggc gcctcttcag ccacttgagt acttccccaa aaccaataag
    11221 attttgtact aatgggccta aatggactcg aaccatcgac ctcacgctta tcaggcgtgc
    11281 gctctaacca gctgagctat aggcccataa aaaactaaaa gcgggtgacg agaatcgaac
    11341 tcgcgacaac agcttggaag gctgtggttt taccactaaa ctacacccgc atggcggttc
    11401 cgacgggaat cgaacccgcg atctcctgcg tgacaggcag gcatgttaac ccctacacca
    11461 cggaaccagt gtttttagtt tttaattgcg ggagcaggat ttgaacctac gaccttcggg
    11521 ttatgagccc gacgagctac cagactgctc catcccgcga taatatgaaa aaggaggata
    11581 agggattcga acccttgcac ggttttaccc gcctgacggt tttcaagacc gttcccttca
    11641 gccggacttg ggtaatcctc catatgaaac ttacaacgcc acaatggacc ttgtaggact
    11701 cgaacctacg accggacggt tatgagccgt ctgctctaac caactgagct aaaggtccag
    11761 gctcttaaaa atcgcggcgg aggggatcga acccccgacc tcccgggtat gaaccggacg
    11821 ctctagccag ctgagctaca ccgcgaaaaa gatattcatt atttaaatga aatggagcct
    11881 agcgggatcg aaccgctgac ctcctgcgtg caaagcaggc gctctcccag ctgagctaag
    11941 gccccgtgtt taaatttata attatcggga agacaggatt cgaacctgcg accccttggt
    12001 cccaaaccaa gtgctctacc aagctgagct acttcccgtt taattaacgc gcccaagagg
    12061 agtcgaaccc ctaacctttt gatccgtagt caaacactct atccagttga gctatgggcg
    12121 catatttgaa atgccgagga ccggaatcga accggtacgg tgatcactca ccgcaggatt
    12181 ttaagtcctg tgcgtctgcc agttccgcca ccccggcgcg attgctttgg caaagcggaa
    12241 aacggggttc gaacccgcga cccccacctt ggcaaggtgg tgctctacca ctgagctatt
    12301 tccgcgtgtt taaagatgcc ggctaaagga cttgaaccct cgaccctctg attacaaatc
    12361 agatgctcta ccaactgagc taagccggca tgtaaaactt aaattatgcg ggtgaaggga
    12421 cttgaacccc cacgccgtaa ggcgctagat cctaaatcta gtgcgtctgc caattccgcc
    12481 acacccgcaa aaatatgagc cgtacagggc tcgaacctgt gaccctctga ttaaaagtca
    12541 gatgctctac caactgagct aacggctcat atggaggtta acgggatcga accgctgacc
    12601 ctctgcttgt aaggcagatg ctctcccagc tgagctaaac ctccatggat aactt
//
LOCUS       DAZKPE010000077        12418 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000077 DAZKPE010000000
VERSION     DAZKPE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.077"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="ACG930_002404"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="ACG930_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFQ0519529.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /gene="pyrH"
                     /locus_tag="ACG930_002405"
     CDS             complement(738..1460)
                     /gene="pyrH"
                     /locus_tag="ACG930_002405"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFQ0519530.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /gene="tsf"
                     /locus_tag="ACG930_002406"
     CDS             complement(1596..2477)
                     /gene="tsf"
                     /locus_tag="ACG930_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFQ0519531.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="ACG930_002407"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="ACG930_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFQ0519532.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="ACG930_002408"
     CDS             3717..4196
                     /locus_tag="ACG930_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFQ0519533.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="ACG930_002409"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="ACG930_002409"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFQ0519534.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="ACG930_002410"
     CDS             5497..5625
                     /locus_tag="ACG930_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFQ0519535.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5629..6174
                     /locus_tag="ACG930_002411"
     CDS             5629..6174
                     /locus_tag="ACG930_002411"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFQ0519536.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6627..8318)
                     /gene="argS"
                     /locus_tag="ACG930_002412"
     CDS             complement(6627..8318)
                     /gene="argS"
                     /locus_tag="ACG930_002412"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFQ0519537.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8738..9685)
                     /gene="arcC"
                     /locus_tag="ACG930_002413"
     CDS             complement(8738..9685)
                     /gene="arcC"
                     /locus_tag="ACG930_002413"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFQ0519538.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9800..10819)
                     /gene="argF"
                     /locus_tag="ACG930_002414"
     CDS             complement(9800..10819)
                     /gene="argF"
                     /locus_tag="ACG930_002414"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFQ0519539.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10910..12139)
                     /gene="arcA"
                     /locus_tag="ACG930_002415"
     CDS             complement(10910..12139)
                     /gene="arcA"
                     /locus_tag="ACG930_002415"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFQ0519540.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3418 a         2549 c         2221 g         4230 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaatcca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaag ggagctgtga cacgactttt gtcacagtcc ccttatttgc aaacaaacag
     6481 tgtttaagag acaacctctc cactaaacgg tgttcattca gctgactctc ggtatttgct
     6541 caaaaaacga taaaatttga aaagctattt tctcttttgt ttctctaata ctcggatcag
     6601 aacgctgatt tcacattctc tttttcttac atcttatctg gtgcatgaag tcctagcaaa
     6661 cgaaggtctt ctttcaataa tacagtcact gcataaacta gagctaagcg tgcttctttt
     6721 tgttcatcat cagctaaaat cttcgtatga gcatagtatt tgttgaatgc ttgtgctaat
     6781 ttgattgcat gtttcgcaat cactgacggt tcgtattttt ccccagcaga caagaccgtt
     6841 tcagggtatt tttgaactaa tttaaccact tcccagctgg tatcgtcatt caatgcatag
     6901 tctgctgttt ctgaagggac aaatcctgct ttttccaaca ggctgactgc acgagcatgt
     6961 gtatattgca cataaggtcc agtttctcct tcaaatcgaa caacttcttc caggttaaag
     7021 tcaaatgtat tcagtcgatc gtttttcaaa tcgtggaaaa tgactgcccc aaccccaact
     7081 tgtttagcta cagcatcttt gttttccaaa tcagggtttt tctcgctgat ttgttcttta
     7141 gcagattgga ttgcttcatt taatacttct tctaataaga cgatctttcc tttacgagtt
     7201 gataattttt taccaccttg cgtgatcaaa ccaaatggaa tatggtgcat gtcgtcagac
     7261 cagtcaaagc ccatttcctt caagacagct ttcaactgtt taaaatgata gctttgttca
     7321 ttccctacta catatagaga ttgtttgaag tcgtaagtac gtttacggta caatgcagca
     7381 gctaagtcac gtgtaatgta tagtgtcgca ccgtctgact tcttaatcaa cgctggattc
     7441 aggtcataag cagataggtc aacgatctct gcacctttat cctcgttcag caaatgtttt
     7501 tcttctaaaa gtttgacgat ttcatccatc ttgtcattgt agaaagcttc accgttcaac
     7561 gaatcgaaac gtacttccag cagatcatag attttattga attctttcat cgattcatca
     7621 cggaaccatt gccataattg aatagcctct ttatcgcctt cttccagacg tttgaaccaa
     7681 gcacgagctt cttcatttaa ttctggttct gtttcagcta cttcatggaa ttggacgtat
     7741 aaacgaagca attcattgat tggttctgct ttaacagctt cttctgtacc ccattttttg
     7801 taagcgacga tcagttttcc aaactgtgtt ccccagtcac ctaaatggtt gatgcggatt
     7861 ggctgataac cgattttttc cataatgaaa ccgatcgaat taccgataac tgtcgaacgc
     7921 aaatgtccca ttgagattgg tttggcaata ttaggagaag acatgtcgat tggtactgtt
     7981 ccttgattcc cgatgttgct atccccataa tgttcttttt ctttcactac ggtttgcaaa
     8041 acttttttgc tgataagttc tttattcatg aaaaagttca agtaaggtcc gacaacttcg
     8101 attttttcaa agttggcaga atcgattttt tctgctaaat ctgcagcgat ttgctgtggc
     8161 gcttttcggt aaacttttgc taatgaaaag gctggaaatg caacatctcc gtgttcagct
     8221 gattttggat tttctagtaa ttgctcgact tgttccagtg ttaaatcatc tttgacagcg
     8281 tcatagacag cttttgcgac aagatcttta ttattcatct ttattcctcc taaagtgttc
     8341 ccttgattgt taaacaaaaa aaatctctag cgacggcata cttagtatgc catcactaga
     8401 gacgagattt cccgcggtac cactccaatt gtcctaaaaa aggaccagct ccatctgata
     8461 tcggtagacg accgtctgtt taaaacagaa ttctccaagt gcgcttcgtt gtatcttctt
     8521 cattcggctt ccaccacttc cgaattcgct agccaagaat gatacaagta ctctcttgtt
     8581 caacaaatct tagtcttatt aaactttctt gaattatatc agaaaaaaaa acgaaaggct
     8641 agtcgtttca taaaaaaaaa atccagatgg cctaaaggag aagaaatacc acctggatag
     8701 ctataaatca tttcgtaaat acgaaagact taacaaatta atcagctacg ataatcgttc
     8761 cttcttcaga agctaaaaga ttctcgatat tttctaaaga agtgatgatt gccttagcgt
     8821 ttggttttgc ttcaacaaat gcaatagctg cttctacttt cggaagcatg cttcctggag
     8881 cgaattgctt ttcatcaatg tattgtttca tttctgaaac agtaacagtt tctaatttct
     8941 tttgatctgg tttttggtaa ttgacataca cattgtctac tcctgtcaat acgatcagca
     9001 aatccgcatc gatgatttcg gctaattttt ctgaagcaaa atctttatcg attacggctt
     9061 ctcgtccttc taatccagta gctgtttcta caacaggaat cccaccgcca ccaacagaga
     9121 ctgtgataac tccttgatcg accagcgttt cgatgacacg tgcttcttta atcgagatgg
     9181 gtttagggga agcgactact tttctccatc cacgtccagc atcttctttg aatgtcacag
     9241 tggagtcagc attcatttgt tctttggctt cttcttccgt gtagaatgga ccgactggtt
     9301 tacttggatt tttgaatgaa ggatcatttt catccacaat aacttgagtg actaaagaaa
     9361 ccacatcttt atcgatccct ttttccttca gtacttcgcc catggcgttt tgtaaccagt
     9421 aaccgataga tccttctgtc attgcaacac atgtatctaa aggcattgcc ggtgttttct
     9481 cagaatcagc agcttgctgc tgaatcaata ggttaccgac ttgcggacca tttccgtggg
     9541 agatgatcaa ttcatctcct tgttcgataa atttcactaa atactttgct gtttccatta
     9601 acgcttcttg ttgggctttt gcacttgcat ccgtagacaa gatggcattg ccccctaaag
     9661 cgacaactac ttttcgtttg gccatttcat tcgtcctttc ttcagttcta ccgaattttc
     9721 tagataacaa aacgagccag cgttttgtga ttttccctca atgctgactc gttttttcgt
     9781 gagatgaatg tggttatgct taaacgcgag ggataaacaa gttacctaat gttgctgcca
     9841 tgatcgcttt gattgagtgc atacgatttt ctgcttggtc aaattgacga gcatatttgc
     9901 tgcggaagac ttcatctgtt acttccattt cagtgatgcc aaagcgttct ttcatttgtt
     9961 caccgtaaac agtgtttgta tcatggaaag ctggcaagca gtgcaagaag atcaaacgat
    10021 ctgtgttgtg tgttttttct accatttcca tattgatttg gtaaggtttc aacaatttga
    10081 tacgttcttc gaatttatct tcttcaccca ttgataccca tacatcagaa taaaggacgt
    10141 ctgctccgtc tacaccttta tcaacatcgt cggtaatcat caattgtgca ccggattttt
    10201 cagcaaagcc ttctgccatt ttgacgattt cttcttcagg ttgtaattct tttggtgcaa
    10261 cgatacgcat attcgctcct aaaattgcac ctgtgactaa taaagagtta gccatattgt
    10321 ttcgaccatc tccgcagtaa gcaacagtga taccttctac tgttccaaag ttttcttgga
    10381 tagttaaaaa gtcagcgatc atttgtgttg gatgccattc atcagtcaag ccattccaaa
    10441 ctggaacacc agagaattct gctagttcct ctaccatttt ttgactgaat ccacggaatt
    10501 cgattccgtc aaacatacgt cctagtactt tagctgtatc ttctgtggat tcttttttac
    10561 ctaattggat atcatttgca cctagatatt caggatgtgc acctagatcg atcgctgcag
    10621 tagtaaatgc agaacgagta cgtgtagatg ttttttcaaa taaaagcgca atattttttc
    10681 cttctagata gtgatgtggg ataccacgtt ttttcaagtc tttcaagtgt tctgaaaaat
    10741 cgatcaaata ttgtaattct tcttttgtaa agtctttttc tgctaataag cttcttcctt
    10801 ggaatactga ttctttcata ttaaacattc tcctttagat tgtttttatt taagattaaa
    10861 gaggaaatcc cgacggcagc tgacagtaag actgccgtca ggaaacaaat tacttcaagt
    10921 cttcacggac aagtggttgg ctcatgcagc gtggaccacc acgacctcgt gacaattcac
    10981 ttgaattgat ttctaacact ttgatgccat agctacgaag caattcgttc gatacataat
    11041 ttcggttata agtgactaca acacctggag cgattgccaa tgtgtttgat ccatcattcc
    11101 attgttctcg aggtgcaacg atctcatctc cattaccagt tgggatcagt acaagatcat
    11161 ctaatccaag agcagctttc atcgtttcgt gtaagttatc tgaatgagta atcttgatat
    11221 catcaccatc tggttcgatt gtaaagacat ccatcttacc gtctttactt tgaattgctg
    11281 gatggatagt gaatttatcg tgatctacca ttgtaaatac ggtatccaaa tgcatcattg
    11341 cacggttgtt cggaattttg attgccaaca ctttttcaaa tcctgaattt tttgcgaata
    11401 ggtggcgtgc taatttttct aaagctttcg cattagttcg ttgagaaatc ccaacagcta
    11461 ctactttatc gcttaagatc aattcgtctc cgccttcgat atgatctgga ttttcacgat
    11521 ccaaccatac ttcgattcct ttatttgcaa atcttggatg atgtttcaaa atatattctg
    11581 taaacatcga ttcacgacga cgtgcttcaa aagtcatctt attgactgtc atcccatttc
    11641 ccattgatgc ggaagggtcg cgtgtaaagt acaagtttgg cattgggtcc atgtaaaatg
    11701 gatagtcatc gtctgctgac agatcatata gactgctaga acgtacttcg atatcttttg
    11761 tacgaacccc agccatgatt ttatctacca tttcttgcgt ttccattgat agaaggaact
    11821 catgaagacc ctctcttaca gcattcgatg caatatgaga ttcatccaac attttattca
    11881 agaattgttc tttgacattg cctgcgtcaa tcgcttctgc cgctaatttt tccaagtaaa
    11941 gagtctcgac gccttcattt tgcaatgtct tcgcaaagtt gtcatgttct tcttgagcaa
    12001 tcggaagata tggaatatca tcgaacaaca gacgatccat aatatctggt gtcaaatttt
    12061 ccacttcttg tccaggccgt ttcagtaaaa ctgtctttaa tttccctatt tcagagaaaa
    12121 cgtgaatagg tttatccatg ttgtgttgcc tccttctttt tgattacatg tataggatat
    12181 cctccttttg taatcacttt cataattttg tctcattcaa aatgagacat tcctcacatt
    12241 aatattcgat aattaaataa ttaaacgttt ttctattttt aagcgtaatt tattcatttt
    12301 ttattctgta tacactttca aaaaaatatt tattcattga aaaaattttt ttgaataaat
    12361 taaaaaaata aattatatta tcgttgttag cgtttactat atgtattatt gttgtttt
//
LOCUS       DAZKPE010000078        12274 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000078 DAZKPE010000000
VERSION     DAZKPE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.078"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..186)
                     /locus_tag="ACG930_002416"
     CDS             complement(<1..186)
                     /locus_tag="ACG930_002416"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519541.1"
                     /translation="MPYINKENQGMSKSILFETVSLHSRMIIFIPLKYIKMAGLNGLP
                     LNKGSILFDVGELHQHLF"
     gene            274..891
                     /locus_tag="ACG930_002417"
     CDS             274..891
                     /locus_tag="ACG930_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0519542.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            932..1231
                     /locus_tag="ACG930_002418"
     CDS             932..1231
                     /locus_tag="ACG930_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFQ0519543.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1265..1432
                     /locus_tag="ACG930_002419"
     CDS             1265..1432
                     /locus_tag="ACG930_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFQ0519544.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1477..2082)
                     /locus_tag="ACG930_002420"
     CDS             complement(1477..2082)
                     /locus_tag="ACG930_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0519545.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            2207..5194
                     /locus_tag="ACG930_002421"
     CDS             2207..5194
                     /locus_tag="ACG930_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFQ0519546.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            5361..5750
                     /locus_tag="ACG930_002422"
                     /pseudo
     CDS             5361..5750
                     /locus_tag="ACG930_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            5884..6123
                     /locus_tag="ACG930_002423"
     CDS             5884..6123
                     /locus_tag="ACG930_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFQ0519547.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            6187..6240
                     /locus_tag="ACG930_002424"
     CDS             6187..6240
                     /locus_tag="ACG930_002424"
                     /inference="COORDINATES: protein motif:HMM:NF018061.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFQ0519548.1"
                     /translation="MRNVDKTSTVLKQKSSP"
     gene            complement(6278..7450)
                     /locus_tag="ACG930_002425"
     CDS             complement(6278..7450)
                     /locus_tag="ACG930_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HFQ0519549.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
     gene            7602..8297
                     /gene="vanR-A"
                     /locus_tag="ACG930_002426"
     CDS             7602..8297
                     /gene="vanR-A"
                     /locus_tag="ACG930_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFQ0519550.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            8275..9429
                     /locus_tag="ACG930_002427"
     CDS             8275..9429
                     /locus_tag="ACG930_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFQ0519551.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            9644..10612
                     /locus_tag="ACG930_002428"
     CDS             9644..10612
                     /locus_tag="ACG930_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFQ0519552.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            10605..11636
                     /gene="vanA"
                     /locus_tag="ACG930_002429"
     CDS             10605..11636
                     /gene="vanA"
                     /locus_tag="ACG930_002429"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFQ0519553.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            11642..12250
                     /locus_tag="ACG930_002430"
     CDS             11642..12250
                     /locus_tag="ACG930_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFQ0519554.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         3976 a         2187 c         2508 g         3603 t
ORIGIN      
        1 aaaaagatgt tggtgaagtt caccaacatc aaaaagtata gagcctttat ttaatggcag
       61 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
      121 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
      181 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
      241 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
      301 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
      361 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
      421 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
      481 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
      541 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
      601 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
      661 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
      721 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
      781 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
      841 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
      901 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
      961 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     1021 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     1081 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     1141 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     1201 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     1261 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     1321 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     1381 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     1441 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     1501 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     1561 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     1621 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     1681 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     1741 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     1801 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     1861 tatatcttca taatctcttc ctaaacgatc tagtgatgta acgatgacgc aatcaccttc
     1921 acggatataa tttagtaatt tttgaaactc aggacgctca gtatctttac cactggcttt
     1981 ttcttggaat aatttatcaa tgttaagtcc ttccatcatt gccaattgtc gatccaaatt
     2041 ttgatcttgt gaagatactc gaatatagcc aatttttccc ataaaaaact cctttttaaa
     2101 agtgatataa tttacatgta aaatttactt gtagttttac tgctatcata gcatttttaa
     2161 aaataaattt tatgtagact taaaatttac ttcatggagg gtttaaatgg atgaaatcaa
     2221 aagtaacaaa aaagcatttg gcatttattt aggagaacct agtacagaac aattaaacca
     2281 atttttttat ttgcatgaaa aagatttaga attgatggag actatacgac gaccagctac
     2341 tagattaggt tttgcactac agttagtctc actacgtttt ttaggaactt ttatattaga
     2401 tcttaccaat attccccaaa atgtattgag ttatgtagca actcaactaa atattgatcc
     2461 tggagaaatt atctactata gcaggagaca gaccaggtat cagcacacaa aattgataaa
     2521 atcacattat ggatatcaag atttcaacca accggaaata gaaacatacc tagctaactg
     2581 gcttttaaat agagcgctgt atacaacaga atcttcagat atgttgtttg atatgcttct
     2641 aaaaaaatgt ctggatgaaa agattgtttt acctggaatt actacttttt ctcgttttgt
     2701 tgctagtgca attgaaaaag ctgaagagca tttataccga caattgtctt tggttccaac
     2761 tgaagatgag agaaagcggc ttctcaatca tttagaatta attggaactc cagtttatgg
     2821 ggcaataatc aaaatggaca ttttgagaac cccgttagct gacgatagtc ataaagaaat
     2881 agccagaggt tttgaccgac taaagcaatt tcaagctttc tctactgaaa aatggaagat
     2941 ggaatctatt cctgaaggga aaataaaagt tcttgcaaat tatgcattta aagctaaagc
     3001 tcaattaatt caacgaatga gtgaacagaa aaaactggcg ttgttagtgg catttatttt
     3061 catatacaaa cgtaaggcta tggatgaaca aattttagca ctatctaatt tttttgaaac
     3121 tgtttttaga cgcgccaaaa ataaggaatc taaagaacgt cttcgtacca taaaagatct
     3181 agatcgagcc gcatcgacac tttcagatat tgtagattta gtaatgtcca gtcattctga
     3241 tactaatgaa ctatcccttc gcgatcgtat cttagaaaaa tattctgagg aaaatgttac
     3301 cgaagctgta tcgcaagttc ggctattggt taaaaatgat cgtgaaccaa tagccatttc
     3361 tgaacttctg aacacttatc gaaagttcag aaaatttatt ccggatattt taactacact
     3421 aacatttgac agcaatgact acggtaacaa ctgtaaggaa ctctggacct tcattaataa
     3481 tagatttcct aagccgatta cttacaaaat gtttggagct attaaacata ctcttccaaa
     3541 gaaatggatt tattacattc atgaataccc tgaacaaact aataaatgtg tattgattgc
     3601 agctgtcgaa ttgttaattc aatctttaaa acgccatgat atttatattc ctcagagtgt
     3661 cttatataac aatcctatgg attgcttgat tgatgagaaa acttgggttc aacaaaaata
     3721 cgttttatta gaacaactag atcttccttc ttcagcaaat gaaatgtctt tatggttaaa
     3781 gaacgatttg gaactgtctt ataaagaagc gctaaatcgt tggcctactt ctaaaatggc
     3841 cagaatagaa aatgcagatc gcctggttgt ctctagactt aaaaagacat atgaaaaaaa
     3901 ggaagataag tcttttagac gtcgcattca gcagttactt cctaaaattg atttgtcaga
     3961 tttgttattg gaagtaaacc aacagttaaa tcttactcaa tcatttaacc acttaagtga
     4021 caaggacacc aaaatgaaag acttggatat tagtttatta gcagttcttt tatcagagtc
     4081 ctgcaatatt ggtttttccc cggtttcaaa agaaggattt gattctttaa agtatgatcg
     4141 tcttgtctat gtcaatcatc attatattcg agtggataca ctttcaggag ctaatcaaaa
     4201 aataatacat gcacacagga aacttgccac ctctaagata tggggtgatg ggcatatggc
     4261 ttcagctgac ggtattcgtt atatcacacc acaacgttcc ctatattcta gaagtaatcc
     4321 aaaatatttt ggccgtggtc gtgggatcac attctacaat tttgtctctg atcaatatat
     4381 agggttccac ggaatggtcg tttcagggac actgcgagat tcgctttacc ttctagaagg
     4441 attcctcaat caacccagcg aattaactcc taatcagatc atgactgata cagctggtta
     4501 tagcgatatg atttttggtc tctttggctt attagggttt caatttagtc caagaattgc
     4561 caatgataaa ggaaccaaac tttggcgaat cgacgctaac gctcactacg gggaacttga
     4621 tacgttgtct caaaattcaa ttaatatgga actgatttat acccattggg aggacattct
     4681 tagggttgca ggttcgttga aatctggaaa agtgaatgca acagaattaa cgaaatctct
     4741 tcaacggaat gggcaaccca cgcctttagg aaaagcaata actgagtatg gaaaagttta
     4801 taagacgaaa catcagcttc gttatatttc tgacgaaata tatgcacggc aaattttaga
     4861 acaattgaat aagggggaag ctcggcatgc cttatgccgt aatatttttt atggacgaaa
     4921 aggaaaactc taccagactt attatgatgg gatggaagag cagctcaatg cattaggatt
     4981 agttactaat gccatcatat attggaactc actgtattta gaaaaagtat ttgaacaaat
     5041 gaaagctgaa ggattcgact gttccgaaga aatgatacgc aggcaatctc cactaattag
     5101 tgatcacatc aattttgttg gtaagtatac gtttagatac gaagctgaat tatccaacgg
     5161 taagttacgt ccattgaatg tagaagaatt ctagcaatgt tcgggttttg catgctaccg
     5221 cactatttcg tatgactgtt ccagcgaatc acttcgaata gaaaaagaga aaaacacgag
     5281 aacagcgtta aatcaacgtt tcttgtgttt ttacttttgt gctaccgcac tatttcgttt
     5341 ctatgttcca tgtaccccgt aatcaagaaa actttattaa taatatcaag aaatttatcg
     5401 ttcatttatt ggaaaatgta cctaccgata tagaaaaatt aaatttttct gattatcagg
     5461 aacagaaaga aaaagaagca gaaaaaaata ttgttggcaa atgcccgaaa tgcggaaaca
     5521 atattatact gaaaaaatcg ttttatggtt gttcaaatta tcctgaatgt aagtttactt
     5581 tagctgaaca ttttagaaag aaaaaactaa ccaaaacgaa tgtaaaagaa ttactggagg
     5641 gaaaagaaac cctggtaaaa ggaatcaaaa acaaagagaa aaagctctac aatgccgttg
     5701 taaaaattgg ggaaaaggga tatattgatt ttatatcttt ctcaaaataa acataaaagc
     5761 cctttaaaca gggcttttat atattaatca cttatcacaa atcacaaatc acttatcaca
     5821 aatcacttgt gatttgtgat tgttgatgat aaaataagaa taagaagaaa tagaaagaag
     5881 tgagtgattg tgggaaattt aggcgcacaa aaagaaaaac gaaatgatac accaatcagt
     5941 gcaaaaaaag atataatggg agataagacg gttcgtgttc gtgctgactt gcaccatatc
     6001 ataaaaatcg aaacagcaaa gaatggcgga aacgtaaaag aagttatgga aataagactt
     6061 agaagcaaac ttaagagtgt gttgatagtg cattatctta aaattttgta taataggaat
     6121 tgaagttaaa ttagatgcta aaaatttgta attaagaagg agggattcgt catgttggta
     6181 ttccaaatgc gtaatgtaga taaaacatct actgttttga aacagaagtc aagtccataa
     6241 tcctgtgtaa aatactatac aatgttttac cggtctctca ttgatcaaac ttaatatatt
     6301 ttcttgtaga actgagccat tcgtcatgaa ggtccataag gacagctcca attaatcgat
     6361 tggcagacgt tcggttggga aaaatccgaa taatcttttc tcttctgcgg acttcctggt
     6421 tcagtcgttc aagaaggttg gtgcttttta gccgattatg actatttccg ataaccgtgt
     6481 attgaaaggc atcttcgaag ccattatcca atatttcgca ggcttttgta tatttaggct
     6541 ggtcgatata ttcaccgact aaggcattct tagctgttcg agcgagttca atatccgtaa
     6601 acttaaagat cgcttttact gcttctctaa acggttttga attctttttt ggaatggaac
     6661 tgaagatgtt tcttaaaaaa tggacctggc atctctgcca acttgcgttg gtaaatgact
     6721 tacgaatcgc agacactagg cctttatggg catcagaaat gatgagttct gtccccttta
     6781 ggccgcgttc ttttaagtat tcaaagaaga tggaccatgt gtcatcactt tcttcatttt
     6841 gaatcatgaa gccaatgatt tcacggtcgc caccttctgt tatcccgatc gcaatatggc
     6901 agcttttaga aagcactcga tggtcctcac ggacttttat gtagagaaca tcagtcatca
     6961 gataaggata attcgtacct gagagtgaac ggttctgcca ttcgttgacc atcgggtcta
     7021 actgctcagt caggctagaa acaaaagatt tcgatacaga ttttccacat agctcttcaa
     7081 caatctttga aactttacgt gtcgaaacgc ccgaaacata catctcaagc attgaagcga
     7141 gcagtgcctt ttcatttcgc tgataacgct caaacaccgt cggtgaaaat tcaccatcac
     7201 gtgttctagg cacttttaat tcgagtgtac ccacacgagt cgtaaagtct cgctcataat
     7261 agccatttct ttgactctga cgactttctg aacgttcata gtcatcggct tgaatatatt
     7321 ctgttcgttg attttccatc aattggttga aaacagtggt taaaatattt ttagaaacat
     7381 catcttttac cgaatgttca ataatacttt gaacctcttc gttgttcagt gtaaaatgta
     7441 cttgggtcat gtaacgtcct cctgggtatg tttttgtggt taaaaacatt gtaccgtaaa
     7501 agggctgtta catggccttt tatcttttac acaattatat ggactttatc ctataatctg
     7561 ataaattatt aagggcaaac ttatgtgaaa gggtgataac tatgagcgat aaaatactta
     7621 ttgtggatga tgaacatgaa attgccgatt tggttgaatt atacttaaaa aacgagaatt
     7681 atacggtttt caaatactat accgccaaag aagcattgga atgtatagac aagtctgaga
     7741 ttgaccttgc catattggac atcatgcttc ccggcacaag cggccttact atctgtcaaa
     7801 aaataaggga caagcacacc tatccgatta tcatgctgac cgggaaagat acagaggtag
     7861 ataaaattac agggttaaca atcggcgcgg atgattatat aacgaagccc tttcgcccac
     7921 tggagttaat tgctcgggta aaggcccagt tgcgccgata caaaaaattc agtggagtaa
     7981 aggagcagaa cgaaaatgtt atcgtccact ccggccttgt cattaatgtt aacacccatg
     8041 agtgttatct gaacgagaag cagttatccc ttactcccac cgagttttca atactgcgaa
     8101 tcctctgtga aaacaagggg aatgtggtta gctccgagct gctatttcat gagatatggg
     8161 gcgacgaata tttcagcaag agcaacaaca ccatcaccgt gcatatccgg catttgcgcg
     8221 aaaaaatgaa cgacaccatt gataatccga aatatataaa aacggtatgg ggggttggtt
     8281 ataaaattga aaaataaaaa aaacgactat tccaaactag aacgaaaact ttacatgtat
     8341 atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt atattcgttc aatgatccga
     8401 gggaaacttg gggattggat cttaagtatt ttggaaaaca aatatgactt aaatcacctg
     8461 gacgcgatga aattatatca atattccata cggaacaata tagatatctt tatttatgtg
     8521 gcgattgtca ttagtattct tattctatgt cgcgtcatgc tttcaaaatt cgcaaaatac
     8581 tttgacgaga taaataccgg cattgatgta cttattcaga acgaagataa acaaattgag
     8641 ctttctgcgg aaatggatgt tatggaacaa aagctcaaca cattaaaacg gactctggaa
     8701 aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt tatgtacttg
     8761 gcgcacgata ttaaaacgcc ccttacatcc attatcggtt atttgagcct gcttgacgag
     8821 gctccagaca tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt ggacaaagcg
     8881 tatcgactcg aacagctaat cgacgagttt tttgagatta cacggtataa cctacaaacg
     8941 ataacgctaa caaaaacgca catagaccta tactatatgc tggtgcagat gaccgatgaa
     9001 ttttatcctc agctttccgc acatggaaaa caggcggtta ttcacgcccc cgaggatctg
     9061 accgtgtccg gcgaccctga taaactcgcg agagtcttta acaacatttt gaaaaacgcc
     9121 gctgcataca gtgaggataa cagcatcatt gacattaccg cgggcctctc cggggatgtg
     9181 gtgtcaatcg aattcaagaa cactggaagc atcccaaaag ataagctagc tgccatattt
     9241 gaaaagttct ataggctgga caatgctcgt tcttccgata cgggtggcgc gggacttgga
     9301 ttggcgattg caaaagaaat tattgttcag catggagggc agatttacgc ggaaagcaat
     9361 gataactata cgacgtttag ggtagagctt ccagcgatgc cagacttggt tgataaaagg
     9421 aggtcctaag agatgtatat aattttttag gaaaatctca aggttatctt tactttttct
     9481 taggaaatta acaatttaat attaagaaac ggctcgttct tacacggtag acttaatacc
     9541 gtaagaacga gccgttttcg ttcttcagag aaagatttga caagattacc attggcatcc
     9601 ccgttttatt tggtgccttt cacagaaagg gttggtctta attatgaata acatcggcat
     9661 tactgtttat ggatgtgagc aggatgaggc agatgcattc catgctcttt cgcctcgctt
     9721 tggcgttatg gcaacgataa ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc
     9781 tttcaatcaa tgtatcagtg tgggacataa atcagagatt tccgcctcta ttcttcttgc
     9841 gctgaagaga gccggtgtga aatatatttc tacccgaagc atcggctgca atcatataga
     9901 tacaactgct gctaagagaa tgggcatcac tgtcgacaat gtggcgtact cgccggatag
     9961 cgttgccgat tatactatga tgctaattct tatggcagta cgcaacgtaa aatcgattgt
    10021 gcgctctgtg gaaaaacatg atttcaggtt ggacagcgac cgtggcaagg tactcagcga
    10081 catgacagtt ggtgtggtgg gaacgggcca gataggcaaa gcggttattg agcggctgcg
    10141 aggatttgga tgtaaagtgt tggcttatag tcgcagccga agtatagagg taaactatgt
    10201 accgtttgat gagttgctgc aaaatagcga tatcgttacg cttcatgtgc cgctcaatac
    10261 ggatacgcac tatattatca gccacgaaca aatacagaga atgaagcaag gagcatttct
    10321 tatcaatact gggcgcggtc cacttgtaga tacctatgag ttggttaaag cattagaaaa
    10381 cgggaaactg ggcggtgccg cattggatgt attggaagga gaggaagagt ttttctactc
    10441 tgattgcacc caaaaaccaa ttgataatca atttttactt aaacttcaaa gaatgcctaa
    10501 cgtgataatc acaccgcata cggcctatta taccgagcaa gcgttgcgtg ataccgttga
    10561 aaaaaccatt aaaaactgtt tggattttga aaggagacag gagcatgaat agaataaaag
    10621 ttgcaatact gtttgggggt tgctcagagg agcatgacgt atcggtaaaa tctgcaatag
    10681 agatagccgc taacattaat aaagaaaaat acgagccgtt atacattgga attacgaaat
    10741 ctggtgtatg gaaaatgtgc gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt
    10801 cagctgtact ctcgccggat aaaaaaatgc acggattact tgttaaaaag aaccatgaat
    10861 atgaaatcaa ccatgttgat gtagcatttt cagctttgca tggcaagtca ggtgaagatg
    10921 gatccataca aggtctgttt gaattgtccg gtatcccttt tgtaggctgc gatattcaaa
    10981 gctcagcaat ttgtatggac aaatcgttga catacatcgt tgcgaaaaat gctgggatag
    11041 ctactcccgc cttttgggtt attaataaag atgataggcc ggtggcagct acgtttacct
    11101 atcctgtttt tgttaagccg gcgcgttcag gctcatcctt cggtgtgaaa aaagtcaata
    11161 gcgcggacga attggactac gcaattgaat cggcaagaca atatgacagc aaaatcttaa
    11221 ttgagcaggc tgtttcgggc tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt
    11281 tagttgttgg cgaggtggac caaatcaggc tgcagtacgg aatctttcgt attcatcagg
    11341 aagtcgagcc ggaaaaaggc tctgaaaacg cagttataac cgttcccgca gacctttcag
    11401 cagaggagcg aggacggata caggaaacgg caaaaaaaat atataaagcg ctcggctgta
    11461 gaggtctagc ccgtgtggat atgtttttac aagataacgg ccgcattgta ctgaacgaag
    11521 tcaatactct gcccggtttc acgtcataca gtcgttatcc ccgtatgatg gccgctgcag
    11581 gtattgcact tcccgaactg attgaccgct tgatcgtatt agcgttaaag gggtgataag
    11641 catggaaata ggatttactt ttttagatga aatagtacac ggtgttcgtt gggacgctaa
    11701 atatgccact tgggataatt tcaccggaaa accggttgac ggttatgaag taaatcgcat
    11761 tgtagggaca tacgagttgg ctgaatcgct tttgaaggca aaagaactgg ctgctaccca
    11821 agggtacgga ttgcttctat gggacggtta ccgtcctaag cgtgctgtaa actgttttat
    11881 gcaatgggct gcacagccgg aaaataacct gacaaaggaa agttattatc ccaatattga
    11941 ccgaactgag atgatttcaa aaggatacgt ggcttcaaaa tcaagccata gccgcggcag
    12001 tgccattgat cttacgcttt atcgattaga cacgggtgag cttgtaccaa tggggagccg
    12061 atttgatttt atggatgaac gctctcatca tgcggcaaat ggaatatcat gcaatgaagc
    12121 gcaaaatcgc agacgtttgc gctccatcat ggaaaacagt gggtttgaag catatagcct
    12181 cgaatggtgg cactatgtat taagagacga accatacccc aatagctatt ttgatttccc
    12241 cgttaaataa acttttaacc gttgcacgga caaa
//
LOCUS       DAZKPE010000079        12267 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000079 DAZKPE010000000
VERSION     DAZKPE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.079"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(98..550)
                     /locus_tag="ACG930_002431"
     CDS             complement(98..550)
                     /locus_tag="ACG930_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFQ0519555.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            700..1650
                     /locus_tag="ACG930_002432"
     CDS             700..1650
                     /locus_tag="ACG930_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0519556.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            1643..2602
                     /locus_tag="ACG930_002433"
     CDS             1643..2602
                     /locus_tag="ACG930_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFQ0519557.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            2599..3354
                     /locus_tag="ACG930_002434"
     CDS             2599..3354
                     /locus_tag="ACG930_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519558.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            3377..4330
                     /locus_tag="ACG930_002435"
     CDS             3377..4330
                     /locus_tag="ACG930_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFQ0519559.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(4974..5270)
                     /locus_tag="ACG930_002436"
     CDS             complement(4974..5270)
                     /locus_tag="ACG930_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFQ0519560.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            5625..5981
                     /locus_tag="ACG930_002437"
     CDS             5625..5981
                     /locus_tag="ACG930_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0519561.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            5991..6890
                     /locus_tag="ACG930_002438"
     CDS             5991..6890
                     /locus_tag="ACG930_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0519562.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            7410..8138
                     /locus_tag="ACG930_002439"
     CDS             7410..8138
                     /locus_tag="ACG930_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0519563.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            8283..10310
                     /locus_tag="ACG930_002440"
     CDS             8283..10310
                     /locus_tag="ACG930_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFQ0519564.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            10418..11515
                     /locus_tag="ACG930_002441"
     CDS             10418..11515
                     /locus_tag="ACG930_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFQ0519565.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            11822..>12267
                     /locus_tag="ACG930_002442"
     CDS             11822..>12267
                     /locus_tag="ACG930_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519566.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT         4012 a         2022 c         2467 g         3766 t
ORIGIN      
        1 gtattttaaa agaaaaagct tttgacagat tgtcctattt gatgtcaatc tgatcaaaag
       61 ctttttttgc atgtaaaaat ttatgtgttt tttcgtttta aaataaacga tcccagaagc
      121 tttttttctt ttttggtttt tctttttcag ctggcgaaga gttttcttct gggtattttt
      181 tttcgatatc aatcacaggt tcatttactg cttcttttgc tgttaagagc aatccgaatt
      241 cctcaggatt tgcagtgacg taatcgttga ctacagtgaa acggctattg tttttcgttg
      301 ctagctggat atattggttt tggacagaaa ggggtagagc cccattcaag agtatggaag
      361 catctggatg ttttttgagt tcttttaaaa agttttcttt gttttttggt tggatcattt
      421 cagcaacagt catactaaga tagcagcgtt ccctgaatgt ccctaaatat ttatgctgtt
      481 cttcagggtt cactaaaggt gtaccataaa gtcccttatc caaatggctt tttacatcat
      541 cttgtgccat aaaaaatacc ctccttcttc tctttgtctt tcttacgatt atagcatatt
      601 cccaataata cctaaaacat atgaaaaagc ggttgctttt gttcaacgat tcacttaaaa
      661 taagaatgaa aatcattctc aattagaaag gtggattgga tgcgctacgg acgactagta
      721 gcattattag ttattttaag tagtatttca ttgttcatcg gagtatcgaa tgtacaattg
      781 tcagaactgc tccagttaga tgggcaaagc ttacaaatct tgctagtgac tcgtttgcca
      841 cgaacgattt gtttgatcct tgtgggagcg accagtagta tttgtgggtt gatcatgcaa
      901 catttgaccc aaaataaatt tgtttcacca acgactgcgg gcacgatgga tagtgcgcgt
      961 ttaggtattt tagtggctat gattttccta cctggtgcat ccttgattgt ccgatccttg
     1021 acagcatttt gctttgcttt tgcaggaaca ttgctttttt tatcccttac gcgattgttc
     1081 ctccagaaaa atcaattgat gcttccgttg attggagtca tgttagggaa tatcattggt
     1141 tcagttgcta ctttttttgc ttatcaattc cagttggtac aaaatatgac ttcatggctt
     1201 caagggaatt ttgcgactgt gatacgagga aattatgagt tattgtatgc tgttgttcca
     1261 ttgttgctct tggtttggct atttgcttac cgatttacga tcattggtct gggcgaatcg
     1321 tttgcagtaa atctgggaat agattaccag aagatgcagt ttttaggcat tggcttagta
     1381 tcattggcta gtgcagtcat gttgatcatg gtaggaagca ttccttttat cggagtgatc
     1441 attccgaatc ttgtctctag aatatatgga gatcaagtgc acaaaacaat tggcgtaact
     1501 gctttagcag gtagtttgtt cttagtattt tgcgatcttg tcgctcgcgt gttgattttt
     1561 ccttatgaaa taccagtcag tgtgatcgtt ggaatcatcg gtggggctat cttcctttat
     1621 cttctgataa ggggacgacg atatgcttaa aaaaaagcca tctattttta ttggtatgct
     1681 tgttcttgtt ttatttgtta caggaatgta cttgacgatc catacatatg gaaactggca
     1741 ttttgcatgt gcattgagga gtaagaaaat ttttgcattt atccttgtct cgctagctgt
     1801 cagcagtgcc acaatcagct ttcagacaat tacgcataac cagtttttga ctccttcagt
     1861 attgggactt gagtcgttat atgtccttgt ccaaacggtc cttttcttct ttatcggagg
     1921 agtgacgatg cttcagcaga caggtacagt ttttttctta ttgaacgttg ggctgatggt
     1981 cgggctgagt ctattgttat ttttctttct tttgaaaaaa atgagagcga atcttttttt
     2041 attactgatg tcagggatga ttttaggtac gctttttggt agtgtcagta cctttttaca
     2101 agtcatcatg gatccgaatg aatatgattt gcttcaaggc agattatttg caagctttgg
     2161 caatatccag agtcagtatc ttttgcctgc ttctttgatc attatcggct gctggtacct
     2221 gttatttcga tatcgacatg tgctagacgt tttccatctc ggaaatgaac aagcagtaaa
     2281 cctcgggata gacacagatc gttttgaatt tttgatttta tgttgtgtca gtcttttgac
     2341 agggacatca acggctcttg tgggtccagt tactttttta gggtttattg tcgcaaatat
     2401 cagttatcgt gtcttttcta cttatcgtca tggtcagcta tttatcggaa gctttctggt
     2461 agctatgctg tttctgacag gaggacagct cgcagtagag cagattttcg gctggaatac
     2521 aacagtgagt gtcgtcgttg aatttgtcgg aggaatttat tttgtcacaa aattgattcg
     2581 cgaaaggaag agtatcctat gattgattta caaaaggtca ataaactgta ccatggaaaa
     2641 tcagtggtta aagatgtaca gttaacgatt cctgaaaaga agttgactgc ttttatcggt
     2701 ccaaatggtg ctggaaagtc aacggtgttg tcgatgatca gtcgtttgat accaaaagat
     2761 acaggtgaaa tctatttaga ccataacgaa gtaaaggctt ggaaatccaa tgaattagcc
     2821 aaaaaattat cgatcctacg acaatcgaat gaaataaatg tccaaatcac cgtgaaagaa
     2881 ttagtagaat ttggacgatt tccttatacg aaaggaaaat tgacgacaaa agacgaggaa
     2941 atcgttcagg aatcactgga acaccttggg ttagaagaaa tagcggatca atcgattgac
     3001 actctttcag gcggtcaact ccaacgtgcg tatattgcaa tggtgctagc gcaagacacg
     3061 gattatattt tactggatga acctttgaac aatctagata tgaattttgc ggttcaaatc
     3121 atgcagattt taaaaaattt agtacaagaa atcgggaaaa caattgttat tgttcttcat
     3181 gatatcaact ttgctgcaag ttatgcagac gaaattgttg caatgaaaga tggacagtta
     3241 tttacgcaag gaacgaccca agaaatgata aaaaaagatg tattggatga attatacgaa
     3301 atggacatac ggatttgtga gattgaaggc cgcagattct gtctttattt ctaaaactaa
     3361 cattaggaga gaagagatga aaaaattagt agtaggtatc ttgattctag catcatttgg
     3421 tttagcagca tgtggaaata gcaacaacac cagtcaggca gacacaaaaa aaagcagcac
     3481 acaaactgaa actacattga cgataacaga tagtaatgga gaccaaatcg aggtgccaaa
     3541 taatccagaa aaagtcgtcg tattcgacaa tggttcttta gatacgatgg atgctcttgg
     3601 tgttggagat aaggtagttg gagcagctac aagcagcctt cctgagtatc tttcatccta
     3661 taaaaaagta gaatcagcag gtggaataaa agaaccagac ttagaaaaaa ttaatcagct
     3721 tcagccagat ctaatcatca tttctggccg acaaagagat tttcaaaaag atctaagtca
     3781 aattgctccg accattttcc tttctttaga tgcgaaaaat ccatgggaat ctttccagca
     3841 aaatgtcact gctttagggg agatctttgg taagcaagaa gaagctaaaa ctcaattaga
     3901 ggaattatct agtgcaatcg atcagacgaa aaagaaagca gaagctactg acaaaaaagc
     3961 actagtcaca cttgtgaatg aagggcaatt atcagcctac ggatctggtt ctagattcgg
     4021 tttcatccat gatttatttg gctttgaaca agcagatgat caaatcgaag catccactca
     4081 cggtcaaagt gtttcttatg aatatgtgct ggaaaaaaat ccggatatct tatttgtagt
     4141 agacagaaca aaagctattg gtggagacga cagcaaagat gatatttctg ccaatgaact
     4201 ggtagcacaa acgaatgctg gtaaaaatca gcagatcatc tcccttgaac cagatgtctg
     4261 gtatttaagc gggggcggtt tagaatcaat gaaactgatg atcgaagatg tgaatcaagc
     4321 atttaaatag cataaataac agaggattaa actctcatac tatgtaacaa taatgtttct
     4381 tacattctta aatagcaaga gcctatcctc aaagaagtta tcaaaaacca tccgtaaaat
     4441 cgtattgatg attttacgga tggtttttat ttatttgaga aatctttttt caacgtgaat
     4501 tcattatcta catcatacgg gttgattcta gaatggggag tggcaaaaaa tagtgtgatc
     4561 cattttttca gcatcaagat cgcctccttt gatttgaatc aaaggtacaa agcgaaactt
     4621 agataaaact taaatttaga tatttttatt ttgtaccgat ctcttcttta aacgatgttc
     4681 catctgctgc ttctcggcaa taagtccact agactagaaa atatgagaag ctattttctg
     4741 tccagcgttc ttattactca aaacaaatcg cagttgtcac aatctcttct aaacgatgtt
     4801 ccatctgctg cttctcggca ataagcccac tagactagaa aatatgagaa gctattttct
     4861 gtccagcgtt cttattactc aaagcaaatc gcagttgtca caatctcttc taaacaatgt
     4921 tcaatcagct gaccttcggt attagctcaa agcactgatt tcacaacctc tatttaggca
     4981 tgtgtctcag caagcggttg atagttgatg atctgcattt ttcgataaaa atcggcggga
     5041 agcttactcc accgttttag taattgatag aaataactct cttctgcttt gattttatac
     5101 tcgcttaata tcaatccaaa actattcgtt ttttttgaag ctaatttttt ataaatatcc
     5161 aatgctttgg ttttatcttc attgacaaag agtgttttta cttcaatata agaaccctcg
     5221 atattttgtg tttcttcgat aaaatagatg ttttttatat attccttcat agtgattcct
     5281 ccaaagaagt cttttatttg ataagtttac tctaccgaag agttgttaat aatccgtgaa
     5341 caaaaagtaa ttctttttcc aatagttgtt aaaggttttt tattttttat agtatttttt
     5401 gttatttaag aaaggaataa ggttaaacaa ataacaggtt gctttttggg tctttttccg
     5461 ttcaagaaac tgaacgaaga aaagggaaag ttgtctcttt tgtgataaga gaaatcataa
     5521 taaacgaatg acttactttc caataaattg agaacagtca gaaccagaca aattagttgc
     5581 atctgatgaa taaagtgatt attctatgac atgaggtgat acagatgaaa ttagaagtga
     5641 caaaagaagc acaagaagta ttgaagaata aattagaagc agacgatcaa cttttattag
     5701 atatcgaaaa cggtgacggt ccatttgcag aaagccaagt cagttgccaa ttggatacgg
     5761 catttcgatt gatcattgtc aaaaaagata cacaaacaga tctaagtctt tattctgtag
     5821 tggctgatac accagttgga ccaatcaaaa tcaaagacag tgcaatactt tacatggatg
     5881 atccatccac acttgcttta gaaccaactt ataatagttt acaattaaaa ggaccaagcg
     5941 gcttgagaaa aggcaacttg caagttgttc gaaaagacta gagggataaa atgggaaaat
     6001 tggcgatcat cagcgaccta catgtggaca tcaataaatt cggcgaatca gagctgatgc
     6061 agctttggca agttttgcaa aagcacaaga tcactcggct tcatctagcc ggagatacgg
     6121 ctaataaagt agaccgttgc ctagctgttg tcgaattttt cgtcaataaa ggattatcta
     6181 cgacatttca tttcggcaat cacgagttgg cagatgtgcc caatgaacag atgatggacc
     6241 attttccaga cccacatttt ttaaatgaac ggtatattgc tttaaatgag cagaccgttc
     6301 ttttagggat gaatggctgg tacgactatc agttttccga attgaaagat tacgaggcaa
     6361 tcgtacgaat gaagcgtttg tattggtatg atcggttcat ccagcgtggg aaaacagatc
     6421 tcgaggtcaa tgcagaaatg cttgcagctg caaaaaattt gctagaccag ctggaagcaa
     6481 aaaaacttga ggtgatttta tccactcatt tcgttcctaa acgggcattt atcatgtatc
     6541 aatctgctcc ttatgagcgt tggaacaaat taaatgcatt tttaggatca gaatcattcg
     6601 gagaattact tgaccgttat tcaaatatca aacaagtagt ttttggccat acgcatcgtc
     6661 gctttgaaga taaatccatc ggtcacacga tttacagctg cagacctttt ggttattatt
     6721 atgaatggca gctgacccga gattttgtct tgaaagaaca gttgctagac agctatgatc
     6781 ctatgaaatt acgtgtcctc ttgcgtgccc atcacccagc ttttcaggcc tatcaaacac
     6841 aacatttgca agaggaattt gaacaagcga tgacaatcgt tccgtattga gacagcatta
     6901 gtaatgtgta aaagaaaata ccttgtaaaa cataaggata agtaagagca gtagatccat
     6961 ttatcgtgga tatgctgctt tttttgcgga aaataatcag cgaatgttta tttgatcgga
     7021 tgatttgtaa ctcgcagagt actagatgca agcgtgtatt ctttttttga acgataatca
     7081 caaaaaaaaa tataatatac attttttatt taattataat taatattgat tgaagtctag
     7141 gcagtcaagt cacattttga tagataggag ggggacttac gaattatttt aaaggctatg
     7201 acagctgtat ttctagattg tgtttgcatc aagttgcaat aaaaactaga aatcaaatcg
     7261 ggctgataat catttataac taatcgatac ataggaccaa atataggtct atgttctttt
     7321 atttcataag tatcgtaaaa cagaattttg ctatggatta atccaatcga ctgatatgtt
     7381 tagtaaataa agaaagagga atgtcaatga tgaaaaaaga aatcgtatta acagcagcaa
     7441 tgatgttatt cagcatggta gcaagtacga cttttgtttc tgcaactgaa gtatacccaa
     7501 aggaatataa cacagaagga acgattacat ttgaagcagg agatgagggt gtaactcctc
     7561 ctgttgatcc agagaatcct gatcccaata aacctgtcga tccatcagat cctccaagcc
     7621 ctggaacagg aggggcatta tcgattgatt atggatcaaa attcaaattt gggactcaaa
     7681 aaatttctac tgcggataaa acgtattatg cagctgctga tgtgatgaac gatgggtcta
     7741 gaaaaccgac atatgtccaa gtgacagata ggagaagtac cttatctggg tggaaattaa
     7801 gtgtctctca accagaacag tttaaaactg ccagtgggga tgaactagtt ggagcacagc
     7861 tgaaatttac gaaagggcag gctgtttctt tggttgatcc aacatatacg ccgcaaacgg
     7921 tgaattctga attaacgttg acaccgggag gaaacaatac gttagcaatt aatgctaaat
     7981 caggaacagg tgtggggact tgggtctatc gatttggtgc aaatgaaaat gaaaatcaag
     8041 atgcggtaca gctttcggta cccggtaaat ctgtcaagtt agcgcaacaa tattccacta
     8101 aattagtttg gacattagaa gatacaccta acaactagtt tactgaaaag aactgttaaa
     8161 aataaatacg tagtcatatt gtcttgcgag gtaatcgagc aaaaattgtc aaaggctagg
     8221 ctaaatttgt ttggatacga atagttcatc taggaattta acgatcagga ggaaaagata
     8281 tattgaaaaa gaggaggatc gtgctcattt taagcagtct cttagtgact aatatctttc
     8341 cgatcatagg gtactctttg gaattgaatc agttggagca tggaaataga agagacgaag
     8401 aaagcaaact cacttcgaca ttcgacagtt taatagaatc caaccagaca caagaaagca
     8461 gtgaggattt aagtatttcg agtagtggag agaccactga caacgtagaa gctgagggtt
     8521 cggacaaaca aggactagaa gatgcaccaa tttctgcggt tgagctgcct gacgatccca
     8581 atattatttc tatcgataaa atttttcaaa cacctatcgg tactagcacg tccatattgg
     8641 aaaatgggaa gttactgcag ttgaacccag cagaaaggtc tcaaagagga gctatttggt
     8701 caaataagaa gattagttta ctctcggatt ttacatttaa atcttattta tacttaggaa
     8761 atcaacgaga tagagcggga gatggcatga cctttacatt gactggcgat cctagaatgg
     8821 ctagtaatcc cagtcaagtt attggatcgc caggtatggg aattggctca tattctactc
     8881 gttctggcca accttacatt gcgaatgcgc tctcgattga gtttgatacg tataaaaata
     8941 gtggttcttc tgatcgaatg gatcgagaga taactgctga taatagaggg catggacatg
     9001 tcgcttttgt cacgcctaaa ccaaataata ataattattc tggagagcat actggcgtga
     9061 cggtagctcc tacatttctt tctaatggca catggcgctt gttaataatt aaatgggacg
     9121 cggagcaaag aagtcttact tatgatttgg aaggtgtcgg tcgctcttct cggattatac
     9181 ctgatctcat taggcagttt ggttctacag aagtaaattg ggggtttact tcttcaacag
     9241 gtactttttt tcaagaaaat gctgtcgctg tcacgcgact tccatcgaat gtcacatcaa
     9301 cagctgatgt aaaagtcaac gatagtgatt atggggccat cgctgaagct ggaggaaacg
     9361 ataagataac tatcagaaat acattgaagg tcgaggggga ttttcttgaa tataagaaaa
     9421 tgcagactag tatcgacctc ccacaagaat taactattcc cgagcatatc ttgatcaatg
     9481 gaaatcaaat tgatgccaaa gatatcttga taaccggaaa tcgagtcacg ctaaatctga
     9541 cagattattt tattgctgga gatacgttaa taatcgaatt ggagacaact ttgcaggaag
     9601 taattcctga aaaagtactc actatgcatt ttgaatacct tgaaaacggg aatttgattg
     9661 agcaatcgaa tgaaataaac ctaaagatcg caaagctgaa ggagatagat atccatgttt
     9721 attataaaga taaagacagt cagattgata ttgctgaaat gaaaacaatc actgggaaaa
     9781 taggagagaa gtataaagaa actcctattg atattgaagg gtatgttttt gactcggatt
     9841 cagcgaatac agaaggcatc ttctccgaaa atacagagga tatctatttt tattacagaa
     9901 aaggcaaact ttatctctca actgctcctc aatatgtcaa ttttggaaaa cataaaatat
     9961 ccagtagacc attaagtgaa ttcggacagt tttcaggtgg gttgaaaatt atagatgaac
    10021 gggcttttgg aagttggaaa ttacaattga aacaagagaa agttcttaca aatggagatt
    10081 ttgagcttcc agaagctctt tcctttgtta cctctgaaaa tacaacggtt atagggacat
    10141 ccgctgttac gattttcgaa agtgatcaaa agggtgaaag cgatttgtcc tctcttttag
    10201 attctacagc tcatcgtgga atcagaataa atattcctgt agaaaaccaa agaatcggaa
    10261 cctttgaggg gaaactatct tggatacttg cagatgtccc aggaaattaa caggaagaga
    10321 agaatataac aaaattattg agtttcaaga agggcacagg taccataggc tcttgtgtcc
    10381 cacagagaca agattttgtt atagtcttct cttacatatg attaaaggag cgattttctt
    10441 gagaccaaaa caacaattat ttataacact cctagttatt ttaggggcac tttttaacaa
    10501 tatatcagtg tcagctagtg catttaattt ttcagtgacg ccgataactt cagagaatca
    10561 aatcgacaag agaaaaactt acttcgatct tcaacttgat ccggatcagg aagtagaagt
    10621 aaaagcggaa ttgagaaatg atacagaaaa agaagtgaaa atcgatattt ctgtgaatag
    10681 cgcaaccacc aattcaaatg tgatggttga atacggaaaa aacgagattg aaaaagacat
    10741 gagcctgatc tttgatctgg tagattatgt gagctatcca cagatagtga cgctaaaacc
    10801 taaaagtgtc caaaccgttg cttttcatgt caggatgccg aatgagcgat ttgatggtgt
    10861 attggctggt gggatcacat tccaagaaat ccagacggaa aaggaccaaa cagaaactaa
    10921 ggatcaaagc ttatcgattg agaatgaata cacctatatt attgctttgt tgatgcaaca
    10981 gacactgaac gaagttgctc cgaaccttac tcttcatgaa gttaaaccag atcaaatcaa
    11041 tgcaagaaat gtcatcttag caaacgttca aaatgatcaa aaaacctata tcaatcaagt
    11101 agttattgaa acaaaaatta caaaaaaagg acattctgaa gttttatatc aagaggaaaa
    11161 agaaggattg cagattgcgc cgaatacaaa tttttctttt ccaactgctt taaatggtca
    11221 accgctaacc ccaggtgaat atcaccttac aatgactgtt ttaggaaatg aaaatgaaaa
    11281 tggaaaattt tcgagaaaaa aaggaaatac tacgatcaac tataccaatc aatgggtatt
    11341 tgaaaaagat tttacaatag acggaaaagt agccaaggaa ttgaacacga cggatgttac
    11401 gattaaaaaa gacaataatt ggatttatat cttagtagct tcacttttct tattgtttat
    11461 tttattatgc atacttttgt ttgttttgag aaaaaaagaa gagaaagaaa agtaaggtta
    11521 agataacaaa tagtaaattt ttattattgt aggatggttg ggctcttttt ataacaatat
    11581 aaaatatacc attttattaa taaaaatgca tactagtaaa tgatataatt ctaataacag
    11641 gtttgatcgc gagaaaggcc aaataaaacg ctctccaaaa tgttaaaaaa aagacaggac
    11701 gatgtatatt atacaaacaa gaatcgctga caacagtgac tcggatccag gaaatcagtt
    11761 ttatccccag ctagttggtg aatgcatgga aagtaatata cgtagaaaga gctgatgact
    11821 aatgaattat gagttttttt taagcaaaga agatcacaga agttattcat tacttaaata
    11881 tttagaagca agctcaaatt tatcagagtc aatatcgaat gttcaagaag agttgtcgct
    11941 atcgacattt ctcttgaaaa aaacgatcga taagctgaaa catgatttac aaaagttcga
    12001 tctagagaaa aatttgcgag taaccgtcag tgaattggat atatgtctgg aaattaatgg
    12061 aaaatgttct agcaaagctc tgttatctcg ttatataacg gattctttat ctatgaaaat
    12121 ggtattggct ttctttcagg aaaaatatat ctcagtagaa aattttgcta aacagcatca
    12181 cgtgagttat tctgtggctt ataaagtatt acaaagacta aaaagaaatc taaaaaaata
    12241 tcaaattttt tttgaaaaga gaaagtt
//
LOCUS       DAZKPE010000080        11603 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000080 DAZKPE010000000
VERSION     DAZKPE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.080"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(105..629)
                     /locus_tag="ACG930_002443"
     CDS             complement(105..629)
                     /locus_tag="ACG930_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFQ0519567.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG930_002444"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG930_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFQ0519568.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG930_002445"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG930_002445"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFQ0519569.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="ACG930_002446"
     CDS             complement(2351..3031)
                     /locus_tag="ACG930_002446"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFQ0519570.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="ACG930_002447"
     CDS             3157..4026
                     /locus_tag="ACG930_002447"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0519571.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="ACG930_002448"
     CDS             4052..4567
                     /locus_tag="ACG930_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFQ0519572.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="ACG930_002449"
     CDS             complement(4614..5177)
                     /locus_tag="ACG930_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0519573.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="ACG930_002450"
     CDS             complement(5232..5411)
                     /locus_tag="ACG930_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519574.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="ACG930_002451"
     CDS             complement(5488..5997)
                     /locus_tag="ACG930_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519575.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="ACG930_002452"
     CDS             complement(6093..6473)
                     /locus_tag="ACG930_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFQ0519576.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG930_002453"
     CDS             6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG930_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFQ0519577.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="ACG930_002454"
     CDS             complement(7736..9013)
                     /locus_tag="ACG930_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519578.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACG930_002455"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACG930_002455"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFQ0519579.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="ACG930_002456"
     CDS             complement(9935..10879)
                     /locus_tag="ACG930_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFQ0519580.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="ACG930_002457"
     CDS             complement(10881..11567)
                     /locus_tag="ACG930_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFQ0519581.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3303 a         2461 c         2044 g         3795 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aat
//
LOCUS       DAZKPE010000081        11515 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000081 DAZKPE010000000
VERSION     DAZKPE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.081"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(79..2154)
                     /gene="glyS"
                     /locus_tag="ACG930_002458"
     CDS             complement(79..2154)
                     /gene="glyS"
                     /locus_tag="ACG930_002458"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFQ0519582.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="ACG930_002459"
     CDS             complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="ACG930_002459"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFQ0519583.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3457..4269)
                     /gene="recO"
                     /locus_tag="ACG930_002460"
     CDS             complement(3457..4269)
                     /gene="recO"
                     /locus_tag="ACG930_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFQ0519584.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4412..5311)
                     /gene="era"
                     /locus_tag="ACG930_002461"
     CDS             complement(4412..5311)
                     /gene="era"
                     /locus_tag="ACG930_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFQ0519585.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5326..5721)
                     /locus_tag="ACG930_002462"
     CDS             complement(5326..5721)
                     /locus_tag="ACG930_002462"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0519586.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="ACG930_002463"
     CDS             complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="ACG930_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFQ0519587.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6198..8390)
                     /locus_tag="ACG930_002464"
     CDS             complement(6198..8390)
                     /locus_tag="ACG930_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFQ0519588.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8414..9385)
                     /locus_tag="ACG930_002465"
     CDS             complement(8414..9385)
                     /locus_tag="ACG930_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFQ0519589.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10090..11469
                     /gene="brnQ"
                     /locus_tag="ACG930_002466"
     CDS             10090..11469
                     /gene="brnQ"
                     /locus_tag="ACG930_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFQ0519590.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3112 a         2419 c         2104 g         3880 t
ORIGIN      
        1 ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct gttctctggt
       61 ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta gtgacaaagc
      121 catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg gttcttctgc
      181 catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta caagctgatc
      241 ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta ctgctttgtg
      301 cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt gtttttcaag
      361 ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg gtttgaagtc
      421 ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg tcagatcttt
      481 ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg ttgtcaataa
      541 ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg acaagccaat
      601 gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca gaacagacaa
      661 aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt gacggcgcaa
      721 agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag aaaagatact
      781 atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta aatctccttc
      841 actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt tctcgccttt
      901 aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc ctaccatgtt
      961 ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca attcttcctc
     1021 agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt gcattttctc
     1081 atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa cgtattggtc
     1141 gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac gagcagtcaa
     1201 tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat tacgagcaga
     1261 aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac gttgatgttc
     1321 tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt cgaagtcgcc
     1381 agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat cttcatctag
     1441 atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga tcatttcttt
     1501 tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt attcttttgc
     1561 atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc tgtctgtttt
     1621 gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga tccagtgaat
     1681 aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga aagtgaggct
     1741 tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt gagtgtattt
     1801 cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat ctgtcgtcag
     1861 accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc
     1921 aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt ctggaatgtt
     1981 tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat cataagtcaa
     2041 ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac
     2101 aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg ccatcttatt
     2161 cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg aatcctaatt
     2221 tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg atacgggaaa
     2281 gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa ttgaatgtat
     2341 ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg atacagcgtt
     2401 tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa
     2461 aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat
     2521 cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca agacgttcta
     2581 gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact tgctggaagt
     2641 acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca ccggcacaac
     2701 ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct aatggatcaa
     2761 ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt gaaggtttca
     2821 ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca taacgcccgt
     2881 cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt ccgattgccc
     2941 gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa gcttgcatca
     3001 gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca
     3061 attttttact catctgtttt gcccctttca atttttaagc gttgctgtca ataagaatac
     3121 aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac gaataatttc
     3181 gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg
     3241 cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa accacgtgtt
     3301 ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt atataataga
     3361 tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt ccctgtattt
     3421 gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt caggtatctc
     3481 tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact tcatttgatc
     3541 aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact ggtcaatgag
     3601 gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct tatcataaga
     3661 aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat aacggtgttc
     3721 gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat agtcaaattt
     3781 tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc cgaagcgttg
     3841 cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt ggtccatccg
     3901 ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat cttcgattgc
     3961 tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat cttcttggat
     4021 gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt cacttagaaa
     4081 attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg gctgattttg
     4141 ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa agattttgac
     4201 taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg attctgcaag
     4261 ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg ccgatccaga
     4321 ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat ccagtttatt
     4381 tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg tagccgaagt
     4441 cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa agttctagaa
     4501 atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct acttgcttca
     4561 gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca acgatgatcg
     4621 tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca acgactgcga
     4681 cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc aattcagaaa
     4741 cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt gggccctctg
     4801 gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct gtagcagaga
     4861 tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt cccagcaact
     4921 cgtctggatg gatcttatcg attttattga taatcagata aactggagaa tgcacgtttt
     4981 ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca ctgatcataa
     5041 ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata aaatctccta
     5101 gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga gcttctggtg
     5161 tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc ataatggcaa
     5221 ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg cggccgacga
     5281 ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat taaacaacaa
     5341 atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac aagcggtcac
     5401 taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa aatgaaaatc
     5461 cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta tccaaacgag
     5521 aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa tcacgcccat
     5581 aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt cctcaaaaac
     5641 ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt ttttctctac
     5701 gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca aacatttctt
     5761 tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca tgtaccgcta
     5821 aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca gcagcacgtt
     5881 caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca tcttcaaaaa
     5941 tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg tctgtcggtg
     6001 catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc atgaaagtaa
     6061 cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc agcaagtcat
     6121 cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag gtaatatcca
     6181 ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac ttctgttttc
     6241 attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat caatgatttt
     6301 tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc atcggaaata
     6361 cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg atgatccatt
     6421 gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc acgactttgc
     6481 ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg ttctttcgct
     6541 ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat atcgatcacc
     6601 atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg tccaaagata
     6661 atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc tgaaggcaag
     6721 ttctcaacga aaaagctagc atgtttgatc ttgccgatat catgataata gcaagctact
     6781 cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag attagctacc
     6841 atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa taaaggatga
     6901 tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat caattcaata
     6961 tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa cccgcagaca
     7021 agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat caaaatgaca
     7081 tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg ttctgagatc
     7141 cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat caagataatc
     7201 gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac tgcttggaaa
     7261 ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag tggtgcaaaa
     7321 gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa ttggaaaaat
     7381 ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta ttttgttctt
     7441 tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg aagcaaaaca
     7501 gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag tcctagtaat
     7561 tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat gatttctcct
     7621 tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc ttctgtcttt
     7681 ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg aatcatttgt
     7741 tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg tttaaaagct
     7801 tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt cagactctca
     7861 tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata aaaattgttc
     7921 ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt tttcttcagc
     7981 gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt tgccttatca
     8041 atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa ttcaaatagt
     8101 tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta ttctggagtg
     8161 actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc gatcgttttg
     8221 ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc cttttgtttg
     8281 acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag gaaaggcaat
     8341 gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat gtgcttatcc
     8401 tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg atgatttcgg
     8461 caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg attttcttga
     8521 tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga ggcagatcaa
     8581 tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt gtcaggaaca
     8641 ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat gcatcatcca
     8701 atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt tccatcaatc
     8761 ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga cgcagataag
     8821 gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct gcttccacag
     8881 caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg attgctaata
     8941 ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg atatcatgtt
     9001 tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata ggttttccat
     9061 tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat gtgccttttt
     9121 gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct cgtttgatca
     9181 attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt tcgccaatga
     9241 tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca atcagtttta
     9301 tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc aatctaatct
     9361 ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat tcattctttc
     9421 ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct aaaagagttg
     9481 cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct aaaggtctcg
     9541 tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa gtattccgtc
     9601 taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa caaaatattt
     9661 gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa taaatataca
     9721 gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga gtcatgtaag
     9781 tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt cgaaaacgta
     9841 gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa agcgtccgtg
     9901 aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt
     9961 cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg aatctgatat
    10021 tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata attattggag
    10081 gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat ggtcagttca
    10141 cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca cttaggtcaa
    10201 atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg cgctcttttc
    10261 ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta tgacttagct
    10321 aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt aacgatcgga
    10381 ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc taaacccttt
    10441 ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt ctttttactt
    10501 gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa gtatttaaac
    10561 tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca acccatgggg
    10621 aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa tggcgtttta
    10681 gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac ttttgtccat
    10741 gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc aaaagctggt
    10801 agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct cggtgcgatg
    10861 agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca gatcactaat
    10921 ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt aggtgtcttc
    10981 actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact gttccctaaa
    11041 gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt tgcgaatgcc
    11101 ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta tccattgtca
    11161 cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc atttgtctat
    11221 caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc aaattcgcct
    11281 gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca tcattatgtt
    11341 ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta cgctggcagc
    11401 ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag tgagttacca
    11461 gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga aaaaa
//
LOCUS       DAZKPE010000082        11189 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000082 DAZKPE010000000
VERSION     DAZKPE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.082"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            151..1410
                     /gene="lysA"
                     /locus_tag="ACG930_002467"
     CDS             151..1410
                     /gene="lysA"
                     /locus_tag="ACG930_002467"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFQ0519591.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1397..2197
                     /gene="dapF"
                     /locus_tag="ACG930_002468"
     CDS             1397..2197
                     /gene="dapF"
                     /locus_tag="ACG930_002468"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFQ0519592.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2200..3081
                     /gene="dapA"
                     /locus_tag="ACG930_002469"
     CDS             2200..3081
                     /gene="dapA"
                     /locus_tag="ACG930_002469"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFQ0519593.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3078..3794
                     /gene="dapB"
                     /locus_tag="ACG930_002470"
     CDS             3078..3794
                     /gene="dapB"
                     /locus_tag="ACG930_002470"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFQ0519594.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3800..4495
                     /gene="dapD"
                     /locus_tag="ACG930_002471"
     CDS             3800..4495
                     /gene="dapD"
                     /locus_tag="ACG930_002471"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFQ0519595.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4511..5512
                     /locus_tag="ACG930_002472"
     CDS             4511..5512
                     /locus_tag="ACG930_002472"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFQ0519596.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKEKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5509..6870
                     /locus_tag="ACG930_002473"
     CDS             5509..6870
                     /locus_tag="ACG930_002473"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFQ0519597.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6830..7981
                     /locus_tag="ACG930_002474"
     CDS             6830..7981
                     /locus_tag="ACG930_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFQ0519598.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7956..9125
                     /locus_tag="ACG930_002475"
     CDS             7956..9125
                     /locus_tag="ACG930_002475"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0519599.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9300..10679
                     /locus_tag="ACG930_002476"
     CDS             9300..10679
                     /locus_tag="ACG930_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFQ0519600.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10960..11189
                     /locus_tag="ACG930_002477"
                     /pseudo
     CDS             10960..11189
                     /locus_tag="ACG930_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3728 a         1952 c         2498 g         3011 t
ORIGIN      
        1 aaccattttt attcttattt ttaaaaaaat atttcgaaat atactagaca attcagaaaa
       61 ttttgtttaa tattattcca ataaaattca aatctttatc aaatgaaatt ccaataaaaa
      121 cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat tgataattgg cggagtcaca
      181 gcaagcacat tggcagaaaa gtataagaca cctctgtatg tgtatgatga agaaaagatg
      241 agacaaacga tgctgtcatt caagcgaggc tttgtatcga aacgttttga tacaaaagtg
      301 ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc atttagttcg tgaatatgga
      361 ttcgggctag atgttgtcag tggtggggaa atctataccg ctttgcaagc tgattttcct
      421 agagatacta tctacttcca tggtaacaac aagacgccag aggaactgat ctatgcactt
      481 gaaaatgatt tgttgcatat tgttgccgat aatttgatgg aagttgaatt attagcagaa
      541 ttaagccaac gctatttaaa aaaaatctgt atcatgcttc ggttgaatgt cggagtagaa
      601 gcacatactc atgaatatat cgtcactgcg catattgatt caaaattcgg catgagctat
      661 gaaagtaaag agtgccaaca agcccttcag ttgataaaag aaagcagcta tctagagtta
      721 gaaggatttc atgctcatat cgggtcacaa atttttgatg ttactgcttg gttagctgaa
      781 atcgacaaat tgacgaatta cttaaccgat tttgaccaac ctctttcctt gaatcttggc
      841 ggagggtttg ggattcgtta tacacaaaat gatcagccga tcccagtcga agaggcacta
      901 aaaaaactga ttgaatatac ggaagaagct ttggaaaaac gaaaactgac cattcgtcaa
      961 ttactgatcg aaccgggtag aagtattgtt ggagaagctg gtacaacact atacacgatt
     1021 ggtttcatca aaaagacacc acataaaaaa tattactttg tagatggcgg gatgacagat
     1081 aatatccgtc cagctctgta tcaggcagaa tacgattgtg atttagcagc aaaactgtcg
     1141 gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt gtgaatcagg cgatgtggta
     1201 attaaagaag cttatttgcc gaaagcagaa tcgggtgatc ttttagctgt ttattccacg
     1261 ggagcttatg gatactcgat gagcagcaac tacaatcgag cgacacgacc agcagttgtt
     1321 tttgtcaata atggccaatc aagactgatt gttcgcagac aagcattttc tgatctacta
     1381 aggggggaag tttcctatga tccttcataa atataatggc tgcggaaatg attttatctt
     1441 attagattac gcagaagaca cagattatag tcaattagcc gcttctttat gcacaaaaga
     1501 aaaatatgat atagacggat tgatcgccgt aaaaatcgat ccgttggaaa tgatctatta
     1561 caacaaagat ggcagccgcg cgccgatgtg cggaaatggc attcgctgtt ttgctcgata
     1621 cgtaaatgat cagaacatga tgaatgaaca ggaattcaac gtagagacat tagcaggcac
     1681 aagaaaaatt acggtgttgg atccctcacc tttttattgc agcgtagata tgggagtgcc
     1741 agatgattct ccggaaaaaa tcaaagctaa tcaaacttat ccaataaaaa accaggaaat
     1801 agagatcaat ggtgaaaaag taacgatcac tagtttattt ttaggaacga ttcataccgt
     1861 tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa agaggtgaac tgatctgtca
     1921 tcatcctttg ttcaaagaaa aaaccaatgt caactttgta gaagtagtca atgaacaaga
     1981 attgatcgtc cgtacctatg aaagaggagt aggttggaca cttgcttgcg gtacaggttg
     2041 ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt tcagcagatc aggtagttgt
     2101 tcacttggaa caaggagact tgatgatctc tggtgaggat gcgatacaaa tggctggccc
     2161 agcagttcat gaatggacaa gaatattgga ggaatgaaga tgataaaagg ttcgatcgtg
     2221 gcgctgatca cgccgatgaa tgaagaggga tcagtagatt atgctggttt ggaaaaattg
     2281 atccaattcc atttagatga acaaacagat ggattattag ttttaggtac aacaggagaa
     2341 tcttctacgc tcacacaatc tgaggaggag cagatccttc aactgacagt aaagaaagtg
     2401 gctggccgtg tgccggtgat tgcaggagct ggaacgaata atacgaaaga aacgattgaa
     2461 aaagcgaagc attttgcttc tttgggggca gacgcacttt tggtcatcac cccttactac
     2521 aacaaaacaa gtgatgcagg actagctgct cattttacag caattgcaga agcctcaccg
     2581 attccgctta ttttgtataa tgttccttct agaacaggca tgtcgattcc aatccatgta
     2641 ttagtaaatt tagcagaaca tcctaatatc attggtttga aagaagcctc aggagatatg
     2701 gcttatgtga tggatgccgc tcggttgatt ggagaagaat tcttccttta cagtggaaat
     2761 gatgatttga tcctaccagt aatgagtgta ggaggaagcg gtgtaataag tgtatgggcg
     2821 aatatccaac ctaaaatagt ccatgaatta gtaaaagata cgcaggacgg aagatggcag
     2881 caagcaaaag aaaagcaatt aaatgcactt gaactgatcc atgccttgtt cagtgagacc
     2941 aatcctattc ctgtcaaagc agccatgtca ttattagact taccttccgg acctctacgc
     3001 ctgcctttag tttctctttc aaaagagaaa aagaaacaat tagctcagct tttgttaaaa
     3061 gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag tggacagatg ggaaatagag
     3121 tcgaagaagt tgcacaagaa agaggagata cggtccttct tttacggacg gcacctaaag
     3181 aagcaactac gcttgctttt acggaactgc cagaactgct tattgatttt tctcatccag
     3241 ataatttaga gaaaatcctt tcgtatagct tatcatatca acttccgtta gtcattggca
     3301 cgacaggtta tacacaatca cagttccaag aaataaaaga acatgccaaa catgtacctg
     3361 tgatgtatag tgctaatttt tcgttcggca tcatggtgat gaatcaacta atcaagcaag
     3421 cagctgcaat gttgcaaggc tggcagatcg aactgattga aaaacatcat agtcgtaaaa
     3481 aagatgcacc atctggtact gcaaatatgc tgcttcaaac aatccaagaa gtgcaaaagc
     3541 tgcagcccgt atacaactgg caagggaaaa aaagagaaga aaaccaaatt ggtgtacaca
     3601 gtattcgtgc aggttcttta cctggtgaac atgatgtatt gtttgctgct actgatgaaa
     3661 tatttacgat caaacatgaa tctttttcta atcgaatctt tgctgcaggc gcagtagaag
     3721 cagcggactg gttgaaagat cagtcaccag gttattacaa attagaagat ttattaatgg
     3781 acaaaggggt gtaaaaaacg tggaagctca agaaatcatc cgctacattc aaacggcatc
     3841 taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag ccaatcgaat ttaaagaaag
     3901 taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt gactatgaga cgattgctcc
     3961 ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa atcgaaactg ctgcaagata
     4021 cagcgcagtt cctttgctag atattaaaaa aattaatgct cgtatcgaac caggtgctat
     4081 tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc atgatgggag cgattatcaa
     4141 tattggtgca gtaatcggtg aaaacacgat gattgatatg ggtgctgtct taggtggacg
     4201 agcgacagtg ggcaaaaact gccatattgg tgcaggagct gtcttagcag gtgtgatcga
     4261 accagcatcg gccaaaccgg ttatcgtaga agacggcgta ctggtaggtg cgaatgcagt
     4321 gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg gcagcaggag cagtggtttt
     4381 agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct gcacgtgtat taaaaataag
     4441 tgatgatcag acaaaagaaa atacagcatt gattgctgcg ttacgcgaat tatagaggag
     4501 atggagaaaa atgcgcgaaa tagatacctg tattgtgggg gcaaccggat tagtcggcca
     4561 aacgatgctc aaagtgttag aagaatatga ttttccagta ggacgattga aattattagc
     4621 ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa gagaaacaca ctgtacagga
     4681 attgacagaa acttcatttg aaggatatga tttagcgcta ttttctgcag gtgcttctgt
     4741 atccaaagag tttgcgccaa tcgcacgaag tcagggacta tttgtcatag ataattcctc
     4801 agcatggcgg gaagattcgg atattccatt aatcgttcca gaggtcaatc tggaagacta
     4861 tacattgaat cggctgattg caaatccaaa ttgttcaacc attcaagcgg tacttccgct
     4921 taaagcttta caagaagcct ttggtatcca gcgagtcaat tattcgacct atcaagcagt
     4981 ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt acgcaaaatg acgaggaacc
     5041 agttttgtat ccttataata ttagccaaac ggtgattccg gaaatcgatc agcctttgga
     5101 aaatgggtat acaaaagaag aacagaaaat gataaatgag acccgtaaga ttctgcatca
     5161 gcctgctttg ccagtatcag caacctgcgt acgtgtgcca atcgaaaatg gacatggagt
     5221 ctctgtggca gttcaactgc aaaaagagtt tacgacggaa gaaattagag agtgtctcag
     5281 ccagtttcca gggattcaat tagaagatga tctagcagca cataaatatc cgacgagcat
     5341 tcttgctaga ggaacagata tggtttatgt tgggaggatc agaaaagaca cttctttaga
     5401 gaacggattg ttgttctata cgactgccga taacatacgc aaaggagccg ctgcgaatgc
     5461 cgtacagatt gctgcagctt taatgcagaa aatagcggag gtggcaagat gagtaatacg
     5521 ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg aagagcaatt caaaaaagtc
     5581 cgtacaattg ttctttcaga tcccaatcgc caagtgatcg ttgtttctgc tttaggcaaa
     5641 cgtacgtcag atgatgacaa agtaacagac ttactttatt tgatttatgc ttaccttcag
     5701 catcatgttg attggacacc cctttggaaa aggatttgtg atcgtttcat tcaagtaaga
     5761 gatgttcttg ccctgcagtt acctattgaa gatgaactag cacgcataca gaaacaactg
     5821 gaagacgaaa agataactga agattattta gtaagtagag gtgaatatct gactgctcaa
     5881 ctgatggctg agtatcttgg ttaccagttt attgacgcaa aagacctgat tttctttgac
     5941 tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa tcacaaaagc atttaaaaga
     6001 tatccgaaaa tggttgttcc agggttttac ggggcgaacc ctgcaggaaa agaaaaatta
     6061 ttgggccgtg ggggaagcga cattaccggc gcgatactgg cgaagatgtt gcaagcggaa
     6121 agttatgaga attggacgga tgtttcagga atcatgatgg ctgatccgcg aatcatcgat
     6181 catcctaaaa tcatcgagga aatctctttt agagaactga gagagatggc ttatatgggg
     6241 gctaacgttc ttcatgaagc agctgttttc ccagttcaag aggctgatat ccccatccaa
     6301 ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa tatcgaatca cgaaatagaa
     6361 aaggaaaatg gactgacagg aatagctgga cgcaaggatt ttctttccat cactttattc
     6421 aaacgtcata tgtccgatga aatcgggttt atctggaaag caatgagcat ttttgctaaa
     6481 catgagatat caatcgaaca tattccttca gggatcgaca atatcggagt gatcgtctca
     6541 gcagaagcga ttgccgataa gttatttctc atcacgaaag aattaaaaga aacacttggc
     6601 gtggaagaaa tcgtcgtgat cgaagactta gctttgatct ctgtcgttgg gggtccgcat
     6661 aaagaattga ttggattatc tgggaaagtg ttatcgatat tgaacaaatt agaaattcgc
     6721 acatcgatct tatcacaagg agcacaggag ttgaatctga tcatcggtgt accgaataat
     6781 caatatgaaa cagtagtgaa gggtatctat gaagggatgg tgaatacgga tgctgaaaga
     6841 atatcgaatg gcactccatc aaattcctga aatcgggttt catgaattca agacaaaaaa
     6901 atatttatat gaacaagtaa aaaacagcga ggccgttatc catgaaatcg gcgaaacagg
     6961 actactcctt tattttgata atcagcaaga agaaacgatt gcttttcgaa cagatatcga
     7021 tgcactgcca gtcaaagaag aaacgaatct ctcttttgct tctaagcatg aaggttatat
     7081 gcatgcatgt ggtcatgacg gacatatggc gatgctttta gggttgactg actttataac
     7141 taaacacatt gaggatctta tttataatgt agtactgatc tatcagccat cagaagaaat
     7201 ttccggtggc gcacaaagcg ttattcagtc aggattgttg gataaatatg aagtacaagc
     7261 aatatttggc tttcatctat ggcctggact agctaaggga gaagttttct ctcgaccagg
     7321 acctttgatg gcacaaagca gtgaaacaga cattatcatt aaaggccagt ctgcacatat
     7381 tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct gtacgatttt tgaagaatgt
     7441 ttatgatttt gaccggcaat taccggcaga gtggaatcat ctaatgaaat ttggccaaat
     7501 ccaaggtgga acgatccgaa atgttttagc tggagaagtt attgtatccg gaagtatccg
     7561 ttcttacagt tcagatatgc aaaattattt gaagagggga ttagaccatt tagcagaaca
     7621 gtttcactct acagctacta tttcttttcg ctataatgac ggctatccag ctgtaatcaa
     7681 ccatagaggc ttatatgcag cactgttaga ttcaaacaaa ctacatgaat tagatgctcc
     7741 agttcttcaa gccgaagatt ttggcatata tacgcaacaa tatccatgtg tatttttctt
     7801 tttaggtgtc ggtgataccc ctgctttaca tgatccgacg ttcgattttg atatggatgt
     7861 tttagaaaat ggtgtagaat ggtacaaaac gattcttttt acagaaaatc ttcttgtaaa
     7921 aatcgatagc agttcaaaag aggagcgagt aaataatgat gaatttatcc aatcgattta
     7981 gtcctaggct ttctagaata gaagtatcaa aaatacgaca attcgatcag caaatatcgt
     8041 cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga ttttccaact cctgaacatg
     8101 tcaagcaagc aggaatagca gcgattgaag aagacttttc tcactatacc ggaatgagag
     8161 gattagagga actgcgggaa gcggcttgta tatttcagca acagcgttat ggattaactt
     8221 atgatccgca aacggaagtt ttgacgacag ttggtgcaac ggaagcgatt gcctctgcgt
     8281 tgttatctgt tttggaagaa ggagacaagg ttcttattcc agcgcctgct tattcaggat
     8341 atcagccatt agtggaacta gctggtgctg aattgatccc gatagatact tctgacacag
     8401 ggtttgtctg tcagccggaa caatttgaac gagcatttga acaatatgga tcagctgtca
     8461 aagcagtcat tttaaactat cctaacaatc ctactgggac gacattgtct gcaaaacaat
     8521 tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt tgttataagt gatgaagtat
     8581 atgctgaatt gacttatagt ggaacgcata tgtccatagc tacttatctt ccagaacaaa
     8641 caatcgtgat aagcgggtta tccaagtcac atgcgatgac tggttggcga gtgggcttta
     8701 tttttgctca aaaagccctt attgacgaac taattaaagt ccatcaatat ctggtgactg
     8761 ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct aataaatggg gtgaaagata
     8821 gcgagaatat gaaagagcaa tatcaaacac gaagagacta tctggtccag caattggcgc
     8881 ctttaggatt tgaagtgacc cagccaaacg gtgcatttta cttgttttgc aaactcccag
     8941 ctgccattca aactgactct tggcagtttt gtgtagaatt agcggaacag gcaaaagttg
     9001 cgtgtatccc aggaattgca tttggcccag aaggagaagg ttatatccgg atttcttatg
     9061 ctagcagcat ggaaaaatta catgaggcct gcaaacggat caaagacttt ttaacagaac
     9121 agtgattcat agattttatc aaaaaaacaa tcgttaattt tgcggtatat tctgcaagga
     9181 gacgattgtt ttttaaattt agttcaaatg aacgcgtttc ttttgattca taactaatgt
     9241 aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat attcaaggag gtttcatcaa
     9301 tggaaaaaat caaagttgtc attgtaggtg catctcatgg agggcatcaa tcgatcttgg
     9361 aactattgac acgatacggt gaaaatgtag atatcacgct atttgaagca ggagactata
     9421 tttccttcat gtcatgtggt atggagctgt atttagaaga caaggtaaca gatgtaaatg
     9481 atgtacgtaa tttcagacca gaaaactttc cgcaatccaa tgttcatatt ttaaataatc
     9541 acgaagtaaa aacgatcgat gccgataaaa aaacagtaac ggttactagc gcatcagata
     9601 acgaaacaaa agaatatcct tatgacaaat tgattttgag ttctggtgtc aaaccaaaca
     9661 atctgccagt accaggagca gatctagaaa atgtctactt gatgcgtgga tacaattggg
     9721 caaccaaaat caaagaaaaa ttaaatgatc cggctattaa aaaaatcgct gtcgtaggtg
     9781 cgggttacat tgggatcgaa gcagcagaag caagccgaaa agctgggaaa gaagtcgtat
     9841 tgcttgatgt gatcgataga cctttaggca cttatttaga tgctgagatg acagatattt
     9901 tagaacaaca cctaaatgaa aacggtattg aagttttgac aaatgcaaaa atcgaagctt
     9961 ttactggtaa cggaaaagtt gaggcaatca aaacaagtga aaaagaaatc ccagcagatc
    10021 tagtcattca agctgccggt gtgaaggcaa atacagaatg gttaaaaggg atcgtcgact
    10081 tagatgaacg tggctggatc caaacaaatg aatacttgca aacgaatctt ccagatgtgt
    10141 atgcagtagg agatgctaca cttgcttatt ctatcccagc acgcaaaaaa atgccgatcg
    10201 ctttagcgac tgttgcacgt agagaagcac gttatgtagt aaaacatctt tttgaagaag
    10261 taccaaacaa accgttcggc ggagtcgtag gttcctctgc attaagtgtc tttgactatc
    10321 attttgcagc aagcggattg aatagcttta cagcagcaaa agcaggagta gatgtacgag
    10381 tgtcttatta tgaagatacg ttacgaccaa aatatgtacc agaagaacaa ggaaatccaa
    10441 aagtgtccat ccaattattc tcggatccaa tgacccatca attgctagga ggagcagtat
    10501 tatctaccta tgatgttaca ggtcaaggaa atgtattggc actagcgatc caaaacaaac
    10561 tgactttaga agaactagca gaagctgact tcttcttcca gccaggcttt gaccgacaat
    10621 ggagcatgtt gaatctagcc gctcaacaag cgttaggaga agaaccattt gtagaataag
    10681 aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct tgcatcaagt aataagaaca
    10741 gccaagtaaa aacagcttct tatgttttta acttggctgg acttattacc gcagatgcaa
    10801 gcttttgaac accgtttatt ttcaaaaaag ggactgtgac acgatttgtg taccgacccc
    10861 caaaagttag accaaaaaat ctaacttttg gaggtcggta ttttttatgg ttaaatatac
    10921 ttttgaactt aaattaaaga tcgttcatga ttatttggat ggcaaaggcg attggaccgt
    10981 aaaaatccag atcaagagat tgaagcggaa atgcttaaaa ttcgggagaa gcacaaggat
    11041 tatggctgtt tacggatgac caatgaacta agaaaccgcg gtttctctat caataaaaag
    11101 aaagttcagc gcttgatcaa gaagctagga ataaaagtaa cggcatacac gcgtaaatca
    11161 cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DAZKPE010000083         9983 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000083 DAZKPE010000000
VERSION     DAZKPE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.084"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..2142
                     /locus_tag="ACG930_002478"
     CDS             127..2142
                     /locus_tag="ACG930_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0519601.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            2144..2428
                     /locus_tag="ACG930_002479"
     CDS             2144..2428
                     /locus_tag="ACG930_002479"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0519602.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            2454..3827
                     /locus_tag="ACG930_002480"
     CDS             2454..3827
                     /locus_tag="ACG930_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFQ0519603.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(3910..5925)
                     /locus_tag="ACG930_002481"
     CDS             complement(3910..5925)
                     /locus_tag="ACG930_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFQ0519604.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5947..7161)
                     /locus_tag="ACG930_002482"
     CDS             complement(5947..7161)
                     /locus_tag="ACG930_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0519605.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            7382..8326
                     /locus_tag="ACG930_002483"
     CDS             7382..8326
                     /locus_tag="ACG930_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFQ0519606.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            8622..9566
                     /locus_tag="ACG930_002484"
     CDS             8622..9566
                     /locus_tag="ACG930_002484"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFQ0519607.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
BASE COUNT         3233 a         1800 c         1896 g         3054 t
ORIGIN      
        1 tctgtatcca ttcgatagaa atcgttcggt acagtcgtaa aaaaaatcca actgtaagtt
       61 gtaccaaaca cccctcgatt taaaagcgct accatactag aatataagta ggaggtgaac
      121 agcgctgtga actacaaaat tagttatctc ctgaaaacac caagagaaat cagtctagaa
      181 aaagcagcag agatcatcga agtaaataca agcgaggcga tcaaacaatt aactcctttt
      241 gccgaatatg tggatgatac ccgtatccgt ataaagaaat tccgagcaat cgactgggca
      301 gaaaaatttt tggatattac tcgatttgaa gctgtgtata ccgaacaaga gcgaagagat
      361 cttctttatt tgatggttta ttcgactgca acgtctgttt ctgtttttca ttttcaagat
      421 tttcttcagg tttctaaagg gacagtcctg tcagatatca aaaagataag aaatgaatta
      481 gaagtggaag attgtcagct gtcgtatact aggaaaactg gttttaggct gctagggtca
      541 gaagcaatat taagaagaga agcaaaaaat cgcactgctc gtttgatgca gtcacttgct
      601 ggaagatttg ggctcacgta tttaaccgca accctttcca ttgattatta cgccaaagtt
      661 agagatttgc tagataaaac gatttcacta tcagatcttc gattcgcacc aaatcgaatg
      721 gatgaattag cttattattt gagtttgaca accattcgaa ttggaaaaac atccatggaa
      781 ctggtaaaag atgctgaact gttggcttct cttgcagtca ctgacattag tcgacaagta
      841 ttgactggcc ttggctattc cgaacatcaa aattcggaga ttatattttt ctctctttgc
      901 ttagcatcga tcgttgaagg agatgtccag gagcctgcac ttgatttttt gctggaatgt
      961 tcttcagaag tcatccatcg catggaattc ctgatggccg tagaatttgc ttcgtttcgt
     1021 gaattattga tgaatgtctt ttatcacttg gtccctgcct attttcgtat ttcctattct
     1081 ttttatttac ctaatgtgat gatcgatcaa attaagcatc aatatgcttc catctacgaa
     1141 atgacaagaa aagcattact tccgttagaa agacgaatag ggaagagcat ccctgaagaa
     1201 gagattggtt ttttcactat actatttggc ggagagatca gaaaagcgga cgcagaagaa
     1261 agaaatagaa aaataagagc cgtgatcgtc tgtccaagtg gcattagctc ttcattgatc
     1321 ttaaaaagtg aacttcagca attattcccg atgatctttt ttacagagac taattcagct
     1381 gaccgcttac acgaggttga cgaaacttct tacgatatta ttttttctac tgtacctctc
     1441 acacttactg ataagaaaaa gtctctctat gttctgcatc caatcatgac tgacttggaa
     1501 aaaaatcagc tgatcaatca agtacaaaga gattggctga taccaggatt ttcaatgcct
     1561 tctgcccaag aattgttgtc ggcgctactg ccttatatcg aattaaaaga aggcgtagac
     1621 gaagaaaagc tctatcaagt attaaatcgt aaaatgaaca aacttttaga aaagaaggag
     1681 gatcaacgtc ctatgctatc tgaattatta acagaagaaa tgatccaatt atcggatcaa
     1741 ccaaaaaact ggcaagaagc aatcacattt gccgcacagc cgctattatc agaaaataaa
     1801 atagaagaaa gttatatcaa agctatgatc gagcgcgtgg agcagtatgg tgcgtttatc
     1861 catattggcg atcacatcgc attacctcat gctcgtccag aagatggcgt aaacgaagta
     1921 gggatgtctt tgctgaaact tcaacaacct gtggatctgc ttgataatcc agcccatccc
     1981 attagtttgt tcatctgttt agctgctatc gataatgagg cacatcttcg ggctttggca
     2041 aatttaacaa agctactttc taataaacaa aatcttcaag atttattaca cgcatcaaca
     2101 aaagaagaaa tattagcgat cataagaaaa ggagacgaat gatatgaaaa tttttgcagt
     2161 atgtcaaagt ggattaggaa caagttttat ggtagagatg aacatcaaac aagcacttgc
     2221 agatcttgga gcagatgtgg acgagtttga agtaagtcat acggatgttg gaagtgtatc
     2281 tagcgatatg gctgattatt tcttcattga gcattctttg aaagatacgc taacttctat
     2341 acctgatgaa aagctcgtac ctttgcaatc gatcattgac agcgaagaag taaaagaaaa
     2401 agtaacgaag atcttgtcaa aagaataaaa atgattcaag ggaggaacta tcaatggata
     2461 aattgttgaa tttgtttgtg tcaatcgtca gtcagccctc catcctcgtt tctttgattg
     2521 cactgcttgg tctcgttctt cagaagaaga aattttcaga agtgatccaa ggaactatca
     2581 aaacatttgt cggattccta gtactgatcg gcggtgctgg tttaatcagt aattcactaa
     2641 ccccttttgc ttcgatgttc caaacagctc tgcatactca aggagtagtt cctagcaatg
     2701 aagcagtagt ggcgattgct ttgcaacaat acggtacacc tactgctttg atcatgctag
     2761 tagggatgat cgtgaatatt ttacttgcta gattcacaag atataaattc atttttctta
     2821 caggtcaagc aatgctttat gtttcttgtc taacagcagt cattttagta agcgcggggt
     2881 ttactgcaaa tttgtggatg atcttattag gcggggtctt cgaaggaaca ctattaacta
     2941 ttacgcctgc tctttgtcaa ccgtttatga agaacatcac tggaaacaat caagttgcgt
     3001 tagggcatac cggaaatatc ggttatgctt ctagtggatg gatcggaaag ttttttggaa
     3061 acaaagaccg ttctacagag gacataaaga ttcctaaaag tttcagcttt ttgcgagatt
     3121 ctactgtatc gatcatgctc ttgatgtcga tcgtatatgt cgcacttgct ttgttagctg
     3181 gtcctggatt tgttgaaaga gaactaagca atggagacaa cgctgtaatc tttgcactga
     3241 tccaagctgg aacattcaca gctgggtttg ttatcgtcct tcaaggggtt cgaatggtgt
     3301 tggcagaaat cgttccagca ttccaaggga ttgctaaaaa actcgtaccc gattctaaac
     3361 cagcattaga tgttcctatc gtttttccat atgcacctaa tgctgtatta attggctttt
     3421 ttgttagctt ctttgtagga acactatcca tgtttgctat gataggcttg caaactacag
     3481 ttatcattcc tggggtagta ggacatttct tctgcggagc tgcttctggt gtcttcggca
     3541 actcgactgg cggtagaaga ggggcggtat taggttctgc tttcaatagc ttattgatta
     3601 gttggctgcc attatttatc cttccagtat taggagatct taaaatcgct tcttctacat
     3661 ttgccgatac tgattatcta gtaccaggac ttgtacttgg gaaactagga gaatacggtc
     3721 aaatagcctt gacagttgga atcatcgctt tctttttact tgtcgtatta tctagctttc
     3781 tttttgccgg aaaaagaaca aacattgttt ctaaagaaca gaattaagca aacttcaaaa
     3841 taaaaattgc ttggacaata tcagaagaag atttaaagtc ttctgatatg tcgcaagcag
     3901 ttttttgttt tatgcattta tttttgaata gcttgttaag acaagtggct gttttgctag
     3961 aagaggataa cttttaccat tcattttcac tgttccgcct gttctatcag aagtaatcac
     4021 gatcttatct tttgtttttt caagcgaaat ctttccatct ttgataggta gcgtacaatt
     4081 cagtgtttca aatgaatcta gattaggttg tatcataaat tcttcataac ctggctttgt
     4141 tggatacaaa ccgataaaat agcgtcctaa aagatagatt gggcttgctc cccatgcatg
     4201 gcataagctt tttccataag gatctccata catactgtac ttttcatttc ctgtttgagt
     4261 agggtcgtat tcttcccaga aagttaccgc atcatgagat aacatccctc cccaataatc
     4321 aagaatcgtt tggtagacga tattcgtctg tccgagtttg cataaagcat cttgttcata
     4381 gaatttgaaa tatggagtag taatctgtgt gatagtgtca ttcaataaga cattctttaa
     4441 gatcgattgc tgttggtctt tgttagcaaa atcgaataaa acagcgaaaa tattcgcatg
     4501 acgcgtcaca tttcttctcc cagattcata gcaatcgata aaagcgccaa gttcttcatc
     4561 ccaaaagtag tcaaataggt tttgtttcaa tagttgatat ttttcttgat agagatgagt
     4621 atgataattt tcgttctctc catatgtttc agctaagata tctccgcaag tgatcatgga
     4681 atgataggct ttcagtaata agacttgttc tgcagcaagc gttccttctt tatccatttc
     4741 agaccaatca ataaatatcc aatcttttgc tctcccataa ataaacccta attcattcgt
     4801 ttgctccatc aagtatctca ttaatgattg catcttaggg tagacgatgc gtaaaaattc
     4861 atagtctttc gtcatcatat agtggttttc gataccaatc aaccacaaga tcgaatagtc
     4921 aacgatagta ttcatatgct gcttgatttc attttgtcct cttaatgcta atatcgttcg
     4981 tttattgatt tcctcgtcaa aaaaaagata ttgattgatc atgaatgatt gatacgcatc
     5041 tccagaccaa atccagcgat ctcgtttgat accgtcgata aaaaacaaat cactacataa
     5101 cttgaaggct tcttctgata ctgaccagat ctgattcagt aaagaagaat cgcttgaaaa
     5161 agcagcttgt ttcgaaagag ataaaaattc atgaaaaact tgaagttgaa ccattccagt
     5221 agaaacctct ggtataaaca aatagcgaaa agcgcgttta cgagctttca tttttcttgt
     5281 cattcctatt tgcttatagt agcaataatc gatatccata gcttctacat cggactctcc
     5341 ataacataga gtgatagatt cgatatggtc atccagagat attagttcta cacagccatt
     5401 cactgctcgc ccaaaatcga ataagattcc tccgccaatc tccgtttcag tgactggatg
     5461 gacgcattct ttttgataat agatttgatt tggatctttt gcgatatcga cataaagcgg
     5521 actccagcca gctggatatt cttcaataaa attacttgct gtccagccaa tatctgattt
     5581 tacttcgtct ccctcgataa acatcgctgg tagccctgat gtatgtccta caaagatacg
     5641 aatttttgct ttaccagctg gacaagtcag ccattttcca catggatgtt tttgtccatt
     5701 aatttctaca tacccaactc cttggatcgt cactttaaac atggaaggtt gatcaagaaa
     5761 gtaatatctc ttaaacttga cgttccgatg gcaatcatcc atgtaccagt acgctggcca
     5821 gtcaaaacct cgttcttccc gttggaaatt ttgtagcagt ccatggcgga tctcaaagtc
     5881 tccaggatac caaagccatc tatctttatg tttttcattt gtcattttac acgacctcca
     5941 tcaaatttat tttgttgtca attgttcttt tatttcttca tctactctta tcactgtctt
     6001 tctattcgtc ctgtgtacta ctagaaggct aataagcgcg ctaatcaaca gcaagatact
     6061 gccattgacg aaaacagcaa gtgttttact cccaagagaa gcaaaagaga gaaagagcaa
     6121 accatatggt gcaatgaaag tacctaaatt agcgccaacc aataagattg aagtattgaa
     6181 actctccgcg tacttgggcg cttggatact tacttggttg aataagtaag gaatgaataa
     6241 cgaaaaagaa attcctgtta ggatcgcacc aaacccaatc acatacaggt ttatcacagt
     6301 ggcaatcaat acaaagccga ttcccatcag tagtaaagaa agtgtaagca tatagcgatg
     6361 tgcttttgtc tgaagccagc caaaacaaac tccggcagcc atacttgcca attgcatgat
     6421 tgttaagata ttcgctgcat tagtttcgtt tcctagagaa taagtcgtca ggactgtggc
     6481 taatttaatc gatacagcat tatataccac gatgaccagc aagagaaaaa taccataact
     6541 aatcatttta ggattcgttt tgattacttg tcttgttggg gctgtgccat gcgattgaag
     6601 ttcagttgtt tcaggtgtag gaacaaacaa aacaaacaag acaagaatag gtaagctgat
     6661 ggcgtagact aaaaaggtat attgccaacc gaactgtact agctgtcctg caacaaatgt
     6721 cattaaagct gcaccaaatc cttgaaatgc actttgaaaa ccaatcatag aggctcgttc
     6781 atctccgtga taaaaggcag caatcatgct gactgccaaa gaattgatca atccaaagcc
     6841 aatacctagt ccagctcttg aagctaagac aatactgtaa ctttgtgaga agagggggag
     6901 gataccacaa atcgatgcaa tcactaatcc gatgatcaca gtttgttttt gtccgatttt
     6961 cctagcaata aaactactaa tcaaaacaaa aatagtgacc ataaaagagg gagcagtcgt
     7021 taataattca acagcagata aagaacgcgt ggcataagta gctgacatac tgggaattgc
     7081 agacgtgact gcaccagcag aagtcaaaat aagagagact gacagcagag aaaatttcat
     7141 catcttttta ttcataagca tgttcctttc atttttgtaa gcgcttatca aaaatatagt
     7201 atgaagtggt tattctctca atagcggaat cacaggaagt tcatgtccca accatagaaa
     7261 gtctttatga aaccaaaaat agctttgcat ataatagcag tacagcgtga actaataagc
     7321 gaaagaaacc gcttacaaaa aggagggagt caattggaac tagctgaatt agacattttt
     7381 tttgcgtaac gaagaatcaa tcgaaactct gcagcgtgaa caaggaatga atatcaatga
     7441 tttaaactta gcttaccatc ttcagacacc gccaaaaatc caccgagggg atctatttca
     7501 acagggaaat attcatatca gtaaacaccg tcgatatgcg gaagttcccg agcatacaca
     7561 tgattttgtt gaaatcaatt atatgtatag cggtacatgt ttacaaatta ttaatggaga
     7621 aaggatagag atggaagaaa gtgacgtggt gatcattgat aaagaagcta ctcaaagaat
     7681 cgaatacaca gggcaagagg atattttaat caacatctta ttaaaagaag aaaccttatc
     7741 tacagagata ttgaatcatt tggcaagcac aaataatcta ctttcttctt ttttgataaa
     7801 tgcatcaaaa gaaaaagggg aacatacaca attcattcat tttcgcggcg gaaaaacaag
     7861 tcgtttgacg catttgattg aaaatatgct gttgatttat tttgatacat acagtcataa
     7921 gatccgttcg ttaaatctct atacatcact attactgatc gaattgactc atttattaga
     7981 acaacaaagc ttttcatcag cagatggatg cgcagaaaat gagatgctta gagtattaga
     8041 ttatatcgat aagcatttta cttcttgtac gttaaaagaa acagcagctc attttggcta
     8101 caatccggtc tatcttagta ataaattgaa aatgtatttt gatgcttcct ttcaagaact
     8161 ggttctaaag aaaaaattcg actttgcgtt ggaactgatt caagaaacga gtttttcgtt
     8221 ggaagaaatc gctaatcgta tcggatataa acaaacgact tctttattca aattattcaa
     8281 gaagtattca acatgtactc ccaatgaatg gagaaataaa cattaagaag aaaatctttc
     8341 actaaagcat atgaaggaaa attgttttag gtgcgattgc tgtcttatta tatcgttgca
     8401 gcgaattttt ttggatttat tttcagttct aaacttttgg ttgtattatc aggggatata
     8461 ggtgtaaaca tttgtcattt atctgttatg cgtattcagg aattcgtttc catcaaaaat
     8521 tataataaca actattataa ttaacatgtt gataaaatga ataaacaaga ctatactttt
     8581 catgaaagta acaaatagtt atgaaaagga gctgtttatt catgaaaaaa acaagtcgta
     8641 aagtagtaat cgtcggtaca ggttttgttg gaacaagtat cgcttatgca atgatcaacc
     8701 aaggaatctc taatgaatta gtattgatcg atgtgaatca agaaaaagca gaaggggaag
     8761 cattggacct tttagatggt atggcttggg gcgatgaaaa tgtggctgta tggtcaggtg
     8821 gctatgaaga atgtaaagat gctgatatcg ttgttatcac agctggtatc aaccaaaaac
     8881 ctggtcaatc tcgtttagat ttagttaaaa caaatgcgtc aatcatgcgc caaatcgtaa
     8941 aagaaatcat gggatcagga ttcgacggta ttatcgttgt tgcttcaaac ccagtagata
     9001 ttttgacata tatcgcttgg aacgaatctg gtctgccaac atcacgtgtt atcggtactg
     9061 gaacaacatt ggatacaact cgtttccgta aagaaatcgc attgaaatta aaagttgacc
     9121 cacgcagcgt ccacggctat atcttaggtg aacatggtga ttcagaagtt gctgcatggt
     9181 cacatacaac tgtcggtggt aaaccagtgt ttgaaattgt agaaaaagac catcgtattg
     9241 cccaagatga attagatgtg attgctgata aagtccgtaa tgctgcttat gagatcattg
     9301 atcgtaaaaa agcaacttac tatggtattg gtatgagtac tgcacgtatc gtaaaagcta
     9361 tcttgaataa cgaacaagct gtattgcctg tatctgctta tttaactggt gaatacgacg
     9421 aaaaagatat ctttacaggt gtgccatcaa tcgttgacga aaatggtgtt cgtgaagttg
     9481 ttgaattatc aatcaacgaa gaagaaaaag caatgttcag caaatcaaca agtgctttaa
     9541 gagaagtatt gaacactgta ttataagaaa caatgaatat gaactaaaaa tcctaaaact
     9601 gcttaacagc tgaaatagct gttaagcagt tttttattga tatctaatag gtaagcaaat
     9661 aaacagaatg gttaaaatta atcggtccga aaatgtatcc gtacatatga acatatgaaa
     9721 tttaatctgt tgattacaat aagcgaatcg ttatcaatgt ttatctgtgg ttaattaaaa
     9781 aatccttccg caacggcaaa tacaatgatt catatctaat tcgttcatat ttgattaact
     9841 gaataaagaa actggttttt atcattcaat taaacgacaa aaaaagtaag aaaaactgca
     9901 aaattttttt ataattttgc ataagcagat tttgatggaa aaatgacgat ttttgataaa
     9961 aaaccgttcg agagaggttt atc
//
LOCUS       DAZKPE010000084         9982 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000084 DAZKPE010000000
VERSION     DAZKPE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.085"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(65..262)
                     /locus_tag="ACG930_002485"
     CDS             complement(65..262)
                     /locus_tag="ACG930_002485"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFQ0519608.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(408..1286)
                     /locus_tag="ACG930_002486"
     CDS             complement(408..1286)
                     /locus_tag="ACG930_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0519609.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(1325..2443)
                     /locus_tag="ACG930_002487"
     CDS             complement(1325..2443)
                     /locus_tag="ACG930_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFQ0519610.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(2440..4539)
                     /locus_tag="ACG930_002488"
     CDS             complement(2440..4539)
                     /locus_tag="ACG930_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFQ0519611.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(4590..5411)
                     /locus_tag="ACG930_002489"
     CDS             complement(4590..5411)
                     /locus_tag="ACG930_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0519612.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(5408..6217)
                     /locus_tag="ACG930_002490"
     CDS             complement(5408..6217)
                     /locus_tag="ACG930_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFQ0519613.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(6238..6732)
                     /locus_tag="ACG930_002491"
     CDS             complement(6238..6732)
                     /locus_tag="ACG930_002491"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0519614.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6744..7244)
                     /locus_tag="ACG930_002492"
     CDS             complement(6744..7244)
                     /locus_tag="ACG930_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519615.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(7309..9981)
                     /locus_tag="ACG930_002493"
     CDS             complement(7309..9981)
                     /locus_tag="ACG930_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFQ0519616.1"
                     /translation="MLQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTGNMSSVTAE
                     KISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQINEAFHSV
                     VGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIHEQIIEKDA
                     PFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFLDEVHRLSK
                     ENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRRIQISVMLP
                     TFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGKLKNIIKIS
                     CADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTDRIKPFDYD
                     SILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMFRKVWVSVL
                     GKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQFLEHLPPL
                     SEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCGNYVFEALD
                     MPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGELLLLNNLT
                     TSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMSGLGISDKL
                     KDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRSFSIPNINV
                     YDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNPTIVMSEVE
                     TVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKPDEDEFYYV
                     SRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT         3033 a         2255 c         1649 g         3045 t
ORIGIN      
        1 ctttttataa tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa
       61 tctatcacca aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa
      121 tgaacataca ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat
      181 tactatttaa gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag
      241 aaaaaaggaa acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac
      301 ttagagcctt tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt
      361 actcggttaa atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta
      421 tttcttaccg cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat
      481 tcgggcgtaa taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca
      541 acaaatttat cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa
      601 ataattctat ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag
      661 gcttcaatct gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt
      721 ttttcaatcg ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt
      781 cctgaaaaat tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg
      841 aacccttcca cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg
      901 aagtatgcaa cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc
      961 gcattgacat ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca
     1021 aaattgaaat tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat
     1081 ttgcattgaa tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta
     1141 aaaggtttaa aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa
     1201 ctgactcttt ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct
     1261 ccagcttcaa ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac
     1321 ttcattaacg cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt
     1381 ctgttgaata ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat
     1441 catcgttgcc gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt
     1501 gaagatgcca acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg
     1561 cattcaattt tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat
     1621 accctaaaaa ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat
     1681 gaaaggccca cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact
     1741 cactatcccc atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc
     1801 aggtaagcgc aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact
     1861 tataatcctc ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc
     1921 tattttcttc caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat
     1981 ccttcggatg taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat
     2041 aggaattaaa gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct
     2101 ctccaaaccc attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc
     2161 catcccaata aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat
     2221 cacgaatcgt catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag
     2281 tttcttcacc agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc
     2341 ttggcaacat cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac
     2401 tctggatttt tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat
     2461 gtgaatcgtt tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg
     2521 cttttctgac aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc
     2581 ttgaccgaac ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa
     2641 tactcctttt ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc
     2701 cgatgcccag ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc
     2761 taagcgatac ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc
     2821 taatcgggtt acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc
     2881 aggaaaagtg gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt
     2941 tggattgaaa gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc
     3001 taaaaattga taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa
     3061 attaattttt ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg
     3121 tttttgatag tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa
     3181 ttgctcacca aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca
     3241 ggcaatgttt ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc
     3301 aagtccaata caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc
     3361 aaaggcgtct gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc
     3421 taatatgtcc tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa
     3481 ttttgtatcc ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt
     3541 actcagagaa tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg
     3601 atcaaaccat agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga
     3661 tgcgtaatac atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct
     3721 gccgacgacc tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg
     3781 acgatagaga tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa
     3841 atagttcaat gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc
     3901 ttcaaaagca tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat
     3961 cgtgtcctta tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg
     4021 atacgaaggc acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta
     4081 aacctgttga acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac
     4141 aatgacctta aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc
     4201 gacttcaata cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt
     4261 taaggataac gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc
     4321 agttagtaaa ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt
     4381 tgctaatgtc ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg
     4441 atagtagctg tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa
     4501 tgggtgtttg ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa
     4561 aactgcagcc tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt
     4621 cccaagacga ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg
     4681 aaacagctca atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct
     4741 tggacattca ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc
     4801 atactgatcg tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga
     4861 atttcaatta acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct
     4921 aaaacgccgc catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata
     4981 attggtgcca aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca
     5041 cgccaaactc cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt
     5101 ttgatcgcgt tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc
     5161 gatgccgcaa tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta
     5221 tgacgttcca gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc
     5281 atcatagaat aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata
     5341 gtcatcgagc gccaaaacat cttccgaacc aattttttct catctttaga aattccatca
     5401 gctaatttca ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat
     5461 cgctttgaac tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa
     5521 ttgcaataat cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa
     5581 caacggcccc aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca
     5641 tcgccatccc aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct
     5701 ctggaatatt atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg
     5761 gaataagagc ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc
     5821 ctttttgatc accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa
     5881 aagaaaaaat catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa
     5941 taatcgcatc cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca
     6001 aagaaggctc cgccgtacta gagattccga tattgacgac acccataaag atggcttcta
     6061 gtgacgcccc gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag
     6121 caacaacaat cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa
     6181 taaaaacggc caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta
     6241 aaaatcactc aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac
     6301 ggtatctgga taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat
     6361 cacttccttt gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc
     6421 cacgttcatt aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac
     6481 attagggact aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat
     6541 cgcgtcatca actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt
     6601 catcttttga atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt
     6661 tagactcttt gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac
     6721 tgctttaatc atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc
     6781 tcatcaagaa tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc
     6841 tcctttgtta attccttggt tgccaatact atttcgagca gaattggcag attaaagcca
     6901 gacaaaatag ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca
     6961 cttccgccaa ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca
     7021 aatacattca actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc
     7081 tcttgaacct tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg
     7141 tgagtcgcta ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata
     7201 taagcaattc ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa
     7261 aaaagtgtct aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat
     7321 atacggtcct aataattcat agagcagcga aagctcataa gcattgactt taaaattata
     7381 tttcatctcc attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg
     7441 tttcaaatca taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat
     7501 catcaatgcc gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata
     7561 gtaattttca tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag
     7621 aaagttcaaa cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa
     7681 gcggttaaat tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc
     7741 atcaccgtct aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc
     7801 cgaagtcgtg atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa
     7861 ttcacgtagt tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg
     7921 acgaaaaaca tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat
     7981 gttgctactt tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc
     8041 atcctccgca atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc
     8101 aatggaagtc gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg
     8161 tgtgtaaatt tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac
     8221 ttgccgtttc acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg
     8281 catatccaac gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct
     8341 gctagccgta ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac
     8401 ataatcagat aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag
     8461 cggtggtaaa tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc
     8521 taatgtacga tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct
     8581 gctaataatt tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga
     8641 tacccagacc tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc
     8701 cttatcaatg tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt
     8761 gaaattacct tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg
     8821 tttgattcga tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa
     8881 gctttctact tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt
     8941 taatggttct tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt
     9001 cagcttacca atattcccac taaagggatg agataacatt aaagacaagg cttctcttga
     9061 aacaataata tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc
     9121 taatcgttct cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg
     9181 ccgatcaaag gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg
     9241 aaccttagca gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat
     9301 aaatagaaag agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag
     9361 atagccgttg ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc
     9421 ccccttcttg tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc
     9481 acagtttaag atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc
     9541 aaaaattttt gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact
     9601 gagtccgtta ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact
     9661 tccgtcatga ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac
     9721 cgcatattca tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt
     9781 atcttccact aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt
     9841 cgaaattttc tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa
     9901 aactcgatct ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata
     9961 ataaactatc ggctgcaata tg
//
LOCUS       DAZKPE010000085         9874 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000085 DAZKPE010000000
VERSION     DAZKPE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.086"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(22..267)
                     /locus_tag="ACG930_002494"
     CDS             complement(22..267)
                     /locus_tag="ACG930_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFQ0519617.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(382..960)
                     /locus_tag="ACG930_002495"
     CDS             complement(382..960)
                     /locus_tag="ACG930_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFQ0519618.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1037..1567)
                     /locus_tag="ACG930_002496"
     CDS             complement(1037..1567)
                     /locus_tag="ACG930_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFQ0519619.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="ACG930_002497"
     CDS             complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="ACG930_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFQ0519620.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2424..2819)
                     /locus_tag="ACG930_002498"
     CDS             complement(2424..2819)
                     /locus_tag="ACG930_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFQ0519621.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2816..4228)
                     /gene="cysS"
                     /locus_tag="ACG930_002499"
     CDS             complement(2816..4228)
                     /gene="cysS"
                     /locus_tag="ACG930_002499"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFQ0519622.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4225..4761)
                     /gene="epsC"
                     /locus_tag="ACG930_002500"
     CDS             complement(4225..4761)
                     /gene="epsC"
                     /locus_tag="ACG930_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFQ0519623.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4847..5086)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5083..6543)
                     /gene="gltX"
                     /locus_tag="ACG930_002501"
     CDS             complement(5083..6543)
                     /gene="gltX"
                     /locus_tag="ACG930_002501"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFQ0519624.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6713..7870)
                     /locus_tag="ACG930_002502"
     CDS             complement(6713..7870)
                     /locus_tag="ACG930_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFQ0519625.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7904..9274)
                     /gene="radA"
                     /locus_tag="ACG930_002503"
     CDS             complement(7904..9274)
                     /gene="radA"
                     /locus_tag="ACG930_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFQ0519626.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9337..9864)
                     /locus_tag="ACG930_002504"
     CDS             complement(9337..9864)
                     /locus_tag="ACG930_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFQ0519627.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2509 a         2214 c         1784 g         3367 t
ORIGIN      
        1 aatctcaggc tcgtttgctt tttaaactgc ttcagttaaa aattcgatct caactgtccg
       61 agtaagtaca tctgaatagc tgtaagatac tcgttcaaaa gaattttctt caggatccaa
      121 atcaacaacg aatactgaag gataggtttc tgttaaaacg ccgcggcgtt ctgtttgacg
      181 ctttcttcct gtctgagcaa ccaacatgat tgggctgccg atacgacctt ctaaatcttt
      241 cttgattgaa gctaaagttg ttggcataca gttcacctct actatcaact ataccacata
      301 tttttaaaat tttcaagttt accataaaaa aaaaagaaat gcaataaaaa taaataagaa
      361 gctcattaag atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt
      421 gagttttact ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc
      481 catgtctaca aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga
      541 aaactggatt tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg
      601 ttcttgcaat gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat
      661 tgagacttca tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata
      721 gatttgattg cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc
      781 gtaagttctc aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac
      841 ataatttctt aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata
      901 cagggcagca aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat
      961 aaaataattc ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac
     1021 tgattagaac gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt
     1081 tttttaactg ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt
     1141 tattttcttg ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag
     1201 aagttcgtaa tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca
     1261 ctgtcacttg tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag
     1321 ccgtttcgtc ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga
     1381 tgcccggaac tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat
     1441 aatttgataa acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa
     1501 gctggacaag ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt
     1561 ttttcatggt ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag
     1621 caacactggc atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca
     1681 tttctttttt caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg
     1741 atcctttggc attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa
     1801 atcctgtttc tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga
     1861 catgttcgac tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt
     1921 gttttggtat gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa
     1981 aattgtgtgg atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt
     2041 ttgttcgttc aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga
     2101 ctccttgatg cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga
     2161 ctggcacagc ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat
     2221 cttcttgaag aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt
     2281 gcccaaagac gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc
     2341 gtccagtttg ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg
     2401 attgatgttt gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag
     2461 cggatcaatt cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct
     2521 tcgaaccctg ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt
     2581 ttagcatttc ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc
     2641 agcatttgct gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga
     2701 tgcagcttat tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg
     2761 taaatcgcat ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg
     2821 cttctcttct ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca
     2881 acaaatcacg aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt
     2941 cttcgatcaa ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga
     3001 agatcgaaag ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt
     3061 tcggctggtc tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat
     3121 ttgctgcatt aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca
     3181 aagcgatttt atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca
     3241 aattgtcaaa cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt
     3301 cactgtagcg gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg
     3361 gatcaacgtt tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt
     3421 tttcatcgtc ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt
     3481 tccctgtttt cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt
     3541 gcccgccacc atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt
     3601 caatatgcca accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt
     3661 ttgcttgttt ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg
     3721 tacgctgact tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat
     3781 tttcaaattt acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt
     3841 caaccaacac ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca
     3901 gtgtagcagg ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat
     3961 cagcaacttc tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta
     4021 catccgtgaa attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa
     4081 ttgtatcgaa agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg
     4141 gtccgcagac atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc
     4201 tggtcaatgt attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg
     4261 aacgactttt gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac
     4321 ggcacctgca ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt
     4381 cgcagagagc atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt
     4441 gccgcctaat gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc
     4501 aatgacgatt cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg
     4561 gatctcaaca ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag
     4621 ccggtgctga tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta
     4681 tgtcaaaacg atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat
     4741 cgctcgggta aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat
     4801 catcttctta taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt
     4861 ccgcgtggtt ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat
     4921 acgttcttgg ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa
     4981 gaccactccc agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc
     5041 tcttgtaatg atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt
     5101 taaatgtgct aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc
     5161 atgcatttgt cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc
     5221 agtttctttt tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat
     5281 ttgttctagc tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac
     5341 ttcttttgct gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac
     5401 gatttctgca gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc
     5461 gattgtcttt tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca
     5521 catgtcagta aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag
     5581 ttttttcgca tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat
     5641 caattcttgg tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat
     5701 aaagttgaac attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa
     5761 gattgattcg tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat
     5821 atgtccgaag gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt
     5881 attggcaata tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac
     5941 cgcaacagca aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc
     6001 gatattatcg gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt
     6061 attgcgaggc acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg
     6121 ttcttcaggt gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg
     6181 ttgtgcttcc cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt
     6241 gctagcaagc agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta
     6301 agggccgtat tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag
     6361 gttttccaac tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat
     6421 acgaataata aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct
     6481 tgcatttcca atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt
     6541 cattttcttc ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac
     6601 ggcttctcaa atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta
     6661 aatagtaaag ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg
     6721 attgtttagt ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag
     6781 gtttagcaaa gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga
     6841 tacgttcatt catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt
     6901 aggctactcc ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac
     6961 cagggatgac gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat
     7021 tttggaattc agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa
     7081 gcttagccaa tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt
     7141 acatttcgac agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac
     7201 gaccacgcac acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa
     7261 caaaattagg gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc
     7321 gaccgtcaat gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt
     7381 ttcgttctaa cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc
     7441 gtgaaccaaa aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat
     7501 agcctaagat gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat
     7561 tgtaaagagg ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac
     7621 cgaagagaag ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag
     7681 ctgagatatg tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc
     7741 tgttggtaaa tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg
     7801 agggtaaaaa tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac
     7861 gtttttgcat cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct
     7921 tcaacgtttc agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt
     7981 tacctaagtt gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga
     8041 ctcgttgttc aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga
     8101 aacattccgt tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag
     8161 ctaaatcaat cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt
     8221 gattctgaag aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat
     8281 tgaaatcaag acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg
     8341 cttggatctc taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag
     8401 ttgcaccgtc taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc
     8461 catgctcatg catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg
     8521 ctcgcaaaat ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca
     8581 tatgttctaa cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa
     8641 aaatggctat cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt
     8701 ggctgacact tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa
     8761 tgataacata atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt
     8821 cagcgtatag ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct
     8881 gctctgcgct ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct
     8941 gagaaacttg taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca
     9001 tagaccctgg caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga
     9061 tccgaggttc ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg
     9121 tcaaacttgt ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat
     9181 tccattttcc gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt
     9241 ggcaaacaaa ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca
     9301 tgagacatta aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc
     9361 gccttgacgt tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc
     9421 ttggccgata cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg
     9481 gaacatgata tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac
     9541 tccgtttgtc aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa
     9601 aaattcatct tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg
     9661 tttttcattt tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt
     9721 ccagcctgct ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc
     9781 agcagcatga tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat
     9841 aacttcaaat cctctttttc tcaccggttt tcct
//
LOCUS       DAZKPE010000086         9320 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000086 DAZKPE010000000
VERSION     DAZKPE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.087"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(51..719)
                     /locus_tag="ACG930_002505"
     CDS             complement(51..719)
                     /locus_tag="ACG930_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFQ0519628.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            853..1140
                     /locus_tag="ACG930_002506"
     CDS             853..1140
                     /locus_tag="ACG930_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519629.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1556..3094
                     /locus_tag="ACG930_002507"
     CDS             1556..3094
                     /locus_tag="ACG930_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFQ0519630.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3091..4056
                     /locus_tag="ACG930_002508"
     CDS             3091..4056
                     /locus_tag="ACG930_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519631.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4043..5365
                     /locus_tag="ACG930_002509"
     CDS             4043..5365
                     /locus_tag="ACG930_002509"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFQ0519632.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5428..5532
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5606..6349
                     /locus_tag="ACG930_002510"
     CDS             5606..6349
                     /locus_tag="ACG930_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519633.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6364..7356
                     /locus_tag="ACG930_002511"
     CDS             6364..7356
                     /locus_tag="ACG930_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0519634.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7368..8105
                     /locus_tag="ACG930_002512"
     CDS             7368..8105
                     /locus_tag="ACG930_002512"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519635.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8095..8817
                     /locus_tag="ACG930_002513"
     CDS             8095..8817
                     /locus_tag="ACG930_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFQ0519636.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8901..>9320)
                     /locus_tag="ACG930_002514"
     CDS             complement(8901..>9320)
                     /locus_tag="ACG930_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFQ0519637.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3054 a         1605 c         1967 g         2694 t
ORIGIN      
        1 tttacataat gatatttctg taaattaaat aaagtagtga aaaataagaa tcagtgctct
       61 aactgttcaa gaggatcaag tggttcaaat gtttctgtag tctgttttgc ttccaattgg
      121 ggcaaaacag atccaatttc cagatacttc actttattca atgtataaga tagaatagaa
      181 cagctaagta atgtatacag aaaatgtgtg agatccaaat aaagcaagga gacaactaaa
      241 ataccaaaag taatcaagaa aagacttttg ccaatcttaa tatgaaaata tttttcaatg
      301 gcttgataaa tgatatctgt tccgcctgtg cttccgccga atcgaaagac gagaccgcaa
      361 ccaatgccag aaagaatacc tgtcatcaaa ctattgatca gtagactatc tacagcaaaa
      421 tgtatatgaa ggctctccca taaatgtaaa aagaaaacta gcgcaaatgt tccgacgatc
      481 gtccggagaa aagcgtgttt tccaaaaaga aacaatgaga taagcaataa aggtaaatta
      541 aaaagcagtg aagtgacaga aggagcgaat ccaaaaagat tatgcaaaag caaagcaata
      601 ccagtaaccc caccatctgc cagcttagat ggaatattga ttcctgtcac agctaatccg
      661 tagattcctg cgcctaaaat gattccgcac aattctgtaa ataaatttaa ttttttcatt
      721 tctagcctct tttcttttga aaattttcag caacttcttt attatactga cttatactct
      781 tacttcaaga ggaaaatgaa aaaaaattat ttttggctgt ttctttttat ttatcaaata
      841 aggagtggaa aaatgcgagc agcagactta ttgacaattc ttacaaaatc acccaaaaaa
      901 acagagtatc aaggagtttt tttggctcaa gaacaaaaac tggtgcctgt gacaatggtc
      961 cagataaata aagcaaatca atttatcttt ttatttgaac acggcaaagc accacttgct
     1021 atgaaagaca tctttctttt tttgatgaag aaccgtgaga aagctgttta ttatcagtca
     1081 aaagaagaac tcattcctct ttatggagtg aaagagatag aaaataaagt ggtgatataa
     1141 gtaaaaataa gaaaacaaga cgtttatgat gtcaaaacaa ccatttttta catttttggc
     1201 aaaaaagtgt catgatacag tataatattc gttgaacagg ccaataaagg tgttctcccc
     1261 cacgagattt ctactttatt ggctgtttct ttttattaaa ataaaagttg tgtgtgtaaa
     1321 aaagatatag ctgattccaa gtgacaattt cgtatagatt tttatggtat tcgtagtgaa
     1381 aaaacgagaa ccaaaaagtt gatccgactt tgttgcttgg attctttttt tgtcagcata
     1441 tttagaggta tttttttctt ttttttgttc gtgctgtaag gttaaggcaa gacaagttag
     1501 ttgggaaaaa ggaaagaaat gtttatactt aaagaataac agaaaggaag gtcgcatgaa
     1561 taattttata caaacattaa gtgaaagaaa aggcgagttg ctggaagctg catttcaaca
     1621 tctgtccatt tctctcattt ctttgctgat tgcagcactg attgctattc ctttagcgat
     1681 ttgggcagcc aatcataaaa aaatggcaga agtcttattg cagatcacgg gtgtgctcca
     1741 aacgattcct tcacttgcct tattaggttt acttatccca tttgtaggga tcggaactgt
     1801 tccagcattg attgcacttg ttatttacgc tttgcttccg attttccaaa acacgtatat
     1861 tggtctagct gaaattgacc cgtctattga agaagcagcg gtagcatttg gtatgtccag
     1921 aatgagacgc ttgctgaaag tagagcttcc catcgcatta cctgtcatta tctcaggtat
     1981 ccgaactgcc ttagttttaa tcatcggtac ggctactttg gcagcattga tcggagcagg
     2041 tggattaggg acatttattt tgttaggtat tgaccgaaat acacctgttt tgacattgat
     2101 tggtgcgatc agttctgcct tgcttgcaat tatattcagc ggactgattc gctggttgca
     2161 gcataagaaa cctcgatatt ccatcattac tttagcagca gtggtgtgtt tatttggcgg
     2221 cgtttcttta tatcagtctg ccttgtttaa aaatgaaacc atcacgattg ctggaaaatt
     2281 aggagcggaa cctgaaatcc tgatccaaat gtataaagaa ttgattgaag acaacacaaa
     2341 aacagaagtt gaattaaaac cgaattttgg caagacgagt tttttgttca atgcactgga
     2401 tcaaggtcaa atcgatatct atcctgagtt cacaggtact gtcctagaaa gcttggtgaa
     2461 ggtacctgaa gcaatgaaaa gtgctgattt gacaaaagaa aaaacatatg acgaagcaga
     2521 agaattattg aataagcaat tcgatatgac attattaaaa ccaatggctt accaaaatac
     2581 gtatgccttg gcagtcaaga gatcttttgc gaacgaacat caacttaaaa agatttccga
     2641 tttggcagct atctctgatc agatcaaagc gggattcaca ctggaattta ttgatcgttc
     2701 agatggatat aaaggaatcc aagaagcata tggcttgaat ttttcaagtg tacaaagcat
     2761 ggagccaagt ttgcgttacc aagcaatcaa taatggagat gtcaatattg tggatgccta
     2821 ttccacagat agccagctca aggagtacga tctagtgact ctagaagatg atcgagggtt
     2881 attcccagct tatcaaggcg caccgctgat gaaaaaagat tttgctaaag aacatcctga
     2941 aatcgttaaa gcactgaata aattaagcgg aaaaataaca gaggatcaaa tgattgatat
     3001 gaattaccaa gtcaatgtcg aaaagaaaaa gccgacagaa gtagcacgaa tcttcctgaa
     3061 aaatgaagga ttagtaaagg aggaagatca gtgactaaat taatcgagtt caaacatgtg
     3121 caaaaaaagt atgatggaaa gtatgtcatc gatgacctaa atctggcaat caaaaaagga
     3181 gaaatctttg ttttggttgg tccttccggt agtggaaaaa caactacttt gaaaatgatc
     3241 aatggattat ctaaaccatc agcaggagac atctacttca aaggaaaatc gttaaatgaa
     3301 tataatctgc agaaaatgcg gtggaatatg ggatatgtgc tgcagcaaat cgctttgttc
     3361 ccgaccatga cagtcaagca aaatattgaa gtcatccctg aaatgttagg ttgggaaaag
     3421 cagaaaagag cagaccgtgt agatgaactt cttcaaaaag ttggcttatc tcctgatatt
     3481 tatcgagatc gtatgcctag agagttgtct ggaggagaac agcaacggat cgggatcatc
     3541 cgagctattg ctgcaagccc agatgtgatt ttgatggacg agccatttag cgcattagat
     3601 ccgatttcaa gaaactcatt acaagaattg gttttgtcct tacacgaaga attgggcacg
     3661 accatcgttt tcgttacgca caatatggaa gaagcaatca agctaggtga tcgtattgca
     3721 tttatgaagg atggagaaat tatccaatgt gacacaccag agcagttatt gatgaatcct
     3781 aaaaacgact acgttcggca tttctttgat gaaccgaaac agacgaaaga gtggcgagta
     3841 gaagatttag tcgtcaatgg atatttctta aatgaaatac cagaaaatgc tcgtcaacaa
     3901 gtttgctttg atacgcctat gaaagaagta tattcgcttc tttcggtgta tccaagcatt
     3961 gtgatagtag aaaagcaaag aagtattggg tcgctgacaa gtaaagaaat ctttgctttt
     4021 ttaagtcgag aggaggaagg aaatgaaaac atatgatgca atcatcatcg gttcaggtgt
     4081 gagcggctta agtgctgctt atggattgaa agaagcaggt aaaacagtac tagtggtcga
     4141 agaagatcta tggggcggga cttgtcctaa ccgtggatgt gatcctaaaa aagtcttgtt
     4201 aagtgcagta gaggcacgta atcgggtaaa acaattgagt ggaaaaggtt ttaacgagat
     4261 cccaactgcc aactgggaag aacttcaaaa attcaaacga acatttacgg atccagtccc
     4321 agaaagccga aaaaaacaat tagcagaagc tgaaatcgat catctttcag gaaccgctcg
     4381 ttttttggat gattcatcta ttgaagtcaa cgaagaagtc ttccatgcgg attacttagt
     4441 tttggcaacc gggcaaagac ctacgatctt accagtggag ggaaaggaat acttgaaaac
     4501 tagtgcagac tttttatcat tgcctgtact gcctaaagaa atcattttta tcggtggtgg
     4561 ttatattgct tttgagctag ctacgattgc caatgctgca gggagcaaag taaccattgt
     4621 ccatcataat caacggccat taaaagaatt tgaggcgtct ttggtagagg aagccgtcca
     4681 tcaaatggaa gcatctggca ttcagtttgc ttttggtgtt gaaacccaaa agatcatttc
     4741 agaaggtact cgctatcgtt tagtcggaaa agagacggaa ttagtagcag atatgatttt
     4801 ttgtgcgact gggagacagc cgaatacaga atctttagca cttgagcaag cgaatatcgt
     4861 ctttgataaa cacggaattg cagtcaatga ttatctgcaa acgagcaatc caaaaatttt
     4921 tgcgtgtgga gatattgttt caaggaaaac cccaaaattg acaccagtcg ccacttttga
     4981 aggaaattat gtagctaagc ggataacgga tgcaacaagc gaacctatca aatatccgat
     5041 tatacctacg atcgtctacg ccagtcctaa acttgctgaa gtaggagtta caaaaagtca
     5101 cgcctcttcg tcagatcaag tggtagagat ggatcttacc agttggttca cctatcatcg
     5161 tgtcaatgaa ccagttgcta aggctgaatt gacctttgac cagcaaaatt atttgattgg
     5221 tgctgcagtg attagcgagc aagcagacga attgatcgat gatttgacac tcgtcatcaa
     5281 tcaaaaattg actaaaaaag agttggatag ctatatcatg gggtatccga cattggcaag
     5341 tgatctctcc tatttattga aataatcagc atgataacta aagcgcttgt tgctttttcc
     5401 ttcttgtgct acactttaaa aaatgaatac ctgtttctgg ggatgtcgta gacgacatga
     5461 gagtaagttg tgaacttaga cccattgaac ctgtcagtta atactggtga agggagaaac
     5521 atagcagacg cttgaagcgg gttactatgt cgtgcccatt tcaagcgttt tttgttattc
     5581 atattagaag aaaggaggta acaaaatgaa gaaaaatctt tatccagcag tcagtatggc
     5641 attcatttta attatttggc agattgttgt catagtttgg aaaatacctg cctttatttt
     5701 acccggacct gctgctgtat tttctgcatt agcggcagat gcacaagtat tactttccca
     5761 ttctgtcacg acattaaatg aagcagtgct tggtttggta atagctagcg ttctttcttt
     5821 tattactgcc ttggcaatgg attattggaa gtttttagaa atgtcttttt atccgttact
     5881 agtgatttca caaatgttgc caatcatggt gttagggcca ttacttaccc tatggtttgg
     5941 tttcggtatg cttccaaaag tgatccttgt tgtcttgata agctattttc cgatcgtagt
     6001 ttctttttcg gatacattga ggaaagtatc aaaagagcaa atcatctttt tgaaaacgat
     6061 gggggcagat acagggaaga tttatcgaat atataaaata ccagcgggtt tatccggctt
     6121 cttttccggt ttaaaagtgg ctgctactta ttgtgtcagc ggagcagtcg ttggagaatg
     6181 gctaagcgct caagcaggct tagggtatta catgatacgc gtaaaaaaca gctaccagat
     6241 cgataaagtt tttgctgcga tcatttgtgt cattctattg agtttattgc tgaatggcgc
     6301 ttgttcatta ttgaaaaaag ggtattatcg tatgctttat attttttaag agaaggggat
     6361 caaatgaaaa aattatggct tttattaccg ctactgttgc ttttatccgc ttgtggcact
     6421 gcaaaagaaa caagtagcaa acaagaaata aaggatttga aaaaagtgac acttgttttg
     6481 gattatgtac cgaatactaa tcatactggc atctacctag caaaagaaaa aggctattat
     6541 aaagaggctg gtttaaatgt ccaaatcatc gaaccaggag ataattcgac aagtattggt
     6601 ctagtaggtg cggacaaagc acaatttggt gtaagttatc aagaagatgt cacttatgct
     6661 cacgcagatg gacagaatat accagtcaaa gcaattgcta cagtgatcaa acataatact
     6721 tctggattcg ccaccctatc agacagtaac atccattcac caaaagattt tgaaggaaaa
     6781 acatatgcag gttggcaaag tccaagtgaa gaagctgtct taaaagctgt gatggaaaaa
     6841 gacggcgggg acttttcaaa actgacaatg gtaggaagca atggagaagg gccagaaagc
     6901 ttaggaaaat cctcagatat ccaatggtac tttgaaggtt gggatatgat caaagcaaaa
     6961 gaagcgggta ttgaactaaa ctatatccca ttgaaagaat tagatgaacg gttagattac
     7021 tatactccgg taattattac gaatgatcaa ctgatcaaaa gtgatccaga attggtacag
     7081 tcttttatgg atgccacgaa aaaaggctat caggaagcta ttaaggatcc aaatgacagt
     7141 gctaaactgt tgcaaaaata tgcaaaagaa aatgatcgga cgtttttaga agaatcacaa
     7201 gcattcttgt caaaaaatta tacggatgat cctgagaatt ggggattgat ggaagaaaaa
     7261 gtttggcgca attatacagc ttttatgcag gaaaacggat tgatcaagca agatgtacct
     7321 tcgcaagaac tattcactaa tcagtttata aaataggagt gatagatatg tcaatccaaa
     7381 tcagccactt gaatgtagtc attgaaaacc tgaaaatatt agaagacatc catttcacta
     7441 tccctaaaga tacctttaca tcgattgtcg cgccaagcgg agccggtaag tcaacattgc
     7501 tgaaaacttt aacaggagtc cagcctatga cttctggaac gatcaaagta gacgatcaaa
     7561 aagtaactgg tctccataca gcatttagtt atatgccgca agaagatatg ttacttcctt
     7621 ggctgagcgt ctatcaaaac gttacgttat atcaaaaaat caatcatcta acaatcaatg
     7681 aagaacaagt aagggattat ctggatatct ttgggttaaa cggctatgaa cattttttgc
     7741 cggaacaatt atctggcggg atgaagcagc gaacggcctt gttacgaaca atcatgaatc
     7801 cttcttctta cttgcttctt gatgaaccat ttggagcgtt agatgctatg accagagggc
     7861 agatgcaaga ctggatgttg aagctgccta aaaaagcaaa gcggactact ttacttgtga
     7921 cgcatgatat cgaagaagca atttatttat cagacaggat tcttgtgctt tccgcccgtc
     7981 cggcacatgt gattgctgag attcaagtgc ctgaaaaacg acggtcacgt gaatggctac
     8041 tgcagcaatc agagttgaag caaacgattt atcagttatt ggcaggtgaa ttagatgtta
     8101 agtgatgctc attgtcattt agatgggagt cagagtttag cactccttca gcaggaacac
     8161 acgattttga cgatcatcaa ttgtgattcg ccagaagaat ggaaggaaaa cagacagctt
     8221 gcagcaagta agactcaagc cttaagttac ggtatccatc cttggaaagc agatagctat
     8281 acgtttgaac aagttgagcc ttttttgaaa aaagcaagga tcatcggtga aatagggtta
     8341 gataatattt ggacgaatgt accgatgact acacaaaaaa aagtatttga gcgacagctt
     8401 gcttttgcag ccataaatga gaaacctgtt gtactgcaca caaaaggatg cgaaaaagag
     8461 atcttaaatt atatccaagc ttaccctaat cactatttga tccattggta ttcttctttg
     8521 gactatcaac aagactatat tgatttaggc tgttatttca gcattggtct tgatttgaaa
     8581 aagaatccag cagtctggca actagctaaa gcagtcccaa tcgaccactt acttattgaa
     8641 acggatggac tacatgcagc agagtgggct ttagggggga ttttttcaga aaaagattat
     8701 gtctcactgc ttgaagaaca gttaaagaca atcgctgaga tcaaagagct atcagttgaa
     8761 gaagttaaaa aaaatactta tcaaaacttg gaacgtttca ttagattagg taaataaaaa
     8821 agagatgtga cacaactagt gtcgcacctc tttttggctt tctttgtata aaagtaaact
     8881 gtttgattaa taaatgaatc ttagtaccaa ccgtttgctt cccagaatgc tttcgccgct
     8941 tcccaagaac cataacgtga agtaacatat tgttctgcta ctctttcttg gtttgcagca
     9001 gagtagtcac catttaagta agaagaatct aattggtaac gtccgatgta acgtccgttc
     9061 gttgctgtgt aagaaccgct tgattctttt tgtgcgatcc attcttttgc agagcttgtg
     9121 cttgctggag tagcagcagt ttctgttaca gcaggagcag gttgtgtttc agcaacaggc
     9181 gctgcttgtt tttccgtttg aaccgtttct tgtacaacag gttgttcagc ttggactggt
     9241 gcttcttgaa cggctgcttg aggttcagca gctgcttgtg cagagccttc tgttgggatt
     9301 gttaattgtt gtcctgagta
//
LOCUS       DAZKPE010000087         8955 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000087 DAZKPE010000000
VERSION     DAZKPE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.088"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..303
                     /locus_tag="ACG930_002515"
     CDS             4..303
                     /locus_tag="ACG930_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519638.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(400..834)
                     /locus_tag="ACG930_002516"
     CDS             complement(400..834)
                     /locus_tag="ACG930_002516"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0519639.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1066..1776)
                     /locus_tag="ACG930_002517"
     CDS             complement(1066..1776)
                     /locus_tag="ACG930_002517"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFQ0519640.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1766..2626)
                     /locus_tag="ACG930_002518"
     CDS             complement(1766..2626)
                     /locus_tag="ACG930_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFQ0519641.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2631..3269)
                     /locus_tag="ACG930_002519"
     CDS             complement(2631..3269)
                     /locus_tag="ACG930_002519"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFQ0519642.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3284..3583)
                     /locus_tag="ACG930_002520"
     CDS             complement(3284..3583)
                     /locus_tag="ACG930_002520"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0519643.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3626..5110)
                     /locus_tag="ACG930_002521"
     CDS             complement(3626..5110)
                     /locus_tag="ACG930_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFQ0519644.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5130..5591)
                     /locus_tag="ACG930_002522"
     CDS             complement(5130..5591)
                     /locus_tag="ACG930_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519645.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5609..6676)
                     /gene="ulaG"
                     /locus_tag="ACG930_002523"
     CDS             complement(5609..6676)
                     /gene="ulaG"
                     /locus_tag="ACG930_002523"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFQ0519646.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6894..7664
                     /locus_tag="ACG930_002524"
     CDS             6894..7664
                     /locus_tag="ACG930_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFQ0519647.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7937..8764)
                     /locus_tag="ACG930_002525"
     CDS             complement(7937..8764)
                     /locus_tag="ACG930_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519648.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2725 a         1878 c         1396 g         2956 t
ORIGIN      
        1 aacatggatt atactgttga atttgacagt gaactactta agcaatttcc acaagaagaa
       61 catttcatgt ataaagaagc aatttcccac aaagtgacag agtatttgga gcataatttt
      121 tttcgtataa agccagtgcg tactcgttcg gcaaaaggaa tatacgagat gaaagtcaaa
      181 attaataaaa aaaattatcg catagcattt gctttaaaaa aaaatcatgt gttcattttt
      241 tatattagtt cgaatttgca aaaaattgta tttgataaag aggtgagtaa aaaaataaaa
      301 tagctgagca ttggaggata gattgagtga tactaagtct atcctcttgt ttttctaaag
      361 aactaagcta gaattttttc ttttgtacgt tattatatgt tatttgtcat taccaaaaag
      421 cacctttttt cttctagtat ctatgacata agaaatacca cccatttcct ttacttgaac
      481 aaatcctact gattcataaa atttttttgt tttctcagta tcatctgtca ataattcgat
      541 ttggactggt ccataactag tgatcttctc caaagcttca ttcaaaagca ctttgcctat
      601 tccttggcgc tgatacctcg gatgaatgag gatatcttga ataaatgcga tcgtcgcaaa
      661 atcagtgatc caacgaacga ttccgataat cttcccttcc ccattacgct ttatcagaga
      721 ttcagattgt tcaaatgctc tagctaacct tgcagtgtct tttgtgtaat tcgtccaacc
      781 aacgctctta tataattcag aaatctcatc gatcataagg gaatcaatat tcattttttt
      841 cttcctttct tatacaattc tccctctaat aatacagttc tttgactatt taatctatca
      901 catataactc tcctgtaaag attctctcga ttccttaaaa ttcctctttc cttttagaat
      961 gcatactttt tgataaataa aaaggttgtg ataaattttc ttcacaacct ctgtttctct
     1021 ctatcaagtg ttatctttta attttctacc cttaccctag catctctatt gcccgtagta
     1081 tgcatacttt ccatgtttgc gaaaataatg tttatctagt aaatattgcg ggatttcaca
     1141 tatattgggg ttgatcagct cgttttcttt ggccatcaga caaatttcat ctaagatcaa
     1201 actgttttct actgctttca taggtgaatc cccccatgtg aacggtccat gtccatagac
     1261 aagtactcca gggacttcgt ttggatctaa ttttctttcc ttaaacgtct cgacaatcac
     1321 attccctgta tgaacttcgt aagcttctct tacttcttct ttcgttaatt ggcgtgtaca
     1381 aggaacctta ccataaaaag catcagcatg agtcgtgcca taagctggca aatcgcgtcc
     1441 tgcttgcgcc cacatgacgg agtgcgtgga atgagtatga gtaatagcag ttatatcttc
     1501 aaaagtttga tacaaaacaa catgtgtggg gagatctgaa gatggtttta agctatcttc
     1561 ttctattata tttcccgaca aatctgttac caccatttga tctgcttgca tgcattcata
     1621 tctgacaccg cttggcttaa tgacgatgac tcctagctca cggtccactt cactcacatt
     1681 gccccaagtc aatttgacta atccgtatcg cggcaatgcc agatttgctt caaggacacg
     1741 ttgcttcatt gctgcaattt tttcttcaca agacatcata gccagcctcc ttcaatttag
     1801 aacttaagta gtcttttgcc tgctggattt ctcttcgaaa gtcttggctt ttttcactcc
     1861 acatttcaat cagaaatgtt ccatcataat ctagacgttt caaatgtctt aataatccaa
     1921 gaaaatcaac acaaccgcta ccaaaaggaa catcacgaaa ctggcctgaa tattcttttg
     1981 ttacagggta agtatctttt aagtggatag cagtgatata atcgatccct ttctcaagtt
     2041 ctcgagccgg attattttcc ggccatgcgg acaaattgcc taggtctgga tatacttgta
     2101 gaaaaggtga atgaatctgt tctttgattt ctaaaaattt tgaaatggag ttcataaatg
     2161 gatcatccat gatttccacg gaaagaatga tgccatattt agaagcttcc tttacgcttt
     2221 cttttattcc ttcgataaag tcttctctgg aattcattga tttctcttca taataaacat
     2281 cgtatccagc tatttggatt actttgacgc ttagattatg cgccaaatgg attgcttttt
     2341 tcattagttg tttcgctgct tttttctttt ctggatcagc agaaccaaac ggaaatcgcc
     2401 gatgcgcact taaacaaatc gaatggatac gtacaccgga gctgaacatc tcttctctca
     2461 gctcagctat cttttcttca gaccaatcta atcgtgctaa ccgctcatcc gtctcatcaa
     2521 tcgacatctc gataaaatcg aagtccattt cttttacaag ggaaaaacgt tctttccatg
     2581 aaatatcttt gggtaacgct ttttcataaa tcccaatttg agccatttcc ttacccccag
     2641 atacgaatga tctcatcttt gaagttttgt gcggccttca tcggatcatt tgctgctgta
     2701 ataccacgac cagtgataaa ggtatacaca tcgatccctt caaataagtg taatgtgtgt
     2761 ggatttaatc caccagttac agaaacatta aagcctagtt caatcagttt tttgatcttc
     2821 gataaatctt tttcacccca agtttcacca gataacagcg catcacggct ttgatggtag
     2881 attacctgcc ggataccgat gttatgccaa tccatggctt gttcaaaagt ccaattgccg
     2941 tagagttcta cttgcaattc acctatttct ttttgtgctg cctccatagt tggaatcgtt
     3001 gcacaacaaa tgactgtcat ccagtctgct cctgcttttg caacattact cgccactgtt
     3061 cctccagcgt ctgcacattt cgtatcagcg actagttttt tatctgggaa catactgcga
     3121 atacagcgaa tcgctttttg tccttcctgt aagcaaagaa ttgtgcccac ttcaataata
     3181 tctactacat caccaacttt cataacatct cctaatgcat gttctaagtc attgtgatct
     3241 aacgcaattt gcaaattcgg cctgctcatc ttagttcctt cctttacttg tttttttggt
     3301 accactttgt ttcagcaaat ttttcactga tttctttgac tgacatcaca tttttgatac
     3361 cgataactgt aactcctttt ttctctgcct gagtaaacat attcaaaaaa ttgactggcg
     3421 taaaaactac atcgtattgg ccagctgaac tttttccctc tgaaatggca caatgatgga
     3481 ttttggtaat tggtacgttt agttctttca ttgctttttc cacacttctc atcatcatca
     3541 agcttgttcc tgatccattt gcacacgata ctaaaattct catcttaatc cctccattat
     3601 gagtgttgtc taatcagatt ttcttttata ctctctgctt ttctgcatat gtgtcatagt
     3661 cttctacaat caaaaaataa ccatcaggat ttttccgata ttgtaactgc ggaatagcca
     3721 ataaaccaat gacaactacg gcaattccag cataacctag gactttcatg attactgtaa
     3781 acaatggcca agctgttgcc cagtcgaaca tcccgatata accaccgtat gttgacatcc
     3841 caatccatgt agcgaataat gctgaaccgc ctacttgtat gattcctgaa agaaacggga
     3901 acaggcaagc ggctttgaat ccacctcggt tattggcata aactgctata acggcattat
     3961 caaagaacaa cggaatgaaa ccggctatga cgatcgttgg tgatttcaat aaaatcagta
     4021 aaccaatcat caaaaactgt cccaaagcac caaacaagaa cccaatcgtt accgcatttg
     4081 gcgaaccaaa gccaaaagta gcagctacgt caattcctgg aacagctcct ggtaaaatcg
     4141 tgtttgagat tccttggaaa gattgagtta gttcatcgac gaatgtccga acacctaatt
     4201 gcaagatcgc cagatatacc gcaaaattta aagaagtcgt cataatgtag aataagaaac
     4261 tctgcccttc ttgcatgaat tgcgcttgaa tcaaataatc tttgcctagt acaatcagaa
     4321 tgatcccaaa gaaaaatagc atgagtaacg aagtagcaac catattctca ttgaaaatcg
     4381 acaagaatcc tggtaatttg atatcttcaa tttttttgtc ttgcttgatt gatctatttt
     4441 tcttttcatc ccgctttttc atccactcag ctaattttgc aaatataaag attccgaaca
     4501 tttgctgatg tgccactgca aatccggcac cttctgtcaa ttcctgcgtg attcctactg
     4561 ttaagttaga agctactgcc caataacaac ctaaaatcag tcccataaaa atcaatactt
     4621 gtatcctacc tagatcagga aagcaaaaca gtaaaatcca aaaagcggta gctgcttgtt
     4681 gaacctgaac gtttccggta gtgaaaacgg aacgcagttt cgtatatttc tgaaaacgga
     4741 ctaataagat atttaaaaca aatgcaatca gtaataaaat catcacatct ccaaaggtac
     4801 ggccaaatgt ctccattaat ccagcatcca cagcattttg tccaaaataa ggatctgtaa
     4861 ccatggcatc caaattgaac cgttccttta gtccaaccaa gattggccga aaattattga
     4921 ccaaaccacc agagccaaca gtcaaaataa agtaaccgac cgttgccttt aagaatccag
     4981 cgatgcattc atgaagcggg cgtttcagca aaatatagcc taataacacg ataaaaccaa
     5041 tcaggtatgc tggctgcgtc aagatatttg ttgcaaaata cgtccaaatg cttaacaaaa
     5101 attcccccat cttttttctc ctctatcaat taattatatt ctgccatcac aacttggtaa
     5161 tcatcgatgg agttcgtaga gatgagacgc tcaaccaatc catctgtcat taataattcg
     5221 gataattttt ggatattttc tagatgttct tctggatctt ttgctgcgag tgtaaaaaac
     5281 aaactagccg ttttctcctc attctcccct tcactttcaa aacggattgg ctgtttcaac
     5341 ttggtaaatg aaatagctgt tccaaaaaca ccatcacttt tttctgaaga atgcggcatt
     5401 gctacttgag gtgcgatcac aatataagga ccgtattttt ctacacaatg gatgatctcc
     5461 tccacatacg tttcatcaat aatttcctta tcgatcaata caagacagct ttcggcgata
     5521 gcttcacgcc aatccgtgat ttctttatct gggtaatgaa tcaattgatg gtcaaaaaag
     5581 tatttcagca agaaactccc cttctttctt ataaaaacga cggaaacggt gtatcatttt
     5641 caatcgagaa gacatcttca aatcctcgat aaaaattaaa ctcaagatca tctttgtttg
     5701 tcggatagat gaatttcccg cctacttgcc agatataagg tttaaatcca tacttcaggc
     5761 gatccttttt gaatttccaa atttcagtga tctcttttgg atcagccata aaattagacc
     5821 aaatatcgta gtggacagga atcactactt ttgcattcaa tgactccgcc atgcgcagca
     5881 tatcaacaga agtaactttg tctgttatcc ctcgtgggtt ttcaccatag gcccctaaac
     5941 agacatcgat tttgtgttca ttaccatgtt tggcaaataa attggagtaa tgtgaatctc
     6001 ctgcatgata aagattccct cctgatgttt cgaataaata gtttactgca atttgatcca
     6061 tctcctgagg catttttcct tttaatacct cttctggatc ttcacaagtg accaacgctg
     6121 tccgatcaaa cgcttctaaa gctactacat tgatgtcttt gattttgact gcatcacctg
     6181 gctttactgt aatcgttttt tcttcaggaa ttccccattt ttgccacgtg cgaaccactt
     6241 cttttggccc aatgaatgtt gcttcaggac aattttgatg aactgctgcg gctgtatgga
     6301 tatctagatg atcggaatgg atatgtgtaa cgattaaagc gtctacattt tttatcgcaa
     6361 aaggatcgat tacgaaaggc tgagtacgta aattaggctg catattttga acgccactca
     6421 tacgcatcat ctgatggcct tttttcatca tgccattccc atgactacgt tttcccgtcc
     6481 cacaccatag atcacataaa atattcgttc cttcatgact tttcagccaa attcccgtac
     6541 agcccagcca ccacatagca aaagttccag gatccactac ttctgtttcg atttcttcat
     6601 tcaagtatgt gccccactca ggaaatgttt ctactaacca cttttctttt gttacttcat
     6661 tgacagtttt actcatttgc ttgctccccc catatcgttg ttccaactta caagtaaata
     6721 ttaatgtgta tcagcatcca tgaaaaccct tttatatgac cgtttgtttt ttatatgatt
     6781 ttctttcagt aatcaatgat tgtttcagta taataaagac agatatgaat gtttaaatga
     6841 acaactagtc aaataaatcc atggatcaag atgtccctca ggaggcaaaa gtcatgaaaa
     6901 actcacttgt caatattgaa aaacgtcaaa aagaaatttt ggaactgctt cagcagactg
     6961 aacaactatc aactttcgaa ttagctgaat cccttgatgt atctattagt acgatacgaa
     7021 gagatttaaa tttattagaa gaaaaaaacg agatcatacg caattacggt tattgttctt
     7081 ataattacaa aaaccagact gattttgatc aatctggtcc tgaaaggatt aaacaagcga
     7141 ttgccagaga agctagtaaa tacattaacg attatgatac gctgtttatc aattctagct
     7201 cgactgcgtt gaaaacactg gattttcttc aatctaacca tttgacagtc attacaaaca
     7261 acgtgaaaat caattactct ccgcacaaag ataattgtag ttatatttta actggtggag
     7321 agatgcgctt tccaaaagaa gcactagtgg gcgacatcgc attaaatacg atttcttcag
     7381 tcaatgcaga catttgtatc attggctgta gcggagtcga tgtagtacat ggggtcacaa
     7441 caaagatatt aaatgaatca acgatcaacg aaatgatggt caacaagaca atcaaatgta
     7501 agattttagt cgctgatcat cgaaaaatcg gactgacatc aaagttcaag attgctgata
     7561 tttcagtctt tgattatttg atcactgata aattttgttc tgaaaaagta ttagaggaga
     7621 tcagaaatac ggggataaaa accattcaag tagattcatt ttaagaacca ggacgtaaat
     7681 atgtaaatag gattatcaaa aaaatgaata acaaatttat cgataaatga aaaacacgct
     7741 acgctcaaat tgataaagga atcccaagat gtatccatcc aatcgatacc atcataatct
     7801 attgcttctt ttataaccgt tatatgttgc ctaaatagga atcaaacaat atcgaaaaaa
     7861 ggaggtatga caaaagtcac acctcctttt ttcgaataaa cggtattcaa atcagaacac
     7921 tgatttcaca accactttat ttcaggtcgt tttcaatcac ctttaccgcg taatcatttc
     7981 cgttgaaacg cgctattttt tttgcgtcca tatatctttc taaataatca tcttctccta
     8041 attgcttatg gcaagaagca atttcataaa gcaagtattc caatgcataa gtcgatttat
     8101 gtttcttatt atactcaata cccttctcac ataattggat tgctttatca taatcctcga
     8161 ttttacggta ataggtggcg atatcataat atacaatgca gaccatcaga ttatcaaaat
     8221 cagtctcact caatatttta agtgtacgct ccacataaac tttcgcaaaa tctaattctc
     8281 cttttgacaa gtagatcatt gccacgtttg cagctgcttg taagtgatgg atatctgttt
     8341 cggtcgtttg ttccaacact tgattaaaat aaaataatgc tgcatctggt tttttcgcat
     8401 aaagatgatc aagcagtcct tgataaaata aaatttgatt taaaagatca gaattactta
     8461 ctttttcctg atcgatcgtt tgtaaaattt tataagattc ttggtatttt gatacagaat
     8521 tcaatgattg aatctcattt atttttttcc tgattttgtc ttcttctgtt tctactaata
     8581 tatcggagat ctcgacattc agctttttgc aaagcgcact taagatattg atgcctggcg
     8641 acatattctt gttttcgata ttgctgacag ttgcttgttc acaaatgcct tctgctaatt
     8701 gtacttgtgt taaccccttt ttctttcggt attcttttag taatgctcca tctactttaa
     8761 tcaaaacaat ttccttccct ttaaaaaatt atttctcctt tatatcatac acaaaaaaaa
     8821 gttctaaaca accaaaaatg tttagaacag aataaaaatt ttaattttaa aataatattc
     8881 aaattaaaca actggcgtat ctgctccttg atttcttttt gtgttatctg aataattatc
     8941 gtttacagtt ataac
//
LOCUS       DAZKPE010000088         8950 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000088 DAZKPE010000000
VERSION     DAZKPE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.089"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            446..1018
                     /locus_tag="ACG930_002526"
     CDS             446..1018
                     /locus_tag="ACG930_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0519649.1"
                     /translation="MTENKATQERTPQERLQKEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            1163..1867
                     /locus_tag="ACG930_002527"
     CDS             1163..1867
                     /locus_tag="ACG930_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0519650.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            2095..2433
                     /locus_tag="ACG930_002528"
     CDS             2095..2433
                     /locus_tag="ACG930_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519651.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2418..3272
                     /gene="lgt"
                     /locus_tag="ACG930_002529"
                     /pseudo
     CDS             2418..3272
                     /gene="lgt"
                     /locus_tag="ACG930_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
     gene            3419..3652
                     /locus_tag="ACG930_002530"
     CDS             3419..3652
                     /locus_tag="ACG930_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFQ0519652.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3850..5754
                     /locus_tag="ACG930_002531"
     CDS             3850..5754
                     /locus_tag="ACG930_002531"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0519653.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPTEKVKIS"
     gene            6108..6473
                     /locus_tag="ACG930_002532"
     CDS             6108..6473
                     /locus_tag="ACG930_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFQ0519654.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANEE
                     ILSAVQAFLKLSENSSMKA"
     gene            6490..7101
                     /locus_tag="ACG930_002533"
     CDS             6490..7101
                     /locus_tag="ACG930_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFQ0519655.1"
                     /translation="MLQNILSALAVYISTSIDYLFILLIIFSQNHTKKGLRQIFFGQY
                     LGTGILVAISLFAAYVLNFIPQDWIIGLLGLIPIYLGIRVAFVGEEEEEEGEVVEKLG
                     SRGTNRLFWTVSLITIASGGDNLGIYIPFFTSLSFSEIVTSLIVFAISVAVLCYISYK
                     FAKISFVSETLEKYERIIVPIVFIGLGIFIMIENGTIQTILGL"
     gene            7129..8790
                     /locus_tag="ACG930_002534"
     CDS             7129..8790
                     /locus_tag="ACG930_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0519656.1"
                     /translation="MSENKKYHEWILEGIDCANCADKVERGVAKVAGVANSSVNYMTE
                     TLSFEVTEEKEYLVLSNVQQKVKKLEPDITLKNKVDGRLIEINPALIKKSNLKDDKKN
                     YEWILEGIDCANCAAKVERGVATVPGVTNSSVNFMTETLSFEVAGENKTDVLASVKQT
                     VGTLEPDVVLRKKSDGTLIEHGTDSNKNSTSNKSISDKDETNQKQTNRAYLASLLGNK
                     TKITLIRLILGLGILATGIFLPMDGQASLGLFILAYLITGYDVVGRAIRNIFRGQVFD
                     ENFLMTIATLSAFYIQEYPEAVAVMLFYQVGEVFQDIAISKSRRSIADLMDIRPDYAN
                     LVTGNNVEKVAPEAIKIGNIILIRPGEKVPLDGKVVEGASAMDTSALTGESVPRSVKP
                     EDTILSGFINKNGLLKVVVEKPFSESTVKKILDLVQNASGRKAPTEQFITKFSRYYTP
                     IVVIAAALLAIVPPLLVPGATFNEWIYRASIFLVISCPCALVVSIPVGFFGGIGSASR
                     KGILVKESNFLEGLNDLKYVVMDKTGTLTKGFCCKVLNLLSNKVE"
     gene            8818..>8950
                     /locus_tag="ACG930_002535"
     CDS             8818..>8950
                     /locus_tag="ACG930_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFQ0519657.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     "
BASE COUNT         2883 a         1445 c         1958 g         2664 t
ORIGIN      
        1 aaaaaaattc ttttcaattt ttatttatgg tgtgacataa ataaagtaaa gttattcttc
       61 taggttaatc ttattaatgc tctttctcac tagtgttgca tgcaacacta gtgagaaaga
      121 gtattaaata tactgcaagg taagacattt ggtaattgaa gaataacaag caaaaaaata
      181 gcagtcaggt ctcttgacaa agtatagttg ctattctttt tttaggccct actttaatga
      241 aatttttgtt tggaggggac gacttcattc ctttgattat ttcagttgaa tttaatagag
      301 aagcctggcg tctattaaga aatacttttc ttgatgagcg tcaatttttt taacggaaat
      361 ctatcctata ctaaattcag taaagaaaaa ggaggaatca aagaaagcta ttttaaacaa
      421 accaaaatta taggaggaat aaatcatgac tgaaaataaa gctactcaag aaagaacacc
      481 ccaagaaaga ttgcaaaaag aacaagaaca caaggaacat gttcatcata cgaaaattaa
      541 tgcagcggcc attgcggatc atcttttagg caacatgcat acattacatg tgaaactgca
      601 ccaatatcac tggtatgtaa aaggagccaa tttctttacg ttgcatgaaa aatttgaaga
      661 gttgtataac gaaaatgaaa aatggttcga caaacttgcg gagcgtctaa ttacttctgg
      721 gcataaacct gcttcgacaa cggttgaatt tgaaaaatat tcgatgcttt cggaagatgc
      781 agttaataaa tacgctaaag cagaagacat ggttgaaaat attatcgagg acttcagaag
      841 cactcgtgac ctaactattc gcgcgattcg tttagctcaa gacgagggtg acgatgcttt
      901 agaagataca ttgattgctt ttaaaaatga cttagacaag aacatttgga tgctgcaagc
      961 gttcattggt aaagaagcat tagaagatga tgacgctctt gatgaggatg aagattaagg
     1021 taaaagtaga agctgattta gggattggaa ttctttccag tcctttttcc attttcttga
     1081 tgtgcatcaa tttttttgta gtaagagact tatataataa aagcagcgaa tataaacaaa
     1141 ataaataaag ggggagaatg aattgactaa acatacccat catgaaattg gcgaccacgc
     1201 agcctgtatc cgcttggttc caatattcaa tcacttagag gatagcgcga tgaattacat
     1261 tgctgaaaaa gcccacacga aacagtatca aaaaggagag tttctgtttc gttcacaaga
     1321 aaaagaggat actttatata ttatcaatcg tgggaaaatc cgtatttatc gattggcaga
     1381 ctctggcaaa gagcagctag tgcggatctt gaaccctggt gatttcaccg gagaatggac
     1441 cttgttcaac ccggatgcag tacacgagga atatgccgaa gcaacccgag ataccgttgt
     1501 ctgtatgatt cagcaaaaag atgtccaaga ttttctggaa caatacccag ctatttcttt
     1561 aaaactattg gcggaaatgt ctaaacggtt agaaagttca gaacgtcaaa cgacacaagt
     1621 agccgtggag agtgtcatta cccgtttagt tttgtttttg gcagaaaatg tggaacctga
     1681 aatgggcaac tctcccacca tcaccctgcc gatggcaaaa aaggacattg cttcctattt
     1741 aggaacgaca cctgagacca tcagtcgcaa atttggagaa ttggaggacg aaggattgat
     1801 tcaacagctg tctgggaaaa ggatcaagat tcaggattta gatgatttat tgctttacag
     1861 cgaataatcg gacacacttt tttctacacg ttggtgttct gtcgctcttc attaacaacg
     1921 ggacagaact cagtgctttt gcttccatct gtccgttttt ggctttttta agacagaact
     1981 accttcattc attggaaaaa taaaagcaca aacatgataa ccctcaagtt tttttgtttt
     2041 atttttcttt aagatagggt tgtcgaacaa aacgtaaaaa taagtagggt gaatgtgcat
     2101 tgtttttggg tgatagttgc catcacgttg tcagcagcgg gggcattctt tgtcgtccct
     2161 ttcaccaaga acacgattgg cggcgaagca aaaacgtcta acgttgttga ggcagatagg
     2221 ttagctatgg aaaaagaaga ggaagttgta aaaggagccg gcgtaatcgg acacggaaaa
     2281 gtggcgtatt acgaagcgag tgaccaggga gataaaagtg tattcactgt ttggtttcca
     2341 tggagcttag ccggaatctt gttcagcatc accatgacta gaatgacgcg aaaaattgaa
     2401 gaaatggagc aaatagaatg ggattcgtat taggcgtttt gaatccccat gtggtggaga
     2461 ttggttctgt tgtgattcat tagtatggag tcattattgc agcgggcata ttagcggctc
     2521 tcgagttgag caccaaggaa gcaaaaaaaa aaggactgga agaggatacc attatcgata
     2581 tggccttatg ggcaattccg attggactcc tcggcgctcg gctttattat gtgttatttg
     2641 aacttggtta ttatctgcaa aattcaggac aaatccttgc gatttggaat ggcggcattg
     2701 cgatttatgg gggattgatt gcaggaggga ggacgctata ttggtatgca aagaaaaaag
     2761 gtacttcttt ggcactcgtt cttgatattt tagcgcccaa tgtattgtta gcccagtcca
     2821 ttggtcgttg gggcaatttt atgaatcagg aagctcatgg tggaccggtt actcgtcaat
     2881 tcttggaaaa tctttattta cctgaattta tcattgaaca aatgaatatc aatggtacct
     2941 actaccatcc gactttttta tacgagtcat tgtggagttt gttgggcttt gtcctcatcg
     3001 tcactatacg gaaccgaaaa cagcttttgc gtcaaggaga agtcgctttg agttacgttt
     3061 tgtggtactc agtgggtcgg ttcttcattg aaggtatgcg aacggacagt ttatggattg
     3121 gcgagtggat ccgcgtttcg caagccttgt ctctggccct gtttattggc gcgattgtag
     3181 tatggtttat acgcagacaa gattatccac caatttctta ttattctgat ggcaataagg
     3241 agcagaaaaa gactattaag atggtgaatt gagcaaaaag ataaaaagaa gtgcaaaact
     3301 tgatatgcgt caattttcgt ttgctaaaag tgagctatac tacagttgta aagaggaaaa
     3361 ggcagtgttc attaatctgc tgccgataaa ataaaaacac ataaaggaga taggaattat
     3421 ggaaaaagct atattgcaat tagaaacgtt gtcttgtcca agttgtatgc aaaaaattga
     3481 aggtgccgtg aaatcagtta acggtattga taaagacagc attaaagtat tattcaactc
     3541 cagcaaagtc aaaaccaatt ttgattcagc tgtcacttcg attgaagaga ttcaaaaagc
     3601 tatcgaaaac gtaggctatc cggttcttaa agcaaaagtc aaggccgttt aacagattaa
     3661 atgaactagg caattctgga agaaaagcta tttttccagg attgcttttt ttgttgcaat
     3721 ccgattcgag gtgcttagaa acgataaaag agaactttct aaacttgatg tcagtcaatt
     3781 aattacttag gcaattatct tatactgtgt ttatcaataa aagagaaatt aaatttggag
     3841 ggaaaaagca tgcaacaata tatattaagc aagaaaaatg ttatcaccgt catcagtgga
     3901 ttgttaatcg tactcggttt cttcagtcac tttgttttag aaaacgtagg actttcagag
     3961 tggtctttga tcatcgcctc tgtctttggg attacgccaa ttgccattca agcgtttcaa
     4021 gcaatgaaag tcaaagtcat cagtattgat gtcttagtca gtattgcagc gattggtgcg
     4081 ctttttattc aaaattatga agaatcggct attgtcacgt tcttattctt attcggacac
     4141 tacttggaac aacgaacatt gaaccaaacg cgatctgcta tcaaagaatt gactgaaatg
     4201 gcacccgaaa gcgccttgaa acaaatggat aatggcgaat ttgaagaagt agaagtggat
     4261 gatatagatg aaggggatat cttgctcgtt aaaacgggtg cgaaagttcc agtagatggc
     4321 atagtcctta cgggtgaagg gcatatcaat gaagctagca ttacaggtga agctattccg
     4381 gtcaacaagc tagctgatgc agaagttttt gcaggaacca ttttagaaaa cggaacgatt
     4441 caaatcagag ctgaccgagt tggtgaggac accacatttg gaaaaattat tgaactcgtg
     4501 gaagaagcac aagattctaa atccgaagcg gaacggttca ttgatcgctt ttctaaatac
     4561 tacacaccag ctgtcttggt tctggcaatt gttgtatggg cgttcagtca aaatattgag
     4621 ttagcaatca ccatcttggt tctaggttgc ccaggcgcat tagttatcgg agtgcctgtc
     4681 tcaaacgttg ccggtattgg gaatggtgct cgtaacggtg ttcttttaaa agggagtgaa
     4741 gtcattcaag acttcagtaa tgtggataca attgtatttg ataagacagg tactttaact
     4801 gtcggaaacc caaccgttgc agcgactgaa ctgtatgaaa aagatcctgc tgaaacgctt
     4861 ggctatctgg ccagtgtgga acgggaatca gatcatccat tagcaaaagc ggtcttaaat
     4921 caaattggag aaacaaactt ttatcctgtt gaaggaactg aagttgtgaa aggcggcgga
     4981 atcgtttcaa gtgtagctgg acatagagtg gctgttggga atgtggcctt gatggaaaaa
     5041 gaaaatgtca ctctcagcaa aaaagtgcaa aaagatgtca aacggtttga acaacaaggg
     5101 aactctctcg ttttgacagc ggtcgacggt gaattaaaag tactgatggg cattcgcgat
     5161 caagtccgtc cgggtgtgaa agctaatttg caggaattaa aagacttggg cgtgaaaaat
     5221 ctagtcgttc tttcaggaga taaccaagga accgttgatg tggtcgccgg cgaacttggt
     5281 ttgaccgaag ctcacggcta catgttgccg gaagacaaat cggcttatat cggaaaactt
     5341 caacaacgtg gtcaaattgt agcctttgtt ggagatggcg ttaacgatag tccgtcctta
     5401 gctttagcag acattggaat cgcaatggga agcggaacgg acgtagcgat tgaaacatcc
     5461 gatgtcgttt taatgaactc gaacttcagc aacttgcctc acgcattagg attagtaaaa
     5521 gccaccgcaa ataatatgaa acaaaatatc gtgatttcag ttggagtagt gttggtcttg
     5581 ttgaccagcg tcttcttcag cgaatggatg aatatgtcta tcggaatgtt ggttcatgaa
     5641 ggtagtatct tggtggtaat tttcaatggc atgagattaa tgaagtataa gttgaaaggt
     5701 cggaaagaac aaaaagaagt atcagcacct acagagaaag taaaaatatc ttaagaataa
     5761 attagaagag gctgagacaa tagtccatcc ttgaaatgac aaaagcggaa actcagattt
     5821 ttaaatctgg gattttccgc ttttttgagt tcttgaaaaa aaataagagt atagagtatg
     5881 ttctttataa aattaatttt cgtgtaaatt attaaaaatt taataataaa atttaaattc
     5941 ctattaagtt gtaacacatg aaattgctta aaatagtgta tcaaaaacct tgttttatta
     6001 atgttgaatt tatttgaaag gtctacagat taacatatta ttgacaaaac aatatttaaa
     6061 tagttatact tcattcaaac gtctgtttga acgaggtggt gaagttaatg actgcagaag
     6121 tatgtacaac tacttgtata cataaagaaa aagtagctag tgttaaaaat aatttaaaag
     6181 ataaagacct ttcaacttta cttgtattag gaaaatgttt tagcgattct tctaggatta
     6241 aaattttcta tgctttagaa acgtataagg agatgtgcgt ttgtgattta gcagcgatac
     6301 ttaatgctag tattgctaca acgtcacacc atttacgttt tttgaaaaag aacggaatgg
     6361 cgaaatcacg tcaatatgga aaggtagttt attactcttt agcgaatgaa gagattcttt
     6421 ccgctgtgca ggcttttcta aagttgtcag aaaatagttc tatgaaagct tagtttggag
     6481 gtagttattt tgttacaaaa cattttatca gcactcgctg tatatatttc taccagtatt
     6541 gattatttat ttatcttgct gattattttt tctcaaaacc atactaaaaa aggtctccgt
     6601 cagatttttt ttggtcaata tcttggaaca ggaatcttgg tagccataag tttgtttgca
     6661 gcatatgtgc taaattttat tcctcaagat tggatcattg gtcttctggg actaattccg
     6721 atttatttag ggattcgtgt tgcttttgtg ggcgaagagg aggaagaaga aggggaagtc
     6781 gttgagaagc taggatctag aggaacgaat cgtttgtttt ggacagtttc cttaataacg
     6841 attgcttctg gtggcgataa tttagggatt tatattcctt tctttacctc gttatctttt
     6901 tcagaaattg tcacttcttt aatcgtcttt gctatctctg ttgcggttct ttgctatatt
     6961 agttataaat ttgcgaaaat ttcttttgtc tctgaaacac tagaaaaata tgaacgaatc
     7021 attgtaccta tcgtatttat tggattaggg atttttatta tgatagaaaa tggaaccatc
     7081 caaactatat taggtttgta gagatcttat tagtaaagga agcaaacgat gagtgaaaat
     7141 aaaaagtacc atgaatggat attagaagga atcgactgtg caaattgtgc agacaaagta
     7201 gaaagaggcg tcgccaaagt tgcaggtgtt gccaatagta gtgtgaacta tatgacagaa
     7261 accttgagtt tcgaagtgac agaggaaaaa gaatatcttg ttttatccaa tgtgcaacaa
     7321 aaagtaaaaa aattggagcc tgatatcact ttaaaaaata aagtggacgg taggctgatt
     7381 gaaataaatc cggcattaat caagaaaagt aatttaaaag acgataaaaa aaactacgaa
     7441 tggatattag aaggaatcga ttgtgcaaac tgtgctgcca aagtggaaag aggagttgct
     7501 acagttcccg gcgttacaaa cagcagcgtc aattttatga cagagacact gagcttcgag
     7561 gtagcaggtg aaaataaaac tgacgtgttg gctagtgtaa aacaaacagt aggaacttta
     7621 gaacctgacg ttgttctgcg aaaaaaatcg gacggtacat tgattgaaca tggaactgac
     7681 tctaataaaa attcgacttc taacaaatcg atttctgata aagatgagac aaaccaaaag
     7741 cagacgaata gagcttatct ggccagcctt ctcggaaata aaactaaaat tacccttatt
     7801 cgtttaatac taggattagg aatattagcg acaggaatat ttctccctat ggatggacaa
     7861 gcctctcttg ggttgttcat tctggcttat ttaatcaccg gttatgacgt tgtaggacgt
     7921 gccattagaa atattttccg aggtcaagta ttcgacgaga actttctaat gaccattgcg
     7981 acgttaagtg ccttctatat tcaagagtat cccgaagctg tagcagtcat gctattttat
     8041 caagtgggag aagtattcca agatattgct atttcaaaat ctcggcgctc cattgcggac
     8101 ctaatggata ttcgacctga ttatgccaat ttagtcacag gaaacaacgt agaaaaagtt
     8161 gctcctgaag caattaagat tggaaatatt attctcattc gtccgggcga aaaagtgcca
     8221 ttggatggaa aagtagtgga aggtgcttct gcgatggaca cttctgcttt aacaggcgaa
     8281 tccgttccaa gaagcgtgaa gccggaagac actattttga gcggatttat taataaaaac
     8341 ggattgctaa aagtagttgt agaaaagccc ttttcggagt ctactgtgaa gaaaatttta
     8401 gatttggtcc aaaatgctag tggccggaaa gcacctactg aacaattcat taccaaattt
     8461 tctcgctact atactccaat tgtggttata gctgctgcct tactggcaat tgttccgcca
     8521 ttgctagtac caggcgctac ttttaatgaa tggatatata gggccagtat ctttttagtt
     8581 atttcatgcc cttgtgcttt agtcgtttcg attccagttg gtttctttgg tgggattggt
     8641 tctgcttccc gcaaggggat tttagtaaaa gaaagcaatt tcctcgaggg tttgaacgat
     8701 cttaaatacg tggtaatgga caaaacgggt acattgacaa aagggttctg ttgcaaagtt
     8761 ttaaatctac tatcaaataa ggtagaataa tagaaaaaga tagtaggagg aatgacgatg
     8821 aatcatttta aaggaaagca atttcagcag gatgtgatta ttgtagccgt gggatactat
     8881 cttcgttata accttagcta tcgtgaagtt caagaaatct tatatgatcg tggcattaac
     8941 gtttctcata
//
LOCUS       DAZKPE010000089         8842 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000089 DAZKPE010000000
VERSION     DAZKPE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.090"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(334..831)
                     /locus_tag="ACG930_002536"
     CDS             complement(334..831)
                     /locus_tag="ACG930_002536"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFQ0519658.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(871..1680)
                     /locus_tag="ACG930_002537"
     CDS             complement(871..1680)
                     /locus_tag="ACG930_002537"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0519659.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2014..2871
                     /locus_tag="ACG930_002538"
     CDS             2014..2871
                     /locus_tag="ACG930_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFQ0519660.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2864..3766
                     /locus_tag="ACG930_002539"
     CDS             2864..3766
                     /locus_tag="ACG930_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFQ0519661.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3799..4149
                     /locus_tag="ACG930_002540"
     CDS             3799..4149
                     /locus_tag="ACG930_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0519662.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4198..5121
                     /locus_tag="ACG930_002541"
     CDS             4198..5121
                     /locus_tag="ACG930_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFQ0519663.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5199..6092
                     /locus_tag="ACG930_002542"
     CDS             5199..6092
                     /locus_tag="ACG930_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0519664.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6130..6693
                     /gene="amaP"
                     /locus_tag="ACG930_002543"
     CDS             6130..6693
                     /gene="amaP"
                     /locus_tag="ACG930_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0519665.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6707..6895
                     /locus_tag="ACG930_002544"
     CDS             6707..6895
                     /locus_tag="ACG930_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0519666.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            6908..7810
                     /locus_tag="ACG930_002545"
     CDS             6908..7810
                     /locus_tag="ACG930_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0519667.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7842..8084
                     /locus_tag="ACG930_002546"
     CDS             7842..8084
                     /locus_tag="ACG930_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0519668.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8340..8711)
                     /locus_tag="ACG930_002547"
     CDS             complement(8340..8711)
                     /locus_tag="ACG930_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519669.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3081 a         1526 c         1709 g         2526 t
ORIGIN      
        1 aaaaacagct tcttatgttt ttacttggct gttcttatta ctgcagatgc aagcttttga
       61 ataccgttta aggaagaggt tgtgaaatca gcgttttgac ctgagtatta gcttaacaaa
      121 cggaaaaata gttcctcata ttttgccgtt tgttaagcta ataccgaggg tcagctgatt
      181 gaacaccatt taagaaagag gtcgtgagcc tgccgtttca ctctgtgtca taaaaaagcc
      241 aatctacttt gatagaaaaa gcacgtagga ctaaaacagt tctgcgtgct ttttttattg
      301 tgtgttaaat atcgtaaatg aagatagata tttttatgat tcgacgatag agacgttgaa
      361 atctttcaac agctctaaag cggattctcc gtgttttcta ctggagacta acattggatc
      421 aacaaaaaag tctgcttcag gaaaagcact ctgcaggcct atcagattag agagtacaca
      481 caagtttgtt tcaatcccga ctacttcgat ctctttttgt tcttctttgc tttcaaataa
      541 agtttcctgg atttcagcta aagtttcagg tggaatcgta aagtaatact ttttaatcac
      601 tcgttcattt tcttgtggag aaagaagagg gatcaattgc aaatcttctc gttcttcttc
      661 tttgtccttc agttcaactg gtatatcccg tgtgaagaga atatattcat tattttggcg
      721 tgctttagct aatctttgag caatacgttc tgccaattga tctgactctg gaatataaaa
      781 ttcgctgttt ggatcaagaa tatgattttg catatcaata ataactaaca ttttctttcc
      841 tcctacattc atatcgtcat tttattcttt ttaatagaag ttttttaaaa tataagcaac
      901 accagcttct tcattcgtca gtgttacttg gtttgcaatt tcttttactt gtcgctgtgc
      961 attccccatc gcaatactca acccgctgta attcaacata gcaatgtcgt tttcttgatc
     1021 gccaaaagcc atgatgtcac tcgattcgat tccaaggtaa tccgccagaa aaacaagtga
     1081 atgagcttta gtgatacctg taggcgtgat ttctaagaaa tgcggatcag agaatactga
     1141 ttggatacca tctgcttgca gatctctttg tagcttctgt agtttttctt cactcttatc
     1201 tgttaatgct aatttaagat agctaagaga aggatcttcc aacatattta aaatttgatc
     1261 aaaagaatgg ttctgtaaat tgaaatgttc ataataaggg tcatctttga ctagatttga
     1321 ttcatcgaat gtcagctgat catcttgggt ttctcggcta gcaatgatgg atattttcgc
     1381 ttcttgagca tagaagaagg cttttctcag tgtatcgcta tctatttttg aacgtctgag
     1441 aactttcgcc atttttccat ccttcatttc agcaatcagt gaaccattgg aagaaatcaa
     1501 atagccaccg attcctaatt cggaaaaaat atctttagca gaaatgctgt tccttccggt
     1561 agcgacggtt acgattccgc cattttcatc aaatttccga agtgcttgga tattttcttc
     1621 tggtatcttt ccatttcgat caagcaaggt accgtctaaa tcaatcgctg ctagtttcat
     1681 tttatcttcc tactttcttt ttacatatct attttcctgt taccttaaga ttaaatgaga
     1741 atttaaaaaa atgaaactaa cttgctttgt cattatgaat tttttcaaaa aacattctta
     1801 agaaaaaggt ggctatatat agtagttttt ggtcaatacc tttgaataaa aagccatgaa
     1861 aaacgaatag ttagcgctta ccgatgcgtt ttgtgataaa aaaattttaa aatattcaat
     1921 gaaaacaaag catatatttt gctttaaaac caaatgagga atattctaga tgtagaacag
     1981 gttagaaaaa gattagaaaa aggagtgatt ttgatggaga agagatacgg cgtagttcct
     2041 gtggtaactg cttcagacga aaattatgct ccttacttga gcgtgatgat cgcaactgca
     2101 ttagaaaatt gcaataaaac aagacgcata aaattttatg tgattgacga tggtctatca
     2161 gaatatagta aagaaggatt ggaagaaacg gtaaataaat attcaagtaa tgcaagtatc
     2221 caattcctga cagtggaaaa agatatctac gaagacttcc tagtcagtga ccatatcaca
     2281 actaccgctt acttaagaat ttctttacca aacttattag ctaaagagga ttataagaaa
     2341 gtcctttact tagattcaga tgtgttagta ctagacgata tcgtaaaact atatgatgag
     2401 ccgttaaatg gaaaaacaat cggcgctatt atcgatccag gccaagtgaa agctttggaa
     2461 agattaggaa tcgattccga tgacttgtac ttcaattcag gagtgatggt gattgacatt
     2521 gatcaatgga ataaaaaaga aattacagaa aaaactatcc attacctcag tgaaaatggc
     2581 gatcgaatca tctatcacga ccaagatgct ttgaatgctg tactttatga agattgggaa
     2641 caacttcatc caaaatggaa catgcagact tcgctgattt ttgaacgtca tccagcacca
     2701 aatgaaaaat atgaacgtca gtataaagaa ggaaatgaaa aaccttcgat cgttcacttt
     2761 acaggacatg ataaaccttg gaatacgttg aaagatcatc cgtataccaa tttatactta
     2821 aaaaaattag cacacagtac tctaacgaaa gtaggcgaga tcaatgaata aaaaagaaat
     2881 agcagtagtc gcaagttgta acacaaaatt cgtaccacat ttagctgcat tatttgtctc
     2941 agtattagat aattgcaacc cgtctaaatt tgttcggttc tatgtgattg acgatgatat
     3001 cgattttgaa agtaaacagc ttttacgctt ctcagtgaaa aacgcacgaa tgaactcaga
     3061 tgtggaattc ttgaaaatca ataaagaatt ctttacaaat gtggtaatca gcgatcgtat
     3121 tccagaaaca gcttattatc gtattgcgat tccggaattg ttccgcggca cagaagttga
     3181 acgtatctta tatatggatt gcgacatgat cgctttacaa gatatctcta aattatggcg
     3241 tcttgacttc ggtgattcaa tcgtagcagc tgttgaagac gctgggttcc atcaacgact
     3301 ggaaaaaatg aaaatttcag ctaaatcaat gcgttatttc aactcaggtt tgatgctgat
     3361 caatgtgaaa aaatggttag atgaaaatat tacgcaaaaa gtattagatt tcatcgaaca
     3421 taatccagaa aaattacgat tccatgacca agatgcatta aatgctatct tacatgaccg
     3481 ttggttacca cttcatccgc gttggaatgc acaaggctat atcatggcaa aagcaaaaaa
     3541 acatccaaca gcagcaggtg aacgtgaata cgaagaaact cgcaacaatc cttacattat
     3601 ccatttttca ggacatgtga aaccgtggag caaggatttt gaagggccaa cgaagaaata
     3661 ttacgaaaaa tatgcaggga tgacggcttt ccgttgtgta gctaaattcc ctaaatatcc
     3721 aaaatatgca aaagttcaac caaaaacaga tgtagttgtt aaataataga agacaacaac
     3781 tgaagagggg gagtaggaat ggaaattaca atgtctaaaa atgcagtaga gacgttaatt
     3841 gaaaaggttg gggaaaatac aaaaatcgca ctcgcgctta tcaatgattc cgatccattt
     3901 ctaagggaca aaggtgcttt tgcaaaaggc agcttttttc aaatcattcc ttttgtttcg
     3961 gaatttggag aatatgcgac taaaatcgag catccattat tggacatcta tacatctaaa
     4021 ttagagcaaa attatttcgg taaacgattg aacatggact tcaacaaaca gcttgacagc
     4081 ttttcattag aaaatgaaat cgcagtactc gattataata tcaaattaaa gaactgcttc
     4141 ttcagctaat agtttcgaga aagtccaaaa aggaggtata cattgagata ctactttgtg
     4201 gatgaagaaa agaatgtaat agaaacagat gaaaaaaaat ataattggct cgtacttgat
     4261 agtgcaaagc ccgaagagat tgagcaagca atcgaagaat tcgagcttcc tgatgatatt
     4321 ttcgtaggaa ccgaatatcc ggaagaagtt tctcggatgg agcgccttta tgagacgaaa
     4381 ctagagcatc cattttcttt ggtagtgatt aatctagatc agtcagataa tcgtatcgaa
     4441 aaaaaattaa cgccaatatc ttttgtactt tccgataatc tcttgattac ttgtatcgat
     4501 agaaaaaccg aatttgtgga tcggctgctg acaaagcatg gaaatcattt aaactcgttt
     4561 gaaaagatca tcacgtatac attattagat atttacaccc attacgtgaa agaactaaga
     4621 gagatgaaaa agcgaattga cgctttggat aaagcagctc gtaaaacaac ggaaaatgaa
     4681 gaactgtata aacaggcaga tcttgaaaga gacatcgtat atatcgatca taccttaaga
     4741 gatcaacggg aaacaatgga tcaattatgg aattctgaaa ctttcatcaa acgtttagac
     4801 gatgaacagc tactctatga tgtccatttg agacagcgac aaacagaaaa aatgatcgag
     4861 atctatcgag atttattaga gagtattggt gatctattca acgggatgat ggacaataat
     4921 ctaaatcata tcatgaaata tctagattca gctgcattaa tcatttccgt tccggcgttg
     4981 ttcgcaggga tttggggaat gaatacagga ggattaccgg gtaaaagttc tgctctaggc
     5041 tttatactcg tagtctttgg ctctttgata gcagcagtag ttttaggtta ccatttatac
     5101 cggaaagatt atacaaatta aagaatctat ttaaaacagg tatcaaacaa agaaatttgt
     5161 tttggcaata caatttaaaa actaggagga atacagcaat gacagaacca aaattaatcg
     5221 acccgcgaaa cttgtaccat acggagaaat ttcctaaaca agatcaggat acaccagctt
     5281 tacagcagaa tatgattcct gttcctgatt gtggagaaga atcctatgaa ggcaataatc
     5341 aactagaaaa ccgccgtgta ctaatcactg gtggagattc agggatcggt cgtgcagcag
     5401 cgattgcatt tgctagagaa ggggcagata tcgctcttca attcttccca ggagaagaaa
     5461 aagatgcaga ggaagtagca aaatacgtga aagttgcagg acgtaagatt gtcttactac
     5521 cttttgatct tcgtgacgaa caagcaccta aagaaatcat agataaagcc gtgagtgaac
     5581 ttggcgggct agatacgatg gtactaaacg caggacagca aatttcttgt cagtctattg
     5641 ctgagttacc acttgagcaa gtcaaagaca catttatgat aaacatcatc gctatgtttg
     5701 ctttagtgaa agaagctgtt ccgcatatcc cagcaggagg agcaatcgta acaacaactt
     5761 ctgttcaagc attcaatcca agcgaacatt tattagatta cgcagcaaca aaagcttcaa
     5821 tcgctaactt tacgatcggt ttagcaaaac agcttgcacc taaaggaatc cgtgtaaatg
     5881 gtgtagcacc tggtccaatc tggacaccat tacaactaga cgaaggacaa ccttctgatt
     5941 cgatccctga atttggtcag caaagtttac tagaacgtgc aggtcagcca ggagaattag
     6001 caccagttta tgttttctta gcatcgaata aagcaagtta tgttacagcc caaatttacg
     6061 gagtaactgg tggagaagcg atcaacttat aagaagttga tcgtttcacc cctatgagga
     6121 ggtgcgaaaa tgaataaagg tgtaaaaacg atcggagtga tcggaacatt acttttgcta
     6181 tctgtgcttt tgtttgcgat actattaagt gcaacctatc cattgccttt tcagctagag
     6241 aagtttcgat tcttttccat cactaattca tacgtgcaac aatatgtatt ttggcttgcc
     6301 gttgcatttg ctattttgac aattatcacg ttacttgttt tcctgtttta tccaaaaaca
     6361 atcggaaact ttctactgaa acatggtgat ggggagttga cgttggataa aaaagcaatt
     6421 gaaggaatgg ttcgttctca cttgcatgaa gatgaattca tccattcacc aaaagtaaat
     6481 gtcaaagcaa cgaaaaacaa gatcgccgtc aatgtaaaag gggagttgaa acgaacttca
     6541 gcactcattg gtaaaacagg aacattgatg aaagaaatcg aaaatgaagt acaacacata
     6601 ttgggaacaa aagagccagt gaaagtatcg gtgaaataca caggctttga agaaccagct
     6661 aaacgaagca atgaccgcaa acgagtagaa taggggggga ccaaaaatga aagaactatt
     6721 ttcgacatac aagctcccta tcatctttgg ggtacttgga ttgatattag ccgttttatg
     6781 gatcaccgtg ggctttttca agaccttatt gatcttgatc atggcagcga tcggcgtcgc
     6841 tatcggtttt tatctgaaac aaacgaaaat cttagatcac tattttaaat cttaggagga
     6901 aacatccatg aataacaata acaaaaataa taacaataaa atgaacaacc aaaaaccagt
     6961 gtctgcacat ccagacccaa cgacaccaaa ccaatcaaat ggtgtgaacg atgaaaagaa
     7021 caaaacagca ccagtatctg cacatccaga tccagtagtc cctaacgttc aacaaggagt
     7081 agaagagaag aaacatgatg cagaaaagca tgcacctcat catccaggaa ctccagaatc
     7141 taaagttcca gaacaacatg atgcaatcga tccttctaaa cctgtggaag agcaaaaaca
     7201 tccttctgac catgcgaaag cacaagaaaa acttagttct gaccacacaa acggacaagg
     7261 aaaacttggt tctgatcata caaataacca aggaaagcat gattctgaac aggaagattc
     7321 aatgcgcggt gagctgaatt atgaagataa agttgtgcaa aaaatcatcg gaatcgcaat
     7381 tgaacaagta gacggtttat tatctgcaaa cggtggtttc ttctctaatg tggcaggaaa
     7441 acttgtgaat acagataatg taacggctgg gatcgaaaca gaagtcggta aaaaacaagt
     7501 agcagttgat atggatgtca ttgtggaata tggcaaagat atcgaaaaaa tctttgaaga
     7561 aatgcaagaa gtaatcggca aagaagtaaa aaatatgaca catttagaag tgatcgaagt
     7621 caacgctaac gtagtggaca tcaaaacaaa agaagaattt gaaaaagatc aagaaacggt
     7681 gcaagacaaa gtaactgacg cagcgaaaaa aaccggtgaa tttgcttcga atcaaacaga
     7741 taaagtaaaa tcagcagctg gaagcggcgc acaaaaagta aaagaaaata cagaaccacg
     7801 ggttcagtaa taaggaagta aaacattagg aggaacgaaa catgggattt atttggtcac
     7861 ttatcgtcgg aggaattatc ggagcaattg caggagcaat cacgaataaa ggttcttcga
     7921 tggggattat tgcaaatgtc gtagcaggtt tagttggatc agcacttggt caagcattat
     7981 taggttcttg gggaccaagt attgcaggaa tggcaatcgt gccatcattg attggtgcca
     8041 tcattttagt actaatcgta tcattctttg ctcgaaaact gtaaaaagac ttttaaaaag
     8101 aggtcgtgaa aaagctgttc ttcatcaagt aataagaaca gccaaacaaa aatagcttct
     8161 catatttttc atttggttgg gcatattatc gaagatgcaa gcttttgaac actgtttata
     8221 cggaataaga ggctgtgaca agacttttgt cacagcctct tatttatgcg ggcaaattcc
     8281 caattagatt tttaaaagtt tttccttaaa tgtgtcttta ttgatacaga gaagcttctt
     8341 taataaaaca atgcctccct aaattttctt gagataggaa aggtgaacat acaaaataat
     8401 acgaccactt tgaaaaccca gatgatccac aaatggatcg tatgatactg atgaagtaaa
     8461 aagcaatgga tcagaaactc aaagagattg aaaaagacaa ggaagaaata atatctcttt
     8521 tttactcttg tctgttttag ccaataatag ctcgtaaagt aatctagaca aacaaataga
     8581 agtaaacaaa gtttcgtaag agcagcaatc gtatcatgtt gctctgctag acgattgacg
     8641 agcaggaaaa atgttggtaa tggaatatag atcacgagta atgaaagaaa aaagtaaaca
     8701 ataaatggca tactattcct cctaattgtg tgagttcgcc ctcattttaa aataacgata
     8761 tttgtttgtg aagctttttc gtgtcgtaac aaatgttatc taatgtattt ttaaataaat
     8821 aatcattatt atcaaaataa tg
//
LOCUS       DAZKPE010000090         8838 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000090 DAZKPE010000000
VERSION     DAZKPE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.091"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            107..754
                     /locus_tag="ACG930_002548"
     CDS             107..754
                     /locus_tag="ACG930_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519670.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(847..3126)
                     /gene="helD"
                     /locus_tag="ACG930_002549"
     CDS             complement(847..3126)
                     /gene="helD"
                     /locus_tag="ACG930_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFQ0519671.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            3404..5227
                     /locus_tag="ACG930_002550"
     CDS             3404..5227
                     /locus_tag="ACG930_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFQ0519672.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5274..5453
                     /locus_tag="ACG930_002551"
     CDS             5274..5453
                     /locus_tag="ACG930_002551"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFQ0519673.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            5790..7730
                     /gene="thrS"
                     /locus_tag="ACG930_002552"
     CDS             5790..7730
                     /gene="thrS"
                     /locus_tag="ACG930_002552"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFQ0519674.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            7954..8802
                     /locus_tag="ACG930_002553"
     CDS             7954..8802
                     /locus_tag="ACG930_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0519675.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
BASE COUNT         2782 a         1571 c         1879 g         2606 t
ORIGIN      
        1 ttttttgtgt gatttatttt cttttctaat tcaacctgtg gtatgatgag agcataagta
       61 tcatgtgaaa tgatatgaag tatgtggaag atggacgggg aagaatatgg aagcaaaaat
      121 cactttagaa ccttttgaac gtatcttaag cggttaccgc aaagtagaag agttagctgt
      181 gaacgtaact gattgttcaa aattagcgca aaaatacgca agattcggcg ttgaaggcta
      241 tcgattagga aactatgtcg gtacagggta tctgaaccgt tatttagagt gtatggtgga
      301 ccgcgcacca atgctgattt atagacaaaa ttatctgatt ccgctgcttt ttcgtcgttc
      361 tgattcagcc tttcggttat ttgaagaaga gtatcggatg gaggctttct ttctactatt
      421 agagtggagc ttgaaacatc gtcctgaaaa aattcttatc gaaagaaatg agaagataga
      481 cacgaaaaaa aataaagtga tcgatagtgc atacctagca tttcgtgtat cagagatttt
      541 ggattgtggc ggctatccaa tcagcaattt ccaatcaatt gaccaattca ttgaatggaa
      601 tcgaatttac cgattgatcg acaatggcgg gattggccgt catagcaagg tatttgaccc
      661 agaatatcca gaaaacatgg aagaactgaa aatgattatt tcgcttgtca aattaaaata
      721 tcctgaaaca gatttggatt tatatataga ataaatgacc ttaaatgatt gaattacttt
      781 ttctgcaatt attattgtaa ataaaaagac aactgctaac attaatgata gcagttgtct
      841 ttttacttac agtacttttt tctcataaga tgaaatatcc atattgttta acaaaggact
      901 ttcattattg gaggtaaaaa gggtcaattc atgcatcgca cgtgtacaca tggtgtaaag
      961 gatcaatttg tcttgctgag aagaaaaatg ttctgcatct acatcccaca agaaaactcg
     1021 gtcaaactcc agaccttttg ctaaaaaggc tggaagtaaa ataatggaac gcttcataaa
     1081 gtcactctca tttaaaatca gctggacttg ttgtttcaac tcgtctggca gttgagcata
     1141 aagagcttcg cattcttctt gtgttttagc tatgattgct gtacgccaat accgggcttt
     1201 tccctgagtc gttcgaatgg tatctgctaa ccaattcaat ttgatatcat ctgttgttcc
     1261 ttggatgagc aaaggaaggt ctccttttct tgctgttgtt tctacttgat gttctttcac
     1321 aataaaatga ttagcaaaat cagtgatttc ttttgtggag cgatagcttg tcgttaattg
     1381 gaaacgagtg acttcacggt ccacgaaaag gtcttccaat gatccaacga tcgtttcatt
     1441 tccaaagaca ttttgattta gatctccaca gaaagtcaaa tttgcttttg ggaacaaggc
     1501 ttgcagcaat gccacttgtg atggtgcgaa atcctgcatt tcatcaataa agatatagcg
     1561 agctttgtgt gtaaccgtca ctggatatgt tcggcgcatc agtaaaaaga atagtacagc
     1621 atcctcttga cgcaattctc tttgacgcaa gtgtgtacga acagttgtca aatgttcctg
     1681 ccacctggtc tcgctgattt tatgtcgtgt tagaagagaa agtggcacag tttgtagaaa
     1741 gtggagatat tgtttcgtta tattgacaaa ttgataattc atgatccctc gatggattcg
     1801 acggaatctt ttacgtacga tttggttggc cagtttttta cgtaatgaac gctccttttg
     1861 ttctgtatat tcaagatttg gatctgttgc gtatagttct tggagctgtt cttccgccag
     1921 atctttgacc cattgctgac gtgtttcgtc tttttgcaga ccgcctaatt ttttcaggag
     1981 cttcgtttgt aatagagaaa gtctatgatg taaaggtaat tgttcatttg tttctttata
     2041 ccattggcga atcgattcct ttgataggat cgtacggcca tttattttca tatcacggaa
     2101 caagggaccg tagtttgtga tgccttggat atagcgatca atctgatcga ctaaggtcaa
     2161 tccgcttttc atcacttgta tcggatcttt ttcccctagc aaaaaaccac tttcttgttg
     2221 ctgttcatct agtaaagaaa actctggcag cagctgcacc aaataatttt tgaatgtctg
     2281 tgtaggcacg ccgctttcac ctaatgaagg caatacagtc gagatgtaat cagaaaacaa
     2341 atggttgggt gaaaatagaa gaacgttttc agcctcgagc cacttgcgat tatgatacaa
     2401 cagaaaagca atacgttgaa gcaaagcgga tgtctttcca cttccggcga ttccttcaat
     2461 cagcattact ttacttgttg tgtcccgaat gattgcattt tgtgcttttt gtatcgtaga
     2521 gacgatgttt ttcatatggt tgcttgatga ttcatccaat atctctagca aaaagtcatc
     2581 attgattact tccgacgtat ctaccataga taaaatacgt ccttcttgga ttttaaattg
     2641 tcgtttcaac tgcagatcga catctattct atctgtttca gtttcataaa atgcgggacc
     2701 aatctcacct tcataataaa gattggcaat tggtgcgcgc cagtcaataa cgattgtttc
     2761 ttctgccaga tctcttaaag aagcgatacc tagatataat gtttctgttt cacggtcttc
     2821 tttaaagtcg atacgggcaa aataaggact atctttcatg acagacaacg tttgcaggcg
     2881 tttttgctgt gcttcaagag tatggtattt caaaagcaat tcctgctcat gttggcgata
     2941 ttcaacagca gattcataaa aagcttcatt ggaaccagct cgaatcttgt gattagctgt
     3001 gtcttttgtc gaatgattca tttcctgagt caattcttgt tgttttgtat ccagcatatt
     3061 ttgttcgatc tggattagtt cgatcgtttc atccacgtgc gtttgttcta gttgtttctc
     3121 attcatcgca tgtttgctcc ttccgccgta aataacgaat taaaagtata gcatagtttt
     3181 tcgaaaaaag gtacttttta actgatgaat cgaaaaagta atccttgctg aatatttttg
     3241 tttgtagaac tgatgaattt tggaaacgct gatagtgata gttgttttca attaaggcct
     3301 attgttttaa aaagtgctag tcaaggacta tgcttaagat gaaagaggca gctggaaatt
     3361 tattactaac ctctctaagt cacataaaag aggagaaaaa acaatgacac atttcaaaaa
     3421 atttttactt actttgctta ttggtgggat agctttatta agtgaatttg tttttcacca
     3481 gccggccctt gcatttgcga ttgtcgcatt tactggaggg attctcgcct tcttgatgtt
     3541 tttggaaatg atcaagacgt tacgttcagg aagatatggc gtagatgtat tagcgattac
     3601 cgcaatcctt gcaacattag ccgtcaaaga atactgggct agtttgatga tattgatcat
     3661 gcttacgggc ggagatagtc tagaggatta cgcgaataaa cgagcgggta aagaactgca
     3721 gtctttgtta gataacaccc caagaattgc ccatcgattc aaagaaggaa aattgcagga
     3781 tatagtaatc gatgaaataa atattgatga ccagttacta gtcaagcctg gcgaacttgt
     3841 acccgcagat ggtcgagtga ccaaaggaga atcttcggtc gatgaatctt ctttgacagg
     3901 tgagtcccgc ccggaaacca agaaacctgg agatcagatt atgtcagggt ctttaaatgg
     3961 agacggatcg atccaaatga tcgctgaaaa acgtgccgca gacagccagt atcaaatgat
     4021 tattaaacta gtcgaagaat caaaagaaaa gcctgcccga tttgtccgtt tagctgatcg
     4081 ttatgcagtc cctttcacgt tgattgctta tttgatcggt ggtatttctt ggtggttctc
     4141 aaaagaccct ttacgatttg ctgaggtact ggtagtggca tcaccttgtc cactgattct
     4201 agctgcgccc attgctttag ttgcaggaat gagccgttca agtaaaaacg ggatcgttgt
     4261 aaaaactgga acaacgattg aaaagctcgc acgtacaaaa acgattgctt ttgataaaac
     4321 aggaacgctt accaaaggga tattggaagt agaggcgatt cagccagtca atggaataaa
     4381 aaaagaagag ctacttctgt atgcagctag tgcagaacag gaatctagcc atatcttagc
     4441 tcgttcgtta gtgaacaacg tgaaaaacag ccaactgtat cctgttagtc aactgaaaga
     4501 agtgaccggt caaggaatcc aagcagtagt caataatcat gaagtaaaga ttggacgtgc
     4561 ctcttttgtt tcagctgaag aaatagaaac gtccaataca gcaatctatg taacaattga
     4621 tcgatctttt gcaggaacga tcctattttc ggatcagatt cgcccagaag cagcaaagac
     4681 aatcaaggag ctaagaaaac ttgatgtgaa aaatttgatg atgatcaccg gggatggatc
     4741 tgccattgct caaacgattg cagaaaaagt ccaattagat tctgtacatg cccgtagctt
     4801 gcctcaagat aaactgacca ttttagaaag tatccctaaa gatcaaagac ctgttgcgat
     4861 ggtaggagac ggcgtgaatg acgcaccagc acttgctgct gcagatatcg gtattgcaat
     4921 gggggctcat ggttctacag ctgctagtga aagtgcagat gcggtcatct tgaaagatga
     4981 tctcttgcgt gtagcaaaag cagtagtgat ttcaagagat acgatgagaa tagcgaaaca
     5041 gtctgtactg attggcatct ttatttgtat ttttttgatg ttaattgcaa gtacgggact
     5101 aatccccgca ttattcggag ctgttttgca agaagtcgtg gatacggtct ctattttgag
     5161 tgccttgaga gcaaaaaaag atccagccat ttttcctgat tcagtaccca agacaaacat
     5221 agtatgatag aatcgagttg aaaaaagaac gatcagaaag aggagagagc attatgccat
     5281 tcgtacatgt cgaattagta gaaggtcgca gtccggaaca attagaaaat atgatgaaag
     5341 atatcacgga agctgttcat aaaaacacgc aggcaccaaa agaacacatc catgtcatca
     5401 tcaatgagat gaaaaaagga acatacggtg taaatgggga atggaaaaaa taagtttagt
     5461 ttcccacttg atttttctat ttattagtgg ttaaataaac acataattga ttgatgagaa
     5521 agccaactga atttgagagt cttcgataag agaggaaaag ctaggctgaa acttttccag
     5581 gagaaaacca aaggatgacc actttcgaaa cccttgttga agcaagggcg gtcggaccgt
     5641 tacaacgctt gaggaacgca tttgcgtttg aacattaggt ggaaccacga acttttcgtc
     5701 ctagtatctc ttttcaagag atgctaggat ttttttgttt ttcagcttga tgatctgatc
     5761 aatcaaaaca tttcaaggag gaaactatta tgataaaaat tacttttcca gatggtgcag
     5821 tcaaagaatt tgagtctgga acaacaacat tggcaattgc tgaaagcatt tcaaaaagct
     5881 tagcaaaaaa agctttagct ggtaaagtga acggaaaact cgttgatttg actcgtccaa
     5941 tcgaggaaga tgcaagtatt gagatcatca caccagacca tgaagatgca cttggcttag
     6001 tccgtcattc agcagctcat ttgatggccc aagccatgcg tcgcctctat ccaaatatcc
     6061 actttggcgt tggaccagct atcgattcag ggttttacta cgatacagat aatggacaaa
     6121 accaagtaac tgcagaagat ttgccggcaa tcgaagcaga aatgatgaaa atcgtcaaag
     6181 aaaatctgcc gatcgaacgc cgtgttcttt caaaacagga agcattagaa atttttgcaa
     6241 gtgatccgta caaagtagaa ctgattagtg aattgccaga agaagaagtg attactgctt
     6301 atcaacaagg cgaattcatc gatttgtgtc gtggaccaca tgttccatcc actggccgta
     6361 tacaagtatt taaattatta tcagtggcag gtgcttattg gcgtggaaac tcaaacaatc
     6421 aaatgatgca acgtgtatac gggacagcct tttttgacaa gaaagctttg aaagaatata
     6481 tccgtctccg tgaagaagca aaagaaagag accatcgtaa actaggaaaa gaacttgact
     6541 tgttcatggt ttccccagaa gtaggttctg gtttgccatt ctggcttcca aaaggggcaa
     6601 caatccgacg cacgatcgaa cgttatatcg tagacaaaga agttagtcta ggttaccaac
     6661 atgtatatac accaataatg ggagatgttg agttgtacaa aacatctgga cactgggatc
     6721 attatcaaga agacatgttc ccgccaatgg atatgggaga tggcgaaatg cttgttcttc
     6781 gcccaatgaa ctgccctcat cacatgatgg tctacaaaaa cacgatccat tcttatcgtg
     6841 aattaccaat tcgtatcgct gaattaggaa tgatgcatcg ctatgaaaaa tcaggtgctt
     6901 tgtcaggttt acaacgtgta cgagaaatga cgttgaatga tggtcataca tttgttcgtc
     6961 ctgatcaaat caaagatgaa tttaaacgta cgcttgaatt gatggtggca gtatatgctg
     7021 acttcaatat tacagattat cgtttccgct tgagctatcg cgatccaaac aatacagata
     7081 aatattttga tgatgacgca atgtgggaaa aagcccaagc aatgctgaaa gccgctatgg
     7141 atgaattaga actagattac tttgaagcag aaggcgaggc agccttttac ggaccaaaac
     7201 tagatgttca agtcaaaaca gctcttggta cagaagaaac attatcaact atacaattag
     7261 acttcttatt gccagagcgc tttgatttga catatgttgg agaagacggg gaaaatacgc
     7321 atcgtccagt agttatccac cgcggaattg tttctacaat ggaacgtttt gtcgcttatt
     7381 taacagaagt atacaaaggc gcttttccaa catggttggc acctatacaa gcaacaatca
     7441 tccctgtttc tgttgatgca catggcgatt atgcttatga aatcaaagaa cgtttgcaaa
     7501 tgaaggggtt gcgtgtagaa gttgatgatc gtaatgaaaa aatgggctat aagatacgtg
     7561 cctctcaaac acaaaagatc ccttaccaat tagttgttgg agacaaggaa ttggaagatg
     7621 caacagtgaa cgtacgtcgt tatggaagta aagaaacagc tgtagaagat ttgaatatct
     7681 ttattgatgc tatggaagca gaagtcaaaa attacagcag agaaaactaa taggtaaatt
     7741 tcctgtaaaa aagtagtaga tagaaagcaa tccgaacaat agataacagg tattcctcaa
     7801 agacacagat gctcaataga atctgtggga ttgatgggat aagatattct gttgggcgga
     7861 ttgttttttt gttttttatc cagtatacga ccgtgaataa gggtctgata tggtatactt
     7921 acatagacta tcattaaaag ggtggaggaa cttatgagcg taattagtcg tattgaaagt
     7981 atgatggaag attattcttc agcagaaaaa aagttggcca actacattat cggtaatatt
     8041 gagaaggtcc ctacaatgac agctaatgaa ttagcagaag cttccgggtt gagtgcgccg
     8101 acagttgtac gtttttccaa aaaaatcggt tttcaaagtc tgacggactt caaaatcacg
     8161 atttcaacag aactacagac tggaatcgat gaaggtttta gtgatataga agcaaatgag
     8221 tccttttact ctatcaaaaa caaacttggt aacaatgcac aagtagcgat aaaagaaaca
     8281 gtagatattc tagaagaaga aacgatccaa aaagtcgtag agtgtttgga atcggcagag
     8341 actgtttttt tatatggggt tggcgcctct tctttagtag tagaagatat tctgcaaaaa
     8401 tggtctcgtg tcggtaagcc aatcattttt gaaaaagata tccacgtctt gctcccgcaa
     8461 cttgtcagca atgagaaaaa gaaagtgctt tggcttgttt caaactcagg tagaagtgca
     8521 gatgtagtcg cattagccga gctggcgaaa agcatgaata tcgaaatcat tgcgttgacg
     8581 caatttggaa ataacccgct tagcaagata gccgatgtac tcgtacaaac atctagacca
     8641 aaagaaatca cgaatcgaag tgcggcaact aattcacttt tggcccaatt tgctacgatc
     8701 gatatcattt tttatttcta tatggctaaa aacgaaaagc ttagcgaaaa agtgaaaaaa
     8761 acacgagaag caatccaaga atattttatg gattcgaaat aaaaacctta ctatttttta
     8821 tataagtttt ttagaata
//
LOCUS       DAZKPE010000091         8593 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000091 DAZKPE010000000
VERSION     DAZKPE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.092"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..1518)
                     /locus_tag="ACG930_002554"
     CDS             complement(52..1518)
                     /locus_tag="ACG930_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFQ0519676.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1905..2501
                     /locus_tag="ACG930_002555"
     CDS             1905..2501
                     /locus_tag="ACG930_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0519677.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2559..3041)
                     /locus_tag="ACG930_002556"
     CDS             complement(2559..3041)
                     /locus_tag="ACG930_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519678.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3147..3344)
                     /locus_tag="ACG930_002557"
     CDS             complement(3147..3344)
                     /locus_tag="ACG930_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519679.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3639..4397
                     /locus_tag="ACG930_002558"
     CDS             3639..4397
                     /locus_tag="ACG930_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFQ0519680.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4457..4885
                     /locus_tag="ACG930_002559"
     CDS             4457..4885
                     /locus_tag="ACG930_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519681.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4931..5003
                     /locus_tag="ACG930_002560"
     tRNA            4931..5003
                     /locus_tag="ACG930_002560"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4964..4966,aa:Gln,seq:ctg)
     gene            complement(5153..5524)
                     /locus_tag="ACG930_002561"
     CDS             complement(5153..5524)
                     /locus_tag="ACG930_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFQ0519682.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5739..5924
                     /locus_tag="ACG930_002562"
     CDS             5739..5924
                     /locus_tag="ACG930_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519683.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6007..6195)
                     /locus_tag="ACG930_002563"
     CDS             complement(6007..6195)
                     /locus_tag="ACG930_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519684.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6219..6482)
                     /locus_tag="ACG930_002564"
     CDS             complement(6219..6482)
                     /locus_tag="ACG930_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519685.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6640..6897
                     /locus_tag="ACG930_002565"
     CDS             6640..6897
                     /locus_tag="ACG930_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFQ0519686.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6968..7159)
                     /locus_tag="ACG930_002566"
     CDS             complement(6968..7159)
                     /locus_tag="ACG930_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519687.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7300..7620)
                     /locus_tag="ACG930_002567"
     CDS             complement(7300..7620)
                     /locus_tag="ACG930_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519688.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7643..8077)
                     /locus_tag="ACG930_002568"
     CDS             complement(7643..8077)
                     /locus_tag="ACG930_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFQ0519689.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8412..>8593
                     /locus_tag="ACG930_002569"
     CDS             8412..>8593
                     /locus_tag="ACG930_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFQ0519690.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2726 a         1695 c         1360 g         2812 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaaaaga agatagagat ttaataatta
     1681 tatatcagct gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata
     1741 actaagaaaa tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta
     1801 ttttttgtga gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat
     1861 caattaaaaa aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg
     1921 acactttgaa aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg
     1981 aagaattaac aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc
     2041 aatcaacacg cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg
     2101 aagaagcact tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag
     2161 ctggtttcaa aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag
     2221 gtctacaaga acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa
     2281 acggaatcgc aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact
     2341 tgcaacatta caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa
     2401 actggaaact acgttcgcaa ttagtattcg gttcaccaga aacaccggct gaggaaaaag
     2461 aatacatgaa cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa
     2521 cagaggttgt gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata
     2581 tcaatctctg cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat
     2641 gcagaaaatt tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt
     2701 ttagaacctt ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt
     2761 ttgtcaaagc tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa
     2821 ctaataaaaa tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg
     2881 atgagtgtat accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga
     2941 tttcgcacag tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca
     3001 acaacgaata aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt
     3061 tcttctccag aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca
     3121 gcacgccgca cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg
     3181 cttgcttttt catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg
     3241 gcgcagtttg tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt
     3301 ttgcatgcat attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac
     3361 tgctggaact tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt
     3421 ttatttacag ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa
     3481 ttaaaacagc tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa
     3541 aactaattat ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta
     3601 taataggaaa gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa
     3661 aactattgtt tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac
     3721 atatccattc tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga
     3781 aaaagacaaa agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt
     3841 ctccttcttt agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg
     3901 gttatgaaac aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg
     3961 cagatgggac tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact
     4021 gggctatggt cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg
     4081 attatcacac ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta
     4141 aaggaaatcc tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt
     4201 ttatgacttg gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg
     4261 tagtcactgg atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc
     4321 gagcagtacc gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa
     4381 ctttggagaa aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt
     4441 gaagggagcg tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc
     4501 gattattttt gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg
     4561 gaacgagcgt cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc
     4621 tcttgtttat tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat
     4681 tgctcgaaca gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat
     4741 tatgaatgaa cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact
     4801 gattgccctt cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca
     4861 acaactatcc gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt
     4921 attgaataaa tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt
     4981 aggttcgaac cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa
     5041 agaacaatct ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca
     5101 taattaaatt atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa
     5161 taattgctaa tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt
     5221 gtgctccttt attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa
     5281 attcaaccgt tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac
     5341 catattcatt tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta
     5401 atggatttag ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt
     5461 tcagtccaaa tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt
     5521 tcatctttct acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc
     5581 gtcccaagtt ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa
     5641 aaatgatcgt tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca
     5701 tgtaaaaaat catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc
     5761 aaaaagtcaa ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag
     5821 aacataaaga acaattagga ccttataaag agaaagccca aaatctttta aaagatgtaa
     5881 atatcgacag tgtcaaaaac aaatttaaaa atctattcaa ataagtaaaa ctttcacttt
     5941 tgtaaaatca aaggaggaca atgctgctgc atcgtcctcc tttggttctt ttctgaatac
     6001 ttcatactaa aataaacgtg tcggatcgta atgataagtc acattgccgt tcagtgaggc
     6061 ttttcccacc acatatttac gattctccaa cttcagccac gcttctcgaa aagccattaa
     6121 ttcttctctt tttacatcaa tcttttcgat ttttccatcg atcaaatctt gaataagttg
     6181 ttcatatgga ttcatttttt tcctccatct gctgtcaatc aataagttgt aaaaataggt
     6241 tcatatgctt ttttggtatc tagatcttct ctgactttga ctgtcgtata aataattttt
     6301 tctactggga tactataata acttccttca ccattattga atcggtgaac gtctttcttt
     6361 gctaaaatac catttatttt attcgtcagt acacgttgtt cgacactgtt acttacaaca
     6421 tagtaaatca cccgaatatt attgatcaaa tgcaaatcga tttctaacac tacatgatcc
     6481 atgaaaatcc cactccttct ttcactttga ttatagcaag tttctcctct aatttcaaaa
     6541 tcgatacaga ttttaccgga taaatccaca aaactgcttg cgccatttcg cacaaagtgt
     6601 tattttgtat catggacttt atttatcgga ggcaatagta tgatcgcgat cggtcaattt
     6661 gttttttata ttcctttttt tattatgata agcattcttt tctattacat aaaatggaca
     6721 aaaaagaagt tttcagtttt actggcctct ttacctgctg tatattttac ttatcaaatt
     6781 ttttctttta ggcattggga aacaacgtct gtattaataa cacacatcat cgaattgacg
     6841 ctttcagtaa tttttcttat tatttggatc tattttttat ataagaatca gaattgaatc
     6901 cctcgcatgt ttaaaaagaa aacgattaaa gatgcagcaa atttctgccg atctttaatc
     6961 gttttttcta ttctgttata ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt
     7021 ttaattctat aaattcttgt gcgatcgggt acttttcttc caaattttct ttgttctttt
     7081 cgatcaggct tttcgcttct tcatattttt tatctgcaca tagtgctttt acttcctgta
     7141 atacttttcc tgcttccatt tgcctcaccc tcttgccatt ttattgcttt aagttttatt
     7201 taagttatac gcattattct agtttcatcc caaataacct tttttcattt ttactcctcg
     7261 aactaatcag ttttctaaag gctgattggt tcgtcttttt tatttttcct ccatttcatt
     7321 ctgctcttct gttaatttat ctaatgcttt gattgatgct gcggctcttg cataatcata
     7381 gctgtataat tccataaatt tatcaggcag aacaaaccac gctggatgat aaccgttagc
     7441 tgtgacaggg aatcctttat cttgttggtt atctccatcc catctcagag caacaccttt
     7501 ttttcctttc cactttacta aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc
     7561 aataattgct aaaatttcta ttttttcttt tggcgcacgg acttcttgag gacgaaccat
     7621 tttctattcc tcccttatct cattacttca cgaccaacac actgcaaggg gcatgtgata
     7681 cgacataaga agcggtcgat ccaactaatg cttgttgtat agcacctttt cctgtcgctc
     7741 ccataacgat caaatcaata ttttcttgtc cagggatgac attggcaatc aaatttcttg
     7801 gatctccagt ttcaactatt gcgtggatct cagcaatgcc gtactctttg gcatcattga
     7861 tttttttcag catggctact tctgttcttt gtttttcatc tgcatagatt tttgaaaagg
     7921 cataggcact atgggtcagc tcaactttgt tgatgattga cacgataaat aagtgggctt
     7981 cattgtcctt tgctaagtca agggcttcag cgaacgcttt gatcgattgt cttgatccgt
     8041 caactgctac catgatgttc tggtatcttt tactcattgg aaccgcctcc tttttctttt
     8101 attgtaacat ctcaagcaaa aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa
     8161 caaaagcaat ttctttcaag ttatttatac atttcttttc tcatcagaac acctgttcta
     8221 atcccattat ttctgcatta tgtgaaattc ctcatcattt ttcacatcga gcgaacatca
     8281 ttctgttaca aaaaacgtgg atttgtcata aattgtcatg cttcttttac ctatgaaata
     8341 ttttcacgtg ttaaagtatt cctcgttgaa cacaacaaat aaaacttttt aacgaataaa
     8401 ggagattttt catgacatca cttaaaactt tactttttgg aacaactttg gctgccggcg
     8461 ctgcattctt catgggaacg actgctcatg cggacgaagc ttataccgtt caatcaggtg
     8521 atactctatc aacgatttct caaaaatacg ttggtgataa ctccttgatc aatgccattg
     8581 cagaatcaaa ttc
//
LOCUS       DAZKPE010000092         8504 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000092 DAZKPE010000000
VERSION     DAZKPE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.093"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..330
                     /locus_tag="ACG930_002570"
     CDS             <1..330
                     /locus_tag="ACG930_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0519691.1"
                     /translation="DLGGEKEKDIAVKLPGVTKNTNSKQSSDSKASFNHPSTFFNNNK
                     RSSNLNYNNSNKKRELMNQEKNKEGNRNKNTMELPKTGEKYNGLPVYVGLFTAIASII
                     GLKKNKF"
     gene            778..1497
                     /locus_tag="ACG930_002571"
     CDS             778..1497
                     /locus_tag="ACG930_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519692.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLISERIIMDTLKELKNQGKTVLIVHHDLSKVKKYFDNIILLNRNVIAHGSVES
                     VFNEENLKKAYGDTIFIGERE"
     gene            1499..2341
                     /locus_tag="ACG930_002572"
     CDS             1499..2341
                     /locus_tag="ACG930_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFQ0519693.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAMGMNVNFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISAAVGASSSLLGLFIGYNFNIAAGSSIVLTAASLFVISFLISPKQKFLRKK
                     ERSL"
     gene            2338..3282
                     /locus_tag="ACG930_002573"
     CDS             2338..3282
                     /locus_tag="ACG930_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFQ0519694.1"
                     /translation="MMRKWKVVVGSLGILIALFILGACSTNSKDKVASNEKLKVVVTN
                     SILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGGN
                     AWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNIE
                     KHLAEKDPDNKKIYKENLDKYIEKLNTLDKEAKSKFASIPNDKKMIVTSEGCFKYFSK
                     AYNVPSAYIWEINTEEEGTPDQIKHLVERLRTTKVPSLFVESSVDDRPMKTVSKDTNI
                     PIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            3300..3531
                     /locus_tag="ACG930_002574"
                     /pseudo
     CDS             3300..3531
                     /locus_tag="ACG930_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
     gene            4409..4678
                     /gene="rpsN"
                     /locus_tag="ACG930_002575"
     CDS             4409..4678
                     /gene="rpsN"
                     /locus_tag="ACG930_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFQ0519695.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAVGDHTDLAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            4693..4872
                     /gene="rpmF"
                     /locus_tag="ACG930_002576"
     CDS             4693..4872
                     /gene="rpmF"
                     /locus_tag="ACG930_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFQ0519696.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            4904..5281
                     /locus_tag="ACG930_002577"
     CDS             4904..5281
                     /locus_tag="ACG930_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519697.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDTQQIQAYLEDR"
     gene            5302..5451
                     /gene="rpmG"
                     /locus_tag="ACG930_002578"
     CDS             5302..5451
                     /gene="rpmG"
                     /locus_tag="ACG930_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFQ0519698.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            5475..6458
                     /locus_tag="ACG930_002579"
     CDS             5475..6458
                     /locus_tag="ACG930_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFQ0519699.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEEQVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKHYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            6488..6610
                     /locus_tag="ACG930_002580"
     CDS             6488..6610
                     /locus_tag="ACG930_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFQ0519700.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            6628..8151
                     /locus_tag="ACG930_002581"
     CDS             6628..8151
                     /locus_tag="ACG930_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFQ0519701.1"
                     /translation="MKKISVGLVGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            8175..8414
                     /locus_tag="ACG930_002582"
     CDS             8175..8414
                     /locus_tag="ACG930_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519702.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSV
                     DTVRRVLKQDRDCCFIKVNTGRSRRLAKRYNSLIN"
BASE COUNT         3172 a         1114 c         1602 g         2616 t
ORIGIN      
        1 gatcttggtg gagaaaaaga gaaagacata gcagtcaaat tacccggagt aacgaaaaat
       61 acaaattcta aacaaagttc ggatagtaaa gctagcttta atcatccttc tacttttttt
      121 aacaacaaca aaagatcatc taatctaaat tataataata gcaataaaaa aagggaacta
      181 atgaatcaag aaaaaaataa agaaggcaat cgaaataaaa atactatgga gttaccgaaa
      241 actggagaaa aatataatgg tcttcctgtg tatgtagggt tattcacggc gattgcaagt
      301 attatagggc tgaaaaaaaa taaattttaa tgtgggaatt attattattt ctctaattct
      361 atttgagcaa tttaaaatat gaaaatcaat aaagagaaag ttttaagttg ttaagtaaat
      421 taaatttcga ttggaagcat agttgaataa gcctaacatg ttacgaaaga taaataacct
      481 acttttcatt tctagaagag aatgtcttga tgcttataaa cagatttagc tccctatcca
      541 cttcaagtct aattcttttg tatgcaaata aagtattttt aggagagtgt tctcattaga
      601 gaacactctt tttttgtttt gaaaactact tactatacgg gtagtttcaa atagttttgt
      661 catcctaatc ttcagcaaca gaaaaaaatc caaattttaa aatttaggct tgactaaaat
      721 atattttctg tataccatat aatcgtgata atcattatca tttagaagga gaaagttatg
      781 ttagaagtga aaaagcttaa tgtttgttat aacgattttt tagcattgaa cgagatttct
      841 ttaaaaatac aagaaggtgc tctaacaggt attattggtc caaatggtgc tggaaaatct
      901 acattactta aagcaatgtt aaatattatc cctcatcagg gagaggtctc cattaataat
      961 gaagatatca ataaaaaact ggtaaagatt gcatatgtag agcaaaaagc tgatattgat
     1021 tttacttttc caataaaagt aaaagaatgt gtatctatgg gaacgtatgc cggaatgaaa
     1081 gtttttcaaa gaattaaaaa tgcagaatgg caaagagttt caaaggcttt ggaaaaggtc
     1141 gatatgggaa aatattctaa tcatcaaata ggagaattat ctggaggaca atttcaacgt
     1201 gtacttttag caagatgtct tgctcaaaat gcggatttca tatttttaga tgaaccattt
     1261 gtagggatag acttaattag tgaacgaata attatggata cgttaaaaga attgaaaaat
     1321 cagggaaaaa cagtgctaat tgtgcatcat gatttaagca aggtaaagaa gtattttgat
     1381 aatattattc ttttgaatcg aaatgtaatt gctcacggaa gtgtagaatc tgtatttaat
     1441 gaagagaatt taaaaaaagc ctatggagat actatattta ttggagagag ggaataacat
     1501 gcttcaaaat tttattaatg gtctgtatga ctttcacttt ttacagaatg ctctaattac
     1561 atctgtagtt atagggattg tttctggaac agtaggttgt tttattattt taagaggaat
     1621 gtctcttatg ggcgatgcta tttctcatgc tgttttgcca ggagtagcaa tttcttatat
     1681 tttaggtatt aattttttta ttggtgctat tgtatttggt ctattagctt ctatcattat
     1741 tacttttata aaaagcaata gtgtaataaa aggagataca gcaattggta ttactttcag
     1801 ttctttttta gcgctaggag ttatccttat aggagttgca aatagctcaa cggatttatt
     1861 tcatatctta tttggaaaca ttttagctgt acaagatatt gataagtgga ttacgattgg
     1921 cgtttctgtt ttagtgttgg ttatagtagt tctatttttt aaagaattat taattacttc
     1981 ttttgatcca ttaatggcaa aagcaatggg gatgaacgtc aatttttatc attatctact
     2041 gatggttcta ttaactttag tagcagtaac agctatgcaa agtgtgggga ctatattaat
     2101 tgttgcaatg ttaatcacgc cagcagctac agcatattta tatgcaaata gcttgaaaac
     2161 tatgatattt atttctgcag cagtcggggc aagctcatca ttgcttggat tgtttattgg
     2221 ttataatttt aacatagccg caggatcaag tattgtttta acagcggcat ccttatttgt
     2281 aattagtttt ctaatctcac caaaacaaaa atttttaaga aagaaggaga gatcgttatg
     2341 atgagaaaat ggaaagtagt agtgggaagt ctggggattt tgattgctct ttttatatta
     2401 ggagcgtgtt caacaaatag taaagataaa gtggcttcga acgaaaaatt aaaagtagta
     2461 gttactaatt cgattttagc agatattact gaaaatatag caaaggataa aattgattta
     2521 cacagtattg tacctattgg gaaagatccc catgaatatg aacctttgcc tgaagatgtt
     2581 caaaaaactt caaaagcaga cttgattttt tataatggtg ttaacttgga aactggagga
     2641 aatgcttggt ttacaaaatt agttaaaaat gcgaacaaag aggaaaacaa agactatttt
     2701 gcagcaagtg atggcataga tgttatttac ttagagggtc agagtgagaa agggaaggaa
     2761 gatcctcatg cttggttaaa tttagaaaac ggtattattt acgctaaaaa cattgaaaaa
     2821 catttagcgg aaaaagatcc tgataataaa aaaatctata aagaaaatct agataagtat
     2881 attgaaaaat tgaatacact agacaaagaa gcaaaatcta aatttgcttc aattccgaat
     2941 gataaaaaaa tgattgttac aagtgaagga tgctttaagt atttctcgaa agcgtataat
     3001 gtgccttctg cttacatttg ggaaatcaac actgaagaag aaggaacgcc agatcaaatt
     3061 aaacacttag ttgaaagact acgcacaaca aaagttcctt ccttatttgt agaaagcagt
     3121 gtggacgata gaccgatgaa aacagtatcg aaagatacca atattcctat ctattcaacg
     3181 atttttactg attcaattgc agagaaagga caagatggtg atagttacta cgcgatgatg
     3241 aaatggaacc tggataaaat tgctgaaggt ctttcaaaat aaattggagg aaaaagagta
     3301 tggtaaaaat taaaccaact actatactga tttatttatt agcaattcag gaattgacga
     3361 aaagaaaaaa agttaaaaaa taaagattta gcaaaaattc taagcattac tccagcatct
     3421 gtaagtgaga tgttggctaa acttagatat gaaggttatt taaacatagg gtgtcaattg
     3481 acaaatagag ggaaagactt tattgacaat tacaaaaaga gctttatata aaagactttt
     3541 tatttagaaa ggataagaaa atgactattg gagtaattat gataggactt atcctaatag
     3601 ctggatataa tttttttaaa tctttcttgg attattttag aaaaggcgaa tgatttagat
     3661 gagtatatta cttcttatag gattactttt ttaatcagct attctgttgc tgctcattag
     3721 tttaggttta agcaatgagt ttaataatag acattaatgt ttaaaaattt atagaattaa
     3781 aaatatcata taaggcgaat tttctcatat agactaggta ctacgtgcca cttactgaaa
     3841 gataatagaa aatgaactaa gttattttca aaaggatgta cttcatcaaa ttaagatagc
     3901 tttgtttgtc tgaacaatct atctaaaaaa gataagttct atcgagatga taggataggc
     3961 ttataattag cctataaatt tttggaatac agctacaatt ctttttcaaa ttagttactt
     4021 aatgtttatt tcttataata taagaattgg tcacaatctt acaaaatcat taataaacga
     4081 gttaaacata aaagattgaa taaaactata gtttctttca taatgccgtt ttaagtagag
     4141 aaaagctact taaaacggta tttatgtttt aatggactaa taaaaatgaa ccattatttt
     4201 ttgcacttaa actacaagtt cttttaatta atctgattat ctctatgtat cgataaaatc
     4261 attttcaaat ggatatctat tcatatgatt tttatttcat gttatttatt gttgacaaga
     4321 gaaatttttg ttggtaaagt gtcaatgtca aaacgtaacg tttacgattt gtgacgtcta
     4381 aatcaaaaca gaaggagtat aaatgtatat ggcaaaaaag tctaaaattg ctaaagcaaa
     4441 gaaacaaatg gcaatgattg aaaaatatgc agacaaacgt caagaattaa aagccgtagg
     4501 agatcacacc gaccttgcta aattgccaag agattcaaat ccaaatcgtc tgaggcttcg
     4561 tgatcagacg gatggccgtc caagagggta tatgcggaag tttggtatgt cccgtattaa
     4621 gtttagagag cttgcccatc aaggtttgat tcctggagta aaaaaagcaa gttggtaaga
     4681 ggaggaaata tcatggcagt accagcaaga aaaacatcta aggcgaagaa acggttaaga
     4741 agaactcatc aaactgtagt aaaaccagaa atttcatttg acgaagcgaa tggtgattat
     4801 agacgtagcc atcatgtatc tttaaaaggg tactataatg gaaagaaagt aattaaagga
     4861 gcttcaaaat agtttaatat ataactttta ggagggaacc aaaatggaaa ttatttaccc
     4921 acctttagtt gaagaaggat taaagtatta tcttgaaacg acccagcaat cgctagataa
     4981 atgcactttt tatcgttcga tggtagagag aggaattatt actgaaacgg gtttaccgac
     5041 ccaacaggca attgaaaatg gattagtcaa agattactat gaggaccaag gcttatcatt
     5101 tgatgatttt ttaagaatct atccaatttt tgaagagtat gacgaggagt tatttcaatg
     5161 tatcgatggt tattgggaga tacctgttga tatgaaagaa aatttagttt cacaattgga
     5221 atctggcgag ttaacttttg aagatacaca acaaattcaa gcatatcttg aagatcgata
     5281 agtattgaag gaggaagatt tatgcgtcaa aatattattt tggaatgtgt cgaaactgga
     5341 gaacgtctgt atctcaccag caaaaataaa cggaataacc ctgaacggtt agaattaaaa
     5401 aagtattcgc caaaattgcg cagacgggca attttcaaag aagtgaaata gctaagtggt
     5461 aaaaaggtga caaaatgggc ataccagtta caatcgtttc tgggttttta ggggctggaa
     5521 aaacaacgct aatcaatcaa gccttgcaag tctcacccta ccccagggaa gaaattatta
     5581 taattgaaaa tgagtttggt gaagttggga ttgatcacaa attattagtt catagcgagg
     5641 aacaggtgtt acaactaaat aatggatgta tgtgttgcag tcttcgcagt gatttattag
     5701 caatattgat ttctttactg gaaacaatag aagaacatca acaaccaatt tcacaaatca
     5761 tcattgaaac tacaggtata gcagatcccc aaccaatcat tcaaacactt ttaacagcgc
     5821 ctcaactaag aggaagagta tatatcgata gtttattgac tgttattgat agtgacagtt
     5881 ttgaacttat tgaaagagaa ccacaagccc ttaagcaact tgtcatggca gatcgcattt
     5941 ttgtgtctag aaaacaaaac ttgaatttat ctgcactaaa aaaattacag agagaaatca
     6001 aaagtattaa ccctttatcc gatattcgaa tgttcacaca tagtgaaacg attcaaaaaa
     6061 aggattttta taatttgaaa aaatttaatc atcccttagt ttttgaaagt gattcatcag
     6121 aaaatcacta taatggcaaa cactatcatc aacaccatca agtacatgag tttaaatcaa
     6181 ttctcttaac ttcagatcaa gacataaaaa aagatttttt actccaatgg attgactggt
     6241 tgattttaac caaccaaggg agcctgtatc gttttaaagg attgattgct ttacaagagc
     6301 aggattttat agttgccatg caaggggtaa acgaacaggt taattttcaa tacaccactc
     6361 gacaaaaaga ccaaaccact attattctaa tcggaaaaat gttggatgaa gaaaggatca
     6421 aacagagttt tgataaatta ctggcggaaa gcaaataatg ataagtattg attgggggta
     6481 atttctaatg gagaaaacgg atatatctag tgcatatcga cgacttaaaa gcccgaatat
     6541 taaaactaga aaaagggcat taaaaattat caaagaacat aaacgaaata aaatgaagaa
     6601 attagcataa ttaaggaagg aaaaagaatg aagaaaatca gtgtaggact tgttgggata
     6661 gcagctctag gattattggg agcttgctcc agcactaatg atgcaaaagt atcgaatgat
     6721 aaagatggaa aattagaaat tgtaacaaca ttctatccaa tgtatgattt caccaaaaac
     6781 atcgtcggcg atgaagcgaa cgtggattta atggttccag cgggatcaga acctcatgac
     6841 tatgagccct cagctaagga tatggcaaaa gctcatgatg ctgatgtttt tgtatatcat
     6901 aacgaaaaca tggaatcatg ggtaccaaaa gctaaagaaa gttggaagaa agctgggcct
     6961 aatgtagtag aaggaacaaa agacatgatt ttattgccag gtagtgaaga agaagatcat
     7021 gatcacggag aagaagatca ccatcatgaa ctagatcctc atacgtgggt ttcacccaaa
     7081 atggcaatta aggaagtttc aaatatcaag gatcagttag ttaaattgta tccgaaaaaa
     7141 gcaaaagtat ttgagacaaa tgctgaaaag tatttgacta aactgaaacg gttggatgct
     7201 gactatacca ctagtcttaa agaagcgaaa caaaaaagtt ttgtgacaca acatgcagcc
     7261 tttggatatt tagctttgga ttatggattg atacaagttc ctattgctgg actaagtcct
     7321 gaagaagagc catcttctgg tcgattagct gaattaaaag agtatgttaa aaaaaataag
     7381 atcaattata tttattttga aaagaatgct aatgataaaa tcgcaaaaac tttggccaat
     7441 gaagctggga taaaattgga agtattgaat cctcttgaaa gtcttacaaa agaacaaatg
     7501 gataatggtg aagattatgt ttcagtaatg gaagacaatc taaaagcgtt agagaaaaca
     7561 actatggttg ctggtgaaga ggtagttcca gaaaaagaag cgaaggatga aaagacagtt
     7621 gctaatgggt actttaaaga tgccgatgtg aaggatcgcg aattgagtga ttatacaggc
     7681 gaatggcaat ctgtttatcc gttgttaaaa gatggaattt tggatgaagt tttcgattac
     7741 aaagcaaaac tcaataaaga catgacagct gccgagtaca aagattatta tactactggc
     7801 tataagacag atattgatac tatcaacatt aaagacaaca ccattgattt tgtagtcaac
     7861 ggtgaacatc atcaatacac atacaaatat gttggataca aaattttgaa ttatgaaaaa
     7921 ggaaaccgtg gtgttcgttt taattttgaa actgatgatg caggtgctgg tcgttttaaa
     7981 tatattcaat ttagtgatca tggaattgca ccaagtaagg cagagcattt ccatattttc
     8041 tttggtggag aaagtcaaga aaaactttat aatgaaatgc ataattggcc tactttctat
     8101 ccagcttcat tatctgagca tgagattgct caagaaatga tggcccatta aaatccaatc
     8161 tttggagaaa atacatggta agaaaagtat tattgtctat ggattccaag aatattgatg
     8221 cttatcggcg ttatcgattt gcaaagcaaa tgagattaaa tgggagtaca ttagctgata
     8281 ttgctgcaac tttacatgtt agtgttgata cagttcgtag agtgttaaaa caagaccggg
     8341 attgttgttt tatcaaggtc aatactggaa gaagtagacg tttagcaaaa cgatataata
     8401 gtttgattaa ttagttgtaa cagtagagca gattaatttt cttttattag gatttgatct
     8461 gctctttatt atgtatagga attaacatat tcgaaaaaat atta
//
LOCUS       DAZKPE010000093         8423 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000093 DAZKPE010000000
VERSION     DAZKPE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.094"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..504)
                     /locus_tag="ACG930_002583"
     CDS             complement(<1..504)
                     /locus_tag="ACG930_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519703.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILIS"
     gene            470..2107
                     /locus_tag="ACG930_002584"
     CDS             470..2107
                     /locus_tag="ACG930_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519704.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2252..2992)
                     /gene="truA"
                     /locus_tag="ACG930_002585"
     CDS             complement(2252..2992)
                     /gene="truA"
                     /locus_tag="ACG930_002585"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFQ0519705.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3183..3818)
                     /locus_tag="ACG930_002586"
     CDS             complement(3183..3818)
                     /locus_tag="ACG930_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFQ0519706.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3965..5185)
                     /gene="sstT"
                     /locus_tag="ACG930_002587"
     CDS             complement(3965..5185)
                     /gene="sstT"
                     /locus_tag="ACG930_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFQ0519707.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            5753..>8423
                     /locus_tag="ACG930_002588"
     CDS             5753..>8423
                     /locus_tag="ACG930_002588"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFQ0519708.1"
                     /translation="MNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFICY
                     LLAVSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLFVHKSYFLVAAF
                     FYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLLLLISNRFW
                     YALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVSPVLLIVGGLIL
                     LLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSPSFLLFNLF
                     KVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYNTKADEINQ
                     TRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLMLSVGYGGG
                     TANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHPFTAALYRR
                     KQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNTETSQFIQL
                     STMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKFIQEIDKID
                     KPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNKEVVAPNNF
                     GAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTEDSQIIQEK
                     NLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2784 a         1547 c         1293 g         2799 t
ORIGIN      
        1 actaatcaga atcgtacaaa tatttaataa ccaaatatat agaacataac ttaatattaa
       61 gttatttgaa attccataaa aaacgactgc aggaattatt gtaagaaaag gataaaaata
      121 gttcagtcca tctccataat tgttaaatgt tgtatagttg attggccctt caaaaataga
      181 agataaccct ttgattcgtg aaagatgaaa agataaatca cctgttgtat aaatttcttg
      241 agcatttctc ataaaattta ctgaatataa agtactaagt aagataagaa ctactaaaag
      301 aaatgctttt ttacttattt tcatagattt gttgttctcc ttttttaatt ctattttcag
      361 tatactagaa ttgtcttttt ttaataagtt ttgcgttaaa tttttcatag cactagtatg
      421 atatactaga aaagaatcaa tttttattac ttttaaatag gagaaaaaaa tgaaaaaaaa
      481 caaaaaccaa ataatagata tcatttttat gttatttcta agttttgctt acgtcatccc
      541 tctattcatg tctatgggaa tctatcatag tgtcaatcag gatacttact ttcatttatc
      601 tcgaatcata ggactagata atgtatggag ttctccagta aacttcaata acttcgatca
      661 tcatggaaca atgatgaata ttttttatcc atggcttact ctttatccag cttttttatt
      721 ttataaaatg atgggaaatc ttgttttaag ttataatatc tactattttt ttatcacttt
      781 tttaacaatg gtcgtttctt atttttctat gaaacaaata aaaaacaatc gttatatttc
      841 gctgttattt tcgattattt atacattttc cgcctatcgt gccattgaca tattccatcg
      901 tgcttcattg ggagaagctg tcgctttaac atttttgcct ttgatactaa tggggtgtta
      961 cgaaatttat attagagatt accaaaaatg gtactggttg tctattggca tgacgctagt
     1021 agtgtatact catttacttt ctgtcgctat ggtttctgta tttattggag gaacgttgtt
     1081 tctttctttt tatttttggg accaaaaaat cgctagactc ttaagtcttt taaaagctac
     1141 cgtcctcacc ttttttttaa gtgcgggatt cttaattcct tttattcaac aatctagagc
     1201 acaagaattg aaagtcccac tgggaaaaga attaagtggt atggctccta gtgatatgct
     1261 gacacacatt ttaaataata actataacaa ctatactatt ggattattct tatttctcgg
     1321 attgattggt gcttttattt ttataaaaaa attaactgct gatgatttat ttattttctt
     1381 tcttggtgta tttgttcttt tttgttcaac caatttattt ccttggcaac tttttaacca
     1441 tacaccagtt aagagtctac aatttgtctg gcggttaaat ggtttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt tagctgtaca cataaacagg ctaaaaagtc
     2161 tttttttata tttctttaat ttgcttcata cattatttaa catcgatatt tatactgtga
     2221 aacatgcgtt tcatccatta tcaaagtatt tttatcgata ataaacttca tccaaaaaca
     2281 gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca aatatttcat
     2341 cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc atgataatcc
     2401 gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt tctccctttc
     2461 gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt ttcaatgcag
     2521 aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc agcttgtcca
     2581 tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa ggaatcacgt
     2641 tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa tggaagcgct
     2701 caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga ttcataaagt
     2761 cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact tgtcctcgcg
     2821 catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca tttgtcatct
     2881 gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca agtctttgcc
     2941 atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc atattttagt
     3001 ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag cacaaaatat
     3061 agctcctttc ttctctaaaa cagaagctat acaagaaaac tgtggaaata tatatttcag
     3121 aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg acggctcaag
     3181 ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt aaagaaaaaa
     3241 ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat agaaggaatt
     3301 cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc aaggtataag
     3361 tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac tggaaacaat
     3421 aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga gacattccac
     3481 gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc tataccatag
     3541 aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac aaatgcagca
     3601 tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca aataagaaac
     3661 gcttttctta caggactgga aacctctcca aatacactga tcacgctctt catttgatct
     3721 aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag cacgcctaat
     3781 aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca ataacaatta
     3841 cctatgcttt taattgttat tataagcgac tttatcttga tttaacagaa acctctattt
     3901 acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac taaatatcta
     3961 acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt tccccacttc
     4021 ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac gaatttaagg
     4081 cagtttccat tgaatcctgg ataacaccga taataaatcc aataccgacg atttgcatcg
     4141 cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac agtgaaccgc
     4201 ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa aggactttca
     4261 aaacaaaagg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc aaggaaatgg
     4321 taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg gaataagact
     4381 cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt gcggcagaac
     4441 ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc aatggatagg
     4501 gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg acaaacagca
     4561 tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagct attccagtcg
     4621 tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca ataatcactt
     4681 gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc gattctgaac
     4741 gtgctcgaaa agctagtccc aacaatacag cccagaataa gacgccaagg taattcgcat
     4801 caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat aaaacacttt
     4861 ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga acagtaaaaa
     4921 ttgaacttac aataactgct acaagtgcag aaagcaatgt tcccactaaa tataagatca
     4981 aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac gccatcgtca
     5041 agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac gttcccaata
     5101 ttgaaataaa tgtccatgtg gggaaaaaga taccaaacaa tattccgact aaaataccaa
     5161 caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga ccaccctttc
     5221 acaattttaa caatcattgt atcattttat gcaaagaaac taaaggtata attttctaaa
     5281 aattctaaca atacaaacaa ccatttcttg ctaattttgt actttttctg tctacacgtt
     5341 gttttttgag atattctaag ttaggatgtt attaatgggc aacttatcag gaaacgtttt
     5401 cttatgtttt tgtccaattt ttttgtgagg tgtttattct tgaaaaaaat aaagaaggag
     5461 agttatggct tcctgacaat ctttgtcgct tgtataatga tggttttaca gcgtatattg
     5521 atttcagcag tcactattcc tacatatgca acaaaccctg gtcgattcta catctataca
     5581 tttttacaaa cttccgttgt tattggtgca aatttgatcc cactttacat gggttaccaa
     5641 tatcaaaaaa tcgcccgttt aaaagtttta cattatttaa gtcgttttgc ctttatattc
     5701 ctaatagcca cactagtttg caatatcttt tttttacgta caagctggca gcttgaatat
     5761 tcgtgattat tggcttatcc taacacctat cagtcagaat tactttactt atgctgtttc
     5821 ttgtactttg cttttttgta gtattcctta tacagttgga tttttaaata aattatcgaa
     5881 aacaacaatt aaatatctac tattattttt aacaattgga ttagttggct gctctactct
     5941 atttaataaa gacccgtttg cattacagaa tggacagagt attttatgga ttttttattt
     6001 atttttaatg ggttatggtt tgaaagaatg gaactggaaa gaaaaggtcc gctataagct
     6061 tcctcaagta tttatcagct tgattgtttt attcggtttg attattttga tgacacaaat
     6121 ttcactcatc atcagaggaa atacagatac agcgctgagg ttttctaaac catattctct
     6181 cttcgcaatg tattatactt tctcttcgtt tttattttta gaaatgctat ctgataaatt
     6241 aggtataaaa ggaagaggaa attttcttgc tgtatttttg attgtcactc aagttatatg
     6301 taatttccct ttagtttctt atcgcgtatc tacatttatg aaacgtgaat ttccaaactc
     6361 agggaaggca tggctgataa atatcgggca gttttttatt tgctatttat tagcagtgtc
     6421 cctcctagtt atctttttat tttatataca aaaaatccgt ttcattcatc gtttcatcga
     6481 atacttcgct tttgattcga ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg
     6541 gctttttgtt cataaaagtt attttttagt tgcagcattt ttttactgct ttaccttcgt
     6601 gcagattttc gttttagaac caaaagaagg ttggaaagaa actatccagg ttgccttaaa
     6661 aatatttact cagcgacaag cacccatgat cctgacaatc atcattatta tgggattttt
     6721 cttcttacta ttgttgattt ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat
     6781 taacttactg ctcactattt cgacagtaat caaaatggaa atgcgggaag agcctgtctt
     6841 tccttcagat ttaaaaatac tgaccggatt gtcagaacta ttatcgatgg ttagcccagt
     6901 cttattaatc gtgggcggat tgatccttct cctattattg attactagta ttattgtaca
     6961 acgtagacta caaaaacagt attccttgaa gattcattgg aaacgtcgat ttatcagtat
     7021 cgctgtatta ttaggatgtt tttcgggtgt ctttttcatt aatcacaaaa attcgccttc
     7081 tttcttgctg tttaatttat ttaaagtaaa caagactttc tttaaccagc aaggcgccgt
     7141 aaaagataac ggaccagtca ttcaattcct aaacaatatc gacattaaaa tcatggaaga
     7201 acctgctggc tattcgaaag aaaaaattaa tggaataatg aaaaagtaca acacaaaggc
     7261 agatgaaatc aaccaaacaa gaagtgactg gttaaacaat cagacgatcg ttctcaattt
     7321 aagtgaaagc ttcagtgatc ctgcacgtgt ccctaatctg acagtaccta cagaccctat
     7381 tccttacatc aaaagcatta taacagaagg aacaggagga ttgatgttat ccgtcggtta
     7441 tggtggcgga acagctaaca tggaatggga aggactgaca ggcttgagta tcagtaacct
     7501 gtctgcttcg ttagttacac cttataccca gctagtggag cgtcagaaaa taagtccaaa
     7561 tattaccgat ctattcgatg aaaaaatagc catccatcct tttacagctg ctctttatcg
     7621 cagaaaacaa gtgtttgata aatttggttt tgacaggttc tattatttag acagtccgga
     7681 taaattaact tatacggata aaatagaaca aagcccacgc atatcggatg attcagcata
     7741 caaagaaacc ttgaaagctt tacaaagcaa tacagaaacg tcacaattca tccaattatc
     7801 cactatgcaa aaccatatgc cttatgatga ttactatagt gaattgaact acactgctga
     7861 aggaactgct gtcattccta atagaagaaa agaattacaa acttatatgc aaggccttca
     7921 ctataccgat acagcagtaa aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat
     7981 tacctttgtt ttttatggtg accatttacc cgcaatctat agtgggaatg attcgaaaaa
     8041 atatggatta gaacagcacc agacagatta tttcatttat aacaacaagt atagtcgtga
     8101 acaagcagct acgttaaata aagaagttgt tgctcctaat aactttggtg ctatggctct
     8161 tgagcatgcg aatatcaaag taactcctta ctatgcgttg ttgacagaag tatctaatca
     8221 tctacctgca ttaacaattg atcctacaga aagcttgtct aatcgtttta atggaaaaca
     8281 ggtctttgtt acagaggata gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa
     8341 agaaattcta gaagattatc gtctgataca atatgatctt gttgcaggta accagtacag
     8401 tgcaacatgg gcgacacaaa aaa
//
LOCUS       DAZKPE010000094         8095 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000094 DAZKPE010000000
VERSION     DAZKPE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.095"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            283..1803
                     /locus_tag="ACG930_002589"
                     /pseudo
     CDS             283..1803
                     /locus_tag="ACG930_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(1990..2562)
                     /gene="hxlB"
                     /locus_tag="ACG930_002590"
     CDS             complement(1990..2562)
                     /gene="hxlB"
                     /locus_tag="ACG930_002590"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFQ0519709.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(2569..3231)
                     /gene="rpe"
                     /locus_tag="ACG930_002591"
     CDS             complement(2569..3231)
                     /gene="rpe"
                     /locus_tag="ACG930_002591"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFQ0519710.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(3247..3762)
                     /locus_tag="ACG930_002592"
     CDS             complement(3247..3762)
                     /locus_tag="ACG930_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HFQ0519711.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(3764..4048)
                     /locus_tag="ACG930_002593"
     CDS             complement(3764..4048)
                     /locus_tag="ACG930_002593"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFQ0519712.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(4082..5410)
                     /locus_tag="ACG930_002594"
     CDS             complement(4082..5410)
                     /locus_tag="ACG930_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFQ0519713.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGILGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(5424..5879)
                     /locus_tag="ACG930_002595"
     CDS             complement(5424..5879)
                     /locus_tag="ACG930_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519714.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(5882..7828)
                     /locus_tag="ACG930_002596"
     CDS             complement(5882..7828)
                     /locus_tag="ACG930_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519715.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVFR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2680 a         1531 c         1269 g         2615 t
ORIGIN      
        1 ttgcggtacg aagaaagatc gcttcaaggc tctttactag gatcaaaatg gatttgtatt
       61 aatgtacaaa agatttgaaa gtgggtacct tcaatggccg cgttccagaa aagaagtctt
      121 actgactggc ctttcaatcg aagaaaaatg tacgctaaaa gaaacgaaaa aaggtgcgat
      181 atattagacg aaaaccttgt taaatcaagg attttgtctg tttttcgttg tcataaaatg
      241 gtataataga tgtaagaaaa tcgctagaat ggtggtgtaa aaatgacaaa attggaatct
      301 gaacttcttg tacaaatcaa gcaattaaca cagttgcttg aaatccagca acaggaaaat
      361 actcttctta gagaacaaat tgctgaaatg aatcgacgct tgtttggacg aaaaaaagaa
      421 acaccacccg tagatgggca aatcgattta ttagacgact caacttttaa tgaaccagag
      481 cacactggac aagaaagcca ggaacccatt acggtatctt cttttaaacg cagaaaacgc
      541 aagggactca aagcactttc attagaaggt ctgcctgaag ttcctattca ttatgaatta
      601 aaaggtgccg attgtttgtg tgaagactgt ggtcatactt tacatgatat cggtgcgaca
      661 aggcttagag aagagccatt gtatgttcct gcccatatag aaaaacaagt catctaccaa
      721 catgcctatc attgcagaga atgtgaagca ttaggagaaa caaaaatcaa aaaagcgcct
      781 gttcctaaac cgttgatcaa taatagtcta ggttcctctt caattgtgac acagagtatt
      841 tgggaaaaat ttgttaaaaa ggtgccggca tatcgacaag aaaaagaata gcatgcactt
      901 ggtttccctc ttgatcgtaa aaaaatcact aattggcata tcaaggtaag tgaaatggtt
      961 ttagagccaa tctacaattg ccttcatcaa gaattaagca atcaggaggt cttacacgcg
     1021 gatgagacaa gctatcgggt attgaatact cataaagaaa agacctttta ctggttatat
     1081 gcttcaggta aaagcgaaga aaaacaagtt gtgctctacg agcacgcaaa ttcgcgttcc
     1141 gttgatgagc ccaaaagttt tttagaatca tttagcggtt tcttgcatac tgatggttac
     1201 gcggcctatg gaaagctgcc ggtaaacaat gtttattgtt gggcgcatgt tcgcagaaag
     1261 ttttttgaag cattgggtaa acaaccgtcc ccaaaaagtc atgccaaaat aggattagac
     1321 ttctgtgaca agatgtttcg aatcgaacgg acctttaata agcttagcgc agaagaaagg
     1381 tttgtagcga ggaaggaaac gttgcagcct gtgatgactg aattttttca ttggtgtgag
     1441 agttttgctt atttgccaaa atcgcagctt ggaaaggcgg ttcaatacgc agtcaatcat
     1501 aaagacggac ttcagattgt gttgcttgat ggacgcttgg aactttcaaa taaccgagca
     1561 gagcgtgcca tcaaagagtt agtgatcggt cgaaaaaact ggctattttc taaaagctta
     1621 aaaggcgcta gatcaaatgg aattatattg agtattatcc agacagctgt tgcgaatggg
     1681 ttaaacatcc gcaaatattt aaatcatctt tttacagaga ttcccaatct gtcttcgatg
     1741 acacctgaag cgctacgcgc ttatttgcca tggaatcagc agatacaaga aatctgtaaa
     1801 taatataagc cacaaataac ctgatttgag tgtatcaaat cgggctattt gtgtttaggt
     1861 accattctat gacacgctta cgctcaaaac tactgaatta ttaagttatg tctaatcaaa
     1921 taaaaaaacc attctcatat ttgctgaata attagcattt agagaatggt tttttatctt
     1981 taaaatctac tactcaaaat ctgcatgtcg agcaaacatc gtttctgagc tttcacctgt
     2041 tttatccatt aaagataaca ctaaactatc aaaggtgaga aatgctaatt gttcaaaact
     2101 tgaacccata ggttgtgaaa aagtatcttc ttctcgttga ttttcatctt tggtaatacc
     2161 tggtaataca agaacagaat ctgctaattg accaatcgac gagtcttttt tcatggtaac
     2221 taaagcaatg cttacaccac tttgatttgc tttggccgct aaatttttta aactacctgt
     2281 ttcacctgag ccagaacaga taattaataa atctccaggt tgcgaatgtg gtgaactaat
     2341 ttcaccgaca aggctgactg aaaaacctaa atgcattaag cgattcgtaa atgcttgcat
     2401 ggcaattcca gagcgtcctg caccagctag aaagatgtgt ttagcttgaa caattttctc
     2461 actaaattgt tctaactcta cagaattaat acgttttgag ttattttgta attctaagat
     2521 aatcgcttct aaatagtttt tattttggtc tttattggtc atgatctttt acttcacttc
     2581 ctctaatgat tgatttagtt tatcaatttg ttcttgcggg gtatttttcc cattgaagat
     2641 gaaaccgcct gatacaaaaa tatccgcccc tgctttagaa caaactttaa tcgtttgatt
     2701 atcaatcttg ccatctactt caatatcata cgtataatca ttttgtttgc gtattacatc
     2761 taactgttcg attttaacta ctgtctcttg aataaaatgc ttattctctg ttcctggatt
     2821 aattgtcatt actaatactt gatcgactaa agataatact ggttcaataa aactgactgg
     2881 tgttgcagga ttaaaagtaa tccctacttt tgctcctgct tccttgacta actgaatgac
     2941 cttcattgcg tgtttggtag cttcaatgtg gaaggtaaca atatctgctc ctgcttctac
     3001 aaatcttgtg acaatttttt ctggtgtatc aatcatcaaa tgaacatcaa acacaacgtc
     3061 tgttagtgga cgaatatctt taataacact tggtccaaaa gccatatctg gtacaaaaca
     3121 gccatccatt acatcaatat gcaaataatc aacattcttt tcttttaaga tttcaaataa
     3181 ctctttaact tctgcgatag gtgcatttaa caatgatgga gcaattgtca ttctctattc
     3241 ccccgtttat tctcccataa tcatgagatt gattgttcta gttcgctctc ttagttgatc
     3301 ccaatcgaca aaatagacac ggcccatttc tcctaataaa agtttacctt cttgaacaat
     3361 taaagtcatt gagttggttc cataaataga tgaacgtaaa tgtgcatcgg tatttagcat
     3421 gacccatttt tctgcagggt aattgggatc agataatctt gttccaaaat caatgtgttt
     3481 tggccccgga ctgttgtatt gattttcact cgtcattttt ggaataatcg tttccattac
     3541 attgttgatg tctacatgta aataatcatc accaaaaaag tttgtgtcat gcatcgtttc
     3601 ttcaaaaaag agtgagcaag ttgtatgcgg gctcgaaatt actaacattc cattctcaat
     3661 acctgctgta tcaactgtat ctaaaagttc ttttcgaata tcatgatacg aaggacgccc
     3721 tgaaactgtt tcaatagtca aagtgtcatg atgaaaacgc atattaaaca cctaatcttt
     3781 cttttacatc tgcataaatg gcatctgtac caatacctgt taataagccc aagccattcg
     3841 ttactttagc tttaattaca tcagggacaa ttgttgtact tactacagca tcatattcat
     3901 caattttatt tagctcatca gcaattttag attgataaat tttcacttga tctgttaatc
     3961 cttcttcttc caaccatttt gataattttg ctactgcaat tgtagaagta gcatgacctg
     4021 ctccacaaat aactaataat tttttcatat tgatctcttc tttcgtattt taattttatg
     4081 attaagcttt cttcactttg ttcatgtaga tagaagcacc tactaaaaca actcctaatc
     4141 cacctattcc aattacacca aagtaagatg ctaataaaac aaacaaccct actggccata
     4201 atccacataa caacatagtt actaatcctg ctgtccccac atcgaaactt gctaatgtaa
     4261 acacatcagt gataattggt gccaaccatg ttgccatata taatgttgta acaacataca
     4321 acgaacatcc tactaatgat ctcacaatat ttcctttaaa ataaggaatc attaaacaga
     4381 tggcgaaagc aaagaatgct aaatctccaa aaggtaatac tttattacct ggaagaatta
     4441 gtgctagcaa taatgagatt ggtacaagca atagagaagt tgacataata gttggatgac
     4501 ccacagttaa cgctgcatcc attccaatgt ttacttggcg accatttaac tttttattcg
     4561 taaattcttt cgccgcttct gcaattggca ttaaaccttc cataaacatt gctaccattt
     4621 taggcataat cttcatcact gccgcagtca taattcctaa gtttccaatt cctgctacgt
     4681 catagcctgc cataataccc actacaatac cgataattag gccaataaca actgtgtcac
     4741 ctaaaatacc gaaacgtttt gttaatgttt ctgcatctgc atctatttta ttaaatccag
     4801 gaatacgatc aaaaacccaa tttactggtt tggcaaatag tactcctgat aatcccatca
     4861 tatgtgtgat agagattcct ggatagccga aaaattcgct aacagttttt tgtgtacgat
     4921 ctgctaagaa ccattgtaaa attactgcga caatcgcgcc aattaagcca aaccaaaagt
     4981 ttcccgtaac agattgagta atcataccta ggaaaattgc gaaccaaaag ttccaaatat
     5041 caacatttaa tgtttttgtc caacccaaaa ccacaaatat gaagttaaga attaatgaaa
     5101 ttggaatcat taaaattccc aatgatgtag agtaagccaa aggtccacca acacctacgc
     5161 caatatctag gatattcagg ccaccaccgt attgttcccc catttgttga attgctgttc
     5221 ctaaaccatc tgataataaa cttaaaacta atcctaaacc aatagaaccg ataccaacag
     5281 taacgccgga aacaaatgct ttaccaggtt ttaatccaaa taatatcccg attacaaaaa
     5341 taatcagtgg taaaaagacg tttgacccta atccaataaa ccattcaaag gcatttaaca
     5401 caatatccat ctctctattc ctcctaataa actcctgcag aatgtactaa ctcaataaat
     5461 gcttctttcg tggtacatgc aagtaattca tttacttttt cttcattttg aaataggcta
     5521 actaagtttt gtagtgtatc aatttgttca tgaggttgtg acattgccaa cataaagact
     5581 aaacgtacag gtatttcatg agatttatct gtcatatctg aaaataccag tggttccttt
     5641 aatgaggcaa aacagatttg agagctattt acatgtgcgg aatctgtatg tgggatagca
     5701 aacccaattt gatttacttc taatccagtt ggaaattctt gttcacggtt ggtgatacct
     5761 tctaagaaac tatctttcac gcaaccagcg ttttttaatt gttcagacat tacttgaaac
     5821 aattcttttt gatctttcac ttctaattga aataaacata attctttatc tagatacatt
     5881 tttattctcc tttttgttga aaaattctta gtaatttttc gctatcatga acttgtaaca
     5941 agcgatcgac catttctttt tgcccaataa attggtaaag ttcttcatat actcctctaa
     6001 tctcagatac atcttcttca gctaaactaa ccataatgac taatttgact tttcgatcgc
     6061 cccaattaat cgcatttttt aatgctacaa taaaaatgtt ggattcaatg accattgatg
     6121 gattcgcatg cggtaaagca acaccacttt ctaaattagt attccccatt ttctctctag
     6181 agaagataga agcacgaaac tcttcagtaa ctaatgaatt ggcttctagt tcggaaatca
     6241 tcaaatccaa acattcttct ttgctttcca cctgtactcc tgtttttact aaagatgatt
     6301 gaacaaattt agatatggtg ggaactttaa ccgctttagg aatcagttca ttttgaataa
     6361 atcgcgaagg ttcttctatt aaatatttag tataagcttc cataatattc atataatctg
     6421 ttttacttac caatggagat acccttacta agggtatacc acctgcatca aaggaaagag
     6481 aggaaataat caaatcaact tccccaattt cagctaaatg aaacttatct aaagttgata
     6541 tttctacatt atcttttgct ggtaaaaacc gtcgaacttt attgtaaatt aattgcgcag
     6601 aagaaatacc gtattggcaa ataatgataa tattatttgc tttggactga tcttcaatag
     6661 caatctgaaa atgaatcaaa attaaggaaa cttcatcgtc cgttaaagtc acatcaaatt
     6721 cttcttcaag gatggacatg gcgtaccata ctatgctaaa gagttctgaa tattgagatt
     6781 tgatattttc taataacgga ttttgaattt taataccttt ttttaaacga aagaccattg
     6841 ctggcacatg atacaataag gattgatata atcgatcatt ttgagtcaaa tcaatttttt
     6901 caatctcact cattctttca atcaatttat gaacgctcat agcgtactct tcattgctgg
     6961 tttttaaatt atttgtcaca cgatgtgcaa atagttgacg acatagatat tctttatctg
     7021 cgtcataaaa tggaagattc aattttgcct tcaattcttc aattaaacca tttgccacaa
     7081 tgtacgtttc catatagcga atgctattga agaggaattc ttcttcaaca gttaaatgat
     7141 gacctttcag taaacggtta cattggataa ctaaagtaga aatcaatgac cgaacatagt
     7201 aatcagaaac cttttcagtc agttcactgt aatcattgaa tagcaaatca tgaatgacac
     7261 taataacttt tgaatcaaac aacatattta aaacttgaaa aaatgttttt gattccatgt
     7321 cattcgcata atagaataca agttgcttga ttgctcgttg aattgcttgt tcattaccag
     7381 taaaactaat tccttctgca gatgactgca acttaacttc tccactgcca ataattttat
     7441 tgataattct caggtcattg tataacgatg ttttactaac cataaaactt tgagacaaat
     7501 gagttaaaga aacaggctta tcaccaaaca aaacttcttt aatgatctcg acacgtcttt
     7561 tttctggaga ataaatatct ttttcaagat aattttctac cgatgaaatc aaatgttcaa
     7621 cgtttttcct atcacctatg agtttgatac ccaaagaagg taatcgctca attgttactt
     7681 ggtaattaac tacataatct tccaacaatt caatatcttg ataaatggtc ttggtcgaca
     7741 ctgccaattt atcactaaaa aaagaagcgg gtttaaagtc ttcttgtcga cttaataatt
     7801 ttaataaatt tacatgtctt tcaatcaaac ttgttcacct cttaacgcta gcatttgtta
     7861 cctcttttca ttatttattc tagcactgga acccccttcc ctcaattaca tctatgtcaa
     7921 taatacttgt ggaagtttgt tgtaaaggaa atccaaataa tcttaaaaaa tgagaaacaa
     7981 aaaaggagaa atccttaaaa gagctaagat attccaatag aaaatactcc ttattatgga
     8041 agtaatatga aatattacaa ttgaaaaata aaaacaatat aatggcgtca ctaaa
//
LOCUS       DAZKPE010000095         7992 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000095 DAZKPE010000000
VERSION     DAZKPE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.096"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..75)
                     /locus_tag="ACG930_002597"
     CDS             complement(<1..75)
                     /locus_tag="ACG930_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase"
                     /protein_id="HFQ0519716.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRV"
     gene            74..922
                     /locus_tag="ACG930_002598"
     CDS             74..922
                     /locus_tag="ACG930_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0519717.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1568..1774
                     /locus_tag="ACG930_002599"
     CDS             1568..1774
                     /locus_tag="ACG930_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFQ0519718.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(1976..2977)
                     /locus_tag="ACG930_002600"
     CDS             complement(1976..2977)
                     /locus_tag="ACG930_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFQ0519719.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(2982..4895)
                     /locus_tag="ACG930_002601"
     CDS             complement(2982..4895)
                     /locus_tag="ACG930_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0519720.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(5063..5569)
                     /locus_tag="ACG930_002602"
     CDS             complement(5063..5569)
                     /locus_tag="ACG930_002602"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFQ0519721.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            5729..6169
                     /locus_tag="ACG930_002603"
     CDS             5729..6169
                     /locus_tag="ACG930_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFQ0519722.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(6195..7310)
                     /locus_tag="ACG930_002604"
     CDS             complement(6195..7310)
                     /locus_tag="ACG930_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519723.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(7355..7711)
                     /locus_tag="ACG930_002605"
     CDS             complement(7355..7711)
                     /locus_tag="ACG930_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519724.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
BASE COUNT         2339 a         1538 c         1220 g         2895 t
ORIGIN      
        1 tactctcctt gtatctttaa cattaatgag aacggaaaaa atgataatct tattatgaaa
       61 atgaggaatt ctcatgagcg tctccataag actacaaatc aaaacaatgt acaacgactt
      121 cagcccaaaa gaacaggcta tcgccgatta tattttagaa aatccaagca aagtaagtca
      181 tagtcctatt agcaatttag caagtgaact gggcattgct gactctactt tttttcaatt
      241 tacaaaaaaa cttggttata atggatttaa agattttaaa atggccatgt tgatccaaga
      301 aaatgatcta tctgctattt ctatccacga aaatattcag aaaacagata ctgagctcac
      361 tatggcgcaa aaggtgttcg agtctagtat ttcaacttta aatgacacaa aaaagttgtt
      421 acaacaaaag gatctaaaaa aagcggctac tattatcaat gaatctaaac gtgtctattt
      481 tttcggtgtt ggcggttcag agattgtagc aactgacgct tatcataaat ttttgcgttc
      541 ccctatcgca acttctcaca gcacggatta ccatattcaa ttgatggaag cttctttatt
      601 gacggaaaaa gactgtgctg ttttgatttc tcacacaggg caatcaaaag aaacaatcca
      661 tattgctgaa accgtaagaa aaactggagc aaaaacaatc gttattacta gccaagctaa
      721 ttcttccctt gctaaacttg gcgatgtcgt ttttatttct atttctgaag aaacagaatt
      781 ccgatctgaa gctttagctt cccgtatttc tcaactaagc attttggact ctctatatgt
      841 gattttgatg ttttacaacg aaaaagaatc acgtcgttct atcgctaaag ttcgacatac
      901 tatttctgaa atcaaagaat agcaccataa cagaaaaagc gaaaaatcca taaaacaaaa
      961 aaagccacta ccaaatattt ggtagtggct tttttggttc tgcaagggtg gtacagaaca
     1021 tcaatagtcg gtgggttaga acgtatgtca tcgcatcttt ggagaaggtt gtattggtat
     1081 tattcgagtt acttgttaga tgcgataaca aagttagtat acagtagtaa aaaatttatc
     1141 ttttcttttt tttattattt ttgtttctta ttttctaaaa aattaaaaaa aattttggtg
     1201 aattaagtat ttccttgata acactggctt ttggcctcat tttaggttat catttgtaat
     1261 tttatttcac agttgatatg attgttatgt aaaataaaaa agtttaggat acatcgaatt
     1321 tttggggaaa ttcttttggg ggtatcctaa atcttttcta ttatattccc atattttcta
     1381 ttattggtct agacgtatga tggtaaactt tgtacctatc tgattgctga atcattaatt
     1441 gcttatcatt agccatcttt gtttcaagtt cgctagatga tcattttatt cacatcctaa
     1501 caaacttgtc acatttatag attcttaatc tatttatcat acaattataa aaaaggaggt
     1561 gctgcttatg aaagctatcc atatttcttt gctttttttc gctagtgcat tgattttatt
     1621 tgctattcat ctttgttccc agccttatat caataacaac ggaatattag tggaaccagc
     1681 attcttttgc ttaccactcg gctttttgtc ccttcttgcc tccgcaggct tcggatttgt
     1741 tgcttttttt aaacgatcaa aacaacaaat ctgacttata aaatttacgt aaaagagatc
     1801 gtgacaataa tcgtgtgata ttcccaaatt tcgaataaaa ggtgcccctt gccatctcta
     1861 actcctcagt cacaagttac aatattcata aaccatgaaa agcttgttta ttgaaattgc
     1921 tccttgtgac ttggagctaa gtgacagatt acaacctctt ttgcatcata agactttact
     1981 ccttgaaaaa cattactaac ttttgatatg tttcttgcgc ttgtttattg ctgaaatcaa
     2041 actgatattc atggttcaaa acagcatttt tctccgcata atctactttt gtgactttca
     2101 cccccgcttt ctcaaataca gaagttactt cttccatttg tttcgtaaac gtatttgtat
     2161 ttccatccgt taagaatgtg ttttgcgtcc aacgatccgc atgtctgacc aaggctaaac
     2221 ttttgacctt ctctgattgt tcaaagtcct tattatcaaa gtaagcccat ccacattttt
     2281 cataaagaaa gctagagatt ttatcactta cttgagtaag tgcagaagga tccaacagac
     2341 cagacaaaga aataaacttc gtaatctgct tgttctccaa agtcggatca agatgatcag
     2401 cttttttaat ttcttcattt tgaagtgcta acaaatattc tccactaatt tgtgcacctg
     2461 ccgaatttcc accaatcgaa atattcgacc aatctgcttg atcttttatc tcttttttag
     2521 ctgcttgaat ggcttcgttc aattggataa ctggtgtagg atgttttgct tccggtgatc
     2581 gttcataatc tatatttacg atgatttgct gcgtgtctga acatagatat tccaaataat
     2641 cacgacaatc atttttatcc cctcctacat atgcgcctcc atgcatccag aaaagaatcg
     2701 gtaatttttt cttttccact ttcggtgtgt agatatccat attattattt ttgtactttg
     2761 aaggatagga tatttctttt tttatatcga tttgttcgat tttttgctgg aaatcatctg
     2821 gtcgggcata tacttgttct ttttcacttg tgtcaaattg ttttctaaca agcaagctaa
     2881 tcggctttgg tgtgatttga ttaatcaaaa atacagtgac taaaataact acgatgataa
     2941 ctggtactgc aatcactatt cgcttgaacc atttcattca tttaccctct ctttcttcgc
     3001 caaatccatg tgataatcgt gctaacagat aaaaatccac ctgaataaat gagaagcgaa
     3061 tgtttctttt ctccagtttt cggcaacatt cttttttttg catctgtctt tttttgtact
     3121 ttcactgtca tctgaatcgg ttgcgtatca tcacttgatt gatcctctcg aggttcattc
     3181 tttcccttat tgtctgcatt ctctgtcgga tcttgctttt ttggtggagc tactgggatt
     3241 tttttgtaat agaaaataat agttggtatc gtctcattaa aaatcccttc agtcggtcct
     3301 tcaacatttg ctaattcgta tccttcgaat gtcttttgct ctgtcatata attttctcca
     3361 taagctccgt aaagctggat ttcgtcctgg tctttgagta gacttttatt gttttcatcc
     3421 acatacttta cgtttatctg atcatggaac actactttca aaaagtccgt tacatgtttc
     3481 gtgtaggcag catggtcaac ttcctgtgcc tttccatgcc ctgctccttc tactaataaa
     3541 agatctttat accctcctga taactcatat aatttttgcg cgttagacac aggtactaca
     3601 tcatctgctg ttccatggat aatcaattta ggcaatgaat ctgacattcc aatcgtaggt
     3661 agagcagctt ttgtatccaa atgcatctcc tgatcaaaat agtattgttt caaaaggccc
     3721 ataaataaat cttcatgctc ttgatcccca atgatgtcta actgattttt tatggcatcc
     3781 ggtagtgcgg gggctactgt ctggctgtac gtaaaacgta gttgttcatc aattgatgca
     3841 aatccgcaat tttcaataat tcctttgaca ttgacaggaa tatctttcgc taatacagac
     3901 atcatcgtag ctgctcccat cgaaccacca taaagtaaaa tcttttgaga tggccgctct
     3961 cgaacttctt gatttatcca gtaaaggacg tcatctgact catattgtcc ataggtcaca
     4021 taatcgcctc cgctattacc agtcgctctg gaatcaacaa ataataaatt atacccggcc
     4081 ttataaaaat cattgtattc ttctgtaacg atcccgttat tccaattccc tcgaaatccg
     4141 ccatggatca tgactgtttt atctgaacct tgatcgacat aatatgcata tacatccatc
     4201 attttgccat cttgtttgtt tagtacagtt tgatgaagtt gttttgtatt tggatagaag
     4261 cctgtgtttt ctgtaggcgt tgtcccatca tctgtacctc caagcatcga catcaacaca
     4321 ctgttttttg caaaagcgat atcgtacaat agataagtag caatcagatg tttgataatc
     4381 tctttatcta caccataatc attaacagca agctcagtga ctaataactc tattaatttt
     4441 gacttgatgt cttctgttgg tccattaagt atttctgtca tctgtttacc gaagtaattc
     4501 aaatattctt taccattgaa attttcacct ttaccgatat catcattttc tgtcccattc
     4561 tctttgtcac ttactttagc agaagaggat tcgtcgtttg acatttttgt agctgttgct
     4621 tcttctgttt gttggttatc tgtggtagcg gtcgtttctt gatctgtgct agtaacagat
     4681 gtctcaaccg ttgtttcagt atttgtttct gtttgtgaag tactcgattt cgtttcattt
     4741 ccagcatcag tagtttctgt ggtttctacc tcccgagatt ccgattcgga agaaatgctc
     4801 tctccatata ctgtccattg cgggacgctt gtacttacag caaataagat gaccaacgct
     4861 ccctttaata cttgttttgt tctcaagcta ttcactcctt tttatgtttc taggagaatt
     4921 atatgtaaac gcaaacattt tttatacaaa aaataaatgg tttatcccat aaaaatagaa
     4981 caggattatt ttctcatttt acgtaataaa gcagaatgga taaaccagta tccattctgc
     5041 tttttttaaa cgaagaaaca acttattgct ccaaaaatgt cagaaatcgt ttatcccaaa
     5101 ttttctcgta aaaagcgatt gtttcctttg ctttcataaa aggattatca taagttgtcg
     5161 ttgctcctct acacatcata agctggtatc ctaatccatg agcaaacttc acagtcgtat
     5221 ctatacaata ctctgcttgt gccccacata attcgatcga atgacagtcc aattcagtta
     5281 ataaaacact caaattagtc ttataaaatg aattcgcatg ggtttttctc acaaaataac
     5341 tgtgctcagg aatagataat tccgacaata gctcccatgg ttttgtttgt ggcactaatt
     5401 gagcatcttc gtgttgaacg aaaataactg gtttcccaat cgtttcgtat gttttgattc
     5461 ttttattcac taatgctgtc actgtttcta attcgtgtat cggcgaagaa tcaaaacata
     5521 cccctttttg taaatcgatc actactattg cgtcggctgt gtttgacata cttgtgcctt
     5581 ctttcttttt tcttgattta atagtatttc ttatctagct agttccatta tacgtgacaa
     5641 cattttctta ttttacacct ctaaatggca cttttcgact atttcttcat gttattattt
     5701 cataaatact tagctattgg aggaatgtat gatgattaaa ttgtatacag gttctgggtg
     5761 ctcgtcttca agacgcgcaa aacgttggct tatcgtccat gatataccgt ttatcgaaca
     5821 gaacttaatt cgtcaaccac taaccaaaaa tgaatttatc cacttactaa aattgacaaa
     5881 caacggcgtg accgaaatgc tctctactca ttctattagt tataaaaatc ttgttcacag
     5941 aatagatgaa ctcagtttga gtgaactata tattgagatt cgtacatccc cttctttatt
     6001 gaaaaaaccg attatctacg accaatctgc aaaacttttg actggattta gcgaagataa
     6061 aatcaggatg ttcctttcta aaactaaaag aaagcaagag ctcaacgaac tcttgctttc
     6121 tggtcatctt gtcgatttta aagaaaataa tctttttgca atgtcttaat tttggcataa
     6181 acaatctgct tttcttaatt aacgaaatcc aatttttcca atatggatct atttttctca
     6241 ttcctgattt ttatgatttc agctttcaga cgcgcccaat cattttttgt aggttgtcca
     6301 ttccagtaaa atatctgtgt attcgtttga tcatatgcct ttttgtcgat aggataatcg
     6361 ctaatgacaa tatcaggtaa ctgatcagcg gatgcactat attttattgg gcgttcagtc
     6421 atagataata tccttttctt tgcccataat tcctgtgttt taccatactt tgattgaata
     6481 tagaatatga caggttgttc gtgttttata aaaatatccc tgactaacat acagtattga
     6541 aaaatcaacc gtctgttctt ttcataataa gtattaagct ctggaattct gcgagctacc
     6601 ccactaaaaa actgttgcat gattggatac atcactggaa atatatgctg aaaatctctg
     6661 tcttctgctg attttccaaa agcatccacc ttcttttttg tcccaaaaac ccttgaatac
     6721 aaatggatca ttgccaaatt gacatataga taattttttt ctgaagttgt aaaacaaatc
     6781 ttgaagtttt tttcaaaatt ttctacaata gacgattcaa tccagcccca actttcttgt
     6841 actttatctg gagtatccaa caaatcttct tccaaatagg tgttcattac accaaacata
     6901 aaataaaggt aagcttgctc tgttggagtg atgtgattca tcgaccagaa gtttgcttca
     6961 aaaaaaggct ctagtatgta atgcgtaaac tcttcttttg ttatcaatgg atgcacaaat
     7021 ttgttcatct cttctgggac atacgtaatc gagtggcctt gtttcattcg ttgcaacgaa
     7081 attcttagta ggctgatcca tttctttcta tctatactac gcgtatatgg cgcatgtttc
     7141 gcaaattttt ctaatagttg acgtttattt tttatacttg ataatatatc agaatgattt
     7201 tcgtcgaatg actgccaata catcaagtga aaaaagtatc ggatacggta ttcttctcct
     7261 tctatcggat tacctttttt caagctgcaa gataaatgat agtttttcaa aatagtatta
     7321 agttctctta attttctttg aatcgtacgc aaacttatat aattttttga ctaagatttt
     7381 ctaaggattg ataagtacct ttgtaaagtg aatccagtaa aatataacca atcgttccct
     7441 ctaaaagtat agaataaact ttactcagta aaaactgaga agaaaactcg acttttatca
     7501 tcttgttttc tgaaagaaaa gataatttat attctggata cctttcgcaa aacgattctg
     7561 cttgttgaat caccgaattc atcttagcca gggtgtagtt tagatctaaa gcgatatcct
     7621 tcaccacata taatttctcg tctctttcat aacaatagtt caaaaattga tatacttgcc
     7681 tttcattgat atcaataaat tcttcaaaca aagtacatac tcctttttat ctattattta
     7741 gacttattcc gacagctaca tgaataacgt acaaatagat tcgttactga tttttcagag
     7801 atactaccat gcgcagtgtg cattgtcaat tattcttgct cttattttcc atttgtgttc
     7861 ctgttatttc ctgtttctca aatatgttag taaacaaaaa tagatctggc aaagctacaa
     7921 cttcgccagg caatacagca ctctcgaatg aaatattcac tcaaaaatct atcgttttat
     7981 tcaattttag at
//
LOCUS       DAZKPE010000096         7754 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000096 DAZKPE010000000
VERSION     DAZKPE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.097"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(69..1490)
                     /gene="tyrP"
                     /locus_tag="ACG930_002606"
     CDS             complement(69..1490)
                     /gene="tyrP"
                     /locus_tag="ACG930_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFQ0519725.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="ACG930_002607"
     CDS             complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="ACG930_002607"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFQ0519726.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3901..5157)
                     /gene="tyrS"
                     /locus_tag="ACG930_002608"
     CDS             complement(3901..5157)
                     /gene="tyrS"
                     /locus_tag="ACG930_002608"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFQ0519727.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5269..5474)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5737..7038
                     /locus_tag="ACG930_002609"
     CDS             5737..7038
                     /locus_tag="ACG930_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0519728.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7107..7706)
                     /locus_tag="ACG930_002610"
     CDS             complement(7107..7706)
                     /locus_tag="ACG930_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0519729.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         2299 a         1589 c         1360 g         2506 t
ORIGIN      
        1 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
       61 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
      121 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
      181 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
      241 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
      301 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
      361 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
      421 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
      481 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
      541 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
      601 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
      661 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
      721 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
      781 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
      841 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
      901 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
      961 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
     1021 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
     1081 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
     1141 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
     1201 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
     1261 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg
     1321 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
     1381 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
     1441 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
     1501 ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca ataaacgaaa
     1561 caattcagcg aatatttgag gggattcttt gagtttattg cttgaagggt ttcttcaaag
     1621 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
     1681 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
     1741 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
     1801 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
     1861 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag aatcctagtt
     1921 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
     1981 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
     2041 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acatagtcta
     2101 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
     2161 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
     2221 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
     2281 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
     2341 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
     2401 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
     2461 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
     2521 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
     2581 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
     2641 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
     2701 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
     2761 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
     2821 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
     2881 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
     2941 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
     3001 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
     3061 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
     3121 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
     3181 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
     3241 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
     3301 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
     3361 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
     3421 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
     3481 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
     3541 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
     3601 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
     3661 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
     3721 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
     3781 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
     3841 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
     3901 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
     3961 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
     4021 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
     4081 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
     4141 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
     4201 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
     4261 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
     4321 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
     4381 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
     4441 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
     4501 tgggatcgtt aaaccgaacg cttctgcttc tggtccttct aattttcgga ttaggtctaa
     4561 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
     4621 tttatgcaga tgcaaaaagt cgatagattg caggatttgg taagtaaact ctgtaaatga
     4681 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
     4741 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
     4801 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
     4861 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
     4921 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
     4981 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
     5041 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
     5101 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
     5161 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
     5221 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
     5281 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
     5341 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
     5401 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
     5461 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
     5521 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
     5581 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
     5641 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
     5701 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
     5761 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
     5821 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
     5881 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
     5941 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
     6001 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
     6061 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
     6121 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
     6181 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt tgaatgattt gatccaaaaa
     6241 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
     6301 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
     6361 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
     6421 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
     6481 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
     6541 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
     6601 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
     6661 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
     6721 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
     6781 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
     6841 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
     6901 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
     6961 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
     7021 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
     7081 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
     7141 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
     7201 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
     7261 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
     7321 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
     7381 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
     7441 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
     7501 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
     7561 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
     7621 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
     7681 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
     7741 tatatatagt tcaa
//
LOCUS       DAZKPE010000097         7751 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000097 DAZKPE010000000
VERSION     DAZKPE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.098"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(13..348)
                     /locus_tag="ACG930_002611"
     CDS             complement(13..348)
                     /locus_tag="ACG930_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFQ0519730.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(332..595)
                     /locus_tag="ACG930_002612"
     CDS             complement(332..595)
                     /locus_tag="ACG930_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFQ0519731.1"
                     /translation="MAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQGKI
                     PFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(1055..1858)
                     /locus_tag="ACG930_002613"
     CDS             complement(1055..1858)
                     /locus_tag="ACG930_002613"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFQ0519732.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(1836..2960)
                     /locus_tag="ACG930_002614"
     CDS             complement(1836..2960)
                     /locus_tag="ACG930_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519733.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(2976..3791)
                     /locus_tag="ACG930_002615"
     CDS             complement(2976..3791)
                     /locus_tag="ACG930_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0519734.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(3781..4653)
                     /locus_tag="ACG930_002616"
     CDS             complement(3781..4653)
                     /locus_tag="ACG930_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013669610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFQ0519735.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(4738..6027)
                     /locus_tag="ACG930_002617"
     CDS             complement(4738..6027)
                     /locus_tag="ACG930_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFQ0519736.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKITKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(6171..6683)
                     /locus_tag="ACG930_002618"
     CDS             complement(6171..6683)
                     /locus_tag="ACG930_002618"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519737.1"
                     /translation="MTINCDLKEEGLEMAVFSLAQTYQIWPQIVLSGYVQLSWAAIWG
                     KHIFYNIENQFEGKKLGDITEADLIDTLQKLAYQSVQIVNIHEGWLTKLAREVGQQLG
                     LTFSVWTVNELETIEYLARCGVYNITSRCAWAYLWKKGAQNKLFYNQNRGVKRFGDGI
                     HDHMGALFLA"
     gene            complement(6750..6893)
                     /locus_tag="ACG930_002619"
     CDS             complement(6750..6893)
                     /locus_tag="ACG930_002619"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFQ0519738.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
     gene            complement(7376..>7751)
                     /locus_tag="ACG930_002620"
     CDS             complement(7376..>7751)
                     /locus_tag="ACG930_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0519739.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSLEQLLSTVWLSVRTAFFVG"
BASE COUNT         2366 a         1672 c         1192 g         2521 t
ORIGIN      
        1 tttttagtat tattataatt cttccatgcg ttcttccagt cgctgtaaat cgcttggact
       61 taattcccca atttttttcc atttgacctt tttgttgttt ttgggtaatt cgtttagagt
      121 tcctacgtca atccaagatt ctttttttag tcctgcctgt ttccaatccc ttatttcaac
      181 gtatttcagc tttattttat cggatttagt atgatatttt gaagtaattg acagaaacga
      241 aattgtgtcc agtccatttt ttagaatata gacaggccgg cgtttaccgc cctctgcagc
      301 tgtgaaagca acgtagacgg ttgctatatc attagtattc atcttcattg aaccactctt
      361 caattttttc gtcagtgtct agtttttgga caggcaattt ttccgctaat ctttgaatat
      421 tatggattcg tttacttttt tccgacaatt caatagaaaa tgggattttt ccttgctcaa
      481 caatttgctt ataaaaaacg gtgacggctg ttttggggct catgcctagt tcatcaataa
      541 tgctttctgc ttcatttttc aatttttcgt ccatagaaat ttgtaactta gccattttct
      601 ccacctcttt ctgacaaaca cattatatca cggaaagagt tcaaatggaa ttaatacaac
      661 tacttttgaa ctccttgaaa tgcagtgtat ttatctaaat ataaggaaag gatatagtgc
      721 taaatggcct tgatagatag aaaagtttca aaatccgcca cagcgataat tgaagcgaac
      781 actcaacgac acacagaaca ggaaaagact cctaaaagaa ccaaattaac taggacgtgt
      841 ctgaaaactc cacaaagatg tggtatgctc tggtaaaaaa cgaatggcac aaccacgaag
      901 accgatatgg ttcttggaaa actttctcca ccctttttgt aattggaggg atagtggttt
      961 attgatagcg attttccaag ttcttcaagt ggaaccagac attgagcacc acggctaaaa
     1021 agtgaatgaa gtctttattt ttaatcaata atttttaatg attaccagta attggttttt
     1081 tcatgcgccc tatttctatt tgatgtggag ttaaataatg ctgataagta aaaatttttc
     1141 cgtcaattaa actgccacta gtgaatcctg ttctattggt aaaaagagaa tagtctgggt
     1201 attcatctac accaaatgat aaagattcag ccataaactg ttttttacca gcaaattcag
     1261 cactgctacc ttgatggata tggcctacaa aaatacctaa aatatcactt tcggcaatca
     1321 attcagcaaa accttccgga acttcagtta caatagatgg atcttcccac gacaatggat
     1381 gatgaaccaa taaaatcgtt cccttttcag caggtgtacc caaccactct tgtaattgaa
     1441 tcatctgtcc tatcgatatt tttccttcgt gctgggtatc ttgagcagaa tccaaggaaa
     1501 taattcgtaa cccattttga ttcgtacaat ggatatactc tcccgtttca ttgctttcaa
     1561 cactcattcc ttcaaagaaa acactgcgac gatcatgatt cccacgacaa aaatagtaag
     1621 gtgtggttgg gaaatattga tccaacattt tccgtaagac ttgataatca gaaatccccc
     1681 cttcatgtac taaatcacct gttaatagaa taaaatcgta cactgttaac gagagttctt
     1741 gtaacaattt ttccaatgcc aactgtggat ttttaattgt tggaaatagt tcagcagtaa
     1801 acaagttagt ttgatagttt tctctaaaat ggatatcaga gagatgcaaa aagcgcatgg
     1861 ctattccctc tttcttcaat aaaataatca ggatatccta aattttcttg cgtctgataa
     1921 tcaaaaaaat gcattctttc aggttctatg cggagattga ctgcatcacc aatctgccaa
     1981 gtaggttttt cattaaggac aatcatttct ataccatcga ctttaacggt gtacgcataa
     2041 ctttgaccta atagctcacg atacttcact tgaccgtgta aatcgcttgt ttcttttgaa
     2101 aaggttacgt gttctggtct tatgcctaaa tacaatgagc cactaacctg aagaagttgt
     2161 ttttgccaag ctggattcaa tgttaaaaat tgactggcta cctttaatgt tccttgatca
     2221 taagtaactg gcataatatt catgcctggc gaaccaataa aatttgcagt aaaagtattt
     2281 ttaggtttcg tataaacatt tttcggcgta tcaatcatct gaattctacc ttcattcaat
     2341 aaaacaatcc ggtcagctaa cgtcatcgct tcaatttgat catgagtgac gtagacaaaa
     2401 gtttgtttat aacgttgatg aatttttacc aattcttttc gtgcatccaa tcgtaaacgc
     2461 acatccaaat ttgataacgg ttcatctaat aaaaaataat tactccgttt aaccaccgca
     2521 cgagccaatg ctacacgctg ccgttgccct cctgacaaat ctttaggaag tcgatcttgg
     2581 tatggcgtta aacctaacat cttcaaagct tcttccaaac ggtgctgaat gtcagctgtc
     2641 ttaattttat tcgcccttaa tgcaaaaata atattctcct ttacagtcat gtgaggatat
     2701 aaagcataat tttgaaaaac cattgcgatc tctcgttctc cacaaggtag cttatttgct
     2761 agttgtgtac ctaaaaaaag ctctccactc gtaatttttt ccaaaccagc aatcattctc
     2821 agcaaagtag attttcctga accagatggt cccagtaaca caattcgttc tccagcggcc
     2881 acagctaaat caatttcttt taaaatggta tgttctccat atttttttcc gatatttctt
     2941 aattcaagcg tttctcccat gatttgtcct ccaatttatt taatacctgc agaaacaaaa
     3001 gtcccgataa tatatttttg aaaaattgca tacaagacta acggtacaaa cattgtaatt
     3061 aaactaatcg ccattgctac ggtaaaattt gtcccacctt cagaactaat ataggtctgc
     3121 atcgccaacg gcaaagtata attatctact gtccgtaaaa ttaataccgg ccaaacatac
     3181 tcattccaag aggtaataaa aaaccaaata ccggtagaag taatcgcatg tctagtaaga
     3241 ggaaaaacaa ttttactcat gacggttgtt tgtttgatgt tatccaatgc cgccacatct
     3301 agaaggctca ctggaatttc ccgcattgtt tgcgtcaata aaaaaatgcc catcgcatca
     3361 gcaaattgtg gtattatcac accccaagta gtatcaatta aattaagttt tgcaatcaac
     3421 aaataattag gaatcatcgc aacagtaaaa ggaatgaaca tcgtaccaat gatgataaag
     3481 taccagattt tcttcccttt gattcggcaa taagtaaaac tatatgccgc aaaaaaagct
     3541 acgcctaact taacaaccgt tataattgta gcaataaaaa aagtatttct cgtaattttg
     3601 ataattggaa gattttcgaa caaatagcaa aaattttcca aggtaaacgg ctgtggtatc
     3661 aaactagtaa tcgtctgata ggcatctttc aatggcttaa aagaattggc cataataaac
     3721 aataatggat agataataat gattatgatg aacataaata agagatgtgg caaccagcgt
     3781 ttaattttca tagtaaaccc ccttttccac aaatttaaat attaccccta agaaaacagc
     3841 aaatattaat aaagttaaaa ctgaaattgc tgaagattct ccgactttat acatttcaaa
     3901 agccttttga taagcataat agatcacgtt tgcactacca ttattcggtc caccacgagt
     3961 gatgatctta atcggagtaa acacatactg cagaccttga acaatggtca tcaccaataa
     4021 atatagtcct gtcgaactac tcataggcaa cacaattgta aaaaaaatgc gccagatggg
     4081 tacacgatcc aacttagctg cttcgatcat ctcttgatca attcccacaa ttgctgcaaa
     4141 aatgacaatg aaattataac caaaaacttt ccaagcagta atacctgcaa tcacagcaat
     4201 tacccaacct tgtaaattca tccacatagg cagtcttaaa ccaaaatttc ccaacaagac
     4261 agcaattggt cccgataccg gatttaatat ccatgtaaaa accatccccg ccactaccaa
     4321 agaaatcaca gctggaataa aaaataatgg tttatacaaa ttctgccctt tttctataac
     4381 tattcctaat aaaaaggatg taatatatgg gaacacacag ctcagcaaga caaatagaac
     4441 ggtataggac aaagtattct tcaacacttt atgaaagact ggatcagtca gcacctttac
     4501 atagttggca aagccaacaa attctttagt gggggccacc atattccagt caaaaaaact
     4561 caaatagatc gtataaatca atggataaaa aacaaacacg cccaacaaaa taattgctgg
     4621 cgccagatac aaataaccta catagcgctt catttccgac agcctcctca tccttatgtc
     4681 aaaagcagac gaccttgttt ttcctttctt acaggcgctg tcgtctgctt gctttgctta
     4741 tttgagtaac tcattaattt ccttttgagt agctttcatc gtttcattga cggaattacc
     4801 tgataaaatt ttatcccgca tatccaacaa tttttgttca gcttctaatc cagcatctcc
     4861 aggaaatgaa ctccaactga ccatcttatc catctgatca attgctggta tcatcatctg
     4921 attttcagct aagaaagctt ttaatccatt ttgggcgtct gcaacatctt tacgtggtgg
     4981 taaataacca gtaccttctg tccatttagc taaagattca acactataaa gatattttaa
     5041 gaaatcccaa gttgcttcct ttttcttatc cgtttgtgat gtaacagcta acattgcgcc
     5101 accagcaggt agtttaactt ttttcccttc ccaacttggt gactcaactg ctttagcagt
     5161 aaaagtacta tttttttgaa tgttgtccct ttgagcaata gtggtataga ccatcgcgac
     5221 gttaccatca ataaagcttt gcacaccttg ttcccacgta gtgtgtaatg ccgtctggtc
     5281 ttttaccatc ctttgatata attcataagc agcgatacca tctttagaag caaaggtagc
     5341 tttgccatct tttattacac ttgccccatt actttctaaa attgcttgtt gtgcccaatt
     5401 atcagcaggt tcttgaatat acacgccata ctttccagtt ttttctttta ttatcttaga
     5461 aaaagtttga acttcttccc aagtttttgg accattttca tccaagcccg ctgcttttaa
     5521 tatatcttga tttaaatata aaaccggatt actaatggag taaggaatac ccacttgttt
     5581 accatctttt tcagacagtg ccatgatatt gtctaaaaaa tgatctttaa aataatcagc
     5641 attatccgga tccacttctt ctactaaaga ttgaggatta gtatatttga aattttctgc
     5701 aaaataatct ttaaaagccc atcccacttg tactacgtcc ggtatttctt tggaggcaac
     5761 agaagcttgt aaattttgca tcaagccttt atacatatca ggattatatt ttgctacaac
     5821 cttcactttg tcttgagatt gattgtattt atctactaat tcattcactg tttttccacc
     5881 tagggtatcc gcattaacat gccaatactc tatcgttaca cgaccctccg atttttttgt
     5941 tatcttggta ttcccactac cacaagctgc caaagagatg acacttaaaa cagacacaac
     6001 ccctataaca agatttttct ttaacataac attaacttcc tcctaatttc tttatggcca
     6061 tttttctaat caagaaatat tatgaactac caatgtaaat ttctagttaa ttttctgtaa
     6121 ataattcgaa atttgtgcat ttcggggtac agggtcactg gacatatcca tcaagctaag
     6181 aataaagccc ccatatggtc atgtatccca tctccaaatc tcttaactcc tctgttttga
     6241 ttataaaata gtttattctg tgctcctttc ttccataaat aggcccatgc acaacgtgag
     6301 gttatattat aaacaccaca gcgcgcaagg tactcaatcg tttctagttc attgactgtc
     6361 catacagaaa atgtcaatcc tagctgctgc cccacttcac gggccaactt agttaaccat
     6421 ccttcatgaa tattgacgat ttgaacgctt tgataggcta atttctgtaa ggtatcgatc
     6481 aaatctgctt cggtaatatc cccaagtttt ttcccttcga actgattttc aatattataa
     6541 aatatatgct ttccccaaat cgcagcccaa gataattgta catagccact aagaacaatt
     6601 tgtggccaga tttgataggt ttgtgccagc gaaaaaacgg ccatttccaa tccctcttct
     6661 tttaaatcac agttaatggt catggttgcc ttctcattgg ccactgcttg aaacacctgc
     6721 tcaagggtta ccgaatctgg gacaacttct tacctgtcat gggctagtat tagcgtacca
     6781 tctgtttgct gacgcacatc tacttcaaaa caaagctggc gatccaaaca aaagcgaaga
     6841 aatgcccagc tattctcctc cgtattgtca ctaccagagt gtgcagtgat catggtcatt
     6901 ttgacccctc ctttaattcc gtgattttct cccacacgtc cactataccg atgaagcgtt
     6961 aatttcttgt taatttcttg taaattccct gcgttttttc agtaaactag ttgtaaatct
     7021 tgcatgctcc ttcctacgaa ctcatgaatc gtcgattttg cccttctagc tagtttcacc
     7081 aattaagtag ttctacattc cccgctttta acctactaca cctttttttg ttttcagcta
     7141 ttccttcttc ttgctgaaag tccttgaggt tctttcttac aggataccat caaggtgttc
     7201 aatggcttat tcccattgaa tgaccgagac ttactatcag atttctgctc gttgaaccaa
     7261 gtctttgata caggatttct tccgtcatct tctcacaaat accaccttgc gtttctctag
     7321 cgattggtcg atgtgcaccc tcccagtgga ctgtcactac ccctttttgc tatgcctagc
     7381 ccacaaaaaa agctgtcctc acagacagcc agactgtaga caaaagctgt tccaaactcg
     7441 taactcgagc ttggaatagc tttttatcta cttcgtttcg aatttttgaa caaaaaaata
     7501 aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt gcagcaaaca
     7561 ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa cgcatcccat
     7621 gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt ttgtaaattg
     7681 atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct ccccaaacat
     7741 gtctcgtgat g
//
LOCUS       DAZKPE010000098         7743 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000098 DAZKPE010000000
VERSION     DAZKPE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.099"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..325
                     /locus_tag="ACG930_002621"
     CDS             <1..325
                     /locus_tag="ACG930_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519740.1"
                     /translation="STTLKGKFMERSSHAMILTFLWLLFTRIYIFLMSLKPPKSISLC
                     LVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIGYFPNKNNNFYF
                     YRNKL"
     gene            complement(451..1128)
                     /gene="nth"
                     /locus_tag="ACG930_002622"
     CDS             complement(451..1128)
                     /gene="nth"
                     /locus_tag="ACG930_002622"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFQ0519741.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1135..1833)
                     /locus_tag="ACG930_002623"
     CDS             complement(1135..1833)
                     /locus_tag="ACG930_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFQ0519742.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2101..3285
                     /locus_tag="ACG930_002624"
     CDS             2101..3285
                     /locus_tag="ACG930_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFQ0519743.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3291..3734)
                     /locus_tag="ACG930_002625"
     CDS             complement(3291..3734)
                     /locus_tag="ACG930_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFQ0519744.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(3960..4247)
                     /locus_tag="ACG930_002626"
     CDS             complement(3960..4247)
                     /locus_tag="ACG930_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0519745.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4418..5770)
                     /locus_tag="ACG930_002627"
     CDS             complement(4418..5770)
                     /locus_tag="ACG930_002627"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFQ0519746.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            complement(6042..6488)
                     /locus_tag="ACG930_002628"
     CDS             complement(6042..6488)
                     /locus_tag="ACG930_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFQ0519747.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6724..7650)
                     /gene="cysK"
                     /locus_tag="ACG930_002629"
     CDS             complement(6724..7650)
                     /gene="cysK"
                     /locus_tag="ACG930_002629"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFQ0519748.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
BASE COUNT         2092 a         1578 c         1267 g         2806 t
ORIGIN      
        1 aagcactact cttaaaggaa aatttatgga aagaagctct catgcaatga ttctcacttt
       61 tttatggttg ttgttcacca gaatctatat ttttctgatg agcctgaaac cgcccaaatc
      121 cattagttta tgtttagtta taaatggtat ttttttatta tcacttatca tttttattac
      181 acctttagat agatacgtca cttatttata taatcctttg gaatactgga cttattttat
      241 aggtatattg gaaggcatta ttttctacat cgggtatttt cccaataaaa ataacaactt
      301 ttatttttat cgcaataaat tgtaataagt taccatccta gctactgagt atgtacattt
      361 actttttcat gcaaaaaaga taaacgaaac agcttttctc cataataaca agataattca
      421 tacatttatt tgcaattaaa gaaaccacgt ctacaggcgt ggtttctttt ttagcgcctt
      481 ttcttttaga cgcatccgat ttttcccatc ttgacatatt gatagcaaag gacatacctc
      541 gcacttggga tttcttgccg tgcaatgata tctaccaaaa aaaatcagtg tatgatgtgt
      601 ctttacccat aattcttgtg gtactttccg catcagtgtt tcttctactt ccatgaccgt
      661 agcatctagt ttgcagatcc tcaggcgttt tgagacacgt tccacgtggg tatctactgc
      721 gattgctggt atcccgaatg catcccccaa tacgacattt gctgtctttc tgcctacacc
      781 aggaagagac atcaattctt ctcttgacgt tggcacttgc ccatcgaaac gttcaatcag
      841 ctgctgtgca cacgctttga tgttttttgc tttatttcga tacaaaccaa tcgtttttat
      901 tttaagaatg atttcatcga ttgaagcttc tgctaacgca tcgggtgtcg gaaaagaggc
      961 aaacaaatct ggcgttgctt tattcactga tacatctgtc gcctgggcac ttaagatcac
     1021 tgcaatcaat aactcaaatg gattattgtg cttgagttct ccatgtgctt cgggaaacat
     1081 tccatacatc gtttctagag cttccattgt tttttgtttg cttaacatat tccgctactc
     1141 ctccaaccaa tttttcagtg agactttcgg caattcttct tgttgagctg actgttctac
     1201 ttctctttga agaagctgct gttttcttcg tttttggtct tcttccactt gttgttttgt
     1261 acgtagattt tttctttccc acgatagcaa aatgcggtca acgtaattaa aactataagc
     1321 ctgatttaat acggcttccc gcagtgctag cttcaaaatt tccggctgat aatggtcttc
     1381 ttctagccat tgtccgatcc gctggaactc gatcgaagaa agcgggcgtc caaattcttg
     1441 ttcaaataat tgatacactg actggatttc tttttcttgt gttttttctt cgtatttttt
     1501 ttcttgtgtt tttaaatact cacctaatag atcatagatg gggtaaagat tatatcgatc
     1561 tgctttttta ccgttgacaa tcgtcgtttc tatcttgata aatccatttg ttacgagacg
     1621 atccagtatt tgaaaaatct gatcttgttt gattcccata tccatagcaa tcatctgcaa
     1681 atcagggaaa gtatctcctt caagctgtgc catatgcaac tgtagaacaa ataaaaattc
     1741 ttcagattgt agaccgatcc tatgataatt tttaagtaaa agattagata tgactgtttg
     1801 tccagcgctt aagtaatttt ctaaattcaa catgatttct cctccgctca atcacagtat
     1861 acgtaaaaaa aacatgggaa gcaagaacag gtttcttttc tatttacttc actgatcggt
     1921 cagatttaca atgtcgtcta cttgattttt gtttgttcat gtttttgatg cgtatcttca
     1981 cttttcggaa taaataaatt aagtagattt cgctgttcct tagaatgttg acaaggaaac
     2041 aaaattacta tacactattt ttgtttccaa gttaacatta ttgcataaag gagtttttac
     2101 atgtacagtt tcacaaataa acattctaaa gtttttggat acgtctctgt cttattcact
     2161 ggattaggat ttactatcgt cagtcctgta cttccgtttt taacgctgcc ttattctcac
     2221 tccatacatc agcaagcttt ctatatcact ttgctcatgt ctgtttatgc tctagctgcc
     2281 ttcttatctg cccccattct cggtagctta agtgatcatt ttgggcgtca tccgatcctt
     2341 attatcagtt tattaggatc aagtatcgga tatttgcttt ttggtttagg aaattcgata
     2401 tggatgttgt tccttggtcg tatcattgaa ggattgacgg caggagaaat ctccacctta
     2461 tatgcttact ttgccgacat cacggaacct aatgaaagaa ccaaagtttt tggatggatg
     2521 ggtgctttag tcggtatagg aacaacgctg ggtcctatta tagggggtct attagctgag
     2581 ttggggaatt ctgttcctat atttattgga gcactcttta ctttcttaaa tgccgtttat
     2641 ggctacacat ttatgctaga aagccttcca ataaaaaaac gttcagtaga tttaagtttc
     2701 tcccatgtaa gaccttttca ccaattacaa caattattca agatttcatc cgttattcct
     2761 ttattgacag caggttttgc tgtttggttg gcagctggct ctcttcaatc tatcttttct
     2821 caattttcga ttgacgcctt tcagtggaag gctgggttgg ttggtttaag cttctctttg
     2881 attggaatct tggatactgt ctcgcaattg ttcattatgc ctcgattgct caaaaaattt
     2941 tcagaacagc agatcacaag aatagggatg ttcagtgaaa tcctcgccta tctattcatc
     3001 acattatctg gaattcttct actgccgatt ttgtttttat ttgggattat ctgttatggt
     3061 ttcggtgatt ctatttttac tcctgtattc aatggccaac tatccaattc tgtctcagat
     3121 aaccagcaag gtcttgtaat gggcggtacc caaagtatac aatctctatc gcgcgtcatc
     3181 ggcccgctaa tcgcaggaca gctttatgct gcagcaccat ttcttccgac ggtattcgga
     3241 tttttgctta tgatttttgc ctattatcac tacaataaaa aatagtagct tcatttgcta
     3301 cttcgtataa attctctgta tcgaccgata aaacgaaata ctgtgtcaaa ttcttctttt
     3361 gacatatttt caaatacagt agcatctcgc tgtacccatt tttgatggag ttgctcgtgt
     3421 ctattcctta ttttttgtcc gattggcgtc aattgaaaat agatttcttt tttattctct
     3481 tcgctttgat aagtgtttat gatccctcta gctatcagtt tttttgttag cttactgatg
     3541 gctcctctag tcatgtaact agcattcgct aattttgtca cgttaggatc agggattttc
     3601 ccgatatgtt caatcacttc tagttcattt agagtaaatc ctgcaaattc tttttccatt
     3661 tctggtttat tacgatgaat aatctcatta gctaaatcca gatattcttc tattagcagt
     3721 tgtcttttat ccatttctac accttctttt tctttcatta tattgttttt ttgtttccta
     3781 ttcaacaaag ataaaaatat tttgtaggaa aacccaatct gaaaccaaga aaaaaagggg
     3841 ttgacaaagc ttgtcataac ccctttttct gattaaaaga tagtaaagag acagtcatcg
     3901 gtaattgtga tgattttttg tcatcactta aggatgagcg gccttttcaa aaactgtctt
     3961 taaagatcat catcagtttc tagcacatat ggctgacctt catatgtgta ctctgtattc
     4021 aatgtgccgt cattttcatc tgagtagatg cgtctactga aaggaaaacg atgagaaaca
     4081 ttatctttgg cgtcatttgc tggcatcgtg taatattcct cttgcgtttc attcaactga
     4141 gagagtactt gatctgccaa ctcatcaata ttgatcgtta atttcttcga agcactttta
     4201 taatcttcta aaaatgcatc ttgttggaca aaatattctt tattcatctt ctttctcacc
     4261 tttcttttca aaatcaaata aagctgcttg ttcttttatg taacagcttt atctttgctg
     4321 cttattgtga caaaaaattc gaagaaagac aactaattgt acttttcaca aaaaaagaca
     4381 gagggtcgtg acaaaattgt gtcacaaccc tttttcttta ttgtgcagtt tcgatttcgc
     4441 ctagcgcttc ttgtgcaagt aggttcaagt aattccatgg gcggtcaaaa tgtggttgga
     4501 agaagaaatc tgaaagtgcg agatcttcta cagtcatttt attttgaaca gctaaagaca
     4561 tggtatttgc tgattgtgta atgtcgtatt tggacatgaa ctgagcacct acgatacgat
     4621 tcgttccttt ttcatagact agctccatca ttactttttc agtagttggc atgaactctg
     4681 gacgataatt atcttcaaat acagtcgctt ggacttctag atcgttcaaa gttgcgcttt
     4741 ctttggtcac acctgtcgaa ccgatcgtcc agccaaatag gtaaagtcct gaagttcctt
     4801 gagtaccacg atacgccatt ttatgatctg tcaagttatt tcccacaagt aaaccttgac
     4861 gaacggcatt tgttgccaaa ggaatatagt tttgcgtgcc acttggattg tagttgacta
     4921 ctgcagagtc tccagctgca aaaatgtctg gatcacttgt ctgcatgtat tcattcactt
     4981 tgattgcccc gtttggcagt gtatctactt ttccttcgat cagttttgta tttggacgga
     5041 agcccacaca taaaatgacc atatctgtat caaatgtatc tgttggtgta gctacttgtt
     5101 tcacttttcc ttcttcatct gtgataaatt cagtaacatt ttcgcctagc gcaagagtaa
     5161 caccgcggtc tgtcaattct ttttctaaga tatctgtgaa tggtttatct agatatttat
     5221 tcaagatgcg atctaatcca tcaatcaatg tcacttgttt tccagattcg acaaaagctt
     5281 ctactaattc aataccgata tatccaccac caacaattac tacacgtttt gcttctttcg
     5341 cttgtgcaat aatttcattt gcttgattgt agtttttgca taggagtaca tttttcgcat
     5401 cgattccact aatcggtggg ataataggcc atgaaccagt tgtcatcact aatttatcat
     5461 aagaaaccgt ttctgtttct cctgttttca gatcttttgc cgttactgtt ttattttctg
     5521 tatcgacgtc tgttacatcg tgttccattt taactgttgc tcctaatgaa gataattctt
     5581 caggatttga gtagaacaag cctgctgggt cctttactac tccgccgaca taaagtgcga
     5641 taccgcaaga taagaaagaa atattgtcat ttctttcata tactgtcact tctgcttctg
     5701 gatgattttt taaaatactt tttacagctg cagtacctgc atgagtacag ccaattacta
     5761 ctactttcat ttatggtccc tccgattaac attttgtcct tcgacaaaac tactataaca
     5821 gaaataaaac ggatacaaca gtttaatgct tgtgaattca caaaggtttg tttgtagttt
     5881 cattcctttt caagcataag aacccaatat ctacaagatt cttattgtga taatattcac
     5941 tttgatatct aagattgtga ataaaagaca aaaaaataaa aaagctagcg tttttttaca
     6001 cagctagctt tttttaggta taacacttat agaaactgtt tttacatttg cgcctttttt
     6061 gctgactctt tacaatccgg acagagtcca tacaattcca accgatgttc attaatctca
     6121 aaatcagtca gtctgctcgc agccatttct atatcttcaa gccctgggta atgaaaatca
     6181 acaatcttac cgcagttttc acaaattaca tgataatgac gctttgaact gaaatcaaat
     6241 cggctagaag catcgccgta cttcatttct tgaacaaatc caatcgaagt aaataagcga
     6301 aggttattgt aaacagtcgc aacactcata tttggaaacc gatgttcaag tgctttataa
     6361 atctcatcag ccgttggatg ggaatgatgt tcaatcaaat attctaaaac cgcgtaccgt
     6421 tgaggtgtga ttcgaatgtt ctcttttttt aacttttcga taacctcttc gactaactta
     6481 ttttccatgt aaacacccca cgttgttatt ctcgtcttat catactattt ttacatttta
     6541 aaatccactt aacatgaaaa gaaaattcaa ttttattgta ttttaatgaa aaaagacgta
     6601 aaacagtcgc gttcactatt ttacgtctct attcaaataa tttttctcat cataaatttt
     6661 tgtgtgttct tttcatcttt aaaagttttt tacataaacc tatctggaga aaaaccaagt
     6721 gccttatatc tcttggtaaa gggctgtaga taaataacgt tcaccattgt cgggaaccac
     6781 agctaatacc ttcttgcctt ttcctaattc ttttgcgact tttagcgcgg cagcaattgc
     6841 agcgccagat gagatgccta ctaaaatccc ttcttttcgc ccaacttctc tagctgtttc
     6901 catcgcttcg tctccactaa tagaaaggac tttatcatac acagaagtat ccagtgtttt
     6961 aggaacaaaa cctgtaccga ttccttggat tttgtgaggt cccgcttctt tcccttctaa
     7021 aatagcagat tctgctggtt ctaccccgat taattcgatt ttcggataca cacgttttaa
     7081 ttctcggcca gcgccagtga tcgttcctcc tgtaccgata cctgcaacaa acgcgtccaa
     7141 gccatttact ccaaatgctt gatgtatctc aggaccagtc gtcttctcat gcacaagagg
     7201 atttgcttca ttttcaaatt gtaatggtaa aaagtagccg ttttcttttg ccaaacgttc
     7261 tgcttctctg attgatccag aaataccatc cgcaccagga gtcaaaatca actctgcgcc
     7321 gtaccctttc atcaataaac gtctttcgat actcatcgtc tcaggcatca cgatgattac
     7381 tttatatcct tttgcaactc ctaccatcga caatccgatt cctgtatttc cagaagtagg
     7441 ttcaatgata gtatcacctg gtttcagtag accatcgtgt tctgcttttt ctatcatact
     7501 taaagcaata cgatctttta cacttcctcc tggattaaaa aactcaagct ttacaaaaac
     7561 atctgctgaa tcttctggta cgattttatt taatttgacg attggcgttt tgccaatcaa
     7621 ttcggtgact gagttataga tagctgtcat cttcaattcc tccttgtctt tgctcttctt
     7681 acttatcata atacaatctg ttcatttatg gcgagtgatt cgtctttgac tagcaaaaaa
     7741 aag
//
LOCUS       DAZKPE010000099         7627 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000099 DAZKPE010000000
VERSION     DAZKPE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.100"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(16..714)
                     /locus_tag="ACG930_002630"
                     /pseudo
     CDS             complement(16..714)
                     /locus_tag="ACG930_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            793..969
                     /locus_tag="ACG930_002631"
                     /pseudo
     CDS             793..969
                     /locus_tag="ACG930_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1145..1714)
                     /locus_tag="ACG930_002632"
     CDS             complement(1145..1714)
                     /locus_tag="ACG930_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0519749.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="ACG930_002633"
     CDS             complement(1788..2111)
                     /locus_tag="ACG930_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519750.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="ACG930_002634"
     CDS             complement(2265..3077)
                     /locus_tag="ACG930_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519751.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3404..4279
                     /locus_tag="ACG930_002635"
     CDS             3404..4279
                     /locus_tag="ACG930_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0519752.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4293..4616
                     /locus_tag="ACG930_002636"
     CDS             4293..4616
                     /locus_tag="ACG930_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519753.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4613..5365
                     /locus_tag="ACG930_002637"
     CDS             4613..5365
                     /locus_tag="ACG930_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFQ0519754.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="ACG930_002638"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="ACG930_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1372 g         2470 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 aacttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggtttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgagaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg aatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccaaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcatataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctcgaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaacct
//
LOCUS       DAZKPE010000100         7519 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000100 DAZKPE010000000
VERSION     DAZKPE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.101"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(56..346)
                     /locus_tag="ACG930_002639"
     CDS             complement(56..346)
                     /locus_tag="ACG930_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519755.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(464..724)
                     /locus_tag="ACG930_002640"
     CDS             complement(464..724)
                     /locus_tag="ACG930_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519756.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(861..1274)
                     /locus_tag="ACG930_002641"
     CDS             complement(861..1274)
                     /locus_tag="ACG930_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFQ0519757.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1730..2215)
                     /locus_tag="ACG930_002642"
     CDS             complement(1730..2215)
                     /locus_tag="ACG930_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519758.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2354..2569)
                     /locus_tag="ACG930_002643"
     CDS             complement(2354..2569)
                     /locus_tag="ACG930_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFQ0519759.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2793..3593
                     /locus_tag="ACG930_002644"
     CDS             2793..3593
                     /locus_tag="ACG930_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFQ0519760.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3612..5480
                     /locus_tag="ACG930_002645"
     CDS             3612..5480
                     /locus_tag="ACG930_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFQ0519761.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5473..5964
                     /locus_tag="ACG930_002646"
     CDS             5473..5964
                     /locus_tag="ACG930_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFQ0519762.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            5952..6506
                     /locus_tag="ACG930_002647"
     CDS             5952..6506
                     /locus_tag="ACG930_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFQ0519763.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6524..7519
                     /locus_tag="ACG930_002648"
     CDS             6524..7519
                     /locus_tag="ACG930_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFQ0519764.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2673 a         1204 c         1432 g         2210 t
ORIGIN      
        1 ctttcaaaaa tatgttttgg aagttgggac aaacgagtta atacatttta atacattatt
       61 ttttattcaa aaaaaatagc acaatggcaa agatcgtaag agagatcata agccccaatg
      121 aatgactaaa aagaaaagca gaatcacatg ccatatcatc ccatatttct tcaagaaaat
      181 aaataagcgg gaaaaaggga aggaatagta gaacatcgat ccagcaccat ttttttcttc
      241 ttttgaaata acataaaaca ataaacatga acgtgcaggg aagtaaaaac aaagctttac
      301 tcataactaa caaaatacca gctcctttta tttttttctc ccccacattc aaagagtaac
      361 aatggtatgt acttaataat agaaaaatgg atcaacttgt atgaataaca gctgaaaaga
      421 tctgcaccaa ataaaaaact tccagccaaa actgactgga agtttatttt tttctgaaat
      481 attctaacac aaatatgaaa aagatggccg aagctaataa gccgatttcg tagcaaaaca
      541 atgagatacc agagtcgtaa taataaaatc ctctaatctt atggataaaa tagatcatcg
      601 gacaagcaga taagagtaag tatttgttag gccttttgaa taagtaaaag aaagcactgg
      661 tcattatgat aaatggtatc caaaacaaaa gtttacttaa gacaatcaaa tgatcaactc
      721 ccatattttt taccaagaga gatcataaca tctttatcgt aaaaacaaaa tatttttttg
      781 ctcattttga aaatttaaac atactcgttc ttatccaaat atataaaaat cgcccctcat
      841 tcatcgagag gcgataagtt ctaatttaac tcaatttttt ttgtttcttt tggctgataa
      901 gctgttttag gtaataccaa tttcagcaca ccgtttttaa aggttccagt gattttttct
      961 tcatcaacat taggaagata gaatgaacgt ttgtaagaga ccgaatgtct ttctttccgt
     1021 acatagttgc catcttcttt atcttctgta tgggactcat gattggcgga gatcgtcaaa
     1081 gtattatctg aatattcaac tgtcgtgtct tctttgtcac agccaggcat atcagcagtt
     1141 agtttgtatt ctttttcatt ttcgactaaa tctacttttg gataacttga aacacctaaa
     1201 aaatcattga atgctggact aaacacgtca ttgaaatcag ggaacatgtc gcgaatgcta
     1261 ggtacatttg ccatttttga tcatcctttc aataagtatt ttttatttat ccctatttac
     1321 gtaataactc tattttgaaa aaaatgcaag tataatggtt agctttgtga atatttcatc
     1381 taatacgata caaaggctat ctttctaatt tgaaaaaggg atcattaaaa taataagaag
     1441 aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca aatatagaaa aattgaatct
     1501 agaaaaccgc ccgacaataa atttcattaa ctcagttgac cgaaaatgaa gtagatacca
     1561 aaaatttatc aagagagcaa gtagagaagt gagtatattc ataagagaaa tagctgtaac
     1621 gaattattag gttaatgcaa atgcttattt atactccgta taactttctc agaaaaaatg
     1681 ataccaataa tgacttgcta gtactgtaaa tccgtataat atcatctaat caaaatggtg
     1741 ttccatttgc atctgtcatc gtaatcgatc cttcgggtga cactcgataa aaaccaacgc
     1801 ttccagatcc tccttgggaa cggatttgtt tgctggaagc tgtgaacaaa taatctcgat
     1861 caattttttg ataaaagcta ataacaatat cgtcactttg taattcggaa cggtgggcaa
     1921 taagaaatag aagtgctttg tcagagtttt ctaatggaag agaaggtaca gtgctttctt
     1981 gcatttcaga tgttgaagaa atgctaaacg actgaatact tgattggcta tgttgcgaat
     2041 ctacattacc agtagaagta ttagtaatgg aagtagtaga agtactttta gttgaaccaa
     2101 cctcagttgt tgaaatggct gctgaagatt ctttaacaga attctttgtt ttatatccac
     2161 aggcagaaaa aagtattaca gttcccaaca agcctgcgta aatcccttta tgcatgatag
     2221 ctcctcctaa aatagattat ctttattcag tatatcactt aaacaaagaa aagcagatgg
     2281 tttaaaatga aaaaaccttc ccaataaagg gaaggttcat gaagataata acttttttaa
     2341 taattatagc tttctaatat ctttcatcaa cttttctagt aatcattggg aaaaatttca
     2401 agcagtagat cgcacaaata cctacgacga tataaatgat cttcgcaaaa atagttgttg
     2461 aaccaccagc aatcatagct actaaatcaa gttcgaacaa gcctaccaac agccagttca
     2521 accctcccac aatcaataaa gttaatgcaa tagcatctaa agttttcatt agaattctcc
     2581 tttcttaaat gataaaacaa ttatatatca aaaagagaaa cattgcttat ataacgctca
     2641 ggaattttag caatctatgc aaaaagatga aaattttttt tgctcttcca ttagtacaca
     2701 ttttttagct gaagctgtaa atttcatgtc ttaatttttt ttagtgagct tttatactgg
     2761 atttgtaaga aaaaagaagg agaggatcac atatgtcgga ttggttggat attgcaggaa
     2821 aagtagtaat tgtaactgga ggttcctcag gaattggaag aagtatcgtc gaaaatttgt
     2881 tgaagcagaa tgcacaagta gcgaattttg atgtaactga atgccgtata cagcatgaaa
     2941 acctactatc tttaaaagtc gatgtgtctt ctaaaacgga catagaagaa gggatatata
     3001 aagtaatgaa acatttcaag acgatcgatg gtctagtcaa taatgcagga ataaatattc
     3061 cttctcttct aatagataga aatcatccaa aaagcaagta tgaattatca gaacaagttt
     3121 ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt gatgagccaa gcagttggaa
     3181 gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct ttcttctgaa tcaggattgg
     3241 aaggatcaga aggacagagc tgttatgctg ctacaaaagc agcgatgaac agttttactc
     3301 gttcttgggc aaaagagtta ggaaagagga atgttcgtgt ggtaggtgtt gcaccaggga
     3361 tactggaaga aaccggtttg agaacacaag aatatgaaga agctctttct tatacgagag
     3421 gtataagcgt cgaacagctg agaaacggtt acagtcgaac aagtacgatc cctctaggaa
     3481 ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta ttatctttca gaaagatcaa
     3541 gttatatcac tggagtcacg actaatattt caggaggtaa aacaagagga taaaggatag
     3601 gggggacgca cgtgacgcta gtaaacagat ggtaccaatt attgaaatta ctagtcactc
     3661 acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa aaccagtaat caaaccataa
     3721 aaaaagatat tggggagttg aatgaagaaa ttgccggtat tgcaaaaatc atccaaaaaa
     3781 acaaacattt tgaacttgaa atttatgatt ttgatttttt tgatgagatc atgcaaggaa
     3841 aattgaaaac agccagtgat ttcaattcgg catccaaaag aatcgcttat ttactaaata
     3901 ggctgatcga aacagaggat ttcttacgta tggatgattt gtctgaagaa gtcggtgtca
     3961 gcagaggaac agtggtcaag gatctaaaga cattaaaaga gatgatcaat gattttgatg
     4021 taaagattac aggcacacca aataaaggac taagaataat aggagatgag ctagaattac
     4081 gactactttt attttatttt gtttctccct acttttcaga gacgaaaaca gaacagtttc
     4141 tagaagaaaa acaagcaatc aaacattttc agaagaagac gaatgctagt aaacaagaaa
     4201 tcaccctttt aacgaaagtt atcggtattt ctttgaatag aatctctagt aactatctgt
     4261 tgaagaagcc catcaatcgt tacagtgggt gttttgaata tatccaagaa ttcaatgaac
     4321 tgatcaatca gttggaagaa atctatgaac taactttgag ccaatatgaa aaagatttta
     4381 tcagttttcc tttgaacatc atcaacacaa gtataacgat gataaggaaa gctaactctg
     4441 atttgcgctt atatttcgac cccatgatga tgcgtattcg acgattagat ctcattgatc
     4501 tggatgagtc cttcttatat caagagatga aacagcacct ctctttattg ataaatcggg
     4561 taatttttcg ttatcgattg actgatttat tttatggtga gatagaaaaa aagtatcctt
     4621 tttcttacca aatcgctagc gaatgcatac aagcattaga agctatcttg caacataaga
     4681 tctctaaagt agagatcagc tacctaacgt tgtatttgga gttagcattt cgatatcaaa
     4741 aagagcattt ttcctctaaa aaagtagcca ttgttcatac gacaggaaaa ggaacagcat
     4801 taatgatcca aagacaaatc aaaaggatat tggggaggga tatacaaata acacatgttt
     4861 cagaagaaca atatgaaaaa gtagatctaa acaaatattt cgctgttttt acaacgattc
     4921 cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt gactaatctt tttgatgact
     4981 cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg attagccggg tttcattcta
     5041 ctgttttttt ctatcaaata tggaaagaaa aaaagacgta tcaagaatat ttaaacaaat
     5101 tagtcgctcc tttgatcaga ggctattatg tggatgaaga atttgaaaaa aggatcttga
     5161 aaagagaata tcagcaaagc acatttgtta acaaagaatt tgcttttcct cacacaacca
     5221 accagctatc tcaacacatt gttttatcag tagggctaat aactgatcaa ggtttagcag
     5281 aaacaggagg aaatggagtt atttttttat ttgccatacc tgaagaaatg acggctgaag
     5341 ttgagaatga attatttgag ctatacgata tcctatttga actcataaaa atgggaatag
     5401 atgagtttat tgaattagca ccgacacaag aatcattttt aaaactaatc aaaagtaaag
     5461 gagagagact tcatgaatga tatgtatcta ttcatagttt tcgcagcttc agcttatgtg
     5521 ctgcaagcag ttatcagttg gaagcaacta aagcatttca atcaaacata tagcgaactg
     5581 cgaagaaaag gaaaagtagc gattggtaaa cgacctggga aaatccgttc aggcacgatt
     5641 gttatgctag ctatagacga tcatgatcaa gttttagaag tcagaaaaat gcaaggggtt
     5701 acatctttgg caaaatttca ttcattacct gtctatgcgg gtgaagatat ccattacatc
     5761 gatcgttacc atccctcagt tcgagcggaa gatcgtttga cacaagcagc tttagaaaat
     5821 gccagagaag tatacttacg aatagaggca ggaaatgaaa aaagtgaaca accttcattg
     5881 ccttttattg ctatgctcaa taattttcgg atatggaaaa gtacgatcaa agaaaaaagg
     5941 agtgacaaac gatggatatc ataacaaaat ttgctgaggg atttatgagg ctgttccaaa
     6001 caggtgcaga aacattcata agctggatga caggaatcgt accagttgtc ttgatgctga
     6061 tggttgcaat gaatacgctg attgcttttt taggtgaaga ccgagtaacg aaagtagcca
     6121 aattatcagc gaaaaatccg cttactcgtt accttgtgtt accgttctta tctgctttta
     6181 tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct tccagaatac tacaaaccaa
     6241 gctattatgc tgctcaagct caattttgtc atacgagcaa tggtgtattc ccccatatta
     6301 atcctggaga attgtttgta tggatgggga ttgctcaagg gatcgaaacc ttagggctaa
     6361 attcgatgga gctggctatc cgatacttgc ttgtgggact gctgatgaac tttattggtg
     6421 gttggataac tgattttact actggatttg tatgcagaca gcaaggaatc gttcttagca
     6481 aaaaagtaga gctttcagtt gattagagaa aggagagttt taaatgtatg gtgatattaa
     6541 gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt attaggccga caaaagataa
     6601 acacaagttc atctatgtca caggtggagg tgagaggcca atgatcgtag ataaaataga
     6661 agaactgaca ggtatggagt ctatcaatgg gttcaaaaca tcaatacctg atagtgaaat
     6721 cgcgcttgca atcgttgact gtggagggac tcttagatgt ggaatttatc ctaaaaaagg
     6781 gataccaacc atcaatatcg tttccacagg aaaaagtggc ccattagcac aatatatcac
     6841 tgaagatatt tatgtttcag cagtagggtt agaacaaata cagccactaa tggaaactga
     6901 tgataacaaa gaaacagtaa atactgcatc tccagataaa aagtacaaat atgatacttc
     6961 taaaaagata accgagcaaa aagcagagca gcaaaactgg atagcaaaaa ttggaatggg
     7021 cgcgggaaaa gtagttgcta cattcaatca atcagcaaga gaagcagtag atacgatgat
     7081 ccggacagtg atccctttta tggctttcgt ttcccttttg attggtgtga tacaaggttc
     7141 tgggatcggt aatgtatttg ctaacattat ggcaccttta gcaggaaatg cagttggatt
     7201 aacaatcatt ggctttattt gttcactgcc atttttatct cctttgcttg gtccaggggc
     7261 agttattagc caagtgattg gaacattgat cggtgtagag attgggaaag gaaatattcc
     7321 tccccaatta gcattaccgg cactatttgc tatcaatact caaaatgcat gtgattttat
     7381 tccagtcggt ctaggtttgg aagaagcaaa agctgagaca gtagaagtag gtgtaccatc
     7441 agttctttat tcaagatttc ttaacggcat cccacgagtt atcattgctt gggtagcaag
     7501 ttttggatta tatagctga
//
LOCUS       DAZKPE010000101         7483 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000101 DAZKPE010000000
VERSION     DAZKPE010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.102"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..638
                     /locus_tag="ACG930_002649"
     CDS             <1..638
                     /locus_tag="ACG930_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFQ0519765.1"
                     /translation="KITHQENRQKNLIVQNLNYGTNQYSVDSSKFELCDTSMKTRDKN
                     NFADSSKNELELYKSYKDSKDIKESHNDDLLESLSTKNNKLDEELIETFIEENLLKQI
                     WGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAEKEQKIQLKIIYEICNNKYFVDHV
                     REQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGIDKQ"
     gene            714..932
                     /locus_tag="ACG930_002650"
     CDS             714..932
                     /locus_tag="ACG930_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519766.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            919..3597
                     /locus_tag="ACG930_002651"
     CDS             919..3597
                     /locus_tag="ACG930_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFQ0519767.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            3588..3785
                     /locus_tag="ACG930_002652"
     CDS             3588..3785
                     /locus_tag="ACG930_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519768.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            3789..4400
                     /locus_tag="ACG930_002653"
     CDS             3789..4400
                     /locus_tag="ACG930_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFQ0519769.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            4385..5776
                     /locus_tag="ACG930_002654"
     CDS             4385..5776
                     /locus_tag="ACG930_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0519770.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            5992..6306
                     /locus_tag="ACG930_002655"
     CDS             5992..6306
                     /locus_tag="ACG930_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519771.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            6299..6793
                     /locus_tag="ACG930_002656"
     CDS             6299..6793
                     /locus_tag="ACG930_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519772.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            6861..7175
                     /locus_tag="ACG930_002657"
     CDS             6861..7175
                     /locus_tag="ACG930_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519773.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            7274..>7483
                     /locus_tag="ACG930_002658"
     CDS             7274..>7483
                     /locus_tag="ACG930_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFQ0519774.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         2881 a         1012 c         1439 g         2151 t
ORIGIN      
        1 ataagataac ccatcaagaa aatagacaaa aaaacttgat agttcaaaat ttgaactatg
       61 gaacaaatca atattctgtt gatagttcaa aatttgaact atgcgacaca tcaatgaaaa
      121 caagagacaa aaacaatttt gctgatagtt caaaaaatga actagaatta tataagtctt
      181 ataaagatag taaagatatt aaagaatcac ataatgatga tcttcttgaa tcactttcaa
      241 ctaaaaataa taaattagat gaagaattga tcgaaacatt tattgaagaa aatcttctta
      301 aacaaatatg gggagaaagt attgtgaatt gcttaaaact ggctagcaat agtgattatc
      361 gtcaattcga caactggtac aaaaaattca aatatgcgat tagatctgct gaaaaagaac
      421 aaaaaattca actgaaaatt atctatgaaa tttgtaataa caagtatttt gtagatcatg
      481 ttagagaaca gctatcaatg actttacgtg acttgatacg aagagcaaaa acagatcatc
      541 gtatcaaaca aaaagacgat tatatctttg cttctctaaa aaataaagcg ttagaactaa
      601 ttgaattgca aatcagcgaa ggaatagata agcaataaga atagaattga gtcaaatgaa
      661 atggaggggt atctccactt catttgagaa ctttgaatat aggaggggtt attttgatta
      721 aaaatcgttt aatagatcaa gtttggtgtc tagatcaaaa tacagatagt ctcgaattaa
      781 tcgagactat ttgcttcaac actatagttc tcgatttaag agctgaaaat gataattgtg
      841 taactcatgt cataattaat caaaaaatgg ctcagaagct ctctgagagc ctcagaaaat
      901 gggctaaggg aggtaacgat gaaaataatt gaaaaaaaga ttgccaataa aaaaataaat
      961 tggttggttg ttaattttct tgttctgata gctatgatta tttttacaag taatattgct
     1021 catgcgagta ttttcaattg gtttgatgac acaaaaagtc aaacagagtt tttgaataat
     1081 tctctttata gaccttacct aaaaaagtac aatggagatt tccttagtca gttcgggatt
     1141 tggctcggat gggctgtggt aaaaggcatg tttactgtga cagattcgat tcaaaatatg
     1201 attccagatg tgctggattt gttcaatttc attgaaagta cagggctaaa taatgtttat
     1261 caatcagccg taaatacaat tgtcattgga ttaatgatcc tttcattgat gtttgttggt
     1321 tacaaaatga ttactggaaa aggaacagtg gatttaaaat cggttggaat gaacgtagtg
     1381 atgtctatag cattaatact tttaatgcca accatgattt ctagtggtat tcaatttgct
     1441 aaaacatttt ataaggactc tactacgatt acaaattcag atgacggagt cgcttggtca
     1501 ttgataaaac aaggagtaac agatttagca tatattaata aaacagatca gtactcaagc
     1561 attgataaaa cggaggatcg aaataattta acacgaaaaa attttcaaca gacggatctc
     1621 acacaagtgt taacggataa agtgattgat aaattggaaa aagaaaatcc aattgcggac
     1681 aatcttcgtt atgaattagt tgaaaattct aataatgaat ttgttgctac aaagttttct
     1741 gacaacttct tatcaacatt ttctgatagc ttgaaatcag gctattaccg ataccaagca
     1801 aatctatggg ggatttcaat tgggttgaca gcgttagcaa tcgcctatgt gttcagcgcg
     1861 tttgtgatca ttacagcaat actagaactt gcatttaaac gtgtgttagg tgttcttgtt
     1921 tttgcaacag atattgagac aggacagcgt tcaaaagttg ttctatcaga tattctacaa
     1981 tgttacttaa ctgttgggtt tcaaggattt gggttatcaa tgtttgctat gtttatcaat
     2041 tttctgaact caggacaagg tatctcaaca aatattttta taaaaacaat tgcttatatc
     2101 tgtgccgttt ttgttttaat caaaggcagt ggaacagtca tgagatactt tggtgttgat
     2161 attggactca aagaaggcta tgggcaactt gcttctgctt ttggaatggg cgcaatgctg
     2221 tttagaaaag gatcaaatgg atttaatcgt gctaaaggaa gcggagaagg agaagatcga
     2281 aaaccagaaa agaatttcgg cgaaactcta tcaaaaaaag ctggcaaaac tggaagagct
     2341 ttgggatatg cccatgaacg tggattatcc ggtttagctt cagatggagc tacaatggct
     2401 agtgaaagag caacaaaacc atttaagagt atgcgtgata tagctaatga taccaagaat
     2461 aagtttaaag aaggtttaga tgatggtaca gtgtccgcta ttaataaaaa tagcaaacct
     2521 atgttagcta aaaataaaga agatgaaact ggaaaatatg ctgattccgt gccaacacgt
     2581 ctttcagata gaaaagatgg tgctaaagtt gaaaatgccg atagaattat gtctagttct
     2641 gaacgtatgc gtgaagcaat gaaaaataat gctgaatcga ataataatcc tgcaagcgca
     2701 attcagcaaa aagtccaaca agatattgaa gaacgtaaaa atgctatgca cggtcaagct
     2761 aagtctgctg aagaattaat taatcagaag cgtcatgaag cgaaatacac gcctgaagca
     2821 atgaatcgcg aggaaataat gttaaggaaa cgtgtagaag ggcggacagg cgctaatatt
     2881 gacggaaaag aagcgttgac caaagaaaga attcaagaag ctaaaaattc aaatacagga
     2941 ttagaaaaat tagtcaaaga aaatccacaa aattctacaa gtagtcatgg tggccgatca
     3001 gtagatgtcc gagaaaatat tcaaggttca ctgaatggtc atgttggacg gaatgttgat
     3061 gtaagagaga atttacaaag ttcttcaaat gctcaaggta ctaagacaat tgatgttcga
     3121 gaaaatctgc aaagtagcag tacaagtcaa ccaaaaacag tagatgttcg agaaaatgta
     3181 caaaattcta caagtagtca agggtttaaa tcagtggatg tccgagagaa tgtgcaaggt
     3241 agcagtgcaa gtcaaccaaa aacagtagat gtccgagaaa atgtacaaag ttctacaagt
     3301 agtcaaggat tcaaaacagt agatgttcgg gagaacattc aaaaagatag tggagaaatg
     3361 aaagaaaaaa cacaaaaaat caatatcgtt gaagacagaa agtcagcgaa aaaatttgat
     3421 tcaaatcatg aaacagtgat tattgatagt gaaatccgtg aaaatgataa gggatcaaaa
     3481 tcaagacgaa gattcactta tgaagacaat gagttattca gagatacact taatgatcct
     3541 aatccacttt tcgataattt attaagaaat aaaagggggg gattgtcatg caattaattc
     3601 taaagattag tacgcatgat ttcttagaac ttgacgaatt atgtgaatca gtaaagaacg
     3661 caacaaatga aaaaatcacg gtcactaatt atattgaact gatgattcaa gaagaattaa
     3721 agatgaaaaa tgaaatagag agcaatttca aatgttgctc tctagaaaaa aatgtgaggg
     3781 gataatcaat ggatgataaa caaaaaatgt acgaaaaaaa tcgcaaacat agtgaggcct
     3841 taaattttcg tgtcgataaa aagacttatc ttgaactgac attgattgca aaacaaaggg
     3901 gaatttctag agcagacgtt tgccgtgagc ggttaaaggg actcaaatat gaaccgccgt
     3961 tgttagctga agatgatagg gtagttttaa ccaaacagtt aaatcaaatt ggtaacaatt
     4021 tgaatcaagc ggtaaaggca ttaaatatca ttgctaaata ttttagagaa gaatctgaag
     4081 ataaaaaaga aaagagccta cattttagtt ttgatgctag ccgttacaac atttttaaag
     4141 atgaacttgc gaatagcata gcaaaaaagt tgatgattag ttatccagat gacatttttt
     4201 tggagtccaa tcggagtgcc ccctcttttt ttaaattatc agaagtagaa aaagaatatt
     4261 tcgaatattg gatagaaaag caaactagac cgggtacgaa agaagagtat tcccaaaaag
     4321 ttgatcggaa tttaattcac tcaattcaga ttattgcaag tttaaaagat gaggtgaaac
     4381 aactttggga gctactataa catcgaaagg acgcaagaaa aatttatcct cgctattaca
     4441 atatgcagct aatccttcaa aaaaagaaaa atgtgttgca gtctcaggaa taaattgtag
     4501 tgatgatagt gaggaagcac tgcaagaaat gaatttagta cgtaccaaga tgaataaatc
     4561 taaagatata gcacaagcgt ttcatgttat tcattcgttt gataagagta cttctaaaga
     4621 gttaagtatt gataaaatgc acgaaatagc tgtcgaattt gcagagaaag cttttccaaa
     4681 ttcgcaaatc attgttgcaa gtcacaatga taaagatcat tttcatagtc atcttgtcat
     4741 taataatatt aacatggaaa catgtaaaag gttgcgtatt gaccctaaag atttagaact
     4801 aatgcgaaaa attaacgatc aagtcctcaa tgaacatggt cttgaatcag tgaataatga
     4861 gtactatgaa aacttagaaa agagaaccaa tctttattca aacgatcctt ctaagatgaa
     4921 atatggaaaa attaattatc aagagtttgt gcaaaatgcg atcgaagcaa cgttggaaaa
     4981 atgcgaagtg aattcttttg aagatttttc ggatcatttg gcaaaagaat ataacattga
     5041 agtttatcaa ttttcaaaaa caaataacaa acttggctat gttctttaca aacaaggtgt
     5101 aaatttctat gagcgtagag gtgagttaat tactttagga agagataaac aatctagaaa
     5161 agaaaaaagt cagtatgtcg aacgtacttt tagtgcaaga aagttaggga aaagatattc
     5221 atttgaatct gtttctgaac aacttgaaaa gaatttagaa gaatcacata taaaaaattt
     5281 ttttaatatg gaaagagagc aagttatgtc gctaattagt ggagtaaatt acaaaactgg
     5341 tgagttaaat gtaccgtttg tggaattaga ttccatcgca caaaagcaat ttagcgaccg
     5401 tgaaggcgat gaaaaattca ttaaatatga tgacttcttg cgagaggtag acaagcattt
     5461 tgtaaataca atgtctttag aagatgatca agaatacacg attaaacttc atacggatgt
     5521 gaatcctcaa actttacgta gtgcgaaaag taaaacaatt tctattaaaa agactgatca
     5581 gaaagagtta tttctaccgg caaagggttt tgaaaattgt tctcatacac cttctgctaa
     5641 acagattcac tatcaaatca gtcgcataat gaatgacgat gtaaaaatgt atcgtgctaa
     5701 aaaggattat gaattcacac aacaaatgat tgaaaatcag caaaaaaggc aacaaaattt
     5761 tgaaatggaa ttctgaatgg gcttgttagt ggactttcca gttttttgcc tatgaagagt
     5821 tgcttggaaa gaagcagttt ttaggacata cgccagctac ccatctactt gccagtcaat
     5881 ccgccccgct cacgctaggc tactttctgg caagtcagat ggcgggtaaa tctctgaggg
     5941 agcaagctcc ctacagactc cctcccaaaa aaagaaaggt ggaagaaaaa aatgaactat
     6001 ccatatttta aagtctcggc ttcagaagaa actaaagaaa tattcaacaa tttttacaac
     6061 caaaacaaag gaatttttgg ttcaaaggca aatatgtttc gtgttatggt ttcaaattta
     6121 ccagtgttag ctagtccatc aaataataaa tttaatgatc ctgaaagcat taaatttgaa
     6181 caaaaaattt cagaactaga atcaatgata agtaatgaag taattgaaaa gctggatgac
     6241 attgatcaaa agttatcgta ttctctaaaa aacaaataca aaacggagga gaaaaaagat
     6301 gtttaaagtt tacttcccgt ttcagtggct cgttaaagga attcttttag tgctactagg
     6361 attgattctt tttggaagtt atctaacaat taaagccaga cattttccag aagaaaagcc
     6421 aataaaaatt gtaacaaaag atttaaaaat aggtgaaact tatcaggcag atggggttga
     6481 actaacattt aaaaatattg aagtgaccga aaaaagaaat gaatttgcac aacatgatcg
     6541 tgtattacaa gtgacctata cacttataaa tgatacagaa aatccgatac gtccacaaca
     6601 atggtcgatt gaaaataagg atggtgaaga actttatgag tatgatatga tattggataa
     6661 tccagagtat attgaaagtg gcaaagaaga aacagtaaat tactattatg aattaccgat
     6721 tgaaaggcag gactaccaaa tcgtagtacg tagagagaat ggttacatag ttgggttgcc
     6781 atttacttta taagttttat tttgttagta gtttttaagg taatatcagt tttgtgattt
     6841 ttgaaaatgg aactgggaga atggctgagg aaaataaagt tgttccgttt gaaacattag
     6901 tgataaataa ggaagagttt gagcaacttt ttcttgattt ttttattcaa tatgacatga
     6961 tttatgattt tagttcgtca ctagatttat ttgaattaga agcagaaata atagaaaaca
     7021 gtcgagagaa gaatggtaaa atcattattt cagtagaaaa attcaatgaa ttattctcac
     7081 aaacatttga aatagatcca gactattatc aaccacaaga agtttttcga gagtttagaa
     7141 ataagattat tggttttagt caaactacaa aatgaaagct taataaagca agtgttgata
     7201 gaattattcc tcaacgcttg ctttatttta tgggcacttc ataatagagg tatagagaag
     7261 agaggtattc attttggata ctattactcc aacaaacttc aaagaaaata taggtaaagt
     7321 gttgcaagaa gtagttcatt caaattctga aatagaaatt actagggatt ctaaaaatgg
     7381 attgaacgat ggcgtcatta tgatttctaa gagaaaatgg gagttgttac aagaagaact
     7441 ttatttacaa cgaacgggta catgggctta tgtatctgat tta
//
LOCUS       DAZKPE010000102         7093 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000102 DAZKPE010000000
VERSION     DAZKPE010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.104"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..989
                     /locus_tag="ACG930_002659"
     CDS             <1..989
                     /locus_tag="ACG930_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HFQ0519775.1"
                     /translation="SNIHGEHFIKTVLVTERMSVNAFIDYCPDLVITIGKHVWSFVKY
                     TLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGVNSNNNLEYYNLW
                     KTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDFVSDDKALLSFAN
                     LGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIPDNAHIFLINNHS
                     GSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADSKESLKSGLDVFI
                     NTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIKKHLHIK"
     gene            1015..1851
                     /locus_tag="ACG930_002660"
     CDS             1015..1851
                     /locus_tag="ACG930_002660"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFQ0519776.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            1856..3289
                     /locus_tag="ACG930_002661"
     CDS             1856..3289
                     /locus_tag="ACG930_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0519777.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            3327..4967
                     /locus_tag="ACG930_002662"
     CDS             3327..4967
                     /locus_tag="ACG930_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFQ0519778.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            5055..5453
                     /locus_tag="ACG930_002663"
     CDS             5055..5453
                     /locus_tag="ACG930_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFQ0519779.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            5478..6194
                     /locus_tag="ACG930_002664"
     CDS             5478..6194
                     /locus_tag="ACG930_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFQ0519780.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            6361..7053
                     /locus_tag="ACG930_002665"
     CDS             6361..7053
                     /locus_tag="ACG930_002665"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0519781.1"
                     /translation="MSTVAVPTFFIISSFLLCSGEVTSAKLSKQIYRVLKIYIIWSIL
                     YIPLVLKNWVQSDFSWKTDVLLYIRDFLFIGSYYHLWFLPALAFALWLVRKSQVSKIK
                     FLSGLLLCVVGLAFESYWFILSGNDSIEYIRYCYKSVFVTTRNGLFIGVPCVIIGQHL
                     AFHKNTILNKVFKYRNFILCAVLAIGCLLVGESFIINQIALREVNNLLIFSIPLALVV
                     VSVSLSLKIVHL"
BASE COUNT         2282 a          936 c         1399 g         2476 t
ORIGIN      
        1 attctaatat acacggtgaa cactttatta agactgttct agtaacagaa agaatgagtg
       61 taaatgcatt tattgattat tgcccagatt tggtaataac tattggtaaa catgtatggt
      121 cttttgtgaa atatactctt agagataaaa agcttaaatt tgagcattgg cggatatctg
      181 aggatggtaa gattgttgat ccgttcaaca agctaacatc tgtctttcag tgctcagcgg
      241 aattttttat ggagactgtc actgctggtg tgaatagcaa taataatctt gagtattata
      301 atctatggaa gacaagatta tcaaaagttt gctatccaga gttagtctat agcaattttt
      361 atgcaatttc agaactagta aaaaaaattc cagatagtgc attagttcat tctagtattt
      421 taaatgcggc tagattgtat gactttgtat ctgatgataa agcattactc agttttgcta
      481 atttaggggc tgatggtatt gatggttgtt taccaacatt tttaggtcag gcagaagcag
      541 ataaaactcg acctgcgtat ttaatttcag gagacttgag tttcttttat gctatgaata
      601 gtttatgtgg tgacattcca gataatgcac atattttcct tattaacaat cattctggaa
      661 gtgaattcca tacaaatttt ggtaagtttt acaacggatc attaagtgtt gataagcata
      721 tagctgcagg acatatttca aacgcaaagg attgggcatt agaaaataat ataaaataca
      781 ttactgcgga ttctaaggaa agtctcaaat cggggttgga tgtatttatt aatacatttg
      841 acagtcctgt tttatttgag gtctttacag atccggatac ggatacgtct gttctggaat
      901 ctttttatag tataaataag gtaatcacac caaaaatgta ttttagaaag gcgttagata
      961 ttataaaaaa gcatttacac attaagtaga tgtttattgc gaggtgaaac aaatatggca
     1021 ataaaatctt atattaaacg gttattgctt tatatccgtc atggagatcc caaaataaat
     1081 ttagatgtga gttatttatc tgaaggtgca atgcttgctg gtaagactgt gataattacg
     1141 ggtggtgcaa aaggacttgg ttttgcaatt gcaaaatcat ttatagctca aggcgcaagc
     1201 gttattatta caggaagaga catggattcg ttgaataatg ctaaatgtca gcttggagat
     1261 atgtgttcta tcagggcgtt tgatataact gatgctaaaa tgtatcgaac gttttttgaa
     1321 gatgcatacg agacctttgg acgtattgat atactgctta ataatgctgg gatctcgtta
     1381 cacgaagatg gatttatgag tgttactgag aaaacttggg ataagcaaat ggatacaaat
     1441 ttgaaaggtg tttatttctt tacacaggaa tttattaagt ttgttaaaga aaagaatcaa
     1501 atgcaagcaa atattattat gatgtcctca gaaagaggct tgtgtggtga tagtattccg
     1561 tatggattat caaaggctgc aattaactct ttagttgtag gcttgtctaa gaaatatatt
     1621 tctgagggaa ttagggttaa tggtattgct cctggagtaa ctgcaaccgc tatgactggt
     1681 atttctgaaa agggtaattt gtataatcct gcaacgatcg gttatagata ttttctccca
     1741 gaagaagttg ctcaagttgc tttgtttttg gcaagtagtc tttcaaactg tatcagtggt
     1801 gaaatcatag cctgtgacca ggggcaatat ttaagtcgaa attgggggta ataacttggg
     1861 aatattatta aaaaaatata atagccttag tgagcctgca aaagcatcta tttggtttac
     1921 actttgtaat gtgttgcaaa aaggaattct atttttgact acacctattt ttacaagaat
     1981 gctttcaact gcagaatatg gtaagtatac gatttttata tcgtggtatt ctattatagc
     2041 aattttcaca acgttgaatt tatctgcagg tgtctataat aaaggactaa ttaaatacga
     2101 gaataaatat gcattaacct cgtcattttt aggattatcg tcatttattt ccctttgtgc
     2161 attgatgcta taccttccat ttagaacggt tataaatggg ctactggatt tatcgacgga
     2221 gtttgtcata ttgattctta ttgaatcaat atttgagccg gcttttttgc tttggtcagt
     2281 taaggaacga tttgattaca agtatcaaaa actagtactc atcacagttc ttatggctgt
     2341 tttaaatcca ggtctcggta ttatattaat cttatcattt ggggagtatg ctatttggag
     2401 agtacgagct tatgtcgtgg taaatgttgt agtggggatg tttattggca taggaatact
     2461 ggctaagggt aagaaattat ttgataaaga gtactggaca tatgcgctca gatttaattt
     2521 gccattaata ccacattatt tatcaatgac attgctgaat caggttgatc gccttatgat
     2581 aaatagtatg gttggagcta gcgaggctgc gatttatagt atcgcttaca ctatatctag
     2641 tatgatgaat atcataacaa cagctataaa cggttctttt attcctttta catacaaagc
     2701 aattaaagat ggcgtgtatg aaaaaattaa atccgttgct aatcaactat tagtgttgat
     2761 ttttgtcttg tgttcgttta ctatgctgtt cgggccagaa ttgatttggg ttgtcggagg
     2821 agaaaaatat atggatgctg tttggattat tcctccagtt gcggcatcag tatttttcat
     2881 gtttttatat ccgctttttg gcaatattga attttactat gaaaagacaa actacgtaat
     2941 gtttgcatct tgtgtgggct ctatcgcaaa aattatttca aactatgtta gtattccccg
     3001 ttttggatat atttcggctg gttacacgac attgatttgc tatatgttgt tttcctttgc
     3061 ccactacatg ttttataaaa aaattcttag agaaaatggt ataaaagaag atatgtataa
     3121 tattaaaaat attatatttc tttctgtctt aatgattgtg ttaactattg gtatgacaat
     3181 attatacttt tctacaattc taagatatag tattattatt ggattagtta ttgtggcttt
     3241 tcttaaaagg acgcaaataa tgaaaatcct taaaaatata aaaaattaac aagcaaatct
     3301 tgggaatgga acggaggcac ggtgaaatga gattattgat tccatctgct aagattgtac
     3361 cggaagaact tcaccatctt ggaaaacttc ctgcaattat ctatccgatt aatcaaaaaa
     3421 ttgtatttga ttatttatat gatcaatata aagatgtatg ttctgctatc gatattgcct
     3481 gttacgaaaa gatggataag gtagcaagac gattagataa gtatattaaa tctaaaacag
     3541 taaatattat tcagcttaaa gagttagggg atcttggaag aactatatat gattctctaa
     3601 taggatgtga cgagcctgtt attattaatt ttgctgatac cattatcaat gataatatat
     3661 attccttgga atgtgacagc tttttctatg ctgaagacta ttatagtaat acttggacat
     3721 tctttgaaga aaaagacgga gatattattt ctgttttaga taagaacgag ttaaaagaag
     3781 atgatggaaa gaagcacaaa ctgttttctg gtgtatttca aattatggat gcccagtatt
     3841 ttagagagtg tttgcgtaaa gctttgatgt caaatgtagt aaatgtgaat agtttttatc
     3901 aagctttaca agagtatagc aaacgatatg aatttctctc tattaaaaca aataattggt
     3961 ttgacattgg acatgcagat aaatattata attccaaatt ggaagttaag gcaagagaat
     4021 ttaaccacat ttcaattgat aaagatcgta gcatcctgag aaaaattagt gaagatgttg
     4081 aaaaatttat cggagaaatt aagtggtatc ttaagttgcc agcacaggta gaatatgtga
     4141 gacctagaat attcgaatat tctacttcgt atattaatcc atatgtaagt atggaatact
     4201 attcgtatca tactgttcac gagttatttc tctatagtga cttaacaaaa aaacaatgga
     4261 tagatatctt taatagaata cgatttgtat gctcagactt taagagatac tctgtttcag
     4321 gggataatat tcaaaagtca ttgaaagata tgtatctcga taaaacattt cagagattca
     4381 ataagctcag aaaggacccc cggttcacag aattcttttc ttctgatatt caaataaatg
     4441 gagtcagata taaatctttg gaccagatag aagctttatt gagcgtaagt gttccaagag
     4501 aattgtttga cattacgcaa tttaatatta ttcatggtga cttatgcttt gccaatatta
     4561 tggtagataa cacattttcg ttcattaaag tcatagatcc gcgaggtaag tttggagatt
     4621 ttgatattta tggtgattat agatatgaac tggcaaaatt gtttcatagt gttgatggaa
     4681 aatatgactt tataattaag gacttgttta caataaaata tgatccaaag aaggcaatca
     4741 tagactatat tgttcaagat cgtaaacgag attatgattt atatgaagta ttttactctg
     4801 tcttcaaaga tgaaataggt tctgatttga aaaaaattga acttattgag gctttgctgt
     4861 ttttaagtat gattcctttg catggagaaa gcttaaacca tcagatggct atgttagcaa
     4921 ctggtttgga aattttagga cgagttgtcc cggatattta ttgttaatgc tttgagctat
     4981 tgtttttcta tttgatcagt gtaaagccgg gcatataaat tgcctggcta aaataaagga
     5041 gatgtcttag ttatatgttt aaagattacg catttgtttt tgatattgat ggaactttgt
     5101 gccccatcaa aaagaaagat gagaaatatg aagatttagt tccgtatgct aatatggtgg
     5161 agaagttgcg atactataag gagaacggag caaagattac actgttcaca tctcgcaata
     5221 tgaattctta tcatggtaat ttaggtgtga tcaatgcaaa tactgcaaaa atcttgttgg
     5281 cttggctaga taagtgggag attccgtatg atgaaattct ttatggaaag ccttggccag
     5341 gccataaagg gttttatgtt gatgatcgca cagttcgtcc ggatgaattt ttatcgtgta
     5401 ccctggatca gctcgatgag atttgcaaaa aatccaaatt gaaatctgag taaaggagac
     5461 tttataaagt gaataagatg acggttatta ttacaatggc tggtcttggc agtcgctttc
     5521 gtaaagttgg ctacactgtg cccaaattta tgattgaagc aaaaggtaaa accttatttg
     5581 attggtcctt agacagcttg cttgattata attcacatgt agaaaagtat gtttttgttg
     5641 tgcgtaagga agatgatgct actgttttta tcaaagaaca ttgcagtctg tatggaattg
     5701 aaaatgtcga ggtagttgaa attgactata tgactgatgg acaagccact acatgtatgc
     5761 ttgcaattcc ttattgcgca cctgataatg caattatggt ttataacata gatacatatg
     5821 ttgagccagg tgagatgaaa tacgttgata tttctggaga aggacatatt ccgtgtttcc
     5881 atgcggacgg tgatcattgg agttttgcca agttgaacga atatggtgat gtagtagaag
     5941 taagagaaaa agttagaatt tctaacaatt gtactttagg tgcatattat ttttcttctg
     6001 caaaattata tgcatcactc tacgaagaat attatgcaga tgaaaggcat ctggaaaaga
     6061 atgagaaata tattgcgccg ctatataatt atatgataga gaagggcatg aaggtaacca
     6121 ttagtatagt agataaatca aaagttcacg tactcggtac tccagaagag ctcgatgtgt
     6181 tcttaaatga atagggaaaa tataatcata gaaaatgtta attataaagc tgcgtgtgtg
     6241 ggggagtact attcgataga tattctaaaa atactaatgg ctattttagt tgttgttcgt
     6301 catttaggtc aaaactattt agctccagat taagcattta gtattggtat tgttgcagga
     6361 ctgagtacgg ttgccgttcc tacttttttc atcatcagtt cctttttgtt gtgtagtggt
     6421 gaagttacat ccgctaaatt atctaaacaa atctacagag tacttaaaat ttacattatt
     6481 tggtctatat tatatattcc attagtatta aagaattggg tacagtcaga ttttagctgg
     6541 aaaacagatg tattattgta tatcagagat tttctgttta ttggtagtta ctatcacctg
     6601 tggttcttgc ctgcactggc ttttgctcta tggttagtac gcaaaagcca ggtttctaaa
     6661 ataaagtttc tcagtggttt gttgctatgc gtagtaggtt tagcatttga atcttattgg
     6721 tttatattat ctgggaatga ttccatcgag tatattagat attgttataa aagcgtgttt
     6781 gtaacaactc gtaatggatt atttataggt gtaccatgcg tcattattgg gcaacactta
     6841 gccttccaca aaaacactat acttaataag gtctttaaat accgtaattt tatcttatgt
     6901 gctgttttag ctataggatg cttattagtt ggtgaaagtt tcatcataaa tcaaatagct
     6961 ttgcgagaag tcaataattt gttaatattt tccattccat tagcactggt agttgtatca
     7021 gtatcactga gcctaaagat agtacattta taaaaataac agtacatctg cgaagaatta
     7081 gtacgttatt att
//
LOCUS       DAZKPE010000103         7091 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000103 DAZKPE010000000
VERSION     DAZKPE010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.105"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..863
                     /locus_tag="ACG930_002666"
     CDS             6..863
                     /locus_tag="ACG930_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0519782.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            885..1394
                     /locus_tag="ACG930_002667"
     CDS             885..1394
                     /locus_tag="ACG930_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFQ0519783.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1431..1832
                     /locus_tag="ACG930_002668"
     CDS             1431..1832
                     /locus_tag="ACG930_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519784.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1944..2297
                     /locus_tag="ACG930_002669"
     CDS             1944..2297
                     /locus_tag="ACG930_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519785.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2331..2774
                     /locus_tag="ACG930_002670"
     CDS             2331..2774
                     /locus_tag="ACG930_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519786.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2791..3876
                     /gene="uxuA"
                     /locus_tag="ACG930_002671"
     CDS             2791..3876
                     /gene="uxuA"
                     /locus_tag="ACG930_002671"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFQ0519787.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3869..4582
                     /locus_tag="ACG930_002672"
     CDS             3869..4582
                     /locus_tag="ACG930_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFQ0519788.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(4789..4938)
                     /locus_tag="ACG930_002673"
     CDS             complement(4789..4938)
                     /locus_tag="ACG930_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519789.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            5334..5534
                     /locus_tag="ACG930_002674"
     CDS             5334..5534
                     /locus_tag="ACG930_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFQ0519790.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            complement(5638..6939)
                     /locus_tag="ACG930_002675"
     CDS             complement(5638..6939)
                     /locus_tag="ACG930_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0519791.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         2376 a         1128 c         1520 g         2067 t
ORIGIN      
        1 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
       61 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
      121 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
      181 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
      241 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
      301 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
      361 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
      421 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
      481 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
      541 tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag acagcgattg
      601 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
      661 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
      721 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
      781 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
      841 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
      901 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
      961 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
     1021 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
     1081 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
     1141 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
     1201 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
     1261 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
     1321 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
     1381 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
     1441 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
     1501 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
     1561 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
     1621 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
     1681 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
     1741 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
     1801 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
     1861 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
     1921 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
     1981 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
     2041 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
     2101 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
     2161 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
     2221 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
     2281 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
     2341 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
     2401 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
     2461 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
     2521 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
     2581 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
     2641 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
     2701 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
     2761 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
     2821 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
     2881 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
     2941 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
     3001 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
     3061 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
     3121 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
     3181 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
     3241 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
     3301 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
     3361 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
     3421 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
     3481 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
     3541 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
     3601 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
     3661 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
     3721 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
     3781 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
     3841 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
     3901 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
     3961 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
     4021 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
     4081 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
     4141 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
     4201 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
     4261 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
     4321 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
     4381 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
     4441 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
     4501 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
     4561 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
     4621 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
     4681 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
     4741 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt
     4801 ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc
     4861 tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc
     4921 tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa
     4981 cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta
     5041 agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa
     5101 tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta
     5161 tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct
     5221 attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa
     5281 tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata
     5341 acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg
     5401 gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag
     5461 aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca
     5521 ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gggctctttg
     5581 tcaaatagga ctgatagagt gagataagaa catctaaggt agaattcctt ttctacttta
     5641 gatgtttttt gattcatagg taatcagatt atttagtaag aaaattctgg tcttcatttt
     5701 ccgaaagctt cgaaagccat aagcgactcg tttcaatgct ttgatgtggg tatgcagatt
     5761 ttctattttg gcatttgaat aaggcaattc gagggctaaa cgaatgccgg attcatagtt
     5821 tataaaagct ttttttatag aatgcagttc ttttggaacg gaattgggca tcgttcttac
     5881 aagtttaaag aaagtgtccg cctctttgtc gtgaaacgct tgaagaattt cttgatagta
     5941 aaaataggcg attcgtaatt cgtcagagat cgaaagcaga cgatccacca cttcactttc
     6001 ggtgagatac gcccaaccaa aattgcgcca tttggtccat ttgtcataaa caagcttgtc
     6061 ctgtcgtttg atcagaagcc gagacaacgc ctttaattgt cgataatatt tggcttgtgt
     6121 tggatcgttt cgatcaaagc ttttcatgat tcgtacgcga atatcctcaa atttacgaat
     6181 gagatgtttg acaatgtgaa aacgatccac aacgagtttt gcctttggaa aacattcctt
     6241 tatcagagag gcataagaaa cattcatgtc cgtcacgatg acctttacct tcaatcgtgc
     6301 gcgtcgttca aattgcataa aataagaaac gagagccttt ttcttccgtg aaggaagaat
     6361 atccagtaat tttccagtat cgccatccat acaagaaaag gagtagggac cgacttgatt
     6421 tttcagtgaa cgaaattcat ccattaataa acaacgcggt aaccaatttc tttttacttt
     6481 tgtcatgggg atcagagaag cgagtgtccg agaaacggtc gaccaagaaa cgccgcaatg
     6541 cttagcaatt gtcgtcattg cttgtttttc agttagctct tctaaaattt tatagcgcac
     6601 ttgtttagcg ataaagcagt ttctatcgac aatgtaggta ttcgccgtaa aataggtgtg
     6661 gcagccacga cagtggtagc gttgtttcgc taaagcaaga taagtcagtt ggttcgcaca
     6721 tttattaagt tgaatgagcg attttttctt tccgttctta acgatcatgc cttcatgatt
     6781 catctgttta cacaaaggac agcgacgaat ttctttactt aacgtcgcag aaacaacaag
     6841 actcttgata ttcttaatgc tcttcgattc cacatttgtg atgaaaatgt ttttatcttt
     6901 gattccaagt agtagtttga tatgatgaag atcaggcata cagaacgctc ctttgattgt
     6961 gttgtggtga ttcaattcta acggagcttc tgtatgtttt gttttttcat gctcaaaagg
     7021 gaccgataga atgattttct atcagtccta gaaattatag agccaagaaa agacggtttt
     7081 tttgtacgaa a
//
LOCUS       DAZKPE010000104         7042 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000104 DAZKPE010000000
VERSION     DAZKPE010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.106"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(159..494)
                     /locus_tag="ACG930_002676"
     CDS             complement(159..494)
                     /locus_tag="ACG930_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519792.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(528..722)
                     /locus_tag="ACG930_002677"
     CDS             complement(528..722)
                     /locus_tag="ACG930_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519793.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFKTIS"
     gene            complement(889..2859)
                     /locus_tag="ACG930_002678"
     CDS             complement(889..2859)
                     /locus_tag="ACG930_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519794.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2874..3740)
                     /locus_tag="ACG930_002679"
     CDS             complement(2874..3740)
                     /locus_tag="ACG930_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519795.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3730..3963)
                     /locus_tag="ACG930_002680"
     CDS             complement(3730..3963)
                     /locus_tag="ACG930_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0519796.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3975..6131)
                     /locus_tag="ACG930_002681"
     CDS             complement(3975..6131)
                     /locus_tag="ACG930_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519797.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(6151..6396)
                     /locus_tag="ACG930_002682"
     CDS             complement(6151..6396)
                     /locus_tag="ACG930_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519798.1"
                     /translation="MREESKCKMVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQF
                     YDYRNGSKKIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            complement(6482..6820)
                     /locus_tag="ACG930_002683"
     CDS             complement(6482..6820)
                     /locus_tag="ACG930_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519799.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
BASE COUNT         2012 a         1358 c          954 g         2718 t
ORIGIN      
        1 gtcgcttgat ttatatattt ccctcttctt tctttagaat ctctctttat tttgatataa
       61 taaaatagaa atcgcaccaa acaatgaaat ggcggaaaac atttcattga aaaaaggatt
      121 gaacataatg ttcaatcctt ttttatagtt ataatcaatt aacattcggt gtgtgaaatt
      181 gaatcttcga tgctttcaca tggaaaatta ttgattcctt cttcactcat ttcccatgta
      241 gtatagaaag gagttaactg tcctccatac tcctgaataa taaaatattt tccatcattg
      301 atatggttac aacagtacac tccaatagtt ggatactcga ctactaaaaa ttggtctgga
      361 tcaaactgtt cttttttcaa catttctcgt atttgaaaca aatgatcctt ctctaagcaa
      421 tcaggtaatt cctttattct ttgcgttact aatgacccct ctatcgcttt ccattcattt
      481 aaatattgtt tcataacaat tcattccttt tatgttaact atttttccta ggaaattgtt
      541 ttaaaaaaaa ctctcgcttt ttcttcatca gtaaagtttt tatacaactg attacaataa
      601 tgaggttttt gaagtttctg aatacctata ctaacttcaa atccttcttc atgttgaatt
      661 aggattactt ctgtgtctct acctagaaat attcgatcta aaatttttat gtttggtttc
      721 attatttaac ctccactata attatttcac tcagtaaggt ttcactttat gaaatttcta
      781 tagttctctt ttcacaaaac gtaccatgtt ctctaagact gtttttagtc tcaaatatac
      841 atgttttttc ttatcctttc cttatacact caaaatcaaa gataaaactt aaagaataaa
      901 ctctccaata acaaaattat tagtcagatc cactggtctc ctgatctgaa atttattact
      961 tcttcctgtt gtcaaatact gtctcaaatc aacagaaagt ttttgatcat cttctccttt
     1021 tctagcagga gcaacttttt tttcatactt cattaactct ccactggtca tctttccaat
     1081 gatagtgtaa ttaaaatcac tttcaaaact ttggtaaatt tttccatctg tattgaatat
     1141 atcagctgtt tcaatatctt ctttgtattc attgtcttct cctgaaccga ttgtatcaaa
     1201 tagaaaggca agacgaattc catcttcttc aagcattgtt aatctttttt taattagccc
     1261 aacggtttca atagataact tatcgaagcc gtgaatcata acaatatcat ctttttttgc
     1321 ttgtgatgtg atgaaatcaa aggtatttaa aaattgagct tccataacat tggtttctgc
     1381 tcttagatca cctaagttat agtaaaactg taatttgtca cttttaccga tttctttcag
     1441 tgtcgttctt tgattaaaca tcctagagaa gctgtctaat gctgttctca atgtgtcttt
     1501 taatacaata atacgatcga cttctttttc agtaccagat tttttggctt ttgtttcagc
     1561 attagtcaaa tagctaataa aatccccaag aactggcatt gtatcactac tgttcaccaa
     1621 aagttttgaa cgttcttcat aattaatatc ccaaagtttc tgacttatat aaaagttacc
     1681 taattctttt ttcaataaaa ctctagttgc agaatctaat gttctgcctg ctaacaaata
     1741 aaaaatctga gttagtttat cgagattccg tctatataaa tcaccaatgt ccttttgatt
     1801 accaaaaagc tccaaagagt taagaccttc ttcagccaaa ttaacctttt ctattacact
     1861 gtttaacgaa ggtttggcaa caaatgttct accagttgga tcaccaaagt aatcaaattt
     1921 atttaagaca atatgaaaag ttcgtttatg atttgccatt gcattattag caatcaattg
     1981 cccccaaagt gatgatgctg agattttttc atcatagcct ttaattgtag cgtttttgtg
     2041 tgatgccact aaaactttac ttgtaaaaga atcatccagt gccataaaag ctacaccact
     2101 tgcgtagcta gtagacatag tgccgatagc ccatccattc gcatcatcta aacctttgcg
     2161 aattgcatga tcatttcctg caaaatccga actcatagac gtatactcat agacattccc
     2221 gattggttca cttaaaagtc tatcaaacag atcacgttga tctcctccat atgacataag
     2281 ctttaatcca tacatttttt catcatacaa ccgttggagt ttaattagct gttcgctgat
     2341 tttattagga gaatcggata ctaataggat ttctagcttc caatcaataa ttttatttgc
     2401 catgctgtct agtaaagatg ctgtattcaa atccataatc cgcataacag ttttgctaat
     2461 ttcagcatct gaattttttc cttctaaatt attttcataa ctattcgttg atcccccaac
     2521 attctcgtgc attatttctt gttgatcttt ttgtgacact ggcttatctg cttcaattag
     2581 ataggctttt accccttcta ctctcacttc aggaatagct ttaaccatcc aaccaaatcc
     2641 ataatttcta ttcattccat aagtattcac taatttcaca attgttcccc accgcttacc
     2701 tgtcctaatg taagatggtg taaattgata accaactaaa gatgttaaat cactaacaaa
     2761 ggtattattc actacctttg aatttctagt tttttgttct tttttagttt ttctcttttt
     2821 tttgaaattt aatagttgtg atctacccat aatttccatt taatctctca cctctatttc
     2881 agtgcataaa tatcagataa tatttctttt gtttgtttag ctgacaactg agtgacacta
     2941 taataaagtc ctctactcgt atagttttct aaacgttcca caccttcatc caataccatc
     3001 ttagattgag atttcaagat aagatattgg attactgttg ttttcacacc atcaatatat
     3061 tctgatacaa atcgttcttg ctgatctatt atgtcaaaga ctgctttgtt actccttgca
     3121 tttcgttttt gtattttcat atttcgagtt tgtctttccg tattctgagg ttgagatgaa
     3181 gtgattttga tttcagctaa ggaacgatct ctggtatttt gatattgtat tgatttcgat
     3241 tcctgagcca taacttcttc tggaaaagcg gttagtgatg tagccccatc tagattgaac
     3301 attaatgcta cactcccatc tcgatatacg attgttccat cttgtttcac ttttaaaatc
     3361 tctgtgcctc gaaatggttt ctttttcccc atagatactc ttgctgaatt aactactgat
     3421 ttgaacagtc taatagaacc agaaatcaat gaaccactag atggatcaat aaacatatac
     3481 tggctaatta gaataagaaa tccaattatc attaataacg ttggaacaaa aataaatttc
     3541 agtttaatcg tatcagaaac taagtaaaca attgatccaa gaacaacgac tgcaacaact
     3601 atagctgata caattaatct ttttgctgta acagaatagg tgctattgac atgcttttca
     3661 agccattcaa ctctgacaat tgtttcagaa ggtttttgat gtaagttatg tttaaatcca
     3721 tagtttgagt tatctgccat cagaaatact tcctttcacg ttcaacttac ggtaaacacc
     3781 tacagttatc actattgcaa caataagcaa gccaattaaa gatattgact tgctcattgt
     3841 ctcgttcgtt tgtggtagtt catttacctg atacacgagc tgtgcttcct gtaagtgctg
     3901 agaagaggtc atgttttctt gattgttttg aattactgga taaactattt tttcttctcg
     3961 cataatagcc ctccttagtt attatcagat aagtgagctt gaattttgta ctgatttccg
     4021 tctggagttt tcacaactgc tttttctcca tcaatagaaa tcacttcagc cttagttgtt
     4081 ttcccatcaa tactgatgac aacatctttc ccaactttga actctgtagt tggtgttgct
     4141 tcatagctac tatttgttga agcagagttc gtatttgtcc caatcgaatt ttccactctc
     4201 gaaatagatg tttgagtttg agcctgtgct tgttgattat tatgactaat aaagtaggac
     4261 gatcccaaga tcgttccgca agccattgca gcgacagaaa tgatagtagc catcttttta
     4321 cttgtaaaat cacgttttga acttgattga ttttctgtag caactgctaa tgatttcgtt
     4381 ttttctgcca tttgagctag atcacttcgg gaacgagata agtcttctct taaagcttca
     4441 ctttgttctg ccaacttttc gctatttaat ttataaccct ctgctaaatc tttgacctct
     4501 ttcattcgat ctttatattc ttcgatagtt ttttgttgct ctacaagttt tgtttctaat
     4561 tctttcgtgt tgttagctac ctgcttttca acttcttctt tgttcgcaaa atatttgaca
     4621 accacatctg ttgttttctc ttttgtatca tggaactcag cttcattttc tgactttgtt
     4681 ttttcgacaa tctctaaagt tttttcttgc acgtctgtta atgatttttc aatttctggt
     4741 ttcaatgaat tgataattcg ttccaccaca acttcttttg cttcttggct ttgtttcaat
     4801 gcatcgtttt taatagattc aattgcttct tggtactgtt gatcaagact ttcttcagtt
     4861 gcttttctat attcatcttc ttgttgttta acttctggta aatgctcagc atcataccgt
     4921 tgctctagtt tctttagttc agcatccaaa taagcctgtt tcgccatatc ataatcttta
     4981 cgaatgatat tggatttttc catcactaaa tcatcaattt tagatgcttc tgcttcgtag
     5041 ctctctttag caaccgatag tgtatttgta aactgatttt gaccatttaa tgaggttgct
     5101 tcctctatcc gcaaaagctc atcagctaac atttgctttc ctttgaggat caattgctcc
     5161 ttcgtcttat ttaattcact gttgatttta ttattagcaa tagagatgcg agcgttcata
     5221 ctctctttag ctaaaaacag caatggtttc aactcaggta tggatagcat ctcctcgttt
     5281 aaatcgacag ggtcattaat ctcatctaaa actacaggtt gaaatttgtc agcaatgatc
     5341 tgttcaaaat ttttttctaa aaaatcagca tctaagtttt tcggtacatc actttcagat
     5401 gtgatttttt cagcttcata aacataattt tctttgtcac tttgggattc gggtttttca
     5461 tcaatttttg gttgttggta ggtttctgtt tgtatttgtg tttcttctat gcttacttct
     5521 tggttttctg cttcggttgg tttgttatca tccacaaaaa gagcttcttt ttcatctggt
     5581 acattttctg ctacggcttc aaattcaact tcttcagaag agttgaaggt ctcagcaatt
     5641 cgttctaatc cattagtagc tacttctaat tgctctactg cgctatagaa gtctgtagct
     5701 tcttcaactt ctgattcaaa cacattagga tcatccggaa taactaataa ttgaccacta
     5761 ctatccataa aacggacacc tgctaatagc ttctctttaa atttttctgg tagatcagct
     5821 acataattca aacttgactt caatagaacg acatacttct cagaatcgag aatagcatca
     5881 tcctcatcta taactccctc actgttgagc ttttgtacat cttcaattac catataattt
     5941 ttctttggta aatctttggt cagcaacgca tcgaattctt tccatacctt tgctttagct
     6001 ttttttgcct tcgcttcttt ttcttctttt ttgtacactt cgagtaattg tggcttcaaa
     6061 gagagtgcaa ctacaggaac tgtttctgcc acataattaa tagattcggt aatatctttg
     6121 aattttgcca ttattgtaaa actccttttt tcagtcaata gttcttttct gtttatctag
     6181 catatataca tatgcttttt cgaatttaat aagcgtttca agtctggctt tttcaatctt
     6241 tttactccca tttcgataat catagaactg gttaacattc atattcatta tctttgccag
     6301 ttcggtacct ttcagactgc tcattaatac ttcgttggcg tgagctaaca ttttttctct
     6361 atcaaaaacc atcttacatt tactttcttc cctcacttct aaactacgct tggagcgtag
     6421 ttttttggta aaaagtaaat tgaacaaatc ggcatattat ccaaatttgt tcaattcact
     6481 tttaacctaa cagttcattt tttggaaatt ttgaaactag atagatacca acaactggaa
     6541 taagtgctga tatgatatta gctttttggt tcaaatcatt acctgtttta gtacccattg
     6601 tgtaaagcat aacggttgta attacaggaa taataaagat tgcaataatc gccccaacat
     6661 attttaatcc atctccccat tttgcatcac caaaaaattt cattgcagtg aatcctggtt
     6721 tcaacgaaaa aacgaatgcc aagaaataca aaacaacttg tactaaagtt ttcatatcag
     6781 gcgtcattcc gctaaccaaa tttttaatag aatcgaacat ataaaaacct cctttttaat
     6841 atttttaata agttaattat atcatcgaca aatcttattt gttcacttgt caatgatcta
     6901 actaagaaaa agacgtctcg atatttacat ctttatgtta tcataataac ataaattttc
     6961 gatgattaaa agagattttc cattaaatta tttcactttt tttattggct aaaaatgctg
     7021 gtttatcaag tttttgttta ga
//
LOCUS       DAZKPE010000105         6987 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000105 DAZKPE010000000
VERSION     DAZKPE010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6987
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.107"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..405
                     /locus_tag="ACG930_002684"
     CDS             <1..405
                     /locus_tag="ACG930_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519800.1"
                     /translation="FLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWI
                     LTIKLSQPFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNN
                     GRAFKLVLTKENQIAGNYSAEITWTLADAPTE"
     gene            473..970
                     /locus_tag="ACG930_002685"
     CDS             473..970
                     /locus_tag="ACG930_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFQ0519801.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            989..1453
                     /locus_tag="ACG930_002686"
                     /pseudo
     CDS             989..1453
                     /locus_tag="ACG930_002686"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            1450..2208
                     /locus_tag="ACG930_002687"
     CDS             1450..2208
                     /locus_tag="ACG930_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFQ0519802.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(2294..3034)
                     /locus_tag="ACG930_002688"
     CDS             complement(2294..3034)
                     /locus_tag="ACG930_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFQ0519803.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3095..4348
                     /locus_tag="ACG930_002689"
     CDS             3095..4348
                     /locus_tag="ACG930_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFQ0519804.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4670..4897
                     /locus_tag="ACG930_002690"
     CDS             4670..4897
                     /locus_tag="ACG930_002690"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFQ0519805.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            5020..5346
                     /locus_tag="ACG930_002691"
     CDS             5020..5346
                     /locus_tag="ACG930_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFQ0519806.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            5414..6127
                     /locus_tag="ACG930_002692"
     CDS             5414..6127
                     /locus_tag="ACG930_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFQ0519807.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            6437..>6987
                     /locus_tag="ACG930_002693"
     CDS             6437..>6987
                     /locus_tag="ACG930_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0519808.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDIL"
BASE COUNT         2454 a         1151 c         1385 g         1997 t
ORIGIN      
        1 tttcttgccc cttccaaact cgattttggt cagatcaaag caactggttt gacacaagaa
       61 gcatttggcc aaatggatat acaggaaaaa ttatggattt atgatcagcg agaaacgaaa
      121 aatccgtgga tcttaacgat aaaattatct cagcctttca caaatgatgc aggattttct
      181 atgcaggatg tcctatattt caagaaagga gaggagtatc aattagtgaa tgaagaagaa
      241 ctggaaattg tcagaggaca aaattcaacg aatgtgcaag cagattattc agaatattta
      301 aataacggtc gggcgtttaa acttgtctta accaaagaaa atcagatagc tggtaattac
      361 tcagcagaga taacatggac attagcagat gcgccgacag aataaagatc aaggaggatg
      421 attgatgaat cgaatatgga ataaaagtca tcgaaacaac tgctctttac ttatgatcct
      481 tctccttgga ttcatccttt ggcagacacc tgtccatgcc tccgaattca attttgcggt
      541 agattttgaa ttaccggcta atcagattga taagaacaaa acatatataa atgtaaggat
      601 ggagcctggg aaaacacagg aaatccccta cacggtcttt aaccgaacag ataaatcagt
      661 aacagttgag acattgatcc actccgctac gacgaattca aacggtgtga tcgaatatgg
      721 agaatcaaaa agtaaatttg atgaaacatt aagttatgat atgaaaaact tagcaaaaac
      781 agtgggagaa ataactgttc ctcctcaaag tgcggtcact gagacacttt cactgaaagc
      841 gccagaaaaa gagctggctg gtgtggtcgc aggagggatc acgtttcaag aaaaaaaaga
      901 gaacgtttct aacaaaagta cagttggtgt cgtcaatcag ttttctcaag tgaaagcaat
      961 cttgatttga aatagcgaaa aagagtcttc cccagatttg aaattaaaaa aagcttatgc
     1021 ggatcaaagc gatggaagaa atgtgattaa ggcgaatctt caaaatccaa atgcttctta
     1081 tatgttcggc ttgactacat cggttgaaat ctacaaaaaa gaaacaaaag agccttacct
     1141 ttcaataaaa aaagaaaaaa tagatgtagc acccaataca aattttgatt tacttgtccc
     1201 attagaagga aaaaaattag ctccgggaca ttatcaagcg gttgtgaagg gtgcttggaa
     1261 agaaaaacgc tggaatctcc ataccgattt tgaaataact gatgatgcag cggaccaatt
     1321 gaatgaaaag gatattgatt taaaaaatca gccagaaaca tttgactggc gatggctgat
     1381 acttgttgga gtcattctta ttggcttatt tgctggatta tttattttaa aagaaagaag
     1441 gaaaaagaaa tgaaaaaaac aattgcatta agtaccgttc tagctggaag tctattatta
     1501 tgtacacaaa gtgtttttgc tgagaataag agctcagcca ctacagaagg aacgatttct
     1561 gtgaccaaac cagatgctgc aaatcctgaa gacgttgttc cagttcctcc tgttgatcca
     1621 aatgatcctg atactccttt tacacctgac gaaccaaatc agggaacatc cggattactg
     1681 acgattgacc aagctccaga tcttgatttt ggaacaatca agttaggtac agcaaaaaca
     1741 gtatatgctg cattacaaag cggaacggac agtactggag cacaaacaca agtacagaat
     1801 ttcgtacaag taacggataa aagcggaaat tatgccggtt ggaaattatc agtcaaacga
     1861 acagaattta ttggtacaac atctgatacg aataaactaa ctggttcaaa ggtgaaattc
     1921 aaaaacgccg tgattcgaaa tagcgcaact aatagcagtg gaatgccatc taccgtttct
     1981 ggaactggcg ctgaaggaat cgaaatccca gcagatcagg cagtagatct agtaactgca
     2041 ggagcaaatg aagggattgg cacatggatt tattcattag gagagaatgt ggaacaaggg
     2101 agacaatcag tggaattatt tgttcctgta tccaattatg ctgtagacaa ctacgtttca
     2161 acattcacat ggtcgttaac agatgctcct acagaagagg aagcgtaaaa tcatatcaac
     2221 gatttcaggg agtggagccg attcaaggcc cactccctga aatctgctat gcttacgtct
     2281 cagctcttat tcatcaactc gaagcagttt tttggaagtc atggaaacgt tcctttgtct
     2341 tttcaaagat ctttcgacca acgagtaagg agtcaccgtt gaaaaattct aacacataat
     2401 gagcagaatc aattttctgc aattgcgata agttgataca gtaagatttt aaaagtaaaa
     2461 agtaagcata cttttctaac tctgtcttca attgttttaa agaagtattc actaatttat
     2521 cttctgtagt tgttttgacc ataacttggt ttttcaaacc tttgatactt tcaatatata
     2581 aaatttcccg aggatacagg acgagacttc cacctttttg atcaataaag attttatcga
     2641 catttacgat ctgctgttct ttccaattga tctgttctag cacttgacga atttgttcag
     2701 ataaattcct gtcttttctg atatatccaa tcggaaggat tttccgattg atgatctcta
     2761 ctgcaaaatt cgtataagcg gtgaaaaaaa caatattact atgtgcattt tttttacgta
     2821 tttgttcggc gacatcaata cctgtgagtg attgcttcaa gtcgatatcg ataaagaaaa
     2881 catcgtgatt atcaatagtg cccaactgga tcaactgatt gatttgagag atagaagtga
     2941 gctgcacgat attctcgata tgatgattga ccaattctct gatgatccat tcgctgtgaa
     3001 actggttatc ttctatgata aaatactttt tcatatgcag gctcctatta aaaaaatatg
     3061 tgtacatttt gaaacaaaac aatggaggaa taagatggtc gcaacagtga cactttattt
     3121 gacctttact ttgattttag atttaggtat ctatttattc ttttcgaaac aactgctagt
     3181 aaaaaacagc tttggttgta tagctttgat ggtggtgaca cttttacttc ctatccctaa
     3241 agtgagcttt ccttacctag ttggcttatt attgatgttt cttttttatt ttactacgaa
     3301 aaacctgttt atcagctgtt tgatcagtaa tctttttttt gctatcactg gactcagctt
     3361 ttttctggtt tttgatctga tggattattt aggaaagaga catcttggaa cagcaagttt
     3421 ttttgcacta cttatcgcat ttattttcta tctattagta aaaagtatag acaaacagac
     3481 gagatttctc aacttgcttt ttacttatcc aactgaacac tattttggag gtatttgtat
     3541 tttattaagc tggggcgtga tttacttggt attgggaagt gttcacttcc gctcatctaa
     3601 ttatctgctt ctatctcttt tgtcgatagt catcagtttt ttttctttgt ttttttccat
     3661 tatgttgatc agtttccaag taaaagaaag acaacatcag gaatcgcttc aactgtatca
     3721 aataaatgaa gaatattacc atcatctaga ggaattcaaa catgattata aaagtctact
     3781 gttttcatta aaaattactc ttcaggaaaa taaaaaagaa acgttggaat ttttagaaat
     3841 attagaagat cattctgcag ctatttttga aaaaccgcaa atacaacagc taacaaatat
     3901 tgtatcccca gctgtcaggg gtgtcttttt aaaatttcta gaaaaagcag aatcggagaa
     3961 aatcccgatc caagtagtta ttcctgtcga agtgaaaaca atcccgattg atctggttgt
     4021 ttttattcgc tgtttatcta tttttatttc taacgcattc gatcatcgtg tagccgatca
     4081 gagtccgatt acgatcaatc tgctggaaga aaaagaggga tcacgtttta gtatagcgaa
     4141 caaggcaaat ccaacgaatt tgacgctatc ggagatggtc aaaagaggaa aaacctctaa
     4201 aaaaaatggc gggttaggtc tatacagtgc gaaaaaaatg ttggatgttt acgaaaatgc
     4261 agaactaaaa atcgaatttt caaaacagaa tcactatttt tttgtagaaa tgtatctggc
     4321 atctagaaag agcaaatcag cctactgact tactgtcaaa ggataagttt gaggaaagtc
     4381 tacacggaga tagagacaac aacacagcat attcaaaaga aacagaagcg tgatgaccgt
     4441 tgtcaccctt ctgtttcttt tgctatgtag ttaaacaaag tagttgacac ttccgctact
     4501 tagtattagt acgaaagtat acttcatgat actaagtaga taagaagtga aaagcggaac
     4561 ccacgatcgt caaaatgcta actgctttgc ttacaccaga taaagggaag agcaatatcg
     4621 cttattttag gcgtggagaa gcaagcaaat ccctacgatc acaaaaaaaa tgctgaccca
     4681 gcagttaaga gagttagaac aagatgaaag tatccatcga aaagcctata accaagtccc
     4741 gcctaaagta gagtactcgc tcaccgaaga aggaaaatca ttaagagaga ttctagtagc
     4801 gttgtctgtt tgggaagaag aacgtatcga aaaacaaaaa gcctcaaggg aagaagacac
     4861 gctactgcat acacatggtg gctacctaaa ttattgattt tctatgacat ttattttaaa
     4921 taaaagaaaa caggagtttt tttaaaagca tcatctattt tttatgtaaa aaaatggtat
     4981 gattaatcaa gtaagaagtg attggaagaa ggcaagcaaa tgaatagtat ggaaaaagtc
     5041 aaccagttta gagatgaacg taattggcga caatttcata acgaaaaaga tttggctatc
     5101 tctatttctt tggaagcatc tgaattgtta gaactttttc aatggaaaac gccggaagaa
     5161 gtaaaagaaa cacaattaga acgaatcaaa gaagaactgg cagatgtatt gatctattca
     5221 tacatgatgg cagacaacct tcacctggat ctagatgaga tcattgaaga aaaattgatc
     5281 aaaaataatt tgaaatatcc tgtagaaaaa agcgcaggtg tacgaaaaaa atacacagag
     5341 ttgtagaaat gtgtcattcg gctgttggaa agagcaaaag aaaaacagta aaatgagtct
     5401 ggagggagag aaaatgaaaa aaaaaggaaa agcaaaaaga tggctagtca atatcctctt
     5461 gttcctcttg ttattagtag gactagcttt gattttcaat gaacagatca aggattattt
     5521 tgtcagagag acaggagata aatatgctat agcgaatgta acaaaagaag atctgaaaaa
     5581 gaataacgat aaagatgtca gttttgactt tgatgcggta gaaccaatga cgacagaagg
     5641 ggtcatgagg tcgcaaatga gaggaacaga tctaccagtg attgctagta tcgcagtccc
     5701 ttcagtttca atcaatttac cggttttcaa aggcttggat aatacgtcac tactttacgg
     5761 agcaggaaca ttatctccag atcaagaaat gggaaaagga aattatgcct tagcaagcca
     5821 tcgtgcaacg aaccctgaat tgctgtttac accgctagaa aatttagaga tgggtgccaa
     5881 gatctatttg acagatttag aaaatgtgta tacatacaaa acatttttta aagaaaaagt
     5941 tgctcctaca gatacccaat tactgaatga agtcgaggga aaagaaattg tcacactaat
     6001 tacttgtggc gacatggacg ccgtcacgcg actagttgta caaggagaac tggaaagtgt
     6061 tacatcgata aaagatgcga cagatgatat gagatctgct ttcaatctag agacaaaaac
     6121 attttaggat actgggacat aagtcgttac agattaaaaa cagccaaagg atatgaatcg
     6181 ataaggaaaa accaatttgc tgaaaaaaag agaaacgcaa agaggtgcat ctctgatttg
     6241 gttgttttct agatagactt gtgttccagt ttttttattt tttatatgaa aaggcttgca
     6301 taaataaaaa ttcgatggta tgatgatttt gaataagaaa tggattgtta ctgtacggca
     6361 ggcaaaacca gaattcagct aagaaacagt aggcgaattc taggtttttt tatttttctt
     6421 gagagggcga agcaaaatga aaattgataa aattttgaat aacaatgtcg tcatttcgaa
     6481 aaatggattc ggggaagaag tcgtttgtat gggaaaagga ctagcttttc aaaaaaagat
     6541 tggggacgag atttcgccag aagcggtcca aaaagaattt gttttaagag attcttttgc
     6601 taaaaaccaa ttccagcagc tgatggctga tattccggca gaggagatcg aatgggtcaa
     6661 acaagtagtc gaactggctg aagataaact aaaagttgaa ttttcgccta atatttatct
     6721 gacattgacc gatcatcttc attatgcgat cacacgagca aaagaaaata tccaactgcc
     6781 taatccatta ttatttgaaa caaaaaaatt ttatccgaaa gaatatcaag cagcgaaaga
     6841 ggctcttttg ttcgtgaaac aaaagacggg tgtggaactt tctgaggatg aagccggttt
     6901 tattgccttt cattttgtga atagccaaca aggaaacgaa gacatgcaag tgacgatgac
     6961 cgctaccaca atggtaagag atatact
//
LOCUS       DAZKPE010000106         6965 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000106 DAZKPE010000000
VERSION     DAZKPE010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.108"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..2131
                     /locus_tag="ACG930_002694"
     CDS             56..2131
                     /locus_tag="ACG930_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HFQ0519809.1"
                     /translation="MKEVINIESNYFSRKFDDELLIIEAWGENAIRIRSFVDMNYEDR
                     QNSLIDKPNSLNKVIINQYENKTELINGKIRAVLDHRDRLTFYNEKNDVLLKEYIRLR
                     AVKHDDGGEDAGSVEVTKDFNSTLKLKSREYRSNMDGKFQVTTRFESDPKEKIFGMGQ
                     YQHSYLDLKNTVLELAQRNSQVSIPFYISSLGYGFLWNNPGIGEVSFAKNITRWKMYS
                     SDYIDYVIISGNEPKEILRNYSNLTGKVPKMPDSLLGLWQSKLRYRSPEEVMDVVEKY
                     HKRGIKLSTIAIDYFHWPKQGEYCFDEEYWPNPEKFLKTLKTDYGVEPIISIWPTVQT
                     DAENYEKYLENGYLVKVNRGVRLTMQIQGNTIFIDMTNSEARKYVWSLIKKNYVDKGI
                     NYFWLDVAEPGYSVYDFDNYRYKKGTDLYSGNLYPIDYLSMIYEELSNEQPVITLVRG
                     GWAGAQRFGALLWSGDIDSSFEAFRNQVNTGLNVGLAGIPWWTTDIGGFHGGNPEDPE
                     FRELLIRWFQYATFSPILRMHGDRLPHSKPLSDHGGGSMVTGAPNEIWSYGIEVEQIL
                     TKYIKIREALKPYISTLMDKAHRFGDPIMRTLFYEYPSDNNTWAVEDTYLFGDTFLIA
                     PIVNYKETVREVYLPINENWTNIWTGEEYDGGQTLDVEADISMIPVFIKTNQKDKFSK
                     LLSIIKEEI"
     gene            2131..2916
                     /locus_tag="ACG930_002695"
     CDS             2131..2916
                     /locus_tag="ACG930_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0519810.1"
                     /translation="MEISVIQLGLIVLYGFFINFEKNSTMFGTYQPVTAGFVTGLILG
                     DIKTGLFIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTGQESSVGISIGIPV
                     ALLMVQLDIIRNTIGIWMVHKAEAGVKRGDYSMISKMQMFGVFLTAATTGIPVALAVI
                     FGPSLINTILAHTPEWLTNGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVMSVY
                     LKMPLLGVALIGAAIALIIYKKNSQNVINNTVVNTIGGMDEDE"
     gene            2909..3721
                     /locus_tag="ACG930_002696"
     CDS             2909..3721
                     /locus_tag="ACG930_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFQ0519811.1"
                     /translation="MNSLETTKLGVNSKIKKSVLWRWFFTSSVSSNYEKMQALAYCYA
                     VLPFLKVTYKNKPEALQKAVLNHLQFFNTNPWVAPYILGINIAMEENSDENTEEAVTS
                     IKTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPVGIILWIAVSVALKMISIPL
                     FRIGYTSGTKLITTIEKSLKLLTESTSILGLMVVGALIPSVVKTNVVLDFKQGDFSMR
                     GQEILDQIMPGLLPALLVGLVYWSLKKNVKPIYLILGVMVLSIVLATLGILK"
     gene            3741..4223
                     /locus_tag="ACG930_002697"
     CDS             3741..4223
                     /locus_tag="ACG930_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFQ0519812.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDTVANND
                     IQKQVLRMAVPAGISSSIITEEKAITNIKNGKYEGQNVLLIVKSPVDLLSFIENDLQI
                     DRINVGNMSNRKGTTVLRPNISVTNEERNAFEKLLNLGVEITTIMTPDDKKTYLKDIL
                     "
     gene            4238..4642
                     /locus_tag="ACG930_002698"
     CDS             4238..4642
                     /locus_tag="ACG930_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFQ0519813.1"
                     /translation="MTNEIILMSHGLMAEEILNSAKMILGNQINYPVVSMTQNDGIEG
                     TINKLNKILEETSDIRNIIILVDLMGGTPANVAMMKASMDKRIQVVTGMNLGMVLESY
                     FKINEEKLAEHLIEIGKSSIKIPEIQMDGGEE"
     gene            5228..6418
                     /locus_tag="ACG930_002699"
     CDS             5228..6418
                     /locus_tag="ACG930_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFQ0519814.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFKGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGAFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
BASE COUNT         2447 a          956 c         1387 g         2175 t
ORIGIN      
        1 acaattgcta gtgttgtaat aagagttaac taattaagaa gaaaaggaaa gtgggatgaa
       61 agaagtgata aacattgaat caaattattt ttcaagaaaa tttgatgatg aattactgat
      121 tattgaagca tggggggaaa atgctattag aatacgttca tttgtagaca tgaactatga
      181 agatcgacaa aactccttaa ttgataagcc taattcccta aataaagtga taataaatca
      241 atatgaaaat aaaacagaat taattaacgg gaaaataaga gcggtactag atcatcgtga
      301 tcgtttaact ttttataatg aaaaaaacga tgtcttacta aaagaatata ttagattaag
      361 agctgttaaa catgatgatg gtggtgaaga tgctggttca gttgaagtta caaaggattt
      421 taattctaca ttgaaattaa agtcaagaga atatcgttcc aatatggatg gtaaatttca
      481 agtaactact agatttgaat cagatccaaa agaaaaaata ttcggaatgg gtcaatatca
      541 acattcttat cttgatttga agaacactgt tttagaatta gcgcaaagaa actcacaggt
      601 gtcaattcca ttctatatat ctagtcttgg atacggtttt ttatggaata atcctggtat
      661 tggagaagtt tcttttgcta aaaatataac tcgatggaaa atgtattctt ctgattatat
      721 cgattatgta ataatttcag gaaatgaacc aaaggaaata cttagaaact atagtaatct
      781 aactggaaaa gtccctaaaa tgccagatag tttattagga ttatggcaga gcaaattacg
      841 atatagatca ccagaggaag tgatggatgt agtagaaaag tatcataaac gtggaataaa
      901 gctttcaact atcgctattg attattttca ctggccaaag caaggagaat attgttttga
      961 tgaggaatac tggcctaatc cagaaaaatt tttaaagact ttgaaaactg attacggagt
     1021 ggaaccaata atctcaattt ggcctacagt acaaactgat gcagaaaatt atgaaaaata
     1081 tttagaaaat ggttatctag taaaagttaa tcgtggagtt cgattaacca tgcaaattca
     1141 aggaaacact atttttattg atatgacaaa tagtgaagct cggaaatatg tttggagtct
     1201 aattaaaaag aattatgttg ataaagggat taattatttc tggttagatg tagctgagcc
     1261 aggatattcc gtttatgact ttgataatta tcgttataaa aaggggactg atttatatag
     1321 tggtaattta tatccaatcg attatctttc aatgatttat gaagaattaa gtaatgaaca
     1381 gcctgtaatt actcttgtta gaggaggatg ggctggagca caaagattcg gtgcattatt
     1441 gtggtctgga gatattgatt ctagttttga agcatttaga aatcaagtta atactggact
     1501 aaatgtaggt ttagcaggga ttccctggtg gacaactgac ataggtgggt ttcatggcgg
     1561 aaatccagaa gatccggagt ttagagaatt gctaattcgt tggtttcaat atgctacttt
     1621 ttcaccaatt ttaagaatgc acggtgaccg attaccccat agtaaaccct tatcggatca
     1681 tggtggaggt tcgatggtta ctggtgcacc aaatgaaata tggtcatacg gtatagaagt
     1741 tgagcagata ttaactaagt atataaaaat acgtgaagcg ttgaaaccgt atatcagtac
     1801 tttgatggat aaagctcata gattcggaga tccgatcatg aggacgctat tttatgaata
     1861 tccttcagat aataatactt gggctgtaga agatacttac ttatttggag atacgttcct
     1921 aattgcaccg attgtaaatt ataaggaaac agtaagagaa gtttacttac caataaatga
     1981 aaactggacc aatatatgga caggtgaaga atatgatggc ggacaaacgt tggatgttga
     2041 agcagatatt agtatgatac ctgtttttat aaagacaaat caaaaagata aattttcaaa
     2101 actattaagt ataattaagg aggagatcta atggagataa gtgttattca acttggttta
     2161 attgtgttat atggtttttt tattaatttt gagaagaatt caacaatgtt cggaacctac
     2221 caacctgtaa cagcgggatt tgtaactggt ttaatacttg gagatataaa aactgggctt
     2281 tttattgggg gaaccttaca attattgtct ttaggaatta gtaattttgg aggagcttct
     2341 ataccagact atcaaactgc aagtattgtc gcaactttta tcaccataac aactggtcag
     2401 gaatcttcgg tagggatttc tattggtata ccagtagcac tattaatggt tcaattagat
     2461 attattagaa atacaattgg tatttggatg gttcataaag cagaagcagg tgtaaagcga
     2521 ggagattata gtatgatctc caagatgcaa atgtttggag tattcttaac ggcggcaaca
     2581 acgggcatac cggttgcgtt ggcagtaatt tttggaccat ctttaattaa tactattctt
     2641 gctcatactc ctgaatggtt aacaaatggg ttaacagttg ctgggggatt attaccagct
     2701 gttggtattg gtttattgct tcgatactta cctgcaaaag aatatttcag ttatcttgtt
     2761 atcggttttg taatgtctgt ttacttaaaa atgccattat taggagtagc attaataggc
     2821 gctgctatag ctttaattat ttataaaaaa aatagtcaga atgtaattaa taataccgtt
     2881 gttaatacaa taggaggtat ggatgaggat gaatagcttg gagacgacaa aacttggtgt
     2941 taattccaaa attaaaaaga gtgtattatg gagatggttt tttacaagct cagtttcttc
     3001 aaattatgaa aagatgcaag ctctagcata ttgttacgct gtattaccat tcttaaaagt
     3061 tacttataaa aacaaaccag aagcgttaca aaaagcagta ctaaatcatt tacaattttt
     3121 caatacaaat ccttgggttg caccgtatat tttaggtatt aatatagcta tggaagaaaa
     3181 ttcagatgaa aatactgaag aagcagtgac atcgattaag acaggactta tggggccagt
     3241 agctggatta ggtgatagtc tatttgtagt tattccatgg actatatttg gggctattgc
     3301 agcaaatatg gcaattgatg gtagtccagt aggaattatt ttatggattg ctgtaagtgt
     3361 agctttaaag atgataagta taccattatt tcgcataggc tatacttcag gtacgaaatt
     3421 aattactact attgaaaaaa gtttaaaact tttaactgaa tcgacttcaa ttttaggatt
     3481 aatggttgtt ggagcattaa taccatctgt tgttaaaaca aatgtcgtct tagattttaa
     3541 acaaggtgat ttttctatga gagggcaaga aatactagat caaataatgc caggattatt
     3601 acctgcactt ttagttggtt tagtttactg gtctttgaaa aaaaatgtaa aacctattta
     3661 tttaattctt ggtgtgatgg ttctgtctat tgttttagct actctaggca ttttaaaata
     3721 aatgatagga ggaaattttt gtggaaatga agggtataaa aaatattaga attgacgatc
     3781 gattaattca tggtcaagta gctacaatgt ggagtaataa attaggtgtg actcgtttga
     3841 tggttgtaaa tgatactgtt gcaaataatg atatacaaaa acaggtgcta aggatggcag
     3901 tccctgcagg aatcagttct tcaattataa ctgaggagaa agcgattacc aatattaaaa
     3961 atggaaaata tgaagggcaa aatgtgcttt taatagtcaa atccccagta gacttattat
     4021 cgtttatcga aaatgattta cagatagata ggattaacgt tggcaacatg tctaatcgaa
     4081 aaggaacaac ggttttacgt cctaatatta gcgttactaa tgaagaaaga aatgccttcg
     4141 agaagctatt aaatcttggt gttgaaatta ctacaattat gacaccagac gataaaaaaa
     4201 cttacttaaa agatatttta taaggggaat aagtgcgatg actaatgaaa taattttaat
     4261 gagtcatggt ttaatggctg aggaaatatt aaattcagct aaaatgatac ttggaaacca
     4321 gattaattat ccggtagttt ctatgacaca aaatgacggt attgaaggaa caataaataa
     4381 attgaataaa atactggaag aaacaagtga catacgaaat attattatat tagtagacct
     4441 aatgggagga acacctgcaa atgtagctat gatgaaagca agtatggata aaagaattca
     4501 agtagtaact ggaatgaatc tagggatggt attagaatca tactttaaaa ttaatgaaga
     4561 aaaacttgct gagcatttaa tagaaatagg taaaagtagt attaaaatac ctgagataca
     4621 gatggatggt ggagaagagt aattataatg aaggaagaat agttctgtta atctcaattg
     4681 aaaaagttta aatcaaaaca aaaggaaatc tattttcgat attaatatga ttcgttttct
     4741 acataatatc aaaattagat acgaagccat agtaagaaat atgttttttt cattataatc
     4801 ttaaataatt aatactagcg aaatagagga atgttaaaag ggctcttttt ggaatagcac
     4861 ggtatagcta gtgcttgaac tgctataaaa accaaatagt taaatagtaa agcaataatg
     4921 gttcgagtgt actatttgga ggacaatcta agattgaaga tgctttcaag tataagtggt
     4981 attttcaatg agacggttag gaaattagtg ccagagtagg tactaattct agatgtaaca
     5041 atcttaacag cggtgggata tgatctatat gcaaatatta tatagttgtg ttaaagtttt
     5101 tttgatatat atatgaatgt tgtccaatca aatgagagtg taaaatattt tgtgtaaata
     5161 gaaaaaagga agtcccttct gtagaataga gttaccacaa cacattcaca gaagagagga
     5221 cttccctatg aacgatttta ctacagaaat tctaaagact ctagcgaaca aaggcgattt
     5281 gaatgaatta ttccgtgtcc atttggagaa agcagtcaat acgcttctca aaacggagtt
     5341 aacggctttc ctagattacg aaaagtatga tcgcattggt tttaacacgg gtaattctcg
     5401 taacggctcc tatgaccgta cggtcaagac cgagtatggg gaacttcatc tccagattcc
     5461 gcgcgaccgc aatggtgagt tcaagcaaca gactgttcct gcttatagac ggacgaatga
     5521 cacgttagag gagaccgtca ttcacctctt ccgaaaaggt attaccatgt cggaaatcgc
     5581 agacttgatt gagaaaatgt atgggcatta ctacacgccc caaaccatgt ccaatataac
     5641 aaaatcattt acagaagagg taacggcgtt taaagggcgg gagcttcatg accgttatgc
     5701 tgctatttat atggacgcaa cgtatattcc gttaaagcgg aaaaccgtcg ccaaggaagc
     5761 tattcatatc gcagttggca ttcgcccgga cggatcaaag gaagtattga gctatgcgat
     5821 tgcaccgact gaatccatca cgatttggga ggaaatttta ttggaccttc aagagcgcgg
     5881 tttgaaaaat gtcctcctgt tcatcacgga tggcttaaag gggatggtag gagcgattag
     5941 tcggttctat cccaaagctc gttttcaaca ttgttgtgta cacgtttccc gtaatatcag
     6001 tcacaaagtg cgtgtcgatg atcgtaagga agtctgtgat gattttaaaa tggtgtatca
     6061 agcctcatct aaagaggtgg cgttggaagc acgtggtgct tttgcggaaa aatggaaaac
     6121 cagctatcca aaagtggttg aatcgattct ttcgaacgat cacttgctca ctttctatga
     6181 tttccccttg gccatacgca agagtattta ttctacgaac ttgattgaat cctttaataa
     6241 gcaaatcaag aaatacagcc accgcaagga acagttccaa aacgaagagt cgatggaacg
     6301 tttcttagtc tcgtcttttg atacttacaa ccaaaaattc ctaggtcgca gtcataaagg
     6361 ctttcaacag gccgaaggcg aacttgaaca aatgctaagc caactgattg agaattagaa
     6421 acaatctgca gtagggaaga atcatttaca caaaattatt gacgctcccc tttgttgtta
     6481 atcttaggac ttgaaatatg atttcttttc caaaatttat tatcttattt taattcttcc
     6541 atacatttaa taatctatag ataaaaaaag agataattta gatcattttt tgcaatataa
     6601 agcaaatttg ttgagctaag atgttggtat ttctataata ggttcaggga tatcccaata
     6661 tcactctcta agggcaactc aggggaagga gttgcccctg aaaatgtata ttagaattat
     6721 caaagcaaaa aataagcata ttaacttatt ttttataatg ttgtagcgaa aaatatagcg
     6781 caagcttaaa attaagttct caaaaagtag aaatagctgc ttcttatacc atgattaaat
     6841 gaataaagta tgctgtcact ttatgggaat ttcgggatga aaatagatac aacgtgtatc
     6901 agcatatttt ttctttttat attttttata gctttttata ctttttctca gtccatcaga
     6961 atcta
//
LOCUS       DAZKPE010000107         6824 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000107 DAZKPE010000000
VERSION     DAZKPE010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.109"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(368..1486)
                     /locus_tag="ACG930_002700"
     CDS             complement(368..1486)
                     /locus_tag="ACG930_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519815.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1719..1841
                     /locus_tag="ACG930_002701"
     CDS             1719..1841
                     /locus_tag="ACG930_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519816.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1957..3264
                     /locus_tag="ACG930_002702"
     CDS             1957..3264
                     /locus_tag="ACG930_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFQ0519817.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3383..4582
                     /locus_tag="ACG930_002703"
     CDS             3383..4582
                     /locus_tag="ACG930_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFQ0519818.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4609..5877)
                     /locus_tag="ACG930_002704"
     CDS             complement(4609..5877)
                     /locus_tag="ACG930_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFQ0519819.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(5937..>6824)
                     /locus_tag="ACG930_002705"
     CDS             complement(5937..>6824)
                     /locus_tag="ACG930_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFQ0519820.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT         2069 a         1401 c         1178 g         2176 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aataagaaaa acatctttcc atcggaaaga
     3301 tgtttttttg ctttttctag tttaaataac agcttttttc atctattttc gttatactgt
     3361 ataagaaaaa ggagttgaat ttatgaatct aaccagagat ctgatctttt tagttctcta
     3421 tcttattggg gtattctcta tcgtttattg gcgaaaacag aagaaggatc cttccttgtt
     3481 cttttacggc agtacgtgga catttacggt aatcttaact tattttgtcg tgttggaaat
     3541 tttttattcg accttttatt ttttgattcc attgttgttc tttagtatct ttgctttttc
     3601 ttatttcaca gaaaaacgaa ggctactgaa tggtctttta ttcaatgttt tactcatcag
     3661 tttcggcatc tacttgtttg tcttgctgta tgaaacgcaa aatatttttc ttggcggact
     3721 gatcgccttg atcacgattc cattgctact tgtcctttta tttggtattt atggattgat
     3781 tgtttttctt ttttggaacg gggtcacagt tttacgtaga gaatcgcatt cattagctaa
     3841 tcttttaacg ttgatactag ccatttttct tacactgttt cttgtttttg actttttctt
     3901 gttaaaatat ttgccgcaat ggataaatgc tttgtttttc tgcgttcccc tgatcttgat
     3961 ctatctattt atcgtattct acaacttttt gactgtctca ttcttgtatc agttcaaccg
     4021 gcctcgatac aatcaagact tcatcgttgt gttaggcgct ggattgatca atggagaaac
     4081 agtttctcct cttctagcca agcgaatcaa taaggcaatt gctttttatc gggctcaaag
     4141 ccgtgctaca ttaaatccgc ccatcttatt gatgtctggc gggcaaggag cagacgaaaa
     4201 agtaccagag gccattgcga tgaaacaata tgccatggaa caaggaatcc ctgaaagaga
     4261 cattcttgtc gaaaccaatt cgacaaccac tttggaaaac atgctctatt caaaggaaat
     4321 catggatcag caaatgaaag ggccataccg cgcgatcttt agttccaaca attaccacat
     4381 ttttagagcc ggtctttatg cgcggcaagc caaattgaaa gcaaatggta ttggtgcaaa
     4441 aacagctttc tactacttgc ctaatgcgtt tttaagagaa tacctcgcca tcttgatgat
     4501 gaacaaaaaa agacatatga tcatttgcgg attgcttttc gcaggctccg cattcttatc
     4561 gctgattact ttacttttct aaaaaaacaa ggtgtgacaa aacatatgtc acaccttgtt
     4621 tttttctttc attctcttaa ctattggcaa aaagagtatc ccttttttga ccgctacttg
     4681 ctgagcagaa taaataccgc tgttgcctga acacataaag ctgatcaagc agatcataaa
     4741 gaagtatact gccgcttgtg aaccgaacaa ttcgatcccc atcacaaagc aggcaatcgg
     4801 tgtatttgtc gcaccagaaa atactccgat aaagcccaat cctgcaagaa aaggaacaga
     4861 aacatggagc aaaggcgcta gtgctgcacc aagcgttgca ccaatttcaa acaatggtgt
     4921 cacttctccc ccttgatatc ccgcgcctaa agacaaaact gtgaagaata acttcccaat
     4981 aaaatcatag acatgtgcct gtccattaaa tgattcttga agtaacggaa gactcaatcc
     5041 gagataacgt tgtgtttgca aaatcaatgc tgctgccaca actacagctc cacctatcgt
     5101 atttcgacaa acaggatgag gaatccattg tgcatatcgc gcttttaaaa agacgatcga
     5161 acggctgaat acccaaccaa tcaaaccaaa agcaatccca gcaacaaaaa ctttgaagaa
     5221 cagcaacata ctccattcag gaatcacacc catttggtaa tgtagatgag aaacaccata
     5281 gctttctgtc atgaaatttg caaacagtgc agcaaagaag ctagggaaga tcgcttctgt
     5341 tcggactttc ccgattgcca acacttctaa tccaaataat gttccagcta aaggtgtgcc
     5401 aaatacagaa ctaaaacccg cactgattcc actgataatc aagatttccc gttctgattt
     5461 atccaatcgg aacaaacgtg ccgtattatc tgctaacgct ccccccattt ggactgctgt
     5521 tccttcacgg ccaacagatc ccccaaataa atgggtagtt atggttccaa acagtgtaag
     5581 tggaataagc cgcaacggga ttttttcttc tccaccattt ccttgatcga tcactaagtt
     5641 gtttccacga ctagaaagtc cgccgtgata cgcatagaga taagcaaaaa gcgcaccact
     5701 aactggtagt agacaaagga gccaaggatg tgatagtcgg atatctgtca caactgtcag
     5761 gctatttaag aaaaaagcag acaagctccc catgaatata ccgagaatcg ctgtgatcac
     5821 cagccacttc agcatataca ctaaaatgcg tactggactc ggtaattgtt tttccataaa
     5881 aaattcctcc tcaataaaaa aacgcctact aaatgaactg aaccccaaaa gttgaactat
     5941 ttaatggact gtttccgata ttctactgga gatagtccat ttaactttag ttttatcctt
     6001 ttgttattat accacctaat atactcattt aatttacttt gaaatatctc aattgatcgg
     6061 aatttttctc gataaaaaaa ctctgattta agcacaccaa aaaaattttc tattacagaa
     6121 ttatctaagc aatttccttt tctagacatg ctttgaataa tgttattctc ttttaatttt
     6181 ttttgatatt gtggcatctg atactgccat ccttgatctg aatgtagaat cagtgaaccc
     6241 tcagttccct tttttttaat tgcttgttga agcatttctt caatcagttt atatgttgga
     6301 ctagttgata tactataact aattatttct ccgttaaata aatcaagtat aggagataga
     6361 tagatttttc ttccttttat cttgaattca gtgacgtctg tcacccattt tttattgggt
     6421 gtatctactg aaaaatttcg ttttaacaca ttcttggcaa tttttcctac tgttccttta
     6481 taagatttat atcgctttat tcggatttga caggtaagtc ccatttggga cattaatttt
     6541 ctaactgttt tatgattgat tgtatatcct ttcatcttta acgctaaagt gactctacga
     6601 taaccataag agtttcttga ttcttttaca atcgctgtaa tttcttgctt tatcttgcta
     6661 tatttatctg gcttatctaa tttttttacc cagtaataat aagttgactt cgctaattgt
     6721 gcaattgaaa gtaatagatt caatttaaat tcttttttga gctgaaggat tgttttaacc
     6781 ttgatttctt cttgctcaaa tcttgttctt gaatcaaggt ttct
//
LOCUS       DAZKPE010000108         6733 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000108 DAZKPE010000000
VERSION     DAZKPE010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.110"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..546
                     /locus_tag="ACG930_002706"
     CDS             <1..546
                     /locus_tag="ACG930_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0519821.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
     gene            complement(716..1678)
                     /locus_tag="ACG930_002707"
     CDS             complement(716..1678)
                     /locus_tag="ACG930_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0519822.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1680..3119)
                     /locus_tag="ACG930_002708"
     CDS             complement(1680..3119)
                     /locus_tag="ACG930_002708"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFQ0519823.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLIHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEENLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3304..5250
                     /locus_tag="ACG930_002709"
     CDS             3304..5250
                     /locus_tag="ACG930_002709"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFQ0519824.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5514..6386
                     /gene="scrK"
                     /locus_tag="ACG930_002710"
     CDS             5514..6386
                     /gene="scrK"
                     /locus_tag="ACG930_002710"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFQ0519825.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2163 a         1149 c         1203 g         2218 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa
      301 ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca
      361 cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac
      421 tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg
      481 ataaaacaga aattaaactg gcaaagtccc gtccaatttc gtaaaacaac cgtaacagtt
      541 gtgtaaaaat atcattttag agcatgaaaa aaggagtgga tttctccact ccaaaaaagt
      601 ctaacttttg ggggtcacta caagttgaca actccttttt gtttacaaat caattggata
      661 tctacaaatt gtattttcta acgaatttta tagacattaa aaaattaatt taacgttaaa
      721 tacttcctcc agaaagtatt gagattggta aaatataatc cttatttgtc ttttcgcctt
      781 taattttttt cagaagaata tcaacaataa gacttgcaat ttcatcaatt ggttgtctta
      841 ttgttgtcaa ttgtgggaaa aatttctcaa taaaagaggt accatcgtat ccaataattt
      901 ttaaatcttc tgggatatta agtttaagtt gatgagcaat tttcatagtg agaatggctg
      961 ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt tataatagtt gactttattt
     1021 ccatttcacg acggatagta gacagattat taggaatttt gaaaattttt ccatttggat
     1081 tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga atccgtgtta tcatttcctg
     1141 taatcataat ggtattttga caaccatttt tttgtaaagt cttagctgca agttttcccc
     1201 cttcaaagtt atctgaagaa acaatggaaa cattaggagc taaatttcta tcaaaagcaa
     1261 caataggtgc tctcacacgc tcataatcag caattccaag attatggctt gatgagatta
     1321 tgccatcaac ttggttggct tcaagcattt caatgtattc tctctcttta gcaggatcat
     1381 tttgactatt gcaaataatc gttttatatc catgtttaaa taactctatt tcgagatact
     1441 caatgagttc agagtaaaag atattactaa tattaggaaa aataagacca ataagctgag
     1501 gtgactttcc ttgaagtcca cgtgctaaat tatttggttt ataaccaaga gttttcatag
     1561 cttcatgaac tttttgtttt gttttttctg ataaatatcc cttattatta atgacgcgtg
     1621 aaacggttgt tgggctaact ccagctaatt cagcgacatc agttaatttt gctaccattt
     1681 taatatttta attcaaagta ttttccagta ggttcgcctg atttgatttg aataccattt
     1741 tggtgatttt cagggaatac acgactagta aacacttttt ctcctttatt aataaaaatc
     1801 tcaatgattg agttatctac aaaaatgtta gcagttgttt ctttagtatc aattgagcat
     1861 tcacgaatcg taccaaagtc agtggcatat tgaatgcctg ctttgctgcg atctaaaata
     1921 atttttcctt ctttggtatc tacaatcaag ctaagtccat ttcctttact atcagagaaa
     1981 agaagtaact ccgatttctg atttggagga aaagttagtt caagctcata agtattattt
     2041 gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta atgatgtaat agcttctact
     2101 ggatattggt aaagtttacc atcttttatt gaaagttctt ttacaagact cattgctccc
     2161 tgataatcat acttatcagt tggataatcg atatcaggta gtccaatcca actgacaatc
     2221 agagcacgac catcaggagt attgaatcct tgagtcgcat acgcttcaaa tccataatca
     2281 agattttgaa tttctgaagc gcccacaagt tttacttttt ctatgtcaag cgattgacag
     2341 atcttaaaag tattcggata gatattccca taatttagct cagatttatc caacccttga
     2401 ggacaataaa tgagaacagg ttttttgtct acaaatacta gatttggaca ctcaatcatg
     2461 tattctgaac cagtgccgcc aaaatcaagg ttgccaactt cctcccatgt ttccacgtta
     2521 ttgtcatccg ctttgtaaag tttgataaag cctgattttt ctaaattttg tgctccaaca
     2581 atcgcataca attgtccttc ataattaaac atttgtggat cacgaaaatg atcagttaca
     2641 tcagcaggtt tatgaataag aacattctca cctttcgtaa tgttgtagtc tttatccatc
     2701 catgctccga tttgaagtgt atcacgttcc caattttcat ttcgaacgtt tcctgtatag
     2761 agtaagaata gattctcctc tatttcatat gcagaaccgg aataagcgcc gtggctatct
     2821 cgttttgtgt ctggaagaag ttctgctcct gttacatgaa aatgaattaa atcatctgat
     2881 tcattgtgta cccattcttt caacccatga gcagctccaa atggccaatt ttgataaaaa
     2941 agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat cgtttaacaa tcctgtttta
     3001 ggttcgatat gatagctagc acgccaaggt gatcgtttta cattatcctt aattttatcc
     3061 atctcatctt tagtccaatc agaataagca cgatatcgta tttctcgagg taagttcata
     3121 ttttactcct tcaatttatc tttttacaac tagtatggta aacgttttcc gttgaaaaat
     3181 caatcatttc atttaaaaaa ataaactata tgacaaacgt ttgacatatt tttaagatat
     3241 gctaaaataa atttgcattt cagtgaaccg ttttcacgta aaaataaaaa aggagtgatt
     3301 cgaatgaatt acagtaaagt agcttccgac gtaatacaag cggtcggaaa agataacctt
     3361 attgcagctg cacactgcgc tacacgtctt cgtctcgtac taaaagatga cacgaaagtg
     3421 aatcaaaaag ctttagacga aaatccagat gtgaaaggca catttaaaat tgatggacaa
     3481 tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt atgacgaact tatcaaaaaa
     3541 actggacttt cggaaatttc aacagatgat ttaaaacaaa ttgctagtaa agataaaaaa
     3601 ttcaacccca ttatggcatt aattaaatta ttatcagata tttttgttcc aattatacct
     3661 gcccttgttg caggtggttt attaatggca ttacaaaact ttttaacagc tgctggactt
     3721 tttggaccaa aatcaattga agaaatgtat cctgcgattg aaggtatttc ctcaatgatc
     3781 caactgatgt ccgctgcacc attcatgttc ttaccaattt tagtaggtat ttcagctgct
     3841 aaacgttttg gagcaaacca atttcttggt gctgcaattg gtatgatcat gacaacacca
     3901 gatcttggtg gctcaactga atattggaat atttttggtt atcatgtttc acaaacaaac
     3961 tatgcttatc aagttattcc agttttagca gctgtttgga tattatctat attagaaaaa
     4021 ttctttcata aaaaattgcc atcatctatt gactttacat tcacgccatt attatcagta
     4081 atgattactg gatttttgac tttcacagtt attggccctg taatgttatt gttgtctaat
     4141 ggaattacag acattattgt ttggctatat aacactactg gatttattgg aatgggtatt
     4201 tttggaggaa catattcact tatagtcatg actggtttac atcaatcatt tccagctatt
     4261 gaaactcaat tactttcagc gtggacaaat ggtatcggac atggagactt tatctttgta
     4321 gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat ttgccatttg gttcttaact
     4381 aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg tctcagcact tcttggaatt
     4441 acagagcctg ccttgttcgg agttaactta aaataccgct ttccattctt ttgtgcttta
     4501 attggttcag gaattgctac agcagtagca ggattactta aagtagttgc tgtttcactt
     4561 ggttcagcag gtttcttggg atttctttca attaatgcaa catctattcc attttacgta
     4621 ttgtgtgaat tgattagctt tgtagttgct tttgcaatta cttacttcta cggtaaaaca
     4681 aaagctgctg gtatctttaa agcagaagaa attgctgaac aaacaccagt taattcttca
     4741 aaagtagcaa caacagatcc aatatctact gatgttgaat caacacaaac aaaagtttca
     4801 tcagaaacaa ttgttagtcc catttctggt aaagtgatta gtctttcttc agtaaatgat
     4861 ccagtctttt catcagaagc tatgggaaaa gggattgcca ttaaaccaaa tggaaacacg
     4921 gtccattctc cagtagatgg tactattcaa ctcacgtttg aaactggaca tgcttatggt
     4981 attaaatcaa ataatggtgc tgaagttcta attcatattg gtattgatac tgtatcaatg
     5041 ggaggaaaag gatttacaca aaaagttact actaatcaaa aagttagaaa aggcgatatt
     5101 cttggagcat ttgaccgttc aatgattgag aaagaaggtc ttgatgatac aacaatgatt
     5161 attgtgacca atacttcgga ttattcagaa gtaaatatag tagctgaaaa tacagtcact
     5221 gagggtactg atttacttga aatcaaataa atatatttcc ctgagtaaag atggaatttt
     5281 ctttccaaaa tcaaataata tagattaatc aaatatttga gaataacatt ttatttaatc
     5341 ttttcatata tcaattgtat gaaaaattat tagaatttta aaaaatgata aaaattcaaa
     5401 aagaaaaaat agtagttatt tacttgtcat gttactaaat aaaaaaataa tttaaatatg
     5461 atatatagtc atttatttag tgatttcatt ctaaaataaa gggagaaatg tctatgctat
     5521 acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc cattggcgat gaagaaatga
     5581 cgatcaagga aagagtgagc tttccgacaa cgacacctga ggaaacaatg cctttagtca
     5641 ttgacttctt caaacaatac caagcagatt tagcagggat tgggattggc tcatttgggc
     5701 ctatcgatat ccatcgcgat tccgccactt atgggtacat tacctcgacc ccgaaattgg
     5761 catggcaaaa ttttgatttc atcggtacca tgaaaaaaga atttccgatc ccgatttctt
     5821 ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt cttcggcagt ggcaaaggat
     5881 tgagcagtgt cgtttactat acgatcggta cgggtgttgg cggcggtgcc ttacaagaag
     5941 ggcgctttat cgaagggttt agtcatccag aaatggggca tatgctcgtc gtccctcatc
     6001 caaaagatga ctttgctggc agctgtccat ttcatggcaa ctgtttagaa gggatggccg
     6061 ctggacccgc catcgaaaac cgcttaggga aaaaaggaca agaggttgca gaagatgatc
     6121 cttattggga aatcgaagcc tcctatattg ctcaatgtgc ctacaataca accttgatgt
     6181 tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa
     6241 acgtccacga cgcatttgca aaattggtca atgggtatgt cgaaacacct gagttaagca
     6301 aatatatcgt gaccccagca ttagaagaca acgctggaac gctcggttgt ttggcattgg
     6361 ctcgagaagc ggtcttacat tcataaacga aaaaaggctc ttcgacattt agtgttggta
     6421 gagaaagata caactgaaaa tttagtcata accagttagg cagagtgctt aactggtttt
     6481 tgttttactt ggaagatcaa gccttgaatg agataaattc ttgctcgaaa gttatggaaa
     6541 tttcgatagc cgtaggccac ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc
     6601 ggatattttt ttggaccttt ttaacaaata ggttctgttg caaagtttta aatctactat
     6661 cagataaggt agaataatag aaaaagatag caggaggaat gacgatgagt cattttaaag
     6721 gaaagcaatt tca
//
LOCUS       DAZKPE010000109         6650 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000109 DAZKPE010000000
VERSION     DAZKPE010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.111"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            107..1114
                     /locus_tag="ACG930_002711"
     CDS             107..1114
                     /locus_tag="ACG930_002711"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFQ0519826.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1126..2130
                     /gene="neuB"
                     /locus_tag="ACG930_002712"
     CDS             1126..2130
                     /gene="neuB"
                     /locus_tag="ACG930_002712"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFQ0519827.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2127..3275
                     /gene="neuC"
                     /locus_tag="ACG930_002713"
     CDS             2127..3275
                     /gene="neuC"
                     /locus_tag="ACG930_002713"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFQ0519828.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3248..3925
                     /locus_tag="ACG930_002714"
     CDS             3248..3925
                     /locus_tag="ACG930_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFQ0519829.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3876..5057
                     /locus_tag="ACG930_002715"
     CDS             3876..5057
                     /locus_tag="ACG930_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFQ0519830.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            5070..6047
                     /locus_tag="ACG930_002716"
     CDS             5070..6047
                     /locus_tag="ACG930_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0519831.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            6047..>6650
                     /locus_tag="ACG930_002717"
     CDS             6047..>6650
                     /locus_tag="ACG930_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFQ0519832.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEIN"
BASE COUNT         2476 a          830 c         1266 g         2078 t
ORIGIN      
        1 gattcgttac gttttgacat cattattgat aattagttta gttatatatt ttttaaagat
       61 taagaatcga attatagatg actataattc ataggaggag atataagtgt ttaaaggaaa
      121 aacaatatta gtaactggcg gaactggttc cattggaagt gaaattgttc gtcagctttt
      181 aaaatatgaa ccaaaagcta tcagaattta tagtagaggt gaagaaaaac aattttatat
      241 gcaacaagag ctctcaaatc acactaattt gagattttta attggtgata tcagagactc
      301 tcaaaggatt gattatgcat gtcgtgatgt ggatattatt tttcatgctg ccgcaatgaa
      361 acacgttcca gcaagtgaat ataatcctat ggaagctgta aaaacaaatg tgatgggaac
      421 tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa cattttgtag gtatcagtac
      481 agataaagta gtgagtccta ctaacaccat gggtgcgaca aagttattga gtgaaaaatt
      541 aataatagct gccaatcagt ataaaggaaa aacagaaaca atattttctt gtgtaaggtt
      601 tggaaatgtc atggggtcaa gtggatctgt tattcctctt tttagtaaac aaataaaaaa
      661 caataaagat attactttga cagatgttga tatgacacga tttatgatgt caataccgga
      721 tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa tttggagaaa catatgtctt
      781 aaaaatgccg gcaatcaata ttttaacttt agctcaatca ttaataaaaa tatataatga
      841 tacacatgat gaaaaatata gaggtgaaat aaaagttgta ggtatcaggc caggagaaaa
      901 attatatgaa gagctaatga ctacagacga aattgaacgc tcatatgaaa atgataaaat
      961 gtatatcatt ccaccacact atcatgctac tgacgaactg tacaaagatt atgaaaaaat
     1021 taaaatcact gcatactctt cagatgcaac agaattaatg agtggacagg aatttattag
     1081 aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt ttatgatgaa atcagaagta
     1141 tatgtaattg cagaaattgg tgtaaaccat aatggaagtc tagatttagc tttagaaagt
     1201 attgataaag ctaaagaatg tggagctaac gcggttaaat ttcaaacatt taaaacgaat
     1261 aagctagttt ccaaaaaggc tccaatggca aaatatcaga aggataatct taaagaggac
     1321 agttctcaat ttgaaatgct aaaaaaatta gaattatctc aatctgattt tattagaata
     1381 aaagattatt gtatacaaaa taaaattgat tttttgtcta ctccttttga tgaagaaagt
     1441 gcagactttc taaaacaaat tggtgtacaa ggatttaaaa ttggctcagg agatttaaca
     1501 aatttacctt ttcttagaaa aatagatatg tatgggttgc cagttttatt atctacaggt
     1561 atggctgata ttcatgaggt cagtgaggct gtagattgtt tcatagatag tccagttact
     1621 attttacatt gtacttcaaa ttatccggct agttctgaag atattaattt attggcgatt
     1681 aacacattaa aagaaatgtt cgggataccc gttgggtact ccgatcattc attgggatat
     1741 gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa ttgagaaaca ttttaccttg
     1801 gataaggaac tacctggtcc agatcataaa gcttctttag atcctcagga atttgcagat
     1861 tttgtaaagc atattagaaa cactgaaata tttttaggtg atggtgttaa gcgagcaatg
     1921 ccttctgaac ttagtacaaa agaagtatca agaaaaagcc tagtggtcac tgagaattta
     1981 aatgtgggag atattcttac agagaaatct cttacaataa aacgtcctgg aaatggaata
     2041 gctcctaagt ttttatatca atatattggc aaaaaagtta aaagaccaat aagtgcagat
     2101 agtgttctgc ttgaggaaga tgttgaatga aaaaaatact tatagtaagt ggaacacgag
     2161 ctgattatgg aatatataaa cctgttgctg agaatttact acaagataat tgggatgtat
     2221 catttgttgt ttctggaatg catttatccc ataaatatgg atttactaaa gaattgatct
     2281 tagctgacgg atttagaatt agtggagaag ttcaaagttt gtttttagag aacaataagg
     2341 gaaacatggc tcggtctgtg gcattagaga taaatggttt cacaaatata tttgaacaaa
     2401 ctagccctga ttttgtatta ttactagggg atagaggaga aatgttggca gctgcgatag
     2461 cttgtttgta tcttggaatc aaaacagcac atattcacgg aggcgaagtg tctggtactg
     2521 tagatgaatc aataagacat gccataacga aaatagcatc tgttcatttt gctgctacgg
     2581 aaaaaagcaa agagcgttta ataaaaatgg gggaagattc ttggagagtt tttcccgtcg
     2641 gagctcctag aatagatact attttaaata atagattacc tagttttaga gatataaaag
     2701 aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt gcaagtattt catccagttg
     2761 taaccgaact agaaaatata gaaaaacaaa ttttagcttt gatcaattca atggaacaac
     2821 aatctcaacc aattatttgc attttaccta atagtgatgc tggtagcgaa attatcagaa
     2881 aaatgtacca gaaatattta aaaacggata ttatttatat tacgaattta gagccggagg
     2941 aatacctgac tatattaaaa gagtgcaaat ttatgatcgg aaattcttct tctgggataa
     3001 ttgaagctgc atcattcaaa ataccagtaa taaatttagg aaccagacaa aatggacgag
     3061 aacaatctaa aaatattata aatgcaaatc taaatgaaaa tgaaattgaa actgctttga
     3121 ataaaataca agatcctcag tttataaaaa gcttgaaaaa tgttaagaac atctacggtg
     3181 acggcaacag ttctagaaga ataacaaaaa cattgaatca aatattgaat gatggggaag
     3241 atattaagtg gattcaaaaa caaatagctt attaaaatat actagtgatc catacattat
     3301 tattggggct ggcggacacg caaaagtcat tattgaaacc ttaagattag aaaataagtt
     3361 aatatatgga ttttttgatg ataagcaaaa taaaatgcaa gatctgaaat atcttgggaa
     3421 aataaacgaa ttgaatagct gggcggatag caaaaaaaaa atctataaat ttattgtagc
     3481 tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa ttgaatatgc caagtgagca
     3541 atatggaata gctgttcatc caagtgctat agtggcaaaa gaaatttcaa ttggttatgg
     3601 aactgttatt tttgcgaatg ctgtaattaa cccagatgct gtaattggag agcatgctat
     3661 aataaacaca ggtagcattg ttgagcatga ttgtagaatt aataactatg ttcatttatc
     3721 tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta ggaactcaaa taggaattgg
     3781 ttctcaatgt atccagatga agaaaattgg atcttggtgt atgataggcg cagggagcac
     3841 tattgttaag gatattccct cacattcctt agcttatggc aatccagcta aaattaagaa
     3901 agaaggaatt aattttgaat tctagaattt tattatcaag tcctcatatg ggaggaacag
     3961 aagaaaaata tgttgctaag gcttttaaag ataattggat agcgccatta ggtgaaaatg
     4021 tggataaatt tgaagaaagt attacaaaat atactggttc taagggcgga gcttctgcgt
     4081 taagttcagg tacagctgcc atacatcttg ccttaagact gcttaatgtt ggaaaaaacg
     4141 atattgtctt tgctccttca tttactttta tagctacagt aaatcctatt ttatatcaag
     4201 gggctgtacc agtgttcatt gactcagaac ctaatacatg gaatatgagc cctgttgcac
     4261 tagagagcgc attagaagaa gctgaaagaa acaaccaatt acctaaggca atcatcgtag
     4321 tgaatttata tggtcaaatg gctgattatg aacgaatttt agctattgca aaccaattta
     4381 atgttccagt gatagaagat gcagcggaat cgttaggttc tacttataag ggaatttcgt
     4441 caggcttatt tgggacaatt gggatctatt catttaacgg taataagatc atcacaacct
     4501 caggtggagg agctctagtg tctagtgata aaaaatatgt tgagcattca agatttttag
     4561 caacacaagc aagagatcaa gcaccgtatt atcaacatag cgaaataggt tataattacc
     4621 gtctaagcaa tatttctgcc ggtatcggac gtggacaaat ggaagtattg aatgatagag
     4681 tagctaaacg aagagaaatt ttcaatcgat ataaggaagc tttttctgga attgatagaa
     4741 ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg ttggttgtct actttaacga
     4801 tcaatgatta taattctatt gatcaagtag ttaacgtaat aaataaacta aatgaaaaaa
     4861 acattgaaac aagagctttg tggaaaccac tacatttgca accagtattt caaggggtaa
     4921 aaatgtatta ccatgataat aatcttagtg tgtcagaaaa gttatttaat agcggcttat
     4981 gcttaccttc tggaagtaat atgacagata gtgaacaaga atttgttatt gatgagttta
     5041 aaaaaatatt caagtaggtg tgatatttta tgaacatagg aattattggt ttaggttcca
     5101 tggggaaaag aagacttaga ctcattcaag aacactttaa tgatatttta ctatgtggtg
     5161 ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga atttggaata ccaacttata
     5221 atagtctaac agaggcaaaa aatttgtttg aaataaattc agtttttgtt tgtacatccc
     5281 ctataaccca tgaatttatt ataaaagagg ctttaaattt agattgtaat atctttacgg
     5341 aaatcaattt attaaatgaa tattatgatg aaataatcga agtagctaaa aagaaagata
     5401 gattacttta tctatcttct acatttttga agagaaaaga aattcaatat attaagtcta
     5461 aagtgacgca taataaaaaa atttcttatc aataccatgt aggacagtat ttacccgact
     5521 ggcatccttg ggaagattat cgcaattttt ttgtttcaaa caaaaaaact aatgggtgta
     5581 gagaaatatt cgctattgaa ttaccttgga ttatagatac atttgggaaa gttaaatcgt
     5641 ttactgtaat gacccagaaa ttatccaatc ttgatattga ttattcggac agtttcactc
     5701 ttattattga gcatgaaact ggtatagttg gaactttaag tgtagatgtt gtttcaagag
     5761 tagctaaaag aaatttaact ataattggtg aaaagatttt aatagaatgg gaaggtaacc
     5821 cggattctct attttcatgg aatgaagaaa cttctagtat gacagatatt caattgtacg
     5881 atgaggttat gcatgataat aattattcac atactattat tgaagatgca tatttagagg
     5941 agattaaaga atttttcacg cttttggaaa agaaaatgga accccaatat acttttgaaa
     6001 aagataagta tattattaac ttaattaacg acattgaggt aaattaatga tgaaagtaat
     6061 tttttttggg ttagggtcaa ttggaaagag acatctaaaa aatctaataa gctatggaaa
     6121 aaagaattct attaattttg atataacagc ttatagtagc agtggaaaaa aagagtttga
     6181 agaaataacg tatattcaaa atagagacga tttggataca cattatgata tagcttttat
     6241 tacaaatccg acttttaagc atctggaaac actaaatgta attgttgaaa aagttgatta
     6301 catattttta gaaaaacctg ctttttctga gagtattgat cttactcaat ataattatga
     6361 ttacaaaaat atttatgttg ctgctccact gaggtataaa aatatcatgg aagttgttcg
     6421 taatagtatt caaagtaaaa aagtatattc tgtaagagct atttgttcta cttatcttcc
     6481 tgattggaga aaaggtactg attatagaaa taattattct gcctttaaat ctatgggggg
     6541 aggagtagaa ttagactgta tacatgaatt ggattatatt ataaacctat ttggtttccc
     6601 taaatcagta aaaaaacagt ttggtaaata ttcgaatctt gaaattaaca
//
LOCUS       DAZKPE010000110         6570 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000110 DAZKPE010000000
VERSION     DAZKPE010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.112"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            250..779
                     /locus_tag="ACG930_002718"
                     /pseudo
     CDS             250..779
                     /locus_tag="ACG930_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(951..1184)
                     /locus_tag="ACG930_002719"
     CDS             complement(951..1184)
                     /locus_tag="ACG930_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519833.1"
                     /translation="MSKELKKLVADLQGNMDVVGEFMDSPQSVLDKYNVQGKERTVML
                     AKDSEGLNKLGFSSQLVEGALSGAHSQRCHAPI"
     gene            complement(1236..2309)
                     /locus_tag="ACG930_002720"
     CDS             complement(1236..2309)
                     /locus_tag="ACG930_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFQ0519834.1"
                     /translation="MIVPIGIKKGKLIYKEKNQVNHFYVPNCKASGFLNNVRSIDYNT
                     LLHDTYKNLSLTVTNDKGGNIVFVNQEKLNIPVHFTVKNCYFLDNKTLILLCSSTLNS
                     SMLVYYSIPERELNYLKMTSQLTFPLSFFEHQIIGEKKIPCLTHINRSDDTVLICLHG
                     GPKYHYNHEYLDLIFDFYHNFNNICLVNFPGSTGYSQKYENELIGNGGVVDVEAVKSV
                     VSYYDSQGFKIKIYGESYGAYIAICLSQFINFSIARIVSVSGFTNLFYMYLCSDSRNL
                     IEKYFSDYRKFSPEKNLAMKELLPIRFLHGSEDKTCPIAQINYFVKKYEGMHLTVLDG
                     FSHYEVDIKKEKIRNKRIVRLLK"
     gene            complement(2459..3265)
                     /locus_tag="ACG930_002721"
     CDS             complement(2459..3265)
                     /locus_tag="ACG930_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519835.1"
                     /translation="MMPSQFREQHYLGIKGLKIIVKNELNAFLRNKGLIISQLVQPIL
                     YYIFIVLGINSFVTNIAYEGKTISYADYALTGILGILIISQMTQTIYRITIDKRYGLL
                     ALKRQSGVSPFYYIIGMSMYPTIGICIQSSVLYIIATLFGSSIGLISYLAGIIVVIIV
                     LYFWTSIAALITMKINDYQRRDSIISFIITPLGFTAPAFYLITNVPTFIKVIGYFNPL
                     TYQLYAIRSIVFATPANSLLIIVLVFLATLIMISISSFAVSKMSLVLTER"
     gene            complement(3267..4187)
                     /locus_tag="ACG930_002722"
     CDS             complement(3267..4187)
                     /locus_tag="ACG930_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519836.1"
                     /translation="MKKNVLDIKDLSLKYGKKFAIKDINLSIFTGEIVALVGHNGAGK
                     SSLFNIIAGIQTPTTGSVEFDQDFIEKRLFATIGFSPQTQVMDWYTNVWDNVYLGSQL
                     AGIDAKTGKLLTEKALDLLSISDLKNKPVDALSGGQQQRVQIARSIVHQPDFYLLDEP
                     TTGLDAETSNRLLSFLKKEAAKGKSVFVSSHDLHLLEEFCDNLVLIDKGRVLYAGDLK
                     NFLIENAPKKSYQITTDRSIHEEIIHKLNEKGIAVTGLDNFQYRFILNQESDLTQLFM
                     DTKEFFRIDEIVKETMSLRDLYIHYREGGL"
     gene            4250..4540
                     /locus_tag="ACG930_002723"
     CDS             4250..4540
                     /locus_tag="ACG930_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519837.1"
                     /translation="MAERTIDQKIQNVLKKFIDSYKDNRSLTPQTSYLFYDFIILSYH
                     NKRKNRYSISTLSEILLAEGIEANLLINIYAHSLYVLALNDGKQIYDKGFLI"
     gene            4537..5844
                     /locus_tag="ACG930_002724"
     CDS             4537..5844
                     /locus_tag="ACG930_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HFQ0519838.1"
                     /translation="MNYYDRVKRQHGIYFNLLSKYNLHPLKKDHWIYAYKQMYNKKKQ
                     GFKIHLSANTNNAINIAKKFLNYNETKQLDFKIVSTLAKFDIQNTGALGYSQIGKLIT
                     IYPNDDDEFLYTLNELELIFKSDLSPEIPSDFRYMLSSVVNYRYGEIVVDPNFNDLRD
                     KTIPNDIIIPVDDYYIPRLKEIPKHLLLLKVIKKTGKGGTYQCLDLKRNELVLLKQGI
                     HQGDLTIDNVDTINLLSLEKRSLLKLNKENQFPTFIDDFYLENSYFLEINYLNKETLY
                     QFMKKEPLSPEKIKSIILKIISVVKLLHEKYNIIHRDISFDNVLIDEHQEISVIDFEF
                     SYDLKQWNPPSIIMGTPGFYNANRLNIDQYTDVYSIISLLYFMDNFDLYCNYKNDHNK
                     LTLQRNSIDKGTSSFYFIYLQAQYHSARYSLDMLEHDLRTLSV"
     gene            5915..6091
                     /locus_tag="ACG930_002725"
     CDS             5915..6091
                     /locus_tag="ACG930_002725"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0519839.1"
                     /translation="MDMNAPYFELVKAVFPNAKIVTDRFQIVQKITRALNQLRIKTMN
                     SFQKTEPTKYRRLR"
     gene            6199..6552
                     /locus_tag="ACG930_002726"
     CDS             6199..6552
                     /locus_tag="ACG930_002726"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0519840.1"
                     /translation="MSYDEQLTRAYETCQLLLNHFKHKDCQSFFDTINSLDQRLTQWF
                     CKKLTFLNKYKLGIQYALKTKYSNGALEGTNNKIKVIKRVAYGYRNFHNFRARLYLIQ
                     GLIIQVKQKPVKHFA"
BASE COUNT         2362 a         1106 c          891 g         2211 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtatat aaaagaacaa cttcaaaaga
       61 ataattaaat ttttcaactt gcggatacta aaatagttga agtaatttat tgaaattagg
      121 ttgattgagt atttgttcat agactgtcat tcgcttggta catcttttac tttgctctcc
      181 tcctccaccc tcgtcagttg ttttcgagtt tcatagattg atcaaaatga acaaaggcaa
      241 cttgaagaaa tgaagaagtt cggcgcagaa aaaatattta ttgagaaaca atctggagca
      301 acgattactc atcgaccaat tttccaagaa gctttagaat ttgtctgaga acaagatatt
      361 tttatcgtgg aagccatcga tcgacttgga agaaattatg acgagatcat tgaatcggtt
      421 aattatctaa aaagaaaaaa tgtacaactt atcatcacta gtttaccaat catggctgaa
      481 gcaatcctct cttggataag ttcatcaagg atttaatcat tcagatcctg gccatgattg
      541 ccgaacagga acgtacagaa tctaaacgac gccaggcaca aggaattaag attgcaaaag
      601 caaatggtgt ttataaagga cgtcctaagt tatacagcgc agacacaaaa gatccccaac
      661 gtcgccttgt ttataaaagc atcgttgagg atctaaatca gggtattgct atttcaaaaa
      721 ctgcaaaaaa ttataacatc actagacaaa cagtttatag aataaaaaac gatttgtaag
      781 tatggtaagg aaacagctct ctttattctc agatatctaa aactacaata aattaaactt
      841 caactttgca aataaatcag actatttaag tataattgat tgacttaaca atgctattag
      901 cacaataata tccctctaca taaataaagt agagggatat ggaaatattt ttatattggt
      961 gcatgacatc tttgactgtg agcaccagat aaagctcctt caactaactg actcgaaaac
     1021 cctagtttat tcaaaccttc gctatctttt gccaacatca cagttctttc tttaccttgt
     1081 acattgtatt tatccaagac actttgagga ctatccataa attcaccgac aacatccata
     1141 tttccctgta aatctgcaac cagttttttc aattctttag acataatact gcacctccgt
     1201 aaagtttata attatatgat aacattcatc agtaattact tcaataatct gactattctt
     1261 ttatttctga ttttttcttt ttttatatct acttcataat gagaaaaacc atctagtact
     1321 gtcaaatgca ttccttcgta tttttttaca aaatagttaa tttgtgcaat cggacaagtt
     1381 ttatcttcac ttccatgaag aaatcttata ggtaataatt ctttcattgc cagatttttt
     1441 tctggagaaa atttcctata atcagaaaaa tacttttcaa taaggtttct cgaatctgaa
     1501 caaagataca tataaaataa atttgtaaat ccactaacag agactattct tgctatacta
     1561 aaattaataa attgagagag acagattgcg atatacgctc cataactctc accatatatt
     1621 tttattttaa atccttgaga atcataatag ctaacgacag attttacagc ttcaacatca
     1681 acaacacctc cgttacctat taactcattt tcatattttt gggaatatcc tgtacttcca
     1741 ggaaaattca ccaaacaaat attattgaaa ttatgataga aatcaaagat taaatctaag
     1801 tattcatgat tatagtgata tttaggtcct ccatgcaaac atatcagaac tgtatcatca
     1861 cttctattaa tgtgagttaa acaaggaatt tttttttcac caattatttg atgttcaaaa
     1921 aaagaaagag ggaaagtaag ttgactagtc atctttaaat aatttaattc tctttcagga
     1981 atactgtaat aaactagcat tgagctattc aaagttgaac tacataaaag aatcaatgtt
     2041 ttgttatcaa gaaaataaca attttttaca gtaaaatgta ctggaatatt taatttttct
     2101 tggtttacaa atacaatatt gcctccttta tcattcgtaa cagttaaact caaattttta
     2161 taagtatcat gcaacagagt attataatca attgatctga cgttatttaa gaaaccagag
     2221 gctttacaat taggcacata aaaatgattc acttgatttt tttctttata gataagcttt
     2281 ccttttttta tacctattgg cactatcata aaagatcttt cgcatatcat atctttcttt
     2341 tcaaatggat acagcgaata ataaagtcta taattacctg ttttacttag catacttgca
     2401 attatacatt ttcgatcatt agtaaaaaaa atgcttagga ttctcactca gtcaccttct
     2461 atcgttctgt cagcactaaa ctcatcttgg aaacagcaaa tgacgaaata cttatcataa
     2521 tcaatgtggc taaaaatact aaaacgatga ttaataaact atttgctggt gtagcaaata
     2581 ctatagacct tattgcatat agttgataag ttaacggatt aaagtaacca ataactttaa
     2641 taaatgtagg gacatttgta attaaataaa atgcaggagc tgtaaaccct aatggagtaa
     2701 taataaacga aataattgaa tctcttcgct gataatcatt aattttcatc gtaatcaacg
     2761 cagctatgga tgtccaaaaa tacaagacaa ttatcacaac tattatccct gccaaataac
     2821 tgattaaacc aattgagctt ccaaacaaag tagctataat ataaagtaca ctagactgaa
     2881 tacatatgcc tatagtagga tacatactca ttcctataat gtaataaaat ggtgaaactc
     2941 cactttgacg tttcaaagct aatagaccat atcttttatc tatagtaatt cgataaattg
     3001 tttgagtcat ttgtgaaata atcaatattc ccaaaatccc agttaaagca taatcggcat
     3061 aagaaattgt tttcccctca taggcaatat ttgtgacaaa actattgata cctaagacaa
     3121 taaaaatata gtacaagatc ggttgaacca attgtgatat gatcaatcct ttgtttctaa
     3181 gaaacgcatt tagctcattt tttacaatga tttttaatcc ctttattcct aaataatgtt
     3241 gctccctaaa ttgacttggc atcattttaa agaccccctt ctctataatg aatgtataag
     3301 tctcttaatg acatagtttc cttaacaatt tcatctattc taaagaattc ttttgtatcc
     3361 ataaacaatt gtgttaaatc actttcctga tttaatataa atctatactg aaagttgtct
     3421 aatcctgtca cagcaatacc tttttcattt aacttatgaa taatttcttc atggattgat
     3481 ctatcagtag taatctggta acttttttta ggcgcgtttt cgatcaagaa attttttaga
     3541 tcccccgcgt ataaaaccct tcctttatct atcaaaacta aattatcaca aaattcttct
     3601 aataaatgta agtcatgtga cgacacaaaa actgatttcc ctttagctgc ttcttttttt
     3661 aaaaatgaca acaaccgatt agatgtttct gcatctagtc ctgttgttgg ctcatctaac
     3721 aaatagaagt caggctggtg aacaatggag cgcgcaattt gaacacgttg ttgctgtccc
     3781 ccagatagtg catctacagg tttatttttt aaatccgata tacttaataa atctaaggct
     3841 ttttcggtca ataattttcc tgtttttgca tctattcctg ctaattgact gcctaagtaa
     3901 acgttatccc acacatttgt gtaccaatcc atcacctgag tctgcggtga aaaacctata
     3961 gttgcaaata atcgtttttc tataaaatcc tgatcaaact ctactgaacc cgtcgtcgga
     4021 gtttgaatcc cagcaataat attgaataag cttgatttac ctgctccatt atgcccaact
     4081 aatgctacta tttcaccggt aaatatggaa agattaatgt cttttatcgc aaattttttt
     4141 ccatatttaa gacttaaatc ttttatatct aatacatttt ttttcattac taaactcctt
     4201 ttctaaggta taattaatta aatcttactt aaaagagagg gattctaata tggctgaacg
     4261 aaccatcgat cagaaaattc agaatgtttt aaaaaaattt attgattcct ataaggataa
     4321 tcgaagtctc acaccccaaa cctcctattt attttatgat tttataattc tatcctacca
     4381 taataaaaga aaaaatcgtt acagtatttc tacgttgtca gaaatattat tagcggaagg
     4441 tattgaagca aatttattaa taaatatata cgctcattcc ctttatgtac tagcattgaa
     4501 cgatggcaag cagatatatg ataaaggatt tttaatatga actactatga tcgagttaag
     4561 aggcaacatg gtatctattt taatttatta tctaaatata acttacatcc cctaaaaaaa
     4621 gatcactgga tttatgcata caaacaaatg tataacaaaa aaaaacaggg atttaaaatt
     4681 catttaagtg ctaatactaa taatgccatt aatatagcta aaaaattttt aaactataat
     4741 gaaacaaaac aactagactt taaaatcgtt tctactctag caaaatttga catacaaaat
     4801 actggggcat taggatattc tcaaatagga aagttaatca ctatttatcc aaacgatgat
     4861 gatgaatttc tttatacact taatgagcta gaactgattt tcaaatcaga cttatctcct
     4921 gaaatccctt cagattttag atatatgtta agttctgtgg ttaattatag atatggagaa
     4981 atagttgtag accctaattt caatgacctt agagataaaa ctattccgaa cgatataatt
     5041 atacctgtgg acgattacta tattcccaga ctaaaagaaa ttcctaaaca tttattacta
     5101 ttaaaagtta taaagaaaac tggtaaaggt ggaacatatc aatgccttga tttaaaaaga
     5161 aatgagctag tactattaaa acaaggtata catcaaggtg atttaacaat cgataatgtg
     5221 gatactatta atcttttatc tttagaaaag aggagcctct taaaactaaa taaagaaaat
     5281 caatttccaa cgtttattga cgatttttat ttagaaaact cttatttctt ggaaataaat
     5341 tatctaaata aagagactct atatcaattt atgaaaaaag aaccgttgtc tcctgaaaaa
     5401 ataaaatcaa ttattttaaa aattatttca gtagttaaat tgctccatga aaaatataat
     5461 attattcata gggatatttc attcgataat gttttaattg atgaacatca agaaatttct
     5521 gtgattgatt ttgaattttc ctatgatttg aaacaatgga atccaccttc tattattatg
     5581 ggtactcctg gattttataa cgcaaaccga ttaaatatag accaatatac agatgtttac
     5641 agcattatca gtctattata ttttatggat aatttcgatc tatattgtaa ttataaaaat
     5701 gaccacaata aattaacttt acaaagaaat tcaatagata aaggtactag ttctttttat
     5761 tttatctatt tacaagctca gtatcattcc gctaggtatt cactagatat gcttgaacat
     5821 gatttaagga ccctaagcgt ttaaattgtt atagttaaaa ccatatttcc ttaatttcac
     5881 tcgaaaagca cgagcgaacg taaattacgt cgtgatggat atgaatgccc cttattttga
     5941 acttgtaaag gcggtcttcc caaacgccaa aatcgtgacc gatcgctttc aaattgtcca
     6001 aaaaatcact cgtgcattaa atcagttgcg aattaaaaca atgaacagct ttcaaaaaac
     6061 ggaaccgaca aagtatcgac gattgaggtg attctggaaa ttactcctta agcatgctta
     6121 tgatctggat agttccaatt atcagtatga tcgatccttt cgtagaccaa tgagcaaaaa
     6181 gcgatcgtcg atgaactttt gagttatgat gagcaattaa caagggctta cgagacttgt
     6241 caacttctcc tcaatcactt taaacacaag gattgccaaa gctttttcga tacgatcaac
     6301 agcttagatc aacgcctgac acaatggttt tgtaagaagc taacgttttt aaataaatac
     6361 aaattaggga ttcaatatgc tttaaaaacc aagtatagta atggtgcatt agaaggaaca
     6421 aataacaaga taaaagtgat aaagcgagta gcctatggct atcgaaattt ccataacttt
     6481 cgagcaagac tttatctcat tcaaggtttg atcatccaag taaaacaaaa accagttaaa
     6541 cactttgcct aactggttat gactaaattt
//
LOCUS       DAZKPE010000111         6390 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000111 DAZKPE010000000
VERSION     DAZKPE010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.113"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            330..1175
                     /locus_tag="ACG930_002727"
     CDS             330..1175
                     /locus_tag="ACG930_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFQ0519841.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ACG930_002728"
     CDS             1456..2676
                     /locus_tag="ACG930_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFQ0519842.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ACG930_002729"
     CDS             2673..5393
                     /locus_tag="ACG930_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0519843.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ACG930_002730"
     CDS             5377..6321
                     /locus_tag="ACG930_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0519844.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1793 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt
//
LOCUS       DAZKPE010000112         6347 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000112 DAZKPE010000000
VERSION     DAZKPE010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.114"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG930_002731"
     CDS             complement(99..1229)
                     /locus_tag="ACG930_002731"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFQ0519845.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG930_002732"
     CDS             complement(1878..3080)
                     /locus_tag="ACG930_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0519846.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG930_002733"
     CDS             complement(3140..3343)
                     /locus_tag="ACG930_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFQ0519847.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACG930_002734"
     CDS             complement(3485..4552)
                     /locus_tag="ACG930_002734"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0519848.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG930_002735"
     CDS             complement(4610..4717)
                     /locus_tag="ACG930_002735"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519849.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG930_002736"
     CDS             4880..5692
                     /locus_tag="ACG930_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519850.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACG930_002737"
     CDS             complement(6066..6257)
                     /locus_tag="ACG930_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519851.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         1895 a         1301 c         1001 g         2150 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatac
//
LOCUS       DAZKPE010000113         6173 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000113 DAZKPE010000000
VERSION     DAZKPE010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.115"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACG930_002738"
     CDS             725..811
                     /locus_tag="ACG930_002738"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFQ0519852.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACG930_002739"
     CDS             complement(932..1621)
                     /locus_tag="ACG930_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519853.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACG930_002740"
     CDS             complement(1628..1906)
                     /locus_tag="ACG930_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519854.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACG930_002741"
     CDS             complement(1866..2780)
                     /locus_tag="ACG930_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFQ0519855.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACG930_002742"
     CDS             complement(2762..3142)
                     /locus_tag="ACG930_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFQ0519856.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACG930_002743"
     CDS             complement(3592..3879)
                     /locus_tag="ACG930_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFQ0519857.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACG930_002744"
     CDS             complement(3899..4123)
                     /locus_tag="ACG930_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFQ0519858.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACG930_002745"
     CDS             complement(4578..4748)
                     /locus_tag="ACG930_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519859.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACG930_002746"
     CDS             complement(4763..5296)
                     /locus_tag="ACG930_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFQ0519860.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACG930_002747"
     CDS             complement(5317..>6173)
                     /locus_tag="ACG930_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFQ0519861.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAZKPE010000114         6035 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000114 DAZKPE010000000
VERSION     DAZKPE010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.116"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     regulatory      complement(21..87)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(129..776)
                     /locus_tag="ACG930_002748"
     CDS             complement(129..776)
                     /locus_tag="ACG930_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFQ0519862.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1184..1687)
                     /locus_tag="ACG930_002749"
     CDS             complement(1184..1687)
                     /locus_tag="ACG930_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFQ0519863.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1810..2574)
                     /locus_tag="ACG930_002750"
     CDS             complement(1810..2574)
                     /locus_tag="ACG930_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFQ0519864.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2682..2957
                     /locus_tag="ACG930_002751"
     CDS             2682..2957
                     /locus_tag="ACG930_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFQ0519865.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(3158..3505)
                     /locus_tag="ACG930_002752"
     CDS             complement(3158..3505)
                     /locus_tag="ACG930_002752"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519866.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            3673..4602
                     /gene="yidC"
                     /locus_tag="ACG930_002753"
     CDS             3673..4602
                     /gene="yidC"
                     /locus_tag="ACG930_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFQ0519867.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            4723..6035
                     /locus_tag="ACG930_002754"
                     /pseudo
     CDS             4723..6035
                     /locus_tag="ACG930_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320902.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1873 a         1155 c         1110 g         1897 t
ORIGIN      
        1 aagaaagggg ctgtccccag actttagtag gcgtcattag ctatctttcg ttagcattta
       61 aaggcgaaca ccatcaccta ttcacttcca ttaaaagata gcatattttt ctgtaaaaaa
      121 caataaaatt atcgttcttt ctttacacgt tcagcaaatt catagaaagg agccaatttc
      181 gttaactgtt gattacattg gtcactatca tgacaaatat aattcccctt tttcgtatac
      241 gtgccatcag aacctgcttt cgttgtagaa agaaaaagcg aaacattcga tgttttctga
      301 cagattgcac agattccctt atttatcgtt ggtgataaag taccgctaat cccttttaat
      361 ttttcatctt cgtaatagac catgaatttt ttctgcgtac ctggatcatt ccagccgatg
      421 tacgtatgtt cttgcaagtc gatttcattc caagctggtt gtttgagttt tttcactttt
      481 cggaataatt tctcgatttg tggtttgcta ggctgcataa acggctgaac gatttgcttc
      541 agctcctcca atgctctttc tgcttgcgct tttgtcagtt ttacgtctaa aactgtcgtt
      601 aaaaatgtat cgatttctgg cagttcgtga tctaatatgt ctcgaatctt ttcagctgct
      661 agtgcctgaa ctgtttgtac cgtttttgga tcattgacag atgagtacgc atttaataac
      721 tgttctactt ctcttattat aaaaaaatat tggtatggtt ttattgtttg ttccatgatt
      781 ttaaagtcct ttcttctaac caaagtgcat actttgtaga aaaaagtgat cttctgcaaa
      841 gtatgtgtta cctgaagatc ctggactctt ttaaataaga tacgttttgc atcttatcat
      901 cacccccttt aatgcttatt attctatgta catgattcat tcgataaata aaagtaaacc
      961 gtatcttgaa cagatagtca actgcaaaca gaaaaaagga ctgtgacaaa agtcgtgtca
     1021 aagtcccttg tttcgaatga atggtgttca aaagcttgca tctgcagtaa taagccgaaa
     1081 cttcacaaaa atttgagaag taattttcgt aaattccttc ttatttcttg aagctgacca
     1141 cttctgtcac aacctcaata tggtctatta ttggttttac ctgttaaatc gaggattctt
     1201 tcccaaagta acgttgccat ctcttacgca tacttgcaga catgggctga gccgcttctt
     1261 tgactgcgca gtatttgtcc acgaatgtca caatatatcc ttctttatac ttaggcggtg
     1321 cgatcgttgc accccacatg tgcttcaaaa tgatatctcg ctcaagatcc gacaaatcgg
     1381 tgattttttc tgcattcttt acagcaattc ttggatggat atacgcatgt gtcccctcgt
     1441 caaatttcgt cgtacgccaa tcatagtaga acagatcatg caaaagtcca gcacgcgctg
     1501 ttgctttagc attgccaccc catttttttg cgagcagata actatagtaa gaaacactga
     1561 tggaatgctc caaacgagtg gaatgaacat gctgtgtgta attcgctaat tttttcactg
     1621 cttctgtttc taaaagatct tgtacataag acatatattc ttcgtcttca cgccattttt
     1681 ctgtcataat tatcgatctg ccaccttttt gaatttcatt ttcttctgaa attgatctaa
     1741 gtataccacc agtgttcgga ttattctagt cgctctagat aaaatagcta aagcttaata
     1801 gttccttaat cataaagaaa aatgataaag aacgatccct gctgcgactc cgacattcaa
     1861 tgattccgca tttcctttca ttgggatata tacgttctga tcagtcaaag acaagatttc
     1921 ctgactgact ccctgacctt cgtttcccat gattatagcg aaatcctctg ttttttctac
     1981 tttgtctaat gcatgtgctt cttcatttaa ttctgtaccg tacaccgtaa accctttgcc
     2041 tttcattaca gggattacat ctgccaaatc tttttgtaac acaggcaaat gataattgct
     2101 tccctgcatg cttcgcagca cctttgtact ataaatatct gccgttcctt tacctaataa
     2161 aacaccagcc ataccaaacg catctgccgt acggatcatc gttcccacat ttccaggatc
     2221 ctgtacatta tctagtaaaa gccagcctcc tgaaaaatct ggcgtatctt cagatgttaa
     2281 cgtcatcact gctaagatcc cttgcggtgt aggtagatct gacatagcgg tcatgacctc
     2341 atctgaaact agaaaagtag aaatctcttt gtttacagcc agccagtctc cccattcttt
     2401 catacctctc tgtgtcacaa aaagttcttt tatttctgca tcagacgacg cagcttcttc
     2461 gatcagatgg aacccttcca aaagatattc tgccttttct tctctgtatt tctttttatg
     2521 tagttttttt aattctttga ttcttggatt ttttgctgat tggatctctt tcacattcct
     2581 tcacctcacc tgattatatc atggaatagg tgcttgagct tgtttcatcc taaaaaaatc
     2641 ggtatcattg atttataaaa caggaaagaa aggtgacgaa catgcgcaaa gttaaaatga
     2701 atgtccaagg acgtgtccag ggcgtgggat ttcgctatat gaccaagatg gttgctgatc
     2761 agttaggcgt gaccggaacg gtaaaaaacg aagacgacgg ctcagtcaca atcgaagcaa
     2821 tcggaaatga cgacatcatc caaaaattta tcgaagaagt caagaagtct ccgagcccaa
     2881 gtggacgagt gcagtatgtg gatgtccaag aagatccgat gattgaggaa cgaaagaaat
     2941 ttgatgtggt gggataaggt tgtgaaaagg tcgcttagtt ttgagtatta aggaaaattt
     3001 tgtgaaaatg gctttccaca tttttgcata aatttgactt aataccgaga aactgacttt
     3061 tgaacaccgt cgataaggtt gtttttgaag cgctttgcct cgagtattaa ggagaaacat
     3121 tttcaaaata gcttctcata ttttgaaatg taatgactta ataccgagag gcagctgata
     3181 aaacaccgtc aataaggttg tgaaaaagct ggtctgcatc aagcattaag gactggttgt
     3241 gaaaaagtcg cttagttttg agtattaagg aaaattttgt gaaaatggct ttccacattt
     3301 ttgcataaat ttgtcttaat accaagaaac tgacttttga acaccgtcga taaggttgtt
     3361 tttgaggcgc tttgccccaa gtattaaaga caggtagtaa aaaagctgat ctatcacttg
     3421 cagtgagttc atttgactcc tctatttcgg gcagaataaa aaaagttttt agttttttaa
     3481 ataagaaaga aacacttgga atcactcttt tctttccaag tatttctttc ttgatttttt
     3541 gtcttttttc aaaatttttc gctacgaaaa agaaagaata tttatatgaa atttctatga
     3601 agttgattga attccatgcg cttttttagt atagttaagt ttgtgtaaaa attatagaag
     3661 aggaagtatt ctatgaataa atggaaaaac tggttattgg gatccggact tgtcagtatc
     3721 ctgctctttt tatctggctg tgtgcggatg gattcaaacg gaaaccctga cacttcagga
     3781 atcgtttatc gagtactcgt ccatcctatg ggccaagcga ttacatatct agttgagaat
     3841 ttcaattggt cttacggctg ggcagttatt gcaatgactg tgatcgtccg tatcatcatc
     3901 ttgccactag gtatcagtca atcaaaaaaa acaatgatcc aatctgaaaa aatgcaagcg
     3961 ttaaaaccac aagttgaagc agcacaacaa aaactaaaag ctgcaacaac acgtgaagaa
     4021 caaatggcag cacaagcaga aatgcaacaa gtatatcgcg aaaacggatt gagtatgacc
     4081 ggcggaatcg gctgtctgcc tctattgatc caaatgccga tcttctctgc cttgtatttt
     4141 acggctcgct acacagaagg tatccgtgaa tcatcttttt acggcatcga tctaggctca
     4201 ccaagtatgg tgcttgttgc cattgcaggg gtcgcttatc tgcttcaagg atatatttca
     4261 acaatcggta ttcctgaaga acagaaaaag acgatgcgta cgatgctgat cgtctctcct
     4321 gctatgatcg ttttcatgtc gatcagtgcg ccagccggtg ttacacttta ctgggtagtg
     4381 ggtggtgtgt tcagttgtct gcaaacattc atcacaaacg ttatgatgaa accacgtttg
     4441 aaagcacaag tggcagaaga gttgaaacaa aatccgccaa aacaagtcgt cactccaaga
     4501 aaagacgtga cagaatcggc aaagccagct gacaataaac aaccaaaaaa cagtacaaac
     4561 aacaaaggcc gcaacgcagg aaagcagcaa aagcggaaat aaaaatatat gacaaaaaac
     4621 tgtagacaaa taaaaaaatt tctttgttct acagtttttt tgttacaatc aaagaaaacg
     4681 tcgcttttcg aggaggaatg tataatgatg tccaaataat caatggatag tcgaatggaa
     4741 gaagccaaaa tttcgctaga tgcacttgtt cctaaaaatc atttggtcca taaaattgac
     4801 aaaatattgt tatttgattt tatttatcca attgttgaat caacttactc gaccattggt
     4861 cgtcctagcg ttgatcctgt catcttagta aaattagtat tcattcaata tttatttagg
     4921 attcgttcga tgcgtcagtc cattaaagaa gctgaaacaa acctagctta tcgttggttt
     4981 cttgggctta gtttaatcga taaaattcct catttttcaa cgtttggtaa aaactatgta
     5041 cggcatttca gagaaaccga ttgtttgaac agatatttat cattatcctt gaacaagcag
     5101 ttgaagctag atttattcat gaagaaattt tgtatatgga ttcaacctat attaaagcga
     5161 atgcgaaaaa acatattttt acaagagaaa tggtacataa ataagccatt ttataccaaa
     5221 aacaattgaa agaaaaaatt aatgaagcaa gaattgcaga aggcaaacgt ccttttggtt
     5281 caatcattca tcaggaggtg gtagaaggga aaattagtgt cgcagatcca gaaagtggtt
     5341 attatgtaaa aacagaacaa gaaaaacagt ttgcttattc tgctcatacc gtttgtgatg
     5401 aaaatggttt tgtattagat gtcatgatta cgcctggaaa tctacatgac agccgaatgc
     5461 tcgtgccaca aatcgaacgt gttaaatcat gttgtggtgt agctgctgat gctgcgtaca
     5521 aaacaccttg gaacgccaag tatttaatcg atcgaaaact acgacccatt tttccttata
     5581 ctcgacccaa aagaagcaaa gaacgtttta aaaagaaaga tttttattat gatccctatt
     5641 ataactggta cctatgccca aatgatcaaa cacttcagtt tcgcacaact actcgagatg
     5701 gttataaaaa atatgtatct aaatctttta tttgtgaaag ttgtctatta ttgaaaaatt
     5761 atacagaaag ccagaaacac cagaaagaaa tacatcgaca tatttaggaa gactacttag
     5821 atgaagcaga acatttacgc catacggtgt acaatcgcga aaaatataaa aaaaagaaaa
     5881 gaaacgattg aacgcgtttt tacagacgca aaggaaaagc atggaatgcg ctacaccaaa
     5941 tatcgaggct tggaaaaaac caggtgcata cgatgcttgt ttttgccgca atgaatctgc
     6001 aaaaattagc catttggcag tgggggcata tgtct
//
LOCUS       DAZKPE010000115         6017 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000115 DAZKPE010000000
VERSION     DAZKPE010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.117"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(115..495)
                     /gene="yajC"
                     /locus_tag="ACG930_002755"
     CDS             complement(115..495)
                     /gene="yajC"
                     /locus_tag="ACG930_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFQ0519868.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(592..1737)
                     /gene="tgt"
                     /locus_tag="ACG930_002756"
     CDS             complement(592..1737)
                     /gene="tgt"
                     /locus_tag="ACG930_002756"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFQ0519869.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1955..2653
                     /locus_tag="ACG930_002757"
     CDS             1955..2653
                     /locus_tag="ACG930_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFQ0519870.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(2821..5460)
                     /locus_tag="ACG930_002758"
     CDS             complement(2821..5460)
                     /locus_tag="ACG930_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFQ0519871.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
BASE COUNT         1691 a         1320 c         1105 g         1901 t
ORIGIN      
        1 ccgattattc aatattgagc aatatatccc atgctcttat ctctttcttt tttgaataaa
       61 aaatgaggta ggacatcttt ctgccctacc tcgtctttaa ataagctttg atacttattt
      121 ttcttccttc tcttctgtct cttccagcgt ttctgttgtt tcagttttta cttcaactgt
      181 ctcagctggt tcttctgttg tttcaacagt agtcgttgca tcatttgtta cgacagtccc
      241 tggtttgacc gttttgattg ctgcacgatc gtactcaagg aagatccctt cgcagtctaa
      301 aacaactgtc cgtttgtcat tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt
      361 tacgactgaa tcacctggtt tcatgctatc taacaagttt tgacgttctt gctgttgttt
      421 cttttgcgaa cgtgacataa aaaaccacat tgctaatagc gcgataaaca tcacaagcat
      481 tggtaatgtt cccatttttt tcacctcact aattctgtat ctacaaaaaa cactttagca
      541 gaaaaatgct gataacacta gttttttact taatttttaa aagattttcc tttagaagct
      601 ttttgcgttt tctttattga acccgtattc ttcaaaaaag gcttctctaa attcaagcaa
      661 attatcatcc atgattgctt gacgtacttg tttcattaga ttcaacaaga agtataaatt
      721 gtggtaagaa gtcaaacgaa tcccaaatgt ttcatcacat ttgatcaaat ggcggatata
      781 ggcacgtgta tagtttttac atgtataaca atcacatttc tcatcaattg gacggaaatc
      841 atgggcatat ttcgcatttt tcactactag acggccttga gaagtcatac atgtgccatt
      901 tcgagcgatt cgagtaggca agacacagtc aaacatgtct actccacgga taacaccatc
      961 gatcaatgaa tcagcagcac cgacacccat caagtaacgt ggtttgtttt cggggatcaa
     1021 cggtgtagtg aattctaata cacgattcat ttctgattta ggttccccga cagataaccc
     1081 gccgattgag taaccaggga aatccatccc gactagatct ttcgcgcttt gacgacgaag
     1141 atcttcaaac cctgctcctt ggatgattcc aaataatcct tgacggtctg gattagcatg
     1201 agctttcaat cctcgttctg cccatcgaga cgtacgttct actgattttt tcacgtagtc
     1261 gtaactttca tcgaatggtg gacattcgtc aaaactcatc atgatatcag agcccaattt
     1321 attttggatg ttgattgctt tttctggtga taaaaacata cgcgaaccgt tcaagtgatt
     1381 tttgaaatgc acgccttctt cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa
     1441 gccgcctgaa tctgttaaaa tcggttgatc ccagttcata aatttatgca gtccgccagc
     1501 ttcttctact aagtcttcac cagggcgtag ccataaatga tatgtattac ttaaaataac
     1561 gccagcaccc atttctttca actcttctgg ggacattgtt tttactgtag ctaatgttcc
     1621 tactggcatg aacattggtg tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg
     1681 cgcgccagta tgtttttctt tcttgattaa acgatagcga atggcaggtt gcgtcattca
     1741 tttccctact ttctatataa aatatcttga caactcccac catcataatc gtttcaagtg
     1801 ctttttgcaa gttccctcgg cttccttcta ctttatttaa tattcttttt tttatccttt
     1861 ttttatgaat aacaaaaaaa agaaaaacat tatgacagaa atattttttg atacatggta
     1921 tattggtgtt attaaagaaa aggagggaaa aatcatgcaa tcttctgcag aattaaaacg
     1981 ccaagcaaaa gagagtctaa aaggacgttg gggacaagct gttttactaa atctaatccc
     2041 tacattgatt ggtattgcta ctattcttct tattatgatt cctattatct tgtttgccac
     2101 caccatatat gatggatcag cgagcgtctc agaagcgaca acttcaggag gcggtagttc
     2161 aggaggcggt ggcggaatta tttccagcat cattagcgct ttgttcatga gcggtatttc
     2221 ttggacttat cttgatattt tacgtggaca aaaagatcag atcgaaccat tcaaagatgc
     2281 atttcgtgga ttcaaaggtt tgtttatcgg cggagtgatc agcttagctg tgctgatctc
     2341 gatctttaca acattatggg gtttgctatt agttattcct ggaatcatta aaagctattc
     2401 ttattctcaa agctatttta tttactacga tatcgtccaa gaaacaggac aaacacctaa
     2461 agtactggat acgatcactg caagtcgaaa attgatggat ggttataaag gacaactttt
     2521 ctggttagat ctttcattta tcggctggca tatcttagca ttagcaactg ctggtattgg
     2581 ttatctatgg ctcagcccat acatttctgc aacaaaagca gcattttatg aacaattgcc
     2641 aaaagatatt taaaagagag tgtgacttgt gaccgagggg gtggcaggag aacaccgttt
     2701 atcgagaggc agtaaaagaa acattcagcc cattagcaaa aaggaggtgt gacaacattc
     2761 atgtcacacc tcctttttgt atagttccag taaaaagaaa atcaacttag aaacagttaa
     2821 tcattcctct tcttctgctt ccggtaatcg atggaacttg atcagttcat tcaccgcgat
     2881 tggtacgata gataaaatcc ctaccaagaa ccagtgattc aaactgatgt gtactaggcc
     2941 gaatagttct tgcgtaaatg gcagcaaagc aacagccgtt gtaatagcta atgccagtaa
     3001 cgccatttct accaaagctt tattggtcgc taaattgact ttgaagatcg attggctgct
     3061 gcgtacattg aacacatgca gaatcgatga ataagctaag atcaagaatg caacagtttg
     3121 accgacatgc tgacttgcgt ctacccatgg gctgatagta tcgacataac tacctaaata
     3181 ataaccaaac aaggttacga tggtgaagac ccctgcattt atggcaattt tttgcaataa
     3241 acctcgagca aagatccctt catttttcgg aatgggtggc tgatccatga tgccgtgttc
     3301 cgctggctct cttcctaaag caaatcctgg aagtccatca gcaactacat tgacaaacag
     3361 tagttgcaca gctgtaaatg gtgctcccca tcctaacagc atcgcaatca aaacaataaa
     3421 gatctccgaa atattacagc ttagcaaaaa gttgatagct ttacgaatat tctgataaac
     3481 cgaacgtcct tgactgacag cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat
     3541 atctgcggca ctttgcgcca catctgttcc tgtgatcccc atggcacacc caacgttact
     3601 tgctttcaac gctggtgcat cattcacacc atccccagtc atcgctacga ctgcacccgt
     3661 acgttgccaa gatttgacga tccggatctt gtcttctggc gttacccgag catagacaga
     3721 gagagctttg acacgcgcat ctaattcttc gtctgataat tgatgcagtt ctgatcctga
     3781 aagtgcttct gacggatcat tcaagatacc taattctttc gctatggcac tggcagtcac
     3841 cacatgatct ccagtgatca tgactgtttt gatgccagcc tttttcgctc gcttgattgc
     3901 tcctttactt tctggacgtg gtggatcgat cattccgatc agaccaatca aacgtaagtc
     3961 tttttccagt gcttcagaag aaatatcttg cggttcttcg tcataagtag cataaccaac
     4021 agcaatcact ctcagtgccc gtttaccaaa gcgatcatta acgatcgccg cttgttctac
     4081 atcgcctgaa ctaaagcgcg gagcaagaac atcgaatgct cctttggtga ttgagatgta
     4141 tttttcgccc atttggtgaa ctgttgtcat catttttcgt tcagaatcaa aaggaagctc
     4201 gtttactcgt ggatattttt cttctaattc tgcctttgta tgataattct cttcaacagc
     4261 ccttacgatg gctacttctg ttggattacc tttgataaca aggtcgtcat cttcttgctc
     4321 gaccgtcaca tctgtacata gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat
     4381 tgaatcttcg atattcgtta cttcatcttc tttgctccat acccggcgga cgcgcatttc
     4441 attttgtgtc agcgttcctg ttttgtctga gcagataaca ttagcggttc ctagcgtttc
     4501 aactgctggc aactgtcgga tgatcgcatg tttcctcgcc atcttctgca caccgtatgc
     4561 aagtgtcaac gtaacaataa cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat
     4621 cgaagtcatg aacatctcaa ggagtggttc tccttgcagt tcaccaatca caaatactaa
     4681 agccgcagcc gctaaagcga tcatactgat tcgtttgcct agctgattca atcggacctg
     4741 taaaggtgtt ttttgcatag tattttcgtt caaaagatcc gcgatcttac ccatttctgt
     4801 agccatgcca atggcagtga cgatcgcttt cccacgacct gcagcaaccg tacatccttt
     4861 aaataccata ttaagttggt cacctaatga ctcatcttct tcagcaataa atgctgcatc
     4921 tttttcaact gcttcacttt ctccagtcaa cgccgattct tctacacgta attgtgatgc
     4981 ttcgatcaaa cgggcatcgg cagaaatagc atcaccggac tctaaaacaa gaatatcacc
     5041 cactaccagt tgctctgact caacagtggt cactttgccg tctcgtatga cagttgccgt
     5101 ttgtttattc atatcttgca aggattccag tgctttttct gcgtttcctt cttggacaat
     5161 cgccaatacc gagttgatca caacgatagc gatgatcagc agtccttcaa ataaatcccc
     5221 atgttctgta gcaaatgcgg tataaaagga aatcaccgct gctacaagaa ggatgatcgt
     5281 tgtaaaatcg gacaagcttc gaaagaattt tttgatcatc gattctttcg gcgcctcatc
     5341 gaatttattc aatccctgct tttttcgccg ttcatccact tcttgtgaag acaacccagt
     5401 atctggatct gcttctgtta ccttctttac ttcttctatt gtctgcttgt attcttccat
     5461 cctattcctc ctttaaaatc ttcgtacaaa aaaaggtact tattttacta taacatcctt
     5521 tttttattta cttcaaataa agggcttatc gattatttgt taagaaagcg taaaatttaa
     5581 agtgcttata tttgcaaacg ctaccaaagg atgctattat atagatgtaa ggaaggagga
     5641 taccatcaaa tagacagaag aatttctcga tagaacagtg taagcaaaca aagttgttag
     5701 aagtacaggt ttcacccaga catgcgtgta gagtacaaac ctataaatag tgaatgcgta
     5761 tggatgtttg gatcacgaag tatccgaaac aagaagtaat gcgatacgta acaattgaat
     5821 aacgtaaacg tctgaaaatt gaataggaac aagagatgtt tcaaatgttg aagatgtaac
     5881 gaaaacaaaa tttttgttta acatgaagaa attcaacacc gtgctttgca tgtatgatgg
     5941 aaagttacaa tcatttctgt ttatttgaat ccttccgagg tacaagaaag ccgagcttat
     6001 cgagagctcg gcttttt
//
LOCUS       DAZKPE010000116         5974 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000116 DAZKPE010000000
VERSION     DAZKPE010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.118"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            142..747
                     /gene="fic"
                     /locus_tag="ACG930_002759"
     CDS             142..747
                     /gene="fic"
                     /locus_tag="ACG930_002759"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFQ0519872.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            763..1335
                     /locus_tag="ACG930_002760"
     CDS             763..1335
                     /locus_tag="ACG930_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0519873.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1587..1844)
                     /locus_tag="ACG930_002761"
     CDS             complement(1587..1844)
                     /locus_tag="ACG930_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519874.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1970..2785)
                     /locus_tag="ACG930_002762"
     CDS             complement(1970..2785)
                     /locus_tag="ACG930_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519875.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3302..4627
                     /locus_tag="ACG930_002763"
     CDS             3302..4627
                     /locus_tag="ACG930_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFQ0519876.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            4620..4970
                     /locus_tag="ACG930_002764"
     CDS             4620..4970
                     /locus_tag="ACG930_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519877.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            4967..5137
                     /locus_tag="ACG930_002765"
     CDS             4967..5137
                     /locus_tag="ACG930_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519878.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
BASE COUNT         2074 a          929 c         1090 g         1881 t
ORIGIN      
        1 ctagactgtg caaaatagag acacttgaaa aatctatcgg gggtcagaaa cttaatagtt
       61 tttgacacat aaacaaaatc gcgatataat ggggttgaga gtgtttcata aacttatgtc
      121 ataaagttaa ggagatttcg catgatttta gagaataaat tgggattaac caatcaagtt
      181 gagttggcta aggttgaaga aaaactcagt aaacaaaaag cgaaagaatt gtacgattgt
      241 ggaaaaataa atgaaatcga agttggtaca tttaaaggtt tatctgaaat tcatgaattt
      301 ctattttcgg atatttacga ttttgccgga aaaatccgat cggtcaatat tgcaaaagga
      361 aattttcgat ttgcaccagt tatgtattta gaacattcgt tacagcatat tgatcagatg
      421 ccacaaactt cttttgaaga gattatcaag aaatatgtgg agatgaatat cgctcaccca
      481 tttcgagaag gaaatggccg aagtactaga atttggctgg atctcatttt aaaggaagaa
      541 ttgcaaaaag ttgtagattg gaacttaatc gataaagcag actatctttc tgcaatggag
      601 cgaagtccca taaacgattt ggaaatacgc tatctaattt ccaatgctct gactgataaa
      661 attgacgatc gcgagttata tatgaaagga atcgatgtca gctatttcta tgaagggtat
      721 tctgagtata cgatagatga tttgtaaaag taggtggacc aaatgacgaa atatggatat
      781 gcacgtgtct caaccgcttc tcaaagtaca aaagaacaaa ttcaacagtt gcttgagaac
      841 ggcgtagaga agaagaatat tttttcagaa aaatttacgg gtacaaaacg ggatcggcca
      901 aaattcaatc agctgttggc tggtctgaag cctggagatg aaatagttgt tacgaagctt
      961 gatcgatttg ctcgtaacac gagagaagca ttagagatca ttgaaccttt actcgatgat
     1021 aacgtaacga tcaaggtttt gaatctagga acgattgaaa atacgtccat ggggcgaatg
     1081 gtgacacgga cgttgttgag tgtagcagaa atggaacgtg atatgattgt ggaacgtacc
     1141 caagaaggaa aaatgtttgc aagaaagaat aatcctaatt tcagagaagg acgtccgaaa
     1201 gcaacaatca caccgaagaa gaggcacgca tatgaactgc ttacttcagg taaatcgtat
     1261 aaggaagttg aagctataac cggtttcagt cgcagtacgc tttttagaat aaagaagaaa
     1321 attgaagaaa gttaaaaaag aagtctcagc gaaccagaca ggtaaatact taatgcgttc
     1381 tagatatgag tctattagca tgttgtgaaa tataatattt ttttatttac ttgatttctg
     1441 ctcaaaaaat gtgtatggta actgtaaaag gtaaagtaat taaaggtatg ctagccacgc
     1501 ttactatatt aggataccat catatattta taatgaacga tttgttcgtc taccaaacaa
     1561 cacatatcgt tcagcgtaag tcacgtttag gaacgtggct tttttagtgt tattatcgat
     1621 aaataatcta ttgactctat tgattttatc tccatatccc tacggtgttg attgtcttta
     1681 gatctttcat ttaagaacca aataactatc ataaaaatca gcactgctgc taatataata
     1741 aacagcattc ctattgtgat attacctatt gattttacca taactacgat taaagtaata
     1801 atggcattca agtctccttt gttctctata tataaattag ccataaatca tcttcctttc
     1861 aaattaagat acttgtttga taccaataaa tagtaagcgt ggctagcata cctttttctg
     1921 taatagcaag tgttctaata gtccaaactt aatgatggac cgatgctagt tatagtacag
     1981 taatgttttc tttcttatct agatttttag taagctctat cagcaaatct aacaaatctg
     2041 agtccttttc agaaactaaa ttaaatctag tgtttacaac aaagttttca tgttctatat
     2101 tgtttagatt atttgcggaa aggagggctt ctagatcttg acattcaaat ctatatgcat
     2161 cgtcataaat cttactagaa ggagtgctta attcgaaatt acttattttc tcatcttgga
     2221 ccaagataaa tttatagata gtatcttttt gtgtttttct tttaaaaaca caacagagtg
     2281 tgttataagg aacgttataa ttttcatcag cctcattttt tctccattca aacaaatgat
     2341 aaactgcaac caagttgcca tcaatttcat ggacagtgct ctcggtaaca tcctttaaag
     2401 aactatcaag ggctaattta tagtaactag agagaggaag taaaattgtc gatttactga
     2461 gatggttatc gtctatacgt gcaatcatac ctaaatcaac taaggtttta ttccaggtgt
     2521 ttatagtttt agttgtcact cctagagact ctgctatggt attgaccgaa tgccaggaat
     2581 ccccgccttc attctttgcc ttaaaacagt aatacagata taaattaata gctttgttat
     2641 tcggtaaata tttttcaagt tctgttggta gaataaagta agaatcctta atgttttttc
     2701 tgaactgtct ccagtctctg tagttttgtt tataaagttg tgaaacggtt tttccacctt
     2761 tagaaagtcc tgctatctta accaatctta ttgctccttt cttgaatctg tcatgatcat
     2821 acagtatttt ttacttgtag tccagcacct taatatatta tcctatgtaa ttaatttcgt
     2881 actagatagt aattattttt tatttaattc tctagtcact tacaaataag ttatataaac
     2941 tacgattaat aaattattac aaaaactatt aagaaaactt ctacatacaa ctattacaaa
     3001 actattaaga aactgaatac tcctattttt tgtttttaag gaaagttttt tcttttttga
     3061 atttcttatt tttttctaat ataactaagc aaaactggat aatacgacac ttattttcaa
     3121 attttcacaa gactaatagt aaatatccat ttaataaagt gatacaatgt gttgatttta
     3181 caaatcaaca gaagaagtag ggaaataact tacctatgct tctttttttg tacatttaat
     3241 cgattcttct ttacaaaaac gaacgtatgt ttgtataatg tggaagaatg gagtgttatt
     3301 tatgatggat tattcaaaag agccagtaaa tgattacttt ttgatcgata tgaaaagctt
     3361 ttacgcaagt gtcgaatgta tagaaaggaa tttagatcca ttaacgactg aattagtcgt
     3421 catgagtcga gcggataata caggatcagg gttgatttta gcttcttcac cagctgcaaa
     3481 gaagaagtac ggtatttcta atgtcagtcg accacgagat ctaccgcaac cttttcctaa
     3541 aacgttacat gtcgttccac cacgcatgaa tctctatatt aagcgaaata tgcaggtaaa
     3601 caatattttc agaaggtatg tagcagacga agatttattg atttactcga tcgatgaatc
     3661 gatcttaaaa gtgaccagat caatgaatct ttttacgact gaaggaacaa gaagtcaacg
     3721 gagaaagaag ctggctcaaa tgatccagga gaatattaaa gaagagctag gattgcttgc
     3781 tacagtaggt gtcggagata atcccttatt agctaaactt gctttagaca atgaagcaaa
     3841 acataatgat ggattccttg ctgaatggac gtatcaaaat gttcctgata aagtatggaa
     3901 tattcctgaa atgacagacc tttggggtat tggatctcga atgaaaaaaa gactcaacca
     3961 aattggtatc atgagtatta aagacttagc taattggaat ccatacacta ttaagagcca
     4021 tttaggtgtg attggcttac agctgtattt tcatgcgaac gggatcgatc gaacagatat
     4081 agcgatccca ccagaaccga caaaggaaaa atcatatggt aattcacaag tgttaccacg
     4141 agattatacc aggagaaatg aaatcgaact ggtggtaaaa gaaatggcgg aacaagtagc
     4201 tattcgtatc aggcaacata actgtaaaac aggttgtgtc catttataca ttggcacgtc
     4261 gatcttagaa acgagaccag gtttttcaca ccagatgaag atccctataa cagataatac
     4321 aaaggaattg cagaattact gtcttttctt gtttgataag tattatgaag gacaagaagt
     4381 aaggcacgtt ggaataacct atagcaagct tgtgtacact gattcgcttc agctggattt
     4441 atttagtgat ccacaaaagc aaattgacga agaaaattta gataaaatta ttgacaagat
     4501 tcggcaaaaa tatggtttta cgtcgattgt acatgcttct tctatgttag aaggcgctcg
     4561 tagtattact agaagtacat tggttggtgg ccatgcaggc ggcgcaggag ggcttaaaaa
     4621 tgattgatta taatgatcgt ggacgtttaa agtgggcagg tttttattta tctgatcata
     4681 ctgaaaaaat tgatgccgac aatgaacaac gagccaatca aaatttggca aaagaacaaa
     4741 tgacgactga agaggttgcg gaagtattga acgctgcagt cataaaaaat agatcagtat
     4801 gtattcaaaa agaagaacga aacgctgaag gatactatcc agaagatatt gttagcaaga
     4861 tcttaggtag tgatgagctg gggatctacg ttggaaaaaa caaagttcac tacgacgaaa
     4921 tacgtcatat cgaattttac caggataata aatggggtcg attagaatga acattatcca
     4981 gcaatatgag ctaaagtata taacctttga tcagctatca gaagagattt ggggttatgg
     5041 ccagcgtttg ataaatgagg ttggtgttga acgcttctct ttctatgtag aagctgcagc
     5101 aggataccat aaatacgaat actatattgg ctattaaagt gcaataaaat tatatttctt
     5161 ttatgtttta cattttgtat caattctgat aaaattacct ataggtaatt aaaaaatata
     5221 aaaaaactag ttacaacctt aggacgttgt aactagcttg aagcatacta gagctaacta
     5281 aaatagcact agaaagcaat gttaaacccg tccaacaaac ttgatttaac attgagacca
     5341 gcttattcag ctaaatatag ttgaataagc ttcttttgtt ttaaaaaaac aaaaggtgta
     5401 ctacgaataa cgcaagtaaa agaaatacta ttacaaccag taggctacaa gtaagtatta
     5461 ctaaacattg cgtagttaga acctttgctc tattgtctaa agccacaaaa ttagagatca
     5521 gctttatgat gctaagagcg agctgcatcc atgcggacat aggttctttt gacactatta
     5581 attctccttt ttaggataag ggaaattgct agtagttttt tcattagcac catccccctt
     5641 catttgattg agtctagtgc tgctgtgata gtttgctgtt taatatgctt acattcttat
     5701 tataacataa atgaaacaaa cacatggtta gaggtcgtat caatcaaaat agtgtctcac
     5761 aaacgattta ttacttactc ctgctgacta acggactgtt cttcagtaac tgtaactata
     5821 tgtttgttaa aaccaccatt acctgtagat aaaaaccaat atatttacta tactcactat
     5881 attaaatata tttagtatag taaaaactag aaacaataaa atttgtgaat gttgtatacc
     5941 cccaaacaat acacatattt tgaaggatta ggat
//
LOCUS       DAZKPE010000117         5809 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000117 DAZKPE010000000
VERSION     DAZKPE010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.119"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..941)
                     /locus_tag="ACG930_002766"
     CDS             complement(<1..941)
                     /locus_tag="ACG930_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0519879.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKD"
     gene            complement(1053..2027)
                     /gene="sgrA"
                     /locus_tag="ACG930_002767"
     CDS             complement(1053..2027)
                     /gene="sgrA"
                     /locus_tag="ACG930_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFQ0519880.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(2223..3062)
                     /locus_tag="ACG930_002768"
     CDS             complement(2223..3062)
                     /locus_tag="ACG930_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFQ0519881.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNRTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3247..4134
                     /locus_tag="ACG930_002769"
     CDS             3247..4134
                     /locus_tag="ACG930_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFQ0519882.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEGAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(4728..5423)
                     /locus_tag="ACG930_002770"
     CDS             complement(4728..5423)
                     /locus_tag="ACG930_002770"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFQ0519883.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(5407..5805)
                     /locus_tag="ACG930_002771"
     CDS             complement(5407..5805)
                     /locus_tag="ACG930_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFQ0519884.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         1793 a         1165 c          901 g         1950 t
ORIGIN      
        1 tcatcttttg tgacgtaact caaaaatact tccattggtg tccgatagtg taatgatttt
       61 ctaggaatat gatttcgttt cgatgccacc gattggataa aggtttcaga tacaccatta
      121 aaatccatag ctttatacaa accatcttta cgtaataagc catttgaatg ttcattcaat
      181 cctcgttgag aaggtgttcc tggatccgca aaataaattg aaatatcgtt ggtattacta
      241 atctttttcc aatttgagaa ttcttttcca caatcaaatg tgatggattt aaataagttt
      301 tttgggacac aacgaaacca ttgattcagc ctattttcaa tgtctttagc ctgtctgcct
      361 tcgggtttca aggtaatgat gactttagat agccgttcaa ctaatgtgat gaccgcgctt
      421 ttatgttttc cacccacgat agtgtcacct tccaggtgac caaattcatg atcaaactgg
      481 gtatagtctg tctttctgtc tcggattgac cggcgaaacc cttgttttcc tcttttttct
      541 ttatgaccgt ttggttttct ttttcccttc attggtaaat cgtgagtgtc aaaggtttta
      601 tctttaaaca ttcgatacag tgtgcgtacc gaacaagcaa taggaaactc tgctcgacca
      661 ataaggacat caggagccca cccttgaaca accttttttt gaatgtattc ctgttgctca
      721 tcaggtaaaa caatcggatg tcttccgcag ttacgtttgt ttttcttata ttgtttatag
      781 tagctcattg cgcttccacc agatttaaga aaacgataga ccttataaat agtttgtcga
      841 gaacgttgta acagattggc tacttttgaa acaggttgtg attgattgaa ataagcttct
      901 atcattacga gttcagttgg tgtaagatgg ttataggtca tttgtactca ctccttataa
      961 ttctttcgtc ggaactattt tgagtgtagc acaaatgact ttttttagtt gtctagctta
     1021 attttacaat cggcgtctgt tgcttttatt ctttatttca ctcgatggaa gagagaacga
     1081 aaatagcttg ctcctacaat caaaatgagt aacacaccca tccatgtaat tagcttgttc
     1141 aaggttctac taccagtttc tggtaaatcg ctttttctat tatctgtttc tttcgctttt
     1201 tcttgatgat caattccacg agaaacaaaa tcaggctgtt ttagcacact ttttaggttg
     1261 ctccctgcat ttctcttttg ttccttagtt ggtatgatag gtaccaaatc aagttcatta
     1321 tttacttttc ctgtgctgct ttcgctgctc gtgcttcctg tgctactctc actactcatg
     1381 cttcctgtgc tactttcact actcgtactc tccgtactgc tttcgctgct cgtgcttcct
     1441 gtgctacttt cactactcgt actctccgta ctgctttcgc tgctcgtgtt ttctgtgcta
     1501 ctttcactgc tcgtactctc tgtactgctt tcaccgctcg tgttttctgt actgctttca
     1561 ctacttgtgc tatccgtact gcttggcggt ccaacaactg tccaactgct tggtttcaaa
     1621 ttctccgtga tcgtcatctg tccatcataa aaaacaatca aatcaacttt atctttactc
     1681 ttgatctcat caatcgatag ttctgcagaa atcattattg tatactcaat accagcggtc
     1741 cattgtacgt cttttaaata aacttcccca ataacttttt ctgaacttcc attaccatcc
     1801 caaccatatg ttagaacagc atgtacatca ctagcattca cgcttttgtt tggtttgact
     1861 ggaatagtaa tgacttgttg tgtcatgtca taaacaatcc gatcagtttt cacagtaaat
     1921 gaaagattct catttgcccg ttcatttgca gaagtactga ttccaatcat tgctgcaatt
     1981 atactcagcc caagaataac aaataatacg gtcgctgttt tcttcatttc tatcactctc
     2041 catataatta ccttctattt gataaaggaa ttatataaaa tgaaaatgat gagaacacga
     2101 cagtcagttg tgaaaatcta acaaaagatg tcgtgtattc gcttgaattt gtttactttt
     2161 tcgtttaatc aatgacagac ttaaaaaagc aagaccgata tcagccttgc tttcttcatc
     2221 ttttattgat aaacagcagt gtatttcttc atccgctttg ttttatatgc atagagtaac
     2281 aaaccaacaa tcaagactaa caagaataat gtagttgata tagatgcttc agccccaaag
     2341 tttcccccag taattattgt attttgcgat tggatcagag tggagaaaaa accttgttct
     2401 tgcgttccgc tgactggtat acccaaaata gctccttgtg tccgattcca agtaatatga
     2461 gcaccaatag ccgtaaataa acttcctgta ctgtagataa gtgcgctgaa aaagcaacct
     2521 gctaaaaaga tattgaaaac tgccagaaat gtcatgttag gattcaatcc gtgcaaaaga
     2581 gcaaataatg cagcagatcc aatcattgct attaacggac caaatctaag catctgatgc
     2641 tgaaaaaagc cacggaataa aagctcttct gatgccccca ctgcaataaa taaaataaaa
     2701 ctcgttatca gcggcacaat gtttgcgttt cctgaatcta accgatacgc ccccgtcaaa
     2761 tataatggac tagtaataag cagaaacact ccaattccaa caacgagacc tcccgctaaa
     2821 tacccccagt cttttcctcg aacagaaaca ccataatctt ctattctttt tccttcgacc
     2881 ttactagcaa gaaataaagc tagtaaaaaa acagctaaat gtccgaccgt accggcaatt
     2941 gctccaatcc attcactatt tccaataaac atatccgcaa gtgcattatt gacaagaatt
     3001 cctaaaacaa aaccaactaa gactattaaa acagatccaa tcaaccgaat aatcctgatc
     3061 atctttcatc cctcctttat attaagttta acaacccttt tctttcttgt ctcgtgaaaa
     3121 ctatgtaaat gttctccatc atagagagaa tagattttta cgaactaaga atatctacag
     3181 caaccttacg aaaatgaaag actgtctccc taattcttct gttagactgt ttttaataag
     3241 gaaaggatgg gaaatttttt gaaaaaacaa ctactaatta tgtgcctttc agcatgtgca
     3301 attttactat tctcaggttg tagcaagtcc aatgaaacga ttgcaacgtt taaaggtgga
     3361 acacttacag ttcaggattt ttatgataac ccaaaagtta aatcaaataa tcaaacacta
     3421 ttaaaaaaaa tgattgtctt caaagcattt gatgatgtat acggaaaaga gatttcttca
     3481 aaggaagtaa caaaagaata taatgaacaa atcaaaaaac tcggtccaaa ctacaaggaa
     3541 caattaaaag cagttggcca aacagaagag acatataaga aactctttaa acagatgctg
     3601 gctttccaat acggtttgaa agccaatgta aaattaacag ataaagatct agacactgct
     3661 tggaaagaat tctatccaga agttagtaca cagatcattc tattttcgac taaagaagga
     3721 gcagataaag caaaaaaaga agcaaatgaa ggagaaaatt tctccaagct tgttcaagct
     3781 tatggaaaaa ataaaacatt aaaggaaact gatggaaaaa tgaattttga ttcaaccaat
     3841 ccagagattc ctactgaagt aaaaaaagca gcatttaaac taaaaaacgg ggaagtttct
     3901 gatatcattc ctgtaacaga tccaacgact tatcagcaaa gctattatct agtaaaaatg
     3961 gtaaaaaaac aggataaagg ttctaataaa gacaaataca aatctgagct agaaaaaatt
     4021 gctaccgaag caaaaactct tgatacggaa ttcatggata aaacaatccg taaagtgatg
     4081 aaaaaagaca atgtaactat taaagatcct tatgtaaaaa atatattcaa ataaacaaat
     4141 ttgacccaat tggggatgtg gcaaaatttg agaagtgatt tttggaaatt ccttcttatt
     4201 tttgaggcaa accacttttg ccacaacttc atcggggcct ttttttattt gtaccaaaac
     4261 aaatcactgg atttgttaca atcatgagga tataatttaa aaaagttttt tatttctatc
     4321 acatgaatca atgcgccatt aagtagattc tttcatgctt ccctattttt tcacttgccg
     4381 tatcgcttca aaaacaacta tcataaactc aaactcgact gaaaagttat tttaaaaaag
     4441 actaaaaata tcccttctgg acttgttctt cttattctgt tatactagag aaacacgaaa
     4501 gatattttta tgcgacactt ttcatttgtt tttatgaaat ttattcaaaa ctggcgtaac
     4561 ttcagagtta caaggatgta ttagaggtta gggaatacat cgtttaaatg agaaataagt
     4621 aatagttagt aatagtcacc caaactttaa attaatgaat attgaatcgt cagatagcct
     4681 cctcgagttt tcgagaaggc tatcgtttat tttatggaga aattgattca gaagtaatca
     4741 gcgacctttt ttagttcacc aatcgtttct gcttggaaag tttgcaccca atcttcttgg
     4801 aagcccctca ctgctttatc aatcgagggc atctctaata cttgatctag tagctcttta
     4861 cctaacgtta tcgcatgagc tccagatcga atggctgtag tgacttgttc acaatttttg
     4921 aaactagctg ctaatatttt tgttggtctt tgcgtacgtt cgatctcagt ccgcaacgaa
     4981 tcaatcactt tcatagcatc aatgccttga ttttgcatcc tgttataata aggtgcaata
     5041 taatctgctc cattattaat agctaaatac ccttgtaatt ctgtgtaaat agctgtaccg
     5101 gtaatcaaat aaccttcttt tttcaacttt ttgatcgctt gaaggcctgc ttgattcacc
     5161 ggcaccttga taaacgtatc ttttcccagt tcttctatga taactcgagc atcctctatc
     5221 atttcttctt ccgttcttcc tattgtctga atatggatag gaatctgtcc gattattttt
     5281 ttgatttctt tcatatgcga gaagaagttt gacgctcctt cttttttcag aattgtagga
     5341 tttgttgtta cgcctgttaa attcaaaaac tgttgacaag aataaatact ttttgtattt
     5401 gctgtatcaa gcatgatttc catatagctt tcccccattc tgatcctctt gatcgatttt
     5461 aatgattgtc ccctttctta aatgcggcat ttccttatct tctacataca ttgttcctgg
     5521 aagttccggc tcatgagatc catcaaattt tatcgtgata tgtcctaatt cattcaaatt
     5581 agtttggaca acatctccta ctgctgtgat tacatacatt tgtttatcaa aacagagctt
     5641 catatcacaa gttatttctt ttcttacctg attcaattca atcttataac aataatctgt
     5701 taatgtttcc ggtgcttcat ctccaaataa aatcattatt ttttctttcc tgaatacttc
     5761 tgcttctata ccaacatctg ttacaaccgt ttcaaagatc gtcatctct
//
LOCUS       DAZKPE010000118         5709 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000118 DAZKPE010000000
VERSION     DAZKPE010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.120"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..778
                     /locus_tag="ACG930_002772"
     CDS             <1..778
                     /locus_tag="ACG930_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFQ0519885.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(920..2728)
                     /gene="pepF"
                     /locus_tag="ACG930_002773"
     CDS             complement(920..2728)
                     /gene="pepF"
                     /locus_tag="ACG930_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFQ0519886.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2904..3902)
                     /locus_tag="ACG930_002774"
     CDS             complement(2904..3902)
                     /locus_tag="ACG930_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFQ0519887.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(4128..4781)
                     /locus_tag="ACG930_002775"
     CDS             complement(4128..4781)
                     /locus_tag="ACG930_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFQ0519888.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(5113..5511)
                     /gene="spxA"
                     /locus_tag="ACG930_002776"
     CDS             complement(5113..5511)
                     /gene="spxA"
                     /locus_tag="ACG930_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFQ0519889.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1721 a         1155 c          914 g         1919 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatgtca atgatattgc
      541 catttatttc gctgatccag gaacgccgtc tcaaagaggc ctaaacgaga attctaacgg
      601 attgttacgt agagatggtt tattgaaatc tatggatttc aattcagtag atgaattttt
      661 tattcaatct gtcgcatcta aacgaaataa tattcctaga aaatcactgg attatcgaac
      721 acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaact taatttgaca
      781 attaagaata caaaaaagat gttggtgaag ttcaccaaca tcaaaaagta tagagcctta
      841 aaaaaatacg tcgactccct tacaagagag ccgacgtatt tttttcgttt ctattcgaga
      901 aaatcaaaaa tagaaagcct tataaacgat cgatcaattc ttctaattca tttagacgtt
      961 gttcaaacat cgacattgca tcttcaatat atgcagcctg tgtcatatca actcctgctt
     1021 ttttcattac ttccacagga taatcgctgt tacctgcttt taggtaagcc aagtagttct
     1081 ctagtgcctc tggttcctgg tttagtattt tcttcgccag tgctgaagca gcagaaaagc
     1141 cagtcgagta ttggaaaaca tagtaattat aataaaaatg cggtatccgt gaccattcga
     1201 atttaatttc tgggtcttct tcgactgctg gaccataata ttttgcattc aatttaccat
     1261 aactatcact taggtattca ctagtcaatg gcacaccttt ttcatcttcc gtatgcatga
     1321 aatgctcgaa ttcagcgaat tgtgtctggc ggaaaactgt tcctttaaac ccatccaagt
     1381 aatggttgag tacataagcc cgtacacgag ggtctttttc tgtttccaat aaatactccg
     1441 ttaggatatt ttcattcgtt gtcgaagcaa tttctgctaa aaagatggag tagtcgccgt
     1501 acacataagg ctggttcgaa cgagtgaaat aactatgaac actatgtccc atttcgtgga
     1561 caagcgtaaa tagctgatcc agcgtatcat gccaattcaa taaaatatat ggatttgtgt
     1621 catagcttcc cgaagaataa gcaccgcttc gtttcccttt attttcgaca acatcgatcc
     1681 aacgttcaga gaatgctttt tctacgatgg ccatgtattc ttcacccatt ggtttcagtg
     1741 cttctaaagc tttttctttt gcttcttcgt acgtaaaggt aattggagct tcccctaaga
     1801 ccggtgtata aagatcatac atgtgcagtt tttccacttc taataaacgt ttccgtaatt
     1861 ccatgtatcg atgtaacaaa ggcaaatgct tgtttaccac gtctaccaaa gtatcgtata
     1921 cactttcagg aatatgatta ttgctcaaag acgcttctct ggcagagctg taattacgga
     1981 ctttcgcttt aaaattatgt ccttttatat gtgtgcctaa agtagaagca aatgtatttc
     2041 taaattgttc gtaaacactg tacaacccct taaatgctgc ttcgcgcacc cttcgatccg
     2101 tgctttctag caactgacca tacacgccat gagataattg gactatttca ccattttctc
     2161 cttcaatcgt tggaaaaact agatctgcat tattcaaaac agcaaatgta tcacttgaag
     2221 catcaaagat ttcacctgct ccagcaagaa gagattcctg ctcagcagat aagacatggg
     2281 ctcgattatc tactatttgc tggatataat ggcgatagac ttccaatttt ggttcttctt
     2341 tgaaatattg ccaaatctgg tcatctgaca attgcaatat ttctggttca aaccaggaaa
     2401 cggcttcact aactttcgaa aacagactgc ttgctcttgc ataaagcgct tggtaatctg
     2461 tatttccagt gtcttgatcg tttttaaggt gcgcatatac ataaatgact tcagtttggc
     2521 gataaaccct caatacgaat tcaatcgcat ttaaaaattg agaagcgcct tgatcaagtg
     2581 ttcctttgtg tttttcagat tgttttaact cttctgataa ttccaaatat ttctcatcaa
     2641 actcttggtc gcttgaaaag atcttggtca agtcccaagt taaattttca ggcaattctt
     2701 ctcgttttgg caactgcttt acttccatga aatccactcc ttttcttccc ttagctctat
     2761 ctatcaaaat agatcatagt ctaacatcca catgtcacag catctaactt ttctactcat
     2821 tcatgtgtct gcttccatca attttagcat aactaaatct tgttttacat agaaaaccga
     2881 ttcctagcct atttttatac ttactatttt ttcaaagaag acaagtgtat gcattcgtta
     2941 aaaaactgct gatagaccat ctcttcatca atcataggaa aaagccattc ccttttatgt
     3001 tcttttattt ggcaaagcca tgagttgaaa tcaggaactt tctggttttc caaggcttct
     3061 tcgtacaaca ttcgataaag aaaaacctgt tcttgtaaat aaaagaaaaa ccgacttttt
     3121 tgatagatcc acgatgatag atgcaaaaga tgtttatgac gcaagtagca ttgttcttgt
     3181 atggatactg tattcttttg cttgtgaata agttggcgtg tcagccattt cttcccatct
     3241 tcactcactt tttctatttt tttcatttgg ttcattttaa tttcgttact agtgaatatt
     3301 tctttaaggt ccctactaga aaaagtccag cagctactgc aaaaggaaat atgccctgat
     3361 acagtctctg taatatgatg atacaaataa agcttttgtt tcttgagatc agctttccag
     3421 caatgcactc ctctttttct attatagtag cagcaacttt tttctatcaa tgagaattgc
     3481 gattgtccaa gaaaagaatt accaagtatc caccatactt ggtaactgtt attcaaataa
     3541 ttttgggttc tttcaataaa tctctggtga gacagtctag aacattggat ttctattgct
     3601 agattcgcca acaaaatatc cggcctttgc cgcaacctcg gcaaataggc ttccaaaaat
     3661 actggttcta ctgactgtcc cagccaatcc atgaagcatt cctttaactg taagtgctct
     3721 tttgattctc tttcactaaa gaccgaacag ttatctgatt tttgatgggc aaaatgagca
     3781 cattttttct ttcccttttt caaaatcact ctttttcgac agccacgaca ataatatttc
     3841 tttccttttt ctgcatgttt agcaaaacag cacttattat attcattcat tgcaagcagc
     3901 atttttctcc ctctgaactt atttacgtct aagaatttat ttacacgaaa aaagagggcg
     3961 tgaaaaagct attctgcatc aagtaataag aacagctaaa caaaaatagt tcccaatatt
     4021 tttcgtttgg ttgggcttgt taccgcagat gcaagctttt gaacacattt atacgaaaaa
     4081 aagactgcga cacaattttt gtcacagtct cttactataa tgctgattta tacaaaataa
     4141 aatttcgttc gctcgatagc attacgcgcc atcagacatt gtccatattc attcaatgtt
     4201 tctggtgtac gatcgctctt ttcagcaaac tccaaaattc gagcaatctg attctctaca
     4261 tccgcttggt tgagattttc catccagaag tgaacgacta ggtaatagcg ctcttcgaat
     4321 aaatacaaat cagtccaagc agactctagt tcgacatctg ttgcaagttg gatcacttgt
     4381 tcaaaatctt caaaagcaaa agttgcttgt ctttcctgtt cttctagggc gcttccagat
     4441 aattcttcct ccggatcgct gccaataatc tgctgacgaa gaaagtcact cacatcttct
     4501 gaatcaacag tagaatcttc tgattgagaa atttcttcat ccggaagatt tttactgata
     4561 aacagttcta atccgtctcc ttttggcaaa acttggaaag tgacagcttc gcttcctcgg
     4621 aactcctctt cgatatcaac ttcttccaaa atactataaa agaaattttc gatttctttg
     4681 tgattgccaa gtaaatccaa aaatgaaacg ccccgttcct ctaaatcttc atgaccaatt
     4741 agtacacgga tcgtattttc attaatatgt tccatttcca ttttgctaca cctcactttg
     4801 ccacaatgtt taatatagat tcattgtagc gaaatcagct taaatgtaaa gaaaaaaaat
     4861 ctcgctgtta agcgaattta ataaaaccag cggatttttc aacctttcaa gctatcttat
     4921 ttaactataa catttttggc agacgaatac tatatagccg acttttcagc taattttccc
     4981 tctctatttt tcgtgcaatc atcatcttct actacctttt tatacatcta atcaagaata
     5041 ctttttgtaa aaacaaaaaa acttggaaaa actatctttg taatagtctt ttccaagttt
     5101 cgtattatcc ttctataatc cagccatcaa ttgtgcttga cgtaattcta attgtcgtac
     5161 atcgcgcggt aggaaccgac gaatttcatc ttcattaaaa ccaacttgca gacgtttatc
     5221 atcaatcatg attggacggc gaagcaatcc aggattgttt tgcacaagtt ccaataattc
     5281 ttgtaacggc agatcatcta aatccatgtt cagtttttgg aatactttgg aacgtgtcga
     5341 gatgatttct tctgttccgt cttctgtcat ttgtaaaatc gcttttaatt cagaactgtt
     5401 caatggttct gaaaaaatat tacgttcaac aaatggaatc tgatgttctt gcaaccacgc
     5461 acgagccttt ctgcaggaag tacaacttgg ggaagtatat aatgttaaca acgtgcacca
     5521 ctccttttcg tgataagaat cacttttttg taacagaaga tcataataat ctcccatctg
     5581 tttctattat acataatcaa cttttaaata gctacctttt tttcataatt tttttaaaaa
     5641 aatgaaagtt atctaaggtt aatatacagt aaaaccagca ttctcgcttt ttttatcatt
     5701 taaaaatta
//
LOCUS       DAZKPE010000119         5324 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000119 DAZKPE010000000
VERSION     DAZKPE010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.121"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(45..1022)
                     /locus_tag="ACG930_002777"
     CDS             complement(45..1022)
                     /locus_tag="ACG930_002777"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFQ0519890.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            complement(1025..2134)
                     /gene="pdhA"
                     /locus_tag="ACG930_002778"
     CDS             complement(1025..2134)
                     /gene="pdhA"
                     /locus_tag="ACG930_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFQ0519891.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            2296..2553
                     /locus_tag="ACG930_002779"
     CDS             2296..2553
                     /locus_tag="ACG930_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519892.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            complement(2595..4019)
                     /locus_tag="ACG930_002780"
     CDS             complement(2595..4019)
                     /locus_tag="ACG930_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFQ0519893.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(4283..5260)
                     /gene="guaC"
                     /locus_tag="ACG930_002781"
     CDS             complement(4283..5260)
                     /gene="guaC"
                     /locus_tag="ACG930_002781"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFQ0519894.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         1467 a         1140 c          912 g         1805 t
ORIGIN      
        1 aatttaaatt gataagccat gactttgttt cgtcccttct tttcttaaaa ttccgcgatt
       61 tcttttactt tgtcttcgat atcttttgca tttggcaacc agacattttc tgcttgtcca
      121 aatgggaaga ctgtatcagg tgcagaaact cgtccgattg gggcttctaa tgaaaggata
      181 gcgcgttctg agatctcaga aactacttgc gcggcaacgc ccgcttgtcg ttgtgcttct
      241 tggacaacaa ctacgcgacc agttttttcc acggattgaa tgatcgtttc tacatctaat
      301 ggcgcaactg tacgaagatc aatgatttca acagatatat tttcttttgc aagattgtct
      361 gctgctttga ttgcttcacg caccattgct ccgtatgtga taatagatac atctgttccc
      421 tcacgagtaa ctgctgcttt atccaaagga acttcgtaag cttcatccgg cacttcttct
      481 cggaatgagc gatatagttt catgtgttct aggaaaacaa ccggatcgtt acttctaata
      541 gaagaaatca atagtccttt tgcatcataa gggttggaag gaatcactac tcgaatacca
      601 ggagactgag cgatcaaacc ttctaaatta tccgaatgca attctggtgt atgaacaccg
      661 ccaccaaatg gcgaacgaat tgtgatgggt agatttctag tgccgctcat tcgatatctt
      721 gtacgagcca tttgagctac tacttcgtcc attgcttcga aaataaaacc aaagaattgg
      781 atttcaggaa ctggacgaaa tccttctaac gcaagaccga aactcaatcc tgcgattcca
      841 gattcagcta aaggagtatc gaatactcgg tcttctccga acttttcctg caatccttca
      901 gttgcccgga aaactcctcc gtttttccca acatcttcac caaaaacaac gacattctcg
      961 tcattttcta gttcaagtgc taaggcatct gtgattgctt ggatcattgt tttttgtgcc
     1021 atgattattt cgactccttc gcttcataaa ttgcaatttg ttctttgatt gattgtggag
     1081 atacttcgaa catgtttttc aagaaatctg aaaccttttg ttttggtact ttgtcggctt
     1141 cagcaatagc tgctttgatt tcttctttag ttgcttcgat gacttgttct tctttttctt
     1201 cagaccaaag tcctttttcc gtcaaatatt tacggaagcg gatcaatgga tcttttttct
     1261 gccaatcgtc atctgtgtct tttgtacggt agcgggttgg atcgtcacca gatagtgtat
     1321 gtggtccata acgataagtc agtgtttcga ttaggactgg tccatttcca ctgatcgccc
     1381 attcccgtgc cattttagat acagtatata ctgcaagcgg atccattcca tcgacttgaa
     1441 taccaggaat cccagctgcg acagcttttt gtgcaagtgt ttttgctgca gtttgttttt
     1501 cacgaggtgt agagatcgca tacccgttgt tttggatata aaatacggca tttgcatggt
     1561 aagcgccagc gaaattgatt gcttcgtaaa aatcaccttg tgatgaaccg ccatcaccag
     1621 tataagtgaa gacgacattt ttcttgtttc gtttcttcaa acctaatgca acaccggctg
     1681 cttgtacata ttgtgcaccg atgataattt gtggtggtag agctttcaat tcttccggat
     1741 aagaattacc tgcagcatgt cctcgagacc ataaaaaagc ttgagataaa ggtaaaccat
     1801 gttttactag ttgaggtaca tcccgataac ctggaagaag aacatcttct ttatcaaatg
     1861 cgtaagcact agccagctga cttgcctctt gtccagcagt tggtgcaaaa aagcctaggc
     1921 gtccttggcg gttcagcgct gttgaacgtt ggtctaatac acgagaccat accatatgag
     1981 tcattaattc aacgagttca tcatcggata aatcaggtac taaatctttg ttaactacgt
     2041 ttccatcttg atcaagtgct tgatatactg ggaaatctgc attgacttca tctagcagtg
     2101 cttggaagtc gatcggtgct tttttgtttg ccatttgtca cacattcctc tctcatctat
     2161 aagaaaatct cttcattctg cgattgaaac agtgaataaa actgtatcac tatttaaccg
     2221 tcttcattaa taaattatca tggatttatg agaaatacaa gctaaaagca caaattttca
     2281 cgatgaaagg aaattatgcc aatccgcata ttaacagcat tagtgaataa aatcacaata
     2341 aggaaagcgt tttatatttc atctgcattt tttctatttt ctaatcaaac ttacaaccat
     2401 ctgtttctat ttaaaaacgt tggtgttata cagttttgtt gcaaacattt attttattta
     2461 cacatcgtga acggacgtac aaataatggt tttttcttag tttctttata tcgtattctt
     2521 tttccgaaaa aaaagaaaca gcttgaaatt taaatccaag ctgttatatt ctttaatcta
     2581 tttactttgt gaaattattc tgttaaccac ttttctagaa ttttcatctt tgaataaaac
     2641 aacggtattt ggttttcatc cagcctactg taattgattc tgattccatt tatatcttgc
     2701 ccaaaaagta gacttggtgc aattccaaga cccatatcta ctactttttc tgctagttcg
     2761 gggtctagtt ttttcccatc ccaagtaatc caggcatagt aaccacctaa aattgaatga
     2821 agcttgaaaa acgattgtga atctccccaa gcgcttatca gtcggctttt ttctttcaac
     2881 ttttttctta catcttgcat tttcaaatca attgcttcat taaatacatt agccactgtg
     2941 atttgtgtaa ggatattcat cgaaaactcc atcatttctt gcgcttgagc tagttgcgag
     3001 ataaaagtct caggtcctat cacccaaccg attttcgttg tttttcctaa aaccctagat
     3061 aacgaaccga cgtataacac attatccgga tcaatcgttc gtataggaag gacttcttct
     3121 tggtttagaa atgaaagatc cgtaaataca tcgtcttcaa taattggaag ccgatactgt
     3181 cgacacaatt ctactagctt ttctcgtcgt ttttgactca tcacttttcc tgtagggttt
     3241 tgaaaattcg ggttgataag cactgctttc aatttatttt tatggatcga ttctttcagt
     3301 ttttctaagt cgatcccttc ttcatccatc ggtatcccaa ataaacgcgt tcctgaagct
     3361 ttgaaaagag gtaatcggta aaaaaaagaa ggtgactcta cagctatccc ctctccagct
     3421 gaaagaatcg tttgtaaaat caaaaagatt gcttgctgac cgccaccagt cacaagaagc
     3481 tggttggggg aaaatgccaa ttcaaattta ctttccaaat accgtttgat tttgttacgt
     3541 aacggagtat agcctaaaag atccatttct ttttcttccg ctaagatttc ttcaagagaa
     3601 taagaaggaa actcaaaatt cggcaaaagc tcatctggca tctcgctagc gtataaatca
     3661 agaaacgatg ttttttggat ctgctttgct tctcttattt tttgctcata ccagtccgtc
     3721 tgctcataac gaggagagat catttgccgc caatcgattc ttggaacagc gaatttcccc
     3781 cattcagtct gattaacaaa ccatccgctg ccacgtttgc tcgttagtac cccaagctcc
     3841 ctaagctctt ccaatgcatg gacaacggtg gaacgattca caccaaaaag ttgccctagt
     3901 tttcgttctg attcaagttg acttccagga ttgatccttc cgttttcgat ttctctcata
     3961 atctgttcca taatttgacg ataaatcggt ccttgttttt tctctacttt ttcccacata
     4021 agcttctctt ttctattgtc tattttttct tttgatttta ccgaatttac gagaaaaaag
     4081 aaaaactttt tttgcaaaac ataagggact gtgacaaaaa tcttatcaca gtcccttatt
     4141 ctgaataatg atgttcaaaa gcttgtatct gcgataataa ttccagccaa acaaaacata
     4201 taaagaacta tttttgtttg gctgttctta ttacttaatg caggacaact ttttcacaac
     4261 atcctaatat tttatttatt ttttagattg tgtctccatt aaaaatcgaa tttttcacga
     4321 tgacatagtc aacttttcga atggcttcca gatctcttcc tccagcataa gaaatagatg
     4381 attgaaggtc ttgttgcatt tccactagtg tatctttcaa agatcctttg tgttggatcc
     4441 agattttctt tccttcaaca tttcgttttt cgcctttttg gaattctgaa gcagaaccaa
     4501 agtattcttt atacacgatt ccattttcga cttttgtttc gccaggagat tcctcgtgac
     4561 cggcaaacaa tgaaccaatc atgaccattg tcgcaccaaa acggacagat tttgcaatat
     4621 cgccatgtgt tctgatccca ccgtcagcga tgatcggctt gcgagctgct ttcgcacacc
     4681 atctaagagc tgccagttgc cagcctccag tcccaaagcc tgtcttgatt tttgtaatac
     4741 atacttttcc tggaccaatc ccgacttttg ttgcatctgc gcccgcattt tccaattcac
     4801 ggacggcttc cggtgtacca acattaccgg caatcacaaa agtttcaggc aaatattttt
     4861 taatatgctg aatcatatca ataactgagt tagcatgtcc atgcgcgatg tcgatagtga
     4921 tataatcagg atttagcgat tcttctgcca acttctctat aaaggaatat tcctctttct
     4981 tgacgccaac actgatcgag gtaatcaatc cacgcttttt catttttttg ataaacggaa
     5041 ttcgagctgc ttcatcaaac cgatgcatga tatagaaata accattttcc gctaagaatt
     5101 ctgcgattgt ttcatcaata atcgtctgca tgttggcagg cactactggc attttgaatg
     5161 tatgtttacc taatgtgacc gttgtatcac attcagaacg gctatttacg atacatttat
     5221 taggaattaa ttgaatatct tcgtaatcaa atactttcat tacattatcc tcctgatgtt
     5281 cacatccagc aaaacacgaa cattattaat ttaatcaagg cttt
//
LOCUS       DAZKPE010000120         5272 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000120 DAZKPE010000000
VERSION     DAZKPE010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.122"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            125..1000
                     /locus_tag="ACG930_002782"
     CDS             125..1000
                     /locus_tag="ACG930_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0519895.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1104..1868
                     /locus_tag="ACG930_002783"
     CDS             1104..1868
                     /locus_tag="ACG930_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFQ0519896.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            1855..3297
                     /locus_tag="ACG930_002784"
     CDS             1855..3297
                     /locus_tag="ACG930_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0519897.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3308..4639
                     /locus_tag="ACG930_002785"
     CDS             3308..4639
                     /locus_tag="ACG930_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HFQ0519898.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            4652..5110
                     /locus_tag="ACG930_002786"
     CDS             4652..5110
                     /locus_tag="ACG930_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0519899.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
BASE COUNT         1781 a          764 c         1109 g         1618 t
ORIGIN      
        1 ttatgtgtta aactattttt gtaaattatg tagggtgcta ctattcaatt aggcacgacc
       61 taagaaaggg ttctttctta ggtcgttttt tgtctttaaa aattgtttgg agacaaaaat
      121 atgtatgaag gagtctgcaa gttgttttgt tttatcatat agaggaggtg aattaacggt
      181 gtatgtgatg aaaaagctga atcataatgc tgtattgatc gatgacgatg gaatagaaaa
      241 aattgcgatg gggaaaggga ttggcttttc tgctaaagtg agtaagccat ttgatgttga
      301 ggatgctgac aaattatttg tattagattc taaagaaaag atcaaacgat tcagtgagat
      361 agtctcgcag attccaatcg aatttatgga ttttgcggaa gaagtgattg aactgataac
      421 agctaggatc tcctctccat tagattcaaa tatctatatt acattgacag atcatattta
      481 ttttgctatt caacgaaaaa gagaagatag agatgtcaca gcaattatgt tgccagaaat
      541 gagattcctt tatccaaatg aatatgatat agcagtagaa gtggtcgagc gaatcaatca
      601 tcgatatcaa accgagttag ggtcaaatga agtaggattc atcactatgc atatcattaa
      661 tgctgagcta ggagagccta atagtttaaa gagcttaaaa atagtagaaa tgacgaccac
      721 gattttgtcc catctagaaa aatcctattc aaacgtttat gataaagaat cactgactta
      781 tcatcgctta atggttcata tcaaattcct ggttaaacgc ttgatttatc aggaagaaac
      841 gccagtagaa aatattggtt tttttactga aacatttaaa catagcaaag cgtattgtac
      901 agcactaaag attaaagata tcatcgaaca gcaatttcaa cttgccattc aagaaaatga
      961 aatcatctat ttggcaattc atctagcaag aatctattaa aataagggcg taactatcta
     1021 taggcgcaac caaatgacac atagtaaatg gactatgatt atttggttgc gcctatttta
     1081 gtagaaaaaa gaaggagaat gaaatgggaa aagtgatttt taattcggat gattttggct
     1141 atagccatgg tgtgaattat gggattatgg atgcttatca gcgaggaatt ttgacatcaa
     1201 ctacattgat ggcaaatatg ccgggtttcg agcatgctgt gaaactaaga aaggaaatgc
     1261 ctaggctagg tgtaggagtc catttaacat tgacgtgtgg caaaccactc ctcaaaactg
     1321 tcgatactct tatcgaaagc ggagagttca gatccttatc ttattatcag catccattta
     1381 acattgacaa agatcaactg tatcaggaat ggaatgctca gattcaaaaa atttatcatg
     1441 cggggatcat accaactcat ttagacagtc atcatcatac tcatactttg gatgaaaatc
     1501 aggaggtagt tgttacatta gcaaaaaaat atgatttgcc ggttcggagc aactttgaac
     1561 gaaaagatga agttcgtcat gtcgattatt ttgagccttg tttcgatgtc gtaggagaaa
     1621 ctgatgaaaa aaaacgacaa atcaatacga gtgtggaaga atatttggca agtttactca
     1681 tgatattgag agaagataaa acgatcgaag tcatgtgtca cgcagcgtat ttggatcagg
     1741 aattgttaaa tggttcaagt tttgtgtatc ctcgtaccca ccaagtcgaa tttttaattc
     1801 attcagcatt tgctcaaaaa gtgaaaaatg atcctttgat tgagttagta acatatgagg
     1861 atatttaata gaggaggaat aaaaatgaat gttaaatcaa atgtgcagaa gcttggaaga
     1921 gcgatgctac ttccagttgc agcgatgcca ttagcgggat tgatcatgcg tttatcagct
     1981 gacgatatgc tgaacatccc agtaattggt gcagctggaa atgccgtttt tggaaacttg
     2041 gatatcttat ttgctatagg agttgcaatc ggttttgtca aaaataagga caaaggaata
     2101 cctgcactta ctggtttttt agcgattgct accttgaaaa aaggcttaga aattatggac
     2161 ccagaagtga atatggggat ttttggtgga attatttccg gtttagtagc ggcatggacg
     2221 tataatcgct ttaaagaaca aaaattacca gtagtttttt cttattttgc gggcgaaaaa
     2281 ttcccattga ctatggtgat gattctacaa acaatcgcag ctgttttttt gggctttatc
     2341 tggccgctca tccaaattgg gattgataat tttgcaaaac tgctcgttga tatgggagca
     2401 ttaggtgtgg ggatatttat gtttttgaat cgtttgctga tcccctttgg actgcaccat
     2461 gtgttgaata cgtatattta ttacgattta ggaagctata catctcctag caaggaagtt
     2521 ttcagaggag agatgacacg ctttatcaac ggagatcctc aggctggact gtttttatca
     2581 ggtttttttg tagtaatgat gtttggtata ccagctatat gtctagctat ctataaagca
     2641 gcttataaag aaaataaaga gatggtcaaa ggaatcatgg gaagcggtgc aggaacttca
     2701 tttattgcaa atatcactga gcctgttgaa tttagtttca tgtttctttc tcctatgttg
     2761 tacgtgatcc atgcactttt tgccggttta gcagggattg tctgttactt attcaatata
     2821 cgaattggtt ttacattcgg agcatgtatt gttgattatc tcatcaattt tcgaatcgct
     2881 accaatgcta ttttgattct tccaatcgga attttctttt ttgccttgta ttacgttact
     2941 ttttattatt tgatcaataa gagaaacatt cagacattag gacgtgaagc taaggcagag
     3001 tttggcaatg aagtaacctt agaagaaaca gagttagggt tagcaagtaa aaattatgaa
     3061 tatatggcaa caaaaatgct acaagcgttt ggaggaaaag ccaatatcct ggatgtctat
     3121 agttgtaata cacgcctacg ggtagaggta gtggatccca ccatggtcga ggaacagcga
     3181 atcaagcaat tagggataag cgggatcatt aaaccaactg aaaaaaatta tcaaattatc
     3241 atcggcttag aagtgactta tgttatggca gaattcaata aattattaga agaatagaaa
     3301 ggaaaagatg atgatgaaaa aacagattat cactatagct ggaggcggga gtacgtatac
     3361 accaggaatc gttcaagcca ttttgaacaa tgaaaaacgg ttgccattat ctgaaatacg
     3421 tttatatgat attgatgaag aaagaaatat ggatatgtac ttgattgtta aatttatgct
     3481 gaaaagaaaa ggtttttcaa atattcgcat tcgtgcaacg gatgatccaa agcttgcttt
     3541 tacaggatgc gattttgttt tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa
     3601 ggacgaaaag attccactta aacatggatt agtaggacaa gaaacgtgtg gactcggagg
     3661 atttgcttat gggatgcgct caatcaaagg tttattggaa attgtcgatc atatacaaga
     3721 ctatgccccc aaagcatgga ttttgaatta tacaaatcca gagtcgatcg tttctgaagc
     3781 tgttcgtcgt aaatatccga atgtaaaaat gattaatgcc tgtgatatga ctatttcaat
     3841 tgaagaaacg attgcagtga attacggtta tgatcgtaag aattggatcg ttacgtatta
     3901 tggtttaaac cactttggct ggtatacatc gatttatgat aaagaattgc aacgagaaat
     3961 tatgccagag attattgaaa aactaataac aaaagaaatg caagtcgccg attttaatat
     4021 aggagataaa acttggcaaa aaacctttca aatgatgtca gtcatcacga aaaattttcc
     4081 aagtaatatc ccgaataatt acttagagta ttacttatat cctgatatgg tcgttgagca
     4141 tactgacaaa gagtatacac gtgctaatat ggtcatggat ggacgagaga aaaataccaa
     4201 agaaatggct gataaaatac gccgcggtat tgtggaagaa gtattgaact ttaattttgg
     4261 ggagcatgga caatatatcg tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg
     4321 ctttatgcta atcgttccta atcaaggggc gattccgaat ctacggtcag atgcagttgt
     4381 tgaaataccg gcatatgttg gtgcaactgg tgtggagcca attacactaa gaaaaccaat
     4441 cagtgatttt cataaaggat tgatggaggc acaagttgca gtagagaagt tactagtaga
     4501 tgcttacttt gaaggttctt atcaaaaagc tttacaagca tttacattga atcaaaccgt
     4561 accaaatgcc agagtcgcaa aaaaaatact agatgaaatg atcaaagtaa acaaaaaata
     4621 ttggccagca ttaaagtaga ggtgataaaa agtgcatttc tttaaaacaa gaaacattct
     4681 aaaagctgta gctagtggtc aaattattcc attaacagca gtaaaagacg aggtcttttc
     4741 ttcaaaaatg ataggagttg gatacgctat aacgaatcat gatggatata tccatgcgcc
     4801 agttaaagga ataatcgata atatatttcc tacccgacat gccataacga tcgaaagtga
     4861 atctggcaga aaaatactga tccatatggg tttagataca gttgaactcg aaggaagtcc
     4921 gtttcagata cgggttgaaa gtaaccagga ggtaaaagaa gggacactgt tagctattat
     4981 agatttgaag aagttggagc aagcacaaaa agatacggtg atcattgtag tttctccagg
     5041 catttttgaa ggaaatttat taaaacaaaa ccaagaagta aagattaaag atagttgttt
     5101 tgaattttag tgtacgatga aaaaagttaa atagggtgat atttatgggt gaatttacaa
     5161 aatttttttg aaatgatatg tttcaatcac tagatttaat cattttgatt tttgttaatt
     5221 atcgaatttt tttgttgctc ctatgattta gaaaacttat tttcaggatt ct
//
LOCUS       DAZKPE010000121         5269 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000121 DAZKPE010000000
VERSION     DAZKPE010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.123"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..266)
                     /gene="prgO"
                     /locus_tag="ACG930_002787"
     CDS             complement(<1..266)
                     /gene="prgO"
                     /locus_tag="ACG930_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFQ0519900.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRS"
     gene            complement(238..1191)
                     /locus_tag="ACG930_002788"
     CDS             complement(238..1191)
                     /locus_tag="ACG930_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0519901.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1803..3296
                     /locus_tag="ACG930_002789"
     CDS             1803..3296
                     /locus_tag="ACG930_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFQ0519902.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3431..3727
                     /locus_tag="ACG930_002790"
     CDS             3431..3727
                     /locus_tag="ACG930_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFQ0519903.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3828..4679
                     /locus_tag="ACG930_002791"
     CDS             3828..4679
                     /locus_tag="ACG930_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519904.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4700..4912
                     /locus_tag="ACG930_002792"
     CDS             4700..4912
                     /locus_tag="ACG930_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519905.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         1800 a          820 c          998 g         1651 t
ORIGIN      
        1 gatcgtctat tatatataat ccgttcctcg tcgtttaaag tatcaacata ggcgtccatt
       61 gcaagtttga ctatttcata cataggaata tcttttgcat aactaagatc ccgaatggtt
      121 tttagtacgg gaggatctac ttgaactggt tttctttctt tcgcagtgta ctttcgttcc
      181 cctaactcga cattaatatc atctttaatt gaaatatctt cagcaccaat tttcttctta
      241 tctttgttcg ttggtaataa tgccatttag tttaatctcc tttccaagag gtaggatatg
      301 attggccatt gagtcagcat atttaggtgt ataatcaaat ccttcaatat caccatgttg
      361 ttcatagtat tcaattcttt cttctaattc tgtaaagatg tctgcaaaaa tagcccacca
      421 tcttcgatct acataatcat ttaattggat accattctca ccatacattt ctaaccgatc
      481 cgagccttta acaatgcttt taaaaatgtt tgattcacca tacttatcaa ttgttttttg
      541 atagtttgcg tgttgagagg aacgtcgcac tgagaaaaga acaggcaaaa ttccaatgat
      601 ttgaagatga gactcttcaa aattcgtgac aatcggaact aaaactttat taataaaatc
      661 ttctgttcct tccattgcgt accgttttaa ttcttgcatt gcaataatat aatctgcagc
      721 agttaagaat gcacgaacca cattatctgt tgatggtggg cagtcgataa agatataatc
      781 gaaatttttt ctcaattctt ctaaaggttt aatgaaggcc aatgatctct tacgacgatc
      841 aggatatttt tcggacaagt attcattaag ttcttcagat ccaggagagc cagccataat
      901 atataaatgt ggacttactt gagtaatacc tgaaacccag tccccttttt tgattgctgc
      961 agacatggat cgatcaaagc tagtaatttg atacgttgat ccaatgttgg aagtagtatt
     1021 tctttgttgg tcataatcaa ttagcaacac gtctttttca aaaagttgac tagaaacaat
     1081 cgctaataaa tcattgtctg tagtcttacc aatgccgcct tttctacctg taagcattac
     1141 aacttttcct agtttatctg atgttttaaa tgcagtccgt aagttttcca tagttccctc
     1201 caatttccta tactaaatat atttagtata cttcatatac ttaatatatt cgatatatct
     1261 aatatactcc aaattgataa gaattcagac tttataagga atatagtgga tatactaaat
     1321 atatttgcta tattcagtat atcagatata ttcaaaatgt caaaatatat ttgtgcgttt
     1381 tgcgttgaca atttagagtg aaaagaggta aacttaattc tatagaaacc acagataatt
     1441 cactatttac aaagtagcaa aagcagtggt actctttaaa cagaaaaatt acataaaaaa
     1501 aagagacgga aataattgat tttagcagaa tcaattattt ctgaatcaca tggttaggac
     1561 atgtgttcac gctcgtctca agaatatgta agtagctacc aactacttat attaaaagtt
     1621 gatcggatac cttttccgat tgcctttatt ctaccaaaaa aaggcgagca actcaacaga
     1681 agaacgttta tttagtgtac ttaaattaaa tattcttaaa cactgaagag agaacacata
     1741 ctatggctga gattaaagct aaactgtgtt ctctttttgt ttgagaaagg acgttacaat
     1801 cgatgttgag cgaaatttat tcagctattc ttaaaaacgg cttacgtaca tacaaatatc
     1861 gaaacagcac catgaaacct gcaggtcata ttgattccag taggagtggt gctatctttg
     1921 cgtaccgtag caagcaatta atgaatgttg ggcgtggtat ggtcattact tcggaagaag
     1981 ctattttaga gaacgaaaag aaactaacgc attggacacc taatacctat cgctttggta
     2041 cttatgcgga tgattatcga acagtggtta aaggtcattc tgagaaaaac ttaagtcaaa
     2101 tcaacacatt tgtagttgat atcgattcaa aagagaacca tcaaggcgaa attattttag
     2161 cctgtttaga tcaagtgggc tacatgccaa cgctaatttt agaatcagat catggttatc
     2221 aagtttattt tgtactaaag acaccaggct atgtcacaaa gaaaagcaat ttcaaggtga
     2281 tcgatgtagc aaaaaaaatt tcaaaaacaa ttcgtctaca gttggctgaa aaattgtccg
     2341 gagtggatct aggatgtaac cacttcggaa ttgctcgatt cccacaagaa aataatattg
     2401 tttttaaaga aatgaactat cagtattctt ttgctgactg gattcaatgg tcgatgaagc
     2461 ttgaatcaga tcaaaaaaca aaagaagatc gagaacgaaa actaattgtc tttcctgaga
     2521 aaaaagaaat tcgtcaagta gatgaaccgt ggttcgatat gttacttcat aaagcaaaca
     2581 tcgtcggcgg agaaggacgt cttggtcgaa ataatgtgat tttcacgctt tctttagctt
     2641 attactcttc aggttatgca ttggatactt gcgaatacaa tatgttcaca ttcaacgaac
     2701 ggttacagga accgctatct gaagcagaat tagtaaagat tgtacgtagt gcttattctg
     2761 gtaattatca agcagcaagc agagaattca ttattgaatt gtgccagcaa tgggtttcac
     2821 caaccttaaa aaataatgat ctgttcattc aacgacgtgg ctggtggaaa tttaaaaagc
     2881 cacgagatca aagaaaatat agtcataaaa atgaatggaa agaagatcta ttggcttatc
     2941 taagcgaaaa aagtcttgct agtgagcctt atttgaacct gtcaaaaaaa gaattggctt
     3001 cacaactaac gatgcccaag cgaacacttg ataagatctt aaatgagtta cgagaggaga
     3061 ataaagtctt ctacaaggta acacgaggaa gaaatggcgg aatgatcatt gcttcagtca
     3121 aaacgttgtt cgcgagggtt attcaactaa gtaaagaaaa gagactagat tattcaacaa
     3181 ggatcacaga ggtatttgga ctcaacgaga gcttagtaga agagacattt agacaattat
     3241 caaccccctt gaaccctctt aaagaagtga atctttttga agtagataca ggttgaaaaa
     3301 taaaaggtgc aaattgccct atacaatata tctatgatac ttctgtaggt gttgctccct
     3361 ttgcctagct acgtgtaggt ggtatactta taactgcgta tgcagtctta tgtatcatgg
     3421 aggaagttgt atgtcgttaa aaaattatgt ctattcacat cctgttaatg tgtttatcat
     3481 tggtcgtttg ggattatctg tggaagtgtt ctgtgagctt tatggtttta agcaggggac
     3541 tttgtcttct tgggttacca gggaaaaaac agttgcttct ttgccgattg agtttcttca
     3601 tgggttgtcc ttagcttctg gggagactat ggatcaggta tatgattgtt tgtgtgtgtt
     3661 agagcaggag tatattgagt ataaaatagc taacgagtta agaaaaagga agaagtatat
     3721 ccagtagtag tttttattta cttaaaaaat tggttcattg agcaacctat cgctgctaaa
     3781 gtagcaaagg aaaacgttaa aggaaagaat ttagggaaga aatcgaaatg aaatcggacg
     3841 actggattga acacacctgg cttcctctga aaagaaatag caaacgaaag aaattttggg
     3901 tattgcaatt atggccatta ggaaaacttt gtagttacgg ggcacgactt attcttgatt
     3961 taaccgttta ctcgattgga gtatttggaa cggcttatta cttgataaat gatcccaata
     4021 ggattgcagc atcagacatt tttacagtgc taatgacgtt gatttttgtc atgctattgt
     4081 ctatttttac tcaattagtc atgcaattta ccaggcaaaa attaacagca ggaaaacttt
     4141 tcaaaagcct attcgattta attgttgtaa atgcaattct agcgacttta ataaaacaaa
     4201 ttgaacaatc tggaagaaca acaaaaggag tgaaggattt tttattgacg tttattcact
     4261 ttgtaaatgg acacatgtat ttgtttgaag tgggtattat tctctttttt gtcgggtatg
     4321 tatccacgaa acttattaaa cgttcaattg aaaaagaaat tgaaattgac ctgattccga
     4381 cacttcttgg ttatgagtac aatgttgatt ttggaagata tgacgaattg atcaatacgg
     4441 atatcgttca cacgagtatc catgaatcta ctgttaaggg catcagatct attttaaaaa
     4501 atggccagga aatgaaagca atagatcgaa gaaaagagat ctacaatttt tatgaagtcg
     4561 aagcaagcct acgatatggc atcggaaaat tgtggttaga tggaagtaat attcgtcaaa
     4621 acaaaccata cattttttgg aacagtagtg atttagaact tccaatgaaa gataaataat
     4681 tatggagaat cgtttgaaaa tgattcctct atacaggatt gtgcttatag ttggcatgga
     4741 gttaaaaacc ttaaagaagg agcagttatt caaagtgaaa gaacgtcata atcagttact
     4801 atgtagtaaa acgggtacga tgaacattga ataccgaaca gaatatttag aattaacgaa
     4861 tcaaactgat tttttgttga ttcgaaagca acaagagcaa gaaaaaaatt aatggctact
     4921 tatagccaat tgattgatga atgggaacaa ttcaaggaat ctaaaattcc agaacgtctc
     4981 taaaagcctt tatttgtaaa gagcataagg aaacgtggga acacttttta aaaaaagtgt
     5041 tccaataggc tgtgcctatt acgtttctca aaaataaatg tgggaacaaa atatttaaaa
     5101 ataggatagt gaaaggatag tgaaggatag taaaaggagg gtagtaggat agcaaaaagg
     5161 ataggctcct tttcgctatc ctttttaaat tggaggaatt aatatggaag taagaataag
     5221 aaatgtggat gagaaaatcg taagagaaat tgatcgaaga tgtgacgaa
//
LOCUS       DAZKPE010000122         5154 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000122 DAZKPE010000000
VERSION     DAZKPE010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.124"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..367)
                     /locus_tag="ACG930_002793"
     CDS             complement(<1..367)
                     /locus_tag="ACG930_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFQ0519906.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSY"
     gene            complement(364..606)
                     /locus_tag="ACG930_002794"
     CDS             complement(364..606)
                     /locus_tag="ACG930_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HFQ0519907.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            complement(1152..1682)
                     /locus_tag="ACG930_002795"
     CDS             complement(1152..1682)
                     /locus_tag="ACG930_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFQ0519908.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1864..2520)
                     /locus_tag="ACG930_002796"
     CDS             complement(1864..2520)
                     /locus_tag="ACG930_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HFQ0519909.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(2625..3120)
                     /gene="dfrF"
                     /locus_tag="ACG930_002797"
                     /pseudo
     CDS             complement(2625..3120)
                     /gene="dfrF"
                     /locus_tag="ACG930_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
     gene            complement(3518..3757)
                     /locus_tag="ACG930_002798"
                     /pseudo
     CDS             complement(3518..3757)
                     /locus_tag="ACG930_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
     gene            complement(3788..5002)
                     /locus_tag="ACG930_002799"
     CDS             complement(3788..5002)
                     /locus_tag="ACG930_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFQ0519910.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1587 a         1087 c          732 g         1748 t
ORIGIN      
        1 tatacgatgt actaggaata atttcttcat aaatcttgcc ataagtttca tatattttat
       61 ccatagcacc aatatgctcc acaaccaaat atttataaga cggtatttct ttatacagaa
      121 agccctctgg ggtaatggtt ctttggggaa tagaacagaa ataataaagt tttccatttc
      181 ttctttccat aaaagcatat tttacccaat ttcctgattg tgaaagatac gcttttttca
      241 aactactgtt aaactttctc caaaactgtg tactaatctg aatattcttt ttttgataat
      301 tagtcagttc tacttcctgc ccaataactg caaatgcgtt taattccttt atagaaaaat
      361 ttatcatttt accttgtgag cagtgataac ggtataactg tacgcattta ccgttataat
      421 acaattatca atcgttatat accagttttt tccttttctt gtgatttccg cattagaaag
      481 gctaattttt tctttgcacc attcaattac attttctaca ttcaaagata agttcttttt
      541 aattctaata acgccaagtt cagttgtgtg aagtcttcct aagttttcca gtaattcatt
      601 ttccatattt tgatacctca tttttcagca aatttatttg tatgttttat accccaatta
      661 taacattctc atatcagcac tacaataaaa ataattaagc accaataatc ttattgaaca
      721 tctccaaccg taaatctttc acaccatcag tgataaacac tgagctgaca gcaattacga
      781 caactaccat aattgcctgc acttaaattt ctgcaaaaga aaacgacaat caatttctta
      841 ttttttgaaa tcaactgtct ttctcatatt tactattcaa ttttcatagt gatataggta
      901 caatttatat cactactgta aaaatggggt tttgccttat aaatacagcg ttttccgctt
      961 gttagtgtat agtgtttctt gttttttgtg ccccccttgt tagataacgg gggctttgaa
     1021 cggctcgcaa gctcgccgaa ccgccgaagc gaaccgcccc cttgcaagca tggcggaaaa
     1081 atcttaagga ttttcccgcc aacgtggtcg gatcgctccg tcggtttaac agcttttctg
     1141 tttctctcta gttatctacg catataaatc aaatcggtta ttccgttata agtctgtgtt
     1201 ttacaaagcc ttaactttat ttccctgtct atgttgccca aaagacgaac cccatttcct
     1261 aacagagtag gaataacaga aatgtaatat ttatcaatca tatttttgct taccaactgc
     1321 tgaacaagat ttgctccgcc acaaatccaa atatcctttc ctgcttcttg ttttagccgt
     1381 tccaataata aaacaggatt ttcacttgta aaatgaattt gttgggaaga attgcactct
     1441 ttatgtgtta atacataagt tgtaaattta ttatataccc attcttgcgg agaaagttca
     1501 gtaacaacct gatgagaagt attccacccc attaagacag tatctatatc tttggtaaat
     1561 tctgtataag tgtcgatgtt ttcattgtca tttccatgac catttagcca agctactcca
     1621 ccattaccgt ccgcaatata tccgtcaagg ctcatggcaa taaataaaac tacttttctc
     1681 attttttctc ttttataaat acaaacagga atttatttct cttttttact cataagggaa
     1741 caactgattg ctacaaataa acccattaaa atccatggaa atgctgctct tataaaatca
     1801 ctaaccatac tttattcctc cttaaattcc aatttcctta gttctacaaa ctgaaatttt
     1861 tgcctatgaa tgtatcttgt tctttatacg caaacaggct tctgtgtgca taatccaatg
     1921 tcttgaaaac ggcatttgaa ttagtccaca aatatcttta ttacaccaat aatcaatcag
     1981 ccaaattgct ttttcattgt cgtttactac attcaacgat tctaagtatc cttttctttc
     2041 tttcggtatt tttcttttca attcatcata agataaccgt tcaagcattt tctcagtgct
     2101 ttcccatact tcgaaaatat ataaatataa ttcttccaga ttaagctgtt ttgaaaagtc
     2161 tgcaatctgc tgtttcatga gttcatttcc tgttgtaatg ataggtgaat tgatacgctc
     2221 ttgataattg cctgcaaaaa atacttgttc atcttcattt atcactgtat gcacaactat
     2281 atcttcaatg cggaaaatat gccaaataga ataagcaatc gtcttactat gataaccatc
     2341 agcgtttatg aaggggattg agttaaaatc ttctctgcat aattcttctt tgaaagatac
     2401 taaggtttgt attaactgac ttcgtaaagt aagtaaagta tcaatacccc tcttataagt
     2461 atctttcttt tttatttgtg cctgcattgt tttattaagt tcagaccatt ccttattcat
     2521 attcaatcct ctctcaaatt ctgattttat cgccccatac aaactggaat ttgtcttaca
     2581 acaatttata tatgcataaa aagcaatata tttatgaaaa caccctaaat ccaaaattta
     2641 ctcaattcat tttttcctta cataaaatgt tctcgtatat ttcacttcct caccaagtgt
     2701 ttcccctatc aaaacttcaa aatcattgat atcaaattct ggaaagaatg tatctccatc
     2761 ttcaatattt aaatctactt ctgtgatata cattttatct actatttgca aagcttcctt
     2821 aaatagtcca tatccaccag atatgtatac atctcgtcct ttagccaata ataatgcatc
     2881 ttctaatgat ttaactgaaa ctaaattatc tccttgatac tctgttgtgg tggaaacaac
     2941 aatattcatt ctattaggca acggatgacc gatttcttca taagactttc gccccataat
     3001 aaccacatta cccgttgtta actctctaaa ttgcttttgt tctcccttta ttttccatgg
     3061 tatattacca ttcttgccta taacattatt ctttgacctc gcaacaatca aacctatcat
     3121 ctatttcatc ctccataata tgatgtcgta cctgtgattc catcaagtgc accacatctt
     3181 aacaaactca aaattatctc gaactaacca gctcgacaaa ttcctttttt gtcttcatct
     3241 gcattatatc atattgttat aagcattgcc atttcttttc tgcttttgaa aagttactta
     3301 tcagcctatg ttttgtaaag ggtgatattc agcatttctc acgcaacaag cccttgacaa
     3361 accatagact aataagtttt aaggtaatca agcagaaatg aaatagtctg ctgtttcacg
     3421 gcaacaaaaa agagatacca acacacttat gtagtatctc ttagtctagt agcaatattc
     3481 ttttgtttgc aagcaggtaa acatgggctg tttcttaata tctttttgtt tgggaaacac
     3541 ctttttccca tcctttcacc gttgccatct ctgctgcgca caatgccaca gggataaacc
     3601 atagcaaacc gcctaataac aagaaaaata ctaagctgaa gcctgaggtc gcgaatgtgg
     3661 gatattcata taatgaaacg accattgaga tggtcatagc caaaaagcca aagaacgtta
     3721 atttttttgc aggaattttc gttttgcttt gttgcatgaa tcttcctctt ttctatttga
     3781 atttgtttca attgagtttg ttgccaaaga agaaaaagtc caatccttct tcttgttctt
     3841 cttttgtagt agtgatcgtt gtaaagtgca tcgccgattt taaaatcact gttgtcagca
     3901 cataggcata cacggcagta atgatgacac caatcacttg aatccctaag aagtaccagc
     3961 tgcttggatt cgttagtaaa tggctgttag atgcaaagat ccctatcaga atcgtacctg
     4021 tgaatccgcc catgccatga acaccccaca catcaagtgc atcatcccat tgtttctttt
     4081 tacgaaaatc aacagcagca tgacagacga tacccgcaat gatcccaatc agcatggcac
     4141 tttttgcttc tacataaccg gcacaaggcg taatggctgc caatccagca acggatcctg
     4201 ttagtacgtc gacaaaatca aagccatttc cttttacttt tgcaatgatc agccaagtaa
     4261 tcatcgcaaa tgcaagagcg atgaatgttg aaccaaatgc attgactgct tgttcatctg
     4321 ctcgaagtgc accaccggaa ttaaaaccga accagccaaa ccaaagcagt cctgtaccga
     4381 tagcagctgc cataagactg ctatgctgac ttctttctcc taaaggaatc tttctttgac
     4441 caagtgtgag gatacatgct aaagagccga atccagctgt cgtgtggatg actgctccac
     4501 cagcgaaatc tctaaatccc atctgatcca aaaatccgcc accccatatc cagtggcaaa
     4561 cagggaaata aatcagcaga ttccaaaaaa taacaagtat aatatagcct tttaaattca
     4621 atctccctgc aaaagctcct gtcatcaaag gaacggtaat cacgataaac atcagttggt
     4681 aaagaaagaa cattaaaaat ggaatcgttg caccatgaaa catgttgggg aagcttgtaa
     4741 catgtctcat caaaaagaaa tctgccgggt ttccaataac accgccgata tcccgtccaa
     4801 aggccaatcc gaatccacca aatacccaca taatcgttgt tatcccaacg gagagaaaag
     4861 attgagacat gatcgttagt atattattct tccgtgctaa tccgccgtaa aaaaaagcta
     4921 gaccaggagt catcaggcaa accattgctg tacataaaat catgaatgct gtatctcctg
     4981 tattgatagg taatgtattc atttttttcg cctcctttct acgattacga gtataaaaga
     5041 aggtgtagtt gtttttttct tctgtttttt tgaattaata cttgcattta taaaagacag
     5101 acaattaata aaagcttgat gtgttgtgct ctttttcgtt tttcacacaa ataa
//
LOCUS       DAZKPE010000123         5096 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000123 DAZKPE010000000
VERSION     DAZKPE010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.125"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(328..1818)
                     /locus_tag="ACG930_002800"
     CDS             complement(328..1818)
                     /locus_tag="ACG930_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFQ0519911.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(1861..2160)
                     /locus_tag="ACG930_002801"
     CDS             complement(1861..2160)
                     /locus_tag="ACG930_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519912.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            complement(2526..2810)
                     /locus_tag="ACG930_002802"
     CDS             complement(2526..2810)
                     /locus_tag="ACG930_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0519913.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            complement(3329..3814)
                     /gene="vanZ-A"
                     /locus_tag="ACG930_002803"
     CDS             complement(3329..3814)
                     /gene="vanZ-A"
                     /locus_tag="ACG930_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFQ0519914.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3967..4878)
                     /locus_tag="ACG930_002804"
     CDS             complement(3967..4878)
                     /locus_tag="ACG930_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFQ0519915.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1532 a          955 c          737 g         1872 t
ORIGIN      
        1 caacttaaat gacctattca ccaagtcaat tatactgcta aaatcatatt aggacaaata
       61 ggtatactct aatgacctat aaaagataga aaattaaaaa atcaagtgtt cgcttcgctc
      121 tcactgcccc tcgacgtttt agtagccttt ccctcacttc gttcagtcca agccaactaa
      181 aagttttcgg gctactctct ccttctcccc ctaataatta attaaaatct tactctgtat
      241 atttctgcta atcattcgct aaacagcaaa gaaaaaacaa acacgtatca tagatataaa
      301 tgtaatggca tagtgcgggt tttattttca gcctgtatca tagctaaaca aatcgagttg
      361 tgtgtccgtt ttagggcgtt ctgctagctt gtttaaagtc tcttgaatga atgtatgctc
      421 taagtcaaaa gaatttgtca gcgcctttat atagctttct ttttcttctt tttttacttt
      481 aatgatcgat agcaacaatg atttaacact agcaagttga atgccaccat ttcttcctgg
      541 tttaatctta aagaaaattt cctgattcgc cttcagtacc ttcagcaatt tatctaatgt
      601 ccgttcagga atgcctagca cttctctaat ctcttttttg gtcgtcacta aataaggctt
      661 gtatacatcg cttttttcgc taatataagc cattaaatct tctttccatt ctgacaaatg
      721 aacacgttga cgttcgcttc tttttttctt gaatttaaac cacccttgac ggacaaataa
      781 atctttactg gttaaatcac ttgataccca agctttgcaa agaatggtaa tgtattccct
      841 attagcccct tgatagtttt ctgaataggc acttctaaca attttgatta cttctttttc
      901 ttctaagggt tgatctaatc gattattaaa ctcaaacata ttatattcgc acgtttcgat
      961 tgaatagcct gaactaaagt aggctaaaga gagggtaaac atgacgttat tacgccctat
     1021 taaacccttt tctcctgaaa atttcgtttc gtgcaataag agattaaacc agggttcatc
     1081 tacttgtttt ttgccttctg taccgcttaa aaccgttaga cttgaacgag taaagccctt
     1141 attatctgtt tgtttgaaag accaatcttg ccattctttg aaagaataac ggtaattagg
     1201 atcaaaaaat tctacattgt ccgttcttgg tatgcgagca ataccaaaat gattacacgt
     1261 tagatcaact ggcaaagact ttccaaaata ttctcggata ttttgcgaaa ttattttggc
     1321 tgctttgaca gatttaaatt ctgattttga agtcacatag actggcgttt ctaaaacaaa
     1381 atatgcttga taacctttat cagatttgat aatcatagta ggcataaaac ctaaatcaat
     1441 agcggttgtt aaaatatcgc ttgctgaaat agtttctttt gccgtgtgaa tatcaaaatc
     1501 aataaagaag gtattgattt gtcttaaatt gttttcagaa tgtcctttcg tgtatgaacg
     1561 gttttcgtct gcatacgttc cataacgata aacgttgggt gtccaatgtg taaatgtatc
     1621 ttgattttct tgaatcgctt cctcggaagt cagaacaaca ccacgaccgc caatcatgct
     1681 tgattttgag cgatacgcaa aaatagcccc tttgctttta cctggcttgg tagtgattga
     1741 gcgaatttta ctatttttaa atttgtactt taacaagccg tcatgaagca cagtttctac
     1801 aacaaaaggg atattcattc agctgttctc ctttcctata aatcctataa aataggttgt
     1861 ttaattaact tggtttgctt tttcattcaa ctgtttcaat attgcatgtt ttgaaaaaga
     1921 tttttttcct ttataagtca atttttttcc actaatcgaa taaattattt tgttattttc
     1981 tattaactta tatatataat cttccccctc cgaagaaaaa tacttatctg attttgtttc
     2041 taagtagata tttctctttt ctaactcttt cttaaacgtt tctagtgtat agatatttgc
     2101 taattttctt atctccaata aactattttt tatataagtt ttacattcat catgattcat
     2161 acaaactcca ccttctataa atgaatacaa aaaaagcaat caaacgattt ccgattgatt
     2221 gcttaacaat tcttaaattc agtagcttag atacttgaaa actctctgat ttccctatat
     2281 aatgatagta cggttatata ccgtcttcaa acaaagttaa ttaaataact tcttacgagg
     2341 gaagagttca tctgactaac tgataagcgt tggtttggca atcttatcgg gctatgcatt
     2401 tataaaatgt cgtcaaacat tttataaatg tgtcatggct cttttttcgt ttctattcag
     2461 ttcgttgttt cgttatatct agtataccgc ttttaaaaaa aataagcaac gatttcgtgc
     2521 attattcaca cgaagtcatt gcttttttct tcttccattt ctaaatccaa tgttacttgt
     2581 tctgattctg tttctggttc tggttctgtt ggctcatttg ggattaaatc cactactagc
     2641 gttgagttag ttaactttgc aatttgttct agtgttttta tggttggatc tgattttcct
     2701 gattctattc gtgaataatt tgatctactc atttctaatt cttgggagaa tttttctttt
     2761 gatttggtac ctctcatctt ttttaagctt tctctaaatg ctagttccaa gtttctcccc
     2821 cctctttttg tgtaataaaa ttcacgcttt atttaaatta tagcttttaa tatcttaata
     2881 aacaagtgat taatcacttg tgatttgtga ttattccaaa agtaggtaat ttcaccaacc
     2941 tttttcaaaa gtttttatcg acgattattg gactggatcg tgtttcctaa agcgattcta
     3001 agcgcatgtt taattttaaa gtgggtaatt ctctttaaaa cgtcctacaa agattcaaaa
     3061 aaagcatggc tgctagtggg ggtaccgtca ggaaaatgcg gatttacaac gttaaggaaa
     3121 tttattaaag agaccaattc ctcagcacta aaattgataa ttgggctttc tttgttacta
     3181 tagtgttagg taagcttttt actttatcac cggttttccc ctcacttcac acctacgggc
     3241 gagtttcccc acatcccgtt ttccatctaa tccaattcat tcaatatctt tatgtgtatg
     3301 aaagatcaga ttgcttgatt tagacatctt acacgtaatt tattcttaaa tgggtacggt
     3361 aaacgagcaa taatacgagc aaaagtatac ctacaaaaat aataactctg tctaattttt
     3421 tttgattcat atgcttattg cttaaaccat ataatttcag tccaagaaag cctccaacag
     3481 tatttgtaat tacatctgtt atgtctgtcg ctccaatagc gaagataaat tgaattattt
     3541 caaaagtaag acttaaaacc agtacaaaag caaacttagg taaaaatccg atttctttaa
     3601 aattgacatt caaaagcaag ccaaatggaa taaagattat aacattatct atcatctctc
     3661 tgaaattccc agtagcagta aatggagtca agttaagact tctttgatga taattaaata
     3721 ctgataaaat attgtattgt aatttgaata acactaacca gattagtgtc actaaatata
     3781 aagctagcaa tcctctagat aatatttttc ccaatataat ttcctctaat tcttttgttt
     3841 aagttgtatc attagtatag caatgtccta gttaacgtgg gttttaaatt aaaaagctaa
     3901 cgttacccca aaagtgctag tacaataatg ctgttcatta atttcgttgg tttcattccg
     3961 ccatccttac ctccttgaat tagtatgtgt tgatccggga aacactgtca caattacacc
     4021 gtctatattg tttcctgata tctcataacg aagattagtc ggcacatgaa tggtggtatt
     4081 tttagtaaca ggataataaa agatctcata tttttcccca tttacactaa cagaaatggt
     4141 tttttcttct tttaggtaat ccatatattc ctcgagaacg aaattctttt ctttcataat
     4201 cgcactatgt ggtaaaccaa catagcgaat atgccatggt tcatattgaa ttcctgttaa
     4261 ctctgttttg tcctctggat aacgtaaaat gaacccgtat ttccaagcat tttcttctat
     4321 ccactttcct tcaggggctc gttccatttt cgtcaagctt gatcctacat ctagtgataa
     4381 acctgaatta tgctcactat aacctgctgg taaggcatac tcagccccca tttcttggta
     4441 aagcacactt tgctcatcaa agtctcgata gccactatta ataataaaat gactaacgcc
     4501 accctttaca gcatcattga ccatctctga aaatttttgt gctatttctt ttgacatata
     4561 aatattacta tcaagcaacc cgtatccatt tattaattcg tcatgtttag ataaattcac
     4621 gatatctgac ttcacacttt cttggcgaac aggatattta ctattgatta atagcagatt
     4681 tccttgataa acctgttctt ctgtaattgt tttctcttgg gtattttcag aagtcccact
     4741 attttctaaa tgttctttgg gattttgatc ataattttga aattcgactt tttcctgaga
     4801 aaacagtgct tcattaacgt agtcataacc taagtatatt aagaataaca ataacaataa
     4861 aaaaaacaac ttcttcattt tcagtctcct ccttaactat atagttggaa gtatgaaata
     4921 tttctagaat cttcccctta aacggcacaa tctcgtttga gattgtgccg ttttgccccg
     4981 taaattacag tcaattattt cgccctactg gatttactat tatcaccaat gtagatgaat
     5041 tttcataagt gatacccatg ctgaatttaa cgaggctgaa ctgcctgttg acaatg
//
LOCUS       DAZKPE010000124         5066 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000124 DAZKPE010000000
VERSION     DAZKPE010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.126"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..254)
                     /locus_tag="ACG930_002805"
     CDS             complement(<1..254)
                     /locus_tag="ACG930_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008177227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0519916.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
     gene            complement(244..1443)
                     /locus_tag="ACG930_002806"
     CDS             complement(244..1443)
                     /locus_tag="ACG930_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFQ0519917.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRRSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1573..2949)
                     /locus_tag="ACG930_002807"
     CDS             complement(1573..2949)
                     /locus_tag="ACG930_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519918.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2949..3605)
                     /locus_tag="ACG930_002808"
     CDS             complement(2949..3605)
                     /locus_tag="ACG930_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFQ0519919.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3615..4892)
                     /locus_tag="ACG930_002809"
     CDS             complement(3615..4892)
                     /locus_tag="ACG930_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFQ0519920.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4911..>5066)
                     /locus_tag="ACG930_002810"
     CDS             complement(4911..>5066)
                     /locus_tag="ACG930_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFQ0519921.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1594 a          924 c          626 g         1922 t
ORIGIN      
        1 gtatcgactt ccttaatggt ttgtcgcatg gaacggatac cgaataaata ctgaataaac
       61 accaatttga tcagaatcac tggatcgata cttgggcgac ctaaatcgga gtaagtggct
      121 tcgacgattg gataaataaa ttcaaaatca agcgcggcat caatctttcg aacgagatga
      181 tcttgaggaa ctagatcatc aatcgtaagc atcgcaaatt gatttctacc attcgtattg
      241 tttttagaca tcatagctat cactccttgc attcgttttc ataaatctat tataaaagaa
      301 aagactgtag acatcatcca taaaatggac tttgtctaca gtctgcgcat tctcattaga
      361 gaacactccc ttttttgtga cttttctgaa gctagagtga atactttcaa ctgcattagt
      421 agtgtacatg atttttctaa tggcgctgcc ataatcaaag agttgttcaa catgagaaaa
      481 gtttcgtttg catacatcta ctgcaccaga ataatgagac cgccgatttt gaaaactgtc
      541 aaaagcagca tgtgcagcgt ttaaagaaga agcactgtag aattttttca tgtctcgaca
      601 gacttcctta taatccttac ttgggaggta tcgtaacgca tttcgaacaa gatgaacaat
      661 acagcgctgc acaatgacag aaggaaaaat tgcttttgcg ccttctttga gaccggaaac
      721 accgtccatc gaaatgaaaa aaacatcttc tacaccacgt actttcagtt catcaaatac
      781 ttgcatccag cgatttttag attctgtttg attgagccat aggcctaaaa tctccttgtt
      841 tcctttaaga tcatagccaa gaatggtgta cacagcatat tctttagctt catagttttc
      901 gcgtaaagtg acgtacatac aatcaacgaa tagaaatgca taacacttgg ctaatggccg
      961 agcttgccat tcttccaatt caggaaggac ggcatccgtg atatcagaaa tcatttcgtg
     1021 ggaaatatca aagccgtaaa tatcttcaac ggttgcggcg atatcgcatt gactcattcc
     1081 tcgtgcatac atggaaagaa ccttaccttc gatgtcggag acatctcgtt ttctattagg
     1141 aatcaactca ggttcaaaag aagcctcccg gtctctggga acatcaatgt ttactttacc
     1201 aaagctcgtt ttaagcgtct tattgccata accgtttcgt cgattgtcat gtttctttgg
     1261 ctctttagaa tgggcgtcat accctaaatg gttattcaat tctccttgaa gcattttttc
     1321 aaataaggga ccaaacacat cttttaaaac atcttgcata tcctctacag attcgggttg
     1381 ataagtattc aaaatggatt cagctaactt ctcagcatca ggatttcttt tctttctagc
     1441 catcgtgtaa tcacctcttg atcttatttt agaaaaataa aaaccgtgaa gcaaccaccc
     1501 gcctaggatt gatggttact tacacggttt atattacact ctcatttttg gtgctaaaaa
     1561 gcaccgaaaa ttttaattat tgtcaattaa taattctttt ggattccttc ttaatatatt
     1621 gaatgaagaa ataatcaatg atacaagaag tactaaactc ataaatataa ctacataaat
     1681 catgaattta ggtaatacat tgatatctaa acttgataat gtcttgttaa atccttcagc
     1741 ttctgcccca ccacctaatt ggctagatgc agattgttta gctatttgtt tagctatatc
     1801 accagtaacc ttattcaata tattattccc aagcttgtca gctgtatatt gagctaagaa
     1861 ataggaacca acgaatgcgg ggattgatat aaataccatc tcaattagga attgaccaaa
     1921 aatttctaat tttgatatac ctaatgatag taatactgct atttctttct ttctagcatt
     1981 catccataag aataataata atgaaactac aactcctgca aatattaatg agccaaaaaa
     2041 taatttattt gaaattgagt aaatacctga tatagattgt tgtaatgcag ggtaatttga
     2101 tgaactttta atcaaattat attctctcca atttatatct aatttcccaa gatcttttat
     2161 tacactatca agattcttat caccttttac aaagaatgtt gcatcttggt atacagctgt
     2221 atcttcggta ttaccataaa ctttagcagc tgtatgaata tcagtgatta atgtattttc
     2281 gtatagttct tgtgctgcac ttactccacc gctattatgc ccatcgaata gacctttaat
     2341 ttctacttct actgtttcat ctgcaccttt ctcattatca gcatcaaata aattagattt
     2401 tatttttatc ttatctccaa ctttaaggtt atttttttca gctaaatctt tatgcattaa
     2461 gattttattt ttatcttcat tttctaaatg ctttccttct actaatttat atgcttctga
     2521 tacaaatttt gtttcttttg ttgagtcgtt aaccccagtt aacataactg ttcttttaaa
     2581 attctttgct ctttcaggtg attgattcgc aagagtctct tgagtttcaa taatatcata
     2641 atcaactaaa tctgcaacac tgtttattct ttttacatag gagtctatac tatctgtttg
     2701 agatatcttt ttaatatctt caccttttac atttccccca cctctaggtg ttcctggatt
     2761 tacttgtcta tttatctcca tagaaaaact atttgttata ttagcaaatg tttcttttga
     2821 agctctgtcc gtagcatctt taatagataa actaatgaga cttaaagttg acatagataa
     2881 aataactaat atgataatta atgattttaa actttttcta gttacataag caaatgcatt
     2941 ttttatcatt attcaacctc caaattcatt ttatttactt ttttcaactt tttaccactt
     3001 agttctaaaa tgatatccgc agaatctgct acttccttac tatgtgttac aactattaca
     3061 catttatttc tatctttagc taatgtcttt aatatattaa ttatttctcc agcagtaaca
     3121 ctgtctagat taccagtagg ctcatcagct agtattattg gagcatctga taccaatgct
     3181 ctagcaatag ctactctttg ttgctgtcca ccagataatt tcataacatt tctttttatt
     3241 tgttttttat ctaaacctag ttcaaacaag atactttcat ctgctgattt atttactaat
     3301 ctaatatttt caattggtga taaataatct attaaattat agttttgaaa tactaaagat
     3361 atattatttt ttctatgatt actatatcct ttattttgta tatcttcatt cttaaacaat
     3421 atttttcctg tttgaggttt atcaagtcca gcaagtaagg aaagaagtgt agattttcct
     3481 gttcctgact ttcctactat cgcataaaac ttcccaagtt caaatttttg atttactcct
     3541 gacaaaactt tttctttaga atttgcataa ctatatgcta cattctttat ttctaatata
     3601 tccattattt tctcctaact tatttttgat aagatttctt taggcttctt gattaacatt
     3661 aatgaagaag caaatacaac tgataaaaca ataatactta ttaatattaa ataactttgt
     3721 ccaagtgttg ttatatttga cataaaacta ctattattta ttaaacttcc accggaaatc
     3781 attgaatcct ctgagttaat gaatccatct acaattactt ttagtaatac atttcctaaa
     3841 aataaggaag atattatact tggtatcgat atgaatatta actcgaatat aaattgcatt
     3901 ataatttgta tcttagatgt tccaatagat aagaatatac ctatttcata aattctttcc
     3961 cttaaccata gaatcaagat taatgaaaga acaaccatcc cacctaacat aatagaataa
     4021 gtcattactt ttattatata ttttattcca ctcactgact ctaaagactc ttcaaacgca
     4081 ttagaatctt tttcaacaaa atactttgac tcatcaattt taagctcttt caatttgttt
     4141 aaggctaagt ctgtagattc tgcactacca gaatacatta aaattttatt tgcaatttca
     4201 ttattttctg aattatttaa tatctcttgg cttgttgaat aatctacaaa caccatattt
     4261 tcactaaaat cagaagataa tcctgtatat gtttcctgtt ttttaccaga aaagatccct
     4321 ataattttaa atttatgact ttttattttt ccactttttt caatatctag taattcaaga
     4381 tcaacttcat cacctaattt tagattgttt tgtttagcaa attcttcatg aacaataatt
     4441 gaattcttat cattttcttc tatattttta ccttctttaa ttgtaaatac tccactacta
     4501 aataaaatat ttcttttagt attatttgta gcttcgagtg aaacaacatt cttaaattcg
     4561 tcagataaat cttctctatt tattctttgt tctccgctaa ctactttagc atcttttaat
     4621 tttgctaatc catcatattg aattattttt tcttcaattt cttttaattt ttcaatatct
     4681 ttaaattgat taacattaaa atatttacca tctttttttg ttattgatat tgaagaatta
     4741 gaactttcat ataaagcctt ttctatttca ttgcttgatt tcattattgt taaacaagaa
     4801 tacaagcaag aaagaactat agttaatatg ataaaaatta ttaaagttct atttttcttt
     4861 cttgtaatat atgctatagc attttttatc actttcctaa ctactcctct ctattttctt
     4921 actccataac taattgcatc cactggacaa gcatttttac atcgtccaca tctgatacac
     4981 tccagatgat tgcaattctc aactgaatct ttattcattt ggcaaacttt tttacatttt
     5041 ccacaattaa tacacttatc cttatc
//
LOCUS       DAZKPE010000125         4813 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000125 DAZKPE010000000
VERSION     DAZKPE010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.127"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(93..1178)
                     /gene="xerS"
                     /locus_tag="ACG930_002811"
     CDS             complement(93..1178)
                     /gene="xerS"
                     /locus_tag="ACG930_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFQ0519922.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            1527..1722
                     /locus_tag="ACG930_002812"
                     /pseudo
     CDS             1527..1722
                     /locus_tag="ACG930_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            complement(3254..3772)
                     /locus_tag="ACG930_002813"
     CDS             complement(3254..3772)
                     /locus_tag="ACG930_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFQ0519923.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            4139..4387
                     /locus_tag="ACG930_002814"
     CDS             4139..4387
                     /locus_tag="ACG930_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519924.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         1582 a          788 c          731 g         1712 t
ORIGIN      
        1 aatataaaaa tgataatgaa gcttgccttt aaagttgggc ttttatctaa ttttagagac
       61 aggcttcatt attatactat tttttactac atttacaaag cgttcaaagc atcaattgta
      121 gctgcattgt ctatatgagt atataaagtt gttgtatttg tacttgtatg tcccaattgt
      181 tgggcagtta ataccaatga atttgtctgt tgatagagtc tagtagccaa agtatgacgt
      241 aatttatgtg gactgacttg gactctgaat ccttttgaat attttgctac catccgttcg
      301 attgcaatac cggatatacg cttggcttct ccttgataaa ttgctagaaa taaagctttt
      361 tcgttttctg ttactttgta tcgttctttc cgaatagcta gataattagc taaatattcc
      421 attgcaaatg ctgctatatt tactgcgtct ctcttatttc cttttctagt tactaccaca
      481 ttattctttt ctaaagatag gtcctctaaa ttaatattta caacctcgga gagtcttaat
      541 ccagatccta aaatcaatgc attgatcgcc aggtctcttt ctacatctcg ttgataatag
      601 atcaaagctc gtttgctcaa agttttttta tattcattgg caatataatc tagataattt
      661 tgtgtatctt cgtctagaaa taattttttc tcgattgcgt ttgcacgggc agctaacgta
      721 gttttatctg tgatagttgc tacttgatcc ataggattat tttctaagta tggttttcct
      781 aaaggattat tggaactttt cgaaagatat ttaaatagaa cctttaatgc tgtgatattt
      841 ctattgatag tagaagtaga tagacctaag ttattattat ctttgagctt agtttttgtt
      901 gtctcttttt ttacattttc ctttgtgcga cgtttcaaat gagatttgta caagtttaga
      961 tcataggcag ttaactgtct tatcgaggtg attgaagtat cgggaacgat agactcactc
     1021 agaagccatt cataaaagag cttataattt tttagatatt ctaaagtagt tcgaggtgat
     1081 tgatctttat cctcacgatc ttgaacaaaa tcttttatat aatcgggcat atgaagtatg
     1141 attgtatcta ttttttgata tatttctgta tttttcatgt tattcatcct ttcgataagt
     1201 aggggagagg agtatctcta taattggact ataccaatta tagagtgttt tgtcaattgg
     1261 tatactctga aatttattaa tttatttcaa aaaagcagat aaataggtat agatttaata
     1321 atttaaaata aatggtatac atgaatagga aaggaaacag aaggaggcaa tcttaatttt
     1381 ttaaattgtc taaattatat agaaagaaca atctttctat ataattagac ataagagaga
     1441 ctacggttga tttgatatta acaagcgtat atgaatgtat atacaaataa aaaaggggag
     1501 ggagaagtta aagaaaattc agagaagtgg ggcactcagt agtattaaca atttaaaagg
     1561 aatttcttaa agaaaatggg ttgcatcctg gagatacaat ttttttagat aaagaaaaaa
     1621 ttcaagcaac aattcaaaaa aatcttaact gctgagattg atgtagcaat atctcaatca
     1681 tcaacaaagt acgatcctgc ctttcaaaag cttattgata aatgtttatt cattataaaa
     1741 ataaaagaaa aatttatgtc agcttttttc atcaaagtgg taatgataat tcgtctatta
     1801 attgtatttt ttaggaaata tggtataatt gttttaacga aaaggtaatt catgatacac
     1861 caaaaaccac tagctggcgg gctagtggtt ttcttttacg ctctattcag attaacgggt
     1921 aggcttactg tcttttttgg caataatttt gcaatcaagc catttacaga tgtaatgcgc
     1981 ggatacttct gctaagattg caaaaaacat atcgaaaagg taattcataa tacaacctcc
     2041 tccccttgcc ataataggcc ggggtagcag acagcataaa tattatacca taactgaaaa
     2101 tttcatttta gtacatttca atatattgat gaaccagcac aataaaacat gccatgacta
     2161 acagaaaaaa acttattaaa ccagatataa cttgtaaaca tccaactata tagaaaacgt
     2221 aaattttcta tatagttgga ttaagataac gactatttat tttatcatat ttttactata
     2281 ccctatactt ttacttggta tatttatgaa taatcgcaaa tttaccccta tactactagt
     2341 ttgtaagtta gattaataaa aatactaaag ttatttgttc ttttattaaa tacacctaca
     2401 acttataaat tgatggtatt tagataacac gaaagaataa aaataacagc tgatagtaaa
     2461 gtttgttgac gattgctact caatcgaaag tgagttagtg cgtatgaact tgcttctgaa
     2521 aacttatgaa atgaaagacc ttttacatct tgcagaaatc ggtactggga ttaaactaag
     2581 caataaaaac taatgttccc ctcattcttt gaacttctac tatttgattt atttattctg
     2641 ataaatgacg atttcacctt caggatcttc aaatcccgta tagaatttat ttaagatctc
     2701 ttcagtatca gtaataggat aggcgatagg ccacataccc tttgatggtt agaataaact
     2761 gctcaaaatc tgtatcgtat gttggcttta gcatattaac aaaggctatc tccaaattat
     2821 aaaccataag cgttgaatcg ttcttaacaa tttcaattct tcctaaccca aagtcagaag
     2881 atataattac cggacttgcc ttacccttca tgtgggttgt tgagattcca tatttaaagg
     2941 gaattgtcgg tactatcggc ggtctgaaaa acatcccaaa aataaaaaaa tctttcccct
     3001 gctagtctcc taagtccctt tgtagcggat atggcaccat aatctcattt tatcgaagtg
     3061 agtcatggtt tatctgttgg ccaaccaaaa ttgatacaat ctaacgatgc accctctacg
     3121 gcattctagg ggagtgcact tgcattcacc caataaaaac cggcagttag caaagaactt
     3181 atgtagtcgt atgttcttac tgttaacata caagaggtct cctttccaca attgcttagc
     3241 agtaaacggg aatttacaaa gctaatctct tccattttct tatctttgtt ctaaaagtcc
     3301 caaatggagc aactgtattt acatgaataa atttatatac ttcccataca gccgttttgg
     3361 ttgcctcgtc tgcccatttt cttttgtgtg cagtgaatag atcttcatca ctcattgaat
     3421 caatcatcat gttaatatca tcaatattac gattgagaat ttcctctaat tctttcaatg
     3481 gtagatgtgc ataggtattt gtaaaccact tatataactc tcctaactga ttccatttaa
     3541 attgatcaga aggcgtttta acagataatc catttctttc atcattttcc cattttagaa
     3601 ttaaattcgt ccaaccaact tgatatgcta aattttcagc aggtgttcta tccacttcct
     3661 caactctttt atccttcaat tcttcaggaa tagtttcaaa ttctaaaata tatttagtat
     3721 aagtcctatt tatttctttt tttaattctt ctttattttt atatgttctc attatattac
     3781 ctccataaat tcctaattgt ctcctttaat tcatctataa tttcatccac gatattttaa
     3841 tccgttctac aatgcatatc tgatatgcat tgactgtcta actcatatgt gaatgattta
     3901 taaaatatcc caacgtctca tctaaagaaa tgttgatcgt cagcaaggag ctaaaaaata
     3961 cgaatatatt tcttttgtag taaaatcgga ctggtttgca tatcattttc ttcgtaaata
     4021 tcaaaatcat gttaactact atcaattact aataaaaact accactttaa gcgttaagaa
     4081 ctgttaagtt tagttaagtg aggatagttc acaaaatcca ttgttaaact tcacgaaagt
     4141 ggtaaaactc aaaatgcttt atataggatt acagcatcgc tctttcttcg attgcgcgtt
     4201 gggtaaaaaa tattatgaag taaaaattga cgatgacacg ttccttacgg ctcatcagat
     4261 gaaacagcta caaaaacgaa atgatcaact cgaagaaaat ttaattctaa aaaagcgatt
     4321 gccatattca cgcctcgctc gacgaactat taaaggtcaa gatttacctg aagatcatcc
     4381 tttttaggaa attgaagctt tttatgttgc acaatgcatt tataatacta caatgatgtt
     4441 ttcaccagat attcttctag ggtgcggtgt aatgaaacag atacacttgc aaaagaaaat
     4501 tcaccgcgaa tttactaaaa ttatgaataa ttatgttaat cttccgaaat ttttttccaa
     4561 aattaaggga tcaagctggt gttatagatt gtttaaggtt ggcaaaaaaa taacttcttt
     4621 ttaaacaatt atagaaaacc gatactctgt taagttggtt gacacggtgt cgatttttat
     4681 gactttctta ttctgaaact tcactaacgg acagtaccta aaaagtctat agtatggacg
     4741 tttacgagta ctattttatc aaaaatgctg ctcatttcaa cttatatgtt ttagtgaact
     4801 acccccactt agc
//
LOCUS       DAZKPE010000126         4761 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000126 DAZKPE010000000
VERSION     DAZKPE010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.130"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            59..205
                     /locus_tag="ACG930_002815"
                     /pseudo
     CDS             59..205
                     /locus_tag="ACG930_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="ACG930_002816"
     CDS             282..611
                     /locus_tag="ACG930_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0519925.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="ACG930_002817"
     CDS             601..888
                     /locus_tag="ACG930_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFQ0519926.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="ACG930_002818"
     CDS             1174..2031
                     /locus_tag="ACG930_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0519927.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            2032..2580
                     /locus_tag="ACG930_002819"
     CDS             2032..2580
                     /locus_tag="ACG930_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519928.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            3356..4023
                     /locus_tag="ACG930_002820"
                     /pseudo
     CDS             3356..4023
                     /locus_tag="ACG930_002820"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         1730 a          631 c          981 g         1419 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggactggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgcgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataagc aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaacaa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac tgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgatc
     3301 aattattctt aacgatccta attggagtaa acaagctaat ttaagagaga ttagcatgcc
     3361 atccgcttgg gaagaaacca agggttctaa ggatgtgaag gtagcggtca ttgattcagg
     3421 aattgattat caacatgaag atatttctgg aaatgtagat gaaagtttgg gatacgattt
     3481 ttttgacgat gatacagatc ctatggatac tatgggacat ggacacatat tgccgggatt
     3541 attggtgatc aaacaaacaa cgaattaggt gttgctggaa taaattggga tgttacgatg
     3601 gtacctatac gtgtatttgg tagtagtgga ggtaccagtt tggcaatctt tactgaagct
     3661 attaattatg catcccaaaa agggtttcca attatcaatt ttagtatagg tagtgttgtt
     3721 tatagcagta cagaagaagc aattaaaaac tatcctggat tattcgtagc agcagctgga
     3781 aataatggga tagatatgac tgataaacct ttttacccag cttctttgga tatacctaat
     3841 attattactg taggaaattc tagtggttat gaacgaagtt ctgattcaaa ttatagtaaa
     3901 acaggtgttg atttattcgc tagagggttt cgtgttttta gtacatttct aggaagtaaa
     3961 tacacgtata tgtcaggtac ctcgatggca acacctcatg tcactggtag tgctgcatta
     4021 gcgttgtcac tagatcctga tctatctact gatgaattaa aaaaaatcat tttaaatagt
     4081 gttgattcat tttatgaact atctgattta tgtcttacag ggggaagact aaatacgaat
     4141 aatgtcgtac gacaagtaac gggtaaactt actgcatcta atatcacatt aagattaaat
     4201 agtgaatggt cagatgaaat tgctaaagag atgtgtcacg ttcactggat tgaccagtca
     4261 ggaaatgatt tgacggatca agtggttgtt ctaaaaaacg aagtggatac atctaacttt
     4321 ggcgattacg aagtagtatt tgcatcacct gatttaacag atcaaatctc agttacagtg
     4381 accgtacctc gattacgtaa acttacgcta ggaaaagaaa cagcaaccat tgatattggt
     4441 tccgcatggg atagtgtcat agccattgat acttttcaag tgaaagctat agatgatttt
     4501 gggaatgatg ttacaaatca agtacaggtt actattaatg ctgatataga tacaattaat
     4561 tcaattcaag cagtgattaa gtttgaagtt ccagaattag gcttagccca aattggtaga
     4621 ctgaatatta ctgcaaaaaa tagtacaatc aatggattga atgaagttag catcgagcac
     4681 gtaaaaaaga ttatgtcgtt ttcgaagaag aatttggaca tttagagggt gatacgattg
     4741 tcggcatcca ccataaaagt g
//
LOCUS       DAZKPE010000127         4760 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000127 DAZKPE010000000
VERSION     DAZKPE010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.131"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(25..1257)
                     /locus_tag="ACG930_002821"
     CDS             complement(25..1257)
                     /locus_tag="ACG930_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFQ0519929.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1512..2081
                     /locus_tag="ACG930_002822"
     CDS             1512..2081
                     /locus_tag="ACG930_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0519930.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2259..2699)
                     /locus_tag="ACG930_002823"
     CDS             complement(2259..2699)
                     /locus_tag="ACG930_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFQ0519931.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2857..3621
                     /gene="map"
                     /locus_tag="ACG930_002824"
     CDS             2857..3621
                     /gene="map"
                     /locus_tag="ACG930_002824"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFQ0519932.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3653..4576
                     /locus_tag="ACG930_002825"
     CDS             3653..4576
                     /locus_tag="ACG930_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFQ0519933.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
BASE COUNT         1451 a          883 c          930 g         1496 t
ORIGIN      
        1 ttttgcatgt gtgcgaaagt atactcaagc ccaatcgcca tttcggaaaa tcggtactgt
       61 agagccatct tcacggattc cgtcgatatc catcttgtca gatcctacca tgaaatctac
      121 gtgggtttga cttctattca atccagcttc tgctaattct tcatcggaca tttctgtacc
      181 gcctttcaca ctgaaggcat aagcagaacc tagtgctaag tgattcgatg cgttttcatc
      241 aaataatgta ttgaaaaaga tgatgccaga ttgagaaata ggtgaagggt caggtacaag
      301 tgcgacttct cctaaacgac gcgcaccttc atctgtatca agcagttttg ctaagacatc
      361 ttctccttgt tcggcagaaa aatcaacaac ttttccatct ttaaaagtaa atttcatacc
      421 cgagatgatg gtgccagcat aactcagtgg ctttgtactt gaaatgtaac catctactcg
      481 atgactgtca ggtgctgtga acacttcttc cgtcggcata tttgccatga atttttctcc
      541 acgagcatta tagcttccag cgccttccca aagatggttt ttaggcaatc cgataatgat
      601 atctgtaccg ggagcagtat agtgaagggc agaaaattgt tctcgattca attcttctgc
      661 tttttttgct aatttttcat catgcttctt ccatgctaag acagggtctt cttcatagac
      721 acgagtcgtt ttgaaaatct gatcccataa tgcctcaact tgtttttctt ctggcagttc
      781 tgggaagact tttgctgccc attgtttacc agccgcagcc acgacagtcc aactgacttt
      841 atttgcttga gttgccttgc gtaaattcat tagtgctttg ccattcgctg attgataaga
      901 cgctactcga tggctatcta caccagcaaa tgcatcggga tcggcagaaa caacgctgat
      961 cctgcttgct cctttttcaa gccattcatc cgcttgatcg attttagatt gtggtacatt
     1021 ctcaatacga tccgttgcag catgtaaaag aaattctctt tggatctggt cgtcagtcca
     1081 ttgaacgata acctcagcgg ctcctagttt ataagcttct tgtgtgatca atcgagcaag
     1141 gggtgcctgt tccacgctga tctgtaaaac aactgtgtgt cctttttctg tggctacgcc
     1201 agtttctgca attaagcgtg catatttttt tagaagttca ttaaaatcag ataacataat
     1261 aaaaattcct cctcaccatt ttttctggta actattagca tgataccatt taattatgat
     1321 tcaaacaatg aggctttaaa taaaaaaagg aggttatttt tttaaggtta agtttcatga
     1381 tatatgttac tacttgctat ttcagcttgt gaagaaaatc aaaaactaat tttgcatatc
     1441 aaaaaaaaca tgttacaatg aaattaatca atggtggaag cgttataaaa aaattaagga
     1501 gattaaaaaa tatggcaaga aaaaagacga ttactagaga acagattttg gcagctgctt
     1561 atgaagtagc tgccaccgat ggatttacac gatttactgc gagaaacatc gcgaacaaaa
     1621 tgaattgttc cacgcaaccg atttatcttg agtttaaaaa tatggatgac ttgagacaag
     1681 ctctttttga gcagatctat gatcatttac aatatgaagt gttcactgtt gagcatacag
     1741 ggaatacgat tatcgatctt gcttttaatt atatccattt tgcaagaaga gagaagaagt
     1801 tgtatcgttc actgtactta gaagaatatg gtggaggaaa agagatgcag aatttctctt
     1861 atacttactt tgtgaataca gtgaaacgcg atccagctta tgtgaatctt tcagaagagc
     1921 agatcgaatc tttgtataat gggacatgga tcatagctac tgggatcgca gctttgatgt
     1981 cttcaagcat catccatcca actgatgaac agattgaaaa gatgatccaa gacagtatag
     2041 atgctatctt gaaattcaaa gaaccaatcg aaatcgattg aatatactca aaagttccac
     2101 aaatcagtag gtaacaagag atgtgtcaaa ataaggaaaa gttcgttttt cttacagcgt
     2161 atgcattttt aactcccgaa gaactcttcc atgaatgcaa tgaataaaag agccatacag
     2221 attgaataaa tctggatggc tcttttattg caagtatatt aaatttttgc gactagttct
     2281 ttagcgaaag cttctaaatt ttcgatatct tcttcttcag cattcagatc cactttaaca
     2341 ttttcggctc cttttgatgc gcctgttttt gcaaaagcag catcgaaatc atccaccgat
     2401 ttgcagaatt catcgtaaaa agtatcacca gatccgcaga caccgtaaat ttttcccaat
     2461 agatccaatt cttgcaagtc ttcataaaag tctacgatct catcaggcag atcgccatca
     2521 tcgtatgtat aagtagctac tacgcaaata tctgcctcct cgaattcatc tgcatctact
     2581 tgggtacatt cgttgatttc gacttcgata tccagatttt caaatgcttc tgcaacaata
     2641 tcggcgattt cttcagtgtt tcctgtcatg ctagcatata cgatttttgc taaagccatg
     2701 atgtgcctcc tcgtttataa ttatttaaca attatgaatt ataccaaaac atcattgaaa
     2761 agaaaataaa acctagagac acctggggaa tgtcatttgg ctaaatgtat gccgctatgt
     2821 taaaatgaga gggatttgta aaaaggagac gaaaatatga ttactttaaa atcagcacgt
     2881 gaaattgaaa tgatggcaga atctggagct ttattagcag atgtacataa aaatctgcgt
     2941 gattttataa aaccaggaat cacaagttgg gatattgagg tatttgtcag aaactatatc
     3001 gagagtcatg gcggaattgc tgcgcaaatt ggctttgaag ggtatgaata tgcgacttgt
     3061 atcagtataa atgatgaaat ttgtcatgga ttccctcgta aaaagccttt gaaaaacggt
     3121 gatttggtaa aagtcgatat gtgtatcgat ttgaaaggcg gcatttctga ttcttgttgg
     3181 gcctatgtag ttggagaatc tacacctgag atcgaccgat tgatggaagt aacgaagaaa
     3241 gctttgtaca tcggtattga gcaagcacaa gtagggaatc ggattggtga catcggtcat
     3301 gctatccaaa cttatgtaga aggcgaaaat ctagcgatcg ttcgtgattt tattggtcat
     3361 ggcgttggtc ctacgattca tgaagaacca gcagttcctc attacggaga agctggaaaa
     3421 gggttgcggt tgaaagaagg catggttatc acgatcgaac ctatggttaa taccggaact
     3481 tggaaaatga aaatggatcc taacggctgg actgcgtata caagagacgg cggactttct
     3541 tgccaatatg aacatacatt ggctattact aaagatggtc caagaatttt gacatcacaa
     3601 ggagaagaag gcacttattg atctatccag tcaataggta cgggagaggt acatgaaagt
     3661 ttggaacaaa ataaaacaaa atgaaaatct gatgcgcttt attgagacga ctcaaaagcg
     3721 catcactgat tcagaaatga gtacgacctc tgtcgtcgtt gcttattatt tactcttgtc
     3781 tttatttcca ttgattattg cttttggtaa tattttaccg tttctccaca tcgatcaaga
     3841 gactgtactg acctatttac gagaagtgat tcctgagacc gtttaccagt ttatcggtcc
     3901 tgcaatcaaa gaccttttga cacaaagttc aggaggcttg ttatccgttt ctgcattagc
     3961 ggctttatgg tctgcaagtc aaagtatcaa tgctttgcaa attgcgatga ataaagcgta
     4021 tggcgtagaa aatagaaaaa attttttgat cgtccgtttc ttctcactaa ttgtcattgt
     4081 cttgttcatg attgctatta gtggggtaac tatcgttctt gggttgggac agctgatttt
     4141 ggatgctatt cagccaatcg tacaaatacc cgtgaacttt atcgatcagt tccaaacttt
     4201 gaagtggcca atcacattgg tagctttatt tgtcatcatg ttcttgattt atttaattgt
     4261 ccctaatgct cagttgaagt tgaagacgat cattccgggc acgatcttcg ctactgtcgg
     4321 ctggatgctg ttatcacaag tgtttagtat ctatgctagg tattttgcaa cgaggatcag
     4381 cggttatcag atcataggaa gttttattgt actcatgctt tggcttaatt ttgctgctac
     4441 gatcatcatt ttgggcggaa tcatcaatgc agttgttcaa gaatacgtga cgggtcatca
     4501 aatcaaaaaa cgtcgagatc caagccgaaa atggttcaat aaattgaaaa ctaaattttc
     4561 tcataaaaaa aagtagaaac aagagttctt attgtaaatt tatatcagta atttatttga
     4621 aattttatat ctaattttca attatccgca taaacactat acattcaagc attttgaagt
     4681 atagaaaaac actcatctta ccacgaattt accacgattg aatgagcctt gatatgaccg
     4741 taaaactact aagggagata
//
LOCUS       DAZKPE010000128         4633 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000128 DAZKPE010000000
VERSION     DAZKPE010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.132"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            105..1532
                     /locus_tag="ACG930_002826"
     CDS             105..1532
                     /locus_tag="ACG930_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFQ0519934.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDHLYMKPVRELEQLRVG
                     SGVETKVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            1545..2417
                     /locus_tag="ACG930_002827"
     CDS             1545..2417
                     /locus_tag="ACG930_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0519935.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNELLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            2512..3507
                     /locus_tag="ACG930_002828"
     CDS             2512..3507
                     /locus_tag="ACG930_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFQ0519936.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKDN"
     gene            complement(4112..4219)
                     /locus_tag="ACG930_002829"
                     /pseudo
     CDS             complement(4112..4219)
                     /locus_tag="ACG930_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISCbo2 family helper ATPase
                     IstB"
     gene            4335..>4633
                     /locus_tag="ACG930_002830"
     CDS             4335..>4633
                     /locus_tag="ACG930_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFQ0519937.1"
                     /translation="MIIKNLGNVKSIDIHVKDLLIFTGKNNTGKTYTSYILYGILSEL
                     FGARFFNYFSHTEIEPHLQNSLNILLVSKDSIRKKFNNDAKKFLEENLKKIAVRN"
BASE COUNT         1690 a          618 c          880 g         1445 t
ORIGIN      
        1 cttaaacaag atgatagaga tgttcaaggg gatccattta ttcgaggata atggaaacca
       61 acagaataaa aaacaatttt atctagaaag tgagcgaata tattatgaca aaaagagcta
      121 tagaattaac aaatacacgt tatcgtttgg gatatcatgt gtctgcacca tcaggatgga
      181 ttaatgatcc aaatggattt tgctattttg atgggtatta tcatgtgttt tatcaacatc
      241 atccatatag tgctgaatgg ggaccaatgc actgggcaca tgctagaagt aaggatttag
      301 ttcattggga atctttacca cttgctttga ctcctggaga tcaagaagat gaaggtggtt
      361 gtttttcagg aagcgctatt gaaaaaaatg gtgtgttgta tctgttctat acaggacatc
      421 actattatgg agacaatgat ccagatcatt tttggcaaaa tcaaaacatg gcgtatagta
      481 cggatggcat tcactttact aaatatgaaa aaaatcctgt aatagcaaaa gcaccagaag
      541 ataacacaca tcatttcaga gatccaaaag tatggaaaca cgatgaaaaa tattacatgg
      601 ttttgggtag tcaagaaaaa gatggattag gtcgtgctat tgtttatcag tcgttagatt
      661 tattaaattg ggattacatt ggaccaattt ctaaagcgaa ggaagtactt acagaaggat
      721 ttatgtggga atgcccagac ttttttgaat taaatggaaa atctattctt ttattatccc
      781 ctcagggaat tgaagcaaat ggaaaagatt atttaaatct atatgaaaca ggctacttta
      841 tcggtgatta tgattatgag acagcaaaat tcattagagg aaatttttat gaattagata
      901 agggacacga tttctatgca acacaaacaa ctttatctcc agatggtaga cgtattgtta
      961 tggcttggat ggatatgtgg gaaagcccta tgcctgaaaa agtagacgga tgggcaggag
     1021 cattaacgct tcctcgagaa ttagagttaa ttggagatca tttgtatatg aaacctgtga
     1081 gagaattaga acaacttcga gttggcagcg gcgttgaaac aaaagttaat ttggcaggag
     1141 aaataataat cgctcaagat gcttcattca aagaagctct aattgatgta ctattgacta
     1201 aatcaaaaaa tcaagaaatc aaattttcat taaaaacaaa agatgaagag ttaattaata
     1261 ttttttattc taaggataaa aatgaatgta ccttaactcg taacggcaaa aatgatccaa
     1321 ggtatggaac cattcagatg tgtgatagat tatcacttcg agtgtttatc gataaaagtt
     1381 cggcagagat ttttattaat gatggcgagc ttgtttttac agagcgttat tatacagaaa
     1441 atcaaccaag tatgcatttg agtgttagtg aagaagcttt tgtctcgagt acaatttatc
     1501 atctaaaaaa agatgcaatt tcttacgagt aaggaggttt tatgatgtta attggtagca
     1561 tagaagcagg tgggactaaa tttgtatgtg ccgtgggaga cgaggattac cgagtacaag
     1621 accaaataat ttgtccaacg accaccccca gggaaacatt gaaaaaaact gttgactatt
     1681 ttaaacagtt tgatataaat gcattaggta ttgcatcatt tggtccaata gaaattcgaa
     1741 aaaattcacc aaaatcagga tatattacgt ctacaccaaa ggtgggatgg cgaaatgtta
     1801 atgtgttagg ttatttacaa gatgagctga atgttccaat gtcttggaca acggatgtga
     1861 acggatcagc ttatggagag tacatcatgt ccactttatc gaatgaaaaa ataaattcat
     1921 tagtttatta caccgttggt actggcgttg gtggtggagc tgttgttgac ggaaaactat
     1981 taggatcgtt tggtcattca gaaatgggcc atacgtttgt aaaacgccat cctgatgata
     2041 ttgattttaa aggaatttgt ccttatcatg gtgattgttt agaaggctta gttgcgggac
     2101 caacgtttga agcacgtttt ggaaaaaagg gtgaagacgt ttctttaacg gatcctattt
     2161 gggatgtaat ggcctattat ctagcacaag ctgtgattca aacaacattg attatacgac
     2221 cggataaaat agtatttggt ggaagcgtag taaatgaaaa attgttagaa aaaattcgtg
     2281 ttaatgttaa tgaattattg gatgattacg tggaaatacc accgttaagt aaatatatta
     2341 cgcgtccttt aattaaaaat aatggatcgg caacactagg aaactttgct ttgggcttga
     2401 atcaattaca agaataaaac atagaaaaaa tatcgattat caggtatagt agttctatag
     2461 agttcttttt ttcgatagtt aattattgca ttatttagga gagacaagag aatgcgccca
     2521 aaattagaag atgttgccaa aagagcaaat gtatcaaaaa caactgtttc acgtgtatta
     2581 aacaatcgtg gctatttaag tcaaaaaacg attgataatg tttataaggc tatagaagaa
     2641 ctcaattatc aaccgaacgt tgtagcgcgt caattatttc aaaagaaaac taacattgtc
     2701 gggttactat ttcctacagt agccaatcct ttttttagtg aactcgttga ggcattggaa
     2761 aaaaagttat atgaaattgg ttataaggta ttaataggca attcgatgaa taataaagaa
     2821 aaggaaacaa attatttaaa tcagttattg tctgatcaag tagatggttt aattgttggt
     2881 acacataacc aagggattca ggaatataaa tatcagaatt taccgattgt tgcaattgat
     2941 cgagtgatga atgaagatat tccagttgtt gaatccgata actacaatgg tggaaaactt
     3001 gcaaccaagt tattaattgc acaaggtgca aaaaatatta ttcatacaaa cggtccaatt
     3061 gacttacaga ctccggctaa tcgtcggaga ctagcctatg aagatactat gaaagcatat
     3121 cagttaattc cacgaactgt gacattagat ttcaatattt cttatgtaaa gaaaaaacag
     3181 atttttttcc aaatgtttga ggattatcct aaaatagatg gtatttttgc ttcaaatgac
     3241 atcgatgcgg ccctaatatt acaagtagca aaagaaaagg ggttaaatgt accagctgat
     3301 ttattagtag tcggatatga tggtacttta atgactcgga gtatattacc agatctgaca
     3361 acagtaatac aaccaattaa tgatatagca gacacagctg ttgctatttt gatgaaacga
     3421 ataaataaag aagaaacaaa aaaggaatat attttacctg tcacattatg gatggggaag
     3481 acatcagtaa agaaaaagga caattaaatt tataaagact atcaatgata atttcattat
     3541 taattcgtga tataaaaagt tgttaaatct cttataatag actatgatac aaaatcatgc
     3601 ttttaatctg tgtagatgtt gccaaatatt tgaaagacat agaacttgtc agaaaaacct
     3661 taacaattcc tcaatgggcg gataagctag gcaaaagggc tggcataaac ttttcagtcc
     3721 ttctaacaga atcaattgca gataaagcag ataacattct tctttctgga agaaataatt
     3781 agaactcaaa agggtcagaa acttaaaagt ttttgatcct ttattttcaa gtctgatttg
     3841 acagattttc ggcagctcat ttatttatgg tcagaaatag ttgctgaaat tttaatctat
     3901 tagcaaatag tccagaacgt atgaagagga ttcggatatc atttgtcatt aacaccataa
     3961 atatttataa aattcgtgtt cacctacaat taaatttaat atataatatt cgttgtaagg
     4021 gcttataatt ttttgttaat gaacaagata tgtaattgat agtgtcaata gctattcaaa
     4081 aatgtaggct tttggcccat aaataacaag gttacttata tgataacttt ttttctttat
     4141 aatctttaat ccgatagagc tttccagtag tttgaataat cttagcgtgg tgcactaatc
     4201 gattgattag tgcatttgtg ttcagtccat tgagacataa tagtggatag ttttactgag
     4261 aaaattgata aaaaatagag atataattca aatacgtata taatgaaact aaagataaat
     4321 acggaggaaa atatatgatt ataaaaaact taggaaatgt taaatcaata gatatacacg
     4381 ttaaagattt gctgattttt actgggaaaa ataatacggg aaaaacatat accagctata
     4441 ttttatatgg aattttatca gaactctttg gagcaagatt tttcaattat ttttctcata
     4501 cagaaattga accacattta caaaatagtt taaatatttt attagttagc aaagactcta
     4561 taaggaaaaa atttaataat gatgcaaaaa aatttttaga agaaaattta aaaaaaattg
     4621 cagttcgtaa ctt
//
LOCUS       DAZKPE010000129         4631 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000129 DAZKPE010000000
VERSION     DAZKPE010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.133"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(977..1150)
                     /locus_tag="ACG930_002831"
     CDS             complement(977..1150)
                     /locus_tag="ACG930_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519938.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1153..1551)
                     /locus_tag="ACG930_002832"
     CDS             complement(1153..1551)
                     /locus_tag="ACG930_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519939.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1767..2822
                     /locus_tag="ACG930_002833"
     CDS             1767..2822
                     /locus_tag="ACG930_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519940.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2842..3195
                     /locus_tag="ACG930_002834"
     CDS             2842..3195
                     /locus_tag="ACG930_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519941.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3377..3664)
                     /locus_tag="ACG930_002835"
     CDS             complement(3377..3664)
                     /locus_tag="ACG930_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519942.1"
                     /translation="MKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAKLKS
                     DSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3677..4495)
                     /locus_tag="ACG930_002836"
     CDS             complement(3677..4495)
                     /locus_tag="ACG930_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0519943.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
BASE COUNT         1589 a          790 c          637 g         1615 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttt cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaaatca aaatttaaat gttttaatat tacaaataaa atcatgttat
      541 tgtaaaatgg tataaaaaag ctaaatattt tatttttgtt attttattag caggaaaatt
      601 taaatagttt tacaagaatc cgtagaaata tattggtttt gccttcagat taatactgga
      661 tcatattaat ctgaatataa tatatgaact aataaatagc ttaacctcgc tattttgttt
      721 tttctgatca ctatctatac agcattagta aatagaattt taaaaataaa aaaattaaga
      781 caaaaaagta tcaacataaa catatacata tacacgttta tgttgattca cttaatttgt
      841 cctttaaaaa gcacttattt taatataatg ttattttata atcttattac aagctgattg
      901 ttaggcgttg tcctttcatt acatttatta acggttattt tattgtttaa tttattaatt
      961 atttttgatc taaaacttag cttaacaaat aaataattaa ccaaccgcca gataaaaatg
     1021 cgatcattgc taatacataa gcaaagataa aaatatgttc gatcagctta aaccctgatg
     1081 cgattaagca gaccaagtaa aatagaaatt ctcttacaga taatggtaat tttctaacta
     1141 gcatactcat aattaacacc ccaaagtaat attgtatttt gaacatttta catccaatac
     1201 agcatcaatc aaccattgcc aatcaaaaat acaaggcttc attgaagtat gtttttcaga
     1261 tgaaaagata taatataatt tcttcggaat aatattttca gttgttggga tcaagctaaa
     1321 tctaataccg tctaactcat agctaccagc tttctctcca ttaaaaattt ccttagcact
     1381 ttcttctaaa gaatcaaaat atttttcgac agcaatcttt gaagctttta ctattgaagc
     1441 atttcccttt tcgataaaat ctgcttttgt tttaccgaca ataagtaatt cttgatcagt
     1501 aaaatcttct aaaataatgg tagtgtaatt cttatttctt ctcaatcgca tcaggatcac
     1561 tccttaatat aatttatgtt tttataatat cataataaga taaatttgca agcatttatt
     1621 tacacctttt tatttacact ttattataat taattagact tttatgattg catttttttc
     1681 ttataaacag ttgcaactaa tagtaaatag gtgtaaacta ttttcgtacc gaaataccat
     1741 aaacacaaac agaaagaggt cataccatga aagaaccatt attgttttcc gttgacttag
     1801 ggaataaatc agtaaaagaa atgagtacac acgtttctcc actctcactt ccctctcgta
     1861 ttttgaacaa aaatatcatt aattcaggac gtttttctaa tataggttcc tcattaaaac
     1921 gatcactaaa cgtttctgaa tatagcctag taaacactac tgaaagctat tactttggga
     1981 aggatataca cgagctagga aaagatgact acgtgataga atcactaggt tttgggatca
     2041 gcagatacaa gcaggaaacc taccaaaata tcctatcttt ctctttagct aacctagcac
     2101 gtttagaaga tcaatctgat gacgttttaa ccgctaatct agttttaggt ctgccttcat
     2161 ccgactatac cgaaacaatc gtcaaatacg tgatgcaaca agccacacga caacattcag
     2221 ttgaagttga cggtaaagct tataatataa acgtagatac cgtttgggta ctgccacagc
     2281 cgattggaac actatataac ctcctacttg ctgatgatgg tagtgtacaa gatgaaacat
     2341 tgatcagtca gaagatcggt tttgttgata ttggcggtgg cacgaaactt tttgatgttg
     2401 tccaaaattt tgaaattgac gaaaacaatc gtgaacaaaa ggataccggc atttttactt
     2461 tatataatcg tatcgtaaat atgcttgacc ttccgatcag tcctaatgct ttccaacttg
     2521 aaaagattat ccgagaaggc aaagaaaaag gcgtatatct atttaagcca agcggaaatg
     2581 aaagttttga tatttcagaa gtagttgaaa gagaaataaa aacatacacc aatatggttg
     2641 ttgcagaagt tttagctaca ttcaaaaact tcacaacctt agataaagtt gtctttactg
     2701 gtggtggagc ttctattatc gacaaacaac ttgtaaaaga taaaattccg cataccttgt
     2761 ttgttgaaga cagtgaattt tctaatgtaa aaggctttta caagtttggt ttaactcaat
     2821 aaaacagcga aggagatcaa catgaataag ggaaaatcag agcgttatgt agttataatc
     2881 aatagagaaa aggttagcga gttaccttta gcagagtttc ttgaatccga atatgaaaca
     2941 ctaggcgtta aatactctca gacgatcaaa aaagctttga acctatatcg gcgtgtaaag
     3001 aacaatgaag ttacaattat tgaagcaggc aacgatagaa acgatagcaa agtagcagaa
     3061 gtaaagaata aaccaactga tcataaccct attcaacaag agcatccttc aacggttaca
     3121 tccgatcatt cagcaaagaa agaaaagcca atgctgaaag ggttcaatgc accaagtaac
     3181 aaagacttac tttaaaaata aaaaggcgag gttacaatac ctagcctttt tattatgtac
     3241 aaatataaac ataaacatat acgtatacat gtatataaac atgtatacgt atatatccat
     3301 aaacacgtat attaaattta gttaagctat acctaaccgc ttattccaat aaaaaaagtg
     3361 atcagcttta aactgatcac tcaccaaaaa cttcatcata caagttatct atcatttcac
     3421 caagtaaagc tgaatctgat cgaattccta acttttcgct gattttagat agtttctttc
     3481 tttgcgatgg ttgaagcgtg aattgataat ttttcttctt ttcagaacta tcacttttta
     3541 gtttagctac caaagaactt gttgtttctt taggtgtttg tttaggttct tcaactgctt
     3601 caaccacttc aggaacttct tctacttcag cttcagcgaa ttttttaaat ctattttctt
     3661 tcacttcaat cactccttat tcttgtgccg tatcaattat tttgttgtat agcgtaaacg
     3721 tgctttcaaa gaaatcctta ttcttacgat agatattctt atccttagcg aactcagcaa
     3781 tattcttacc ttctaagcta gttgcattaa gcaattcctt ctcttgtaca tatccaagat
     3841 aattagataa cgttggtacc agttctagga actcacgact tgaattagta ttatgtttga
     3901 tcctgctacc gatcgtagcg tatttagttt ccatcagtgt ttcaccagtc ttaatatcaa
     3961 tcaactgttt tgctagtgca tcaatatctt taccaagctt cagcaaagct tcaaaaccat
     4021 ctttagatgg atcagaaatg cctacgacaa gatcagatac agcccaagca ttttgagcta
     4081 gtagacctgc atcattatga gtatcaatca gaattagatc atacttctct ttaagctgtt
     4141 catagttaac aaccatccat ctaaacagta gggttctgtt gttaggcata tcacgcattt
     4201 gcatctcaac ttgttttaaa tcttcacctg ctactaaaat atccatgttc tcatttacag
     4261 ctaaaggttc agctgatcca tgaagatata aatgattgat tgtattctct cttttcgctt
     4321 tactgaaagc atcaggaaat cgttttgata ggttttgcga cttatcttca tcaatataca
     4381 gcaccttcat acctaaattt tcgacagcat atccacctag attgtagatt gttgttgttt
     4441 tacctgttcc acctttttca atgtttccag taatgattga caacttcttt tccatgatta
     4501 aacctccctt attaaccttt tgtaactcca ttatacacta taaacacgtt tatgtatatg
     4561 tttatataca taaacgtgtt tatatttata tttgctttta tattctacaa cataaacata
     4621 tatatgtata t
//
LOCUS       DAZKPE010000130         4487 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000130 DAZKPE010000000
VERSION     DAZKPE010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.134"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            79..516
                     /locus_tag="ACG930_002837"
     CDS             79..516
                     /locus_tag="ACG930_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519944.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            611..1495
                     /locus_tag="ACG930_002838"
     CDS             611..1495
                     /locus_tag="ACG930_002838"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFQ0519945.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1719..>4487
                     /locus_tag="ACG930_002839"
     CDS             1719..>4487
                     /locus_tag="ACG930_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFQ0519946.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKASTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFL"
BASE COUNT         1463 a          769 c         1018 g         1237 t
ORIGIN      
        1 tccagcgacc ctagatattt ttctgtataa tcttaaataa agaaaacaat atcaaaaaat
       61 gcacgtagaa gtagataaat ggagtggttt tgcaaatttc ttttatttct agaagttatt
      121 cacgtatacg gatttgtttt tctcacaaat aaaaaggcag gaagtacaat ggatcatttg
      181 tatataaaat atattcatca attttccgtt ttggtgttag gcacactaat tatagcgggg
      241 attgtcgcat ttattattca aggccgtgac atattaacag tacatcaaga gtttttcagt
      301 tatgcatttg gtattcctct gatcgctata aggtctgata acaaaaagtg gaagaaacgc
      361 tattacattc tcttgctatt tttgtgtttt tatctgccac ctaagatttt tactttatta
      421 ggtatacaat gcctatcatt ttcttttatt tcctatatca ttgttttaat tttcctcagt
      481 ttcatagtat ggatgtttta tcttgtcaaa aaataaatga atgtttcatg aacagtactt
      541 catcacagcc taattttttt ctttatgcta tcgttatatt aaagaaatca atcagaaggg
      601 aaagaaagtg atgaaaaaag ttttattagt ggtaaacccc agttcaggcg gtgaacaagc
      661 aaaggaattt gagcaattag cgatagcaaa attggaatcg gtgtttgatg aagtggtcgt
      721 cttgcataca aaaaaagcag gggatgcaaa aaactttact cgcgaagcgg ctacggaagg
      781 gtatcatagt gtgtttgtca tgggcggaga tggaacagtc aacgaaggaa tcagtggaat
      841 cgctgaacaa gaacatcggc caaatttcgg atttttccca ttgggtacgg tgaatgactt
      901 ggctcgagca ttagggatac cgctagaacc tgaggaagcg atcaatcatt tttcgattga
      961 atcagtcaag ccattggata ttggaaaaat aaatgacgac tattttatga atgtcgtcgc
     1021 aattggctct atccctgaat caatcaatga tgtagatgcg gagaagaaga cgaaatttgg
     1081 aaaactagct tatttcatgt caggaatcaa acagttagct tccacacaat cctactcgtt
     1141 tcacgtagaa gttgatggaa agaaggaaga aattgagagc agtaccttgc tgataggact
     1201 aactaactca gtcggcggtt ttgaaacatt acttccaaat gcaaaagtgg atgatggtaa
     1261 gctccatttg gtttatttaa aagattcttc tttgatcgat acgcttaaaa cattgccaga
     1321 cctattaaaa ggagtagatg aatctacgaa aaatctagcc taccttactt gtgagcaatt
     1381 agttgtgtca ttagctgatg aggaagaatt gacgacgaat gttgatggag atgaagggga
     1441 taaattacct gtgacaatca aagtattgcc ctcacattta caggtttatt gttaaaatgg
     1501 aggttgtgac cgaggagttg gcgggagaac accgcttgtt cgggataagg gactgtgaca
     1561 agacttttgt cacagccttt tttttgtaca aaaaagaaat ttacacctaa tagaaaaatt
     1621 tttccataaa aatacatatt ttaaatatga aagtacaatt ggaaatagat taaaacgata
     1681 aaataaaatt gtcaaaacgt cagagaggat ggtggagaat gaatcaatgt gtaaaaaagc
     1741 tgattgcgtc gattttgttt gtcttccctc tcttgatggt gacatccgtt tttgccgatg
     1801 tagagaaaac aaacgaatca acgcaatcag agaatcaaag ttttgacaag actacttttt
     1861 cagaagaatc gattacttct gaaactacag aatctcaaag tgaggcttct actaataaaa
     1921 ggcaagaaga aaataagaca agtgagacct cagaagtagc tgaacaaacg tctgatagca
     1981 gtgaagcggc actggcaaga gctgtttcag cggatgggta cagcgaagct gccacaacag
     2041 aagaactggc gcagcttctc gcagacgaat cagtaactaa gatccgactg attcagcctt
     2101 tgactttaga cagggaatta gagatcaaac gagatatcgt tattgatttt ggtggattcg
     2161 ctcacaattt cggcacacac catatttata tcaatgagat acctcagtcg atcgagttcc
     2221 agaattttaa aggaacagct gcacatccag gtggattgac accaaatatc gatggaaatg
     2281 ccattatcat tgcttatatg accgattttt ggggaagcag atatcatttt acgggagaaa
     2341 taaaatttac cgggacactt gatttgtatg atgggtccaa attaggactg atttacgctc
     2401 ctcgtgcaac tgtcacatta gatggtgttt ccggtgtgtt ggatgtccaa ccagtgaagg
     2461 aaggactgaa tgccgctccg ggtaaagcct atttttgtag aagctatcaa ttgaatgtga
     2521 tcaatggtag tcaactttat ggaccgtatc tagggaaatt ctacggtttt ctagattcag
     2581 gagatgagac tggtagtgga aaaacagcgc caggaatcca tatcttaagc ggttcaaagg
     2641 tctctcttga ttatgatcgg gcagatggcg ttagcgatga aggagaggca gtcgatacgc
     2701 tacctggtaa tgtcatgttt gaagtcagtg gttcgggaag cgaattttcg gtaaatacaa
     2761 agatcaatat taccaatgac aacaatcgcg gaatcatcca aatgagaggt tcaggatcga
     2821 aagtcactgt atcgaatggt gggaaaatca ccatcaatac agcaactacg ggcggatttc
     2881 gcttgcaagg agattctagt caaatccatg tatcaagtgg tggacaaatc tcggtcaaaa
     2941 tggctggaga tgacgatcaa cccgggaaca atgggatgcg ttttgtagga aaaggccttt
     3001 ctttgatcgt agaaggagcc ggatcagtta tcgacatcga taagcagagt gggcgttcca
     3061 gcgcagttcg ttttgagaat ggtacgcaaa agctgacagt aaccaatgga ggctcattga
     3121 gggtaagaaa tacaggtgat ggcaaatctt acgtgaacag actcaatcaa ggaaatcaag
     3181 cgatccaatt ttatgacgct tctggttttc tagaaagtcc aggttcagct gattttacag
     3241 tcactggaga aaaatcaaat atcgatatac gcgcagattc cggagcaact gtagatacaa
     3301 ctggagatat tgatttaaat tttacggcag gtgaaaaaac ttatttagtc atggtcggga
     3361 aaacagggga agataagacc ggcatcatca gtggggatgt gttgaatgtg gacttagaat
     3421 ctcctaccta ttttgatttc caaaacaaac ggattggaag cgagaccaat ggcataggcg
     3481 gctgggtatt ccaaggaaat ggagattctt ctttaaagat cgcccattca gaaatcgctt
     3541 tatggcgaaa aacaggcgca acattcgata actttgaaaa agacccggat tatttttctg
     3601 atatgacaga cttatcgatc aatgggaccg acttaggcaa tttcgtatca agccctagtg
     3661 caggtttaac aaatgaattt gctcagacag gtgccggaat gaaaaattat aatcgaatca
     3721 gtgccaataa tcagctcccg atgattgaat ccttaagagt gccaacgaat gcagataaaa
     3781 aaatctatgg gcatgtcgtt gttcccgaag gtgtcgaggc aaagccaaga gatgcttgga
     3841 caggcgaagt agaagtgact ttacgtatta cttacgcaga tacgacgaaa tcatctgtag
     3901 aaattactgc tctcacgcaa ggacaaacag atgaaaatga aggggcagga tataacccat
     3961 ggggagaagg cgaacaaggc ggcttgttcg aagttcaagt acccaatgat gagagattaa
     4021 aaacggagga tcaagtgcaa gttgttgctg ctaaaaaagt aagaggtggc caagaagtga
     4081 cagaactgga ctctgccaaa acgacagtcg atgtgattcc tcctgaacct gctaatttaa
     4141 gtaccacatt gatcaatgca gcttctcgca cgatcacagg tacaggtgaa gcaggagcct
     4201 tggtttcatt gaaaaaaaat caagctgttt tgtcagaaac aactattgat gatacagggg
     4261 aatttgttct ttctatccca gaaaatcaac tttttgcagg agatgtatta gaaattgtat
     4321 taaacgacca agcaggagaa gctactgcta agggtgtgca gaacaaggca agtaccaacg
     4381 atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat gccccgcctt
     4441 ttgcacctgc tacgaagatc gtagtagaag gtggtctctc atttctt
//
LOCUS       DAZKPE010000131         4310 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000131 DAZKPE010000000
VERSION     DAZKPE010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.135"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            102..554
                     /locus_tag="ACG930_002840"
     CDS             102..554
                     /locus_tag="ACG930_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519947.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            568..1257
                     /locus_tag="ACG930_002841"
     CDS             568..1257
                     /locus_tag="ACG930_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519948.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1382..3733
                     /locus_tag="ACG930_002842"
     CDS             1382..3733
                     /locus_tag="ACG930_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFQ0519949.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3813..4208
                     /locus_tag="ACG930_002843"
     CDS             3813..4208
                     /locus_tag="ACG930_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519950.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         1516 a          546 c          865 g         1383 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc ataaatttaa taagaaagcg aggtgagaat cgtgaaaaaa acgatactaa
      121 gtattttttc agtatttaca atattaattg ggggctattt tcttttgaat ttagattctg
      181 ttaattcaaa cgctcaaata aaagatcaaa gagtagctga acataataat aaaaaaatga
      241 gtttgaccaa aaatatctat tctatgtcag atgaagaatt gtataaagaa tttggtgatt
      301 tatccgggga acagttagaa gaaagtattc caggaattag tgactcagat aaaattgttg
      361 tcttgtctgc tggtgggcaa ttaatgggag atggcaaatc cgaattagtt agttataaac
      421 aaaatcacag acagtttatt gatgttaata ctgattccaa cgctatttcg attaaggatc
      481 taaaagagct tttaaatagt aaaagaaatg aattaaagca gataaaagaa actaattcag
      541 tggaattaga gtaaaggaag attcattatg aaaaagattt ttggtgtttc tgttgggcta
      601 cttatgatgt taacatttgg aaatgcagta tatgctgctg agaaagaagt tatttcagat
      661 ccagagcagt acgcctcacg atactttgct gattttgaag aagaagataa agtacttgca
      721 ttgccagaag gtggtttttt aaaaggggaa gctaaaattg tatctatgga taatccagat
      781 ataattcaag gttcatataa ttcagaaact gatcctgctt cagtttcagt gacagaagca
      841 aaaaaaattg ttgctgaaaa attcaaaaat gatattgaaa ctactccaat tatgcctcga
      901 ggagcatttc cacccgatgt tggtactagc ggacaccttc ttgtactagc aggaggagga
      961 agctataaat cacagccatt tagtggtgcg ggatggcgtt ttggaggtat gggtgtaaaa
     1021 ccagctgatg gtacaggcaa ctttttacgt tggaaatcct acattgacga tggaagagta
     1081 ggaaatgtaa atcaagccaa cgcaactaaa tctggttcta ttcaaggaat ggcattgtat
     1141 gctcgtgaag gattcaaata ctttgcacca aacgggcctg gttggacaat gaatataggt
     1201 atttattaca cttataatcc tgttgcaggt acgtattatg ttgttcaaaa tatttaataa
     1261 aacagcacaa agagatttct ttgtgctgtt ttattatttt tagttgttga caaacactaa
     1321 aatataaaat ataatcaaca cataaacgaa cgtatgttcg gcaagaaagc aggggatttt
     1381 tatggatgag atggttttaa gtactcagaa atggctaaac aagaaataca gtaatgttac
     1441 agggtttgat aaggttccag aaaatgggcg aacagggtgg cctacaatct atggacttat
     1501 tgaaggacta caagtagaac ttggtattac taatctagta gctaattttg gacctaccac
     1561 tgaaaaaatg tacgataatc aggttactcc taaatggggc aaaaatctac ctaaaaatat
     1621 tgtatttctt attcaaggtg ccttttggtg taaggggatt aatccaggtg gcttcgatgg
     1681 ggtatatact ccatatttag atactgctgt aaaagagttg cagactgatg cagggtttaa
     1741 tggaagcgct gtaactggag ttttggatgc gaaatgggcc aaagcgttat ttgatatgag
     1801 tgcttttgtt cttgttcccg gcggagatag taaaattaga aaaatgcagc aatggttaaa
     1861 tgtaaattat ttagaataca cgggaataat gccttgtgat ggtatttatc aaagaaattc
     1921 aaatcaagca ttaatttttg cattacaagc tgaactagga tattctccca gtgaagcaac
     1981 agggtcttat ggtaatggga caactagtaa aacttatcct gtgtctgaag gtaactcggg
     2041 aaactatgta agaataattc aatatggatt atatgttaat ggttattttg aagacggtac
     2101 attcgatggt attttcacta aatatatggg tttagaagta ctggcattcc gaaaatttat
     2161 ggtattgcct gaatatactg aaatagcaga tgttgttgta ataaaaggac ttttgtctag
     2221 cgctggagat attagaagat ctgcagatgg cgcagatact tctacgcaat taactagatc
     2281 tcaaatccaa acattggttg ataatgatat aaaaatagtt ggtagatatc ttactggtac
     2341 tgttggaatt ggaaaagatg aacgaaataa gtatctaact acagaggaat tgaataatat
     2401 tttttctaaa aatttatctg tgtttcctat ctatcaagat ggaggtgcag cattagctta
     2461 ttttacttat gatcgtggct tatcagatgg taagaaggct atagatgcag caaaaaatct
     2521 aaatatacca ttaacaacag ttatttattt tgctgttgat ctagacatgt taggggaaga
     2581 aattcttgca tatgctggag aatattttaa gggggtatct gctgtaatgt catatagcgg
     2641 gtatcaaacg ggtgtttacg gaacaagaaa tgtttgttct caaataatca ataacgggta
     2701 tgcttcgttt gcatttgttt cagatatgtc gactggttat agtgggaatt taggttttcc
     2761 tatgcctaga caatggtctt ttgatcaatt tgttgaattt accataggaa gtggcaacgg
     2821 agctgttggt atcgatttaa tcgctacatc gggtagagat agcggattta atgagttatc
     2881 aaatgatact aataatgata attacattgc caaatacaat cagaaggtta taaatcagat
     2941 ggtacgtgcg tatcaatatc tatcacaagc tggtcttgat aatccttgga accctcattt
     3001 gacattttat agatatgtaa attattctgg tttgtcatgg gacatcattt cttctcctgt
     3061 aacagagcat gatagaaaaa tttatgatga atataggaat aaattaacta atagcgaggg
     3121 cctgtataat tattttatag atcctaatac tggttcaata ataggtttgc ctcacttaat
     3181 tgtgacgtta caatcacaga tgtttctagc cgacacaatc aatgatagtg tttctgactt
     3241 tgcaggttgg ttaggagatt taatgacttg ctggggtgaa gttaagaaat taggaataca
     3301 aatggagcaa ggtgtatttg cattagtagg tacggctgca ggtggaacat ttagtctaga
     3361 agatttatac caagatgttg acgcggtaaa tgtttatacc ttagcaaaaa gaaattctga
     3421 ttcaacagct ttatcggctt taaaaacgta ctattgtgat aagggtgcta ttgatagatt
     3481 taatcaattt gttaagaaca gatttggttc ttcagataaa atcgcttcag taacaaatag
     3541 tttattagaa aatgacgaaa cagttgatat cttaggtgta gggataattt catttttcat
     3601 tgataaaata gttaataatt cacttgggac agattttact tatcttgatt ttattggaga
     3661 tgaggggaaa gttgcaaatg gattttctga aaaaattatt caatttcaag aaaatagaag
     3721 taaacttaat taagaatcgt ttactattta aacagtgtcc ttttcctttt taaatatata
     3781 cgataaaata agtatatgaa ttgtaaaagg acatgatgat tatggaagaa atagaatgga
     3841 ataatctgac tcaaaataat aaaaataatt ctggatgtgg aattatcttt atgtttgtta
     3901 tagttttggg aatagtagta cttttaataa ctgtcaagat agtagattac tttgcgaata
     3961 ctcctgaaga acaaatacag agaaaacttc ctgagtttga aagagtacca ccttatgatc
     4021 caagagataa ttcatttcaa gtaaaaaaat taaaagagtc tccaaatgaa atgtggtttg
     4081 aagttacagt tgaatcaagc gacttcaaag aaaaaaagaa agaatacaat tatattgtaa
     4141 aggcaaaagt atcaaaaaga tttattttta accctaaatt agaaatatat agtgttgtaa
     4201 tagaataata gtgttaaaaa aattgtaaaa gttaaagaag tcaaattctg atgtgaaaaa
     4261 taaaatatac catggaagac ataaaagaaa aactggataa ctagtttatt
//
LOCUS       DAZKPE010000132         4193 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000132 DAZKPE010000000
VERSION     DAZKPE010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.136"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..1357
                     /locus_tag="ACG930_002844"
     CDS             56..1357
                     /locus_tag="ACG930_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0519951.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1384..1644
                     /locus_tag="ACG930_002845"
     CDS             1384..1644
                     /locus_tag="ACG930_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFQ0519952.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2643..3878)
                     /locus_tag="ACG930_002846"
     CDS             complement(2643..3878)
                     /locus_tag="ACG930_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFQ0519953.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1208 a          674 c          873 g         1438 t
ORIGIN      
        1 ctttgcgttg tcatgcaatg aatggttcat attttattga aaaggagtgg ttttagtgga
       61 aaagctgatg aaatgggtcg aagagaaact tgtcccacca atggcaaaaa ttggtacaca
      121 gcgtcattta ttagcaattc gtaatggggt tgtttcaaca ttgtcattga ttttgattgg
      181 gacatttttt atggtcttta tcaatttacc gtttcctgga tggaatgaat ttattgcccc
      241 ttattcggca acgattgttt taccctttag gatgacgatg ggattgatgg ctatttatgc
      301 aacttttgtt atgggttcgg atctagctaa atcatatgga ttagatagtg tgacaggtgg
      361 tatattatct ttaggaacgt tctttatgtt acaagttcct gtaaacgttt taactcctga
      421 agaggcacct cttggctggg tcttacctat gagttctttg ggagcatctg ggatgtttgc
      481 ggggatctta tctatgattt ttgcagtgga agtatatcgt ttctttaaaa atcgaaatat
      541 tactatcaaa atgccagaac aagtgccacc tgctgttgcc cgtagttttg aggcattgat
      601 tccaggtgca gtcattttaa caattacttg gctgattcga agcgtcgcgg gctttgatgt
      661 aaacgctgcc ttattatcgt tattcgagcc tttaaccaat attttaggga ataatttgct
      721 tggtgtttta ctaccaatgt ttttgatcca tttgttgtgg tcatttggta tccatggcat
      781 gagtattgta ggggctgttg ttcgtccaat gtggctgatc atgttggatg agaatgcaaa
      841 ggcattggca gatggtacag ctgccaccca attaccctat atcgctcctg aacagtttta
      901 tcaatggacg gtaacaattg gtggtgcagg agcaacgatc gtggtatctg ttttgtttat
      961 attcttctgt aaatcaaaat tcttgaaaga ggttggtcgt ttttctatta ttcctggtat
     1021 cttcaatatc aatgagccca taatttttgg agctcctatg atgttgaatc cttacatgtt
     1081 catcccgttc aacttagttc ctttagtttt gactattatc agttattttg cagtcaaatt
     1141 agaaatggtc aatagattta ctgttttgcc aacatggaca ttaccagctc caatcggcgg
     1201 ttatctttca gcaggaaatg actggcgtgt tgttatcttg atcatgatca acacattgat
     1261 agcatttatt atctattatc catttgtaaa agcttatgat aaaaagatgc tgtcagatga
     1321 acaaagtcgt ggagaaaacg aagtccagac tgtctaagtt tggtttttag aaggtgggaa
     1381 acaatgtatt ggctgatttt attttttgtt tttatctttt tattaacggc tagtcacctt
     1441 atattgaata tgctagctac atatcatatt caaatcaatc gatggatttg ggcactggca
     1501 tcatttttga tcgtgattct tccaaagatc attgtaccgc atatgaatgt tttgttttca
     1561 tgggggacat atgtactttg tggaattttt gctatcaatt ttatgatcga gcagcataga
     1621 tggtttgtca catcgaagct ttaaatgttc taaaagtggt tgtaacagaa gtggttagct
     1681 tcaagaaata agaagaaatt tacgaaaatt gcttcttaaa tttttgtgaa atgttggctt
     1741 atttttcgtt tggttgaact tattaccgca gatgcaagct tttgaccacc gtttattcgg
     1801 aatatgggac tgtgacaagg cttttgtcac agcccttttt tacataaaga ttattattgt
     1861 tttaactgtt ttggcagaaa gaaggaggaa aaaatggaaa ttttatcagc aatggattta
     1921 gaattagtag atctactacc aaagtgatca agtcaaatat agatttggga gcttacaacc
     1981 atatagtagg ggctgcagta tggtgtatga atggtaatat gtatgatgtg agtgtttatt
     2041 caaatcatga aacgtgtata gaaataattg tgctgggaat agcaatcagt catggtgaac
     2101 gtgactttta gtgtatcgtt gctgacgaca tagaacattc tgacatgatc tactcaatat
     2161 gtggggattg ctggcagttt atataggagt atgcatcgga ttgcgagatc attgtctcaa
     2221 cagaagaggg aggttgatta tcaaagataa agtggtaaat cctacatttg atttagtaat
     2281 tgttgagggg actagcggca caaatctcta caaagcgatg cttctagatc tatatgacac
     2341 attttaagaa aatgtatttg cctaattatt atggtctttc ttttgaagaa acgttgagat
     2401 gatccaacca gagaaaggtg tcaaagaatt tgactaagaa taaatggcag acgctaccta
     2461 tgctcatttg gatagcgtca gatcttttat tttaaggatg attttgtgtt ttttagacac
     2521 cgtaatttaa gtaactctaa cttttcaatc cactatttac tttttttgta ttttcactgt
     2581 ctgggtctcg aatagcgaaa ttactgatga gtctctatta aaaaagcttt ttctacttga
     2641 aactatattg ggtggttgct caggaaggtt tcgatttctt gaattgcttg ttgtggacca
     2701 tttattggaa aaacggcttg cagcgtgcgt gcctgctgac gaatcttggg tgaagaaact
     2761 tcgcgcagag caatctgcag ttttctttca gtcactggtt ttgtgagggc gattgcgttt
     2821 ccgtatttta cacaatagtc aatattacag ctttgctcaa attgcatccc cacaccgata
     2881 aacggtttgc cggattcaca ggcagtttgg acggtccctt ccccgccgtg gataaaagaa
     2941 aaatcaatga attcatgcaa aagatgacta gacagatatt ctgttattaa aagatcttct
     3001 gagtcagatt gaatgtcatc aagcagatag tcaataggtg caataaccgc tagatccggt
     3061 tgtttttgta agaagaacaa aattttgcgt aacatacgcg gattgcctga actacccatt
     3121 gcgaaataga taatacgttt tctttcttgt tgctttcgct gtataaaagt tagcacttct
     3181 tcaggcaagg aagtactgag cttagcaaaa attggaccaa cgattcgata attttccggc
     3241 agctgttctt cttccaaaaa tagtttaggc gttgtgatga gatttagatc agcatccatc
     3301 atttgtaaac ttgtttttgg taaaggaagc atttcttttt gtgcagcgtg tttgaaggca
     3361 ttggggatcc atcgggtatt tactatacgc ttttttgtcc agtgccaaag gggattgctt
     3421 aaagggccga agaaacgtaa ctcgtggggc atcagcgcat gctctgattg aaaaaaaggt
     3481 tcactcaaag catagggttt aacatatact aaaggaatct ttttattgcg ggccgataaa
     3541 aaaattgtca cattcgaacc tgtcacaatc agtcgaggct caaacttagc aatcagactc
     3601 tgttcactag tgatacgaga ggcaaccatt tctttggtaa aagggttttt aagtgtacgc
     3661 aactggtcaa attttatgat ttgttcttct tgttttttcg taaggatcgg cgctagtaaa
     3721 tgatactcaa agccactttc tgtgatcaaa ggagcaaaag ttttagaaaa gccaaagaat
     3781 acacagtaat aacggtcttt catagctttg gcaacctcaa tcattcgtgt tgtctcagct
     3841 aaattgaata ctgcaggagc aaaaagaatt gtcttcatga aatcctcctt attggaatga
     3901 gtctatccct tcgtttctta ctagtatact aaaaaacaca gcgttcgagt agcctatgta
     3961 tattttgaat attaaactgt ctctcgctgt tttcacaact tctaaattta aattttgtaa
     4021 tcaagttgaa actccaattt tcaaaaaaac acgcaacaat tttttgatcg atttatatgt
     4081 tgtgccagat aaatacgaga agttgtgtca ttaaaaataa acatgagaac ataaaaaaat
     4141 aaaataatta tattaattga taggtgtgct gtcgtcatta tacacacgta aga
//
LOCUS       DAZKPE010000133         4192 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000133 DAZKPE010000000
VERSION     DAZKPE010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.137"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(71..313)
                     /locus_tag="ACG930_002847"
     CDS             complement(71..313)
                     /locus_tag="ACG930_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFQ0519954.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(345..902)
                     /locus_tag="ACG930_002848"
     CDS             complement(345..902)
                     /locus_tag="ACG930_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0519955.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(915..1103)
                     /locus_tag="ACG930_002849"
     CDS             complement(915..1103)
                     /locus_tag="ACG930_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0519956.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1116..1682)
                     /gene="amaP"
                     /locus_tag="ACG930_002850"
     CDS             complement(1116..1682)
                     /gene="amaP"
                     /locus_tag="ACG930_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0519957.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2099..2272
                     /locus_tag="ACG930_002851"
     CDS             2099..2272
                     /locus_tag="ACG930_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519958.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2912..3385
                     /locus_tag="ACG930_002852"
     CDS             2912..3385
                     /locus_tag="ACG930_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFQ0519959.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3394..3621
                     /locus_tag="ACG930_002853"
     CDS             3394..3621
                     /locus_tag="ACG930_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519960.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1259 a          760 c          635 g         1538 t
ORIGIN      
        1 aaccgcagcg agtgtcgcta cggttctcaa atttgttctt catttcaaca taagtttttc
       61 ttcaatttgc ttataattta cgtgcaaaga atgaaacgac taatactaaa atgattgcac
      121 cgatcaatga tggaatgata gccattcctg caattgttgg tccccaagtt cctagtaaag
      181 cttgtccaat tgctgaacct actaaaccag caatgatgtt tgcgatgatc cccattgatg
      241 atcctttatt cgtgattgct cctgcaattg ctccaatgat accgccgacg attaatgccc
      301 aaataaatcc cattttaaat tcctcctaac tgacttctta cttcttattg tacacgtggt
      361 tcgttatttt ctttgacttt ttgtgcacct ttgcctacag cagattttgc tttatctgtt
      421 tggcgtgaag caaattgtcc tgtggatttt gctgcttctg ttactttgtc ttgtactgtt
      481 tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg caacattcac attcacttcg
      541 ataacatcta aatgtgtcat attgtttact tcagtactga tcaattcttt gatttggttg
      601 taaatatctt cgatgtcttt accgtattct acgatcacat ctagatccac agctacttgt
      661 ttcttaccta cttctgtatt gatacctgct gttacgttat ctgtgttgac taatttttca
      721 gccatatttg agaaaaatcc gccatctaat gtcaatagac catctacatc tttcaatgca
      781 taaccgatga ttttttggat gactttgtct tcataagtca attcaccatt catcatgcgg
      841 ttttctcctt tttcatttgc caaaactgat ccatttgttg tattcatgtt tttgttttcc
      901 atctttgttt cctcctatga tttaaaaaat tgatcaacta ttcctgactg tttcaaataa
      961 aaaccgattc ctgcgccaat tgctgtcatg attatgatca acaatgtctt gaaaaatcca
     1021 atcgttaacc ataaaacagc tagcagtagt ccaagacccc caaagataat agggagcttg
     1081 tatgctgaaa atagttcttt cattatttgg ccctcctatt ccactcgaga gtgcttgtag
     1141 tctcttgtat cttcttgttc ttcataaccg ctgtatgtga ctgccacttt gaccgtttct
     1201 tttgttccga gtactttagt tacttcttct tcgatatctt gcatcaatac acctgttttc
     1261 cctactaatg aagaagttcg tttcaagtct ccgttgacat ggatatggat tcgatttttc
     1321 gttgaacgta tccgtacttt aggtgaatga atgaactctt cttcgtgtaa atgggaacgt
     1381 accaaccctt cgatcgcttt tttgtcgatt gttagtttgc catcttcccg tttcataacg
     1441 aaagttcctc ttgactttgg atagaaaaga acgactagca agatgataat agcaagaacg
     1501 gcaaatacta cagctgccca gaaaatatat tgttgcatgt agtaattcgt taaagtaaag
     1561 aagcgaaatc gttccaattg ttcaggcata atatacggcg cattgatcaa cgcaatcgct
     1621 agaaatactg aaagtagcag taaactcatg ataacaccga ttatttttaa ccccttattc
     1681 attttccacc tcctataaac ttatttttac cctgtaaata actctaccga caatcacagt
     1741 atagatagcg aacagttagc atagcatcag taaataaagc gctaccaaac attgctggat
     1801 cataacggcg ttttattgcc agtctgatac tgaaataaca attgcttact tattctctat
     1861 ttacttttga ttgctggcta tacttaaagg atattattca agattaaaaa ttgcaaagat
     1921 tatgctcagt tattattaca agattctatt tatttattaa attttttcgg agaattaaaa
     1981 aatacaataa ataactttag ttactttaat gcgttcttac tttattttta tattatcatt
     2041 tttcttattc acttctttgg tttatactat tcttataaat aaaaacgagg tatgtcctat
     2101 gatgaaaaga ttgtactatt cattgatcat aacgattggc tatttgattg tatcaaatct
     2161 aggaaatatg gtatttggta tcagtaaaga attcagttgg actactacat tatgggaatc
     2221 tctattcttt ttcatcttcg tatttttgtt acaaaattat cgaaaaaaat aaacatgtgc
     2281 catctatctg ttggcacatg ttttaggatt tatggtactt tttattcggc aatccatttt
     2341 atttttctac ttcttcttaa tacctctaac acttttgatt tataaactaa tccaatgcat
     2401 ctacttgcgc ttattaagct atttcagcta gatagtacca ccccatgcgt caatgcttga
     2461 ttttcctttt gtataacatt gtataagcaa taaaggacaa ataagtggtg attacaccaa
     2521 accattgaat aagaaaaatt ctgatacgta aataaacatg aacttgaaaa aattaatgaa
     2581 tcggttagct actacgtagt tgtctttttt ctcatacagt tctgttaact tacacttctc
     2641 ttcgctagat aataaaaaat cctccaactg tattgtccaa tataatccca ggcatctaaa
     2701 ctagcattat agaagagaca cacatagaat ctaaaataac tggttttaaa tgtttcttac
     2761 aatcaaaaaa agctgttaaa tgcactccac accttcatac tctatcattt tttataaacg
     2821 atatattttt attgtttttc gataaaaaat agttgtttta caataattat tctgctatat
     2881 tttagctatc aaagataaaa gagggataaa aatgaaattt aaaacattgc tattaaaatt
     2941 tgtcgtttta ggtataagtg ccgtatttat tttgttcggc gtactttttt atactcagat
     3001 cgctacaagc gaaaaaggat tcaattttga ttggcagacc acattatttg tttctgtcat
     3061 ttactttgcc cttctcctag ggatcgttat tgcttatttc ttattgaaac tattgaaaaa
     3121 aatcgaagat aaccaagctt tttccactca aagcttaaac atactaaaaa aaatcgaacg
     3181 aaccattttg tttattggtt tcgccttttt tggcttactt cctaaattta tgaaagtagc
     3241 ggatttagac gatgctccag gtttgatgtt ggtaggaatc gctgtcgtat tcattccttt
     3301 tgcagtatac acattaacaa gcgtgctgga aaaactgctt gaacatgcga ttttacttaa
     3361 gacagatcat gatttgacag tgtgaggtgc gacatggcaa ttatcgttaa tttagatgta
     3421 gtattagctc aaaaaaaaat gagtgtgact gaattgagtg agaaagtggg cattacgatg
     3481 gcaaacatct ctattctaaa aaatggaaaa gcaaaagcca tccgtttttc cactctcgaa
     3541 aaaatctgcc aagttttgga gtgtcaacca ggtgatttgt tgacctataa aaatgactcg
     3601 aatactatac cagaagaata aaataaagta gaacaaacag taaataaaaa ataatctgaa
     3661 tgatagatgt gtgagacttt tagaagttat ttacgtctat tattcagatt ttttatttcg
     3721 attgaatacc gttttatcta taaataagat atgtactgac tcatacaaag ggggcctttt
     3781 cttctccatg tactatcact tttcctgata caactggttt cctgttacgt tgtagttgga
     3841 tctgctttta gtataatact ttattcattc caccagactg atagcagttt gagcagtcta
     3901 aataatcatg tagtattaca ggccattctg tttcatacct tgaagtgctt aaaacttcag
     3961 ctaatggccc attgtgttaa ctcttactcc attctttttt agtaagctcc catatatact
     4021 gtaaagcctt ctatatatta tgtcatgttg ctttttaaca tttactatgt agttttgata
     4081 aaatgatttg aataacagtg atggacaatt cttttttatt tttaacatta ttttgataat
     4141 aatgacagac tgtagacaaa agctgttcca aactcgtaac tcgagcttgg aa
//
LOCUS       DAZKPE010000134         4174 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000134 DAZKPE010000000
VERSION     DAZKPE010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.138"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..493
                     /locus_tag="ACG930_002854"
     CDS             <1..493
                     /locus_tag="ACG930_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFQ0519961.1"
                     /translation="IFRAIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELI
                     QMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQ
                     TSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGN
                     IDE"
     gene            486..1913
                     /locus_tag="ACG930_002855"
     CDS             486..1913
                     /locus_tag="ACG930_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFQ0519962.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            1915..2985
                     /locus_tag="ACG930_002856"
     CDS             1915..2985
                     /locus_tag="ACG930_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HFQ0519963.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            2972..>4174
                     /locus_tag="ACG930_002857"
     CDS             2972..>4174
                     /locus_tag="ACG930_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFQ0519964.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFI"
BASE COUNT         1419 a          509 c          666 g         1580 t
ORIGIN      
        1 aatttttaga gctataatta atcgttgtct gaggatgatt aaacttcccc caaaaattag
       61 acaccataaa tttgatttgt atcatggttc tcaatggtgg gctttgtcga aagaatgcct
      121 aacagaatta atacaaatgt atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg
      181 tatgtttgcc ccagatgaaa aattttttca tacacttttt tttaattcct cgttcaaaaa
      241 taaaaatgtt attggaggac cagatttacc acttgaattg aaaaatattg aagaaactac
      301 tttacaaact tcgaaattag caaatattca tattattgat ccttccatga acaaatggtt
      361 tgatgaaagg gatatagatc aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa
      421 atcggattac tctgataaac tattaaatag aattgataaa gaaattttga aagttggaaa
      481 tatagatgaa tagaatagta cctgttttag agaagagttt attaagtcga gatgcgtttc
      541 gagtaataaa tttaatcatt tgtctgcttt attttatgcc tagtactttt aatgtaacta
      601 atatcccgat gaaaatagct tttgcttggg gtggaattat agttttgtat gaggttttta
      661 taaagaaaaa tttttttaaa atgcgttttt cttggctact gattggagca atgattagtt
      721 ttatcttaac tataatcatt aacagagaaa attttttaat tccatctatt tataattttg
      781 gatatttgct gattactttg atagtaattt ttcctgcaga cttttcacaa agtgaagagg
      841 aaaaaaagaa aaaaatggtg tattttaata atgttttcat tatcataatt tttttagctg
      901 cgctaatatc tatctatcaa tttatttttt tgatttctta tcatgtccca acaggaacgc
      961 caggattact tgcaagacaa ggttttattg aacatcggtt atttggtgtc tatacaagtc
     1021 caaatgttgg agctatgttt ggatatactt ctattatttt aagtttaatt agtgtattaa
     1081 tttcaaaaat aacaaaaacg attcgtgttt tttatatgat gaattttatc gtacaaatat
     1141 tttatattac actttcttcg tctagaggtg cccaggtagt aatttgttct tttttagtat
     1201 tatttctttt gttgtttgcc aattcaaaat ttagaaagag cattagagaa gtactacctg
     1261 taaaaatcaa atggatggta agcatattat tagttctatt ggtatatttt tcttttggta
     1321 ctaattatgc taaggatttt ttagcaacaa ttcctgtatc gattgataga aaagtagaag
     1381 ttatagagtc aaatgaatca gataaaactc cacttccaga aaaagaagta atattacagc
     1441 attctagtga taactccgaa atttcagctg gtcgttttac gatttggaaa gctgcgctta
     1501 aagttataag accaactttg ttatttggtt atggagagac cgatttctat gggaatagcg
     1561 atgcaaaatt tttgaaaaaa gtagatcttg atactacaga tgtgaatgaa ctaaaaagag
     1621 cacatggaaa catgcataat ggatttcttc aagtacttgt atcaagtggt ataattgctt
     1681 ttatatgtat ctatgctttc tatgtgttaa atatctttag tttactcaaa acatttttta
     1741 gaagtaaagt gaattatgcg tttcttggta ttgttttaat ttttatacta tctattttta
     1801 tagatgaaat ggtggaggct catgtacttt tcaataagcg cgatgtcatt tcaattgttt
     1861 tctggtatta tttgggaagc atttcttact tgtatttaaa aaaggagaat taatatgaag
     1921 acagctttca ttgcttggac tcctttacat ttgattaata tattaaatgt ttatcaaaat
     1981 ttttaccgag aatcaaaagg agatttattt atttattctg aatttgaaaa cgctagaaga
     2041 tatagtgagc gtataaaaga attagggcta tttaatgatg ttgtttttgt gaatcaccgg
     2101 aaaatcggtt cttcctttaa acgtaaaatt aacttgttaa ctaaccataa tcaatttttc
     2161 tcggatgatt tatccgttta tgatgaaatt tttatacagg gggaaaatta tttcacaaaa
     2221 atacttttct ccaatgttta caaaaaaaat ccagatgtaa aactaaatta tatagaagat
     2281 ggtttgggta cttatttgaa gaagagtata ttttcaacaa gtaaaaacgt tcaaagagtt
     2341 tttaaaatat taaataaaaa tagcatcttc aaaaaaaaaa ttgacgatta ttttgtctat
     2401 tgtccggaat tgttacttta tgatgtaaaa aatataaaaa aaattcccaa aatagatgaa
     2461 aacagtaaat tgatgaaaaa catacaatca atctttggga tagaagaagt ttttgtcgga
     2521 gataaatgta tcttttttga tcaaccttta ttatctgatg gttatggcat agatgaaaca
     2581 gatattttcg ctaaagtaaa tagtatattt tctggaaaaa aagaaacttt aattaagctt
     2641 catcctagag caaggacaaa tcgttatggt gaaaaaaaca tattgaattc cagtttaccg
     2701 tttgaagtct tgctacttga aaatgacttc tcttcaacac ttttgattag tcctatatct
     2761 acaatttctt tttcaccatc tatgatgttt gaaaagacga tcaactctat tatgttggct
     2821 aaattaattt taaatgaata tacagcatta tctgaagata aaaaagaaac attgacaaat
     2881 attgttcttt tctgtgaaca ttataaccgt ctatcagaag aaaaaatttt actcccagaa
     2941 aactgggcag aattaagaaa gttggtagag tatgggatta tttaacacac tttccaagtc
     3001 aaaattagtt aagtccagtt tctggtatac tatagggaat ttttttatta agggaatttc
     3061 attcataact attcctattt ttgtaaatat tactactcaa gcagaatatg gtttgattaa
     3121 taatttcact tcatttgtat caattttttc gattcttgtt gggctaagcc taaattcggc
     3181 aattaataat gcaagttttg actataaaga tgacataaat gaatttatgt catcggtact
     3241 ttctctagct acactttcgt taattgtgtt cttattaata gggaacatat attttttgtt
     3301 ttcaaatgct ttttttgata tgaaccaact tgtatttaat ttgatgttat tacaaagttt
     3361 tgctagtttt gtaattagtt atatccagtc ttattttacg attaacttta accattttaa
     3421 atatttgatt ttatctttta tatctacttt tttgaatatt gcaatctctg tagctttgat
     3481 gcagacatta tattttgatg ataaatatgt tggcagagta gtcggcggaa cactgtcatt
     3541 tgtgttgata ggtttagtaa tttatttaag aataatgata aagggtgctc atttttttga
     3601 taaaaaacag tggagatacg ctttaaaaat ctctttgccg ctaatcccac attccttagc
     3661 aaatatagtt ttagcacaat tcgatagaat tatgattaat tcttatttag gtcctgctgc
     3721 ggggggaata tattcctaca ttagtaacat aggtattatt ctaagcgtaa tatggatgtc
     3781 tactaataac gcctgggttc catggttcta tggtgagatg agtaaaaata atgaaaaaaa
     3841 agtgaagaaa gttagtaact attatttagt agtctttact ttgattacga tgattgtaat
     3901 ggtagtttcg attgatttag caaaatttat ggctccgaaa gactattatt ctgggttatc
     3961 tttagtggtt ccgataacct taggctattt ctttcagttt ttatatagtt taccagttaa
     4021 tgctgaattt tatgagaaaa aaacatcgtt tattgcgatt ggtacagtag caagtgctat
     4081 agttaatata ctattaaaca tgattttcat acctaggtta ggaataattg ctgctggata
     4141 cacaaccgta tttacgtatt ttttactttt tatt
//
LOCUS       DAZKPE010000135         4159 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000135 DAZKPE010000000
VERSION     DAZKPE010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.139"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..1149)
                     /gene="nagA"
                     /locus_tag="ACG930_002858"
     CDS             complement(1..1149)
                     /gene="nagA"
                     /locus_tag="ACG930_002858"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFQ0519965.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1225..2061)
                     /locus_tag="ACG930_002859"
     CDS             complement(1225..2061)
                     /locus_tag="ACG930_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519966.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2245..3462)
                     /locus_tag="ACG930_002860"
     CDS             complement(2245..3462)
                     /locus_tag="ACG930_002860"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFQ0519967.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3611..3772)
                     /locus_tag="ACG930_002861"
     CDS             complement(3611..3772)
                     /locus_tag="ACG930_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519968.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3845..3928
                     /locus_tag="ACG930_002862"
     tRNA            3845..3928
                     /locus_tag="ACG930_002862"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3879..3881,aa:Leu,seq:gag)
BASE COUNT         1206 a          892 c          694 g         1367 t
ORIGIN      
        1 ttatgcgtgg aaacgttcca cgccatctag ataagttgct tccaatgtca tatcagggtt
       61 caatacgata aagtctgcat cgcgtccttg agcgattttt ccacatgtat catcgatttt
      121 acagctgatt gctggaatca gactagccat catgactgct tgttctggtg ttgctaatcc
      181 ccagtctaca acatttttaa ttgcttcttt caatttcaat atacttccag ctaagttgcc
      241 agattctaga cgtgctgttc cttcttttac tactactgga aattcgccta aattgtaatt
      301 tccatcaggc atcccaccgg ccatcataca gtctgtaatt aatgcgacat gatcatgtcc
      361 tgctttttcc attaggattc ccgcagcatt tggatgtaca tgatggccat cacaaatcaa
      421 ttcagaaaag acatgttcta aagataataa cgcacccacc atacctggtt cgcgatgatt
      481 caatccacgc ataccattga aagcatggac aaatacactt gcgcctgctt caacagcttt
      541 ttgcgcttct tctagtgtag cattactgtg tcctagagaa acaactactc cttcttcagt
      601 cacttgtttg acaaactctt ctacaccttg acgttccggt gctaaagcaa tttttttgat
      661 taaaccacct gaagcttctt gccattcatg gaaagtatcc aaatcaggat ccccgaaata
      721 acttgggttt tgtgcccctt tgtgttcttc tgtgaagaaa ggaccttcaa aatagattcc
      781 tttgatttta gctcctggtg cttcctgata cattttgccg attgtctcag ctacatcttt
      841 taaacgttct ttgcttgacg tcaatgttgt tggtaaaaat gaagtcactc cacaagataa
      901 cagaccttca gacatcactt tgatgccttc tgcatcatta tccattacat catgattcat
      961 atagccgtga atatgtgtat ctaccaaacc aggagcaatc catttgccgc tttggtcaat
     1021 gatgttgact tctccctcag gtagttcttt ggtgtattca ccaaaaagtc catcggtaat
     1081 ttcaagatag cctgcatgtt tgacacctga cgctaaaaag aatttgtcag catagataaa
     1141 agttctcatt ctattctctc cctttgtttt tctacctcta aagtactctt atttagagaa
     1201 gaagtcaaga atggtctaca ccatttacaa attttttgaa atttgtttca cagcttgtgc
     1261 taagccttca tagaatgctg ctctttctgg ttcttcttta cgcttgtata ttaagctttt
     1321 aagcacaaat aaatcattga ggtaatagta gctattcttc tcttgagccc aatagattcc
     1381 ttgattcacc tgttctaacg cttcgtcgat ttcattttga tggaataaga aatttccata
     1441 attataaaaa atttgcgaaa attcactttt tgatcgttca tcagctgatt gatgcagcag
     1501 ttggatgctt cgactcaaat agtagcgtgc ttcagccgtt tttcctgcca caccatatat
     1561 ttttccgata caactaatca gttgtatttc tgtgtcagaa acatggattc tttctttttg
     1621 gctagagtag cttaatgctt ctttcaaata ataaagggac tgagagatat tttgacgcaa
     1681 cgtgaattcg caaacaccga gataataata atagcgttga aagtcagttg cttgatacag
     1741 attttcagaa atatcagaag attttagtac ttgttctaac ttccgataat cacgtttttg
     1801 gaaacaacta tccaacagtt caaataattt atcgtttgtc cgagtagttt ttcgagagag
     1861 attcatcaca tgatcaatcg ttacccctag ccgttgacaa atctgcatca tcaccaatac
     1921 attcggcagt tcctcattat tttcgatccg acttaataca ctttgtgaac aaatatcatg
     1981 cgaaagcatt ttttgcgtca ttttttgttc ttttcgaatc tctttaatga tcgttccaaa
     2041 ggactcgatt aacgtttcca taagtatcct ccccaaaata tgcgtattcg cattctattc
     2101 gtattttact ttaggaagtc gcaaacttca agaaaagact tgcaactaaa taatatactt
     2161 tagttattta agaaaactcc actagaaaga gagcctcagt gtgtttgtct gtggccctcc
     2221 tactgaaaaa tttggttttt aaaatcattt ttggcgatag gttgctagga attctctcat
     2281 tttcttagct gtttgtttca aatcatccat tttaggaaga taaacgattc gaaaatgatc
     2341 tggctggttc caattaaatc caccaccatg tacaagtaga atatgatgtt catgtaaaaa
     2401 gtccaaaacg aatttttcat catccaaaat attgaatcgc tttgtatcaa tttttgggaa
     2461 tatataaaaa gcagcttttg gttttacggc tgaaagacca ggaatatcat tgattgcatt
     2521 atagatatat tctctttgtt catagatcct tccgcctggc aggagcagct catcgacact
     2581 ttgataaccg cctagcgcgg tttggataat ttgctgagac aatacattgg aacacaaacg
     2641 catggaggac aacatattca gcccttctat atagcctttg acgtgtgact tatctccact
     2701 taggaccatc cagcctactc gaaatcctgc tacacgatga gatttggata gaccgttcag
     2761 cgtaacaacg aacaaatcag gcgctaatgt agcaatcgga atatgttcta gaccatccat
     2821 cactaagcga tcatagattt cgtcggaata aataatcagg ttattttgtc gagctacttc
     2881 aacgatttct tctaataatt cttttggata aagtgcccca gtaggattat taggattaat
     2941 gataacaata gcttttgtcc gactcgttat ttttgatttg atatcatcaa tatcaggata
     3001 ccattctgcc tcttcatcgc aaatataatg aacaggtgtg cctccagcta atgcaataga
     3061 agccgtccac aacggatagt ccggcattgg aaccagtact tcatctccat tgtccagcaa
     3121 cccctgcata cacatcgtga tcaattcgct cactccgttg ccggtgtaga tatcattgat
     3181 cgtcacattc ggaaaatgtt tcagttggca atattgctca attgcttttc tagcagaaaa
     3241 gatccccttg gaatctgagt agccttctga gtcacgggca ttcatgatca aatcacgaat
     3301 gacttcgttt ggtgcttcaa atccaaaagg tgcgggattt cccgtgttca attttaaaat
     3361 actaatgccc tcttcttgca tccgctccgc ttcttctaga acgggaccgc gaacatcgta
     3421 actgacacct tctaatttgt tggatttttc aaattctctc atcacttagc caatccctca
     3481 tttcaaaaag ttagaacttt ccaaattttt tgttatttac tatttcaata tcatactcca
     3541 tcctagaaaa ttttgccact tatttaggaa aaacgtaagt attaaaaaaa cacaaacaag
     3601 cgttgagaac ttaattgtca tgatagtcat tccatagatt cgctgcccaa tccattgcaa
     3661 ttccacaaat gattcctagc ataaaaccaa gcaaaaaacg tccgaatgca agtccaatca
     3721 atacacctaa gatcattccc agtcctgaaa attctccgtc atatttctcc atcttaataa
     3781 gtcctcccat ttttgagctt gacaactatg taaaacctcg ctatcattag tgtgttatta
     3841 ttacgcagat gtgttggaat tggcagacaa gcatgattga gggtcatgtg agcgttagct
     3901 cgtgtgggtt cgagtcccat catctgcact acaactcgtg aagttaattt tgcttcacga
     3961 gtttttttgt ttgaacgttt ctttatgcca ttatatacat atcactgtat cctttacaaa
     4021 aagaacgtac aatcatgtaa acagcctgag gtgagtatat gaaggtcgga aacaagctac
     4081 tcgtagaaac ttgcaagtgt taaaacaatt aatcgaaaaa cgagtaaaat ccctcaccta
     4141 atactaaagc gagggattt
//
LOCUS       DAZKPE010000136         4147 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000136 DAZKPE010000000
VERSION     DAZKPE010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.140"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            50..388
                     /locus_tag="ACG930_002863"
     CDS             50..388
                     /locus_tag="ACG930_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519969.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            392..754
                     /locus_tag="ACG930_002864"
     CDS             392..754
                     /locus_tag="ACG930_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519970.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            975..2381
                     /locus_tag="ACG930_002865"
     CDS             975..2381
                     /locus_tag="ACG930_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFQ0519971.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPNLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELRYISRQREE
                     NEREKALVASERVKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            2828..3802
                     /locus_tag="ACG930_002866"
     CDS             2828..3802
                     /locus_tag="ACG930_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0519972.1"
                     /translation="MSKRGTIVNEWEKLNRISNRRLKYQSLTLPLKMQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     HEGKGRIDFNPNKINQFLSGSMKNFIHDLFLEPHFSRADIACDIVDIPDDFVSQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPPEITTWWRLELQ
                     LRRGKATDWHEMVHESLDSFASPHYFPPNTKVTERIMVKGLLYDHSEWGNLAKNTKKK
                     YRDLLKQESQNDELTNHLRESFAESADDLKRELDTWLQGLDVTEVGAE"
     gene            3799..>4147
                     /locus_tag="ACG930_002867"
     CDS             3799..>4147
                     /locus_tag="ACG930_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0519973.1"
                     /translation="MSNPVEKMTIKNLADELGVSKNTVRNQLVNSGFDLAQYKENGII
                     MLDKELIGVVRSIYRSKSDQLTGQLPVNNTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQ"
BASE COUNT         1445 a          602 c          928 g         1172 t
ORIGIN      
        1 aaaaaaacga tcagttgtta ctagaaaatc aagaattaaa aaatcgaaaa tggtggcaat
       61 tctggaagtg aggtgtgaca tggataaaat tgatttgaga gaagaaacag tcgatagaat
      121 tgaattgatg tatgaacggt tagctgatta tttgaatttg ccggatgaag ataattatag
      181 tgaaatgctt gaacgaatta tggatgttct caactcggtt atcaatgctg atttagcaaa
      241 atcttcagtt ttgactaatg aatttgttca taagcattta gcgcaaacaa ctgatgaatc
      301 agaaaaagaa ttttggttga aattaatgag tcatgttatg cagttaaacc aaatttccgt
      361 tattaattcc aaagaaaagg agatgtagtt tatgggaatg actttagcag atattaaagc
      421 gcaagaagaa aaattaaaaa aagaacaagc gaaacttcgc caacagaaaa aacgcttgat
      481 tgagaaagaa aatgctgcaa tgggcaaggc tcttcgcaag cgttttgggt ttgaaacttt
      541 tgctgatttt gagcggtggc tatcgtcgat ttctgacgat cagcaacacg aaaaatcagt
      601 ggataatgag tggcttgctg atgaaaaatc agcgccaagc gaacgagatt atcccgatga
      661 atctgacggc ttattcggag tgataccgaa taagaaaagt cagatgagtg agagtaaatt
      721 tacgtcaata tttaatgacg tgaatttacg ataagcgatt attttgcgtg aagcaaaata
      781 aagcgtaaaa ggagttgaga gcgtgacacg ctttcggctc cttttttcgt tgtcacttgt
      841 gacagcgaat accctcggag agcatttgga attgtgacag ccatgtcaca attaggaaaa
      901 tgttactctt tgacaaagag taacagaaag gtttacactc tttttattag cgacagccga
      961 aggagggttt taacttgggg ttcagtattt cgttcaaaaa gggaacaaag aatacaagca
     1021 tttctcataa taatcgtgag ttaactgata gccaaaaaat caatgactgg cataagcata
     1081 ttgatttcac aaaatcggat gaaaatatct atttagaaca aacaaatatt cgtgaaaaat
     1141 atgaagaatt attcggtgaa gccgtagaaa aatataatgc aaagcagaaa agagccgata
     1201 gaaaaatcga ggactattta gcaaaggttc gcaaggataa aaaattggaa ccacagcgag
     1261 aatttatcgt gcaaattggt actcttgatg attttcgtac tactcgtgat gatggttctt
     1321 ctactggcat atcggaacaa caagcagaac aaaatcgagt gattgccaac aaaattttag
     1381 ttgaatattt caaagaattt aaagaacgga atcctaattt atccgtctac aatgctgtta
     1441 ttcataatga cgaagtaagt ccgcacctgc atttgaatat tgttcctgtt gctgaagggt
     1501 ataaacgggg tgttcaaaag caaccaagtt ttaacaaagc cttgcaacag cagggtttac
     1561 gagcagataa agagaatggt cgagtgattt ggaataattt taggaatcag gaagttgagt
     1621 caattgaacg tttgatggca gattttggtt gggagcgtga gttagtcggt actaacaaaa
     1681 tcaaagatgt tcacgaatat aaagaaatca tgagcgagat ttcagaattg cgtcaaacgg
     1741 ccgtaaaaga gcgtgagagc gtttctgatg agttgaggta tatttctagg caaagagaag
     1801 aaaatgagcg agaaaaggct ctggtggctt ctgagagagt gaagattgaa gaagagaaga
     1861 aaaatatgct gaatgtaaaa aaagagatgg cggtcatttt ccaaaaagat attgttcctt
     1921 tagaaagttt caagaggctt cctgatggtt cgtatcattt atctgggaat gattttgttg
     1981 atttgtatca acgagctacg agagcaacaa atgccaagag aaatgctgat aacatgagtg
     2041 agcaatattt acagatgctt gagcaaaata cagaattaaa tgagtatgta gctacattgg
     2101 aagaagagcg tcatttgtct ggtagaaaac aattagcaga tttacaagtg gaaaataaaa
     2161 agctgaaaga agaaaatcgc tctttacgcc agcgtttaga gcgattaaaa aacgcatttc
     2221 aaaaatcgat cactcgtttg tctatccgtt ttggtcttgc agaaaaggat atggggcttt
     2281 ctgaggaatt agaagtgtta gagcaggaga aaaccttatt ttatcgtcaa aacgtctcac
     2341 agcgtaaatt agagcgttct gaagatgaga tcgagtggta gttacgatgt gcagtcaacg
     2401 gtaccggagg cggtttgtgc cgaggataag gagttgacgg ctaaaccact agcctattaa
     2461 gctgacattt gctaaaaaat ggccagtcca ttttttggcc aacctagcgt tagcgaagtt
     2521 tgggggcgcc cttttcaaag ggtgcggttt tattttttgg atatttgcat agctaaagag
     2581 aagtgctatt attgagttag caaacaaatg aactgaaaaa agagtaaaaa aatagtcgag
     2641 caacgctacc aacgttctcg acctttacgg aaactaatcg cactagctcc gtaacttctt
     2701 aatcattata cgaatatttt tagatttctt caagactaga gattttttgg taatgaattt
     2761 ttaagagtta cgtgaacttt tgaaaattct ttccagaagt ctctttttct ttgaggagga
     2821 acaaaatttg agtaaacgtg gcacgatcgt gaatgagtgg gaaaaactta accgcatttc
     2881 taacaggcgg ttaaagtatc aaagtttgac ccttccctta aaaatgcagt ggtcaattga
     2941 ccgaattacc atagtcggaa aactgaaaga aaatatttat tatcacactc caaatgatgt
     3001 gttgatttta aattttgaac agcttatgcg tttgaacgaa ggcaatggtt atttaaaagc
     3061 tgttgggaat aatgggtggc aattattaga ccaacacgag gaaaatatag cttatattga
     3121 gattcttaaa tttcatgaag gaaaagggcg gattgacttt aatcctaata aaatcaatca
     3181 atttttatca ggttccatga aaaatttcat tcatgattta tttctagaac ctcatttttc
     3241 acgtgcggat attgcttgcg atattgtaga tattcccgat gactttgtta gtcagtatcg
     3301 tgtagttgat cctgtgtctt ttaaaccaat ttatgggcgt tctggtaagt tagaaacggc
     3361 atattggggt agtcgtgcca gtgaacgaca aattcgaatg tacaataaaa aattggaaca
     3421 agaaagaaaa cgtaaaattg ttccgccgga aataacgaca tggtggcgac tagaattgca
     3481 gttacgaagg ggaaaagcaa ctgattggca tgagatggtt catgaaagtt tggatagctt
     3541 tgctagtcca cattattttc cgccaaatac taaagttact gaacggatta tggtgaaagg
     3601 tttgctttat gatcattctg agtggggaaa tctagctaag aatacaaaga aaaaatacag
     3661 ggatttgttg aagcaagaaa gtcaaaatga tgaattgacg aatcatttgc gagagtcatt
     3721 tgcggaatcg gcagacgatt tgaaacgaga attagataca tggctccaag gacttgatgt
     3781 aacggaagta ggtgctgaat gagtaatcca gtagaaaaaa tgaccataaa aaatcttgct
     3841 gacgaattgg gtgtatcgaa aaatacagtg cgcaatcaac tggtcaattc agggtttgac
     3901 cttgctcagt ataaagaaaa tggcattatc atgctagata aagagttgat tggtgttgtt
     3961 cggtcaattt atcggtcaaa aagtgatcaa ttgactggtc aattaccggt caataacaca
     4021 ggcagtgatt ttcctttaga aaaagagaat gagtttttgc gtgatcaatt agctgagaag
     4081 gacaaacata tttctgaatt aacagaaatg attcgtgatc aacaaaaatt gaccctgctt
     4141 cagcaac
//
LOCUS       DAZKPE010000137         4147 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000137 DAZKPE010000000
VERSION     DAZKPE010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.141"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(56..991)
                     /gene="murB"
                     /locus_tag="ACG930_002868"
     CDS             complement(56..991)
                     /gene="murB"
                     /locus_tag="ACG930_002868"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFQ0519974.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1064..1984)
                     /locus_tag="ACG930_002869"
     CDS             complement(1064..1984)
                     /locus_tag="ACG930_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFQ0519975.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2097..2849
                     /locus_tag="ACG930_002870"
     CDS             2097..2849
                     /locus_tag="ACG930_002870"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFQ0519976.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3346..3879
                     /locus_tag="ACG930_002871"
     CDS             3346..3879
                     /locus_tag="ACG930_002871"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFQ0519977.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1209 a          829 c          732 g         1377 t
ORIGIN      
        1 aagagcagga cggccaccgt cctgctcttt tacttatttt aagttccatt acttattaat
       61 tggctaaact tctgcttgtt tctgatattg cttgtttttc tccaatgatc cgcacttctg
      121 tttctaaaga cacatcaaat ttttctttga ttacttcttg gatgtgcgca atcaattcaa
      181 tataatctgt cgctgtcgca tgatcgatat tgacgatgaa tccagcatgt ttttcagaga
      241 cttgtgcacc gccccatttc aggccttgca atcctgcttg ttggatcagc tgacctgtat
      301 agtgtcctac tgggcgctta aagacacttc cgcatgaagg gtattctaat ggctgttttg
      361 attgacgcaa ttcggtcaac tcatccattc ttgctttgat tgcttcataa tcccctgttt
      421 gcaaactgaa tcgagcttcc aatacgatag cacgtaattc ttggacttta ctgtgacgat
      481 aagaaaatac catttcgtct tttgtcaaag ttttcaatgt tccatcttca agcaaaagat
      541 ccacttcagc aaaaacatct ttgatctctc cgccatacgc acctgcattc atataaaccg
      601 ctccaccgac acttcccggg atgccgcaag caaattcaaa tccagtcaat gattctgcca
      661 aagctgcata agtcgtatca atcagtgagg cacctgcttc cgcaatgacc atcgttcctt
      721 tgacatgaat ctgtttcatt tcagtcagca tgatgactac accgcgaatc ccgccatctt
      781 gaacgatcag attgcttgca tttcctaata ccatccaagg tatatcatgg attcggcaat
      841 aatcgatgat ttgctttact tcttcttgtt ttttcgggaa tgcaaggaca tcagctggtc
      901 cacctgtttt cgtaaacgta tagttcatca atggttcatc aaacaatata gtaatcgtgg
      961 ctaagctttc aactatttct tctttattca ctgaggattt tcctttcttt tctcaaacgt
     1021 cctcattatt ctatcacgct taatacaatc ttgccagtct tgttcaaagt tgatgacggt
     1081 agtgatcttt aagcacttcc tcacataatt catgacttct tacaacttct ttttgtttaa
     1141 gcaattctgt ttccgattta cctaaacgga tctgagaaaa gaaggcctct accattggct
     1201 caaacccgcg tttgactagc gtgtttgtcc agtcgccaaa ttctttcact ttttttccat
     1261 cagcatcttg aatgacaagc tgggtcagat cgtttacttc ataagtacca tttttacttg
     1321 ttacttgata tttttctata ttagcgccac ttgctaaatc catcgttaaa atagccgttt
     1381 gattttgtgt ttctaattgt aaaatggcat attccaaaaa ttcctttgtt tctcttatct
     1441 ggtattttgt tctcaaaatg ggttcatcta ataaatacac agctgtatca ataagatgta
     1501 aaaacaaatc ataaaggacg aactctgtcg tttcttttgc cgctattcga tttttttgca
     1561 ggtggatcaa ccgcttatct gggatacgtt tcaattcttc taccatagga gcaaagcgcc
     1621 ggttgaaacc gatcatcaaa attatttggt tcttatcagc taattcttgc aattcacgaa
     1681 cttcatttag atggacactc agtggtttgt caatataaac atggatacca ttttctagac
     1741 attttttggc taattcataa tgtacttttg ttgctgcgtg gatcatacat gcttcgattt
     1801 tttcttctaa aagctcatcg atcgtttcat atagatgttg gaacccgtac tctttttgaa
     1861 ttctttcttt tgtttcttta tttcttgttg caaaataaaa atcaagtgtt ccttgttttt
     1921 tcgcataagt tggtaaatat gctttttctg cgatattccc tacaccgatt acaccaatct
     1981 tcatctactt tcctcctgga tcatttagtt actttcatct tacaccattt tttactaaaa
     2041 tgaggtacaa tagtatcgca aaggtaagga aattaattcg aaggagtgtg cttttattga
     2101 aatttatctc ttggaacgta aacgggcttc gtgccatcgt aaataaaaat tttttagaag
     2161 tttttcatga gttagacgcc gattttttct gtctgcagga aacgaaactc caagcaggac
     2221 aaattgattt agatcttcca ggttattatc aatattggaa ttacgcggaa cgaaaaggct
     2281 attccggcac agcgattttt gctaaaaaac cagcattgaa tgccacttac ggaatgggta
     2341 tcgatatcca tgatacagaa ggccgtctga ttactttgga atattccgat ttctttcttg
     2401 taacctgtta cacgccaaat tctcaaagcg aattaaaacg tttagattac cgattagaat
     2461 gggaagaagc cttttataat tatttggaaa atctaaaaaa acaaaaacca gtcatcgtgt
     2521 gtggggatct aaatgtcgct catcaaaaga ttgatttgaa aaactggaaa acgaatcaaa
     2581 aaaatgctgg attcactcca gaagaaagag cggctctttc tcgactgttg gataacgggt
     2641 ttatcgatac attccgttat ttttatccaa cccaggaagg tgtctactct tggtggaact
     2701 accgattcaa ttcaaggaaa aacaatgctg gttggcggat cgattacttt ttgacgagca
     2761 aagatttaga gccaggacta gctgatgcaa agatccatac ggacattatg ggcagtgatc
     2821 attgtccagt agaattagat ttgaaataaa gaggttgtga aaaagctgca ctgcatcaag
     2881 taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg gacttattac
     2941 cgcagatgca agcttttgaa caccgtttat tgagaagttg tgaaatcagc gtcctgacct
     3001 gagtattaga gaaacaaatg gcaaaatagt tcctcatatt ttgctatttt ttgagctaat
     3061 accgagggtc agctgattga acaccgttta gtggagaagt tgtgaaaaag tcgcctactt
     3121 tcgagtcgta agaaattttt ttgaaaatgg ttcctcacaa ctttgcataa atttgactta
     3181 ataccgagaa gtcatgatcc ccatctaact ccaaatcaca aggaatgagt tcaaaaacta
     3241 gcttttctca acaaatatta cataaaaaat tctatgtttt ttgttaaatt tatttgcttt
     3301 tttcaaaagt atgttacagt aatttcccaa ggaggtttta cagaaatgaa ttttgttgcc
     3361 atggattttg aaactgccaa tcatcagcct tatagtgctt gttctcttgc gctagtcatg
     3421 gtaaaaaata gccagatcgt tgatgaattc tatacattga tacagcctga gactcctttt
     3481 ttctggcgaa atgtccaaat tcacggaatc catcaagaag acgtacgcaa tgcgccgaaa
     3541 ttcccagaag tctggcaaac tatccaacca tattttcaaa aaaatcgttt agtcgttgca
     3601 cataatgctg cttttgatac aaaggtctta gcgggatgct tagattatta tcatcttgaa
     3661 cagcctaatt atctttcttt atgtacagtg aaaagtagcc gtcgcctgtt tcctgaattt
     3721 ccaaatcatc gattgaacac tgtgtgcgaa aatttgaaca tccaattaga tcatcaccat
     3781 gatgcattgg aagatagtcg tgcatgtgcg gaaatcctgc tttatcaaga aaaaaaattc
     3841 gggacagatc cattgaaaaa acttgtgact ataaagtaaa agaatactta tgaaacacac
     3901 aaagaggtcg tgagcctgcc gtttcactcc gagtcacaag gagcaatttc aaaaaatagc
     3961 ttctcatgtt tattaaatat tgtgactggt gaccgaggag ctggcaggag aacaccgttt
     4021 attggagagg ttgtgaaaaa gctgttctgc atcaagtaat aagaacagcc aaacaaaaat
     4081 agcttctcat atttttcatt tggttggact tattaccgca gatgcaagct tttggacacc
     4141 gtttacc
//
LOCUS       DAZKPE010000138         3969 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000138 DAZKPE010000000
VERSION     DAZKPE010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.142"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(617..1174)
                     /locus_tag="ACG930_002872"
     CDS             complement(617..1174)
                     /locus_tag="ACG930_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519978.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1353..1964)
                     /locus_tag="ACG930_002873"
     CDS             complement(1353..1964)
                     /locus_tag="ACG930_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519979.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2077..2334)
                     /locus_tag="ACG930_002874"
     CDS             complement(2077..2334)
                     /locus_tag="ACG930_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519980.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2931..3209)
                     /locus_tag="ACG930_002875"
     CDS             complement(2931..3209)
                     /locus_tag="ACG930_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519981.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3243..3494)
                     /locus_tag="ACG930_002876"
     CDS             complement(3243..3494)
                     /locus_tag="ACG930_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519982.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1201 a          814 c          526 g         1428 t
ORIGIN      
        1 ctccttctta tttcttggag ttaaacgctt ctgtcccagc ctccttattc cgaataaatg
       61 gtgtccaaaa gcttgcatct gccagattat ctcatttctt atgacaagct aagcaaatta
      121 tctccaccaa ataatttatt catatttttg acttgcgcat actaactaat tcttaaattt
      181 tcatacaaaa tttctcaatt tcccttaacg agtaatattt atgtacggtg attctcacta
      241 gtatcccaat cactttttaa gttatcccga tttcaattct acttcaaaaa tagttgcttt
      301 tatgtatgct gttagttgat tagatggtca tttgttgagc taggtcgttt attttaaaca
      361 agttgtttct ttagcttata cctatctcgt ctaccaaacg caagatggca aacacaaatg
      421 catacgcatc tgtatttgcc actttgattc gtataaagct aacaactatt aactcctctc
      481 agctaatagt tgctctcttt tttattcaga ttcatttttg ctgatcacag cctagtattt
      541 caatggtttt gaacactaaa ccaaattgtt ccattacaac attcactggc tgatgaaatg
      601 gattagtaga tttcgattat tcaaagcgat tttctattgg tggatcgtgt tcccaactaa
      661 taagacggat tccaaaccta tcgtacagat cttctaaacc acttataaat tttgcaccta
      721 tttcaggtgt tttattgcgt ggatattcta ttgttacgcc attaaatgga taccaattag
      781 gattaggctc tctttttttc tgtacatctc ccatagaata gttagcactt tctgggacat
      841 aatatattct tcgaccatcc tctaattcat ctaataagat atttcgtgat cgtctatcac
      901 ttgctaaatg tagacgccac gtgcgatacc atgccatgct acctgcatct gcagaaaatc
      961 catcaaataa tgcaacaatt gtatcttcta tcacaatcct ttccccatct acttcatatt
     1021 ctaatctaaa atcaaactcc cctcgggtaa tttctggtct tggtggctta ggacccaata
     1081 ttattctact taaaaccgca ttcgttccca gatgaaacac agctataaca acaataatga
     1141 ttaatatttt gtttctattt gataaatttc tcattattcg cacatcacct ctacattctc
     1201 acatattagt tcgtaatact cctttaatat caaaatatct actggtcgta ataatattcg
     1261 ctatgaattc ctactactcg tataagaaag gccaaatcat cagcttttac ttgctgatga
     1321 tttggcttgt ttctatttat cgtaattgtt ttctaatcac caaaattgtt aacaatcggt
     1381 tcagatattt cccagttgat taaggtaatt ccgtattgtg tcaaaacttc ttgcgcttct
     1441 ccgaaattaa gtacagttct tatgtatcca ctttctccta atataaagtc tacctctctt
     1501 ttaaaacctt cctcgagatt tctaagggct atatgtggtt ttaatgacat tgattgtaca
     1561 ttttccccca tataatattg cgcacttcct cgactaaaat agattcctag atcgtcccca
     1621 aaaggtagat cttctctacc actagctaat ctacttctcc atcttcgttc tcttttcata
     1681 gaacctgcgc tgaactcaca cccgttaaac tcagctatga cagtatcttc aattatgtta
     1741 atctgtccat ctagttcgta ttcaatccta aatggaaatt ctccataggt gatttccggt
     1801 tcgggtattt taggtgagat taatgcaaag aaaggaaata ttaagcttgg caacatcaaa
     1861 aaaactcctc ctatgatcac aattcccgat gtaatccaaa atataatttg tacaattctc
     1921 attgatccat tgtattccat tttattcccc ctattactat tcatatccgc ctatctatat
     1981 cgatcttcca atgcagagat aattgcttcc ataccttgat tttttactga gttacctatg
     2041 cgagatatca ttctccacta aggtgcatca tattgtctat ctaacatgat taattctcca
     2101 ataggtgtat actcctccaa aaacaacatt taatgcatct ccctcgacaa cataagctac
     2161 catgtttgct gtatatgtgt ttgagtctaa ttcataagca gataaattta ctgtcgctgg
     2221 attaaatata atcgcattcg tatttatagc tactgaattt gctgcttcag caccaccttt
     2281 tgaatgtccg atcattgtga tttcaatagt aggatttacg tggacagccc tcaccgttta
     2341 ccctgaccat tatagaaatc gcttactttt ttgaactacg caacaaagga tacaatgctc
     2401 ctaacttcac tgtctccatt tttgtccact aaggaatata aaaaataggc attaattcat
     2461 ttaattcggt cacaacacgt taccttttaa atcattatac tgtatctcat acattattat
     2521 caataaacta ttataaaaat gcaaaaaatg ctttatcaat ctattttgta attggtcata
     2581 atatcattga aatcataccc tgtatcgatt tttcctatga atctcgtcta tttgtgattg
     2641 acgaaaaaga ggcaagacag acactggaat ggtaatttta cccactattt tgctccaact
     2701 atttgtaatc gtacccactt ttgaaatacc gagatgatca ttttaattga tatgctgatt
     2761 cccaagcaaa accccaagaa attaaatgct ctatcgcatc tagcttcttg ggttttgctt
     2821 atataaattc caacatttaa attttttatg ctgttcggtc tcagaaatgc cgtttttgct
     2881 tatatcacaa tatcaagatg tcaaattatt cgtgttgccg atgactttga ttaatttttt
     2941 tcaaattgtt tattaagact aatgctgtct ttttgcagat accaatgttc gaacttttta
     3001 acattatcat atgatcctgc aagttttaac ttcttaccat tagatgttat caaagttata
     3061 attaaccttg cctttttccc attaggatct tttattttat gaattttctg caggtaatct
     3121 ctcctaatgg cagctatttt tacctcatca gtgctgataa accattgatc atccacatac
     3181 atactgcctg ttatgttgtg tttttccatt tcttccgaga acgaaaagtt taaggctcgt
     3241 tcttacttcc aaagttgaat gagtccatgg attggactta gtgtgagaat tgagaacaac
     3301 aataagaatc catatcctcc cgcaaacatc cctaaggcta tactgtctct ccatccataa
     3361 gtaggattag aagagaaaag agtcaccgtt tgtaataata tgaaaaggaa taatccagca
     3421 caaacaccaa agataacaac tccaaacatt gaatttttat acaatgacca tttatttata
     3481 ggcttttctt tcattttact tccccctact gttctgttca cacggaatga attcaaagtt
     3541 cataagccct cctctttgaa catatgaata cgacttgcta actatacttt aaaaaagctt
     3601 gttttaagcg gttataggcg agttgtaatc tctattcatc tcattagcaa ataacttgcc
     3661 gaaaagtcta ctgaaattaa agcagatagt ggaagaatta tttagccagg atagacacta
     3721 tttgtgaaac acatgtcttt acttttgaaa ttctatgatg aaaagccttg gaatacagta
     3781 gctcttaatt ggtaatactt tttccattat aaataacctc ttttcatttt atatttatcc
     3841 cctctaaaaa taatatctaa tctaatattt taaacttata tttccctcgc tgtgctaata
     3901 gagcattact aaataaatag aaactagaaa aaagcattac gcctgccaga ataaaccaat
     3961 tatttgtat
//
LOCUS       DAZKPE010000139         3964 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000139 DAZKPE010000000
VERSION     DAZKPE010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.143"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(133..558)
                     /locus_tag="ACG930_002877"
     CDS             complement(133..558)
                     /locus_tag="ACG930_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519983.1"
                     /translation="MGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMASIVGIG
                     FAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIYLLHILV
                     FSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(664..1074)
                     /locus_tag="ACG930_002878"
     CDS             complement(664..1074)
                     /locus_tag="ACG930_002878"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFQ0519984.1"
                     /translation="MISFEKAFSIFAIVLMYYFQQSYLPAILNKAISIGDTGVHIFFF
                     CSGFGLYLSYLKKPITLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSH
                     VLLFKIFLPVYEESLGPFGLFRQLFSSISYSYQL"
     gene            complement(1373..3025)
                     /locus_tag="ACG930_002879"
     CDS             complement(1373..3025)
                     /locus_tag="ACG930_002879"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFQ0519985.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            complement(3085..3225)
                     /locus_tag="ACG930_002880"
     CDS             complement(3085..3225)
                     /locus_tag="ACG930_002880"
                     /inference="COORDINATES: protein motif:HMM:NF016763.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFQ0519986.1"
                     /translation="MIKFVFLCSCLIEFLQLFLHIETFQLSDLFYNTLGGGISGVIYY
                     LS"
     gene            complement(3219..3575)
                     /locus_tag="ACG930_002881"
     CDS             complement(3219..3575)
                     /locus_tag="ACG930_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519987.1"
                     /translation="MFLYLFAMAEEKSGLGLKKSFLVWIRYFRKSSSFRKMFLLVFFT
                     NMILFRTLMDRYVWLNPLSNVFGSWWIYSVNETTGEIRLTTECFENVILFIPFIILVM
                     WYKASEKDFGKIYQRL"
BASE COUNT         1298 a          907 c          639 g         1120 t
ORIGIN      
        1 aatcatttag ttttatctcc tttttaccaa ccatctacca ctaggttacg aactacctaa
       61 gtgcccacca tccgccgcgt ggaggctgtt aatcaggatg gcaaccgccc ggtagaggcg
      121 acaattatgc tatcatttta atttaagtct atataacata atactataat aatatgacaa
      181 caccaacgtt ataggaatgg aaacaaatgc cgccaaaacc aagttaggga taatttgatg
      241 aatcgtacta aatacaagaa tatggagtag atatatatca tatgagtatc ttgaaatcct
      301 aggcattatc tttctaaatg gaataacttg atacattaaa attgcaattg caccgtaacc
      361 gaagaatgca aaaatatcat taatagactc catcagtcca ccaataattt tcgatatacc
      421 agcaaaacca attccaacaa tggacgccat aatcacgaat atattattaa atcttactat
      481 ttttcttttc actaaatact ctgcaaccaa acatgccgaa agtaaattcc caaatatatt
      541 gcgcaaagca gctcccaaga actcgtatgc ttccatatcc tgtatgaaac atcataatag
      601 cccagatact aataactcag cttgcaacaa gcaatcattt cattcctatt tttctctata
      661 gttttacaat tggtatgaat aagaaataga actgaataat tgtcgaaata aaccaaaggg
      721 acccagtgac tcctcatata ctggtagaaa aattttaaat aacaaaacat gagacaaata
      781 tacttttgca gcatttaaat cttgtgtcat ataaggtagt aacactgata ccgtaattac
      841 gataatatac ggaatataaa tcttgataaa tcgtttctgt aaaaattcac ccaatgtaat
      901 aggctttttt aaatatgaca gatatagccc aaaacctgag caaaagaaga atatatgcac
      961 tcctgtatca ccaatagata ttgctttgtt cagtattgct ggcaaatacg attgctgaaa
     1021 atagtacatc aatacaatag cgaatattga aaacgccttc tcaaaactaa taatatcacg
     1081 tttatttctt tccccctcat tttattattt caatagtttt attcatattc tactcctttc
     1141 atctctattg ctgaatacat tattaaaact ctaatatctc ttatttctcc cttactgctt
     1201 tgatcggtgc ttcatcaggc tgctgtgtct ctgttaacac ttctttgcct tttcgatcca
     1261 cacagtcggc ccctttacct caattatgta aacagaaccg taaagcagga aatttttatt
     1321 aaacatagat gttgctactt cggacattga cactcagatc tttttcatag tattacttaa
     1381 acatttcagc cagttcagca gccataacag cttccattac ttcggcagct tccttgcttt
     1441 ctgcgctaac gctgatatag gtcttcagct tcggctcagt gccggaaggc cgaaccacta
     1501 cagagcagtt gccctccagc agatatttga gaacatcaga cttcggcagg ccattcagtc
     1561 ccgtgctgta atccaaggtt tcaatgacct tcttacctcc aatcatatca agacctttat
     1621 ggaattcaac cataattttc tgcatcttgg taaaacctgc cgcaccctca aactcaaagg
     1681 aatgcagggt gttcaaacag tagccatact tagcataaat ctcgttcagc ttatcaaaca
     1741 gactgatacc ctgagtcttg tagtaagaga acatctcgca gatcagataa gcggcgttga
     1801 caccatcctt gtcacggaca tagctgccgg atagatagcc gtaggattcc tcaaagccga
     1861 aaatatagct gtccaccttg cctgcctttt ccagcatacc aatctgttcg ccgatgaact
     1921 tgaagccggt caacacatcg acagtacgca cgccatagtt ggaagcgatc cgctcgccca
     1981 gatccatagt cacgatggtc ttgaccatca cagggtcagt gggcatcttg ccgtgcttaa
     2041 ttctctgaga gcatatgtag tccagaagca acagaccagt ttcgttaccg gacagcagga
     2101 cataatcccc ttctgcattc ttcacggcga tacccacacg gtcgcagtca gggtcggtag
     2161 ccagcagcag atcagcatta tacttcttgg catactccat gcccagagac atagcttcat
     2221 taatttccgg attcggataa ggacaggtcg ggaaattacc gtctggcaga cgctgctctt
     2281 cgacaacggt cacattgctg tagcccattt ctgccagagt acgggtaaca ggcaccagac
     2341 cggtaccatt caaaggagaa tacacgatag caacattctt gtccacttct tcgccaaaca
     2401 gaaccgactg gccctttact tcttcaatga aagcagtcag aacctctggc tggatagaag
     2461 cgattctgga agcgtcgccg cccattttca catctgcaaa aatatccagc ttttcaattt
     2521 cagccagaat ctcagcggca gcctcggtgg tgatctggca gccgcctgcg ccatagacct
     2581 tatatccgtt atacttggaa ggattatggg atgcggtgat cataacaccg gcagaagcct
     2641 tcagataacg gatagcaaag gatacggtag gcacaggcag cagctccggc cacagatgca
     2701 cctgaatacc gtttgcagca aagatgtccg cggcaacctt tgcaaataca tcggacttga
     2761 ttcgggaatc atagcccacg acgacagaag gggtttcata ggtcttattc agatagtctg
     2821 acagtccctg gcttgcctta cctacggtgt gtacgttcat acgattagtg cctgcaccaa
     2881 tggtgccacg cagaccaccg gtaccaaagg acagattttt atagaaggag tcctcaatgt
     2941 ccttctcgga atatgaccgc agttcctcta caatttctgc attggcattt gtaagccaat
     3001 gataataatt tgcattatga tccatagaat ctctccaatc ttttaaaatt ctgctcattt
     3061 atttttaagg ttaggatgaa tatatcagct caaataatat ataaccccac taatgccgcc
     3121 acccaaagta ttataaaata aatctgacaa ttggaatgtc tctatgtgta aaaataactg
     3181 caaaaactct ataagacacg aacataaaaa aacaaatttt ataatctctg ataaattttt
     3241 ccaaaatctt tttctgaagc cttataccac attactagaa ttataaatgg aataaacaga
     3301 ataacatttt caaaacattc tgtagttaat ctaatctccc ctgtcgtttc attcacagag
     3361 taaatccacc aactaccaaa cacattagac aaaggattta gccaaacata tctatccatc
     3421 agtgttctaa aaagaatcat atttgtaaaa aacacaagca aaaacatttt tctaaatgag
     3481 cttgattttc tgaaataccg aatccagaca agaaaagatt ttttcaaacc taatcctgat
     3541 ttctcctcag ccatcgcaaa caagtataaa aacatagcca aaactgcaat taaaatcgaa
     3601 acccaaatat ttgatacaat gcagataaca cattaaccaa aatagaagat atgattttct
     3661 tcataaactc tcctttcatc atgcgctaaa tgagtaccat caagaaggtt tcgtaaaagg
     3721 aggtacccac tctaacatga ataacctcgg ccagcgaaaa taaaactcaa cagaattcct
     3781 atctctatgc tgctataatt tcaacaaatt tacatgtacc agttactaat ctaatataat
     3841 tttttcagca aggtaaattt cacactacac gcatacacaa aaactgtaga aattaaaatt
     3901 attatcattc cacaagtcat ttctattaat gaatttgtaa tccccaattt tgggaaaata
     3961 aaat
//
LOCUS       DAZKPE010000140         3954 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000140 DAZKPE010000000
VERSION     DAZKPE010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.144"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(242..391)
                     /locus_tag="ACG930_002882"
     CDS             complement(242..391)
                     /locus_tag="ACG930_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519988.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            853..1065
                     /locus_tag="ACG930_002883"
     CDS             853..1065
                     /locus_tag="ACG930_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0519989.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1343..3142)
                     /locus_tag="ACG930_002884"
     CDS             complement(1343..3142)
                     /locus_tag="ACG930_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFQ0519990.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3266..3862)
                     /locus_tag="ACG930_002885"
     CDS             complement(3266..3862)
                     /locus_tag="ACG930_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFQ0519991.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1417 a          702 c          681 g         1154 t
ORIGIN      
        1 atattaaata ttatacagat aataacggaa tattatcatc gaaacagcta acaaaattgt
       61 cataaaaaac gagatggttg atattagaac ttgtgttttt gtttaggtct agagataaag
      121 agagacaatt tccaaatata tgtaatgaat acaaaaagac gtttgtcgcg gattaccgtt
      181 acaaacgtct tttattgatt ttccgagatc tcatcagtcg ccatttggaa tggttcactc
      241 cttatctaga ttcgtttaat gctcggactg cttgttcgat tgtaatacca aacgcaacgt
      301 tattttcgtt ttgtgcatca atcgccataa aacggttaga agttgtatca aaagctacgc
      361 ggtattgcat atttgttttt gtaaacgtca taaaattcat ctcctttgta atgtaattta
      421 gttcttgaaa gtttccttta aactttcgaa cttataccaa gtttagcatc gtacgttttt
      481 tgatgcaatt aaaaagcatt tatcattttc cttatttatt ttttcttaaa tggtttagct
      541 attttctttt aatccgataa gtagcccaat catcaaggtt acaaatacta ttgcttgaat
      601 ataaatcata tgctcacctc tttataaata acttagcaat ataaagaaaa aaacgcacga
      661 acaacatagg aatataaaca aacgtttttg tcacaacgtc taagatcgtg ttaaaaaata
      721 gttatctaaa aagcagaaag atactcaaaa taaaaaataa aaaaatggat aaaaacgttt
      781 tcaaatacaa ggtaatttgt tattataaaa taaagaaaaa acaaaataaa aataaagaaa
      841 agagggaatg aaatggtaaa agcagaagta ggaagatctt atatatgcaa accgatcgga
      901 gtatctcatg aactaatcgg ctgtattgaa cgtacatata tcaacacggc tgtcgtgtat
      961 gttgaaagtt atgaccaacg agactatcaa cttatcaatg aaagcaagta tcgcatgctc
     1021 gtaaaattct gtgatattag cgcacctgct gaattggttt cttaaacagt atttttgaga
     1081 attcgcaaga actcccttat aatataaata aagacagaag ggagcgagaa gatatgccaa
     1141 aaagaaaaag ttcagggaaa atgggaatta ttcttgcagt gatctctgca attcctgcta
     1201 ttttagctat tgttcgtgcg atgaaggaat caagagaaag ttaagcacac attatgagcg
     1261 tcaaacaaaa aacgcatata cctgcggtgg caggttatgc gttttttgtt gtataaagac
     1321 ttttttcatt aacgattttt gattagccga ctcccaaaac aaaatttagc agtttatctg
     1381 aataagtgat ttcttcatct gtttgtttca cactttcatt tagtagtccc atctcatcgg
     1441 ttatgatacc atccacacca taaaacatca tgcgactcat agcatctgaa tcgttgattg
     1501 tccatacata tacttctttt ccgtcttggt gggcagaatt aatgaagtta cggttgatcg
     1561 tactatattc cattgtcaga aaatcagcag gcgtcacagg gggcccaaca atattgaaag
     1621 gtaagatgta gcccacataa aagtttggtt ctgcttcttt taaatctgaa acggtttggt
     1681 acgtcaaact ttgcaaaata tgatggttct ctaagataac tttgcggtat ttatggacaa
     1741 atcgttcgac aaggtcatcc gaatcttttt tagaggtctt gatctcaata agtaattttt
     1801 ggtttagctt atgtgctttt tccaaataag aatcaaaaga acaaacaggg gcttgcactc
     1861 cgttttcagt aactgtaaga tttgtcaatt ctttcaatgt aagatcctgt ggtgttccat
     1921 ttacccctgt taagtgacga agatttgcat catgcatcac tacgaaatga ccatcttttg
     1981 tttcctgaac atccatctct acataatcag gatgatagtc tctgcttgtt ttttcaagtg
     2041 cttctaaagt attttgcgcc ccattttggg tactcacacc tctgtgagag acagtcactg
     2101 gttttgtctg aacagctgaa gtcagataat ccatattgta aagacagacg ccaataccga
     2161 aaaaaactgc aaaaagagtc aaaccagtgt ttttcagcgc agagaaacgc aagttggggg
     2221 cttgtgggat aaaccactta gggatctcag gcaagaagcc ttcgtcatcc atgaaatcaa
     2281 caatgatata aaaaatccct acggtagaca tcacgatatt gaataataaa atcccttgta
     2341 aaagcgtcat agcaaacaca gcgctgatca atgcatagtc tgggaaaaat tgttcaacca
     2401 tactttgtgc caaaataaca acgatatatc ctaaagaaga aaggagtaaa atcgtaccgc
     2461 caatcacaat aaattggccc gtgatggcca aaagacgcga tttggtcaat gaccagcttt
     2521 cccgaatggc tgctcgaaaa ggacgatccc gtagaatcat ttccggtaaa gcaaaaatca
     2581 gtcgaatccc aatatagcca aggaaaatat aaacgagtaa aaaggaactg acgatgatcc
     2641 aacgattagc aaaaataaaa tccataatga aagcggggat ttttattttt gacagtagat
     2701 cagaattaaa acttaatccg ctgatcggta gaatcaataa aaaataagca aggaaaaaca
     2761 aaaaagtaat gggtctcact ttcttcagct gaagtatcgt caagtgtaag agttgcttca
     2821 aagagattgg ttctttcttt ttaataaaaa aaacactcat caaaagaaaa gtaaattcga
     2881 aataaactaa cagtaaaatc gtcatcaaaa ctacgattaa cgagagtaga accccaggat
     2941 gttgagaaaa aattgaagga atattgtcat aagacaaata gtcaattgcc cctcggtgta
     3001 aaataaaacg ggtcgtactg ctcaataagg gtaaacaaat aaataaaata aagccatgca
     3061 tcagcaagac atcacggaaa taagcttgtg ttccttttaa aaagtcccaa gcattaccta
     3121 agctacgttt caaataattc atcctatcac ctgctcttca cattatagcg caaatctaat
     3181 gaaaaaggaa agggtgcagt gtgttttgca gaccctttcc cagatttaac attgtcaatc
     3241 aatgactaat tttacaaaat aaatattatc caagaagacc acttagatat tgacctccat
     3301 aaatcaaggc catactatat aagaaaatcg acagtggttt agcaatcaaa atgattagtg
     3361 tatatcgttt cactgacatg tttgtcaatc cagccatcaa acataacgca tcgtcaggag
     3421 caactggaag aaaaatagct agagcaaaca gcttctcaaa acggttttga ttatccagcc
     3481 agccaatata tttgttatat gtcttatcgc taatcatgga aagtatgaat ggctttccat
     3541 aacgacgccc tagcagaaaa atgataatcg aaccaatgca gattccaata tagttataga
     3601 taaatccagc ataagggcca aatatcagga caccagctgc agtactgatc cctccaggaa
     3661 tgattggaat aactacttgc aggatttgga tgaagacaaa aataatcggt cctaaaatga
     3721 tggaatcacc tactaatcct cttaacgcat tcaaatcttt gaaaacacct aaattaataa
     3781 aataaatcgt cagcgcgatt gataggccta atccgataat ggatatgaaa tttatcagtt
     3841 ttcgagaggc agcaatattc attattcatc aactccttag aggttctttg ttaactatac
     3901 tttactagaa aagcaactaa ctgcgccatt ttttgatatg acagaaaaca aaca
//
LOCUS       DAZKPE010000141         3898 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000141 DAZKPE010000000
VERSION     DAZKPE010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.145"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            36..938
                     /gene="gnd"
                     /locus_tag="ACG930_002886"
     CDS             36..938
                     /gene="gnd"
                     /locus_tag="ACG930_002886"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFQ0519992.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            940..1941
                     /locus_tag="ACG930_002887"
     CDS             940..1941
                     /locus_tag="ACG930_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFQ0519993.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            1938..2222
                     /locus_tag="ACG930_002888"
     CDS             1938..2222
                     /locus_tag="ACG930_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFQ0519994.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            2255..3052
                     /locus_tag="ACG930_002889"
     CDS             2255..3052
                     /locus_tag="ACG930_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFQ0519995.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            3066..>3898
                     /locus_tag="ACG930_002890"
     CDS             3066..>3898
                     /locus_tag="ACG930_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFQ0519996.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
BASE COUNT         1245 a          638 c          894 g         1121 t
ORIGIN      
        1 tgtataatga gggtataaga aatggaggcg ctatcatgga aattggtgta attggtttgg
       61 gaaaaatggg attgaattta gctttaaact taaaagagca ccatcacaaa gtacaaggac
      121 tcgacatttc aagtacagct gttagtcagg caagagaaaa tgacattcct gcttatcaag
      181 agatctctga atttctagct acttttgagc agaaaaaaat catctggtta atgcttcctg
      241 ctggagagat aaccgaaaac atgttaagaa aactttttcc aaaactcgga ccaggagaca
      301 ttattattga aggcggaaac tcttattata aagattcaat ccgtcgagca gaagagtttc
      361 agaaaaatga aatcggttac ttggattgtg ggacttctgg aggaatcgaa ggagcacgac
      421 atcaagcctg cttaatgatt ggaggagata aagaaacttt tctatccgtg gaacaattat
      481 tcaaagatgt agcaattgaa agaggatatc tgtatgctgg tgcatccgga agcggacact
      541 tcttgaaaat gatccataat ggaatcgaat atggaatgat gcaagcaatc ggtgaaggat
      601 tccaacttgt acaaaaaagt gagtatgctt ttgacttgga acaagtcgca cgtgtttgga
      661 atcatggttc ggtgattcgc ggctggctga tggaaatcat ggaagatcag ttaaacgaac
      721 atcccaattt aagtaattat cggggaatcg tttctgcatc aggtgaagca aaatggacgg
      781 ttgaaacagc gctagaaatg gctgttccag ttccagtaat tgcaactagt ttgttcatga
      841 ggaatctttc acaggaagaa gatagttttt cagcaaaagt agtttcagca ctaagaaatg
      901 ggtttggcgg acatgaaata gttgaaaagg gtgagtaaaa tgccagatta tcatatagca
      961 atcgttaatt ccagcagttt cggaagagtc tttccacacc acttggaaag attaaagtca
     1021 gttggagacg ttcatttctt tactgttgat caagagattc caggaaaaga actagcggag
     1081 ttacttaaag gattcaatat cattattgca agtgttacgc cattttttcg acgagatttt
     1141 tttgaaaaca aagatgaact gctattgatt tcccgacatg gtattggtta caacaatatt
     1201 gatttaaaag cagcaaaaga acaccagaca atcgtatcta tcatacctgc tttagttgaa
     1261 cgaaatgctg tagcagaaaa taatataact aatttgttgt ccatgcttcg acgcacgaca
     1321 caagcacaag caagagtcaa ggacgatcga tgggaagatc gggcggagtt cgtcggtagg
     1381 acgctgttta acaaaacagt tggtgtgatt ggtgcaggaa ataccggaag cggagtaatc
     1441 gaaattttgc gtaacggttt tcgctgtgat gttctagctt atgatcctta caaatcagat
     1501 ttatacatcg aaagctttgg tgcaaaaaaa gtagaacttc aagaattact ggaacaatca
     1561 gatatcattt gtttatgtgc gaatttgaca gaagagaact atcacatgat ttctgataaa
     1621 gaagtcgatc agatgaaaga aaatgtttat ctatctaata gtgcaagagg cgctctagtt
     1681 gatgaagaag cgatgattaa tggtctgaaa agcggaaaga tcgcaggata tgccacagat
     1741 gttttagaag aagaaccggg acgtcaagat catccgtatt tagcgtttga acaagtagtg
     1801 attacgccac atatatcggc ctacacaagg gaatgtttag aagcaatggg tgaaaaatgt
     1861 gtcagagatg tcgaacagat cagtcagcac cttcttcctg aacgttctgt ccagacaaag
     1921 agcaactata taaaaggatg atgaagaaaa tggtgaacgg tttaaaagtg aaaacaggcc
     1981 ctcaatttta tttatatgaa gaaggtggta tttcaaaagt ttctgatctc ttgaaatcat
     2041 acggcgcgaa aagagtactg gtcacccacg gaacggtatc atgggaaaag gcgctaccta
     2101 aattagtatt tttgaatgac gaaacgattc aattttttta tcatcgttat tctggagaat
     2161 gtagttatgc tgaagccaga cgaatagcta caatcatcaa aaaaatgaaa tcgatttcgt
     2221 agttggcgtt ggcggaggaa aactgaccga tctagtgggt tatagtgcca atcttgcaag
     2281 aatcgatttc ggagtcatcc ctactttagc tagtaattgt gctccatgga cacctcttgc
     2341 tgtcatgtat aaggagaatg gacaagcaga agggaaaaca gaacactttt acagacaagc
     2401 tgcttttttt ataacagatc cccaattagt gattgattcc cctgttccat atttcattgc
     2461 cgggttagca gatacactag caaaatggta tgaatctgag ctcatcttag aacaagattt
     2521 tttgcaagat gaatcatttt tgaagctagc acaagatact gcgaagatct gcaaagaaga
     2581 gattttgaat cattctgcta aagcaatcca agatatggca caaagaaaac tgacatcgga
     2641 gttcaaacag ctttcagaga ttatctttgc tgttgctggt ttagttggag gattaggaga
     2701 taaatacgca agaaatgtgg cagcacatgc tatgcatgac gctatcagta aatatattcc
     2761 ggaaagccat cgttttctac atggagaaaa agtagcgtat gggattttct atcaactggc
     2821 actagaaggt cgctgggaaa aaatagacga gttatatcct ttgtatcggg aattagaact
     2881 gccggtttct ctagaacaaa tgggattatt tccgaaagat aaacagataa tagataaaat
     2941 ggctgaattt attgattcga aagagaaagt gcatttgatt cctatagagg taacacagaa
     3001 atcactgata cagtcaatga tggaactgga aggttatatc agaaagatct gaaggaggag
     3061 gacacatgga aacattaagt gtagtacaaa gtttgttgat tgctttatgg gtagccgcgg
     3121 ttatgtcccg ctggttaggt ggaggagcca cgttgacctt acgtttttct cctttgatga
     3181 ctggattagt cgtcgggttg atcatggggg aagttgcaca agcgatgatt gttacagccg
     3241 ctttgcaaat gatttatatg ggggtttttt ctccaggagg atcaatgcca gctgaaccat
     3301 ctattgcagc agctatcgca gtaccagtcg cattattagg ggatctgtcg ccagaagcag
     3361 cgattgccgt tgcggtgcca gtcggattgc tcggaagtta cttgtatcag tttcgttttt
     3421 tcatcaatac ttttttaggt aaatatacag acaaagctgt agaagatttg aatacaaaag
     3481 ctatggcccg atcaattatt ctttatccaa cggttgcctc atttttatta ttcgttccgc
     3541 ttgttttcat tgctttatat ttaggggcgc cattgatcgc tgatgtaatc aaagctttag
     3601 agggaacagt cgttatccac attcttgaag tagtaggtgg agggttagcg gcaatcggta
     3661 tcgcgacaac tgtatacgtt atcggtcgaa aagattatct ggtctttttc ttccttgctt
     3721 attttatgag tgttgttttg aaatctttag atattacgat ggttacttat gccatttttg
     3781 ggattattat cgctttgatc tttgtccagt cgcaaaaagg gaaacaagta cagcctgcca
     3841 caagcaataa caattcagca tcttttgatg acgaagatga ctatgatgac ggatttta
//
LOCUS       DAZKPE010000142         3723 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000142 DAZKPE010000000
VERSION     DAZKPE010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.146"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            86..1435
                     /locus_tag="ACG930_002891"
     CDS             86..1435
                     /locus_tag="ACG930_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFQ0519997.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="ACG930_002892"
     CDS             complement(1563..2153)
                     /locus_tag="ACG930_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFQ0519998.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="ACG930_002893"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="ACG930_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFQ0519999.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1052 a          692 c          733 g         1246 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 cat
//
LOCUS       DAZKPE010000143         3621 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000143 DAZKPE010000000
VERSION     DAZKPE010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.147"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(28..1026)
                     /locus_tag="ACG930_002894"
     CDS             complement(28..1026)
                     /locus_tag="ACG930_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFQ0520000.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1101..1397)
                     /locus_tag="ACG930_002895"
     CDS             complement(1101..1397)
                     /locus_tag="ACG930_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520001.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1390..1683)
                     /locus_tag="ACG930_002896"
     CDS             complement(1390..1683)
                     /locus_tag="ACG930_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFQ0520002.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1829..2380)
                     /locus_tag="ACG930_002897"
     CDS             complement(1829..2380)
                     /locus_tag="ACG930_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFQ0520003.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2554..2853)
                     /locus_tag="ACG930_002898"
     CDS             complement(2554..2853)
                     /locus_tag="ACG930_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HFQ0520004.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2880..3155)
                     /locus_tag="ACG930_002899"
                     /pseudo
     CDS             complement(2880..3155)
                     /locus_tag="ACG930_002899"
                     /inference="COORDINATES: protein motif:HMM:NF017894.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
     gene            3493..>3621
                     /locus_tag="ACG930_002900"
     CDS             3493..>3621
                     /locus_tag="ACG930_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HFQ0520005.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGI"
BASE COUNT         1063 a          712 c          505 g         1341 t
ORIGIN      
        1 tttttctttg ataaataata ttttcaatta tttaatcatt tgaaaattgt tagtcattcc
       61 aatacgttga gaaattcttc catctgtata aacacgaaat tgttttccac cagccatggt
      121 cgtgtttcca tcatcatccg ttacaatatt aattgaatag tagcttccat tttcatcttg
      181 cattagatct ttcatatatt catttgtgct aattaaatta gtatttgata catttttatc
      241 aggagaatca tacaaccata aagctttatt atttagcaca gattctttag cagcttccca
      301 acttgaaatt cctgaactac ttgtagattg tgtcgttgta gttgttgctt gttgagtaga
      361 ttcttctact actggtgttt gaggagtttg tccattcaca atatcactga aaccttgttt
      421 taactgttga ttttgagttt cgttaaagta cagataatta ttttcattac cttgattttg
      481 ttgcgttaaa taaactttag gttgtccatt ttgaaaaccg aaaaagtaaa catgctgccc
      541 taaatattct ccagtttcta catcagaata aactgctact aaattgaaat ctgcatgacc
      601 agttccatct tctgaccatt gtacggtaac tggtgcttca ttgattgcca ttttccaatc
      661 gccattaatc acggcttgtg gtaaaggagt gccatacaga cttacattat tctgaagatt
      721 gtagctttta tattcttgac ctaatgtctt tccccattgt gtgacaaaag tttctaattt
      781 ggaagcttta ttcgtatccc acaaagtatt cttaacctct tcagaagaag attcagtgat
      841 tgaacttgca cttgtttcca cagattgctt catttctgtt gtagtttgtt cagttgattg
      901 cgttttactt tttttagtct caattgttgt atcagtttct atagtcgctt tagtcctcgt
      961 attctcagat gtacaaccag tgaataaaat tcccattcct attagtaata acagccattt
     1021 tttcattata tttccccctt tcaatttctc cctcacgtac ttattctatc agacaattaa
     1081 ttgatctaaa tggtaatctt ttaatcgatt ctttcccaat aatgtcgata gcccgtatgg
     1141 cagcggtctc ttccttgagg actctcagat ggattaaaac tagtagaaat ttcccttcca
     1201 catcctctac agcgataagt tctcattatt tttgggctat tagtattatt tttcttagtt
     1261 agagctatga gtccaactat gattacccca actgtcttaa ttacttttcc tttatctata
     1321 ttcggatgcg caagcatata ttgatataac caatatccac cgtaaattaa accacctaat
     1381 acaatcagct tagccatgta ctcgtctcct ttctttttgt ttaattactt tttgaatcca
     1441 tcttgcagag aaaccataaa cttctgtcaa ttgacggata tctacagttt tttcctgttc
     1501 tatcatgttt tcgattcttt ttctaactaa ctcacgatcg tacattttca ttggaaaaga
     1561 aatctgttgc cctcgaaaag caagataaaa ttgatagagc aattctgaat ccagttccat
     1621 ttcctcaaaa aagtcattca tacttttata agagttactc aaacaagttt catcaatctc
     1681 catctacaca ccccctgtta ttttttacat aatgaaaata gcatattact gggtacattg
     1741 ataattcata taacatgtat catcacatgt atttttaaag tcaaaaagca tgtaaaacta
     1801 cttataagta acatgagaaa ataaaatgtt atttttcttg aaataataat tgactatctg
     1861 ccaattgcca ttcattacga acatgaatac ttagtgggtg ggataactta ccttctgcat
     1921 ttatcaatac tttggtcatc ttcttttgtt tcgcactcaa ttgatcgtaa atagtctttg
     1981 cttgttcata agccacttga ctcgtcgctg taatcgaacc acaagcaaaa ataatggtat
     2041 tgattttctt ttctgtaaaa acagtcgtta atatttccaa agattgttca tcatttcctc
     2101 gaagaaatac ccgaggactt ttcgcttttg tgtacgaaaa aagattcaca gcaataaaac
     2161 cagtaaatcc taattgtcgg atattctttt cgattaataa catactcaaa tcattcgtaa
     2221 atggttctgt atctgttgga cgaatagtaa tgactactgc taatttatct tccgcttctt
     2281 ttcctttgat cgcccattgt cgtttgaaaa catagcgatg ggtatgatga ggatctcgcc
     2341 aaacttctgt ttgtgtggtc actaattctt tttcaatcat ctctttttct cctatgctat
     2401 tttttgttca agcacttcaa ttaccattgc cgttataagt gtcaatacta gttgaaaata
     2461 tttcatattc tttctccttt tttcttcaga atttgatgaa tcgcggtaag gatatcttct
     2521 aaacatttcg caatcattct caaataatcg atcttattca tccgttcctc caatctgact
     2581 ccaaaccaat cgtccttcta ccagtaaccc acgaacaaat tctcgctggc tggtaatatc
     2641 tgtaatgaaa taaactacat agtcttttcc atcttctggt gcgcaataaa tataaagatg
     2701 tgtcatcact aaacgtggta gatgaacatc ttcaggaagc atacccattt caatttcctc
     2761 tttttccatc gtaacggatt catagcccca ctcttcagaa gcagtgacca gctgtgcaca
     2821 cttttccagt acttcgatag ccgtttctaa caagtccttt cgttcctttc ttttagatac
     2881 tagtattctt ctggtaataa catcgtttga tactcacccg aatcaatggc ccatattttt
     2941 tgagacactg atttcaaacg aagcttaggt gaaatcagat actcttttct ttcttccggt
     3001 tcttcttgac gatgaaccaa cttttgattt cctttttccg tagaaaattc aaaaatttga
     3061 agatagtcta aaggaaattg cttttgaacg ttttgatcga ttagattcca acataaagct
     3121 tgtaattcca ccggcaaact gtccattact ccctttgtga cataacgtta tcctttattt
     3181 tgaaacattt cttttccctc ctttgccata aaaatagccc aatcttctat taaagaagat
     3241 tgggcttcat ggatataata tatatttgta aataaagtta attcagttat aattatcaaa
     3301 actacacaat tattaaagtt tttcatatct ctttgtttag taagtttttc taaatcttaa
     3361 cccgtggtgc tagttaattt tttcctagag gaaaatgtct aaacatgttg gtaaatcaac
     3421 aaaaaaacgc atatagtagt ctcaaaactc ccaagaaatg aggactattt aacaaactac
     3481 gatggttacg tcgtgacaac tgaacatttt gacttagcca atcctgttac taaagtcgat
     3541 gatatccccg attatgaaat gtacagtcaa acaatcgata gcttaaataa gcgttttggc
     3601 aatcgtgttt taaaaggcat c
//
LOCUS       DAZKPE010000144         3553 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000144 DAZKPE010000000
VERSION     DAZKPE010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.148"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2232)
                     /locus_tag="ACG930_002901"
     CDS             complement(<1..2232)
                     /locus_tag="ACG930_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFQ0520006.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="ACG930_002902"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="ACG930_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         1010 a          782 c          551 g         1210 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac gacgaaaaat aaatcactac cagtcaactt ctataatatt
     3481 accaaataac aaactaacta tccatcaata acgtgtttta ttttttaaaa tttctataaa
     3541 aaaacaatca ttc
//
LOCUS       DAZKPE010000145         3533 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000145 DAZKPE010000000
VERSION     DAZKPE010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.149"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            368..415
                     /locus_tag="ACG930_002903"
                     /pseudo
     CDS             368..415
                     /locus_tag="ACG930_002903"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            431..2350
                     /gene="tet(M)"
                     /locus_tag="ACG930_002904"
     CDS             431..2350
                     /gene="tet(M)"
                     /locus_tag="ACG930_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFQ0520007.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2469..2636
                     /locus_tag="ACG930_002905"
     CDS             2469..2636
                     /locus_tag="ACG930_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFQ0520008.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2696..3049)
                     /locus_tag="ACG930_002906"
     CDS             complement(2696..3049)
                     /locus_tag="ACG930_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520009.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT         1200 a          539 c          673 g         1121 t
ORIGIN      
        1 caatttgatt tggtacttga aaagaacggg agtaattgga agattataga ataacaaata
       61 ttggtacatt attacagcta ttttgtaatc acgtactctc tttgataaaa aattggagat
      121 tcctttacaa atatgctctt acgtgctatt atttaagtat ctatttaaaa ggagttaata
      181 aatatgcggc aaggtattct taaataaact gtcaatttga tagtgggaac aaataattgg
      241 atgtcctttt ttaggagggc ttagtttttt gtacccagtt taagaatacc tttatcatgt
      301 gattctaaag tatccggaga atatctgtat gctttgtatg cctatggtta tgcataaaaa
      361 tcccagtgat aaaagtattt atcactggga tttttatgcc cttttgggtt tttgaatgga
      421 ggaaaatcac atgaaaatta ttaatattgg agttttagct catgttgatg caggaaaaac
      481 taccttaaca gaaagcttat tatataacag tggagcgatt acagaattag gaagcgtgga
      541 caaaggtaca acgaggacgg ataatacgct tttagaacgt cagagaggaa ttacaattca
      601 gacaggaata acctcttttc agtgggaaaa tacgaaggtg aacatcatag acacgccagg
      661 acatatggat ttcttagcag aagtatatcg ttcattatca gttttagatg gggcaattct
      721 actgatttct gcaaaagatg gcgtacaagc acaaactcgt atattatttc atgcacttag
      781 gaaaatgggg attcccacaa tcttttttat caataagatt gaccaaaatg gaattgattt
      841 atcaacggtt tatcaggata ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa
      901 ggtagaactg tatcctaata tgtgtgtgac gaactttacc gaatctgaac aatgggatac
      961 ggtaatagag ggaaacgatg accttttaga gaaatatatg tccggtaaat cattagaagc
     1021 attggaactc gaacaagagg aaagcataag atttcagaat tgttctctgt tccctcttta
     1081 tcatggaagt gcaaaaagta atatagggat tgataacctt atagaagtta ttactaataa
     1141 attttattca tcaacacatc gaggtccgtc tgaactttgc ggaaatgttt tcaaaattga
     1201 atatacaaaa aaaagacaac gtcttgcata tatacgcctt tatagtggag tactacattt
     1261 acgagattcg gttagagtat cagaaaaaga aaaaataaaa gttacagaaa tgtatacttc
     1321 aataaatggt gaattatgta agattgatag agcttattct ggagaaattg ttattttgca
     1381 aaatgagttt ttgaagttaa atagtgttct tggagataca aaactattgc cacagagaaa
     1441 aaagattgaa aatccgcacc ctctactaca aacaactgtt gaaccgagta aacctgaaca
     1501 gagagaaatg ttgcttgatg cccttttgga aatctcagat agtgatccgc ttctacgata
     1561 ttacgtggat tctacgacac atgaaattat actttctttc ttagggaaag tacaaatgga
     1621 agtgattagt gcactgttgc aagaaaagta tcatgtggag atagaactaa aagagcctac
     1681 agtcatttat atggagagac cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc
     1741 gccaaatcct ttctgggctt ccattggttt atctgtatca ccgcttccgt tgggaagtgg
     1801 aatgcagtat gagagctcgg tttctcttgg atacttaaat caatcgtttc aaaatgcagt
     1861 tatggagggg atacgctatg gctgtgaaca aggattgtat ggttggaatg tgacggactg
     1921 taaaatctgt tttaagtatg gcttatacta tagccctgtt agtaccccag cagattttcg
     1981 gatgcttgct cctattgtat tggaacaagt cttaaaaaaa gctggaacag aattgttaga
     2041 gccatatctt agttttaaaa tttatgcgcc acaggaatat ctttcacgag catacaacga
     2101 tgctcctaaa tattgtgcga acatcgtaga cactcaattg aaaaataatg aggtcattct
     2161 tagtggagaa atccctgctc ggtgtattca agaatatcgt agtgatttaa ctttctttac
     2221 aaatggacgt agtgtttgtt taacagagtt aaaagggtac catgttacta ccggtgaacc
     2281 tgtttgccag ccccgtcgtc caaatagtcg gatagataaa gtacgatata tgttcaataa
     2341 aataacttag tgtattttat gttgttatat aaatatggtt tcttgttaaa taagatgaaa
     2401 tattttttaa taaagatttg aattaaagtg taaaggagga gatagttatt ataaactaca
     2461 agtggatatt gtgtcctgta tgtggaaata aaacacgatt aaagataagg gaagatactg
     2521 aattaaaaaa attccccctc tattgtccga aatgcagaca agaaaattta attgaaataa
     2581 agcagttcaa agtaactgtg attacagagc cagacgcaaa gacgcagagc cgataaaatg
     2641 agattaatac aatctcattt tatcggctct ttccgttatg tatggattct tttaattagt
     2701 cttcgatgtt tcttgcttcg ttgataccgc tggctaaaga ttccattaag gatagttctt
     2761 tgtctgtaaa gctatccatg tatttctcta tctgtaatcg tcgggtgctt tttaccaagt
     2821 tattagcagg taagaaaaat tcatcaacgg aaacatgaag taacgataca aggtcataaa
     2881 gaacttgtat gctggggtgt tgccctttat tttcaatatt agttaagtac cgtgggtcaa
     2941 tttcaatcaa tgctcccact tgttcacgag ttaaacctcg tttcaatcga gcttctttaa
     3001 tggctaaacc aaaggctcta aaatcatatt tatcttcttt tttacgcata gtagaccacc
     3061 tctatacatt ttattgttcc tactgaatta aaaacaggta tagaaaaacg tgttatatgg
     3121 tttataggtt tatatttaat aaaaagcact actaaacgcc aataaaaaaa accgttatat
     3181 ggtagtgcta tttacgctgt taaaatattg tatattactt ccaaatggcg gtttgttgga
     3241 ggtcaacgtc gccatgaagt acatcatata caataaattt ccttacattg ggttcttgtc
     3301 aaaaaaagtc gtctatctgc aatagataag tacgtccacc aatgtggttt tataaatcat
     3361 atagatagaa taacagaagc atgtaaacag agaaataaat ctgtttatat gcttttttgg
     3421 ctattcagaa cttttttaca aagtttattt atcagtaatg caacaaatcc ccctttcaca
     3481 ttgggactaa gagtgaaagg agataaacga gcaaggctca cttcctttcc tag
//
LOCUS       DAZKPE010000146         3415 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000146 DAZKPE010000000
VERSION     DAZKPE010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.150"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..813
                     /locus_tag="ACG930_002907"
     CDS             <1..813
                     /locus_tag="ACG930_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0520010.1"
                     /translation="YIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNTKV
                     GDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYSTIR
                     LLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQAQV
                     ASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQTA
                     IEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1043..1273
                     /locus_tag="ACG930_002908"
     CDS             1043..1273
                     /locus_tag="ACG930_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFQ0520011.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(1496..1594)
                     /locus_tag="ACG930_002909"
                     /pseudo
     CDS             complement(1496..1594)
                     /locus_tag="ACG930_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1859..2314)
                     /gene="tnpA"
                     /locus_tag="ACG930_002910"
     CDS             complement(1859..2314)
                     /gene="tnpA"
                     /locus_tag="ACG930_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFQ0520012.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2557..3415
                     /locus_tag="ACG930_002911"
                     /pseudo
     CDS             2557..3415
                     /locus_tag="ACG930_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
BASE COUNT         1133 a          586 c          591 g         1105 t
ORIGIN      
        1 tatatctatt taattaaaga aaattatcca tttttaacga agtctgaaaa aaaagtcgct
       61 gattttattt taaattctgg gaaaactatt atttatagta cgatgagtga tattaagaaa
      121 aacacaaaag ttggcgatgc tactattatt cgcttttgtc aaaaaattgg tttttctggt
      181 ttttctgatt taaaaattga aattgcaaag gaagacttta gtcaaaaaaa agaacatccg
      241 actagtgtaa agtactatga tgaaattgct aatagtttaa cagaagctct ctattccact
      301 attaggcttt tagacgaaga aaaattgaat gaagccatta aaatgatcac tcaatcaaaa
      361 aacatatata tatttggagt gggatctagt ggaaatacta gtcttgattt agaaaatatg
      421 tttcttcgcg taggagttca agcaaaagct gtactagacc ctcattttca agcccaagtc
      481 gcttctttat taacagttaa tgatttagta atcatttttt ctttatctgg gaaaacgaaa
      541 gatacttatg attcattgaa aatagctaaa aaaaatggcg caaaaattat tgctataact
      601 aactatattc attcacctat aggaaagtct gcagacttag ttttacaaac agccattgaa
      661 gaatttctta atggtggatc tttagctgga aaaatatcac aactttatat ttgtgatcta
      721 ttagttcatg gttatgaaca aaacaataat attgattcag ttgaattaag agaaaaagtt
      781 ttgcgctcta ttattgataa aagtattgag tgaactaccc ccacttagct aaacctaacg
      841 gtttttaacg attgaagtag gcaattcttg ggatgagagc atacttgata gcttattttt
      901 tactaatagc ggtggctctt attgaccaaa tatccctgta gttcctacgg ttcttgattt
      961 tatctaaaga tatttttatc gtggaagcta ttgatcaact tgaaagaaaa acgtgtagct
     1021 cattatcact agtttatcga gtatggatga agcaatggat catcctctct taaataaatt
     1081 tattaaggat ctgatccttc aaattttttc catgatcgat gagcaggaac ctactgaatc
     1141 taaacgacat cgggcacaag gaattattaa gattgctaag cgaatgtttt ctataaaggg
     1201 tgttctaagc tatacagtgt taattcaaaa gattcccaat catcttgttt ataagaacaa
     1261 cgttgaagat taaaaaagtg tttcaatgct aaaattgcaa aatacttcaa tgttatgaga
     1321 caaactgtct ataagaatca atttccaccc atttcatcac ttgttaaaag tttatgatcc
     1381 ttttgatttt tatattaatt tatctgtatt taatacagat tttatttatt agttcatctg
     1441 cctattgtat tttattttgt tgccttacca tctgaagtaa atatactctt aattgtcaaa
     1501 ttaagttaga cagatcatca atacttacgt aactcaaaaa tacttccaaa ggtgttcgat
     1561 aatccagtga ttttctagga agattatttc tgcgccagca ttttctaatg tttgaatttg
     1621 tgttttgtaa tcttggttgc ttgtgctaat tcttgaatag ccgtaaattg ccaaaatttc
     1681 atcacccttt ctggacataa gtttctgaca ccagttaaaa tcaagtctat cagtaaccca
     1741 tacacccgtg aggacgggtg tatttttaat ccccctagaa ggggtcgaca ctcgctgccc
     1801 cttaaaaggg gatttttaaa agaccgccaa ctgctcatct tcactcactt acttctcttt
     1861 attttttaaa tggttctacg tactctcttt tacttataat atatcgaatg cgatcatcag
     1921 cttcttgttc acggatgtat ttttcatttg tcttttgatt caatccgact gtactcacat
     1981 agtatctctt cgaccaaaag gatttgtttc cgtatttata tttgagattt gcgtgctgct
     2041 cgtggattag taccgcacta cgacctttca gataccccat aaaactggat atacatattt
     2101 ttggtggtac tcgaacaagc atgtgaatat gatctagcat tgcatgtgct tctatgattt
     2161 ccacatcttt catttcgcac aacttcctaa gtatttttcc aagatctttt cgtaattgcc
     2221 catagattac ttttcgttga tattttggtg taaaaataat atgatactta caattccaac
     2281 gagtatatgc taaactttta tcgtcatttg acatgaaaaa actcctttcg atctgatgag
     2341 cggttggtag ccactcacta gtatatcgaa aggagttttt atcgctaaag atacttcttc
     2401 cacgcgtaga aacgcgcggt tttcttgttt cgcacgcttt acgcacaaaa ctgactgaag
     2461 tcattaagaa aataaaaggg tctaaaactt ttaagttttg taccgacccc caaaagttag
     2521 accaaaaaat ctaacttttg gaggtcggta ttttttatgg ctaagtatac ttttgaactt
     2581 aaattaaaga tcgttcatga ttacttggat ggtaaaggcg gaagtgatta tctggcaaag
     2641 aaatattcca ttaaggctcc atcacaagtg aagcgctgga tcaatgccta tcaagaattt
     2701 ggtgaagagg gtctagtaag aaagcgacaa aagaaaaaat attctgttca atttaagctg
     2761 gatgcgatag agttatatct aacaagtgag ctgtcctatc gtgaagttgc caacacactt
     2821 aacatgaaca accctaattt gatcgctagt tggatgcgtc aattccgtga gggtgggatc
     2881 gatggactct caaaaacgaa aggatgtcca cctatcttgt ctaagaaaaa tgaacccaaa
     2941 aataagaaaa aatctacaac taaagcaacg tctaaagaac gtgaacgcat cgaggagttg
     3001 gagaaacgag tccgttccct tcaaattgaa aatgcctttt taaaagaatt gaggaagctg
     3061 cgaaaacagg aagcccaaca acgacgaatg aagcaatcgc acgaatcatc gcaagcctcc
     3121 gaggaccgtt taaattagtt gagcttctag aaactttaaa gttccctaag gcaatcttta
     3181 tgtactggca aaaacgattg gaccgtaaaa atccagatca agagattgaa gcggaaatgc
     3241 ttaaagttcg ggagaagcac aaggattatg gctgtttacg gatgaccaat gaactaagaa
     3301 accgcggttt ctctatcaat aaaaagaaag ttcagcgcct gatcaagaag ctaggaataa
     3361 aagtaacgac atacacacgt aaatcacggc gctacaattc ttatcgagga caagt
//
LOCUS       DAZKPE010000147         3313 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000147 DAZKPE010000000
VERSION     DAZKPE010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.151"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(25..1572)
                     /locus_tag="ACG930_002912"
     CDS             complement(25..1572)
                     /locus_tag="ACG930_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFQ0520013.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1674..2027)
                     /gene="tnpB"
                     /locus_tag="ACG930_002913"
     CDS             complement(1674..2027)
                     /gene="tnpB"
                     /locus_tag="ACG930_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFQ0520014.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2017..2211)
                     /locus_tag="ACG930_002914"
     CDS             complement(2017..2211)
                     /locus_tag="ACG930_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520015.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            2446..2616
                     /locus_tag="ACG930_002915"
     CDS             2446..2616
                     /locus_tag="ACG930_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520016.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            2630..3247
                     /locus_tag="ACG930_002916"
     CDS             2630..3247
                     /locus_tag="ACG930_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0520017.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNAIQQKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKSKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRKRYNVTVDQRKNKGKRDS"
BASE COUNT         1015 a          607 c          631 g         1060 t
ORIGIN      
        1 tagaatcggg aatgtttggc gtttttagtt acgagaaaaa tgttgttgta catccttgtt
       61 ccaaggcaac agttgatcta aagtttctgc tgaaagtacg ggaagatttg gtatcttatc
      121 aaatagaaac tctagatact ttacaggatt caatccgtta agttctgctg ttttatatac
      181 actcagaatg attcctgaag ttcgtgctcc ttcaagactt gtggaatgca accaattttt
      241 ccgtcctatc accagctctt tgatatttcg ctccgcacga ttatttgtga gttctaaacg
      301 accatcttca aaaataggtt caaaaccact tcgtagttta cacgcatatt gaacggctgc
      361 atccaacttg gattttgcaa caggatctat cgttgccatc cactcataaa aagcaataaa
      421 taatggacgc agttcttgtt gccgacagct taatcgcttc tcaggagaaa agtctttcca
      481 tttcttttct aggacaaacc atttatccaa ttgtttgact gcttgagctg cgggaatatc
      541 cgtgtttttc tttccttttg gaattgcttc gaaaaatttc cgccgaacat gcgcgaaaca
      601 atagacaagt cgtacacttt ccacggcatt atacccgcta tagccgtcac agtgtaaata
      661 ccctgtaaac tccttgagaa aagttttcgg aacatctcca gcacgacttt cgtcgtggtg
      721 ataataaacg atgggatgct gactgtcttt tcctgtacaa aactgccagt aataggtatc
      781 tgttttggca ctttcaatca cacgataact tgtttcatcc ccgtgtagaa tctcttcttg
      841 attaagatag actcttaatc gttctcctaa agggtctaac gcgttttgca ctgctttaat
      901 atgccaattg gtgatattat ctctcgaaat atccaaccca tgtgtttgtt tccaatagtt
      961 ctcttgccga taggcaggaa ctttctgacc aaatttcatc cggatcgttt ccgccactaa
     1021 actattggaa cctaagctat tagaaatcaa aggtttagga acgatcgctt ttttaaaaga
     1081 agaaagtcct tctttttcgc agcttttaca acaataggta tgttgataat gggtgagaca
     1141 atccaacata gcctgatgga aacgaatttc ttctcgtact tttgtccgtc cgatatcttt
     1201 catctgtgaa ccgcaatgtt cacaaaattg ttcttccaaa ggaaggagat gttctttctc
     1261 tgttataggt aagtgtttga ttttgtctgc tttcgttcct acaactcgtt gatgtccttt
     1321 tactggaata atggtggcag ctgcttctgg aacacttaca gaaatttctt catcactaaa
     1381 aagattcaat tgcccattcg tttcctcaaa gagagtctct ttagagcgtc caaataattt
     1441 gttggttaaa taattgacct tttcattcaa tagttggatt tcagttgtaa gattctgaat
     1501 ggtttgttgt tgtgcttgat tggttttatg ggcttcttga agcaactgaa gcaacgtatc
     1561 tgtagtttcc aaaatttttc accaccttga atcgaactga ttttgttaca gaataccaca
     1621 agaaacgcac aagaaatagg ggttcaacac attttttgtg ttaacccccc agcttaaaaa
     1681 actccttttt ttcctggcaa aatagctcga ggttgatcga tacttaatcc ttctaacaac
     1741 catcgaacct gttggttcgt taaggttcga acttcgtctt tcgtccgagg ccattttaac
     1801 ttgccgtttt ctatccgctt ataacagaga agaaaaccat caccgtccca atagagaagt
     1861 ttgaaacggt cttgacggtt cccgcaaaat aaaaaaacgg catcttcgta aagctcgagt
     1921 tgatactctt gttgaataag actggcaaga ccatcaattc cttttcgcaa atctgttttt
     1981 ccgcacacaa tataaatatg tttggtttga agtaaatcat aaagcattgg acaacagttc
     2041 tttcaaaata gcttgaagaa tataattgtt aataccgtta tagatcaaaa cttcagaacc
     2101 attctctctt ttgatgcgca tcgctaactt ggcagccgcg ggtttacctt tttctggtgc
     2161 actcttttcg tttcctaatt ggacaggaac aatctcattt aatttataca tagaaaacct
     2221 ccagacttct tgatagctca agtatatctt gaggtgcatt tgttagtaag gtactgttct
     2281 atggggcgct tacttcacaa ctcttatagt ggctcagtta attaggtcag aaagttactt
     2341 tctcttgagg acaacagagt atacttattt gtcctaatat gattttagca gtataattga
     2401 cttggtgaat aggtcattta agttgagcat aataggagga gtaaaatgaa aaaatttatt
     2461 tatcgagttt tagaaaatga cgaagtggtg gctattttta atgaacaaca atatgcgcaa
     2521 gattttatcg cttacgaaaa gacaatttct gataagcaat ttgaaattga aaaagtagat
     2581 atagctgatt ggttattgca accgagagaa ttttagaggt tggttgaaaa tggctaaaat
     2641 tggttatgca cgtgtcagta gcaaagaaca gaacttagat cggcaattac aagcgttaca
     2701 gggcgtttct aaggtctttt cagacaaatt aagcggtcaa tcggtcgaac gtccacaatt
     2761 acaagctatg cttaactata ttcgtgaagg ggatattgtt gtagttactg aattagatcg
     2821 attaggacgg aataataaag aattaacaga attgatgaat gccattcaac aaaaaggagc
     2881 aacgcttgaa gttttgaatt tgccctctat gaatgggatt gaagatgaaa atttaaggcg
     2941 tttgattaat aatttagtga ttgaattata taagtatcaa gcggaatcag aacgcaaacg
     3001 tattaaagaa cgacaagccc aagggattga aatagctaag tcaaaaggaa aattcaaagg
     3061 tcgtcagcat aaatttaaag aaaatgatcc acgtttaaaa catgcttttg atttattttt
     3121 gaacggttgt tccgataaag aagttgagga acaaactgga attaatcgca gaacgtttag
     3181 aaggtatcgt aaaagatata acgtgacagt cgatcaaaga aaaaacaagg gaaagaggga
     3241 tagttaatga gtacagttat tttagctgaa aaaccaagcc aggcgttagc ctatgcccag
     3301 gcatttaatc aga
//
LOCUS       DAZKPE010000148         3230 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000148 DAZKPE010000000
VERSION     DAZKPE010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.153"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            169..858
                     /locus_tag="ACG930_002917"
     CDS             169..858
                     /locus_tag="ACG930_002917"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0520018.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            872..2374
                     /locus_tag="ACG930_002918"
     CDS             872..2374
                     /locus_tag="ACG930_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0520019.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            2387..2863
                     /locus_tag="ACG930_002919"
     CDS             2387..2863
                     /locus_tag="ACG930_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0520020.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(2960..3070)
                     /locus_tag="ACG930_002920"
                     /pseudo
     CDS             complement(2960..3070)
                     /locus_tag="ACG930_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1068 a          441 c          618 g         1103 t
ORIGIN      
        1 taactcatac aaactcctct acaatttcaa cttttctcca ttatactcca aaataataaa
       61 aaaaactcct aaatactcca tttttatctt tacttttatg aaagcggatg ctatattgtt
      121 tttggagttg ttatccaaaa ataataaaaa attggagtgt ttaggataat ggataaaaag
      181 aggtttttag atcttatttc aaaaggtttg attgtttcct gtcaagcatt acctggtgaa
      241 ccattttaca aagaggaaga aagtttaatg ccttattttg ctttggctgc tcaaagggct
      301 ggagcagttg gtatacgtgc aaattctgtt cgagatatta ttgaaattag aaagtgtgta
      361 tcattaccaa tgattggaat tattaaaaga gattatccac cagaatctcc attcattact
      421 gccactatga gagaagtaga tgaattagta gaaaccggtg ttgaggtaat cgctcttgat
      481 tgcactctta gaaatcgaca tgatggacta tctataaatt cttttattac taaaataaaa
      541 gaaaaatatc ctcatcagtt atttatggca gatatttcta catttgaaga aggcaaaaat
      601 gcatataaag caggaataga ttttgtagga actactttaa gtggatatac tgaggaaagt
      661 aaaaaacaag atgggccaga tatagatttg attaaaaaat tggtagaaga agggatttgt
      721 gtaattgctg agggaaggat tcatactcca gaacaagcaa aagagataaa aaaaatagga
      781 gttgcaggta ttgttgtggg tggtgctatt actcgaccac aggaaattgc atcaagattt
      841 gttaaagcat taagttaggg ggagaaataa aatgtttaaa aaattttcac aattaggacg
      901 cgctttcatg ttaccaattg ctatattacc agtagccgga ttactattgg gactgggagg
      961 agcgttaaca aatgagagtg ctataaatgc ttatccattt ttagatcaac cgtggttgca
     1021 tacaatttta agtattatga gttatgctgg aaatgcagtt tttgcaaacc tagcactaat
     1081 ttttgcaatt ggtattgctg taggacttgc aaatggagat aaaggaacag ctggtttagc
     1141 tggtggagta gcttatctag tatatactgc aactattagt gggtttcttg aacttttttc
     1201 agcaaaagat gcaacactag atacaggtgt agtgggatca attgttgttg gtggtactgt
     1261 tgcattttta cacaatcgtt atagaaaaat tgaattacca caattcttag gtttttttgg
     1321 aggatcaaga tttattccga ttgtttctag tttagctgca atcattattg gttctttctt
     1381 ttatttaatt tggccaccaa ttcaaaatgg tttagtagtt gctggtgaac aaattgccca
     1441 aatgggtagt ttaggaactt ttttatatgg ttttttattg cgtttaacag gtgctgttgg
     1501 actacaccac accatttacc ctttgttctg gtatacatct ttaggtggta ccgaaactgt
     1561 agctggatca acaattgctg gagcccaaaa tattttcttt gcccaactag ctgatccaaa
     1621 ccacactggt ctgtttactt atggtactag attttttgca ggaagatttg caacaatgat
     1681 gtttggatta ccagcagcat gttatgcaat gtatcgtgca attcctaaga aaaatcgtaa
     1741 aaagaatggt gggctttatt ttagcggggc ccttacatca tttttaactg gaattactga
     1801 accagttgaa tatatgtttt tatttgttgc tccttggctt tatgtgattc atgcattctt
     1861 agatggatta tctttttatt ttgctgatat cttaaatatt cgtgtaggga attccttttc
     1921 aggtggtttg atcgactttt tattattcgg tgtacttcaa gggaatgaca aaactaattg
     1981 gttaaaatta attccttttg gtattgcatg ggcatttata tatttctttg tttttacatt
     2041 ctttatcaaa aaatttaagg tagctattcc tggaatggaa gaagaatcag aagttcattc
     2101 tgaaaaagta ataaacaaaa atacatcatt acatgaagag tctcttatca ttattgaagc
     2161 tcttggtgga aaagaaaata ttgagtctgt tgaagcttgt gcaactcgtt tgcgtgttgc
     2221 tgttacgaat ggggagatta ttcaaaaaca aacaataaaa gacactggtg caactgctgt
     2281 cttcgaagtg aagggtggca tccaagctgt ttttggaggg aaagctgact tattaagtca
     2341 agaaatcaat caaatattag gaaaagataa ttaggaggtt tttaatatgt ttgaaatttt
     2401 caaaaagaaa aaacaagaaa ctttttatgc accttgttcc ggaaaaatca tttccatcac
     2461 agaagtaaat gatcctgtct tttcacaaaa attactaggt gatggttttg ccgtcatacc
     2521 tgatggttca aaaatttatg ctccattggc tggtcgagta acaaatatat ttcctactaa
     2581 acatgctatt aatataaaaa gcaactcagg cattgattat ttgattcata ttggaattga
     2641 tacagttgaa ttacaaggag agcctttttc gatttgtgtt caagaaaatg atgaggttac
     2701 tcctgaaacc tcgttggttg atgtggattt tgacaaaata ataaaatctg gtaaagatac
     2761 ttctgttata gttgtttttc cggagaaaaa tcagttcaat gatttaataa tagataatgg
     2821 tcgaattgct catgggaatt catgtggaaa aatcactttt taaaaaagtg tatataaaaa
     2881 gctataaaat aagctaaata ggatatttgt caaatgaagt tggtgaacag aaagaactgt
     2941 tttctttctg ttcatttttt tattttatta gtaatgattc cccatgccaa atcatgatcc
     3001 gtaatttaaa gttataaaag cttcgaaatc cattggcatt tcgttggaat accttgatat
     3061 gattattcaa atataaaata tagagagaag agagagaggg aagatattta taaagggcaa
     3121 agttatgttt actcaactta ggaaatagaa atagatcaat ttatattctc ttgtcaatcg
     3181 aatatgaacc ttagcactat ataccaaata tagtaaaatg ctgaaagatg
//
LOCUS       DAZKPE010000149         3199 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000149 DAZKPE010000000
VERSION     DAZKPE010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.154"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            301..585
                     /locus_tag="ACG930_002921"
     CDS             301..585
                     /locus_tag="ACG930_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520021.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="ACG930_002922"
     CDS             588..1004
                     /locus_tag="ACG930_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520022.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="ACG930_002923"
     CDS             complement(1141..1860)
                     /locus_tag="ACG930_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFQ0520023.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2522..2608
                     /locus_tag="ACG930_002924"
     CDS             2522..2608
                     /locus_tag="ACG930_002924"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFQ0520024.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2910..>3199)
                     /locus_tag="ACG930_002925"
     CDS             complement(2910..>3199)
                     /locus_tag="ACG930_002925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520025.1"
                     /translation="EYRRQRSDFISRKIVRLEKEKMEKFPYEYFQNLEKLEQAIQAIK
                     FDLTDEKLLEYKNMTPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1065 a          597 c          499 g         1038 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2881 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2941 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     3001 aacgatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     3061 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     3121 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     3181 ctttgccgtc tatactctc
//
LOCUS       DAZKPE010000150         3125 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000150 DAZKPE010000000
VERSION     DAZKPE010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.155"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            110..1381
                     /locus_tag="ACG930_002926"
     CDS             110..1381
                     /locus_tag="ACG930_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HFQ0520026.1"
                     /translation="MNVFDATLKRLEYIFEEFDKVYFSFSGGKDSGIMVQLANLVAEK
                     LDRNFDLLILNIEANYTATVDFIKKIEQLPRVKNIYHFCLPFFEDNNTSFFQPQWKMW
                     DPSEKEKWIHSLPKNAITLENIDDGLKKYYSLSNGNPDRFLRYFQNWYKEQYPQSAVS
                     CGVGIRAQESLHRHSAVTKGENKYKNRCWINITLEGNILFYPLFDWKVDDIWAATFKC
                     GLEYNYIYEKMYKIGYKYRDMRICQPFGLQQRKALNQFAELEPETWDKLVKRVSGVNF
                     GNIYGKTSLLGLNTSQKPSFMTWQRYSIFLLETLGLYSPLLMNHYYRKICILFAYYKN
                     KYNMDIQDMPDESKRKDWIKDERLWNDWKGIAKALEKNDFVLSTRNYSLTKKDEAELY
                     EMFKEYKDFLGINQLKGKRYENIVQKIGGMK"
     gene            1378..1803
                     /locus_tag="ACG930_002927"
     CDS             1378..1803
                     /locus_tag="ACG930_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520027.1"
                     /translation="MSEIDIKVYIPPYNKQNFYSLMGKYFAERVYRRKLPYLINTPST
                     IWFLLMNKERIIGFSSIQISNEFIDIGDVFVEDENDDTRKYLLEKVLFFIDKKCERKC
                     VRISLKKDQYLNNLKHYCFKQYRETKNYLFFRREINEQD"
     gene            1790..2323
                     /locus_tag="ACG930_002928"
     CDS             1790..2323
                     /locus_tag="ACG930_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFQ0520028.1"
                     /translation="MNKIDMPVLNVKMVPVEKIKSNNYNPNHVAEPEMELLELSILKD
                     GYTQPIVCYYDDKKDEYIIIDGFHRYLIGKSKLDLKELPLVVIDKPLEQRMSSTIRHN
                     RARGKHEIDKMSELVLLLVNEGWDDHKIGKELGMEKEEVLRLKQVTGLKSAFLNHEFS
                     ESWDEFVKKNYPKQKDE"
     gene            2457..2924
                     /locus_tag="ACG930_002929"
     CDS             2457..2924
                     /locus_tag="ACG930_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFQ0520029.1"
                     /translation="MKFCETKKVLNQLVADLSVFSVRIHQVHWYMRGERFLFLHPKMD
                     DLMEQINDQLDVISERLITLDGSPYSTLEEFFTNSKLEEEKGSWNKTIDEQIDYLLEG
                     YNYLVSTYEEGIETAGKEGDDCTEDIFIGSKSELEKEIWMLKAELGNSPELDK"
BASE COUNT         1222 a          319 c          563 g         1021 t
ORIGIN      
        1 tctatatgat ttgaatacta taagaaacaa caattgataa aattattgac aaagttttta
       61 aaggtattac cattgatatt gaacgcttat ttttttaggg ggatgagaaa tgaatgtctt
      121 tgatgctact ttaaagagat tagaatacat atttgaagaa tttgacaagg tgtatttttc
      181 atttagtggt ggtaaggata gtgggataat ggttcagtta gctaatctag ttgcagaaaa
      241 attagataga aattttgatc tattaatatt aaatattgaa gcaaattaca cagcaactgt
      301 tgattttata aaaaaaattg aacagttacc tagagtaaaa aatatttatc atttttgctt
      361 accttttttt gaggataaca acactagttt ttttcaacct caatggaaaa tgtgggatcc
      421 aagcgaaaaa gaaaaatgga ttcattctct tcctaaaaat gccataactt tggaaaatat
      481 tgatgacggt ttaaagaaat attattcatt atcaaatggt aatcccgaca gatttcttcg
      541 ttattttcaa aattggtata aagaacaata tccccaaagt gctgtatcat gtggtgtagg
      601 tataagagca caagaaagtt tacatagaca tagtgctgtt acaaaaggtg aaaataaata
      661 taagaatcga tgttggataa atataacttt agaaggaaat attttgtttt atcctttatt
      721 tgattggaaa gttgatgaca tttgggctgc aacttttaaa tgtggactag aatataatta
      781 tatctatgag aaaatgtata agattggata taagtaccgg gacatgagaa tatgtcagcc
      841 tttcggatta caacaaagaa aagcgttaaa tcaatttgct gaacttgaac ctgaaacatg
      901 ggataaatta gtaaaaagag taagtggagt taattttgga aatatatatg gtaaaactag
      961 tcttttagga ttaaatactt ctcaaaaacc ttcatttatg acttggcaaa gatattctat
     1021 ttttttacta gaaacattag gattatattc tcctctttta atgaatcatt attacagaaa
     1081 gatatgtatt ctttttgctt attacaagaa taaatataat atggatatcc aagatatgcc
     1141 agatgaatca aaaagaaaag attggataaa agatgaaaga ctttggaatg actggaaagg
     1201 gatagctaaa gctttagaaa aaaatgactt tgttttatct actagaaatt atagtttaac
     1261 gaaaaaagat gaagctgaac tatatgagat gtttaaagaa tataaagact ttttgggaat
     1321 aaatcaatta aaaggaaaga ggtacgaaaa tattgtacaa aaaataggag gaatgaaatg
     1381 agcgaaatag atattaaagt ttatataccc ccatacaata aacaaaattt ttacagttta
     1441 atggggaaat attttgctga aagagtatat agaagaaaat taccttattt aataaataca
     1501 cctagtacta tttggttttt gttaatgaac aaggaaagga taattggatt ttcttccatc
     1561 caaatttcca atgagtttat tgatattgga gatgtttttg ttgaagatga aaatgacgat
     1621 actcgaaagt atctattgga gaaggtttta tttttcatag acaagaaatg tgaaagaaag
     1681 tgtgtacgaa tttctttaaa aaaagatcag tacttaaata atctgaaaca ttattgtttt
     1741 aaacaatata gagagacaaa gaattattta ttttttagga gagaaatcaa tgaacaagat
     1801 tgatatgcct gttttaaatg taaaaatggt tccagtagag aaaataaaaa gtaataatta
     1861 taacccaaat catgtcgctg aacctgaaat ggagctttta gaattatcga ttttaaaaga
     1921 cggatataca caaccaattg tttgctatta tgatgataaa aaagacgaat atattattat
     1981 tgatgggttc cataggtatt taattggaaa aagcaaactt gatttaaaag aacttccttt
     2041 agttgtaatt gataagccat tggagcaaag aatgtcaagt acaattagac acaatagagc
     2101 tagagggaaa catgaaatag ataaaatgtc cgaattagtt ctactgcttg tcaatgaagg
     2161 atgggacgat cataaaatag ggaaagaact aggaatggaa aaagaagaag ttcttagatt
     2221 aaaacaagta acagggttga aaagtgcctt tttgaaccat gaatttagtg aatcatggga
     2281 tgaatttgta aaaaaaaatt atcctaaaca aaaggatgaa taagtggtaa agatttttat
     2341 aaacacgatt ttaatataaa cgttcatttt attgttgaca agatatattt gttatattaa
     2401 attatgtgta aatcagaatt atttctttta aaaaaattta aattaggagt gatattatga
     2461 aattttgtga aacaaaaaaa gtattaaatc aattggtagc cgatttaagc gtattttcag
     2521 taagaataca tcaagttcat tggtatatgc gtggagaaag gtttctattt ctacatccta
     2581 aaatggatga tctcatggag caaattaatg atcagttaga tgtaatttca gaacgactga
     2641 ttacacttga tggatctccg tattcaactc tagaagagtt ttttacaaat tccaaattag
     2701 aagaagaaaa aggctcttgg aataaaacta ttgatgaaca aattgattat ttattggaag
     2761 gttataatta tcttgtttcg acatatgaag aggggattga aactgcagga aaggaaggcg
     2821 atgactgtac agaggatatt tttattggtt ctaaatcaga gctagaaaaa gagatttgga
     2881 tgttaaaagc agagttaggt aactcacctg agttagataa atagatacag aacttcaagt
     2941 gaatggttat gatatttcct tgtgaatagg gagtgttttt cagtgtttct atgaatacta
     3001 taagtgagat tgataaaaaa acaaaaacat ctaaggagag atttatttct accttagatg
     3061 ttttttcact aagtgatctg tttcagtcga taaatataag tgcaggtaga ttttaacaac
     3121 taatt
//
LOCUS       DAZKPE010000151         3093 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000151 DAZKPE010000000
VERSION     DAZKPE010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.156"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            62..1231
                     /locus_tag="ACG930_002930"
     CDS             62..1231
                     /locus_tag="ACG930_002930"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFQ0520030.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(1498..>3093)
                     /locus_tag="ACG930_002931"
     CDS             complement(1498..>3093)
                     /locus_tag="ACG930_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520031.1"
                     /translation="KIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINRALSLESIFS
                     SPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTLITLFICHYV
                     MYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLGFIKLYDSKK
                     ESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIKLIKAAIVTL
                     LLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIGLTLLI
                     CLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRFMIFST
                     LFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEMNFQGTYSNE
                     QMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTFKSSKG
                     KTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSYTFFSKISLF
                     ISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         1158 a          483 c          455 g          997 t
ORIGIN      
        1 gatacaagct attttagctt tattctttct gtaaaaaaga aaggagacta aataaactat
       61 tatgaaaaaa ggaaaacatg ctaaaaaaag aaaatattca tttttaatga tcgttgtcgt
      121 gttgtttagc cttagtgcgt tctctacagg aactattctt ggatggcaat tttacaataa
      181 tgaacactct cagatagttg cccatgctca atcagctcaa aaaaagttga tactgactac
      241 caatgaacaa cagctcgttg aaaaaatcga tcaactatta agaaaaaatg attatattgg
      301 ctcaatttac gtaaagaaaa ataatcgcat catcatggaa aaaggctatg gctatgcgaa
      361 taaactcacg caacaaccaa atgatccttc tctttattat cagattggtt cggttcaaaa
      421 agcattgact actcttttga ttttaaaaca agtcgagcgt gggcaccttt ctttagatac
      481 taagctggct caattctatc cacaaattgc tggcagccag caaattacta tccgtgactt
      541 gctgtatatg cgctcaggct tgcaccgaac tgcttctcca accataccga tgactgatga
      601 agaagtcgtt caatttgcga ttcagcactt aaaatttaca gattatcaga cctctcatta
      661 tgattcattg aactttacca tattgactgg aattttgatc aaattaacaa atcaaccgta
      721 tgaaaaatta ttgaccgatg atatcatcga acctttagga ttacagcata caaaatttta
      781 tgaccaagtc aaaaattcat ccaatcatgc actatcctat caaatgtcta aagaggatga
      841 ttactttaaa ccactgacag aatctgaaac agagatccat aacgaattag ggactggtaa
      901 tatcagtatg tccgtctatg atttaaatac gctgtttaca caagttttat ctggaaaact
      961 agtttccaaa gacttactct tctcattatg gcgtgaaaat gcgaatggac atccatatag
     1021 tggtggggta tatagcggag ataattatat cctgtcgcaa ggaaatatcg actcttttga
     1081 tacatctgct atatttagca aagattcaca ggatgctatc atcatggaaa gcaatataaa
     1141 agctgacaaa actatcaaac tgcctactgc tgatctaaga aaccaaatct atgacctgat
     1201 ggaaggaact actaagttgg caaatagctg atatgatgaa aagatagcaa atactacttc
     1261 tttgaatagc atttgcttaa aaaaagtact cgactaaacg taggaaagag tgtgggacaa
     1321 atctaaaaat caatttttgc tacagacttt aattccaaat aaacagaaca gaaagaggtg
     1381 ttcttctttc tgttctgtcc aaattattct aagatttctc tttaccaaca ttatttgaca
     1441 aagggcctat taaatctaaa atagtatctt tagattgcta aaatatgtgc tagcaaatca
     1501 ttcatggctt gttcttattt ttaattttat gcaataaaaa agaagaacaa ttagcgtgat
     1561 tatagaaata aataatgaga ttttagaaaa aaatgtgtat gaatacctga ttgttacttt
     1621 atttattcca ctttcacttt ttactgtaac aaaaggacct ccttgtttta gtactgtagc
     1681 attttttgaa ttaacagtaa ccgttaatcc tttataccgg aatacaggta aaactattgt
     1741 tttgcctttt gaagatttaa acgtaaatgt aatttcatct ttatttggag aaaagctact
     1801 ataaataact tgaccatctt ctgtaacttg atggtttttc aaaagcaatt gatctttttt
     1861 atagcctata ggtacataat caaaattctc aaattcttca agtttatttt ccatttgttc
     1921 attagaataa gttccttgaa aattcatttc tttcaccatg ttaactactg atgaataatt
     1981 taaaattgaa atagctaata ttaataatag tataaaattt cttctccttg tataagaaaa
     2041 tttttccaac tgtggagaaa taaatagaga tactgaaaaa gatatgaaca atgttgaaaa
     2101 tatcataaaa cgccaaggag cttgaataat atttaaagga gtattttgta aggcaaacca
     2161 tggaaatatt tttgtacaaa gtagaataga tattataccc attatataag tgattttaga
     2221 taagattcct aattttttaa agttaaatgt tagtataatt aaacaaataa gcaaagttaa
     2281 gccaatacca aatgatagta attctgaatc tatacttcca atcaaaaact ctttacccag
     2341 ataaattgct cttttttgta atatatccac ataaggtcta ttcagatctt gatacaatgt
     2401 ctgctcaatc ataggaccta taaacgctag tgaaagaagt aaagtaacta tagcagcttt
     2461 tattaattta ataattaaga agatttctat tttctttttc cgataaaatt gaataattaa
     2521 agcaattata atcattacca tagtcatagc tacagaaaga acatgagtgt aaattaataa
     2581 agtcatgcta atcgccaaca taacccaaga ttcttttttt gagtcgtaaa gctttataaa
     2641 cccgagtaaa ataagaggaa gtattgacat tgcgagtaat tcccccattg cccctcgaag
     2701 aaatatttct acactcctaa aagaagatgt tgtatatata atagcgaaaa aggagctagt
     2761 aacatgtttt ttggtaattt catacattac ataatgacat ataaatagag taatgagcgt
     2821 aacaatataa agaaaaaggt tatagcctat tgctaaatta gtaaacttga tcaataaaaa
     2881 taaaggatat agagttaacc atgggtaaaa attatttact tgcatgccat atgatctaaa
     2941 cgtttcaaaa ttaatagggg agctaaaaat agattctaaa cttaacgcac gattaatgtg
     3001 aaatgccgta tcataaaagc caaatatttc catgttttta aatgctggaa ataaatataa
     3061 taaactaaca aatgcataaa ctataaatat ttt
//
LOCUS       DAZKPE010000152         3048 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000152 DAZKPE010000000
VERSION     DAZKPE010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.157"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(268..882)
                     /locus_tag="ACG930_002932"
     CDS             complement(268..882)
                     /locus_tag="ACG930_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFQ0520032.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1488..1865)
                     /locus_tag="ACG930_002933"
     CDS             complement(1488..1865)
                     /locus_tag="ACG930_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520033.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2165..3046)
                     /gene="galU"
                     /locus_tag="ACG930_002934"
     CDS             complement(2165..3046)
                     /gene="galU"
                     /locus_tag="ACG930_002934"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFQ0520034.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          918 a          640 c          468 g         1022 t
ORIGIN      
        1 ttctttcttg tctctttttc cactactttt tatttttctg acactacata ttcttataac
       61 tcatttctca taactgtgaa acaacttata aaaataacaa actttaaaca aaacaagctt
      121 aaaatcaaag atgatccatc ttaaaataac taaaacaaaa aaagtagtcg ttgttaatcc
      181 tcattaataa tcgttttctt tttttcaaac gctccatttt tatgtggaac attatttttt
      241 taaggaactt tgtcaacatg tggataacta ttttccactt gtgtcctgga ctagctgttt
      301 tgctgtaaaa tacaaaactt gctgcagcaa aaagatcgtt gcaagagagg ctgttccgca
      361 gatcgctgga tctagatttg gcaaagtcaa gactgcatca tgtaaattgg cgtggttgtc
      421 caaaaccaaa tcagcaaatt caaataatcg caaaccactg ctatgttgcg atttgatact
      481 tcgtgacaaa tcaaatccag taacaatgat taatggatga ccattttctt tgatccactg
      541 agctagttcg atgattgccg ggtttcttcc ttcattcgaa agaagaagaa aaatgtcttc
      601 tgatttgaca gaaagctgat caataattgc ctgtcctgca ccttctagcg tttcatagac
      661 acctccggct ggattttcaa tcaatatact tggtacaaga tccggggttt gatcccaaaa
      721 ttcaaatgct acaccactta gtgtgcggct agcatatatc tgcaatctac caccttgatt
      781 aatttgtttc gcgatccaag tgccagcttg aagcatcagc ggctcttcta tccttaattt
      841 ctcttccaat tggtgataat agtcaaaata acataaactc atttatctct cccgcctagc
      901 tatacttgac atgaatagaa acagctgcct aatctaagga agtacataaa aaaacagtag
      961 ttagacagta acacatgtgg tctttgctgt ttcaaacaca aaaaaggcat tgaacgaata
     1021 cgcccaatac cttgacatag caaataaaac aacgtgcaga ccatggaaaa tatctacata
     1081 ggggtagaat tttcacccta gattaggtac aataaattag gtcgatgcac tgcattgact
     1141 atggcaaaat gatcggtcag ggtgtatgtg tgtgactggt cattccctga ttcttagcgc
     1201 caactaaggg tcagggagcc tttttttatt cagctgtttc tatctgaatt tattgtaagt
     1261 aatctcttat ccaagtgcaa gcaagaaaat acaaaaaaac attggtatga tttatatata
     1321 tataaataac ataaaaaaag gaatggctta tcccgataca acaagcattc ctttaaaaaa
     1381 gattctttta tataagtgaa aaaagctttt ttccaccaat taaataaatc tctcatctca
     1441 atagtttatc cattatttta tctttttttg cgtataccta ctaaatatta ccgtcttctt
     1501 ctcgttcttc tactttgttc gagagaatct gtactagaaa aagtagttgt atgtctacct
     1561 tttctgccta tccgagactt tcttttcata tatgggatat aaatgattag atacagtaca
     1621 gcaaaaaata aagcaaatac gcaagcttcc caactaccta acgccaattc aaccatcaag
     1681 gtagcaaccc caacggatgc tgcataccag ataaaaatca gaaacgtttc tttttttctg
     1741 accatgcgaa acatgataaa tagactaata agcaatagtg gcaacacaaa tatccaattg
     1801 cttccttcca tcagccactt gagtatatca agcagcgact gtgcaacagc gactaatttt
     1861 cccatagtga acacacacct ttttttataa ttaaaaaatt cgccttttta ttctactatg
     1921 aatcttctgg cttggctttc atttctctta tgtaatcatt ttcttttata caacttaaaa
     1981 aaaaattaaa ccattagcat aatattttct gaatctattc acgaaagtct ttttctatct
     2041 ttcgttttcc acgactcaac tgatctagag tcaaaaaact aaaacgacag ttgcgcaaat
     2101 gacgcacaag ctgccgcttt aataacaaat agcctttcat tctcagcagg ccacttattt
     2161 ccagttaact ttctgttctt agctttttac tcaactggat aatatatgca cttaatgaag
     2221 tcccaatttc cgaatgttga agtccatatt caatatttgt cttcatatat cctaacttat
     2281 cgcctacgtc gtatcttttt cctttaaact ctctcgcata gaccgcctct gtctggttaa
     2341 gagtctgaag tgcatccgtt agctgtatct cgtttcctgc tcctggttct tgagtttcta
     2401 atatctcaaa tattttagga gtcagtagat aacgtccgat aatggctaaa ttacttggtg
     2461 cttttcccat ttcaggtttt tctacaaacc cttttactct gcaacgaccc ttttcgctat
     2521 ctgttttagg atcaataatt ccgtatttag atgtttcatt ttctggtaca cgcatgacgg
     2581 caacagcgga agcttgtgtt tcttcataat ccatcatcaa ttgttgagtc aatgggatat
     2641 catctttcat caaatcatcc cccagcatga cgacaaacgg ttcatttcct ataaatgctt
     2701 ttgcttgaag cacggcatcc cccagtcctc ttggatgaga ttgacggatg aagtgaagat
     2761 tgacttgagt cgtttcttca actaaagcga gtaattctgt tttttccttt tcccgcaaat
     2821 tgttttccaa ttcgatattt gcatcaaagt gatcttcaat gggtcttttt tcttttcccg
     2881 ttacgatcaa gatgtcttcg attcccgaat ccaatgcttc ttccacaata aactggatcg
     2941 ttggtttatc cacgattgga agcatttctt ttgccatggc ttttgttgcc ggcaaaaaac
     3001 gtgttcctag cccagcggca ggaatgactg cttttttgac cttcactt
//
LOCUS       DAZKPE010000153         2973 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000153 DAZKPE010000000
VERSION     DAZKPE010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.158"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            41..778
                     /locus_tag="ACG930_002935"
     CDS             41..778
                     /locus_tag="ACG930_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFQ0520035.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            792..1607
                     /locus_tag="ACG930_002936"
     CDS             792..1607
                     /locus_tag="ACG930_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFQ0520036.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1620..2267
                     /locus_tag="ACG930_002937"
     CDS             1620..2267
                     /locus_tag="ACG930_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0520037.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2283..2939
                     /locus_tag="ACG930_002938"
     CDS             2283..2939
                     /locus_tag="ACG930_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFQ0520038.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
BASE COUNT          937 a          496 c          636 g          904 t
ORIGIN      
        1 taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga ttaaatttga
       61 tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc tcgaattcga
      121 gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca cgatgcttcg
      181 ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg atactgactt
      241 gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg ttttccaaca
      301 tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac caatcaaagt
      361 gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga aaactgtcaa
      421 tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac agcaacgggt
      481 ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg aacctacttc
      541 tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat tggctcatga
      601 cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag tggcggatcg
      661 tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga gagacttttt
      721 cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca atcattgata
      781 ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta ggcattgctt
      841 ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt ttagagcgaa
      901 gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta tttggaatga
      961 tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa gcaatcacta
     1021 aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct aaaactcgga
     1081 ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg atcacagatg
     1141 aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa gctttgttgg
     1201 taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca acggttctag
     1261 cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat gcaaaaattt
     1321 tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag ggagacgcga
     1381 tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag tatgagttag
     1441 ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg caagaaaact
     1501 tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca tacgataaaa
     1561 tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg ggagaggcaa
     1621 tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag atcacattgt
     1681 tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg gcaatcttcc
     1741 aattatcaaa gaataaagta gtgagcgcct tagcaaaggc atatgtagaa ttttttagaa
     1801 acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt tattggttta
     1861 atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct gcttttattg
     1921 ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa gcaggactat
     1981 cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa gcattcaaaa
     2041 tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca tctattttag
     2101 caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt gaaacattca
     2161 ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg ctaccgttat
     2221 cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag gaggggaaat
     2281 acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg gaaggattaa
     2341 aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc ggtggtctga
     2401 caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt gtagtgattg
     2461 atattatacg gaatcttcca ttattattga tcattttctt cacttacttt gccttacctc
     2521 aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg atttttgagt
     2581 cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa ggacagatgg
     2641 aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc gtgttaccgc
     2701 aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg atcaaagata
     2761 cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt attatttatg
     2821 gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg tacttcgtgg
     2881 tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac agttattaat
     2941 agatgattct tttagcggtt gtggcaaact aaa
//
LOCUS       DAZKPE010000154         2962 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000154 DAZKPE010000000
VERSION     DAZKPE010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.159"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1368
                     /locus_tag="ACG930_002939"
     CDS             <1..1368
                     /locus_tag="ACG930_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520039.1"
                     /translation="SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIAL
                     TIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSK
                     QIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDS
                     IIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFL
                     FQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIA
                     AKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGE
                     SWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVD
                     VNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINK
                     KNENK"
     gene            1355..>2962
                     /locus_tag="ACG930_002940"
     CDS             1355..>2962
                     /locus_tag="ACG930_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFQ0520040.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLF"
BASE COUNT         1006 a          440 c          506 g         1010 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tt
//
LOCUS       DAZKPE010000155         2940 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000155 DAZKPE010000000
VERSION     DAZKPE010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.160"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            620..>2940
                     /locus_tag="ACG930_002941"
     CDS             620..>2940
                     /locus_tag="ACG930_002941"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520041.1"
                     /translation="MFYQRSEKKFKYAIKKKKGGGGAASFIIGAMFLGIGLISCPTVS
                     FASETTEINQSTEIQSTLNNSILKESNSEEKQNIDVSEDSAINKDLELASKATISESE
                     NSFGETTNNQENTNLSEDSIEVQPESIIQKEVLTDNDAIQQLEVHPHEDSDDAALVEN
                     QMTRVTEESIKSNTSQVDKDTTVLSNTTRDLVNLEDTAIENVTPQKTIKKDSISLLEE
                     NNSSSASRTLRRSVRSLDVQTGENFLEDWALPDNSNISGSLITQTGITYVGVKTDDPT
                     QLHLKMAYRAAATPASIDWIYLRVDPELTKYIEEINIKNTVNIGAQVGYQRYFEKVDT
                     NTLSNVNTFGTPTGVSDAYAQVDQKTGGIYRVLLDKFFIRIPGTNPKSRGALSGNWGV
                     FPSVPLEAERYEANIYIKLSKDVAELQQELGRDKFGVQLRLQGQSSSGVATIAKESLN
                     KNTIVDLSQEEPDENNSNWLNSPSVHTITTTYEGKQMGSDGQFSSILEGTDKSLIRVQ
                     NTIMNNLLYGTALDLGRPVSFNIEIDPQILNLVSDDDYITIWQVYRENSINHHDGGSN
                     APVMLKKNMFVDNKIKIEVNKDKAGQYGNGVYYVNAVESFMNTLSSSPFVGANFIDIP
                     VMPKSLIEDEDQLISAEIKTWFTDKKNDQERIVRNSLASSYINLFPTTINFYDYSTKD
                     TEQLLKLRESTYLVSTFGQEINGMDMGETYEISNYEFVTADPESLIITQKDGNIINLY
                     YKKLSSDAEFYEPEVEKEEVNYGETIDLTDNVT"
BASE COUNT         1073 a          394 c          527 g          946 t
ORIGIN      
        1 gtatattgat attattatca tgtttatttt aggaagaata ctatgagtta agtttttaat
       61 aagaaatgtc gagtttatga accttttttc aaagttgaaa aaatttcttt atttgataat
      121 ggcgatcaac atcttttaga atggatgcaa tggttaaact gattgttgag tatataatca
      181 cttgtttgtt tttatttatc ttttccccac tatatggtta atagtcagcc actttagaaa
      241 gagttttagc tgttttttac ttgaggaaca tcattttatt ggcagtctta tttgacttat
      301 taagtgaatt tatattaaaa aaattcgttt ttactcataa taatctctac taagattcct
      361 cctttatttg agtatcattc tcatttgatt ataaattaaa tccttccctt tattattatc
      421 aacgagaaaa aaggttaaat gaatacaaaa gaaatagatc ttttgtgact aataaaaagt
      481 gaacgttcat attgaaaata ttataaattt aatttaacat ataaattgag aaagggaatc
      541 tattctaacc tttcttataa aatgaacgtt cgtttttagg atttcttttt gataactttt
      601 tatgttagga ggataaagta tgttttatca aagaagcgag aagaagttta agtacgcaat
      661 taaaaagaaa aaaggaggag gtggagcggc ttctttcatt atcggtgcaa tgtttttagg
      721 aataggatta atttcttgtc ctacagtttc ttttgctagt gaaacaacag agataaatca
      781 atcaactgaa atccaatcta ctttgaataa ttctattcta aaagaaagta attcagaaga
      841 aaaacaaaat attgatgtgt cggaagatag tgctataaat aaagatctag aactagcttc
      901 gaaagcaacc atttctgaat cagaaaattc atttggtgaa actactaaca atcaagaaaa
      961 tacaaattta tctgaagata gtattgaagt tcagccagag agtattattc aaaaggaagt
     1021 cttgactgat aatgatgcta ttcaacaatt agaagtacat cctcatgaag atagcgatga
     1081 tgctgcttta gttgagaatc agatgacaag agttacagaa gaaagtataa aaagcaatac
     1141 ttcacaagta gataaagata cgacagtttt atctaataca acaagggact tagttaattt
     1201 agaagatact gctatagaaa atgttactcc acaaaaaacg atcaaaaaag atagtatttc
     1261 tttattagag gaaaataatt catcatcagc atcaagaact ttacgtagaa gtgttaggag
     1321 tcttgatgtt caaactggag aaaacttttt agaagattgg gcactaccag acaattctaa
     1381 catttctgga agtttgatta ctcagactgg aattacttat gtgggtgtaa aaactgatga
     1441 tcccactcaa ttacatttga aaatggctta cagagctgca gcaacgcctg cttcaattga
     1501 ttggatttat cttcgtgtgg atccagagct tacgaaatat attgaagaaa ttaacataaa
     1561 aaataccgta aacatcggtg cacaagttgg gtaccaacga tattttgaaa aagtagatac
     1621 taatacattg agcaatgtaa atacttttgg aactccgaca ggtgtaagtg atgcttatgc
     1681 acaagtagat caaaaaactg gcggaatcta tcgtgtgtta ttagataaat ttttcatacg
     1741 tattccgggc acgaatccta agagtcgagg cgcgctatct ggaaactggg gggtatttcc
     1801 atctgttcct ctcgaggctg aaagatatga agcgaatatc tatataaaat tatcgaaaga
     1861 tgtcgcagag ttacagcaag agcttggaag ggataagttt ggtgttcaac ttcgtttaca
     1921 aggtcaatca agttctggtg ttgcaactat tgctaaagaa agtttaaata agaatactat
     1981 tgttgatctt tcacaagagg agccagatga aaataattca aattggttaa actcaccatc
     2041 tgtccataca attactacca cttatgaagg aaagcaaatg ggaagcgatg gtcagttcag
     2101 tagtattctc gaaggaactg ataaaagtct gattagagtt cagaatacga tcatgaataa
     2161 ccttttatat ggaacggcac ttgatttagg tcgacctgtt tcatttaata ttgagattga
     2221 tccacaaata ttaaatttag tttcagatga tgattatatt acgatttggc aagtatacag
     2281 agaaaatagt atcaaccatc atgacggtgg atcaaatgca cctgtcatgt tgaaaaagaa
     2341 tatgtttgta gataataaaa taaaaattga agtcaacaag gataaagctg gtcagtatgg
     2401 aaatggagtt tactacgtta atgctgttga gagctttatg aatactttga gttcttcacc
     2461 atttgttggt gcaaacttta ttgatattcc tgttatgcct aaatctctaa ttgaagatga
     2521 agatcaattg atatcagcag aaattaaaac atggtttaca gataaaaaaa atgatcaaga
     2581 gagaatagta agaaactcac ttgcttcaag ttacattaat ttattcccta ctaccattaa
     2641 tttctatgat tattcaacca aggatacaga acaattattg aagttacgtg aatcaaccta
     2701 cttagtttct acgtttggtc aagaaattaa tggaatggat atgggggaaa catacgaaat
     2761 tagtaattat gagtttgtga ctgccgatcc tgaaagttta ataatcacac aaaaagatgg
     2821 aaatatcatt aatttgtatt ataagaaact ttctagtgat gctgaatttt atgaaccaga
     2881 agtagaaaaa gaagaagtca actatggaga aacgattgat ttgacggata atgtaactaa
//
LOCUS       DAZKPE010000156         2875 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000156 DAZKPE010000000
VERSION     DAZKPE010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.162"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..448
                     /locus_tag="ACG930_002942"
     CDS             131..448
                     /locus_tag="ACG930_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFQ0520042.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(539..904)
                     /locus_tag="ACG930_002943"
     CDS             complement(539..904)
                     /locus_tag="ACG930_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520043.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1112..1594
                     /locus_tag="ACG930_002944"
     CDS             1112..1594
                     /locus_tag="ACG930_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520044.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1791..2681
                     /locus_tag="ACG930_002945"
     CDS             1791..2681
                     /locus_tag="ACG930_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFQ0520045.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          996 a          446 c          546 g          887 t
ORIGIN      
        1 taactatgca ctgtaacgat aatgctgcta aaatatcttt ttacgaaaaa catcacaagg
       61 aaaaacttaa ctatggtatt atctaaacat aattttttcg gtatttaata tttaattagg
      121 aggtaatatt ttgctttttt atagtaattt tatcttaata gtagcgatat tattacttct
      181 gaatatatgg atttttgata ggagtagaaa ttcaagtata ggttttagaa ctaaacgaag
      241 tttgtcttct aaaaaaaatt gggtatactc acaaactatt ttttatggag gaattgtttt
      301 aattagttta ctttcttcaa cactttattc tttgaatatt atagatgttt ccacctcaaa
      361 ttcaatatct attattggaa tcattattgc tgcaattatt acacaactgt ttttagtgtt
      421 tggagagaag aaaagaagta aaaaatagaa aaactagtga tagttttggt gatataagaa
      481 aaacatatat gtataaaaag aagaaagtag cttctctttg tacatatatg gtttgttttt
      541 atggatgccg agctttttta taagataagg ctaccgccca taacgaccca aggatttgtg
      601 gaactaagta aatacctgca agaagcaaga tcagctgggt cggttttaaa ggatgataga
      661 agtaacgcca ttcagtaaaa ttggcgcaaa ataaatagga agtgacagta gatataatat
      721 tggcaatgaa taaagatata atacgcctgt tcctttgaaa ataatatcca gcaaaaagag
      781 ataaaaatat caatgtgatg aacccgctta cggaatgata acgaaaatca agcagtaagg
      841 cgaaatgcac ataaggaaca aaagataaaa gcaacggaag gtttttccag caagttttta
      901 tcatctttca tcaccaccta acaagtgtta ttattttgtt agttttattg taaattgaat
      961 cctgcaataa tcaattactt tttcattatt tctagattaa atgaataaac tctcatgcca
     1021 ttatctctaa aaaaaaagtt tttcccccta atttttttag atagaaaatt gtatagtatg
     1081 atgagagaaa aagtagtttg ggggaacgtt aatgagaaga aaagcagtaa tcgatcggct
     1141 ttatttattt ttttggtttt ttcctatcgt tttgctacct tttacatggg taaatgctgt
     1201 tgtacaaggt gcggagatat taggcctgat ccaaggaagc ggatttgtgg tttctaggaa
     1261 ttttccagct ttgattgttt tctatttagt gataagtgta ggtctcttat taccaaaatc
     1321 tctgatcaat cactacaatt ggcagctgct ttacttttct tgcttattag tatttacatc
     1381 tatgttttct ttgctgcctc gcttgattat cggccctaat ggtttgagcg agagtggatt
     1441 gaaggattta gcttattcct ccatgtattt cttgacgatc aaaccatggt tctatttagt
     1501 aattgcctca tttattcttg caacattttt ttacttctgg acagaaatca ggataaaaag
     1561 tgaacgatct gtatctataa aaaataacta ttgatggtgg atcatcagta aaaaaacata
     1621 tgagctgcgt aaaatgcatg tttctcatat gcttttttta ttattatgta aagaatgcga
     1681 aaaacgttta catgattttt acataactta actatatttt tacagcaacc atacgaggga
     1741 tttacagtcg actgataaac tttagttgta aataagaaag gagcaataaa atgaaaaaag
     1801 tattgtttac tctaggtatg atgggaattc ttttagccgg atgcggctca ggatcaggaa
     1861 atacagatgg ctctgccaca caaaataatt caagtgactc aaatgaacaa gtaaaaatcg
     1921 ttgcggtagg ttcgacagca ttacagccgt tagtcgatgc agcacaagaa agctttgtac
     1981 aagaaaatcc aaattatcaa atctctgtac aaggaggagg aagcggaact ggtttgagcc
     2041 aagtcgaagc tggagcagtt actatcggaa actctgatgt atttgcagaa gaaagagacg
     2101 gagttgatgc ttcaaaatta gtggatcata aagtagcagt ggtcgggatg gcaccaatcg
     2161 tcaataaaga tacagatgtc aaagatatca ccaaacagga attgattgat atctttacag
     2221 gaaaaatcac taactggaag gaagttggcg ggaaagatca aaaaatcaac gtcgtgaacc
     2281 gtgcaaacgg cagcggtacc cgcgcgacat tcgaaaaatg gggactggat ggtgctaccc
     2341 ctgtgcagtc ccaagaacaa gattcatcag gaacagttcg gcagctggta agtcaaacac
     2401 caggagcaat cagctattta gctttctcat atctcgatga ttccacacaa gcactaagta
     2461 tcgacggtgt agaaccaaaa gaagagaatg tagcagataa cagctgggga atctggtcat
     2521 atgaacatat gtacacgaac ggaaaacctt cccctgaagt ccaaaaattc ttagactaca
     2581 tgatgacaga agaaatccaa gaaggacctg tcaaagaatt gggctattta ccaatcacaa
     2641 tgatggaagt agaacgtgat cacgaaggaa atatcaaata actagcagat aaacatgcca
     2701 cggtagtcgt tactattaag gaaaaatcaa ctatgtttcc ccacatatac atttttcctt
     2761 taattgtgaa aaatagttcc tcatattttg ccgttttttg agctaatacc gagggtcagc
     2821 tgattgaaca ccgtttattc gaaaaaaaga gctacgacat agaactgtcg taact
//
LOCUS       DAZKPE010000157         2851 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000157 DAZKPE010000000
VERSION     DAZKPE010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.163"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            554..2104
                     /locus_tag="ACG930_002946"
     CDS             554..2104
                     /locus_tag="ACG930_002946"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFQ0520046.1"
                     /translation="MSDKNTYARRSQRHKQEPDSCENTNQLNEAVKPQTGNENKQPKI
                     PKKKSNYSKYIFALFTALILVIVVTGGYIVYTLKQQEAEAQAKYETAAKNLMASIQEE
                     QDQSGISTKIDTINDGENKCLVYRPVDENTVPFKNANQLLDELAQKQQKKHREKEVLT
                     VARIKATAISSKVNQYRIEADSFIWDRSKENFKKPDSISEKDIYIFKKTGKEITNKDL
                     FPDEGSLLGIQQVIQQSILDQAKEPEKIIDAVLTMDRISYDSKMTYTPDELTIVLPKN
                     STGTSKVTLKYKDIAPFIDTDLVSQESIKDTLPALDENKKYVALTFDDGPNNSSTLDL
                     LNILKTDNVKATFFMLGQMVDQNPDVAKQVHDEGHEVACHSYSHPQLNTLSTDELQSE
                     INKANKAIFKATGVLPRNIRPPYGAIDKKSAETIGMPIIQWDIDSQDWKSKNPRAINN
                     VVKQNVYNGAIILIHDIHPESVKAIPNMISMLKNKGYEFVTIDQLLSGKQKPLHQYFG
                     MNDERLVD"
     gene            2389..2608
                     /locus_tag="ACG930_002947"
                     /pseudo
     CDS             2389..2608
                     /locus_tag="ACG930_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1101 a          444 c          464 g          842 t
ORIGIN      
        1 agtcttcttt gatagattgt taaagggaac ttaacaaagt aataagatgc ataatcaaat
       61 gcacaaaaaa caaaaaaaga agtttcttcg aatagaaatt ctgaaataac atcctttcgc
      121 ctaatagtga ataatttaaa taaagagaaa ctggctacac tatcaaagca agtgattctg
      181 tttagctaat tactaataat taaagtatta aaatagtatg tttaatcaaa tagaacaaga
      241 ttggataata gtttatattt ttaatcctag accattattg gtatttcaaa gactacaacc
      301 atactaatta atctatcgaa tggtacaatt tcaaaaacta aaatcaaaac tagtgattct
      361 aatgttatca aaactgagtt gaaaattaag tagccacaat atctaaagtg gtgaggaatt
      421 agcgataatt actacgccga aagtaaaaga ataatagaaa aaactttcct taaaaattat
      481 ctatgaattc gttttcatta taattgcgct gttttatttt actttatgat gataaatgga
      541 gggataaagt catatgtctg acaaaaatac ctatgcacgt cgtagccaac gtcacaaaca
      601 agaacctgat agctgtgaaa atacaaatca attgaatgaa gctgtaaagc cccaaaccgg
      661 aaacgaaaac aaacaaccaa aaataccgaa gaaaaaatct aattatagca agtatatatt
      721 cgcattgttt accgcactta ttctagtaat tgtcgttact ggcggctata ttgtttatac
      781 attaaaacag caagaagcag aagctcaagc caaatatgaa actgctgcaa aaaatctcat
      841 ggcttcaatc caagaagagc aagaccaaag tggaatttca acgaaaatag atactataaa
      901 tgacggagaa aataagtgcc ttgtttaccg tccagttgat gaaaatactg ttcctttcaa
      961 aaatgcaaac cagctcttag acgagcttgc tcaaaagcaa caaaaaaagc atcgtgaaaa
     1021 agaagtgctc acagttgcca gaataaaagc aacagcaata tcttctaaag ttaatcaata
     1081 tagaattgaa gcagatagtt ttatctggga tcgcagtaag gaaaatttca aaaagccaga
     1141 tagtatttct gagaaagata tctatatttt caaaaaaact ggcaaagaaa tcacaaataa
     1201 ggatttgttt ccagatgaag gaagtctctt aggtattcaa caggtgattc agcaatccat
     1261 acttgatcaa gccaaagaac ctgaaaaaat cattgatgct gtattaacaa tggatagaat
     1321 ttcttatgat agtaaaatga cttatacacc tgatgaattg actatcgtct taccaaaaaa
     1381 ttcaactgga acttctaaag tcactctaaa atacaaagat attgcgccat tcattgatac
     1441 agatctggtt tcgcaagaaa gtataaaaga tacattacct gcattagatg aaaataaaaa
     1501 gtacgtcgct cttacttttg atgatggtcc aaataatagc tcaacacttg atttgttgaa
     1561 tatactaaaa acagataacg tgaaagctac ttttttcatg ttaggacaga tggtggatca
     1621 aaatccagat gttgcaaaac aagtccacga cgagggtcat gaggtagcat gtcactcgta
     1681 ttctcatcca caattgaata cactttcgac agatgaatta caaagtgaaa taaataaagc
     1741 taataaagca attttcaagg ctacaggcgt cttgcctcgc aatatccgtc ccccttatgg
     1801 cgctattgac aaaaaaagtg ctgaaacaat tggcatgcca attattcaat gggatattga
     1861 ctcacaggat tggaaatcaa aaaatcctag agcaatcaat aatgttgtca aacagaatgt
     1921 ttataatggt gcaatcatct taatccacga tatccatcct gaatcagtta aagccatacc
     1981 aaatatgatc tccatgttaa aaaataaagg gtacgaattt gtgacgatcg atcaactatt
     2041 gtcaggaaaa caaaaaccat tgcatcaata ttttggtatg aatgatgagc gactagtaga
     2101 ctaactgtaa ttagattgag tggtatttga agaaattata tttgtagttt ccttatttga
     2161 tgaaaagtca tgtaaaacaa attaataaag agtattaagt atactaactg ttgtaagtat
     2221 acttaatact cttttagtta ttaactttag ttagtctcgt tagcgtagcg tacgaaacaa
     2281 aaaaacacgc atttctgtgc gtggacgaaa tagctttagc gataaaaaac tcctttcgat
     2341 atactaataa tggctactaa ccgcatatca gatcgaaagg agtttctaat gtttaccgac
     2401 gataaaagtg tagcacatac gagatgtcat attttcttta cccaaagtat cgacgaaaag
     2461 tgatttatgg aaagttaaga gtaggtattg gtcagatatt aagaaaattg tgtgagatga
     2521 aaaatattga aatcattaaa gctcatgtta tattcatttg ttagtaagaa taacgtcaaa
     2581 aattagtatt tccagtttta tgggttacta aaaagacgtc actgatcaat ttagaaaggt
     2641 aaatatattc tggtaataaa gatagactga accccgtaaa aacctcattg caacgaatca
     2701 aggaaagacg cttttgcttc tcccttgatt gggcacattc tttgattttg atttttgata
     2761 ttgattatat cttttaattc gccatagtta tttatacaat aaagaactaa attttctaag
     2821 aatagacttt ctagattctt tattttcagc t
//
LOCUS       DAZKPE010000158         2811 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000158 DAZKPE010000000
VERSION     DAZKPE010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.164"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            66..773
                     /locus_tag="ACG930_002948"
     CDS             66..773
                     /locus_tag="ACG930_002948"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFQ0520047.1"
                     /translation="MKKQIFLDAISGGLIVSCQALPGEPFYKEEGGLMSYFALAAERA
                     GAVGIRANSVRDILEIKEKVSLPMIGIIKRDYPPEEPFITATMREVDELVATGVEVIA
                     LDCTLRKRHDNLSINTFITQIKEKYPEQLLMADISTFEEGKNAYEAGVDFVGTTLCGY
                     TNESRKQEGPAIDLMKQLVQAEICVIAEGKIHTPEQAKKIRELGVSGIVVGGAITRPQ
                     EIAERFVNALKEEEKNV"
     gene            766..2268
                     /locus_tag="ACG930_002949"
     CDS             766..2268
                     /locus_tag="ACG930_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFQ0520048.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPIL
                     AQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVSYLVYTATI
                     SGFLELFSVKDATLDTGVVGSIAIGGIVAFLHNRYRKIELPQFLGFFGGSRFIPIISS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEHIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTESVAGITVSGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGLAWAIIYFIVFTFFL
                     KKFKVAIPGMIEEKEVVSEINLNKNTSLHEESLMIIKALGCEENIESVEACATRLRVA
                     VKNGQNVDKQAIKQLGATAVFEVKGGIQAVFGGKADLLSQEINQILKRDN"
     gene            2280..2759
                     /locus_tag="ACG930_002950"
     CDS             2280..2759
                     /locus_tag="ACG930_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFQ0520049.1"
                     /translation="MIKFLRKKKQVELFSPCSGKVIPISEVNDPVFSQKLLGEGFAVI
                     PEEQTIYAPLAGQVTTIFPTKHAISIKSNSGIDYLIHIGIDTVELEGKPFSILVDEKE
                     YITPENPLVKVDFKQLELAKKDSSVIICFTESSQIDNLDLYTGRVLHGVLCGYLNLS"
BASE COUNT          845 a          418 c          588 g          960 t
ORIGIN      
        1 gcgcgtgcta tattttattt ggagttatta tccgaaaatt aatttaaagt ggagtgttta
       61 ggagaatgaa gaaacaaata tttttagatg caatttcagg tggactgatt gtttcttgtc
      121 aggcattacc tggtgaacca ttttataaag aagaaggagg tcttatgtcc tattttgctc
      181 tagctgctga aagagctggt gcagttggta tccgagcaaa ttctgttcga gatattttag
      241 agattaaaga aaaagtttct ctacctatga ttgggataat taagcgagat tatcctcctg
      301 aagaaccatt tattaccgca acgatgcgtg aggtcgatga attagttgct actggtgtag
      361 aagttattgc gctagattgt acgctgcgca aacgccatga taatttgtct atcaacactt
      421 tcattactca gatcaaagaa aagtatcctg aacaattatt aatggcagac atctctacct
      481 ttgaagaagg taaaaatgcc tatgaagctg gcgttgattt tgtcggaacc acgttatgcg
      541 gatatactaa tgaaagtaga aagcaagaag ggccagcgat tgacttgatg aaacagctcg
      601 ttcaagcaga aatttgtgtt attgcagaag gaaaaatcca taccccagag caggcaaaaa
      661 aaattaggga attaggtgtt tctggaatcg tagttggtgg cgcgatcact cgtccacaag
      721 aaattgcaga acgtttcgtc aatgcattga aggaggaaga gaaaaatgtt taaaaaattt
      781 tcacaactag gtcgggcatt tatgttgccg atcgctattt tacctgttgc tggtttactt
      841 ttaggtcttg gcggtgcact gacaaatgaa agcgccataa atgcttatcc catattagct
      901 caaccgtggc ttcatacgat tttgagtatc atgagttatg ctggtaacgc cgtttttgct
      961 aatttagcat tgatatttgc gattggtatc gcagtggggc ttgcaaatgg tgacaaagga
     1021 actgctggtt tagctggtgg tgtttcttac ttagtttata cagcaacaat tagtggtttt
     1081 cttgaattat tttctgtcaa agatgcaact cttgatactg gagttgtagg ttcaattgcc
     1141 attggcggaa ttgtcgcatt tttacacaat cgctatagaa aaatagaatt accgcagttt
     1201 ttaggattct ttggtggttc acgttttatt ccaattattt ctagtttggc tgcaattatt
     1261 attggttcct tcttttatct aatttggcca ccgattcaga atggattagt tgttgctgga
     1321 gagcatattg ctcaaatggg gagtctagga acatttcttt atggattttt acttcgttta
     1381 actggtgctg ttggtcttca tcatacaatt tatccacttt tctggtacac ttcgttaggg
     1441 ggaactgaga gtgtagcggg aattacagtt tctggggcac aaaatatttt ctttgctcaa
     1501 ttagctgatc cgaatcacac aggcttattt acttatggga ctcgtttttt tgctggaaga
     1561 tttgccacga tgatgtttgg ccttcctgct gcttgttatg cgatgtatcg tgcaattcct
     1621 aaaaaaaacc gtaagaaaaa tggcggtctt tatttcagcg gtgcattaac ttcgttttta
     1681 acaggaatca ctgagcctgt agaatatatg tttctgtttg tggctccatg gctttatgtc
     1741 atccatgcat ttttagacgg cctatctttt tattttgcgg atatcctgaa tattcgagta
     1801 ggaaattctt tttcaggtgg actaattgat tttctattat ttggtgtact tcaaggaaat
     1861 gacaaaacta actggcttaa attgattcct tttggacttg cttgggctat tatttacttt
     1921 atcgttttta ctttcttttt aaaaaaattc aaagtagcga tccctggtat gatagaagaa
     1981 aaagaggtag tctctgaaat taacttgaat aaaaatactt ctttgcatga agaatcttta
     2041 atgattataa aagcacttgg ctgtgaagag aatattgaat ctgttgaagc ctgtgcaact
     2101 cgcttgcgtg ttgctgtgaa gaatggacaa aatgttgaca aacaagctat aaaacaatta
     2161 ggtgctactg cagtttttga ggtaaaaggt gggattcaag cagtttttgg aggaaaagct
     2221 gatttactta gtcaagaaat caatcaaatt ttgaaaagag ataattagga ggaatttata
     2281 tgattaagtt tttaagaaag aaaaaacaag tggaactatt ttctccatgt tcgggaaaag
     2341 ttattcctat atcagaagta aatgatccag ttttttcaca aaaattatta ggggaaggtt
     2401 ttgctgttat tccagaagag cagacaattt atgctccttt agctggtcag gtcacaacta
     2461 tctttccaac aaaacatgct attagtataa agagtaattc aggaattgat tatttgattc
     2521 atattgggat agatacagta gaattagaag gaaaaccttt ttcaattctt gttgatgaaa
     2581 aagaatatat aacacctgaa aatccactag ttaaggttga ttttaaacag cttgaattgg
     2641 ctaaaaaaga ctcatcagta atcatttgtt ttactgaatc tagtcaaatt gataatctcg
     2701 atttatatac aggaagagtt ttacatggtg ttctttgtgg gtatttaaat ttatcataat
     2761 gattaatagt tagattaata agatctaatt attagaaact cattggtgaa g
//
LOCUS       DAZKPE010000159         2799 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000159 DAZKPE010000000
VERSION     DAZKPE010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.165"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..364
                     /locus_tag="ACG930_002951"
     CDS             <1..364
                     /locus_tag="ACG930_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFQ0520050.1"
                     /translation="VEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVN
                     SVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTIT
                     YEQVLSIFNSYLLFNGRK"
     gene            534..794
                     /locus_tag="ACG930_002952"
                     /pseudo
     CDS             534..794
                     /locus_tag="ACG930_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            957..1622
                     /locus_tag="ACG930_002953"
                     /pseudo
     CDS             957..1622
                     /locus_tag="ACG930_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            1658..1903
                     /locus_tag="ACG930_002954"
     CDS             1658..1903
                     /locus_tag="ACG930_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFQ0520051.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2006..>2799
                     /locus_tag="ACG930_002955"
     CDS             2006..>2799
                     /locus_tag="ACG930_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0520052.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLY"
BASE COUNT          981 a          425 c          538 g          855 t
ORIGIN      
        1 tgttgaagaa ggattctaca agcgtacctt ggatattcac cgaacactag ggttgctctt
       61 gcacactcaa gtctcgattc agcaattgct taagctgcca gcggaatgct ttcatcctaa
      121 accaaaagta aacagtgtct taataaaact tacccgccat accacagatg ttccagataa
      181 atattggaag ctatatacgt actttgtttc aaaatgggtc aatcgagaat atcgtcaact
      241 gtttactaaa aatcagtttc atcaagcaat gaaacacgcc aaagtaaaca atttaagtac
      301 cattacttat gagcaagtat tgtctatttt taatagttat ctattattta acgggaggaa
      361 ataattctat gagtcgcttt tttaaatttg gaaagttaca cgttactaaa gggaatggag
      421 ataaattatt agatatacta ctgacagctt ccaagaagct aaagaggtcc ctagcgccta
      481 cggggaattt gtatcgataa ggggtacaaa ttcccactaa gcgctcggga ccccttgtag
      541 gaaaatgtcc taagtgtggc aacaatattg tattaaaaaa atcgttttat ggttgttcaa
      601 attatcctga atgtaagttt actttagctg aacattttag aaagaaaaaa ctaaccaaaa
      661 cgaatgtaaa agaattactg gagggaaaag aaaccctggt aaaaggaatc aaaaacaaag
      721 agaaaaagcc ctacaatgcc gttgtaaaaa ttggggaaaa gggatatatt gattttatct
      781 ctttttcaaa ataaacatgg ggctgaccca aaagtagctc ctatatgaaa aatagaggtc
      841 tttccattta gatagtagtg gaaagacctc tatttatctt ttgaaagtga atacaaaaat
      901 aaagcacact ctgctataat ataggtgatt aatccatttg agagaggtgc tttatcatgt
      961 atcaaaatta taccataaac caactttgtt tgcctataga tcttgaaatt aaattagaag
     1021 aaaatgattt tgctcatgcc attgtgcagt ttgttgactc tattcccgat gaagtctttc
     1081 ttccttatta tcaatctatg ggtagacccc aatatcatcc tcgtatgcta ctttccatta
     1141 ttctttgtgc ctatattcaa ggggtttatt cgggccgcca aatacaaaat atgctgatag
     1201 atagtattcg gatgcgctac ttatctcaag agcaattccc taactttcgt actattaatc
     1261 gttttcgcgt tcatccgatt atgaacgata ttctagatca ttcatttgtt caatttcgtg
     1321 agctactggt tcaaagtggc ttaatcagtg gcagtgctct atacattgat ggtacaaaaa
     1381 ttgaagcgga tgcgaataaa tactctttcg tttggaaaaa aagtatttta aagtataagg
     1441 atagccttga tcaaaaagcc cttgaaaact accaacaaat ggtggaaaca aaaatcttac
     1501 ctgagttaat agatgattta aaggatgaac tttctataga agagattgaa aggattcgtc
     1561 aatctttgga agaaaaggaa aatcaattaa ttgaagcgat tgaccaaacc gaaacagtag
     1621 aagggggctg acccattatt aataaggagt ggacaacatg attgatgtaa atgagctatt
     1681 ggaagaagct attagagaaa ctgaaaatct aaatgatggc gaagtttttc ttgttaaaga
     1741 tttattcaag ggatatgtgg ggaataggat acccagaaag gatcgacttc tgcttggaac
     1801 gttattttta aaccatgtta gcaaaatgaa tggtaattta aaggctattg aaaagacttc
     1861 atctaatcag cagaggtata aaaagacaat tgataagttt taactatctt ttgtgaaatt
     1921 aaaaaaatta taaatatgtt gagtagaagc aaaagatttg gcttggaatt tttacagcag
     1981 tgaatcgata aaaggagcat gcttgatggt agataatatt attaaatcag tagcagagaa
     2041 attatcctct ctgtcttata tagaaggtat tgttttaggt ggttcacgtg caaggggcac
     2101 ccatacagag gattcggata tagatatcgg catctattac aattcagaat catttgacat
     2161 aaatactatt aatcaattcg ctacaaagct ggatgatgag catagaaata accttgttgt
     2221 acctcccgga gcatggggtg attggattaa tggcggcgga tggttagtca taaacgggta
     2281 tcatgtggat ttaattttac gtgatattaa acgtgtggaa caaataatga aagatacaga
     2341 gcacggaatt gttactgcca attatcagac tgggcatccc catggttata ttagtgcaat
     2401 gtatcgagga gaattagcga ttagcaaaat actatatgct aagaatgaaa gcttatgcga
     2461 attaaaaaaa caggcagaaa cttatcccaa tgctttgcag aaaagtttag ttaacttttt
     2521 tatgtttgaa gcagggttct ctttaatgtt tgtaaaagca aattcgggaa cagacgataa
     2581 atattatatt gcgggtcatg tttttcgtat agtttcatgt ttaaatcaag tgttatttgc
     2641 atgtaataat gcttattgta tcaacgaaaa gaaagctata aaactgcttg aaacttttga
     2701 acataaacct gaaaaatata ccgagaaggt aaatcatatt tttgaagtac tcggtatctc
     2761 actttttgaa tgctacgaca tgaccgagaa gctttataa
//
LOCUS       DAZKPE010000160         2797 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000160 DAZKPE010000000
VERSION     DAZKPE010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.166"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            165..800
                     /locus_tag="ACG930_002956"
     CDS             165..800
                     /locus_tag="ACG930_002956"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0520053.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            907..2145
                     /gene="mef(H)"
                     /locus_tag="ACG930_002957"
                     /gene_synonym="mefH"
     CDS             907..2145
                     /gene="mef(H)"
                     /locus_tag="ACG930_002957"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFQ0520054.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            2372..2791
                     /locus_tag="ACG930_002958"
     CDS             2372..2791
                     /locus_tag="ACG930_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFQ0520055.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
BASE COUNT          936 a          384 c          500 g          977 t
ORIGIN      
        1 cagtatgaat tgacaccgca taaggaaagc aactggaaga ttgtagaata aatgaaaaag
       61 gcttgcattc tgcattttta taaaattgca agtctttata ttgacaagca taaaatacta
      121 agatatactt taatcagacc aacggtttgt attggaggta agttatggca cgaaataaat
      181 atccagaaga aacagtaaaa ctcattttag atgtttctac aaaaatgttt tgtgaaaaag
      241 gatatgataa cacatcattg caagatatta tcaatgaaac aaaactttct aaaggtgcta
      301 tttatcatca tttcgattca aaggaagata ttttaaaagc aatttttcaa agaattggaa
      361 atgaaaatgc agtaatattt gctaaaatta gagataacga tagtttaaac ggtttagaaa
      421 agttaagaga aatatttaag acagcggtat tcaattctaa ccaaagcgtt ttattgacag
      481 tttctcctca actattaaac aatcctcgtt ttcttgctat gcaaatagaa caaatgtatg
      541 aaattgtagt acctgaattt gttgaacccg ttttagaaca aggtatcaag gataagtctt
      601 tggagattga aaattcacat gaaattgcag aagttatcat ggtattaagt aatgtatggc
      661 tcaacccatt agttgaaatg acggataaag agggtatgga aaaacgttgc aatacattca
      721 atgccctttt aaatggaata ggcatagaca cattattaga cgaagaaaca atttctgcat
      781 ttatacagtt ttgtaaataa ctgtatttgt tatccctata cgatagactg ctctataaaa
      841 gagcagttta tttaaaccat tatataaacc gacggtctgt ttgattaaat aaaaaggaga
      901 gattttatgc aagcagaaaa aaaacttttt aatcgtgatt ttatacttgt tgttatagga
      961 cagataattt ctttatttgg aaacgctatc ctacgatttg cattaccgta ctatttgtta
     1021 aaagaaactg gttcatcagc tttgtttggt attgctacag cctgctcttt tttacctatg
     1081 gttattttgt cgctggtagg tggtattatt gctgacagga caaataaaag aaacattatg
     1141 gtcatactag attttgtaac agcaatcata attttagtat tttatttgtc attgggaaaa
     1201 attcctatca tacctttgtt tattgttgct ttgatgttac tttatggtat ttctggtgca
     1261 tatcaaccag cggtacaagc aagtattcct ctattggtat catcagataa acttaccgtc
     1321 ggtaatgcta taataaatca agtaaatact ttagcaaact ttatcggacc agctataagc
     1381 ggagtagttt ttcaatttta tggtatcaat cccattttaa ttgttagtat tatatgtttt
     1441 actttttcag ccattatgga aatttttatc catattccac accaaaaaag acctcgtgaa
     1501 gtaggtgtaa ttgcagttgc taaaaacgat ttaaaagata gttatacctt tttgaaaaag
     1561 gagaaaccca tttttatatc cgtaatcttt ttggtttgca ttttcaattt ggttttaagt
     1621 gctgttttaa ttgttggtct gcctatctta atttctgaag ttttaaaaat gccagataca
     1681 ctatatggtt tttcacaatc agcattatca ttaggtggtt tatgtggtgg tattttaaca
     1741 gctcttgttg cttcaaagtt aaaactaaaa aacctttata ccttgttact tatttgttct
     1801 gtttctgttt tacttatggg aatttcgcta tttttagaat tgcctgcaat agtttcctac
     1861 tgggtagtta cagtgatgtg ctttgtggct atgggtgtat ctactatgtt tgttgttcaa
     1921 atttacactc ttgttcagac acaaacacca ccgcaattag taggaaagat aatggctacg
     1981 ctggtagcag ttgctatgtg cggtcaacct attggacaaa tggtttacgg tattttattc
     2041 gatgtattta tacaagaaac atgggttgtt atgtttgtag cttctattgc ttcaatcatg
     2101 atttcaatat attcaaaaag aatttttcaa aagttagaga tataatacaa ggggttaaat
     2161 agtatgttag gctaaaaaca atatataaaa gaaaatttga aatctgctaa aaggatagtg
     2221 ttataaaaga aagagtaata ttgcagtatt taaggctcgc acaaatatat gttttgtgtg
     2281 ggcttttttc ttaccatttt tctgtatttc taaagggtat aaacggtatt ccgtttatat
     2341 atttcagcat tagcagaaag ggggtgagat tatgaggaca tcttctttcg agcatatcgt
     2401 cagattacag ttcaattctt taatgctgat tgtcattaag aacaaagtga aaagtcgaaa
     2461 cagacagctt gcaagacatt ctaaacgtga agtattgttt tgtgaaatag ccgaaacgaa
     2521 acaagttgaa cgtggaacga ttgatacctg tttttatgat tgtgtatcat ttaaagtctt
     2581 gcactttaca atttatgtat ctgatgaaac acttggtaca gttttacata gactgtcaga
     2641 aaaacagcgt agtgcgattt tattacgtta ttttcaagga atgaacgaca gagaaatttc
     2701 agaactgtac catgtatcac gttctgctat ttgcagtaga agaactagag gactaaggaa
     2761 gttaaaaatg cttttgagcg aaaggaagta aagaaat
//
LOCUS       DAZKPE010000161         2787 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000161 DAZKPE010000000
VERSION     DAZKPE010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.167"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            81..698
                     /locus_tag="ACG930_002959"
     CDS             81..698
                     /locus_tag="ACG930_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0520056.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            698..1636
                     /locus_tag="ACG930_002960"
                     /pseudo
     CDS             698..1636
                     /locus_tag="ACG930_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(2329..>2787)
                     /locus_tag="ACG930_002961"
     CDS             complement(2329..>2787)
                     /locus_tag="ACG930_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HFQ0520057.1"
                     /translation="NKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWTESDKN
                     FISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNSSFLLP
                     IITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
BASE COUNT         1027 a          447 c          470 g          843 t
ORIGIN      
        1 tgataagcaa tttgaaattg aaaaagtaga tattgctgat tggttattgc aaccgagaga
       61 attttagagg ttggttgaaa atggctaaaa ttggttatgc acgtgtcagt agcaaagaac
      121 agaacttaga tcggcaatta caagcgttac agggcgtttc taaggtcttt tcagacaaat
      181 taagcggtca atcggtcgaa cgcccacaat tacaagctat gcttaactat attcgtgaag
      241 gggatattgt tattgttact gaattagatc gattaggacg aaataataaa gaattaacag
      301 aattgatgaa tcaaattcaa attaaggggg caaccctgga agtcttaaat ttaccctcaa
      361 tgaatggtat tgaagatgaa aatttaaggc gtttgattaa tagccttgtc attgaattgt
      421 acaagtatca agcagaatca gaacgaaaaa aaattaagga acgtcaggca caaggaatcg
      481 aaattgctaa gaaaaaaggc aaattcaaag gtcgtcagca taaatttaaa gaaaatgatc
      541 cacgtttaaa gcatgctttc gatttgtttt tgaatggttt atccgataaa gaagttgaag
      601 aacaaactgg aatcaatcgc cgaacgttta gaaggtatcg agcaagatat aacgtgacag
      661 tcgatcaaag aaaaaacaat gaaaagaggg atagttaatg agtacggtta ttttagctga
      721 aaaaccaagc caggcattag cctacgcaag tgctttaaaa caaagcacca aaaaagacgg
      781 ttattttgag atcaaagacc cactatttac agatgaaacg tttatcacct ttggttttgg
      841 gcatttagtg gaattagcag aaccaggtca ttatgacgaa aagtggcaaa attggaaact
      901 tgaatctttg ccgatttttc ctgatcgata cgattttgaa gttgcaaaag ataagggaaa
      961 gcagtttaaa attgttgcag aacttctcaa aaaggcaaat acaattattg ttgcaacaga
     1021 tagcgacaga gaaggtgaaa atatcgcctg gtcgattatc cataaagcaa atgccttttc
     1081 aaaagataaa acatttaaaa gactatggat caatagctta gaaaaagatg taatccgaag
     1141 cggttttcaa aatttgcaac ctggaatgaa ttactatccc ttttatcaag aagcgcaaac
     1201 acgccaaatt gccgattggt tgatcggcat gaacgcaagc cctttgtata cgttaaattt
     1261 acaacagaag ggcgtacaag gtacattttc actaggacgt gttcaaacgc ccaccttata
     1321 ccttattttt cagcgccagg aagccataga gaattttaaa aaagaacctt ttttcgaggt
     1381 ggaagctagt ataaaagtaa accaagggtc gtttaagggc gttctaagcc ccacacagcg
     1441 ttttaaaacc caagaggagc ttttagcttt tgtttcttct aaacaagcta aaataggcaa
     1501 tcaagagggg ataattgctg atgttcaaac caaagagaag aaaacgaata gtccgagttt
     1561 gttttcttta agtagtttgc aatcaaaagt caatcagctt tataaagcga cagcgagcca
     1621 aactttaaaa gctatttctt ttttaataac ttaaaaataa acttaatgta acagcaagca
     1681 cagtcaaggt atacaccttt gacaaaaaat agcacattct ctatcgaaaa tttttgctta
     1741 ttttttaaat tattttggga aattttccca atcccttttt ctaactcaaa aaatataatc
     1801 actcaaaatt taaaagggcg cacttataca tcattttaaa aaattgatgt aacgtgctaa
     1861 gttcaaaaca aagggcgcac ttatacacga ttttcaatct tgtatatttc taacgaaaag
     1921 cgtgcgccaa aaaaccccct tcgtcaattt tgacaggggg ctttttgatg taaaaatttc
     1981 tatcgaaatt taaaaattcg cttcactcat gttataaaga cttaaaataa aataactctt
     2041 taaaatcttt tgctagttgt tcttcaatat tttttattcg gtgcatcttc caagtaaagt
     2101 ataacacact agacttattt actacgtttc ataagtcatt aatgcgtgtg ctctgcgagg
     2161 ctagtttttg tgcaagcaca aaaaatggac tgaataaatc agtccataag ttcaaaacca
     2221 aattcaaaat caaaaccaca agcaaccaaa aaatgtggtt gttatacgtt cataaatttt
     2281 atgatcactt acgtgtataa aattaaattc actttcaaaa tctaaaaact aaatccaatc
     2341 atctacccta tgaattatat cttgaaattc attcataaat agtgaagcat ggtaaccatc
     2401 acatacagaa tgatgaagtt gcagagcaac tggtatataa attttattat tctcactata
     2461 aaatttacct atcgtaataa taggcaataa aaagctgcta ttgttaccaa tatttaaatt
     2521 aaatgaacta aaatcaatcc aaggaatcat tgaaatcggt atggtgtttt caggtatcgg
     2581 ttttttagga aacatttctt ctttatcttt atattcaagc aagtcatttt tataattatt
     2641 ataaaaagaa atgaagtttt tatcagattc agtccaaatg ttagtaaatt tttcagtttg
     2701 cttattaaaa actgtataca aaggatttaa cttatcccaa taacctaatt tattctcact
     2761 attaattcct gttctaaaca ctttatt
//
LOCUS       DAZKPE010000162         2682 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000162 DAZKPE010000000
VERSION     DAZKPE010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.168"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            522..668
                     /locus_tag="ACG930_002962"
                     /pseudo
     CDS             522..668
                     /locus_tag="ACG930_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            complement(756..1049)
                     /locus_tag="ACG930_002963"
     CDS             complement(756..1049)
                     /locus_tag="ACG930_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFQ0520058.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            1086..1271
                     /locus_tag="ACG930_002964"
     CDS             1086..1271
                     /locus_tag="ACG930_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520059.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            complement(1450..2628)
                     /locus_tag="ACG930_002965"
     CDS             complement(1450..2628)
                     /locus_tag="ACG930_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0520060.1"
                     /translation="MENMSRFKKHITATGKITWYFQAFRTTRRGFNSKREAQLAYLEM
                     EKQHRNKQKRIASNDKFNVVSQKWFEYYRSLNEQKRATYDKREEQVKILNRWIGDKKL
                     SSLSSEELQKFLFILKEKGIDGIDVGYAKNSLQSLVQVLNMIFKYCKKKNLINENPME
                     FVKMPKYQLTVEDLKESVNSLEDKFLTVDELRTFLNYGIIYEELPMSVLFHVLFYTGC
                     RVSEALALQPQDIDFERNEILFYKQTAVKGKSKDFRIETTKSVSSARRVPVTPLVMEK
                     LHELIDVLNKTKRNSNFVVDETYLFVYLDPGKRGVPYRREYVNDHVKRCVERCGINKN
                     FHTHLARHTMASLVAEYCSWDVLKDRLGHTDSTTSKIYRHLTSNERIKPLLAFDSLEN
                     "
BASE COUNT          848 a          475 c          361 g          998 t
ORIGIN      
        1 tggggctttt tttctctttt tattctaagg ttattttagt cttgtccttt aatacaaaga
       61 ttttattttt aaataaaaaa tactcttttt ttacgattat tgaaaaaaaa agataaaact
      121 tgattaattg aagtattgct taaatttgga agctatgagg gaagaataaa agagttagga
      181 cgggattatc tactattttt ctttgtttta aatatttgtt atctttgaac ataaaagaga
      241 aatgtgtcga ctgcagtgtt gtgtccctca tcacgaataa acggtgttca attagctgat
      301 cttgtattca cttaaaaaat ggtaaagtac gagttgctat tccccatttt caattttcta
      361 acgctcagga caaaatactg ttttcacaac ctcattggaa taaaagcata tatattgttt
      421 caagaacgaa atcttgttat ctttttaaag ggcatctgtc caaaatctaa ttttaggagg
      481 tacgttttgg tatttattcg tacaaataaa agagaattat ctttattcat gtaacgcatc
      541 caattgattt tttcatgtac gctcctggaa cgattttact gacgattgct tatttaactg
      601 cgaatcgctc attagctttt atcatagcta tccatatttt gaataacgtt cttggctttg
      661 tattatagat acagatgaca aaaaaagttc aagtatgcgg tgtagaacca atatcgcata
      721 cttgaacttt tttcaatgag tataaattaa aacttctaat tttcaattcc catcatctga
      781 tatgcccgac cgtctgaact tcttttgaaa aagccaaatg tgattagata acgtctttgt
      841 tcgacataat cgccactaga aaatacgttc agcagtatcg aattaacctc tgtttctgta
      901 taagtcactc catggtcaaa gcgtttcaag acttctttca ataggatgta tttctttttt
      961 gttgaacttg gtacttgttt tacttttcca tcattcatga atgtgtctaa aactttcatc
     1021 ttttcttgct ccgtataagt ataaaccatc ttctttctcc ttttgattct aagaatactc
     1081 catttatgtt agaatattct ggatttttta ttaaagcggt tactcttaag aaagatatta
     1141 tcatagtgct ctttttttta ctactactta taggtagatt tattctaatc cattattctc
     1201 ccctaccaat aattaaagaa aaaactggat cagggtgttc aaattacatg ctaagaaaaa
     1261 agaacccttg aataccaagg gttctttctc agtctgataa caatgattaa cgacggattt
     1321 ctttgatact tgtgaaaagt cattaaagta ttgatataaa agtttttctc tttttctgac
     1381 tacactttga ctaaagcata gtcacaacac ctattttaga ttctaaaata cctgcacttc
     1441 tgccaaaatc taattttcta atgaatcaaa agcaagcaaa ggctttattc tttcgtttga
     1501 tgttaaatgc cgatatattt ttgaagttgt actatctgta tgacctaaac gatcctttaa
     1561 aacatcccaa ctgcaatact cagctactaa actagccatc gtatgacgag ccagatgagt
     1621 atggaaattt ttgttgattc cacatctctc tacacagcgc ttaacgtggt catttacata
     1681 ttcacgacga taaggaactc cacgcttacc aggatcaaga taaacaaata aataagtctc
     1741 gtctacaaca aaattgctat ttctttttgt tttatttaat acatcaatta attcgtgcaa
     1801 tttctccatt actaacggtg tgacaggtac tcttctagca gaactaacag attttgtagt
     1861 ttcaattcga aaatctttgc tttttccttt tactgccgtc tgcttataaa ataagatttc
     1921 atttcgttca aaatctatat cttgaggttg taaagcaagt gcttcactca cacgacaccc
     1981 agtataaaac aaaacatgaa aaagaacaga catgggtaat tcttcataaa tgatcccata
     2041 atttaaaaaa gttcgcaatt catctactgt taaaaactta tcttctaaac tattaacaga
     2101 ctcttttaaa tcttcaactg ttaactgata cttaggcatt tttacaaact ccattggatt
     2161 ttcatttatc aaattctttt tcttacaata tttaaaaatc atatttagaa cttgaacaag
     2221 agattgtaaa ctatttttag cataaccaac atcaatgccg tcaattcctt tttcttttaa
     2281 aataaaaagg aatttttgta gttcttctga agataaactg cttaattttt tatcaccaat
     2341 ccatcgatta agtattttta cctgttcttc tcgcttatca tatgttgccc tcttttgttc
     2401 gtttagtgat cgataatatt caaaccactt ttgactaacc acattgaatt tatcattact
     2461 agcaattctt ttttgcttat ttctgtgttg tttttccatt tcaagataag ctagctgagc
     2521 ctcacgctta gaattaaaac ctcgtctcgt agttcgaaaa gcctgaaagt accaagtaat
     2581 ttttcctgtt gcagtaatat gttttttaaa acgactcata ttttccattt gtttttaccc
     2641 ccaattatga aggaacccaa caatcggaaa ctcttgaaaa tc
//
LOCUS       DAZKPE010000163         2660 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000163 DAZKPE010000000
VERSION     DAZKPE010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.169"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            25..348
                     /locus_tag="ACG930_002966"
     CDS             25..348
                     /locus_tag="ACG930_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520061.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            512..766
                     /locus_tag="ACG930_002967"
     CDS             512..766
                     /locus_tag="ACG930_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520062.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            836..1081
                     /locus_tag="ACG930_002968"
     CDS             836..1081
                     /locus_tag="ACG930_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0520063.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            1157..1522
                     /locus_tag="ACG930_002969"
     CDS             1157..1522
                     /locus_tag="ACG930_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFQ0520064.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1583..2146)
                     /locus_tag="ACG930_002970"
     CDS             complement(1583..2146)
                     /locus_tag="ACG930_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520065.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT          778 a          473 c          420 g          989 t
ORIGIN      
        1 atgttattct tttatttatt ctcaatgtta ggagtgatta ttttgccatt tattgcgatt
       61 ttattcgatt tagttgcggc agcagcttat tttctccaat taaattatca aacctcagga
      121 attctgttta ttggaatgat ttttcaaggt gtgattaccc ttttgcttct tgtcatgatg
      181 ctcagctata aaggaaaaag atatgcccgt attcaaacaa aagtatttgt taaatatgtt
      241 tccattcgct atgggatcat cattctttcc tttttagtga atgcgatcgt cctcttttta
      301 tatgtattga attacttaga tatcaatcca ttgatttttt ctcgatagat aagacacatt
      361 cagcggaaca gttcctgctt atcagcagaa aactgttctg ctttttcatt tttcattgat
      421 ctattcttct tttattttcc tagcatttca tttgtgatgt atgcaataac atgttatctt
      481 ttattatatg aatcgttgag gagtccgtta catgattacg ttggtgagag ttttgttttg
      541 ggtgcctgcg gtcgcactgg tcgcaagtat tgtttatctt atgaattgga acaaagaacg
      601 gttttattta gctattttga ctcttccggc tatctacttt atgtggaaag tttttaatta
      661 caactacttt gaacccgata gtgtttttat agaagaatta tcaggactgg ttttgtcttt
      721 attgatcgtc attctttatt tgatacgttt aaataaaaaa cattgagtac tattgattgc
      781 atgtgtagct ttctatagtc attataacta ttctactata atgaaaggtg attaaatgag
      841 tatcgaagaa gctattttac tggatacttt acgttgtcgt ctgaatttct taagaactgg
      901 ccgatcttta tctcaagtag ctgtttctag cgcgttaagt attcctttat tcaaatatcg
      961 taagtacgaa gaaggagaag aaattccaag catcattgaa ttaatctata tcgctgactt
     1021 ttacgatatt tccgttgatt acctaattgg tcgctcagaa acagcaagca aactgaagtg
     1081 attttttcca gccttggtgc tggttttttc atttaacgtc taaggttaac aatctatata
     1141 taaaggagac atttctatgc gattatggca tgaaaaattg atttcaaagc ttcctcgtca
     1201 acagctttta ggacaacatc gggaatgctg tgcattaaga ggaaatggct ggggaaagaa
     1261 acatgctact gtggattatg tttttcacta ttctccttat agattattcc aatatcatca
     1321 gcttgtcatg gatgaaatgg aaaaacgtgg ttacagccca gcaccagagt ggaaaaatcc
     1381 tatgtatcgt ggcaaatcat gcgaagcatt ttttgattta cctactgtag agcgcaacgt
     1441 gccgatttat ccggaacacg atgaagttta tctagcagaa tgtttagcaa atttggagca
     1501 aaaaggaatt tatcttacct aatataacta gaaaagcctt ctatctcctc ttacttcatt
     1561 aaaaagcttt aaccatctta gatcaagcta aaatgtcgta agttttaggg ttatcttcat
     1621 cctcacgtgc aaaactaaaa gcgtactcta gttttggttc atcgccaact tccctagaca
     1681 taaatgaaca tctcctgacg tggtttaaaa gtaccgcatc ttcgacgtct gtatacgatg
     1741 cacagcacag attgcttctt ttgatctttc ttttgatttt tctgttgctt cttctacacc
     1801 ttcttcgatt actacatcga tgcttacaat tgcttctgcc taatattccc atgcatcgtc
     1861 gatttaagcc tctgtagtca ctgtgatcgt ttccacattt taactcctct gtcgtggctt
     1921 cagttgattt tgtgatcagt tcagttgcta agccagagtc agaacaacct gccattgcta
     1981 gcgttaatat tgatagtaaa aatagttttt ttatcataag gttccccccc tgaaaataga
     2041 ctaaaataat aacgctttct ttttttgttt tcagacgaaa attaataatt tctaaatatt
     2101 ctttaaaaaa gcttataact attatgcctt ttttaatata taacacagtt atttttaaaa
     2161 ataagaatgc taaatcactc tacaataacg gcgaaagcac aaaaaataaa aaaattatta
     2221 cgttattaaa aaaacagatg aaagatcagg ttttattaga tctcattctt tcatcacttg
     2281 aagggattta atgaactact ttttcctctt tgtcgttttt atatattcgt attccttcaa
     2341 acagtaggat agcctctttc aatgcttgat atttgaactg tccgttactt aaaaatttag
     2401 atgtgccgcc ctcttcctag aacatattct tttttacttt ttcattaatt gacagaccaa
     2461 tcgaacgaaa ctgtaaattt cgataggata atgattggtc aaactcattc attttcaaga
     2521 catctcgatt catattcaag ataggaatct ttttatcaac atcactttat tcgtattttc
     2581 ctctaccata aaagcttcac gctccacaaa attgttttat acactactat tcagcccatt
     2641 caacgaccaa tgaatttttt
//
LOCUS       DAZKPE010000164         2596 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000164 DAZKPE010000000
VERSION     DAZKPE010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.170"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            80..1204
                     /locus_tag="ACG930_002971"
                     /pseudo
     CDS             80..1204
                     /locus_tag="ACG930_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1624..2268
                     /locus_tag="ACG930_002972"
     CDS             1624..2268
                     /locus_tag="ACG930_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0520066.1"
                     /translation="MYKTANELFNRLKSEKKELILNYILEEFGRVGYESASVRKIADK
                     ADLSAGSLYQYFNNKEGMLRVAIEHVFVILDEYINNINNAPLKLENRLEVMFETILEL
                     GRKHPELIVFYNKIPGDEQMTSEWVKQFYNNTSFFKVYWHTVNELQDEKEISDKIDPV
                     VYTFIIDTMMLSGELLQNTQYQEIKAKIFLEDSIKSSLILKENVIETLTVLARG"
     gene            2275..>2596
                     /locus_tag="ACG930_002973"
     CDS             2275..>2596
                     /locus_tag="ACG930_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0520067.1"
                     /translation="MTISNKNSMREEIIIIAIKHFSKFGYEKTRLLDIANEAKTSTTT
                     VYSFFKTKHDLYEAAVEYDLNIINLELEKIVKESSTLDEYIINIVERVRLNSEKKQLF
                     LNFFM"
BASE COUNT          983 a          358 c          491 g          764 t
ORIGIN      
        1 tgtttggata ggctacaatt aactagacag aaaaattaag gtgtgtaaaa tataagaaaa
       61 cacactggag gaattgttaa tgtcagaaag aaaaccacgt cgaacgttta ctaaagagtt
      121 taaaaatcaa atggttcagt tatatgcgtc agggaaaaag agaaccgata ttatcagaga
      181 gtatgattta accccgtcta cttttgataa atgggtgaaa caagcaaata cctctggctc
      241 atttaaagaa aaagataact taacacctga acaaaaagag ttaattcaat tgcgaaagca
      301 aaataaacaa ctcttgatag aaaatgatat tttaaagcaa gcggcgctga tattcggacg
      361 aaaagacaag taattgatgc aaataagcac aaatactcga tatcagccat gtgtaaagta
      421 ctgggtattg caagagccac ctattattat cgagaaaaag aaacgactca aggcgcagta
      481 gaagcaaaat tagaagaagc ggtggaagaa gtttttcaac aaaatagacg agcatatggt
      541 tcacgcagaa tcaagaaacg ccttgataag aaaaatctca ttttgagtcg tcgaaaaatt
      601 cgtcgcatca tgaaaagacg aggattgaaa tccagttaca cgaagcccaa atatcgcgta
      661 cattcgtgcc aaagcaatca aaagaaaatt gcgaatcact tagatcgaaa gtttactcaa
      721 acaaaagcat tgtcagcggt tgtcacggat ttaacttatg ttcgggtcgg gacaaattgg
      781 gcttatattt gtttgatgat tgatttattc aatcgtgaaa ttattggcca ttcttgcgga
      841 aataaaaaag atgcgcagct tgtaaaaagg gccattcaaa gcattcctta ctcacttcaa
      901 gaaatcgaac tcttccatac ggatcgtgga aaagaatttg ataatgaatt gattgatctt
      961 atcttagaaa catttggcat tcaacgctcc ttgagtaagc ctggatgtcc atatgataat
     1021 gccgtttcag aagcgactta caaagctttt aagacggaat ttgtgagtca atatcaattt
     1081 gaaacgatgg cacacttaga attagaatgt tttgattatg tcaattggtg gaatcatcat
     1141 cggatccata gttctcttgg ttataaaaca ccaattgagg tacgctatgc ggaggttggc
     1201 gtagcgaacc cttgataatg agcaagaatc ggttaccttc tgttcgagcg gcttatttta
     1261 ttcaaagtga gcacgccgct aagaaaaccg atttgaggag gctcgttgtc aagggcaact
     1321 ggatatggtg tcataaacag accttataat ttttgtctag aaaagtgttg ccattccata
     1381 catctagagt tattttatat ccccttgaaa gtcaggagtc ttgtaaagaa taatgaaaat
     1441 attaagactt ctgaaattaa gtcgggtcac acttctgtaa atagttcaga cgaaattatt
     1501 agtagtagaa aagtaaatgg ttggaaaatg attcaattag gagaagcttt aaaaaatgag
     1561 cggtcgtttt tataaggtta atatggtata cttagttata atatcttttt tgaggagata
     1621 gctatgtata aaacagcaaa tgaattattt aatcgattaa aatcagaaaa aaaagaactc
     1681 attttaaact atatcttaga agaatttgga agagttggtt atgaatctgc ttcagttcgt
     1741 aagattgctg ataaggcaga tttaagtgca ggatcattat atcagtactt taacaataaa
     1801 gaaggaatgc taagagtagc aatagaacac gtttttgtta ttttagatga atatattaat
     1861 aatataaaca atgctccttt aaaattagaa aatcgtttag aagtaatgtt cgaaacaatc
     1921 ttagaattag gaagaaaaca tcctgaattg attgtttttt ataataaaat tcctggtgac
     1981 gaacaaatga caagcgagtg ggttaaacaa ttttacaata acactagttt tttcaaagta
     2041 tattggcata ccgtaaatga attacaagat gaaaaagaaa taagtgataa aattgatcca
     2101 gttgtctaca cgttcattat tgatacgatg atgttatccg gagaattact tcaaaatacg
     2161 caatatcaag aaataaaagc caaaattttt ctagaagact caataaaaag ttcattaata
     2221 ttaaaagaaa atgttatcga gacgctaact gtacttgcaa gggggtaaga gtctatgaca
     2281 ataagtaata agaatagcat gcgagaagaa attataatta ttgctataaa gcatttttct
     2341 aaatttggtt atgagaaaac aagactttta gatattgcta atgaagctaa aactagtact
     2401 actactgtat atagtttttt taaaacaaaa catgatctgt atgaagctgc agtggagtat
     2461 gatttaaata taataaacct tgaacttgaa aaaattgtta aggaaagttc tacactcgat
     2521 gaatatatta taaatatagt tgaaagagta cgattaaatt ctgaaaagaa acaattgttt
     2581 ttgaattttt ttatgc
//
LOCUS       DAZKPE010000165         2545 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000165 DAZKPE010000000
VERSION     DAZKPE010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.171"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            289..696
                     /locus_tag="ACG930_002974"
     CDS             289..696
                     /locus_tag="ACG930_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520068.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            710..1111
                     /locus_tag="ACG930_002975"
     CDS             710..1111
                     /locus_tag="ACG930_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520069.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1113..1484
                     /locus_tag="ACG930_002976"
     CDS             1113..1484
                     /locus_tag="ACG930_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520070.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1520..1822)
                     /locus_tag="ACG930_002977"
     CDS             complement(1520..1822)
                     /locus_tag="ACG930_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0520071.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2080..2193)
                     /locus_tag="ACG930_002978"
                     /pseudo
     CDS             complement(2080..2193)
                     /locus_tag="ACG930_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          937 a          352 c          433 g          823 t
ORIGIN      
        1 tttgagggga agtacatata gttgttgata tagttgctaa tattgttagc taatttgtta
       61 gtaaaactgt atacgaattt agatagtaaa aaaacagttt gttccttata tagaggcact
      121 tttactactg attaaatgtc agatatgctt acaaatatac ttataaatat gcttacaaaa
      181 ttagctaata tttccgttga caaagctttg ttactattgt taaactaaat tgactagcaa
      241 aagtgaaaca taaatttatt aaataaatgt aaaaattagg agaaatcaat gtcttataga
      301 gtacaattaa taatttcaga agatgtagaa agtcagcaat ttggcactaa tgttattaat
      361 aaagtaatta atccagctct ttctattaat gcgcctttaa ttcctactgc tttatcattt
      421 tctgtaacag ctgtggtgtc tgagatagag gatacagaaa agataaaaat agtagaaatt
      481 gaagttttaa acaagaatga aaaacaaatt ttttctacgg gtgaagtatc ggtaagcttg
      541 cctcctcaag ttaacgatat aaactttaat ataaacgcca gaaatgtctt ggttgaagaa
      601 gcaggagagc attatgctgt tgttaaattt aatggaactg agattggaag gcaaatcttt
      661 gatatcaagg tcaacaaacc agtggaaaaa aattaaggag acgatacgga tgcttgatat
      721 agtaccatca aatacacatc ggagtggtag cttaataaat tttgctgcga tttttgcttg
      781 cgcatcggta attctagcat ctccagttgt tgtggatgca agttctactc cgaaaactaa
      841 aaatgataat caacttgtaa ttactacaaa aaatgagatt aacacaattt caagtaatga
      901 tggcaaaatt tttgatgtga taaatacggt tttaaaaaga aaagctgaaa tcaatataaa
      961 atatgatgaa gatttaaact tgtatttctt tgttatcaaa acaacatctg aattgttttc
     1021 ctcagattac gatgttttgg atactctcga taatgtatta tctgactata aatatatggg
     1081 gaaatctgta gtagcaactt tgggggaata aaatgtttga ctttaatgaa tatttatcta
     1141 tttccaaaca aattgaatca gatgataaat ataattctaa agaatcttat agaagaactg
     1201 ctgtttcaag agcatactac agtgctttta aaaaatctga tgagtatttg aaagaaaatt
     1261 atgatattat ttataatgga agtagcggaa aaggaagcca ccaaaccgtt tggaatttgt
     1321 tttcaacagt taaggaattg aataccttag gaatacataa tagtgggtat agaatgttag
     1381 agaaaagaaa atgtgctgac tatattccta atgaaaccat tacgaaaaca gatatggcgc
     1441 tgatgaatcg agaagcagaa aaaataataa acaaactcac ctaatgaatt tcaagcgagt
     1501 ttgtttgtta tttttttatt taatctttgt atctttctgg atcaacgaaa gtatacttta
     1561 tatagtcata acgccgatga tcgctacgtg cgtccggcac gtcagtcacg atatcaaaca
     1621 aaaagtatac acccttcttc attctagttt tcgcagcagg aattttgaaa tagttcttat
     1681 tagaatagta gagattgatt aataagctat cttcgattgc taaaaagaaa acttctgaat
     1741 tccatacttt ataaaaatct ttgataaatc tattcgaagg gtcaaattta aaccataatt
     1801 gtgtttttcc ttccatcagc ataaaagttc acctcaaaaa gagtatacga acgaatgttc
     1861 tttttgtgaa ggcggaattt aatatactga ataatagaaa acaagtactt gtgccaaatt
     1921 atgtgccaaa aaaattcgaa ttcaacaaaa tgtaaacaaa tagaaaacct tctatattaa
     1981 gatttcctgc aataacaaac acaacagaag acgtgtaata gttagtcagg aacgtacaaa
     2041 taacccctgt atcctttgcg gtacaggggg ttattttgta taagtagaca ttgtagtttc
     2101 taaactgcta tgtcctaaac gtttcgatac gctaagtata tttactcctt gataaagtaa
     2161 aatagatgca tgcgtatgtc ttagtccatc aataaacagt cgaagagaaa atagggaaaa
     2221 attgattact aaagaaaaac ttactaggtc gacggtgtag ttgattttca tacttcaata
     2281 gattcgaatt aaacgatttc gattggctta taccagtcct atccaacgaa agatatatcg
     2341 ttcttaactc tagcggtata acttgaagct ttacgtaaag ccaatgggaa tgaactggag
     2401 atgacttttt attattttta gtaatagctg atgggttaat acttacaact ttccttttca
     2461 aagtaccata taaaaaaacg gtggggttgt ttagcgaaat aaaggatcta agccaatagc
     2521 ttagatcctt tattctatgc tttat
//
LOCUS       DAZKPE010000166         2520 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000166 DAZKPE010000000
VERSION     DAZKPE010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.172"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..569
                     /locus_tag="ACG930_002979"
     CDS             <1..569
                     /locus_tag="ACG930_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0520072.1"
                     /translation="HLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSD
                     YDLIIIDTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGL
                     DMIGFVPYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKG
                     YDKKVLSMYENVFFEMLERIIQLENEKE"
     gene            661..876
                     /locus_tag="ACG930_002980"
     CDS             661..876
                     /locus_tag="ACG930_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFQ0520073.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            894..1166
                     /locus_tag="ACG930_002981"
     CDS             894..1166
                     /locus_tag="ACG930_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0520074.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1168..2031
                     /locus_tag="ACG930_002982"
     CDS             1168..2031
                     /locus_tag="ACG930_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFQ0520075.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT          999 a          413 c          442 g          666 t
ORIGIN      
        1 ttcatttgac tgataattta gacttgatcc ctggcacgtt tgatttgatg ttactgccaa
       61 aattaactcg ctcatggact tttgaaaatg aaagtagatt gcttgctact cttttagcac
      121 ctttaaaaag tgactatgat ctcattatta ttgatactgt accaacgcca agcgtttata
      181 caaataatgc aatcgtggcg agtgattacg ttatgatccc tttacaagca gaagaagaaa
      241 gtacaaacaa cattcaaaac tatatttcct atttgattga tttacaagaa caatttaacc
      301 ctggactaga tatgatcggt tttgttcctt atttagttga tacggacagc gcaacgataa
      361 aatcaaacct ggaagaactg tacaagcaac ataaagaaga taacttggtt ttccaaaata
      421 ttatcaagcg aagtaataaa gtaagtacct ggtctaaaaa tggaattaca gaacacaaag
      481 gctatgacaa aaaagtttta tccatgtatg agaacgtatt ttttgaaatg cttgagcgaa
      541 ttattcaatt agaaaacgaa aaagaataga atcacaaatc acaagtgatt aatcacaaat
      601 cacttgtgat ttgtgattgt tgatgataaa ataagaataa gaagaaatag aaagaagtga
      661 gtgattgtgg gaaatttagg cgcacaaaaa gcaaaacgaa atgatacacc aatcagtgca
      721 aaaaaagata taatgggaga taagacggtt cgtgttcgtg ctgacttaca ccatattata
      781 aaaattgaaa cagcaaaaaa tggcggaaac gtaaaagaag ttatggatca agccttagaa
      841 gaatatatac ggaaatattt acctgataaa ctttaaaaag gagtgaaaat gaaatggcag
      901 ttacgtatga aaaaacattt gaaatagaga tcattaacga attatcggca agcgtttata
      961 atcgagtatt aaactatgtt ttgaaccatg aactagatac taaaaatact cgtttactag
     1021 aagtgaatct tttaaatcaa ttagaagtgg cacaagaagt tgatttattt caacaaccat
     1081 ttgaagaatt acaagctatt catgagtatt ggcggtcaat gaatcaatat tcaaaacaaa
     1141 ttttgacaaa agagaaagtg gcttaacatg gcgaatatta ctgacttcac cgaaaagcaa
     1201 tttgaagatc gtttagaaaa gaatgttgaa cgactaacta aaaatagact agcggttgaa
     1261 tcgccaaccg cttttttact tggtgggcaa ccaggatcag gtaaaactag tttgcgatcg
     1321 gcaatttccg aagagacaca aggaaatgtt gttatcattg ataatgatac gttcaaacaa
     1381 cagcacccta attttgatga actagtgaaa ctttatgaaa aagacgtagt aaaatacgtt
     1441 accccttatt ctaatcgcat gacagaagcg atcataagcc gtttgagaga taaagggtat
     1501 aatttagtga ttgaaggtac aggacgaaca acagacgttc ctattcaaac cgcaacaatg
     1561 cttcaagcca aagattatga aacaaaaatg tatgtcatgg cagtacctaa aatcaactca
     1621 tatttaggaa caattgaacg gtatgaaact atgtatgcag atgatccaat gacagccagg
     1681 gcaacaccaa aacaagcgca tgatattgtt gtcaaaaact taccgaccaa tttagaaacc
     1741 cttcataaaa cgggcttatt tagcgatata aggctttaca atagagaagg agtgaaactc
     1801 tattcaagct tagaaacgcc ttccattagt ccgaaagaga ccttagaaag agaattaaat
     1861 cgtaaagtat cagggaaaga aattcaaccg actttggaga gaatagagca aaaaatggtt
     1921 caaaatcaac accaagaaac ccctgaattt aaagcaattc aacaaaaaat ggaaagcttg
     1981 cagccaccta caccaccaat acccaaaaca cctaaacttc cagggattta aaccttaaaa
     2041 aagtaaaaga gtagttacca aaaaacggta actactcttt ttttataaaa acatttcctc
     2101 attttttaaa agctgatcga gaaataaagc acacaactgt attctttctt ttttcagttg
     2161 gtacattttg cagtctgtaa cgtgccattt actgtttgtt accttaacat atccagtcga
     2221 aaacacaagg gtatataaac gagcaagctc gcccttgtgt tttctttgtg tctatgttgc
     2281 gttctcgtca cagcaaacga cacgaacaca ctggcgaaaa tgaaccaaca aaacgaaaaa
     2341 agaaaggagc gtacactgta atttatttct agcttttaaa acatgaggaa aacagcttca
     2401 cttcctcaaa cgcctaacaa aaatggttgt caaaaaacta aaaatcaaaa aaagaaaaga
     2461 ggaaaagaaa atggaaaaaa caaaaaaatt acaattagaa gattttacag aaaatgggtg
//
LOCUS       DAZKPE010000167         2426 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000167 DAZKPE010000000
VERSION     DAZKPE010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.174"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(41..979)
                     /locus_tag="ACG930_002983"
     CDS             complement(41..979)
                     /locus_tag="ACG930_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0520076.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            1470..2426
                     /locus_tag="ACG930_002984"
                     /pseudo
     CDS             1470..2426
                     /locus_tag="ACG930_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT          838 a          422 c          390 g          776 t
ORIGIN      
        1 attatactga attagcaatt tttatcaaat aaaacttatt ttacttccaa aacctaaatt
       61 cacgttgcca aaaatcaatc tgcttttgca attgtttttc gttcgctttt aaagtcgatt
      121 tcattaattc cgttaaatca attggagata tttctctaat caatttttta aatttagtct
      181 tagtattctt acttagcttt ccccacatac tttcttcatg caacaaagta taaaccatag
      241 cttgctcatt aattttttct aaagtagccc acgcaggttt caagatgtgt aaatcattaa
      301 aacaatcatt ccagtaatca accatatctc tttttaattc aacttctaca cgccataaat
      361 gttcagacac aacttcaaca tctgcgttat ctttacgttc ttgtttttta ttataaattc
      421 taataaatct atcactatca cggacaccaa aatattttgt ttctggcttg ccattacgac
      481 cataaaaaac agttttctta actgctttat cagtcattgc atagtaatcg ctcaaatcat
      541 cttcaaaatc aaaagctaag tctaatcttg taaaaccgtc atcttccatg tagtcgataa
      601 tattttgttt taaccaaatc atttcttcat gtgtgagttt attgggatta aattcaacac
      661 gcatattacg tctatcccaa gtatctgctt ttactttgtc atattcgata taaacttttt
      721 cttgaagtgc cttagcttta aactttgttt gaagtatatc ccaaagtcgt atttgtggct
      781 ctacactcat aaagtcagat agctttttag cattagtttt gttcaaattt ccaacgattg
      841 tcatggcatc aaaacttaat gcgggttgag attttcccaa agtttgacca cttaaccggc
      901 tattacttaa ccggctatta gagacggccg gtttttttag tgagatttct gcagctaatt
      961 tttcatcaat tttcttcatt ttttatcgct cctaaaataa tttttggaac gaaaaaagga
     1021 cgagtggaat cgcaaaataa atttcgcctg tatccattcg tccattttgt tttgtattca
     1081 aaatcaaaaa ttgatatact aatcatcgaa tgaataacaa gtgtggtttg ttattccggg
     1141 cgagaacgtt ggtagcgttg ctcgtctttt tttatgtctt tttttcgtta aaactatttt
     1201 aaaactaaat atatcttaaa gcaaataaat tcaaggggct aaaagcgccc cttaaaaacc
     1261 ccttgcctct gaaaagtttt gtgtttcctt tccgtcggtt tcaaaagcta atttactcaa
     1321 aaaaatagat caagggtaaa tgcactcact gcgttcgccc ttgagctatt ttatttcgca
     1381 aattttaacg catttgccga cgaaaagata aaacacataa aaatatacgc agatatattt
     1441 aaaacgtctt agaacgcaaa attttacgtt taaaagctat gcaaggactg tatgaagcaa
     1501 aattattgag ttatccaaga acagatacac catttattac agagaacgaa tttgcttatt
     1561 taaaagcgaa ttttggcaaa tatagcggtt ttttaggact tgatcttgaa atggttcaaa
     1621 cagagcctag aaagcgttat gtggacggta gtaaggtaca ggaacaccac gccattatcc
     1681 caacaaaaca agtacctacc gaatctgcat tagcgaaaat ggacgattta caacgaaaaa
     1741 tttatgcttt agtcgttaaa acgaccgttg ccatgttttt acctgattac ttgtatgaag
     1801 aaaccaagat acaaacgaaa gtagctgatt tgctgtttca atcgatcgga aagacaccaa
     1861 agcaagaagg gtggaaaatt cttttcaaac aacaaaccaa agaagaaaaa gaggacgttc
     1921 aaacgttacc actcgttatc attggcgaac gtgccgaagt tggtgttaag agtgttgaaa
     1981 aagaaacgca accgccaaaa gcttttacag agggtacatt attaactgct atgaaaacgg
     2041 cgaataaaac ggttgatgat gaagaagcaa tcaagatttt acaagaagtt gaggggattg
     2101 gaacagaagc gacaagagca agtattattg aagcgttaaa acaaaaagaa tatatccaag
     2161 tgattaagaa taagcttgtt gtaactgaaa aaggaaaatt attgtgccag gcagttgaaa
     2221 gtcagcacct tttaacgagt gctgaaatga cggctaaatg ggaaacgtat ttaaaaaaaa
     2281 tcggtaaaag agaaggcaat caagagaact ttattacgaa tatcaaaaaa ttcattgttc
     2341 atttactgga agctgtacct aacgatatag aaaaactaaa tttttctgat taccaggaac
     2401 agaaagaaaa agaagcagaa aaaagt
//
LOCUS       DAZKPE010000168         2416 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000168 DAZKPE010000000
VERSION     DAZKPE010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.175"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..1147
                     /locus_tag="ACG930_002985"
     CDS             2..1147
                     /locus_tag="ACG930_002985"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFQ0520077.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1318..1776
                     /locus_tag="ACG930_002986"
     CDS             1318..1776
                     /locus_tag="ACG930_002986"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFQ0520078.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1935..2405
                     /locus_tag="ACG930_002987"
     CDS             1935..2405
                     /locus_tag="ACG930_002987"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFQ0520079.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          807 a          454 c          455 g          700 t
ORIGIN      
        1 catgcacatt caaacaaaat tgatccacgg aggcatcagt gaagatccca caacaggagc
       61 tgtcagtgta cctatttatc aaacatccac ttatcggcaa gatggcgtcg gccagcctaa
      121 acaatatgaa tattcaagat ctggtaatcc tactcgtttt gcattggaag aactgattgc
      181 tgatttggaa ggcggtgttc gaggattcgc tttttcttct ggtctttctg ggattcatgc
      241 cgttttttct ctttttcaag ctggcgatca tatcttatta ggagatgatg tctatggagg
      301 aacattccgt ctatttgaca aagttcttac taaaaatggt ctcgagtaca cgatcataga
      361 tacgagtaat cttgataaaa tagaacaatc catcaaaccc aatacaaaag cactttatct
      421 tgaaacacct agcaatccgc ttctaaagat tactgattta gaaaaaagtg ccactctggc
      481 tcatcaacat ggattgatag ttattgctga caatacattt gctactcctt attttcaaag
      541 acctttagat ctcggttctg atatcgttgt ccatagcggt accaaatatc taggcggaca
      601 cagcgatgta gtagctggtt tagtgacttc taaccataaa gatctagccg atcagatcgg
      661 attttaccaa aatgctatcg gagccgtact tggtccccaa gatagctggt tacttcagcg
      721 cggaatcaag acactaagtg ttcgtatgga ggaacatcaa aaaaatgctt ttgtggtagc
      781 tgattttcta ttttctcatc cagcagtaga aaaggtctac tatccaggat tacccgatca
      841 tgaactccat ggagttgcta agcagcagat gagcggcttt agcggaatga tttcttttac
      901 tttaaaaaat gaagaatctg ctattccatt tgttgaatca ctccaactat ttactttagc
      961 agaaagttta ggtggcgtag aaagtttagt ggaaattcct tctgtcatga ctcatgcgtc
     1021 tattccaaaa gaaaaacgag aagaggctgg cataaaggac ggcttgatcc gtctttctgt
     1081 aggaattgag tatggtcagg atctcataaa cgatttagct caggcatttg acagaatcaa
     1141 gaactagaag tcccaataaa cgacttagca gaaaaatcta aaaaatattt cagattgcta
     1201 caccttggaa acgataagtg ttagaatcaa gtagaaagac gtttttgtaa atttcactaa
     1261 ataattcttt agtgaaaagc atcaaaacga atgaacaaac agataggagt cttacaaatg
     1321 agaatgaatg tcgaaagttt taatcttgac catacaaaag tcaaagcacc ttatgtacgt
     1381 gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca ttaaatacga cgtccgcttt
     1441 aaacaaccaa ataaagaaca catggacatg ccaagtctac attcacttga gcacttgact
     1501 gccgaactaa tccgcaatca cgcagattac atcgtagact ggtctccaat gggatgccaa
     1561 acaggctttt acttgactgt attgaatcat gaaagctacg aagacatttt agatgttctt
     1621 gaagcaacaa tgaaagatgt tcttgaagct actgaagtac ctgcaagcaa tgaaacacaa
     1681 tgtggctggg ctgccagcca tacactagaa ggtgcacaag ctttggctcg tgaattttta
     1741 gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc taaaagaacg taaagatgag
     1801 aagcaatata gctatcttat cttcgtattt tattaaatat ttattgtctg aaaagagttc
     1861 taaacgggaa aacaaatagc tagttttcag tttagcgctc tttttattat ataaaataga
     1921 aaggagaaaa ctttatgtct atttataatt ttgaaactac tttagaagac ggcactgtct
     1981 attcattgaa aaaatatgca ggcaaaccga taatcattgt taacactgca acaaaatgcg
     2041 gtctagcacc tcaatttaaa caattagaag aactttacca agcttatcag acacaaggtc
     2101 tggttatctt aggctttcct tccaatcaat ttaaacaaga gctagattca gcgactgaag
     2161 cagcagaagc ttgtaaaacc acttatggcg ttaccttccc tatgcatcaa ttgattgacg
     2221 taaatggaga aaatacagat cctcttttta cttatcttaa aaatgaagct cctggtactg
     2281 tcactaaagc aataaaatgg aattttacta aatttttgat tgatagaaat ggcaaagtaa
     2341 tcgaacgatt tgcaccacaa acttctccat tgaaaatgac cgctgcaatt gaatccgttc
     2401 tttaacttaa taaaaa
//
LOCUS       DAZKPE010000169         2398 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000169 DAZKPE010000000
VERSION     DAZKPE010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.176"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            207..2069
                     /locus_tag="ACG930_002988"
     CDS             207..2069
                     /locus_tag="ACG930_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFQ0520080.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="ACG930_002989"
     CDS             2069..>2398
                     /locus_tag="ACG930_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFQ0520081.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAZKPE010000170         2386 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000170 DAZKPE010000000
VERSION     DAZKPE010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.177"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..437)
                     /locus_tag="ACG930_002990"
     CDS             complement(<1..437)
                     /locus_tag="ACG930_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0520082.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAVRIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVY"
     gene            751..1173
                     /locus_tag="ACG930_002991"
     CDS             751..1173
                     /locus_tag="ACG930_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520083.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1183..1386
                     /locus_tag="ACG930_002992"
     CDS             1183..1386
                     /locus_tag="ACG930_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520084.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1597..2181
                     /locus_tag="ACG930_002993"
     CDS             1597..2181
                     /locus_tag="ACG930_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0520085.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          795 a          363 c          432 g          796 t
ORIGIN      
        1 ttataaactc catttgcttt cgcaatttta atgccttgcg cctggcgtcg tttagattcg
       61 gtacgctctt gttcagcgat catggccaaa atttggatga tcagatcctt aatgaattta
      121 tccaggagag ggttgccaat tgcttcagcc atgatcggta gactggtgat gattagctgt
      181 acgtttttct tctttaggta attgactgaa gcgatgatct cgtcgtaatt tcttccaagt
      241 cgatcaatag cttccacaat aaaaatgtct tgatctcgga cgaaatccaa tgcttcttgg
      301 aaaacaggtc gatgagtaat cgttgcgccc gattgtttct cgatgaaaat tctcactgca
      361 ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatgga tgagacacgt
      421 atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaat acaccctaat
      481 catacacgat aaaaccagat ttttcaatgt tgtggtcgtg tctagttagg gtatacctta
      541 tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt taaatggcaa
      601 tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat taaaaatata
      661 ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta agaaaacgtt
      721 ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt atctttaggt
      781 attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc tgatagtaca
      841 aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga taggaacgga
      901 atagccattg gtaacccaac taacgactta actgttactg aaaattattt aatagtttct
      961 ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat gatttttgat
     1021 aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa aagaaatggt
     1081 tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa caattggatt
     1141 gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga atttgtgaac
     1201 acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc gaaagaagaa
     1261 tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa atcaatttct
     1321 aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata tcaaaaagaa
     1381 aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa ttgaaagtgt
     1441 tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca aaaaaacaat
     1501 tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat atggataaag
     1561 ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata cgcccgggta
     1621 tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt tggttgtgaa
     1681 aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt agaaatggcc
     1741 attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg tttaggtaga
     1801 aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt gagttttcat
     1861 agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct catgtttcat
     1921 ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc cgcagcagga
     1981 cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt gtctgaacaa
     2041 gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac tattgcggaa
     2101 cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga ggagaaaaat
     2161 ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg ccatttatct
     2221 agaaaagtga caatagtatg agaatttttt gtaagtgtct actgataact tattctcaaa
     2281 tgttgtaagg attttattca tttgttaata ttaaagaacg gaactccaaa aaagtccgta
     2341 ctctaatttg cagtctctca ctcttttaga gtgagagttt ttatta
//
LOCUS       DAZKPE010000171         2294 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000171 DAZKPE010000000
VERSION     DAZKPE010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.180"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            13..2166
                     /locus_tag="ACG930_002994"
     CDS             13..2166
                     /locus_tag="ACG930_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFQ0520086.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKALELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYTPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTAAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHMNLTIAKEIMDAYYDMFMAK"
BASE COUNT          782 a          411 c          513 g          588 t
ORIGIN      
        1 gaaggatagg aaatgatgaa agattttatg aaaaaaatat taaatacttc ttggttagaa
       61 aaaataagaa aaggtgcaca agaacctaag aacaaaacgt ttcgccggtc ccatgttcct
      121 tttcgcttaa attttctttt tttcattata tttacgttat ttgttgcgtt gattgctaga
      181 ttgggttatt tgcagatcgt gaacggcgaa gagatggagg cgcgagtgaa gtctacttct
      241 acgattacgg tccaagaaag tactcctcgc ggaatgatct acgactccac aggaaaagct
      301 ttagttacga ataaagcgaa tcaggccatc acatatacga gaggaacaca agttacggct
      361 aaagatttgc ttgaaatcgc aacgaagctg aactcgctga tcgatgttcc ggtagatgaa
      421 aatctgacag atagagataa aaaagatttt tggctggctg atcccaaaca tttgaaagaa
      481 gccacaaaaa gactttcggc aaaagaaaag caattaggga acagcgaaca atatagtgcg
      541 atggtcaata aagtcacagc tgatgagatt aatttaaacg aggagcaatt aaaaattgct
      601 accatcttta aacggatgaa tagtgcatat gaattaaaca ctgtctatat caaaaactct
      661 ggtgttactg atcaagagtt agctgttgtg gcagaacgcg cttctgaact tccaggagtt
      721 tcgactggca cagactggac acgagaatat aatgcagcaa gttcactgaa aagtattctt
      781 ggcagtgtga cgactgaaaa gcaaggactt ccagcagatg aagcagagaa atacctagca
      841 aaaggttatt ctcggaatga ccgtgtagga caaagttatt tggaaaaaca atatgaagat
      901 gtcctgcaag gaaccaaaac ccaatatgaa gtttcccttg ataatgaagg aaatgtttcg
      961 aatcaaaaag aaatcttctc tggggaaaaa ggttctaatt taatgttatc tatgaatgca
     1021 gaattccaat caaaagtaga agaaattttg aaaaggaatt atcaaacatt gatcaacaac
     1081 ggcaaagcac agtattcgcc tggtgcttat gcagtggcta tgaatcctca gacaggagaa
     1141 gtgctagcaa tgactggttt cagtcatgaa caaggttcca aagaaatcac cgagaatgct
     1201 ttaggcacga ttactagcgc ctttgatcca gggtctgtag tcaaggctgg tactttgaca
     1261 gcaggctggg caagtaacgc gatcagcgga aatcaagttt tgattgatga gccgattcgt
     1321 ctgcaaggtg cttcagaaaa aagctctgtc tttaatcgaa gcggacaagt tgctcttgat
     1381 gcagtcaaag cattggaatt gtcttctaat acgtatatga tcaaagtggc gttaaagatg
     1441 ttaggactag actatacacc tggaatggga ctacctagtt tagatgaaga agctaaagct
     1501 tatcagcaat tgagagactc tttcaaagag tttggtcttg gtacaacgac tgggatcgat
     1561 ttgccgaatg aatctcctgg gatctcacgt tctgttgatt atatgaagaa gttcaatgcg
     1621 gataatggca aagaatggta tactccaggt aactttaccg atttggcatt tggacagttt
     1681 gacacatata caccaatcca attagctcaa tatgcttcaa cagtcgctaa tggcgggaaa
     1741 cgagtacagc cgcacctagt caaagcgatc tatggcaatg acgaaaatgg aaacttgggt
     1801 gaagtgaaga aagaaattgg cacaacagta gaaaatacgg tcaatatttc tgcagaaaat
     1861 atggcgatcc tccgtgaagg attccaccaa gttgtccatg gtaccgatcc ttacacagca
     1921 gccaaaccat tagccagtgc gaaaatggac ctttccgcaa aaacagggac tgcagaaacg
     1981 gttgcggaag gtcatccaga tattgcgaca gtcaatagta atatcgtggc atacggacca
     2041 acagacaatc cggaaattgc catcagtgtt gtcttgccga acttattaga cgaacaagac
     2101 cacatgaact tgacgattgc taaagaaata atggacgcgt attatgatat gttcatggca
     2161 aaataaaaaa gaggtcgtga aaaagccgct tagtttcgag tatgaagaaa aattttgtga
     2221 aaatagcttc tcacattttt gcttaaattt gacttcatac cgagaaactg gcttttgaac
     2281 accgtttact cggc
//
LOCUS       DAZKPE010000172         2276 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000172 DAZKPE010000000
VERSION     DAZKPE010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.181"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..300)
                     /locus_tag="ACG930_002995"
     CDS             complement(<1..300)
                     /locus_tag="ACG930_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFQ0520087.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACG930_002996"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACG930_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACG930_002997"
     CDS             complement(1014..1304)
                     /locus_tag="ACG930_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520088.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="ACG930_002998"
     CDS             complement(1512..2204)
                     /locus_tag="ACG930_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0520089.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          648 a          432 c          334 g          862 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttt
//
LOCUS       DAZKPE010000173         2262 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000173 DAZKPE010000000
VERSION     DAZKPE010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.182"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            35..769
                     /locus_tag="ACG930_002999"
     CDS             35..769
                     /locus_tag="ACG930_002999"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0520090.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            802..1710
                     /locus_tag="ACG930_003000"
     CDS             802..1710
                     /locus_tag="ACG930_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0520091.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1707..2249
                     /gene="sat4"
                     /locus_tag="ACG930_003001"
     CDS             1707..2249
                     /gene="sat4"
                     /locus_tag="ACG930_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFQ0520092.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
BASE COUNT          796 a          326 c          510 g          630 t
ORIGIN      
        1 gagataaata actttttaaa cgaggagagt tcagatgaaa gaaaacaaat atgatgataa
       61 tatatttttt caaaaataca gtcaaatgag tcgctcgcag aaaggactgg ctggtgcggg
      121 agaatgggag actttgaaaa agatgctacc tgattttaag ggtaagcgtg tgcttgattt
      181 aggatgcggc tatggatggc actgtatata tgcgatggaa aacggtgctt cctctgtagt
      241 aggtgttgat atttctcata aaatgctcga agtagcaaaa ggaaaaaccc attttccaca
      301 gattgaatat gaatgctgtg ccatagaaga tgtggatttc ccagaggaga gctttgatgt
      361 aatactaagt tcgcttgcgt ttcattatgt agcagactat gagaatttaa taaaaaagat
      421 atataggatg ctgaaggctg gtggcaattt agtttttaca gttgaacatc ctgtttttac
      481 tgctcatgga acacaagact ggtattataa cgaaaaagga gaaatactgc atttcccggt
      541 ggacaattat tattatgagg gcaaacggac agctatgttt ttggaagaaa aggttacaaa
      601 atatcataga acactgacca catatctaaa tacactgctt tcaaatagtt ttataataaa
      661 tcagattgtg gagccacagc cgccagagaa catgatggat attccgggga tggcggatga
      721 aatgcgacgc ccaatgatgc tgattgtatc ggcaaaaaag aagatgtaat aatatagaaa
      781 aaataaacga ggagtatgta aatgagatca gaaaaagaaa tgatggattt agtactttct
      841 ttagcagaac aggatgaacg tattcgaatt gtgacccttg aggggtcacg cgcaaatatt
      901 aatataccta aagatgaatt tcaggattat gatattacat attttgtaag tgatatagaa
      961 ccgtttatat ctaatgatga ctggcttaat caatttggga atataataat gatgcaaaag
     1021 ccggaggata tggaattatt cccacctgaa gaaaagggat tttcctatct tatgctattt
     1081 gatgattaca ataaaattga tcttacctta ttgcccttgg aagagttaga taattaccta
     1141 aagggcgata aattaataaa ggttctaatt gataaagatt gtagaattaa aagggacata
     1201 gttccgactg atatagatta tcatgtaaga aagccaagcg caagggagta tgatgattgc
     1261 tgcaatgaat tttggaatgt aacaccttat gttattaaag gattgtgccg taaggaaatt
     1321 ttatttgcta ttgatcattt taatcagatt gttcgccatg agctgctgag aatgatatca
     1381 tggaaggtcg gcatcgaaac aggctttaaa ttaagtgtag gcaagaacta taagtttatt
     1441 gaaaggtata tatccgagga tttgtgggag aaacttttgt ccacctaccg gatggattcc
     1501 tatgaaaaca tatgggaagc attatttcta tgccatcaat tgttcagggc ggtatccggt
     1561 gaggtggcgg aaaggcttca ttatgcctat ccggagtatg ataggaatat aacaaaatat
     1621 accagggaca tgtataaaaa atacactggt aaaaccggct gcctggatag cacatatgcc
     1681 gctgatatag aagagaggcg ggaacagtga ttacagaaat gaaagcaggg cacctgaaag
     1741 atatcgataa acccagcgaa ccatttgagg tgataggtaa gattataccg aggtatgaaa
     1801 acgagaattg gacctttaca gaattactct atgaagcgcc atatttaaaa agctaccaag
     1861 acgaagagga tgaagaggat gaggaggcag attgccttga atatattgac aatactgata
     1921 agataatata tctttactac caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa
     1981 attggaaccg gtacgcttat atagaagata tcgccgtatg taaggatttc agggggcaag
     2041 gcataggcag cgcgcttatc aatatatcta tagaatgggc aaagcataaa aacttgcatg
     2101 gactaatgct tgaaacccag gacaataacc ttatagcttg taaattctat cataattgtg
     2161 gtttcaaaat cggctccgtc gatactatgt tatacgccaa ctttgaaaac aactttgaaa
     2221 aagctgtttt ctggtattta aggttttaga atgcaaggaa ca
//
LOCUS       DAZKPE010000174         2197 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000174 DAZKPE010000000
VERSION     DAZKPE010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.184"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..914)
                     /locus_tag="ACG930_003002"
     CDS             complement(<1..914)
                     /locus_tag="ACG930_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFQ0520093.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="ACG930_003003"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="ACG930_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFQ0520094.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="ACG930_003004"
     CDS             2006..2176
                     /locus_tag="ACG930_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520095.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
BASE COUNT          744 a          384 c          420 g          649 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttt
//
LOCUS       DAZKPE010000175         2183 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000175 DAZKPE010000000
VERSION     DAZKPE010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.185"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            139..972
                     /gene="msrA"
                     /locus_tag="ACG930_003005"
     CDS             139..972
                     /gene="msrA"
                     /locus_tag="ACG930_003005"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFQ0520096.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            1052..2041
                     /locus_tag="ACG930_003006"
     CDS             1052..2041
                     /locus_tag="ACG930_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFQ0520097.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT          790 a          362 c          441 g          590 t
ORIGIN      
        1 ggagaatctg tcgataagga ttctctcttt tttatacgaa aaatctgtag ggggatgaag
       61 taatcgctta tttcctcact ttatgataaa ttacagctaa agtcactagc ttgtcttctt
      121 cggaaaggag gagaatctat ggatgaggaa caaatattca ttcaaacact ttataatctg
      181 attttgaatc cgaatacacg agattgggaa cgaaaagtat tgattcagac aaagaatgac
      241 ataagagaaa atatatccgt taaagaacag ttatcaaaac tagaagcaac actacgtcca
      301 ttagctatcc gaatgaatct gacgcctgat gtaatggact tttatttatt gattacggaa
      361 ggatttgata aggagcaaaa atatgacttt tccaagcatg ccatgcaaga tgctgactat
      421 caagaacgtg cagtatttgc agggggatgt ttctggtgta tggtcgagcc gtttgaatcg
      481 aaaaaaggga tcctatctgt tttgtcagga tacacgggcg gacatgttga aaaaccaaat
      541 tatgatcaag taagtggtgg ttacacaggt catgtggaag ctgtggagat catttatgac
      601 acaagagaaa taagttatag cgagttgctg acaatctatt ggcaaattac tgatcccaca
      661 gatacatttg gacaatttca agatagaggg aagcaatatc gtccagtgat tttttatcaa
      721 ggcgaacgac aaaaagaatt agcggaacaa tcaaaacaga aactagacag ttcaggaact
      781 ttccaccaac caatcgtcac aaaaatcgaa ccagccggta cgttttggcc agcagaaaac
      841 tatcatcagc aattttacaa aaaacaaccg aaacgttata aaaaaatcca gcaagcacgt
      901 aatcaatttc tgatctatca acgagtaaaa aacaaatggc aaaaaaatat acgaaaaaat
      961 cattttgatt aactcctttt ctttaaaatg tagtaaacta aaaatagaaa aaagaaagcg
     1021 ttttaaaaag atttgatgag gaggagaaaa attgtatatt gcagatagtg cacgttatga
     1081 aaaaatggaa tatcgtaaat ccggtcattc aggtttgaaa ttaccgattt tatctctcgg
     1141 attatggcaa aattttggtg attatgatcc tatccataat caaagagaga ttttaagagg
     1201 cgcattcgac atgggaatta cccatttcga ccttgcgaat aattatggag gccctgctgg
     1261 agctgcagag aaaaactttg ggcgtatttt tagagaagat tttcaagcct accgtgatga
     1321 actgattatt tctagcaaag caggttatca tatgtgggaa gggccatatg gggaatgggg
     1381 ctctcgtaaa tccatcattt caagttgtga ccaaagtctc caaagaatgg ggctagatta
     1441 tgttgacatc ttctatcatc atcgcccaga ccctgataca cctttggaag aaacagcaga
     1501 agctttgatg caacttgtaa gacaaggaaa agcattatat attggtatat ccaactataa
     1561 tggagaagat acaaaaaaaa tgactgaaat tttaaaaaga aaggaagcac cgttcattat
     1621 tcatcagatg cgctacaata tgttttctcg tgcactacta gaagacgatc tatctccagt
     1681 attagaagaa gaagggctag gggcaatcac gttcagtccg cttgctcaag ggttgctgac
     1741 aaatcgttat ctacatggta ttcctgaaga ttctagagca catcgtaagg aaataccatt
     1801 cctttcagaa gaacaagttg gatcaactct ggaaaaaatc aaagcactgc aaacaatcgc
     1861 cgtatcacga ggacaatcat tagcgcaaat ggcccttgca tggaatttgc gacaaaaatc
     1921 tgttacaagt gtactggtcg gagcaagtcg gttaagtcag ttacaagaaa gtgttcgaat
     1981 gatggataat ttagatttct caccagaaga agaattgaga atcgaccaaa ttctagaata
     2041 gaaacgatgt aatcaaactt tttatccata tattaaaaaa aacaaaagat gacatcaaga
     2101 atcgaatgaa gatcgtctgt tattgaacat catatttttt gtcgttcaaa ataaaaatga
     2161 tcgaaggcta ggagtgaatt tta
//
LOCUS       DAZKPE010000176         2171 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000176 DAZKPE010000000
VERSION     DAZKPE010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.186"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            790..876
                     /locus_tag="ACG930_003007"
                     /pseudo
     CDS             790..876
                     /locus_tag="ACG930_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1430..1654
                     /locus_tag="ACG930_003008"
                     /pseudo
     CDS             1430..1654
                     /locus_tag="ACG930_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            1914..2168
                     /locus_tag="ACG930_003009"
     CDS             1914..2168
                     /locus_tag="ACG930_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFQ0520098.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLIILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
BASE COUNT          801 a          287 c          348 g          735 t
ORIGIN      
        1 acaaggcttt aggctagaaa acaatagatt atatactact aaaaaataca ataagtacta
       61 ccaatgtcag atatatataa taattatgta ctaccattaa aattaactta tttaataaga
      121 tactactgtg ttaatctgaa aaaaattact ttaaagtagt tacatactac ctgttaaatt
      181 agatactacc attaatactt aaattagata ctacctatat ttatattaag tactaccgtt
      241 ctaggaataa gataataaaa aaaaactacc aaattgcaat taaatactac ttaaaatgta
      301 aaaaataaga actacccaaa ttaggtagtt cttaataaga gaatatcaga taaatttgta
      361 caagtcataa aaaaattaat cttaaatttt taaatatata tacctgttaa ttataaacta
      421 ctttatttag gtagtacata attaacagat aaaactacat gcttgtagtt tgtctagcta
      481 atgagttgca tatgatttat ataaaggtgt gcagcataac ttagttgaag ttaagagaat
      541 agaataaata ttttttgttt tgctaataat taaacactac ctaaatatgg tagtgtttaa
      601 ttatataata ttcattttgt tacaaataat cgtattataa aagcataaca attgggataa
      661 ctatttttta gattatttaa gtactactta aattaggtag tacttaaatt ttggtttaag
      721 gtagtaggta attaagaaat aatatatatc ttcttttata atagaagggg agaggcctag
      781 ttaaaagcag cgacaattaa taacaatgta tttaatgctt cacaaaatcc atttggtgga
      841 caatgcattg ttattagcga tgatctaccg ttctaagtag ttttttctat tggttgcatt
      901 cgtgactaat tatggtataa ttatgagtaa caaagaggta tttcattata tcatcaaacc
      961 ccatcagcgt gtaggctgat ggggtttttt ttacgtttct atattataga attaactggt
     1021 aggcttactg tcttttttgg caattttgca atcaagccac ttgcagatgt agtgtgcagt
     1081 tacctctgca aatggcttga ttgcaaaaac aaaatcaaaa aggtatttca ttatatctcc
     1141 tcctcccctt gccagattag gccggggtag cagacagcaa aactattata acataactga
     1201 aatacctaaa tgacatatac agatatgata atttatgtat tgatttttct aacaaaagca
     1261 catattttaa tatatactac ctattttagg tagtatatat ttttagatac aatatcgatc
     1321 agttttgagg aaatgaaatt ctagatattt tttgctacat agagttactt tcaatatttt
     1381 ttaacgtaat taggcagaag tcactcatcc tctataggtt tgtgatgaaa ttgctattga
     1441 tccatttaag taagagcaaa aaactggagg tttatcaggt aattggtcta atggatttaa
     1501 gtatgcggtc accgtgtata gagttgctta tgagattcaa gaaaataaag ttattccagt
     1561 attgctatat ggaacacata acaattttta tgaattagcc gagaacactc gcaactttat
     1621 tcgtgtagat gaatcggctt cggttgagtt ataactttag ctatatcaat caaccgaccg
     1681 acatatgtta aatctatata taataaaaat acctacttaa atggatgtta acggaagtgt
     1741 atggtgagta gttcactcgt attttgatat cgtttgtata tgttttcagc gttctaagtg
     1801 gcttattttg tccaataata atatggagtg gaatccctta agaaacaccg ttggcaattg
     1861 tcgttataac atgttataat ttatttatca aaaactaaaa gaagtgtgat aacatgggaa
     1921 aagaactaaa ggttagaaag atcggcaata gcgtgggagt gatccttcca agctctcttg
     1981 gattaaaaag cggagacact atccaagcca aacaagaagg caacttaatc atattagata
     2041 ctactcaaat agcaaaagaa cacgatcgca aattgattga agaaagtttc caagactttg
     2101 agaaaggttt aacagtttca gaaattgaaa tggtaaaagc tttcggaaaa tacggctgga
     2161 gtgaatagat g
//
LOCUS       DAZKPE010000177         2048 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000177 DAZKPE010000000
VERSION     DAZKPE010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.187"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..424)
                     /locus_tag="ACG930_003010"
     CDS             complement(<1..424)
                     /locus_tag="ACG930_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFQ0520099.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
     gene            complement(533..1564)
                     /locus_tag="ACG930_003011"
     CDS             complement(533..1564)
                     /locus_tag="ACG930_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0520100.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          629 a          331 c          355 g          733 t
ORIGIN      
        1 gaatctgttt tgattttgtt ccatttgaaa tttctctcac tcgctttttt gtctcatcat
       61 caaataaaat gaaagggtct tctaaacgat cgataaatac ttccattgtt gttgttggta
      121 gatgataaga agtcatgaca ggcactgcac caaggtaaga cacagaaaca gctagaaggt
      181 atgtgtcaaa agcggaactc ttataaataa taactttgtc tccggatttc actccaagat
      241 gagccaattg ataagcccgt ttcaacacac tttcgcagca ttttttgtaa gttgtttcaa
      301 gtcctaattc tgggaaagct gaaagtggct catcaaagat aatcggggtc tcggaaaagt
      361 tagctgcagc ttcttgaaaa ttcgtaaata agttcaaagg ggaatacgtt atggtctcca
      421 tcattcacac tccattatct tttgttaagt aatatacaaa ttcaagataa tcgtaacata
      481 atcctttata taataacata gtttattgtg aaaaaaagat catacatttg ttttatatgg
      541 aagaaacccg aacgaatgcc gctaattcgt gataagaaaa atcaaccatc ttttcccaga
      601 tatcttgaaa agaatgggat gagaggtatc gattaccaca taaataattt accgcgtcag
      661 catcatctaa atatagttct gcataataac gatatgtttt tctgcatagt tctggcgata
      721 cgtttttata tactgtaatt ttgctcaaaa tttggcgaat agtccgagga gaaatttgct
      781 gatcatgtga ggaacgaaaa acaaaagaat tttcgtccgt attttgtgct gttaacttaa
      841 aatagttctc cagaaatggc atcgcttctt ttggtattgg tactttattc agtctgtttt
      901 cttttctatt cagattaaga atctgcttgg tcaaagatac atctttacgt ttaagttcta
      961 ctacttcatg gatctttaat ccgcaataca gaagaatggc agtaattgca aggttcctcg
     1021 gtctattctt ttcttcaaag ctagcttctc tgcttgtttg aaagccttca atcgggataa
     1081 acaaatgctc aaaatctttg aaaagttctg catcgatata tcgcggagct gctttggttg
     1141 tttccggtaa acttgtaccc aaaagagaaa tctcttcttc aatcagtcct ttttgataca
     1201 aaaatcgtaa aaaatgattt aatgaatatt gcttccttga aatcccgtaa tagctatttt
     1261 caaacaattg ctccgtttct tggttcgctg tagtttggaa cgaacgagta tgtcgataga
     1321 ttttagctaa gaaattctga taatcttgtt tttctaaatg gataatcagc tgatcatcca
     1381 cttcttcaga aaatactttt ctcaaataat cagtaaacag atgaaaatct tttgcgtatt
     1441 catagcgact gcctaatgaa agggaagaac gattttcttc taaaaactgt tgaaagacgg
     1501 aagggagcaa gtgtgtacgt tgctttaact tttcttgcag ttgttttcta gttttgctgt
     1561 ccattacaaa ttccctccaa tagtgttcat tttctatatt ttaccgcatt tcatcaaatg
     1621 aagatagaca gtttgtcttg atcttaggaa gcaaattttt aactaagtac tagctaaaag
     1681 atatgaagta agaagataca tttttagtta ttttattagt gcagtcattc ttttgatctt
     1741 ttaattgatt tatcctcttt ttagctatgt ggttacttca tgagcaatga aatggatttg
     1801 gttcgttcta atggcaggag gctctttctt ttatttccga aaaattagaa aacatttttt
     1861 cagaatcgat tggctctcca tttattcaat aatggtttgt ctaacgatat tgttgggata
     1921 attcttaaag aagtattaga aatagttggt acttcattac tttacatgaa gatttattct
     1981 atggtaggag caattatatt gagaattaat ccttttttat ataagttgtt tgcttattga
     2041 tggattgg
//
LOCUS       DAZKPE010000178         1932 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000178 DAZKPE010000000
VERSION     DAZKPE010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.188"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            202..1167
                     /locus_tag="ACG930_003012"
     CDS             202..1167
                     /locus_tag="ACG930_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFQ0520101.1"
                     /translation="MSKRGTIINEWENLTALSNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKINQFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPKEIETWWRLELQ
                     LRRGKATDWHEMVHESLDSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLKQELDTWLLGLDVTEK"
     gene            1367..1549
                     /locus_tag="ACG930_003013"
                     /pseudo
     CDS             1367..1549
                     /locus_tag="ACG930_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          637 a          281 c          430 g          584 t
ORIGIN      
        1 aaaaaaatag tcgagcagtg ttgacgcact ctcgaccttt acggaaacta atcacactag
       61 ctccgtaact tcttaatcat tatacgaata tttttagatt tcttcaagac tagagatttt
      121 ttggtaatga atttttaaga gttacgtgaa cttttgaaaa ttctttccag aagtctcttt
      181 ttctttgagg aggaataaaa tttgagtaaa cgtggcacga tcataaatga gtgggaaaat
      241 ttaacagccc tatctaacag gcggttaaat gttcaaaatt tgaacacccc cctaaaatta
      301 cagtggtcaa ttgaccgaat taccattgtt ggaaaactga aagaaaatat ttattatcat
      361 actcaaaatg atgtattgat tttagacttt gaacagttaa tgcgactgaa tgaaaataat
      421 ggttatgtta aatctgttgg tctaaatggt tggcaaattg tggataagca tgatgagaat
      481 attgcttaca ttgaaatttt gaaatatcaa gaaggtcaag ggcgaattga ctttaatccg
      541 aataaaatta atcagttttt agctagctct atgaagaatt ttatccatga tttatttttg
      601 gagccgcatt tttcacgtgc ggatattgct tgcgatatta tcgatgtgcc tgatgagttt
      661 attacccaat atcgggtggt tgatcctgta tcgtttaaac caatttatgg tcggtctggc
      721 aagttagaaa ctgcttattg gggcagtcgt gctagtgaac gtcaaattcg gatgtataac
      781 aaaaaattag aacaagaaag aaaacggaaa attgttccga aagaaatcga aacttggtgg
      841 cgtttagaat tgcagttgcg acgtgggaaa gccactgatt ggcatgaaat ggttcacgaa
      901 agtttggata gttttgcgag cctgcatttt ttgccgattg atacaacacc tacagataga
      961 ataatgctcg ctggtttaat gtctgatcaa aatttctggt ctcttttgtc gaggaattca
     1021 aaatataaat atcgggaatt gctgaaagaa gaaagtcaaa atgatgaatt gacgaatcat
     1081 ttgcgagaaa cgtttgcaga atcggcagac aatttgaaac aagaattaga cacgtggctt
     1141 ttgggtttgg acgtgacaga gaagtgatac cgaataagaa aagtcagatg agtgagagta
     1201 aatttacgtc aatgtttaat gacgtgagtt tacgataagc gattattttg cgtgaagcaa
     1261 aataaagcgt aaaaggagtt gagagcgtga cacgctttcg gctccttttt tcgttgtcac
     1321 ttgtgacagc gaataccctc ggagagcatt tggaattgtg acagccatgt cacaattagg
     1381 aaaatgttac tctttgtcaa agagtaacag aaaggtttac actcttttta ttagcgacag
     1441 cgcgaaggag gggtttaact tggggtttag tatttcgttc aaaaagggaa caaaaaatac
     1501 aagcatttct cataataatc gtgagttaac tgatagccaa aaaatcaata gtttgtctgg
     1561 tagaaaataa ttagcagatt tacaagtggg aaataaaaag ctgaaagaag aaaattgcat
     1621 ttcaaactac attttctaca ataactctaa aatggcatat tttgcgttct gagcggtttt
     1681 agcgtttatt tcgtttagtt atcggcacaa tcggtgaaac acgttagagg agcgaaaatg
     1741 gagcctgtaa ggcgactggt agcggaacgg tcgtgttaga ttgtgtagcc gatagctgaa
     1801 cgaaataaat gctggcagcg ccattctatt tcggcaggag gaggctcaag gggttcgggg
     1861 aatgaaattc cctgaggtct ttttattttt tctagaggag tgctataatc aaagaaaatg
     1921 agaaaaaaga gt
//
LOCUS       DAZKPE010000179         1908 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000179 DAZKPE010000000
VERSION     DAZKPE010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.189"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            58..852
                     /locus_tag="ACG930_003014"
                     /note="aph(3')-IIIa"
     CDS             58..852
                     /locus_tag="ACG930_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFQ0520102.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1128..1259
                     /locus_tag="ACG930_003015"
                     /pseudo
     CDS             1128..1259
                     /locus_tag="ACG930_003015"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            1335..1828
                     /locus_tag="ACG930_003016"
                     /pseudo
     CDS             1335..1828
                     /locus_tag="ACG930_003016"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT          639 a          309 c          446 g          514 t
ORIGIN      
        1 ataattagct tcttggggta tctttaaata ctgtagaaaa gaggaaggaa ataataaatg
       61 gctaaaatga gaatatcacc ggaattgaaa aaactgatcg aaaaataccg ctgcgtaaaa
      121 gatacggaag gaatgtctcc tgctaaggta tataagctgg tgggagaaaa tgaaaaccta
      181 tatttaaaaa tgacggacag ccggtataaa gggaccacct atgatgtgga acgggaaaag
      241 gacatgatgc tatggctgga aggaaagctg cctgttccaa aggtcctgca ctttgaacgg
      301 catgatggct ggagcaatct gctcatgagt gaggccgatg gcgtcctttg ctcggaagag
      361 tatgaagatg aacaaagccc tgaaaagatt atcgagctgt atgcggagtg catcaggctc
      421 tttcactcca tcgacatatc ggattgtccc tatacgaata gcttagacag ccgcttagcc
      481 gaattggatt acttactgaa taacgatctg gccgatgtgg attgcgaaaa ctgggaagaa
      541 gacactccat ttaaagatcc gcgcgagctg tatgattttt taaagacgga aaagcccgaa
      601 gaggaacttg tcttttccca cggcgacctg ggagacagca acatctttgt gaaagatggc
      661 aaagtaagtg gctttattga tcttgggaga agcggcaggg cggacaagtg gtatgacatt
      721 gccttctgcg tccggtcgat cagggaggat atcggggaag aacagtatgt cgagctattt
      781 tttgacttac tggggatcaa gcctgattgg gagaaaataa aatattatat tttactggat
      841 gaattgtttt agtacctaga tttagatgtc taaaaagctt taactacaag ctttttagac
      901 atctaatctt ttctgaagta catccgcaac tgtccatact ctgatgtttt atatcttttc
      961 taaaagttcg ctagatagag ttctatatta gagatgtaaa gagttttggt gaagaggttt
     1021 gtgagtatgg cttttataac cagggtgcaa tgagaagcac taacagcagc tagcttaaga
     1081 acgcatagga tatacttttt atggaagtca cagaggagga ataaaatttg aacaggatta
     1141 acagagtaac ctctattctt attcagctgc aatcaaaaaa aataattcct gccaaagaaa
     1201 ttgcacagcg atttaatata agcttaagga cagtttacag agatatccgg acacttgaag
     1261 aagccggaat accaattgga tctgaggccg gaaaaggata ttttcttgta gagggcttcc
     1321 tacttccgcc ggtaatgttt acagcggcgg aagtgggtgc attgattaca gcagggaaat
     1381 ttttaaattg ccatggagat gaatcattta taaaggattt tgattcagct atgtataaaa
     1441 tcaaatctat tttgaagcat ggtgaaaaaa actatgcaca ggagttggag aacagtatta
     1501 acgtgtacag cacatctgga cagaaaaata cattggcgga taacgttatt gcagcaattc
     1561 agactgcaat ctgcaataaa agggtaatat caattcaata tcctgcatca ggagggcaag
     1621 aaccggaaag cagaatgata gagcctatat cactggggtt ttatgaacag aactggtact
     1681 taatcggttt tgcaggctaa gaaatgaata taggaatttt cgtgtggatc ggattaaaag
     1741 catttgcata gaagaagagc tctgtcaaag ccatgatggc tctttggaac aaatattaaa
     1801 acaaatgctt tcatataaaa aactatatgc cctacaatgc cgttgtaaaa attggggaaa
     1861 agggatatat tgattttata tctttctcaa aataaacata aaagccct
//
LOCUS       DAZKPE010000180         1888 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000180 DAZKPE010000000
VERSION     DAZKPE010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.190"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..398
                     /locus_tag="ACG930_003017"
     CDS             6..398
                     /locus_tag="ACG930_003017"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0520103.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            399..1838
                     /locus_tag="ACG930_003018"
                     /note="aph(2'')-Ia"
     CDS             399..1838
                     /locus_tag="ACG930_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFQ0520104.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          786 a          138 c          321 g          643 t
ORIGIN      
        1 tttttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
      481 aaagagtatt agaattttat ggtggtagag ataaaaaata tacattagaa tcattaaaaa
      541 aacattatac agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg
      601 ttcctattgg atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt
      661 atccaaaaac tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt
      721 ggagtaaagg aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa
      781 gaaatgctaa tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat
      841 accaaaaatc tggttttaga attattgaag atttgccaga acatgaatta cacgagggca
      901 aaaaagaaga ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg
      961 caatgaaata tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa
     1021 tcggtagtgg ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa
     1081 aatttagtac taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa
     1141 atacaaattt agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg
     1201 aattatctat actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt
     1261 ctactatgtc agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac
     1321 aaatgcacgg tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg
     1381 tattagaaga gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa
     1441 aagattatat agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa
     1501 agtgtttatg ccataatgat tttagttgta atcatctatt gttagatggc aataatagat
     1561 taactggaat aattgatttt ggagattctg gaattataga tgaatattgt gattttatat
     1621 acttacttga agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa
     1681 tgtatggaaa tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt
     1741 atcctattga aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg
     1801 gtagaaaaga aatttataaa aggacttata aagattgatt atataatata tgaaaagcta
     1861 ttataaaaga cattagtatt aaatagtt
//
LOCUS       DAZKPE010000181         1798 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000181 DAZKPE010000000
VERSION     DAZKPE010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.192"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            134..1300
                     /locus_tag="ACG930_003019"
     CDS             134..1300
                     /locus_tag="ACG930_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFQ0520105.1"
                     /translation="MISSKYTIREQNEAKILNQIIRHKEISRAELSKITSLNKASVSS
                     IINKLIDDSLVIENRIGEATNRGRKPIMLTFNGVSSGLAIAIDLGYNYIDGMVASLDG
                     KEIARIQLTDTYVSKDNIQMLIRKIIKKLTDNLPYTRHGIIGMTIAVQGQVLNNKVLS
                     TTYNGLEEIDLVKLLNQEYSFPVFLQNEANLSALGEYTFSSDIENLVSISLHSGIGVG
                     VVKNGKLDIGNKGYAGQLGHTILFPNGRKCECGNYGCLEKYCSTQVIYQEISKEKKLD
                     KINSDIVEYLYSNKDQKVVEMIELYAYYLSIGINNIVMLYAPELVIFNSPLTKKIPNI
                     INIIKNFLNNQYTKEIHIINSPIEWNPVLSGAISFSIQKFLNIEKLKLSSYAKN"
BASE COUNT          684 a          248 c          254 g          612 t
ORIGIN      
        1 tacttgaact aaaattgttt gtacgttaaa ctaattaata aataaaatat aaaataagct
       61 atttaaaatg tcaactgtaa acgctatatt ttttttgcat aggctatttt atttttaaat
      121 tgaggagaaa ttaatgattt caagtaaata tacaattaga gaacaaaacg aggcaaaaat
      181 acttaatcaa ataattagac ataaagaaat atctagagct gaattgagta aaataacctc
      241 tttaaacaaa gcatctgtat cttctattat caataaattg atcgatgact cgcttgtaat
      301 tgaaaataga attggagaag caacaaatcg tggccgaaaa cccattatgt taacttttaa
      361 tggagtatct tcgggcttag caattgcaat tgatctagga tataattaca ttgatggaat
      421 ggtagcttca ttagatggaa aagaaattgc aagaatacag cttactgata cttatgttag
      481 taaagacaac atacaaatgt taattcgtaa aattataaaa aaactcaccg ataatcttcc
      541 ttatacgcga catggaataa tcggtatgac aattgctgtt caaggacaag ttctaaataa
      601 taaagtactt agtacaactt ataacggtct tgaggaaatt gatctagtaa aattattaaa
      661 tcaagagtat agctttcctg tttttttaca aaatgaggca aacttatctg cattaggtga
      721 atatactttt tcttctgata tcgagaattt agtatcaatt agtcttcata gtggaatagg
      781 cgttggagta gtaaaaaatg gtaaacttga cattggtaat aaaggatatg ctggtcagtt
      841 gggacataca attctatttc caaatggcag aaaatgtgaa tgtggtaatt atggttgttt
      901 agaaaaatat tgctctactc aagtaattta ccaagagatt tccaaagaaa aaaaactaga
      961 taaaattaat tcggatatag tggaatatct ttatagcaac aaggatcaaa aggttgtaga
     1021 gatgattgaa ctatatgcat actatttatc gataggaatt aacaatatag ttatgctcta
     1081 tgctcctgag ttagtgattt ttaacagtcc tttaacaaaa aaaattccga acataattaa
     1141 tataatcaaa aattttttga ataatcaata tacaaaagaa attcatatca ttaacagtcc
     1201 tatagagtgg aatcctgttc ttagtggagc aatttcgttt tcaattcaaa aatttttaaa
     1261 tattgaaaag ttgaaactca gctcttatgc aaaaaattaa tttaatttag tggaaactag
     1321 tatgtgaaat ggagaaattt taacatacta gacggctcac cagtactctc tccttaaaaa
     1381 gagcttttta tatagttatg aatttctcac cgctctacct ctttttcaag agataaaaaa
     1441 attaatacaa tgcttattac ttaaactatt tctaactcaa taatctatca aatattctca
     1501 atttttttca attgtctttt tgtttaatca aagcatgctt gcttattatc catttggcct
     1561 atactttagg gtaaaatttt acaatttcat ctaaattata tactaaactt ttatcgctat
     1621 taaaagtaaa aacagcttcg cccacgtata gaaacgtata tctttttgtt tctacacgtg
     1681 ggcgagctga ctaaaatcat ataatcaaaa acttaataaa acgaggttca ctccaatcat
     1741 atttcatttt tcaaaactat cacattaatc tcttgtcaat caaaattatt atacattg
//
LOCUS       DAZKPE010000182         1759 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000182 DAZKPE010000000
VERSION     DAZKPE010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.193"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..141)
                     /locus_tag="ACG930_003020"
     CDS             complement(<1..141)
                     /locus_tag="ACG930_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFQ0520106.1"
                     /translation="MLFNETQLWFKFDPTNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSN"
     gene            complement(147..377)
                     /locus_tag="ACG930_003021"
     CDS             complement(147..377)
                     /locus_tag="ACG930_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520107.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            981..1652
                     /locus_tag="ACG930_003022"
     CDS             981..1652
                     /locus_tag="ACG930_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520108.1"
                     /translation="MGKDKRIVWKDQSDLKIILTISQFIETYEIKSSREYQKQLSKNP
                     HSAPSMWFIINKYGSWNNLLNSIGIDNNGSKKWARMETDELIKVAQIFIDSEKIKSQR
                     VYEKKSAGKDVPCLSTLKNRLGDIRFLFKKEVNKGLTNFEILLELKNEIIRLNMEDDL
                     SMTKFQNYSKSKHLPSVYTIMRRTNKTWEELMSEIGYDYKEIKIKKQRNNLRCRSKKI
                     CSRYE"
BASE COUNT          644 a          236 c          277 g          602 t
ORIGIN      
        1 attagaatag tagagattga ttaataagct atcttcgatt gctaaaaaga aaacttctga
       61 atcccacacc ttataaaaat ctttgacaaa tctattcgta ggatcgaatt taaaccataa
      121 ttgtgtctca ttaaaaagca taaccattac tccgatctgt ttttaaaatt agtttctacc
      181 tctaatatat atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt
      241 acaggttgtt tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat
      301 ttatcttttt tgctgctttg ctcataaaag tctgcatatt catcactgat attttttcta
      361 ataaagtctt ccatcataaa aatcacctca aaacgattat acgaacttac gttctcgttg
      421 taaagcgata tttgaggggc aaaaaggggg caaaaatacg tttatctttg atatatctca
      481 gattgaactt agtgtttatt atatgtcggt attgttgatt tatagctgtt ttgagggtat
      541 tagatacata atagaatata gtggttttgt ttacgtgcat tacacggaaa agctgctcgt
      601 atcaaagaaa tcagaagata aacacggaaa acttccttgg aaatctgaaa tctgtgaaaa
      661 gtccttgtat atcaaggact ttttcttttt tctctatcac atttttaata tgttttgggc
      721 ctttttttct aatgttctct caaattgtcc tgaatctccc aatattgact actattatcg
      781 tcaaaatacc gaaaaaatta gtagtcattt tgacgacaaa tttaatacga aaaataccta
      841 aacacttacc gaatttagca atttttgaac ccgagttgct aaaaaggttg aatgctttcg
      901 aaaaaagcaa aacatatacc attgtgctaa aaagtttatg tgataggttt ctatttaaat
      961 aattttagga gttttttgta atgggaaaag ataagcgtat tgtttggaag gatcaaagcg
     1021 atttaaaaat tatattaaca attagtcagt ttattgaaac ttacgaaata aaatctagtc
     1081 gagaatatca gaaacagtta tcgaaaaatc cacattcagc tcccagcatg tggtttatta
     1141 ttaataaata tggctcgtgg aataatttgc tgaatagcat tggaattgat aataacggat
     1201 ctaaaaaatg ggctagaatg gagaccgatg aattaataaa agtggcacaa atatttattg
     1261 attcagaaaa aataaaatca caacgcgttt atgaaaaaaa gtctgctggt aaagatgttc
     1321 cgtgtttaag cactttaaag aatagattgg gcgacattcg ttttcttttt aaaaaggaag
     1381 tgaataaggg attaactaat tttgagatac ttttagagct taagaatgaa ataattagac
     1441 ttaatatgga agatgattta tctatgacaa aatttcaaaa ctattcaaaa tccaaacatc
     1501 ttccatctgt atatacaatt atgagacgga caaataagac atgggaagaa ttgatgagcg
     1561 aaattgggta tgattataaa gaaataaaaa taaaaaaaca gagaaataat ttgcgttgta
     1621 gatcaaaaaa aatatgttca agatatgaat aaacaaagta tttttcagca tatttttatc
     1681 tgtaccatta ttttaaatat ccatagcagt ttattcatga tttatgaggt ttaaaataca
     1741 atactgaatt cactgctta
//
LOCUS       DAZKPE010000183         1664 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000183 DAZKPE010000000
VERSION     DAZKPE010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.194"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG930_003023"
     CDS             131..505
                     /locus_tag="ACG930_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFQ0520109.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG930_003024"
     CDS             complement(619..1248)
                     /locus_tag="ACG930_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFQ0520110.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG930_003025"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG930_003025"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAZKPE010000184         1613 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000184 DAZKPE010000000
VERSION     DAZKPE010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.195"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            26..286
                     /locus_tag="ACG930_003026"
     CDS             26..286
                     /locus_tag="ACG930_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520111.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(648..887)
                     /locus_tag="ACG930_003027"
     CDS             complement(648..887)
                     /locus_tag="ACG930_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520112.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1224..>1613)
                     /locus_tag="ACG930_003028"
     CDS             complement(1224..>1613)
                     /locus_tag="ACG930_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0520113.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          538 a          232 c          299 g          544 t
ORIGIN      
        1 gaaaaacatt aaggatggat gaaatatgaa taacgaaact atcattttag gaaaaaaata
       61 tatttgccaa cctattggct tgaaacaaaa agtggttgga gaagtaatca gtaaattaga
      121 aaattgtgtt gtgatctgcg tagacgaata tcatgacgtc gatcgcaatg aaatattaga
      181 aaaatgcgga aaagtagtgg caaaatatac tcacgtttat gagttggaaa caacagaata
      241 tctatataac tatagcaaca aatatgaaca tactttagtt tcataaagat ttaaataaag
      301 tgccttcaaa agcgagaaga ccaagctttt gaaggcactt tatttagttg gcagtgattg
      361 ttcatgattt ttgatttatt caaaaggttc gcctagagaa tctgtctctg taacgaggcc
      421 tggtggagaa actcgataaa aacctatact gccagaactg tcctattttc ggatagacaa
      481 actagtagtt ttaaaaagat catccgatcc aatcatttca aaaaatgcaa aactgatatc
      541 aggatcattt agctcaggct tgttatcgta aagcatttgt aaaggttgca tttagttagg
      601 agtaaacgcg aaactatcat cattatttgc tgaagaagat gaagaagcta attcagagtt
      661 tgtttgaaat aaaggagacg tgctgacagt ttctttaccc tgttttttgc agaggtagaa
      721 acttttatat cggaagtttc taccggagaa tttttctcat ttgtagaaat tgttgaatcg
      781 atactattcg aaatttgcgt atctgaaggt atgttctttg atgcagaagt cccacaagca
      841 gtaagtaaca ataaatttga taaactgata aacagaattc ttttcattat gtacacactc
      901 cttatagtat cgtttagcat acacctatgc tcagtattag gcaaaatcaa tgcaaaacta
      961 tcaagtcttt tatagtatct attagtctta gtaatacata tatggagagg gtgatatccc
     1021 agttcaaacc agatacattg gttaccatct gtattaacga ttatgcctct aaacgctttt
     1081 tttatgaaaa aatttataag tgaaaacgta ggtatgatat tatctagagg taattttttt
     1141 gggtatttaa atagttgcta ggaggatagc tgggagcgtc aataattttg tgtaaataaa
     1201 ttgtcctcct gcaaaataat tagttactca gtaaacattg aaactaatgt atcggttacc
     1261 tgttgaaaac ctttatggct tctgtttaga aatttttgat tgtatgtatc aaaaatgctg
     1321 actagaaagc gttctagtga ttcttcattt tgaaactgct cttttctacg gctgtatctt
     1381 ttaatttgct tattgaaaga ctcgattaga ttggttgagt aaatggttct acgaatgcta
     1441 ggtggaaaat cataaaaagt taataagtct tggttttcta tgagtgactg cgtcacttta
     1501 ggatagtttt tcttccattt ctcaatcatg ccggataaga aggtattcgc ttcttctttt
     1561 gagttagctt gataaacagc cttaaagtca tcacagattt cttttcggtc ttt
//
LOCUS       DAZKPE010000185         1583 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000185 DAZKPE010000000
VERSION     DAZKPE010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.196"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            245..>1583
                     /locus_tag="ACG930_003029"
     CDS             245..>1583
                     /locus_tag="ACG930_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520114.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNI"
BASE COUNT          575 a          219 c          282 g          507 t
ORIGIN      
        1 ttttttgtgg ttgtttacgc aaatggcgca aatcttgtac attttaacac aataaaacaa
       61 aaaatataga atatttcctc ataaattttt ccattttttg caatattctc aaaaaaaaga
      121 taaaaaatga gaataactga tgaaaaaaca agcataatcc atcataaaat cagtataggt
      181 gaaaagatga actttcatct gcatatcaag taattggtat gaggcatttt ttgaggtgta
      241 ggatatgaag ttggattacc ttatagaaga ggaagataga gaaaaactgc tgctagctag
      301 atatttagaa tttgagaaaa agaattatgt agtgctgcct aagttatatg aaacattagg
      361 tttgtctaaa tttaaaacaa gaaattatat catagaatta aataaagaat ttactgaatt
      421 caaaacaaag ccagagatcc aaatttcaga agaagcagag atccatgtcg aacgtctgaa
      481 tttgacggat atcaaaaatt taagaagaat ctactttcaa cgatcaaaaa ttgctcgact
      541 gttaacggag atcgtggatt caaaagtaac gatcgaaaaa tttgcagaga atcatttttt
      601 aagcatatca agagcctatg taaaaagaag agaattagtc tcttttcttg aacagcatca
      661 aataaagtta aagaaaaaca tattagttgg ggaagaaata aacatacgga acgtattatt
      721 tggggtatat ttcggggtct ttaatggttt ttctatgcca tttagagaaa gcgtcatgaa
      781 tgaagcaaag agtatcgtgc aatattttga atatctgttc aatttaaaac tgtctgcaac
      841 aaaacgaatc aaattcaatt tgctaaccac tattagtttg ttgagggcct atgggaatca
      901 accaatcgga aaacgtttct tttcagatga atactttaag agctcagaag gaatgaagat
      961 catcaaggat ttatcacata tttcttttct tcatatccct aaagagcaga tcattgatga
     1021 gatttcttat atcatgttgt ttttgatcac ggaagaagaa tttgaattag atggcgcatt
     1081 tggacttgcg gaagctcatt ttcatgatat ccacatgatt agtcaaaaaa tgtcagtgga
     1141 attgattgat caattaccat tttcgattga aatctctgaa gaagaaagac tatatatacg
     1201 aaaagaactt cgtatgggta tgatgcatgt caatcgaaaa aattggatat tcgactttga
     1261 gatgactagc tttacgtcta aaaagcagct acagtttttc ttcgagacgt atccaatatt
     1321 cagtacagca atccaaaagg tcatacaaga gaataaacgc tatttcttgg gaaaagatga
     1381 acgtttcatg attcgcttat tttatgatta tctcttttta ttggtcggta tttgtccggt
     1441 atcatatttt gaagcaccga ttcatgtctg tattgatttt tcgcaaggat ctgcttatac
     1501 cgattacatt atttctcaag tgaaaggatt taaaaattac aatattgtga ttgagagtcg
     1561 aatcacttct cgtacgaata ttt
//
LOCUS       DAZKPE010000186         1432 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000186 DAZKPE010000000
VERSION     DAZKPE010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.198"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            73..1368
                     /locus_tag="ACG930_003030"
     CDS             73..1368
                     /locus_tag="ACG930_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFQ0520115.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          453 a          283 c          267 g          429 t
ORIGIN      
        1 aaaaaaatat agaaaagaca ccctgaaatc ctttagaatt aatttggcta ccaattcata
       61 ggaggattca agatgtctca tactcagctt atcaaagata ccctaaatat tctagaccta
      121 aatatctatt tcgaggaaaa ttgtttaact aaagaaaaat acaaagggca aatttgcttg
      181 atttacaaag gaactcttct gtacaagcca gaagagtgtt cccattgtct ttgtgtcgtc
      241 ccctctagga tcattcgttg ggggacgaca accgttcggt tgttactgaa tgatgtgtct
      301 gagtatcgca cttatctgga gctgaagaaa caacgattta aatgtaagtc ttgccaaaga
      361 acattcgtag cggatacctc tgttgctgaa aaacactgtt tcattagtca aaaagttcgt
      421 tggtctgtca ttgctcgctt aaaagagaat acttccatga cggaaatcgc tcgtcagaaa
      481 aatatttcca cttcttcggt ctatcgtgtc atgaagcgat tctaccgccc attgaatcct
      541 ttcaaacaga ctttgccaaa ggtcttatgc tttgatgaat tcaaatcggt tcgaagtgtt
      601 gccagtgcaa tgagttttat catgatggac ggacaaagcc atgcattatt ggatattgtc
      661 gaaaatcgac gcttgcctta tttagaacgc tatttttctc ggttttcatt agcgactcgt
      721 gaagccgttc aattgattgt tattgatatg tatgcgcctt atgtttcgtt ggtgaaaaag
      781 cttttcccga atgctcagtt gatcatcgat cgtttccaca tcgtccaaca tattggcaga
      841 actttcttga atcatcgagt gaaagaaacc acggtacgac ttaaaggaaa ttcccactct
      901 caacgagggt tagggaaaaa attgaagcgc tattggaaac tcctacaaaa agaagaagca
      961 aagttaaact atgaaaaacg ggtttggcgt gccagtttta aagattattt gactgaaagt
     1021 gagattgccg atcgactgtt agctgcttgt cccaacttac gccaaggcta tcagttatac
     1081 caagacattc tttatgcggt aaagaaaaga gatcagtcac tatttgagga ttgtttaact
     1141 agagacatta gcggtctgcc agaaacctat acaaccactt tacgaacgtt taaaaagttt
     1201 ctgccacaga tccaaaatgc gcttcactac agctattcaa acggaccatt ggaatgctta
     1261 aacaaccaca tcaaagtatt aaaacgcaat gcgtacggct ttcgcaactt ttacaatttc
     1321 aaactacgaa ttatgattcg tcatggcaaa acatttttaa ccaaataaac agaacagaaa
     1381 gaggttttct tctttctgtt ctgtccaaat tattctaaga tttctcttta cc
//
LOCUS       DAZKPE010000187         1384 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000187 DAZKPE010000000
VERSION     DAZKPE010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.199"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            378..1289
                     /locus_tag="ACG930_003031"
     CDS             378..1289
                     /locus_tag="ACG930_003031"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0520116.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT          554 a          206 c          260 g          364 t
ORIGIN      
        1 tcatttttag ttgtataaaa atatatcata ataaaaacaa caaaaaaatg tctggaaaat
       61 cgaacataaa agtgtctgat ttgaatatcc cagcagcgga agaagaaaaa caaaatcgat
      121 aacatttgtt ctaagaatta gttacgttaa atacggaacg caagatagac ttgaaaaacg
      181 gtaacaaaag aagtagtata ttaaggtgtg atgtgctact tgacatttat tctgctgagc
      241 gaactttctg gattgtgtag ccttatatct attcaggacg tatcgagcag attagtaaag
      301 gtgttcttga tgattttcat cttgaacacc tttgttttta gcaattcgca aaaaacgaaa
      361 agtaggagaa ttgataaatg aaaaaaagat ttttagcact tgccatcgta ctaggcactg
      421 gcttattgtc aggctgtacg aatgccggtg aaaaaacagc cgttagttat aaaggcggta
      481 caatcagcga acaagaagta atggatagct tgaaaaaaat gcaaggagca gattccgctg
      541 tgcaacagtt gatcgtttat caagtatttg aagataaata tggagatgac gtatcaacca
      601 aagaaatcga ttctcaatat gatcaaacaa agaaacaatt gggtgattca tttgattcac
      661 aattgaaatc tgcaggttac acagaacaaa cattcaaaga cagtatcaaa caaagtctag
      721 cctttcaaga aggtctaaag aaacatatca aattgaccga tgaagattta aaaacggctt
      781 gggaatcttt ccatccagaa gtggaagctc aaattatcca agtagcaagt gaagatgatg
      841 caaaagatgt gaagaaagct gctgataagg gagacgattt ctctaaatta gccaaagaca
      901 agtcaactga tactacgaca aaagaagatg gcggaaaagt gaaatttgat tccactacta
      961 caacggttcc ggcagaagtc aaagaagcag cctttaagtt gaaagatggt caagtttctg
     1021 atgtgatcac ttctaccaat gcttcaactt atactacgga atattatgtg gttaaaatgg
     1081 tgaaaaacca aaacaaaggc aacgacatgg ataaatacaa aaaagaattg aaagaaattg
     1141 caacagacac aaaattaagt gacagtacct tccagaataa agtaattggc gaagtattga
     1201 aagacgctaa tgtaaaaatc aaagacaaag actttgaaaa tgttttgagt acattcactt
     1261 cagattctag tacagcaagt agtaaataag cggtataaat aaaaaatatg aactatttaa
     1321 atcaataaaa ctgttcatct aaatcttttt attagaacta aatcaacagt agtttaatta
     1381 ctac
//
LOCUS       DAZKPE010000188         1364 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000188 DAZKPE010000000
VERSION     DAZKPE010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.200"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1364
                     /locus_tag="ACG930_003032"
     CDS             82..>1364
                     /locus_tag="ACG930_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFQ0520117.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAZKPE010000189         1364 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000189 DAZKPE010000000
VERSION     DAZKPE010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.201"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..189
                     /locus_tag="ACG930_003033"
     CDS             <1..189
                     /locus_tag="ACG930_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0520118.1"
                     /translation="LVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVT
                     VYEGHFVIAFKSGIEMEI"
     gene            332..556
                     /locus_tag="ACG930_003034"
     CDS             332..556
                     /locus_tag="ACG930_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520119.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            571..>1364
                     /locus_tag="ACG930_003035"
     CDS             571..>1364
                     /locus_tag="ACG930_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFQ0520120.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLY"
BASE COUNT          469 a          204 c          281 g          410 t
ORIGIN      
        1 ttagtagaag atgcctccct cagtggcgag aacgagcgaa tcaatgagct gattgaattt
       61 atccgcaaga acaaattccg caccttagaa tatgatgata agcttgtaag gaagataatc
      121 cagagcgtta cagtctatga aggccacttc gtcatagcct tcaaatctgg catcgaaatg
      181 gaaatatgaa aaccagaagt aaatagccca tgactctaca gtagagttgt gggttttctt
      241 ttgcttgctg attataataa tattttaata actattgtgt ttatcaacca aatggtttat
      301 aatattctta gcgtaaactt ggaggtgctg tatgactacg gcagaaatga ttaaagaact
      361 gtgtgagcaa atgaatataa gtgtttccga acttgctaga cgtattggcc agactccaca
      421 gaatttcaat aaaaaattac aacgagaaac agtaaccttg gatgagttga aggccattgc
      481 tgatgtgcta ggtgtcaagt ttgtgcaggc atttatttta ccagatggag aagaaataaa
      541 aatatctaac gaataaagga ggatgtttat atggtaggta atgttattca aatagtaaca
      601 gagaaattat catctttgcc ttttatagaa ggcatcgtat tagggggctc acgtgcaaga
      661 ggcacccata cagaaaattc tgatatagat atcggaatct attacaattc agactcattt
      721 gacctgacag cgattaatca aattgctaca gaattggatg ataaaaatag aaacaacctt
      781 gttgtgcctc ccggagcgtg gggtgattgg attaatggcg gcggatggtt atttataaat
      841 gggtatcatg ttgacttgat tttacgtgat ataaaacggg tagaacaaat aatcaaagat
      901 acggagcaag gaattgttac tgccaattat cagaccgggc atccccatgg ttatataagt
      961 gcaatgtatc gtggagaatt agcgattagt aaaatactat atgctaagaa cgaaagctta
     1021 tgcgaattaa aaaagcaggc agaaatttac cctactgctc taaagaaaag cttgatgaac
     1081 ttttttatat ttgaagctga attctcttta atgtttgtaa aagcaaatgc gggggtagag
     1141 gataaatatt atattgcagg ccatgttttt cgtattattt catgcttaaa tcaagtacta
     1201 tttgcatgta ataatgctta ttgcattaac gaaaagaaag ctataaaact gcttgaaact
     1261 tttgaatata aacctgaaaa atatgccgaa agagttaatc atatttttga agtactcggt
     1321 ctttctcttt ttgaatgcta cgatatgacc gagaaacttt ataa
//
LOCUS       DAZKPE010000190         1363 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000190 DAZKPE010000000
VERSION     DAZKPE010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.202"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..427)
                     /locus_tag="ACG930_003036"
     CDS             complement(<1..427)
                     /locus_tag="ACG930_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0520121.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLK"
     gene            complement(424..1077)
                     /locus_tag="ACG930_003037"
     CDS             complement(424..1077)
                     /locus_tag="ACG930_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFQ0520122.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          427 a          236 c          128 g          572 t
ORIGIN      
        1 atttaaggct taaatctttc gcatcttttt gcatatcagc tgtagaaaca aattgtagat
       61 ttgttttttt accatcatta agctttattt ctctttcttc aattatcaaa gaattactat
      121 cactttctaa attaacattt atattatctt tgatttgtat ttcattctta ttattttttt
      181 cttttatgaa tacttttatt tcactactct tggaataaaa ctccaaagtt tgttctatat
      241 attttatttc ttttccattc atattactag aaatttcatt tgccatatta tgaatctttt
      301 cttttctcgt ctccaaatat gttttaggaa agataaaaaa aattaatgaa tgaactaata
      361 taattattat tccaagaaca gaaaatattt gtatgaacat ttttggaaat atctttaatt
      421 ttttcatttt ctctccaatt tatatcctac atttcttata gtagttatac agtctaattg
      481 taattttttt ctaagttctt ttatatatac atctattact cgatcataag gagtttcttc
      541 gctatctttc catacataat caataatttg cattcttgtt aacacttgtc cattattatc
      601 caataaacat tttaatactt ctagttcttt tgcatttaca tctatttctt caccatttat
      661 tttagctgta tagctattaa aattaaccga tagatcctta tattcaaact tctctaaatg
      721 tccataattc ttcttaatta aagaatctat tctagctttt aagaccggca atgaaaatgg
      781 cttttctaca tatccgtcta ctaaattagt aaatgcatca attttatatt cttcatcact
      841 aaatgcagtc aagattagaa ttggtaaatt gcttttcttt ctaatttctt tcaacacttc
      901 taaaccattt ataaaaggta tctgaatgtc taagataacc aaatttatat cgctattaaa
      961 ttttgacaag gcttctcttc catctttagc ttgaataaca gtatatccaa attctgaaag
     1021 atattcactt attccctctc ttatcatatt atcatcttca acagttaata ttttcatata
     1081 tacctccact taagcctata cactagatat tatacagcat attatggctc tataatatct
     1141 agtgttggtg acaccttctg ttgccaatac tttttctttt ttctaataaa tgcaaacaga
     1201 caccttgaaa tcctttagaa taaagggttc tataatattt tgtgttgttg gaaaatcgaa
     1261 ggcgattttc tactaacact ttttcttcgt ttcaactcaa aaagagactc acttttggta
     1321 aaatttagtc gaccaaaaca tcaccctacc aaaggagtcg ctc
//
LOCUS       DAZKPE010000191         1348 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000191 DAZKPE010000000
VERSION     DAZKPE010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.203"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(295..540)
                     /locus_tag="ACG930_003038"
     CDS             complement(295..540)
                     /locus_tag="ACG930_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520123.1"
                     /translation="MVDKPKKWQYPLVPLSIILSALEEDPISIKMILKHYDNYIAKLC
                     LTNGFNEVGQFITYVDEYMLRQLEVKLIEAILKFKVN"
     gene            complement(534..935)
                     /locus_tag="ACG930_003039"
     CDS             complement(534..935)
                     /locus_tag="ACG930_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFQ0520124.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNEAKSIRKRNTRIKDNEEPLN
                     DVNEGKYPQTNFDEQDVYFLFGMEILISDQKLSAAIDQLSDIRRKIILLYYFADFNDA
                     EIGRILNMSTSGIWYQRTKAVEQLKMGYDLW"
     gene            complement(1172..>1348)
                     /locus_tag="ACG930_003040"
     CDS             complement(1172..>1348)
                     /locus_tag="ACG930_003040"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0520125.1"
                     /translation="TTQVGKQAKKAKMLPKTGEEDTNMITIFGGLLLLGSLGLIDYKK
                     RESKKSSSRIERSK"
BASE COUNT          422 a          243 c          178 g          505 t
ORIGIN      
        1 cacataggaa tttcacctct ccccaagttt acggcgagcc ttacggaagt atcattatcc
       61 caacctcaaa tcatcgcttt ttattgacta taaaaattat tttagaatat ttatcgctcc
      121 ttctttataa taagagatca tggcgtaact aaaatatgct ccttgaagtg ttaacgtact
      181 gatagaatat atttattttt caatgaacaa taggttttct ccctaaaaga atccgctaat
      241 ctaaagtatt agaagactct ttttggtaga aaaagtagaa aggggagttt ttagctagtt
      301 aactttaaat ttcaatatag cttctattaa tttaacttct aattgcctta gcatatattc
      361 atccacatag gtaataaatt gccccacctc attaaatcca tttgttaaac ataacttagc
      421 tatataatta tcataatgtt tgagtatcat cttgatcgaa attggatctt cttctagagc
      481 agataggata atagatagtg gaactaatgg atactgccat tttttgggtt tatctaccat
      541 aggtcatacc ccattttcaa ttgttcaact gccttcgttc gttgatacca gataccactt
      601 gtactcatat tgagaattct accgatttca gcatcattaa aatcggcaaa ataataaagt
      661 agaataatct tccttcttat atccgataac tgatcaattg ctgctgataa cttctgatct
      721 gaaattaata tctccattcc aaataagaaa tagacatctt gttcatcaaa attagtttgt
      781 ggatacttcc cttcatttac atcattcagt ggttcctcat tatcttttat tctagtgttt
      841 cgttttcgaa tagacttagc ttcgtttcgt aatacttttt tgcagtaggc atcaaattgg
      901 tgttgtatag atttctcatt atagttttgt tgcacgatca atatgctcct ttatcccctt
      961 tccactaata caacaatcag agagtgcctt tttttcgaaa aaactaaaaa aaaacaaaaa
     1021 ataatcatac tttttaggtg gaatttcatt ctcaaaaaaa aaaaaaacga ttagtatcac
     1081 taatcgtttt tgagtattcc ttgcaaaagc caaattactt ttatagttaa aatttgatat
     1141 tgataatcat ccttctttcg gtagtgggta atcattttga tctttctatt ctacttgatg
     1201 attttttaga ctctctcttt ttataatcaa ttaggcctaa acttcccaac aatagaagac
     1261 caccaaagat agtaatcata tttgtatcct cttcacctgt tttgggtaac attttcgctt
     1321 ttttagcttg tttccctact tgtgtagt
//
LOCUS       DAZKPE010000192         1324 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000192 DAZKPE010000000
VERSION     DAZKPE010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.204"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            55..1217
                     /locus_tag="ACG930_003041"
     CDS             join(55..331,331..1217)
                     /locus_tag="ACG930_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFQ0520126.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANK
                     HLYPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSK
                     RGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIV
                     TDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFH
                     TDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQ
                     QLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT          478 a          234 c          265 g          347 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
      721 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
      781 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
      841 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
      901 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
      961 ataaaggctg tccttttgat aatgccgtag ctgaatcaac ttataagtcg ttgaaagtag
     1021 aatttgtcta tcaatacaca tttgaaacct tacaacaatt ggatttggag ttatttgact
     1081 atgtcaattg gtggaaccac cttcggttgc acggtacact tggctacgag acaccggttg
     1141 gttaccgtaa ccagagattg gcgcagcgaa tccttgataa tgagctcgga tgtgctaacg
     1201 ctagcgaggc agtctaactt taactgttag ctcctgccga agatcgtcac atccgaggag
     1261 gctcattgtc aaggacaatc ggaatagcat acggaaagaa gttctgcacc ttataaaatt
     1321 tgtc
//
LOCUS       DAZKPE010000193         1280 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000193 DAZKPE010000000
VERSION     DAZKPE010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.205"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            61..1275
                     /locus_tag="ACG930_003042"
                     /pseudo
     CDS             61..1275
                     /locus_tag="ACG930_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          416 a          254 c          245 g          365 t
ORIGIN      
        1 aaatcaattc taccttagat gttcttatat cactctatca gtcctatttg acaaagagcc
       61 aagaaaaaga cgttggtcgt cgatgctgtt ctctcgccta ctcctcgtgc ttgtagaagt
      121 tgtggttcta ctgtggtaga tggaaacggg aaagcaatta tagtgaaaaa tgggaagaag
      181 gaaacgattg tccgttttga acaatacaat catatgcctt tggttacgcg cctaaaaaag
      241 caacgctata cctgtaaaaa ctgtcgtacc cattggacgg ctcaaagtta ttttgtccga
      301 ctcagccatt caatcgcaga tcatgttcga tataaaattg cttctttact gactgaaaaa
      361 gtatctttgt cttttattgc gaaaagttgt caggtatctt tgactaccgt tattcgtaca
      421 ttgaaagagt ttaaaagcta tttaccaaag ccttctaaga agattctccc cagagtattg
      481 atggttgatg aatttcgttc gcacgcttcc atagaagata aaatgagctt tatttgcgca
      541 gatggtgaaa caggaaactt aattgctgtc ttgcctacgc gtaaattacc tcgattaaca
      601 agctatttct taggctgcac caatccagaa gaagtagaat tcttagtcac agacatgaac
      661 gccgcttact tccagcttac caaacgtgtt ctgccaaatg cgaaagtagt gattgatcgg
      721 tttcatattg tcaaacacat gaatcaggca ctcaatgagt tgcgtatccg tgaaatgaat
      781 gagcttcgta aagcaggaca gaaaagtcag gcagaaaaac tgaaaaagaa ctggcgcttt
      841 ctgctaaaaa atcgtgcaag catcaaccat tatgagtaca aaacatggaa aagtttccga
      901 gcaccaaaat acccatttct cactgaagca atgatgattg atcgattgct tgagttttct
      961 gcgcctctaa aggaggcgta tccctttttt catgaattag tcgaagcctt tcgagacaaa
     1021 gaccctgact tatttttctc cttattggca gaacttcccg aaacgttaga tgacggcttt
     1081 cgggagaagc ttcaaaacct tctgacctat gaagaaggta tcaccaacgc aatgatctat
     1141 ccttattcca atggaaaaat tgaagcgaag aatacccaca taaagacaat gaaacgagta
     1201 tcctacggat ttaaatcatt cgagaacatg agaattagaa tctttttgat caatcaatta
     1261 atcaatgtaa gataacaaaa
//
LOCUS       DAZKPE010000194         1275 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000194 DAZKPE010000000
VERSION     DAZKPE010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.206"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            161..715
                     /locus_tag="ACG930_003043"
     CDS             161..715
                     /locus_tag="ACG930_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFQ0520127.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            771..1271
                     /locus_tag="ACG930_003044"
     CDS             771..1271
                     /locus_tag="ACG930_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520128.1"
                     /translation="MKITEFSEVFKTFSNIYNRIPEIEQNVVVDNDYYIENDFNKPRK
                     YDNLYNFIHNRTTINNNSNTRVLINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAI
                     NNGNLPSNKKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKFL
                     PAFMII"
BASE COUNT          521 a          132 c          226 g          396 t
ORIGIN      
        1 aaaaaagtcg gaatattctg agttactgaa atgatataaa atcataaact aaaccccttg
       61 attttcttca cttttaacag agtatatata taagttcatg attatggtaa aatatatata
      121 taatcatgaa ctcagaatat ttttaagaag ggaaacaata gtgagctata atgtacaacc
      181 gttaaggaca aatgaagaga tacaagattt tcagttttgg ctaagaagaa caagtaatcc
      241 agaaagagat agttttttat ttttgtttgg aatcaataat gggttacgta tgtcagatat
      301 tataggatta aaagttggag acatacgagg taaaagtaag cctattattg ttgaacataa
      361 aacaggtaag cgaaaaccga tttttataga taatttgaga gaagagattt tattatatac
      421 tgaaggtaaa gaagaaaatg attggttatt tccaagtcgg caacaaggtc gacatataac
      481 aagggatcgt gtctatcaga tatatgcaga tatagcagaa aaattaggaa gagatgatat
      541 aggaacacat acattaagaa aaacttttgg gtatcactac tacaagaaaa ctagagacat
      601 tgctacctta atgtttattt ttaatcatag ctcgcaagca attacaaaaa ggtacattgg
      661 tataactgaa gatgaaatag gggcatcgtt acgtggtttt aaattgggag gctaattgag
      721 atattaggat atattttttg tgtataatga aaacttagaa ggtgagatta atgaagataa
      781 ctgaattttc ggaagtattt aaaacgttta gtaacattta caatagaata ccagagatag
      841 aacaaaatgt tgtagttgat aatgattatt atatagagaa tgattttaat aaaccaagaa
      901 aatatgacaa cctatacaat tttatacaca atagaacaac aataaataac aacagtaaca
      961 ctcgagtttt gattaattca gcatattttc atattaaata tttaaagaaa tatgagtatg
     1021 aagaagttgt attagattat gggctaaata gacagtcatt tttaatttat gcaataaata
     1081 acggaaattt gccaagcaat aaaaagaaca taattattga aacatatgcc tatctggagg
     1141 ggggatctaa aaaactaatt aagtcatgta atatagagta tcaattatca gtaggagaaa
     1201 ttaaatgtgt tttcgaagaa gatttagaac ttgacttaaa aaaatttttg ccagcattca
     1261 tgattatata ggttt
//
LOCUS       DAZKPE010000195         1261 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000195 DAZKPE010000000
VERSION     DAZKPE010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.207"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            21..839
                     /locus_tag="ACG930_003045"
     CDS             21..839
                     /locus_tag="ACG930_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFQ0520129.1"
                     /translation="MNYIYLIKEHYPLLTKSEKKVADLILDSGKAIIYSTMSDIKEKT
                     TVGDATIIRFCQKLGFSGFSDLKIEIAKEDFSKKKEYPSSEKYYDIIATHLTEALYST
                     AHLLDEKKLDKAIQLISQAKNLYIFGVGSSGNTSLDLESMFLRVGVQAKAVLDPHFQA
                     QVASLMEEDDVIIAFSLSGKTKDTFDSVEIAKKNGAKILAITNYLHSPIGQTADVVLQ
                     TAIEEFLNGGSLAGKISQLYLCDLLVQGYEQKNNINAVELRERVLRSILDKSLD"
BASE COUNT          481 a          181 c          200 g          399 t
ORIGIN      
        1 tttactgtaa aggagttcat atgaattaca tctatttaat taaagagcat tatcctttat
       61 tgactaaatc tgaaaaaaaa gtagctgatt taatcttaga ttctgggaaa gcaattattt
      121 atagtacaat gagcgatatc aaagaaaaaa ccacagttgg ggatgcaacg attattcgtt
      181 tttgccaaaa attaggattt tctggtttct ctgatttgaa gatcgaaatt gcaaaagaag
      241 atttcagtaa aaaaaaagaa tatccgtcaa gcgagaaata ttacgatata attgctactc
      301 atctaactga ggcgctctat tctacagcac atttactaga tgaaaaaaaa ctagataagg
      361 caatccaact catcagtcaa gcaaaaaatc tttatatatt tggggtgggt tctagtggaa
      421 atacaagcct tgatttagaa agtatgttct tacgagtagg agttcaagca aaagctgttc
      481 tggatcctca ttttcaagct caagtagctt ctttgatgga agaagacgat gtgattattg
      541 ctttttcatt atccggaaaa acaaaagata cctttgattc tgtagaaatt gcaaaaaaaa
      601 atggtgcaaa gatcttagca attaccaatt accttcattc tccaatagga cagacagcag
      661 atgttgtttt acaaacagca atcgaagaat ttttaaatgg tggttctttg gcagggaaaa
      721 tctctcaatt gtacctttgt gatttacttg tacaaggtta tgaacagaaa aacaatatta
      781 atgcagtgga attacgtgaa agagtattac gctctatctt agataaaagc ttagattaaa
      841 tagagtatta attgaagcaa tttatattta ggtgaaatat caattaatta gtgggactca
      901 caatttgcac aaataacttt catcttacct ttagatgaag tgttagaaag aaaagtatca
      961 accatcaata ctttgaaaaa attcttttta taggaatatg atgaacagct ttcaatatac
     1021 aataatcatt atcaaagata actgacaact tttagcaata aaatacaaaa cactttttta
     1081 gtcagtatct aaatataaca aatctatttc ataaagcaaa aaagcggcta gacaaaagag
     1141 atgtctaacc acttacattt atcatctata taattcaatg aacagagaaa aaaaggacat
     1201 cagtttttat caataaaaag tcttgttctt atcaatattt tcagatgttt tagcagatcc
     1261 t
//
LOCUS       DAZKPE010000196         1246 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000196 DAZKPE010000000
VERSION     DAZKPE010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.208"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            200..742
                     /locus_tag="ACG930_003046"
     CDS             200..742
                     /locus_tag="ACG930_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520130.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="ACG930_003047"
     CDS             898..>1246
                     /locus_tag="ACG930_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFQ0520131.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          237 g          354 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tcttgatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAZKPE010000197         1236 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000197 DAZKPE010000000
VERSION     DAZKPE010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.209"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            35..532
                     /locus_tag="ACG930_003048"
     CDS             35..532
                     /locus_tag="ACG930_003048"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFQ0520132.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(569..>1236)
                     /locus_tag="ACG930_003049"
     CDS             complement(569..>1236)
                     /locus_tag="ACG930_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFQ0520133.1"
                     /translation="DLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIEIGYIAS
                     EKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSEALVVIE
                     ADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLYDNLALY
                     EYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKGKRIMVP
                     LPV"
BASE COUNT          433 a          210 c          216 g          377 t
ORIGIN      
        1 atttatagta tactatgtca aaaggaggag ttagatgaac aatcaaatca cactagcgta
       61 tttagattat gatgatctag atgctttaca agttgtaagt gttgtcagtt tttatgaatc
      121 gtttatcgat ggcgcagatc cacttgatat gcaaggatat ttacagacac aattgacaac
      181 tgaaatattg gcagtagaat tggcacagtc aaccagtaaa tttattggta ttaaggatca
      241 tcaaatactc attggttata tgaaagtcaa tgatgaaaaa gatgctatag agattcaacg
      301 gctctatctg ctcaaagatt atcaaaacaa agggttaggg caacggttac tcgatgaagc
      361 gaatcgttat gctaaaacga aacaaaaacg ttatttacgt ttgactgttt atgaaaaaaa
      421 tcatgcaggt attcgttttt atgaacgtca tggatttaaa aaaatcggga tcaaacattt
      481 tcctttagga aaacaagatc gtatttgtcc gattttagaa aaagaaatct aaaaaaacgt
      541 cctcactttt gatgctgagg acgttttttt agactggtaa tggaaccata attcgctttc
      601 ctttttgata aatcgctaat tccgtcacac catttgcttt taacagagca aaaagatcat
      661 cgaaatggaa acggaaatgt tcaaggtaat gcccatctga tccaacacta aacaaggtac
      721 caccacgtga aagatataaa tcgatgacat attcatataa cgctaaattg tcatacaagt
      781 aagcgctctt agcatttaat tcgaatgcca atttattttt gattacttga tctagaatcg
      841 gtaaaaactg cgcttcatat tgtttaaatt cagcaacgga tagaccaaat acccgaaaac
      901 catagtcaaa atgagcaaag acatctgctt ctataacaac tagtgcttct gaaagttgtg
      961 caaaatactg aggaatcaca atagcaggat ccatatcttt gacttcgtca tctaaataat
     1021 caaattgccc attatgatgc acactgagta attttaaatc gtaatcttta tcggctaaat
     1081 agtcgatgat ccgatccttt tcagaagcga tgtaaccgat ttcgatgcct tttaaaacac
     1141 gattgccaaa acgcttattt aagctatcga ttgtttgact gtacatttca taatcgggga
     1201 tatcatcgac tttagtaaca ggattggcta agtcaa
//
LOCUS       DAZKPE010000198         1193 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000198 DAZKPE010000000
VERSION     DAZKPE010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.210"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1076
                     /locus_tag="ACG930_003050"
     CDS             <1..1076
                     /locus_tag="ACG930_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFQ0520134.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAZKPE010000199         1170 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000199 DAZKPE010000000
VERSION     DAZKPE010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.211"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..191
                     /locus_tag="ACG930_003051"
     CDS             <1..191
                     /locus_tag="ACG930_003051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520135.1"
                     /translation="IYHKSDFIPFFLLIAHNRKEKALSRALPPLVVLCTLDRAFCLLY
                     LLARGKKLLVLIIKIVIP"
     gene            complement(156..791)
                     /locus_tag="ACG930_003052"
     CDS             complement(156..791)
                     /locus_tag="ACG930_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0520136.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
BASE COUNT          326 a          251 c          195 g          398 t
ORIGIN      
        1 tgatttacca caaatcagat tttatccctt tcttcctctt gattgcccac aacagaaaag
       61 aaaaagccct gtcaagagct ttgccaccat tggtggtgct ttgcactctt gatcgggctt
      121 tttgtttgct gtatcttctc gcaagaggaa aaaagttact cgtcctcatc atcaaaattg
      181 ttattcctta atacttctcg taacagttcc atatcttctt ttgagttcgg gtttatcatt
      241 ttcacgactt gataaggtgt cttatactta tgtccctcta tgctttcccc aaacatatcc
      301 atactgtata aatcatcata gcggtctaat aatttttgaa acttcaaatg ctggataaat
      361 tctttgattg ggtaaaggtc ggacgcttca atgcttttcc cgttgatata gtctgtaata
      421 tattcccgta acttttctaa ctcatattcc agccattctt cctcgctgtc aaagaagtta
      481 tcatagtgtc catgtttcag ttctgcattt agacgttctt cggctcttaa aaactgacag
      541 acttcctttt cagattgatt gacatacttc cattctcccg acaacaattc attgggcgta
      601 acgtccagca cttccattat cttttccagc gtttcatagg caggatagtt caaccctctt
      661 tcaatcttgg aaaggctctg catattgata ccgattttgt ccgcaagttc ctgttgtttc
      721 attcccctaa attttcttat ggtctgtata ttatttccta aatggcttat tttcattgca
      781 taaccctcca tatctcgtta tatcttcgct attataagtc tatcatgctt aatatgattt
      841 gtaaaggcaa aaaaagatat tgacaaataa gcatataaga attactatgt tcttgtaatc
      901 gaataagcac aatagaatga aatataaaaa cattcaaaaa gaaataccta tctgattaaa
      961 tccgtagata tgaatatcgg ttgaaatgga acttgttaga aaaggcaaaa cagaacttgc
     1021 tgacaaagta tttctgacac ggtggcggaa gcctctcagg cttaccgcca tgacaccttg
     1081 tgtcaagggg aagaaatgct ttgtcggctg gcgagcctgc gagccttgtc tgtgcccccg
     1141 ttatctaaca ggggggcact atttcacaaa
//
LOCUS       DAZKPE010000200         1149 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000200 DAZKPE010000000
VERSION     DAZKPE010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.212"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1149
                     /locus_tag="ACG930_003053"
     CDS             <1..>1149
                     /locus_tag="ACG930_003053"
                     /inference="COORDINATES: protein motif:HMM:NF021909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFQ0520137.1"
                     /translation="NKKLLELKSNPIIKKWRISRLKTGVASIVIFSGVLLSSTIFIPL
                     HTVSAEETVTTTYYDQSKNVSDQLTNINISISNNKEKVIFPHNAESLTSNYAFKVPDS
                     VNPKDYFYIDLSENANFYGVTEANSVTMPNLLAPDNSIIATGKYDIDTNRIQYEFTDY
                     VAVHDNVSGKISLPIFIDPEVVTNTSYQTITASIGNSKKDLSLLVDYSKNVGPQYNAN
                     GAGNIFNVDLNNHNFSHTIYVNSLKQTLGNKSIEIRNQRKEENGYNSEIIYDKTNTQI
                     KVYKVKSNGRLTDSFSIATNDSLEDVTNQCYIDFYDNKINISFPSNIDNETYVVQYTS
                     PYTDKKDIATRVVMYGYSPYQLGNTSWYWDNYVKLTDGNASGDGSVISP"
BASE COUNT          443 a          160 c          171 g          375 t
ORIGIN      
        1 caataaaaag ttattagaat taaaaagcaa tccaattatc aaaaagtgga gaattagtcg
       61 actgaaaaca ggagttgcat caattgtcat atttagcggg gtattattaa gttctactat
      121 ttttatacct ttacatactg tttcagcaga agaaacagta actactactt attatgacca
      181 atctaaaaat gttagtgatc aattaacaaa tattaatatt tcaatatcta ataataaaga
      241 gaaagtcata tttccacata atgcagaatc gctaacttca aattatgcat tcaaagtccc
      301 tgactcagtt aatccaaaag attattttta tattgacttg agtgaaaatg ctaattttta
      361 tggagttaca gaagctaact ctgtcacaat gcctaatctc ttagctccag ataattcaat
      421 tatagcaact ggaaaatacg atattgatac taatcgtatt caatacgaat ttacggatta
      481 tgtagcagtg catgataatg ttagtggaaa aatttcttta ccgatcttta ttgatccaga
      541 agtagtaact aatacttctt atcaaactat tactgcgagt ataggcaata gtaaaaaaga
      601 tttgagtctg ttagtggatt attctaaaaa tgtaggacct caatataatg ctaatggtgc
      661 tggtaacata tttaatgtag acttgaataa ccataatttt tctcatacta tctatgtcaa
      721 ttctttaaaa caaactttag gaaataaaag tattgaaatt agaaatcaaa gaaaagaaga
      781 aaatggatat aattctgaaa ttatctacga taagacaaat actcaaataa aagtttataa
      841 agtaaaatca aacggaagac taaccgacag tttttctatt gctacaaatg attcactaga
      901 agacgtgact aatcaatgct atattgattt ttatgataat aaaattaata ttagttttcc
      961 gagcaatatt gataacgaaa cttatgtcgt tcaatatact tctccttata cagataaaaa
     1021 agatattgct actagagtag ttatgtatgg ttactctcct tatcaattag gcaatactag
     1081 ctggtactgg gataattatg taaaactaac agatggaaat gcaagtggtg acggtagtgt
     1141 gatatcacc
//
LOCUS       DAZKPE010000201         1145 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000201 DAZKPE010000000
VERSION     DAZKPE010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.213"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..107
                     /locus_tag="ACG930_003054"
     CDS             <1..107
                     /locus_tag="ACG930_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFQ0520138.1"
                     /translation="IDSEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            112..1059
                     /locus_tag="ACG930_003055"
     CDS             112..1059
                     /locus_tag="ACG930_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFQ0520139.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          368 a          170 c          244 g          363 t
ORIGIN      
        1 atattgatag tgaagaagat tttaaatggt tagaattttt gtttcctaaa tttttagaag
       61 attcttcgga gcttcaagat atctataatt atttatatcg gaggtaaaag gatgagctgt
      121 tatcttatca ccggtggggc tggcttcatt ggttctacct tagccaatca tttaggagaa
      181 gaacatgtgg taatcgtcgt cgatgactta tcaatgggaa aagtagaaaa tcttgatatg
      241 acgaaaaata tcacttttat tgagggagat gtcgctgaga aatccttgat ggaagagatc
      301 atgaaagcta ataaatttga ttatatcttt catttagcag cagttgctag tgtggcagat
      361 tcagttgccc gaccagtaga aacacatcgt gtgaattttg aaagtgtatt aatgatttta
      421 gaattgatcc gcaagtatca acctgattta aaacggatcg tgtttagttc ttcagcggct
      481 gtttatgggg atgaaccgac tttaccaaaa aaagaagagt ccgtgattcg cccattgacg
      541 ccttatgcgg ttgataaatt cgctgcagaa caatatgtgc tagattattg tcatttatat
      601 gatgtacccg gtagcgcagt tcgttttttc aatgtctatg gtccaaatca aaatccgaat
      661 tctccataca gtggtgtgat ttctattctc gtagatcgct ataagaaaca aatcgtagga
      721 gaagcaactt catttacatt atttggtgat ggaagccagt ctagagactt tgtttatata
      781 gatgatgtaa tccaagcatt acttttagtt gcgaatgagg aagctgcact ggggaaacaa
      841 ttcaatgttg gaacgggtaa agcaaccaca cttttggaat tgattcatgc aatcaatgaa
      901 attctcggtg tagaattgac acttgaatac aaagaagagc gttcgggtga tatccatgac
      961 tctctagcag atattactaa gatccagtca attggctatc aaccgaaata tggtatttta
     1021 agtggaatga ctaattattt gaaaactgaa atcaattaaa acatactaag ataagattag
     1081 agggtaaatt caggctcttt gtcaataagg actgatgagt tttgtaaaat caaatctggg
     1141 ataga
//
LOCUS       DAZKPE010000202         1116 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000202 DAZKPE010000000
VERSION     DAZKPE010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.214"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            24..248
                     /locus_tag="ACG930_003056"
     CDS             24..248
                     /locus_tag="ACG930_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFQ0520140.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            245..>1116
                     /locus_tag="ACG930_003057"
     CDS             245..>1116
                     /locus_tag="ACG930_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFQ0520141.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSG"
BASE COUNT          373 a          187 c          239 g          317 t
ORIGIN      
        1 actttattta gggagagaag aaaatgaata ataaaacgtt cgaagtacta aaatggttcg
       61 cactggtaat tattcccgca ctagctactt tcgtggggtt agttggtaaa gcgctcaatt
      121 ggcagtacac agatatctgt gttgtcatca ttactggttt tggcgcgttt ttagggagtg
      181 tgttgggtgt atcaaatcga acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa
      241 acaaatgaaa aagaaaatta ctattactgc gatgagcctg ttaacggctc tttttttatt
      301 acccattaat acgtttgctt atactattaa tgacgagtat aatttagcgc cgaatcaagg
      361 agactccaga ttagcaattc ctaacaaaat tattttgcac gaaactggaa tagatgcacc
      421 agcaagaaac gtagccgcca acatgaaaaa taattataac ggaagcaatt cttatactac
      481 agatgttatt ggtgacggtg ggattgttta ccgtgtgggt gagcaaggat atgtttcgtg
      541 gggagctggt aacgctaatc cttatgcgcc tgtacagatt gaattacagc gcacatatga
      601 taaagcattg tttgaaaaaa actatcgagc ttatattgaa tatacaagag atagtgcaaa
      661 aaaatatgga attccattga ctcttgatca aggaacttct ttatttacaa aaggaatcat
      721 ttctcatttg tgggtgacaa attatgtttg ggggaaccac acagatccat atggttactt
      781 atcgcaaatg ggagttagca aagaaaagct tgcttatgat ttagctcatg gatttaccga
      841 tgaaaatcca acaacttctg aaaacaagcc tgtcattgat ccaacacgag ctggtgcagc
      901 taatcctacg ctgacagatg gaacaaatca cgcccacatt gatcagtttg gggaaatcga
      961 aaacgcaaac ttgcatgtgg ctggatggca cattgctaac tataaatacg agtatatttt
     1021 cattatggac tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag
     1081 accagatgta aaccaagctt ataatacttc tggaaa
//
LOCUS       DAZKPE010000203         1087 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000203 DAZKPE010000000
VERSION     DAZKPE010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.215"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(15..>1087)
                     /locus_tag="ACG930_003058"
     CDS             complement(15..>1087)
                     /locus_tag="ACG930_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520142.1"
                     /translation="VFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFS
                     LLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRY
                     NYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP
                     FFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNG
                     NKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTS
                     IFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKN
                     EFMQFGLTVLGICTFIITVINR"
BASE COUNT          415 a          181 c          140 g          351 t
ORIGIN      
        1 ggattttttg tatattatct gtttatcacc gttattataa aggtacaaat accaagcacg
       61 gttaatccaa attgcataaa ttcatttttt tgtacactca tgcttttcat tagctcttta
      121 actgccatta gtactaagat ggcgataaca acataaagta tatagtacgt ccgcattccg
      181 gaagcccata ctgtgggaga aaatcccata attaaccttg aacaaaatcc cattatcatc
      241 aaaataacta aaaaaataga agttttctta ttgtcaaaac ttaaataaat tccaacaatt
      301 aaacatagta ataatgccaa gactactaaa gtagctatcc aagtacctgg ataaaaaagt
      361 gacagtttcg ttcctaactc tgtaaagaga ttattcaggt tactactact ccaaatcatt
      421 gcccttttat ttccattgac gtaagtaaag ctttgaccca ttgtattacc aaaataaata
      481 atcaggttta agaaaaacgg taatgcagtc aatatacgca cataatagtt ttgacatttc
      541 ctatatgtta gaaggaaaat taagaaaaat agcaataaaa ataagatatt catgtctaaa
      601 aaaaacggct ttccaaatga tgaaatacct aaatctaact tattaagaaa gttgaaattt
      661 ttatattcag gaaaccattt attaatttca tgtgcagcac gtaatgcatt ccctggagtt
      721 gtcaaagaga aaattaattc tgctaagctt attattgaaa atactgataa cttataatta
      781 tatcgtccat tgacaatcaa atataaacta actatacttg ttagaacaaa aaaacaggcg
      841 ttgacttgtt cttgattagt taaaaatatc aataaaggaa tacttaccca atatattttt
      901 ctatttattt cttctcctct taagagttga aaaaacggat aaaaagttag taaactaaat
      961 gctactggcc actgatagtt caaggtggtt gctctccaac cggtttcccc cattactgtc
     1021 aatggtatta aacagtatat agagcaaacc aataataaat ttttaacatt tattttctca
     1081 aaaacat
//
LOCUS       DAZKPE010000204         1075 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000204 DAZKPE010000000
VERSION     DAZKPE010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.216"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            326..>1075
                     /locus_tag="ACG930_003059"
     CDS             326..>1075
                     /locus_tag="ACG930_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520143.1"
                     /translation="MFTSCKEKRLKFAIRKKKGGGAASFIIGCLIFGNIFLNGAIANA
                     SSIENSYAISGFGNQTKGGYFLYNKGIKTESVIDNQVAFCFDKNVIAKLNDRGFSNPG
                     YQLYNEKDEQLLKVYSNEKINKVRNIMAYAWDNFITKYPYLNTYTAASNDDRASLARG
                     ISHAIWVTLGQTTEKKSRSDLGGVNTNAYKFYKEALNYKPLAKDINNYDISLLIPTDD
                     NNILQVNASQSLITVKKIDPDKPVNPDPETPV"
BASE COUNT          391 a          139 c          177 g          368 t
ORIGIN      
        1 ttttcttata aatagtttta tcttatttac aaatataata gaactcagtg gacttattcc
       61 cagatagttt ttagataaca ctgatagtga aatgttgaag caaaattagc attgattacc
      121 tgtctaattt taatgtttta tagtgagtct acctgaaaat aaaagtgcct catcataatt
      181 gtttcttaaa aaataaacga tcattttttt attgaaattt ccggaaaatt aatttatact
      241 tttatcgaaa aacattctaa tttgaatgct ttttcttttt gtctataaaa catgaacgtt
      301 cattttgtgg taaggagaga tgggaatgtt tactagttgt aaagaaaaaa gattgaaatt
      361 tgcaattaga aagaagaaag gtggtggtgc tgcgtccttt ataattggct gtttaatttt
      421 tggaaacata tttctcaatg gcgctattgc taatgcgtct agtatagaaa atagttatgc
      481 aataagtggt tttggtaatc agacaaaagg tgggtatttc ttatataata agggtattaa
      541 aactgaaagt gttattgata accaagtagc tttttgtttt gacaaaaacg ttatagctaa
      601 actgaatgat cgtgggtttt caaaccctgg ttatcaatta tacaatgaaa aagacgaaca
      661 actcttgaaa gtatatagta atgaaaaaat taataaagta agaaatatca tggcttacgc
      721 ttgggataat tttattacta aatatcccta tttaaatact tatacagccg cttctaatga
      781 tgatcgtgct tctcttgcca gaggaattag tcatgctatt tgggtaacct tgggacaaac
      841 aacagagaaa aaatcaagaa gtgatttagg tggcgtaaat actaatgctt ataaatttta
      901 taaagaagct ctaaattaca agccacttgc aaaagatatt aacaattatg atattagttt
      961 acttattcca actgacgaca ataatatttt gcaggtaaat gcttctcaat cattaataac
     1021 ggttaaaaaa atcgatccag ataaaccagt aaatccagat ccagaaactc cggta
//
LOCUS       DAZKPE010000205         1064 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000205 DAZKPE010000000
VERSION     DAZKPE010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.217"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..>1064)
                     /locus_tag="ACG930_003060"
     CDS             complement(39..>1064)
                     /locus_tag="ACG930_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFQ0520144.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          177 c          160 g          381 t
ORIGIN      
        1 ttttagaaaa agcagtcgga ctttctaaaa gaagttcact attcgatcct gtcgatgatt
       61 tcttcaggaa aatcgtctat ttgcttgtca attttgctgt ctttgtattt ctcttcttgg
      121 atagtcaaca aaatctttgt aagattcccc cagtctactg ctcttggcgg atcgagccaa
      181 accactactt gagatgcact ttcttcatat agattattcc tattcgtgat tataacatcc
      241 gggaactcag gctttcctgc ctctatcact tccgtgttca gattaatgta caagcttaaa
      301 tttttcttga taaattgatt ataggcagca ccataagaaa aatcgatgat gatctttact
      361 ggttcagaaa tcagttgaat gggtatgtga ttgatcaata ataataaata actgaaaaaa
      421 agaaaaaatt tatcttgaag caactctttg cgttttgacg ttagatcatt tatatactct
      481 atcaaatagc aataaaatgc tggatagttt tctctaaaaa aagaaacatc aagtggaaat
      541 tcatcagctt tattaatagt gtaatgcaaa agtttaaaat gtattttggt taactctctt
      601 cggatcaatt ggctcgtctc ttctcgcaac agattaaact gattttcaaa actttcaatg
      661 aatcgttcat tcaaccattc gattgtttca tcttcatttt ttctcaagta tttttgatcc
      721 aatttatcat gaagataaag ccaagagagt gtcttattga taaaaataac ggatttttct
      781 cctaatactc cttttaagtg gtaaaatcct atatccgaaa aaaatagcga ctgattgcta
      841 gcaatatcta aagaatcagc ttgttcagcc aacaggttga ttgctaaaaa gtggaataat
      901 ttcttttttt cataagcaga cagaggataa tactgtttta aatcttttaa cattttttct
      961 gtttttataa ttataggtag cgtatacaat tccacaaaac ttatctctgt tgagttaaaa
     1021 agattatata aaaaaagccg aatgttttta ggattccctg tcaa
//
LOCUS       DAZKPE010000206         1032 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000206 DAZKPE010000000
VERSION     DAZKPE010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.218"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            25..>1032
                     /locus_tag="ACG930_003061"
     CDS             25..>1032
                     /locus_tag="ACG930_003061"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFQ0520145.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
BASE COUNT          425 a          170 c          183 g          254 t
ORIGIN      
        1 ctaattacag gagtgcaaat tttaatgaaa aaaaaatcaa ttattttggc agctactagt
       61 gcgttggctg ttttaactct agcagcttgt tcaggcgata ctaataaaga tatcgcaacg
      121 atgaaaggcg gaacgatcac tgtatctgat ttctatgatg aagcaaaact tgaatcatcg
      181 aaccaatcct tagtacaacg gatgatcatt tataaagtat tcaataacaa atatggcgat
      241 aaagtaaccg ataagcaagt ggatgcagaa tacgacaaac aagcgaaatc attaggtgat
      301 acttttgaat cacaattaga agctgctgga tatacgaaag atacttataa agaatatatt
      361 cgtaacaatt tagcttttga agctggcttg aaagctcacg tagatattac agatgacgat
      421 ttgaaaactg cttggaaatc tttccatcca gaagtagaag cacaaatcat caaattatca
      481 agtgaagatg aagcaaaaga tgtgaaaaaa tcagcggatg atggagatga tttctctaaa
      541 ttagccaaag acaaatcaac tgatacagag acaaaagaag atggcggtaa agttaaattc
      601 gactcaacga caacaactat tcctgcagaa gtaaaagaag cagctttcaa attgaaagac
      661 ggtgagatct ccgatgttat tactacaaca aatcctactt cttatgcgac agaatactac
      721 gttgtcaaaa tggtgaaaaa ccaaaataaa ggcaatgaca tggataaata caaagatcaa
      781 ctaaaagata tcgctactga aactaaacta agtgacaatg cattcacaac taaagtaatc
      841 ggtgaagaat taaaagatgc aaatgtaaaa atcaaagatg atgcctttga aaatgtgttg
      901 agtgcattca caacaacttc atcaagtacg aaagactcaa gtgaaactac agcttcaaca
      961 aagagttctg acacaaaatc aactgattca acaaaagaat cttcaactga agaaacaact
     1021 gattcatcaa aa
//
LOCUS       DAZKPE010000207         1006 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000207 DAZKPE010000000
VERSION     DAZKPE010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.220"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..569
                     /locus_tag="ACG930_003062"
     CDS             <1..569
                     /locus_tag="ACG930_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFQ0520146.1"
                     /translation="HLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSD
                     YDLIIIDTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGL
                     DMIGFVPYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKG
                     YDKKVLSMYENVFFEMIERIIQLENEKE"
     gene            689..898
                     /locus_tag="ACG930_003063"
     CDS             689..898
                     /locus_tag="ACG930_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFQ0520147.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            915..>1006
                     /locus_tag="ACG930_003064"
     CDS             915..>1006
                     /locus_tag="ACG930_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFQ0520148.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVL"
BASE COUNT          390 a          140 c          193 g          283 t
ORIGIN      
        1 ttcatttgac tgataattta gacttgatcc ctggcacgtt tgatttgatg ttactgccaa
       61 aattaactcg ctcatggacg tttgaaaatg aaagtagatt gcttgctact cttttagcac
      121 ctttaaaaag tgactatgat cttattatta ttgatactgt accaacgcca agcgtttata
      181 caaataatgc aatcgtggcg agtgattacg ttatgatccc tttacaagca gaagaagaaa
      241 gtacaaacaa cattcaaaac tatatttcct atttgattga tttgcaagaa cagtttaacc
      301 ctggactaga tatgattggt tttgttcctt atttagttga tacggacagc gcaacgataa
      361 aatcaaacct ggaagaactg tacaaagaac ataaagagga taatttggtt ttccgaaata
      421 ttatcaagcg aagtaataaa gtaagtactt ggtctaaaaa tggcattaca gaacacaaag
      481 gctatgacaa aaaagttttg tctatgtatg agaacgtatt ttttgaaatg attgagcgaa
      541 tcattcaatt agaaaatgaa aaagaataga atcacaaatc acaagtgatt aatcacaaat
      601 cacaagtgat taatcacaaa tcacttgtga tttgtgatag gtgatgataa aataaatagt
      661 aagaagaaat agaaagaagt gagcgatcgt gggaaattta ggcgcacaga aagcaaaacg
      721 aaatgatacg ccaatcagcg caaaaaaaga tataatgggg gataagacgg ttcgtgttcg
      781 tgccgacttg caccatatca taaaaatcga aacagcaaag aatggcggaa acgtaaaaga
      841 agttatggat caagccttag aagaatatat acggaaatat ttacctgaca aactttaaaa
      901 ggagtgaaaa tgaaatggca gttacgtatg aaaaaacatt tgaaattgaa atcattaatg
      961 agttatcggc aagtgtttat aatcgggtat taaattatgt tttgaa
//
LOCUS       DAZKPE010000208         1005 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000208 DAZKPE010000000
VERSION     DAZKPE010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.221"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1005
                     /locus_tag="ACG930_003065"
     CDS             <1..>1005
                     /locus_tag="ACG930_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0520149.1"
                     /translation="VSENNFKNLSFTISDSEISELTGDIFNYEIKRYSISGIVITIQN
                     VGEKLKISFEPTDSFQYLSKDIEIEDIYKILAQELSKNVISLPKVFYFPAERTGINVF
                     KNELNESRLKTYDTLLNTVQFTNLTNQKKKAALKYDLLKKNIELLMETTDNSSYPKPI
                     SDYINYLNNMKNRYEQKNVNNIASYIRDEIIMGKYEIDEKDNSVSFRQKFGKNRYRKE
                     RIPFHVVSSSIKSLYGLDYYLENSSKEGDYLIIDEPELSLHPENQVKLAKVITDIVES
                     KIKLITSTHSDLFVRELTNIVIENKLNSKNNKKNKLSDKNIGIYNFVGNNDINELEKI
                     "
BASE COUNT          417 a          108 c          156 g          324 t
ORIGIN      
        1 aagtaagtga aaataacttc aaaaatcttt cttttactat ttcagattca gaaattagtg
       61 agctcactgg tgatatcttt aattatgaga tcaaaagata cagtataagt ggcattgtta
      121 taacaattca aaatgtagga gagaaattaa aaattagctt tgagccaact gattcatttc
      181 agtatcttag caaagatatt gaaattgaag atatttataa aattttagct caagagctat
      241 ctaaaaatgt tattagtttg ccaaaggttt tttattttcc agccgaaaga actggtataa
      301 atgtctttaa gaacgaacta aatgaaagtc gcttaaaaac atatgatacc ttgctgaata
      361 ctgtgcaatt tactaattta actaaccaaa aaaagaaagc tgccctcaag tacgatctgt
      421 taaaaaagaa tattgagctg ttaatggaga caacggataa tagttcttat ccaaagccaa
      481 tatcggatta tattaattat ctgaataaca tgaaaaatag atatgaacag aaaaatgtca
      541 ataatatagc atcatatatt agagatgaga ttattatggg taaatatgaa attgacgaaa
      601 aagataattc tgtaagtttt agacaaaagt ttggtaaaaa tagatataga aaagaacgaa
      661 ttccttttca cgttgtgtct tcttcgatta aatctctata tggattagat tattacttag
      721 aaaattcaag taaagaagga gactatctta ttattgatga gccagaattg agtttacatc
      781 cagaaaatca ggttaagtta gcaaaagtaa ttacagatat agttgagagt aaaattaagc
      841 taattacttc tacccatagt gatttatttg tacgtgagct tacaaatatt gttattgaaa
      901 ataaattaaa tagtaagaat aataaaaaaa ataaattgtc tgataaaaat ataggcatat
      961 ataattttgt aggaaataat gatataaatg aattagaaaa aattt
//
LOCUS       DAZKPE010000209         1000 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000209 DAZKPE010000000
VERSION     DAZKPE010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.222"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            369..1000
                     /locus_tag="ACG930_003066"
                     /pseudo
     CDS             369..1000
                     /locus_tag="ACG930_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAZKPE010000210          989 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000210 DAZKPE010000000
VERSION     DAZKPE010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.223"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>989
                     /locus_tag="ACG930_003067"
     rRNA            <1..>989
                     /locus_tag="ACG930_003067"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          307 a          196 c          285 g          201 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctc
//
LOCUS       DAZKPE010000211          988 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000211 DAZKPE010000000
VERSION     DAZKPE010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.224"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..979
                     /gene="bsh"
                     /locus_tag="ACG930_003068"
     CDS             5..979
                     /gene="bsh"
                     /locus_tag="ACG930_003068"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFQ0520150.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          349 a          127 c          174 g          338 t
ORIGIN      
        1 aactatgtgt acgtctatta cttatgtaac aagtgatcat tattttggaa ggaattttga
       61 ttatgaaata tcttacaatg aagtagttac tgttactcca agaaattata agttgaattt
      121 tcgaaaggta aatgatttgg atactcatta tgcaatgatt ggtattgccg ctggtatagc
      181 tgactaccct ctttattacg atgcgacaaa tgaaaaagga ttgagtatgg ctgggctaaa
      241 tttttctggg tatgctgatt ataaagaaat acaagaaggg aaagacaatg tatctccttt
      301 tgaatttatt ccttggattt taggacaatg ctcaacagta ggagaaacta aaaaattgtt
      361 aaaaaatatc aatttagcaa atataaatta tagtgatgaa cttcctttat cccctttaca
      421 ttggctatta gctgataaag aaaaatcaat tgtcattgaa agtatgaaag atggacttca
      481 tatatatgat aaccctgtgg gcgttcttac caataatcct tcatttgact atcaattatt
      541 taatttaaac aattatcgtg tcttatcgag tgaaactcct aaaaataatt tttcaaatca
      601 aataagtttg aatgcctata gccgcggtat gggagggata ggcttgcctg gagatttatc
      661 ctcagtatct cgttttgtta aagcgacttt tacgaagctg aattctgtat ctggagattc
      721 agagtcagaa agtattagtc aatttttcca tatcttaggt tcagtagaac aacaaaaagg
      781 tttgtgtgat gttggtgatg gaaaatatga atatacaatt tattcttctt gttgcaatgt
      841 tgacaaagga atctattatt atcgaacata tgaagacagt caaattactg caattgatat
      901 gaataaagaa gacttagata gtcataagtt aattagttat ccaattatag aaaaacaaca
      961 aattaaatat ataaattagt taatgtgt
//
LOCUS       DAZKPE010000212          959 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000212 DAZKPE010000000
VERSION     DAZKPE010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.225"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..830
                     /locus_tag="ACG930_003069"
     CDS             <1..830
                     /locus_tag="ACG930_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFQ0520151.1"
                     /translation="IVHNQVYFGGGINLWLAKKNGIRQRIAHSHATEDGKSQNIVMNV
                     LRKFLTKLLLQNATDYLAVSQEAGESLFQNHPFEIVHNGIDLELYSKNSEAKVNKRKE
                     LDISMSTFVVGNIGRLEKQKNQSYLLEIFLEILKMNSDSYLILVGEGSLRNKLKAKAV
                     ELDIEKRVKFLGERNDIPELLSVMDVFVMPSLYEGLPMVGLEAQAAKLKLVLADTISK
                     DTKLTNNVDFVSLDETPQEWAKKVIKEPYANKITQELKSYDVSYTTEQMESIYSRDH"
     gene            863..>959
                     /locus_tag="ACG930_003070"
     CDS             863..>959
                     /locus_tag="ACG930_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HFQ0520152.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIH"
BASE COUNT          367 a          110 c          184 g          298 t
ORIGIN      
        1 ctatagttca caatcaggtt tattttggcg ggggaattaa tttatggtta gccaaaaaga
       61 atggaatcag acagagaatt gctcatagcc atgcaactga agatggaaaa tctcaaaata
      121 ttgtaatgaa tgtattgcgt aaatttttaa ccaaattgtt gttacaaaat gcaacagact
      181 accttgccgt tagtcaagaa gctggtgaaa gtctgtttca aaaccatccc tttgagatag
      241 ttcataatgg tattgattta gagctttata gtaaaaattc agaagctaag gttaataaga
      301 gaaaagaatt ggatatctca atgagtactt ttgttgtggg aaacattgga cgattagaga
      361 aacaaaaaaa tcaatcttat ttgttagaga tttttttaga aatactaaaa atgaattctg
      421 attcttactt gattttagta ggtgaagggt cacttagaaa taaactgaaa gccaaagcag
      481 tagaattgga tatagagaaa agagtaaaat ttttaggaga aagaaacgat attcccgagt
      541 tattatctgt gatggatgtt tttgtaatgc cttctcttta tgaaggtctg ccaatggttg
      601 gattagaagc acaagcagca aaattaaaat tagtcttagc agatactatt tccaaagata
      661 caaagttaac aaataatgtg gattttgtat cattagatga aacaccacaa gaatgggcaa
      721 aaaaagtaat aaaagagccg tatgctaata aaataacaca agaactaaag agttatgatg
      781 tttcgtacac tactgaacaa atggagagta tatatagtag agatcattaa aaatgttcaa
      841 gatattttag gagtgattat ttttgaaaat atgttatttg atattggcat acaatgatat
      901 tggcaactta aagagattgg tcaatcgatt gaacgaaaat gcagttttta ttattcata
//
LOCUS       DAZKPE010000213          956 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000213 DAZKPE010000000
VERSION     DAZKPE010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.226"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            104..535
                     /locus_tag="ACG930_003071"
     CDS             104..535
                     /locus_tag="ACG930_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520153.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            537..674
                     /locus_tag="ACG930_003072"
     CDS             537..674
                     /locus_tag="ACG930_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFQ0520154.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            712..>956
                     /locus_tag="ACG930_003073"
     CDS             712..>956
                     /locus_tag="ACG930_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520155.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLV"
BASE COUNT          368 a          135 c          190 g          263 t
ORIGIN      
        1 ctatctattg gcgcagacgg agccattaaa tggagaagaa attcaagtta tggatcagct
       61 tattcatttg ttatcactta ttcaatttaa gggaggaaat ctaatgaaag tagtttacaa
      121 atcaatcaag ccttacggat tcgagcaaat cattttgaac aatcaagaaa atatccctga
      181 aaactgtaca gagattaaac caccagttcc taactggaga ccaagatttg attttgataa
      241 aaaacagtgg gttgagttag ctactgaaga agagaaaaaa gggaatgctg ttgatagcgt
      301 agatgaattg gctaatatta aggcattata cgaaacgctg aaggcagaaa atgatgaatt
      361 gaaacagcta aattctaaag caatgctaaa caatgtagca atcaagcaag aaaatgtctt
      421 attgaaagaa aagtcagaaa gtttagcgca gttgaattca aaaacgatgc ttgcttctgt
      481 acaaaatacc aaggaaatcg aagaaatcaa aaaacaatta caaggtggga agtaacatgt
      541 attcatatga agatatcaaa ctaatgtatg actggggctg tttcactaac gaacaagtaa
      601 tggttttcgt tccgttgtgc attactgaag aagaagcaga taaaatcatt agcaaagaag
      661 agagcgcatc ttaattgatg tgctttttat tttgattcaa ggagttgtca catgattaat
      721 ttaggggaat ggggagcgat agcaggatca ataaccgcta tcgtttcttt gattttatta
      781 gtaataaaac caattactgc atctttctcg aagattactg agactctttc aaaagtaagt
      841 cacaatttag atttgctgac taaagattta gaatcgagca aatcagatcg attgatgatt
      901 catgaagaac taaagaaaca cgatgaaaga ttagatacac atacagaaaa attggt
//
LOCUS       DAZKPE010000214          920 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.229, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000214 DAZKPE010000000
VERSION     DAZKPE010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..920
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.229"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(44..220)
                     /locus_tag="ACG930_003074"
     CDS             complement(44..220)
                     /locus_tag="ACG930_003074"
                     /inference="COORDINATES: protein motif:HMM:NF021542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFQ0520156.1"
                     /translation="MKEFIEKYKYPLIFACVGLLLGLLILTLGLFKIVIITILTVCGF
                     YLGIYLETIGFFDK"
     gene            complement(230..790)
                     /gene="amaP"
                     /locus_tag="ACG930_003075"
     CDS             complement(230..790)
                     /gene="amaP"
                     /locus_tag="ACG930_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFQ0520157.1"
                     /translation="MRKSLKLLLTIVLLLFFFPLAHTLITMQSVVSLPFYLLPFTSYP
                     YIGNNMAQFLFWLSAVLLTFLFIILIIVLFYPRINNYIEKKTDTGKIAIQKKAIENFV
                     LIAAKEEPFIVDPTVKVVIKKKKIKIYVRGKIRKAFQTGERQTSFIRKVNTNLNALFG
                     AEQTILTEIKFNDYHERNKETKSKVL"
BASE COUNT          317 a          136 c          110 g          357 t
ORIGIN      
        1 ataaaaattt attttttacc gtaaaaacgg ttattaacta gttttatttg tcaaaaaatc
       61 caatagtttc taaatagata cctaaataaa aaccacatac agtaagtatt gttattatca
      121 ctattttaaa aagtcctaac gtgagaatta ataatcctaa tagtagtcct acacatgcaa
      181 aaatgagcgg atatttatat ttctctatga attctttcat tgttttctcc tataaaactt
      241 ttgatttggt ttctttattt ctttcatgat aatcattgaa ttttatttca gttagtattg
      301 tttgttctgc accaaataag gcattcaaat tagtgtttac tttccttata aaggaggttt
      361 gtcgctcccc tgtttgaaaa gctttacgta tttttccccg tacatagatt tttatttttt
      421 tcttcttaat tacaactttt accgttggat caacaataaa aggctcttct tttgctgcga
      481 ttaatacaaa attctcaatt gctttttttt gaattgctat ttttccagta tcggtctttt
      541 tttctatata attatttatc ctaggataaa ataatacaat aattaaaata ataaataaga
      601 atgttagcaa aacggcacta agccaaaaca aaaattgagc catgttatta ccaatatatg
      661 ggtaacttgt aaatggtagt aaataaaatg gtaaactaac cacactttgc attgtaatta
      721 acgtatgtgc taaaggaaaa aaaaacagca gtaaaacaat agttaatagt agtttcaagc
      781 tttttcgcat attccacctc ttagattacg ttgtgaatat aattctttat tttattattc
      841 tatggaactt tacaattaaa caaaacctat aaattaaact tgacacagat tttggcagtt
      901 tgatttctag aatattctcc
//
LOCUS       DAZKPE010000215          904 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000215 DAZKPE010000000
VERSION     DAZKPE010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.230"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..582
                     /locus_tag="ACG930_003076"
     CDS             4..582
                     /locus_tag="ACG930_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFQ0520158.1"
                     /translation="MDNKTNNTKTEIKKNDISKASEAIKGELVFEDKVIQKIIGIALD
                     EIDGLLTVDGGFFSNIAGKLVNTDNTTSGVDVEVGKKQVAVDLSIVAEYGKDVTTIYD
                     KIKQVISNEVRKMTGLDVIEINVNVVDVKTKEQYEKDSVTLQDHLTDAASATGEFASK
                     QIEKSKEALGVASEKVNDGVQNVKEATEPRVK"
BASE COUNT          362 a          103 c          153 g          286 t
ORIGIN      
        1 ctaatggata ataaaacaaa caatacaaaa acagaaatta aaaagaatga tatatcaaaa
       61 gcttctgaag ctattaaagg agaattggtt tttgaagata aagtaattca aaaaataatc
      121 ggtattgcat tagatgaaat tgatgggctt ttgacagttg atggaggatt cttttcaaat
      181 atagccggaa aattagtaaa tacagataac acaacttctg gagtcgatgt tgaagtaggt
      241 aaaaaacaag ttgcagtaga tctttcaata gtggctgaat atggtaaaga tgtaactaca
      301 atttatgata aaattaagca agtaatctca aatgaagtta ggaaaatgac tggcttagat
      361 gtaattgaaa ttaacgtaaa cgtcgtagat gtaaaaacaa aagaacaata cgaaaaagat
      421 tcagttaccc tacaagatca tcttactgat gcagcttctg ctactggaga atttgcttca
      481 aaacaaattg agaaatcaaa agaagcttta ggagtagcaa gtgaaaaagt taatgatggt
      541 gtacaaaacg taaaagaagc aacagaacct cgtgtaaaat agtaacttcc tttctgtaat
      601 atacaacata taaaattgaa agactaaatt taaggctctt agatatttta atgtagatat
      661 agaagaaaga actgaaatat aataaaacca gttaggtata ggacttaact ggttttagtt
      721 tctttaagtg ggagatcaac atctgaataa gcattttgtg aaagatgtag aaatctttat
      781 agctgttggt tactcatttt gtatttctta tttagttctt ttgtctcttt ctagtaaatc
      841 tttacaatat tttagttctc aatttatatt atttaaaaat tttattatcg tataaaccat
      901 tata
//
LOCUS       DAZKPE010000216          896 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000216 DAZKPE010000000
VERSION     DAZKPE010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.231"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            256..879
                     /locus_tag="ACG930_003077"
     CDS             256..879
                     /locus_tag="ACG930_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFQ0520159.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          331 a          129 c          166 g          270 t
ORIGIN      
        1 aataaactaa tgtccttatt tttgtgttca catttctgtt acctaagaaa tacttaaagg
       61 aggtgatgta gccagcaacg actacaactt gaacccgcta tctacagttt atttgttgtt
      121 tcttttgggt atactctaat ggtacaaatc catatttgct taaagcgttg atttttcagc
      181 ggtttttctt tattgcaaag tgtaccctaa gacctgtata ctaatagtaa atagattgga
      241 taggaatgat ggcaaatgta tttagcttat ttaagagttt cttccgacga tcaaagttta
      301 gctcggcaac ataagctaat tgaaaattgg tcagtcaaaa ataatattgc tgaagacgat
      361 ttaaaaattt tcgaggaaaa agtctctgga aaaaatattg aaaacagacc agagctgcaa
      421 gagcttattt ctttcatacg tgaacgagat acgattatta ttcctagtct tgatcgatta
      481 gcaagaaata gtaaagatac aaaagactta cttcaattgt ttcgtagtaa aggtgcttct
      541 attgaaatat tagacctacc gtcgtttaat ggggtaactg accctgcatt aagagacttg
      601 ctaacaaatt tagtcataga agtgtttagc tatgttgctg aaaacgaacg gaaaaaaatc
      661 aaagagcgtc aaaaacaagg cattgaaatt gcaaagaaaa atggtcgtta tactggtaaa
      721 aagattcaat accatgccaa tgcaacagga aaaaacaaat tgatttacga tgaaattgtt
      781 gatggtctga agaaaaaaga aactatttct aaaatagcaa agaacgcagg agttacaaga
      841 aaaaccgttt atcgagtaaa aagagattta ggaatgtaat atgttccagt tagaaa
//
LOCUS       DAZKPE010000217          852 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000217 DAZKPE010000000
VERSION     DAZKPE010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.233"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            119..820
                     /locus_tag="ACG930_003078"
     CDS             119..820
                     /locus_tag="ACG930_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFQ0520160.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT          308 a          150 c          145 g          249 t
ORIGIN      
        1 aacaaattat atttgtaaag tattaaaact tgtttctaat gttggtatgt taaaacttta
       61 caaattcttt aaaaaaagtg acaataaata tagtgaacaa taaggagagg actttttaat
      121 gcgtgttaat aaaatcgatt ttcacttttc aaaactcaga tatcaacctg attttgaaca
      181 tttctcggat gaagagttcc aacagatcaa ggaacatact gttcttcgtt cttataaaaa
      241 aggacagatc cttttcgacg atggtgatcc cagacaacgg ttgtatatct tgaccaaagg
      301 actcgttcgt ttagaacgtt atgatgaaag tgcaacttat tactactatg actatgtgaa
      361 tacaaataac ctttttccta tgtcaggaat gtttggagaa gagacctaca cttatacagc
      421 tcaagcgatg actgatattg aaacattcta ccttcctgtt tcctactatg aaaaattagc
      481 acgaaaaaat cccgaacagt tgatctatat gatacaaaaa atttctaaag tagttgaaat
      541 acatgaattg cgtatccaaa tcggattgac ctctagcgcc tttgaccggg taaaacaaaa
      601 tttattcatt ttgaaagaag aattgggcgt accaacaaaa gatggtcata tcaccattcc
      661 ttatccgatc accttaaaag aattagcagt gaatagcggc acgacacgtg aaactgctgg
      721 acaagtaatc aaacaactac gtgattccgg gctgttagat tatgacaaaa agcgttttac
      781 tttctgtaag acagctacta ctccagctat gagagaataa cgcgaacaaa aataagcagt
      841 gaccctgata aa
//
LOCUS       DAZKPE010000218          833 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000218 DAZKPE010000000
VERSION     DAZKPE010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.234"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(20..92)
                     /locus_tag="ACG930_003079"
     tRNA            complement(20..92)
                     /locus_tag="ACG930_003079"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(57..59),aa:His,seq:gtg)
     gene            complement(95..168)
                     /locus_tag="ACG930_003080"
     tRNA            complement(95..168)
                     /locus_tag="ACG930_003080"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(134..136),aa:Trp,seq:cca)
     gene            complement(175..255)
                     /locus_tag="ACG930_003081"
     tRNA            complement(175..255)
                     /locus_tag="ACG930_003081"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(219..221),aa:Tyr,seq:gta)
     gene            complement(257..332)
                     /locus_tag="ACG930_003082"
     tRNA            complement(257..332)
                     /locus_tag="ACG930_003082"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(297..299),aa:Phe,seq:gaa)
     gene            complement(368..440)
                     /locus_tag="ACG930_003083"
     tRNA            complement(368..440)
                     /locus_tag="ACG930_003083"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(405..407),aa:Asp,seq:gtc)
     gene            complement(450..522)
                     /locus_tag="ACG930_003084"
     tRNA            complement(450..522)
                     /locus_tag="ACG930_003084"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(487..489),aa:Val,seq:tac)
     gene            complement(538..609)
                     /locus_tag="ACG930_003085"
     tRNA            complement(538..609)
                     /locus_tag="ACG930_003085"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(574..576),aa:Glu,seq:ttc)
     gene            complement(624..713)
                     /locus_tag="ACG930_003086"
     tRNA            complement(624..713)
                     /locus_tag="ACG930_003086"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(677..679),aa:Ser,seq:gga)
     gene            complement(753..826)
                     /locus_tag="ACG930_003087"
     tRNA            complement(753..826)
                     /locus_tag="ACG930_003087"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(790..792),aa:Asn,seq:gtt)
BASE COUNT          236 a          228 c          189 g          180 t
ORIGIN      
        1 ataccccaag aataaaaagg gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca
       61 atccggtgcg ttaaccactt cgccacattc gccatggcag gggcagcagg aattgaaccc
      121 acactaacgg ttttggagac cgctgttcta cctttaaact atgcccctat aaaatggagg
      181 agagtggatt cgaaccactg aaccctaagg aacggattta cagtccgtcg cgtttagcca
      241 cttcgctact cctccatggt ggcgcgggac agaatcgaac tgccgacaca cggagcttca
      301 atccgttgct ctaccaactg agctaccgcg ccatatttta aaattattaa ttgaataaca
      361 agaacgacgg ttccgacggg aatcgaaccc gcgatctcct gcgtgacagg caggcatgtt
      421 aacccctaca ccacggaacc agttcattat ggaggttaac gggatcgaac cgctgaccct
      481 ctgcttgtaa ggcagatgct ctcccagctg agctaaacct ccaacattca attaaaatga
      541 cccgtacggg attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta accgcttgac
      601 caacgggcca ggtaaatttg ctacggagag taagggattc gaacccttga gacagtttgg
      661 caccatctac atgatttcca atcatgctcc ttcggcctct cggacaactc tccagagtga
      721 aagaagctca atactctttc tcaaaatgag aactccggca gtaggactcg aacctacgac
      781 atcatgatta acagtcatgc gctactacca actgagctat gccggaataa cat
//
LOCUS       DAZKPE010000219          806 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.235, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000219 DAZKPE010000000
VERSION     DAZKPE010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.235"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>806
                     /locus_tag="ACG930_003088"
     CDS             <1..>806
                     /locus_tag="ACG930_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFQ0520161.1"
                     /translation="INGFAYTINNEFNLGPNEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGNVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDDNPTTSEDKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYTFIMDYNTGKELARVRADGIYRPDVNQGYNTSG"
BASE COUNT          278 a          145 c          170 g          213 t
ORIGIN      
        1 attaatgggt ttgcctatac gattaacaat gaatttaatt tagggccaaa cgaaggtagc
       61 tctcaagtag cgaataatca gtatatttta ctgcatgaaa cagctaacga aacagcaaca
      121 ggacgcaatg aagcacagta tatgcaacgt tcatggacta gtgcttacac tgcttacatt
      181 gtgggagacg gcggaaatgt ttatcaagtc ggtcaacctg gttatgtgca gtatggggct
      241 ggttcgtatg ctaatgccaa cagtcccgtg cagattgagt tacaacacac acatgataaa
      301 gcaacgtttg agaaaaacta caaggcatac gttgaattag ctagagattc agcaatgaaa
      361 tatggtattc cattaacatt agacactcct tataaccaac caggaatcaa atcgcattta
      421 tgggtaacac aaaatatttg gggcgatcat acagatcctt acggttatct ttctgaaatg
      481 ggtgtaagta aagaaaaact agcctatgat ttggctcatg gttttacgga tgataatcca
      541 actacttcgg aggataaacc agtaattgat ccaactcgag caggtgctgc aaatcctaca
      601 ctaacagatg gaacaaatta cgcccacatt gatcagtttg gagaaatcga aaacgcaaac
      661 ttgcatgtgg ctggatggca cattgctaac tataaatacg agtatacttt cattatggac
      721 tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag accagatgta
      781 aatcaaggtt ataatacttc tggaaa
//
LOCUS       DAZKPE010000220          787 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000220 DAZKPE010000000
VERSION     DAZKPE010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.236"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..716
                     /locus_tag="ACG930_003089"
     CDS             <1..716
                     /locus_tag="ACG930_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFQ0520162.1"
                     /translation="KKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTST
                     ESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADK
                     SAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWS
                     ESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNE
                     TANNELKNGFNQIVYGQAN"
BASE COUNT          282 a          151 c          159 g          195 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 cttttat
//
LOCUS       DAZKPE010000221          693 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.237, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000221 DAZKPE010000000
VERSION     DAZKPE010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.237"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            132..344
                     /locus_tag="ACG930_003090"
     CDS             132..344
                     /locus_tag="ACG930_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520163.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..>693
                     /locus_tag="ACG930_003091"
     CDS             506..>693
                     /locus_tag="ACG930_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFQ0520164.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVL"
BASE COUNT          247 a          103 c          122 g          221 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct aga
//
LOCUS       DAZKPE010000222          677 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.238, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000222 DAZKPE010000000
VERSION     DAZKPE010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.238"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(276..536)
                     /locus_tag="ACG930_003092"
     CDS             complement(276..536)
                     /locus_tag="ACG930_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520165.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          268 a          102 c           71 g          236 t
ORIGIN      
        1 atcgtgtaat cacctcttga tcttattgta gaaaaagaaa aaccgcgaag caaccacctg
       61 cctaggatta atggttactt acacggttta tattacactc tcatcattaa aaaagtatct
      121 ttcgatatta ctaaacaatg aaattatcta tttgaaattt aaatctgata atatattgag
      181 tgttccaatg agggctttga tcctattatc catatctttt tcagttttaa tattgataca
      241 cattataaga aaaagaaact tttggttaat ttatttcatc ccagtgcaaa atataaaaaa
      301 gtaaaataga ccataggcaa tagattaaca attaatataa tacaagcaaa tattctattc
      361 attgtatttc tgctttcaaa aagttctaat attgaaagta taattccaca aatgcctata
      421 ataagtatgg gaataagatt agaaaataac accccgagcc aatctgtgaa aattactata
      481 tttactaata tccctattaa catacctatc atatttatta aatcaatttt tttcattaga
      541 tatttctcct ttattaaatc tgaagtactt atattaaaat aattctaaac tatttacctc
      601 aaaaagtgca ataaattatt tctgaacaat aaaatgatag tcaaaacaaa aaaatattgt
      661 taatcgttca gagccat
//
LOCUS       DAZKPE010000223          668 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000223 DAZKPE010000000
VERSION     DAZKPE010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.239"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>668
                     /locus_tag="ACG930_003093"
     CDS             <1..>668
                     /locus_tag="ACG930_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFQ0520166.1"
                     /translation="AVKAGFVTEDNLYLDSTHIKANANKHKFTKEMTHDEAKAYQDEL
                     EDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGEREKQFAYSAHTSC
                     DDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLN
                     LRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKE
                     CVNC"
BASE COUNT          226 a          126 c          135 g          181 t
ORIGIN      
        1 agcagttaaa gcaggttttg taacagagga taatttgtat ctggattcta cccacatcaa
       61 agctaacgcc aataaacata agtttacgaa agaaatgacc catgatgaag cgaaagccta
      121 tcaggatgaa ttagaagatg agatcaatcg tcaacgaata gaggctggaa aacgcccttt
      181 tactttggac ttagaaaagg aagtgaagct gaaagaaaga aaaataagta aagctgatcc
      241 ggaaagcggc tactacgtca aaggcgaacg agaaaaacaa tttgcttatt ctgcccatac
      301 ttcatgcgac gacaatggat ttattcttag cacaatcatc actcctggaa atattcatga
      361 cagtcaagtc gcctttcagc tcgtcaaaca atcgaagaga ctttttcctg aaatcaattg
      421 tgttgtcgct gatgctgggt ataagacacc taagtttgtt cactttttga ctcatttgaa
      481 ccttcgacct tgtttgcctt attcaaggcc caaagggaaa aaggggctat tatcaaaaaa
      541 tgagtttctc tatgacgagt attttgattg ttatatttgt ccgcaagatc aaatgctcgc
      601 tttttcaacg gttactcgag aagggtaccg agaatacaaa tccaatccaa aagaatgtgt
      661 gaactgtc
//
LOCUS       DAZKPE010000224          643 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000224 DAZKPE010000000
VERSION     DAZKPE010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.240"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..211
                     /locus_tag="ACG930_003094"
     CDS             <1..211
                     /locus_tag="ACG930_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFQ0520167.1"
                     /translation="LFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFFE
                     NVVTGKENWNDLYHANEVLKIAEEK"
     gene            212..>643
                     /locus_tag="ACG930_003095"
     CDS             212..>643
                     /locus_tag="ACG930_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFQ0520168.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVS"
BASE COUNT          245 a           72 c          118 g          208 t
ORIGIN      
        1 attgtttact ttagatgaat gtatcaatgt tgacttatta aataataaaa taagttttga
       61 agaaaacatt gttaaagaaa tgcctgaatc tgctaatgat atgtatgaga aggagttgaa
      121 atatttcttt gaaaacgtag taacaggcaa agaaaactgg aatgatttat atcatgcaaa
      181 cgaagtattg aaaatagctg aggagaaata aatggaaatt ttatttacta tttgtggtag
      241 agctgggtct aaggggttta aaaataaaaa tttgaaatat ttggcaggaa agcccctagt
      301 ccatttcgct ttagcaatga tagatatcta tcaacaaaaa catcctgaac ataattgcac
      361 gacttgtttg aatacggaca gtaatgagtt agtagaattg acgactaagt taaatccgtc
      421 tgtgaaaatt gtagaacgta aacctgaatt agctacagat actgtaggga aaattgaagt
      481 gatacgtgat tcattcttac aactagaaag agaagataat atatttgatt taattataga
      541 tttagatttg acttcacctt tacgtgaagt ttctaatctt gaagaattaa tagatgaaca
      601 tctaaaaaat ttagataaag acgtctactt ttcagttgtt tct
//
LOCUS       DAZKPE010000225          640 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000225 DAZKPE010000000
VERSION     DAZKPE010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.241"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(113..>640)
                     /locus_tag="ACG930_003096"
     CDS             complement(113..>640)
                     /locus_tag="ACG930_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520169.1"
                     /translation="GLIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLV
                     ELDVNNYRELYVFNSLDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDK
                     CFESAVVKFPQFKLNPAASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIK
                     KAFKIKTIGTAPNFK"
BASE COUNT          208 a           95 c           71 g          266 t
ORIGIN      
        1 ttatgatagt agtcaatttg cttttcacta attacaaaat atgtgatata ggaagtttag
       61 ttattgttct cataatgcca tcctgttttt agattatcta gtaatttttt tgttatttaa
      121 aattaggagc agtgccaatt gttttaattt taaaggcttt ttttatatct tctaaattag
      181 aagatatttg tatatcaata tggaatatat tacctttttt gtattttttt atgttatctt
      241 tagctaaaac atcaaataca tgtccttgaa attgtatcga ggcagctgga tttagtttaa
      301 attgaggaaa ctttaccaca gctgattcaa aacacttgtc acattttttt atttttttac
      361 ctttgtaaaa atattcgatt gaatattcta tttggcacga ctcacttggc agtatatgta
      421 tgtcaatatt tttcatctgt ttcataggta tttcaaaatc taaactatta aaaacatata
      481 attccctgta attatttaca tctaactcta ctaaatttat ctttggaaca atagatcctc
      541 cacccattcc accataataa aaaaaatctt gttctctatc aaaatagcac atattaagct
      601 cagtttgttt atcatcctca ataattttat aaatcaaacc
//
LOCUS       DAZKPE010000226          571 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000226 DAZKPE010000000
VERSION     DAZKPE010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.242"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>571
                     /locus_tag="ACG930_003097"
     CDS             <1..>571
                     /locus_tag="ACG930_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFQ0520170.1"
                     /translation="EENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSAN"
BASE COUNT          212 a          113 c          102 g          144 t
ORIGIN      
        1 agaagaaaat cgagtactct caaaaagctg tcatatagcg attggaataa ccaaagatgg
       61 cgaccgtgaa attatcggct tcatgattca aagtggcgaa agcgaagaga cctggacaac
      121 attttttgaa tacctaaaag aacgcggttt acaaggtacg gaactcgtta tttctgatgc
      181 gcacaaagga ttagtctctg ccattagaaa atccttcacc aacgtaagtt ggcaaagatg
      241 ccaagttcac ttcctaagaa atatctttac caccattcct aaaaaaaatt caaaatcttt
      301 cagagaagct gttaaaggaa tttttaagtt cacagatatt aacttagcgc gtgaggctaa
      361 aaatcgattg attcatgatt atatcgatca accaaaatat tcaaaagctt gcgcatcatt
      421 ggatgatgga ttcgaagacg cctttcaata taccgtacaa ggaaattccc acaatcgact
      481 aaagagtacc aatctaattg aacgactgaa tcaagaagta cgcagaagag aaaagattat
      541 tcgcatcttc cccaatcaaa catcagccaa t
//
LOCUS       DAZKPE010000227          563 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.243, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000227 DAZKPE010000000
VERSION     DAZKPE010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.243"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(29..113)
                     /locus_tag="ACG930_003098"
     tRNA            complement(29..113)
                     /locus_tag="ACG930_003098"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(77..79),aa:Leu,seq:caa)
     gene            complement(131..202)
                     /locus_tag="ACG930_003099"
     tRNA            complement(131..202)
                     /locus_tag="ACG930_003099"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(168..170),aa:Gln,seq:ttg)
     gene            complement(212..284)
                     /locus_tag="ACG930_003100"
     tRNA            complement(212..284)
                     /locus_tag="ACG930_003100"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(249..251),aa:His,seq:gtg)
     gene            complement(346..430)
                     /locus_tag="ACG930_003101"
     tRNA            complement(346..430)
                     /locus_tag="ACG930_003101"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(394..396),aa:Leu,seq:caa)
     gene            complement(451..521)
                     /locus_tag="ACG930_003102"
     tRNA            complement(451..521)
                     /locus_tag="ACG930_003102"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(487..489),aa:Cys,seq:gca)
BASE COUNT          164 a          139 c          127 g          133 t
ORIGIN      
        1 tataagaaag ttgctatatt gataattata ccggcggccg gggtcgaacc ggcacgtcct
       61 caacggacac tggattttga gtccagcgcg tctgccaatt ccgccacgcc ggcaaattta
      121 aaaataataa ctggggtagc tggattcgaa ccaacgcatg agggagtcaa agtcccttgc
      181 cttaccgctt ggctataccc caagaataaa gggcgaatga tgggaatcga acccacgaat
      241 gccggagcca caatccggtg cgttaaccac ttcgccacat tcgccatcat aaaagatgtt
      301 atttaatttc tcaataaaaa actaagatga agacatctta gtcaataccg gcggccgggg
      361 tcgaaccggc acgccctcaa cgggcactgg attttgagtc cagcgcgtct gccaattccg
      421 ccacgccggc aagttgattt attagtacta aggcggtaac cggatttgaa ccggtgatga
      481 aggttttgca gacctctgcc ttaccacttg gctataccgc cattatacta ttatcaatct
      541 ataaaataaa gaataaatta tag
//
LOCUS       DAZKPE010000228          555 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.244, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000228 DAZKPE010000000
VERSION     DAZKPE010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.244"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            24..536
                     /locus_tag="ACG930_003103"
     CDS             24..536
                     /locus_tag="ACG930_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520171.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
BASE COUNT          239 a           49 c           82 g          185 t
ORIGIN      
        1 aagttctaag tttgtgatga taaatgaaat taaatagtat aaatgattta tttgctatta
       61 taggtgttat tgctaacata cttttttcgt gtttgaattt tagatttact caaaagaaca
      121 aaaagaacaa actcagtata gaacaaatga aaaaagacat tgaaactgat ttaaaaaatg
      181 accataaaga aagaagaaaa attgaagaat atacttcttt aatggaaaag tgtaaagcaa
      241 ctgatgcaat ttttagcttt ttaagaaaaa gtgatgagat aatcacacgt gaaaatatag
      301 atttagaaaa tgagattagt aaacttgaat ctatcttttc cgatataaat tctcttaagt
      361 atttaatcgt cgaagaaaat tcggatagct ttttagaatt tgaaaaatat ctaacagatc
      421 ttatagataa tagaaataat gaattaatga gacaaaacat tgcaagattc cttactaaat
      481 tagtttctga atggaaaagt attatttctc aaaatatgga taaattaaga tattaaggat
      541 gttagtttta aaata
//
LOCUS       DAZKPE010000229          550 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.245, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000229 DAZKPE010000000
VERSION     DAZKPE010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.245"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..153)
                     /locus_tag="ACG930_003104"
     CDS             complement(<1..153)
                     /locus_tag="ACG930_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFQ0520172.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
     gene            complement(226..550)
                     /locus_tag="ACG930_003105"
                     /pseudo
     CDS             complement(226..550)
                     /locus_tag="ACG930_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
BASE COUNT          158 a          116 c           86 g          190 t
ORIGIN      
        1 cacccaacga taaatcgtcg tatgagaaac gttaatgcca cgatcatata agatttctcg
       61 aacttcacga tagctaaggt tataacgaag atagtagccc acggctacaa taatcacatc
      121 ctgctgaaat tgctttcctt taaaatgatt catcgtcatt cctcctgcta tctttttcta
      181 ttattctacc ttatttgata gtagatttaa aactttgcaa cagaaccctt caatcactaa
      241 attatagcct tgatcgctta aacggctaat aagtgcttct gtcatgcgat tcgaataagg
      301 ggtaacgtgt tttactacgt ctttttcata gagtttcact aattcgtcaa aatttgggtg
      361 ctgttgttta aaggtatcat tatcaatgac aataacattc ccttgtgttt cttcaaaaat
      421 tgctgatcgc aaactggttt tccctgaccc tggttgccca ccaagtaaaa aagcggttgg
      481 cgattcaacc gctagtctat ttttagttag tcgttcaaca ttcttttcta aacgatcttc
      541 aaattgcttt
//
LOCUS       DAZKPE010000230          550 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.246, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000230 DAZKPE010000000
VERSION     DAZKPE010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.246"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..511
                     /locus_tag="ACG930_003106"
     CDS             <1..511
                     /locus_tag="ACG930_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFQ0520173.1"
                     /translation="INECIEIVDSLTKNISQILSVHSIENLNNDEEYLKINNTLEDIL
                     KKYEILANQKKITVNNYILDENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVND
                     WLYIENSYGNNKISNMDKIFDVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEF
                     FIFKIKIFS"
BASE COUNT          242 a           30 c           80 g          198 t
ORIGIN      
        1 tattaatgaa tgtattgaaa tcgttgatag tttaacaaaa aatatttctc aaatattatc
       61 agttcattct atagaaaatt tgaataatga tgaagaatat ttgaaaataa ataatacatt
      121 agaagacata ttaaaaaagt atgaaatatt agcaaatcaa aagaaaataa ctgtcaataa
      181 ttatatatta gacgagaatg tttatatagg aaaaacagct ttaaagatta ttctatctaa
      241 tttgattagt aatgcggtaa aatatactga tgtaaatggg gtaattaata ttgggatagt
      301 taatgattgg ttatatatag agaattcata cggtaacaat aaaatttcga atatggataa
      361 aatatttgat gttaaatttg atttaaataa ggaaaatagt aatggattag gtttatatat
      421 tgtaagtaat attctgaata attacaatat agaatataaa gtattgcagg atgaagaatt
      481 ttttatcttt aaaataaaaa tattttctta attaagatat aattttgcaa tagttattga
      541 aaaattaggg
//
LOCUS       DAZKPE010000231          542 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.247, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000231 DAZKPE010000000
VERSION     DAZKPE010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.247"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..321
                     /locus_tag="ACG930_003107"
     CDS             127..321
                     /locus_tag="ACG930_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520174.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          229 a           69 c           89 g          155 t
ORIGIN      
        1 ttatatcgag tgaaaaaaac tttcaaattg attcttttta tttatcataa agatatagat
       61 acataatcat tttcacttac atatatttga atattaacta aaaacagcaa gaaagaagag
      121 gatcaaatgt attatgtaga agtaaaaaca aaaggcgtca aaaacaaaca atatgtgaaa
      181 ggtatcagta acgaatatcc tttacttggt tcatggaaag aagctgctcc tttttccaaa
      241 ccatgtgcca taaaaataaa gaacgagcta gaaaaagaac tgacttgtgg taaagctgtt
      301 gtagatatca tcgaaaagta aatccaatgt atagaaagga agatcacaca tgaaaagcga
      361 cgtacaaatt gctaagatta tagaattaga agaagaagac gcagtgttga caattgaaaa
      421 aaaataaatg tttgtatacc atatgattat ttcaatatgt atcctggaat tggagatctc
      481 gtagagctat atcaagatga atcaaatata cttgtcattc atcatgaaat atagagactt
      541 at
//
LOCUS       DAZKPE010000232          541 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.248, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000232 DAZKPE010000000
VERSION     DAZKPE010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.248"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            101..>541
                     /locus_tag="ACG930_003108"
     CDS             101..>541
                     /locus_tag="ACG930_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520175.1"
                     /translation="MISDNKWEINLKRFISEYIYTIETKSSFSLNEDSDPLKKYTIQC
                     KKNKDEKLFVIRPDLMKSNTHYIKEKPKDCDYIIISEANKTVFLIELKSSAQTSPAKE
                     ISEQIDGGYKWLQHLSFLTKYDFTEFSYKIIKVCCKFEARQDRKN"
BASE COUNT          231 a           61 c           84 g          165 t
ORIGIN      
        1 aaatttctaa catcagttat tatgataatt ttgatgatgt caattatgat ttacaggaaa
       61 gatataatga tttaatcgaa gaattagagg agagaggaga atgatttcag ataataaatg
      121 ggaaataaat ctcaaaagat ttatttcaga atatatatat acgattgaaa ctaaatctag
      181 tttttctctt aatgaagaca gtgatcctct aaaaaaatac actattcaat gtaagaaaaa
      241 taaagatgaa aaattgttcg taataagacc agatcttatg aagagtaata cccactatat
      301 aaaagaaaaa cctaaagatt gtgactacat catcataagt gaagcaaata aaacagtatt
      361 tctgatagaa cttaaaagct cagctcagac ttcccctgca aaagaaatta gtgaacaaat
      421 tgatggtgga tataagtggt tacaacatct tagttttcta acaaaatatg attttactga
      481 attcagttat aaaattatta aggtatgttg taaatttgag gcaagacaag atcgtaaaaa
      541 t
//
LOCUS       DAZKPE010000233          536 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.249, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000233 DAZKPE010000000
VERSION     DAZKPE010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.249"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..223)
                     /locus_tag="ACG930_003109"
     tRNA            complement(150..223)
                     /locus_tag="ACG930_003109"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(187..189),aa:Ile,seq:cat)
     gene            complement(413..>536)
                     /locus_tag="ACG930_003110"
     CDS             complement(413..>536)
                     /locus_tag="ACG930_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFQ0520176.1"
                     /translation="NFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          171 a          103 c           98 g          164 t
ORIGIN      
        1 aagtataact atgtgaaaca tcctttcatt aatccataaa aggatacata aaaaagccac
       61 tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa aaaaattcta
      121 acacagaacg attcaaatgg ctacgttaat gtaccctgta ggactcgaac ctacgaccgg
      181 acggttatga gccgtctgct ctgaccaact gagctaaggg tactggttgt tgccacataa
      241 agccataaac aatcaaccag tagaatgtgt ggcaacaaac ctgttatcgc atagcttgga
      301 gtgtgactat ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaataa
      361 tttttatagt tgtcaatata gttatgtact gctcctcaac gaggagctat ttttatcgtt
      421 taggaatatt taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc
      481 cctctggatc attcgttgcc cgcatcatta catagacttt cttactagga aaatta
//
LOCUS       DAZKPE010000234          527 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.250, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000234 DAZKPE010000000
VERSION     DAZKPE010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.250"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          189 a           82 c           84 g          172 t
ORIGIN      
        1 tatatttgaa aagttttact ttgattttta aatagaaaga catttgggtt aaattgtgag
       61 ataataataa agaagagttt aaagcgcacc ccaaaccact tccccataag tgtgttacgc
      121 tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga aaaaaagtga
      181 gaaaaaaggc ttacaattgg agtggtagtt aattagtgac ttatttttga ttttatagca
      241 ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat
      301 atctcctttc acaagtatgg tgataaaatt cgttccgggc taccttttta ggtagcctac
      361 tttaatcttt atacctttct ggatcaacga aagtatactt tatatagtca taacgccgat
      421 gatcgctacg tgcgtccggc acgtcagtca tgaatcggct acactagact agacagaaaa
      481 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatg
//
LOCUS       DAZKPE010000235          520 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.251, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000235 DAZKPE010000000
VERSION     DAZKPE010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.251"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..234
                     /locus_tag="ACG930_003111"
     CDS             <1..234
                     /locus_tag="ACG930_003111"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFQ0520177.1"
                     /translation="ETPVTPENPEPDKPVSLKNTNSKILISEKNVSNTNSKSNNTLPQ
                     TGEKESSGVLAGLVILLASIAVGIKLNLKRKNI"
BASE COUNT          188 a           87 c           64 g          181 t
ORIGIN      
        1 gaaactccag taacgcctga gaaccctgag cctgataaac cagtgtcttt aaaaaacact
       61 aactctaaaa ttttaatatc agagaagaat gtttcaaata ctaattcaaa gtcaaataat
      121 actcttcccc aaactggtga aaaagaatca tcaggagttt tagctggatt agttatttta
      181 ttagcttcta ttgcagtggg tattaaatta aatttaaaac gaaaaaatat ctagattagt
      241 ccaaaagaaa acagagatag aataagtatt catcctatct ctgttttcaa tttaaaataa
      301 ataatcactg ttcgatttaa ttacaaacaa tttccacaat tcctttttta ttttaatatg
      361 cacttcttac ataataaatc ttgattttat caatcttctg cacttcttga tccaccttga
      421 tttgaagtaa cacaaaccga gttatctcat ttgttgtttc ttctccaaat aataaatatt
      481 gatccgattg gattacatct tgtgtgatag tatgaatacg
//
LOCUS       DAZKPE010000236          514 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.252, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000236 DAZKPE010000000
VERSION     DAZKPE010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.252"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACG930_003112"
     CDS             complement(<1..132)
                     /locus_tag="ACG930_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFQ0520178.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAZKPE010000237          512 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.253, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000237 DAZKPE010000000
VERSION     DAZKPE010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.253"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..343
                     /locus_tag="ACG930_003113"
     CDS             <1..343
                     /locus_tag="ACG930_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520179.1"
                     /translation="DNIRDKKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDL
                     IRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRA
                     SLYRKLSEVNN"
BASE COUNT          206 a           69 c           93 g          144 t
ORIGIN      
        1 cgataacata cgagataaaa aggcaagttt aaaatcacta aaagatacat ggcttgattt
       61 atcagaagat aatccataca gccaattctt aattactgta atggctggtg ttaaccaatt
      121 agagcgagat cttattcgga tgagacaacg tgaagggatt gaattggcta agaaagaagg
      181 aaagtttaaa ggtcgattaa agaagtatca taaaaatcac gcaggaatga attatgcggt
      241 aaagctatat aaagaaggaa atatgactgt aaatcaaatt tgtgaaatta ctaatgtatc
      301 tagggcttca ttatacagga aattatcaga agtgaataat tagccattct gtattccgct
      361 aatgggcaat atttttaaag aagaaaagga aactataaaa tattaacagc ctcctagcga
      421 tgccgaaaag ccctttgata aaaaaagaat catcatctta agaaattctt agtcatttat
      481 tatgtaaatg cttataaatt cggccctata at
//
LOCUS       DAZKPE010000238          508 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.254, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000238 DAZKPE010000000
VERSION     DAZKPE010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.254"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          228 a           70 c           81 g          129 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactc
//
LOCUS       DAZKPE010000239          502 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.255, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000239 DAZKPE010000000
VERSION     DAZKPE010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.255"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>502
                     /locus_tag="ACG930_003114"
     rRNA            <1..>502
                     /locus_tag="ACG930_003114"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          119 a          122 c          148 g          113 t
ORIGIN      
        1 gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat
       61 accctggtag tccacgccgt aaacgatgag tgctaagtgt tggagggttt ccgcccttca
      121 gtgctgcagc taacgcatta agcactccgc ctggggagta cgaccgcaag gttgaaactc
      181 aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc
      241 gaagaacctt accaggtctt gacatccttt gaccactcta gagatagagc ttccccttcg
      301 ggggcaaagt gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta
      361 agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attcagttgg gcactctagc
      421 aagactgccg gtgacaaacc ggaggaaggt ggggatgacg tcaaatcatc atgcccctta
      481 tgacctgggc tacacacgtg ct
//
LOCUS       DAZKPE010000240          497 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.256, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000240 DAZKPE010000000
VERSION     DAZKPE010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.256"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          207 a           49 c           72 g          169 t
ORIGIN      
        1 aaaagctgtt aatcaaaaca gttatcatta ttgaaaaatc tttctgattt aatttcagag
       61 gaaaagaaaa tcaatagcgt tattaggaaa tcctagtgac gctattgact tttttataga
      121 tagaagggct aattatttag ttcttttata attgttttaa cacaagaagc tttattgctt
      181 ctattttgtt atttatcaca ctatatcgtg aaatactgta ttttatttgg ttgattgtca
      241 atagatatgg tgtagtagag gaatttagtg aaatggaaga agataaaaaa caataagatt
      301 atctgaaata aaatataatc atagataatc taataaataa agaagcacaa aaagctgaag
      361 aatagaagaa tatagttaat atataactaa ttaatgttca catgtaaaac ctattttcga
      421 aaatacaaaa atataaaaca agatatataa caccagaagt tgaataatgg tattacttgg
      481 aataacagta ccttttt
//
LOCUS       DAZKPE010000241          493 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.257, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000241 DAZKPE010000000
VERSION     DAZKPE010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.257"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..493
                     /locus_tag="ACG930_003115"
     rRNA            <1..493
                     /locus_tag="ACG930_003115"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          120 a          109 c          153 g          111 t
ORIGIN      
        1 ccgcatggaa gggccatcgc tcaacggata aaagctaccc tggggataac aggcttatct
       61 cccccaagag tccacatcga cggggaggtt tggcacctcg atgtcggctc gtcgcatcct
      121 ggggctgtag tcggtcccaa gggttgggct gttcgcccat taaagcggca cgcgagctgg
      181 gttcagaacg tcgtgagaca gttcggtccc tatccgtcgc gggcgttgga aatttgagag
      241 gagctgtcct tagtacgaga ggaccgggat ggacttaccg ctggtgtacc agttgttctg
      301 ccaagggcat tgctgggtag ctatgtaggg aagggataaa cgctgaaagc atctaagtgt
      361 gaagcccacc tcaagatgag atttcccatt tctttaagaa agtaagatcc ctgagagatg
      421 atcaggtaga taggtcagga gtggaagtac agtgatgtat ggagcggact gatactaatc
      481 gatcgaggac tta
//
LOCUS       DAZKPE010000242          492 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.258, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000242 DAZKPE010000000
VERSION     DAZKPE010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.258"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            141..>492
                     /locus_tag="ACG930_003116"
     CDS             141..>492
                     /locus_tag="ACG930_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFQ0520180.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFES"
BASE COUNT          202 a           78 c           65 g          147 t
ORIGIN      
        1 ttacgcagat aaataaatac gttagattaa ttcctaccag tgactaatct tatgactttt
       61 taaacagata actaaaatta caaacaaatc gtttaacttc tgtatttatt tacagatgta
      121 atcacttcag gagtgattac atgaacaaaa atataaaata ttctcaaaac tttttaacga
      181 gtgaaaaagt actcaaccaa ataataaaac aattgaattt aaaagaaacc gataccgttt
      241 acgaaattgg aacaggtaaa gggcatttaa cgacgaaact ggctaaaata agtaaacagg
      301 taacgtctat tgaattagac agtcatctat tcaacttatc gtcagaaaaa ttaaaactga
      361 acattcgtgt cactttaatt caccaagata ttctacagtt tcaattccct aacaaacaga
      421 ggtataaaat tgttgggagt attccttacc atttaagcac acaaattatt aaaaaagtgg
      481 tttttgaaag cc
//
LOCUS       DAZKPE010000243          490 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.259, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000243 DAZKPE010000000
VERSION     DAZKPE010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.259"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>490)
                     /locus_tag="ACG930_003117"
     rRNA            complement(<1..>490)
                     /locus_tag="ACG930_003117"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           98 a          160 c          106 g          126 t
ORIGIN      
        1 cgctacacat ggaattccac tctcctcttc tgcactcaag tctcccagtt tccaatgacc
       61 ctccccggtt gagccggggg ctttcacatc agacttaaga aaccgcctgc gctcgcttta
      121 cgcccaataa atccggacaa cgcttgccac ctacgtatta ccgcggctgc tggcacgtag
      181 ttagccgtgg ctttctggtt agataccgtc aagggatgaa cagttactct catccttgtt
      241 cttctctaac aacagagttt tacgatccga aaaccttctt cactcacgcg gcgttgctcg
      301 gtcagacttt cgtccattgc cgaagattcc ctactgctgc ctcccgtagg agtttgggcc
      361 gtgtctcagt cccaatgtgg ccgatcaccc tctcaggtcg gctatgcatc gtggccttgg
      421 tgagccgtta cctcaccaac tagctaatgc accgcgggtc catccatcag cgacacccga
      481 aagcgccttt
//
LOCUS       DAZKPE010000244          476 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.260, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000244 DAZKPE010000000
VERSION     DAZKPE010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.260"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          181 a           58 c           65 g          172 t
ORIGIN      
        1 atgttaattt atactaaatt aaataaagta ctacctttaa taggtagtac tttattatca
       61 agccattatt ccttcttcta ctagttcttt ttgtcacata attttgcaat caataaatgt
      121 tgtgcaataa gtataagaat tccattttct aaatttgaaa ggtgatccat aatttcatgt
      181 tcaagtagtt tattaattgt ccacttgtcg cttcatctaa aaattttata ggttttagga
      241 atgctattcg cttattttag gaagatttta actgtttgct atagatatat atcatactag
      301 tatcgtaata aaagtactct aaaagaagaa ttttcaaata cgcaaaatta agtacgaaag
      361 agttgaaaca aatttggaga aaatgagcat agaatgtctg atgagttaaa tagacctaaa
      421 aattatctaa aagtggagca aaattaggaa ttacaaacaa aacactaaat tagttt
//
LOCUS       DAZKPE010000245          471 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.261, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000245 DAZKPE010000000
VERSION     DAZKPE010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.261"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            144..401
                     /locus_tag="ACG930_003118"
     CDS             144..401
                     /locus_tag="ACG930_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520181.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          201 a           62 c           66 g          142 t
ORIGIN      
        1 tttttctgtc cacgttcatt ttactccaaa gttttcctca tttcaaaaga aaatcacaga
       61 atacacgaag aagcgtttct atttgtataa actatatcaa agttctatac ttaaattatc
      121 aaataaaaag gacgtgaaga taaatgtcaa atttagaaaa caaagaagaa aaagttgtaa
      181 acaaaattgt ttctgttgtc aataaactgg ataaagagtt agacgaactt gatacgttat
      241 ctgaaaatcc agaaaaaaaa cataacctaa aaaaatggtt agttgaacga aaggctattc
      301 atgaaattaa aaaagttctt catgaagctg ataaatatga aaaatatgat gaaaaagaac
      361 ttgataaaga atttaaagaa atcaatgact tattactata attgatttat acgactcatt
      421 tttgagtcgt cagactgcaa acaacactct aaatttagga gtttgtctac a
//
LOCUS       DAZKPE010000246          462 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.262, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000246 DAZKPE010000000
VERSION     DAZKPE010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.262"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          158 a           63 c           64 g          177 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ct
//
LOCUS       DAZKPE010000247          456 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.263, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000247 DAZKPE010000000
VERSION     DAZKPE010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.263"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..426
                     /locus_tag="ACG930_003119"
     CDS             <1..426
                     /locus_tag="ACG930_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFQ0520182.1"
                     /translation="WHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKV
                     VVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTAS
                     TTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          150 a           87 c           93 g          126 t
ORIGIN      
        1 tggcattatt tgtatcgagc catcgatgca gatggtttaa ccttggatat ttggttacgt
       61 aaaaaacggg acacacaagc agcctatgct tttcttaagc ggttagtgaa gcagtttgat
      121 gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt taagaaacta
      181 aaagaatacg gcttttatca agggacagaa catcgtacca ttaaatacct gaataatttg
      241 attgaacaag accatcgtcc agtaaagaga cgcaataaat tctatcgaag tttacgcact
      301 gcctctacca cgattaaagg catggaagcc attcgaggat tatataagaa aacccgaaaa
      361 gaaggcactc tcttcgggtt ttcggtctgt actgaaatca aggtattatt gggaatccca
      421 gcttaaatca tagataccgt aagggatttt attctt
//
LOCUS       DAZKPE010000248          439 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.264, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000248 DAZKPE010000000
VERSION     DAZKPE010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.264"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..275
                     /locus_tag="ACG930_003120"
     CDS             <1..275
                     /locus_tag="ACG930_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFQ0520183.1"
                     /translation="SITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPIKRRNKFY
                     QSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIKVLMGITA"
BASE COUNT          172 a           74 c           81 g          112 t
ORIGIN      
        1 cctctattac aagtgccttt aagaaactaa aagaatacgg cttttatcaa gggacagaac
       61 atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgacct attaaacgac
      121 gaaataaatt ttatcaaagt ctccgtacag cctcttccac gattaagggc atggagacca
      181 ttcgaggaat atataaaaag aaccgaagaa atggaacgct cttcggcttt tcggtgtcta
      241 ctgaaatcaa ggtattaatg ggaataacag cctaagatat ttggagttca gagagggcgc
      301 gtttgatttt caaacttcgc aacagaacca aagaaggtat caagagtcac agtgaattta
      361 ttccgaaaag tgaaaagagc aaatataaaa tttaataaaa atatagaact aaataggaaa
      421 acgtagacgt aattttcta
//
LOCUS       DAZKPE010000249          435 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.265, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000249 DAZKPE010000000
VERSION     DAZKPE010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.265"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>435)
                     /locus_tag="ACG930_003121"
     CDS             complement(<1..>435)
                     /locus_tag="ACG930_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0520184.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLS
                     YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFK"
BASE COUNT          123 a           76 c           97 g          139 t
ORIGIN      
        1 tttaaacgac tgaggtaacg tagatgaaat tgttttaagg gtttcttgaa agccttccgt
       61 acctcgttta acgaaataat agcgtaataa ttgacaaaaa tgatacgcag ttcgcaattc
      121 ttcgttgtag cttaacagct catcaacgat ttctgtttga ctaattggtc gtttaaacag
      181 tcgatgataa tgccgtttga gtggctccaa tgtcgtggaa tctttgagta agagtttcca
      241 atatcgcttg agccgacggt acttcttctg attttcagag tgtgaggttc gaaaacgatt
      301 catgatctgg acacgtaatt gattgaagct gcgattgatg tgttggacaa tatgaaagcg
      361 gtcagttacg atctccgcat ttggaaagac tgttttaagc aactgacaat agctggcatt
      421 catgtccatc actag
//
LOCUS       DAZKPE010000250          405 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.266, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000250 DAZKPE010000000
VERSION     DAZKPE010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.266"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            63..>405
                     /locus_tag="ACG930_003122"
     CDS             63..>405
                     /locus_tag="ACG930_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFQ0520185.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSG"
BASE COUNT          156 a           75 c           73 g          101 t
ORIGIN      
        1 ataacagtcc ttttacggta caatgttttt aacgacaaaa acatacccag gaggactttt
       61 acatgaccca agtacatttt acactgaaaa gcgaagagat tcaaagcatt attgaatatt
      121 ctgtaaagga tgacgtttct aaaaatattt taacaacggt atttaatcaa ctaatggaaa
      181 atcaacgaac agaatatatt caagcaaaag aatatgaacg aacagaaaac cgacaaagtc
      241 aacgaaatgg ctattatgag cgcagcttta cgacacgtgt aggcacgcta gaattaaaag
      301 tacccagaac acgtgatggc catttttcac ccacagtgtt tgaacgttat caacgaaacg
      361 aaaaagccct catggcttca atgttggaaa tgtatgtatc aggcg
//
LOCUS       DAZKPE010000251          401 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.267, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000251 DAZKPE010000000
VERSION     DAZKPE010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.267"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>401
                     /locus_tag="ACG930_003123"
     rRNA            <1..>401
                     /locus_tag="ACG930_003123"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          123 a           89 c          114 g           75 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc g
//
LOCUS       DAZKPE010000252          392 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.268, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000252 DAZKPE010000000
VERSION     DAZKPE010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.268"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            87..>392
                     /locus_tag="ACG930_003124"
     CDS             87..>392
                     /locus_tag="ACG930_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFQ0520186.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     "
BASE COUNT          159 a           47 c           65 g          121 t
ORIGIN      
        1 aagagggctt ttatatatta atcacaaatc acttatcaca aatcacaagt gattaatcac
       61 aaatcacttg tgatttgtga ttcttaatga tacaatatta ctatacaaaa aaagaatggg
      121 gcgtagttat ggagaaggaa aaactaaaaa tacttgaaga attaagacgt attttaaaca
      181 ataaaaatga agcaattatt atcttgaata attactttaa aggtggtgtt ggaaagtcca
      241 aattatcgac tatgtttgct tacttgacag acaaattgaa tttaaaagtt ttaatgatcg
      301 ataaggactt acaggcaaca ttgacaaaag acttagcaaa aacttttgag gtagaattgc
      361 cacgtgtcaa tttttatgaa ggcttgaaaa at
//
LOCUS       DAZKPE010000253          368 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.269, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000253 DAZKPE010000000
VERSION     DAZKPE010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.269"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>368
                     /locus_tag="ACG930_003125"
     CDS             82..>368
                     /locus_tag="ACG930_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFQ0520187.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCR"
BASE COUNT          130 a           59 c           76 g          103 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcg
//
LOCUS       DAZKPE010000254          362 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.270, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000254 DAZKPE010000000
VERSION     DAZKPE010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.270"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            46..357
                     /locus_tag="ACG930_003126"
     CDS             46..357
                     /locus_tag="ACG930_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0520188.1"
                     /translation="MSKNNNKNNSSELENCLFNPKKLEDSINKVKRINDLPLVLTNKD
                     LKEQFQISDSTLNRLIKLDNFPRCWFGIKGHYLRDDILEWIKKGKEEYFCDQFRLLRE
                     L"
BASE COUNT          151 a           39 c           63 g          109 t
ORIGIN      
        1 gcagctgata gattaatcct taataataga agggaagaga taatcatgtc aaagaataac
       61 aataaaaata attcatcaga gttagaaaat tgtttattta atcccaaaaa gctagaggat
      121 tctatcaata aagtaaagag aataaatgac ctaccgttag ttttaacaaa taaagatcta
      181 aaagaacaat ttcaaataag tgatagtact ttaaatcgtc ttataaaact agataatttt
      241 ccaagatgct ggtttggcat caaagggcat taccttagag atgatatttt ggagtggata
      301 aaaaaaggaa aggaagaata cttttgtgat cagtttcgtt tattacgaga attgtagaat
      361 tt
//
LOCUS       DAZKPE010000255          357 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.271, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000255 DAZKPE010000000
VERSION     DAZKPE010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.271"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>357
                     /locus_tag="ACG930_003127"
     rRNA            <1..>357
                     /locus_tag="ACG930_003127"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           93 a           76 c          110 g           78 t
ORIGIN      
        1 agactcggtg aaattttagt acctgtgaag atgcaggtta cccgcgacag gacggaaaga
       61 ccccatggag ctttactgta gtttgatatt gagtgtctgt accgcatgta caggataggt
      121 aggagccgta gaaatcggaa cgctagtttc gatggaggcg ctggtgggat actacccctg
      181 cgttatggcc actctaaccc gcaccactaa tcgtggtggg agacagtgtc agatgggcag
      241 tttgactggg gcggtcgcct cctaaaaggt aacggaggcg cccaaaggtt ccctcagaat
      301 ggttggaaat cattcgaaga gtgtaaaggc agaagggagc ttgactgcga gaccaac
//
LOCUS       DAZKPE010000256          357 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.272, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000256 DAZKPE010000000
VERSION     DAZKPE010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.272"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..247)
                     /locus_tag="ACG930_003128"
     CDS             complement(<1..247)
                     /locus_tag="ACG930_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520189.1"
                     /translation="MKSKIILGGLLLSTTAFVSLQSPQITSAESLTNSAEIIVPLNLK
                     VKAHYTNGLPLEAGKEVRLRNLTDGSTEVLKKQVDANG"
BASE COUNT          102 a           61 c           52 g          142 t
ORIGIN      
        1 ctccgttagc gtctacctgt ttcttaagta cttccgttga tccatctgtt aaatttctta
       61 accgtacttc ttttcccgct tcaagtggta atccatttgt gtaatgtgct ttcaccttta
      121 aattaagcgg tactataatt tctgctgaat ttgttaaact ttctgcactg gtaatttgtg
      181 gggattgtag tgaaacgaaa gctgttgtag atagtagcaa accgccaaga attatctttg
      241 atttcataat atcattctcc ttaaattcta tttattaagc tcaaaaaata gtttttatgt
      301 taatattcta gctattaaaa ttcttaatac tacaaaagga aaccattgtt ttattga
//
LOCUS       DAZKPE010000257          341 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.273, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000257 DAZKPE010000000
VERSION     DAZKPE010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.273"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          125 a           31 c           49 g          136 t
ORIGIN      
        1 ctatatttta ggtttcatat tatataaatt aataatatac taccatttgt tggtagtata
       61 atttaaaggt aataagttat tcttttatta ctatgtttgg gttttatagc aaggaaagtt
      121 taataagagt ttggatctag caaacaatat taatgaggtc attaaatctt attatcttta
      181 gtgatataac gaaatatcta cacagacaaa attatgatct tgcgtaaagt tataaaatat
      241 caataaaaat attttattaa tgaaaagctt ggtagcacgg ttattcatat gctaatttat
      301 ttcactttat agtaagggga gttcttagta tattgttcaa a
//
LOCUS       DAZKPE010000258          339 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.274, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000258 DAZKPE010000000
VERSION     DAZKPE010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.274"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..239
                     /locus_tag="ACG930_003129"
     CDS             <1..239
                     /locus_tag="ACG930_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HFQ0520190.1"
                     /translation="NAVVESTYKSVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLH
                     GTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          104 a           72 c           77 g           86 t
ORIGIN      
        1 ataatgccgt tgtggaatca acctataaat ctgtcaaagt agaattcgtg catcaatacc
       61 aatttgagac actggcacag ctacgtctag aattgtttga ttatgtgcat tggtggaact
      121 atctacgctt acatggcacg ttggcgtatg aaacaccgat ccaaattcga caacagagat
      181 tggcgaagcg aatccttgat aatgagcgcg gatctgatac ctctggagag gcagcgtaat
      241 tgaatgattg tgcttctgcc ggagaaaatc agatccgagg atgctcattg tcaagggcaa
      301 tcgtagccat aacaccgcag cattcacaac accttataa
//
LOCUS       DAZKPE010000259          338 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.275, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000259 DAZKPE010000000
VERSION     DAZKPE010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.275"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            11..>338
                     /locus_tag="ACG930_003130"
     CDS             11..>338
                     /locus_tag="ACG930_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0520191.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLE"
BASE COUNT          124 a           43 c           68 g          103 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgaga
//
LOCUS       DAZKPE010000260          314 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.276, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000260 DAZKPE010000000
VERSION     DAZKPE010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.276"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(82..>314)
                     /locus_tag="ACG930_003131"
     CDS             complement(82..>314)
                     /locus_tag="ACG930_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0520192.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           99 a           46 c           57 g          112 t
ORIGIN      
        1 aaaaagatgt tggtgaagtt caccaacatc aaaaagtata gagccgatag aaggactgac
       61 cttctgtctc agattttttt gttatttcac ttgaatcaat tgattgatca aaaaaatcct
      121 gattttcatg ttctcaaatg atttaaatcc ataagataat cgtttcagtg tcttgatatg
      181 gggaatcttg gcctctattt tgccattaga atacgggtaa atcatagcat tgtaaatacc
      241 ttcttcatac gttaaaaggt tttgaagttt cgtgcgaagt tgtgcatcaa gtgtttcagg
      301 aagatttttt aata
//
LOCUS       DAZKPE010000261          301 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.277, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000261 DAZKPE010000000
VERSION     DAZKPE010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.277"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>301)
                     /locus_tag="ACG930_003132"
     CDS             complement(<1..>301)
                     /locus_tag="ACG930_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFQ0520193.1"
                     /translation="GDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQR
                     KTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSL"
BASE COUNT           85 a           57 c           51 g          108 t
ORIGIN      
        1 taaagaatat ctcaaagttc cttcaaaacg tcgttgtgct cgacttaata gaacactgta
       61 agccagtaat atgctttcaa atctactctc tagcccttta acagaacgtg agttgaaatt
      121 ttgacaacct aatttttcta aggaagaaaa aacagtctca actgtttttc tttgttttcc
      181 aagtaagctg tggtctagtt tttctgattt atccatgttt ttacgtggcg gaacggatat
      241 agtaatgccc ttaagggcaa gcttttcatg gattttatgg ctaatatatc ctttgtcccc
      301 t
//
LOCUS       DAZKPE010000262          263 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.denovo.279, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000262 DAZKPE010000000
VERSION     DAZKPE010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.denovo.279"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..173
                     /locus_tag="ACG930_003133"
     CDS             <1..173
                     /locus_tag="ACG930_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520194.1"
                     /translation="KGRPKLYSADTKNPQRRLVYENIVKDLNEGVSISKIAKNYNVTR
                     QTIYRIKKDLNL"
BASE COUNT          102 a           39 c           35 g           87 t
ORIGIN      
        1 ataaaggtcg tccaaaactc tatagtgcag atacaaaaaa tcctcaacga cgtttagttt
       61 atgaaaacat cgttaaggac ttgaatgagg gcgtctctat ttcaaagatt gcaaagaatt
      121 ataacgttac tagacaaaca atatatagaa ttaaaaaaga tttgaattta tagatcgtta
      181 cactttctat acaactctct taagtctaat tttggaccat tcatattata aataccatat
      241 tcattaggtt taaaaagatt ttt
//
LOCUS       DAZKPE010000263        10831 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.083, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000263 DAZKPE010000000
VERSION     DAZKPE010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10831
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.083"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            156..1277
                     /locus_tag="ACG930_003134"
     CDS             156..1277
                     /locus_tag="ACG930_003134"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFQ0520195.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            1535..3037
                     /gene="eat(A)"
                     /locus_tag="ACG930_003135"
     CDS             1535..3037
                     /gene="eat(A)"
                     /locus_tag="ACG930_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFQ0520196.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            3104..3631
                     /locus_tag="ACG930_003136"
     CDS             3104..3631
                     /locus_tag="ACG930_003136"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFQ0520197.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            3842..4903
                     /locus_tag="ACG930_003137"
     CDS             3842..4903
                     /locus_tag="ACG930_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFQ0520198.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4906..5802
                     /gene="murQ"
                     /locus_tag="ACG930_003138"
     CDS             4906..5802
                     /gene="murQ"
                     /locus_tag="ACG930_003138"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFQ0520199.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            5816..7798
                     /locus_tag="ACG930_003139"
     CDS             5816..7798
                     /locus_tag="ACG930_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFQ0520200.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(7863..8309)
                     /gene="nrdI"
                     /locus_tag="ACG930_003140"
     CDS             complement(7863..8309)
                     /gene="nrdI"
                     /locus_tag="ACG930_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFQ0520201.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            8520..9944
                     /locus_tag="ACG930_003141"
     CDS             8520..9944
                     /locus_tag="ACG930_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFQ0520202.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(10125..>10831)
                     /locus_tag="ACG930_003142"
     CDS             complement(10125..>10831)
                     /locus_tag="ACG930_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFQ0520203.1"
                     /translation="LLVVLLIGTALLAKKYTTIIDPVEMTAQLFSATSWIVFIMIAAA
                     STIISMEAQYGTLKNLLYRKYSRGEILVSKWITLVIYSVYLYLLAIIVTVLMKLILFP
                     SISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSLVLMIACFINSSGASISAGIVFYF
                     ASSIISGILIALIQKWEWIKWNPISMLNLQNQIGNEEIMKQLTHLSTNQMLFGNLAYI
                     VLFLALGYLVFKRKNV"
BASE COUNT         3503 a         1881 c         2403 g         3044 t
ORIGIN      
        1 tgctccggcc ccagctattg cgattttcat gttttttctc tcctttattc aatgagttcc
       61 cttttagtat atagaaaaat ggaagaaaat agcattgttt tgtttgaaaa aaatgaaaaa
      121 aagtgtctta cttaagaaga aagtgaggga tacagatgga tattttggcg gcaattgatt
      181 catttaaagg aagtgcttct tcatttgaac taaatcaggc agttctaaat ggctgggaag
      241 atcgtaaagg aagaaaaatc aatgtgccga ttgcagatgg cggagaaaat actgcagaag
      301 caatctatta cgcgctcagg ggaacatggc gtaccattga tgggatggat ctcttattcc
      361 gtcagcgaaa aatcagctat ttattgacaa cttggcaagg aaaaaacacc gcagtcatcg
      421 aatctgcaca agcattgggg ttagatctac ttgataaacc aacggatcaa actatccgac
      481 ttgcttccag ttatgcctta ggagaactta ttaaagatgc actgcttcaa gaagtagaac
      541 aaattattgt cactttagga ggaagcgggt gtagcgatgg tggtctagga ttactccaat
      601 ccttgggtgc ttctttagaa gggtacacag aaggaaatcc tttattatct actaaaaaac
      661 ttcattttga tcgaagaaac gttcttgttt ctaaagtaaa attgattatc gctgcagatg
      721 ttaccaatcc atatacaggt caacaaggag ctgcttggca atttggaaga caaaaaggag
      781 gaatagatac gacgctagct ttcttagata aacaagcagg aaagattgct cagcaaataa
      841 aagatttctg ggaggtggat ttagatgata ttccaggaag tggagcagca ggcggtattg
      901 gtggagccct ttttttgttg ggagcgaaga tggtttctgg tttcgattta gtcagccaaa
      961 tcactggatt ggaaaaaaag atcgaacaag cagatgtcat cattacagga gaagggcgga
     1021 tcgatcagca aacgatccac ggaaaagttc catacggtgt agcagtgctt gcaaaaaaat
     1081 atcgaaaacc aataatcgct atttgcggaa gtagagacca agagctagaa ggactttctg
     1141 attttctccc aattgtctta agtattcatt tgggtccaat aggtttagaa gaagcaatgg
     1201 aacacaggca aacattagaa aaaacaaaaa tcttaggaca gacacttagc agatttttca
     1261 ccatcctccc gaagtagttg acaaaatcat tttctttatg ctatcgtaat ttcaaatata
     1321 ggacaaagtg agggatccgt gcattgaaaa attaagtcga ttgatgaaag ctgcattcag
     1381 actgtacctt gtggagacaa ggaagcagtg tgcagatttt cgggattggc ttggtttttt
     1441 cgatgtatgg gtctttttgt gtgtatccaa cccttgcatc ctctttagcc agttctgaaa
     1501 ataggactgg tcttttttta cgaggtgatg gaaaatgtct aaaatcgaaa taaaaaatct
     1561 gacattcggc tacgacagcc aaggcacatt attatttgaa caagcaaatc taaattttga
     1621 cacacaatgg aaactaggac ttatcggacg aaacggtcga ggaaagacaa ctttactgaa
     1681 tattctacaa aacaaactac cttatcaagg gcaagtaatc catcagcaag aatttgccta
     1741 tttcccgcaa cagacaaaag ataaagaacg tttaacctat tacgtgttaa atgatattac
     1801 ggattttgag atatgggaaa tcgaaagaga gctccaattg atgcaaacag atcctgaaat
     1861 cttatggaga gaattcagca cactatcggg gggagagaag acaaaagtcc tactggcact
     1921 tttatttgtg gatgacactc atttcccgtt aatcgatgaa ccaacgaatc atttggatat
     1981 ctctggtaga aaacaagtag cggcttattt gaaaaagaaa aaacaaggct tcatcgtggt
     2041 cagccatgac cggggattta tcgatgaagt agtggaccat gttttagcaa tcgaaaaaag
     2101 tcaactggaa ctttatcaag ggaatttctc tatctatgaa gaacagaaaa aacttcgtga
     2161 tgaatttgaa atggctcaaa atgaaaaatt gaaaaaagaa gtcagtaggc taaagaaaac
     2221 agcagctgaa aaagccgaat ggtctcgttc ccgagaagga gataaaacaa agaaacaagt
     2281 cggattcatc gatactgaat ctagacgagt gaataaagga gcagtgggtg ctgatgctgc
     2341 acggacgatg aaacgatcca aagcaatcgt gaatcggatg gagacccaga tcagcgagaa
     2401 agaaaaacta ttaaaagata tcgaatatat cgattctttg acgatgaata gccaagcgtc
     2461 tcaccataag cgacttttaa gcgtagaaga tcttcaatta gggtatgaaa atctgttatt
     2521 cgagccaatt cattttacaa tcgagcctca tcagcgggtg gcgatttcag gtcctaacgg
     2581 tgcaggaaag tcatccatta tccattatct tctgggggca ttcaacggca aggttatagg
     2641 agaaaaatac cagccaaaac atctgagcat tagttatgca agccaaaatt atgaagacaa
     2701 tcgaggaacg ttggcggaat ttgcagagaa aaaccaagta gactaccaag catttttgaa
     2761 caacctccga aagcttggga tggaaagaga tgtttttcat aacaagatcg agcagatgag
     2821 tatgggccaa cggaaaaaag tggaattggc taaatcttta tcacagccag ctgaactata
     2881 tacatgggat gaaccattga attatttgga tgtcttcaat caagaacaat tagaacaact
     2941 gatcttgaac gtgaaacctg ccatgttact agtggaacat gatcaaacct tcctggataa
     3001 agtatctact gagattattt ctcttgagag aatctaaccc ttgtaatctc aagaacaaca
     3061 aggtatggtt aaggggaact ttgccaacga aggagagaat cacatgcttt atgtaacgag
     3121 acacggagaa acaacttgga acgcacaagg attagtttgc ggacgggcag atgtgccgct
     3181 gactgaaaaa ggacagatgc aggcacagaa actagcagaa aaggtagtag atttgcctgt
     3241 tccaatcacg aaaatcatcc attcccctct tcaacgagca agagatacag cacaagcagt
     3301 tgctgatcgt ctcagcttgc cgctgaccgt tgatgaacga ttggtagaaa tggattttgg
     3361 ggattatgat ggactgccaa gcaaagatga gaactttcaa aaagcacgtt tagcgttcgc
     3421 tgtacgattc ccaaatgggg agtcagtctt agatgtgtat gcacggatcg ttcctttatt
     3481 gaaagaatgc atcgaagacg aagaaaatgt ctatctgtta gtttgccata atgccttgat
     3541 aagagtgatc aatgcttatt ttcatccgat gcctaatgag gggttcttta cattcatggt
     3601 agataataca gaattggttt cttatgagta attatgtttt tgtgttattt aaataaaata
     3661 tttcaaggca ctgcttttgc ttagcagtgc cttttttagg ttatgacaat tcttttgata
     3721 atataaactc aacctttaga aatgaaattt aattatttta ataaaagtat tgaaattttg
     3781 tttctttaga tatatactct agtcatagaa atgaagacgg atacagaaaa agagggataa
     3841 tatgtttggc ttttcaatat ttatgaacga ttctttgtca gaagagaaga aacagtatat
     3901 ccgccaaatg gcatccaatg gctttgtcgg tattttcact tccatgcata taccagaaga
     3961 tgatgtttcg gcatatcaaa agcgattgat cgaactagga agcgaagcga aaaagaataa
     4021 actagaattg atggtcgata tttcaggaga ggcattggaa cgagcgggtt tttcattaga
     4081 agatctaacg cctttgaaag caattggtgt aacaggttta agaatggatt atcatatttc
     4141 caatcagcag attgccgact ggtcacatca attgaaaatc agtttgaatg ctagcacgat
     4201 cacgcctaaa gatatcgatg aattgaaaga agcagaagct gatttctcac agattgaagc
     4261 ttggcataat tattatccac gtcccgaaac agggctggac aaagaatggt atcagaaaaa
     4321 aaatcaatgg ctcaaaattc aaggtctcct tgtccaaggt tttgtaccag gagatacaga
     4381 gttgagaggc ccactatatc aaggattgcc aactttggaa gaacatcgag ggatccatcc
     4441 tcttgcaggc gctctagatc tattagcaag taacacggat attgtttaca tcggagatgc
     4501 aggtctgtca gaaaacgttc aggagcaatt tgcttctttc caaaaagaac agacagtctt
     4561 gctccatacg gaacctgtag atgaagaatt ttacgaatat atattaggga agcatacgaa
     4621 tcggcaagac gatgcaagag atgtcatacg aagcgtagat gcacgttttc gagagattcc
     4681 gcctatccca gcaagaaata cagctacgcg tatgaaaggg tctattactt tagataacga
     4741 aaagtatttg cgctatatgg gtgagatcca attaaccaaa tatgatttgc cagcggatga
     4801 aaaagtgaat gtagtagcta aagttatcaa agaagagcta ccattgatca accaaatcaa
     4861 agctggtatg aactatcaat ttataagaaa agaaggaaga taaaaatgag caaaatcaat
     4921 ttagagaacc taacaacgga acgcagaaac caagaaactt ttggattaga tgagatgagt
     4981 atttctcaag ccgttcaact aatgaacaaa gaagatcaga aagtggccgc tgcggttgaa
     5041 aaagaactga caagtatcga accagtgatt gctaacacga ttgagtcctt taaaaaaggt
     5101 ggacgtctga tttatatggg agccggaaca agtggaagac taggtgtgtt agatgctgct
     5161 gaatgcgtac cgacattcgg tgtagaaccg gaaatggtca taggtctaat tgctggtgga
     5221 gaagaagcaa tgactgtagc tgtcgaaggg gccgaagatt cttatgagct agggcaagaa
     5281 gatctaatca agctgaattt gacaaaaaat gatatagtta ttggtatcgc agctagcggt
     5341 cgtacaccat atgtgatcgg tggattagat tacgcaaaat cgatcggtgc tgtcacagga
     5401 acgatttctt gcaataaaca agccgaaatc agtaaacacg cggatttccc aatcgaagtc
     5461 gatgcaggtc cagaattttt gacaggctct actcgattga agtcaggaac agcacaaaaa
     5521 cttatcttga atatgatttc tactatcagt atgattggta taggtaaagt attcaataac
     5581 ttgatggtcg atgtcaaacc aacaaatgaa aaactaatcg aacgctcaaa acgaatcatc
     5641 atgcaagcga cagaagctga ttacgaaaca gctgaaaagt actttgaaga agcagatcaa
     5701 aatgttaagc tggctatcgt catgattttg acaaatagtg ataaagagga agctcaagca
     5761 aaattagctg aagcaaacgg atttgtaaaa gggaccttat gagggggaaa agaccatggc
     5821 aaaaaacgaa ctgactttgg aagaactggc aaaacaaatt tataaagggg caggcggcat
     5881 gggcaatgta gaaagcattg tccactgcat gactcgtgtg cgtatgaaga tcatcaatga
     5941 tgatcttgta aatgtctctg aattaaaagc gattccagga gtgcttggtg tagtagaaga
     6001 tgaacagctt caagtcatca tcggacctgg gaaagtgaac aaagtagcac agcaaatggt
     6061 tgatttggca ggcgtgaaat taggagaaaa actttcttct gtaagtacag ctacagcaaa
     6121 ttcatcagca tctggaaaag accgtgtaaa cgaacgggca caagaaatga aagcggcaca
     6181 aaaatcgaaa caaaaaccat ctaaaatcaa atcggtatta aaagacattt ctaatatctt
     6241 tgtgccaatg attcctgcat ttgtcggtac tgggatcgtg gcagggattg ccgcagtttt
     6301 agcaaactta gtcacagccg gaacacttga tgcagcaaca tggcaacaat atatcgatgt
     6361 gatgaacatc ttgaaaaacg ggatgtttag ctacctagtt atctatacag gtatcaatgc
     6421 tgcacaagtt tttggtgcaa caccaactct tggtggagtt atcggggccg ttgtgatgct
     6481 gacagggatg aatccggaag caccactgaa aaacttattt actggtgaag ctcttgcagc
     6541 tggacaaggt gggatcctag gtgtcatctt cgctgtttgg ctattgtcaa tcgttgagaa
     6601 aaaactgcat aaagtagtac ctgatgcggt agatatcatc gttacaccaa ctctttcatt
     6661 gattgccatc ggtctgattg aaattttctt catcatgcct ttagcaggtt tcatttctga
     6721 tggcatggtc ggtgggatca actgggtact tggcgttggt ggagcatttg ccggcttcgt
     6781 tctaggcaca ttattcttgc cgatggttat gttcggactg catcaaattt tgactccaat
     6841 ccatgtgcaa atgattgatg aaactggtcg tacgctattg cttccaattc ttgcgatggc
     6901 tggtgcagga caagtgggtg cagcattggc attatggatt cgctgcaaaa aagataaaga
     6961 attaacagaa atgatcaaag gagctttacc agtcgggatc ctaggaatcg gcgaaccatt
     7021 gatttacgga gtaacattac ctctaggacg cccatttatt actgcttgta tcggtggagg
     7081 tatcggcggg gcagtgatcg gaatgatcgg aaatgtcggg gctatcgcta ttggaccttc
     7141 aggagccgct ttgatcccat tgatctctga cggtaaatgg ttaggctaca tccttggatt
     7201 attggcagct tatgctggtg gcttcgttgc tacattcttc ttcggtattc ctaaagaccg
     7261 tttagaaaaa gaagaattag cgactgaaac agccacagta aatgaagtgc ctgaaaaagt
     7321 agtacctcaa acttcagctg aaagtgtgac tatcctctca tcagttgctg acggaacagt
     7381 tgtttcttta gataaagcaa gtgatccagt ttttgcacaa aagatgatgg gtgaaggcta
     7441 ctttgtagaa ccagaaaacg gacatatcta ttctccagtt actggggtag tcagctctgt
     7501 cttcccaacg aaacacgcta ttgggatcac aacgccaaat ggtttagaaa tcttgcttca
     7561 tatgggaatc aacacagttg acttaggcgg tacgccattt gatgtgaaag taacagaagg
     7621 gcagcaagtg acacctgata cgcttgtagc agaagctgac ttagaagcga tcaaagcagc
     7681 aggcaaagaa acatccatga tcgtcttggt aaccaatatg gatcgtgtaa aaaactttgt
     7741 cttggaaaaa acaggtaaag caaaagcaaa agcacctgtg atggatgtca aagcttaata
     7801 tgatagaaac aatagaaacg aaagaagaaa ctgaaatcta tttttcagct tcttcttttt
     7861 tattatttat tgttttctgc taaaatctga taaattcgtg tcacatcaga tggtgttccc
     7921 cgtaattcat aatctgccaa gaaaggaaag ccaaatgttt gtgcatattg tttggctgtt
     7981 agacaatact gattattgaa gtttttattt ccgctaccga ctacaccaag acaaagttta
     8041 tgattgtctt catgttccag atattcacgc atcgtttcgg tcaagatttc tgtatcaccg
     8101 ttatctaaac catttccgcc gtctaaataa gtaggaacga aagtaaaaaa tggttctgtt
     8161 tctttcgtaa aatcactatt ttcatggatt tcttttaaag taacttcagg attgacagga
     8221 tcttctgcat gcattttttc agcatattct gctagatgtt tggcaaaggc acgcgtattt
     8281 cctgaaatcg atatatataa aatgttcatg gatcatcctc caattctttc cttttagtat
     8341 agcatctttt ttaagttttt tggtggtgta atttggaaag ggactaggcg ctttgcttgt
     8401 ataatgagaa aaaagccggt agaattatat ttctattaaa gtttttatta attaagtaaa
     8461 aataaaaaag gtttgttata ctttttgata aaagcggttt tattttggag gatgcttaca
     8521 tggatacaga gcaacagaaa aaaggaattg gtttaattcc acttgctgcc ttagtaattg
     8581 gttcagcgat tggaggtggc gtatttggta ttatgacgga catctccgga tcggctggcg
     8641 gcccagctat tttcagttgg gtactcgtag gaacagcaat gttgatgctc tccttgtcga
     8701 tcaataatat caataaaaaa cgtccagatt taaaaggcgg gatctttagt tacgcagaag
     8761 aaggttttgg ccgtttcgct ggttttatca gcggttgggg ttactggctc acatgctggt
     8821 taggcaacgt agcttttgca acattgttga tgagcgcatt aggatatttc ttcccagtat
     8881 ttgaaggtgg gcaaaatctg gcatcgatcg tgatgagtac agtcttttta tggggatatg
     8941 catggctagt gaatcgggga gtcgaaaatg ctagtttcgt caatgctatc gtcacattct
     9001 gtaaattagt gccattattt ttatttattg tagtagctat cagcacgttt tcgatccaac
     9061 aattcattga taacttttct agcgacatta tattgaatgc gaatggacag ccgatcccgt
     9121 tttccagtca agtattgagt tgcatcatgg tgatgctttg ggtatttgtt ggtattgaag
     9181 gagcctctgt cgtaggttca cgagcaaaaa aacaatcaga tgttgggaaa gcaacgattc
     9241 tagggatatt cggcttgatt attatttacg tcttggtttc catgcttcca tatgggacaa
     9301 tgacgatgaa tcagctgcaa acgatcaagg cgcagcctgc tatgggctat gtgtttgaaa
     9361 tgatggttgg taaatgggga gcagtcgtga tcaacggcgg tttgatcatt tctttagttg
     9421 gtgtttggct ctcatggacg atcttaccga ttgaaacaat gggaaacatg gctgaagacg
     9481 gacttttgcc taaagcatgg ggaaaactca acaaaaatgg ggcaccaact tatgctatcg
     9541 tattgacgac gttatgtacg aatgtctttt tactttcatt attattcact gacagtgctt
     9601 ataactttgc ttacacactt ggtacagcag ctattttctt cacgtggctt ttcttaggat
     9661 tgtaccaaat gaaactttct tatcagcgga aagaatgggt ccaattttta gtagggcttt
     9721 tagcaagtgc ctttcaagta tgggctatgc tagtcgtagc ctttaatgaa gtaatgcttg
     9781 ttcttgttct tttcttgcca ggcatttatt tttacctcaa agcacgtaag gagcaaaacg
     9841 agcctgtaca acatatccac ttagataaga ttttacttat aggtgtgacg atggtcggag
     9901 tgattgcaat ggttttattt gccactggga tgcttcacgt atagaagtat aaaagaagta
     9961 taaagagagg ttgtgagcct gtcgtttatt caaaaacata ctaggaaagg agctgtgaca
    10021 caaatgttgt cacagctcct ttttcagaat aaacggtgtt taagagacag ccaatcggca
    10081 ataaggctga acgtctcttt cacagcctct tttttgatga gtcatcatac attttttcgc
    10141 ttaaatacga gatatcctaa tgctaagaac aaaacgatgt aagctaaatt accgaatagc
    10201 atttgattag tagaaagatg agtcaattgc ttcatgatct cttcgtttcc aatttggttt
    10261 tgcagattca acatactgat cggattccat ttgatccact cccatttttg gatgagtgca
    10321 ataaggatac cagatatgat tgacgaagca aaataaaaga cgattcctgc tgagatggat
    10381 gcgccggaac tattgataaa gcaagcaatc atcaacacta aacttaaaat cagccataaa
    10441 ccgatataac tacccaaagt ataagtgaac aagctttgga tcagtgtttg accagtagaa
    10501 accttctccg tgaaggaaat cgaagggaaa agaatcagtt tcatcaacac agtgacaata
    10561 atagctaaaa ggtataaata aacagaataa ataactaatg tgatccattt gcttactaat
    10621 atttctcctc gagaatactt tcgataaagg agatttttca atgtaccata ttgtgcttcc
    10681 atcgaaatga tcgtgcttgc agctgcaatc atgataaaga caatccaaga tgtggcacta
    10741 aaaagctgag cagtcatttc aactggatca atgatcgtcg tgtatttttt ggctagaagt
    10801 gctgttccta tgagcaaaac aactaataga a
//
LOCUS       DAZKPE010000264         7349 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.103, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000264 DAZKPE010000000
VERSION     DAZKPE010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.103"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            113..1381
                     /locus_tag="ACG930_003143"
     CDS             113..1381
                     /locus_tag="ACG930_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFQ0520204.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            1868..2332
                     /locus_tag="ACG930_003144"
     CDS             1868..2332
                     /locus_tag="ACG930_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFQ0520205.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            2316..2945
                     /locus_tag="ACG930_003145"
     CDS             2316..2945
                     /locus_tag="ACG930_003145"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFQ0520206.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            3299..4777
                     /gene="msr(C)"
                     /locus_tag="ACG930_003146"
     CDS             3299..4777
                     /gene="msr(C)"
                     /locus_tag="ACG930_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFQ0520207.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            4824..5270
                     /locus_tag="ACG930_003147"
     CDS             4824..5270
                     /locus_tag="ACG930_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFQ0520208.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(5469..5984)
                     /locus_tag="ACG930_003148"
     CDS             complement(5469..5984)
                     /locus_tag="ACG930_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFQ0520209.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            6101..7303
                     /locus_tag="ACG930_003149"
     CDS             6101..7303
                     /locus_tag="ACG930_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFQ0520210.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         2323 a         1265 c         1526 g         2235 t
ORIGIN      
        1 caaatttatc aaaaagaaac aaatgttatt taaatatgga cattgacttg cttttacttt
       61 tttagttaca ctgttattta ggaaaagttt cataattcaa aggagaaaaa agatgaaagc
      121 aaagaattta ttatttagcg ttattctttt aggaaatcta gcagttgcca acacaacagt
      181 gctagctgaa gaatcgacag aaactgtcgc aactcagaca tcgagttctt cagaaacagg
      241 aattgaaaac gatacagaga gtactttgca gtcagctact gtctcagaaa atacaatttc
      301 aaccgaagaa ccaacaactg aaacaacaga acaaacacaa accgaagaca gtacatcagc
      361 agaagctcag aacaatccag agaatgcaga agaaatcacg aaccaattga cagatgggca
      421 aacattgaca catacccatc aagcagattt gtctgaattc gaaaactata ctggctatgc
      481 tttttatgct cgctcatctg ctaattctca acaagcgttc attgatagta ttgcctcaac
      541 tgcacaaagt ttggcaagtg ccaatgactt atatgcatca gtcatgattg ctcaagccat
      601 cgttgaaagt ggctggggga acagtacttt ggcttctgcc cctaattaca atctatttgg
      661 gattaaagga agctataatg gccaatctgt tacgatgcct acttcggaat atgtgaatgg
      721 gcaatggatt acggtgaatg ccgcttttag aaaatatcct tcgtacaaag aatcattgca
      781 agataacgta acggtattga agacgacttc ttttcagcca ggcgtttact actattccgg
      841 tgcatggaaa agcaatacga actcttacaa agatgctacg gcttggctaa caggtcgtta
      901 tgccactgcg cctaattatg gttctacatt gaacaatgta atcgaaacct ataatctgac
      961 acagtatgat acagcaccaa cttcaacttc tccgatgtat cgtctgtata accgtcatac
     1021 aggagaacat ttatatacat tgaatgccgg agaaaaaaat tatctgccaa ctgtaggctg
     1081 ggaatatgaa gggattgctt ggcaagcacc aaacagcgga caacctgtct accgtttata
     1141 caatccttac agtggagacc atcattacac aatggcacaa tctgagatca actctttaac
     1201 aaaaatcggt tggcgttatg aaggtctaag tttttattct ggtggttcca agccaattta
     1261 tcgactattt aatccaaatg aaaaaactgg tacccatcac tataccttga gtgctaagga
     1321 aagagattgg ctaacaccga tgggctggag atatgaagga ataggatttt atggttatta
     1381 aaaagaggta gtgaaaaagc tgccctgcat caagtagtaa gaacagccaa acaaaaacag
     1441 attttcatgt tttttgtttg gttgaactta ttaccgcaga tgcaagtttt tgaacaccgt
     1501 ttactcaaaa aaggttgtga caacatcttg tcataacttt tttattactg tttaagcata
     1561 ctgatccaat ttctaatatt cgacgggatt cttgcaaaag gcgatttcgg aaatttttgg
     1621 cggtgtaaaa ttttctactg cagaagagct atcttctata gtttgataag aatcaataat
     1681 cttggtttta gcgttgtgct ttctttatca ttttttccgt tcattctaca aaaaatttct
     1741 tttctctata cttttctatt gagagcgttt tttttattac acagctgatt ctttgacttt
     1801 tttctttttt tattctatta ttgacaagtc aatcgttgac gagtcaatta ttagaaggga
     1861 ggaaattatg tctttagaag agattagtca ccttttatat caaatcaaat tagccgatca
     1921 aaaaatcgtc cagatctttg aagaaaatat cggtataagt cttactagat acgagatcat
     1981 gatgagactg aaagaagaaa atccattgct acaaagcagt ttgcaagaaa agttgcagat
     2041 tgatcaagga gcagttactc gtcatctgaa ggtattggaa gcaaatggct atgtttcgcg
     2101 tcagagaaat cctcagaaca accgggaagt gtatgtagcg ctaacagaaa aagcccagaa
     2161 gaaaatcgag cattgtgaaa tggaccataa agatacaggt tccgtgctat ccccggcttt
     2221 cagcgatgta gaaatgaaac aatttctaac acttttagat aaattgaata cccaactttg
     2281 caatataaca acagaaacga aagaggttaa taataatgga acaaaaaaat gatttttcaa
     2341 caattatgac tggtagaaga tccgttcgcg tatatgatga aacatacaaa atcccacacg
     2401 aagaaatgct ggaaatgatc aaagaagcga cgactgcacc ttcttctgtc aatatgcaac
     2461 catggcgctt tgtggtcgct gaaagcgagg aagcaaaaga aatcttgcgt cctttgatcc
     2521 gtttcaatac gagacaaaat gatacttctt ctgcaatggt catgattttt ggcgatatgc
     2581 aatgttacga atatggcgaa gaaatctata accaagctta cgaatcaggg aagatgccaa
     2641 aagaagtcag agatcaacaa ttagctgcga tcattcctta ttacaagagt ttttcaagag
     2701 aagaaatgaa cgatgtagtc aaagtcgatt ctagcttagc ggctatgcaa ttcatgttag
     2761 ttgcgcgtga tcatggctat gaaacaaatc caattggtgg agtcgaagca gatcagttgg
     2821 cagaggcatt tggtttggat aaagaccgtt atgttccagt tattatttta tcaataggaa
     2881 aagcggtaga agaaggttac gagtctgttc gtttagcacc agaaaagatc actacgttcg
     2941 aataaaaggt tttcagttac tattcagtag ctattgcttt ttttgaatcg tgtgtggtaa
     3001 cctaataaaa aaggaggtcg gaaaaatgac tgcatcgatg aaattacgtt tcgaactttt
     3061 gaataacaac taaataaatt caaaagacat gtataaacaa caatttcatg gatggagtat
     3121 gtccattttt tcgaacgaca gtagaatagg tgaaagctat gacagatttg gtgatttagt
     3181 catagttatt tcgttcagag taggaaaaga tgtgatgcag tttttttgca aacagatttt
     3241 tctgctcttt tttagtatcg ataattgttg ttttacatga aataggagtg taaaacatat
     3301 ggaaaattta gcagtaaata taacaaatct acaagtcagc tttggcaacc agctagaact
     3361 atctattgat tctcttcgtg tctatcagca agatcgtata gggatcatag gagaaaatgg
     3421 tgtcggtaaa tcgactttgc tcaaactaat agccggtgaa ctttttcccg atcatgggaa
     3481 aatccaaaca gagatcacct tcaactacct gcctcaatta acctatctcg ctgaagcaaa
     3541 ggacctaaat ttggaattag ccagtcattt ccagttaaga ctggaagaaa cttcagagcg
     3601 gaaatggagc ggaggggaag aacgaaagat cgagttgata cgtcttcttt cttcttatga
     3661 acaagggatg cttctagacg agccaacaac ccatctagat agaaaaagta ttgatcgact
     3721 gattgaagag cttcgttatt attatggtac gctggttttt gttagtcatg atcgctattt
     3781 tctagatgag ctagcatcga aaatctggga agtaaaagac ggagaaatcc gagagttttc
     3841 ggggaattat agtgcctatc tcactcaaaa ggaattggag aaaaagactc agctacgaga
     3901 agcagagtcg atcatgaaag agaaaaaacg attggaaaaa tcgatccaag aaaagaaaaa
     3961 acaagcggaa aagttggaaa aagtgtccag taaaaagaaa aagcaacaaa tcagaccgga
     4021 tcggttgtct tcctctaaac aaaaagacag tgtacaaaaa gccatccaaa agaatgcgaa
     4081 aacattagag agaagactcc aaaaaatagg agaaacaacc aagccgcagc agatgaaaca
     4141 aatccgtttt ccagtaccaa aatctcttga actccacagc cgctatccca tcatgggaca
     4201 aaatgtccaa ttggaaagaa gtgggagaac attactggta aatggtgatt ttcagttttc
     4261 tttaggtaaa aaaatcgcga ttgtcggtga aaatggttca ggtaagacaa ccttattaga
     4321 acatatccgc aaacaaggag aaggaatcct tctctctccg aaagtaagct ttcaagtata
     4381 tcagcaaaag ggttatcaaa tgacatctga agaatccatc attcgttttg tcatgagaca
     4441 aacagagttt tcagaatcgc ttgtccgtag tttgctgaat cacttagggt ttgctcagga
     4501 aactttgacg aaaccgttat gtacattaag tgggggagaa gcgacccgtc tgacgattgc
     4561 tttgcttttt actaagccaa gtaatgtgtt gctgttagat gaaccgacta attttattga
     4621 tatggcaacg atcgaagctt tagagaagct aatgcaaata tatccgggaa cgattttgtt
     4681 tacttctcat gattcttact ttgtcgagcg tacggctgat gaagtttatg aaataaaagg
     4741 gcagaaaata aaaaaagtac ttacgagaaa tttttaaatg tgctacgatg attttcgtga
     4801 caaatttaaa ggagtggtac agattgccta caaataaaaa agaaggaata atttttacaa
     4861 caatgatgtg ttttttgatg gtcttgggga tgagcgcgta taatttatgg ctgcatcaag
     4921 atcttcattt atcaagtttg ttgattggtc tagtgcctgg attcgtggtg gctttcattt
     4981 tggatgtctt catcatcggt gtgctggcga aaaaaattgc ctttaaacta ccagtaaatc
     5041 cagaaagcaa ggtccaaatg atcttaacta tttcatgctt gatggtttta ggaatggtga
     5101 catgtatgtc tttattcggt gtgatcatgg aacaaggaat acctgatcaa ttattctctg
     5161 cttatatgaa tgcttggaaa atgaatgtga ttgccgcttt accgttgcag ttgatcatcg
     5221 ttggcccgct ttcaagaagt gtgctaaaag caattcaaag taatgaatga tggaacactg
     5281 ttatttgaaa aaaggccttg gcatgctttt tgtcatagtc tcttgaatgc agttctagaa
     5341 aaatagtgat ccgaacgata ggttttggcc tgtcgttcgg atcgcttttt cttttccaac
     5401 tgtattgctc ttttattgaa gataatttgc tcttcaatag atatttctag aaaggttctg
     5461 tttatccctt actcaaaaaa ctgctgcatt tgttctctta cttgctgaca ccattggagt
     5521 tcctgctgac aaagcataat tctgcgctgg atcacaacat aacgtccaaa ttcttgtttc
     5581 ttgtctagcg agaggtcatt caattttttt tgattttttt gcatgatttt gttcagctgt
     5641 tgttctctag tgaatagcag tccagtagct gttgttttat cgagcgtcga aaaagcatag
     5701 atttttgcta gaaattcatc tttttgcgta ggagcgggag tttcctcttt gatccattcc
     5761 tctacaagag cacgtccttc atcagtcaag tggtagatct ttttttgaga gtgctcgtct
     5821 ttgtccaaaa cggtcacata accctgctgg tctaacttgg caagcgttgt atagatctga
     5881 ctgtgatggg cttcccaaaa aattgtgatc agctgcttca attcataccc agaacgtggt
     5941 ttggataaaa gcacgcataa taatatatag gctaaagtat tcataaaaat cctacctctc
     6001 gtcttatttt ctttattata tcacagtaaa gtttccacgt tttacatgtg catatttaca
     6061 tgtaaaataa atcatgtatg atgctaatag agagaaaggg atggaaatat tggagaatca
     6121 aatagatata caagaacaaa caaatgaaga aacaaagggg aaaagttcag cgctagttgt
     6181 agcagctacc tgtatgatcg cttttatggg agtgggtcta gtagacccaa tcttaaaaac
     6241 gattgctgca cagttaaacg ctacgccagc tgaaacgacc ctgttattta ctagttacat
     6301 gttagtcact ggtgtggtga tgctatttac aggtttctta tctagtcgga tcggtttgaa
     6361 aaaaacattg atgacaggat tgtttatcat cgttgtattc gctggtcttg gcggattatc
     6421 tgggaatatc ggaatgctga ttgggttacg tgccggctgg ggtgtcggga atgctttatt
     6481 tgtctctact gctttagcaa cgatcgtcag tattttagtt ggtaacacag aaaaagcaat
     6541 catgatgtat gaagcagcac ttggctgcgg aatggctgtt ggccctctag tcggtggggt
     6601 cttgggcagt ggttcatggc gttatccatt ttttggggta gcatttttga tgttttgcgg
     6661 ttttatagcc ctagcggtac ttttacctga aactgagaaa ccaaagagaa aagtaggcct
     6721 ttgggaaggt gtcaaagcgt taagcaatca taaacttcgt tcagttggac taatcgcatt
     6781 gttatataat ttcggattct ttactttact tgcgtatgcg ccatttttat tgattggcta
     6841 ttctgaatta gaagtcggtt ttgtattttt tggctggggt gtgcttctgg ctattgcttc
     6901 gattttcgtt gcaccggctc ttgagcggaa gtttacgact tatcggacaa ttttagcagc
     6961 atttgtctta ttcattattt gtttgctgtt attaggagct ggaacttcta tgccagtcct
     7021 tgtaccgatc agcattgtgt tagcaggatt tttccaagga attatcaata cactgttgac
     7081 gacgattgct atggaaatac caggtctgca acgaaacgtt gcttcgtcca gctatagttt
     7141 tgtccgcttt ttcggtggag ctttagcacc atttattgca ggtgtgattg gtgaacatat
     7201 tggtgaaagc tatgcgtttt attttgcagg tgccattgtt cttatcagtg tatgttgtat
     7261 catttatcac cgtaattatt ttgctacaaa tgaagaagaa taagaaatca gaggttgtga
     7321 aaaagctgtc ctgcatcaag tcataagaa
//
LOCUS       DAZKPE010000265         4809 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.128, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000265 DAZKPE010000000
VERSION     DAZKPE010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.128"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            260..1171
                     /locus_tag="ACG930_003150"
     CDS             260..1171
                     /locus_tag="ACG930_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFQ0520211.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG930_003151"
     CDS             1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG930_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFQ0520212.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            2328..2612
                     /locus_tag="ACG930_003152"
     CDS             2328..2612
                     /locus_tag="ACG930_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFQ0520213.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            2978..3277
                     /locus_tag="ACG930_003153"
     CDS             2978..3277
                     /locus_tag="ACG930_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520214.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            3320..>4809
                     /locus_tag="ACG930_003154"
     CDS             3320..>4809
                     /locus_tag="ACG930_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFQ0520215.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
BASE COUNT         1783 a          705 c          887 g         1434 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccc ccattgtcaa caggcagttc
       61 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
      121 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
      181 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
      241 gttaaggagg agactgaaaa tgaagaagtt gtttttttta ttgttattgt tattcttaat
      301 atacttaggt tatgactacg ttaatgaagc actgttttct caggaaaaag tcgaatttca
      361 aaattatgat caaaatccca aagaacattt agaaaatagt gggacttctg aaaataccca
      421 agagaaaaca attacagaag aacaggttta tcaaggaaat ctgctattaa tcaatagtaa
      481 atatcctgtt cgccaagaaa gtgtgaagtc agatatcgtg aatttatcta aacatgacga
      541 attaataaat ggatacgggt tgcttgatag taatatttat atgtcaaaag aaatagcaca
      601 aaaattttca gagatggtca atgatgctgt aaagggtggc gttagtcatt ttattattaa
      661 tagtggctat cgagactttg atgagcaaag tgtgctttac caagaaatgg gggctgagta
      721 tgccttacca gcaggttata gtgagcataa ttcaggttta tcactagatg taggatcaag
      781 cttgacgaaa atggaacgag cccctgaagg aaagtggata gaagaaaatg cttggaaata
      841 cgggttcatt ttacgttatc cagaggacaa aacagagtta acaggaattc aatatgaacc
      901 atggcatatt cgctatgttg gtttaccaca tagtgcgatt atgaaagaaa agaatttcgt
      961 tctcgaggaa tatatggatt acctaaaaga agaaaaaacc atttctgtta gtgtaaatgg
     1021 ggaaaaatat gagatctttt attatcctgt tactaaaaat accaccattc atgtgccgac
     1081 taatcttcgt tatgagatat caggaaacaa tatagacggt gtaattgtga cagtgtttcc
     1141 cggatcaaca catactaatt caaggaggta aggatggcgg aatgaaacca acgaaattaa
     1201 tgaacagcat tattgtacta gcacttttgg ggtaacgtta gctttttaat ttaaaaccca
     1261 cgttaactag gacattgcta tactaatgat acaacttaaa caaaagaatt agaggaaatt
     1321 atattgggaa aaatattatc tagaggattg ctagctttat atttagtgac actaatctgg
     1381 ttagtgttat tcaaattaca atacaatatt ttatcagtat ttaattatca tcaaagaagt
     1441 cttaacttga ctccatttac tgctactggg aatttcagag agatgataga taatgttata
     1501 atctttattc catttggctt gcttttgaat gtcaatttta aagaaatcgg atttttacct
     1561 aagtttgctt ttgtactggt tttaagtctt acttttgaaa taattcaatt tatcttcgct
     1621 attggagcga cagacataac agatgtaatt acaaatactg ttggaggctt tcttggactg
     1681 aaattatatg gtttaagcaa taagcatatg aatcaaaaaa aattagacag agttattatt
     1741 tttgtaggta tacttttgct cgtattattg ctcgtttacc gtacccattt aagaataaat
     1801 tacgtgtaag atgtctaaat caagcaatct gatctttcat acacataaag atattgaatg
     1861 aattggatta gatggaaaac gggatgtggg gaaactcgcc cgtaggtgtg aagtgagggg
     1921 aaaaccggtg ataaagtaaa aagcttacct aacactatag taacaaagaa agcccaatta
     1981 tcaattttag tgctgaggaa ttggtctctt taataaattt ccttaacgtt gtaaatccgc
     2041 attttcctga cggtaccccc actagcagcc atgctttttt tgaatctttg taggacgttt
     2101 taaagagaat tacccacttt aaaattaaac atgcgcttag aatcgcttta ggaaacacga
     2161 tccagtccaa taatcgtcga taaaaacttt tgaaaaaggt tggtgaaatt acctactttt
     2221 ggaataatca caaatcacaa gtgattaatc acttgtttat taagatatta aaagctataa
     2281 tttaaataaa gcgtgaattt tattacacaa aaagaggggg gagaaacttg gaactagcat
     2341 ttagagaaag cttaaaaaag atgagaggta ccaaatcaaa agaaaaattc tcccaagaat
     2401 tagaaatgag tagatcaaat tattcacgaa tagaatcagg aaaatcagat ccaaccataa
     2461 aaacactaga acaaattgca aagttaacta actcaacgct agtagtggat ttaatcccaa
     2521 atgagccaac agaaccagaa ccagaaacag aatcagaaca agtaacattg gatttagaaa
     2581 tggaagaaga aaaaagcaat gacttcgtgt gaataatgca cgaaatcgtt gcttattttt
     2641 tttaaaagcg gtatactaga tataacgaaa caacgaactg aatagaaacg aaaaaagagc
     2701 catgacacat ttataaaatg tttgacgaca ttttataaat gcatagcccg ataagattgc
     2761 caaaccaacg cttatcagtt agtcagatga actcttccct cgtaagaagt tatttaatta
     2821 actttgtttg aagacggtat ataaccgtac tatcattata tagggaaatc agagagtttt
     2881 caagtatcta agctactgaa tttaagaatt gttaagcaat caatcggaaa tcgtttgatt
     2941 gctttttttg tattcattta tagaaggtgg agtttgtatg aatcatgatg aatgtaaaac
     3001 ttatataaaa aatagtttat tggagataag aaaattagca aatatctata cactagaaac
     3061 gtttaagaaa gagttagaaa agagaaatat ctacttagaa acaaaatcag ataagtattt
     3121 ttcttcggag ggggaagatt atatatataa gttaatagaa aataacaaaa taatttattc
     3181 gattagtgga aaaaaattga cttataaagg aaaaaaatct ttttcaaaac atgcaatatt
     3241 gaaacagttg aatgaaaaag caaaccaagt taattaaaca acctatttta taggatttat
     3301 aggaaaggag aacagctgaa tgaatatccc ttttgttgta gaaactgtgc ttcatgacgg
     3361 cttgttaaag tacaaattta aaaatagtaa aattcgctca atcactacca agccaggtaa
     3421 aagcaaaggg gctatttttg cgtatcgctc aaaatcaagc atgattggcg gtcgtggtgt
     3481 tgttctgact tccgaggaag cgattcaaga aaatcaagat acatttacac attggacacc
     3541 caacgtttat cgttatggaa cgtatgcaga cgaaaaccgt tcatacacga aaggacattc
     3601 tgaaaacaat ttaagacaaa tcaatacctt ctttattgat tttgatattc acacggcaaa
     3661 agaaactatt tcagcaagcg atattttaac aaccgctatt gatttaggtt ttatgcctac
     3721 tatgattatc aaatctgata aaggttatca agcatatttt gttttagaaa cgccagtcta
     3781 tgtgacttca aaatcagaat ttaaatctgt caaagcagcc aaaataattt cgcaaaatat
     3841 ccgagaatat tttggaaagt ctttgccagt tgatctaacg tgtaatcatt ttggtattgc
     3901 tcgcatacca agaacggaca atgtagaatt ttttgatcct aattaccgtt attctttcaa
     3961 agaatggcaa gattggtctt tcaaacaaac agataataag ggctttactc gttcaagtct
     4021 aacggtttta agcggtacag aaggcaaaaa acaagtagat gaaccctggt ttaatctctt
     4081 attgcacgaa acgaaatttt caggagaaaa gggtttaata gggcgtaata acgtcatgtt
     4141 taccctctct ttagcctact ttagttcagg ctattcaatc gaaacgtgcg aatataatat
     4201 gtttgagttt aataatcgat tagatcaacc cttagaagaa aaagaagtaa tcaaaattgt
     4261 tagaagtgcc tattcagaaa actatcaagg ggctaatagg gaatacatta ccattctttg
     4321 caaagcttgg gtatcaagtg atttaaccag taaagattta tttgtccgtc aagggtggtt
     4381 taaattcaag aaaaaaagaa gcgaacgtca acgtgttcat ttgtcagaat ggaaagaaga
     4441 tttaatggct tatattagcg aaaaaagcga tgtatacaag ccttatttag tgacgaccaa
     4501 aaaagagatt agagaagtgc taggcattcc tgaacggaca ttagataaat tgctgaaggt
     4561 actgaaggcg aatcaggaaa ttttctttaa gattaaacca ggaagaaatg gtggcattca
     4621 acttgctagt gttaaatcat tgttgctatc gatcattaaa gtaaaaaaag aagaaaaaga
     4681 aagctatata aaggcgctga caaattcttt tgacttagag catacattca ttcaagagac
     4741 tttaaacaag ctagcagaac gccctaaaac ggacacacaa ctcgatttgt ttagctatga
     4801 tacaggctg
//
LOCUS       DAZKPE010000266         4805 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.129, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000266 DAZKPE010000000
VERSION     DAZKPE010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.129"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            92..787
                     /gene="vanR-A"
                     /locus_tag="ACG930_003155"
     CDS             92..787
                     /gene="vanR-A"
                     /locus_tag="ACG930_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFQ0520216.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            765..1919
                     /locus_tag="ACG930_003156"
     CDS             765..1919
                     /locus_tag="ACG930_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFQ0520217.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2134..3102
                     /locus_tag="ACG930_003157"
     CDS             2134..3102
                     /locus_tag="ACG930_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFQ0520218.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3095..4126
                     /gene="vanA"
                     /locus_tag="ACG930_003158"
     CDS             3095..4126
                     /gene="vanA"
                     /locus_tag="ACG930_003158"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFQ0520219.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4132..4740
                     /locus_tag="ACG930_003159"
     CDS             4132..4740
                     /locus_tag="ACG930_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFQ0520220.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1482 a          922 c         1119 g         1282 t
ORIGIN      
        1 catggccttt tatcttttac acaattatat ggactttatc ctataatctg ataaattatt
       61 aagggcaaac ttatgtgaaa gggtgataac tatgagcgat aaaatactta ttgtggatga
      121 tgaacatgaa attgccgatt tggttgaatt atacttaaaa aacgagaatt atacggtttt
      181 caaatactat accgccaaag aagcattgga atgtatagac aagtctgaga ttgaccttgc
      241 catattggac atcatgcttc ccggcacaag cggccttact atctgtcaaa aaataaggga
      301 caagcacacc tatccgatta tcatgctgac cgggaaagat acagaggtag ataaaattac
      361 agggttaaca atcggcgcgg atgattatat aacgaagccc tttcgcccac tggagttaat
      421 tgctcgggta aaggcccagt tgcgccgata caaaaaattc agtggagtaa aggagcagaa
      481 cgaaaatgtt atcgtccact ccggccttgt cattaatgtt aacacccatg agtgttatct
      541 gaacgagaag cagttatccc ttactcccac cgagttttca atactgcgaa tcctctgtga
      601 aaacaagggg aatgtggtta gctccgagct gctatttcat gagatatggg gcgacgaata
      661 tttcagcaag agcaacaaca ccatcaccgt gcatatccgg catttgcgcg aaaaaatgaa
      721 cgacaccatt gataatccga aatatataaa aacggtatgg ggggttggtt ataaaattga
      781 aaaataaaaa aaacgactat tccaaactag aacgaaaact ttacatgtat atcgttgcaa
      841 ttgttgtggt agcaattgta ttcgtgttgt atattcgttc aatgatccga gggaaacttg
      901 gggattggat cttaagtatt ttggaaaaca aatatgactt aaatcacctg gacgcgatga
      961 aattatatca atattccata cggaacaata tagatatctt tatttatgtg gcgattgtca
     1021 ttagtattct tattctatgt cgcgtcatgc tttcaaaatt cgcaaaatac tttgacgaga
     1081 taaataccgg cattgatgta cttattcaga acgaagataa acaaattgag ctttctgcgg
     1141 aaatggatgt tatggaacaa aagctcaaca cattaaaacg gactctggaa aagcgagagc
     1201 aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt tatgtacttg gcgcacgata
     1261 ttaaaacgcc ccttacatcc attatcggtt atttgagcct gcttgacgag gctccagaca
     1321 tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt ggacaaagcg tatcgactcg
     1381 aacagctaat cgacgagttt tttgagatta cacggtataa cctacaaacg ataacgctaa
     1441 caaaaacgca catagaccta tactatatgc tggtgcagat gaccgatgaa ttttatcctc
     1501 agctttccgc acatggaaaa caggcggtta ttcacgcccc cgaggatctg accgtgtccg
     1561 gcgaccctga taaactcgcg agagtcttta acaacatttt gaaaaacgcc gctgcataca
     1621 gtgaggataa cagcatcatt gacattaccg cgggcctctc cggggatgtg gtgtcaatcg
     1681 aattcaagaa cactggaagc atcccaaaag ataagctagc tgccatattt gaaaagttct
     1741 ataggctgga caatgctcgt tcttccgata cgggtggcgc gggacttgga ttggcgattg
     1801 caaaagaaat tattgttcag catggagggc agatttacgc ggaaagcaat gataactata
     1861 cgacgtttag ggtagagctt ccagcgatgc cagacttggt tgataaaagg aggtcctaag
     1921 agatgtatat aattttttag gaaaatctca aggttatctt tactttttct taggaaatta
     1981 acaatttaat attaagaaac ggctcgttct tacacggtag acttaatacc gtaagaacga
     2041 gccgttttcg ttcttcagag aaagatttga caagattacc attggcatcc ccgttttatt
     2101 tggtgccttt cacagaaagg gttggtctta attatgaata acatcggcat tactgtttat
     2161 ggatgtgagc aggatgaggc agatgcattc catgctcttt cgcctcgctt tggcgttatg
     2221 gcaacgataa ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc tttcaatcaa
     2281 tgtatcagtg tgggacataa atcagagatt tccgcctcta ttcttcttgc gctgaagaga
     2341 gccggtgtga aatatatttc tacccgaagc atcggctgca atcatataga tacaactgct
     2401 gctaagagaa tgggcatcac tgtcgacaat gtggcgtact cgccggatag cgttgccgat
     2461 tatactatga tgctaattct tatggcagta cgcaacgtaa aatcgattgt gcgctctgtg
     2521 gaaaaacatg atttcaggtt ggacagcgac cgtggcaagg tactcagcga catgacagtt
     2581 ggtgtggtgg gaacgggcca gataggcaaa gcggttattg agcggctgcg aggatttgga
     2641 tgtaaagtgt tggcttatag tcgcagccga agtatagagg taaactatgt accgtttgat
     2701 gagttgctgc aaaatagcga tatcgttacg cttcatgtgc cgctcaatac ggatacgcac
     2761 tatattatca gccacgaaca aatacagaga atgaagcaag gagcatttct tatcaatact
     2821 gggcgcggtc cacttgtaga tacctatgag ttggttaaag cattagaaaa cgggaaactg
     2881 ggcggtgccg cattggatgt attggaagga gaggaagagt ttttctactc tgattgcacc
     2941 caaaaaccaa ttgataatca atttttactt aaacttcaaa gaatgcctaa cgtgataatc
     3001 acaccgcata cggcctatta taccgagcaa gcgttgcgtg ataccgttga aaaaaccatt
     3061 aaaaactgtt tggattttga aaggagacag gagcatgaat agaataaaag ttgcaatact
     3121 gtttgggggt tgctcagagg agcatgacgt atcggtaaaa tctgcaatag agatagccgc
     3181 taacattaat aaagaaaaat acgagccgtt atacattgga attacgaaat ctggtgtatg
     3241 gaaaatgtgc gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt cagctgtact
     3301 ctcgccggat aaaaaaatgc acggattact tgttaaaaag aaccatgaat atgaaatcaa
     3361 ccatgttgat gtagcatttt cagctttgca tggcaagtca ggtgaagatg gatccataca
     3421 aggtctgttt gaattgtccg gtatcccttt tgtaggctgc gatattcaaa gctcagcaat
     3481 ttgtatggac aaatcgttga catacatcgt tgcgaaaaat gctgggatag ctactcccgc
     3541 cttttgggtt attaataaag atgataggcc ggtggcagct acgtttacct atcctgtttt
     3601 tgttaagccg gcgcgttcag gctcatcctt cggtgtgaaa aaagtcaata gcgcggacga
     3661 attggactac gcaattgaat cggcaagaca atatgacagc aaaatcttaa ttgagcaggc
     3721 tgtttcgggc tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt tagttgttgg
     3781 cgaggtggac caaatcaggc tgcagtacgg aatctttcgt attcatcagg aagtcgagcc
     3841 ggaaaaaggc tctgaaaacg cagttataac cgttcccgca gacctttcag cagaggagcg
     3901 aggacggata caggaaacgg caaaaaaaat atataaagcg ctcggctgta gaggtctagc
     3961 ccgtgtggat atgtttttac aagataacgg ccgcattgta ctgaacgaag tcaatactct
     4021 gcccggtttc acgtcataca gtcgttatcc ccgtatgatg gccgctgcag gtattgcact
     4081 tcccgaactg attgaccgct tgatcgtatt agcgttaaag gggtgataag catggaaata
     4141 ggatttactt ttttagatga aatagtacac ggtgttcgtt gggacgctaa atatgccact
     4201 tgggataatt tcaccggaaa accggttgac ggttatgaag taaatcgcat tgtagggaca
     4261 tacgagttgg ctgaatcgct tttgaaggca aaagaactgg ctgctaccca agggtacgga
     4321 ttgcttctat gggacggtta ccgtcctaag cgtgctgtaa actgttttat gcaatgggct
     4381 gcacagccgg aaaataacct gacaaaggaa agttattatc ccaatattga ccgaactgag
     4441 atgatttcaa aaggatacgt ggcttcaaaa tcaagccata gccgcggcag tgccattgat
     4501 cttacgcttt atcgattaga cacgggtgag cttgtaccaa tggggagccg atttgatttt
     4561 atggatgaac gctctcatca tgcggcaaat ggaatatcat gcaatgaagc gcaaaatcgc
     4621 agacgtttgc gctccatcat ggaaaacagt gggtttgaag catatagcct cgaatggtgg
     4681 cactatgtat taagagacga accatacccc aatagctatt ttgatttccc cgttaaataa
     4741 acttttaacc gttgcacgga caaacggttc tgttgcaaag ttttaaataa agaataaaat
     4801 ccctt
//
LOCUS       DAZKPE010000267         3257 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.152, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000267 DAZKPE010000000
VERSION     DAZKPE010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.152"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            184..1398
                     /locus_tag="ACG930_003160"
     CDS             184..1398
                     /locus_tag="ACG930_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFQ0520221.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1429..1668
                     /locus_tag="ACG930_003161"
                     /pseudo
     CDS             1429..1668
                     /locus_tag="ACG930_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
     gene            2066..2561
                     /gene="dfrF"
                     /locus_tag="ACG930_003162"
                     /pseudo
     CDS             2066..2561
                     /gene="dfrF"
                     /locus_tag="ACG930_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
     gene            2666..>3257
                     /locus_tag="ACG930_003163"
     CDS             2666..>3257
                     /locus_tag="ACG930_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HFQ0520222.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMP"
BASE COUNT         1061 a          481 c          699 g         1016 t
ORIGIN      
        1 ctataaaaag aagaccgttt attttttgtc tttatttgtg tgaaaaacga aaaagagcac
       61 aacacatcaa gcttttatta attgtctgtc ttttataaat gcaagtatta attcaaaaaa
      121 acagaagaaa aaaacaacta caccttcttt tatactcgta atcgtagaaa ggaggcgaaa
      181 aaaatgaata cattacctat caatacagga gatacagcat tcatgatttt atgtacagca
      241 atggtttgcc tgatgactcc tggtctagct tttttttacg gcggattagc acggaagaat
      301 aatatactaa cgatcatgtc tcaatctttt ctctccgttg ggataacaac gattatgtgg
      361 gtatttggtg gattcggatt ggcctttgga cgggatatcg gcggtgttat tggaaacccg
      421 gcagatttct ttttgatgag acatgttaca agcttcccca acatgtttca tggtgcaacg
      481 attccatttt taatgttctt tctttaccaa ctgatgttta tcgtgattac cgttcctttg
      541 atgacaggag cttttgcagg gagattgaat ttaaaaggct atattatact tgttattttt
      601 tggaatctgc tgatttattt ccctgtttgc cactggatat ggggtggcgg atttttggat
      661 cagatgggat ttagagattt cgctggtgga gcagtcatcc acacgacagc tggattcggc
      721 tctttagcat gtatcctcac acttggtcaa agaaagattc ctttaggaga aagaagtcag
      781 catagcagtc ttatggcagc tgctatcggt acaggactgc tttggtttgg ctggttcggt
      841 tttaattccg gtggtgcact tcgagcagat gaacaagcag tcaatgcatt tggttcaaca
      901 ttcatcgctc ttgcatttgc gatgattact tggctgatca ttgcaaaagt aaaaggaaat
      961 ggctttgatt ttgtcgacgt actaacagga tccgttgctg gattggcagc cattacgcct
     1021 tgtgccggtt atgtagaagc aaaaagtgcc atgctgattg ggatcattgc gggtatcgtc
     1081 tgtcatgctg ctgttgattt tcgtaaaaag aaacaatggg atgatgcact tgatgtgtgg
     1141 ggtgttcatg gcatgggcgg attcacaggt acgattctga tagggatctt tgcatctaac
     1201 agccatttac taacgaatcc aagcagctgg tacttcttag ggattcaagt gattggtgtc
     1261 atcattactg ccgtgtatgc ctatgtgctg acaacagtga ttttaaaatc ggcgatgcac
     1321 tttacaacga tcactactac aaaagaagaa caagaagaag gattggactt tttcttcttt
     1381 ggcaacaaac tcaattgaaa caaattcaaa tagaaaagag gaagattcat gcaacaaagc
     1441 aaaacgaaaa ttcctgcaaa aaaattaacg ttctttggct ttttggctat gaccatctca
     1501 atggtcgttt cattatatga atatcccaca ttcgcgacct caggcttcag cttagtattt
     1561 ttcttgttat taggcggttt gctatggttt atccctgtgg cattgtgcgc agcagagatg
     1621 gcaacggtga aaggatggga aaaaggtgtt tcccaaacaa aaagatatta agaaacagcc
     1681 catgtttacc tgcttgcaaa caaaagaata ttgctactag actaagagat actacataag
     1741 tgtgttggta tctctttttt gttgccgtga aacagcagac tatttcattt ctgcttgatt
     1801 accttaaaac ttattagtct atggtttgtc aagggcttgt tgcgtgagaa atgctgaata
     1861 tcacccttta caaaacatag gctgataagt aacttttcaa aagcagaaaa gaaatggcaa
     1921 tgcttataac aatatgatat aatgcagatg aagacaaaaa aggaatttgt cgagctggtt
     1981 agttcgagat aattttgagt ttgttaagat gtggtgcact tgatggaatc acaggtacga
     2041 catcatatta tggaggatga aatagatgat aggtttgatt gttgcgaggt caaagaataa
     2101 tgttataggc aagaatggta atataccatg gaaaataaag ggagaacaaa agcaatttag
     2161 agagttaaca acgggtaatg tggttattat ggggcgaaag tcttatgaag aaatcggtca
     2221 tccgttgcct aatagaatga atattgttgt ttccaccaca acagagtatc aaggagataa
     2281 tttagtttca gttaaatcat tagaagatgc attattattg gctaaaggac gagatgtata
     2341 catatctggt ggatatggac tatttaagga agctttgcaa atagtagata aaatgtatat
     2401 cacagaagta gatttaaata ttgaagatgg agatacattc tttccagaat ttgatatcaa
     2461 tgattttgaa gttttgatag gggaaacact tggtgaggaa gtgaaatata cgagaacatt
     2521 ttatgtaagg aaaaaatgaa ttgagtaaat tttggattta gggtgttttc ataaatatat
     2581 tgctttttat gcatatataa attgttgtaa gacaaattcc agtttgtatg gggcgataaa
     2641 atcagaattt gagagaggat tgaatatgaa taaggaatgg tctgaactta ataaaacaat
     2701 gcaggcacaa ataaaaaaga aagatactta taagaggggt attgatactt tacttacttt
     2761 acgaagtcag ttaatacaaa ccttagtatc tttcaaagaa gaattatgca gagaagattt
     2821 taactcaatc cccttcataa acgctgatgg ttatcatagt aagacgattg cttattctat
     2881 ttggcatatt ttccgcattg aagatatagt tgtgcataca gtgataaatg aagatgaaca
     2941 agtatttttt gcaggcaatt atcaagagcg tatcaattca cctatcatta caacaggaaa
     3001 tgaactcatg aaacagcaga ttgcagactt ttcaaaacag cttaatctgg aagaattata
     3061 tttatatatt ttcgaagtat gggaaagcac tgagaaaatg cttgaacggt tatcttatga
     3121 tgaattgaaa agaaaaatac cgaaagaaag aaaaggatac ttagaatcgt tgaatgtagt
     3181 aaacgacaat gaaaaagcaa tttggctgat tgattattgg tgtaataaag atatttgtgg
     3241 actaattcaa atgccgt
//
LOCUS       DAZKPE010000268         2934 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.161, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000268 DAZKPE010000000
VERSION     DAZKPE010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.161"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            92..2011
                     /gene="tet(M)"
                     /locus_tag="ACG930_003164"
     CDS             92..2011
                     /gene="tet(M)"
                     /locus_tag="ACG930_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFQ0520223.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2130..2297
                     /locus_tag="ACG930_003165"
     CDS             2130..2297
                     /locus_tag="ACG930_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFQ0520224.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2357..2710)
                     /locus_tag="ACG930_003166"
     CDS             complement(2357..2710)
                     /locus_tag="ACG930_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFQ0520225.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT          998 a          455 c          570 g          911 t
ORIGIN      
        1 gcctatggtt atgcataaaa atcccagtga taaaagtatt tatcactggg atttttatgc
       61 ccttttgggt ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc
      121 tcatgttgat gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat
      181 tacagaatta ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg
      241 tcagagagga attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt
      301 gaacatcata gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc
      361 agttttagat ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg
      421 tatattattt catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat
      481 tgaccaaaat ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc
      541 cgaaattgta atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac
      601 cgaatctgaa caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat
      661 gtccggtaaa tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa
      721 ttgttctctg ttccctcttt atcatggaag tgcaaaaagt aatataggga ttgataacct
      781 tatagaagtt attactaata aattttattc atcaacacat cgaggtccgt ctgaactttg
      841 cggaaatgtt ttcaaaattg aatatacaaa aaaaagacaa cgtcttgcat atatacgcct
      901 ttatagtgga gtactacatt tacgagattc ggttagagta tcagaaaaag aaaaaataaa
      961 agttacagaa atgtatactt caataaatgg tgaattatgt aagattgata gagcttattc
     1021 tggagaaatt gttattttgc aaaatgagtt tttgaagtta aatagtgttc ttggagatac
     1081 aaaactattg ccacagagaa aaaagattga aaatccgcac cctctactac aaacaactgt
     1141 tgaaccgagt aaacctgaac agagagaaat gttgcttgat gcccttttgg aaatctcaga
     1201 tagtgatccg cttctacgat attacgtgga ttctacgaca catgaaatta tactttcttt
     1261 cttagggaaa gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga
     1321 gatagaacta aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata
     1381 taccattcac atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc
     1441 accgcttccg ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa
     1501 tcaatcgttt caaaatgcag ttatggaggg gatacgctat ggctgtgaac aaggattgta
     1561 tggttggaat gtgacggact gtaaaatctg ttttaagtat ggcttatact atagccctgt
     1621 tagtacccca gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa
     1681 agctggaaca gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata
     1741 tctttcacga gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt
     1801 gaaaaataat gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg
     1861 tagtgattta actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta
     1921 ccatgttact accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa
     1981 agtacgatat atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt
     2041 ttcttgttaa ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg
     2101 agatagttat tataaactac aagtggatat tgtgtcctgt atgtggaaat aaaacacgat
     2161 taaagataag ggaagatact gaattaaaaa aattccccct ctattgtccg aaatgcagac
     2221 aagaaaattt aattgaaata aagcagttca aagtaactgt gattacagag ccagacgcaa
     2281 agacgcagag ccgataaaat gagattaata caatctcatt ttatcggctc tttccgttat
     2341 gtatggattc ttttaattag tcttcgatgt ttcttgcttc gttgataccg ctggctaaag
     2401 attccattaa ggatagttct ttgtctgtaa agctatccat gtatttctct atctgtaatc
     2461 gtcgggtgct ttttaccaag ttattagcag gtaagaaaaa ttcatcaacg gaaacatgaa
     2521 gtaacgatac aaggtcataa agaacttgta tgctggggtg ttgcccttta ttttcaatat
     2581 tagttaagta ccgtgggtca atttcaatca atgctcccac ttgttcacga gttaaacctc
     2641 gtttcaatcg agcttcttta atggctaaac caaaggctct aaaatcatat ttatcttctt
     2701 ttttacgcat agtagaccac ctctatacat tttattgttc ctactgaatt aaaaacaggt
     2761 atagaaaaac gtgttatatg gtttataggt ttatatttaa taaaaagcac tactaaacgc
     2821 caataaaaaa aaccgttata tggtagtgct atttacgctg ttaaaatatt gtatattact
     2881 tccaaatggc ggtttgttgg aggtcaacgt cgccatgaag tacatcatat acaa
//
LOCUS       DAZKPE010000269         2434 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.173, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000269 DAZKPE010000000
VERSION     DAZKPE010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.173"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..92
                     /locus_tag="ACG930_003167"
                     /pseudo
     CDS             6..92
                     /locus_tag="ACG930_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            206..841
                     /locus_tag="ACG930_003168"
     CDS             206..841
                     /locus_tag="ACG930_003168"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFQ0520226.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            948..2186
                     /gene="mef(H)"
                     /locus_tag="ACG930_003169"
                     /gene_synonym="mefH"
     CDS             948..2186
                     /gene="mef(H)"
                     /locus_tag="ACG930_003169"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFQ0520227.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
BASE COUNT          805 a          335 c          430 g          864 t
ORIGIN      
        1 tctgatttgt ggtaaatcag gcaaaggcaa cgcaggtatc acagtatgaa ttgacaccgc
       61 ataaggaaag caactggaag attgtagaat aaatgaaaaa ggcttgcatt ctgcattttt
      121 ataaaattgc aagtctttat attgacaagc ataaaatact aagatatact ttaatcagac
      181 caacggtttg tattggaggt aagttatggc acgaaataaa tatccagaag aaacagtaaa
      241 actcatttta gatgtttcta caaaaatgtt ttgtgaaaaa ggatatgata acacatcatt
      301 gcaagatatt atcaatgaaa caaaactttc taaaggtgct atttatcatc atttcgattc
      361 aaaggaagat attttaaaag caatttttca aagaattgga aatgaaaatg cagtaatatt
      421 tgctaaaatt agagataacg atagtttaaa cggtttagaa aagttaagag aaatatttaa
      481 gacagcggta ttcaattcta accaaagcgt tttattgaca gtttctcctc aactattaaa
      541 caatcctcgt tttcttgcta tgcaaataga acaaatgtat gaaattgtag tacctgaatt
      601 tgttgaaccc gttttagaac aaggtatcaa ggataagtct ttggagattg aaaattcaca
      661 tgaaattgca gaagttatca tggtattaag taatgtatgg ctcaacccat tagttgaaat
      721 gacggataaa gagggtatgg aaaaacgttg caatacattc aatgcccttt taaatggaat
      781 aggcatagac acattattag acgaagaaac aatttctgca tttatacagt tttgtaaata
      841 actgtatttg ttatccctat acgatagact gctctataaa agagcagttt atttaaacca
      901 ttatataaac cgacggtctg tttgattaaa taaaaaggag agattttatg caagcagaaa
      961 aaaaactttt taatcgtgat tttatacttg ttgttatagg acagataatt tctttatttg
     1021 gaaacgctat cctacgattt gcattaccgt actatttgtt aaaagaaact ggttcatcag
     1081 ctttgtttgg tattgctaca gcctgctctt ttttacctat ggttattttg tcgctggtag
     1141 gtggtattat tgctgacagg acaaataaaa gaaacattat ggtcatacta gattttgtaa
     1201 cagcaatcat aattttagta ttttatttgt cattgggaaa aattcctatc atacctttgt
     1261 ttattgttgc tttgatgtta ctttatggta tttctggtgc atatcaacca gcggtacaag
     1321 caagtattcc tctattggta tcatcagata aacttaccgt cggtaatgct ataataaatc
     1381 aagtaaatac tttagcaaac tttatcggac cagctataag cggagtagtt tttcaatttt
     1441 atggtatcaa tcccatttta attgttagta ttatatgttt tactttttca gccattatgg
     1501 aaatttttat ccatattcca caccaaaaaa gacctcgtga agtaggtgta attgcagttg
     1561 ctaaaaacga tttaaaagat agttatacct ttttgaaaaa ggagaaaccc atttttatat
     1621 ccgtaatctt tttggtttgc attttcaatt tggttttaag tgctgtttta attgttggtc
     1681 tgcctatctt aatttctgaa gttttaaaaa tgccagatac actatatggt ttttcacaat
     1741 cagcattatc attaggtggt ttatgtggtg gtattttaac agctcttgtt gcttcaaagt
     1801 taaaactaaa aaacctttat accttgttac ttatttgttc tgtttctgtt ttacttatgg
     1861 gaatttcgct atttttagaa ttgcctgcaa tagtttccta ctgggtagtt acagtgatgt
     1921 gctttgtggc tatgggtgta tctactatgt ttgttgttca aatttacact cttgttcaga
     1981 cacaaacacc accgcaatta gtaggaaaga taatggctac gctggtagca gttgctatgt
     2041 gcggtcaacc tattggacaa atggtttacg gtattttatt cgatgtattt atacaagaaa
     2101 catgggttgt tatgtttgta gcttctattg cttcaatcat gatttcaata tattcaaaaa
     2161 gaatttttca aaagttagag atataataca aggggttaaa tagtatgtta ggctaaaaac
     2221 aatatataaa agaaaatttg aaatctgcta aaaggatagt gttataaaag aaagagtaat
     2281 attgcagtat ttaaggctcg cacaaatata tgttttgtgt gggctttttt cttaccattt
     2341 ttctgtattt ctaaagggta taaacggtat tccgtttata tatttcagca ttagcagaaa
     2401 gggggtgaga ttatgaggac atcttctttc gagc
//
LOCUS       DAZKPE010000270         2348 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.178, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000270 DAZKPE010000000
VERSION     DAZKPE010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.178"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..341)
                     /locus_tag="ACG930_003170"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACG930_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACG930_003171"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACG930_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACG930_003172"
     CDS             complement(1055..1345)
                     /locus_tag="ACG930_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFQ0520228.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2245)
                     /locus_tag="ACG930_003173"
     CDS             complement(1553..2245)
                     /locus_tag="ACG930_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFQ0520229.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          677 a          441 c          337 g          893 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgagttt ctacatttgt tttttcttgt gtcagtgttg
     1741 cgatttgttg attcaaacca tttacagtat tttgtaattc tgaaagtttt gcttgtgctt
     1801 cttgtagtct tgctgtccaa tctgcattca gatgattgat ttcatcattt ttttggttga
     1861 tctcatctag tttgacattg atttcatttt gtttgctttg tagttgtgca tccttgctga
     1921 ctaattgact ttctaagttt tgtttttctg ctgccgattg atttttttgg ttttctaatt
     1981 catttacttt tgtttggtat tcttggacat ctgcctttga atcttgcaat gtctgttctt
     2041 tttgtgctag tcgagcggta agatctgtaa tcgcttgctc tttatctgtc aatgtatgat
     2101 caagctgtgt cagattctca ttgattgtat caatatctgt ctctccaccc cacaaaataa
     2161 tttcatttgc gtaccgcgtg cctgtgtagc caattagaca tagaaatgca acgacaatcc
     2221 caccagtaat aaatttcttt ttcatttgca tagctcctta atccaatact tttacatgct
     2281 aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa attacatatg taattttaat
     2341 ataaatac
//
LOCUS       DAZKPE010000271         2304 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.179, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000271 DAZKPE010000000
VERSION     DAZKPE010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.179"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..790
                     /locus_tag="ACG930_003174"
     CDS             56..790
                     /locus_tag="ACG930_003174"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0520230.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            823..1731
                     /locus_tag="ACG930_003175"
     CDS             823..1731
                     /locus_tag="ACG930_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0520231.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1728..2270
                     /gene="sat4"
                     /locus_tag="ACG930_003176"
     CDS             1728..2270
                     /gene="sat4"
                     /locus_tag="ACG930_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFQ0520232.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
BASE COUNT          807 a          329 c          523 g          645 t
ORIGIN      
        1 gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa
       61 agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca
      121 gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa
      181 gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga
      241 aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa
      301 aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt
      361 cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta
      421 tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac
      481 agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg
      541 agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt
      601 tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct
      661 ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga
      721 tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa
      781 gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa
      841 atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat tgtgaccctt
      901 gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta tgatattaca
      961 tattttgtaa gtgatataga accgtttata tctaatgatg actggcttaa tcaatttggg
     1021 aatataataa tgatgcaaaa gccggaggat atggaattat tcccacctga agaaaaggga
     1081 ttttcctatc ttatgctatt tgatgattac aataaaattg atcttacctt attgcccttg
     1141 gaagagttag ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat
     1201 tgtagaatta aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc
     1261 gcaagggagt atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa
     1321 ggattgtgcc gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat
     1381 gagctgctga gaatgatatc atggaaggtc ggcatcgaaa caggctttaa attaagtgta
     1441 ggcaagaact ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg
     1501 tccacctacc ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa
     1561 ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat
     1621 gataggaata taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc
     1681 tgcctggata gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa
     1741 tgaaagcagg gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta
     1801 agattatacc gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc
     1861 catatttaaa aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg
     1921 aatatattga caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg
     1981 gaaaagttaa actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat
     2041 gtaaggattt cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg
     2101 caaagcataa aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt
     2161 gtaaattcta tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca
     2221 actttgaaaa caactttgaa aaagctgttt tctggtattt aaggttttag aatgcaagga
     2281 acagtgaatt ggagttcgtc ttgt
//
LOCUS       DAZKPE010000272         2242 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.183, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000272 DAZKPE010000000
VERSION     DAZKPE010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.183"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..790
                     /locus_tag="ACG930_003177"
     CDS             56..790
                     /locus_tag="ACG930_003177"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFQ0520233.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            823..1731
                     /locus_tag="ACG930_003178"
     CDS             823..1731
                     /locus_tag="ACG930_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFQ0520234.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1728..2208
                     /locus_tag="ACG930_003179"
                     /pseudo
     CDS             1728..2208
                     /locus_tag="ACG930_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT          782 a          317 c          509 g          634 t
ORIGIN      
        1 gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa
       61 agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca
      121 gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa
      181 gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga
      241 aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa
      301 aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt
      361 cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta
      421 tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac
      481 agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg
      541 agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt
      601 tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct
      661 ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga
      721 tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa
      781 gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa
      841 atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat tgtgaccctt
      901 gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta tgatattaca
      961 tattttgtaa gtgatataga accgtttata tctaatgatg actggcttaa tcaatttggg
     1021 aatataataa tgatgcaaaa gccggaggat atggaattat tcccacctga agaaaaggga
     1081 ttttcctatc ttatgctatt tgatgattac aataaaattg atcttacctt attgcccttg
     1141 gaagagttag ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat
     1201 tgtagaatta aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc
     1261 gcaagggagt atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa
     1321 ggattgtgcc gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat
     1381 gagctgctga gaatgatatc atggaaggtc ggcatcgaaa caggctttaa attaagtgta
     1441 ggcaagaact ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg
     1501 tccacctacc ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa
     1561 ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat
     1621 gataggaata taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc
     1681 tgcctggata gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa
     1741 tgaaagcagg gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta
     1801 agattatacc gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc
     1861 catatttaaa aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg
     1921 aatatattga caatactgat aagataatat atcttttata tagaagatat cgccgtatgt
     1981 aaggatttca gggggcaagg cataggcagc gcgcttatca atatatctat agaatgggca
     2041 aagcataaaa acttgcatgg actaatgctt gaaacccagg acaataacct tatagcttgt
     2101 aaattctatc ataattgtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac
     2161 tttgaaaaca actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac
     2221 agtgaattgg agttcgtctt gt
//
LOCUS       DAZKPE010000273         1847 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.191, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000273 DAZKPE010000000
VERSION     DAZKPE010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.191"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            99..893
                     /locus_tag="ACG930_003180"
                     /note="aph(3')-IIIa"
     CDS             99..893
                     /locus_tag="ACG930_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFQ0520235.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1169..1300
                     /locus_tag="ACG930_003181"
                     /pseudo
     CDS             1169..1300
                     /locus_tag="ACG930_003181"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            1472..1847
                     /locus_tag="ACG930_003182"
                     /pseudo
     CDS             1472..1847
                     /locus_tag="ACG930_003182"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT          610 a          297 c          443 g          497 t
ORIGIN      
        1 ttttagaatg caaggaacag tgaattggag ttcgtcttgt tataattagc ttcttggggt
       61 atctttaaat actgtagaaa agaggaagga aataataaat ggctaaaatg agaatatcac
      121 cggaattgaa aaaactgatc gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc
      181 ctgctaaggt atataagctg gtgggagaaa atgaaaacct atatttaaaa atgacggaca
      241 gccggtataa agggaccacc tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg
      301 aaggaaagct gcctgttcca aaggtcctgc actttgaacg gcatgatggc tggagcaatc
      361 tgctcatgag tgaggccgat ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc
      421 ctgaaaagat tatcgagctg tatgcggagt gcatcaggct ctttcactcc atcgacatat
      481 cggattgtcc ctatacgaat agcttagaca gccgcttagc cgaattggat tacttactga
      541 ataacgatct ggccgatgtg gattgcgaaa actgggaaga agacactcca tttaaagatc
      601 cgcgcgagct gtatgatttt ttaaagacgg aaaagcccga agaggaactt gtcttttccc
      661 acggcgacct gggagacagc aacatctttg tgaaagatgg caaagtaagt ggctttattg
      721 atcttgggag aagcggcagg gcggacaagt ggtatgacat tgccttctgc gtccggtcga
      781 tcagggagga tatcggggaa gaacagtatg tcgagctatt ttttgactta ctggggatca
      841 agcctgattg ggagaaaata aaatattata ttttactgga tgaattgttt tagtacctag
      901 atttagatgt ctaaaaagct ttaactacaa gctttttaga catctaatct tttctgaagt
      961 acatccgcaa ctgtccatac tctgatgttt tatatctttt ctaaaagttc gctagataga
     1021 gttctatatt agagatgtaa agagttttgg tgaagaggtt tgtgagtatg gcttttataa
     1081 ccagggtgca atgagaagca ctaacagcag ctagcttaag aacgcatagg atatactttt
     1141 tatggaagtc acagaggagg aataaaattt gaacaggatt aacagagtaa cctctattct
     1201 tattcagctg caatcaaaaa aaataattcc tgccaaagaa attgcacagc gatttaatat
     1261 aagcttaagg acagtttaca gagatatccg gacacttgaa gaagccggaa taccaattgg
     1321 atctgaggcc ggaaaaggat attttcttgt agagggcttc ctacttccgc cggtaatgtt
     1381 tacagcggcg gaagtgggtg cattgattac agcagggaaa tttttaaatt gccatggaga
     1441 tgaatcattt ataaaggatt ttgattcagc tatgtataaa atcaaatcta ttttgaagca
     1501 tggtgaaaaa aactatgcac aggagttgga gaacagtatt aacgtgtaca gcacatctgg
     1561 acagaaaaat acattggcgg ataacgttat tgcagcaatt cagactgcaa tctgcaataa
     1621 aagggtaata tcaattcaat atcctgcatc aggagggcaa gaaccggaaa gcagaatgat
     1681 agagcctata tcactggggt tttatgaaca gaactggtac ttaatcggtt ttgcaggcta
     1741 agaaatgaat ataggaattt tcgtgtggat cggattaaaa gcatttgcat agaagaagag
     1801 ctctgtcaaa gccatgatgg ctctttggaa caaatattaa aacaaat
//
LOCUS       DAZKPE010000274         1571 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.197, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000274 DAZKPE010000000
VERSION     DAZKPE010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.197"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            42..1481
                     /locus_tag="ACG930_003183"
                     /note="aph(2'')-Ia"
     CDS             42..1481
                     /locus_tag="ACG930_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFQ0520236.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          673 a          112 c          267 g          519 t
ORIGIN      
        1 aaatagtata tgtatatgat tatgaaaaag gtgataaata aatgaatata gttgaaaatg
       61 aaatatgtat aagaacttta atagatgatg attttccttt gatgttaaaa tggttaactg
      121 atgaaagagt attagaattt tatggtggta gagataaaaa atatacatta gaatcattaa
      181 aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt gaatataaca
      241 atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat actgattatc
      301 attatccaaa aactgatgag atagtctatg gtatggatca atttatagga gagccaaatt
      361 attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt ttgaaaaaag
      421 aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga gcaataaggg
      481 cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa ttacacgagg
      541 gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc acaaatgtta
      601 aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat agtattgaaa
      661 taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac atttttaaaa
      721 caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata tataattttt
      781 taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg tatattagtg
      841 atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca ccagaaattt
      901 attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc agttttttaa
      961 gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat aataaacaaa
     1021 atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta actgatatag
     1081 aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt tttgagggta
     1141 aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat ggcaataata
     1201 gattaactgg aataattgat tttggagatt ctggaattat agatgaatat tgtgatttta
     1261 tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa gatatattaa
     1321 gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata gttgaagaat
     1381 attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa tttatcgaaa
     1441 atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat atatgaaaag
     1501 ctattataaa agacattagt attaaatagt ttaaaaaaat tcaaaatctt tcagagaagc
     1561 tgttaaagga a
//
LOCUS       DAZKPE010000275         1027 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.219, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000275 DAZKPE010000000
VERSION     DAZKPE010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.219"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..504
                     /locus_tag="ACG930_003184"
     CDS             <1..504
                     /locus_tag="ACG930_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatA-like O-acetyltransferase"
                     /protein_id="HFQ0520237.1"
                     /translation="IYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNK
                     QTEKFTNIWTESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFS
                     SFNLNIGNNSSFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDII
                     HRVDDWI"
BASE COUNT          357 a          127 c          163 g          380 t
ORIGIN      
        1 atttatccct ctttaattta tgcaattatg gaagttgtaa ataaaaataa agtgtttaga
       61 acaggaatta atagtgagaa taaattaggt tattgggata agttaaatcc tttgtataca
      121 gtttttaata agcaaactga aaaatttact aacatttgga ctgaatctga taaaaacttc
      181 atttcttttt ataataatta taaaaatgac ttgcttgaat ataaagataa agaagaaatg
      241 tttcctaaaa aaccgatacc tgaaaacacc ataccgattt caatgattcc ttggattgat
      301 tttagttcat ttaatttaaa tattggtaac aatagcagct ttttattgcc tattattacg
      361 ataggtaaat tttatagtga gaataataaa atttatatac cagttgctct gcaacttcat
      421 cattctgtat gtgatggtta ccatgcttca ctatttatga atgaatttca agatataatt
      481 catagggtag atgattggat ttagttttta gattttgaaa gtgaatttaa ttttatacac
      541 gtaagtgatc ataaaattta tgaacgtata acaaccacat tttttggttg cttgtggttt
      601 tgattttgaa tttggttttg aacttatgga ctgatttatt cagtccattt tttgtgcttg
      661 cacaaaaact agcctcgcag agcacacgca ttaatgactt atgaaacgta gtaaataagt
      721 ctagtgtgtt atactttact tggaagatgc accgaataaa aaatattgaa gaacaactag
      781 caaaagattt taaagagtta ttttatttta agtctttata acatgagtga agcgaatttt
      841 taaatttcga tagaaatttt tacatcaaaa agccccctgt caaaattgac gaagggggtt
      901 ttttggcgca cgcttttcgt tagaaatata caagattgaa aatcgtgtat aagtgcgccc
      961 tttgttttga acttagcacg ttacatcaat tttttaaaat gatgtataag tgcgcccttt
     1021 taaattt
//
LOCUS       DAZKPE010000276          954 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.227, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000276 DAZKPE010000000
VERSION     DAZKPE010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.227"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            7..744
                     /gene="erm(B)"
                     /locus_tag="ACG930_003185"
     CDS             7..744
                     /gene="erm(B)"
                     /locus_tag="ACG930_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFQ0520238.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          347 a          169 c          162 g          276 t
ORIGIN      
        1 gattacatga acaaaaatat aaaatattct caaaactttt taacgagtga aaaagtactc
       61 aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga aattggaaca
      121 ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac gtctattgaa
      181 ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaacat tcgtgtcact
      241 ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta taaaattgtt
      301 gggagtattc cttaccattt aagcacacaa attattaaaa aagtggtttt tgaaagccat
      361 gcgtctgaca tctatctgat tgttgaagaa ggattctaca agcgtacctt ggatattcac
      421 cgaacactag ggttgctctt gcacactcaa gtctcgattc agcaattgct taagctgcca
      481 gcggaatgct ttcatcctaa accaaaagta aacagtgtct taataaaact tacccgccat
      541 accacagatg ttccagataa atattggaag ctatatacgt actttgtttc aaaatgggtc
      601 aatcgagaat atcgtcaact gtttactaaa aatcagtttc atcaagcaat gaaacacgcc
      661 aaagtaaaca atttaagtac cgttacttat gagcaagtat tgtctatttt taatagttat
      721 ctattattta acgggaggaa ataattctat gagtcgcttt tttaaatttg gaaagttaca
      781 cgttactaaa gggaatggag ataaattatt agatatacta ctgacagctt ccaagaagct
      841 aaagaggtcc ctagcgccta cggggaattt gtatcgataa ggggtacaaa ttcccactaa
      901 gcgctcggga ccccttgtag gaaaatgtcc taagtgtggc aacaatattg tatt
//
LOCUS       DAZKPE010000277          954 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.228, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000277 DAZKPE010000000
VERSION     DAZKPE010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.228"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            7..744
                     /gene="erm(B)"
                     /locus_tag="ACG930_003186"
     CDS             7..744
                     /gene="erm(B)"
                     /locus_tag="ACG930_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFQ0520239.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          348 a          169 c          161 g          276 t
ORIGIN      
        1 gattacatga acaaaaatat aaaatattct caaaactttt taacgagtga aaaagtactc
       61 aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga aattggaaca
      121 ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac gtctattgaa
      181 ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaatac tcgtgtcact
      241 ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta taaaattgtt
      301 gggaatattc cttaccattt aagcacacaa attattaaaa aagtggtttt tgaaagccgt
      361 gcgtctgaca tctatctgat tgttgaagaa ggattctaca agcgtacctt ggatattcac
      421 cgaacactag ggttgctctt gcacactcaa gtctcgattc agcaattgct taagctgcca
      481 gcggaatgct ttcatcctaa accaaaagta aacagtgtct taataaaact tacccgccat
      541 accacagatg ttccagataa atattggaag ctatatacgt actttgtttc aaaatgggtc
      601 aatcgagaat atcgtcaact gtttactaaa aatcagtttc atcaagcaat gaaacacgcc
      661 aaagtaaaca atttaagtac cattacttat gagcaagtat tgtctatttt taatagttat
      721 ctattattta acgggaggaa ataattctat gagtcgcttt tttaaatttg gaaagttaca
      781 cgttactaaa gggaatggag ataaattatt agatatacta ctgacagctt ccaagaagct
      841 aaagaggtcc ctagcgccta cggggaattt gtatcgataa ggggtacaaa ttcccactaa
      901 gcgctcggga ccccttgtag gaaaatgtcc taagtgtggc aacaatattg tatt
//
LOCUS       DAZKPE010000278          889 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3365
            SAMEA115706665-rid22584253.guided.232, whole genome shotgun
            sequence.
ACCESSION   DAZKPE010000278 DAZKPE010000000
VERSION     DAZKPE010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706665
            Sequence Read Archive: ERR13196400
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287726.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287726.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 12:56:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,187
            CDSs (total)                      :: 3,122
            Genes (coding)                    :: 3,039
            CDSs (with protein)               :: 3,039
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 34 of 83
            Pseudo Genes (incomplete)         :: 46 of 83
            Pseudo Genes (internal stop)      :: 21 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706665-rid22584253.guided.232"
                     /isolate="VRE3365"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            276..824
                     /gene="aac(6')"
                     /locus_tag="ACG930_003187"
     CDS             276..824
                     /gene="aac(6')"
                     /locus_tag="ACG930_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFQ0520240.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          317 a          129 c          186 g          257 t
ORIGIN      
        1 gaaaacaggt tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat
       61 atcatgatga acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt
      121 ttgaataaag tgtttctgta taattttttt attttataag taagataaat aatgaaagaa
      181 tagagatact gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg
      241 actgttagaa taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta
      301 ataatccagt attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat
      361 atggagacag ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag
      421 cagcggtaga ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca
      481 caggttggga attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta
      541 ctcgattagt caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt
      601 taggtacgga tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata
      661 catttgataa agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa
      721 aattaggtta taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata
      781 tttggatggc aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga
      841 cagaagtaat cagcttcaag aaataagaag gaatttacga aaattactt
//
